baber/WOPTO huggingface dataset:
Patent CY-1123369-T1 (CY)
Title: Συνθεσεις και μεθοδοι για τη ρυθμιση της εκφρασης της απολιποπρωτεϊνης (α)
Inventor: PRAKASH THAZHA P
IPC: C12N15/113
Filed: 2020-09-22
Abstract: Παρέχονται στο παρόν ολιγομερείς ενώσεις με συζευγμένες ομάδες που στοχεύουν την απολιποπρωτεΐνη (a) [apo(a)]. Σε ορισμένες εφαρμογές, οι ολιγομερείς ενώσεις που στοχεύουν την apo(a) είναι συζευγμένες με Ν-Ακετυλογαλακτοζαμίνη. Επίσης, αποκαλύπτονται στο παρόν συζευγμένες ολιγομερείς ενώσεις που στοχεύουν την apo(a) για χρήση στη μείωση της apo(a) για την αγωγή, πρόληψη, ή βελτίωση ασθενειών, διαταραχών ή παθήσεων που σχετίζονται με apo(a) ή/και Lp(a). Ορισμένες ασθένειες, διαταραχές ή παθήσεις που σχετίζονται με apo(a) ή/και Lp(a) περιλαμβάνουν φλεγμονώδεις, καρδιαγγειακές ή/και, μεταβολικές ασθένειες, διαταραχές ή παθήσεις. Οι συζευγμένες ολιγομερείς ενώσεις που αποκαλύπτονται στο παρόν μπορεί να χρησιμοποιηθούν για την αγωγή αυτών των ασθενειών, διαταραχών ή παθήσεων σε ένα άτομο που έχει ανάγκη αυτών.
Patent CY-1126031-T1 (CY)
Title: Συνθεσεις για καθαρισμο του παχεος εντερου και την αντιμετωπιση γαστρεντερικων διαταραχων
Inventor: CURRIE MARK G
IPC: A61K38/10
Filed: 2023-05-26
Abstract: Η παρούσα εφεύρεση παρέχει πεπτίδια και συνθέσεις οι οποίες είναι χρήσιμες για την αντιμετώπιση γαστρεντερικών διαταραχών ή για καθαρισμό του παχέος εντέρου. Η παρούσα εφεύρεση παρέχει επίσης συνθέσεις και μεθόδους αντιμετώπισης γαστρεντερικών διαταραχών και φαρμακευτικές συνθέσεις για επίτευξη αυτών. Σε ορισμένες υλοποιήσεις, αυτές οι φαρμακευτικές συνθέσεις περιλαμβάνουν στοματικές δοσολογικές μορφές.
Patent GR-900300124-T1 (GR)
Title: Device for assuring the continuity of passage between two successive road or rail vehicles
Inventor: WANNEROY ROLAND
IPC: B61D17/20
Filed: 1991-09-27
Abstract: Deformable floor permitting continuity of passage between two vehicles, characterised in that it consists of a zone (9) for movement back and forth, formed from a thick wall with an accordion shape, made from an elastomeric composition comprising at least one reinforcement layer (17) or (18) and being closely linked, by adhesive bonding, to transverse rigid bars, the mounting of which, at each of their ends on a longitudinal axle (13), supporting the load, permits the deflection, on either side of a mean position, of the said transverse rigid bars (10) about the axle (13) which is itself elastically supported by the frame (11) for fixing to the platform floors of each of the vehicles. 
<??>Application to communicating tunnels of road or rail vehicles. 
<IMAGE>
Patent GR-970300026-T1 (GR)
Title: Dna encoding a human neuropeptide y/peptide yy/pancreatic polypeptide receptor (y4) and uses thereof
Inventor: BARD JONATHAN A
IPC: A61K38/00
Filed: 1997-09-30
Abstract: This invention provides an isolated nucleic acid molecule encoding a human Y4 receptor, an isolated protein which is a human Y4 receptor, vectors comprising an isolated nucleic acid molecule encoding a human Y4 receptor, mammalian cells comprising such vectors, antibodies directed to the human Y4 receptor, nucleic acid probes useful for detecting nucleic acid encoding human Y4 receptor, antisense oligonucleotides complementary to any sequences of a nucleic acid molecule which encodes a human Y4 receptor, pharmaceutical compounds related to human Y4 receptors, and nonhuman transgenic animals which express DNA encoding a normal or a mutant human Y4 receptor. This invention further provides methods for determining ligand binding, detecting expression, drug screening, and treatment involving the human Y4 receptor.
Patent HR-P20090604-T1 (HR)
Title: Locking nail system for arthrodesis reconstruction in calcaneus fractures
Inventor: MUNOZ FELIPE LOPEZ-OLIVA
IPC: A61B17/68
Filed: 2009-11-10
Abstract: A locking nail system for arthrodesis reconstruction of calcaneus fractures that is comprised of a cylindrical nail (1), several cannulated calcaneus-talar screws (2), a guide (3), guide tubes, bit, depth gauge, cannulated screwdriver, diapason impactor, bit with limiter and reference guide-pin, the principal object of which is the reconstruction of severe comminuted fractures of the calcaneus in humans and fixation of this bone after reconstructing its principal form, to the talus, in order to attain arthrodesis or fusion with the latter.
Patent HR-P20110456-T1 (HR)
Inventor: AHMED MAHMOOD
IPC: C07D413/04
Filed: 2011-06-17
Abstract: Spoj formule (I), ili njegova farmaceutski prihvatljiva sol: naznačen time štojedan od R5 i R6 je vodik ili R2, a drugi je (a) A je fenil ili a 5 ili 6-eročlani heteroarilni prsten; R1 je vodik ili do tri supstituenta, koje se neovisno bira između halogena, C(1-4)alkila, C(1-4)alkoksi, trifluormetoksi, difluormetoksi, trifluormetila, cijano i izborno supstituiranih fenilnih ili izborno supstituiranih 5- ili 6-eročlanih heteroarilnih prstena; R2 je vodik ili do tri supstituenta, koje se neovisno bira između halogena, C(1-4)alkila, C(1-4)alkoksi, trifluormetoksi, difluormetoksi, trifluormetila i cijano; svakog od R3, R3', R4 i R4' se neovisno bira između vodika, halogena i metila; R7 je vodik ili halogen; X je izravna veza; m je 0-2; n je 0-4; ikada R1 je supstituirani fenil ili 5- ili 6-eročlani heteroarilni prsten, isti je supstituiran s do tri supstituenta, koje se neovisno bira između halogena, C(1-4)alkila, C(1-4)alkoksi, trifluormetoksi, difluormetoksi, trifluormetila i cijano. Patent sadrži još 4 patentna zahtjeva.
Patent SI-1284767-T1 (SI)
Title: Injection device
Inventor: BERGERON LUC
IPC: A61M5/00
Filed: 2001-05-14
Abstract: The invention provides an injection device comprising an open cavity, an injection needle projecting from the bottom of this cavity, a first leakproof compartment delimited by a first section of a mobile barrier, first devices for displacing the said first section of a mobile barrier to vary the volume of the compartment, at least one passage communicating between the said first leakproof compartment and the said cavity, a second leakproof compartment for a product to be injected, delimited by a second section of a mobile barrier, and second devices for displacing the said second section of a mobile barrier to vary the volume of the compartment. The said first and second leakproof compartments extend longitudinally within a tubular body. The cavity is located at one end of this tubular body, while the said first and second devices for displacing the said first and second sections of a mobile barrier are accessible at the other end of the said tubular body.
Patent SI-2906251-T1 (SI)
Title: Pyrrolobenzodiazepine-anti-cd22 antibody conjugates
Inventor: VAN BERKEL PATRICIUS HENDRIKUS CORNELIS
IPC: C07K16/00
Filed: 2013-10-11
Abstract: Conjugates of an isolated humanized, anti-CD22 antibody with PBD dimers.
Patent DE-3587633-T2 (DE)
Inventor: MOEREMANS MARC KAREL JULIA JOZ
IPC: G01N33/52
Filed: 1985-05-29
Granted: 1994-02-17
Abstract: A process for staining proteins and nucleic acids wherein the stain is a suspension of colloidal metal particles and the proteins and nucleic acids are visualized as a coloured signal localized at the binding site of the colloidal metal particles to the proteins or nucleic acids or quantitatively determined at this site following art-known spectrophotometric procedures.
Patent DE-3587747-T2 (DE)
Inventor: CASEY MICHAEL EDWARD
IPC: G01T1/20
Filed: 1985-11-27
Granted: 1994-05-05
Abstract: A two-dimensional photon position encoder system (10) and process which includes a detector (20) for enhancing the spatial resolution of the situs of the origin of incident photons of gamma rays. A plurality of scintillator material members (22) interact with the incident photons and produce a quantifiable number of photons which exit the scintillation material members. A tuned light guide (68) having a plurality of radiation barriers (92) of predetermined lengths define slots which are operatively associated with one of the scintillator material members. These slots (90) serve to enhance the predictability of the statistical distribution of photons along the length of the slotted light guide (68). A detector (20) detects the distribution of the photons at preselected locations along the length of the slotted light guide. In one embodiment, this detector (20) comprises a photomultiplier (70) which gathers information concerning the photoelectrons which are then counted. The statistical distribution of these photoelectrons is processed by an improved pattern recognition technique such that the positioning information can be determined.
Patent DE-3781682-T2 (DE)
Inventor: WILSON JAMES
IPC: A23K1/165
Filed: 1987-11-24
Granted: 1993-01-21
Abstract: A method for the promotion of growth, particularly in the young of the pig and other farm animals, comprises administering epidermal growth factor (EGF) and/or dexamethasone or a physiologically active derivative thereof. EGF is also of value for the manufacture of a medicament for use in veterinary and human medicine in effecting an increase in the level of iron in a patient's bloodstream. A composition comprising EGF and an iron-providing material is of value both for the animal husbandry and the medical use of EGF.
Patent DE-3851937-T2 (DE)
Inventor: PHILIPPE MICHEL
IPC: A61K8/891
Filed: 1988-11-03
Granted: 1995-03-09
Abstract: Unsaturated cycloaliphatic esters of macrolidic and lincosamidic antibiotics are employed in the treatment of acne.
Patent DE-3855006-T2 (DE)
Inventor: BHATTACHARYYA ALAK A
IPC: B01J23/76
Filed: 1988-11-23
Granted: 1996-09-12
Abstract: A process for the removal of sulfur oxides from a gas which comprises (a) contacting the sulfur oxide-containing gas with at least one of certain metal, oxygen-containing components, e.g., modified perovskite-type components, at conditions effective to associate at least a portion of the sulfur oxides with the component to reduce the amount of sulfur oxides in the gas; and (b) contacting the component containing associated sulfur oxides at conditions effective to reduce the amount of sulfur associated with the component.
Patent DE-3873693-T2 (DE)
Inventor: COOYMANS PETRUS ARMIN MICHIEL
IPC: B21D7/06
Filed: 1988-11-03
Granted: 1993-03-18
Abstract: An apparatus for the manufacturing of work pieces using pressure, such as bending, punching etc, said apparatus in principle compriving a surface (2), an adjustable carrier (3) regarding the surface, for a thereon affixed pressure device such as a hydraulic cylinder, said carrier (3) is adapted to be pivoted about an axis (A-A) parallel to said surface crossing the pressure axis (B-B) of the pressure device, whereby the pressure device can be placed at any desired angle in relation to the table, especially in a first position wherein the pressure line (B-B) is vertically to said surface, and in a second position wherein it runs parallel to it, such that the work pieces can be extended beyond the pivoting support within the working area of the pressure device.
Patent DE-3879703-T2 (DE)
Inventor: LOEOEF INGEMAR
IPC: B05D5/00
Filed: 1988-04-18
Granted: 1993-10-28
Abstract: PCT No. PCT/SE88/00198 Sec. 371 Date Nov. 16, 1989 Sec. 102(e) Date Nov. 16, 1989 PCT Filed Apr. 18, 1988 PCT Pub. No. WO88/08336 PCT Pub. Date Nov. 3, 1988.A powder sprayer for the powder coating of an object is provided with an annular charging channel (9) for electrostatic charging of the powder. The channel is defined by an inner, longitudinal rod (8) and an outer tube, (7), both being manufactured of electrically insulating material. The rod (8) is centered in the tube (7) by means of spacer and turbulence members (10) with vanes which are obliquely inclined or helically configurated in relation to the longitudinal direction of the sprayer. In order to improve the charging and blending of the powder, the turbulators (10) are arranged pair-wise after one another, each with a plurality of vanes which are distributed about the rod (8) so that through flow channels are formed between the vanes. The vanes in adjacent turbulators (10) are, in this instance, offset in the circumferential direction in relation to one another, so that the leading edges of the vanes in a downstream turbulator (10) lie in register with the through flow channels in an upstream turbulator (10).
Patent DE-3881603-T2 (DE)
Inventor: GREGORY PETER
IPC: B41M5/39
Filed: 1988-07-20
Granted: 1993-10-14
Abstract: A thermal transfer printing sheet, suitable for use in a thermal transfer printing process, comprising a substrate having a coating comprising a water-insoluble dye of the formula: <CHEM>  wherein  R represents the residue of an active methylene compound; X represents hydrogen, halogen or an optionally substituted alkyl, aryl or heteroaryl radical; Y represents cyano, nitro, alkanoyl, aroyl, alklsulphonyl, arylsulphonyl or a group of the formula -COOR<1> or -CONR<2>R<3> wherein R<1> represents a hydrocarbyl radical and each of R<2> and R<3>, independently, represents hydrogen or a hydrocarbyl radical; and E represents the residue of a coupling component.
Patent DE-3882015-T2 (DE)
Inventor: CASILLI NICOLA
IPC: G03C1/72
Filed: 1988-10-28
Granted: 1993-11-04
Abstract: A photochromatic composition contains at least two photochromatic compounds, defined by the general formula: <CHEM> wherein the various substituents from R1 to R7 and X are as defined in the specification. In such a mixture, at least one photochromatic compound is defined by the general formula, wherein R7 represents a hydrogen atom, and at least one further compound is also defined by the general formula, wherein R7 represents an -NR8 R9, with R8 and R9 having the meaning as defined in the text.
Patent DE-3882061-T2 (DE)
Inventor: TARRO GIULIO
IPC: A61K39/00
Filed: 1988-02-17
Granted: 1994-02-03
Abstract: A process for extracting, from human neoplastic material, antigenic protein complexes which are capable of inducing delayed hypersensitivity and specific blastization of lymphocytes and the lipoglycoproteins obtained by means of such technique, which are to be employed in the specific immunotherapy of tumoral diseases.
Patent DE-3884909-T2 (DE)
Inventor: KAATZ GARY F
IPC: H03D13/00
Filed: 1988-09-22
Granted: 1994-02-03
Abstract: For use in a radio synthesizer (110), a digital phase detector (118) indicates the phase error between a reference signal provided by a reference oscillator (117) and an output frequency signal (114) provided by a voltage controlled oscillator (112). The digital phase detector (118) includes four flip/flops (310, 312, 314 and 316) which receive the frequency signals (116 and 120) provided by the oscillators (117 and 112) to generate steering signals (126) which optimally indicate the phase error between the frequency signals (116 and 120) as well as providing optimal (maximum) frequency steering when a frequency difference between the frequency signals (116 and 120) exists. Responsive to the flip/flops, digital logic circuitry (306) is used to provide a non-integrated level-type indication when the frequency signals (116 and 120) are phase locked.
Patent DE-3889170-T2 (DE)
Inventor: KOBAYASHI HISATAKA
IPC: G01R5/16
Filed: 1988-08-22
Granted: 1994-08-04
Abstract: An instrument with crossed-coil type (8, 9) movable magnet which performs desired indication by A-D converting a signal in accordance with the state of an object under measurement and applying to the crossed coils the current corresponding to a digital value after A-D conversion, comprising an A-D converter (4) to which an input signal corresponding to the state of the object under measurement is sent after overlapping with a ripple (2), thereby enabling improvement in the resolution of pointer indication.
Patent TR-199800836-T2 (TR)
Inventor: BROWN FRANK EDWARD
IPC: B26B21/14
Filed: 1996-11-08
Abstract: Bir emniyetli tras makinesi için bir tras biçagi birimi, özellikle koltuk alti bölgeleri olmak üzere vücudun tras edilmesi için eniyilenmis sekil ve boyutlara sahiptir. Biçak birimi, dogru sekilli keskinlestirilmis bir kenari olan ince uzun bir biçaga ve bir deriye temas eden yüzeye sahiptir, bu yüzeyde, uzunluk genisligin 1-4 mislidir ve 60 mm'den tercihan 40-45 mm'den fazla degildir. Deriye temas eden yüzey en azindan, 450 mm2, tercihan 600-750 mm2 bir taban alanina, ve (i) %65'den daha düsük bir olmayan dairesellige, ve (ii) genisligin %30'u bir köse yariçapinda ve deri temas yüzeyi ile ayni uzunluk ve genislikte bir dikdörtgenin daireselligine sahiptir. Biçak kenarina dik bir düzlemde, deriye temas eden yüzey konvekstir ve 15-70 mm, tercihan 25 mm bir yariçapi olan zahiri bir sarici daire ile en azindan üç noktada temas yapacak biçimde sekillendirilmistir.Biçak kenarinin önü ve arkasindaki koruma ve baslik yüzeylerinin her biri en azindan 140 mm2'lik bir deri temas ... (DEVAMI VAR)
Patent TR-199900248-T2 (TR)
Inventor: STIENSTRA PIETER SIJBREN
IPC: C09D201/00
Filed: 1997-08-07
Abstract: WO-A-9505739'da açiklanan ikameli 1,4,2-oksathiazinler ve bunlarin mono ve di-oksidleri, çürümeyi önleyici boyalarin kendinden cilali olma özelliklerini artiracak katki maddesi olarak kullanilir. Katki maddesi, terkibin toplam kuru kitle agirligi esas alinarak, %0.5 - 9.9, tercihen %1-8, en çok tercihen %2-4 miktarinda kullanilir. Tercih edilen katki maddesi, 3-(3,4-diklorofenil)-5,6-dihidro-1,4,2-oksathiazin dioksiddir.
Patent DE-60000106-T2 (DE)
Inventor: KOGURE NAOCHIKA
IPC: B32B37/28
Filed: 2000-05-26
Granted: 2002-11-21
Abstract: Disclosed herein is a skin-bearing expansion-molded article of a thermoplastic resin, which is formed by holding a cylindrical multi-layer foamed parison comprising a foamed thermoplastic resin layer and thermoplastic polymer layers situated on both outer and inner sides of the foamed layer in a mold to compression-mold it, wherein the molded article has a skin formed of the outer-side polymer layer of the multi-layer foamed parison on the surface thereof, and on the inner side of the skin, a core formed by fusion-bonding at least a part of the inner-side polymer layer of the multi-layer foamed parison to each other and a foam formed of the foamed layer of the multi-layer foamed parison. <IMAGE>
Patent DE-60002491-T2 (DE)
Inventor: SHULL A
IPC: H04B1/04
Filed: 2000-07-13
Granted: 2003-11-20
Abstract: An artificial ramping waveform profile is applied to a burst transmission power amplifier in order to reduce transients. A profile source is supplied with a plurality of pre-determined artificial ramping profiles. At the beginning of the burst transmission ramping period, one of the artificial ramping profiles is selected and fed to the power amplifier. The selection of the artificial ramping profile is based at least in part on the first message symbol of the message to be burst transmitted. Preferably, each different possible first message symbol has its own unique corresponding artificial ramping profile, and the corresponding waveform is used to artificially ramp the power amplifier when that message symbol is the first message symbol. At the end of the ramping period, the inputs to the power amplifier are switched to the traditional signal source, such as the FIR filters, etc., for receipt of the message symbols. The transmitted signal is based then on the response of the power amplifier to the artificial ramping profile and the message symbols. The generation of transient adjacent channel power is significantly reduced by artificially ramping the power amplifier rather than allowing for natural ramping. By choosing the artificial ramping profile based on the first message symbol, the phase trajectory changes near the end of the ramping period may be significantly smoothed, thereby lessening the generation of undesired harmonic power levels.
Patent DE-60004331-T2 (DE)
Inventor: DOWNEY NICHOLAS
IPC: G10L17/02
Filed: 2000-02-25
Granted: 2005-05-25
Abstract: This invention relates to an improved method and apparatus for speaker recognition. In this invention, prior to comparing feature vectors derived from speech with a stored reference model the feature vectors are processed by applying a speaker dependent transform which matches the characteristics of a particular speaker's vocal tract. Features derived from speech which has very dissimilar characteristics to those of the speaker on which the transform is dependent may be severely distorted by the transform, whereas features from speech which has similar characteristics to those of the speaker on which the transform is dependent will be distorted far less.
Patent DE-60004518-T2 (DE)
Inventor: BEHZAD R
IPC: H03B5/36
Filed: 2000-04-12
Granted: 2004-06-24
Abstract: An integrated receiver with channel selection and image rejection is substantially implemented on a single CMOS integrated circuit. A receiver front end provides programable attenuation and a programable gain low noise amplifier. LC filters integrated onto the substrate in conjunction with image reject mixers provide image frequency rejection. Filter tuning and inductor Q compensation over temperature are performed on chip. Active filters utilize multitrack spiral inductors with shields to increase circuit Q. Frequency planning provides additional image rejection. Local oscillator signal generation methods on chip reduce distortion. A PLL generates needed out of band LO signals. Direct synthesis generates in band LO signals. PLL VCOs are centered automatically. A differential crystal oscillator provides a frequency reference. Differential signal transmission throughout the receiver is used. ESD protection is provided by a pad ring and ESD clamping structure. Shunts utilize a gate boosting at each pin to discharge ESD build up. An IF VGA utilizes distortion cancellation achieved with cross coupled differential pair amplifiers having their Vds dynamically modified in conjunction with current steering of the differential pairs sources.
Patent DE-60007091-T2 (DE)
Inventor: KUNTZ LUDWIG
IPC: G06F17/21
Filed: 2000-03-15
Granted: 2004-09-02
Abstract: In addition to functioning as a conventional printer, a printer system responds to triggering strings of characters within incoming pages of data by calling upon a meta-command interpreter to execute meta-commands such as "#if . . . #endif," "#for . . . #next," and "#mid . . . " embedded within templates containing data and print commands which describe families of documents or reports. The incoming pages can be stripped of their printer control codes and can be then used as rectangular arrays of characters which control the customization and reduction of the templates into one or more customized documents or reports containing data extracted from the incoming pages inserted at points marked by the "#mid" meta-command and similar meta-commands. A first template, with a "#startform" command, can cause the meta-command interpreter to process subsequent incoming pages against a designated template without the need for further triggering. The system provides global search and replace functions for all incoming pages as well as optional double-byte to single-byte conversion.
Patent DE-60007133-T2 (DE)
Inventor: BESSARD YVES
IPC: C07D213/50
Filed: 2000-07-17
Granted: 2004-09-09
Abstract: A five-step process for preparing 1-(6-methylpyridin-3-yl) -2-[(4-methylsulphonyl)phenyl] -ethanone of formula (I) described; characterized in that a) 4-(methylthio) benzyl alcohol is converted with hydrochloric acid into 4-(methylthio) benzyl chloride, b) 4-(methylthio) benzyl chloride is converted with an alkali metal cyanide into 4-(methylthio) phenylacetonitrile, c) 4-(methylthio) -phenylacetonitrile is condensed with a 6-methylnicotinic ester to give 3-[2- (4-methylthio) phenyl) -2-cyanoacetyl] (6-methyl) -pyridine, d) 3-[2-(4-methylthio) phenyl)-2-cyanoacetyl] (6-methyl) -pyridine is hydrolysed and decarboxylated under acidic conditions to give 3-[2-(4-methylthio) phenyl) acetyl] (6-methyl) pyridine and, e) 3-[2(4-(methylthio) phenyl) acetyl] (6-methyl) pyridine is oxidized to give the end product. The compound of formula (I) is an intermediate for preparing COX-2 inhibitors, pharmaceutically active compounds having analgesic and antiinflammatory action.