baber/WOPTO huggingface dataset:
Patent NZ-547956-A (NZ)
Title: Substituted 8'-pyri(mi)dinyl-dihydrospiro-[cycloalkylamine]-pyrimido[1,2-a]]pyrimidin-6-one derivatives
Inventor: CHEREZE NATHALIE
IPC: A61K31/505
Filed: 2004-12-17
Abstract: Disclosed are dihydrospiro-[cycloalkylamine]-pyrimidone derivatives represented by formula (I) which are GSK3Beta inhibitors, wherein: X represents two hydrogen atoms, a sulfur atom, an oxygen atom or an alkyl group and a hydrogen atom; Y represents a bond, a carbonyl group, or an optionally substituted a methylene group; R1 represents an optionally substituted 2, 3 or 4-pyridine ring or a 2, 4 or 5-pyrimidine ring; R2 represents an optionally substituted benzene or naphthalene ring; R3 represents a hydrogen atom, an alkyl group or a halogen atom; R4 represents a hydrogen atom, an alkoxy carbonyl group, a cycloalkyl carbonyl group, a benzoyl group, or an alkyl group, the groups being by optionally substituted; o and m represent 1 to 2; n represents 0 to 3; p represents 0 to 2; and q represents 0 to 2; and wherein the remaining substituents are as defined herein. Also disclosed is the use of a compound as defined above for the preparation of a medicament for preventive and/or therapeutic treatment of a disease caused by abnormal GSK3  activity (such as neurodeqeneretive diseases selected from the group consisting of Alzheimer's disease, Parkinson's disease, tauopathies, vascular dementia, acute stroke, traumatic injuries, cerebrovascular accidents, brain cord trauma, spinal cord trauma, peripheral neuropathies, retinopathies or glaucoma).
Patent NZ-552692-A (NZ)
Title: Use of apoptosis-specific EIF-5A sirnas for the manufacture of a medicament for use in the treatment of a disease treatable by suppression of the JAK/STAT pathway.
Inventor: THOMPSON JOHN E
IPC: A61K31/713
Filed: 2005-07-20
Abstract: Disclosed is the use of an siRNA of an apoptosis specific eIF-5A in the manufacture of a medicament for use in the treatment of a condition treatable by suppression of the activation of the JAAK/STAT pathway, wherein said siRNA suppresses activation of the JAK/STAT pathway in a cell.
Patent NZ-554575-A (NZ)
Title: An apparatus and method for weathering of metal roof sheets used in roof construction
Inventor: WEE ROBERT
Filed: 2007-04-18
Abstract: An apparatus and method for weathering of metal roof sheets used in roof construction. Particularly applicable to roll-formed roofing sheets, the apparatus and method form a protrusion in each valley of a corrugated roof sheet along one end thereof, for the purpose of preventing water flow there through when the roof sheet has been installed. The weathering is achieved by using a suitably shaped stump assembly that impacts upon the end of the sheet causing it to bend upwards and rearwards.
Patent NZ-564715-A (NZ)
Title: Panel with rebate in end so that adjacent panels conceal post supporting adjacent panels
Inventor: WATTS FRED
IPC: E01F15/08
Filed: 2007-12-21
Abstract: Disclosed is a panel for assembling in conjunction with at least one supporting post, the panel consisting of a core layer with a cover layer having a fabric and resin. A rebate is formed along an edge, extending inwards such that a post can be concealed between adjacent panels when the panels are viewed face on.
Patent NZ-567356-A (NZ)
Title: Method for treating a liquefied natural gas stream obtained by cooling using a first refrigerating cycle and related installation
Inventor: PARADOWSKI HENRI
IPC: F25J1/02
Filed: 2006-10-11
Abstract: The disclosure concerns a method which consists in cooling the LNG stream (11) with a coolant (83) in a first heat exchanger (19). The coolant (83) is subjected to a second semi-open refrigerating cycle (21), independent of the first cycle (15). The method includes a step of introducing the under-cooled LNG stream (59) in a distillation column (49) and a step of recovering a gas stream (69) at the head of the column (49). The second refrigerating cycle (21) includes a step of forming a coolant stream (73) from part of the head gas stream (69), a step of compressing the coolant stream (73) up to a high pressure, then a step of expanding part (81) of the compressed coolant stream (75) to form an essentially liquid under-cooling stream (83). The essentially liquid stream (83) is evaporated in the first heat exchanger (19).
Patent NZ-574653-A (NZ)
Title: Solid dressing for treating wounded tissue
Inventor: MACPHEE MARTIN
IPC: A61F13/00
Filed: 2007-08-06
Abstract: Disclosed is a solid dressing for treating wounded tissue in a mammal comprising at least one haemostatic layer consisting essentially of a fibrinogen component and a fibrinogen activator (e.g., thrombin), wherein said haemostatic layer is formed by combining said fibrinogen component and fibrinogen activator in an aqueous solution at approximately 4 degrees celcius, reducing the temperature of said aqueous solution to form a frozen aqueous solution, and reducing the moisture content of said frozen aqueous solution to produce said haemostatic layer. Further disclosed is the use of said dressing for reducing the loss of blood and/or other fluid from wounded tissue in a mammal.
Patent NZ-574788-A (NZ)
Title: Improvements in and relating to ladder restraints
Inventor: SUTHERLAND DEREK WAYNE
IPC: E06C1/04
Filed: 2007-08-06
Abstract: A ladder restraint is disclosed which includes two arms, which are orientated, in use, to project away from a wall or roof. The arms are spaced apart to receive the legs of a ladder therebetween and a gate is attached to each arm. The gates are configured to allow unidirectional passage of the ladder legs toward or away from the wall or roof. (62) Divided Out of 548703
Patent NZ-575278-A (NZ)
Title: Process for the preparation of synthesis gas
Inventor: DOORN SIEBOLT
IPC: C01B3/38
Filed: 2007-09-07
Abstract: Disclosed is a process for the production of a vapour phase mixture 5 with a H2O/C molar ratio of at least 2 which comprises steam and at least one hydrocarbon or oxygenated hydrocarbon with an atmospheric boiling point in the range of -50 to 370 degrees C, wherein steam is introduced at the bottom of a distillation column and (oxygenated) hydrocarbon is introduced at the top of said distillation column and the steam is contacted with the (oxygenated) hydrocarbon in the distillation column. Also disclosed is a process that comprises the steps of a) preparing a vapour phase mixture comprising steam and at least one hydrocarbon or oxygenated hydrocarbon with an atmospheric boiling point in the range of -50 to 370 degrees C, said vapour phase mixture having a H2O/C molar ratio of at least 2, wherein the vapour phase mixture is prepared in a distillation column by feeding the (oxygenated) hydrocarbon at the top and steam at the bottom of the column and the steam is contacted with the (oxygenated) hydrocarbon in the distillation column, and b) catalytically or non-catalytically converting the vapour phase mixture into synthesis gas, wherein the oxygen is only added in bonded form, so that elemental oxygen is absent in the process. Further disclosed is synthesis gas, vapour phase mixture or methanol produced by the process.
Patent NZ-577338-A (NZ)
Title: Crystalline potassium salt of lipoxin a4 analogs
Inventor: SANDER MICHAEL
IPC: A61K31/192
Filed: 2007-12-04
Abstract: Disclosed are crystalline potassium salts of lipoxin A4 analogs represented by formula (I), wherein the crystalline potassium salt of formula (I) is an anhydrate, monohydrate, dehydrate or dehydrated form thereof, and wherein the compound of formula (I) is a single stereoisomer or any mixture of stereoisomers. A method for making the said potassium crystalline salts is also disclosed. Also disclosed is the use of the said potassium salts for the manufacture of a medicament, particularly for treating an inflammatory disease or autoimmune disorder.
Patent NZ-578412-A (NZ)
Title: Napadisylate salt of 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one as agonist of the beta 2 adrenergic receptor
Inventor: PUIG DURAN CARLOS
IPC: C07D215/26
Filed: 2008-02-08
Abstract: Disclosed is a crystalline mono-napadisylate and/or hemi-napadisylate salt of 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one and pharmaceutically acceptable solvates thereof. Also disclosed is the use of the said salt in the manufacture of a medicament for treating a pulmonary disease or condition in a mammal associated with beta-2 adrenergic receptor activity.
Patent NZ-585651-A (NZ)
Title: Server for compressing video according to connection speed and streaming to users
Inventor: PERLMAN STEPHEN G
IPC: H04W4/00
Filed: 2008-12-04
Abstract: A server centre (210) for hosting low-latency interactive audio/video communications comprising a plurality of servers (402) that run one or more applications and are operable to compute audio/video data in response to control inputs (406a, 406b) from a user and an inbound routing network that receives packet streams from users via a first network interface and routes the packets to one or more of the servers (402) wherein the packet streams include user control inputs (406a, 406b). The server centre (210) further includes a compression unit (404) coupled to receive the audio/video data from the one or more servers (402) and output compressed audio/video data and an output routing network that routes the compressed audio/video data to each of the users over a corresponding communication channel via a second interface. The compression unit (404) is operable to modify a compression rate in response to current characteristics of the corresponding communication channel for each user so as to optimise performance.
Patent NZ-585789-A (NZ)
Title: Pyrazine-2-carboxamide derivatives to treat diseases mediated by blockade of the epithelial sodium channel
Inventor: BHALAY GURDIP
IPC: C07D473/34
Filed: 2008-12-09
Abstract: The disclosure relates to pyrazine-2-carboxamide derivatives such as 3,5-diamino-6-chloro-pyrazine-2-carboxylic acid[8-[6-(3-isopropyl-ureido)-pyridine-3-carbonyl]-1,3,8-triaza-spiro[4 .5]dec-(2E)-ylidene]-amide represented by the structural formula shown herein. These compounds are suitable for the treatment of an inflammatory or allergic condition selected from cystic fibrosis, primary ciliary dyskinesia, chronic bronchitis, chronic obstructive pulmonary disease, asthma, respiratory tract infections, lung carcinoma, xerostomia, and keratoconjunctivitis sire.
Patent NZ-590650-A (NZ)
Title: Buprenorphine analogs
Inventor: KYLE DONALD J
IPC: A61K31/485
Filed: 2009-07-30
Abstract: Disclosed herein are Buprenorphine compounds of formula (I), (II) and (III), wherein the substituents are as defined within the specification, processes for their preparation, compositions comprising said compounds and uses thereof. Said compounds have useful activity as opioid receptor agonists and as such are useful in the treatment of pain.
Patent NZ-593562-A (NZ)
Title: Inductive charging system in which primary power source is stopped before secondary side charger
Inventor: TAKADA KAZUYOSHI
IPC: B60L11/18
Filed: 2009-12-24
Abstract: 593562 Disclosed is a resonance type non-contact charging device. The device is comprised of a power source (13), a primary-side resonant coil (11), a secondary-side resonant coil (21), a charger (24) receiving power from the secondary-side coil (21), a battery (25) connected to the charger (24) and a stop control unit (14, 27). The primary-side coil (11) receives electric power from the power source (13). The secondary-side resonant coil (21) is arranged apart from the primary-side resonant coil (11) in a non-contact manner and receives electric power from the primary side resonant coil (11) through magnetic field resonance between the primary-side resonant coil (11) and the secondary-side resonant coil (21). The stop control unit (14, 27) stops the power source (13) before the charger (24) is stopped when charging is to be stopped.
Patent NZ-594224-A (NZ)
Title: System and method for communicating power system information through a radio frequency device
Inventor: SCHWEITZER III EDMUND O
IPC: H04W52/02
Filed: 2007-05-18
Abstract: A method of communicating between a radio interface unit (400) and a portable terminal (102) is disclosed. The radio interface unit has a radio for communicating with the portable terminal by transmitting and receiving radio frequency signals therebetween. The method comprises the steps of the radio interface unit and the portable terminal having compact communication format for communications therebetween; the radio interface unit and the portable terminal having an extended communication format for communications therebetween; and the radio interface unit and the portable terminal using the compact communications format as a default communications mode.
Patent NZ-595368-A (NZ)
Title: A receiver and a transmitter
Inventor: BIRCH NICHOLAS
IPC: H04N5/44
Filed: 2010-03-24
Abstract: 595368 A device and a method of processing a multiplexed data stream are disclosed. The device comprises at least one receiver for a testing device for a multiplexed data stream in the form of a digital television signal and at least one testing device decoder for the testing device. The multiplexed data stream comprises a plurality of encoded data components, each being a television channel. Each of the encoded data components comprises a plurality of sections with each section representing different functionality. The at least one receiver comprises an input for inputting a plurality of encoded data components; a demultiplexer for demultiplexing the plurality of encoded data components; and a plurality of outputs each for outputting a demultiplexed one of the plurality of encoded data components. The at least one receiver is arranged, such that, in use, a plurality of encoded data components each being a television channel received at the input of one of the at least one receiver are demultiplexed by the demultiplexer and a demultiplexed one of the plurality of encoded data components is output from one of the plurality of outputs and input into at least one of the at least one decoder. The at least one decoder comprises at least one decoding portion for only decoding the section or sections required for testing an aspect of interest. At least one of the at least one decoding portions is an audio decoder for decoding audio and/or an interactive decoder for decoding interactive content and/or a text decoder for decoding text; and the or each decoder is arranged such that it discards one or more sections from the digital television signal not required for testing the aspect of interest.
Patent NZ-600582-A (NZ)
Title: Granules for pharmaceutical preparations, methods and apparatus for their production
Inventor: HOEG-MOLLER CARSTEN
IPC: A61K9/16
Filed: 2010-12-15
Abstract: Disclosed are improved granular pharmaceutical preparations, together with improved methods and apparatus for preparation of granules for use in such preparations. granules include an active pharmaceutical ingredient and have a length along an axis of extrusion and a cross-sectional dimension of extrusion, wherein at least 80% by number of all of said granules in the composition have an aspect ratio of said length to said cross-sectional dimension of greater than 0.7 and less than 2.2. The granules exhibit a more sharply peaked length distribution, and hence aspect ratio distribution, and have a consequently much sharper dissolution profile after further processing. Methods for their preparation and a length sorting apparatus for use in such methods is also disclosed.
Patent NZ-603453-A (NZ)
Title: Delivery of cholesteryl ester to steroidogenic tissues
Inventor: KRAUSE Brian
IPC: A61P15/10
Filed: 2011-05-06
Abstract: Disclosed is a method of treating a condition characterized by reduced function of steroidogenic tissues comprising: administering to a patient in need thereof, an agent selected from the group consisting of lecithin: cholesterol acyltransferase (LCAT). Wherein the condition is characterized by adrenal insufficiency, including acquired adrenal insufficiency, low testosterone production, or low ovarian hormone production, the condition being selected from Addison’s disease, systemic inflammatory response syndrome, infection, inflammation, sepsis, trauma, burns, liver disease, including but not limited to hepatitis, hepatorenal syndrome, fibrosis, cirrhosis, bile duct hyperplasia, or bile duct atresia, kidney disease, organ transplant, heavy metal poisoning, auto-immune disease, arthritic disease, liver disease, conditions characterized by low testosterone production, including but not limited to male menopause, erectile dysfunction, or conditions characterized by low ovarian hormone production, including but not limited to menopause.
Patent NZ-603807-A (NZ)
Title: A heterogeneous inseminate system
Inventor: ROSENSTEIN MAURICE A
IPC: A61B17/43
Filed: 2011-06-08
Abstract: Disclosed is a heterogeneous inseminate, comprising: a) a first amount of sperm of a first animal; and b) a second amount of sperm of a second animal combined with said first amount of sperm of said first animal, said first animal and said second animal of the same species, wherein one of said first amount of sperm or said second amount of sperm comprises sex selected sperm; wherein said first amount of sperm has sufficient concentration in said heterogeneous inseminate to increase motility of said second amount of sperm in said heterogeneous inseminate. Also disclosed is a method of manufacture of the heterogeneous inseminate.
Patent NZ-606508-A (NZ)
Title: Composites comprising biologically-synthesized nanomaterials
Inventor: CURRAN SEAMUS
IPC: C08K7/00
Filed: 2009-11-02
Abstract: Disclosed is a composite material comprising: - a polymer material; and - biologically synthesised tellurium nanorods dispersed in the polymer material; wherein the composite material has a non-linear optical limiting response, and wherein the biologically synthesised tellurium nanorods are not bacterially synthesised tellurium nanorods.
Patent NZ-606730-A (NZ)
Title: Methods for treating antipsychotic-induced weight gain
Inventor: DEAVER DANIEL
IPC: A61P25/18
Filed: 2011-08-23
Abstract: Provided is the use of opioid receptor modulator compounds of Formula I, wherein the variables are as defined in the specification, in the treatment of weight gain associated with the use of antipsychotic agents. Further provided are compositions comprising an opioid receptor modulator compound of Formula I and an atypical antipsychotic agent.
Patent NZ-609595-A (NZ)
Title: Motorized electrical switch mechanism
Inventor: HEMMINGER RODNEY C
IPC: H01H5/04
Filed: 2013-04-18
Abstract: A relay, particularly for a power meter, includes a pair of movable contacts 27a, 27b which can be moved by moving the contact arms 105a, 105b to open or close the relay. The current from the line terminals 20a, 20b flows via the current sensor 15 conductors 22a, 22b through the contact arms and contacts to the load terminals 25a, 25b. The contact arms are moved by a linearly moving actuator 200 which in turn is moved by a cam follower which follows the cam surfaces on the edges of the oppositely rotating cams 125a, 125b which are driven by the electric motor 110 and worm gear link between the motor and the cams. Springs 220, 220a connected between the cams and follower on the actuator 200 are “loaded” respectively and oppositely in tension and compression as the cams rotate so that when the cams have rotated to a position to allow the actuator to move the contact arms from the closed to the opened position or from the opened to the closed position, the energy in the springs is released to quickly move the actuator and the contact arms from the one to the other of the positions.
Patent NZ-612132-A (NZ)
Title: Immunomodulation using placental stem cells
Inventor: PALUDAN CASPER
IPC: A61K35/50
Filed: 2006-10-13
Abstract: Discloses the use of a placental stem cell population, wherein at least 80% of said placental cells in the population are CD10+, CD34-, CD105+ and CD200+ in the preparation of a medicament for suppressing an immune response associated with graft-versus-host disease.
Patent NZ-623716-A (NZ)
Title: Antigen-binding molecule capable of binding to two or more antigen molecules repeatedly
Inventor: IGAWA TOMOYUKI
IPC: G01N33/50
Filed: 2009-04-10
Abstract: Disclosed is a method of screening for an antibody, which comprises the steps of: Determining the antigen-binding activity of an antibody at pH 6.7 – pH 10.0 Determining the antigen-binding activity of an antibody at pH 4.0 – pH 6.5 Selecting an antibody whose antigen-binding activity at pH 6.7 - 10.0 is greater than the antigen-binding activity at pH 4.0 – pH6.5. Further discloses a method of screening for an antibody whose binding activity at a first pH is greater than that at a second pH, which comprises the steps of: binding an antibody or an antibody library encoded by one or more genes encoding one or more antibodies to an antigen-immobilized column under the condition of pH 6.7 to pH 10.0; eluting the antibody that had bound to the column at the first pH from the column under the condition of pH 4.0 to pH 6.5; and collecting the eluted antibody, or amplifying the gene encoding the eluted antibody from the antibody library and producing the antibody using the gene obtained thereby obtained.
Patent NZ-630646-A (NZ)
Title: Improvements in and relating to packaging and machines therefor
Inventor: VAN BERLO PATRICK PETRUS ANTONIUS MARIA
IPC: D21H27/10
Filed: 2014-09-09
Abstract: A protective wrapping for articles made from single face paperboard is disclosed. This packaging (1) is capable of being wrapped around irregular shaped objects along either the longitudinal or transverse axes of the laminate due to a series of intersecting creases (2, 4, 5) being formed over the single face paperboard. The specification discloses that it would be desirable if there could be provided a packaging material which is more eco-friendly than plastic bubble wrap, yet is sufficiently flexible or bendable to effectively wrap around irregular objects, robust, light weight and is relatively inexpensive to produce. An apparatus to produce such an article is also disclosed.
Patent NZ-701790-A (NZ)
Title: Density phase separation device
Inventor: BARTFELD BENJAMIN
IPC: G01N1/10
Filed: 2010-05-14
Abstract: A mechanical separator (40) for separating a fluid sample into first and second phases within a collection container (82) is disclosed. The mechanical separator (40) has a separator body with a through-hole (46) adapted for allowing fluid to pass through. The separator body includes a float (42), having a first density, and a ballast (44), having a second density greater than the first density. The body also includes a seal between the separator (40) and the container (82). In use the separator changes position in a centrifuge from a position in which fluid can flow (F) through the hole to a closed position.
Patent NZ-719085-A (NZ)
Title: Off-road vehicle protective plates
Inventor: BERRYMAN MARC JOHN
IPC: B60J11/00
Filed: 2014-10-10
Abstract: Vehicles driven in an off-road environment are exposed to conditions which can scratch the surface of the vehicle. This is unsightly and detracts from the vehicle. The present invention provides a protection system for protecting at least an external portion (25) of these vehicles. The present system comprises at least one protective plate (11) which is adapted to be releasably secured to the at least an external portion (25) of a vehicle to protect the external portion (25) it is releasably secured to, the at least one protective plate (11) being adapted to be complementary in shape to the external portion (25) of the vehicle it is adapted to cover, the at least one protective plate is releasably secured to the vehicle using at least one magnet (15).