baber/WOPTO huggingface dataset:
Patent AU-2021295100-A1 (AU)
Title: Combination comprising an ADC or an AOC comprising a VHH, and a saponin or a ligand-saponin conjugate
Inventor: POSTEL RUBEN
IPC: A61K47/64
Filed: 2021-06-22
Abstract: The invention relates to a pharmaceutical combination comprising: a first conjugate comprising at least one effector molecule and a single-domain antibody (sdAb) for binding to a first cell-surface molecule; and comprising a saponin, a derivative thereof, or a second conjugate comprising a binding molecule for binding to a second cell-surface molecule on the same cell surface as the first cell-surface molecule and the saponin and/or the derivative thereof, wherein the saponin or the derivative thereof is a monodesmosidic or bidesmosidic triterpene glycoside. The invention also relates to a composition comprising the first conjugate and the saponin (derivative) or the second conjugate comprising the saponin (derivative). In addition, the invention relates to a pharmaceutical combination or composition of the invention, for use as a medicament, and for use in the treatment or the prophylaxis of a cancer, an auto-immune disease such as rheumatoid arthritis, an enzyme deficiency, a gene defect, a disease relating to a gene defect, an amyloidosis, a disease related to an enzyme deficiency, an infection such as a viral infection, hypercholesterolemia, primary hyperoxaluria, haemophilia A, haemophilia B, alpha- 1 antitrypsin related liver disease, acute hepatic porphyria, transthyretin-mediated amyloidosis. Furthermore, the invention relates to an in vitro or ex vivo method for transferring the first conjugate of the invention from outside a cell to inside said cell, preferably to the cytosol of said cell.
Patent AU-2021308879-A1 (AU)
Title: Dithiolene metal complexes
Inventor: REICHERT HANS
IPC: C07D239/22
Filed: 2021-07-09
Abstract: The present invention relates to particles of a compound of formula M (I), wherein M is selected from Ni, Pd and Pt, X
Patent AU-2021325923-A1 (AU)
Title: Crystalline forms of CFTR modulators
Inventor: IYEMPERUMAL SATISH KUMAR
IPC: C07C309/29
Filed: 2021-08-12
Abstract: Crystalline forms of salts of Compound I are disclosed. Pharmaceutical compositions comprising the same, methods of treating cystic fibrosis using the same, and methods for making the same are also disclosed.
Patent AU-2021349099-A1 (AU)
Title: Blood pump
Inventor: GRAUWINKEL MARIUS
IPC: A61M60/126
Filed: 2021-09-15
Abstract: This invention concerns an intravascular blood pump (1) for percutaneous insertion into a patient's blood vessel. The blood pump (1) comprises a pump casing (2) having a blood flow inlet (21) and a blood flow outlet (22), an impeller (3) arranged in said pump casing (2) so as to be rotatable about an axis of rotation (10). The impeller (3) has blades (31) sized and shaped for conveying blood from the blood flow inlet (21) to the blood flow outlet (22). The blood pump (1) comprises a drive unit (4) for rotating the impeller (3), the drive unit (4) comprising a magnetic core (400) including a plurality of posts (40) arranged about the axis of rotation (10) and a back plate (50) connecting the posts (40) and extending between the posts (40) in an intermediate area (59). A coil winding (44) is disposed around each of the posts (40). The coil windings (44) are controllable so as to create a rotating magnetic field, wherein the impeller (3) comprises a magnetic structure (32) arranged to interact with the rotating magnetic field so as to cause rotation of the impeller (3). A material of at least a portion of at least one of the posts (40) is integral with a material of the intermediate area (59) of the back plate (50). Further, the invention concerns a method of manufacturing a magnetic core (400) and a method of manufacturing an intravascular blood pump (1).
Patent AU-2021353860-A1 (AU)
Title: Carrier for containers
Inventor: MCCREE JUSTIN
IPC: B65D73/00
Filed: 2021-09-28
Abstract: A carrier for holding a plurality of containers includes a top panel comprising a plurality of container retention openings for at least partially receiving a respective container of the plurality of containers, at least one container retention flap foldably connected to the top panel, the top panel comprises at least one container retention tab positioned adjacent a respective container retention opening and foldably connected to the top panel at a respective fold line, at least one side reinforcement panel positioned between the top panel and the at least one container retention flap, and the top panel comprises at least one reinforcement portion extending from the respective fold line.
Patent AU-2021358962-A1 (AU)
Title: Microfluidic cell culture devices
Inventor: O'BOYLE DUNCAN A
IPC: B01L3/00
Filed: 2021-10-06
Abstract: Materials and methods of making have been developed for mass production of thermoplastic microfluidic chips. An elastomer diaphragm with a stress relieving feature can be used in microfluidic valves, pump diaphragms, and diaphragm micropumps. An optimized pump chamber design for complete fluid displacement and chamber geometry are provided. Microfluidic pressure regulators use a pneumatically actuated elastic membrane in a back-pressure regulator configuration. Microfluidic accumulators store pressurized fluid in a microfluidic chip. Removable caps for cell culture and a quick release top are described. Methods to incorporate hydrogels and ECM scaffolds have been developed. Electro pneumatic manifolds connect and control of multiple microfluidic devices vertically or on a rotary mechanism.
Patent AU-2021396163-A1 (AU)
Title: Device, method and system for reshaping a heart valve annulus
Inventor: CHILDS RICHARD T
IPC: A61B17/00
Filed: 2021-12-07
Abstract: Anchors for securing an implant within a body organ and/or reshaping a body organ are provided herein. Anchors are configured for deployment in a body lumen or vasculature of the patient that are curved or conformable to accommodate anatomy of the patient. The invention provides an implant system having multiple anchors, e.g., one or more posterior anchors in combination with one or more anterior anchors. Methods of deploying such anchors, and use of multiple anchors or multiple bridging elements are also provided.
Patent AU-2021403894-A1 (AU)
Title: Method and apparatus for preservation of biological material
Inventor: TAYLOR BRIAN
IPC: A01N1/02
Filed: 2021-12-17
Abstract: An apparatus for preserving biological material, comprising an insert configured to be arranged within an outer insulated tank, the insert defining a compartment for receiving biological material, such that, in operation, biological material in the compartment is immersed in the heat exchange fluid to exchange heat with the heat exchange fluid for freezing of said biological material, the apparatus further comprising a pump that is operable to adjust a flow of heat exchange fluid over the biological material in the compartment, the pump being operable to cool the biological material at one or more different stages of cooling.
Patent AU-2021413583-A1 (AU)
Title: Amorphous solid dispersion formulation
Inventor: YEN CHI-FENG
IPC: A61K31/5025
Filed: 2021-12-30
Abstract: Provided is an amorphous solid dispersion containing a Cap-dependent endonuclease inhibitor or a pharmaceutically acceptable salt thereof for oral administration, wherein the Cap-dependent endonuclease inhibitor or a pharmaceutically acceptable salt thereof is dispersed in a matrix formed from the pharmaceutically acceptable polymer. Further disclosed are methods for preparing a above amorphous solid dispersion and a use thereof for treating virus infection and a pharmaceutical composition containing same.
Patent AU-2021417003-A1 (AU)
Title: Massage apparatus
Inventor: SUTHERLAND ALEXANDER ADAM
IPC: A61H23/00
Filed: 2021-01-11
Abstract: An apparatus for use in massage comprises an extended structural support element, at least one massage member and two gripping members, which two gripping members are laterally disposed on the structural support element relative to one another. It is configured such that a user in a standing position with their arms at rest by their sides may grip the two gripping members, when the support structure is disposed behind them, and manipulate the apparatus to massage a position on their back. The apparatus enables a user to independently massage their back to relieve pain and/or tension or to relax, while maintaining a neutral body position and without inordinately straining or twisting any area of their body to impart a massaging force on their back.
Patent WO-2023023709-A1 (WO)
Title: Drinking fountain and fountain arm thereof
Inventor: ROBINSON NICHOLAS
IPC: E03B9/20
Filed: 2022-08-22
Abstract: A drinking fountain having an upwardly extending body in which is housed internal components of the fountain; and one or more fountain arms extending outwardly from the body via which water can be dispensed, wherein the or each arm is releasably fixable to the body between two or more positions to enable adjustment of a height of each fountain arm above the ground.
Patent AU-2022200695-A1 (AU)
Title: Compositions for controlled release of active ingredients and methods of making same
Inventor: PRESLAR ADAM TRUETT
IPC: A01N35/02
Filed: 2022-02-02
Abstract: Compositions for controlled release of active ingredients and methods of making same are generally 
provided. In some embodiments, the composition comprises an active ingredient and a delivery material. In 
some embodiments, the composition comprises a volatile or gaseous active ingredient useful for 
applications in at least one of agriculture, pest control, odor control, and food preservation. In some 
embodiments, the active ingredient is a cyclopropene. In some embodiments, the active ingredient is an 
essential oil, a terpene, or a terpenoid. In some embodiments, the delivery material is a carbon material or 
a silicate material.
Patent AU-2022200741-A1 (AU)
Title: Aminothiazole compounds as c-Kit inhibitors
Inventor: BENCIVENGA NICHOLAS E
IPC: A61P35/00
Filed: 2022-02-04
Abstract: The invention relates to c-Kit inhibitors useful in the treatment of cancers, and other 
serine-threonine kinase mediated diseases, having the Formula: 
(R 3)" 
R N 
1 2 L-A 
R2 
wherein A, L, R1, R2, R3, and n are described herein.
Patent AU-2022202106-A1 (AU)
Title: Low pressure carbon snow injector
Inventor: EMANUELLI MARCO
IPC: F25D3/10
Filed: 2022-03-29
Abstract: New low pressure carbon snow injector 
ABSTRACT 
5 
An equipment for making C02 snow, ready to be injected in an installation using 
such a snow, notably an installation of the food industry, equipment comprising a 
snow horn (7) and a J-Tube (2).  
10 
Figure 1
1/2 
10 
3 
Fig 1 
Fig. 2 a)
Patent AU-2022202415-A1 (AU)
Title: Multilayer self-adhesive fouling release film with textured surface
Inventor: PEROTTI DANIELE
IPC: B32B27/30
Filed: 2022-04-12
Abstract: SELF-ADHESIVE FOULING RELEASE FILM WITH TEXTURED SURFACE 
ABSTRACT 
5 The invention concerns a multilayer self-adhesive fouling release film with textured 
surface (1) provided with a surface morphology comprising a regular or randomly 
distributed pattern of ribs (3).  
The invention also concerns a method for producing a multilayer self-adhesive 
10 fouling release film with textured surface (1) provided with a surface morphology 
comprising a regular or randomly distributed pattern of ribs (3), a use of the method 
for producing a multilayer self-adhesive fouling release film with textured surface 
(1) according to the invention and a method for producing a coated substrate.
Patent AU-2022203543-A1 (AU)
Title: Methods of treating inflammation or neuropathic pain
Inventor: BLANKMAN JACQUELINE LORAYNE
IPC: C07D403/10
Filed: 2022-05-25
Abstract: Provided herein are methods of treating inflammation or neuropathic pain using an effective dose 
of a monoacylglycerol lipase inhibitor or a composition thereof.
Patent AU-2022203799-A1 (AU)
Title: Techniques for classification with neural networks
Inventor: GURUMURTHY PRAKASH
IPC: G06N3/04
Filed: 2022-06-02
Abstract: OF DISCLOSURE 
Apparatuses, systems, and techniques to train neural networks to perform classification.  
In at least one embodiment, one or more neural networks are trained to perform classification 
based, at least in part, on grouping one or more sets of neural network training data according to 
behaviors of one or more objects within one or more images represented by the training data.  
208
Sheet 5/56 
500 
4) 
Grouping one or more sets of neural network training 
data 
502 
Assigning one or more labels to a corresponding one 
or more clusters into which the neural network 504 
training data is grouped 
Training one or more neural networks using the 
neural network training data and the one or more 506 
labels 
Performing Other Actions 508 
FIG. 5
Patent AU-2022209365-A1 (AU)
Title: Systems and methods for biomolecule preparation
Inventor: KAPP GREGORY
IPC: G01N33/543
Filed: 2022-01-21
Abstract: Methods for the preparation of sample polypeptide fractions are described. Sample polypeptides may be isolated from any of a variety of sources, including biological and non-biological systems. Sample polypeptides may be coupled or conjugated to other molecules to permit characterization of the sample polypeptide fractions. Sample polypeptide fractions may be prepared for analysis by a polypeptide assay.
Patent AU-2022226014-A1 (AU)
Title: Underwater concrete block structure and construction method therefor
Inventor: KIM SANGKI
IPC: E02D25/00
Filed: 2022-02-11
Abstract: The present invention suggests a method for constructing an underwater concrete block structure through a first concrete block manufacturing step, a guide pole installation step, a first concrete block installation step, a second concrete block manufacturing step, a second concrete block installation step, a draining step, a guide pole removal step, and a concrete column forming step, and accordingly, a concrete column and a first concrete block can be firmly coupled to each other via a reinforcing bar assembly for a column.
Patent AU-2022228407-A1 (AU)
Title: Waterway integration device
Inventor: ZHOU ZHAOTAO
IPC: F25D23/12
Filed: 2022-03-01
Abstract: Disclosed in the present invention is a waterway integration device, mounted in a body of a refrigeration appliance. The waterway integration device comprises a filter, a water valve, and a water container which are communicated with each other; a water inlet pipe is provided on the filter; a water container outlet pipe is provided on the water container; an ice-making water supply pipe is provided on the water valve; the rear wall of the body is provided with a through hole which is communicated with the outside of a refrigerator, and a water pipe mounting structure; the water pipe mounting structure comprises a pre-buried pipe provided in the through hole and a protection pipe provided in the pre-buried pipe; the protection pipe is provided with at least three water pipe holes corresponding to the water inlet pipe, the water container outlet pipe, and the ice-making water supply pipe. According to the waterway integration device in the present invention, the water pipes on the filter, the water container, and the water valve pass through the protection pipe, and the protection pipe is matched with the pre-buried pipe, so that a plurality of water pipes are disposed in different water pipe holes of the protection pipe respectively; thus, the water pipes can be arranged; moreover, the protection pipe is arranged between the pre-buried pipe and the water pipes, and thus, a sealing effect can be achieved, thereby preventing cold air in the body from leaking to the outside.
Patent AU-2022241988-A1 (AU)
Title: Vmat2 inhibitors and methods of use
Inventor: HARRIOTT NICOLE
IPC: C07D471/04
Filed: 2022-03-21
Abstract: This disclosure relates generally to VMAT2 inhibitor compounds of formula (I), compositions, and methods related thereto.
Patent AU-2022246448-A1 (AU)
Title: Systems and methods for playback device management
Inventor: SOTO KURT THOMAS
IPC: H04R27/00
Filed: 2022-10-07
Abstract: Systems and Methods for Playback Device Management 
Abstract 
Systems and methods for managing playback devices in accordance with embodiments of the 
invention are illustrated. One embodiment includes a method for modifying a system that includes 
several devices. The method includes steps for measuring a first signal pattern for wireless signals 
between the several devices, measuring a second signal pattern for the wireless signals after measuring 
the first signal pattern between the several devices, determining an updated state of the system based 
on a difference between the second signal pattern and the first signal pattern, and modifying state 
variables of one or more devices of the playback system based on the determined updated state.
Patent AU-2022253700-A1 (AU)
Title: System for cleaning milk ducts for a machine for preparing beverages
Inventor: CARBONINI CARLO
IPC: A47J31/60
Filed: 2022-04-06
Abstract: Cleaning system for a machine (M) for preparing beverages, comprising a washing water supply piping (40; 40') and a washing chamber (48) which may be supplied with washing water provided by the washing water supply piping (40), it being possible to place the movable part of a flexible hose (51) that has been extracted from a milk reservoir (T) into the washing chamber, wherein, through the flexible hose (51), the washing water contained in the washing chamber (48) may be conveyed to a frothing head (31) of the machine (M), and wherein the washing chamber (48) is formed in a tray (60'') which may be coupled in a releasable manner to the body of the machine (M) under the frothing head (31), a collection chamber (72'') also being formed in the tray, which collection chamber is separate from the washing chamber (48) and configured to be arranged under the distribution duct (33) of the frothing head (31).
Patent AU-2022259875-A1 (AU)
Title: System and method for cathodic protection monitoring
Inventor: DA COSTA ANTONIO
IPC: G01R31/00
Filed: 2022-04-20
Abstract: The system and method of the present application improve pipeline integrity and may optimize operational efficiencies. Using the data that is generated by cathodic protection and pipeline integrity monitoring devices (e.g. rectifier monitoring), the present application utilizes data analytics techniques, such as artificial intelligence and machine learning algorithms, to improve pipeline integrity operations.
Patent AU-2022265022-A1 (AU)
Title: Three-dimensional ultrasonic imaging method and system based on laser radar
Inventor: ZHENG YONGPING
IPC: G01S17/89
Filed: 2022-04-27
Abstract: A three-dimensional ultrasonic imaging method and system based on a laser radar. The system comprises: an ultrasonic probe (10), used for performing ultrasonic scanning on a region of interest of a target object; a two-dimensional ultrasonic imaging device (15), used for generating a two-dimensional ultrasound image of the region of interest of the target object on the basis of ultrasound scanning; a three-dimensional space information acquisition device (12), used for acquiring three-dimensional space information of the ultrasonic probe (10) by means of the laser radar (13); a three-dimensional reconstruction module (16), used for reconstructing a three-dimensional ultrasound image on the basis of the three-dimensional space information of the ultrasonic probe (10) and the two-dimensional ultrasound image; and a user terminal (20), used for displaying the three-dimensional ultrasound image. The system reconstructs the three-dimensional ultrasound image in a flexible, low-cost and small-size manner, thereby improving accessibility of the three-dimensional ultrasonic technology, and expanding application scenarios in the field of three-dimensional sensing.
Patent AU-2022271400-A1 (AU)
Title: A tooth anti-staining composition, kit and method of using the same
Inventor: LEE CHUNG-LIN
IPC: A61K8/87
Filed: 2022-11-15
Abstract: The present disclosure relates to a tooth anti-staining composition comprising 
polyurethane and dicalcium phosphate and optionally other orally acceptable carriers 
and/or excipients. The present disclosure also provides a tooth anti-staining kit and a 
tooth anti-staining method with the tooth anti-staining composition.
Patent AU-2022312308-A1 (AU)
Title: Method for managing quality of specific cells, and method for manufacturing specific cells
Inventor: NAKAMURA KENTARO
IPC: C12Q1/02
Filed: 2022-07-14
Abstract: The purpose of the present invention is to provide a quality management method for managing the quality of cells with which it is possible to select cells having medicinal properties, and a method for manufacturing cells in which the above quality management method is used. The present invention provides a quality management method for managing the quality of specific cells, the method including: evaluating the correlation between an expression pattern for an associated gene cluster characteristic of the specific cells, obtained by measuring the state of expression of the gene cluster, and an expression pattern serving as a reference; and if the correlation is of a given degree or greater, determining that the cells are usable.
Patent AU-2023200204-A1 (AU)
Title: Adjustable random electrical stimulation technologies
Inventor: SCHEPIS ERIC A
IPC: A61N1/32
Filed: 2023-01-16
Abstract: A method of providing therapy to a patient according to one embodiment includes 
partitioning a frequency range into a plurality of discrete frequency bands with each having a 
corresponding bandwidth, generating a composite electrical signal based on a plurality of 
periodic signals, wherein each periodic signal has a frequency within a corresponding frequency 
band of the plurality of discrete frequency bands, delivering the composite electrical signal 
through one or more electrodes to the patient to target at least one of neural tissue or non-neural 
tissue of the patient, adjusting an amplitude of one or more of a voltage or a current of the 
composite electrical signal within a selected frequency band of the plurality of discrete frequency 
bands to generate an adjusted signal based on feedback received from the patient, and delivering 
the adjusted electrical signal through the one or more electrodes to provide therapy to the patient.  
1004496002
1/16 
50 
134 
135 
107-1 
116 
108 
S 109 
117 
FIG. 1
Patent AU-2023206155-A1 (AU)
Title: Additive manufacturing support material
Inventor: HUDSON ANDREW
IPC: B01J13/06
Filed: 2023-07-19
Abstract: This document describes a process of producing gel microparticles, which are 
consistent in size and morphology. Through the process of coacervation, large 
volumes of gel microparticle slurry can be produced by scaling up reactor vessel size.  
Particles can be repeatedly dehydrated and rehydrated in accordance to their 
environment, allowing for the storage of particles in a non-solvent such as ethanol.  
Gel slurries exhibit a Bingham plastic behavior in which the slurry behaves as a solid 
at shear stresses that are below a critical value. Upon reaching the critical shear stress, 
the slurry undergoes a rapid decrease in viscosity and behaves as a liquid. The 
rheological behavior of these slurries can be adjusted by changing the compaction 
processes such as centrifugation force to alter the yield-stress. The narrower 
distribution and reduced size of these particles allows for an increase in FRESH 
printing fidelity.