baber/WOPTO huggingface dataset:
Patent CA-2254914-A1 (CA)
Title: Methods of terminal sterilization of biological products
Inventor: ALCOCK ROBERT
IPC: A61K38/00
Filed: 1997-05-14
Abstract: The invention relates to methods of sterilizing biologically active products, particularly therapeutic or prophylactic products and the compositions obtained thereby.  The methods include obtaining a dried sample containing an amount of trehalose sufficient to render heat stability to the product and exposing the dried sample to heating conditions at a temperature and for a duration sufficient to substantially inactivate viruses, especially non-lipid encapsulated viruses. The drying methods include both ambient drying conditions and lyophilization. The heating conditions include any known in the art and cover a wide range of temperatures and heating times. The compositions obtained contain stable products and do not contain measurable infectious virus, particularly parvovirus.
Patent CA-2259390-A1 (CA)
Inventor: FINK DAVID J
IPC: C07K14/78
Filed: 1997-06-05
Abstract: An improved method for producing an aqueous solution of soluble collagen is described. The method comprises the steps of: (A) providing an aqueous ground slurry of insoluble collagen containing insoluble collagen at a first concentration and at a pH effective to obtain activity for a proteolytic enzyme added in step (B); (B) adding a proteolytic enzyme to said slurry; (C) reacting said slurry and enzyme at a temperature, T1 and for a time t1 effective for forming a slurry containing at least some soluble collagen; (D) diluting at least a portion of the slurry formed in step (C) with water to form a diluted slurry containing insoluble collagen at a second concentration;  and (E) reacting said diluted slurry obtained in step (D) at a temperature, T2 and for a time t2 effective to produce a solution containing an increased amount of soluble collagen. The improved process of the present invention permits the preparation of soluble collagen utilizing reduced amounts of enzyme and water, and requires less time at low concentration for completion of the reaction.
Patent CA-2262069-A1 (CA)
Inventor: HERRON NORMAN
IPC: C07C27/04
Filed: 1997-09-02
Abstract: An improved process for decomposing alkyl or aromatic hydroperoxides to form a decomposition reaction mixture containing the corresponding alcohol and ketone. The improvement relates to decomposing the hydroperoxide by contacting the hydroperoxide with a catalytic amount of a heterogeneous catalyst of Nb or Hf hydroxide or oxide. The improvement also relates to decomposing a secondary hydroperoxide by contacting the secondary hydroperoxide with a catalytic amount of a heterogeneous catalyst of Zr or Ti hydroxide or oxide. The catalysts may optionally be supported on SiO2, Al2O3, carbon or TiO2.
Patent CA-2264141-A1 (CA)
Inventor: NICKIAS PETER N
IPC: C08F4/6192
Filed: 1997-08-27
Abstract: On a découvert que certains composés phénoliques peuvent être utilisés comme inhibiteurs de radicaux libres pendant la polymérisation sans désactiver les catalyseurs à métaux de transition. L'utilisation de ces composés pendant la polymérisation est particulièrement avantageuse lorsqu'ils sont sensiblement exempts de composés d'inactivation catalytique, tels que les phénols et quinones à substitution moindre. Cette invention se rapporte à un procédé pour inhiber toute détérioration dans un polymère par addition d'un inhibiteur de radicaux libres pendant ou avant la polymérisation avec un catalyseur à métaux de transition. Il n'est pas nécessaire d'inactiver l'inhibiteur de radicaux libres, étant donné que celui-ci a l'avantage de ne pas inhiber l'activité du catalyseur à métaux de transition. Ce procédé est de préférence précédé par une étape de purification de l'inhibiteur de radicaux libres, pour éliminer les composés qui inhibent l'activité catalytique tels que les quinones et les phénols qui n'ont pas un encombrement stériques suffisants pour éviter l'inhibition du catalyseur. Cette invention se rapporte en outre à une composition contenant au moins un monomère d'oléfine, un polymère de ce monomère, un catalyseur à métaux de transition et au moins un inhibiteur de radicaux libres ayant des substituants suffisants pour créer l'encombrement du groupe d'inhibition actif, de sorte qu'il n'entraîne pas d'inhibition indésirable du catalyseur à métaux de transition. Cette invention est particulièrement utile lorsque le monomère en question comprend du propylène, du styrène ou un dérivé de ceux-ci.
Patent CA-2264744-A1 (CA)
Inventor: GERMAN MICHAEL
IPC: A61P31/04
Filed: 1997-09-18
Abstract: Des cellules épithéliales intestinales d'un sujet mammifère sont modifiées génétiquement afin d'incorporer fonctionnellement un gène exprimant une protéine présentant l'effet thérapeutique souhaité. La transformation des cellules intestinales s'effectue par l'administration, de préférence par voie orale, d'une préparation contenant de l'ADN. La voie orale ou toute autre voie gastro-intestinale représente en effet un moyen simple d'administration. La protéine exprimée est sécrétée directement dans le tractus digestif et/ou dans le flux sanguin en vue de l'obtention de niveaux thérapeutiques de la protéine dans le sang, ce qui permet de traiter le patient nécessitant cette protéine. Le système d'administration de l'invention permet d'administrer à court terme comme à long terme des produits géniques thérapeutiques.
Patent CA-2267646-A1 (CA)
Title: Platelet secretory transport protein
Inventor: REED GUY L
IPC: A61K38/00
Filed: 1997-10-07
Abstract: Disclosed is a novel protein designated platelet secretory transport protein (PSTP). PSTP occurs in platelets and binds to syntaxin. An isolated DNA encoding PSTP, vectors and cells containing the DNA, and PSTP specific antibodies are also disclosed. A PSTP antibody can be used to target a compound to an activated platelet in a mammal for diagnostic or therapeutic purposes. Also disclosed is an in vitro screening method for identifying a compound that inhibits PSTP-syntaxin binding, and an in vitro method for identifying a compound that inhibits PSTP gene expression.
Patent CA-2269295-A1 (CA)
Title: Simplified unidirectional twist-up dispensing device with incremental dosing
Inventor: SMITH GENEVIEVE RYLAND
IPC: A46B11/02
Filed: 1997-10-23
Abstract: An unidirectional twist-up dispensing device (10) with incremental dosing for dispensing a product is provided. This twist-up dispensing device includes a hollow housing (20) defining a chamber (21) having an open dispensing end (24) and an open actuating end (26) having an interior surface. A piston (40) located within the chamber being limited to translational movement within the chamber. The piston having a top side (42) facing the dispensing end (24) of the housing forming a variable volume portion of the chamber for storing the product. The piston also having a threaded rod (46) extending therefrom opposite the top side. An actuator (50) having a threaded aperture therethrough that engages the interior surface of the actuating end of the housing is also provided. The threaded aperture is concentric in the actuator and the actuator is adapted to rotate with respect to the housing in only one direction. The threaded rod engages the threaded aperture such that advancement of the piston toward the dispensing end occurs when the actuator is rotated, thereby causing the product to be dispensed. An applicator (80) can be attached to the dispensing end of the housing in fluid communication with the variable volume portion (22) of the chamber wherein the product is dispensed through the applicator. The applicator comprises a ferrule (82) and an application portion (84). The ferrule is attached to the dispensing end of the housing and the application portion has at least one orifice located therein. Several versions of the applicator are illustrated, including a fiber brush and a flocked application surface.
Patent CA-2269634-A1 (CA)
Inventor: BILLING-MEDEL PATRICIA A
IPC: C12Q1/68
Filed: 1997-10-31
Abstract: L'invention concerne un ensemble de séquences d'ARN contiguës et se chevauchant partiellement, ainsi que des polypeptides codés par celles-ci, dénommées BS 106 et transcrites à partir de tissu mammaire. Ces séquences peuvent être utilisées pour le dépistage, le diagnostic, l'évaluation du stade, la surveillance, le pronostic, la prévention ou le traitement concernant des pathologies mammaires telles qu'un cancer du sein, ou bien pour la détermination de la prédisposition d'un individu à une telle pathologie. L'invention concerne également des anticorps qui se fixent spécifiquement au polypeptide ou à la protéine codés par BS 106, ainsi que des agonistes ou des inhibiteurs qui empêchent l'action du polypeptide codé par BS 106 spécifique du tissu concerné, ces molécules pouvant être utilisées pour la thérapie de pathologies, tumeurs ou métastases mammaires.
Patent CA-2271446-A1 (CA)
Title: Circuit arrangement for operating electrical lamps
Inventor: FRANCK FELIX
IPC: H05B39/04
Filed: 1999-05-12
Abstract: The invention relates to a circuit arrangement for operating electrical lamps which encompasses an invertor with oscillation build-up circuit (trigger generator), comprising diac and drive circuit. The drive circuit comprises a high-pass filter, in particular an RC high-pass filter. As a result, the trigger initiation is shifted closer to the zero crossing of the supply voltage. This means, in turn, that a more sinusoidal power supply current consumption with a smaller proportion of harmonics is obtained. In addition, more stable lamp operation is achieved in combination with power supply segment control dimmers.
Patent CA-2272762-A1 (CA)
Title: Distributor device for water conditioner backflush apparatus
Inventor: FIELD GEORGE RAYMOND
IPC: B01J49/00
Filed: 1999-05-20
Abstract: A distributor device for use in a water conditioner including a tank, and an apparatus for backflushing a bed of particulate material in the tank, which includes a tubular casing, a vertical tube in the casing, a cap on the top end of the casing and suitable valves for causing the flow of particulate material upwardly between the casing and tube, and then through a gap between the casing and cap during a backflush operation, the distributor device including a flexible, collapsible, umbrella-shaped body which is mounted on the casing immediately below the cap, and springs for biasing the body to the open position. Inlet tubes extend outwardly from the bottom of the casing approximately the same distance as the distributor for ensuring even distribution of liquid at the bottom of the bed.
Patent CA-2273634-A1 (CA)
Title: Method and apparatus for the collection of cookies and other information
Inventor: BLUMENAU TREVOR
IPC: G06Q30/02
Filed: 1999-06-02
Abstract: A method and system for collecting access information relating to a plurality of web sites. The method may include receiving a first request from a user device, generating a user identifier, and sending the user identifier, the identity of at least two web sites, and an instruction to the user device to cause the user device to send the user identifier to the at least two web sites.
Patent CA-2276287-A1 (CA)
Inventor: TRIER KLAUS
IPC: A61K31/433
Filed: 1998-01-05
Abstract: The invention relates to a method for identification of substances which are applicable for treatment or prevention of an insufficient longitudinal growth of the eye (hypermetropia) or for treatment or prevention of an excessive longitudinal growth of the eye (myopia);  substances identified by the method for treating or preventing conditions related to the longitudinal growth of the eye; substances and mixtures of substances for the preparation of a pharmaceutical composition for the treatment or prevention of abnormal growth of the axial length of the eye. The identification involves measuring the effect of the substances on the retinal pigment epithelium of the eye, e.g. by detecting the metabolic effect of the substance on the retinal epithelium, the effect on the standing potential or the effect on the proteoglycanes of the scleral tissue of the eye, by way of EOG examination, by way on the size of the so-called c-wave in ERG-recordings, or by the state of the Ca2+-channels or on the [3H]-ryanodine receptors of the retinal pigment epithelium.
Patent CA-2276957-A1 (CA)
Title: Drawer slide and drawer incorporating quick-release connection
Inventor: WHITTLESEA JOHN HENRY
IPC: A47B88/04
Filed: 1999-07-06
Abstract: A drawer slide and drawer slide combination which incorporates a connecting clip for providing a quick-release connection between the drawer slide 3 and the drawer 21 the clip comprising a fixing part 1 for connection preferably with a snap-fit, and preferably to the slide and a latching part 13 having a projection 17 thereon, preferably for engagement with an aperture 19 in the drawer 21. The latching part 13 is preferably spring loaded and preferably pivotable between a first aperture engaging position for connecting the drawer to the slide and a second release position in which the projection 17 no longer engages in the aperture in the drawer, whereby the drawer and slide can be disconnected. Disconnection is achieved by applying finger pressure to a release latch portion 15, which may be integral with the latching part 13. The connecting clip could be made of spring metal, but is preferably made of resiliently deformable plastics material. It may be formed in one or in two parts.
Patent CA-2278506-A1 (CA)
Inventor: FEUSTEL DIETER
IPC: C11D1/00
Filed: 1998-02-02
Abstract: L'invention concerne une composition de tensioactifs contenant environ 20 % en poids à environ 76 % en poids d'éthoxylate d'alcool gras présentant un degré d'éthoxylation d'au moins 14, environ 4 % en poids à environ 40 % en poids d'alkylpolyglycoside, et environ 20 % en poids à environ 60 % en poids d'eau. Cette composition est liquide à température ambiante, exempte de gel ou de phase solide. L'invention concerne également des latex contenant ladite composition de tensioactifs et un procédé pour produire lesdits latex.
Patent CA-2278730-A1 (CA)
Inventor: DUPREE WAYNE P
IPC: G06F9/46
Filed: 1998-02-02
Abstract: A dedicated context-cycling microprocessor which features a plurality of input/output circuits for receiving and transmitting information and an individual set of dedicated on-board resources for each plurality of processing contexts. A distinct processing context is provided for each of a plurality of the input/output circuits, and a timed context is also provided for concurrently scheduling multiple processing contexts and enforcing time constraints associated with this schedule. The timed context has a pseudo-queue list which represents an ordered set of data parameters and program memory addresses for scheduling each of the processing contexts. The dedicated on-board resources include a plurality of registers for each of the processing contexts, such as at least one general purpose register and a program counter.  A multiplexer circuit is also provided for moving data between the input/output circuits, the dedicated registers of the processing contexts and the computational unit. The input/output circuits include at least one serial and shared memory management unit, a plurality of embedded SCSI interfaces and a plurality of memory mapped registers. The dedicated context cycling microprocessor is also adapted to work in conjunction with, and effectively control another microprocessor, as well as control the access to an external memory system which is shared between these two microprocessors.
Patent CA-2279214-A1 (CA)
Title: Antiviral agents
Inventor: YUASA SATOSHI
IPC: A61K31/52
Filed: 1998-01-29
Abstract: Antiviral agents containing as the active ingredients at least two substances selected from the group consisting of 6-benzyl-1-ethoxymethyl-5-substituted uracil derivatives such as 6-benzyl-1-ethoxymethyl-5-isopropyluracil and nucleoside-base reverse transcriptase inhibitors such as 3'-azido-3'-deoxythymidine and 2'-deoxy-3'-thiacytidine and esters thereof and exerting synergistic antiviral effects on retroviruses, etc.
Patent CA-2279238-A1 (CA)
Title: Method for producing high-temperature resistant technical paper and paper produced according to said method
Inventor: BECKER UWE
IPC: D21H13/38
Filed: 1998-02-28
Abstract: The invention relates to a method for producing high-temperature resistant technical paper, wherein fibers are mixed with wet paper pulp and technical paper is subsequently produced by dehydrating said pulp, thereby causing the paper material to be compressed. According to said method, cut fibers and previously thermally pre-shrunk fibers are added to the wet pulp so that the finished technical paper undergoes low thermal shrinkage of less than 1 % when used at high temperatures.
Patent CA-2280324-A1 (CA)
Inventor: CHENG TERRY SI-FONG
IPC: H04B7/005
Filed: 1999-08-16
Abstract: A code-division multiple access power control for paging channel power and initial tragic channel power dynamically determines optimum initial channel power in accordance with pilot signal strength of a pilot signal as received at a mobile station and current forward link loading of the desired sector. The optimum initial paging channel power and initial traffic channel power may be determined either at a base station or a mobile switching center of the mobile communication system.  A paging signal or call is transmitted from the base station to the mobile station over a paging channel and a traffic channel at the optimum paging channel and initial traffic channel power.
Patent CA-2280965-A1 (CA)
Title: Input/output device and input/output method, and receiver
Inventor: HAMADA ICHIRO
IPC: H04N21/4408
Filed: 1998-12-15
Abstract: A switching portion of an IRD supplies a non--descrambled TS (transport stream) received from a front end portion or a descrambled TS received from a descrambler to a DVCR connected to an IEEE 1394 interface. In addition, data received from the DVCR is supplied to the descrambler.
Patent CA-2284578-A1 (CA)
Title: A camisole garment
Inventor: RIBBLE BRENDON FRANK
IPC: A41D7/00
Filed: 1998-04-06
Abstract: A camisole garment (2) including an elastic system which is under tension and a ruffle which forms an edge (4) of the elastic structure whereby the curl-over of the structure is minimized during use. In addition, a continuous process for the manufacture of garments including sleeveless tops, shirts, or blouses.
Patent CA-2285429-A1 (CA)
Title: Absorbent article having improved comfort during use by improved fit even when loaded and improved rewet performance
Inventor: YOUNG GERALD ALFRED
IPC: A61F13/49
Filed: 1997-03-27
Abstract: Absorbent article comprising an absorbent core with a crotch region and at least one waist region, whereby said crotch region has a lower ultimate fluid storage capability than said at least one waist region. The article further has an improved fluid handling performance in particular a low rewet value for minimising skin hydration during use, such as measured by the post acquisition collagen rewet method value not exceeding 180 mg.
Patent CA-2287443-A1 (CA)
Inventor: OTTESEN HAL HJALMAR
IPC: G11B5/596
Filed: 1999-10-26
Abstract: A method and apparatus for identifying and filtering a resonance frequency of a support structure supporting a read/write head in proximity with a data storage medium involves obtaining a particular sample of a position error signal (PES) frequency transform, preferably using Goertzel's algorithm. The velocity of the data storage medium is varied, and the magnitude of a particular PES frequency transform sample is computed at each of the velocities. A resonance frequency of the support structure is calculated using the velocity associated with the particular sample having a maximum magnitude. The effects of one or more resonance frequencies associated with a read/write head suspension may be canceled in a position error signal using one or more programmable filters provided in each servo loop. A processor programs the filters using the calculated resonance frequencies and adjusts to compensate for the additional lag introduced into the respective servo loops by the selected programmable filters. A method and apparatus for identifying one or more resonance frequencies of one or more read/write head support structures according to the principles of the present invention may be implemented in a data storage system and, preferably, implemented in-situ a data storage system without resort to circuitry external to the data storage system.
Patent CA-2287502-A1 (CA)
Inventor: SOSHIRODA TETSUO
IPC: C22C38/54
Filed: 1999-03-12
Abstract: A high strength hot rolled steel sheet having good strength-elongation balance and stretch-flangability and being excellent in formability, wherein the composition of the steel satisfies the following requirements (by mass %): C is 0.05 to 0.15 %, Si is 0.5 to 2.0 %, Mn is 0.5 to 2.0 %, P is 0.05 % or less, S is 0.010 % or less, Al is 0.005 or more and less than 0.10 %, and Fe and obligatory impurities account for the residue of steel, wherein metal systems present are mainly three phases of ferrite, retained austenite and bainite, the amount of ferrite ¢V(F)! being 60 to 95 % by area, the amount of retained austenite ¢V(.gamma.)! being 3 to 15 % by volume, and the amount of ferrite ¢V(B)! being 1.5 times that of retained austenite ¢V(.gamma.)! by area or more, and wherein an average hardness of bainite is 240 to 400 Hv.
Patent CA-2289018-A1 (CA)
Title: Cooling control device of internal combustion engine
Inventor: TAKAHASHI MASANORI
IPC: G06Q50/20
Filed: 1999-04-06
Abstract: A cooling control device capable of preventing such a problem that an internal combustion engine is overheated and ensuring the display of its fail-safe function, wherein a coil-shaped spring member (45) is wound on a valve stem (27) of a butterfly valve (26) for regulating the flow rate of cooling water, both ends of the spring member are engaged with pin members (27a, 27b) installed in the valve stem (27), the pin member (27a) is formed of a material fused when the temperature rises beyond a specified limit and the pin member (27a) is fused when the cooling water temperature is raised to a specified limit, thus one end part (45a) of the spring member (45) is brought in contact with an engaging pin (25a) projecting toward the valve stem (27) by a return force of the spring member so as to rotate the valve stem (27) in the opening direction of the butterfly valve (26) by a reaction, whereby the cooling water can be circulated sufficiently so as to prevent such a problem that an engine is overheated.
Patent CA-2289231-A1 (CA)
Title: A subscriber unit and method for use in a wireless communication system
Inventor: ODENWALDER JOSEPH P
IPC: H04B1/707
Filed: 1998-05-13
Abstract: A set of individually gain adjusted subscriber channels (402, 404, 411, 415) are formed via the use of a set of orthogonal subchannel codes (Wc, Ws, Wf) having a small number of PN spreading chips per orthogonal waveform period. Data to be transmitted via one of the transmit channels is low code rate error correction encoded and sequence repeated before being modulated with one of the subchannel codes, gain adjusted, and summed with data modulated using the other subchannel codes. The resulting summed data (410, 420) is modulated using a user long code and a pseudorandom spreading code (PN code) and upconverted for transmission. The use of the short orthogonal codes provides interference suppression while still allowing extensive error correction coding and repetition for time diversity to overcome the Raleigh fading commonly experienced in terrestrial wireless systems. The set of sub-channel codes may comprise four Walsh codes, each orthogonal to the remaining codes of the set. The use of four sub-channels is preferred as it allows shorter orthogonal codes to be used, however, the use of a greater number of channels and therefore longer codes is acceptable. Preferably, pilot data is transmitted via a first one of the transmit channels and power control data transmitted via a second transmit channel. The length, or number of chips, in each channel code may be different to further reduce the peak-to-average transmit power for higher rate data transmission.