baber/WOPTO huggingface dataset:
Patent CA-2779070-C (CA)
Title: New therapeutic approaches for treating alzheimer disease
Inventor: COHEN DANIEL
IPC: A61K31/195
Filed: 2010-10-29
Granted: 2020-02-25
Abstract: The present invention relates to compositions and methods for the treatment of Alzheimer's disease and related disorders. More specifically, the present invention relates to novel combinatorial therapies of Alzheimer's disease and related disorders. In particular, the invention concerns compounds which, alone or in combination(s), can effectively modulate synapse function and/or angiogenesis and/or cell stress response. The invention also relates to methods of producing a drug or a drug combination for treating Alzheimer's disease and to methods of treating Alzheimer's disease or a related disorder.
Patent CA-2779441-C (CA)
Title: Tremie de vis sans fin avec capacite de retenue de trop-plein amelioree
Inventor: PUTMAN KEITH
IPC: A01D90/10
Filed: 2012-06-05
Granted: 2014-08-19
Abstract: Une fixation de trémie de vis sans fin peut être positionnée immédiatement adjacente à une sortie de trémie à grains pour réduire la perte de grains lors d'un transfert. La trémie comprend un support réglable qui peut être utilisé pour régler la position verticale de la trémie et la soulever vers la sortie de la trémie à grains.
Patent CA-2780788-C (CA)
Inventor: WU MINGLIANG
IPC: H05B37/02
Filed: 2012-06-15
Granted: 2015-03-17
Abstract: An illustrative LED driver circuit includes an automatic on and off control function using a light sensing circuit having a light sensing element reacting to ambient light. The circuit uses flyback converter topology and a power factor correction (PFC) controller. The light sensing function is provided by coupling the light sensing circuit to a monitoring/disable function of the PFC controller, thus providing automatic on and off control of the LED driver circuit by using a light sensing element such as a photocell.
Patent CA-2787849-C (CA)
Inventor: WEISS ANTHONY STEVEN
IPC: C07K14/78
Filed: 2010-03-10
Granted: 2018-03-06
Abstract: La présente invention concerne des compositions de biomatériau injectable formées à partir de tropoélastine pour la réparation et la restauration de tissu. Les compositions comprennent un agent de contrôle de coalescence sous la forme d'un polysaccharide ou un dérivé de polysaccharide, en une quantité efficace pour produire la substance avec les propriétés d'écoulement, permettant l'injection.
Patent CA-2788102-C (CA)
Inventor: REDEKOPP DANIEL T
IPC: B42D1/02
Filed: 2012-08-20
Granted: 2018-08-14
Abstract: The invention is an improved paperclip consisting of a wire clip, with a plurality of loops and a guiding mat attached to one or more of the loops to form a gripping receptacle. The invention is further improved by attaching a mounting device on the flip side of the gripping receptacle. The mounting device secures the clip to a stationary surface and prevents the clip from moving when an article is inserted into the gripping receptacle. Once the article is bound by the clip, the clip and article may then be mounted to a suitable surface for display or storage.
Patent CA-2792021-C (CA)
Title: Fused disconnect switch with terminal opening cover
Inventor: SU JIEHUA
IPC: H01H21/16
Filed: 2011-01-31
Granted: 2018-02-13
Abstract: A fusible switching disconnect device includes a switch housing (52) and terminal cover (90) therefore that blocks access to a line side fuse clip (60) and prevents insertion of a rectangular fuse module (54) when switch contacts (74,76) in the device are closed. An interlock element (92) further presents th fuse from being retracted when the switch contacts are closed.
Patent CA-2794943-C (CA)
Inventor: SWANDA ANTHONY P
IPC: C12M1/34
Filed: 2011-03-03
Granted: 2015-01-06
Abstract: The present invention provides methods of multiplying plant embryogenic tissue in a bioreactor. The method of multiplying plant embryogenic tissue in a bioreactor specifically comprisies the steps of: (a) inoculating plant embryogenic tissue and multiplication media into a bioreactor; (b) measuring a parameter that is a direct measure of, or correlated to, a concentration of the plant embryogenic tissue in the bioreactor; (c) using the measurement obtained in step (b) to calculate a flow rate of additional multiplication media; (d) delivering additional multiplication media to the bioreactor based on the flow rate calculated in step (c); and (e) periodically repeating steps (b) to (d).
Patent CA-2798191-C (CA)
Title: Dispositif de distribution de produit
Inventor: KOENIGSKNECHT TONY L
IPC: A47F10/02
Filed: 2011-05-04
Granted: 2015-04-07
Abstract: L'invention porte sur un système, sur un dispositif et sur un procédé pour la distribution d'un produit, lequel dispositif comprend un système de distribution qui comprend au moins une vis sans fin ayant une hélice interne qui est soit d'un seul tenant avec une paroi interne d'une partie corps de la vis sans fin, soit fixée à celle-ci. La vis sans fin tourne et l'hélice dans la vis sans fin transmet un produit d'une station de chargement en vrac à une zone de distribution de produit. Ainsi, les produits peuvent être chargés en vrac dans un dispositif plutôt que d'être chargés un par un dans un dispositif de distribution. L'hélice réduit les points de pincement associés aux systèmes de vis sans fin classiques.
Patent CA-2801301-C (CA)
Inventor: ETTER STEFAN
IPC: A47J31/56
Filed: 2011-06-14
Granted: 2018-07-31
Abstract: L'invention porte sur une unité (1000) destinée à commander la transmission d'énergie à un dispositif de conditionnement thermique (100), par exemple pour une machine à café, laquelle unité comprend une unité de commande (2) présentant un profil de démarrage pour le démarrage dudit dispositif (100), d'une température d'inactivité (TI) à une température de fonctionnement pour porter à une température cible (TT) un fluide qui circule à travers ledit dispositif (100) à la fin du démarrage, ladite unité de commande (2) étant disposée pour permettre une circulation de fluide à travers ledit dispositif (100) à la fin du démarrage et pour comparer la température déterminée (SOT) du fluide mis en circulation à la fin du démarrage à la température cible (TT) et en déduire une différence de température. L'unité est caractérisée en ce que le profil de démarrage a au moins un paramètre et en ce que ladite unité de commande (2) a un mode de d'auto-apprentissage pour ajuster ledit paramètre en fonction de ladite différence de température, et pour mémoriser le paramètre ajusté pour un démarrage ultérieur dudit dispositif (100). L'invention concerne en particulier un procédé pour obtenir un chauffage optimisé d'une machine à café (104).
Patent CA-2803150-C (CA)
Inventor: SASHI KAZUMICHI
IPC: C22C38/00
Filed: 2011-07-21
Granted: 2016-07-05
Abstract: In a semi-organic insulation coating comprising an inorganic component and an organic resin, a Zr compound and an Si compound containing a plate-like silica as an inorganic component are included in a ratio in a dry coating of 20 to 70 mass%  of Zr compound (converted to ZrO2) and 10 to 50 mass% of Si compound containing plate-like silica (converted to SiO2), and the remainder is substantially an organic resin, whereby there can be provided a magnetic steel sheet with a semi-organic insulation coating having no deterioration of corrosion resistance and water resistance without containing a chromium compound and being excellent in the powdering resistance, scratch resistance, sticking resistance, TIG weldability and punchability but also the coating appearance.
Patent CA-2804158-C (CA)
Inventor: ZHMUD BORIS
IPC: C23C26/00
Filed: 2010-07-16
Granted: 2017-10-10
Abstract: La présente invention se rapporte à un procédé de fabrication permettant d'obtenir une surface à faible coefficient de frottement. Ledit procédé consiste à utiliser (210) un élément mécanique. Un outil est frotté mécaniquement (212) contre une surface de l'élément mécanique. Un liquide de traitement est utilisé (214) sur une surface de contact entre l'élément mécanique et l'outil. Le liquide de traitement comprend un premier élément qui est un métal réfractaire, et un second élément qui est un chalcogène. Les premier et second éléments sont introduits dans une substance liquide. Le frottement mécanique est effectué avec une pression de contact qui est comprise entre 1 % et 100 % d'une résistance à la rupture de l'élément mécanique. De ce fait, le frottement mécanique provoque un polissage combiné de la surface de l'élément mécanique et un dépôt d'un tribofilm sur la surface de l'élément mécanique. Le tribofilm comprend le premier élément et le second élément.
Patent CA-2808418-C (CA)
Inventor: MCCAULEY SCOTT ALAN
IPC: A61K39/395
Filed: 2011-08-26
Granted: 2019-02-05
Abstract: The present disclosure provides compositions and methods of use involving binding proteins, e.g., antibodies and antigen-binding fragments thereof, that bind to the matrix metalloproteinase-9 (MMP9) protein (MMP9 is also known as gelatinase-B), wherein the binding proteins comprise an immunoglobulin (Ig) heavy chain (or functional fragment thereof) and an Ig light chain (or functional fragment thereof).
Patent CA-2808835-C (CA)
Title: Densitometre a vibration comprenant un element vibrant ameliore
Inventor: VAN CLEVE CRAIG BRAINERD
IPC: G01N9/00
Filed: 2010-11-05
Granted: 2017-02-14
Abstract: L'invention porte sur un appareil, qui comprend un élément vibrant (402). L'élément vibrant (402) est destiné à un densitomètre à vibration (400). L'élément vibrant (402) comprend une ou plusieurs ouvertures (420). La ou les ouvertures (420) sont dimensionnées et disposées dans l'élément vibrant (402) de façon à augmenter une séparation de fréquence entre une fréquence de résonance d'un mode de commande vibratoire souhaité et une fréquence de résonance d'un ou plusieurs modes vibratoires non souhaités.
Patent CA-2812186-C (CA)
Title: Elimination d'eau a partir de ldhis anti-agglomerant
Inventor: DURHAM DANNY
IPC: C09F9/00
Filed: 2011-09-21
Granted: 2017-10-10
Abstract: L'invention concerne un procédé de lutte contre de la corrosion dans un pipeline sous marin qui comprend l'apport d'un courant inhibiteur à faible dose (LDHI) composé d'une amine quaternaire et le séchage par un agent déshydratant.
Patent CA-2813776-C (CA)
Inventor: BECKMAN BLAKE
IPC: B60F5/00
Filed: 2013-04-15
Granted: 2020-09-01
Abstract: A hydraulic power system for a utility vehicle having an engine with a crankshaft. The system features first and second rotationally-driven power generating devices, one of which is a hydraulic pump and the other of which is an alternator and one of which is a hydraulic pump. The first device has a first rotational input for operative coupling to the crankshaft for driven rotation thereby. A connecting shaft has an input end portion arranged for rotational coupling to a rotationally driven member of the first device and an output end portion arranged for rotational coupling to a second rotational input of the second device for driving thereof under driven operation of the first rotationally-driven power generating device by the crankshaft. Higher power output of increased reliability is provided over prior art add-on hydraulic solutions using electric-over-hydraulic power packs.
Patent CA-2815165-C (CA)
Title: Embrayage a cannelure faciale
Inventor: RASZKOWSKI JAMES A
IPC: F16H57/02
Filed: 2011-10-18
Granted: 2018-06-26
Abstract: La présente invention se rapporte à un ensemble de changement de mode d'une transmission qui comprend un premier côté couplé à une entrée de rotation, un second côté couplé à une sortie de rotation et un actionneur. L'actionneur agit sur le premier côté pour déplacer le premier côté entre une première position dans laquelle les première et seconde surfaces de mise en prise sont désolidarisées, et une seconde position. Dans la première position, la rotation entre les premier et second côtés est indépendante. Dans la seconde position, les première et seconde surfaces de mise en prise sont mises en prise de telle sorte que la rotation soit transférée du premier côté au second côté.
Patent CA-2815400-C (CA)
Inventor: THOMSEN HENRIK
IPC: G01N33/14
Filed: 2010-11-30
Granted: 2017-10-24
Abstract: A system for the measurement of free and bound SO2 in a liquid beverage product sample comprising a sample container (10) having a volume sufficient to provide a headspace (14) above the sample (12) into which a gas can pass; a gas flow system (6) adapted to extract gas from the headspace (14) and recirculating it back into the liquid volume (12); a measurement system (4) configured to monitor a time dependent evolution of SO2 in gas from the gas flow system (6); and a dosing apparatus (8) fluidly connected to the container (10) to supply an hydrolysis reagent thereto. A heater unit (3) is provided for supplying thermal radiation into the container (10) to elevate the temperature of sample therein sufficient to facilitate the hydrolysis reaction and a signal processor (30) operates to deconvolute the monitored evolution to generate an indication of the concentration of each of the free SO2 and the total SO2 content of the sample.
Patent CA-2819875-C (CA)
Inventor: KELLUM WILBUR JAMES III
IPC: E05D15/00
Filed: 2013-06-28
Granted: 2017-03-21
Abstract: A window balance assembly comprising an improved locking carrier mechanism is disclosed. The locking mechanism is actuated when the window sash is tilted. Cam surfaces on the receiver of the mechanism engage cam followers in the clamshell-type housing of the carrier forcing them apart outwardly to lock the carrier in the jamb channel of a window assembly and prevent movement of the carrier in the channel. The receiver incorporates two cams that engage two cam follower surfaces in the housing to improve the distribution of the locking forces of the carrier in the jamb channel. A dual-locking carrier expands in both the axial and lateral directions to contact both front and back surfaces and opposing side surfaces of the jamb channel.
Patent CA-2819967-C (CA)
Inventor: BRADFORD WILLIAMSON ZIEGLER
IPC: A61K31/4418
Filed: 2013-07-04
Granted: 2016-03-22
Abstract: The disclosure relates to improved methods and use of pirfenidone therapy when ciprofloxacin is administered concomitantly, such as use of a reduced dose of pirfenidone with a 750 mg twice daily dose of ciprofloxacin.
Patent CA-2825102-C (CA)
Inventor: ASPNES GARY ERIK
IPC: C07D231/14
Filed: 2012-01-25
Granted: 2016-03-08
Abstract: The present invention provides a compound of Formula (I) or a pharmaceutically acceptable salt thereof wherein R1, R2, R3, A1, A2, A3, A4, L, B1, B2, B3 and B4 are as defined herein. The compounds of Formula I have been found to act as glucagon antagonists or inverse agonists. Consequently, the compounds of Formula I and the pharmaceutical compositions thereof are useful for the treatment of diseases, disorders, or conditions mediated by glucagon.
Patent CA-2825113-C (CA)
Inventor: IWABUCHI SHIGAKU
IPC: G06Q30/00
Filed: 2011-06-13
Granted: 2015-01-27
Abstract: This online shopping server (10) is provided with: a reception unit (17a) that, in the case that a plurality of first product information sets have been selected by user operations in a user terminal (T), acquires the selected plurality of first product information sets; a search unit (17b) that certifies common product attributes among the acquired plurality of first product information sets, and reads product information that differs from the plurality of first product information sets and that corresponds to the common product attributes as second product information; and a transmission unit (17c) that outputs the second product information in order for the read second product information to be displayed at the user terminal (T) along with the common product attributes.
Patent CA-2825655-C (CA)
Inventor: CAPE SAMUEL M
IPC: B42D25/45
Filed: 2012-01-27
Granted: 2019-04-30
Abstract: An optical device projecting one or more synthetically magnified images that has been laser marked with one or more static two dimensional (2D) images is provided. The static 2D image(s) laser marked on or within this device and the synthetically magnified image(s) projected by this device help determine the authenticity of a document (e.g., passport data page) or product that employs it. Several embodiments of the inventive device also offer increased resistance to tampering or alteration and wear.
Patent CA-2832896-C (CA)
Title: Devices and methods for securing tissue
Inventor: NODA WAYNE A
IPC: A61B17/122
Filed: 2012-05-29
Granted: 2015-12-29
Abstract: A compression ring (10, 34, 52, 70, 100) to grip and compress body structure such as diverticulum, hemorrhoids, and tissue adjacent a hole. A resilient ring shaped body (12, 36, 54, 72, 102) defines a compression channel (14, 38, 56, 74, 104), and an elongated axially rigid gripping member (16, 40, 58, 76, 106) extends diametrically across the through-opening. The gripping member (106) can rest on a flange (108) on the opposite side of the through-opening or engage with a second gripping member (42, 60, 78) that extends diametrically across the through-opening from the opposite side of the ring. Or, a flexible cage structure (124) can be disposed in the through-opening.
Patent CA-2833354-C (CA)
Title: Mems device and method for delivery of therapeutic agents
Inventor: MENG ELLIS
IPC: A61F9/00
Filed: 2007-03-14
Granted: 2015-12-15
Abstract: Embodiments of an implantable device for delivering a therapeutic agent to a patient include a reservoir configured to contain a liquid comprising the therapeutic agent and a cannula in fluid communication with the reservoir. The device and related methods may provide such features as constant-flow operation, an electrolytic mode of pumping, and/or wireless communication.
Patent CA-2837247-C (CA)
Inventor: GRIFFIOEN GERARD
IPC: C07D417/04
Filed: 2012-06-29
Granted: 2020-03-31
Abstract: The present invention relates to a compound of formula (IA) The present invention also relates to the use of the compound of formula IA for treating certain neurodegenerative disorders characterized by cytotoxic TAU misfolding and/or aggregation.
Patent CA-2842321-C (CA)
Inventor: INGBER DONALD E
IPC: A61K38/16
Filed: 2012-07-18
Granted: 2022-05-03
Abstract: Described herein are engineered microbe-targeting or microbe-binding molecules, kits comprising the same and uses thereof. Some particular embodiments of the microbe-targeting or microbe-binding molecules comprise a carbohydrate recognition domain of mannose-binding lectin, or a fragment thereof, linked to a portion of a Fc region. In some embodiments, the microbe-targeting molecules or microbe-binding molecules can be conjugated to a substrate, e.g., a magnetic microbead, forming a microbe-targeting substrate (e.g., a microbe-targeting magnetic microbead). Such microbe-targeting molecules and/or substrates and the kits comprising the same can bind and/or capture of a microbe and/or microbial matter thereof, and can thus be used in various applications, e.g., diagnosis and/or treatment of an infection caused by microbes such as sepsis in a subject or any environmental surface. Microbe-targeting molecules and/or substrates can be regenerated after use by washing with a low pH buffer or buffer in which calcium is insoluble.
Patent CA-2844157-C (CA)
Inventor: WEBB CHRISTOPHER J
IPC: A47L15/44
Filed: 2006-04-14
Granted: 2018-03-06
Abstract: A metering and dispensing closure for a container wherein two rotatable disks rotate in conjunction with a stationary cap member to afford accurate measuring of a powder material and dispensing of it. The disks and the container cap afford a consistent measuring of the powder material, as well as provide a variety of drive members which can be utilized with the dispensing closure.
Patent CA-2844608-C (CA)
Inventor: ANDERSSON PETER
IPC: B65D5/72
Filed: 2011-08-19
Granted: 2018-06-12
Abstract: A package for containing loose items comprising an inner casing accommodated slidably within an outer casing and capable of motion between a closed configuration, in which an opening presented by the inner casing is concealed by the outer casing, and an open configuration in which the opening is exposed. An appendage is hinged along a first line to a side wall of the outer casing, and along a second line to a side wall of the inner casing breasted in sliding contact with the side wall of the outer casing. The outer casing comprises a locking part with a flap folded to act against a locking part of the inner casing also comprising a flap. Said part of the outer casing is thicker than said part of the inner casing. The two locking parts prevent immediate opening of the package from the closed configuration to the open configuration.
Patent CA-2847138-C (CA)
Inventor: HERRINGTON W BENJAMIN
IPC: H04N21/454
Filed: 1999-11-30
Granted: 2016-09-13
Abstract: A system for searching for programs is provided. The system may be provide the user with an opportunity to indicate an interest in a given program. The system may provide the user with an opportunity to request that the system locate programs that are related to the given program in which the user has indicated an interest. The system may locate program listings that are related to the given program. The located program listings may be related to the given program based on attributes of the given program. The system may display a list of located listings and allow the user to select listings from the list. The system may tune to a program selected from the list, may display an information display screen for a program selected from the list, etc. The system may provide the user with an opportunity to configure and save search parameters. The system may sort related program listings based on the attributes of the given program. The system may provide the user with the opportunity to retrieve saved searches to locate currently available program listings and the opportunity to delete a saved search, rename a saved search, receive automatic notifications of programs matching a saved search, etc.
Patent CA-2848364-C (CA)
Title: Method for assembling a structure known as a box structure and structure obtained by such a method
Inventor: BAILLY DOMINIQUE
IPC: B64C3/26
Filed: 2012-09-17
Granted: 2020-02-25
Abstract: The invention relates to a method for assembling a skin (102) and the flange of a stiffener, characterized in that it involves the steps consisting in: a. sealing the periphery of the contact between the skin and the flange of the stiffener by applying a bead (210, 211) of adhesive to the flange of the stiffener in contact with the skin; b. creating a first and a second orifice, known as vent orifices, in the skin, said orifices opening at the interface between the skin and the flange of the stiffener; c. injecting adhesive through the first orifice termed the injection orifice at the interface between the skin and the flange of the stiffener while keeping said skin in contact with the stiffener until adhesive has fully filled the interface between the skin and the stiffener.