baber/WOPTO huggingface dataset:
Patent CA-2526893-C (CA)
Title: Inhibition of the expression of huntingtin gene
Inventor: KANAZAWA ICHIRO
IPC: A61P25/14
Filed: 2004-04-30
Granted: 2010-10-26
Abstract: It is intended to provide methods for suppressing the huntingtin gene expression by using a double-stranded RNA  (dsRNA), huntingtin gene expression inhibitors to suppress the huntingtin gene expression, and preventives and/or remedies of Huntington's disease. Targeting against a specific sequence of mRNA at immediately upstream of CAG repeats in HD genes of Huntington's disease, the huntingtin gene expression is suppressed by using a dsRNA homologous to the sequence. In this invention, a short siRNA (short double-stranded RNA) having bp as short as around 21-23 bp can be effectively used as the dsRNA  homologous to a specific RNA sequence in a region at immediately upstream of CAG repeats. The dsRNA of this present invention can be used as a huntingtin gene expression inhibitor, or a preventive and/or a remedy of Huntington's disease by administering or introducing into a living body or a living cell in mammals for the prevention and/or treatment of Huntington's disease.
Patent CA-2530030-C (CA)
Inventor: OYADOMARI RANDY
IPC: G06F15/16
Filed: 2004-06-30
Granted: 2011-02-08
Abstract: Protocol analyzers systems and methods coordinate the capture of network data of interest across multiple chassis. Each chassis has individual blades with accompanying ports and is serially connected to other chassis in the system.  Selected ports from each chassis are configured in domains that can be spread across the serially connected chassis and used in coordination to capture network data of interest. A serial protocol containing control signals is used to transmit run, stop, and trigger data between the serially connected chassis and thereby coordinate the activity of ports within each domain. Through the use of the serial protocol the number of wires connecting adjacent chassis is minimized and each of the blades in the multi~chassis systems can be synchronously started, stopped, and triggered at the same time to synchronously capture the network data of interest.
Patent CA-2531990-C (CA)
Inventor: KAROGAL NIKHIL
IPC: B23K9/173
Filed: 2006-01-04
Granted: 2013-12-03
Abstract: A flux cored, gas shielded arc welding electrode for depositing a weld metal with low diffusible hydrogen and having tensile strength greater than 90 Kpsi and a yield strength greater than 80 Kpsi. The electrode includes a nickel free steel sheath with a carbon content of less than 0.05% of the sheath and a core in the range of 13-17% of the electrode wherein the core includes primary alloy particles of iron, manganese, magnesium and nickel with a minor amount of secondary alloy particles of a silicon alloy and a boron alloy in a rutile based slag system. The nickel has a controlled amount in the general range of 1.0-2.0% by weight of the electrode and the rutile is 40-60% by weight of the core.
Patent CA-2532420-C (CA)
Inventor: ARAFAT HUSAM R
IPC: B64C3/26
Filed: 2003-08-27
Granted: 2010-02-09
Abstract: La présente invention concerne peau de protection (143a, 143b) destinée à un aéronef. Cette peau de protection (143a, 143b) forme les bords d'attaque des ailes, de des stabilisateurs horizontaux, et des dérives verticales. Une partie du matériau de cette peau (143a, 143b) est retirée selon un motif sélectionné (155a, 157a, 159a, 161a, 155b, 157b, 159b, 161b) de la surface intérieure de cette peau (143a, 143b). Dans un mode préféré de cette invention, la surface intérieure de la peau est chimiquement attaquée et/ou usinée mécaniquement dans des motifs ovales ou rectangulaires de façon à créer des zones froissées (155a, 157a, 159a, 161a, 155b, 157b, 159b, 161b) et générer un défaut progressif du métal. Ceci permet au bord d'attaque d'absorber l'énergie du choc lors d'une collision avec un oiseau ou un autre objet et, empêche l'oiseau ou l'autre objet de pénétrer à travers le bord d'attaque dans la sous structure.
Patent CA-2538775-C (CA)
Title: Methods of operating a series hybrid vehicle
Inventor: GRAY CHARLES L JR
IPC: B60L50/13
Filed: 2004-09-03
Granted: 2013-08-27
Abstract: The invention is directed toward methods for operating a series hybrid vehicle in a manner that responds to the operator's demand for power output, while maximizing engine efficiency and minimizing disruptions in vehicle drivability. According to the present invention, when the driver of a series hybrid vehicle makes a demand for power output, whether the secondary power source(s) (12) is supplied with secondary energy stored in an energy storage device(s) (14), direct input energy generated by an engine(s) (16), or both, depends on the amount of available secondary energy stored in the vehicle's secondary storage device(s) alone, and in combination with vehicle speed.  During the time that the engine is used to generate secondary energy, the power efficiency level at which the engine is operated also depends on the vehicle speed and the amount of available secondary energy stored in the vehicle's secondary storage device alone, and in combination with vehicle speed.
Patent CA-2541988-C (CA)
Inventor: JEMELIN VINCENT
IPC: A61C8/00
Filed: 2004-10-15
Granted: 2013-04-16
Abstract: The present invention relates to a package for preserving a medical device or the like comprising an external capsule and a cap sealingly engaging the external capsule, wherein a means is provided for releasingly connecting medical device with the cap upon removing the cap and the medical device from the external capsule. In a variation the package may comprise in addition a transport means surrounded by the cap and extending therein, wherein the transport means is adapted for releasingly connecting to the medical device.  Also a seal may be provided at an opening of the external capsule.
Patent CA-2544630-C (CA)
Title: Method and material for enhanced tissue-biomaterial integration
Inventor: RATCLIFFE ANTHONY
IPC: A61K35/32
Filed: 2004-10-09
Granted: 2013-01-08
Abstract: The present invention provides a composition and method for the covalent binding of a hydrogel to an extracellular matrix (ECM). Therapeutic applications include tissue repair and delivery of drugs or cells.
Patent CA-2547672-C (CA)
Inventor: HADA FRANK STEPHEN
IPC: D21F11/14
Filed: 2004-09-20
Granted: 2012-03-13
Abstract: A tissue product having a combination of substantially equal tensile energy absorbed (TEA) in the machine direction and the cross-machine direction of the tissue sheet and a significant level of stretch in both directions provides improved perception of strength and resistance to "poke through" in use. TEA  is calculated as the area under the stree-strain curve for the tissue sheet.  Poke through resistance of the tissue sheet is also represented by a normalized burst strength of from 20 to 40 cm.
Patent CA-2552354-C (CA)
Inventor: TESLUK CHRISTOPHER
IPC: A61H23/04
Filed: 2005-02-23
Granted: 2010-07-06
Abstract: A fluid conduit connector apparatus (10), which is adapted for use in a pneumatic system, comprises a connector (12) including a port portion (16) having a valve (76) disposed therein. The valve (76) moves to provide a reduced fluid orifice when a fluid conduit (18) is removed from the port (16).  The reduce d fluid orifice is configured to provide pneumatic characteristics as those of the apparatus (10) having the fluid conduit (18) connected to the part (16), so that uninterrupted operation of a timed pressure source having pneumatic sensing capabilty is facilitated.
Patent CA-2552408-C (CA)
Inventor: MAEAETTAE PAEIVI
IPC: B31B50/66
Filed: 2005-01-12
Granted: 2012-10-30
Abstract: The invention relates to a method and an apparatus for jointing members made of plastic-coated paper or board. In accordance with the invention, the sealable members are retained in position with clamps (8) and sealing is performed with a laser sealing means (7) moving along the sealing line, a means (9) for opening the seal point pressing the members apart to continue keeping the seal point open, a laser beam (11) being directed to the open seal point for melting the coating plastic and a means (12) for closing the seal pressing finally the members against each other, the plastic jointing the members when solidified. The method is applicable to lateral sealing of bag or container packages formed of blanks (1), among other things.
Patent CA-2555879-C (CA)
Inventor: NIIRANEN HEIKKI
IPC: D21H27/42
Filed: 2005-02-11
Granted: 2011-11-15
Abstract: The invention relates to a procedure and an apparatus in dry formation of a fibre layer, in which procedure fibre-containing air is passed through a forming wire (7) moving via a former (2) or an equivalent distributor unit and further through a suction box (8) or equivalent placed below the forming wire, and which air is circulated back to the upper part of the same or another former. In the solution of the invention, the air circulated through the suction box (8) is passed to the upper part of the former via channels (17) with an adjustable flow rate.
Patent CA-2561288-C (CA)
Title: Releasable toilet seat assembly
Inventor: VIERKANT ERICH C III
IPC: A47K13/26
Filed: 2005-03-30
Granted: 2011-09-27
Abstract: A mount assembly releasable mounts a toilet seat and cover to a toilet base.  The assembly includes two fasteners permanently affixed to the toilet base engaged by deflectable arms of one or two base members of the mount assembly.  The arms engage ring mounts disposed about the fastners, flexing outward slightly during mounting and dismounting achieved by a simple horizontal sliding motion. When connected, hinged covers snap onto the pair of arms to cover the fasteners and prevent deflection of the arms and thus separation of the base member(s) from the fasteners.
Patent CA-2564029-C (CA)
Title: Interface and communication protocol for a mobile device with a smart battery
Inventor: GUTHRIE MARTIN
IPC: G06F1/26
Filed: 2006-10-13
Granted: 2013-07-09
Abstract: Various embodiments are described herein for a mobile communication device that utilizes a smart battery. The mobile device includes a main processor for controlling the operation of the mobile communication device. The smart battery is coupled to the main processor and provides supply power. The smart battery includes a battery processor for controlling the operation of the smart battery and communicating with the main processor, and a battery module having one or more batteries for providing the supply power. A battery interface is provided for coupling between the main processor and the battery processor for providing communication therebetween. The battery interface comprises a data communication line and protection circuitry for protecting the main processor from electrostatic discharge. A communication protocol is also provided for communication between the main processor and the battery processor.
Patent CA-2568750-C (CA)
Inventor: FRIEDLANDER MARTIN
IPC: A61K38/19
Filed: 2005-06-06
Granted: 2014-05-27
Abstract: The present invention provides compositions and methods of treating neovascular diseases, such as a retinal neovascular diseases and tumors, by administering to a patient suffering from a neovascular disease or tumor a vascular development inhibiting amount of a combination of the angiogenesis suppressing drugs comprising an angiostatic fragment of tryptophanyl-tRNA  synthetase (TrpRS) and at least one compound selected from the group consisting of a vascular endothelial growth factor (VEGF) signaling inhibitor and an integrin signaling inhibitor. Compositions for use in the methods include an admixture of an angiostatic fragment of tryptophanyl-tRNA  synthetase (TrpRS) and at least one of a vascular endothelial growth factor (VEGF) signaling inhibitor and an integrin signaling inhibitor, together with a pharmaceutically acceptable excipient.
Patent CA-2570759-C (CA)
Inventor: HARNETIAUX TRAVIS L
IPC: A01C15/00
Filed: 2006-12-11
Granted: 2014-01-14
Abstract: A tensioning arrangement to an endless linkage of a drive train is provided. The tensioning arrangement includes a tension arm and a spool mounted at the tension arm. The spool includes a rib generally centrally located between opposing first and second endwalls of the spool. The rib includes a greater outer diameter relative to an outer diameter of adjacent cylindrical portions abutting the rib. Both opposing first and second endwalls of the spool are of greater outer diameter so as to steer the endless linkage therebetween in general alignment with the rib. A spring includes a hook free end engaged at the tension arm, and a linear shaped free end engaged at the frame so as to bias the spool against the endless linkage.
Patent CA-2571222-C (CA)
Title: Control panel apparatus
Inventor: YAMAMOTO TAKAO
IPC: H01R13/52
Filed: 2006-12-15
Granted: 2011-06-21
Abstract: To make it possible to easily recognize, from an external appearance, whether or not a waterproof tight-sealing level of a coupler penetrating a meter case is adequate. A coupler which is fixed to a meter case (lower case) includes a sleeve which penetrates the case and a flange which overhangs from the sleeve to a circumference thereof. An annular groove holding a seal ring is provided in the flange. A step as a mark is provided on an outer circumference of the sleeve in order that an adequate compression amount of the seal ring can be recognized from the external appearance. This step is aligned with an outer surface of the lower case when the seal ring is compressed up to the adequate compression amount.
Patent CA-2580272-C (CA)
Title: Control system for automatic flight in windshear conditions
Inventor: SHUE SHYHPYNG JACK
IPC: B64C13/16
Filed: 2005-10-11
Granted: 2010-12-21
Abstract: A flight control system is configured for controlling the flight of an aircraft through windshear conditions. The system has means for measuring values of selected flight performance states of the aircraft and a control system for operating flight control devices on the aircraft. A windshear detection system located on the aircraft uses at least some of the measured values of the selected flight performance states to calculate a gust average during flight for comparison to pre-determined values in a table for determining whether windshear conditions exist. The control system then operates at least some of the flight control devices in response to an output of the windshear detection system.
Patent CA-2581063-C (CA)
Inventor: GODFREY WAYNE R
IPC: C12N5/0783
Filed: 2005-09-14
Granted: 2016-03-22
Abstract: The present invention encompasses methods, and kits for the isolation and expansion of T regulatory cells having the CD45RA+ phenotype,including such cells from human umblical cord blood.
Patent CA-2582283-C (CA)
Title: Water heater with flammable vapor sensor
Inventor: GARRABRANT MICHAEL A
IPC: F24H1/18
Filed: 2007-03-20
Granted: 2011-05-24
Abstract: A water heater including a water container, a combustion chamber adjacent the water container, a burner associated with the combustion chamber, a blower located to receive combustion products generated by the burner, an intake air conduit connected to the combustion chamber and having a combustion air intake opening, a dilution air conduit connected to the blower and having a dilution air intake opening; and a flammable vapor sensor having at least an operative portion positioned in the blower or the dilution air conduit.
Patent CA-2586265-C (CA)
Inventor: BOHLMANN ROLF
IPC: C07D401/12
Filed: 2005-10-28
Granted: 2013-08-06
Abstract: The invention relates to novel nicotinamide pyridinureas as VEGF  receptor kinase inhibitors, their production and use as pharmaceutical agents for preventing or treating diseases that are triggered by persistent angiogenesis. In one aspect of the invention, the nicotinamide pyridinureas are compounds of the general formula (I):  (see formula I) or an isomer, diastereoisomer, enantiomer, tautomer or salt thereof.
Patent CA-2588247-C (CA)
Inventor: FRY KEVIN D
IPC: A47L5/36
Filed: 2006-02-28
Granted: 2014-05-13
Abstract: The disclosed vacuum cleaner (10) has a smaller, separable vacuum unit (30) that is releasably attached to a larger, base unit tank assembly (11). It provides a combination vacuum cleaner that has small- and large- capacity configurations suited for vacuum applications having different volumes, locations, or other features. The vacuum cleaner includes a single vacuum source sized for use with the larger tank structure, yet coupled to and removable integrally with the smaller vacuum unit. The smaller vacuum unit can be quickly and easily attached to and removed from the larger tank assembly to facilitate use of the vacuum cleaner in the desired configuration.
Patent CA-2597938-C (CA)
Inventor: BROCARD JEAN-MARIE
IPC: F02C7/22
Filed: 2006-02-17
Granted: 2014-09-23
Abstract: The invention concerns a centrifugal pump (100) driven by being mechanically coupled with the engine (14) has a low pressure input receiving fuel from a fuel circuit (11) of the aircraft and a high pressure output connected to a circuit (120) regulating the flow of fuel supplied to the engine, and an electrically-controlled auxiliary pumping unit (10) having an input connected to the aircraft fuel circuit and an output connected to the flow regulating circuit, to deliver on its fuel output at a predetermined minimum pressure, the pressure of the fuel supplied to the regulating circuit being the highest of those delivered by the centrifugal pump (100) and the auxiliary pumping unit (110).
Patent CA-2599114-C (CA)
Inventor: TRAN PASCALINE H
IPC: B01J23/648
Filed: 2006-01-30
Granted: 2013-08-20
Abstract: A process is described that removes by oxidation the excess ammonia (NH3) gas from flue gases that have been subjected to selective catalytic reduction (SCR) of oxides of nitrogen (NOx) by ammonia injection. The inventive process incorporates a secondary catalyst of precious metal and vanadia on a metal oxide such as titania to catalyze the oxidation of both ammonia and carbon monoxide (CO) while maintaining sulfur dioxide (SO2) levels.
Patent CA-2602043-C (CA)
Inventor: PATEL KIRIT M
IPC: B01D53/02
Filed: 2006-03-29
Granted: 2013-04-30
Abstract: A process for the purification of hydrogen based gas mixtures utilizing zeolite X wherein the particle size distribution of the zeolite X powder has a coefficient of variation from 15% to 30%.
Patent CA-2602788-C (CA)
Title: Ski sock
Inventor: LIBERMAN BARNET L
IPC: A41B11/00
Filed: 2006-03-30
Granted: 2011-01-18
Abstract: A sock (10) has a leg portion, a heel portion (12), an instep portion (16), a toe portion (18), a pair of lateral metatarsal joint portions (20) where the instep portion (16) meets the toe portion (18). The sock (10) has a first material thickness at the inslep portion (16) and the toe portion (18), and a second materaial thickness at at least one of the lateral metatrsal joint portions (20) wherein the second material thickness is less than the first materail thickness.
Patent CA-2603510-C (CA)
Title: Lentilles de contact photochromiques et procedes de production associes
Inventor: MOLOCK FRANK F
IPC: G02B1/04
Filed: 2006-03-23
Granted: 2015-03-17
Abstract: La présente invention concerne une composition photochromique conçue pour être utilisée dans les lentilles de contact de coloration dans laquelle le polymère liant utilisé est capable de former un réseau polymère interpénétrant avec le matériau de lentille. Lorsque les compositions photochromiques de l~invention sont appliquées au matériau de lentille non durcie et ensuite durcie, le polymère liant forme un réseau polymère interpénétrant avec le matériau de lentille incorporant le composé photochromique à l~intérieur du matériau de lentille pour produire une lentille photochromique stable.
Patent CA-2603549-C (CA)
Title: Dispositif ophtalmiques comportant des matieres photochromiques contenant des substituants reactifs
Inventor: WENJING XIAO
IPC: C09K9/02
Filed: 2006-04-03
Granted: 2014-02-11
Abstract: La présente invention se rapporte à des dispositifs ophtalmiques comportant des matières photochromiques contenant un substituant réactif. La présente invention se rapporte par exemple à des dispositifs ophtalmiques comportant des matière photochromiques, du type naphtopyranes et naphtopyranes indeno-fusionnés photochromiques ayant un substituant réactif comprenant un fragment réactif lié au naphtopyrane photochromique par un ou plusieurs groupes de liaison. Dans certains modes de réalisation non limitatifs, le fragment réactif comprend un fragment polymérisable. Dans d'autres modes de réalisation non limitatifs, le fragment réactif comporte un fragment nucléophile. D'autres modes de réalisation non limitatifs de la présente invention se rapportent à des procédés de fabrication de ce dispositif ophtalmique photochromique, selon lesquels les dispositifs ophtalmiques photochromiques comportent ces naphtopyranes photochromiques.
Patent CA-2604327-C (CA)
Title: Composition pharmaceutique sous forme d'aerosol
Inventor: KELLER MANFRED
IPC: A61K9/12
Filed: 2006-04-06
Granted: 2013-10-15
Abstract: La présente invention a trait à des compositions stériles pour administration sous forme d'aérosols. Elles contiennent un principe actif qui est très peu hydrosoluble, un constituant tensioactif non ionique et un constituant phospholipidique. Les compositions conviennent à l'inhalation orale ou nasale, mais également pour une administration topique ou oromucosale. Elles sont particulièrement utiles pour une administration pulmonaire efficace de corticostéroïdes et peuvent être formulées sous forme d'aérosol avec des nébuliseurs classiques.
Patent CA-2607002-C (CA)
Title: Dispositif de commande de vehicule
Inventor: TAKENAKA TORU
IPC: B60W10/20
Filed: 2006-08-07
Granted: 2011-07-26
Abstract: La présente invention concerne un moyen de commande (10) destiné à commander les opérations d~actionneurs (3A, 3B, 3C) d~un véhicule (1), le moyen de commande créant une série chronologique de comportement futur du véhicule (1) en utilisant un modèle de véhicule (41). En l~occurrence, une quantité d~état du modèle de véhicule (41) est initialisée selon la quantité d~état du véhicule proprement dit (1) et le comportement futur est créé à partir de la quantité d~état initiale. Le comportement futur est créé en alignant l~instruction d~opération des actionneurs du modèle de véhicule (41) à l~instant présent sur une valeur de base en fonction de l~opération d~un opérateur (5) tel qu~un volant de direction du véhicule (1). Il est jugé si les objets d~évaluation tels que le mouvement du véhicule, la force de réaction de la surface de roulement et le patinage des roues, selon le comportement futur créé, satisfont ou non à des conditions prédéterminées. Selon les résultats de l~évaluation, les instructions d~opération des actionneurs (3A, 3B, 3C) sont successivement décidées. Il est ainsi possible de prédire correctement le comportement futur du véhicule et de permettre une conduite appropriée du véhicule.
Patent CA-2610841-C (CA)
Title: Procede et agencement permettant de monter un capteur concu pour mesurer la distance entre un stator et un rotor
Inventor: AKERBLOM BENGT
IPC: B02C7/14
Filed: 2006-05-22
Granted: 2013-09-17
Abstract: La présente invention concerne un capteur (6) permettant de mesurer la distance entre un stator et un rotor, ce capteur étant de type magnétique possédant un corps de capteur (8) sur lequel est fixé une tête de capteur (10), cette tête de capteur (10) étant connectée au corps de capteur (8) par un agencement de fixation (14) qui possède un dispositif de verrouillage (16) lequel interagit avec des dispositifs de mise en contact (24) et un agencement de ressort (34). Ce dispositif de verrouillage (16) est pressé en direction d'une position d'attache (A) par l'action d'une force ressort FI exercée par l'agencement de ressort (34) contre le dispositif de mise en contact (24), fixant le corps de capteur (8) et la tête de capteur (10) en relation mutuelle. Par l'application d'une force F2 sur le corps de capteur (8) supérieure à la force ressort FI, il est possible de déplacer le corps de capteur et la tête de capteur dans une position de libération (D), libérant ces derniers de leur relation mutuelle.