baber/WOPTO huggingface dataset:
Patent CA-2117421-C (CA)
Inventor: BRADFORD ROBERT W
IPC: G02B21/00
Filed: 1992-01-29
Granted: 1998-05-05
Abstract: A microscopy system designed to achieve upwards of 12,000X magnification with simultaneous high resolution of better than 0.3 microns and over 30 microns depth-of-field. The microscopy system utilizes a conventional research microscope having a plurality of objective magnification lenses that produce the initial magnification with acceptable limits of high resolution and depth-of-field.  A projection housing is combined with the research microscope in a unique manner where it receives the initial magnification and greatly increases that magnification while still maintaining the high resolution and depth-of-field obtained during the initial magnification.  A light source used to illuminate the specimen platform from its underside is located remotely therefrom and connected by a fiber optic cable to a condensing lens positioned beneath the specimen platform.  This allows for high intensity lighting of the specimen while keeping it away from the detrimental heat of the source of high intensity light.  The projection housing has projected image receiving means therein whose distance from its projection lens can be varied to vary the magnification produced by projection.
Patent CA-2118569-C (CA)
Title: Medication dispensing device
Inventor: MICHEL PETER
IPC: A61M5/28
Filed: 1994-03-08
Granted: 2005-02-01
Abstract: A medication dispensing device comprising a cartridge for containing an injectable product therein and an injector attached to the cartridge. The injector includes a drive mechanism comprising a dosage sleeve having a dosage knob at the proximal end thereof and a threaded rod coupled to the sleeve and axially advanceable into the cartridge upon clockwise rotation of the knob for dialing up a desired dosage to be injected. A ratchet mechanism is disposed in the injector housing and includes a rotatable piece secured to the dosage sleeve for rotation therewith and a locking seat in engagement with the rotatable piece. The ratchet mechanism permits rotational movement of the sleeve in the clockwise direction only. A disengaging mechanism is secured to the housing of the LCD assembly and includes a pin that extends into and engages the rotatable piece of the ratchet mechanism such that axial movement of the pin causes corresponding axial movement of the stationary piece. Upon depressing the outer surface of the disengaging mechanism, the pin and the rotatable piece are moved axially away from the seat sufficiently enough to permit a user to rotate the dosage knob in a counterclockwise direction to accurately dial back an accidental overdose measurement without removing the cartridge from the injector.
Patent CA-2118597-C (CA)
Inventor: KRUSE PAUL W JR
IPC: H01L37/02
Filed: 1992-11-03
Granted: 2001-12-11
Abstract: A thin film pyroelectric imaging array (N, M) fabricated as a Si wafer. A thin film (40) of PbTiO3 is deposited on a ther-mally isolated bridge (45). The bridge (45) suspends the PbTiO3 sensor (40) over a preferentially etched cavity (70) in the Si wafer (10). Improved thermal isolation increases the responsivity of the sensor (33) to incident radiation. The pyroelectric sensor (33) formed can operate effectively at room temperature.
Patent CA-2119778-C (CA)
Inventor: ADDEO ERIC JOHN
IPC: H04M9/08
Filed: 1992-09-03
Granted: 1997-06-03
Abstract: An audio processing system (100) for use in a teleconferencing system (10) utilizes complementary comb filters (42, 52, 220, 320) in combination with an echo suppressor (210, 310) and/or a frequency scaler (60, 120) to substantially improve acoustic stability margin and reduce far-end talker echo.
Patent CA-2121023-C (CA)
Inventor: HOROWITZ ALLAN J
IPC: A47G27/02
Filed: 1994-04-11
Granted: 1998-06-16
Abstract: A mat adapted to relieve fatigue in a person standing on it without shoes or boots, and formed from fine cell foam having a density of between 1.5 and 2.5 pounds per cubic foot, with thickness between 0.75 and 1.5 inches, and a compression strength at 25% compression of between 10 and 17 p.s.i.  The mat has sloping edges and is covered by carpet.  When a person in bare or stocking feet stands on the mat, the mat partially compresses but has remaining resiliency such as to produce a swaying motion in the person.  This results in increased muscle action and blood circulation in the feet, legs and hips and some spinal movement, reducing fatigue.
Patent CA-2123725-C (CA)
Inventor: SHUKNECHT LEE N
IPC: A01D31/00
Filed: 1994-05-17
Granted: 1997-05-13
Abstract: A machine for harvesting onions utilizes a blower which provides a stream of air through a duct, having an opening across which the onions pass and are topped.  The blower has a bladed fan in a cylindrical housing open at both ends.  The fan blades are supported by arms which, with the blades, define a support truss for each blade in the form of a triangular structure, having arms meeting at an apex connected approximately midway of the end of the cylindrical housing and a base provided by the blade to which the arms are connected.  A rigid support is provided together with an enlarged and substantially unobstructed intake passageway for air along the axis of rotation of the fan which is pressurized and forced through the duct, using less horsepower and fuel than conventional fans of like size and air flow.  The air flow is controllable in air pressure by a shear plate which is moveable into and out of the cylindrical housing and the air direction is adjustable by a vane provided by a sidewall of the duct adjacent to the outlet and may also be controlled in direction by vanes in a hood over the duct outlet.
Patent CA-2124967-C (CA)
Title: Transgenic non-human animals capable of producing heterologous antibodies
Inventor: LONBERG NILS
IPC: A61K38/00
Filed: 1992-12-17
Granted: 2008-04-08
Abstract: The invention relates transgenic non-human animals capable of producing heterologous antibodies and transgenic non--human animals having inactivated endogenous immunoglobulin genes. In one aspect of the invention, endogenous immunoglob-ulin genes are suppresed by antisense polynucleotides and/or by antiserum directed against endogenous immunoglobulins.  He-terologous antibodies are encoded by immunoglobulin genes not normally found in the genome of that species of non-human animal. In one aspect of the invention, one or more transgenes containing sequences of unrearranged heterogolous human immu-noglobulin heavy chains are introduced into a non-human animal thereby forming a transgenic animal capable of functionally rearranging transgenic immunoglobulin sequences and producing a repertoire of antibodies of various isotypes encoded by hu-man immunoglobulin genes. Such heterologous human antibodies are produced in B-cells which are thereafter immortalized, e.g., by fusing with an immortalizing cell line such as a myeloma or by manipulating such B-cells by other techniques to perpetuate a cell line capable of producing a monoclonal heterologous antibody. The invention also relates to heavy and light chain immunog-lobulin transgenes for making such transgenic non-human animals as well as methods and vectors for disrupting endogenous im-munogiobulin loci in the transgenic animal.
Patent CA-2129607-C (CA)
Title: Process for the production of a precipitated silica
IPC: A61K8/00
Filed: 1994-08-05
Granted: 1999-03-09
Abstract: Precipitated silica which has a BET surface area of 10-130 m2/g, a CTAB surface area of 10-70 m2/g, an average particle diameter of 5-20 µm, a Cu abrasion value in a 10% glycerol dispersion of 4-50 mg and thickening behavior in a CMC solution (20% dispersion) of 300-3500 mPa.s, is produced by this invention.  The process comprises simultaneously adding alkali metal silicate (weight modulus SiO2:alkali metal oxide = 2.5-3.9:1) and a mineral acid to an initial amount of water which has been adjusted to a pH value of 7.0 to 9.9 or 10.0 to 10.7 by the addition of water glass (sodium silicate).  The pH value is held constant between 7.0 to 9.9 or 10.0 to 10.7 during addition of the alkali metal silicate and mineral acid.  The initial precipitation temperature is 50°-90° C. and an increase in viscosity occurs after at most 25% of the duration of precipitation.  The pH value is adjusted to ~ 6, preferably 3.5, once a silica content of greater than 120 g/l or greater than 150 g/l, preferably ~ 160 g/l to 240 g/l, has been reached.  The solid is separated by filtration, washed, dried and ground.  The precipitated silica may be used as an abrasive and/or thickening component in toothpastes.
Patent CA-2131087-C (CA)
Inventor: BARRERE GENEVIEVE
IPC: C12N1/20
Filed: 1993-03-31
Granted: 2008-12-02
Abstract: This invention relates to micro-organisms capable of selectively producing streptogramin components A and B, the preparation of said micro-organisms, and streptogramin A or B.
Patent CA-2136070-C (CA)
Inventor: BENDIAK BRAD K
IPC: C07H15/04
Filed: 1993-06-01
Granted: 1997-06-03
Abstract: Methods are provided for the sequential removal of monosaccharides from the reducing end of oligosaccharides. The pres-ent invention also discloses the use of such methods for structural determinations of oligosaccharides and to enable new struc-tures to be generated from pre-existing oligosaccharides. In addition, the methods of the present invention may be automated by the incorporation into systems.
Patent CA-2138677-C (CA)
Inventor: MAILHOT WALTER L
IPC: B25H7/02
Filed: 1994-12-21
Granted: 2005-07-05
Abstract: An improved versatile measuring device for measuring linear, and angular dimensions and defining relative positional parameters or coordinates between a plurality of lines, points, or surfaces on a plane and for determining and duplicating line lengths and relative angular positions of any number of lines, points or surfaces. The measuring device has protractor members each of which is rotatably and clampably attached to a connecting member which itself is linearly extendible and may also be altered to have a pivoting point about which a main arm and an extendible arm of the connecting member are pivotal and clampable with respect to each other. Each of the protractor ends also has an edge-guide slot substantially parallel to a scribe edge. Slideably mountable onto each of the edge-guide slots is at least one edge-guide pin each of which is positionally adjustable and securable within an edge-guide slot. The pins provide an edge reference useful for the repeated and consistent layout and marking of an article such as stair stringers or roof rafters which are being prepared for use.
Patent CA-2141467-C (CA)
Title: Coiling machine for coiling a continuous paper web
Inventor: SOLLINGER HANS-PETER
IPC: B65H18/26
Filed: 1995-01-31
Granted: 2002-08-20
Abstract: There is provided a coiling machine for coiling a continuous paper web having two large rolls that form a coil bed for uptake of a paper coil. The space bounded by the large rolls and the coil is formed as a pressure-tight chamber that has a compressed air connection.      Particularly for the present invention, one of the two large rolls has a jacket that is essentially more intensely deformable than the jacket of the other roll and, thus, one large roll is softer than the other large roll. The upper vertex of the softer large roll is located lower than the upper vertex of the harder large roll. The web guidance is configured for one embodiment of the coiling machine such that the web is introduced from below, and between the two large rolls, to wind around the softer large roll. For another embodiment of the coiling machine, the web is introduced through a pressing gap between one of the large rolls and the coil.
Patent CA-2144527-C (CA)
Title: Up-converting reporters for biological and other assays using laser excitation techniques
Inventor: ZARLING DAVID A
IPC: G01N33/536
Filed: 1993-09-14
Granted: 2010-08-17
Abstract: The invention provides methods, compositions, and apparatus for performing sensitive detection of analytes, such as bio-logical macromolecules and other analytes, by labeling a probe molecule with an up-converting label. The up-converting label ab-sorbs radiation from an illumination source and emits radiation at one or more higher frequencies, providing enhanced signal-to-noise ratio and the essential elimination of background sample autofluorescence. The methods, compositions, and apparatus are suitable for the sensitive detection of multiple analytes and for various clinical and environmental sampling techniques.
Patent CA-2145313-C (CA)
Title: Antimicrobial peptides
Inventor: SHAFER WILLIAM
IPC: A61P31/04
Filed: 1993-10-01
Granted: 1999-09-21
Abstract: Peptides which exhibit antimicrobial activity comparable to certain known antibiotics are provided. These peptides are related in sequence to amino acid sequences within Cathepsin G. A broad spectrum bactericidal peptide disclosed herein is RPGTLCTVAGWGRVSMRRGT (SEQ ID NO:4); it is active against Pseudomonas aeruginosa, Neisseria gonorrhoeae and Staphylococcus aureus. RRENTQQHITARRAIRHPQY (SEQ ID NO:7) and GKSSGVPPEVFTRFVSSFLPWIRTTMR (SEQ ID NO:8) also exhibited potent activiy against P. aeruginosa strains, including clinical isolates. The peptides of the present invention will be useful in pharmaceutical compositions useful in the treatment or prophylaxis of infections.
Patent CA-2145596-C (CA)
Inventor: RAMIN ROLAND
IPC: A61K8/73
Filed: 1995-03-27
Granted: 1999-06-29
Abstract: La présente invention concerne une composition de soin à appliquer sur l'ongle comprenant des composés susceptibles d'aider à sa restructuration et à son embellissement.
Patent CA-2150857-C (CA)
Inventor: DILL ROLAND
IPC: H03H9/64
Filed: 1995-06-02
Granted: 1998-12-29
Abstract: A filter operating with acoustical surface waves includes two acoustical paths each having one unidirectional input trans-ducer, one unidirectional output transducer, and a reflector structure disposed between the input and output transducers.          The input transducers in the acoustical paths are structurally identical, the output transducers in the acoustical paths are structurally identical, and the input and output transducers in each of the acoustical paths are spaced apart by the same distance.  One of the input transducers or the output transduc-ers are electrically connected in phase opposition, and the other of the input transducers or the output transducers are electrically connected in phase.  The reflector structures in the two acoustical paths have substantially the same reflection performance, the reflector structure in one of the acoustical paths is shorter than the reflector structure in the other of the acoustical paths by .lambda./2, the reflector structures in the two acoustical paths are disposed centrally between the input and output transducers, and .lambda. is a wavelength at a mean fre-quency of the filter.
Patent CA-2152446-C (CA)
Inventor: LINN C PRESTON
IPC: C12Q1/6816
Filed: 1995-06-22
Granted: 1999-08-17
Abstract: The present invention relates to conjugates of a cyanine dye and an oligonucleotide. When these conjugates hybridize or bind to a target, a detectable increase in fluorescence intensity or change in fluorescence polarization is observed.
Patent CA-2153523-C (CA)
Inventor: FLYNN STEPHEN
IPC: A61M16/20
Filed: 1995-07-10
Granted: 2006-06-06
Abstract: A CPR face mask has a substantially toroidal face engaging pan positionable on the face of a patient to surround at least the mouth of the patient. A flexible generally conical part having a lower end extending around and is secured to an upper surface of the face engaging part, and an upper end with an aperture through which a CPR giving person can blow air which passes downwardly through the conical part and the toroidal part into the patient's mouth. The flexible generally conical part has a relatively short outwardly extending substantially horizontal portion at the lower end extending around and secured to the upper surface of the face engaging part, a relatively short portion extending upwardly and outwardly from an inner edge of the substantially horizontal portion, a relatively high frusto-conical portion extending upwardly and inwardly from an upper edge of the upwardly and outwardly inclined portion, a relatively short portion extending inwardly and downwardly from an upper edge of the frusto-conical portion and a central cylindrical portion extending upwardly from an inner edge of the inwardly and downwardly extending portion and providing said aperture. The mask can be positioned in a collapsed configuration for storage by downward movement of the central cylindrical portion to cause the frusto-conical portion to fold downwardly and extend into the toroidal face engaging part and can be-returned to a ready-to-use configuration by an upward pull on the central cylindrical portion.
Patent CA-2154933-C (CA)
Inventor: GARDNER GREGORY P
IPC: E04G21/16
Filed: 1995-07-28
Granted: 2000-05-02
Abstract: An apparatus and method for dispensing and applying flexible sheet material, such as house wrap, from an elongate roll in a substantially continuous manner to the planar surface of a structure.
Patent CA-2157664-C (CA)
Title: Procede d'obtention d'une huile ultrapure a base d'oeuf et son utilisation
Inventor: NAWROCKI WERNER C
IPC: A61K8/00
Filed: 1995-02-20
Granted: 2005-05-24
Abstract: On produit une huile à base d'oeuf de grande pureté à partir de jaune d'oeuf séché et pulvérisé d'oiseaux ou de reptiles par extraction, à l'aide de solvants de graisse, par vieillissement en deux phases d'abord à la température ambiante puis à une température inférieure, par séparation et centrifugation de la phase de basse viscosité ainsi obtenue, et, par une autre séparation de la fraction de basse viscosité. On mélange ensuite cette fraction éventuellement plusieurs fois avec de l'eau déminéralisée avant de la chauffer, la phase de basse viscosité étant à nouveau centrifugée après refroidissement et séparation. Après une autre séparation de la fraction à faible viscosité, cette dernière est maintenue à une faible température, la fraction de basse viscosité séparée étant à nouveau centrifugée après une séparation de phase supplémentaire. On obtient ainsi encore une séparation de phase, la fraction de basse viscosité séparée constituant le produit fini, soit une huile adaptable, de couleur jaune à rouge, et pouvant être conservée sans agents conservateurs. L'huile à base d'oeuf de grande pureté produite selon l'invention peut être utilisée pour traiter les brûlures de la peau, dont les coups de soleil, et pour régénérer l'épiderme dans les produits cosmétiques.
Patent CA-2158091-C (CA)
Title: Dryer-activated fabric conditioning compositions containing unsaturated fatty acid
Inventor: CORONA ALESSANDRO III
IPC: C11D3/20
Filed: 1995-09-12
Granted: 1999-11-09
Abstract: The present invention relates to dryer-activated fabric softening compositions and articles, having improved antistatic and/or softening effects, for use in an automatic clothes dryer, especially those comprising, as essential ingredients: (A) fabric softener consisting essentially of (1) from about 5% to about 95% of preferably biodegradable quaternary ammonium compound selected from the group consisting of the compounds of Formula I: (R)4-m~ N+~[(CH2)n ~Y~R2]m X-; wherein each Y is ~OC(O)~ or ~C(O)~O~; m is 1 to 3; each n is an integer from 1 to 4; each R substituent is a short chain C1-C6 alkyl; a short chain C1- C4 hydroxyalkyl group, benzyl, or mixtures thereof; each R2 is a long chain, saturated or unsaturated with an Iodine Value (IV) of from about 3 to about 60, C8-C30 hydrocarbyl, or substituted hydrocarbyl substituent; and the counterion, X-, is any softener-compatible anion; Formula II: (R1)3-N+~(CH2)n~ C(YR2)H~ C(YR2)HZ X-; wherein, for any molecule: each Y is ~OC(O)~, or ~C(O)~O~; each R1 is C1-C4 alkyl or hydroxy alkyl; and R2, X-, and n are as previously defined in Formula I; Formula III: (R)4-m ~N+~[(CH2)n~ Y~R2]m X-, wherein R, R2, m, n, and X- are as previously defined in Formula I; and each Y is -NH-C(O)-; -C(O)-NH-; -C(O) -O-; or ~O~C(O)- wherein at least one Y group is -NH-C(O)- or -C(O)-NH-, and mixtures thereof; (2) from 0% to about 95% highly ethoxylated and/or propoxylated, preferably at least 5 ethylene oxide (EO) and/or propylene oxide (PO) groups per molecule, sugar derivative containing at least one long hydrophobic moiety per molecule, sugar derivative containing at least one long hydrophobic moiety per molecule, and (3) from 0% to about 95% of carboxylic acid salt of teriary amine; and (B) from about 1% to about 15%, unsaturated fatty acid having an IV of from about 3 to about 60. The amount of (A) present is at least sufficient to provide softening and/or antistatic effects. The active component(s) (A) can, and preferably do, contain unsaturation to provide improved antistatic benefits.
Patent CA-2160140-C (CA)
Title: Cycloalkylhydroxyurees et leur utilisation comme inhibiteurs de la lipoxygenase
Inventor: STEVENS RODNEY WILLIAM
IPC: A61P29/00
Filed: 1994-04-05
Granted: 1999-03-16
Abstract: La présente invention décrit un nouveau composé N-hydroxyurée de la formule chimique (I) dans laquelle R1 et R2 sont chacun indépendamment hydrogène ou alkyle C1-C4; Ar est phényle ou phényle mono, di ou trisubstitué; A est une liaison de valence ou une chaîne alkylène C1-C6, possédant éventuellement une double liaison ou une triple liaison dans la chaîne, et présentant éventuellement un ou plusieurs groupes alkyle C1-C4 fixés à la chaîne; X est oxygène ou soufre; n est un entier compris entre 3 et 6; M est hydrogène, un cation pharmaceutiquement acceptable ou bien un groupe métaboliquement clivable; et X et A peuvent être accolés à n'importe quelle position disponible sur le noyau. Ces composés sont utiles pour traiter ou atténuer les affections inflammatoires, les allergies et les maladies cardio-vasculaires chez les mammifères, et comme principe actif dans des compositions pharmaceutiques permettant de traiter de telles affections.
Patent CA-2163406-C (CA)
Title: Charge utile de satellite a canaux transparents integres
Inventor: FLOURY GERARD
IPC: H04B1/59
Filed: 1995-11-21
Granted: 2001-01-09
Abstract: Charge utile pour satellite à d canaux transparents comprenant en outre une première pluralité g de filtres de canal passe-bande IMUX de largeur .delta. qui filtrent des signaux reçus ; des moyens de transposition de fréquence, une pluralité k d'amplificateurs de canal, k ~ d ; des moyens d'amplification de puissance, et une deuxième pluralité p de filtres de canal OMUX qui filtrent les signaux amplifiés par les amplificateurs de canal et les amplificateurs de puissance, des moyens de redondance afin d'affecter d amplificateurs auxdits d canaux ; lesdits moyens de transposition de fréquence comprenant au moins un mélangeur et au moins une source d'un signal de fréquence de transposition, caractérisé en ce que lesdits g filtres IMUX de canal passe-bande filtrent lesdits signaux reçus avant la transposition de fréquence par lesdits moyens de transposition.
Patent CA-2179899-C (CA)
Inventor: GLINSKII GUENNADI V
IPC: C07H7/02
Filed: 1995-06-12
Granted: 2000-05-23
Abstract: La présente invention concerne une classe de molécules modifiant l'adhérence cellulaire. L'agent de modification d'adhérence cellulaire de la présente invention se compose essentiellement d'un acide aminé comportant une liaison avec un glucide, l'acide aminé et le glucide étant reliés de façon à former un composé appartenant au groupe constitué des bases de Schiff, des N-glycosides, des esters et des produits obtenus par transposition d'Amadori. Le glucide est de préférence un monosaccharide ou un petit oligosaccharide. Les sous-groupes glucide et acide aminé sont chimiquement modifiables. Par exemple, l'acide aminé peut être modifié par liaison covalente d'autres groupes au groupe amino, au groupe carboxyle, ou au groupe à chaînes latérales de l'acide aminé. Le sous-groupe glucide est de préférence un pentose tel que l'arabinose, le xylose, le ribose, le ribulose, un hexose tel que le fructose, le désoxyfructose, le galactose, le glucose, le mannose, le rhamnose ou un disaccharide construit sur deux glucoses tels que le maltose, le lactose, la maltulose ou le lactulose.