baber/WOPTO huggingface dataset:
Patent NZ-334818-A (NZ)
Title: Preparation of N-alkyl-acylamino-triiodophenyl compounds
Inventor: GULBRANDSEN TRYGVE
IPC: A61K49/04
Filed: 1997-08-29
Abstract: N-alkyl-acylamino-phenyl-carboxylic acids are prepared by liquid phase acylation and the subsequent N-alkylation of a corresponding amino-phenyl-carboxylic acid (or carboxylic acid derivative).  The acylation is acid catalysed and effected by adding an acylating agent such as an acid halide or acetic anhydride.  The product is base hydrolysed at pH 11 -12 to remove O-acyl groups from the resulting N-acyl-amino intermediate.  The solution pH is adjusted to an appropriate basic value for N-alkylation and an alkylating agent selected from 1-halo-2,3-propanediols, glycidol, 1-halo-3-methoxy-2-propanols, 1,3-halo-2-propanols and epichlorohydrin is added. Specific compounds prepared by this process are non-ionic iodinated X-ray contrast agents, such as iomeprol, ioversol, ioxilan, iotrolan, ioxaglate, iodecimol, 2-iopyrol, 2-iopiperidol, iohexol, iopentol and iodixanol.
Patent NZ-336399-A (NZ)
Title: Fluid mixer for mixing reactive fluids at elevated temperatures and pressures having an expander with an insert and process using the same
Inventor: WENTINCK HENDRIK MARTINUS
IPC: B01F5/06
Filed: 1998-01-06
Abstract: Apparatus for mixing reactive fluids which are capable of ignition or explosion, at elevated temperature and pressure, for subsequent conversion by contact with a catalyst such as a (partial) oxidation catalyst or in a combustion zone, comprising in sequence an upstream inlet end, a mixer, an expander, a diffuser and a downstream outlet end is claimed. The outlet end being characterized by a greater available cross sectional area than any of the inlet end, mixer and expander, and the expander having substantially increasing internal cross sectional area in downstream direction wherein the available cross sectional area of the expander at any point along its length is less than the difference in internal cross section of the expander at its downstream and its upstream ends. A process for the catalytic partial oxidation of hydrocarbon feedstock using the apparatus is claimed.
Patent NZ-336440-A (NZ)
Title: Poly(diallylamine) polymers useful as bile acid sequestrants
Inventor: HOLMES-FARLEY STEPHEN RANDALL
IPC: A61P3/06
Filed: 1997-12-29
Abstract: Use of a poly(diallylamine) polymer, where more than 10 % of the amino nitrogen atoms are substituted by a hydrophobic substituent selected from among substituted and unsubstituted linear, branched or cyclic C3-C24-alkyl, C3-C24-alkenyl, arylalkyl and aryl groups, in the manufacture of a medicament for removing bile acids from a human patient. Also described is the use of a polymer characterised by a diallylamine monomer, where the amino nitrogen atom is substituted with a C2-C20-ammonioalkyl group, in the manufacture of a medicament for removing bile acids from a human patient. Also described is a cross-linked polymer characterised by a diallylamine monomer, where the amino nitrogen atom is substituted with a C2-C20-ammonioalkyl group.
Patent NZ-503145-A (NZ)
Title: 8a-Azalides as veterinary antimicrobial agents to treat bacterial respiratory infection
Inventor: KROPP HELMUT
IPC: C07H17/00
Filed: 1998-09-04
Abstract: 8a-Azalides are useful in the treatment and prevention of bacterial respiratory and enteric infections in livestock animals, particularly in cattle and swine.
Patent NZ-503390-A (NZ)
Title: Isoquinolines useful as urokinase inhibitors
Inventor: BARBER CHRISTOPHER GORDON
IPC: C07D491/056
Filed: 1998-10-05
Abstract: An isoquinoline derivative or a pharmaceutically acceptable salt thereof has the formula (I) wherein: one of R1 and R2 is H and the other is N=C(NH2)2 or NHC(=NH)NH2; R3 is H, halogen, alkyl optionally substituted by one or more halogen, or alkoxy optionally substituted by one or more halogen; R4, R5, R6 and R7 are each independently H, OH, halogen, alkyl optionally substituted by one or more halogen or OH, alkoxy optionally substituted by one or more halogen, CN, COalkyl optionally substituted by one or more halogen, (Cm-alkylene)CO2R8, O(Cn-alkylene)CO2R8, O(Cn-alkylene)CN, (Cn-alkylene)CN, (Cm-alkylene)CONR9R10, (Cm-alkylene)NR9COR10, O(Cn -alkylene)CONR9R10, (Cm-alkylene)NR9SO2R11, (Cm-alkylene)S(O)pR11, (Cm-alkylene)SO2NR9R10, CH=CHCOR8, CH=CHCONR9R10, CH=CHSO2R8, CH=CHSO2NR9R10, CH=CHSO2aryl or a group of formula X-aryl or X-het or, where two of R4, R5, R6 and R7 are attached to adjacent carbon atoms, they can be taken together to form an -O(Cn-alkylene)-O-moiety; R8 to R11 are as defined in the specification; X is a direct link, Cn-alkylene, O, (Cn-alkylene)O, O(Cn-alkylene), CH(OH), alkylOH, CO, S(O)p (Cm-alkylene), (Cm-alkylene)S(O)p, CH=CH, or CºC; m is from 0 to 3, n is from 1 to 3, and p is an integer from 0 to 2. A pharmaceutical composition thereof is useful as a urokinase inhibitor.
Patent NZ-503458-A (NZ)
Title: The preparation of a stable, aqueous suspension of a starter culture where the propagation of a mother culture into the bulk starter is not required
Inventor: HOIER ERIK
IPC: A23C19/032
Filed: 1998-08-24
Abstract: A delivery system for introduction of a starter culture directly into a dairy process line, comprising a sealed enclosure having outlet means (2) for connecting the enclosure (1) to the process line, the sealed enclosure containing a concentrate of the starter culture and/or milk clotting enzyme. The system can be used to introduce a dairy starter culture directly into a closed dairy process line without risk of contamination. The microbial starter culture can be combined with an aqueous medium to obtain an aqueous suspension of the microbial starter culture.
Patent NZ-506172-A (NZ)
Title: Sago fluidity starch
Inventor: HANCHETT DOUGLAS J
IPC: A23L9/10
Filed: 2000-08-08
Abstract: A sago starch having a water fluidity of fr5om about 40 to about 80 having a gel strength of at least 100% greater than a comparable corn fluidity starch having a WF of from about 40 to about 80 wherein both the sago starch and the corn starch are evaluated at a 10% solids content.
Patent NZ-506460-A (NZ)
Title: Aqueous formulations of parasiticides for skin application
Inventor: SIRINYAN KIRKOR
IPC: A01N25/22
Filed: 1999-02-10
Abstract: An aqueous composition for dermal control of parasitic insects on animals by means of agonists or antagonists of nicotinergic acetylcholine receptor of insects, which comprises: (a) 1-20 wt.% of agonists or antagonists of nicotinergic acetylcholine receptor of insects as active compound; (b) 2.5-15 wt.% water; (c) at least 20 wt.% of solvents such as alcohols or optionally substituted pyrrolidones; (d) 5-50 wt.% of solvents such as cyclic carbonates or lactones; (e) optional additives such as thickeners, spreading agents, colorants, antioxidants, propellants, preservatives, adhesives or emulsifiers; and (f) optional active compounds where the sum of active compounds, solvents and additives add up to 100% by weight.
Patent NZ-517403-A (NZ)
Title: Game method and apparatus
Inventor: SIEWERT NEIL
IPC: A63F5/00
Filed: 2000-07-24
Abstract: A game playing apparatus is described that displays in an image space (12) an aspect of a playing environment and overlays on the image space zones (14, 16) that have relevance to the playing environment. An event occurs in the playing environment in a delineated zone. A game participant is able to mark (18) with a marker a zone or zones before the event in anticipation of a reward if they mark the zone in which the event occurs. Their reward may be set by predetermined odds available before the event or a portion of pooled wagers. The playing environment may be a live event, a live sporting event or a pre-planned scenario. The image space (12) may only be a representation of the playing environment or an aspect of the playing environment. The game participant may wager remotely of the game apparatus with remote control devices that allow them to mark and wager. The remote control device may be built into other devices such as mobile telephone handsets.
Patent NZ-522074-A (NZ)
Title: Indole derivatives with vascular damaging activity
Inventor: ARNOULD JEAN-CLAUDE
IPC: A61P43/00
Filed: 2001-05-25
Abstract: A compound of formula (I) is described wherein: R1 and R2 are independently selected from hydrogen, halogen, -CN, a hydrocarbyl group or a group of formula (II): wherein in formula (II) W is aryl or a heterocyclic group; R4 is independently selected from hydrogen, halogen, -OH, amino, alkanoylamino,-OPO3H2, or a hydrocarbyl group, wherein the amino group is optionally substituted by an amino acid residue and the hydroxy group is optionally esterified or two R4 groups together form an optionally substituted cyclic or heterocyclic group; X is selected from-S-, -O-, -S(O)-, -S(02)- and NH-;p is an integer from 0 to 4; and q is an integer from 1 to 4; R3 and R10 are independently selected from hydrogen, lower alkyl or a group of formula (IV) of -(CH2)t-C(O)-Y-(CH2)r-Z-R6; wherein in formula (IV) Y is -NH-, -0-or a bond; Z is -NH-, -O-, -C (O)- or a bond; r is from 0 to 4; t is from 0 to 1; R6 is hydrogen, a hydrocarbyl group or a group of formula (V) of -(CH2)n-O-P(O)(OR7)(OR8) wherein in formula (V) n is an integer of from 1 to 6, and; R7 and R8 are independently selected from hydrogen or a hydrocarbyl group; and R11 is hydrogen or lower alkyl; or a salt or solvate thereof; provided that: i) when R1 is an unsubstituted phenylthio group (Ph-S-), R2 is H, R10 is H and R11 is H then R3 is neither H nor -C(O)-O-CH2CH3; and ii) R1, R2 and R3 are not all hydrogen. The compounds can be use din the manufacture of a medicament for to inhibit and/or reverse and/or alleviate symptoms of angiogenesis.
Patent NZ-526202-A (NZ)
Title: Orally ingestible preparation of mistletoe lectins, ML-I, ML-II and ML-III and methods fro treating cancer and autoimmune diseases
Inventor: PRYME IAN
IPC: A61P37/02
Filed: 2001-11-12
Abstract: A composition of matter consists of mistletoe lectin I (ML-I), mistletoe lectin (ML-ii) and mistletoe lectin III (ML-III), and excludes nausea-inducing compounds. Also described is a method of producing the composition from Viscum album. The composition can be used in pharmaceutical compositions for treating cancer, autoimmune diseases, such as arthritis, rheumatic disease, asthma and emphysema, and general fatigue. The composition may further comprise arginine for augmenting the effect of the preparation.
Patent NZ-530370-A (NZ)
Title: Single winding BEMF sensing brushless DC motor
Inventor: HARWOOD JONATHAN DAVID
IPC: H02P6/18
Filed: 2003-12-22
Abstract: A method of electronically commutating a permanent magnet rotor brushless DC motor having three phase stator windings for producing rotating magnetic flux that comprises the steps of: (a) Commutating current to successive combinations of two windings to cause flux rotation in the desired direction; (b) Sensing in only one of the windings the periodic back EMF induced by rotation of the permanent magnet rotor; (c) Sensing enabled in two out of six 60 degree intervals of flux rotation when the sensed winding has no current commutated to it; (d) Digitising the sensed back EMF signal in the one winding by detecting the zero-crossings of the signal; (e) Determining a half period time of the signal by obtaining a measure of the time between the pulse edges in the digitised signal which are due to zero-crossings; and (f) From the half period time deriving the 60 degree flux rotation time (commutation period) and causing each commutation to occur at times that are substantially defined by each logic transition in the digitised signal due to zero-crossings and at the derived 60 and 120 degree angles of flux rotation which follows the zero-crossings.
Patent NZ-537177-A (NZ)
Title: Modular construction system with each block having paired slabs with void for reinforcing member(s)
Inventor: BOLT DIRK
IPC: E04B1/02
Filed: 2003-05-12
Abstract: A modular construction system is described. The system includes blocks composed of structural slabs and spacers, with the spacers being arranged to form orthogonal and diagonal cavities extending within the blocks. When a number of blocks 1 are combined, the cavities combine to extend across blocks. Reinforcing members in the form of joists can be located within the cavities, together with fastening members, to secure the construction. The principal system components may be manufactured from second-grade and/or reclaimed wood-based products and the like, to provide an inexpensive construction material. Additional cladding members or fascias can be mounted to the slabs, to alter aesthetic appearance or to provide functional properties such as insulation.
Patent NZ-539579-A (NZ)
Title: Amino acid composition for improving central nervous function
Inventor: ABE TAKASHI
IPC: A61P25/28
Filed: 2003-09-30
Abstract: An amino acid composition or an amino acid solution for decreasing serotonin concentrations in the brain, wherein the respective amino acids are contained such that 2-15 moles of threonine, 4-30 moles of proline, 7-20 moles of glycine, 4-8 moles of valine, 3-9 moles of isoleucine, 2-12 moles of leucine, 1-9 moles of tyrosine, 0.5-5 moles of phenylalanine, 5-11 moles of lysine, 0.1-5 moles of aspartic acid, 0.1-5 moles of serine, 0.1-4 moles of glutamic acid, 0.1-12 moles of alanine, 0.1-5 moles of methionine, 0.1-5 moles of tryptophan, 0.1-5 moles of histidine and 0.1-5 moles of arginine.
Patent NZ-546264-A (NZ)
Title: Implantable penile prosthesis pump
Inventor: KUYAVA CHARLES C
IPC: A61F5/00
Filed: 2004-10-01
Abstract: A penile prosthesis (100) is provided, which includes at least one cylinder (112, 114), a reservoir (118), and a pump (116) including a pump housing, at least one reservoir channel (124) fluidly coupling the pump housing to the reservoir, at least one cylinder tube (120, 122) fluidly connecting the pump housing to the cylinders, a fluid passageway fluidly coupled to the reservoir channel and a transfer chamber, wherein the transfer chamber is fluidly coupled to the at least one cylinder tube, and a bypass chamber comprising bypass input and output channels and a bypass check-valve biased towards a closed position. The pump also includes a pump bulb fluidly connected to the fluid passageway between the bypass input channel and the bypass output channel along the length of the fluid passageway. Also disclosed is a pump for transferring fluid between a reservoir and at least one cylinder within a penile prosthesis.
Patent NZ-547481-A (NZ)
Title: Heterocyclic inhibitors of mek and methods of use thereof
Inventor: MARLOW ALLISON L
IPC: C07D491/02
Filed: 2004-11-18
Abstract: Disclosed are heterocyclic compounds of the formula (I) and pharmaceutically acceptable salts and prodrugs thereof, wherein R1, R2, R7, R8 and R9, W, X and Y are as defined in the specification. Such compounds are MEK inhibitors and useful in the treatment of hyperproliferative diseases, such as cancer and inflammation, in mammals, and inflammatory conditions. Also disclosed are methods of using such compounds in the treatment of hyperproliferative diseases in mammals and pharmaceutical compositions containing such compounds.
Patent NZ-553912-A (NZ)
Title: Radiant therapeutic heating apparatus
Inventor: DOCHERTY FRANCIS G
IPC: A61F7/00
Filed: 2005-09-01
Abstract: A radiant heat therapeutic heating apparatus 10 adapted to fit about a portion of the user's body, comprises a radiant heat generator 25 adapted to radiate energy at a body penetrating wavelength and coupled to an electrical energy source 34, a curved resilient stiffener adapted to prevent creasing of the radiant heat generator 25 and to position the portion of the users body to be treated in a therapeutic position, and a covering 13 with a pocket 70 for housing the radiant heat generator 25.
Patent NZ-555493-A (NZ)
Title: Method of transporting persons in a building
Inventor: FINSCHI LUKAS
IPC: B66B1/14
Filed: 2005-11-28
Abstract: A method of transporting persons in a building by means of a lift installation which comprises at least one lift cage (11) is disclosed. The lift cage is entered by persons at at least one first (S1) or second (S2) access storey. At least one destination storey (S3, S4, S5, S6) is fixedly allocated to each access storey, and the access storeys are not destination storeys for each other. Persons boarding the lift cage at the first access storey are transported to a first fixedly allocated destination storey and persons boarding the lift cage at the second access storey are transported to a second fixedly allocated destination storey.
Patent NZ-571453-A (NZ)
Title: Smoking article with a restrictor that reduces carbon monoxide but maintains a high resistance to draw
Inventor: LI SAN
IPC: A24D3/04
Filed: 2007-03-28
Abstract: A smoking article filter (114) is disclosed. The filter (114) includes a flow restrictor (126) and a cavity (146) downstream of the flow restrictor. The restrictor (126) reduces carbon monoxide but maintains a high resistance to draw. The flow restrictor (126) includes an orifice (130) or flow channel for directing smoke into the cavity. The filter (114) is attached to a tobacco rod (112) with tipping paper (116) and includes an air-admissible ventilating zone (140) at a location downstream of the restrictor (126). The invention also provides methods of making filters and smoking articles.
Patent NZ-572366-A (NZ)
Title: THE USE OF NICOTINE, ANALOGUES THEREOF, PRECURSORS THEREOF OR DERIVATIVES THEREOF IN THE TREATMENT OF VARIOUS PATHOLOGICAL PROCESSES CAPABLE OF IMPROVEMENT WITH a-MSH ADMINISTERED IN PROPHYLACTIC OR THERAPEUTIC FORM
Inventor: SOLIS HERRERA ARTURO
IPC: A61K31/465
Filed: 2006-05-08
Abstract: Disclosed is the use of nicotine in the preparation of a medicament for the treatment of: post traumatic bleeding (hyplema); proliferative retinopathies in eye fibroblasts; initial stages of retrolental fibroplasias; proliferative diabetic retinopathies; post traumatic proliferative retinopathies; proliferative retinopathies caused by hypoxia; infectious conditions or infectious syndromes to one or more of a liver, kidney, and lung; degenerative osteoarthrosis; eclampsyia; Parkinson or Alzheimer diseases; rejection of transplanted tissues; ischemia to a kidney, lung or intestines; deterioration to a liver or blood vessels caused by lipopolysaccharides; bacterial infections of a liver or liver cirrhosis; depression; obesity; pain relief in late term pregnancy, in the absence diabetes; hypertension or neuropathy antecedents; such that in use the medicament Induces or stimulates release of alpha-MSH.
Patent NZ-574270-A (NZ)
Title: Formulations comprising a vitamin and castor oil alkoxylate, and the use thereof to make fortified feed and personal care formulations
Inventor: OLAUSSON INGER
IPC: A23L33/155
Filed: 2007-06-25
Abstract: Disclosed is an aqueous vitamin formulation comprising at least 10% by weight of water, at least 5% by weight of one or more vitamins, a castor oil alkoxylate with on average 15-25 moles of ethyleneoxy units per mole of castor oil alkoxylate, and optionally further additives. Also disclosed is the use of this formulation to add to animal feed or drinking water.
Patent NZ-574531-A (NZ)
Title: Device and method for determining the temperature inside an item to be cooked
Inventor: LUCKHARDT CHRISTOPH
IPC: F24C7/08
Filed: 2007-10-30
Abstract: A device and a method for determining the temperature inside an item to be cooked is disclosed. The device comprises at least one temperature sensor for detecting at least one surface temperature of the item to be cooked and/or an ambient temperature around the item to be cooked, at a location inside a cooking chamber surrounding the item to be cooked; at least one distance sensor capable of determining the distance between the distance sensor and one or multiple distance measuring points on the surface of the item to be cooked; at least one time measurement device for measuring elapsed time during preparation of the item to be cooked; and at least one calculation device for calculating the temperature inside the item to be cooked using the surface temperature of the item to be cooked and/or the ambient temperature, the distance or multiple distances, the elapsed time, and the start temperature of the item to be cooked.
Patent NZ-577969-A (NZ)
Title: Connector joining planar building elements allowing movement in one direction within the plane of the elements
Inventor: BANKS GEOFFREY NIGEL
IPC: F16B3/00
Filed: 2009-06-24
Abstract: A retention device (1) that is useful for concrete elements or with construction elements of other rigid materials is disclosed. The device (1) is attached to two adjacent construction elements (60, 61) that restricts out of plane movement between said elements. The device (1) includes at least one finger(4,5,6,7), zero or more slots(8,9) and zero or more notches (10,11) such that each finger (4,5,6,7) is a strip of material configured to slidingly engage with a notch (10,11) or slot (8,9) in at least one other connector(2,3). The connector (2, 3) is configured to be attached to a construction element (60, 61) by a single connection.
Patent NZ-579549-A (NZ)
Title: Co-production of power and hydrocarbons
Inventor: BOSHOFF JAN HENDRIK DUVENHAGE
IPC: C10G2/00
Filed: 2008-02-08
Abstract: Disclosed is a process for co-producing power and hydrocarbons, the process including; gasifying coal to produce a synthesis gas and a combustion gas both comprising at least CO, H2 and CO2 and being at elevated pressure; separating CO2 from the synthesis gas; synthesizing hydrocarbons from the synthesis gas; generating power from the combustion gas, including combusting the combustion gas in the presence of oxygen and in the presence of at least a portion of said separated CO2 as moderating agent to produce a combusted gas which includes CO2; and recovering or recycling the C02 from the combusted gas or a gas derived therefrom.
Patent NZ-585856-A (NZ)
Title: Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
Inventor: LAMARCA CASADO ROSA
IPC: A61K9/14
Filed: 2009-03-13
Abstract: Disclosed herein is a pharmaceutical composition for inhalation comprising aclidinium in the form of a dry powder of a pharmaceutically acceptable salt in admixture with a pharmaceutically acceptable dry powder carrier, providing a metered nominal dose of aclidinium equivalent to about 200 micrograms aclidinium bromide, said compositions can further comprise an effective amount of one or more addititional active agents selected from beta2-agonists, PDE IV inhibitors and corticosteroids. Also disclosed is the use of aclidinium in free or pharmaceutically acceptable salt form in the manufacture of a medicament for treating a respiratory condition selected from asthma and chronic obstructive pulmonary disease in a patient in need of such treatment, said use comprising administering a single or twice daily metered nominal dose of aclidinium equivalent to about 200 micrograms aclidinium bromide.
Patent NZ-589636-A (NZ)
Title: Pharmaceutical composition comprising extracts of huanglian and ku ding cha effective for lowering blood lipid levels
Inventor: SHAN JACQUELINE JIE
IPC: A61K36/718
Filed: 2009-05-01
Abstract: Disclosed is a synergistic composition for managing blood lipid levels, wherein said composition comprises a) a first active ingredient selected from the group consisting of Huanglian, Huanglian extracts, berberine and berberine containing plant extracts (such as those obtained from Coptis chinensis Franch, Coptis deltoidea, Coptis teeta Wall or Hydrastis Canadensis); and b) a second active ingredient selected from the group consisting of Ku Ding Cha and Ku Ding Cha extracts (such as those obtained from Ilex kudincha (Aquifoliaceae), ilex aquifoliacese, ilex latifolia, Ligustrum robustum, Ehretia thyrsiflora, Clerodendrum fortunatum or Ilex cornuta), wherein the weight ratio of parts a) to b) is between about 10% and 90%.