baber/WOPTO huggingface dataset:
Patent AU-2019213484-A1 (AU)
Title: Compounds and compositions for the treatment of pain
Inventor: SCHMITT MARTINE
IPC: C07D405/04
Filed: 2019-02-05
Abstract: The invention relates to compounds, pyridine derivatives, and pharmaceutical 10 compositions containing same for use in the treatment of pain. It also relates to specific compounds, compositions comprising the same and uses thereof, in particular in the treatment of pain.
Patent AU-2019214510-A1 (AU)
Title: Partially-insulated HTS coils
Inventor: SLADE ROBERT
IPC: G21K1/093
Filed: 2019-01-31
Abstract: A high temperature superconducting, HTS, field coil. The HTS field coil comprises a plurality of turns and a partially insulating layer. The plurality of turns comprises HTS material and metallic stabilizer. The partially insulating layer separates the turns, such that current can be shared between turns via the partially insulating layer. The partially insulating layer comprises an electrically conducting layer, and first and second insulating layers. The electrically conducting layer is coated on one side with the first insulating layer and on the other side with the second insulating layer. Each insulating layer has one or more windows through which electrical contact can be made between the turns and the electrically conducting layer. The windows in the first insulating layer are offset in the plane of the electrically conducting strip from the windows in the second insulating layer.
Patent AU-2019262218-A1 (AU)
Title: Natural killer cells engineered to express chimeric antigen receptors with immune checkpoint blockade
Inventor: DAHER MAY
IPC: C07K14/47
Filed: 2019-05-03
Abstract: Provided herein are methods for producing NK cells expressing chimeric antigen receptors and having no expression of CISH. Further provided are methods for treating diseases by administering the CAR NK cells.
Patent AU-2019262648-A1 (AU)
Title: Processes for reducing environmental availability of environmental pollutants
Inventor: ZHOU QUNHUI
IPC: B09C1/00
Filed: 2019-05-03
Abstract: This invention provides processes for reducing the environmental availability of one or more environmental pollutants in solids, liquids, and combinations of solids and liquids.
Patent AU-2019272610-A1 (AU)
Title: Non-rotationally symmetrical spark gap, in particular horn spark gap with deion chamber
Inventor: STRANGFELD UWE
IPC: H01T4/04
Filed: 2019-04-09
Abstract: The invention relates to a non-rotationally symmetrical spark gap, in particular a horn spark gap with a deion chamber, a multi-part insulating material housing (1) as a support and receiving body for the horn electrodes and the deion chamber, means for conducting the gas flow related to the arc, wherein the insulating material housing (1) is divided on the plane defined by the horn electrodes and has two half shells, and plug or screw connections (4, 5) which lead out on the end face. According to the invention, with the exception of the sections of the plug or screw connections (4, 5) leading out, the insulating material housing is surrounded on all sides by a cooling surface (14) which is near the housing and lies against the housing surface, and the cooling surface (14) is at least partly supported on webs (8) which are designed to conduct the gas flow on the outer surface of the half shells.
Patent AU-2019287750-A1 (AU)
Title: Cyano quinoline amide compounds as HER2 inhibitors and methods of use
Inventor: GRAY NATHANAEL S
IPC: C07D239/94
Filed: 2019-06-14
Abstract: The application relates to a compound having Formula I which modulates the activity of HER2 and/or a mutant thereof, a pharmaceutical composition comprising the compound, and a method of treating or preventing a disease in which HER2 and/or a mutant thereof plays a role.
Patent AU-2019288293-A1 (AU)
Title: Compounding and non-rigid image registration for ultrasound speckle reduction
Inventor: TOYONAGA NOAH YUZO
IPC: A61B8/00
Filed: 2019-06-18
Abstract: This disclosure relates to ultrasound imaging with reduced speckle. Ultrasound imaging with frequency compounding and angle compounding is disclosed. Techniques are disclosed to make ultrasound imaging with frequency and angle compounding more robust. One such technique is non-rigid image registration to align ultrasound images for angle compounding. Another disclosed technique includes selecting a subset of ultrasound images for non-rigid ultrasound image registration.
Patent AU-2019322487-A1 (AU)
Title: Methods and compositions comprising tumor suppressor gene therapy and CD122/CD132 agonists for the treatment of cancer
Inventor: SOBOL ROBERT E
IPC: C07K14/47
Filed: 2019-03-19
Abstract: Provided herein are methods and compositions for treating cancer in an individual comprising administering to the individual an effective amount of at least one CD 122/CD 132 agonist, at least one immune checkpoint inhibitor and a viral composition comprising one or more viruses engineered to overexpress a tumor suppressor gene and/or an adenoviral death protein. Also provided herein are methods and compositions for treating cancer in an individual comprising administering to the individual an effective amount of at least one oncolytic viral composition and at least one CD122/CD132 agonist and at least one immune checkpoint inhibitor. Also provided herein are methods of enhancing anti-tumor efficacy by administering the agents described above in combination with other cancer therapies. In highly aggressive forms of cancer, known to be generally resistant to immune therapies, these treatments unexpectedly resulted in complete tumor remissions and curative outcomes.
Patent AU-2019324737-A1 (AU)
Title: Energy absorbing bollard assembly
Inventor: HOTCHKIN THOMAS LUKE
IPC: E01F15/00
Filed: 2019-08-23
Abstract: A bollard unit 3 includes (a) a low height elongate base (7) having an upper section (9) that is formed for easy pedestrian access across the base from one side to the other side of the unit, and (b) at least one bollard post (13) extending upwardly from the base and forming a vehicle barrier.
Patent AU-2019329884-A1 (AU)
Title: Combinations for treatment of NASH/NAFLD and related diseases
Inventor: ESLER WILLIAM PAUL
IPC: A61P35/00
Filed: 2019-08-28
Abstract: The combination of (S)-2-(5-((3-ethoxypyridin-2-yl)oxy)pyridin-3-yl)-N-(tetrahydrofuran-3-yl)pyrimidine-5-carboxamide or pharmaceutically acceptable salt thereof, and 4-(4-(1-Isopropyl-7-oxo-1,4,6,7-tetrahydrospiro[indazole-5,4'-piperidine]-1'-carbonyl)-6-methoxypyridin-2- yl)benzoic acid or pharmaceutically acceptable salt thereof, for treatment of diseases, including non-alcoholic steatohepatitis (NASH), in mammals are described herein.
Patent AU-2019356283-A1 (AU)
Title: Threaded joint
Inventor: KAWAI TAKAMASA
IPC: F16L15/04
Filed: 2019-06-13
Abstract: Provided is a threaded joint having excellent tensile strength. A threaded joint 1 according to the present invention is formed through connection of a pin 2 having, on the outer circumference at the leading end side of a first steel pipe, a male thread part provided with a first male thread portion and a second male thread portion with steps C therebetween, and a box 3 having, on the inner circumference at the leading end side of a second steel pipe, a female thread part provided with a first female thread portion and a second female thread portion with the steps C therebetween, the connection being made through engagement between the male thread part and the female thread part. A length L1 of a first thread row A, a length L2 of a second thread row B, a cross-sectional area P1 at an end section position 4, a cross-sectional area P2 at an end section position 5, a cross-sectional area B1 at an end section position 6, and a cross-sectional area B2 at an end section position 7 satisfy formula (1): (P2,B2)min≤P1/{L1/(L1+L2)} and formula (2): (P2,B2)min≤B1/{L2/(L1+L2)}, where (P2,B2)min represents the smaller value between P2 and B2.
Patent AU-2019360176-A1 (AU)
Title: Haptic actuators fabricated by roll to roll processing
Inventor: MARSH STEPHEN ALAN
IPC: G08B6/00
Filed: 2019-10-11
Abstract: Described is a micro-haptic actuator device that can be fabricated with roll-to-roll MEMS processing techniques. The device includes a first body having a first surface and a second, opposing surface, the body has a chamber defined by at least one interior wall, a piston member disposed in the chamber, physically spaced from the at least one interior wall of the chamber, the piston member having a first surface and a second opposing surface. A membrane layer is disposed over and attached to the first surface of the body, with a portion of the membrane attached to the first surface of the piston member. The device also includes a first electrode supported on a second surface the membrane, and a second body that supports a second electrode, with the second body attached to the second surface of the first body.
Patent AU-2019361728-A1 (AU)
Title: System and method for detecting and identifying power line carrier controlled devices within an irrigation system
Inventor: MOELLER MARK
IPC: A01G25/16
Filed: 2019-10-02
Abstract: The present invention provides a system and method for detecting and identifying power line carrier controlled devices within an irrigation system having a PLC BUS and a plurality of PLC powered devices. According to first preferred embodiment, the method preferably may include the steps of: initializing a controller; transmitted an identification signal onto the PLC BUS; receiving the transmitted identification signal by a first powered device in the transmission line; recording the signal strength of the received identification signal by the first powered device; reducing the level of the received identification signal by a given increment; receiving the transmitted identification signal by a second powered device in the transmission line; recording the signal strength of the received identification signal by the second powered device; reducing the level of the received identification signal by a given increment; receiving the transmitted identification signal at the controller; polling each powered device for the received strength of the identification signal at each device; creating a lookup table and assigning a system ID number to each powered device based on the reported signal levels received by each device; and sending communications signals to the first powered device based on the system assigned ID number indicated in the lookup table.
Patent AU-2019400059-A1 (AU)
Title: Beverage preparation machine with capsule recognition
Inventor: GUYON BERTRAND
IPC: A47J31/44
Filed: 2019-12-10
Abstract: A machine (1) for preparing and dispensing a beverage (2) has: a capsule extraction unit (10) having a first part (11) and a second part (12) that are relatively movable between a distant position for inserting a capsule (3) and a close position for extracting such capsule (3); a control unit (40) for controlling the extraction unit (10) to extract such capsule (3); an outlet (20) for dispensing said beverage (2) formed by extracting such capsule (3) to a user-receptacle (4) located in a receptacle placing area; and a capsule recognition arrangement (30) connected to the control unit (40) for recognizing the colour of at least part of a capsule inserted in the machine (1).
Patent AU-2019468559-A1 (AU)
Title: A unique method of harnessing energy from the magnetic domains found in ferromagnetic and paramagnetic materials
Inventor: HOLCOMB ROBERT RAY
IPC: H02N11/00
Filed: 2019-10-04
Abstract: The present disclosure relates to a power generator and method of generating AC or DC power, including the removal of reverse torque and utilizing the electromagnetic coils of a generator stator to harvest the inherent energy available in the magnetic domains of ferromagnetic and paramagnetic materials of pole pieces of a generator rotor. The method comprises: determining an excitation cycle based on a target frequency of the power generator; executing the excitation cycle by providing a current to one or more wires of the generator according to a predefined sequence to align magnetic domains of the salient pole pieces of the generator rotor to produce an evolving magnetic flux field; and routing a resultant current, generated by the magnetic flux field, to a power output. Systems and apparatuses disclosed herein comprise means for carrying out the same.
Patent AU-2020200256-A1 (AU)
Title: A three-component CRISPR/Cas complex system and uses thereof
Inventor: WANG HAOYI
IPC: C12N15/11
Filed: 2020-01-14
Abstract: The invention described herein provides compositions and reagents for assembling a tripartite complex at a specific location of a target DNA. The invention also provides methods for using the complex to, for example, label a specific genomic locus, to regulate the expression 5 of a target gene, or to create a gene regulatory network.
Patent AU-2020202178-A1 (AU)
Title: Lamp
Inventor: XIE QINGBO
IPC: F21V29/70
Filed: 2020-03-27
Abstract: The present disclosure relates to a lamp comprising a PCB board and an integrated heat 
dissipation device, wherein the PCB board is a double-sided PCB board on both sides of 
5 which are suitable for installing LED lamp beads, the PCB board has two heat dissipation 
edges arranged relatively to each other, the integrated heat dissipation device comprises a 
heat sink and two heat dissipation arms, wherein the heat dissipation arms and the heat sink 
are integrally formed with the medium, and the two heat dissipation arms are respectively 
fitted snugly with the two heat dissipation edges. The lamp provided by the present 
.0 disclosure is assembled with a double-sided PCB board and an integrated heat dissipation 
device to improve the integration degree of the PCB board and the heat sink.  
10
Patent AU-2020204520-A1 (AU)
Title: Isolated polynucleotides and polypeptides, and methods of using same for increasing plant yield and/or agricultural characteristics
Inventor: PANKRATOV ILYA
IPC: C12N15/29
Filed: 2020-07-07
Abstract: Provided are isolated polypeptides which are at least 80% homologous to SEQ ID NO: 474
643, 645-679, 681-755, 757-760, 4806-6390, 6395-6396, 6401-6895, 6897-7249, 7251-7685, 
7687-7693, 7695-7700, 7702-7708, 7710-7796, 7798-7816, 7818, 7820-7837, 7839-7840, 
7842-7861, 7863-8134, 8136-8163 or 8164, isolated polynucleotides which are at least 80% 
identical to SEQ ID NOs: 1-170, 172-267, 269-424, 426-473, 761-2486, 2489-2494, 2496-4803 
or 4804, nucleic acid constructs comprising same, transgenic cells expressing same, transgenic 
plants expressing same and method of using same for increasing yield, harvest index, abiotic 
stress tolerance, growth rate, biomass, vigor, oil content, photosynthetic capacity, seed yield, 
fiber yield, fiber quality, fiber length, and/or nitrogen use efficiency of a plant.
Patent AU-2020208842-A1 (AU)
Title: Systems, methods, and devices for three-dimensional imaging, measurement, and display of wounds and tissue specimens
Inventor: DACOSTA RALPH
IPC: G01B11/25
Filed: 2020-01-17
Abstract: The present disclosure provides methods, systems, and devices for coregistering imaging data to form three-dimensional superimposed images of a biological target such as a wound, a tumor, or a surgical bed. A three-dimensional map can be generated by projecting infrared radiation at a target area, receiving reflected infrared radiation, and measuring depth of the target area. A three-dimensional white light image can be created from a captured two-dimensional white light image and the three-dimensional map. A three-dimensional fluorescence image can be created from a captured two-dimensional fluorescence image and the three-dimensional map. The three-dimensional white light image and the three-dimensional fluorescence image can be aligned using one or more fiducial markers to form a three-dimensional superimposed image. The superimposed image can be used to track wound healing and to excise cancerous tissues, for example, breast tumors. Images can be in the form of videos.
Patent AU-2020250246-A1 (AU)
Title: Media service
Inventor: DIMARIA PETER C
IPC: G06F16/2457
Filed: 2020-10-08
Abstract: OF THE DISCLOSURE 
A machine may form all or part of a network-based system configured to 
provide media service to one or more user devices. The machine may be 
configured to define a station library within a larger collection of media files. In 
particular, the machine may access metadata that describes the media files 
included in the collection and access a seed that forms the basis on which the 
station library is to be defined. The machine may generate a list of media files 
from the metadata and based on the seed and enable a human editor to modify 
the machine-generated station set according to a human-contributed input to the 
station list. The machine may then modify the station set based on the submitted 
input and configure a media service to provide one or more user devices with a 
datastream that includes media files selected from the modified station list.
5/11 
,,301 
,311 
321, 
SUPERSET MACHINE
METADATA GENERATE COLLECTION MACHINE- STATION SET 
(E.G., WITH METADATA GENERATE 
EDITOR (E.G., WITH 
INPUT) EDITOR 
INPUT) 
PRESENT 
331 
140 
STATION SET EDITOR 
MODIFY 510 DEVICE 
DEFINE INPUT 142 
SUBMIT 
33011O 
""410 
SUBSET '"" 420 
PORTION PORTION 
INCLUDE 
(E.G., EXCLUSIVELY) 
520 DATASTREAM 
PROVIDE 
150 160, 
152 USER 162 USER 
DEVICE DEVICE 
FIG. 5
Patent AU-2020256348-A1 (AU)
Title: Novel sulfonimidoylpurinone compounds and derivatives for the treatment and prophylaxis of virus infection
Inventor: LIANG CHUNGEN
IPC: C07D473/24
Filed: 2020-10-14
Abstract: NOVEL SULFONIMIDOYLPURINONE COMPOUNDS AND DERIVATIVES 
FOR THE TREATMENT AND PROPHYLAXIS OF VIRUS INFECTION 
Abstract 
NH 2 
H 
R-3 N 
O=S N 
R R (I), 
The present invention relates to compounds of formula (I), wherein R, R 2 
and R3 are as described herein, and their prodrugs or pharmaceutically acceptable salt, 
enantiomer or diastereomer thereof, and compositions including the compounds and 
methods of using the compounds.
Patent AU-2020264343-A1 (AU)
Title: Compositions and methods for treating cancer with anti-mesothelin immunotherapy
Inventor: ORENTAS RIMAS
IPC: C07K14/705
Filed: 2020-11-05
Abstract: Chimeric antigen receptors containing mesothelin antigen binding domains are 
disclosed. Nucleic acids, recombinant expression vectors, host cells, antigen binding 
5 fragments, and pharmaceutical compositions, relating to the chimeric antigen receptors 
are also disclosed. Methods of treating or preventing cancer in a subject, and methods 
of making chimeric antigen receptor T cells are also disclosed.
Patent AU-2020265898-A1 (AU)
Title: Immunosensor
Inventor: SCOBLE JUDITH
IPC: G01N33/542
Filed: 2020-04-30
Abstract: The present invention relates to methods for detecting analytes in a sample. The methods may also be used to determine the amount of analyte in the sample. The present invention also relates to antibody or antibody-like molecules and labelled antigens for use in these methods.
Patent AU-2020271496-A1 (AU)
Title: Cutting tool cleaning accessory
Inventor: JENSRUD ALLYN N
IPC: A61B90/70
Filed: 2020-03-30
Abstract: The present disclosure relates generally to the field of medical devices and medical device accessories. In particular, the present disclosure relates to a tool or accessory for cleaning a medical device. For example, the tool or accessory may clean a fluid delivery lumen of an endoscopic submucosal dissection (ESD) knife. The tool or accessory may include a housing with a first portion of an elongate member secured within a first portion of the housing and a second portion of the elongate member extending into a chamber of the housing.
Patent AU-2020274061-A1 (AU)
Title: Unidirectionally swinging linkage shutter, linkage shutter skylight roof, and shutter blades
Inventor: YANG DONGZUO
IPC: E06B7/086
Filed: 2020-04-01
Abstract: A unidirectionally swinging linkage shutter, a linkage shutter skylight roof, and shutter blades. The unidirectionally swinging linkage shutter comprises a frame (1) and shutter blades (2). The frame (1) comprises transverse frame parts (11) and longitudinal frame parts (12). Each longitudinal frame part (12) comprises a frame part body (121) and a fixing bar (122) protruding from the outdoor side of the frame part body (121) and provided with the same number of pin holes as the shutter blades. Two ends of the blade body (21) of each shutter blade are each provided with a swing axis end (216) and an outer swing end (217). A pin accommodating hole (22) is provided at the swing axis end (216). The outer wall of the swing axis end (216) is round and coaxial with the axis of the pin accommodating hole (22). Each shutter blade (2) is connected to the fixing bar (122) by means of a pin passing through the pin hole and the pin accommodating hole (22). A linkage connection part is provided on a rib (23) of the outer swing end (217). The linkage connection part is hinged with a linkage connection bar (3). The linkage shutter skylight roof comprises transverse roof beams (100) and longitudinal roof beams (200). Each longitudinal frame part (12) of the longitudinal roof beams (200) comprises a frame part body (121) and a fixing bar (122) protruding outward from the frame part body (121). The shutter blades (2) are connected to the fixing bars (122). The shutter blades do not interfere with each other, can be easily mounted and removed, and have a good sealing performance.
Patent AU-2020336337-A1 (AU)
Title: System and method for rapid genetic algorithm -based portfolio generation
Inventor: ALIAGA-DIAZ ROGER
IPC: G06N3/00
Filed: 2020-08-26
Abstract: Systems and methods for artificial intelligence-based computerized portfolio generation. For example, the genetic algorithm may be used to determine optimal portfolio allocations. In one embodiment, a method is disclosed. The method comprises receiving an electronic request for portfolio generation, the request comprising constraint data and risk tolerance data, retrieving performance and return data related to available investments, generating a set of portfolios based on the performance and return data, filtering the generated portfolios based on the received constraint data to determine a filtered set of portfolios. The method further comprises, for each of the filtered set of portfolios, calculating a plurality of returns for a portfolio using a genetic algorithm, and computing an expected utility score for each portfolio based on the received risk tolerance data. The method further comprises outputting investments associated with a portfolio having a highest expected utility score.
Patent AU-2020344553-A1 (AU)
Title: Compositions and methods for use in immunotherapy
Inventor: OAKES BENJAMIN
IPC: C12N15/113
Filed: 2020-09-09
Abstract: Provided herein are CasX:gNA systems, and compositions and methods relating thereto, the systems comprising CasX proteins, guide nucleic acids (gNAs), and optionally donor template nucleic acids useful for the modification cell genes encoding proteins involved in antigen processing, antigen presentation, antigen recognition, and/or antigen response, as well as methods of producing and using populations of cells comprising these modified genes. In some embodiments, the modified cells further express chimeric antigen receptors (CAR) or engineered T cell receptors (TCR). Such systems are useful for preparing cells for immunotherapy.