baber/WOPTO huggingface dataset:
Patent JP-2017092294-A (JP)
Title: Imprinting device, mold, and manufacturing method for article
Inventor: KOMAKI TAKAMITSU
IPC: B29C59/02
Filed: 2015-11-12
Abstract: PROBLEM TO BE SOLVED: To provide a mold or imprinting device that is advantageous in terms of accuracy in alignment.SOLUTION: A mold 2 used in imprinting device that forms a pattern of imprinting material cured on a base plate 1, comprises: a pattern part; and a pair of marks 4, i.e., a first mark used for alignment with the base plate 1 in a first direction and a second mark used for alignment with the base plate in a second direction orthogonal to the first direction. The one pair of marks 4 lie within a field of view of a detector 6. Of the one pair of marks 4, the first mark is disposed close to an edge of the pattern part in the first direction, or the second mark is disposed close to an edge of the pattern part in the second direction. Accordingly, light reflected from a peripheral part of each mark is prevented from being mixed into light reflected from the mark, thereby enabling highly accurate detection of the marks.SELECTED DRAWING: Figure 1
Patent JP-2017087615-A (JP)
Title: Tire production method and tire molding device
Inventor: NAKAGAWA AKIRA
IPC: B29C33/02
Filed: 2015-11-12
Abstract: PROBLEM TO BE SOLVED: To prevent rubber biting in a gap in the circumferential direction formed between a plurality of sectors molding the trad face of a tire.SOLUTION: Provided is a tire production device comprising: the first step where the inside of a die 2 for tire vulcanization containing an upper die 21, a lower die 22 and sectors 20 is disposed with a green tire GT in such a manner that the axial direction goes vertically, and the inner face is held with a bladder 13; the second step where, while heating the green tire GT, the upper die 21 and the sectors 20 are lowered, the sectors 20 are moved to the inside diameter side via the segment 14 with a jacket ring 15, and the die 2 for tire vulcanization is closed; and the third step where the die 2 for tire vulcanization is closed. In the second step, immediately before the die 2 for tire vulcanization is perfectly closed, an immediately stopping operation of temporarily stopping the movement operation of the sectors 20 to the inside diameter side is practiced.SELECTED DRAWING: Figure 1
Patent JP-2017089341-A (JP)
Title: Work machine operation device
Inventor: ANDO HIROAKI
IPC: G05G1/04
Filed: 2015-11-17
Abstract: PROBLEM TO BE SOLVED: To provide a front operation lever device of a work machine, which can improve an interlock operability of different operations while matching an operation direction of an operator and a driving direction of a work device.SOLUTION: A switch 33 is rotatably installed on a tip of a grip part 36, which covers at least a tip of a shaft 35 of a lever 32 that operates vertical motion of a work arm by fluctuating the lever along vertical direction. A rotary axis of the switch 33 is set along a direction oblique to the grip part 36. An interlock operability of different operations can be improved while matching an operation direction of the fluctuation in vertical direction of the lever 32 and the rotation of the switch 33 by an operator OP and a driving direction of the work device.SELECTED DRAWING: Figure 1
Patent JP-2017098116-A (JP)
Title: Lighting fixture and lighting unit
Inventor: KAKUNO YOSHINORI
IPC: F21V21/00
Filed: 2015-11-25
Abstract: PROBLEM TO BE SOLVED: To provide a lighting fixture whose design can be easily changed.SOLUTION: A lighting fixture 2 is arranged so as to be embedded in a through hole 6 of a ceiling 4, and comprises: a fixture body 8 including a flange part 20 arranged around the through hole 6; a support member 38 of which at least a part is detachably inserted between the flange part 20 and the ceiling 4; and a decorative member 40 arranged below the fixture body 8 by being supported by the support member 38.SELECTED DRAWING: Figure 1
Patent JP-2017076101-A (JP)
Title: Transfer device and image forming apparatus
Inventor: NAGATA ATSUSHI
IPC: G03G15/16
Filed: 2015-11-27
Abstract: PROBLEM TO BE SOLVED: To provide a transfer device that can satisfactorily transfer a toner image in a special color even with the use of a developer deteriorated over time.SOLUTION: An image forming apparatus 1 comprises an image forming unit 110S that forms a toner image in a special color (S), such as gold and silver, in addition to image forming units 110Y, M, C, and K that form toner images in process colors including yellow (Y), magenta (M), cyan (C), and black (K). The image forming apparatus 1 performs correction of gradually decreasing a primary transfer bias for a special color for transferring the toner image in a special color (S) to an intermediate transfer belt 131 in an S mode of performing image formation by using only a special color toner according to the degree of deterioration of a developer forming the toner image in a special color (S), and gradually increasing the primary transfer bias for a special color in an FCS mode of forming images with all colors.SELECTED DRAWING: Figure 7
Patent JP-2017095274-A (JP)
Title: Conveyance apparatus
Inventor: AMAMIYA KAZUYUKI
IPC: B65G47/46
Filed: 2015-11-27
Abstract: PROBLEM TO BE SOLVED: To provide an article interval shortening classification apparatus capable of greatly improving economic efficiency by enabling not only prevention of articles from damaging each other by contact but also controlling of a classification mechanism according to the lengths of the articles and a classification order through control of transferring and throwing of the articles to a conveyor while keeping a distance between a preceding article and a succeeding article as minimum as possible.SOLUTION: A conveyance apparatus according to the present invention is provided with: a load classification branch point information device; a loading device that transfers loads to a conveyor; means for determining the position of the load classification branch point of a preceding article with respect to the load classification branch point of a next load, namely, far, similar, near or not, according to the information of the load classification branch point information device; and load interval shortening means for optionally setting a distance from the rear end of the preceding load to the tip of the next load on the basis of the determination.SELECTED DRAWING: Figure 1
Patent JP-2017099218-A (JP)
Title: Rotary electric machine
Inventor: YAMAZAKI GO
IPC: H02K5/24
Filed: 2015-11-27
Abstract: PROBLEM TO BE SOLVED: To allow a large vibration damping effect to be exhibited even when the number of revolutions of a rotary electric machine varies.SOLUTION: A rotary electric machine includes: a cylindrical fixing/supporting member 10; a rotor 50 supported in a rotatable manner inside the fixing/supporting member 10; a non-uniform mass body 11 fixed to a prescribed position in a circumferential direction of the fixing/supporting member 10; and hood dampers 30 being disposed so as to be spaced apart from one another in the circumferential direction of the fixing/supporting member 10 with respect to the non-uniform mass body 11 and generating resistance force against movement in a radial direction of the fixing/supporting member 10. When angle coordinates are obtained in a rotation direction of the rotor 50 with a position in a circumferential direction of one non-uniform mass body 11 as an original point, positions in the angle coordinates of the hood dampers 30 fall within ranges of 15 to 35 degrees, 105 to 125 degrees, 195 to 215 degrees and 285 to 305 degrees.SELECTED DRAWING: Figure 1
Patent JP-2017100494-A (JP)
Title: Thin register for air conditioner
Inventor: SATO ASEI
IPC: F24F13/15
Filed: 2015-11-30
Abstract: PROBLEM TO BE SOLVED: To suppress a pressure loss with a simple structure.SOLUTION: A blowout port 43 of a retainer 10 forms a rectangular shape composed of a pair of long side portions 45 and a pair of short side portions 44. A member changing an angle α in regard to the short side portions 44 of conditioning air A1 blown out from the blowout port 43 is composed of a first fin 55, a second fin 61, and a barrel 65 which respectively extend along the long side portion 45. Fins 55, 61 are disposed in parallel with each other on an upstream side of each long side portion 45. The barrel 65 is equipped with a pair of main fins 67 separated from each other along the short side portion 44. Downstream portions 67b of both main fins 67 are separated in parallel from each other at an interval similar to an interval of both fins 55 and 61. Between an operating member operated when the angle α at which the conditioning air A1 blows out is changed, both fins 55 and 61, and the barrel 65, a transmission mechanism is provided, which tilts both fins 55 and 61, and the barrel 65 in direction opposite to each other according to the operation of the operating member.SELECTED DRAWING: Figure 19
Patent JP-2017100982-A (JP)
Title: Horticultural insecticide acaricide composition and method for using the same
Inventor: TANAKA RYOSUKE
IPC: A01P7/02
Filed: 2015-12-01
Abstract: PROBLEM TO BE SOLVED: To provide a new technique for efficiently controlling pests whose control is difficult or whose control is impossible by the conventional technique.SOLUTION: Provided is a method for using a horticultural insecticide acaricide composition characterized in that the effective amount of a horticultural insecticide acaricide composition containing pyflubumide or a mixture of pyflubumide and fenpyroximate, machine oil and one or more kinds of spiracles blockade agents selected from fatty acid glyceride, sorbitan fatty acid ester or the like as effective ingredients is directly treated to a pest, or to a crop in which a pest is inhabited, or peripheral soil or a culture carrier in which a crop grows.SELECTED DRAWING: None
Patent JP-2017099807-A (JP)
Title: Electronic device cover
Inventor: SAKANO MAKOTO
IPC: A45C11/00
Filed: 2015-12-04
Abstract: PROBLEM TO BE SOLVED: To provide an electronic device cover capable of surely holding an electronic device even when unnecessarily spreading a hand holding the cover storing a portable electronic device, requiring no labor for putting a finger insertion part in and out, and having no projection in the cover to be smooth in storing.SOLUTION: A finger insertion part 2 is provided in the reverse side of a lid member of an electronic device cover, and the finger of the hand holding the electronic device cover is inserted into the finger insertion part which projects in folding. With this, even when unnecessarily spreading the hand, the electronic device cover is prevented from sliding down from the hand due to that the finger is inserted into the finger insertion part of the electronic device cover. The finger insertion part is stored by closing the lid member so as to require no labor. Furthermore, since there is no projection on an external surface, the electronic device cover is smoothly stored when storing in a pocket.SELECTED DRAWING: Figure 3
Patent JP-2017104913-A (JP)
Title: Multiple spindle attachment
Inventor: SHIGEMATSU YOSHIHIRO
IPC: F16H7/02
Filed: 2015-12-07
Abstract: PROBLEM TO BE SOLVED: To provide a multiple spindle attachment, easy in changing a plane position of a rotary processing shaft for rotatingly driving a tool, and capable of optionally setting even a position of three or more of tools.SOLUTION: A multiple spindle attachment comprises a support frame 13 fixed to a quill 11 of rotary processing means and having a main spindle 12 on the inside, a first pulley 14 provided on the main spindle 12, a plurality of rotary processing shafts 19-22 provided in the support frame 13, a second pulley 23 provided on the rotary processing shaft 19 by adjusting a height to the first pulley 14, a first belt 27 for connecting the first and second pulleys 14 and 23 via a first tension pulley 26, third pulleys 29-32 arranged by changing a height position from the first and second pulleys 14 and 23 and respectively provided on the rotary processing shafts 19-22 and a second belt 36 for tensioning the third pulleys 29-32.SELECTED DRAWING: Figure 1
Patent JP-2017107660-A (JP)
Title: Battery module integral structure
Inventor: HAYASHISHITA MASATOSHI
IPC: H01M2/10
Filed: 2015-12-07
Abstract: PROBLEM TO BE SOLVED: To suppress a vibration in a battery module integral structure which includes an upper battery module, a lower battery module and an exhaust duct.SOLUTION: The battery module integral structure includes: an upper and a lower battery module which are separately fixed in the vertical direction; an exhaust duct having, on one side face in the lamination direction of each battery module, an upper opening connected to an upper exhaust chamber formed in the upper part of the upper battery module, and a lower opening connected to a lower exhaust chamber formed in the upper part of the lower battery module; an end part cover which fixes the exhaust duct by pressing on the side of each battery module; a surface seal member disposed between each peripheral part of the upper opening and the lower opening of the exhaust duct and an opening end peripheral part of the exhaust chamber; and a resin foam member disposed between the exhaust duct and the end part cover.SELECTED DRAWING: Figure 3
Patent JP-2017107387-A (JP)
Title: Authentication device, authentication device control method, and authentication device control program
Inventor: NAKANO DAISUKE
IPC: G06F21/32
Filed: 2015-12-09
Abstract: PROBLEM TO BE SOLVED: To provide a convenient authentication device, an authentication device control method, and an authentication device control program.SOLUTION: An image forming device 100 is an authentication device for communicating with a wearable terminal 200 which is worn by a user and biometrically authenticates the user. When the wearable terminal 200 comes close to the image forming device 100, the image forming device 100 authenticates the user wearing the wearable terminal 200 on the basis of information received from the wearable terminal 200 (first authentication). After the first authentication, the image forming device 100 authenticates the user operating an operation panel 106 on the basis of a characteristic of a hand or an arm of the user operating the operation panel 106 (second authentication).SELECTED DRAWING: Figure 1
Patent JP-2016113215-A (JP)
Title: Sealable packaging device and related method
Inventor: SEBASTIEN FILY
IPC: A61J1/00
Filed: 2015-12-10
Abstract: PROBLEM TO BE SOLVED: To provide a packaging device comprising a tube which receives a product therein and is sealable by a foam plug.SOLUTION: The packaging device 10 includes an expandable and collapsible tube 12 for receiving a product therein. The tube has a sidewall, a closed end, and an open end. A closed-cell foam plug 14 is compressible and insertable in the compressed state at least partially into the open end of the tube. Upon expanding, the foam plug closes and seals the open end of the tube.SELECTED DRAWING: Figure 1D
Patent JP-2017105398-A (JP)
Title: Brake control device of vehicle
Inventor: USHIROZAKO SHINJI
IPC: B60T8/176
Filed: 2015-12-11
Abstract: PROBLEM TO BE SOLVED: To provide a brake control device of a vehicle which can start ABS control with respect to a front wheel of the vehicle while sufficiently increasing deceleration of the vehicle.SOLUTION: When front wheel deceleration DVWF reaches holding determination deceleration DVWTH (a step S15:YES), holding control for holding brake force is started (a step S16). When first front wheel deceleration DVWF1, front wheel deceleration DVWF at the start time of the holding control is compared with second front wheel deceleration DVWF2, the front wheel deceleration DVWF at the time when predetermined time has elapsed since the first front wheel deceleration DVWF1 is acquired, and then the second front wheel deceleration DVWF2 is below the first front wheel deceleration DVWF1 (a step S23:NO), execution of the holding control is finished so that brake force to be imparted to the front wheel is allowed to increase. When the second front wheel deceleration DVWF2 is larger than the first front wheel deceleration DVWF1 (a step S23:YES), ABS control is started (a step S24).SELECTED DRAWING: Figure 4
Patent JP-2017094024-A (JP)
Title: Extruding device of tablet and package
Inventor: YOSHIMURA KIYOMI
IPC: A61J7/00
Filed: 2015-11-27
Abstract: PROBLEM TO BE SOLVED: To solve the problem in which it is difficult to remove a tablet from a raised part of a PTP package if fingers are weak.SOLUTION: An extruding device of a tablet and package comprises: a substrate body having a through hole on a top face, through which tablets having difference sizes can pass; a pressing fixed board forming a raised part clamping part which is provided on the substrate body, can open and close right and left according to the size and shape of a raised part of a PTP package when a sheet part of an arbitrary PTP package is inserted between the substrate body from the tip, and has means for clamping the raised part; a pushing tool attached to the substrate body through a rotating mechanism and having an extruding piece for dropping a tablet in the PTP package clamped by the raised part clamping part; and a pressing member for pressing the raised part clamping part downward when the extruding piece provided below the pushing tool is lowered.SELECTED DRAWING: Figure 1
Patent JP-2017109293-A (JP)
Title: Vessel bottom coating film peeling method
Inventor: SAKURAI SHIGERU
IPC: B24C11/00
Filed: 2015-12-18
Abstract: PROBLEM TO BE SOLVED: To provide a vessel bottom coating film peeling method capable of reducing all a working environment load, an environment load after work, and a device maintenance load.SOLUTION: This vessel bottom coating film peeling method in an FRP vessel sprays a blas material including sodium bicarbonate particles. The water-insoluble content of the blast material is preferably set to 0.1% or lower by mass. The average diameter of the sodium bicarbonate particles is preferably set to 0.1 to 1 mm. The spraying speed of the blast material is preferably set to 10 to 200 m/s. Water is preferably sprayed together with the blast material.SELECTED DRAWING: None
Patent JP-2017114223-A (JP)
Title: Autonomous unmanned diving machine
Inventor: SAKAGAMI HIROSHI
IPC: B63B22/06
Filed: 2015-12-22
Abstract: PROBLEM TO BE SOLVED: To provide an autonomous unmanned diving machine which enables hoist operation of the autonomous unmanned diving machine to be easily conducted.SOLUTION: An autonomous unmanned diving machine includes: a diving machine body into which a power source is incorporated; a buoy connected with the diving machine body through a rope; and an ejection device which ejects the buoy from the diving machine body in an obliquely upward direction by a compression gas in a state where the diving machine body floats on a sea surface.SELECTED DRAWING: Figure 1
Patent JP-2017118428-A (JP)
Title: Method for cleaning solid-state imaging device and radiation detection device
Inventor: MURANO TAKANORI
IPC: G01N23/207
Filed: 2015-12-25
Abstract: PROBLEM TO BE SOLVED: To provide a method for cleaning a solid-state imaging device capable of easily removing contamination of the solid-state imaging device.SOLUTION: The method of cleaning a solid-state imaging device is a method of cleaning a solid-state imaging device 42 to be used by cooling, which includes exhausting gas generated by heating the solid-state imaging device 42 while heating the solid-state imaging device 42.SELECTED DRAWING: Figure 2
Patent JP-2017115228-A (JP)
Title: Steel wire excellent in coiling and manufacturing method therefor
Inventor: MASUDA TOMOKAZU
IPC: C22C38/50
Filed: 2015-12-25
Abstract: PROBLEM TO BE SOLVED: To provide a steel wire excellent in coiling and a manufacturing method therefor.SOLUTION: The steel wire containing C:0.4 to 0.8 mass%, Si:1.0 to 2.5 mass%, Mn:0.2 to 1.0 mass%, P:0.05 mass% or less, S:0.05 mass% or less, Cr:0.6 to 2 mass% and the balance iron with inevitable impurities and having percentage in iron oxide scale on a steel sheet surface satisfying FeO:10 to 60 vol.%, FeO:over 0 vol.% and 15 vol.% or less and the balance:FeOand FeSiO, average thickness of the iron oxide scale of 0.3 to 2.0 μm and average crystal particle diameter of the iron oxide scale of 0.2 μm or less.SELECTED DRAWING: None
Patent JP-2015519219-A (JP)
Title: コーティングされた物品及び化学蒸着方法
IPC: B32B15/082
Filed: 2013-03-26
Abstract: 【課題】コーティング、コーティングされた物品、及びコーティングを施す方法を提供すること。【解決手段】コーティングされた物品及び化学蒸着方法を開示する。上記コーティングされた物品は、化学蒸着により上記コーティングされた物品に適用された官能化層を含む。上記官能化層は、酸化後官能化層、オルガノフルオロ処理層、フルオロシラン処理層、トリメチルシラン処理表面、オルガノフルオロトリアルコキシシラン処理層、オルガノフルオロシリルヒドリド処理層、オルガノフルオロシリル処理層、トリデカフルオロ１，１，２，２−テトラヒドロオクチルシラン処理層、オルガノフルオロアルコール処理層、ペンタフルオロプロパノール処理層、アリルヘプタフルオロイソプロピルエーテル処理層、（ペルフルオロブチル）エチレン処理層、（ペルフルオロオクチル）エチレン処理層、（ペルフルオロアルキル）エチレン処理層、及びそれらの組み合わせからなる群より選択される層である。上記化学蒸着方法は、蒸気官能化層を適用することを含む。【選択図】図２
Patent JP-2015514474-A (JP)
Title: 組織を切断及び凝固するための装置並びに技術
IPC: A61B18/00
Filed: 2013-04-05
Abstract: 様々な形態は、外科用器具の超音波駆動システムに結合されたエンドエフェクタを駆動するための、システム及び方法を目的とする。発生器は、少なくとも１つの電気信号を生成することができる。この少なくとも１つの電気信号を、第１の論理条件のセットに照合して監視することができる。外科用器具の超音波インピーダンスが、閾値インピーダンスを超過する場合に、その少なくとも１つの電気信号の共振周波数を、基準周波数として記憶することができる。第１の論理条件のセットが満たされること、又は、少なくとも１つの電気信号の共振周波数が、基準周波数とは基準偏差閾値だけ異なることの、いずれかの発生時に、発生器の第１の応答をトリガすることができる。
Patent JP-2015512758-A (JP)
Title: 副鼻腔の治療及び灌注のためのバルーン拡張カテーテルシステム
IPC: A61B17/24
Filed: 2013-04-12
Abstract: 副鼻腔開口の治療及び灌注のための医療用装置が記載されている。装置は、副鼻腔開口にアクセスし、かつその副鼻腔開口を拡張及び灌注する片手操作を可能にする。装置は、副鼻腔ガイドカテーテル、ガイド要素、バルーン拡張カテーテル、バルーンカテーテル移動メカニズム及びガイド要素移動メカニズムを備える。副鼻腔開口を治療し、副鼻腔を灌注するための方法も記載されている。
Patent JP-2015515403-A (JP)
Title: スクリーンプリンタ装備の補正方法及びそれを用いた基板検査システム
IPC: B41F15/40
Filed: 2013-04-29
Abstract: 本発明はスクリーンプリンタ装備のステンシルマスクの補正方法に関し、スクリーンプリンタ装備からフィデュシャル情報の入力を受ける段階と、はんだ検査装備の測定を通じて基板に形成されたパッドの位置情報及びはんだの位置情報を抽出する段階と、パッドの位置情報及びはんだの位置情報を用いてフィデュシャル情報を基準としたステンシルマスクのｘ、ｙオフセット値及び回転量をスクリーンプリンタ装備に伝達する段階と、を含む。このように、スクリーンプリンタ装備から伝送されたフィデュシャル情報に基づいてはんだ検査装備でステンシルマスクのｘ、ｙオフセット値及び回転量を推定し、推定値をスクリーンプリンタ装備にフィードバックさせてステンシルマスクの位置補正を遂行することによって、はんだプリンティングの信頼性を向上させることができる。
Patent JP-2015523125-A (JP)
Title: 高周波手術装置
IPC: A61B18/12
Filed: 2013-05-23
Abstract: 本発明は、生物学的組織（５）を処置、特に切開するか、又は凝固させる高周波出力信号（ａ）を生成する、高周波生成器（３）を有する高周波手術装置（１）に関し、高周波生成器（３）は、高周波生成器の出力信号（ａ）が所定の基本周波数（ｆＧｅｎｅｒａｔｏｒ）を有し、変調装置（９，１１）が設けられるように設計され、変調装置は、変調周波数を用いて出力信号（ａ）を変調するために使用され、変調周波数は基本周波数よりも小さい。高周波手術装置は、変調周波数（ｆＧｅｎｅｒａｔｏｒ）が少なくとも１００ｋＨｚであることと、高周波手術装置（１）の特定の適用に適する、変調された出力信号（ａ１，．．．，ａ４）の波高因子（ＣＦ）が生じるように、出力信号（ａ）を変調することができることとを特徴とする。【選択図】図２
Patent JP-2015519518-A (JP)
Title: 排気後処理システムの部品を監視する方法、排気後処理システム、及び排気後処理システムの制御装置
IPC: F01N3/02
Filed: 2012-06-13
Abstract: ディーゼルエンジンの排気後処理システム（ＥＡＴＳ）の部品は、ＡＨＩ噴射事象の間にディーゼル酸化触媒の全体から放出される熱（ＱＤＯＣ）を測定すること、前記ディーゼル酸化触媒及びＤＰＦの全体にＡＨＩ燃料から入る熱（ＱＥＡＴＳ）を測定すること、完全に機能しているＡＨＩノズルで前記ＡＨＩ噴射事象を実行する間にＡＨＩ燃料から入る熱（ＱＡＨＩ）を計算すること、及びＡＨＩを使用していない間に選択触媒還元ガスが供給ガスの組成に感知している状態で、前記選択触媒還元ガスによってＮＯＸからＮ２へのＮＯＸ転換効率を測定することによって監視される。正しく作動していない部品はこのような測定及び計算を用いて特定される。【選択図】図４
Patent JP-2015521626-A (JP)
Title: ロックド核酸モチーフを含むオリゴヌクレオチドベースの阻害剤
IPC: A61K9/16
Filed: 2013-06-21
Abstract: 本発明は、オリゴヌクレオチドに対する化学修飾モチーフに関する。化学修飾されたアンチセンスオリゴヌクレオチドなどの本発明のオリゴヌクレオチドのｉｎ ｖｉｖｏ有効性は増大し得る。化学修飾されたオリゴヌクレオチドは、効力、送達の効率、標的特異性、毒性、および／または安定性の１つまたは複数において利点をもたらす。化学修飾されたオリゴヌクレオチドはロックド核酸（ＬＮＡ）の特定の化学修飾モチーフまたはパターンを有する。オリゴヌクレオチド（例えばアンチセンスオリゴヌクレオチド）は、ｍｉＲＮＡまたはｍＲＮＡなどのＲＮＡを標的とし得る。本明細書では、化学修飾されたオリゴヌクレオチドを含む組成物、および化学修飾されたオリゴヌクレオチドを、心血管障害を含めた種々の障害に対する治療薬として使用する方法も提供される。
Patent JP-2015523569-A (JP)
Title: 前立腺癌の診断および処置におけるマーカーの使用
IPC: G01N33/53
Filed: 2013-06-27
Abstract: 本発明は、ケラチン4、ケラチン7、ケラチン8、ケラチン15、ケラチン18、ケラチン19、チューブリン-ベータ3、フィラミンB、およびLY9のうちの1種以上、ならびにPSAを用いる前立腺癌の診断、モニタリング、および予後診断のための方法を提供する。本発明は、本発明の方法を実施するためのキットを提供する。【選択図】図７
Patent JP-2015522286-A (JP)
Title: 特異的な結合タンパク質または機能性タンパク質の遺伝子転位を利用した同定
IPC: C12N5/10
Filed: 2013-07-18
Abstract: 本明細書で開示の方法は、所望の機能および／または結合表現型に関して、所望の結合特異性および／または機能を有するポリペプチド、例えば抗体およびその断片などの抗原結合分子を発見および最適化するための、類を見ない効率、柔軟性、有用性および早さを提供する新規技術を説明するものである。この新規方法は、転位性の構築物および転位性のベクターにクローニングされた多様なＤＮＡライブラリー、ならびにそれらを宿主細胞に、機能性トランスポサーゼ酵素を一過的に発現させることによって遺伝子導入することに基づいている。これにより、トランスポゾンを基礎とする発現ベクターが、一工程で確実に、脊椎動物の宿主細胞に効率的、かつ安定に導入され、これを次に、発現したタンパク質の所望の機能または結合表現型に関してスクリーニングすることができ、その後、抗体およびその断片などの発現したタンパク質に関連するコード配列を、標準的なクローニング技術やＤＮＡの配列決定によって同定することができる。