baber/WOPTO huggingface dataset:
Patent CA-3159653-A1 (CA)
Inventor: BLEAU JACINTE
IPC: A61F5/01
Filed: 2018-12-04
Abstract: A knee orthosis is provided. In described embodiments, the knee orthosis is designed to follow a natural movement of a wearer's knee along an asymmetric helicoidal axis of rotation. In some embodiments, the knee orthosis has hinges with shells having displacing geometric centers which do not coincide. In some embodiment, the knee orthosis is made of femoral and tibial hinges manufactured as single integral pieces. In some embodiments, the orthosis is configured to realign the wearer's knee in a frontal plane. Corresponding methods for designing and manufacturing a custom knee orthosis are also provided.
Patent CA-3160810-A1 (CA)
Inventor: WANG MEI
IPC: A61P35/00
Filed: 2020-12-23
Abstract: La présente invention concerne des anticorps anti-FGFR2b ou des fragments de liaison à l'antigène de ceux-ci, des polynucléotides isolés codant pour ceux-ci, des compositions pharmaceutiques les comprenant, et leurs utilisations.
Patent CA-3162671-A1 (CA)
Title: Compositions topiques comprenant des proteines et des polyphenols de pois
Inventor: ALONSO COHEN MIGUEL ANGEL
IPC: A61P15/02
Filed: 2020-12-21
Abstract: L'invention concerne des compositions topiques comprenant des protéines et des polyphénols de pois et leur utilisation pour le traitement de troubles locaux ou généralisés provoqués par une perméation accrue des barrières épithéliales naturelles. Lesdits troubles peuvent être d'origine bactérienne, virale, inflammatoire, allergique et/ou fongique, ou endogènes ou idiopathiques.
Patent CA-3164233-A1 (CA)
Title: Il-2 orthologs and methods of use
Inventor: PENAFLOR ASPURIA PAUL-JOSEPH
IPC: C07K14/55
Filed: 2020-12-11
Abstract: The present disclosure relates to hIL2 orthogonal ligands (IL2 orthologs) that specifically and selectively bind to the extracellular domain (ECD) a transmembrane polypeptide comprising of a modified hCD122 polypeptide. The binding of the hIL2 ortholog to the modified hCD122 polypeptide participates in the transduction pathway of intracellular signaling resulting in a biological activity of the native intracellular signaling patterns associated with hIL2 binding to either the intermediate or high affinity hIL2 receptor but which exhibits selectivity to an engineered cell expressing an hCD122 orthogonal receptor. The hIL2 orthologs of the present invention exhibit significantly reduced binding relative to their binding to the extracellular domain of wild type hCD122, either alone or when hCD122 is present in the form of an endogenous high or intermediate affinity hIL2 receptors.
Patent CA-3165574-A1 (CA)
Title: Tamper evident container
Inventor: GUIRGUIS SAMEH
IPC: B65D43/16
Filed: 2021-01-24
Abstract: A tamper evident container includes a cover with a first interlocking flange with a first tab for opening the container and a first extension joined to the first tab along a first frangible score line, a base with a second interlocking flange with a second tab for opening the container and a second extension joined to the second tab along a second frangible score line, a rim extending around a perimeter of the base, the rim having a flat portion connected to an outer wall, and a flange portion extending from the outer wall portion, wherein a position of the flat portion and the flange portion correspond to a sheet line, and wherein the first and second interlocking flanges, when securely fastened together, prevent access to the first and second tabs, and require more force to separate than to sever the first and second extensions along the frangible score lines.
Patent CA-3166813-A1 (CA)
Inventor: CHEW GREG
IPC: G06Q20/04
Filed: 2020-02-04
Abstract: The present invention relates to a system and a method for performing exchanges of digital data records among a plurality of distributed databases. More specifically, the present invention relates to a technology agnostic atomic swap system platform configured to perform atomic swap transactions of digital data records among a plurality of distributed ledger technology platforms.
Patent CA-3169550-A1 (CA)
Inventor: PECOT CHAD
IPC: A61P35/00
Filed: 2021-04-07
Abstract: L'invention concerne l'inhibition de l'expression de séquences mutantes de KRAS au moyen de l'interférence par l'ARN.
Patent CA-3172981-A1 (CA)
Title: Method for treatment of neurological disorders using synaptic pathway training
Inventor: RUSTICK JOSEPH
IPC: A61P25/00
Filed: 2021-03-16
Abstract: Disclosed are methods of treating depression, mania, post-traumatic stress disorder (PTSD), and various other neurologic conditions using synaptic pathway training. Methods of synaptic pathway training include, generally, achieving a favorable treatment result by activating a synaptic pathway using a pharmacologic agent, such as treating refractory symptoms of depression with ketamine, following by potentiation of the favorable result by repeatedly stimulating the activated pathway. Stimulation of a synaptic pathway may be achieved by intrinsic means, such as performance of cognitive exercised, or extrinsic means, such as by delivery of a sensory stimulus to the patient, placing a potential voltage difference across the brain or a brain region, or by placing the brain or a brain region in a magnetic field.
Patent CA-3175860-A1 (CA)
Title: Cibles immunotherapeutiques dans le myelome multiple et procedes pour leur identification
Inventor: PERNA FABIANA
IPC: G01N33/68
Filed: 2021-03-26
Abstract: Selon l'invention, des protéines de surface principalement associées au myélome multiple sont identifiées en tant que cibles potentielles pour la mise au point d'agents thérapeutiques anti-myélome multiple. Selon un mode de réalisation, des anticorps, qui se lient spécifiquement à des épitopes des protéines identifiées qui sont associées à des cellules de myélome multiple, sont générés. Ces anticorps peuvent ensuite être utilisés pour cibler l'administration d'agents cytotoxiques à des cellules de myélome multiple chez un patient ou utilisés pour préparer des lymphocytes T CAR pour le traitement de patients atteints de myélome multiple.
Patent CA-3179439-A1 (CA)
Title: Systeme de reacteur de puits de forage universel et configurable
Inventor: PRESLEY GEOFFREY WARD
IPC: E21B43/24
Filed: 2021-05-21
Abstract: Un système de réacteur de puits de forage universel et configurable est conçu pour une régulation localisée de la chaleur, de la pression et de la réaction, afin de faciliter des conditions de réacteur souhaitées pour transformer des charges d'alimentation en produits valorisables par l'intermédiaire de processus et/ou de réactions à base de diluant. Le présent système fournit un réacteur de puits de forage universel pour la transformation par diluant, en produit(s) valorisable(s), d'une gamme diverse de charges d'alimentation, telles que des déchets d'hydrocarbures, des déchets municipaux, des déchets industriels et/ou des ressources riches en minéraux. La chaleur et la température à l'intérieur du réacteur de puits de forage sont régulées par la configuration de divers composants de réacteur afin de commander la direction et l'amplitude du transfert de chaleur interne et externe à l'intérieur dudit réacteur. Conjointement au transfert de chaleur à fréquence superficielle de la tuyauterie de réacteur ferromagnétique à des emplacements prédéterminés, la(les) température(s) et la(les) pression(s) requises pour les réactions ciblées et/ou les réactions de transformation souhaitées sont obtenues. Le système de réacteur de puits de forage universel comprend un ou plusieurs réacteurs de puits de forage ayant des caractéristiques configurables pour améliorer la dynamique du réacteur, les mécanismes de réaction et/ou la qualité du produit valorisable, pour faciliter une large gamme de réactions de transformation allant d'une approximation de la température ambiante jusqu'au-delà du point critique du diluant.
Patent CA-3182201-A1 (CA)
Title: Polyurethane composition having an adjustable pot life and suitable as a floor coating
Inventor: LEEDLE LINDA
IPC: C08G18/38
Filed: 2021-08-25
Abstract: The present invention relates to a polyurethane composition comprising a first component A and a second component B. The first component A comprises a polyol mixture P containing - at least one polyol P1 having an average molar mass of 800 to 30,000 g/mol, the polyol P1 being a polyhydroxy-functional fat and/or a polyhydroxy-functional oil, or a polyol obtained by chemical modification of natural fats and/or natural oils; and - preferably at least one polyol P2 selected from the group consisting of polyester polyols and polyether polyols. The second component B comprises at least one aliphatic polyisocyanate I, and the polyurethane composition additionally comprises at least one filler F. The polyurethane composition also comprises a tin catalyst K for the reaction of hydroxyl groups and isocyanate groups, which tin catalyst can form thio complexes, and at least one compound T which comprises at least one thiol group, wherein the molar ratio of all thiol groups of the at least one compound T to all metal atoms of the at least one tin catalyst K (T/K) lies between 2.2:1 and 40:1, and the molar ratio of all NCO groups of the polyurethane composition to all metal atoms of the at least one tin catalyst K (NCO/K) lies between 50 and 1500. The polyurethane composition is suitable for the formation of floor coatings and has, independently of the curing conditions, both a long pot life and a short curing time, which both can be adjusted if required.
Patent CA-3183523-A1 (CA)
Title: Determination de proximite
Inventor: TEN VELDHUIS MATTHEUS FRANCISCUS ALBERTUS
IPC: H04W4/80
Filed: 2021-07-02
Abstract: Un procédé de détermination de proximité comprend l'envoi d'un signal sans fil à partir d'une première étiquette mobile (120a) d'une pluralité d'étiquettes mobiles (120), le signal sans fil communiquant des informations d'identification associées à la première étiquette mobile (120a). Le signal sans fil est reçu au niveau d'une seconde étiquette mobile (120b) de la pluralité d'étiquettes mobiles (120), et des données de proximité comprenant les informations d'identification sont stockées dans une mémoire (127b) de la seconde étiquette mobile (120b). Les données de proximité sont envoyées à partir de la seconde étiquette mobile (120b) à un dispositif de communication mobile (110) à l'aide d'un premier protocole sans fil, sont reçues au niveau d'un dispositif de communication mobile (110), et sont stockées dans une mémoire (117) du dispositif de communication mobile (110). Les données de proximité sont envoyées du dispositif de communication mobile (110) à un serveur (130) à l'aide d'un second protocole sans fil, et les données de proximité sont stockées dans une mémoire (137) du serveur (130).
Patent CA-3186798-A1 (CA)
Title: Systems and methods for coupling prefabricated panels to structures
Inventor: DOMBOWSKY BRADEN LOUIS
IPC: E04F13/21
Filed: 2023-01-11
Abstract: Example embodiments provide systems and methods for coupling prefabricated panels to a structure. One example system provides a system for coupling a prefabricated panel to a structure. The system may comprise a first member. The first member may be couplable to a framing structure of the prefabricated panel. The system may also comprise a second member. The second member may pivot relative to the first member. The system may also comprise a fastener. The fastener may be configured to bias the first and second members together such that a component of the structure is at least partially receivable between the first and second members and tightening the fastener reduces a distance between the first and second members.
Patent CA-3188926-A1 (CA)
Inventor: CHABOT MARC-ANDRE
IPC: C13B25/06
Filed: 2023-02-08
Abstract: The present disclosure relates to a system and to a method for calibrating Brix in a liquid, sap, syrup or taffy. The system comprises: a tank for receiving a volume of the liquid; a temperature reading apparatus for measuring a temperature of the liquid; a weighing apparatus for measuring a weight of the volume of liquid received in the tank;  a volume measurement system for measuring the volume of the liquid received in the tank; an evaporator comprising a plurality of water injectors for spraying water, and a computer operatively connected to the apparatuses and using the data received from the same to calibrate the Brix in the liquid. The method comprises providing the Brix calibrating system;  measuring the Brix, temperature, weight, volume, and determining the Brix measurement based on the data received and using the computer to adjust the Brix by actioning the evaporator or the water injectors.
Patent CA-3191241-A1 (CA)
Inventor: COFLER MARIAN
Filed: 2013-11-14
Abstract: A printing technique is presented for efficiently printing (i.e. with production lines rates at high resolution and high accuracy) on outer surfaces of a plurality of objects passing in an optimized stream through a printing route/zone. According to this technique, at least one array of printing head units is provided being configured to define at least one printing route along a printing axis, where the at least one printing route is a substantially linear segment of a closed loop lane along which the objects are progressing.
Patent CA-3194684-A1 (CA)
Title: Content delivery routing with on-aircraft edge servers
Inventor: SLATER JOSHUA G
IPC: H04N7/173
Filed: 2020-10-06
Abstract: Methods, systems, and devices are described for providing media content items within a content delivery network including an edge tier of servers located on mobile platforms served by wireless communication links of a communication system and at least one terrestrial tier of servers. An example method may include receiving a request for an item from a device within a mobile platform served via a wireless communication link of the communication system and identifying a mobile edge server located on the mobile platform. The method may include redirecting the request to the mobile edge server if the item is stored on the mobile edge server. If not, the method may include determining whether the item is stored on a first terrestrial server of a first tier of servers. When the item is stored on the first terrestrial server, the method may redirect the request to the first terrestrial server.
Patent CA-3198300-A1 (CA)
Inventor: DECRESCENZO GARY A
IPC: A61K45/06
Filed: 2021-11-23
Abstract: The present disclosure provides methods of synthesizing a compound of Formula (P)-I. The method proceeds through several different pathways including several novel chiral separations, a Sonogashira coupling, a zinc mediated reductive cyanation, as well as through various halide containing intermediates. Also disclosed is the multi-kilogram preparation of several novel intermediates.
Patent CA-3203327-A1 (CA)
Inventor: LIN ZHIPENG
IPC: H04L5/00
Filed: 2021-12-20
Abstract: Embodiments of the present disclosure provide methods, apparatus, and computer program products for configured grant (CG) -based transmission. A method comprises: determining one or more synchronization signal and physical broadcast channel blocks (SSBs); determining one or more physical uplink shared channel (PUSCH) resources mapped to the determined one or more SSBs, according to mapping information on mappings between a set of SSBs and a set of PUSCH resources; and transmitting to a network node, data of the CG based transmission by utilizing the determined one or more PUSCH resources.
Patent CA-3206267-A1 (CA)
Inventor: SAVAGIAN LISA
IPC: C12Q1/6869
Filed: 2022-03-10
Abstract: Polypeptide nanopores synthetically functionalized with positively charged species, and methods of making and using the same, are provided herein. In some examples, a polypeptide nanopore includes a first side, a second side, a channel extending through the first and second sides, and a mutated amino acid residue. The mutated amino acid residue may be synthetically functionalized with a positively charged species that inhibits translocation of cations through the channel.
Patent CA-3211869-A1 (CA)
Title: Cheese analogue compositions
Inventor: ATAPATTU CHANDRANI
IPC: A23C20/02
Filed: 2022-03-14
Abstract: A cheese analogue (or substitute) composition includes a fat source, a starch source and/or a protein source, a leavening agent, and a water source. A method of making the cheese analogue (or substitute) composition includes mixing the fat source, the dry ingredient mixture, the leavening agent, and the water source to form a composition mixture, and heating the composition mixture to form curds.
Patent CA-3212750-A1 (CA)
Inventor: NARCY GABRIEL
IPC: F41G1/473
Filed: 2022-03-22
Abstract: The present invention relates to a method for assisting with firing on a moving target, comprising the steps of: (a) displaying, in a targeting window, superposed onto the direct view of a scene, a main indicator representing a firing axis of a firing system (14); (b) measuring a distance between the main indicator and a target in the scene; (c) determining the speed of movement of the target; (d) determining a targeting position, in the targeting window, anticipating an angular movement of the target in relation to the firing axis according to the speed of movement of the target, the speed of a projectile and the measured distance; and (e) displaying, in the targeting window, a secondary indicator at the determined targeting position.
Patent CA-3213716-A1 (CA)
Title: Arrangement de maintien de toile et dispositif de transfert de patient
Inventor: ANAGNOSTAKIS GEORGIOS
IPC: A61G7/10
Filed: 2022-03-29
Abstract: L'invention concerne un arrangement de maintien de toile (1) destiné à maintenir une toile (116) lors du transfert d'un patient placé sur la toile (116), comprenant au moins deux boutons (14) et au moins deux éléments de maintien (2). La toile (116) est maintenue entre les boutons (14) et les éléments de maintien (2) lorsqu'ils sont reliés l'un à l'autre, l'élément de maintien (2) est pourvu d'une ouverture (4) adaptée pour permettre l'insertion du bouton (14) à travers l'ouverture (4), l'arrangement de maintien de toile (1) peut être relié à un arrangement de traction (107), l'arrangement de maintien de toile (1) comprend un élément de liaison (17) pourvu d'au moins deux boutons et la tige (16) comprend une rainure circonférentielle (18) ayant une forme qui correspond à une section d'extrémité semi-circulaire (10) de l'élément de maintien (2), de sorte que la toile (116) est maintenue entre la rainure (18) et la section d'extrémité semi-circulaire (10) lorsque l'élément de maintien (2) est relié au bouton (18). L'avantage de l'invention est qu'un patient placé sur une toile peut être transféré d'une première surface à une surface de réception d'une manière facile et sûre.
Patent CA-3215989-A1 (CA)
Title: Conductive material dispersion, secondary battery electrode composition using same, electrode film, and secondary battery
Inventor: AOTANI YU
IPC: H01M4/1391
Filed: 2022-04-18
Abstract: Provided is a conductive material dispersion containing: a conductive material; a polymer including aliphatic hydrocarbon structural units and nitrile group-containing structural units; and a dispersion medium, the conductive material being at least one selected from a group consisting of carbon nanotubes and acetylene black.  The Mooney viscosity (ML1+4 at 100°C) of the polymer is 20-80 inclusive.  The aliphatic hydrocarbon structural units include alkylene structural units, and the content of the aliphatic hydrocarbon structural units relative to the mass of the polymer is at least 40 mass% but less than 85 mass%.  The content of the nitrile group-containing structural units relative to the mass of the polymer is 15-50 mass% inclusive.  The product (X×Y) of the complex elastic modulus X (Pa) and the phase angle Y (°) of the conductive material dispersion according to dynamic viscoelasticity measurement is 30-1,700 inclusive.
Patent CA-3216002-A1 (CA)
Inventor: WANG JIANCHENG
IPC: C07D207/34
Filed: 2022-04-19
Abstract: L'invention concerne un procédé de préparation d'un composé pyrrole amide, tel que représenté dans la formule (II). Le procédé de préparation comprend : la réaction d'un composé de formule (III) avec un composé de formule (IV) en présence d'un catalyseur au palladium et d'un ligand, X représentant Br ou I; R représentant H, D, F, Cl, Br, C1-4 alkyle, C1-4 alcoxyle, C1-4 haloalkyle, ou C1-4 haloalcoxyle; et PG1 représentant benzyle ou benzyle substitué.
Patent CA-3216675-A1 (CA)
Title: Method for automatically controlling a vehicle
Inventor: STAHLIN ULRICH
IPC: G05D1/02
Filed: 2022-03-16
Abstract: The invention relates to a method for automatically controlling a vehicle, wherein a driving specification is received from an external infrastructure, and in a normal operating mode the vehicle is controlled along a thus specified trajectory, and in a test mode the vehicle is controlled along a test trajectory which is different from the trajectory specified by the driving specification, and/or is controlled using test parameters. In this way it is possible to test the operational reliability of the infrastructure.
Patent CA-3221604-A1 (CA)
Title: Dispositif d'examen de la peau
Inventor: LIM KAR GAY
IPC: A61B5/00
Filed: 2022-08-24
Abstract: Un mode de réalisation d'un dispositif (10) pour l'examen d'un site cutané (18) est décrit. Dans un mode de réalisation, le dispositif cutané (10) comprend un boîtier (20), un moyen ou module d'éclairage (30) disposé à l'intérieur du boîtier, et utilisable pour émettre et disperser de la lumière. Le dispositif (10) comprend en outre un moyen ou module d'imagerie (40) disposé à l'intérieur du boîtier (20), une lentille du type lentille liquide (40a) agencée en association fonctionnelle avec le moyen ou module d'imagerie (40), et une lentille de correction de distorsion (60). Le dispositif (10) est configuré de telle sorte que, lors de l'utilisation, (i) la lumière est émise par le moyen ou module d'éclairage (30) pour projection sur le site cutané dans un trajet de lumière rayonnée (25) ; et (ii) la lumière est réfléchie depuis le site cutané (18) vers le moyen ou module d'imagerie (40) dans un trajet de lumière réfléchie (27). La lentille de correction de distorsion (60) est disposée dans le trajet de lumière réfléchie (27) entre le site cutané (18) et la lentille liquide (40a).
Patent CA-3221856-A1 (CA)
Inventor: LAFRANCE NORMAN
IPC: A61P9/10
Filed: 2022-06-10
Abstract: The present invention provides a closed loop generation and/or infusion system comprising a radionuclide generator, an activity detector, a controller, a dose calibrator, a pump, eluant source and an automated elution system controlled by software and hardware for generation and infusion of a radionuclide for administering a dose of generated radionuclide into a subject for diagnosing a peripheral arterial disease in a subject suffering from or suspected of suffering from peripheral arterial disease and/or metabolic disease via Positron Emitting Tomography (PET) or Single-photon emission computed tomography (SPECT) imaging technologies. More particularly, the present invention provides methods of determining whether a subject is suffering or at a risk of developing a peripheral arterial disease by performing quantitative assessment of blood flow in lower extremities or limbs of the subject; wherein the quantitative assessment is performed by analyzing one or more images and providing a severity score; and wherein the analysis of the one or more images is performed by using an automated system.