baber/WOPTO huggingface dataset:
Patent AU-766502-B2 (AU)
Title: Method for making complementary oligonucleotide tag sets
Inventor: WILLIAMS STEVEN R
IPC: C12Q1/6837
Filed: 1999-11-01
Granted: 2003-10-16
Abstract: The invention provides a method of synthesizing a repertoire of oligonucleotide tags comprising the steps of synthesizing a repertoire of oligonucleotide tag complements on one or more solid phase supports, cleaving a fraction of the oligonucleotide tag complements from the support(s), and inserting the cleaved tag complements into a cloning vector, as depicted in the figure. The cloned tag complements can conventionally be conjugated to selected polynucleotides to produce tagged polynucleotides having unique tag sequences which can be captured and sorted by hybridization to corresponding tag complements. Also provided are various reagents and components that are used or produced in the method.
Patent AU-585199-B2 (AU)
Title: Modified nucleotides, methods of preparing and utilizing and compositions containing same
Inventor: ENGELHARDT DEAN
IPC: C12Q1/68
Filed: 1983-06-23
Granted: 1989-06-15
Abstract: Disclosed is a protein to which a moiety capable of chelating an ion is directly or indirectly attached, said attachment being characterized in not interfering substantially with the ability of the moiety to chelate ions.
Patent AU-770907-B2 (AU)
Title: Ethylene polymerisation
Inventor: ALMQUIST VIDAR
IPC: C08F4/69
Filed: 2000-11-29
Granted: 2004-03-04
Abstract: Ths invention provides a process for the preparation of a polyethylene, in particular an HDPE suitable for blow moulding of HIC, which comprises polymerizing ethylene and, optionally an ethylenically unsaturated comonomer copolymerizable therewith, in the presence of a catalyst comprising a first silica-supported chromium catalyst having a pore volume of at least 2 mL/g, a surface area of at least 350 m<HIL><2</SP><PDAT>/g and a chromium content of 0.1 to 1.0% by weight and a second silica-supported chromium catalyst having a pore volume of at least 2 mL/g, a surface area of at least 450 m<HIL><2</SP><PDAT>/g and a chromium content of 0.1 to 1.0% by weight, wherein the silica support of said first catalyst also comprises alumina and the silica support of said second catalyst also comprises titanium, and preferably a co-catalyst.</PTEXT>
Patent AU-729268-B2 (AU)
Title: Composition for the oxidation dyeing of keratinous fibres containing a laccase and dyeing method using this composition
Inventor: LANG GERARD
IPC: A61K8/73
Filed: 1999-01-12
Granted: 2001-02-01
Abstract: The invention relates to a cosmetic mixture for the oxidation tinting of keratin fibres, containing in a support material suitable for tinting keratin fibres (a) at least one laccase-type enzyme; (b) at least one polymer thickener selected from the group constituted by: (i) amphiphilic non-ionic polymers comprising at least one fatty chain and at least one hydrophilic unit; (ii) anionic amphiphilic polymers comprising at least one hydrophilic unit and at least one fatty chain unit; (iii) cross-linked acrylic acid homopolymers; (iv) cross-linked 2-acrylamide-2-methyl-propane sulfonic acid homopolymers and their cross-linked acrylamide copolymers, which are partially or fully neutralized; (v) ammonium acrylate homopolymers or ammonium acrylate and acrylamide copolymers; (vi) dimethylaminoethyl-methacrylate homopolymers quatemized by methyl chloride or dimethylaminoethyl-methacrylate copolymers quaternized by methyl chloride and acrylamide copolymers; (vii) non-ionic guar gums; (viii) scleroglucan gum (a biopolysaccharide of microbial origin): (ix) gums made of vegetable exudates such as gum arabic, gum ghatti, gum karaya and gum tragacanth; and (c) at least one oxidation tint. The invention also relates to the tinting methods making use of the above mixture.
Patent AU-775345-B2 (AU)
Title: Surveillance and remote alarm system for persons subject to limitation of freedom of movement
Inventor: BOCCACCI ROBERTO
IPC: G07C9/00
Filed: 2000-12-13
Granted: 2004-07-29
Abstract: A surveillance and remote alarm system for persons subject to limitation of freedom of movement includes a fixed unit placed in the area within which the person can move and a personal bracelet element attached to the person subject to limitation of freedom of movement. The fixed unit is arranged to establish an electromagnetic connection with the personal element and a connection via a telephone line to an operations center. The fixed unit is equipped with a CPU associated with a fingerprint reader and a radio receiver arranged to interact with a similar radio transmitter fitted in the personal element together with a CPU that controls its operation. A sensor is provided to detect any interruption and/or anomalies in the connection between the fixed unit and the personal element and to send an alarm to the operations center.
Patent AU-743669-B2 (AU)
Title: Method and apparatus for electric arc welding
Inventor: STAVA ELLIOTT K
IPC: B23K9/02
Filed: 2000-03-15
Granted: 2002-01-31
Abstract: An electric arc welding apparatus for depositing molten metal from an advancing welding wire into a weld puddle in an open root between two juxtapositioned plates where the root extends in a welding path and is formed by converging walls terminating in generally parallel walls spaced to define a gap, which apparatus comprises a contact holder with a wire outlet, a switching power supply directing welding current to the wire as the wire passes from the outlet toward the open root, with the advancing wire defining an electrode stick out between the contact holder and the weld puddle, a circuit for sensing the length of the stick out, and control means for adjusting the welding current as a function of the sensed stick out length. <IMAGE>
Patent AU-778169-B2 (AU)
Title: Arrangement and method for forming a multilayered paper or paperboard web
Inventor: KINNUNEN JUKKA
IPC: D21F9/02
Filed: 2000-12-15
Granted: 2004-11-18
Abstract: The invention relates to an arrangement for forming a multilayered paper or paperboard web (D) from stock suspensions with papermaking fibres and fines, said arrangement including at least a first (101; 201; 301; 401; 501) and a second (102; 202; 302; 402; 502) forming unit, at least one of the forming units being of twin wire type and having a forming roll for forming a fibrous web (A or B) having a higher content of fines at one side (x or z) than at the other (y or w), and a couch device (117; 217; 316; 317; 416, 417) for couching together said fibrous web (A or B) having a higher content of fines at one side with an other fibrous web (B or A) to form the multilayered web (D), wherein both of the two forming units are of twin wire type and include a forming roll (109; 209; 309; 409; 509 and 111; 211; 311; 411; 511) for forming a fibrous web (A and B) having a higher content of fines at one side (x and z) than at the other (y and w), and that the two forming units (101; 201; 301; 401; 501 and 102, 202; 302; 402; 502) are so arranged relative to each other as to place the web sides (x and z) having the highest content of fines in contact with each other for couching together to form the multilayered web (D). The invention further relates to a method of forming a multilayered paper or paperboard web using said arrangement.
Patent AU-773378-B2 (AU)
Title: Drug targets in candida albicans
Inventor: CONTRERAS ROLAND HENRI
IPC: C12Q1/02
Filed: 1999-12-06
Granted: 2004-05-20
Abstract: The present invention is concerned with the identification of genes or functional fragments thereof from Candida albicans which are critical for growth and cell division and which genes may be used as selective drug targets to treat Candida albicans associated infections. Novel nucleic acid sequences from Candida albicans are also provided and which encode the polypeptides which are critical for growth of Candida albicans. Methods for the identification of anti-fungal compounds which inhibit fungal or yeast growth are also contemplated.
Patent AU-616619-B2 (AU)
Title: Method of and apparatus for controlling valve operation in an internal combustion engine
Inventor: FUJIYOSHI YOSHIHIRO
IPC: F01L1/34
Filed: 1988-11-18
Granted: 1991-10-31
Abstract: A method and apparatus for controlling valve operation in an internal combustion engine having a crankshaft driving a cam (8) for opening and closing an intake or exhaust valve (5) which is spring-biased in a closing direction. The method comprises the steps of varying the angular phase of the crankshaft and the camshaft (8) to control the timing of the opening of the valve (5) and releasing the force applied by the cam (9) to open the valve (5) while it is being opened to control the timing of the closing of the intake or exhaust valve (5). The apparatus includes a phase control mechanism (10) disposed between the crankshaft and the camshaft (8) and a lift control mechanism (11) disposed between the cam (9) and the intake or exhaust valve (5). Both mechanisms are hydraulically operated and controlled in response to engine operating conditions.
Patent AU-726163-B2 (AU)
Title: Hemostatic sponge based on collagen
Inventor: BIERING WOLFGANG
IPC: A61L15/44
Filed: 1997-04-02
Granted: 2000-11-02
Abstract: The invention relates to a hemostatic sponge based on collagen and an activator or proactivator of blood coagulation homogeneously distributed therein, which is dried and contains a water content of at least 2%, preferably in the range of 2 to 25%, more preferred 10 to 20%, and a method for producing this sponge.
Patent AU-783320-B2 (AU)
Title: Process of purification of hCG and recombinant hCG purified by that method
Inventor: PARADISI GIANFRANCO
IPC: G01N30/34
Filed: 2001-01-22
Granted: 2005-10-13
Abstract: A process for the purification of recombinant human Chorionic Gonadotropin (hCG) from a sample of crude recombinant hCG in the supernatant of CHO cells comprises the combined use of ion-exchange chromatography and reverse phase HPLC.  The ion-exchange chromatography is performed twice and the final use of a size exclusion chromatography allows the purification from any residual traces of contaminants. The specific bioactivity of the highly purified hCG obtained from the process is particularly high, amounting to about 25.000 IU/mg.
Patent AU-688916-B2 (AU)
Title: 7-0-ethers of taxane derivatives
Inventor: WONG HENRY S L
IPC: A61K31/337
Filed: 1995-07-27
Granted: 1998-03-19
Abstract: The present invention concerns taxane derivatives of formula I, <CHEM> wherein R<1> is hydrogen, C1-8 alkyloxy, C2-8 alkenyloxy, or C2-8 alkynyloxy, each can be optionally substituted with hydroxy; R is hydroxy, -OC(O)R<x> or -OC(O)OR<x>; R<4> and R<5> are independently C1-8 alkyl, C2-8 alkenyl, C2-8 alkynyl, or -Z-R<6>; p is zero or one; Z is a direct bond, C1-8 alkylene or C2-8 alkenediyl; R<6> is aryl, substituted aryl, C3-8 cycloalkyl or heteroaryl; and R<x> is C1-8 alkyl optionally, substituted with one to six same or different halogen atoms, C3-8 cycloalkyl or C2-8 alkenyl; or R<x> is a radical of the formula <CHEM> wherein D is a bond or C1-8 alkyl; and R<a>, R<b> and R<c> are independently hydrogen, amino, C1-8 alkylamino, di-C1-8alkylamino, halogen, C1-8 alkyl, or C1-8 alkyloxy, their use as antitumor agents and pharmaceutical compositions containing the novel compounds.
Patent AU-614812-B2 (AU)
Title: Hydrophilic oxygen permeable polymers
Inventor: BAMBURY RONALD E
IPC: C08F226/06
Filed: 1989-01-25
Granted: 1991-09-12
Abstract: A polymeric composition useful for forming biomedical devices, especially contact lenses, is formed by polymerizing a mixture comprising:     (a) a compound represented by the general formula: <CHEM> where R<1> and R<2> independently denote a hydrogen atom or an alkyl radical with one to six carbon atoms, and R<3> and R<4> independently denote alkyl radicals with one to six carbon atoms or a cycloalkyl radical with 5 or 6 carbon atoms; and   (b) an acrylate or methacrylate-functional polysiloxane monomer. p
Patent AU-662575-B2 (AU)
Title: Introducer assembly
Inventor: HOLMES JEFFREY E
IPC: A61B17/34
Filed: 1992-12-07
Granted: 1995-09-07
Abstract: The present invention relates to an introducer assembly (11) for introduction into a cavity of a patient having skin overlying the cavity and permitting the introduction of an instrument therethrough, and elongate tubular member (12) having a flow passage extending therethrough and having proximal (13) and distal (14) extremities, a flange (32) having top (47) and bottom (46) sides and having an inner margin (33) with an opening (34) therein through which the tubular member (12) extends with the proximal extremity (13) of the tubular member being disposed on the bottom side of the flange (32) and the tubular member (12) and permitting adjustment of the tubular member (12) longitudinally in said opening (34), a valve means (22) carried by the proximal extremity (13) of the tubular member (12) for inhibiting the flow of fluid through said flow passage from the distal extremity (14) to the proximal extremity (13) and permitting instruments to be inserted through the same while maintaining substantially fluid-tight seal and adhesive means (51) secured to the bottom side (46) of said flange (32) for engaging the skin of the patient for retaining the flange (32) in sealing engagement with the skin of the patient. <IMAGE>
Patent AU-560735-B2 (AU)
Title: Hydroxyethyl-azole derivatives
Inventor: HOLMWOOD GRAHAM
IPC: C07D249/08
Filed: 1984-09-21
Granted: 1987-04-16
Abstract: Hydroxyethyl-azole derivatives of the formula   <IMAGE>   in which R1 represents alkyl or the grouping Ar-Y-, Ar represents optionally substituted aryl, X represents a nitrogen atom or the CH group, Y represents a direct bond or the grouping -CH2-, -CH2CH2-, -OCH2-, -SCH2-, -CH=CH- or -C 3BOND C-, Z represents oxygen or the NOR2 group and R2 represents hydrogen, alkyl, alkenyl, alkynyl, optionally substituted aralkyl or optionally substituted cycloalkylalkyl, or addition products thereof with acids or metal salts, which possess fungicidal activity.
Patent AU-609605-B2 (AU)
Title: Intermediates for the preparation of novel substituted benzoselenino {4,3,2-cd} indazoles
Inventor: BERMAN ELLEN M
IPC: C07D517/06
Filed: 1989-05-01
Granted: 1991-05-02
Abstract: A benzoselenino[4, 3, 2-cd] indazole compound having in free base form the following general formula <CHEM>  amd the pharmaceutically acceptable salts thereof, wherein: R7, R8, R9 and R10 independently represent hydrogen, hydroxy or alkoxy of from one to four carbon atoms; R2 is ANR  min R sec  in which A is a straight or branched alkylene chain of from two to five carbon atoms, optionally substituted with hydroxyl and in which R min  and R sec  are independently a hydrogen, a straight or branched alkyl of from one to four carbon atoms, optionally substituted with hydroxyl or R min  and R sec  when taken together, represent the bifunctional radical <CHEM> in which n and m are each, independently, the integer 2 or 3 and B is a direct bond or O, S or NR''' wherein R''' is hydrogen or straight or branched alkyl of from one to four carbon atoms, optionally substituted with hydroxyl; and R5 is nitro, NH2, NHR2 or NHR''' min  wherein R''' min  is a one to four carbon atom acyl radical, a chloroacetyl radical,   -@-Z-NRxRy wherein Z is a straight or branched alkylene chain of from one to four carbon atoms and wherein Rx and Ry are each hydrogen, or a straight or branched alkyl of from one to four carbon atoms optionally substituted with hydroxy, R''' min  is the group <CHEM> Also disclosed are methods for their production and pharmaceutical compositions comprising the compounds. Compounds of the invention have pharmacological properties and are useful antibacterial agents, antifungal agents, and antitumor agents.
Patent AU-767812-B2 (AU)
Title: Shell-and-core dosage form approaching zero-order drug release
Inventor: BERNER BRET
IPC: A61K31/337
Filed: 2001-01-30
Granted: 2003-11-27
Abstract: Drugs are formulated as oral dosage forms for controlled release in which the release rate limiting portion is a shell surrounding the drug-containing core. The shell releases drug from the core by permitting diffusion of the drug from the core. The shell also motes gastric retention of the dosage form by swelling upon imbibition of gastric fluid to size that is retained in the stomach during the postprandial or fed mode.
Patent AU-685678-B2 (AU)
Title: Process for stabilising the direction indicated by magnetic compasses
Inventor: DITTRICH FRANK
IPC: G01C17/38
Filed: 1995-08-22
Granted: 1998-01-22
Abstract: A method is specified for stabilizing the directional display of magnetic compasses on bodies moving in a magnetic field, in particular the terrestrial magnetic field, against magnetic interference sources. The spatial components of the magnetic field vector are measured at a measuring point within a first interference-free measurement region. Taking account of the temporal changes in the measured components, the absolute value of the magnetic field strength and, as a function thereof, a quality function are determined, which quality function is a measure of the temporal distribution of the measured magnetic field vector components and a measure of the quality of the value of the magnetic field strength. For a further measuring point, the quality function and the measured component values are used to estimate the magnetic field vector at this measuring point and to measure the spatial components of this magnetic field vector. A further quality function is determined from the measurements which is combined with the first quality function to form a weighting function with which the components of the new magnetic field vector are weighted in such a way that a stabilized magnetic field vector having stabilized components is obtained. This method can be continued by iteration.
Patent AU-746905-B2 (AU)
Title: Temperature-dependent switch having a current transfer member
Inventor: HOFSASS MARCEL
IPC: H01H37/54
Filed: 1999-06-17
Granted: 2002-05-02
Abstract: The temperature-dependent switch has a temperature-responsive switch mechanism (11), with a movable current transfer element, contained within a housing (12) provided with a lower part (14) and an upper part (15) receiving a pair of stationary contacts (31,32) coupled to respective external terminals, with a resistance (38) connected across the stationary contacts contacted by the movable current transfer element.
Patent AU-747810-B2 (AU)
Title: System and method for automated collection and analysis of regularly retrieved patient information for remote patient care
Inventor: BARDY GUST H
IPC: G16H10/60
Filed: 2000-05-24
Granted: 2002-05-23
Abstract: A system and method for automated collection and analysis of regularly retrieved patient information for remote patient care is described. A set of collected measures (50) retrieved on a substantially regular basis is periodically received from a medical device (12,202,203,204) having a sensor for monitoring at least one physiological measure (71-78,207,210) or quality of life measure (208,211) of an individual patient (11,201). The collected measures set includes individual measures which each relate to patient information recorded by the medical device. The collected measures set is stored into a patient care record (205) for the individual patient within a database (17) organized to store one or more patient care records which each include a plurality (206,209) of the collected measures sets. One or more of the collected measures sets (206) in the patient care record for the individual patient is analyzed relative to one or more other collected measures sets (209) stored in the database to determine a patient status indicator (54). <IMAGE>
Patent AU-714877-B2 (AU)
Title: Food patty molding machine
Inventor: SOPER JAMES L
IPC: A22C7/00
Filed: 1997-07-24
Granted: 2000-01-13
Abstract: A food patty molding machine of the type utilizing a linearly reciprocable mold plate utilizes a direct rotary actuator drive which provides virtually direct linear transfer of the drive force to the ends of the linear drive shafts which support the mold plate. This results in the virtual elimination of high wear lateral loads. An encoder is directly linked to the rotary actuator drive shaft to provide accurate mold plate position signals which are utilized to control the operation of completely independently driven knock-out devices and to control operation of the feed ram during the feed stroke. Servo valve control of the hydraulic power unit which drives the rotary actuator and the feed ram cylinders also responds to suitably processed encoder signals to provide a wide range of speed and position control.
Patent AU-630614-B2 (AU)
Title: Subsaturated transdermal delivery device
Inventor: OSBORNE JAMES L
IPC: A61L15/44
Filed: 1989-06-13
Granted: 1992-11-05
Abstract: Subsaturated, rate controlled delivery devices (1) for delivering an agent (5). The initial equilibrated concentration of the agent in the agent reservoir (3) and the adhesive (5) is below saturation. The initial loading of the agent in reservoir (3) is sufficient to prevent the activity of the agent in the reservoir (3) from decreasing by more than about 75 % and preferably no more than about 25 % during the predetermined period of administration. The thicknesses of the adhesive (5), rate controlling membrane (4) and reservoir (3) layers are selected so that at least 50 % and, preferably at least 75 % of the initial equilibrated agent loading is in the reservoir layer (3). The devices (1) are usable to deliver agents which are liquid at body temperatures such as benzotropine, secoverine, nicotine, arecoline, polyethylene glycol monolaurate, glycerol monolaurate, glycerol monooleate and ethanol, for example.
Patent AU-702274-B2 (AU)
Title: New highly selective process for the preparation of enantiomerically pure phenyl-substituted 1,4-dihydropyridine-3,5-dicarboxylic acid derivatives
Inventor: MITTENDORF JOACHIM
IPC: C07D207/416
Filed: 1995-11-29
Granted: 1999-02-18
Abstract: 2-Benzylidene-3-oxo-butyric acid malimide esters(II), enantiomerically pure aminocrotonic acid malimide esters (IIIa) and enantiomerically pure acetoacetic acid malimide esters (VI) are new. Benzylidene compounds of formula (II), enantiomerically pure aminocrotonic acid esters of formula (IIIa) and enantiomerically pure acetoacetic acid esters of formula (VI) are new. [Image] R2>phenyl substituted by 1 or 2 of halo, CN, ethynyl, OCF3, SMe, NO2, CF3, 1-4C alkyl, 2-4C alkenyl, 2-4C alkynyl or 1-4C alkoxy; A : H or 1-8C alkyl; or phenyl or benzyl (both optionally substituted by 1-3 of OH, NO2, halo, CN, COOH, CF3, OCF3 or 1-6C alkoxy or by NR6>R7> or SO2R8>); R6>, R7>H, Ph or 1-5C alkyl; R8>1-4C alkyl or Ph. Independent claims are also included for: (1) the preparation of enatiomerically pure (II), (IIIa) and (VI); and (2) the preparation of diastereomeric 1,4-dihydropyridines of formula (IVa) or (IVb) by: (a) reacting enatiomerically pure (II) with aminocrotonic acid ester of formula Me-C(NH2)=CH-COOR1> (III) in a solvent, optionally in presence of base; or (b) reacting enatiomerically pure (IIIa) with benzylidene compound of formula R2>-CH=C(COMe)-COOR1> (IIa) in a solvent, optionally in presence of base. [Image] R1>1-8C alkyl (optionally substituted by 1-6C alkoxy) or 3-7C cycloalkyl.
Patent AU-699436-B2 (AU)
Title: Treatment of non-small cell lung carcinoma
Inventor: JOHNSON RANDALL KEITH
IPC: A61K31/475
Filed: 1995-12-14
Granted: 1998-12-03
Abstract: A method of treating non-small cell lung carcinoma in a human afflicted therewith which comprises administering to such human an effective amount of a compound of the water soluble camptothecin analog class.