baber/WOPTO huggingface dataset:
Patent AU-2012308305-A1 (AU)
Title: Processes and kits to detect and monitor for diagnostic biomarkers for post traumatic stress disorder (PTSD) and to differentiate between suicidal and non-suicidal form of the disorder
Inventor: POLLARD HARVEY
IPC: G01N33/68
Filed: 2012-09-14
Abstract: Life-threatening traumas such as terrorist attacks, war, disasters, mental or physical assault, severe accidents and violence frequently provoke emotional and behavioral disturbances known as post-traumatic stress disorder (PTSD) and suicide related thereto. Accurate diagnosis and treatment planning for PTSD and suicide remain difficult. The discovery of specific markers creates new opportunities for more accurate clinical assessments identifying groups that may experience better outcomes when exposed to an intervention. The present invention provides a process of detection of P-11, UBE3A, STY1, EMAP-11, SIP1, ORC5L, DCX, SCYE protein in a biological sample of a subject suspected of suffering from PTSD and/or having suicidal tendencies, and provides additional PTSD markers which are specific to gender.
Patent AU-2012321245-A1 (AU)
Title: Closed loop charger for an implantable medical device system employing reflected impedance modulation
Inventor: OZAWA ROBERT
IPC: A61N1/378
Filed: 2012-09-27
Abstract: The disclosed system for providing closed loop charging between an external charger and an implantable medical device such as an IPG involves the use of reflected impedance modulation, i.e., by measuring at the external charger reflections arising from modulating the impedance of the charging coil in the IPG. During charging, the charging coil in the IPG is periodically pulsed to modulate its impedance. The magnitude of the change in the coil voltage produced at the external charger ΔV as a result of these pulses is assessed and is used by the controller circuitry in the external charger as indicative of the coupling between the external charger and the IPG. The external charger adjusts its output power (e.g., Icharge) in accordance with the magnitude of ΔV, thus achieving closed loop charging without the need of telemetering coupling parameters from the IPG.
Patent AU-2012332941-A1 (AU)
Title: Mechanical wound therapy for sub-atmospheric wound care system
Inventor: SHULER MICHAEL
IPC: A61M1/00
Filed: 2012-10-25
Abstract: A mechanical wound therapy (MWT) system includes a connection for a vacuum source, which is routed through an airtight covering to a porous material positioned over the wound. The porous material may be a tubing network interspaced by a netting material constructed of biologically inert or bioabsorbable material. Alternatively, the porous material may be a layered unified dressing in which layers of mesh, netting or thin perforated film are separated and fixedly attached to functional elements of the dressing (e.g., irrigation tubing) or spacers. The vacuum and irrigation systems may be completely separated. An airtight sealing layer or foldable adhesive sealing layer may seal the dressing and facilitate sealing the dressing to the wound margins. Additional modular devices such as a wound approximating system, positive pressure bladders and adjuvant therapy modules as well as enhanced monitoring technology can be added to synergistically increase the capabilities of each dressing.
Patent AU-2012336326-A1 (AU)
Title: Routing communications based on node availability
Inventor: NGUYEN VIET-HUNG
IPC: H04W84/18
Filed: 2012-01-30
Abstract: A node receives information that is to be transmitted to a destination. Upon receipt of the information, the node may query a busy device list to determine an availability of one or more neighbor nodes. The node may then identify a neighbor node that, according to the busy device list, is available to receive transmissions and is capable of propagating the information to the destination. The node may then transmit the information to the identified neighbor node.
Patent AU-2012340826-A1 (AU)
Title: Purification of anti-c-met antibodies
Inventor: PERSSON JOSEFINE
IPC: C07K16/00
Filed: 2012-11-20
Abstract: Provided herein are methods of purifying anti-c-met antibodies, compositions and pharmaceutical formulations comprising purified anti-c-met antibodies, and methods of using the same.
Patent AU-2012344189-A1 (AU)
Title: Guide and fastening device for plant support wires
Inventor: BORTOLUSSI CLAUDIO
IPC: A01G17/06
Filed: 2012-10-23
Abstract: Guide and fastening device for plant support wires, in particular for rows of grapevines, the device comprising at least one pair of vertical upright elements, fastened to a head pole (PT) and provided with longitudinal guides (2) within which are made to slide fastening elements (3) for the lateral containment wires (FC) for the growing vegetation. To each pair of upright elements (2) for the lateral containment wires (FC) is associated a further vertical upright (6) provided with a guide within which is made to slide a fastening element (7) for at least one carrying wire (FP).
Patent AU-2012348191-A1 (AU)
Title: Selectively moveable valve elements for aspiration and irrigation circuits
Inventor: OLIVEIRA MEL MATTHEW
IPC: A61M1/00
Filed: 2012-11-27
Abstract: Various arrangements of fluidics systems are disclosed. In one arrangement, an aspiration circuit for a fluidics system is disclosed that selectively controls aspiration. The aspiration circuit comprises an aspiration line operatively connected to a surgical instrument, an aspiration exhaust line operatively connected to a waste receptacle; an aspiration vent line connected at a first end to the aspiration line; and a selectively variable vent valve operatively connected to the aspiration vent line. The variable vent valve may be selectively moved to vary aspiration pressure within the aspiration line. Other fluidics systems are disclosed that include a selectively positionable irrigation valve that may also be incorporated into a fluidics system that includes a variable vent valve.
Patent AU-2012360048-A1 (AU)
Title: Method and device for fast dissolution of solid protein composition
Inventor: ILAN EREZ
IPC: B01F15/02
Filed: 2012-12-20
Abstract: Provided are methods and devices for dissolving solid protein compositions, such as solid compositions comprising fibrinogen, in an aqueous solvent. The methods comprise use of a closed container containing a volume of solid fibrinogen composition and a head space wherein the pressure within the headspace is sub-atmospheric. Aqueous solvent is introduced into the container while maintain the sub-atmospheric pressure, and subsequent to addition of the solvent, the size of the headspace is decreased to bring the pressure to atmospheric pressure. The devices are suitable for use in the disclosed method.
Patent AU-2012364670-A1 (AU)
Title: Formaldehyde-free lignin-amine coagulants
Inventor: DONG HONGCHEN
IPC: C08H7/00
Filed: 2012-12-20
Abstract: A method for making lignin-amines is provided. The method comprises providing a lignin; then modifying the lignin with modifier to create a modified lignin; and then reacting the modified lignin with an amine to form a lignin-amine. Suitable modifiers comprise acrylates. A method for coagulating suspended materials in a water stream is also disclosed. The method comprises providing a water stream and contacting the suspended materials in the water stream with at least one lignin-amine.
Patent WO-2013110121-A1 (WO)
Title: Dosage pour biomarqueur de trouble de système central nerveux
Inventor: BRILOT FABIENNE
IPC: A61K38/16
Filed: 2013-01-24
Abstract: La présente invention a trait à un procédé de diagnostic ou de détermination de trouble de système central nerveux (SNC). L'invention peut s'avérer utile également dans la prévision du risque de développement d'un trouble du SNC. L'invention concerne également l'identification d'un biomarqueur de trouble de SNC. Plus spécifiquement, la présente invention concerne l'identification d'un autoanticorps envers un récepteur de dopamine D2R chez un sujet comme un biomarqueur de trouble de SNC. Ladite invention a trait au traitement de trouble de SNC. Spécifiquement, ladite invention concerne le traitement d'un trouble auto-immunitaires de SNC tel que la chorée de Sydenham, le syndrome de Tourette ou l'encéphalite des noyaux gris centraux avec un antagoniste des anticorps du récepteur de dopamine D2R tel qu'un D2R soluble.
Patent WO-2014075132-A1 (WO)
Title: Mollusc spat growing system
Inventor: EDWARDS TIMOTHY JOHN MONRO
IPC: A01K80/00
Filed: 2013-11-13
Abstract: A mollusc spat growing system comprises a non-biodegradable bag or similar container formed of a mesh material, wherein the mesh size is from 0.1 mm x 0.1 mm up to 3.0 mm x 3.0 mm.
Patent AU-2013200538-A1 (AU)
Title: Agents and Methods Related to Reducing Resistance to Apoptosis-inducing Death Receptor Agonists
Inventor: ZHOU TONG
IPC: A61K38/00
Filed: 2013-02-01
Abstract: Provided herein is a method of reversing or preventing a target cell's resistance to a death receptor agonist. Also provided are methods of screening for biomarkers resistance of and monitoring resistance to death receptor agonists. Also provided are methods of selectively inducing apoptosis in a target cell, treating a subject with cancer, autoimmune or inflammatory diseases, comprising administering compositions provided herein. Further provided are compositions comprising agents that modulate CARD containing proteins. 02% MDA-231 3.9. UL-3C 10- i0 104, 10 PE Pr2 B ~TRAIL-R2--- >l 75- 75. so- 50. 6 25 - 25 2- TR-9 -T AS CO -*-2E12 -k2I -*-TRAIL _______ C Doses (nglml) 100- 100 > 75 75 = 25- 25 O -0-non-induced -0- non-induced -0-inced-9- induced TRA-8 (nglml)
Patent AU-2013200600-A1 (AU)
Title: Article of footwear
IPC: A43B7/06
Filed: 2013-02-05
Abstract: There is disclosed an article of footwear comprising: an upper for receiving a foot of a wearer, the upper including: an exterior layer that forms at least a portion of an exterior of the upper, the exterior layer including a plurality of incisions that extend through the exterior layer, and an interior layer located adjacent at least a portion of an inner surface of the exterior layer, the interior layer being exposed through at least a portion of the incisions; and a sole structure secured to the upper and having a polymer foam element with a connecting portion and a plurality of discrete sole elements extending downward from the connecting portion, the connecting portion being positioned adjacent the upper and the sole elements being separated by a plurality of sipes that extend upward into the sole structure, the sipes including: at least one sipe that extends in a direction of a longitudinal axis of the article of footwear, and a plurality of additional sipes that extend in a direction substantially perpendicular to the longitudinal axis, wherein the connecting portion has a first thickness in a forefoot region of the footwear, the connecting portion has a second thickness in a midfoot region of the footwear, and the connecting portion has a third thickness in a heel region of the footwear, the first and third thicknesses being less than the second thickness.
Patent AU-2013203213-A1 (AU)
Title: Method for treating stress urinary incontinence and symptomatic pelvic relaxation
Inventor: BROWN ROBERT C
IPC: A61B19/00
Filed: 2013-04-09
Abstract: The invention relates to a method, anchors, mesh, tools, and kits for surgical procedures. The anchors are implanted in soft-tissue. Once implanted, a surgeon can manipulate an implantable supportive mesh, particularly the tension, through the same incision that the anchors were implanted. The anchors permit micro-adjustments to the tension. The tension on the supportive mesh can be secured through the same incision.
Patent AU-2013204668-A1 (AU)
Title: Chimeric antigens for breaking host tolerance to foreign antigens
Inventor: GEORGE RAJAN
IPC: A61K38/095
Filed: 2013-04-12
Abstract: Disclosed herein are compositions and methods for eliciting immune responses against antigens. In particular, the compounds and methods elicit immune responses against foreign antigens that are otherwise recognized by the host as "self' antigens, thus breaking host tolerance to those antigens. Presenting the host immune system with a chimeric antigen comprising an immune response domain and a target binding domain, wherein the target binding domain comprises an antibody fragment, enhances the immune response against the foreign or tolerated antigen. Antigen presenting cells take up, process, and present the chimeric antigen, eliciting both a humoral and cellular immune response against the desired antigen.
Patent AU-2013206535-A1 (AU)
Title: Real-time casing detection using tilted and crossed antenna measurement
Inventor: BITTAR MICHAEL S
IPC: G01V3/30
Filed: 2013-06-25
Abstract: Methods and apparatus for detecting nearby conductors such as pipes, well casing, etc., from within a borehole. A nearby casing string can be detected by transmitting an electromagnetic signal from a transmit antenna on a downhole logging tool and measuring a parallel response signal with a first receive antenna parallel to the transmit antenna and a perpendicular response signal with a second receive antenna perpendicular to the transmit antenna, both receive antennas on the downhole logging tool. As the tool rotates, the transmitting and measuring are repeated to determine the azimuthal dependence of the parallel and perpendicular response signals. The azimuthal dependence is analyzed to determine a diagonal component of said azimuthal dependence for each response signal. Distance to a casing string can be estimated using the diagonal component of each response signal. At least one of the antennas is preferably tilted. FIG. 2A FIG. 2B FIG. 3A R2'O 210d H! gh Sidta '1 ~ \ ~Y),
Patent AU-2013213717-A1 (AU)
Title: Microparticles containing biodegradable polymer and cationic polysaccharide for use in immunogenic compositions
Inventor: O'HAGAN DEREK T
IPC: A61K9/16
Filed: 2013-08-08
Abstract: Immunogenic compositions are described herein which comprise microparticles that further comprise a biodegradable polymer. The microparticle compositions also comprise a cationic polysaccharide and an immunological species selected from an antigen, an immunological adjuvant and a combination thereof. Also described are methods of making such compositions and methods of administering such compositions. Methods of modulating the release rate of immunological species from microparticles are also described. These methods comprise varying the ratio of the cationic polysaccharide relative to the biodegradable polymer within the microparticles.
Patent AU-2013231122-A1 (AU)
Title: New Salts
Inventor: DE LA CRUZ MARILYN
IPC: A61K31/397
Filed: 2013-09-20
Abstract: I-IsVIitmnovenNRPonbl\DCC\RXS15539293_ .DOC-2WS9/20I3 This invention relates to a hydrochloride, malafe, oxalate and tartrate salt forms of 1-(4- (1 -[(E)-4-cyclohexyl-3 -trifluoromethyl-benzyloxyimino] -ethyl} -2 ethyl-benzyl)-azetidine-3-carboxylic acid (Compound I), to pharmaceutical compositions comprising this salt, to processes for forming this salt and to its use in medical treatment. In addition, the present invention also relates to new polymorphic forms of each of these salts, as well as to pharmaceutical compositions comprising these polymorphic forms, to processes for obtaining them, and their use in medical treatment.
Patent AU-2013234139-A1 (AU)
Title: Genes involved in noscapine production
Inventor: WINZER THILO
IPC: C12N15/82
Filed: 2013-03-12
Abstract: The disclosure relates to a nucleic acid molecule isolated from a
Patent AU-2013237703-A1 (AU)
Title: Use of cd83 in combination therapies
Inventor: NICOLETTE CHARLES
IPC: A01N37/18
Filed: 2013-10-03
Abstract: The present invention relates to improved methods of suppressing and/or preventing an undesired immune response comprising the use of CD83. In some embodiments, CD83 is coadministered to a subject with at least one other immunosuppressive compound. Method of the invention can be used to prevent or reduce the severity of autoimmune diseases and can also be used to induce tolerance to at least one therapeutic composition, such as a therapeutic protein or transplanted tissue.
Patent AU-2013241507-A1 (AU)
Title: Ophthalmic solution comprising diquafosol
Inventor: SAKATANI AKIKO
IPC: A61K47/04
Filed: 2013-03-25
Abstract: In a diquafosol eye drop containing a chelating agent at a concentration of 0.0001 to 1% (w/v), the production of insoluble precipitates during storage, which is usually observed in a diquafosol eye drop, and the deterioration in filtering performane during a production process (a filter sterilization process) can be prevented. In a diquafosol eye drop containing a chelating agent, the reduction in eye irritation and the improvement in preservative efficacy compared with those in a diquafosol eye drop that does not contain any chelating agent are observed. Therefore, in the present invention, stable physicochemical properties can be achieved during the course of production and distribution and during the course of storage by a patient, and the reduction in eye irritation and the improvement in preservative efficacy are observed. Particularly in a diquafosol eye drop containing a chelating agent, the deterioration in filtering performance during a production process (a filter sterilization process) is prevented. Therefore, highly efficient filter sterilization can be achieved during the course of production, which contributes to the reduction in production cost.
Patent AU-2013262078-A1 (AU)
Title: Pharmaceutical composition comprising (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano [3,4,b]indol]-4-amine and an anticonvulsant
Inventor: FROSCH STEFANIE
IPC: A61K31/55
Filed: 2013-05-16
Abstract: The invention relates to a pharmaceutical composition comprising a first pharmacologically active ingredient selected from (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano[3,4,b]indol]-4-amine and the physiologically acceptable salts thereof, and a second pharmacologically active ingredient which is an anticonvulsant selected from the group consisting of retigabin, lamotrigine, lacosamide, levetiracetam, carbamazepine, sultiame, phenacemide, felbamate, topiramate, pheneturide, brivaracetam, selectracetam, zonisamide, stiripentol, beclamide, mexiletin, ralfinamide, methyl- phenobarbital, phenobarbital, primidone, barbexaclone, metharbital, ethotoin, phenytoin, amino(diphenylhydantoin) valeric acid, mephenytoin, fosphenytoin, paramethadione, trimethadione, ethadione, ethosuximide, phensuximide, mesuximide, clonazepam, lorazepam, diazepam, clobazam, oxcarbazepine, eslicarbazepine, rufinamide, valproic acid, valpromide, aminobutyric acid, progabide, tiagabine, and the physiologically acceptable salts thereof.
Patent AU-2013265466-A1 (AU)
Title: Method and apparatus for stamping articles
Inventor: GUSTAV THORSTEN
IPC: A23G1/26
Filed: 2013-05-15
Abstract: The invention relates to a method for stamping a plurality of articles (2), the method comprising the steps of transporting the plurality of articles (2) along a first conveyance path (4), splitting a transport flow of the plurality of articles (2) along the first conveyance path {4} into at least two parallel transport lines so as to transport the plurality of articles (2) along at least two parallel second conveyance paths (8, 10), stamping the plurality of articles (2) transported along the at least two parallel second conveyance paths (8, 10) using at least two parallel stamping units (12, 14) and merging transport flows of the plurality of articles (2) along the at least two parallel second conveyance paths (8, 10) so as to transport the plurality of articles (2) along a third conveyance path (18). Further, the invention relates to an apparatus for stamping a plurality of articles (2), the apparatus comprising a transport unit configured to transport the plurality of articles (2) along a first conveyance path (4), a splitting unit (6) configured to split a transport flow of the plurality of articles (2) along the first conveyance path (4) into at least two parallel transport lines so as to transport the plurality of articles (2) along at least two parallel second conveyance paths (8, 10), at least two parallel stamping units (12, 14) configured to stamp the plurality of articles (2) transported along the at least two parallel second conveyance paths (8, 10) and a merging unit (16) configured to merge transport flows of the plurality of articles (2) along the at least two parallel second conveyance paths (8, 10) so as to transport the plurality of articles (2) along a third conveyance path (18).
Patent AU-2013270443-A1 (AU)
Title: Method and apparatus for monitoring cardio-pulmonary health
Inventor: SCHINDHELM KLAUS HENRY
IPC: A61B5/103
Filed: 2013-05-30
Abstract: Disclosed is a cardio-pulmonary health monitoring apparatus. The apparatus comprises a contactless motion sensor configured to generate one or more movement signals representing bodily movement of a patient during a monitoring session; a processor; and a memory storing program instructions configured to cause the processor to carry out a method of processing the one or more movement signals. The method comprises extracting one or more sleep disordered breathing features from the one or more movement signals, and predicting whether a clinical event is likely to occur during a predetermined prediction horizon based on the one or more sleep disordered breathing features.
Patent AU-2013270979-A1 (AU)
Title: Imidazo-oxadiazole and imidazo-thiadiazole derivatives
Inventor: QUATTROPANI ANNA
IPC: C07D513/04
Filed: 2013-05-23
Abstract: The present invention provides compounds of Formula (I) used as Amyloid beta lowering agent for the treatment of neurodegenerative diseases.
Patent AU-2013274734-A1 (AU)
Title: Methods and systems for non-physical attribute management in reservoir simulation
Inventor: FLEMING GRAHAM CHRISTOPHER
IPC: G06G7/48
Filed: 2013-05-28
Abstract: A disclosed method for a hydrocarbon production system includes collecting production system data. The method also includes performing a simulation based on the collected data, a fluid model, and a fully-coupled set of equations. The method also includes expediting convergence of a solution for the simulation by reducing occurrences of non-physical attributes during the simulation. The method also includes storing control parameters determined for the solution for use with the production system.
Patent AU-2013279083-A1 (AU)
Title: Balun
Inventor: NGUYEN MARK CHRISTOPHER
IPC: H01P5/10
Filed: 2013-06-17
Abstract: There is disclosed a balun for dividing an input electrical signal to produce first and second output electrical signals which are substantially out of phase, the balun including: an input port for receiving the input electrical signal; an input line for coupling the input electrical signal to a slotline; and an output line for coupling the first and second output electrical signals to, respectively a first output port and a second output port, the output line having a junction with the slotline; wherein the slotline couples the input electrical signal to the junction, and the junction acts as a divider to produce the first and second electrical signals;in which at least one of the input line, slotline and output line has a width and a length wherein the width varies over the length.
Patent AU-2013279748-A1 (AU)
Title: Conjugate of a photosensitiser and chitosan and uses thereof
Inventor: BERG KRISTIAN
IPC: A61P35/00
Filed: 2013-05-14
Abstract: The present invention relates to novel chitosan-based conjugates, e.g. nanocarriers, comprising a derivative of the biocompatible polymer chitosan conjugated to a photosensitising agent, and uses thereof in photochemical internalisation (PCI) and photodynamic therapy (PDT). The invention also relates to the use of the novel conjugates of the invention in treatment or prevention of diseases, particularly cancer, and for vaccination purposes.