Patent SG-11201900154V-A (SG)
Title: Compounds, compositions, and methods for the treatment of disease
Inventor: IYER RADHAKRISHNAN
IPC: C07H21/04
Filed: 2017-07-14
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property MD 1101111 0 DOI HIM 011101 0 0111111111111111111111111111111111111111111111 Organization International Bureau (10) International Publication Number (43) International Publication Date .....0\"\" WO 2018/013908 Al 18 January 2018 (18.01.2018) W I P0 I P C T (51) International Patent Classification: TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, A61K 39/04 (2006.01) C07H 21/04 (2006.01) KM, ML, MR, NE, SN, TD, TG). A61K 39/39 (2006.01) (21) International Application Number: Declarations under Rule 4.17: PCT/US2017/042106 — of inventorship (Rule 4.17(iv)) (22) International Filing Date: Published: 14 July 2017 (14.07.2017) — with international search report (Art. 21(3)) — before the expiration of the time limit for amending the (25) Filing Language: English claims and to be republished in the event of receipt of (26) Publication Language: English amendments (Rule 48.2(h)) (30) Priority Data: 62/363,123 15 July 2016 (15.07.2016) US 62/411,405 21 October 2016 (21.10.2016) US (71) Applicant: SPEROVIE BIOSCIENCES, INC. [US/US]; 113 Cedar Street, Milford, MA 01757 (US). (72) Inventors: IYER, Radhakrishnan, P.; 15 Quail Hollow _ Drive, Shrewsbury, MA 01545 (US). PADMANABHAN, Seetharamaiyer; 67 Fottler Avenue, Lexington, MA 02420 (US). CLEARY, Dillon; 99 Spruce Street, Middleborough, — MA 02346 (US). MEHER, Geeta; 4 Capital Road # 1, Mil- ford, MA 01757 (US). GIMI, Rayomand, H.; 41 Stonegate = - Road, Chelmsford, MA 01824 (US). SHERI, Anjaneyu- = lu; 12 Pheasant Hill Drive, Shrewsbury, MA 01545 (US). - = ZHOU, Shenghua; 21 Stoney Hill Road, Shrewsbury, MA 01545 (US). CHALLA, Sreerupa; 3132 Arbor Drive, Shrewsbury, MA 01545 (US). Agent: GORDON, Dana, M. et al.; Foley Hoag LLP, Patent Group, Seaport West, 155 Seaport Blvd., Boston, MA 02210-2600 (US). = (74) = Designated States (unless otherwise indicated, for every (81) = kind of national protection available): AE, AG, AL, AM, = = AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, _ CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, = DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, = = MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, = = OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, = SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, — TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. = Designated States (unless otherwise indicated, for every (84) kind of regional protection available): ARIPO (BW, GH, = 1-1 GC 0 GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, 01 MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, M 1-1 0 --.... 00 1-1 (54) Title: COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF DISEASE 0 ei (57) : This invention relates to compounds and compositions for the induction of expression of a pattern recognition receptor 0 (e.g., STING) and methods of use thereof.