baber/WOPTO huggingface dataset:
Patent DK-1948822-T3 (DK)
Inventor: BIRKETT DONALD JOHN
IPC: C12Q1/68
Filed: 2006-10-06
Granted: 2011-10-17
Abstract: The present invention relates to Multicomponent Nucleic Acid Enzymes (MNAzymes) and methods for their use. MNAzymes comprise two or more oligonucleotide components which self-assemble in the presence of one or more MNAzyme assembly facilitator molecules to form a catalytically active structure. Compositions for making MNAzymes, and collections of MNAzymes are provided. Also provided are methods for using MNAzymes for the detection, identification and/or quantification of one or more targets. The methods can be practiced in solution-based assays or in assays where one or more reaction components are attached to a support structure. The methods allow for multiplexing the MNAzyme detection to detect multiple targets in a single reaction. Also provided are kits for making the compositions, and for practicing the methods provided herein.
Patent DK-1926729-T3 (DK)
Inventor: COWART MARLON D
IPC: A61K31/428
Filed: 2006-09-19
Granted: 2012-03-19
Abstract: Compounds of formula (I) are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions comprising the histamine-3 receptor ligands, methods for using such compounds and compositions, and a process for preparing compounds within the scope of formula (I).
Patent DK-2000465-T3 (DK)
Inventor: KIRA KAZUNOBU
IPC: A61K31/4196
Filed: 2007-03-22
Granted: 2011-02-07
Abstract: A Compound represented by the following general formula (1), salts thereof or hydrates of the foregoing is a novel compound useful for treatment and/or prevention of diseases associated with thrombus formation, and which is safer with suitable physicochemical stability.   
[wherein R 1a , R 1b , R 1c  and R 1d  each independently represent hydrogen, etc.; R 2  represents optionally substituted phenyl, etc.; R 3  represents optionally substituted C6-10 aryl, etc.; and Z 1  and Z 2  each independently represent hydrogen]
Patent DK-2146031-T3 (DK)
Inventor: HILBE LUCA
IPC: E05B13/00
Filed: 2008-07-18
Granted: 2011-07-11
Abstract: A handle device (1) for opening and closing the door of the body of trucks, trailers and the like, comprising at least one base (2) that is coupled to the door and supports rotatably at least one handle (3) which is articulated, at a first end thereof (3a), to at least one rod (A) for actuating means for coupling the door to the frame of the body, and forms, at a second end (3b), at least one grip portion for the operator, the handle (3) being able to rotate manually between at least one angular closure position, in which it is substantially adjacent to the base (2) and in which the coupling means are engaged with the frame of the body, and at least one angular open position, in which the handle (3) is substantially spaced from the base (2) and the coupling means are disengaged from the frame of the body, so as to allow the free opening of the door. The base (2) comprises at least one button (4) for locking and releasing at least one actuator (5) associated with the handle (3), the actuator (5) comprising at least means for detachable anchoring to the base (2) and abutment means that can engage at least one contoured element (6) associated with the base (2), the contoured element (6) being engageable with the handle (3) and being able to rotate selectively, about an axis which is substantially perpendicular to the base (2), from a disengagement configuration, in which it is disengaged from the handle (3) and from the actuator (5), which by not abutting against the contoured element (6) is free to disengage from the base (2) by way of the action of the button (4), so as to allow the opening of the handle (3) and of the door, to an engagement configuration, in which it is engaged with the handle (3), so as to fasten it on the base (2), and with the actuator (5), so as to lock in engagement the anchoring means with the base (2), in order to retain the handle (3) in the angular position for closing the door.
Patent DK-2223922-T3 (DK)
Title: Inhibitors of HUMANPHOSPHATIDYL-inositol 3-KINASEDELTA
Inventor: SADHU CHANCAL
IPC: C07D487/04
Filed: 2001-04-24
Granted: 2016-06-06
Abstract: Methods of inhibiting phosphatidylinositol 3-kinase delta isoform (PI3K´) activity, and methods of treating diseases, such as disorders of immunity and inflammation, in which PI3K´ plays a role in leukocyte function are disclosed. Preferably, the methods employ active agents that selectively inhibit PI3K´, while not significantly inhibiting activity of other PI3K isoforms. Compounds are provided that inhibit PI3K´ activity, including compounds that selectively inhibit PI3K´ activity. Methods of using PI3K´ inhibitory compounds to inhibit cancer cell growth or proliferation are also provided. Accordingly, the invention provides methods of using PI3K´ inhibitory compounds to inhibit PI3K´-mediated processes in vitro and in vivo.
Patent DK-2434911-T3 (DK)
Inventor: LAMBELET PIERRE
IPC: A23L33/15
Filed: 2010-05-28
Granted: 2018-05-22
Abstract: The present invention relates to a green tea formulation stabilized by natural antioxidants such as OPC together with vitamin C or vitamin C analogs. The invention also relates to the use of a mixture of OPC and ascorbic acid to increase bioavailability of green tea catechins. It also relates to a food, pharmaceutical or cosmetic composition that contains the stabilized green tea formulation.
Patent DK-2532828-T3 (DK)
Title: SYSTEMS AND METHODS FOR DRILLING WITH CONTINUOUS FLOW Gennevilliers
Inventor: BAILEY THOMAS F
IPC: E21B21/12
Filed: 2008-07-25
Granted: 2016-12-19
Abstract: In one embodiment, a method for drilling a wellbore includes injecting drilling fluid into a top of a tubular string disposed in the wellbore at a first flow rate. The tubular string includes: a drill bit disposed on a bottom thereof, tubular joints connected together, a longitudinal bore therethrough, and a port through a wall thereof. The drilling fluid exits the drill bit and carries cuttings from the drill bit. The cuttings and drilling fluid (returns) flow to the surface via an annulus defined between the tubular string and the wellbore. The method further includes rotating the drill bit while injecting the drilling fluid; remotely removing a plug from the port, thereby opening the port; and injecting drilling fluid into the port at a second flow rate while adding a tubular joint or stand of joints to the tubular string. The injection of drilling fluid into the tubular string is continuously maintained between drilling and adding the joint or stand to the drill string. The method further includes remotely installing a plug into the port, thereby closing the port. The first and second flow rates may be substantially equal or different.
Patent DK-2953776-T3 (DK)
Inventor: PEDERSEN MARTIN
IPC: B29C48/13
Filed: 2014-02-07
Granted: 2018-03-19
Abstract: A method for producing an insulated pipe in corrugated casing (100) comprising the steps of: covering an inner pipe assembly (105) comprising at least one inner pipe (101) with a film (106); dispensing an expandable insulation material (102) in a liquid state between the inner pipe assembly (105) and the film (106) thereby preparing an initial pipe assembly (107) comprising a layer of expanding insulation material (102a) positioned between the film (106) and the inner pipe assembly (105); extruding a layer of outer casing (104) onto the initial pipe assembly (105) before the insulation material has expanded completely, thereby creating a still expanding insulated pipe assembly (118); and leading the still expanding insulated pipe assembly (118) through a corrugator (205) having an inner corrugated surface giving the casing (104) a corrugated shape as the at least one layer of expanding insulation material (118) continues to expand.
Patent DK-3092900-T3 (DK)
Inventor: HUNGENBERG HEIKE
IPC: A01P7/00
Filed: 2011-11-30
Granted: 2018-05-22
Abstract: The present invention relates to novel active ingredient combinations which consist of fluopyram and other known active ingredients and are very well suited for the control of animal pests, such as insects and/or unwanted acarids and/or nematodes, in foliar and soil application and/or in the treatment of seeds, and are also suitable for increasing yeilds.
Patent DK-3219312-T3 (DK)
Inventor: LIU MINGJUN
IPC: A61K47/30
Filed: 2005-03-30
Granted: 2019-04-01
Abstract: The present invention provides methods and compositions for the treatment of ion imbalances. In particular, the invention provides compositions comprising potassium binding polymers and pharmaceutical compositions thereof. Methods of use of the polymeric and pharmaceutical compositions for therapeutic and/or prophylactic benefits are disclosed herein. Examples of these methods include the treatment of hyperkalemia, such as hyperkalemia caused by renal failure and/or the use of hyperkalemia causing drugs.
Patent DK-0389388-T3 (DK)
Inventor: BARBEE ROBERT BOYD
IPC: C09D167/00
Filed: 1990-03-09
Granted: 1993-06-14
Abstract: Disclosed are thermosetting, powder coating compositions comprised of blends of certain amorphous polyesters and polyether-esters in combination with a blocked polyisocyanate which, when applied to a substrate and heated, provide cross-linked coatings having a combination of desirable properties including good gloss, impact strength and flexibility.
Patent DK-0396504-T3 (DK)
IPC: F21V29/00
Filed: 1990-04-25
Granted: 1995-04-24
Abstract: The tungsten-halogen lamp holder (3) of the lighting fixture is retained by a mount consisting of two U-profiled parts (6, 7) at a distance behind the reflector shell (1) that can be chosen by displacing the second U-profiled part (7). The reflector shell (1) has an opening (2) through which the tungsten-halogen lamp (4) projects into the reflector chamber (20). The cross-section of the opening (2) is a multiple of the cross-section of the tungsten-halogen lamp, so that a wide annular gap (21) for through-ventilation is free between the tungsten-halogen lamp (4) and the opening rim (9) of the reflector shell (1). In order to form a through-ventilation chamber (22), the mount (6, 7) is completely open to the rear and, moreover, on two opposite sides. The tungsten-halogen lamp holder (3) is freely retained by the mount (6, 7) in the through-ventilation chamber (22) adjoining the annular gap (21), so that the holder (3) is enveloped by the air current flowing through the annular gap (21), and the cap (base) of the tungsten-halogen lamp is cooled. The service life of the tungsten-halogen lighting fixture is thereby substantially increased. 
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Patent DK-0413666-T3 (DK)
Inventor: STEINER EGINHARD DR
IPC: A01N43/36
Filed: 1990-08-09
Granted: 1994-05-16
Abstract: Novel 4-chloro-4,4-difluorobutyric acid derivatives of the formula I <IMAGE>  in which   R1 and R2 independently of one another are hydrogen, C1-C4-alkyl or C1-C4-haloalkyl,   R3 is hydrogen or an organic radical and   X is oxygen or -NR4-,   where R4 represents hydrogen or C1-C6-alkyl, can be employed as pesticides. Insects and arachnids can preferably be controlled.
Patent DK-0425463-T3 (DK)
Inventor: BUNCZK CHARLES J
IPC: A01N59/12
Filed: 1990-10-19
Granted: 1996-03-04
Abstract: A phosphate-free liquid lavatory cleansing and sanitizing composition for use in a metering composition comprising a nonionic or anionic detergent-iodine complex, a nonionic or anionic surfactant in an amount to provide a monomer to micelle ratio of about 90:10 to 40:60, a water-soluble acid dye and water.
Patent DK-0466699-T3 (DK)
Inventor: OIRSCHOT FRANK VAN
IPC: B65G53/50
Filed: 1990-02-01
Granted: 1994-05-02
Abstract: The present invention provides an adjustable venturi device designed for efficient use with blowers of various different capacities. The venturi device of the present invention includes a blower feedable positive air passage and a negative pressure air inlet exposed to and operated by air draw from the positive air passage. The venturi device is adjustable for varying exposure of the air inlet to the positive air passage with resultant varying of the air draw according to capacity of the particular blower used with the venturi device.
Patent DK-0476043-T3 (DK)
Inventor: LIU CHAIN T
IPC: C22C19/05
Filed: 1990-06-07
Granted: 1995-05-22
Abstract: The specification discloses nickel aluminide alloys including nickel, aluminum, chromium, zirconium and boron wherein the concentration of zirconium is maintained in the range of from about 0.05 to about 0.35 atomic percent to improve the ductility, strength and fabricability of the alloys at 1200 DEG  C. Titanium may be added in an amount equal to about 0.2 to about 0.5 atomic percent to improve the mechanical properties of the alloys and the addition of a small amount of carbon further improves hot fabricability.
Patent DK-0434821-T3 (DK)
Inventor: MAIER HANS ERICH
IPC: B65D83/36
Filed: 1990-07-19
Granted: 1995-03-27
Abstract: PCT No. PCT/EP90/01182 Sec. 371 Date Mar. 14, 1991 Sec. 102(e) Date Mar. 14, 1991 PCT Filed Jul. 19, 1990 PCT Pub. No. WO91/01252 PCT Pub. Date Feb. 7, 1991.A pressurizable package for a substance to be dispensed is formed by inserting a flexible liner into a pressurizable container and holding the closure of the container away from the mouth so that the space between the liner and the container can be pressurized with a gas. The closure is then sealed to the container to seal the space and maintain the pressure of gas around the liner which is evacuated to further collapse the liner, by applying a suction to a valve on the closure communicating with the interior of the liner. The liner is then filled through the valve with the substance to further pressurize the gas in the surrounding space.
Patent DK-0480176-T3 (DK)
Inventor: MUELLER WOLFGANG DIPL-ING
IPC: F26B5/14
Filed: 1991-09-06
Granted: 1994-12-05
Abstract: In the case of the known discontinuous drainage processes in which the operating pressure has to be reduced to the surrounding pressure between the removal of the drained sludge cake and the refilling of the drainage apparatus, the filtering action can quickly drop off since fresh raw sludge reaches the drainage chambers only by passing already used filtering surfaces and pushing along in front of it a portion of already predrained sludge cake. The novel process is intended to permit a continuous operation with uniform pressure level and a constant, high filtering capacity while at the same time reducing the possibility of faults arising to a minimum. This is achieved in that the fresh raw sludge (21) is fed at constant pressure in the opposite direction in each case to the direction of movement of the piston (8), in particular in the immediate vicinity of the piston, to the filtering surface shortly after the latter has been swept over by the piston and thereby cleaned. The process and the apparatus for carrying out the process thus make it possible for aqueous sludges to be drained continuously by means of pressure. <IMAGE>
Patent DK-0475307-T3 (DK)
Inventor: PELLON BRIAN JAY
IPC: C08F4/658
Filed: 1991-09-06
Granted: 1996-03-18
Abstract: An elastomeric high molecular weight substantially amorphous propylene homopolymer having a melting point between about 145 DEG C and 165 DEG C, a melt viscosity at 190 DEG C greater than 200,000 cps and a heat of fusion between about 4 cal./gm. and about 10 cal./gm.is disclosed. The polymer comprises from about 35% to about 55% of a diethyl ether soluble fraction, the fraction having an inherent viscosity less than about 1.0 dl/g and exhibiting substantially no isotactic crystallinity and from about 30% to about 70% of a heptane soluble fraction, the fraction having a melting point between about 100 DEG C and 115 DEG C and a heat of fusion less than about 2.0 cal./gm.
Patent DK-0470247-T3 (DK)
Inventor: DORAN NARCISCO O
IPC: C07C237/46
Filed: 1991-02-21
Granted: 1997-10-27
Abstract: An improved process for the reversed phase chromatographic decolorization, separation, and purification of water-soluble, nonionic contrast media compounds from solutions containing nonionic compound impurities involves the steps of (a) packing a chromatographic column with a chromatographic packing material; (b) passing through the column a solution containing a water-soluble, nonionic contrast media compound and nonionic compounds as impurities at a loading ratio between approximately 10 to 1 and 1.5 to 1 wt. packing material/total wt. nonionic compounds; and (c) eluting the column to produce an eluate containing substantially pure, water-soluble, nonionic contrast media compound or MRI agent. The process can be economically practiced on a factory scale and efficiently removes non-polar impurities difficult to remove by conventional methods.
Patent DK-0586372-T3 (DK)
Inventor: SPENCER MARGARET ELIZABETH
IPC: C12R1/19
Filed: 1991-06-07
Granted: 1998-09-07
Abstract: PCT No. PCT/GB91/00913 Sec. 371 Date Jan. 27, 1993 Sec. 102(e) Date Dec. 11, 1992 PCT Filed Jun. 7, 1991 PCT Pub. No. WO91/19800 PCT Pub. Date Dec. 26, 1991A 21 kD protein, and its 23 kD expression precursor, as the source of peptide flavor precursors in cocoa (Theobroma cacao) have been identified. Genes coding for them have been probed, identified and sequenced, and recombinant proteins have been synthesized.
Patent DK-0534536-T3 (DK)
Inventor: SANTANGELO FRANCESCO
IPC: C07C217/74
Filed: 1992-09-17
Granted: 1996-06-24
Abstract: A process is disclosed for the preparation of 2-amino-5,6-dimethoxy-tetralin, which is a useful intermediate for the preparation of pharmacologically active chemical compounds.
Patent DK-0521666-T3 (DK)
Inventor: CHEN SHIH-RUEY THOMAS
IPC: A61K8/00
Filed: 1992-06-26
Granted: 1998-08-24
Abstract: Ampholyte terpolymer conditioning additives for hair care products are disclosed which improve wet and dry hair combability, especially detangling and reduced static flyaway, sheen, and fixative properties, especially curl retention. The ampholyte terpolymers may have a weight average molecular weight of from about 10 thousand to 10 million, and comprise (a) from at least 1 to as much as 95 weight percent of a nonionic monomer, (b) from at least 5 to as much as 80 weight percent of a cationic monomer, and (c) from at least 1 to as much as 75 weight percent of an anionic monomer. In a preferred embodiment, the amount of the cationic and anionic components is such that the overall % net charge of the ampholyte terpolymer is between -5.0 and +5.0. The ampholyte terpolymers are added to hair care product formulations in amounts ranging from 0.1-10% by weight. They are particularly compatible with anionic surfactant shampoos, providing clear formulations without the loss of conditioning properties described above.
Patent DK-0524802-T3 (DK)
Inventor: SUDO MORIHIRO
IPC: B65D1/02
Filed: 1992-07-21
Granted: 1997-04-21
Abstract: A container for a sanitary article capable of stably preserving, while making sure of sanitary property for a long time, materials legally provided by the Japanese Pharmacopoeia, the Food Sanitation Act, etc., for example, pharmaceuticals such as vaccine, antiobiotics, vitamines, sugars, amino acids, electrolytes, etc., materials needing sanitary property, such as nutriments, transfusion liquids, cosmetics, seasonings and other foods is provided. This container comprises a material containing a resin formed of a cyclic olefin compound or a bridged polycyclic hydrocarbon compound, as a polymeric component.
Patent DK-0545678-T3 (DK)
Inventor: BROWN PAUL EDWARD
IPC: B65D83/00
Filed: 1992-12-02
Granted: 2001-04-23
Abstract: A dispensing valve (3) for fluid product packaging comprising: a flange (4); a valve head (5) having a marginal edge (42) and interior and exterior sides (39, 38) and an orifice (6); a resiliently flexible sleeve (7), with one end portion (50) thereof connected with the flange (4), and an opposite head end portion (49) thereof connected with said head (5) adjacent the marginal edge thereof. When pressure is applied to the head the sleeve has a doubled over rolling exterior rim (65) which rolls along the sleeve to be at the head end portion (49) of the sleeve when the sleeve is in a fully extended configuration thereof in which the orifice is closed, forces applied thereafter to the head by the sleeve and pressure in excess of the predetermined discharge pressure causing an unrolling of the doubled over rim (65) as the orifice (6) opens. The valve quickly and accurately achieves a balance between container, valve and fluid product. <IMAGE>
Patent DK-0571422-T3 (DK)
Inventor: NEUSS MALTE
IPC: A61F2/06
Filed: 1992-02-12
Granted: 1994-10-03
Abstract: PCT No. PCT/EP92/00294 Sec. 371 Date Oct. 1, 1991 Sec. 102(e) Date Oct. 1, 1993 PCT Filed Feb. 12, 1992 PCT Pub. No. WO92/14408 PCT Pub. Date Sep. 3, 1992.Spiral implant for organ pathways, in particular for blood vessels, which is formed from a primary spiral made of metal or a primary tube made of an elastic synthetic material whose anterior end is closed and whose cross-section at a distance of 0.5 to 2 mm from the other end of the primary spiral or primary tube is modified for a distance of 0.01 to 10 mm in order to make it possible to reposition the implant. The force required to displace the primary shape on the guide wire serving as an insertion aid amounts to 0.5N to 10N. The invention describes an implant (1) which can be used in vascular surgery or vascular radiology in order to achieve selective blood vessel occlusion. Insertion of the implant (1) into a blood vessel is brought about by means of an insertion catheter (16), with the implant being held in a rectilinear shape by a guide wire (14) slid therein. After the implant has reached the correct position in the organ pathway (18) it assumes a pre-formed spiral shape on the withdrawal of the insertion wire from inside it, thereby ensuring fixation of the implant in the organ pathway.
Patent DK-0538419-T3 (DK)
Inventor: DREYER KURT R
IPC: E05B47/00
Filed: 1992-02-27
Granted: 1997-05-26
Abstract: PCT No. PCT/DE92/00156 Sec. 371 Date Dec. 4, 1992 Sec. 102(e) Date Dec. 4, 1992 PCT Filed Feb. 27, 1992 PCT Pub. No. WO92/15760 PCT Pub. Date Sep. 17, 1992.The invention concerns a lock system for a door, wall, chest, safe or cupboard, etc. The lock system is covered by a cover plate and has a bolt or pin which is linked to a main lever, designed to rotate about a pivot bearing, and which operates in conjunction with a holder plate or bolt. Rotation of the main lever depends on the motion of a first magnetic block mounted on the cover plate. The main lever has at least one bore designed to accommodate at least one locking pin associated with a second magnetic block mounted on the cover plate. The second magnetic block is designed to unlock the lock by pulling the locking pins out of the bores.
Patent DK-0579713-T3 (DK)
Inventor: VIJG JAN
IPC: C12Q1/6897
Filed: 1992-04-02
Granted: 1995-12-04
Abstract: PCT No. PCT/NL92/00062 Sec. 371 Date Dec. 29, 1993 Sec. 102(e) Date Dec. 29, 1993 PCT Filed Apr. 2, 1992 PCT Pub. No. WO92/17605 PCT Pub. Date Oct. 15, 1992Detection of mutations in a lacZ gene including lacZ operator sequence functioning as marker gene located in a plasmid whereof one or more copies are introduced into the DNA of a mammal or of a mammalian cell, by isolating the DNA, cutting the plasmid out of the DNA, picking up the plasmid DNA with solid particles to which a lacZ operator binding material is bound, again releasing the plasmid from the solid particles after isolation and subsequently circularizing the plasmid, transforming a host restriction-negative, lacZ-negative and galE-negative bacterial host with the plasmid and separating transformants with mutated lacZ gene which grow on a lactose-containing medium from transformants with a non-mutated lacZ gene which do not grow on such a medium. A transgenic mammal model for mutation analysis.
Patent DK-0600004-T3 (DK)
Inventor: TSENG MINGCHIH M
IPC: A61C17/00
Filed: 1992-08-13
Granted: 1999-08-16
Abstract: A sustained-release matrix for dental application includes either an anti-microbial agent or a colorant that is released from the matrix when the matrix contacts water. The preferred matrices include a water-soluble polymer and a water-insoluble support resin.