baber/WOPTO huggingface dataset:
Patent MX-2020002726-A (MX)
Title: Pentosan polysulfate and method for producing pentosan polysulfate.
Inventor: ISHIKAWA KOTARO
IPC: A61P7/02
Filed: 2018-09-11
Abstract: The present invention provides a pentosan polysulfate which has a uronic acid content of from 0.0% by mass to 6.0% by mass, preferably a pentosan polysulfate which has a structure represented by general formula I, a pharmaceutically acceptable salt of one of these pentosan polysulfates, or a pharmaceutically acceptable solvate of one of these pentosan polysulfates. In the formula, each R represents a hydrogen atom, -COCH<sub>3</sub> or -SO<sub>3</sub>X, and at least one R represents -SO<sub>3</sub>X; X represents a hydrogen atom, or a monovalent or divalent metal; X represents a hydrogen atom, or a monovalent or divalent metal; and n represents an integer of from 1 to 30 (inclusive). The present invention also provides a method for producing a pentosan polysulfate, which sequentially comprises a step for obtaining a neutral xylo-oligosaccharide by depolymerizing a plant-derived starting material and a sulfation step of the neutral xylo-oligosaccharide in this order.
Patent MX-2020005577-A (MX)
Title: Anonymous dna / rna biospecimen follow-up process, anonymous dna / rna biospecimen follow-up system, and an anonymous dna / rna biospecimen extraction kit using public cifrication and biospecimen relyming infrastructure, associated cifrication chain claim ownership, give consent to use, and keep tracking of corresponding data sets.
Inventor: URIBE BENITEZ DANIEL FRANCISCO
IPC: G06N3/12
Filed: 2020-07-13
Abstract: An anonymous DNA / RNA biological sample tracking process, an anonymous DNA / RNA biological sample tracking system, and an anonymous DNA / RNA biospecimen kit using public key, asymmetric encryption, and chain encryption infrastructure are described. of blocks to relate, claim ownership, consent to use and keep track of the corresponding multi-omic data sets collected by means of the anonymous DNA / RNA biospecies kit. By using public key encryption infrastructure, asymmetric encryption, and blockchain technology, it is possible to track genomic / multi-omic data and genomic / multi-omic reports related to a biological sample obtained through the Anonymous DNA / RNA biospecimen tracking kit without the need to reveal personal information.
Patent MX-2020007311-A (MX)
Title: Breakable locking cap for a container comprising a neck.
Inventor: REY GAËTAN
IPC: B65D41/00
Filed: 2020-07-13
Abstract: The invention relates to a locking cap for a container comprising a neck, intended to block a stopper in the neck of the container and comprising: an external body having a breakable part, a cage that is configured to fit into and lock axially in the external body, and having a breakable zone, the cage further comprising: an upper ring, a plurality n of branches that are connected to the upper ring and define therewith a generally cylindrical shape, n/2 first bridges and n/2 second bridges, each interconnecting two adjacent branches, at least one opening tab, which is supported by a second bridge, which is inclined toward the outside of the cage and is oriented toward the upper ring, the opening tab being adjacent to the breakable zone, which is located on the second bridge.
Patent MX-2020007403-A (MX)
Title: Tetrahydroisoquinoline compounds.
Inventor: VEGA GARCÍA MIGUEL
IPC: A61P35/00
Filed: 2019-01-10
Abstract: The present invention relates to a novel class of tetrahydroisoquinoline compounds of formula I and to compositions comprising the same. The compounds and compositions of the present invention can be used as medicaments in the treatment of cancer.
Patent MX-2020008148-A (MX)
Title: Disc screen for separating solid materials.
Inventor: CAPPOZZO DOMENICO
IPC: B07B13/00
Filed: 2020-07-31
Abstract: A disc screen for separating solid residues which comprises multiple parallel rotation shafts, each of which carrying, fixed thereto, a plurality of discs. The lateral faces of the aforesaid discs are provided with thrust wings having curved section, which are adapted to intercept components of the material to be screened, in particular light or filamentous materials, in order to expel them outside the interspaces between the discs, so as to prevent possible tangling and obstruction of such materials at the rotation shafts.
Patent MX-2020008447-A (MX)
Title: Use of 5-fluoro-4-(4-fluoro-2-methoxyphenyl)-n-{4-[(s-methylsulfo nimidoyl)methyl]pyridin-2-yl}pyridin-2-amine for treating diffuse large b-cell lymphoma.
Inventor: SCHOLZ ARNE
IPC: A61K31/4427
Filed: 2019-02-12
Abstract: The present invention relates to the use of 5-Fluoro-4-(4-fluoro-2-methoxyphenyl)-N-{4-[(S- methylsulfonimidoyl)methyl]pyridin-2-yl}pyridin-2-amine (compound A), more particularly (+)5- Fluoro-4-(4-fluoro-2-methoxyphenyl)-N-{4-[(S-methylsulfonimidoy l)methyl]pyridin-2-yl}pyridin-2- amine (compound AÂ´), for treating diffuse large B-cell lymphoma (DLBCL), especially in germinal- centre B-cell type of diffuse large B-cell lymphoma and especially in diffuse large B-cell lymphoma which cells have an amplification or translocation of the MYC gene and/or BCL2 gene and/or an overexpression of MYC and/or BCL2.
Patent MX-2020009299-A (MX)
Title: Composition for a powder mortar and a powder mortar, in particular for use as a spackling compound.
Inventor: BERNETH CLAUS-PETER
IPC: C04B26/28
Filed: 2019-01-17
Abstract: The invention relates to a composition for a powder mortar comprising one or more fillers, one or more binders, one or more thickeners and optionally further additives, wherein at least one of the one or more binders comprises a starch, and wherein at least one of the one or more thickeners is an etherified starch. The invention further relates to a corresponding powder mortar, in particular for use as a spackling compound.
Patent MX-2020009639-A (MX)
Title: Peptide vaccines against interleukin-31.
Inventor: BAMMERT GARY FRANCIS
IPC: A61K47/64
Filed: 2019-03-18
Abstract: A vaccine composition for immunizing and/or protecting a mammal against an IL-31 mediated disorder is provided, wherein the composition includes: the combination of a carrier polypeptide and at least one mimotope selected from a feline IL-31 mimotope, a canine IL-31 mimotope, a horse IL-31 mimotope, and a human IL-31 mimotope; and an adjuvant. Such vaccines can be in the form of pharmaceutical compositions useful for treating or protecting mammals such as cats, dogs, horses, or humans against IL-31 -mediated disorders.
Patent MX-2020009945-A (MX)
Title: High-strength steel plate and high-strength zinc-plated steel plate.
Inventor: NAKAYA MICHIHARU
IPC: C21D9/46
Filed: 2019-03-11
Abstract: A high-strength steel plate according to one embodiment of the present invention satisfies a prescribed chemical component composition, and is characterized by: exhibiting a martensite content of at least 93 vol%, a total combined content of ferrite, pearlite and bainite of 2 vol% or less, and a retained austenite content of 7 vol% or less relative to the metal structure overall; having at least 240 martensite laths when measuring a total length of 300Î¼m via a sectioning method in an image obtained by observing the metal structure using a scanning electron microscope; and exhibiting a tensile strength of at least 1,470MPa.
Patent MX-2020010268-A (MX)
Title: Prosthetic heart valve and delivery apparatus.
Inventor: BAKIS GEORGE
IPC: A61F2/966
Filed: 2016-06-01
Abstract: The present disclosure is directed to embodiments of catheter-based prosthetic heart valves, and in particular, prosthetic heart valves having sealing members configured to seal the interface between the prosthetic valve and the surrounding tissue of the native annulus in which the prosthetic valve is implanted. The present disclosure also discloses new methods of making an introducer sheath with an inner liner for percutaneous insertion of a medical device into a patient.
Patent MX-2020010715-A (MX)
Title: Lixisenatide synthesis with capping.
Inventor: HENKEL BERND
IPC: C07K1/06
Filed: 2019-04-10
Abstract: The present invention relates to a method for the synthesis of a polypeptide comprising a pre-determined amino acid sequence. The method according to the invention comprises coupling cycles of coupling an N-terminally protected amino acid building block C-terminally at an unprotected N-terminal amino group of an amino acid chain, wherein at least one coupling cycle comprises a coupling step (a), a capping step (b), and a de-protecting step (c).
Patent MX-2020013288-A (MX)
Title: Alkoxylated alkyl amine polyesters as pour point depressants for fuels.
Inventor: ZHAO HAIBO
IPC: C10L1/222
Filed: 2019-06-06
Abstract: The present disclosure provides a pour point dispersant composition comprising an alkoxylated alkyl amine polyester. The pour point depressant composition may optionally be combined with a solvent and added to a hydrocarbon composition to improve the cold-flow properties of the hydrocarbon composition.
Patent MX-2021001646-A (MX)
Title: Binding machine.
Inventor: YOSHIDA YUSUKE
IPC: E04G21/12
Filed: 2021-02-10
Abstract: A binding machine includes: a wire feeding unit; a curl fortning unit; a cutting unit; a binding unit; a motor; and a control unit. The binding unit includes: a rotary shaft to be driven by the motor; a wire engaging body configured to engage the wire and to rotate together with the rotary shaft, thereby twisting the wire; and a rotation regulation part configured to regulate rotation of the wire engaging body. The control unit is configured to control stop of the motor rotating in a direction of twisting the wire, based on a position in a rotation direction of the wire engaging body and a position at which the rotation of the wire engaging body can be regulated by the rotation regulation part.
Patent MX-2021001945-A (MX)
Title: Head for an oral care implement and a kit comprising such head.
Inventor: JUNGNICKEL UWE
IPC: A46B9/02
Filed: 2019-08-22
Abstract: A head for an oral care implement has an elongated mounting surface with an outer circumference, a longitudinal axis extending between a proximal end attached to, or being repeatedly attachable to and detachable from a handle, and a distal end opposite the proximal end. The head comprises two outer rows of tufts extending from the mounting surface along the longitudinal axis in proximity to the outer circumference, and an arc-shaped toe arranged at the distal end and being composed of filaments or a plurality of tufts of filaments arranged in an arc-shaped manner. The tufts of the outer rows have a longitudinal extension and a cross-sectional area extending substantially perpendicular to the longitudinal extension and the cross-sectional area having an elongated shape with a longer axis and a shorter axis. The tufts of the outer rows are arranged in a manner that the longer axis defines an angle Î± of from about 20Â° to about 65Â°, preferably from about 30Â° to about 50Â°, more preferably about 45Â° with respect to the longitudinal axis of the head, so that the tufts of the outer rows and the arc-shape toe define an outer arc-shaped envelope.
Patent MX-2021003990-A (MX)
Title: Methods for screening ubiquitin ligase agonists.
Inventor: ZHENG NING
IPC: G01N33/53
Filed: 2019-10-17
Abstract: Disclosed herein are methods for identifying a ubiquitin ligase agonist, and the methods include (a) contacting a ubiquitin ligase with a candidate agonist and a neo-substrate; and (b) determining whether the candidate agonist is effective to result in binding the ubiquitin ligase to the neo-substrate, wherein binding of the ubiquitin substrate to the neo- substrate identifies the candidate agonist as a ubiquitin ligase agonist.
Patent MX-2021004932-A (MX)
Title: Oligonucleotide compositions and methods of making the same.
Inventor: RAMIYA PREMCHANDRAN H
IPC: C12N15/113
Filed: 2016-10-28
Abstract: The present disclosure provides a solid phase method of making oligonucleotides via sequential coupling cycles including at least one coupling of a dinucleotide dimer subunit to a free 3'-terminal group of a growing chain. The oligonucleotides include at least two nucleoside subunits joined by a N3'âP5' phosphoramidate linkage. The method may include the steps of (a) deprotecting the protected 3' amino group of a terminal nucleoside attached to a solid phase support, said deprotecting forming a free 3' amino group; (b) contacting the free 3' amino group with a 3'-protected amino-dinucleotide-5'-phosphoramidite dimer in the presence of a nucleophilic catalyst to form an internucleoside N3'âP5' phosphoramidite linkage; and (c) oxidizing (e.g., sulfurizing) the linkage. The compositions produced by the subject methods may include a reduced amount of one or more (N-x) oligonucleotide products. Also provided are pharmaceutical compositions including the subject oligonucleotide compositions.
Patent MX-2021009469-A (MX)
Title: Enhanced crude oil recovery from subterranean crude oil-bearing sandstone reservoirs.
Inventor: KNIGHT TROY E
IPC: C09K8/584
Filed: 2020-02-17
Abstract: The present disclosure provides for a sandstone-containing oil reservoir additive composition that includes (a) a nonionic wettability alteration agent having Formula (I): and (b) an injection fluid. For Formula (I), R is an alkyl residue from a branched secondary alcohol initiator, where R can have a carbon number of C4 to C10, x is from 3 to 10 and y is from 1 to 20. The injection fluid can be selected from the group consisting of sea water, engineered water, injection brine, produced brine or combinations thereof. The nonionic wettability agent in the sandstone reservoir additive composition can be from 0.01 weight percent (wt%) to 20 wt% based on the total weight of the sandstone reservoir additive composition. The sandstone-containing oil reservoir additive composition can be used in enhance oil recovery operations, such as a waterflooding operation or a carbon dioxide flooding operation.
Patent MX-2021009996-A (MX)
Title: A container for holding and gravity-feed dispensing articles.
Inventor: GIANNOPOULOS PANAGIOTIS
IPC: B65D5/42
Filed: 2020-04-14
Abstract: A container (1) for holding and gravity-feed dispensing articles comprises a front panel (3), a back panel, an upper panel (2), a lower panel (6), and two side panels, the two side panels extending between the upper panel and the lower panel. The front panel, the back panel, the lower panel, and the two side panels form one or more voids for holding a stack of articles such as shavers. The front panel (3) includes a removable perforated portion (8a) on the bottom of the front panel that, when removed, defines a dispensing opening adapted for dispensing an article from the stack of articles, and the front panel, the back panel, the upper panel, the lower panel, and the two side panels are formed from exactly one die cut blank.
Patent MX-2021010163-A (MX)
Title: Method for grinding a hydraulic binder.
Inventor: OYTUN YAZAN HÜSEYIN
IPC: C04B28/02
Filed: 2020-02-25
Abstract: The application relates to a method for grinding a hydraulic binder comprising: a) introducing: - a hydraulic binder, and - a composition B comprising at least one grinding aid B, in the first chamber (12) of a horizontal grinder (11) comprising several chambers (12, 14), including a first chamber (12) and a last chamber (14), each chamber (12) being separated from the adjacent chamber (14) by a diaphragm (17), whereby a composition b comprising the hydraulic binder and the composition B is obtained in the first chamber (12), b) grinding the composition b in the horizontal grinder (11), whereby the composition b moves from the first chamber (12) to the last chamber (14) and a ground composition C is obtained at the outlet of the last chamber (14), characterised in that it comprises, during the grinding step, introducing, into the last chamber (14), a composition A comprising at least one grinding aid A comprising an amino alcohol, and the grinding unit intended for implementing same.
Patent MX-2021011484-A (MX)
Title: D-metyrosine compositions and methods for preparing same.
Inventor: ZUCARO JOHN
IPC: C07C227/18
Filed: 2020-03-18
Abstract: The disclosure provides processes for preparing a compound of formula I, comprising reacting a compound of formula II with an aqueous acid in a solvent and at a temperature sufficient for at least about 48 hours to produce a compound of formula I: wherein, R<sup>1</sup>-R<sup>5</sup> are defined herein. Also provided are D-metyrosine prepared according to the processes described herein and compositions comprising the D-metyrosine provided herein.
Patent MX-2021015427-A (MX)
Title: Processed microbial extracellular vesicles.
Inventor: GOODMAN BRIAN
IPC: A61K35/744
Filed: 2020-06-11
Abstract: Provided herein are methods and pharmaceutical compositions related to processed microbial extracellular vesicles (pmEVs) that can be useful as therapeutic agents.
Patent MX-2022001233-A (MX)
Title: Modelling of a fluid treatment system.
Inventor: CHEN CHENG
IPC: G06K15/02
Filed: 2022-01-28
Abstract: Embodiments of modelling a fluid treatment system are provided herein. One embodiment comprises obtaining synthetic data for a fluid treatment system from a data store. The fluid treatment system comprises a membrane and the fluid treatment system is configured to receive a stream of fluid for treatment. The embodiment comprises training a machine learning pressure prediction model using the synthetic data to predict a pressure for the membrane of the fluid treatment system. The trained pressure prediction model is combinable with an operator training simulator (OTS) model to update the OTS model to improve accuracy of simulation pressure output from the OTS model..
Patent MX-2022001321-A (MX)
Title: Anti-ctla4-anti-pd-1 bispecific antibody and uses thereof.
Inventor: ZHANG PENG
IPC: C07K16/46
Filed: 2020-07-31
Abstract: Provided are an anti-CTLA4-anti-PD-1 bispecific antibody and uses thereof. The bispecific antibody comprises: a first protein functional area targeting PD-1 and a second protein functional area targeting CTLA4, where, according to the EU numbering system, the constant region of an immunoglobulin heavy chain is mutated at any two loci or three loci of locus 234, locus 235, and locus 237, and after the mutation, the affinity constant of the bispecific antibody with FcÎ³RIIIa and/or C1q is reduced compared to that before the mutation. The bispecific antibody is capable of specifically binding with CTLA4 and PD-1, disabling the immunosuppression of CTLA4 and PD-1 with respect to the body, and activating T lymphocytes, and is applicable in preventing, treating, or diagnosing a tumor or anemia.
Patent MX-2022002447-A (MX)
Title: Compositions and methods for treatment of influenza a infection.
Inventor: MOGALIAN ERIK
IPC: A61K39/42
Filed: 2020-08-28
Abstract: The present disclosure provides antibodies, antibody compositions, and methods for use in prophylaxis and treatment of influenza A infection. In certain embodiments, a single administration of a presently disclosed antibody or antibody composition is useful to protect against and/or treat an influenza A infection for a full flu season.
Patent MX-2022008200-A (MX)
Title: Use of co values in smoking cessation.
Inventor: UTLEY DAVID S
IPC: A61B5/097
Filed: 2020-12-23
Abstract: Use of co values in smoking cessation are described where an apparatus may be configured to encourage smoking cessation in a user. The apparatus may include a sampling unit which receives a sample breath and determines a level of exhaled carbon monoxide from the sample breath. The sampling unit may be programmed to initiate a first timer for tracking a cumulative time upon a determination that the level of exhaled carbon monoxide is below a predetermined threshold. The sampling unit may also be programmed to initiate a second timer for tracking a countdown time upon a determination that the level of exhaled carbon monoxide is above the predetermined threshold, wherein the countdown time corresponds to a second length of time until the carbon monoxide level within the body of the user is expected to dissipate below the predetermined threshold.
Patent MX-2022008513-A (MX)
Title: Methods of treating cortical dementia associated wandering.
Inventor: JACOBSON SVEN
IPC: A61K31/407
Filed: 2021-01-08
Abstract: The invention is based on the discovery that rho kinase inhibitors can be used to treat certain dementia-associated wandering. The inventive methods relate to the use of rho kinase inhibitors in the treatment of patients with cortical dementia-associated wandering. Preferred aspects of the invention contemplate treating wandering due to cortical vascular dementia and wandering due to dementia where the patient is a persistent wanderer and/or where the patient does not display a wayfinding defect.
Patent MX-2022009266-A (MX)
Title: Transporting and storage container for liquids.
Inventor: GUTEWORT SVEN
IPC: B65D85/84
Filed: 2021-01-29
Abstract: The invention relates to a packaging unit for the transport and/or storage of at least one organic peroxide, which is designed to ensure improved storage and transport safety of organic peroxides.
Patent MX-2022009571-A (MX)
Title: Roofing membrane bond indicator.
Inventor: WANG RUIZHENG
IPC: C09D11/50
Filed: 2021-02-05
Abstract: A thermochromic indicator and its use for visually determining whether adjacent surfaces of overlapping edge portions of side-by-side roofing membrane segments have been sufficiently heated to a preselected temperature threshold to achieve a desired weld therebetween to correspondingly seal the roofing membrane seam.
Patent MX-2022010439-A (MX)
Title: Selective androgen receptor covalent antagonists (sarcas) and methods of use thereof.
Inventor: NARAYANAN RAMESH
IPC: A61K31/325
Filed: 2021-02-24
Abstract: This invention relates to selective androgen receptor covalent antagonists, synthetic intermediates and by-products, and related compounds, and compositions comprising the same, and uses thereof in treating androgen receptor dependent diseases and conditions such as hyperproliferations of the prostate including pre-malignancies and benign prostatic hyperplasia, prostate cancer, advanced prostate cancer, castration resistant prostate cancer, triple negative breast cancer, other cancers expressing the androgen receptor, androgenic alopecia or other hyperandrogenic dermal diseases, Kennedy's disease, amyotrophic lateral sclerosis (ALS), abdominal aortic aneurysm (AAA), and uterine fibroids, and to methods for reducing the levels of androgen receptor-full length (AR-FL) including pathogenic or resistance mutations, AR-splice variants (AR-SV), and pathogenic polyglutamine (polyQ) polymorphisms of AR.
Patent MX-2022011362-A (MX)
Title: Looped primer and loop-de-loop method for detecting target nucleic acid.
Inventor: BALL CAMERON SCOTT
IPC: C12N15/11
Filed: 2021-03-12
Abstract: The present disclosure provides a novel loop-de-loop method of detecting a target nucleic acid using a biosensor-labeled oligonucleotide. Further provided herein is a looped primer and a kit for use in the method.