baber/WOPTO huggingface dataset:
Patent CA-2446394-C (CA)
Inventor: SUN YUKUN
IPC: A61K38/22
Filed: 2002-05-08
Granted: 2016-08-16
Abstract: The present invention relates to derivates of an insulinotropic peptide Exendin-4 and pharmaceutically acceptable salts produced thereof, which are useful for the treatment of type II diabetes. Exendin-4 has the chemical structure as shown below: His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-X-Glu-Glu-Glu-Ala-Val-Y-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-Z In which: X represents Arg, Leu or Ile, Y represents His, Arg or Lys and Z represents Arg-OH, -OH, -NH2 or Lys-OH. The derivates of this invention may be prepared by synthetic chemical means, and more easily, by the recombinant techniques, which makes it possible to commercial production.
Patent CA-2453792-C (CA)
Title: A gfci without bridge contacts and having means for automatically blocking a face opening of a protected receptacle when tripped
Inventor: GERMAIN FRANTZ
IPC: H01H71/00
Filed: 2003-12-19
Granted: 2012-05-29
Abstract: Located within a GFCI is a movable contact bearing arm which cooperates with at least one fixed contact. When the movable arm is moved up to allow the at least one contact on the arm to close with at least one fixed contact, the GFCI is in a conducting state and current flows from a source of electricity through the closed contacts to a load and to the contacts of a receptacle. When the movable arm is moved down to open the contacts, the GFCI is in a non-conducting state and current cannot flow from the source of electricity to either the load or the receptacle contacts. In this invention, the up and down movement of the movable contact bearing arm is harnessed to move a blocking member located within the housing of the GFCI to a first position to block at least one opening of the receptacle as the movable arm is moved down or to a second position to allow the prongs of a plug to enter the openings of the receptacle as the movable arm is moved up. The downward movement of the movable contact bearing arm occurs when the GFCI goes into a non-conducting state. Resetting the GFCI by pressing in and then releasing a reset button causes the movable contact bearing arm to move up to make contact with the at least one fixed contact. As the movable arm moves up, the blocking member moves to the first or non-blocking position to allow the prongs of a plug to freely enter the openings in the face of the receptacle. GFCI's normally have two separate sets of internally located contacts known as bridge contacts where one set is used to connect a load to the source of electricity and the second set is used to connect a user accessible load to the source of electricity. The bridge contacts provide isolation between the conductors to the load and the conductors to the contacts of the GFCI receptacle when the GFCI is in a non-conducting state. In the GFCI here disclosed, the blocking member prevents the prongs of a plug from entering the receptacle when the GFCI is in a non-conducting state and, therefore, the need for the bridge contacts is diminished.
Patent CA-2457801-C (CA)
Title: Souche de streptococcus thermophilus et son utilisation
Inventor: DE SIMONE CLAUDIO
IPC: A61P25/28
Filed: 2002-12-19
Granted: 2013-06-04
Abstract: L'invention se rapporte à une nouvelle souche de Streptococcus thermophilus ssp. salivarius (déposée le 4 décembre 2001 à la DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH, Braunschweig, Allemagne, numéro d'enregistrement DSM 14667) et à des compositions comestibles, à des médicaments et à des produits vétérinaires la contenant. L'invention concerne aussi l'utilisation particulièrement efficace de cette souche dans la prévention/le traitement de la stéatose hépatique et de la stéatose hépatique non alcoolique.
Patent CA-2461113-C (CA)
Inventor: COURTEMANCHE ALAIN
IPC: A01C23/00
Filed: 2004-03-15
Granted: 2009-02-10
Abstract: A liquid manure spreading tool bar for use on a manure spreader, wherein the manure spreader has a tank and a pump, and wherein the spreading tool bar has a supporting frame externally mounted onto the tank, a manure distributor mounted onto the supporting frame, a vertically extending telescopic conduit made of a rigid material, and at least one manure discharging pipes connected to a corresponding outlet of the manure distributor. The supporting frame is movable in an up and down position with respect to the tank. Each of the manure discharging pipes is made of a rigid material and is vertically movable together with the frame and the manure distributor. The telescopic conduit has one end connected to the manure distributor while the other end is connected to the pump so as to feed the manure pumped from the tank to the manure distributor. Inasmuch as the telescopic conduit and discharging pipes are not flexible, they cannot break.
Patent CA-2466114-C (CA)
Title: Continuous extraction of underground narrow-vein metal-bearing deposits by thermal rock fragmentation
Inventor: FECTEAU JEAN-MARIE
IPC: E21C37/16
Filed: 2004-05-03
Granted: 2012-03-20
Abstract: A method for extracting minerals from a narrow-vein deposit by thermal fragmentation is provided. The method includes locating the vein and determining the extent thereof to form the boundaries of a stope. Access to the stope is prepared by forming a panel having an upper drift and a lower drift. Equipment for thermal fragmentation, including a burner, is installed from the upper drift. The burner moves along the panel surface in a sweeping motion, while rock chips spalled from the rock panel surface are collected. Multiple panels for processing can be realised, with lower panels being processed before upper panels, by excavating a sub- level to separate the lower and upper panels.
Patent CA-2466413-C (CA)
Inventor: HOWLEY PAUL
IPC: A61K39/00
Filed: 2002-11-20
Granted: 2014-11-04
Abstract: The present invention relates to NS1 proteins or parts thereof of Flaviviruses, in particular of Dengue viruses useful for vaccination against said Flavivirus and against one or more other Flaviviruses. The invention further concerns the NS1 protein or parts thereof of one Dengue virus serotype, in particular serotype 2, useful for vaccination against Dengue viruses from all serotypes. The invention further concerns DNA comprising an expression cassette coding for a Flavivirus NS1 or parts thereof, vectors, comprising said DNA and vaccines containing or expressing a Flavivirus NS1.
Patent CA-2466482-C (CA)
Inventor: DUNNING TED E
IPC: G11B20/12
Filed: 2002-11-09
Granted: 2012-08-07
Abstract: Des fichiers sont divisés en parties et au moins certaines de ces parties sont transmises à un client au moyen d'une voie de communication. Au moins certaines de ces parties transmises sont cachées localement. Ceci permet une lecture en continu ultérieure dudit fichier, tout en utilisant moins de largeur de bande en transmettant la partie dudit fichier qui n'a pas été caché, et en associant des parties cachées aux parties transmises. Dans certains modes de réalisation, des fichiers peuvent être représentés à un niveau de qualité faible par un premier ensemble de données, et à un niveau de qualité élevé par des ensembles de données supplémentaires. Les ensembles de données sont cachés localement, de sorte que durant la lecture en continu ultérieure dudit fichier, le niveau de qualité de la lecture peut être améliorée par l'envoi d'ensembles de données supplémentaires au moyen d'une largeur de bande qui serait autrement spécialisée dans la transmission des ensembles de données cachés.
Patent CA-2467414-C (CA)
Inventor: ELDRIDGE MARK
IPC: G01F5/00
Filed: 2004-05-17
Granted: 2010-10-05
Abstract: Débitmètre de type à tube de Pitot comprenant une série d'ouvertures ménagées le long du corps d'une sonde et en contact avec un fluide en déplacement. La moyenne et la corrélation des multiples mesures qui en résultent donnent une image représentative du flot parcourant un conduit. Des corrections permettent de compenser les aberrations dues à la forme non circulaire du conduit ou à d'autres types d'irrégularités. Le descriptif de l'invention précise de quelle manière les mesures peuvent être effectuées à l'aide d'un appareil approprié.
Patent CA-2471185-C (CA)
Title: Subcutaneous self attaching injection port with integral moveable retention members
Inventor: CONLON SEAN P
IPC: A61M37/00
Filed: 2004-06-16
Granted: 2012-11-06
Abstract: A self attaching injection port has integral moveable fasteners which are moveable from a undeployed state to a deployed state engaging tissue. The fasteners may be disposed radially or tangentially, and rotated to pierce the fascia. The fasteners may be rigid or elastically deformable.
Patent CA-2476793-C (CA)
Inventor: COLLINS P MICHAEL
IPC: E04B2/70
Filed: 2003-04-17
Granted: 2011-08-02
Abstract: Une plaque ondulée (32) est fixée sur la paroi intérieure (12) d'un mur creux (10) pour définir un espacement déterminé (25) entre les parois intérieure et extérieure (12, 13) et empêcher l'excédent de mortier de s'accumuler (28) sur la paroi intérieure (12). La plaque ondulée (32) comporte une série de canaux, de sillons ou de rainures (34) dans lesquels un ancrage (24) se projette dans les goujons (16) de la paroi intérieure (12) pour fixer la paroi extérieure (13). La plaque ondulée (32) est installée avant la construction de la paroi extérieure (13) et définit un espacement ou un intervalle minimum (25) entre les parois (12, 13) en fonction de l'épaisseur de la plaque (32). La paroi extérieure (13) est construite au voisinage le plus immédiat de la face extérieure de la plaque ondulée (32). Les rainures ou les canaux (34) de la plaque ondulée (32) créent une chambre utile pour la circulation de la vapeur et de l'air. La plaque (32) élimine la liaison avec le mortier (22) et assure un conduit d'évacuation de l'air même pour les quantités minimales de vapeur qui peuvent exister dans la cavité (25).
Patent CA-2482009-C (CA)
Inventor: ZHU BIN
IPC: G06Q99/00
Filed: 2004-09-13
Granted: 2012-11-20
Abstract: A public licensing infrastructure (PLI) for a digital rights management (DRM) system is described. In an implementation, a method includes generating a formal license for content. The formal license includes a decryption key for decrypting the content and access rules for accessing the content. A plurality of license authorities is configured to provide a plurality of partial licenses. The plurality of partial licenses is combinable to form the formal license. Each license authority provides a respective partial license.
Patent CA-2482466-C (CA)
Inventor: HUFFMAN MARK
IPC: A61K31/5377
Filed: 2003-04-17
Granted: 2012-11-20
Abstract: La présente invention concerne un nouveau processus de préparation du 5-[[2(R)-[1(R)-[3,5-bis(trifluorométhyl)phényl]éthoxy]-3(S)-(4-fluorophényl)-4-morpholinyl]méthyl]-1,2-dihydro-3H-1,2,4-triazol-3-one. Ce composé convient comme antagoniste du récepteur (neurokinine-1) de substances P. Ce composé convient, en particulier, pour le traitement de troubles psychiatriques, de maladies inflammatoires et de vomissements, par exemple.
Patent CA-2487034-C (CA)
Inventor: REESE KARL S
IPC: A61B17/04
Filed: 2004-11-04
Granted: 2008-03-11
Abstract: A suture anchor is provided having a body with at least one suture-receiving channel that extends distally from a proximal end of the body. The suture- receiving channel can include a cavity formed in a distal-most end of the body, or it can terminate at a transversely-extending bore formed through the body. The suture anchor can also include a suture loop that is positioned within the suture-receiving channel and cavity or bore, and that includes a proximal portion that extends proximal of the proximal end of the body.
Patent CA-2489730-C (CA)
Title: Use of mglur5 antagonists for the treatment of gerd
Inventor: LEHMANN ANDERS
IPC: A61P1/04
Filed: 2003-06-19
Granted: 2011-11-22
Abstract: The present invention relates to the use of metabotropic glutamate receptor 5 antagonists for the inhibition of transient lower esophageal sphincter relaxations. A further aspects of the invention is directed to the use of metabotropic glutamate receptor 5 antagonists for the treatment of gastro, esophageal reflux disease, as well as for the treatment of regurgitation and asthma.
Patent CA-2493487-C (CA)
Inventor: KRAMER WERNER
IPC: C07K14/47
Filed: 2003-07-28
Granted: 2013-01-22
Abstract: The present disclosure relates to a method for isolating a 145 kDa intestinal protein using a photoreactive 2--azetidinone compound. Also disclosed are the resulting protein, which is able to bind cholesterol and/or cholesterol uptakers, complexes of the protein with specific photolabile compounds, pharmaceutical compositions and methods and uses of the proteins and complexes for treating obesity, arteriosclerosis, high blood pressure or heart failure.
Patent CA-2496811-C (CA)
Title: Procede de preparation de produits alimentaires a base de viande hachee provenant de poules de reforme
Inventor: CRIDER WILLIAM A III
IPC: A23L13/60
Filed: 2003-08-28
Granted: 2006-01-10
Abstract: Dans la présente invention, on prépare un produit alimentaire à base de viande hachée provenant de poules de réforme au moyen d'une désosseuse mécanique équipée d'un filtre et de commandes de la température et de la pression. La poule leghorn est produite de manière à ce que l'aspect et la texture de sa viande soient similaires à ceux du boeuf haché.
Patent CA-2500261-C (CA)
Title: Improved core material
Inventor: LAMERS PETER HUBERTUS
IPC: B29C70/08
Filed: 2003-09-29
Granted: 2012-04-17
Abstract: The present invention relates to a drapable core material suitable for use in closed mould systems, hand lay-up applications and/or spray-up applications, preferably having a compression-resistance of more than 30 % at 1 bar pressure, wherein core material is based on at least one fibrous web containing a foam-structure within the web, said foam-structure being formed of a plurality of members, which members are separated from each other by channels which channels are permeable to resin. The invention further relates to a laminate comprising such core material, a method for manufacturing the core material and a method for manufacturing such laminate.
Patent CA-2500638-C (CA)
Title: Dispensing intermediate layers
Inventor: HEDEGAARD JENS
IPC: B65B41/12
Filed: 2003-10-01
Granted: 2011-05-10
Abstract: When stacking stackable items in layers on pallets, intermediate layers of paper/cardboard/film are often used for preventing loss of the items during transport. Even though the intermediate layers ensure to a large extent that items do not fall off the pallet, it cannot be entirely prevented that some of the stacked items fall off because the stacked items slid on the intermediate layers. Special intermediate layers are known, having a surface coated with non-skid coating which highly counteracts the unwanted sliding of the items in the layers stacked on a pallet. However, the laying of intermediate layers with non-skid surfaces constitutes a problem as the individual pieces of non-skid coated intermediate layer will adhere to each other. Thus, there is provided a method and a sheet dispenser where pieces of intermediate layers are successively dispensed, and where these layers are coated with a non skid coating during dispensing.
Patent CA-2503611-C (CA)
Inventor: MATHUR CHANDAN
IPC: G06F9/30
Filed: 2003-10-31
Granted: 2013-06-18
Abstract: A peer-vector machine includes a host processor and a hardwired pipeline accelerator. The host processor executes a program, and, in response to the program, generates host data, and the pipeline accelerator generates pipeline data from the host data. Alternatively, the pipeline accelerator generates the pipeline data, and the host processor generates the host data from the pipeline data. Because the peer-vector machine includes both a processor and a pipeline accelerator, it can often process data more efficiently than a machine that includes only processors or only accelerators. For example, one can design the peer-vector machine so that the host processor performs decision-making and non-mathematically intensive operations and the accelerator performs non-decision-making and mathematically intensive operations. By shifting the mathematically intensive operations to the accelerator, the peer-vector machine often can, for a given clock frequency, process data at a speed that surpasses the speed at which a processor-only machine can process the data.
Patent CA-2515142-C (CA)
Title: Hydraulic system for a slide
Inventor: FERNANDEZ LUIS
IPC: B29C45/33
Filed: 2004-02-02
Granted: 2009-04-28
Abstract: The invention relates to a form tool for injection-molding molded articles (6), especially PET parisons. The form tool comprises a base plate (2) and a stripper plate (3) having a slide (4). A plurality of separable male mold cones (5, 5') is provided on the slide (4). For removing the parisons (6), the male mold cones (5, 5') are completely opened using a hydraulic drive (12) instead of an inclined drag element.
Patent CA-2515219-C (CA)
Title: Fine-grained martensitic stainless steel and method thereof
Inventor: BUCK ROBERT F
IPC: C22C38/42
Filed: 2004-02-06
Granted: 2014-06-17
Abstract: A martensitic alloy in which the ASTM grain size number is at least 5, including (wt. %) up to about 0.5% C, at least about 5% Cr, at least about 0.5% Ni, up to about 15% Co, up to about 8% Cu, up to about 8% Mn, up to about 4% Si, up to about 6% (Mo + W), up to about 1.5% Ti, up to about 3% V, up to about 0.5% Al, and at least about 40% Fe.
Patent CA-2515590-C (CA)
Title: Pten inhibitor or maxi-k channels opener
Inventor: HONG KI WHAN
IPC: A61K31/47
Filed: 2004-02-24
Granted: 2011-09-13
Abstract: The present invention is directed to a new PTEN opener or a new opener of a large conductance Ca2+- activated K+  channel (Maxi-K channel) which comprises as an active ingredient a tetrazolylalkoxy-dihydrocarbostyril compound of the formula (I):   (see formula (I) wherein R is cycloalkyl, A is lower alkylene, and the bond between 3- and 4-positions of the carbostyril nucleus is a single bond or a double bond, or a salt thereof. The PTEN  opener is useful as a medicament for promotion of the survival of normal cells, brain cells, heart cells, and skin, and further for inhibiting of Gram negative sepsis and cell migration and cell invasion due to inhibition of PTEN. It is further useful as a medicament for the treatment of neuronal disorders, for example, an anticonvulsant, a neuroprotecting agent, a medicament for treatment of regional cerebral edema and neurologic motor impairment, cognitive disorders, traumatic brain injury, Parkinson's disease, epilepsy, migraine, and Alzheimer's disease, etc.
Patent CA-2517678-C (CA)
Inventor: ROTH ELDON
IPC: A23L13/70
Filed: 2004-03-02
Granted: 2010-02-16
Abstract: A method for injecting or forcing an ammonia-based pH modifying material into the interior of a meat product to raise the pH at one or more points within the interior of the meat product preferably to a pH above approximately 6Ø The ammonia-based pH modifying material may comprise aqueous ammonia (ammonium hydroxide solution) or a gas including some ammonia gas fraction. The temperature of the meat product may be controlled to a temperature near or just below the initial freezing temperature of the meat product during the time that the pH modifying material is injected. pH decreasing materials maybe injected into the interior of the meat product either before or after injection the ammonia-based pH modifying material.
Patent CA-2518574-C (CA)
Title: Vanne de surpresseur
Inventor: STEELE JAMES R
IPC: F16K31/126
Filed: 2005-09-08
Granted: 2013-01-08
Abstract: Valve d'écoulement dotée d'une poignée de fermeture qui actionne un boîtier afin d'empêcher les refoulements, et d'une plate-forme servant à bloquer le passage d'écoulements à travers la valve d'écoulement, la plate-forme soutient la poignée de fermeture de manière à se pousser afin de permettre au fluide de s'écouler à travers la valve d'écoulement.
Patent CA-2520469-C (CA)
Title: Controlling instrument
Inventor: COISSAC BRUNO
IPC: G10H1/34
Filed: 2003-04-17
Granted: 2011-02-22
Abstract: The invention relates to a controlling instrument which enables a mobile user to trigger electronic, electrical, acoustic, visual and mechanical events. In the musical domain, said instrument enables two-handed playing which, depending on the variants, ranges over more or less five simultaneous octaves, with further modulation possibilities without the addition of a pedal or a mouthpiece. The inventive instrument also comprises, as main characteristics, a prehension bar (1) that can be flexible and digital controls (3) which are adjacently arranged thereon, said flexible bar (1) controlling a sensor (5). The inventive device is especially suitable for shows and industry.
Patent CA-2521267-C (CA)
Title: Cooled rf ablation needle
Inventor: PETERSON DARION
IPC: A61B18/14
Filed: 2005-09-27
Granted: 2014-07-08
Abstract: An ablation system includes an ablation electrode assembly operatively connectable to sources of electrosurgical energy and cooling fluid. The electrode assembly includes a hub defining a chamber therein; at least one electrically conductive ablation needle extending from the hub, the ablation needle including a distal end portion configured to penetrate tissue, said distal end portion being electrically and thermally conductive for establishing electric and thermal communication with the tissue; a heat sink operatively connected to the ablation needle, the heat sink being connected to the ablation needle to draw energy away from at least the distal end portion thereof, the heat sink including a proximal end extending into the chamber of the hub; and a conduit fluidly connected to the hub for delivering fluid into the chamber thereof from the source of fluid, wherein the fluid withdraws energy from the proximal end of the heat sink.
Patent CA-2531236-C (CA)
Title: Aiding of cognitive function
Inventor: VAN KLINKEN BERNARDUS JAN-WILLEM
IPC: A23L33/15
Filed: 2004-06-24
Granted: 2012-01-17
Abstract: The invention provides the use of a bioavailable iron compound and a bioavailable zinc compound in a weight ratio of at least 2:1, and at least one B vitamin, in the manufacture of an edible composition, for use in aiding the cognitive development or cognitive performance of humans having an age of up to 18 years.
Patent CA-2533749-C (CA)
Title: Piperidine compounds useful as malonyl-coa decarboxylase inhibitors
Inventor: CHENG JIE FEI
IPC: A61P9/00
Filed: 2004-07-28
Granted: 2012-07-10
Abstract: The present invention provides methods for the use of compounds as depicted by structure (I), pharmaceutical compositions containing the same, and methods for the prophylaxis, management and treatment of metabolic diseases and diseases modulated by MCID inhibition. The compounds disclosed in this invention are useful for the prophylaxis, management and treatment of diseases involving in malonyl-CoA regulated glucose/fatty acid metabolism pathway. In particular, these compounds and pharmaceutical composition containing the same are indicated in the prophylaxis, management and treatment of cardiovascular diseases, diabetes, cancer and obesity.