baber/WOPTO huggingface dataset:
Patent CY-1120579-T1 (CY)
Title: Κυτταρα χρησιμα για προσδιορισμους δραστικοτητας αλλαντικης τοξινης οροτυπου α σε ανοσολογικη βαση
Inventor: JACKY BIRGITTE P S
IPC: G01N33/50
Filed: 2018-08-07
Abstract: Η παρούσα περιγραφή αποκαλύπτει κλωνικές κυτταρικές σειρές ευαίσθητες σε τοξίκωση ΒοΝΤ/Α, μεθόδους παραγωγής τέτοιων κλωνικών κυτταρικών σειρών και μεθόδους ανίχνευσης δραστικότητας Αλλαντικής τοξίνης ορότυπου Α με τη χρήση τέτοιων κλωνικών κυτταρικών σειρών.
Patent CY-1122690-T1 (CY)
Title: Διαδικασια για την παρασκευη βητα-3 αγωνιστων και ενδιαμεσων
Inventor: XU FENG
IPC: C07D207/12
Filed: 2019-10-09
Abstract: Η εφαρμογή αναφέρεται σε αποτελεσματικές και οικονομικές διαδικασίες, όπως περιγράφονται λεπτομερέστερα κατωτέρω, για την παρασκευή των βήτα 3 αγωνιστών του τύπου I-7 και των ενδιάμεσων ενώσεων που μπορούν να χρησιμοποιηθούν για την παρασκευή αυτών των αγωνιστών. Η παρούσα αποκάλυψη σχετίζεται με μια διαδικασία παρασκευής βήτα-3 αγωνιστών και ενδιαμέσων, χρησιμοποιώντας ένζυμα βιοκαταλύτη κετορεδουκτάσης (KRED) και μεθόδους χρήσης των βιοκαταλυτών.
Patent CY-1123728-T1 (CY)
Title: (2r,4r)-5-(5'-χλωρο-2'-φθοροδιφαινυλ-4-υλ) -2-υδροξυ-4- [(5-μεθυλοξαζολο-2-καρβονυλ) αμινο] πεντανοϊκο οξυ
Inventor: FLEURY MELISSA
IPC: C07D263/34
Filed: 2021-01-20
Abstract: Σε μια εκδοχή, η εφεύρεση αναφέρεται σε μια ένωση της δομής: (1), ή σε ένα φαρμακευτικώς αποδεκτό άλας αυτής της ένωσης, που έχει δραστηριότητα αναστολής της νεπριλυσίνης. Σε μια άλλη εκδοχή, η εφεύρεση αναφέρεται σε φαρμακευτικές συνθέσεις που περιέχουν αυτή την ένωση, σε μεθόδους χρήσης αυτής της ένωσης, και σε διαδικασίες για τη παρασκευή αυτής της ένωσης.
Patent GR-980300029-T1 (GR)
Title: Orphan receptor
Inventor: KUIPER GEORGE G J M
IPC: A61P19/10
Filed: 1998-04-30
Abstract: This invention relates to a novel estrogen receptor-related nuclear receptor, hereinafter termed "ER beta " having the amino acid sequence of Figs. 1, 13A or 14A or substantially the same amino acid sequence as the amino acid sequence shown in Figs. 1, 13A or 13B or an amino acid sequence functionally similar to that sequence. The invention also relates to DNA sequences encoding the receptor. The receptor may be useful in isolating molecules for the treatment of disorders such as prostate cancer, benign prostatic hyperplasia, osteoporosis or cardiovascular disorders and in the testing of substances for estrogenic and other hormonal effects.
Patent SI-1294996-T1 (SI)
Title: System of relatively planar components
Inventor: KNAUSEDER FRANZ
IPC: E04F15/00
Filed: 2001-06-01
Abstract: A covering comprises panels (9, 9') having jointing elements (91, 92) on the side provided with adhesive (96) which may be transformed from a passive to an active state. Independent claims are also included for: (i) a process for the production of panels (100, 100') for coverings or cladding, preferably for floor covering, by application by co-extrusion of an adhesive bead (96) and/or a bead of an adhesive polymer core (961), activated by liquid, preferably water, encased in a sheath (962) of a water-, moisture and/or solvent resistant and impermeable, flexible polymer preferably a synthetic polymer, preferably based on polyvinyl acetate or a biopolymer onto side grooves (92), preferably onto at least one of the side faces (921, 922) and/or the tongues (91), preferably onto at least one of the side faces (911, 912) and (ii) a machine (100) for the application of a core (961) and sheath (962) adhesive bead by co-extrusion via a core nozzle (102) and concentrically arranged ring nozzle (212) onto the groove and/or tongue of a panel.
Patent SI-1725787-T1 (SI)
Title: Jointing elements incorporated into the ends of a conveyor belt
Inventor: JAKOB HORST
IPC: B65G15/00
Filed: 2005-03-17
Abstract: A junction for a conveyor belt that includes first and second half-junctions attachable to one end of the conveyor belt. Each of the half-junctions having substantially matching shapes that allow the half-junctions to be interlinked. The half-junctions include a flexible core, and being respectively equipped with cup inserts and bush inserts allowing the passage of an assembly mechanism. Each of the cores extend towards the inside of each half-junction forming a fold at a free edge of each of the half-junctions. The top level of the first half-junction contains the fold and in which a front edge of the bottom level has substantially the same shape as a front edge of the top level, but is shifted towards the rear at least by the distance that separates the front edge of the top level from the cup inserts that are the furthest from the front edge of the top level. The second half-junction has a top level in which the shape of a front edge of the top level matches that of the front edge of the matching first half-junction, and a bottom level containing the fold and the bush inserts. The front edge of the bottom level is shifted towards the front in relation to the front edge of the top level, and its shape matches that of the front edge of the bottom level of the first half-junction. The attachment of the first and second half-junctions with each other is provided by fasteners.
Patent SI-2132195-T1 (SI)
Title: Acetone solvate of phthaloyl amlodipine
Inventor: BERENGUER MAIMO RAMON
IPC: C07D401/00
Filed: 2008-03-28
Abstract: The present invention is directed to an acetone solvate of phthaloyl amlodipine, its use in the synthesis of amlodipine and a process for its preparation which comprises dissolving phthaloyl amlodipine in acetone and cooling the mixture.
Patent DE-3687543-T2 (DE)
Inventor: STEWART WILLIAM JAMES
IPC: G01N33/553
Filed: 1986-04-10
Granted: 1993-05-13
Abstract: An optic-waveguide biosensor (fig 2) of the type comprising an optic-waveguide (1) provided with a coating (7) sensitized to a specific assay species, and input and output coupling members (3) and (5). Light signal response is enhanced by incorporating a partially reflecting, partially transmitting, low refractive index medium (15) between each coupling member (3,5) and the waveguide (1). The thickness of this medium (15) is chosen so that light may be coupled by frustrated total internal reflection and so that the medium (15) serves as a resonant mirror. It may be in the form of a single layer (fig 3(a)) formed of eg. magnesium fluoride or alumina material. Alternatively, it may be of multilayer structure dielectric material (fig 3 (b)).
Patent DE-3689491-T2 (DE)
Inventor: KATO YUKIO OMRON TATEISI ELECT
IPC: G06F11/30
Filed: 1986-02-14
Granted: 1994-08-11
Abstract: A monitor circuit comprises a data storage having a dummy data stored therein, buffer circuit connected to the output of the data storage, coincidence circuit for compairing the data on the I/O bus connected between the buffer circuit and I/O units with the dummy data of the data storage, and flag circuit for setting an abnormal flag responsive to the non-coincidence output from the coincidence circuit. During the I/O refresh of a PC such abnormal flag is set due to the disturbance of the I/O bus. The I/O refresh is repeatedly performed in the event the flag is set.
Patent DE-3751042-T2 (DE)
Inventor: TABOR STANLEY
IPC: C12Q1/68
Filed: 1987-12-24
Granted: 1995-05-24
Abstract: The invention relates to methods of DNA sequencing including a method for determining the nucleotide base sequence of a DNA molecule, comprising providing the DNA molecule annealed with a primer molecule able to hybridize to the DNA molecule,   incubating the annealed mixture with a DNA polymerase, except reverse transcriptase, in the presence of four different deoxynucleoside triphosphates and a chain terminating agent which terminates DNA synthesis at a specific nucleotide base, the concentration of all four deoxynucleoside triphosphates at the start of said incubating being sufficient to allow DNA synthesis to continue until terminated by said agent. The DNA products of the incubating reaction are separated according to their size, so that at least a part of the nucleotide base sequence of the DNA molecule can be determined. In a furter embodiment the primer may be extended and labelled prior to the incubating reaction.
Patent DE-3854581-T2 (DE)
Inventor: WANDS JACK
IPC: C07K19/00
Filed: 1988-12-09
Granted: 1996-06-13
Abstract: The present invention pertains to the SF-25 antigen of colon adenocarcinoma cells, to functional derivatives of this antigen, and to antibodies and antibody fragments capable of binding this antigen. The invention further discloses methods of diagnosing and treating colon cancer which employ the above molecules.
Patent DE-3856244-T2 (DE)
Inventor: BROCKLEHURST CHARLES E
IPC: D05B25/00
Filed: 1988-10-20
Granted: 1999-04-22
Abstract: Segments (35) of flexible sheet material (30) are continuously and progressively conveyed through a series of work stations (34, 40). Each segment (35) of the sheet material (30) is advanced along its length from a first work station (34) to a second work station (40) at a first rate of movement. The leading edge portion (14) of the segment (35) is advanced through the second work station (40) at a rate of movement slower than the first rate of movement. A portion of the segment (35) trailing the leading edge (14) is temporarily accumulated at a position between the first and second work stations (34, 40) until the segment (35) is advanced through the second work station (40). <IMAGE>
Patent DE-3875069-T2 (DE)
Inventor: LUDLOW IAN KEITH
IPC: G01N15/02
Filed: 1988-11-10
Granted: 1993-03-25
Abstract: An apparatus and method which provides a measure of the asymmetry as well as the size of individual fluid borne particles. Laser-light scattering techniques are employed to obtain data on the particles, which is then compared to data on known particle shapes to ascribe an asymmetry factor to the particles.
Patent DE-3884749-T2 (DE)
Inventor: HEINE GUNTHER KARL
IPC: H02K37/14
Filed: 1988-11-01
Granted: 1994-05-05
Abstract: A single-housing stepper motor is disclosed comprising a rotor (14) and stator (16) both mounted in a single housing (10) (which may be a part of the base casting) the bearings (40, 42) supporting the rotor for rotation within the housing both being located on the rotor shaft on the same side of the rotor adjacent one another, the opposite end of the single housing being covered with a sealed plastic cover (44). The lamination stack (18) that forms the stator is piloted by machined surfaces (30, 32) into a high tolerence fit within the housing (10), and clamped in place with a simple wave washer/snap ring combination (66, 68). The stator laminations are designed with a decagonally interrupted periphery which can be used without changing the area of the poles (20), and allow space for the wires to the poles to be lead out past the lamination stack. A sealing plastic cover (44) is provided with a special pressure finger (60) to hold the wires (36) running to the stator coils away from the sharp edges of the stack wave spring and snap ring; the cover is also specially designed to capture the wires to relieve the strain on the wires. Alternatively (Fig. 5), the bearings (104, 106) may be located on opposite sides of the rotor (14), the stator (16) is piloted into a precisely aligned position on an inner wall of the housing adjacent the front bearing (104), the other end of the stack being held in place by a bearing holder (116) interposed between the rear bearing (106) and the edge of the stator (16), the holding forces being precisely defined to accurately align the stator with the rotor of the stepper motor. The entire assembly, including the rear bearing, bearing holder and stator support, as well as the stator is held together with a star-shaped spring (15)) comprising a plurality of fingers (106A-D) that slide into and rotate within slots (158A-D) in the housing in a bayonet arrangement. These slots allow insertion of the star-shaped spring under pressure, and rotation under pressure within the groove (160) to a seated position. The same groove then accepts the (160) to a seated position. The same groove then accepts the encapsulating plastic cover (170), preferably inserted through the same openings as the bayonet arms of the spring, though being rotated in the opposite direction.
Patent TR-199802166-T2 (TR)
Inventor: AMPULSKI ROBERT STANLEY
IPC: D21H27/02
Filed: 1997-04-25
Abstract: Kagit yapiminda kullanilan bir gereç. Gereç, bir keçe ve buna eklenen bir desen kalibindan olusmaktadir. Keçe, göreli olarak yüksek UV emme özelligine sahiptir. Böyle bir yüksek UV emme özelligi, aktinik isigin, kurutmak amaciyla desen kalibinin yüzeyine verildiginde dagilmasini önler. Isigin desen kalibinin alt kismina dogru dagilmasi sinirlandirilarak, keçenin desen kalibina ait parça bulunmasi istenmeyen kisimlarinda bu tür parçalarin kuruyup kalmasi önlenir.
Patent TR-199900066-T2 (TR)
Inventor: REITER LAWRENCE ALAN
IPC: C07F9/36
Filed: 1997-06-30
Abstract: Artrit, kanser, sitotoksik antikanser ajanlar ile sinerji, doku ülserasyonu, maküler dejenerasyon ( beneklenme), restenozis (genisletilmis bir kanalin tekrar daraltilmasi), periodontal hastaliklar, epidemolizis bulloza, skleritten (sklera iltihabi) meydana gelen gruptan seçilen bir gruptan seçilen bir durumun tedavisinde yararli olan, standart NSAID'lar ve analjezikler ile kombinasyon halinde ve AIDS, sepsis, septik sok ve TNF üretimini içine alan diger hastaliklar, matriks metalloproteinaz aktivite ile karakterize olan diger hastaliklarin tedavisinde yararli olan, R1, R2, R3, R4, R5, R6 ve Ar'nin, yukarida tarif edildigi gibi oldugu, formül (I)'in bir bilesigi.
Patent TR-199900902-T2 (TR)
Title: Çamasir suyu, sülfamik asit, ve bir polikarboksilat polimer içeren bir temizleme bilesimi.
Inventor: SIRIANNI GIUSEPPE
IPC: C11D3/26
Filed: 1997-10-06
Abstract: Bir halojen çamasir suyu ve bir organik veya inorganik -NH2 bilesigi ve bir polikarboksilat polimerik bilesik içeren bir temizleme bilesimi saglanmaktadir, böylece azaltilmis deri tahrisi ve etkili kötü çamasir suyu kokusu azaltilmasi elde edilmistir.
Patent TR-199901801-T2 (TR)
Inventor: LEIJON MATS
IPC: H02K3/48
Filed: 1998-02-02
Abstract: Bir dönen elektrik makinesi içindeki statörün mekanik bükülmezligi ve dogal frekansinin arttirilmasi için bir cihaz olup, statör, sarimi tutan yariklar arasinda statör disleri ile donatilmistir, statör dislerinin serbest uçlari statör ve rotor arasindaki hava boslugu içinde konumlandirilmistir, bahsedilen cihaz, statör dislerinin teget yönünde mekanik biçimde yerine sabitlenmesi amaciyla her statör yarigina karsi düzenlenmis, bitisik statör disleri ile tek parça halinde olusturulmus en azindan bir boyunluk kismina sahip bulunmaktadir.
Patent TR-199901953-T2 (TR)
Inventor: BOLD GUIDO
IPC: C07D401/12
Filed: 1998-02-11
Abstract: Bulus formül (I) bilesikleri ile ilgilidir; içerisinde r 0-2' dir; n 0-2' dir; m 0-4' dür; R1 ile R2 (i) her durumda düsük alkildir, veya (ii) birlikte alt formül (I*) içinde bir köprü olustururlar; veya (iii) birlikte alt formül (I*) içinde bir köprü olustururlar; içerisinde T1,T2,T3 ve T4 zincir üyelerinden bir ya da iki tanesi nitrojen olarak bulunur ve kalanlar her durumda CH' dir; A, B, D ve E N veya CH'dir; içerisinde bu radikallerden iki tanesinden daha fazlasi N degildir; Gdüsük alkilen, asiloksi-veya hidroksi-düsük alkilen, -CH2-O-,-CH2-S-,-CH2-NH-, oksa, tia veya imino olarak bulunur; Q metildir; R H veya düsük alkildir.
Patent TR-199902987-T2 (TR)
Inventor: MEILLER HERMANN
IPC: B60N2/64
Filed: 1998-04-03
Abstract: Bulus, kullanicinin sirtini destekleyecek ve kullanicinin sirt egimini ayarlayacak sekilde rotatif bir eksen (14) etrafina döndürülebilen, düz bir kesimi (10) olan bir koltukta, özellikle bir otomobil koltuguyla ilgilidir. Bulusa göre koltugun sirt destegi rotatif bir ekseni (14) çevreleyen yarim boru (12) seklindedir. Bu boru kullanici sirti için destegin düz (10) ile tek parça halindedir.
Patent DE-60004279-T2 (DE)
Inventor: DE LONGHI GIUSEPPE
IPC: F24H3/00
Filed: 2000-01-17
Granted: 2004-06-17
Abstract: The independently operating mobile radiator comprising a body having a plurality of radiating members each defined by at least a first metal plate and a second metal plate mutually associated and by at least one central portion wherein fluid heated by heating means, circulates at a preset temperature, said radiating members being mutually connected through passage hubs for said heated fluid for its circulation inside said body which, in at least one region of the surface of the radiating members, external to said central portion wherein said heated fluid circulates, further has additional heating means at least for heating the surrounding air. <IMAGE>
Patent DE-60011219-T2 (DE)
Inventor: KOSKI ILPO
IPC: D21F3/02
Filed: 2000-04-12
Granted: 2005-06-23
Abstract: A press for the dewatering of a fiber web, comprising a roll, a counterpart and and an endless press belt adapted to glide around the counterpart. Into the concave press zone region of the counterpart, a flexible press plate is adapted, anchored to the counterpart at the leading edge of the counterpart, relative to web motion. Beneath the press plate, hydrostatic pressure chambers are provided, separated from each other by means of flexible pressure lines. By individually controlling the pressures of the chambers, the leads and optionally the press plate edges, a desired pressure profile is obtained across the extended pressure zone.
Patent DE-60012652-T2 (DE)
Inventor: LANSARDIERE GUY
IPC: E05F5/00
Filed: 2000-10-16
Granted: 2005-07-28
Abstract: The hydraulically braked hinge for a building door has a fixed section (2) and a movable section (3) rotating around an axis (4) and controlled by a braking cartridge in cavities in the hinge sections. The cartridge has a cylinder (5) with an external rib (7) engaging a groove (8) in the movable section. An axis pin (16) has a channelled shaft (17) carrying a piston (30) with fluid flow damping passages (35).
Patent DE-60020159-T2 (DE)
Inventor: CORMIER MICHEL J N
IPC: A61M35/00
Filed: 2000-12-07
Granted: 2005-10-06
Abstract: An expandable skin stretching device includes skin engaging opposite ends that contact the skin surface on opposite sides of an area of the skin surface having micropathways therein. When the skin stretching device is expanded the skin between the opposite ends is placed under tension, i.e., stretched. The skin is placed under a tension of about 0.01 to about 10 megapascals, preferably about 0.05 to about 2 megapascals. The skin stretching can be unidirectional or multi-directional. Alternative embodiments of skin stretching devices use suction or normal force to stretch the skin. Stretching the skin helps keep the micropathways open for enhanced agent (e.g., drug) delivery through the micropathways. The stretching also delays micropathway closure.
Patent DE-60023691-T2 (DE)
Inventor: GLIMCHER H
IPC: C12N1/21
Filed: 2000-06-01
Granted: 2006-10-19
Abstract: Isolated nucleic acid molecules encoding T-bet, and isolated T-bet proteins, are provided. The invention further provides antisense nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced and non-human transgenic animals carrying a T-bet transgene. The invention further provides T-bet fusion proteins and anti-T-bet antibodies. Methods of using the T-bet compositions of the invention are also disclosed, including methods for detecting T-bet activity in a biological sample, methods of modulating T-bet activity in a cell, and methods for identifying agents that modulate the activity of T-bet.
Patent DE-60024455-T2 (DE)
Inventor: BESTERMAN M
IPC: A61P31/04
Filed: 2000-07-05
Granted: 2006-08-03
Abstract: The intention relates to bacterial antibiotic resistance and, in particular, to compositions and methods for overcoming bacterial antibiotic resistance. The invention provides novel beta-lactamase inhibitors, which are structurally unrelated to the natural product and semi-synthetic beta-lactamase inhibitors presently available, and which do not require a beta-lactam pharmacophore. The invention also provides pharmaceutical compositions and methods for inhibiting bacterial growth.
Patent DE-60026487-T2 (DE)
Inventor: POTSTADAN REYNALDO M
IPC: F16B39/284
Filed: 2000-08-29
Granted: 2006-11-23
Abstract: A pushnut fastener having a substantially planar base portion from which a cylindrical sleeve is drawn and internally threaded. A pair of angled leg portions extending from opposing lateral edges of the base portion, each including a laterally extending tab partially extending into a space formed between said leg portions for engaging threads of a mating male fastener. The leg portions are preferably defined by inner and outer leg sections, each outer leg section including an inwardly angled section which engages the edges of a mounting hole of a panel into which the pushnut is seated during assembly.
Patent DE-60032520-T2 (DE)
Inventor: KANO FUMIHIKO
IPC: C07C309/73
Filed: 2000-11-24
Granted: 2007-10-04
Abstract: Sulfonic acid ester derivatives represented by the general formula (4) or (5) are produced by reacting an amino alcohol derivative represented by the general formula (1) or (2) with an organic sulfonyl halide represented by the general formula (3), in a mixed solvent composed of an aprotic organic solvent and water in the presence of a non -water-prohibiting inorganic base. This procedure can be carried out in a simple, easy, safe and economical manner while reducing the load on the environment. <CHEM> Wherein n represents an integer of 0 to 5, A represents a phenyl group, which may be substituted, R represents a methanesulfonyl, ethanesulfonyl, p-toluenesulfonyl or p-nitrobenzenesulfonyl group and X represents a chloride, bromine or iodine atom.
Patent DE-60033925-T2 (DE)
Inventor: RYGAS TEDEUSZ P
IPC: B01J31/22
Filed: 2000-05-11
Granted: 2008-01-10
Abstract: A process for preparing a haloalkane comprising: (a) contacting a haloalkane starting material with a haloalkene starting material in the presence of an effective amount of a catalyst complex under conditions effective to facilitate an addition reaction and to form a product stream comprising a haloalkane product from said addition reaction, wherein said catalyst complex has a boiling point higher than that of said haloalkane product; and (b) recovering said haloalkane product from said product stream.
Patent DE-60034356-T2 (DE)
Inventor: MASUI KENJI
IPC: A23L27/60
Filed: 2000-08-23
Granted: 2007-12-20
Abstract: Described is a fat or oil composition which comprises at least 35 wt.% of a diacylglycerol, the constituent fatty acids of said diacylglycerol satisfying the following equation: (an amount of a cis-form unsaturated fatty acid) / (an amount of a saturated fatty acid + an amount of a trans-form unsaturated fatty acid) ¥ 6. Usual intake of the fat or oil composition of the present invention as an edible oil makes it possible to reduce arteriosclerotic factors in blood, leading to the prevention of arteriosclerosis, furthermore, various degenerative diseases.
Patent DE-60035891-T2 (DE)
Inventor: PADOVANI ROBERTO
IPC: H04B1/707
Filed: 2000-10-31
Granted: 2008-04-24
Abstract: An apparatus for transmitting pilot references from a plurality of transmission sources, comprises a receiver for receiving, at each transmission source, one or more signals indicative of a time reference for the communication system. The apparatus generates, at each transmission source, a plurality of pilot bursts for a pilot reference; and transmits the plurality of pilot bursts in synchronization with the time reference from each transmission source.