baber/WOPTO huggingface dataset:
Patent AU-2017219834-B2 (AU)
Title: BYL719 (Alpelisib) for use in the treatment of PIK3CA-Related Overgrowth Spectrum (PROS - CLOVES syndrome)
Inventor: CANAUD GUILLAUME
IPC: A61P43/00
Filed: 2017-02-17
Granted: 2022-06-30
Abstract: - 20 - ABSTRACT OF THE INVENTION METHODS FOR THE TREATMENT OF PIK3CA-RELATED 5 OVERGROWTH SPECTRUM The present invention relates to a method of treating PIK3CA-Related Overgrowth Spectrum (PROS) more particularly, Congenital, Lipomatous, Overgrowth, Vascular Malformations, Epidermal Nevi and Spinal/Skeletal Anomalies and/or Scoliosis (CLOVES) 10 syndrome. To date, there are no specific treatments for patients and no animal models of PROS to better understand the physiopathology of the disorder. Inventors developed a genetic mouse model of PROS that recapitulates the human disease and demonstrated the efficacy of BYL719. Based on these results they treated two patients, one adult and one child, with severe CLOVES syndrome using BYL719. The drug had a robust efficiency on disease in the 15 two patients inducing quick recovery of all affected organs. Thus, the invention relates to a method of treating PROS in a subject in need thereof comprising the step of administrating the subject with a therapeutically effective amount of BYL719.
Patent AU-2017226825-B2 (AU)
Title: A ball launcher and a ball gaming system including such ball launcher
Inventor: BURGSTALLER JÜRGEN
IPC: A63F5/00
Filed: 2017-03-03
Granted: 2021-10-14
Abstract: The present invention relates to a roulette wheel apparatus, and in particular to a ball launcher for use in a gaming system such as a roulette wheel apparatus and roulette wheel apparatus comprising the ball launcher. The airflow generator for generating the airstream through the launch tube is controlled by an airflow controller adapted to reverse airflow direction and/or to cause airflow in a direction opposite to the ball moving direction when a detected ball speed is higher than a desired ball speed and/or the ball speed is to be decreased.
Patent AU-2017232123-B2 (AU)
Title: Method and system for applying electric fields to multiple solar panels
Inventor: MCNAMARA ROBERT P
IPC: H02J3/38
Filed: 2017-09-21
Granted: 2019-10-10
Abstract: A solar cell management system for increasing the efficiency and power output of a solar cell and methods for making and using the same. The management system provides an electric field across one or more solar cells. The imposed electric field exerts a force on both the electrons and holes created by light incident on the solar cell and accelerates the electron-hole pairs towards the electrodes of the solar cell. The solar cell management system considers variations in configuration of solar cells to maximize the power output of the solar cells. The accelerated electron-hole pairs have a lower likelihood of recombining within the cells' semiconductor's material. This reduction in the electron-hole recombination rate results in an overall increase in the solar cells' efficiency and greater power output.
Patent AU-2017236013-B2 (AU)
Title: Uv-protective compositions and their use
Inventor: LANDA BENZION
IPC: C08K3/22
Filed: 2017-09-29
Granted: 2019-07-11
Abstract: Disclosed are compositions comprising inorganic UV-absorbing agents and the use of such compositions, in particular for protecting a subject or the surface of an inanimate object against a harmful effect of ultraviolet radiation.
Patent AU-2017237090-B2 (AU)
Title: Ophthalmic apparatus with corrective meridians having extended tolerance band by modifying refractive powers in uniform meridian distribution
Inventor: ZHAO HUAWEI
IPC: A61F2/16
Filed: 2017-03-23
Granted: 2021-10-21
Abstract: The embodiments disclosed herein include improved toric lenses and other ophthalmic apparatuses (including, for example, contact lens, intraocular lenses (IOLs), and the like) and associated method for their design and use. The apparatus includes one or more optical zones, including an optical zone defined by a polynomial-based surface coincident at a plurality of meridians having distinct cylinder powers, wherein light incident to a given region of each of the plurality of meridians, and respective regions nearby, is directed to a given point of focus such that the regions nearby to the given region direct light to the given point of focus when the given meridian is rotationally offset from the given region, thereby establishing an extended band of operation, and wherein each of the plurality of meridians is uniformly arranged on the optical zone for a same given added power (in diopters) up to 1.0D (diopters).
Patent AU-2017252163-B2 (AU)
Title: Dynamically convey information of demodulation reference signal and phase noise compensation reference signal
Inventor: ISLAM MUHAMMAD NAZMUL
IPC: H04W72/04
Filed: 2017-03-21
Granted: 2021-06-24
Abstract: DM-RS symbols may be inserted in the beginning of a subframe, or in two parts of the subframe. In one aspect, a method, a computer-readable medium, and an apparatus for dynamically conveying DM-RS information are provided. The apparatus may be a base station. The apparatus may determine the number of DM-RS symbols and/or the locations within a subframe for transmission of the DM-RS symbols. The apparatus may transmit the number of the DM-RS symbols and/or the locations within the subframe for transmission of the DM-RS symbols to a UE. In another aspect, a UE may receive the number of DM-RS symbols and/or the locations within a subframe for transmission of the DM-RS symbols from a base station. The UE may decode the DM-RS symbols from the subframe based on the number of the DM-RS symbols and/or the locations within a subframe for transmission of the DM-RS symbols.
Patent AU-2017281589-B2 (AU)
Title: Microbial carotenoids affecting gut microbial composition
Inventor: POSSEMIERS SAM
IPC: A61K35/74
Filed: 2017-06-22
Granted: 2023-03-23
Abstract: The present invention relates to the use of carotenoids, in particular a microbial carotenoid compound of formula I, such as methyl-glycosyl-apo-8'-lycopenoate or glycosyl-apo-8'-lycopene, for restoring and/or maintaining a health-beneficial gut microbial composition in a subject. The invention further provides the use of said compound in the treatment of disorders associated with a disturbed intestinal barrier integrity, such as for example irritable bowel syndrome. Further, a compound or composition comprising a microbial carotenoid compound is disclosed for use in the prevention and/or treatment of disorders associated with disturbed intestinal barrier integrity.
Patent AU-2017318623-B2 (AU)
Title: A remotely activated vehicle anti-theft device
Inventor: TALJAARD PHILIPPUS PETRUS ERASMUS
IPC: B60R25/04
Filed: 2017-06-13
Granted: 2022-05-19
Abstract: A remotely activated vehicle anti-theft device 10 and system 50 for preventing vehicle theft is provided. The device 10 is moved between unlocked, locked and priority locked states using either a wireless vehicle remote 51 or a mobile phone 52. The mobile phone 52 enjoys priority over the remote control 51 and overrides it when the device is in its priority locked state. It includes a pivotal locking member 17 which is movable between an open position (unlocked state) in which the member is spaced away from a gear 12, permitting it to rotate freely, and a locked position (locked and priority locked states), in which the member 17 engages the gear 12 and prevents rotation thereof, thereby immobilising a vehicle. The device 10 includes an ECU 22, wireless communication module 34, actuator 23, GPS 6 and speed sensor 7 housed in a tamper-proof casing 27.
Patent AU-2017335648-B2 (AU)
Title: Method for treating cancer using a combination of DNA-damaging agents and DNA-PK inhibitors
Inventor: BOUCHER DIANE M
IPC: A61K31/506
Filed: 2017-09-27
Granted: 2022-02-17
Abstract: Described herein are methods of treating a proliferative disease in a subject by administering a DNA-damaging agent and between about 8 and about 48 hours later administering to the subject a DNA-PK inhibitor. Exemplary DNA-PK inhibitors are represented by Formula (B-I): and by pharmaceutically acceptable salts thereof, wherein R
Patent AU-2017376822-B2 (AU)
Title: Radiolabelled material for targeted administration
Inventor: STEPHENS ROSS WENTWORTH
IPC: A61K51/06
Filed: 2017-12-15
Granted: 2023-08-03
Abstract: The invention relates to a radiolabelled material comprising a polymer, a radioactive isotope, and an immobilizing agent, wherein the immobilizing agent is capable of immobilizing the radioactive isotope on or in the polymer, and wherein the immobilizing agent is a macromolecule comprising a polycation with multiple pendant metal-chelating side-chains. The invention also relates to a process for making a radiolabelled material, to use of a radiolabelled material for the preparation of medicaments for treating cancer and/or for radiation imaging and to use of a radiolabelled material in the treatment of cancer. There is further described use of an immobilizing agent to immobilize a radioactive isotope on or in a polymer.
Patent AU-2017396541-B2 (AU)
Title: Reliability evaluation method for hoist main shaft of kilometer-deep mine considering multiple failure modes
Inventor: LU HAO
IPC: B66B5/00
Filed: 2017-09-18
Granted: 2019-05-23
Abstract: The present invention discloses a reliability evaluation method for a hoist main shaft of a kilometer-deep mine considering multiple failure modes. First, a parametrical three-dimensional model of the main shaft is established according to physical dimensions of the main shaft. Then, a sampling matrix for random variables of the 10 main shaft is established according to probability types of the random variables, and strength and stiffness responses of the main shaft are solved using the sampling matrix with a finite element method. Afterwards, an explicit function defining a relationship between the responses and the matrix for the random variables is established using a neural network approach, and explicit performance functions in a strength failure 15 mode and in a stiffness failure mode are separately established according to strength and stiffness design criteria; and then, probabilities of these two failures are calculated by means of a saddlepoint approximation method. Finally, a joint failure probability model combining the two failure modes is established using a Clayton copula function, and system reliability in the case of a joint failure is solved using a bound reliability 20 method. The present invention considers probability correlation between a strength failure and a stiffness failure, and can more accurately and reasonably evaluate system reliability of the hoist main shaft.
Patent AU-2017417515-B2 (AU)
Title: Device for closing an inspection opening, and method for inserting a device of said type
Inventor: GÜNTHER MICHAEL
IPC: E04F19/08
Filed: 2017-06-08
Granted: 2021-07-01
Abstract: The invention relates to a device for closing an inspection opening, and to a method for inserting such a device for closing an inspection opening into a board-like or panel-like structure element of a dry building structure, in which the stated device comprises a frame framing the inspection opening and a closure cover for closing the inspection opening. With regard to a method according to the invention, for the frame, a board-like or panel-like material is provided which preferably substantially corresponds to the material of the board-like or panel-like structure element, in that the closure cover and, if provided and/or necessary, possibly at least one further device element can be adapted and/or fitted to and/or into the frame already at the factory.
Patent AU-2017430010-B2 (AU)
Title: Sewing machine needle clamp device
Inventor: SAKUMA TOHRU
IPC: D05B55/02
Filed: 2017-08-29
Granted: 2023-02-02
Abstract: [Problem] To easily and reliably attach or secure a sewing machine needle to a needle clamp or replace the sewing machine needle. [Solution] A needle clamp (5) that clamps a sewing machine needle (3) includes: a clamp lever (19) which has a housing recess (7) that houses a sewing machine needle shank (15) and a clamp arm (21) that engages with the needle shank, and which is secured to a clamp lever shaft (17) that loosely fits in a long hole (13b) bored through the needle clamp in a manner that is openably closable relative to the housing recess; and a needle clamp spring (23) that causes the clamp lever to spring out beyond a straight line that connects a center point (N) of the needle shank to a center point of the clamp lever shaft. The needle clamp has a cam (71) and the clamp arm has a cam follower (70) that engages with the cam. As a path of movement for the clamp lever shaft, which constitutes the center of rotation (P) of the clamp lever, the long hole has three surfaces along which the cam follower moves over the cam.
Patent AU-2018214013-B2 (AU)
Title: Cochlear implant fitting via efferent nerve fibers
Inventor: SCHWARZ KONRAD EUGEN
IPC: A61N1/36
Filed: 2018-08-07
Granted: 2020-04-09
Abstract: A method of fitting a cochlear implant in an ipsilateral ear of a subject where the cochlear implant having an electrode array with one or more electrode contacts. The method comprises applying broad-band white noise stimulus to a contralateral ear in order to mask efferent nerve fibers, applying a single pulse stimulus to the ipsilateral ear and then measuring base-line evoked compound action potential (CAP) signals in the ipsilateral ear for an electrode contact during a refractory period, applying a sequence of separated single pulse stimuli to the contralateral ear and then measuring attenuated CAP signals in the ipsilateral ear for the electrode contact during the refractory period, comparing the measured attenuated CAP signals to the measured base-line CAP signals in order to determine a CAP threshold for the electrode contact, and adjusting processing parameters of the cochlear implant based on the CAP threshold.
Patent AU-2018228275-B2 (AU)
Title: Composite support pole
Inventor: RUSSO MARK ANTHONY
IPC: B25G1/04
Filed: 2018-03-01
Granted: 2022-10-20
Abstract: A composite support pole for supporting an overhead load at a free end thereof and including at least one composite support member. The support member includes a tensile wall for, in use, bearing tensile load, the tensile wall formed as a cylindrical segment having a circular arc which defines a tensile wall arc length. The support member also includes a compressive wall which opposes the tensile wall, for, in use, bearing compressive load, the compressive wall formed as a cylindrical segment having a circular arc which defines a compressive wall arc length that is greater than the tensile wall arc length. The support member further includes a pair of opposing side walls extending between the tensile and compressive walls, the side walls being planar or having a curvature that is less than that the curvature of the tensile and compressive walls.
Patent AU-2018291496-B2 (AU)
Title: Novel CRISPR RNA targeting enzymes and systems and uses thereof
Inventor: CHENG DAVID R
IPC: C12N15/113
Filed: 2018-07-02
Granted: 2019-12-19
Abstract: The disclosure describes novel systems, methods, and compositions for the manipulation of nucleic acids in a targeted fashion. The disclosure describes non-naturally occurring, engineered CRISPR systems, components, and methods for targeted modification of a nucleic acid.
Patent AU-2018295788-B2 (AU)
Title: Micro-optic device projecting multi channel projected imagery
Inventor: JOLIC KARLO IVAN
IPC: B42D25/30
Filed: 2018-07-03
Granted: 2023-08-10
Abstract: A micro-optic device, including: a substrate; a plurality of image elements in an image plane; and a plurality of focusing elements, each focusing element focusing light to a focal point on the image plane and magnifying any portion of an image element falling within the focal point to thereby produce an image pixel projected to a user at one or more viewing angles, the focal point having an extent smaller than the image element, wherein each image element includes an image sub-element having a different discernible level of brightness to elsewhere in the image element, the brightness of each projected image pixel being dependent on the proportion of the focal point filled with the image sub-element, and wherein each image sub-element has one or more attributes in the image plane, such that, from a given viewing angle, the brightness of each projected image pixel is dependent on each attribute of each image sub-element.
Patent AU-2018322505-B2 (AU)
Title: Process for preparing an intermediate for avibactam
Inventor: QI YUXIN
IPC: C07B57/00
Filed: 2018-03-06
Granted: 2020-04-30
Abstract: The present invention discloses a method for preparing an intermediate for avibactam, and specifically relates to a method for preparing ({[(2S,5R)-2-carbamoyl-7-oxo-1,6-diazabicyclo[3.2.1]oct-6-yl]oxy}sulfonyl)tetrabutylammo nium salt (II). With 5R- [(benzyloxy) amino] piperidine-2S- carboxylate oxalate (III) as the raw material is reacted with the amide of Formula IV via amidation to prepare the compound of Formula V; the resulting compound of Formula V is reacted with the carbonylation reagent via urea cyclization to obtain the compound of Formula VI; the benzyl or the substituted benzyl in the compound of Formula VI is removed by catalytic hydrogeneration, then the resulting compound is sulfatated by sulfur trioxide complex and is salinized into tetrabutylammonium to obtain the final product (II). The reaction condition for the process of the present application is easily operable; the preparing process has a strong operability, a simple process, a low cost, less byproducts, and a high reaction atomic economy; the obtained product (II) has a high purity and a high yield.
Patent AU-2018328693-B2 (AU)
Title: Free fall winch
Inventor: HAUSLADEN NORBERT
IPC: B66D5/18
Filed: 2018-08-27
Granted: 2023-12-14
Abstract: The invention relates to a free fall winch comprising a drum, which can be rotationally driven by a winch drive, wherein a free fall brake is provided for braking the drum in free fall operation. According to the invention, a torque acting on the free fall winch, which depends on the free fall braking torque, is detected by means of a detection device, and a brake actuation force with which the free fall brake is actuated is controlled or adjusted by a control device according to the detected torque.
Patent AU-2018339943-B2 (AU)
Title: Housing assembly for terminal and terminal with housing assembly
Inventor: SHE BINBIN
IPC: H05K5/02
Filed: 2018-08-20
Granted: 2020-11-26
Abstract: The present disclosure provides a housing assembly for a terminal, and a terminal with the housing assembly. The housing assembly may include a middle frame, an electroacoustic assembly and a decorative member. The electroacoustic assembly is arranged on the middle frame and defines a sound transmission hole. The decorative member defines an inner space. The at least portion of the decorative member faces the sound transmission hole. The decorative member is fixed to the electroacoustic assembly. The sound transmission hole directly communicates with the inner space of the decorative member.
Patent AU-2018348287-B2 (AU)
Title: Screening system with vibration-node-arranged vibration systems
Inventor: LEUSCHEN GUIDO
IPC: B06B1/16
Filed: 2018-10-08
Granted: 2021-12-09
Abstract: The invention relates to a screening system (1) for screening material to be screened, in particular for screening mineral stone, the system comprising: a screen box (2) which comprises two outer side walls (31, 32), wherein at least two vibration systems (4) are arranged on each of the two side walls (31, 32) for exciting vibration and the two side walls (31, 32) each have at least two vibration nodes (S) in accordance with a bending mode; at least two crossmembers (5), which connect the two side walls (31, 32) to one another; and at least one screen deck (6), which is supported on the at least two crossmembers (5), the two vibration systems (4) on each of the side walls (31, 32) being arranged in such a way that each vibration system (4) is arranged in the region of a vibration node (S) of the side wall (31, 32) in question. The invention also relates to a method for screening material to be screened, in particular for screening mineral stone, by means of a screening system of the aforementioned type.
Patent AU-2018352104-B2 (AU)
Title: Compositions exhibiting synergy in biofilm control
Inventor: CHAPMAN JOHN S
IPC: A01N25/30
Filed: 2018-10-12
Granted: 2023-12-21
Abstract: A method of controlling and removing biofilm on a surface in contact with an aqueous industrial system comprising the step of adding an effective amount of biofilm-disrupting agent and adding a biocide to the aqueous system being treated to reduce and remove biofilm forming microbes from a surface in contact with the aqueous system is disclosed. Also disclosed is a synergistic composition of polyethyleneimine and an oxidizing biocide.
Patent AU-2018395919-B2 (AU)
Title: Efficiently propagating diff values
Inventor: JAYAKAR SANJAY
IPC: G06F16/178
Filed: 2018-12-13
Granted: 2021-08-05
Abstract: The disclosed technology relates to a system configured to identify at least one difference between a sync tree and at least one of a remote tree and a local tree. The sync tree represents a known synced state between a server state and a file system state, the remote tree represents the server state, and the local tree represents the file system state. The system may further generate, based on the at least one difference, a set of operations configured to converge the server state and the file system state and manage the execution of the set of operations. The state of a node in a tree is represented by a value based on the hash values of its descendants. When a node is added or removed, the value of the ancestor is recalculated based on its old value and the hash value of the added or removed node.
Patent AU-2019203480-B2 (AU)
Title: Delamination container
Inventor: TARUNO SHINSUKE
IPC: B65D1/02
Filed: 2019-05-17
Granted: 2020-12-24
Abstract: A delaminatable container excellent in productivity is provided. According to the 
first aspect of the present invention, a delaminatable container, comprising: a 
container body having an outer shell and an inner bag, the inner bag 
delaminating from the outer shell and being shrunk with a decrease in contents, 
wherein the container body includes a bottom seal protrusion protruding from a 
bottom surface of a storage portion to store the contents, and the bottom seal 
protrusion is a sealing portion of, in blow molding using a cylindrical laminated 
parison provided with an outer layer constituting the outer shell and an inner 
layer constituting the inner bag, the laminated parison and is bent.  
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Patent AU-2019205936-B2 (AU)
Title: Methods for treating IL-6 mediated inflammation without immunosuppression
Inventor: DEVALARAJA MADHAV N
IPC: C07K16/24
Filed: 2019-01-04
Granted: 2022-09-15
Abstract: The disclosure provides methods of treating inflammation without inducing immune suppression. The method comprises administering a therapeutically effective amount of an IL-6 antagonist at a dose sufficient to reduce inflammation without causing immune suppression.