baber/WOPTO huggingface dataset:
Patent LV-10120-A (LV)
Inventor: BRIGELIUS-FLOHE REGINA E
IPC: C12N15/00
Filed: 1992-11-13
Abstract: Plasmids with synthetic DNA sequences, which are suitable for expressing a precursor protein of rscu-PA (that is to say the unglycosylated protein portion of the single-chain prourokinase) in Enterobacteriaceae, especially E. coli, in an amount which is considerably above the yields which can be achieved using plasmids of the state of the art, are described. The plasmids according to the invention are characterised in that their operon has a controllable, optionally synthetic promoter, a Shine-Dalgarno sequence, a start codon, a synthetic structural gene and, downstream from the structural gene, at least one terminator. The preparation of the plasmids and of the synthetic DNA sequences starting from commercially available plasmids etc. is described. The precursor protein of rscu-PA which is expressed at a high rate using them can be refolded in a manner known per se to give the rscu-PA which can be employed therapeutically as plasminogen activator and which can then, if required, also be employed for cleavage, which is carried out in a manner known per se, to obtain the two-chain unglycosylated urokinase protein (rtcu-PA) on the industrial scale. <IMAGE>
Patent MD-960332-A (MD)
Title: Omeprazol compositions in the form of microgranules and process for production thereof
Inventor: LEDUC GERARD
IPC: A61K9/50
Filed: 1993-06-16
Abstract: The present invention relates to a stable formulation of omeprazole microgranules containing a neutral core consisting of sugar and starch, characterized in that it contains an active layer consisting of a dilution of omeprazole in mannitol in substantially equal amounts. It also relates to a process for producing such formulations.
Patent YU-163284-A (YU)
Title: Complex capacitive impedance
Inventor: DREIER B
IPC: H03H11/46
Filed: 1984-09-21
Abstract: A complex capacitive impedance (Z) whose capacitance value is considerably larger than the total capacitance of the components used in it is implemented by connecting a capacitive impedance (Z3) in series with a first resistor (R1) to form a voltage divider, and bypassing the first resistor (R1) with a voltage follower circuit (SFS).
Patent YU-42703-A (YU)
Title: Compounds specific to adenosine a1, a2a and a3 receptor and uses thereof
Inventor: CASTELHANO ARLINDO L
IPC: A61K/
Filed: 2001-11-30
Abstract: This invention pertains to compounds which specifically inhibit the adenosine A1, A2A, and A3 receptors and the use of these compounds to treat a disease associated with A1, A2A, and A3 adenosine receptors in a subjects, comprising administering to the subject a therapeutically effective amount of the compounds.
Patent AP-1167-A (AP)
Title: Anticonvulsant derivatives useful in treating amyotrophic lateral sclerosis (ALS).
Inventor: SHANK RICHARD P
IPC: A61K31/35
Filed: 1997-06-24
Granted: 2003-06-30
Abstract: Anticonvulsant derivatives useful in treating amyotrophic lateral sclerosis (als)are disclosed.
Patent AU-1055301-A (AU)
Title: Oxime o-ether compounds and fungicides for agricultural and horticultural use
Inventor: SANO HIROSHI
IPC: C07D213/53
Filed: 2000-11-02
Abstract: The present invention relates to novel oxime O-ether compounds represented by a general formula ÄIÜ; <CHEM> wherein R<1> represents C1-6 alkyl, C3-6 cycloalkyl, C1-6 alkoxy, etc., m represents an integer of 1 to 4, R<2> represents hydrogen atom, C1-6 alkyl, etc., R<3> and R<4> each independently represents hydrogen atom or C1-6 alkyl, etc., R<5> represents hydrogen atom, C1-6 alkyl, etc., R<6> represents C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, C1-6 alkoxy, Halogeno atom atom atom, etc. and n represents an integer of 1 to 4, and a fungicide for agricultural and horticultural use comprising the compound as the active ingredient.
Patent AU-1120688-A (AU)
Title: - 8-heterocyclo-ergoline derivatives useful in the treatment of extrapyramidal syndromes
IPC: C07D457/02
Filed: 1988-02-02
Abstract: Ergoline derivatives of the formula I <CHEM>  wherein R1 represents a hydrogen atom or a methyl group;      R2 represents a hydrogen atom or a methoxy group; R3 represents a hydrocarbon group having from 1 to 4 carbon atoms;  X represents a nitrogen atom and Y represents an oxygen atom, a - @-R4 or a -N=@-R5 group wherein R4 represents a hydrogen atom, a C1-C4 alkyl or a phenyl group, R5 represents a hydrogen atom, a C1-C4 alkyl, a phenyl, an amino or di(C1-C4 alkyl)amino group and the nitrogen atom of the group -N= @-R5 is not joined to the nitrogen atom represented by X, or Y represents a nitrogen atom and X represents an oxygen atom or a - @-R4 group wherein R4 is as above defined; and the pharmaceutically acceptable salt thereof; are useful for treatment of Parkinsonism and dyskinetic syndromes.
Patent AU-1130588-A (AU)
Title: Stabilized ace inhibitor compositions
Inventor: HARRIS MICHAEL
IPC: A61K9/20
Filed: 1988-02-04
Abstract: The cyclization, hydrolysis, and coloration of certain ACE inhibitors is minimized when they are formulated with a metal-containing stabilizer and a saccharide.
Patent AU-1143992-A (AU)
Title: Air-activatable polymerisable compositions
Inventor: KNEAFSEY BRENDAN
IPC: C08F2/00
Filed: 1992-03-05
Abstract: A one-part, air-activatable, polymerisable composition comprising:       (a) at least one free-radically polymerisable monomer, and (b) an activator system for effective polymerisation of the free-radically polymerisable monomer, said activator system comprising at least one auto-oxidisable compound of a formula which includes the structure I:- <CHEM> where x is 0 or 1, and where the lines representing unfilled valencies indicate bonds to carbon, hydrogen or hetero atoms, alone or in combination with a weak acid;  with the proviso that: when x = 0, the nitrogen atom in structure I is not bonded to a second nitrogen atom;  and when x = 1 there is a structure I in the compound in which the <CHEM>  moiety does not form part of a phenyl ring; with the proviso that the composition does not contain a peroxide, or a peroxide precursor which produces peroxide in the absence of air or any ingredient which is a significant source of radicals in the absence of air. Preferred auto-oxidisable compounds are selected from the group consisting of partially hydrogenated pyridines, condensation products of cyclic ketones and ureas, Schiff's bases, indoles, pyrroles, imidazoles, piperazines, carbazoles, tetrahydroquinolines, and substituted derivatives thereof, particularly dihydropyridines. The composition may also contain a soluble ionic salt, particularly a cobalt or iron salt. The compositions as described are stable on storage in the absence of air, are activated by exposure to air, and will then cure in either the presence or absence of air.
Patent AU-1295792-A (AU)
Title: A demodulator/modulator apparatus
Inventor: GILHOUSEN KLEIN S
IPC: H01S5/40
Filed: 1992-03-17
Abstract: A message communication system employing one or more centralized communication stations transferring messages through Earth orbit repeater satellites to or from mobile terminals with at least one central communication station having a first transceiver for transmitting a first communication signal to one or more mobile terminals and at least one mobile terminal having a second transceiver for receiving the first communication signal and demodulating it, and for transmitting at a predetermined duty cycle of the second transceiver, a second communication signal to at least one of the central communication stations. The preferred duty cycle over which the second communication signal is transmitted is about fifty percent of the second transceiver duty cycle. The communication system uses Time Division Multiplexed (TDM) communication signals using a number of channels as designated address channels with the remainder being used for data transfer. Information transmitted on the address channels is used by terminals to determine both the presence of a message and its corresponding data transmission or reception channel. In addition the terminals use the reception of the first communication signal to adjust return link transmission frequency to compensate for transmission path errors. The alternating duty cycle allows mobile terminals to use a single set of local oscillators for both transmission and reception modes of operation. To decrease interference with other systems the present system employs a power dispersal modulation function to achieve the footprint of a video signal for high transfer rate digital communication signals.
Patent AU-1297501-A (AU)
Title: Gasoline pump
Inventor: LITT ARYEH
IPC: B67D99/00
Filed: 2000-11-12
Abstract: In a gasoline pump system, means for concurrent filling of more than one car, tank or container with gasoline or other liquid petroleum products, comprising a display for guiding car drivers to a gasoline pump system having an outlet available for fueling, and a display for enabling each driver to identify the outlet used for filling his/her car, and to distinguish it from outlets used for filling other cars. A method for concurrent filling of more than one car, tank or container with gasoline or other liquid petroleum products, comprising the steps of:A. Guiding car drivers to a gasoline pump system having an outlet available for fueling; andB. Enabling each driver to identify the outlet used for filling his/her car, and to distinguish it from outlets used for filling other cars.
Patent AU-1568788-A (AU)
Title: Thermoplastic polyamide and polyetheresteramide-based powder compositions, a process for preparing them and their use for coating metal substrates
Inventor: MERVAL JEAN-PAUL
IPC: C08L77/12
Filed: 1988-05-06
Abstract: The invention relates to thermoplastic compositions in powder form based on polyamide and/or polyetheresteramide and containing resins obtained by polycondensation of aromatic sulphonamide compounds and of aldehydes or of dicarboxylic acids. The invention also relates to a number of processes for obtaining these powders and to their use for coating metal substrates without the need for any adhesion primer.
Patent AU-1599988-A (AU)
Title: Improved door frame structure
Inventor: HUELIN KIRK JOHN
IPC: E06B/
Filed: 1988-04-19
Abstract: PCT No. PCT/GB88/00299 Sec. 371 Date Aug. 3, 1989 Sec. 102(e) Date Aug. 3, 1989 PCT Filed Apr. 19, 1988 PCT Pub. No. WO88/08478 PCT Pub. Date Nov. 3, 1988.A sealable frame structure for a closable opening, such as a doorway, comprises a sub-frame (1) which is adapted to be built into an opening in a wall and a frame shroud (7) adapted to be fixed to the sub-frame. The sub-frame is U-shaped in cross-section and its web is provided with a series of holes (2) by means of which the sub-frame may be secured to the wall by anchor fixings. One limb (3) of the U-shaped frame is provided with a series of holes (4) for the reception of studs (8) welded on the frame shroud (7). A strip (9) of stainless steel or like material is secured to the other limb (5) of the subframe by means of bolts (10) and nuts (11) and the frame shroud (7) is secured to the strip (9) by screws (12) which engage in drilled and tapped holes (13) in a strip (14) of steel. An extruded strip (15) of silicone rubber having a protruding profile (16) is fitted over an edge of the strip (9) and forms a seal with the edge of a door closing the doorway. A door is also provided having a stepped edge portion extending along its upper and side edges for engagement with the sealable frame structure.
Patent AU-1719301-A (AU)
Title: Constructs for delivery of therapeutic agents to neuronal cells
Inventor: SHONE CLIFFORD CHARLES
IPC: A61P25/16
Filed: 2000-12-04
Abstract: A non-toxic polypeptide, for delivery of a therapeutic agent to a neuronal cell, comprises a binding domain that binds to the neuronal cell, and a translocation domain that translocates the therapeutic agent into the neuronal cell, wherein the translocation domain is not a HN domain of a clostridial toxin and is not a fragment or derivative of a HN domain of a clostridial toxin.
Patent AU-1773992-A (AU)
Title: Advanced reburning for reduction of nox emissions in combustion systems
IPC: B01D53/56
Filed: 1992-03-20
Abstract: Techniques for enhancing the burnout zone chemistry for NOx reduction are disclosed. The key parameters for the enhancement of burnout zone chemistry are: (a) a reaction temperature in the range from about 1300 DEG  F. to about 1900 DEG  F., and optimally in the range from 1400 DEG -1700 DEG  F.; (b) a carbon monoxide concentration below about 0.5 percent; and (c) the presence of nitrogenous reducing species. By controlling the stoichiometry associated with reburning to produce a slightly fuel-rich region for selective reducing agent injection, reductions can be achieved at relatively low temperatures which approach those obtained by conventional catalytic reduction.
Patent AU-1829795-A (AU)
Title: Method and apparatus for sputtering magnetic target materials
Inventor: MANLEY BARRY W
IPC: H01L21/203
Filed: 1994-10-21
Abstract: A sputtering magnet assembly generates a magnetic field having sufficient strength to produce a plasma-confining magnetic tunnel over the front surface of a magnetic target. A magnetic shunt positioned a spaced distance from the back surface of the magnetic target provides an alternate path for excess magnetic flux liberated by erosion of the target. The alternate path provided by the magnetic shunt has a lower magnetic resistance than most paths that exit the front surface of the target, pass into the sputtering region, and re-enter the front surface of the target. Accordingly, most of the excess magnetic flux is prevented from escaping into the sputtering region.
Patent AU-1960295-A (AU)
Title: Ocular tension depressant
Inventor: YOKOYAMA TOMIHISA
IPC: C07D403/10
Filed: 1995-03-16
Abstract: Use, in the manufacture of a medicament suitable for local application to the eyes for use in combination with a  beta -blocker for the treatment of ocular hypertension and/or glaucoma, of a compound of general formula (I): <CHEM>  wherein:   R<1> represents alkyl, alkenyl or a group of formula R<5>-A-B- (R<5> represents hydrogen, alkyl, cycloalkyl or aliphatic acyl, A represents oxygen or sulfur, and B represents a single bond or alkylene); R<2> represents alkyl, alkenyl or a group of formula -C(R<6>)(R<7>)(R<8>) (R<6> represents hydroxyl or alkoxy, and R<7> and R<8> represent hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, aryl or aralkyl); R<3> represents carboxyl or a group of formula -CON(R<9>)(R<10>) (R<9> and R<10> represent hydrogen or alkyl optionally substituted by 1 to 3 substituents from Substituent group (I)); and optionally substituted by 1 to 3 substituents from Substituent group (I)); and   R<4> represents carboxyl, carboxycarbonyl or tetrazol-5-yl; substituent group (I): aryl, 5- or 6-membered heteroaromatic ring group, halogen, hydroxyl, alkoxy, carboxyl, alkoxycarbonyl, amino, aliphatic acylamide and aromatic acylamide.
Patent AU-2011592-A (AU)
Title: Amylin and possibly insulin containing composition for the treatment of anorexia and related states
IPC: A61K38/22
Filed: 1992-05-23
Abstract: PCT No. PCT/US92/04357 Sec. 371 Date Nov. 24, 1993 Sec. 102(e) Date Nov. 24, 1993 PCT Filed May 23, 1992 PCT Pub. No. WO92/20367 PCT Pub. Date Nov. 26, 1992Method for treatment of a patient suffering from anorexia or a related condition by administering amylin or an analogue thereof and/or to the patient in an amount sufficient to increase amylin and/or insulin levels in the plasma of the patient.
Patent AU-2178388-A (AU)
Title: Olefin polymerization
Inventor: BOGGS ELIZABETH ANN
IPC: C08F4/62
Filed: 1988-09-01
Abstract: Olefins are polymerized by a process which uses hydrogen to control the resultant polymer characteristics. Polymer density, in-situ comonomer production, and polymer short chain branching can be regulated by the use of a carbon monoxide reduced polymerization catalyst system.
Patent AU-2299288-A (AU)
Title: N-acylamino acid derivatives and their use
Inventor: MORISHIMA HAJIME
IPC: C07C317/00
Filed: 1988-09-29
Abstract: An N-acylamino acid derivative of the formula: <CHEM> wherein each of R<1>, R<2>, R<4> and R<6> is hydrogen, lower alkyl, cycloalkyl, cycloalkylalkyl, aryl, aralkyl or a monocyclic or bicyclic heterocyclic group containing from 1 to 4 hetero atoms; each of R<3> and R<5> is hydrogen or lower alkyl; A is -CH(OH)-(CH2)qR<7> wherein R<7> is hydrogen, lower alkyl, cycloalkyl, cyloalkylalkyl, aryl, aralkyl, a monocyclic or bicyclic heterocyclic group containing from 1 to 4 hetero atoms or -E-R<1><0> wherein E is -S(O)i- wherein i is 0, 1 or 2, oxygen, -NR<1><1>- wherein R<1><1> is hydrogen, lower alkyl, cycloalkyl, cycloalkylalkyl, aryl or aralkyl, or <CHEM> wherein each of R<1><2> and R<1><3> is hydrogen, lower alkyl, cycloalkyl, cycloalkylalkyl, aryl or aralkyl, and R<1><0> is hydrogen, lower alkyl, cycloalkyl, cycloalkylalkyl, aryl, aralkyl or a monocyclic or bicyclic heterocyclic group containing from 1 to 4 hetero atoms provided that when R<1><0> is hydrogen, i is 0, and q is an integer of from 0 to 5; or -CH2-CHR<8>-CO-R<9> wherein R<8> is hydrogen, lower alkyl, cycloalkyl, cycloalkylalkyl, aryl, aralkyl or a monocyclic or bicyclic heterocyclic group containig from 1 to 4 hetero atoms, and R<9> is hydroxyl, -OX wherein X is alkyl, aryl, lower alkoxycarbonyloxyalkyl or 1-phthalidyl, or -N(Y<1>)(Y<2>) wherein each of Y<1> and Y<2> is hydrogen, lower alkyl, aryl, aralkyl or cycloalkyl, or Y<1> and Y<2> form together with the adjacent nitrogen atom a 5- or 6-membered heterocyclic group which may contain a further hetero atom; m is 0, 1 or 2; and n is an integer of from 1 to 5, provided that when R<1> is hydrogen, m is 0; or a salt thereof, which is useful as hypotensive drugs.
Patent AU-2316688-A (AU)
Title: Antibodies to angiogenin: immunotherapeutic agents
Inventor: FETT JAMES W
IPC: C07K16/00
Filed: 1988-08-05
Abstract: An antibody (Ab) immunologically reactive with angiogenin is claimed. Also claimed is a method for inhibiting angiogenesis in mamma by admin. the Ab or a Fab or F(ab1)2 fragment of it. The Ab is raised to a fragment or deriv. of angiogenin. The angiogenesis is tumour angiogenesis.
Patent AU-2319697-A (AU)
Title: Use of aryl n-substituted carboxamides to kill tumors
Inventor: PERO RONALD W
IPC: A61K33/243
Filed: 1997-03-03
Abstract: The use of benzamide and nicotinamide analogs, in particular N-substituted benzamides and nicotinamides, other than benzamides with N-pyridinyl substitutions, as anti-inflammatory agents.
Patent AU-2472684-A (AU)
Title: Solidification accelerators for concrete mixes
IPC: C04B28/04
Filed: 1984-02-20
Abstract: The present invention relates to liquid accelerators for the setting of concrete mixtures. These accelerators have a long shelf life even in higher concentrations than the liquid accelerators known heretofore and, within the defined concentrations, produce no precipitation. The new accelerators are characterized by containing only potassium aluminate, potassium carbonate and potassium hydroxide in a defined range. They can be used in any known hydraulic binding agents, they shorten the set time of these binding agents, and they improve the compressive strength of the products made with them.
Patent AU-2584297-A (AU)
Title: Sigma-2 receptors as biomarkers of tumor cell proliferation
Inventor: MACH ROBERT H
IPC: G01N33/574
Filed: 1997-03-19
Abstract: PCT No. PCT/US97/04403 Sec. 371 Date Sep. 17, 1998 Sec. 102(e) Date Sep. 17, 1998 PCT Filed Mar. 19, 1997 PCT Pub. No. WO97/34892 PCT Pub. Date Sep. 25, 1997The invention provides detectably-labeled compounds of formula (I): wherein A, B, C, D, E, F, R, X, Y and Z have any of the meanings given in the specification, and their pharmaceutically acceptable salts, are useful in competitive assays to assay for the presence of  sigma 2 receptors. Also disclosed are pharmaceutical compositions containing such a compound of formula (I), methods for their use and intermediates useful for preparing such compounds of formula (I).
Patent AU-2595299-A (AU)
Title: Fungicidal 7-alkyl-triazolopyrimidines
Inventor: PFRENGLE WALDEMAR
IPC: A01N43/00
Filed: 1999-02-09
Abstract: A process and intermediates for the preparation of triazolopyrimidine compounds of formula I <CHEM> wherein R<1>, X, L<1>, L<2>, L<3>, L<4> and L<5> are as defined in the description, which comprises reacting alkyl 2-aryl-3-alkyl-3-oxopropionates of formula IV <CHEM> wherein R<1> and L<1>, L<2>, L<3>, L<4> and L<5> are as defined for formula I and R' represents an optionally substituted alkyl group,  a) with 2-amino-Ä1,3,4Ü-triazole, and treating the resulting 5-hydroxytriazolopyrimidines of formula I, wherein X represents a hydroxy group, with a halogenating agent, and b) optionally treating the resulting 5-hydroxytriazolopyrimidines with an alcohol or a thioalkohol in the presence of a base, or with a metal amide, a metal alkyl amide or a metal dialkylamide, or a metal cyanide.A process and intermediates for the preparation of triazolopyrimidine compounds of formula I <CHEM> wherein R<1>, X, L<1>, L<2>, L<3>, L<4> and L<5> are as defined in the description, which comprises reacting alkyl 2-aryl-3-alkyl-3-oxopropionates of formula IV <CHEM> wherein R<1> and L<1>, L<2>, L<3>, L<4> and L<5> are as defined for formula I and R' represents an optionally substituted alkyl group,  a) with 2-amino-Ä1,3,4Ü-triazole, and treating the resulting 5-hydroxytriazolopyrimidines of formula I, wherein X represents a hydroxy group, with a halogenating agent, and b) optionally treating the resulting 5-hydroxytriazolopyrimidines with an alcohol or a thioalkohol in the presence of a base, or with a metal amide, a metal alkyl amide or a metal dialkylamide, or a metal cyanide.
Patent AU-2721084-A (AU)
Title: Detergents containing sulphosuccinic esters and polymer
IPC: C11D3/37
Filed: 1984-04-24
Abstract: Certain polymers, notably hydroxyethyl and hydroxypropyl cellulose, hydroxypropyl guars, xanthan gums, and certain acrylic polymers, enhance the foam stability of liquid detergents based on dialkyl sulphosuccinates while simultaneously providing increased viscosity.
Patent AU-2755599-A (AU)
Title: Pattern generator with improved precision
Inventor: SANDSTROM TORBJORN
IPC: G02B26/00
Filed: 1999-03-02
Abstract: The present invention relates to an apparatus for creating a pattern on a workpiece sensitive to radiation, such as a photomask a display panel or a microoptical device. The apparatus comprises a source (602) for emitting electromagnetic radiation, a spatial modulator (601) having multitude of modulating elements (pixels), adapted to being illuminated by said radiation, and a projection system (604) creating an image of the modulator on the workpiece. It further comprises an electronic data processing and delivery system (607) receiving a digital description of the pattern to be written, extracting from it a sequence of partial patterns, converting said partial patterns to modulator signals, and feeding said signals to the modulator, a precision mechanical system (605) for moving said workpiece and/or projection system relative to each other and an electronic control system coordinating the movement of the workpiece, the feeding of the signals to the modulator and the intensity of the radiation, so that said pattern is stitched together from the partial images created by the sequence of partial patterns. According to the invention the drive signals can set a modulating element to a number of states larger than two. <IMAGE>
Patent AU-2787301-A (AU)
Title: Halogen containing polymer compounds containing modified zeolite stabilizers
Inventor: DETTERMAN ROBERT E
IPC: C08L27/06
Filed: 2001-01-11
Abstract: The present invention relates to a halogen containing polymer compound containing a modified zeolite stabilizer. The modified zeolite stabilizer has a small particle diameter, narrow particle size distribution and less than 10 weight percent water. The modified zeolite stabilizer is formed by shock annealing, coating or a combination of the two methods.