baber/WOPTO huggingface dataset:
Patent CA-3149872-A1 (CA)
Inventor: SWEET-CORDERO ERIC ALEJANDRO
IPC: A61K38/17
Filed: 2020-09-10
Abstract: L'invention concerne des méthodes de traitement d'un cancer mutant KRAS chez un individu. Dans certains modes de réalisation, les procédés comprennent l'administration, à un individu identifié comme ayant un cancer mutant KRAS, d'une quantité thérapeutiquement efficace d'un agent qui inhibe la signalisation de récepteur du facteur 1 de cytokine de type cardiotrophine (CLCF1) du facteur neurotrophique ciliaire (CNTFR). Selon certains modes de réalisation, le cancer mutant KRAS est un cancer du poumon mutant KRAS, tel qu'un cancer du poumon autre qu'à petites cellules (NSCLC) mutant KRAS, par exemple, un adénocarcinome pulmonaire (LUAD) mutant KRAS. L'invention concerne également des kits qui trouvent une utilisation, par exemple, dans la mise en ?uvre des méthodes de la présente invention.
Patent CA-3152246-A1 (CA)
Title: Gas ultrasonic transducer system and method for operating a diesel common-rail engine
Inventor: BONOMI ALBERTO
IPC: F02M21/04
Filed: 2020-05-21
Abstract: The invention relates to systems enabling use of liquefied petroleum gas in diesel common-rail engines, and in particular to fueling diesel engines with diesel gas dual-fuel or only gas instead of diesel fuel. A gas ultrasonic transducer system for operating a diesel common-rail engine, comprises an electronic control unit; a water tank; a gas tank with gas supply shut-off valve; a gas level sensor; a gas pump operably connected with the gas tank; a water pump operably connected with the water tank; a mixer comprising a water level sensor and an ultrasonic transducer adapted to generate water vapor and gas mixture; wherein the mixer comprises two compartments: the upper compartment and the lower compartment, the means for separation of the upper and the lower compartments comprising an anti-reflux valve adapted to allow water vapor from the lower compartment to pass through the anti-reflux valve to the upper compartment and to prevent any liquid water from flowing into the upper compartment; wherein the upper compartment of the mixer comprises an outlet operably connected with engine intake manifold; wherein the outlet of the gas pump is operably connected with the upper compartment of the mixer, the outlet of the water pump is operably connected with lower compartment of the mixer, where the ultrasonic transducer is located below the anti-reflux valve. The controlled interaction between elements of the system and vehicle elements results in a gas-water vapor mixture. In case of embodiment with dual fuel, the water gas mixture is calculated on the grounds of information received by the electronic control unit of the system from the engine common-rail, the engine temperature sensor, the air flow meter sensor, the acceleration pedal block.
Patent CA-3153600-A1 (CA)
Inventor: DUAN WENHU
IPC: C07D401/14
Filed: 2020-09-03
Abstract: A compound having Axl and c-Met kinase inhibitory activity, a preparation method therefor and an application thereof. Specifically, a compound having the structure represented by formula (I), a preparation method therefor and an application thereof in the preparation of a medication for the treatment and/or prevention of tumor-associated diseases and/or kinase-related diseases.
Patent CA-3156606-A1 (CA)
Title: Controllable differential system and vehicle having the controllable differential system
Inventor: BEN ATTOUCH WALID
IPC: B60K17/34
Filed: 2020-10-30
Abstract: A controllable differential system for a vehicle includes a differential that may be disengaged or engaged, and may further be locked when engaged. A differential lock switch has three positions for sending commands to an actuator for disengaging or engaging the differential and for sending commands to a controller for unlocking and locking the differential. The vehicle includes a motor, a transmission continuously connected to a rear drivetrain, and the differential mounted in a front drivetrain. The vehicle may be driven in rear-wheel drive mode when the differential is disengaged or in four-wheel drive mode when the differential is engaged. The vehicle may enforce a vehicle speed limitation or an engine speed limitation when the differential is locked while a manual override control is not activated. The vehicle may implement an anti-lock braking system that may be disabled when the differential is locked.
Patent CA-3156936-A1 (CA)
Title: Configuration d'occasions de surveillance de signal d'economie d'energie et signalisation de capacite
Inventor: MALEKI SINA
IPC: H04W72/04
Filed: 2020-11-06
Abstract: La consommation d'énergie de l'équipement d'un utilisateur est un paramètre qui doit être amélioré. Des techniques permettant de réduire une surveillance inutile d'un canal de commande de liaison descendante physique (PDCCH) ou de permettre à l'équipement d'un utilisateur de s'éteindre ou de s'allumer uniquement lorsqu'une telle manoeuvre est exigée sont souhaitables. Il existe cependant un certain nombre de défis rattachés aux détails des configurations sous-jacentes de l'occasion de surveillance, particulièrement en ce qui a trait au décalage et à la portée des configurations des signaux de réveil et d'un mode de signalisation d'économie d'énergie. Par exemple, certaines réalisations décrivent des mécanismes liés à la configuration des occasions de surveillance PSS et à la signalisation des capacités pour les PSS basés sur PDDCH, des mécanismes pour les configurations de décalage PSS avec et sans information d'assistance UE (ou signalisation de capacité UE), mécanismes pour les configurations de plage MO PSS avec et sans information d'assistance UE (ou signalisation de capacité UE), et des mécanismes pour le comportement UE à la réception d'une configuration MO PSS spécifique du noeud réseau.
Patent CA-3157629-A1 (CA)
Inventor: CARLSON TIMOTHY
IPC: A61K31/55
Filed: 2020-11-10
Abstract: Disclosed herein are methods of treatment comprising administering a therapeutically effective amount of a myosin modulator or a pharmaceutically acceptable salt thereof to a subject in need thereof and diagnostic methods useful in connection with those treatments. Due to observations unfolding in clinical trials with mavacamten and with mavacamten and other myosin inhibitors in the pre-clinical setting, new insights into how myosin inhibitors can be used beneficially to impact the disease state of HCM and other diseases are provided herein.
Patent CA-3158171-A1 (CA)
Title: Fenetre pour batiments civils et industriels
Inventor: ZANETTI MAURO
IPC: E06B7/02
Filed: 2020-10-14
Abstract: L'invention concerne une fenêtre (1) pour bâtiments civils et industriels, comprenant un cadre porteur (2) pour une paire de feuilles (3, 4) constituée d'un matériau optiquement transparent : une première feuille (3) et une seconde feuille (4) qui possèdent une face relative orientée, respectivement, vers l'extérieur et vers l'intérieur d'un bâtiment (9) sur lequel la fenêtre (1) est montée. L'invention concerne également des moyens (11, 12, 13) pour convertir l'énergie de la lumière solaire incidente en électricité, au moyen de l'effet photovoltaïque intercalé entre les feuilles (3, 4) mentionnées ci-dessus.
Patent CA-3158837-A1 (CA)
Inventor: LAUTENSCHLAGER JENS
IPC: B01J19/12
Filed: 2022-05-12
Abstract: Abstract The invention refers to a distillation apparatus (100) for extraction of volatile components from biological material (50), especially from plants, comprising a .. housing (10) defining a sample chamber (S), a drum (30) arranged in the sample chamber (S), the drum (30) defining a receiving chamber (R) for receiving the biological material (50), and at least one microwave generator (70) for irradiating the biological material (50) with microwave radiation when received in the drum (30); wherein the drum (30) is rotatably arranged in the sample chamber (S) about a rotation axis (H) which is oriented substantially horizontally. Date Recue/Date Received 2022-05-12
Patent CA-3166018-A1 (CA)
Inventor: TAZI JAMAL
IPC: C12Q1/6883
Filed: 2015-07-17
Abstract: There is provided an in vitro or ex vivo use of at least one miRNA being miR-124, as a biomarker for screening a compound of formula (I), presumed effective in treating and/or preventing an inflammatory disease (see formula I) wherein                                                        means an aromatic ring wherein V is C or N and when V is N, V is in ortho, meta or para of Z, i.e. forms respectively a pyridine, a pyridazine, a pyrimidine or a pyrazine group, Q is N or O, provided that R" does not exist when Q is O, R' independently represent a hydrogen atom or a group chosen among a (C1-C3)alkyl group, a halogen atom, a ¨NO2 group, a -NR1R2 group, a morpholinyl group, a morpholino group, a N-methylpiperazinyl group, a (C1-C3)fluoroalky I group, a -O-P(=O)-(OR3)(0R4) group and a ¨CN group, and can further be a group chosen among: (see formula IIa)(see formula IIIa) or anyone of its pharmaceutically acceptable salt.
Patent CA-3167111-A1 (CA)
Title: Traitement de maladies associees au panx1
Inventor: KHALDI NORA
IPC: A61K38/08
Filed: 2021-02-08
Abstract: Les inventeurs ont découvert que le peptide de SEQ ID NO : 1 (WKDEAGKPLVK) cible PANX1. L'invention concerne également le traitement de maladies associées au PANX1 avec le peptide ou une composition comprenant le peptide.
Patent CA-3167763-A1 (CA)
Title: Ergonomics improvement systems having wearable sensors and related methods
Inventor: GEORGESON GARY E
IPC: G08B21/02
Filed: 2022-07-14
Abstract: Wearable ergonomics improvement systems and related methods are disclosed. An example ergonomics improvement system includes a membrane including a first frame having a plurality of first cutouts defining a first pattern. The system includes a sensor coupled to the membrane and includes a second frame having a plurality of second cutouts defining a second pattern. The first pattern is complementary to the second pattern.
Patent CA-3167923-A1 (CA)
Inventor: SCHMIDT ROBERT KYLE
IPC: B64C25/10
Filed: 2021-02-18
Abstract: A bushing is configured for installation in the hole of a lug, which has a protrusion extending radially inward from a surface of the hole. The bushing includes a first cylindrical body that is sized to be received within the hole of the lug. A flange extends radially outward from one end of the first cylindrical body, and a first recess is formed in the first cylindrical body to a radial face. The recess is sized and configured to receive the protrusion of the lug when the bushing is installed in the hole. Engagement of the protrusion with the recess preventing movement of the bushing relative to the lug.
Patent CA-3171831-A1 (CA)
Title: Propionibacterium acnes prophylactic and therapeutic immune treatment
Inventor: SELAK SANJA
IPC: A61K39/00
Filed: 2021-02-22
Abstract: The present invention discloses a vaccine comprising one or more of Dermatan sulfate-binding adhesin 1 of P. acnes (DsA1 polypeptide), Dermatan sulfate-binding adhesin 2 of P. acnes (DsA2 polypeptide), and putative iron-transport protein (PITP) polypeptide of P. acnes, and/or a fragment and/or derivative of DsA1 and/or DsA2 and/or PITP, wherein the DsA1 polypeptide and the DsA2 polypeptide comprise from N- to C-terminus an N-terminal swapping region ("NSR"), a first conserved sub-domain ("CSD1"), a first swapping region ("SR1"), a second conserved sub-domain ("CSD2"), a second swapping region ("SR2"), a third conserved sub-domain ("CSD3"), a Pro-Thr repeat containing region ("PT repeat region"), and a C-terminal region ("CTR"), and wherein the PITP polypeptide comprises from N- to C-terminus an extended neocarzinostatin family domain ("ENFD"), a first swapping region ("SR1"), a heme¬ binding domain ("HbD"), a second swapping region ("SR2") including the C-terminal LPXTG motif, and a hydrophobic C-terminal region ("hLAR").
Patent CA-3172956-A1 (CA)
Inventor: HARRISON STEPHEN
IPC: C01D15/08
Filed: 2011-02-17
Abstract: The invention generally relates to methods of selectively removing lithium from various liquids, methods of producing high purity lithium carbonate, methods of producing high purity lithium hydroxide, and methods of regenerating resin.
Patent CA-3177838-A1 (CA)
Title: Systems and methods for processing objects including mobile matrix carrier systems
Inventor: WAGNER THOMAS
IPC: B65G1/04
Filed: 2018-03-20
Abstract: A storage, retrieval and processing system for processing objects is disclosed. The storage, retrieval and processing system includes a plurality of storage bins providing storage of a plurality of objects, where the plurality of storage bins is in communication with a bin conveyance system for moving selected storage bins to a storage bin processing location, a programmable motion device in communication with the bin processing location for receiving a selected storage bin from the plurality of bins, where the programmable motion device includes an end effector for grasping and moving a selected object out of a selected storage bin, and a plurality of destination bins in communication with the bin conveyance system for moving a selected destination bin from a destination bin processing location that is proximate the programmable motion device to the plurality of destination bins.
Patent CA-3178374-A1 (CA)
Inventor: CONNELL ROBERT
IPC: A61B5/145
Filed: 2021-05-26
Abstract: Un dispositif de détection transdermique de concentration d'une ou de plusieurs substances dans la circulation sanguine d'un sujet est divulgué. Le dispositif comprend un module de génération de signal conçu pour générer des signaux de fréquence micro-onde à une ou plusieurs fréquences discrètes. Le dispositif comprend également un module de capteur comprenant au moins un capteur de résonance de micro-ondes agencé pour entrer en contact avec la peau d'un sujet, le ou les capteurs de résonance de micro-ondes étant agencés pour émettre des signaux de fréquence micro-onde générés par le module de génération de signal dans le corps du sujet. Le dispositif comprend également un module de traitement de signal connecté au ou aux capteurs de résonance de micro-ondes et agencé pour : détecter une caractéristique de résonance du ou des capteurs de résonance de micro-ondes, et traiter la caractéristique de résonance pour déterminer la concentration d'une ou de plusieurs substances dans la circulation sanguine d'un sujet.
Patent CA-3179562-A1 (CA)
Title: An ion shutter, a method of controlling ion shutter, and detection methods and apparatus
Inventor: ARNOLD PAUL
IPC: H01J49/06
Filed: 2021-05-27
Abstract: A method of operating an ion mobility spectrometer comprises the following steps: drawing a sample of gaseous fluid into a reaction region of the ion mobility spectrometer; providing a first pulse of a pulsed ionisation source to ionise the sample of gaseous fluid, thereby to obtain first sample ions; after a first gate delay following the first trigger opening an ion shutter to permit a portion of the first sample ions to leave the reaction region; providing a second pulse of the pulsed ionisation source to further ionise the sample of gaseous fluid, thereby to obtain second sample ions; after a second gate delay following the first trigger opening the ion shutter to permit a portion of the second sample ions to leave the reaction region, wherein the second gate delay is different from the first gate delay.
Patent CA-3179737-A1 (CA)
Inventor: MEYERS SCOTT
IPC: G03B21/00
Filed: 2022-10-25
Abstract: A light assembly haying a projector integrally connected to a light bar. The projector and the light bar share power and control wires from a wire harness. The projector includes a projector aperture whereby light (oftentimes in a pattern or logo formation) passes therethrough and directs onto a ground surface. The projector includes a light assembly configured to hold the components for projection.
Patent CA-3183173-A1 (CA)
Inventor: PILLIS JOSEPH WOODROW
IPC: F04C29/02
Filed: 2021-05-12
Abstract: Un ensemble amortisseur à film fluide (100) destiné à un compresseur (12) comprend un manchon d'amortisseur (112) conçu pour être disposé autour d'un arbre de rotor (72) du compresseur (12). Le manchon d'amortisseur (112) comprend une poche de seuil de pression (166) formée dans une circonférence interne (145) du manchon d'amortisseur (112). La poche de seuil de pression (166) est conçue pour recevoir un écoulement de lubrifiant (24) et pour mettre sous pression l'écoulement de lubrifiant (24) par l'intermédiaire de la rotation de l'arbre de rotor (72). Le manchon d'amortisseur (112) comprend un passage de sortie (142) s'étendant à partir de la poche de seuil de pression (166) jusqu'à une circonférence externe (134) du manchon d'amortisseur (112). L'ensemble amortisseur à film fluide (100) comprend également un logement de palier (110) disposé autour du manchon d'amortisseur (112) pour former un espace d'amortisseur (116) s'étendant entre la circonférence externe (134) du manchon d'amortisseur (112) et le logement de palier (110). L'espace d'amortisseur (116) est en communication fluidique avec le passage de sortie (142) et est conçu pour recevoir l'écoulement de lubrifiant (24) à partir de la poche de seuil de pression (166).
Patent CA-3183453-A1 (CA)
Title: Robotic laundry devices and methods of use
Inventor: BIXBY BENJAMIN D
IPC: D06F95/00
Filed: 2021-05-27
Abstract: Devices, systems, and methods for repositioning a deformable laundry article are described. For example, a robotic device includes a conveyor (6030) configured to transfer the deformable laundry article outside of a work volume (6035), two or more lifters (6100a-d) including grippers (6105a-d) individually anchored about the perimeter of the work volume, two or more sensors (6128a-d) disposed at fixed locations about the work volume, and a memory storing data indicative of repositioned deformable laundry articles. A controller (6005) is in operative communication with the memory, the two or more sensors, and the two or more lifters. The controller is configured to receive a signal from the sensors, identify grip points on the deformable laundry article suspended above the conveyor, instruct a lifter to grip and lift an identified grip point to the suspension height, determine whether the deformable laundry article is repositioned, and instruct the lifters to lower the repositioned deformable laundry article onto the conveyor.
Patent CA-3184143-A1 (CA)
Title: Fluffing and styling nozzle and hair dryer
Inventor: ZHANG HAO
IPC: A45D20/12
Filed: 2021-06-28
Abstract: A fluffing and styling nozzle and a hair dryer suitable for the fluffing and styling nozzle are provided. The fluffing and styling nozzle includes a diffusing shell (404), a mesh cylinder (405), a flow dividing platform (407), a baffle plate (408), a magnetic part supporting rib reverse side (409), a middle air outlet hole (4010) and an internal diffusing chamber (4011). The flow dividing platform (407) and the baffle plate (408) are arranged on the diffusing shell (404), the baffle plate (408) is arranged at the bottom of the flow dividing platform (407), and the baffle plate (408) and the magnetic part supporting rib reverse side (409) form a side surface gap flow channel. Gas flowing out of the fluffing and styling nozzle is from the middle air outlet hole (4010) and the side surface gap flow channel, gas flowing out of the middle air outlet hole (4010) enters the internal diffusing chamber (4011), gas flowing out of the side surface gap flow channel is guided by the baffle plate (408) to side surfaces and edges of the mesh cylinder (405), and gases flowing out of the two portions flow out uniformly through mesh openings of the mesh cylinder (405). The middle air outlet hole (4010) and surrounding air outlet gaps are provided for dividing gas, and the flow of the gas in each flow direction is controlled by adjusting the sizes of the middle air outlet hole (4010) and the surrounding air outlet gaps, so that air is output entirely and uniformly.
Patent CA-3186030-A1 (CA)
Title: Endoscopic system and methods having real-time medical imaging
Inventor: ZINGARETTI GABRIELE
IPC: G06T15/20
Filed: 2021-06-24
Abstract: Systems and methods for improving endoscopy procedures are described that provide not only a conventional real time image of the view obtained by an endoscope, but in addition, a near real time 3D model and/or a 2D flattened image of an interior surface of an organ, which model and image may be processed using AI software to highlight potential tissue abnormalities for closer examination and/or biopsy during the procedure. A navigation module interacts with other system outputs to further assist the endoscopist with navigational indicia, e.g., landmarks and/or directional arrows, that enhance the endoscopists' spatial orientation, and/or may provide navigational guidance to the endoscopist to assist manipulation of the endoscope.
Patent CA-3190570-A1 (CA)
Title: Procede et appareil de commande de gestion d'energie pour vehicule et support de stockage lisible
Inventor: CHEN ZHILE
IPC: B60L58/12
Filed: 2021-08-25
Abstract: Il est décrit un procédé et un appareil de commande de gestion d'énergie pour un véhicule et un support de stockage lisible qui sont utilisés pour résoudre le problème du faible taux de réussite du démarrage du moteur d'un véhicule qui résulte en un risque relativement élevé de panne de ce dernier. Le procédé de commande de gestion d'énergie comprend : l'acquisition de la température ambiante prédite minimale dans une période prédéfinie; la détermination de la température ambiante minimale en fonction de la température ambiante prédite minimale et de la température ambiante actuelle; si la température ambiante minimale est inférieure ou égale à une première valeur seuil de température prédéfinie, la détermination d'un point de gestion de puissance minimale d'une batterie de traction en fonction de la température ambiante minimale; et la réalisation d'une commande de gestion d'énergie forcée sur un véhicule en fonction du point de gestion d'énergie minimale de sorte que l'énergie restante de la batterie de traction n'est pas inférieure au point de gestion d'énergie minimale.
Patent CA-3193037-A1 (CA)
Title: Pipelines de traitement d'image ou de video de camera avec incorporation neuronale
Inventor: GORDON KEVIN
IPC: G06N3/08
Filed: 2021-08-27
Abstract: Pipeline de traitement d'image comprenant un appareil photo ou une caméra vidéo comprenant une première partie d'un système de traitement d'image conçue pour utiliser des informations dérivées au moins en partie d'une incorporation neuronale. Une seconde partie du système de traitement d'image peut être utilisée pour modifier au moins l'un parmi un réglage de capture d'image, un traitement de capteur, un post-traitement global, un post-traitement local et un post-traitement de portefeuille, sur la base, au moins en partie, d'informations d'incorporation neuronale.
Patent CA-3196304-A1 (CA)
Inventor: MEERSSEMAN LAURENT
IPC: B44C5/04
Filed: 2021-11-04
Abstract: La présente invention concerne un panneau de plancher et un procédé de fabrication d'un panneau de plancher. Le panneau de plancher (10) comprend un substrat (20), une couche décorative (22) et un composant transparent (24). La couche décorative (22) est positionnée entre le substrat (20) et le composant transparent (24). Au moins l'un du substrat (20), de la couche décorative (22) et du composant transparent (24) comprend un matériau synthétique thermoplastique. Le composant transparent (24) a une surface supérieure (30) opposée à la couche décorative (22). Le panneau de plancher (10) comprend en outre un composant d'amélioration (32), le composant d'amélioration (32) étant disposé sur la surface supérieure (30) du composant transparent (24). L'épaisseur du composant d'amélioration (32) varie le long d'une section transversale du panneau de plancher (10).