baber/WOPTO huggingface dataset:
Patent NZ-576639-A (NZ)
Title: Crystalline modification of fipronil
Inventor: SAXELL HEIDI EMILIA
IPC: A01P7/00
Filed: 2007-11-05
Abstract: Disclosed is a process for preparing solid fipronil comprising at least 85 percent by weight of the crystalline modification I of fipronil being present in the monoclinic system having the centrosymmetric space group C2/c comprising the steps of: step i) preparing a solution of a solid form of fipronil being different from the crystalline modification I in a solvent S comprising at least one acetonitrile, dimethylsulfoxide, or at least one benzene derivative; step ii) effecting crystallization of fipronil; and step iii) isolating the resulting precipitate wherein, in case the solvent S is pure acetonitrile, the crystallization step ii) is conducted at temperatures below 40 degrees Celsius and in case the solvent S is pure dimethylsulfoxide, the crystallization step ii) is conducted at temperatures below 80 degrees Celsius.
Patent NZ-580463-A (NZ)
Title: Methods for treating cancer with combination of clofarabine and radiation
Inventor: XU BO
IPC: A01N43/02
Filed: 2008-04-14
Abstract: The use of the compound of formula (I) wherein: Y is F, Cl or Br; R2 is hydrogen or acyl for treating cancer, cancerous cells or precancerous cells. Preferably the compound is clofarabine. The compound can be formulated for administration with radiation and is useful in potentiating radiotherapy in the treatment of cancer. Preferably in the radiation is between 0.1 Gy to 10 Gy of ionising radiation.
Patent NZ-583520-A (NZ)
Title: A new method for making krill meal
Inventor: OISTEIN HOSTMARK
IPC: A23L17/10
Filed: 2008-08-29
Abstract: Disclosed is a process for preparing phospholipid compositions from krill comprising phospholipids and proteins comprising: mixing said krill with water to increase the temperature of said krill to about 65 to 80°c to form a first solid phase and a first aqueous phase comprising said phospholipids and proteins; separating said first solid phase from said first aqueous phase; and separating a protein and phospholipid coagulate fraction from said first aqueous phase by heating said first aqueous phase at a temperature sufficient to form a phospholipid-protein coagulate fraction and separating said phospholipid-protein coagulate fraction from said aqueous phase, wherein said phospholipid-protein coagulate fraction comprises about 20% to 50% protein w/w and about 50% to 65% lipids w/w on a dry base and wherein said lipids further comprise 35% to 50% w/w phospholipids expressed as a percentage of total lipids.
Patent NZ-587936-A (NZ)
Title: Molding of transponder electronics and antenna into hard plastic part for ear tag
Inventor: VAN WIJK ANTON
IPC: A01K11/00
Filed: 2005-10-20
Abstract: The electronic component 50 and the antenna winding 51 of an electronic transponder for an animal ear tag 1 are arranged on the rear side 52 of an injection moulded hard plastic part 53, 54 and a plastic material is injected around the transponder to form a layer on the rear side which fully encloses the transponder. The plastic material is chosen to ensure a firm connection to the hard plastic part. (62) Divided Out of 554909
Patent NZ-589145-A (NZ)
Title: LED bulb with a heat dissapating radiator sized and shaped for replacing existing halogen bulbs
Inventor: FAN JINJING
IPC: F21V29/00
Filed: 2008-05-27
Abstract: An LED bulb for replacing a reflect cup shaped halogen bulb which can be used with an existing mounting base of the reflect cup shaped halogen bulb. The LED bulb comprises a shell, a collective lens, an LED circuit board, one or more LEDs arranged on the LED circuit board, a radiator and a driver. The shell has a hollow structure. The LED circuit board is disposed within a cavity of the shell and connected to the radiator. The collective lens is disposed at a lower end portion of the cavity of the shell. The shell, the radiator and the driver are connected to each other from bottom to top in sequence. On a circumferential exterior wall at a lower end of the shell there is a circular ring. The circular ring is removably connected to the shell. The outer diameter and the height of the circular ring are equal to an outer diameter of a reflect cup of the reflect cup shaped halogen bulb and a height of an annular flange of the reflect cup, respectively. The outer diameter of the radiator is less than or equal to a mounting outer diameter of the mounting base. The radiator comprises a first radiator portion and a second radiator portion located under the first radiator portion. An outer diameter D1 of the first radiator portion and an outer diameter D2 of the second radiator portion meet this formula: D2?D1. When the LED bulb is mounted to the mounting base of the reflect cup shaped halogen bulb, a distance from a lower end of the first radiator portion to a bottom face of the mounting base is larger than a height of the mounting base. The outer diameter of the first radiator portion of the radiator is equal to the mounting outer diameter of the mounting base. The radiator is constituted of a central post, a plurality of fins disposed on the circumferential outer wall of the central post in a radiating spaced configuration and a bossing disposed around outsides of said plurality of fins. Each of the fins is constituted by an upper wing and a lower wing integrated with the upper wing, and a width of the upper wing is larger than that of the lower wing. The bossing is disposed at outsides of the upper wings. The upper wings of the plurality of fins and the bossing constitute the first radiator portion of the radiator and the lower wings of the plurality of fins constitute the second radiator portion of the radiator.
Patent NZ-590042-A (NZ)
Title: Hydrogenation of multi-brominated alkanes
Inventor: WAYCUILIS JOHN J
IPC: C07C1/26
Filed: 2009-06-12
Abstract: Disclosed is a method comprising: reacting at least hydrogen gas and multi-brominated alkanes to form a hydrogenated stream comprising brominated alkanes having fewer bromine substituents than the multi-brominated alkanes reacted with the hydrogen; and reacting at least reactant mono-brominated alkanes in the presence of a catalyst in a synthesis reactor to form synthesis products comprising C3 or more hydrocarbons, wherein the reactant mono-brominated bromines comprise at least a portion of the mono-brominated alkanes formed from the bromination reactants and at least a portion of the additional mono-brominated alkanes formed from the hydrogenation reactants, wherein the catalyst comprises a synthetic crystalline aluminosilicate oxide framework. Also disclosed is a system for carrying out the process comprising a bromination reactor, a hydrogenation reactor in fluid communication with the bromination reactor and a synthesis reactor containing a crystalline aluminosilicate oxide catalyst in fluid communication with the hydrogenation reactor.
Patent NZ-590078-A (NZ)
Title: High precision blasting delay system for non-electric activation of blasting charges at a preset time
Inventor: PEREZ CORDOVA PIO FRANCISCO
IPC: F42B3/16
Filed: 2010-12-20
Abstract: A high precision blasting delay system for non-electric activation of blasting-charges at a preset time is disclosed. The high precision blasting delay system includes a watertight plastic container which contains a base with fastening rails and contact supports for protecting the system from movement and vibration. The base is divided into compartments into which an electronic circuit is placed that performs control of the entire system and an electric detonator detonates the sequence of the blasting-charge. A shock tube transports the switched on detonation signal and sensors detect the activation of the shock tube where the sensors include an impact sensor. A micro-switch connects the electric energy source with the circuit, and an impact channelling device holds the shock tube and guides the expansive wave towards the impact sensor. The impact channelling device avoids internal disturbances due to movement caused by the force of impact while at the same time controlling, in a regulated manner, the sensor from directly connecting to the output terminal of the impact tube, so that it will be able to use the signal emitted in order to generate a pulse having power. The sensors are adapted to detect the different physical sizes emitted by the shock tube. The base is made of an impact resistant material for reducing the damage to electric circuitry and activation by impact to the electric detonator. The micro-switch is only activated in the device assembly with the explosive reaction booster charge.
Patent NZ-592685-A (NZ)
Title: Modulators of cystic fibrosis transmembrane conductance regulator
Inventor: BINCH HAYLEY
IPC: A61K31/439
Filed: 2009-10-23
Abstract: 592685 Disclosed is a compound of formula (I) which is an azabicyclic substituted on a phenyl group which in turn is substituted on a dihydroquinoline. Examples of compounds of formula (I) are: N-(4-(7-azabicyclo[2.2.1]heptan-7-yl)-2- (trifluoromethyl)phenyl)-4-oxo-5-( trifluoromethyl)-1,4-dihydroquinoline-3-carboxamide; N-(4-(7-azabicydo[2.2.1]heptan-7-yl)-2-cyanophenyl)-5-methyl-4-oxo-1,4-dihydroquinoline-3-carboxamide and N-[4-(7-azabicyclo[2.2.1]heptan-7-yl)-2-(3-dimethylaminoprop-1-ynyl)phenyl]-4-oxo-5-(trifluoromethyl)-1H -quinoline-3-carboxamide. Also disclosed are pharmaceutical compositions and kits comprising a compound of formula (I) Further disclosed is the use of a compound of formula (I) in the manufacture of a medicament for the treatment of diseases such as cystic fibrosis, COPD, liver diseases and Alzheimer's disease.
Patent NZ-594434-A (NZ)
Title: Compositions and methods for the treatment of cancer
Inventor: KO YOUNG HEE
IPC: A61K47/12
Filed: 2010-01-29
Abstract: The present disclosure relates to anti-cancer compositions, and associated methods, including an anti-cancer composition comprising: a cellular energy inhibitor having the structure according to formula I (I) wherein X is selected from the group consisting of: a nitro, an imidazole, a halide, sulfonate, a carboxylate, an alkoxide, and amine oxide; and R is selected from the group consisting of: OR’, N(R”)2, C(O)R”’, C 1 -C6 alkyl, C6-C 12 aryl, C1 -C6 heteroalkyl, a C6-C12 heteroaryl, H, and an alkali metal; where R1 represents H, alkali metal, C 1-C6 alkyl, C6-C12 aryl or C(O)R’”, R” represents H, C 1 -C6 alkyl, or C6-C 12 aryl, and R’” represents H, C1 -C20 alkyl or C6-C 12 aryl. The anti-cancer composition can additionally comprise at least one sugar, which stabilizes the cellular energy inhibitor by substantially preventing the inhibitor from hydrolyzing. Also, the anti-cancer composition can comprise a glycolysis inhibitor including 2-deoxyglucos. Further, the anti-cancer composition can comprise a biological buffer, including citrate that is present in an amount sufficient to at least partially deacidify the cellular energy inhibitor and neutralize metabolic by-products of the cellular energy inhibitor.
Patent NZ-594840-A (NZ)
Title: Fumigation control
Inventor: IVANINE SERGUEI
IPC: A01M13/00
Filed: 2010-02-26
Abstract: 594840 Disclosed is an apparatus and method for fumigating an enclosed space. The apparatus (10) comprises a flexible enclosure (12") that is inflatable and deflatable with a gaseous fumigant between an expanded configuration and a collapsed configuration. The flexible enclosure is positioned within the enclosed space prior to fumigant introduction. When the flexible enclosure is inflated, and subsequently expands, it displaces a volume of gas from the enclosed space. The apparatus also comprises an inlet (16) to receive gaseous fumigant for inflation of the flexible enclosure, as well as an outlet (20") and a valve. The valve opens and closes the outlet to release the gaseous fumigant from the enclosure via the outlet and into the enclosed space. A method for fumigating an enclosed space is also disclosed.
Patent NZ-602815-A (NZ)
Title: Contoured support insole
Inventor: MARTINEZ JACOB
IPC: A43B7/22
Filed: 2011-06-23
Abstract: 602815 A contoured insole especially advantageous for users with medium to high arches is disclosed. It comprises a generally foot-shaped base extending from a heel end to a toe end, which comprises a top surface and a bottom surface. The bottom surface of the base preferably further comprises two indentations formed integrally therein in a forefoot area and a heel area. A forefoot pad and a heel pad are secured to each of said indentations. Preferably, the base is made from a polyurethane foam. The pads are made from rubber or synthetic rubber. A top sheet is coextensive with and secured to the top surface of the base. The top sheet is generally a fabric which preferably has antimicrobial characteristics. In use, the foot of the wearer, with or without a sock or stocking thereon, rests upon the top sheet in the foot-receiving compartment of a user's shoe
Patent NZ-603411-A (NZ)
Title: Pazopanib compositions and their use in treating ocular diseases
Inventor: GUPTA MANISH K
IPC: A61P27/02
Filed: 2011-05-05
Abstract: Ophthalmic compositions that include about 10 mg pazopanib/mL of the composition and about 2 to about 13% w/w of a modified cyclodextrin as well as methods of making the same are described. Wherein the cyclodextran may be hydroxypropyl-β- cyclodextrin, methyl-β-cyclodextrin, β-cyclodextrin sulfobutylether and combinations thereof.
Patent NZ-605485-A (NZ)
Title: Water-based pesticidal suspension
Inventor: AWAZU TAKAO
IPC: A01N51/00
Filed: 2011-07-05
Abstract: Disclosed is a water-based pesticidal suspension comprising (a) an agricultural chemical or its salt having an aqueous solubility of from 500 mg/L to 6,000 mg/L at 20°C, wherein the agricultural chemical is flonicamid, (b) a polycarboxylate surfactant, (c) a sulfonate type surfactant, wherein the sulfonate type surfactant is at least one member selected from the group consisting of an alkyl sulfosuccinate, a lignosulfonate, a C8-18 alkyl benzene sulfonate and a C8-18 alkyl diphenyl ether disulfonate and (d) water.
Patent NZ-608823-A (NZ)
Title: Processes for preparation of lubiprostone
Inventor: HENSCHKE JULIAN P
IPC: C07C31/38
Filed: 2010-10-15
Abstract: This disclosure relates to a process for the synthesis of lubiprostone, also known as 7-[(1R,3R,6R,7R)-3-(1,1-difluoropentyl)-3-hydroxy-8-oxo-2-oxabicyclo[4.3.0]non-7-yl]heptanoic acid, which can undergo ring-chain tautomerisation (Scheme 1) and is the active pharmaceutical ingredient in the drug product Amitiza®, a gastrointestinal agent used for the treatment of chronic idiopathic constipation in adults. The synthetic process involves (I) coupling a cyclopentenone with an organocopper, (II) hydrogenation step, (III) an oxidation step and (IV) a final hydrolysis step using an enzyme. The disclosure also relates to key intermediates of this scheme and a process of purifying lubiprostone obtained using this process.
Patent NZ-611316-A (NZ)
Title: Histone inhibition
Inventor: STEPHENS ROSS WENTWORTH
IPC: A61K31/724
Filed: 2011-11-29
Abstract: Disclosed is the use of an effective amount of a polyanion for the manufacture of a medicament for the treatment of sepsis by inhibiting the cytotoxic activity of extracellular histones, wherein the polyanion does not have substantial anticoagulant activity; and wherein the polyanion is a polyanionic oligosaccharide having the general structure: A-(B)n-D (I) wherein A and B are each independently a cyclic monosaccharide or a cyclic deoxy monosaccharide; D is a cyclic monosaccharide, a cyclic deoxy monosaccharide, a ring-opened monosaccharide, or a sugar alcohol; n is an integer selected from 0, 1, 2, 3, 4, 5, 6, 7 and 8; and wherein each of the cyclic monosaccharide, the cyclic deoxy monosaccharide, the ring-opined monosaccharide, or the sugar alcohol is independently optionally substituted with SO3-, COO-, OPO3-, an optionally substituted alkyl, an optionally substituted alkenyl, an optionally substituted alkynyl, an optionally substituted aryl, or an optionally substituted aralkyl; and wherein the polyanionic oligosaccharide includes at least two anionic substituents selected from the group consisting of OSO3-, COO- and OPO3-.
Patent NZ-620113-A (NZ)
Title: Enterobacter sp. 638 and methods of use thereof
Inventor: NEWMAN LEE
IPC: C12N5/04
Filed: 2011-03-10
Abstract: Disclosed is a method for increasing fruit and/or seed productivity in a plant, the method comprising applying a composition to the plant in an amount effective for increasing fruit and/or seed productivity in the plant, wherein the composition comprises an isolated culture of Enterobacter sp. 638., Further disclosed are plants treated according to the method as disclosed herein.
Patent NZ-622376-A (NZ)
Title: Chemical looping process for partial oxidation of carbonaceous fuels
Inventor: VELAZQUEZ-VARGAS LUIS G
IPC: C01B32/40
Filed: 2014-03-13
Abstract: The disclosure relates to method for providing from a carbonaceous fuel a gaseous output that comprises carbon monoxide (CO) as a primary carbon-containing product, said method comprising contacting said carbonaceous fuel with metal oxide particles in a first, highest oxidation state in a first reactor having an essentially co-current flow pattern, said particles being reduced from said first oxidation state to a second, lower oxidation state, thereby providing said gaseous output. These particles may then be transported to a separate bed reactor to be oxidised and produce hydrogen gas (H2). The carbon monoxide may also be subjected to a water gas shift reaction to produce H2. The resulting gasses may be mixed to provide syngas, or subjected to the Fischer-Tropsch process or a Boudouard reaction.
Patent NZ-626696-A (NZ)
Title: Accessories for use with housing for an electronic device
Inventor: RAYNER GARY
IPC: H05K5/00
Filed: 2012-12-21
Abstract: Disclosed is an apparatus for covering at least part of a mobile computing device having a touch screen display where the mobile computing device has an electrical connection available at an outer surface of a housing that houses the mobile computing device. The apparatus comprises: an encasement for the mobile computing device that permits operation of the touch screen display and covers at least part of the mobile computing device that includes the electrical connection; an aperture passing through the inner surface and the outer surface of the encasement proximate the electrical connection of the mobile computing device; an electrical connection adapter having a body for closing the aperture in the encasement, the electrical connection adapter having a first electrical interface connected with the body, the first electrical interface for interfacing with the electrical connection of the mobile computing device when the body closes the at least one aperture in the encasement; the electrical connection adapter further having a second electrical interface connected with the body, the second electrical interface for transferring electrical power and/or data signals to and/or from the mobile computing device through the first electrical interface, the second electrical interface including a plurality of sealed, electrically-conductive members positioned at an outer surface of the body and accessible from outside of the encasement when the aperture is closed by the body; a plurality of electrical conductors extending through the body, each connecting a respective one of the sealed electrically-conductive members with the first electrical interface; and a gasket for sealing the electrical connection adapter with the encasement at the aperture.
Patent NZ-712568-A (NZ)
Title: Process operations for biomass fractionation
Inventor: DAY KENNETH JOHN CORYTON
IPC: D21C3/00
Filed: 2014-02-26
Abstract: A method of fractionating a biomass material comprising the steps of: (i) blending the biomass material with an acid catalyst and an organosolv reagent under an inert atmosphere to form a pre-treatment mix as a slurry; (ii) subjecting the pre-treatment mix to sonication to produce a fractionation mix; (iii) optionally heating the sonicated pre-treatment mix in an autoclave under pressure to form a fractionation mix; (iv) separating the solid and liquid components of the fractionation mix; (v) optionally washing the solid; (vi) optionally drying the solid; (vii) separating the liquid component into organic and aqueous components; and (viii) isolating lignin from the organic component and/or isolating hemi-cellulose from the aqueous component.
Patent NZ-714999-A (NZ)
Title: Treatment of cancer with naltrexone
Inventor: DALGLEISH ANGUS
IPC: A61K31/593
Filed: 2014-05-12
Abstract: The present invention provides novel therapeutic applications of low dose naltrexone (LDN). Said applications have been determined in light of the discovery by the present inventors that naltrexone acts as an antagonist of Toll-like receptor 9 (TLR9), an innate immune receptor which elicits the production of inflammatory cytokines when agonised. Chronic inflammation and TLR9 overexpression are characteristics of a number of disorders, including certain cancers. Accordingly, the present invention provides novel uses of naltrexone, naloxone, or methylnaltrexone in the manufacture of a medicament for the treatment of a subject having metastatic melanoma, breast cancer, cervical squamous cell carcinoma, gastric carcinoma, glioma, hepatocellular carcinoma, lung cancer, melanoma, recurrent glioblastoma, or colorectal cancer characterised by TLR9 overexpression and/or overactivity of TLR9-mediated signalling, wherein the naltrexone, naloxone, or methylnaltrexone is to be orally administered to the subject at a dose of from 0.01 mg/kg to 0.08 mg/kg, and wherein the subject is to be, or has been, administered with at least one chemotherapeutic agent. The present invention also provides novel uses of naltrexone, naloxone, or methylnaltrexone in the manufacture of a medicament for use in the supportive care of subject having metastatic melanoma, breast cancer, cervical squamous cell carcinoma, gastric carcinoma, glioma, hepatocellular carcinoma, lung cancer, melanoma, recurrent glioblastoma, or colorectal cancer wherein the subject is characterised as having TLR9 overexpression and/or overactivity of TLR9-mediated signalling, wherein the naltrexone, naloxone, or methylnaltrexone is to be orally administered to the subject at a dose of from 0.01 mg/kg to 0.08 mg/kg, and wherein the subject is to be, or has been, administered with at least one chemotherapeutic agent.
Patent NZ-719079-A (NZ)
Title: Parasiticidal oral veterinary compositions comprising systemically-acting active agents, methods and uses thereof
Inventor: SOLL MARK D
IPC: C07D261/04
Filed: 2013-01-31
Abstract: Soft chewable veterinary compositions are used for combating ectoparasites and endoparasites in animals, comprising at least one systemically-acting active agent of formula I such as afoxolaner in combination with a pharmaceutically acceptable carrier selected from polyethylene glycol stearate and a polyethylene glycol hydroxystearate.