Patent SG-11201808014S-A (SG)
Title: Compositions, devices, and methods for cell separation
Inventor: KEVLAHAN SEAN
IPC: G01N33/53
Filed: 2017-03-20
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property -, Organization 111111110111101110101011111010111110111011110110111111111011111101111011111 International Bureau ..... ._)d (10) International Publication Number (43) International Publication Date ..... ..,./ WO 2017/161371 Al 21 September 2017 (21.09.2017) WIP0 I PCT (51) International Patent Classification: KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, GO1N 33/574 (2006.01) G01N 33/48 (2006.01) MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, GO1N 33/53 (2006.01) C07K 16/28 (2006.01) NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, (21) International Application Number: TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, PCT/US2017/023207 ZA, ZM, ZW. (22) International Filing Date: (84) Designated States (unless otherwise indicated, for every 20 March 2017 (20.03.2017) kind of regional protection available): ARIPO (BW, GH, (25) Filing Language: English GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, (26) Publication Language: English TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, (30) Priority Data: DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, 62/310,360 18 March 2016 (18.03.2016) US LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, (71) Applicant: QT HOLDINGS CORP [US/US]; 100 Cum- GW, KM, ML, MR, NE, SN, TD, TG). mings Center, Suite 438N, Beverly, MA 01915 (US). Declarations under Rule 4.17: (72) Inventors: KEVLAHAN, Sean, H.; 8 Porter Road, North — as to applicant's entitlement to apply for and be granted a Reading, MA 01864 (US). BALL, Andrew; 6 London- deny Lane, Georgetown, MA 01833 (US). QIN, Guokui; patent (Rule 4.17(u)) 379 Broodway, Apt. 57, Somerville, MA 02145 (US). — as to the applicant's entitlement to claim the priority of the — WELLS, Steven, B.; 15 Glenville Ave #6, Allston, MA earlier application (Rule 4.17(iii)) 02134 (US). — of inventorship (Rule 4.17(iv)) (74) Agent: MCDONALD, J. Cooper; Clark & Elbing LLP, Published: _ 101 Federal Street, 15th Floor, Boston, MA 02110 (US). = — with international search report (Art. 21(3)) (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, before the expiration of the time limit for amending the = AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, claims and to be republished in the event of receipt of BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, amendments (Rule 48.2(h)) DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, = = HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, = = Title: COMPOSITIONS, DEVICES, AND METHODS FOR CELL SEPARATION = (54) = Figure 1 = = = kIkenl , ..:..4,... t ,e.Aanen Ami ;,.-, ; ,,,,ii Mite3 , ..ti t,ssdittg Ism n ,.%:: Lz.:iMment UM: CO R. , ,,,NA .4 Il en Si :1:, • ::B1 ii ice :'* l i „1r. *. , • ,t , -...o/ , 1 - 1 : ,tD i,,. I stasmteme. I smi rett nips-ts, A 11 IN 1-1 (57) : The invention features a substrate and compositions, kits, devices, and methods employing the substrate that pro - 0 duces an isolated population of cells from a general population. The isolated population is enriched for one or more target popula - N tions. Substrate is can be liquefied and allows recovery of unlabeled, viable, and functional cells.