baber/WOPTO huggingface dataset:
Patent CA-2244363-C (CA)
Inventor: HOLT DENNIS A
IPC: C07D405/12
Filed: 1997-02-28
Granted: 2006-11-14
Abstract: L'invention concerne de nouveaux composés de multimérisation d'immunophilines et des protéines contenant de l'immunophiline ou des domaines apparentés à l'immunophiline. Les composés ont la formule (I) M-L-Q, un de leur stéréoisomère résolu ou un mélange d'un ou de plusieurs de ces stéréoisomères, et leurs sels pharmaceutiquement acceptables, formule dans laquelle M représente un groupe de liaison d'immunophiline comprenant une fraction de la formule (II) dans laquelle G est choisi indépendamment dans le groupe constitué de (a, b, c), Q comprend une fraction de formule (II), un ligand FKBP macrocyclique naturel ou un dérivé de celui-ci, ou bien un ligand FKBP synthétique de formule (III) dans lesquelles n = 1 ou 2; X = O, NH ou CH2; B<1> and B<2> représentent indépendamment H ou aryle ou hétéroaryle aliphatique, hétéroaliphatique; Y = O, S, NH, -NH(C=O)-, -NH(C=O)-O, -NH(SO2)- ou NR<3>, ou il représente une liaison covalente de R<2> à l'atome de carbone 9, R<1>, R<2>, et R<3> sont identiques ou différents et représentent indépendamment aryle ou hétéroaryle aliphatique, hétéroaliphatique, et L représente une fraction de liaison liant de manière covalente des monomères M à Q ou liant de manière covalente M<1> à M<2> par des liaisons covalentes à soit R<1> soit R<2>, non nécessairement identiques dans chacun de M<1> et M<2>.
Patent CA-2249054-C (CA)
Title: Performance enhancing shoe components and methods
Inventor: CROW WILLIAM
IPC: A43B13/12
Filed: 1998-09-29
Granted: 2001-09-25
Abstract: The present invention provides performance enhancing shoe components. The invented shoe component includes an upper layer of 1,4-polybutadiene and, optionally, a rubber such as natural rubber, synthetic isoprene rubber or polyisoprene. The first layer is attached to a resilient layer which extends substantially the length of the shoe. Optionally, a third layer or a coating may be attached to the resilient layer. The invented shoe components may be formed as shoe inserts, insoles, midsoles or shoe soles.
Patent CA-2256221-C (CA)
Title: Method for adding context to communications
Inventor: BRISEBOIS MICHEL A
IPC: H04M3/533
Filed: 1998-12-16
Granted: 2004-05-11
Abstract: A method for augmenting communications between called and calling parties with context information helps either or both parties decide whether and how to accept or initiate a communications event.
Patent CA-2265622-C (CA)
Inventor: DEBERRY DAVID W
IPC: B01D53/52
Filed: 1997-09-08
Granted: 2002-11-12
Abstract: A process and system for removing hydrogen sulfide from a gaseous stream such as one of natural gas. A sour gas stream containing H2S is contacted with a nonaqueous, water-insoluble sorbing liquor which comprises an organic solvent for elemental sulfur, dissolved elemental sulfur, an organic base to promote the reactions, and an organic solubilizing agent, an agent suitable for maintaining the solubility of polysulfide intermediate which may otherwise separate when they are formed during operation of the process. Hydrogen sulfide (H2S) gas is sorbed into this liquor and then reacts with the dissolved sulfur in the presence of the base to form polysulfide molecules. The solution is then sent to a react or where sufficient residence time is provided to allow the polysulfide forming reactions to reach the desired degree of completion. Fro m the reactor, the solution flows to a regenerator where  the solution is oxidized (e.g., by contact with air), forming dissolved elementa l sulfur and water. The temperature of the solution is t hen lowered, forming sulfur crystals, which are easily removed by gravity settli ng, filtration, centrifuge, or other separation method. Enough sulfur remains dissolved in the solution following removal of the sulfur cry stals that when this solution is reheated and returned t othe absorber a sufficient amount of sulfur is present to react with the inlet H2 S gas.
Patent CA-2273473-C (CA)
Inventor: ST LOUIS ROBERT MAURICE
IPC: D06F58/26
Filed: 1999-05-27
Granted: 2004-11-02
Abstract: An electric clothes dryer has an irregular polygonal shaped rear wall where the apexes in the polygon align readily with the center of the heater housing to define positions where the electrical insulators are mounted to the heater housing rear wall. Raised land pads are formed from the rear wall of the heater housing at these locations and on which the insulators are mounted. The raised land pads further have radial slots that permit airflow from beneath the pad into the heater housing and across the insulator and the heating element. The apexes further provide an increased air gap for increased airflow radially across the electrical insulators. The heater housing has an air gap with the rear end head of the dryer drum which air gap is smaller adjacent the upper portions of the heater housing so as to reduce the chimney effect associated with the air heated in the heater housing.
Patent CA-2278626-C (CA)
Title: Novel method for the isolation of polysaccharides
Inventor: HASLER THOMAS
IPC: A61K39/102
Filed: 1998-01-20
Granted: 2010-04-27
Abstract: The invention relates to a method for the isolation of polysaccharides, in particular for the separation of endotoxins from capsule polysaccharides of gram-negative bacteria. The polysaccharides isolated by this method are preferably used for the production of polysaccharide vaccines. The invention furthermore relates to vaccines containing polysaccharides isolated by the method described in this invention.
Patent CA-2280398-C (CA)
Inventor: ZHANG KAI
IPC: H01L33/64
Filed: 1999-08-16
Granted: 2009-01-20
Abstract: Apparatus for exciting a fluorescent or phosphorescent molecule applied to a specimen in a microscope, the molecule having a known excitation wavelength, comprises a semiconductor light source capable of emitting an output light within a preselected wavelength band correlated with the excitation wavelength of the molecule, an electronic controller coupled to the light source for controlling the intensity of the output light, and an optical system for converting the output light into an excitation beam having a pre-selected distribution of light flux suitable for illuminating the specimen. The semiconductor light source is preferably a light emitting diode or superluminescent diode. The subject invention provides for a fluorescence excitation illuminator having a long lifetime and relatively low cost. Intensity modulation or attenuation can be achieved electronically, without the need for shutters.
Patent CA-2281318-C (CA)
Title: Safe class-2 motor control circuit and method adapted for electric vacuum cleaning system suction motor and agitator motor control
Inventor: BRESLIN JOHN J
IPC: H02P1/02
Filed: 1999-09-03
Granted: 2011-08-09
Abstract: A control circuit is disclosed for selectively energizing an electrical device, such as a central vacuum cleaning system motor, coupled to the control circuit via a pair of conductive wires with an operating voltage. The control circuit has a circuit for selectively supplying and withholding operating electrical power to the electrical device. A first current detector is connected to a control voltage and senses a current flow resulting from closure of a circuit connected to a control voltage in at least one wire of the pair of conductive wires. A second current detector connected to the operating voltage senses a current flow resulting from closure of a circuit connected to the operating voltage in at least one wire of the pair of conductive wires. A first switching device responsive to the first current detector disconnects the control voltage from at least one of the wires and connects the operating voltage to the conductive pair. A second switching device responsive to the second current detector maintains the operating voltage to the conductor pair. The second switching device is responsive to the second current detector to connect the operating power to the electrical device.
Patent CA-2281420-C (CA)
Title: Preparation of pharmaceutically-active granules
Inventor: WYNN DAVID W
IPC: A61K31/485
Filed: 1999-09-03
Granted: 2008-11-18
Abstract: The present invention provides a core of predominately microcrystalline cellulose, on which an active drug is layered onto the core via solution coating. The coated particles have a narrower particle size distribution than coated granules provided by other processes. An optional final coating of a pharmaceutically acceptable polymeric coating is provided to provide tastemaking or controlled release, and protection of the drug-layered particles.
Patent CA-2283835-C (CA)
Title: Contrasting gloss surface coverings and surface coverings optionally containing dispersed wear-resistant particles and methods of making the same
Inventor: SHULTZ JEFFREY R
IPC: B44F9/02
Filed: 1999-01-27
Granted: 2003-03-18
Abstract: A surface covering comprising at least one layer containing wear-resistant particles, such as aluminum oxide, is disclosed. Preferably, the wear-resistant particles are present in the outermost layer of the surface covering which is exposed to the environment. A method to improve wear and/or stain resistance to a surface covering is also disclosed and includes adding an effective amount of wear-resistant particles to a top coat layer or outermost layer of a surface covering optionally, with the use of a suspension aid.  Also, layers of surface coverings having differences in gloss levels are also disclosed. Methods of making the surface coverings are also disclosed.
Patent CA-2286183-C (CA)
Inventor: BUECHLER KENNETH F
IPC: G01N33/58
Filed: 1998-04-06
Granted: 2008-11-18
Abstract: Disclosed is a fluorescent conjugate comprising a biological reagent, a fluorescent molecule, and a means for impeding phototoxic degradation of the biological reagent. The impeding means can be a cross- linking substance having a long molecular distance, whereby the cross-linking substance links the fluorescent molecule and the biologica l reagent; a quencher of singlet oxygen; a quencher of a free radical; or a combination thereof. Also disclosed is a solution comprising a fluorescent conjugate of a biological reagent and a fluorescent molecule together with an oxygen depleting system.
Patent CA-2290635-C (CA)
Inventor: JOHNSTON MARK H
IPC: A61B19/02
Filed: 1998-04-15
Granted: 2009-12-15
Abstract: L'invention concerne un procédé et un appareil de traitement des tissus de Barrett, un état pré-cancéreux en enlevant par cryo-ablation l'épithélium se trouvant au-dessus du sphincter oesophagien inférieur. On utilise un endoscope (10) avec fibre optique pour visionner l'opération et on fait passer au travers du canal intérieur de l'endoscope un cathéter (20) d'alimentation en azote liquide (LG). L'azote liquide est atomisé directement sur les tissus de Barrett par l'intermédiaire du cathéter pendant que le chirurgien visionne l'opération à l'aide de la fibre optique de l'endoscope et peut contrôler l'atomisation par l'intermédiaire d'une soupape. La blancheur est une indication de congélation et signifie que l'épithélium a été enlevé par cryo-ablation. L'appareil peut également être utilisé pour d'autres lésions du tractus gastro-intestinal. La caractéristique la plus importante et significative de cette invention réside dans le fait que l'azote liquide est atomisé à basse pression dans l'oesophage.
Patent CA-2292278-C (CA)
Inventor: KAISER TRENT
IPC: E21B43/12
Filed: 1999-12-10
Granted: 2005-06-21
Abstract: A method of achieving a preferential flow distribution in a horizontal well bore. This method consists of the step of positioning in a horizontal wellbore a slotted liner having a plurality of slots which provide a flow area. The slot open flow area of the slotted liner varying along its length in accordance with a selected strategy of flow distribution. The preferred strategy being to create an overbalanced condition in the wellbore which promotes promote a higher flow at the toe portion than at the heel portion.
Patent CA-2292373-C (CA)
Inventor: MCCONNELL JEFF C
IPC: B65B25/06
Filed: 1999-12-17
Granted: 2004-04-20
Abstract: A packaging method and apparatus perform the steps of:   a. providing a film including a first film component peelably adhered to a second film component;   b. providing a support member for supporting a product thereon;   c. forming a seal between the second film component and the support member, the seal extending around the product to define a sealed enclosure for the product between the film and the support member;   d. separating the first film component from the second film component within a predetermined region of the film located outside of the sealed enclosure; and e. severing the film within the predetermined, separated region to form an edge on the first film component within the separated region; thereby providing a tab for peeling the first film component from the second film component.
Patent CA-2294825-C (CA)
Inventor: SIEGLER JEAN-PIERRE
IPC: C06B45/00
Filed: 1998-06-16
Granted: 2003-08-12
Abstract: The invention concerns a pyrotechnic projectile comprising a body containing a bursting charge (4) and a combustible charge (5) which is ignited and dispersed by the bursting charge (4), characterised in that the combustible charge (5) is formed by a metallic powder combustible with oxygen, arranged in the bursting charge (4) according to a pattern corresponding of the flare pattern to be obtained in the sky. The metallic powder can be titanium, aluminum or magnesium powder.
Patent CA-2295009-C (CA)
Inventor: SUZUKI YUUJI
IPC: A61H23/04
Filed: 1999-04-27
Granted: 2004-01-06
Abstract: A positioning device, wherein pneumatically telescopable telescoping bodies (23, 24, 146) are disposed on both sides of reciprocatingly movable members (22, 144) in the moving direction, and valve devices (45, 46, 163, 164) for holding the telescoping bodies in any extended state by a valve closing operation are installed on air route devices (32, 37, 148, 149) for supplyin g air from air supply devices (25, 160) to the telescoping bodies. A massaging machine having the positioning device, wherein the movable members are movab ly vertically guided by guide members (44, 28, 141) installed on back rest part s (4, 104) of chair main bodies (1, 102), treating elements (16, 130) which project from the surface of the back rest parts and in contact with a human body seated on the chair main bodies are installed on the movable members, a nd the movable members are moved by the supply and exhaust of air from the air supply devices through the air route devices to the telescoping bodies locat ed on both sides of the movable members in the movable direction so as to adjus t the moving position by the valve devices installed on the air route devices.
Patent CA-2296733-C (CA)
Inventor: LEE DONG-HUN
IPC: C12Q/
Filed: 1998-06-18
Granted: 2011-08-16
Abstract: Cette invention a trait à une technique de purification d'ARN viral provenant d'un prélèvement biologique. Cette technique consiste à provoquer la lyse d'une enveloppe virale pour libérer l'ARN et à faire passer le lysat par un filtre en poly(fluorure de vinylidène) (PVDF) hydrophile et poreux pour capturer l'ARN viral. Le filtre sur lequel l'ARN s'est fixé est ensuite lavé pour en enlever les protéines, les lipides et d'autres substances contaminantes. L'ARN est extraite du filtre par utilisation d'une solution exempte de ribonucléase (Rnase) à faible force ionique afin d'obtenir une solution contenant de l'ARN viral purifié. On récupère ensuite l'ARN dans cette solution. La technique selon cette invention se prête également à la purification d'acides nucléiques provenant d'autres types d'échantillons.
Patent CA-2303594-C (CA)
Title: Compounds for treating and preventing diabetic complications
Inventor: MYLARI BANAVARA LAKSHMAN
IPC: A61P9/10
Filed: 2000-03-30
Granted: 2004-07-06
Abstract: This invention is directed to sorbitol dehydrogenase inhibitory compounds of the formula I, (see formula I) wherein R is as defined in the specification. This invention is also directed to pharmaceutical compositions containing those compounds and methods of treating or preventing diabetic complications, particularly diabetic neuropathy, diabetic nephropathy and diabetic cardiomyopathy by administering such compounds to a mammal suffering from diabetes and therefore at risk for developing such complications. This invention is also directed to pharmaceutical compositions comprising a combination of a compound of formula I of this invention with an aldose reductase inhibitor and to methods of treating or preventing diabetic complications therewith. This invention is also directed to pharmaceutical compositions comprising a combination of a compound of formula I of this invention with an NHE-1 inhibitor and to methods of treating cardiomyopathy and other heart-related problems therewith. This invention is also directed to certain intermediates used in the synthesis of the compounds of formula I and to processes for preparing those intermediates.
Patent CA-2310511-C (CA)
Inventor: WU CHEN H
IPC: F21V17/00
Filed: 2000-06-02
Granted: 2007-07-31
Abstract: A method and apparatus for retro-fitting a traffic signal lamp with an LED lamp module. The traffic signal lamp has a housing, a front door plate attached to the housing, a lens attached to the front door plate, a reflector in the housing, a threaded electrical socket connector in the housing, and a threaded light bulb connected into the socket connector. The LED lamp includes plurality of light emitting diodes, a power supply electrically connected to the plurality of light emitting diodes, and wires extending from the power supply that terminate in a threaded electrical connector compatible with the socket connector. The method of the present invention includes removing the lens from the front door plate, removing the threaded light bulb from the socket connector, affixing an LED lamp module to the front door plate, and connecting the threaded electrical connector of the LED lamp module to the socket connector.
Patent CA-2316739-C (CA)
Title: Preparation of cells for production of biologicals
Inventor: BRANDS RUDI
IPC: C12N5/071
Filed: 1998-12-17
Granted: 2011-06-21
Abstract: The present invention relates to a method for the preparation of cells for use in the production of biologicals, by culturing cells up till a desired cell volume of a preproduction batch, where after in a repeated discontinous process: a) part of the cells of the preproduction batch is used for the preparation of at least one production batch, and b) the remaining part of the cells of the preproduction batch is used as a seed for the preparation of at least one subsequent preproduction batch.
Patent CA-2322924-C (CA)
Title: Gas turbine equipment and turbine blade
Inventor: WATANABE KOJI
IPC: F01D5/30
Filed: 2000-10-10
Granted: 2004-12-28
Abstract: The turbine blade of a gas turbine and gas turbine equipment using the turbine blade, as disclosed, suppresses the occurrence of thermal stress caused by a difference in temperature thereby providing a highly reliable gas turbine blade and gas turbine equipment. The gas turbine equipment of the present invention comprises a rotational portion of a rotor (1), a moving blade (2), a stationary portion of casing (3), a stationary blade (4), various supporting members and a combustor. A thermal stress reducing portion is provided in one or both of the moving blade joint adjacent portion (14a), between the moving blade trailing edge portion (14) and the platform (15), and the stationary blade joint adjacent portion (20a), between the stationary blade trailing edge portion (20) and the shroud (18, 19). The thermal stress reducing portion, as disclosed, reduces undesirable thermal stress occurring in the blade joint adjacent portions (14a, 20a), and reliability of the turbine blade and gas turbine equipment is enhanced.
Patent CA-2326208-C (CA)
Inventor: MIZUTANI KATSUMI
IPC: A61F13/56
Filed: 2000-11-17
Granted: 2006-11-28
Abstract: A disposable absorbent sanitary article includes sheets to form a pair of barrier flaps and side flaps, each of which are folded along flap fold lines back onto themselves, respectively, to form free edge portions of the respective pairs of flaps. Elastic members secured under tension to the sheets inside the respective free edge portions are spaced from the fold lines at least by 1 mm, respectively.
Patent CA-2326677-C (CA)
Inventor: WOOD R ANDREW
IPC: G01J1/02
Filed: 1999-03-30
Granted: 2008-06-10
Abstract: A method for fabricating a wafer-pair having at least one recess in one wafer and the recess formed into a chamber with the attaching of the other wafer which has a port plugged with a deposited layer on its external surface. The deposition of the layer may be performed in a very low pressure environment, thus assuring the same kind of environment in the sealed chamber. The chamber may enclose at least one device such as a thermoelectric sensor, bolometer, emitter or other kind of device. The wafer-pair typically will have numerous chambers, with devices, respectively, and may be divided into a multiplicity of chips.
Patent CA-2326684-C (CA)
Inventor: CAI WEI WEN
IPC: C12Q1/6837
Filed: 1999-05-04
Granted: 2006-03-14
Abstract: L'invention concerne de nouveaux acides nucléiques modifiés chimiquement présentant une labilité améliorée pour des supports solides, tels que le verre. Ces acides nucléiques modifiés se fixent aisément à des supports solides, tels qu'une surface de verre, sans dérivatisation préalable de ladite surface. L'invention concerne en outre des micro-réseaux haute densité obtenus à partir desdits acides nucléiques ainsi que des procédés de préparation desdits micro-réseaux.
Patent CA-2327307-C (CA)
Inventor: SHERMAN ADAM
IPC: B65D81/32
Filed: 2000-02-16
Granted: 2005-09-06
Abstract: A dispensing nozzle (1) for a container (2) having at least two separate compartments (4, 5) and a single neck finish. The dispensing nozzle comprises a hollow shell (6) having an outer surface, an inner surface, a distal end, and a proximal end. At least one partition (11) projects inwardly from the inner surface of the shell, the partitions defining at least two channels (12, 13) within the shell, each channel aligning with a separate compartment of the container. A flange (14) extends radially from the outer surface of the shell, the flange having an upper surface and a lower surface, the lower surface seating against the sealing surface of the container neck. The proximal end (20) of the shell extends beyond the flange and is configured so as to conform to the dimensions of the inner surface of the container neck.
Patent CA-2327935-C (CA)
Title: System and method to provide real time transaction validation and billing via a communications network
Inventor: COOPER DAVE M L
IPC: G06F17/30
Filed: 2000-12-08
Granted: 2013-10-22
Abstract: A system and method for providing real-time validation to a content provider of a customer's request transmitted via a communications system for delivery of content by the content provider to the customer via the communications system. A request for validation of the customer from the content provider, the request including data identifying the customer, is dealt with by determining from the identifying data whether the customer is a subscriber and then immediately requesting acknowledgment by the customer of the customer's request for the delivery of the content. Upon receipt of an acknowledgment from the customer a validation of the customer's request is sent to the content provider.