Patent EA-003273-B1 (EA)
Title: Bizoxime ether derivatives, methods and intermediate products for the production thereof, and their use for combating harmful fungi and pests
Inventor: BAYER HERBERT
IPC: C07C251/38
Filed: 1999-05-04
Abstract: 1. A bisoxime ether derivative of the formula I in which the variables have the following meanings: R<1> is halogen, C1-C4alkyl, C1-C4-haloalkyl, C1-C4alkoxy or C1-C4-haloalkoxy; n is 1 to 5, it being possible for the radicals R<1> to be different if n is other than 1; R<2> is C1-C4alkyl, C3-C6alkenyl or C3-C6alkynyl, it being possible for these groups to be partially or fully halogenated; Q is C(=CHOCH3)-COOCH3, C(=CHCH3)-COOCH3, C(=NOCH3)-COOCH3 or C(=NOCH3)-CONHCH3; and a salt thereof. 2. A process for the preparation of a compound of the formula I as claimed in claim 1, which comprises reacting a benzyl derivative of the formula II in which L<1> represents a nucleophilically exchangeable leaving group with a hydroxyimine of the formula III 3. A process for the preparation of a compound of the formula I as claimed in claim 1, which comprises reacting a benzyl derivative of the formula II as set forth in claim 2 with a dihydroxyimine of the formula IV to give a compound of the formula V and subsequently reacting V with a compound of the formula VI R<2>-L<2> (VI), in which L2 is a nucleophilically exchangeable leaving group to give a compound I. 4. A process for the preparation of a compound of the formula I as claimed in claim 1, which comprises reacting a benzyl derivative of the formula II as set forth in claim 2 with a carbonylhydroxyimine of the formula VII to give a compound of the formula VIII and subsequently reacting a compound of formula VIII either a) first with hydroxylamine or a salt thereof and then with a compound of the formula VI (R<2>-L<2>) as set forth in claim 3 or b) with a hydroxylamine or a hydroxylammonium salt of the formula IXa or IXb, where is the anion of an acid. 5. A composition against animal pests or harmful fungi, comprising customary additives and an effective amount of a compound of the formula I as claimed in claim 1. 6. A composition as claimed in claim 5 for controlling animal pests from the classes of the insects, arachnids or nematodes. 7. A method of controlling animal pests or harmful fungi, which comprises treating the pests or harmful fungi, their environment or the plants, areas, materials or spaces to be kept free from them with an effective amount of a compound of the formula I as claimed in claim 1. 8. The use of a compound of the formula I as claimed in claim 1 for the preparation of compositions against animal pests or harmful fungi. 9. A compound of the formula III as set forth in claim 2. 10. A compound of the formula IV as set forth in claim 3. 11. A compound of the formula VII as set forth in claim 4. 12. A compound of the formula VIIA as intermediate for the synthesis of compound I as claimed in claim 1 in which the variables have the meanings given in claim 1. 13. A compound of the formula VIII as set forth in claim 4. 14. A compound of the formula X as intermediate for the synthesis of compound I as claimed in claim1 where the variables have the meanings given in claim 1. 15. A compound of the formula XI as intermediate for the synthesis of compound I as claimed in claim 1 where the variables have the meanings given in claim 1. 16. A compound of the formula XIII as intermediate for the synthesis of compound I as claimed in claim 1 where the variables have the meanings given in claim 1. 17. A compound of the formula XV as intermediate for the synthesis of compound I as claimed in claim 1 where the variables have the meanings given in claim 1. 18. A compound of the formula XVI as intermediate for the synthesis of compound I as claimed in claim 1 where the variables have the meanings given in claim 1. 19. The use of a compound as claimed in any of claims 9 to 18 as intermediate for the synthesis of a compound I as claimed in claim 1.