Patent SG-11201805496P-A (SG)
Title: An immunoassay for the diagnosis of viral infections
Inventor: STEINHAGEN KATJA
IPC: A61K39/12
Filed: 2017-02-22
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property -, Organization 111111110111101110101011111010111110111010111011111010111011111111101111011111 International Bureau 0.. .... .. ..... ..or::,„, (10) International Publication Number (43) International Publication Date WO 2017/144174 Al 31 August 2017 (31.08.2017) WIPO I PCT (51) International Patent Classification: (81) Designated States (unless otherwise indicated, for every G01N 33/569 (2006.01) C07K 14/08 (2006.01) kind of national protection available): AE, AG, AL, AM, A61K 39/12 (2006.01) AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, (21) International Application Number: DO, DZ, EC, EE, EG, ES, FL GB, GD, GE, GH, GM, GT, PCT/EP2017/000249 HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, (22) International Filing Date: KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, 22 February 2017 (22.02.2017) MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, (25) Filing Language: English RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, (26) Publication Language: English TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (30) Priority Data: 16000422.2 22 February 2016 (22.02.2016) EP (84) Designated States (unless otherwise indicated, for every 16000442.0 24 February 2016 (24.02.2016) EP kind of regional protection available): ARIPO (BW, GH, 16000454.5 25 February 2016 (25.02.2016) EP GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, 16000747.2 31 March 2016 (31.03.2016) EP TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, (71) Applicant: EUROIMMUN MEDIZINISCHE LABOR- DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, DIAGNOSTIKA AG [DE/DE]; Seekamp 31, 23560 LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, Lilbeck (DE). SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, (72) Inventors: STEINHAGEN, Katja; Kranichweg 1, 23627 GW, KM, ML, MR, NE, SN, TD, TG). GroB Gronau (DE). DEERBERG, Andrea; An der Milnze Published: 5, 23627 GroB Gronau (DE). LATTWEIN, Erik; — with international search report (Art. 21(3)) Kaninchenbergweg le, 23564 Lubeck (DE). RADZIM- Buchenweg 83, 23858 Reinfeld — with sequence listing of description (Rule 5.2(a)) SKI, Christiane; (DE). part BOTHFUR, Jana; Waschpauhl 3, 19217 Schlagsdorf (DE). 1-1 7r IN Il 7r 7r 1-1 (54) Title: AN IMMUNOASSAY FOR THE DIAGNOSIS OF VIRAL INFECTIONS I r ----- (57) : The present inventions relates to a polypeptide, preferably a dimer and/or hexamer thereof, more preferably a dimer, 1-1 C comprising a sequence selected from the group comprising SEQ ID N01, SEQ ID NO2, SEQ ID NO3, SEQ ID N04, SEQ ID N05, N SEQ ID N06, SEQ ID N07, SEQ ID N08, SEQ ID N019 and SEQ ID N09 or a variant thereof, preferably SEQ ID NO1 or a vari - O ant thereof, for the diagnosis of a disease, a diagnostically useful carrier comprising a means for specifically capturing an antibody to ,.f SEQ ID NO1 in a sample from a subject, a kit comprising the diagnostically useful carrier, and a method, preferably for diagnosing a disease, comprising the step detecting in a sample from a subject the presence or absence of an antibody to SEQ ID N01.