baber/WOPTO huggingface dataset:
Patent WO-2022071953-A1 (WO)
Inventor: BASHIR ALI
IPC: C12Q1/6806
Filed: 2020-10-01
Abstract: Contemporary gene sequencing techniques, including "Next Generation Sequencing" techniques, can include sequencing a plurality of fragments of a target polynucleotide. These fragment sequences are then used to determine a sequence for the target as a whole. This can include aligning the fragment sequences to each other anchor to a reference genome. However, the limitations of existing sequencing techniques, and the often repetitive or otherwise difficult-to-sequence structure of natural polynucleotides, means that it can be difficult and/or expensive to generate accurate sequences. Methods provided herein include inserting polynucleotide 'barcodes' into a target polynucleotide prior to fragmentation or other sequencing processes. These inserted barcodes can improve the accuracy of sequences generated for the target by adding 'noise' into the target, allowing subsequent sequencing techniques (e.g., alignment, stitching, etc.) to more accurately estimate the target-plus-barcodes sequence. The barcodes can then be removed to provide the sequence of the target polynucleotide.
Patent WO-2021067751-A1 (WO)
Inventor: CHARLESWORTH JONATHAN
IPC: A61N1/36
Filed: 2020-10-02
Abstract: Systems and methods for treating a patient having symptoms of restless legs syndrome (RLS) or Periodic Limb Movement Disorder (PLMD) using high-frequency stimulation by applying a high-frequency pulsed electrostimulation therapy signal to a peroneal nerve or a branch thereof, where the therapy signal is above a motor threshold of a muscle innervated by the peroneal nerve or branch thereof. Surface EMG (sEMG) response to neurostimulation can be used to evaluate patient responsivity to neurostimulation, or to evaluate neurostimulation efficacy, such as to compare various neurostimulation parameter settings and to select between such settings to meet or balance between one or more goals. The sEMG response can be obtained with the muscle at rest, or during muscle activation.
Patent WO-2021091989-A1 (WO)
Title: System and method for precise vehicle positioning using bar codes, polygons and projective transformation
Inventor: STONE JONATHAN
IPC: G01B11/26
Filed: 2020-11-04
Abstract: A disclosed vehicle positioning system includes a camera disposed on a vehicle for reading an optic label disposed on fixed object and for obtaining an image of a polygonal shape also disposed on the fixed object and a controller operable to determine a distance and orientation of a focal point relative to the fixed object based on perspective dimensions of the polygonal shape captured by the camera and actual dimensions of the polygonal shape read from the optic label.
Patent WO-2021137962-A1 (WO)
Title: Method and apparatus for coding video data in palette mode
Inventor: SARWER MOHAMMED
IPC: H04N19/50
Filed: 2020-11-17
Abstract: The present disclosure provides apparatuses and methods for performing palette coding of video data. According to certain disclosed embodiments, the methods include: determining whether a luma component of a coding unit (CU) and chroma components of the CU are coded jointly or separately in a palette mode; and in response to the luma component and the chroma components being coded jointly in the palette mode, determining a first maximum palette-table size for the CU; determining a first maximum palette-predictor size for the CU; and predicting the CU based on the first maximum palette-table size and the first maximum palette-predictor size.
Patent WO-2021102252-A1 (WO)
Inventor: NIJASURE MANGESH P
IPC: G06F9/455
Filed: 2020-11-20
Abstract: A graphics processing unit (GPU) [102] adjusts a frequency of clock based on identifying a program thread [104, 106] executing at the processing unit, wherein the program thread is detected based on a workload [116, 117] to be executed. By adjusting the clock frequency based on the identified program thread, the processing unit adapts to different processing demands of different program threads. Further, by identifying the program thread based on workload, the processing unit adapts the clock frequency based on processing demands, thereby conserving processing resources.
Patent WO-2021119116-A1 (WO)
Inventor: CANDELARIA ADRIAN
IPC: H01R4/18
Filed: 2020-12-09
Abstract: A tap connector for piercing an insulation of a conductor is provided. The tap connector includes a first jaw, a second jaw, a hinged connection, a compression connection, and a piercing insert. The hinged connection connects an end of the first and second jaws to one another. The compression connection removably connects an opposite end of the first and second jaws to one another. The piercing insert depends from the first jaw in an electrically conductive manner between the end and the opposite end. The piercing insert and the first jaw are made of or at least coated with an electrically conductive material.
Patent WO-2021119395-A1 (WO)
Inventor: KARSHMER DAVID
IPC: A61B5/097
Filed: 2020-12-11
Abstract: Provided herein are systems and methods configured for the collection of breath samples to allow for the detection of respiratory and systemic infections in a subject (e.g., a human patient) in conjunction with delivery of a drug to the subject. The drug may be configured t be metabolized by putative urease pathogens colonizing and/or infecting the subject. The metabolism of the drug by the putative urease pathogens produces elevations in the abundance of 13C02 in the patient's breath samples. Further, the described systems and methods involve collection of one or more baseline breath sample before introduction of the drug into the subject's respiratory airway, as well as one or more breath samples collected a selected period or periods after the completion of the drug delivery. Comparing the abundance o 13C02 in the post-administration sample(s) to the abundance of 13C02 in the baseline sample(s) allows for the detection of urea metabolizing infections of interest.
Patent WO-2021119638-A1 (WO)
Inventor: NORBY VIBHU
IPC: G06Q50/10
Filed: 2020-12-14
Abstract: Techniques for tracking a product at a retail location, monitoring a consumer at the retail location, managing product interaction at a physical display of the retail location, managing product interaction at an electronic kiosk of the retail location, and generating attributable interest. The electronic kiosk can be implemented as a smart mirror, a customized fitting room, a photo booth, an amusement park kiosk, a tablet computer, or the like. Attributable interest can be explicit for a potential consumer, such as a profile associated with a person for whom personally identifying information is known; a persona, such as a type of person for which demographic, psychographic, behavioristic, geographic, or other information is known; or a statistical potential consumer that incorporates advertising exposure, social interest, or the like into a probability score.
Patent WO-2021158312-A1 (WO)
Title: In ear device customization using machine learning
Inventor: Khaleghimeybodi Morteza
IPC: H04R1/10
Filed: 2020-12-25
Abstract: A design system generates a design for an in-ear device customized for a user. The in-ear device produces audio content for the user. The design system captures anthropometric data of the user. Using machine learning techniques, the design system determines features of an ear of the user from the anthropometric and generates a three dimensional (3D) geometry of the user's ear. A design for the in-ear device is generated based on the 3D geometry of the user's ear and includes a shell configured to fit in at least a portion of an ear canal of the user.
Patent WO-2021183218-A1 (WO)
Inventor: KADOCH CIGALL
IPC: A61P35/00
Filed: 2021-01-21
Abstract: La présente invention est basée, en partie, sur l'identification d'une région minimale de l'oncoprotéine de fusion SS18-SSX qui induit une interaction directe, à haute affinité entre le complexe mSWI/SNF et le patch acide de nucléosome et concerne des procédés et des agents de modulation de l'interaction entre la protéine de fusion SS18-SSX et les nucléosomes marqués par H2A K119Ub pour traiter le sarcome synovial.
Patent WO-2021150921-A1 (WO)
Title: Open view, multi-modal, calibrated digital loupe with depth sensing
Inventor: HEGYI ALEX
IPC: H04N13/332
Filed: 2021-01-22
Abstract: A digital loupe system is provided which can include a number of features. In one embodiment, the digital loupe system can include a stereo camera pair and a distance sensor. The system can further include a processor configured to perform a transformation to image signals from the stereo camera pair based on a distance measurement from the distance sensor and from camera calibration information. In some examples, the system can use the depth information and the calibration information to correct for parallax between the cameras to provide a multi-channel image. Ergonomic head mounting systems are also provided. In some implementations, the head mounting systems can be configurable to support the weight of a digital loupe system, including placing one or two oculars in a line of sight with an eye of a user, while improving overall ergonomics, including peripheral vision, comfort, stability, and adjustability. Methods of use are also provided.
Patent WO-2021154637-A1 (WO)
Title: Servicing concurrent queries via virtual segment recovery
Inventor: Kondiles George
IPC: G06F11/14
Filed: 2021-01-25
Abstract: A method for execution by a node of a computing device includes determining a plurality of queries for concurrent execution. A plurality of sets of segments required to execute the plurality of queries is determined, and a set of virtual segments in the plurality of sets of segments is determined. A subset of the set of virtual segments is be determined by identifying ones of the set of virtual segments that are required to execute multiple ones of plurality of queries. A locally rebuilt set of rows for each of the set of virtual segments is generated by utilizing a recovery scheme. For each one of the set of virtual segments included in the subset, in response to generating the locally rebuilt set of rows, concurrent partial execution of corresponding multiple ones of the plurality of queries is facilitated.
Patent WO-2021163320-A1 (WO)
Title: Soft orthopedic anchor assembly and instruments for inserting same
Inventor: SNELL DOUGLAS
IPC: A61F2/08
Filed: 2021-02-11
Abstract: An orthopedic anchor assembly may include an elongate, relatively soft orthopedic anchor; and a suture strand extending from a first end of the orthopedic anchor through a sidewall of the orthopedic anchor and internally through the orthopedic anchor to a second end of the orthopedic anchor. The suture strand may further extend through the sidewall of the orthopedic anchor at the second end of the orthopedic anchor and extend back to the first end of the orthopedic anchor externally to the orthopedic anchor.
Patent WO-2021173412-A1 (WO)
Inventor: KIM YOUNG SHIN
IPC: H05K3/00
Filed: 2021-02-18
Abstract: A circuit structure that comprises a substrate and one or more conductive elements disposed on the substrate is provided. The substrate comprises a polymer composition that comprises an electrically conductive filler distributed within a polymer matrix. The polymer matrix contains at least one thermoplastic high performance polymer having a deflection under load of about 40°C or more as determined in accordance with ISO 75-2:2013 at a load of 1.8 MPa, and the polymer composition exhibits a dielectric constant of about 4 or more and a dissipation factor of about 0.3 or less, as determined at a frequency of 2 GHz.
Patent WO-2021178238-A1 (WO)
Inventor: ZINN ALFRED A
IPC: H05K1/02
Filed: 2021-02-26
Abstract: Printed circuit boards may be formed using ceramic substrates with high thermal conductivity to facilitate heat dissipation. Metal nanoparticles, such as copper nanoparticles, may be used to form conductive traces and fill through-plane vias upon the ceramic substrates. Multi-layer printed circuit boards may comprise two or more ceramic substrates adhered together, wherein each ceramic substrate has one or more conductive traces defined thereon and the one or more conductive traces are formed through consolidation of metal nanoparticles. The one or more conductive traces in a first ceramic substrate layer are in electrical communication with at least one second ceramic substrate layer adjacent thereto.
Patent WO-2021178857-A1 (WO)
Title: Inhibiteurs de stat à substitution alpha et compositions de ceux-ci
Inventor: FLECK ROMAN
IPC: C07C311/14
Filed: 2021-03-05
Abstract: L'invention concerne des composés et des compositions pharmaceutiques comprenant lesdits composés qui sont utiles pour l'inhibition du transducteur de signal et de l'activateur de transcription 5a et 5b (STAT5). En outre, les composés et compositions de l'invention sont utiles pour le traitement du cancer, tel que, par exemple, le cancer du sein et le cancer du pancréas.
Patent WO-2021183638-A1 (WO)
Title: Pressure modulated motor torque for infusion pump
Inventor: MADDEN HENRY
IPC: A61M5/172
Filed: 2021-03-10
Abstract: An infusion pump can be configured to modulate a drive motor based on perceived infusion pressure requirements for quieter, more energy-efficient operation of the drive motor. The infusion pump can include an electrical motor having a variable output torque based on the electrical current input, a plunger head sensor configured to detect a force between a plunger driver and a plunger of a medicament container, and a control module configured to regulate the electrical current input to the electrical motor based on the detected force between the plunger driver and the plunger medicament container. The electrical current input for such an infusion pump can be incrementally reduced according to defined magnitudes of detected force.
Patent WO-2021207523-A1 (WO)
Inventor: LEON GUSTAVO
IPC: B65F1/00
Filed: 2021-04-08
Abstract: Disclosed is a waste container, liner, and rail system. The system may include one or more waste containers or one or more basketless systems or liner receivers to direct, hold, and facilitate the sequential replacement of a waste liner. The system may comprise a pull out track system that is adaptable to cabinetry or another defined space for a waste container. The pull out track system may generally include front, rear, side, and/or base panels, as well as at least one internal panel. The at least one internal panel may define an interior space configured to receive waste liners and to dispense the waste liners automatically.
Patent WO-2021216432-A1 (WO)
Inventor: WEINBERG BRETT
IPC: A23K20/174
Filed: 2021-04-19
Abstract: A dog chew is described made from plant-based ingredients (excluding the common allergens, corn, wheat, soy and gluten) and binding agents (such as bone-based gelatins, humectants and preservatives), coated with a flavored material (such as poultry, meat or fish and other flavorings), and being entirely free from commonly used poorly digestible ingredients (such as rawhide, reconstituted rawhide, synthetic materials and gums).
Patent WO-2021225908-A1 (WO)
Title: Triple combination therapy for enhancing cancer cell killing in cancers with low immunogenicity
Inventor: MOHANLAL RAMON
IPC: A61K39/395
Filed: 2021-04-30
Abstract: Disclosed herein are composition and methods of treating a condition where enhanced immunogenicity is desired. Some embodiments disclosed herein relate to compositions comprising a T-cell activator and/or proliferator, one or more immune checkpoint inhibitor, and a FPPS inhibitor. Some embodiments relate to methods of treating cancer by co-administering plinabulin, one or more immune checkpoint inhibitor, and a FPPS inhibitor to a subject in need thereof.
Patent WO-2021236534-A1 (WO)
Title: Resonant sensor reader
Inventor: REUEL NIGEL F
IPC: A61B5/00
Filed: 2021-05-17
Abstract: A system for reading at least one wireless resonant sensor includes a signal parameter measuring device, a reader housing, a computing device electrically connected to the signal parameter measuring device, and a plurality of reader antennas disposed within the reader housing and electrically connected to the signal parameter measuring device, wherein the plurality of reader antennas comprises a first reader antenna for signal output and a second reader antenna for signal input. The signal parameter measuring device is configured to sweep frequencies over a range of frequencies to acquire signal parameters for the wireless resonant sensor. The computing device is configured to determine changes in resonant frequency of the wireless resonator sensor based on the signal parameters. The reader housing may be sized and shaped for placement against a surface of a vessel in which a chemical or biological process is occurring.
Patent WO-2021236580-A1 (WO)
Title: Wireless node self-interference measurements and uplink beam management for full duplex transmissions
Inventor: ZHANG QIAN
IPC: H04B7/08
Filed: 2021-05-18
Abstract: Various aspects of the present disclosure generally relate to wireless communication. In some aspects, a first wireless node may determine, from a plurality of beams associated with the first wireless node, a set of suitable uplink beams and a set of suitable downlink beams, wherein the set of suitable UL beams and the set of suitable DL beams are suitable for full duplex communications, and transmit, to a second wireless node, an indication of the set of suitable uplink beams and the set of suitable downlink beams. Numerous other aspects are provided.
Patent WO-2021236817-A1 (WO)
Title: Restrict data access based on cellular network
Inventor: STRAND TERJE
IPC: H04W48/04
Filed: 2021-05-19
Abstract: Technologies are described for restricting access within a cellular telecommunications environment. For example, the technologies described herein can be used to allow cellular devices to connect to cellular networks even when the cellular networks are disallowed. However, the connections to cellular networks that are disallowed can be handled differently from connections to cellular networks that are allowed. For example, when a cellular device is allowed to connect to a disallowed cellular network, the connection can be directed to a particular packet data network gateway (PGW), such as a blocked PGW.
Patent WO-2021262931-A1 (WO)
Inventor: CHUA YING XUAN
IPC: C12N5/00
Filed: 2021-06-24
Abstract: The present disclosure is directed to devices used for transplanting or recruiting cells, in addition to methods for making said devices and for using said devices in the treatment of medical disorders.
Patent WO-2022046274-A1 (WO)
Title: Préparation de produit d'étanchéité à base de silicone
Inventor: SEITZ AARON
IPC: C08G77/18
Filed: 2021-06-28
Abstract: L'invention concerne un procédé de préparation d'une composition monoconstituant à fonction alcoxy vulcanisable à température ambiante (RTV), durcie avec un catalyseur à base d'étain. La composition d'agent d'étanchéité à base de silicone est conçue pour des compositions comprenant un polymère de polydiorganosiloxane à extrémité coiffée d'alcoxy, une charge, un agent de réticulation et un catalyseur à base d'étain et le procédé est conçu pour permettre un traitement in situ de charges tout en cherchant à réduire la présence de capteurs de groupe-OH dans la composition, en particulier pendant le stockage.
Patent WO-2022010691-A1 (WO)
Title: Accessing a multi-level memory cell
Inventor: SARPATWARI KARTHIK
IPC: H01L45/00
Filed: 2021-06-29
Abstract: Methods, systems, and devices for accessing a multi-level memory cell are described. The memory device may perform a read operation that includes pre-read portion and a read portion to access the multi-level memory cell. During the pre-read portion, the memory device may apply a plurality of voltages to a plurality of memory cells to identify a likely distribution of memory cells storing a first logic state. During the read portion, the memory device may apply a first read voltage to a memory cell based on performing the pre-read portion. The memory device may apply a second read voltage to the memory cell during the read portion that is based on the first read voltage. The memory device may determine the logic state stored by the memory cell based on applying the first read voltage and the second read voltage.
Patent WO-2022026774-A1 (WO)
Inventor: BEKAERT JEROEN
IPC: G01N33/68
Filed: 2021-07-29
Abstract: Provided are assays for functional immune assessment, immune element survey, and diagnostic methods using cultured cells. The immune functional assays enable assessment of subject immune function against a pathogen, utilizing antigen baits and target constructs. Bead based antigen baits provide a robust and facile method of assessing protective immune responses for pathogens, including systems for assessing immune function against SARS-CoV-2. Also provided are immune element surveys that enable profiling of immune elements deployed against a selected pathogen or antigen. Cell culture methods provide a novel and facile tool for assessment of immune function and diagnostic tools for detecting prior or current infection by pathogens. The assays may advantageously be combined for full spectrum analysis of a subjects immune response.
Patent WO-2022031910-A1 (WO)
Title: Providing a set of application slices within an application environment
Inventor: NAIR RAJ
IPC: G06N3/00
Filed: 2021-08-05
Abstract: Techniques manage cluster resources within an application environment. The techniques involve identifying a group of cluster resources from a plurality of cluster resources of the application environment, the plurality of cluster resources being constructed and arranged to provide a plurality of services. The techniques further involve forming an application slice having the group of cluster resources. The techniques further involve deploying the application slice to provide services. Certain techniques provide a platform that allows operators to build application slices (or application overlays) that are a way of grouping application pods (or containers) based on one or more organizing principles such as velocity of deployment, security, governance, etc.
Patent WO-2022032153-A1 (WO)
Title: Cell culture medium for use in producing gene therapy products in bioreactors
Inventor: MATHUR KRISHANU
IPC: C12N15/861
Filed: 2021-08-06
Abstract: The present disclosure describes methods and systems for use in the production of adeno- associated virus (AAV) particles, compositions, and formulations, including recombinant adeno-associated viruses (rAAV). The present disclosure presents cell culture mediums for use in producing adeno-associated viruses (AAV), such as AAV which comprise a polynucleotide encoding a payload. In certain embodiments, the cell culture medium comprises a hydrolysate mixture, L-glutamine, poloxamer 188 (e.g., 10% pluronic F-68), a lipid emulsion, and a cholesterol mixture. In certain embodiments, the production process and system use Spodoptera fmgiperda insect cells (such as Sf9 or Sf21) as viral production cells (VPCs). In certain embodiments, the production process and system use Baculo viral Expression Vectors (BEVs) and/or Baculoviral Infected Insect Cells (BIICs) in the production of rAAVs.
Patent WO-2022051324-A1 (WO)
Inventor: GANESAN RAGHU
IPC: H04L7/033
Filed: 2021-09-01
Abstract: An example apparatus (102) includes: a feed forward equalizer (FEE) (122) with a FFE output, adder circuitry (124) with a first adder input, a second adder input, and a first adder output, the first adder input coupled to the FFE output, a multiplexer (MUX) (126) with a first MUX input, a second MUX input, and a MUX output, the first MUX input coupled to the first adder output, the second MUX input coupled to the FFE output, a decision feedback equalizer (DFE) (130) with a DFE output coupled to the second adder input, and a timing error detector (TED) (136) with a first TED input coupled to the MUX output.