baber/WOPTO huggingface dataset:
Patent ID-25789-A (ID)
Inventor: BERG STEFAN
IPC: A61P25/28
Filed: 1998-09-09
Abstract: PCT No. PCT/SE98/01602 Sec. 371 Date Oct. 21, 1998 Sec. 102(e) Date Oct. 21, 1998 PCT Filed Sep. 9, 1998 PCT Pub. No. WO99/13878 PCT Pub. Date Mar. 25, 1999The invention relates to a combination of a first component (a) which is a monoamine oxidase inhibitor and a second component (b) which is selective h5-HT1B antagonist or partial agonist having the formula I wherein X is CH2, O; Y is CONH, NHCO; R1 is H, C1-C6 alkyl, C3-C6 cycloalkyl; R2 is H, C1-C6 alkyl, C1-C6 alkoxy, halogen; R3 is R4 and R5 independently are H or C1-C4 alkyl, as racemate, R-enantiomer or S-enantiomer, and said components (a) and (b) being in the form of free bases, solvates or pharmaceutically acceptable salts thereof, the preparation thereof, pharmaceutical formulations containing said combination, use of and method of treatment of affective disorders such as depression, anxiety and OCD with said combination as well as a kit containing said combination.
Patent IL-101082-A (IL)
Title: Process for converting trans-n-methyl-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthaleneamine to cis-n-methyl-4- (3,4-di- chlorophenyl)-1,2,3,4- tetrahydro-1- naphthaleneamine
IPC: C07C211/42
Filed: 1992-02-27
Abstract: A novel process for converting trans-isomeric N-methyl-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthaleneamine to cis-isomeric N-methyl-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthaleneamine is disclosed. The process involves contacting trans-isomeric N-methyl-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthaleneamine, or a mixture of same with up to about an equal part by weight of the corresponding cis-isomer, with a basic equilibration agent like potassium tert.-butoxide in a reaction-inert polar organic solvent to ultimately afford a cis/trans-mixture wherein the amount of cis-amine present in said mixture achieves a constant value of about 2:1 on a weight-by-weight basis. The aforesaid resultant mixture is useful as an intermediate product that ultimately leads to pure cis-(1S) (4S)-N-methyl-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenea mine (sertraline), which is a known antidepressant agent.
Patent IL-102856-A (IL)
Title: Crystalline form of (r)-3-methoxy-4-[1-methyl-5-(2-methyl-4,4,4-trifluoro butyl carbamoyl) indol-3-ylmethyl]-n-(2-methylphenyl-sulphonyl) benzamide process for its preparation and pharmaceutical compositions containing it
IPC: A61P9/00
Filed: 1992-08-18
Abstract: A physical form of (R)-3-methoxy-4-[1-methyl-5-(2-methyl-4,4,4-trifluorobutylcarbamoyl)in dol-3-ylmethyl]-N-(2-methylphenyl-sulphonyl)benzamide substantially free of other physical forms, which form is crystalline and has an X-ray powder diffraction pattern with specific peaks at 2 THETA  = 14.0, 19.4, 22.0, 22.4 and 24.7 DEG , processes for preparing the form and pharmaceutical compositions containing it. The compound is a leukotriene antagonist useful in the treatment of diseases such as asthma.
Patent IL-105623-A (IL)
Title: Oxazaborolidine catalysts for the enantioselective reduction of prochiral ketones
IPC: C07C35/32
Filed: 1993-05-06
Abstract: The borane reduction of prochiral ketones to optically pure alcohols is effectively achieved by the utilization of catalytic amounts of the new and valuable oxazaborolidine catalysts of formula (I).
[WO9323408A1]
Patent IL-114310-A (IL)
Title: Fibered coils
IPC: A61B17/12
Filed: 1995-06-25
Abstract: This invention is a vasoocclusive device. It is placed in the vasculature of an animal to form thrombus in a selected site such as an aneurysm or AVM. The device uses a central coil having thrombogenic fibers placed on the coil in a specified fashion. The coil will pass through the lumen of a vascular catheter and form a convolution when ejected from the catheter's distal end. The fibers are attached to the coil and cooperate with the coil so that upon ejection from the catheter, the convoluted coil forms a shape in which the central region contains the majority of these fibers.
Patent IL-114798-A (IL)
Title: Preparation of o-(2-hydroxyalkyl) oxime
IPC: C07C251/54
Filed: 1995-08-01
Abstract: PCT No. PCT/EP95/02932 Sec. 371 Date Feb. 3, 1997 Sec. 102(e) Date Feb. 3, 1997 PCT Filed Jul. 25, 1995 PCT Pub. No. WO96/04237 PCT Pub. Date Feb. 15, 1996Preparation of O-(2-hydroxyalkyl)oximes I    <IMAGE>  (I)  (R1 and R2=alkyl or R1 and R2 and the C atom which carries them=5- to 7-membered cycloalkyl), by catalytically hydrogenating an O-(2,3-epoxyalkyl)oxime of the general formula II    <IMAGE>  (II)  using hydrogen. The products I are suitable as intermediates for herbicides.
Patent IL-115467-A (IL)
Title: Stackable block system
IPC: A63H33/08
Filed: 1995-09-29
Abstract: PCT No. PCT/DK95/00389 Sec. 371 Date Jun. 9, 1997 Sec. 102(e) Date Jun. 9, 1997 PCT Filed Sep. 28, 1995 PCT Pub. No. WO96/09870 PCT Pub. Date Apr. 4, 1996A stacking block system having stacking blocks which have a body part which is provided with coupling knobs with a mutual uniform modular distance on its upper surface and is downwardly provided with coupling means which are complementary with respect to the coupling knobs on the upper side and are adapted to be coupled with the coupling knobs. According to the invention, the blocks are additionally provided with one or more spacers downwardly, which are designed such that when two stacking blocks are stacked on top of each other, the body parts of the stacking blocks will be spaced from each other along their entire periphery. This provides a gripping edge or a gap between two blocks stacked so that it is particularly easy to grip the blocks when a stack of such blocks is to be separated.
Patent IL-122407-A (IL)
Title: Microorganism containing a plasmid encoding the herpes simplex virus thymidine kinase gene, uses thereof and pharmaceutical compositions containing it
IPC: C12N1/21
Filed: 1996-06-05
Abstract: The present invention is directed to the isolation and use of super-infective, tumor-specific vectors that are strains of parasites including, but not limited to bacteria, fungi and protists. In certain embodiments the parasites include, but are not limited to, the bacterium Salmonella spp., such as Salmonella typhimurium, the bacterium Mycobacterium avium and the protozoan Leishmania amazonensis. In other embodiments, the present invention is concerned with the isolation of super-infective, tumor-specific, suicide gene-containing strains of parasites for use in treatment of solid tumors.
Patent IL-130446-A (IL)
Title: Parcels comprising at least two stacks of units of goods and means, method and apparatus for forming said parcels
IPC: B63B/
Filed: 1997-12-18
Abstract: Parcel comprising at least one pair of stacks (A,B) of units of goods surrounded by a self-clamping load sling in the form of a closed loop with overlapping ends secured permanently together comprising a central suspension loop (14) extending upwards between said stacks, and through a central opening in the upper part of the sling, characterized in that the sling is in the form of a belt (2) and having a width substantially equal to the transverse width of said stacks (A, B) and where the central loop is gathered together to form a lifting eye (15) and that the belt ends are secured permanently together by sewing, gluing, or hot melt. 477 כ" ו באדר התשס" ב - March 10, 2002
Patent IL-131478-A (IL)
Title: Uses of streptolysin o in the preparation of medicaments adapted to treat scar tissue
IPC: A61K38/00
Filed: 1999-08-18
Abstract: Methods are presented for treatment in eliminating or reducing the appearance of scar tissue by administration of streptolysin O.
Patent IL-137471-A (IL)
Title: Watermark applied to one-dimensional data
IPC: G10L25/51
Filed: 1998-04-01
Abstract: In the process of embedding watermark information in one-dimensional source data, first spread one-dimensional data x(t) is generated by subjecting one-dimensional source data s(t) to spectrum-spreading operation using a PN sequence g(t). This first spread one-dimensional data x(t) then undergoes a modified discrete cosine transformation. A specific frequency component value of the MDCT coefficients is modulated to provide association with the watermark information. The modulated frequency component then undergoes inverse transformation to generate second spread one-dimensional data x'(t). Then, using the same PN sequence in the spreading, the second spread one-dimensional data is subjected to spectrum-despreading to produce digitally watermarked one-dimensional data in which watermark data has been embedded. <IMAGE>
Patent IL-151200-A (IL)
Title: Tricyclic imidazopyridine prodrug derivatives and pharmaceutical compositions containing the same
IPC: C07D471/14
Filed: 2002-08-12
Abstract: Compounds of formula 1, in which the substituents have the meanings mentioned in the description are suitable for the prevention and treatment of gastrointestinal diseases.
Patent IL-174471-A (IL)
Title: Methods for synthesizing quinolinone compounds and compositions comprising such compounds
IPC: C07D409/14
Filed: 2006-03-22
Abstract: A method of synthesizing a substituted or unsubstituted 4-amino-3-benzimidazolyl quinolinone compound includes reacting a first compound having the formula I with a second compound having the formula II in a suitable solvent in the presence of a sodium or potassium salt of a base. The first compound and the second compound have the following structures where the variables have the values described herein:
Patent IL-194516-A (IL)
Title: 3,7-diamino-10h-phenothiazine salts and their use
Filed: 2008-10-02
Abstract: Described are methods of preparing reduced 3,7-diamino-10H-phenothiazine (DAPTZ) compounds of formula:wherein: R1 and R9 are independently selected from: —H; C1-4alkyl; C2-4alkenyl; and halogenated C1-4alkyl; each of R3NA and R3NB is independently selected from: —H; C1-4alkyl; C2-4alkenyl; and halogenated C1-4alkyl; each of R7NA and R7NB is independently selected from: —H; C1-4alkyl; C2-4alkenyl; and halogenated C1-4alkyl; each of HX1 and HX2 is independently a protic acid; and pharmaceutically acceptable salts, solvates, and hydrates thereof. These methods are particularly useful for producing stable reduced forms, and with high purity. The stability and purity are especially relevant for pharmaceutical compositions for the treatment of disease. The compounds are useful for treatment of e.g. tauopathies, such as Alzheimer's disease, and also as prodrugs for the corresponding oxidized thioninium drugs.
Patent IL-200173-A (IL)
Title: Use of sodium meta arsenite in the manufacture of an oral dosage form of a pharmaceutical composition for the treatment of non-cancer associated inflammation in a mammal and a kit comprising same
IPC: A61P/
Filed: 2009-07-30
Abstract: The present invention relates to the use of arsenic compounds such as sodium meta arsenite (NaAsO2), arsenic trioxide (As2O3), and arsenic hexoxide (As4O6) or combinations thereof, for the treatment of painful, hyperalgesic and/or inflammatory conditions. The present invention also relates to compositions containing the above arsenic compounds for use in the treatment of pain, inflammation and immunological and autoimmune diseases and disorders.
Patent IL-205029-A (IL)
Title: (r)-4-(heteroaryl) phenylpropionic derivatives and pharmaceutical compositions containing them
IPC: C07D/
Filed: 2010-04-12
Abstract: The present invention relates to a novel class of (R)-4-(heteroaryl)phenylpropionic derivatives of formula (I), useful in the inhibition of the chemotactic activation induced by the fraction C5a of complement. Said compounds are useful in the treatment of pathologies depending on the chemotactic activation of neutrophils and monocytes induced by the fraction C5a of the complement. In particular, the compounds of the invention are useful in the treatment of autoimmune hemolytic anemia (AIHA), psoriasis, bullous pemphigoid, rheumatoid arthritis, ulcerative colitis, acute respiratory distress syndrome, idiopathic fibrosis, glomerulonephritis and in the prevention and treatment of injury caused by ischemia and reperfusion.
Patent IL-211114-A (IL)
Title: Pharmaceutical composition comprising 3 alpha-hydroxy-3-beta methoxymethyl- 21-(1'-imidazolyl)-5α-pregnan-20-one for use in the treatment of obsessive compulsive disorder, post-traumatic stress disorder or social anxiety disorder
IPC: A61K/
Filed: 2011-02-08
Abstract: The present invention relates to a pharmaceutical composition, comprising 3±-hydroxy-3²-methoxymethyl-21-(1'-imidazolyl)-5a-pregnan-20-one or a pharmaceutically-acceptable salt or solvate thereof, and one or more pharmaceutically-acceptable excipients, wherein the composition provides steady state plasma levels of 3±-hydroxy-3²-methoxymethyl-21-(1'-imidazolyl)-5±-pregnan-20-one in a range of from 5 ng/mL to 500 ng/mL for a duration of from 6 h to 24 h following administration.
Patent IN-2014KO00043-A (IN)
Inventor: SHIVAPRASAD MANJULA TARIKERE
IPC: A61K36/00
Filed: 2014-01-10
Abstract: A cosmetic composition comprising aqueous extracts of Tecomellaundulata and Cephalandraindica; and cosmetically acceptable excipients; wherein said extracts are present in a ratio of about 1:1. Thecombination of extracts present in an amount of 10 ppm to 1000 ppmprovides enhanced collagen induction and enhanced protection against free radicals. Also provided is the process for preparation of the said cosmetic composition.
Patent JP-S5224116-A (JP)
Title: Material of high magnetic flux density one directionally orientated el ectromagnetic steel and its treating method
Inventor: TAKASHIMA KUNIHIDE
IPC: C22C38/00
Filed: 1975-08-20
Abstract: PURPOSE: To gain material of high megnetic flux density one directionally orientated electromagnetic steel, having stable superior property even treated with low temperature slab heat at 1100W1260°C, by adding nitride formation element to normal silicon steel material at steel making. 
     COPYRIGHT: (C)1977,JPO&Japio
Patent JP-S62258240-A (JP)
Title: V-belt
Inventor: MORIMOTO YOSHIRO
IPC: F16G5/18
Filed: 1986-04-30
Abstract: PURPOSE:To ensure the strength of chains and reduce the amplitude to reduce the noise, by arranging a plurality of rows of chains in parallel with pin positions shifted in a pitch direction, and thereby shifting the phase of chord vibration so as to reduce the amplitude. CONSTITUTION:Pin positions of both chains 3 and 4 are shifted half a pitch to generate a shift in phase of chord vibration and thereby reduce an amplitude  L in radial link displacement through link plates 31 and 41 and load blocks 5. That is, while a first pin 321 of the chain 3 moves radially away from the center O, second pins 420 and 421 located at the front and rear positions of the pin 321 operate to move the pin 321 toward the center O. On the other hand, the pins 321 and 322 similarly operate to move the pin 421. Thus, a polygon is formed by pitch lines Pl having a pitch of 1/2l with an inscribed circle defined by a running locus D of a V-belt A. Accordingly, although the chains 3 and 4 have a pitch of l, they develop the chord vibration having a pitch of 1/2l, thus simultaneously achieving the insurance of strength and the reduction in noise upon contact meshing with pulleys 1 and 2.
Patent JP-S62257280-A (JP)
Title: White level follower circuit
Inventor: YAMAZAKI NOBUHISA
IPC: H04N1/407
Filed: 1986-04-30
Abstract: PURPOSE:To improve the overall operating speed by making the motion period of the recording mode and the follow-up mode longer than that of the freezing mode. CONSTITUTION:In a period switching circuit 11, a line counter 12 outputs line signals representing an even-number line and an odd-number line based on a clock, and a timing generating circuit 13 generates a timing clock corresponding to the operational mode in response to the inputting of a mode signal. A timing clock (b) in the freezing mode makes an address register 4 able to be updated by the sequential output of an address counter 3 at each bit, so that the sequential addresses of a white level memory 5 are accessed, and white level values are read out to a white level register 6. Timing clocks in the recording mode and the follow-up mode have a period of a length double that of the timing clock (b), to execute the recording/follow-up motion of one-line-share of bits by two sequential lines.
Patent JP-S62257140-A (JP)
Title: Back projection screen
Inventor: TAKAHASHI HIDEO
IPC: G03B21/625
Filed: 1986-04-30
Abstract: PURPOSE:To obtain a uniform and bright screen by providing a group of many prisms on an incidence surface and drawing a vertical locus which contains an outward convex surface on an observation-side surface. CONSTITUTION:A back projection screen S is formed by arraying the group of horizontally extending arcuate prisms 1 concentrically. The group of prisms 1 are in an outward convex arc shape and becomes inverted when projected slantingly above. In this case, a light source for projection such as a CRT is denoted as P and the center of the arc on a plane containing the screen S is denoted as O'. Then when the segment O' P is perpendicular to the plane F, respective points on the same arc are all at equal distance from the light source P, so angles of projection on prism sections of prisms 1 become equal by equalizing the sections on the arc, thereby realizing the well balanced screen S which is easily designed while not only vertical light, but also horizontal light are restricted.
Patent JP-S63265951-A (JP)
Title: Aromatic polyester resin composition
Inventor: SUGIMOTO HIROAKI
IPC: C08L67/02
Filed: 1987-04-22
Abstract: PURPOSE:To obtain the title composition excellent in moldability and heat resistance and giving a molding of excellent quality, by mixing an aromatic polyester having a main chain mainly consisting of structural units derived from an aromatic compound with at least either of two specified stabilizers. CONSTITUTION:At least one monomer selected from among an aromatic dicarboxylic acid, an aromatic diphenol and an aromatic hydroxycarboxylic acid is polycondensed to obtain an aromatic polyester (A) mainly consisting of at least one kind of structural units of formulas I-III (wherein Ar, Ar' and Ar'' are each a bivalent aromatic group) and having a flow temperature of 200-400 deg.C. 100pts.wt. component A is mixed with 0.03-8pts.wt. stabilizers (B) of formulas IV and/or V (wherein R1 is a 1-5C alkylene or alkylidene, R2 is a 1-6C alkyl, a 6-8C aryl, M is Ni or Ca, R3-4 are each a tert. alkyl and X is an amine compound).
Patent JP-H07283156-A (JP)
Title: Thermal diffusion process wafer support boat
Inventor: TSUCHIYA ISAMU
IPC: H01L21/324
Filed: 1994-04-13
Abstract: PURPOSE:To provide a wafer support boat which is capable of keeping a wafer free from crystal defects in a thermal diffusion process. CONSTITUTION:A thermal diffusion processing wafer support boat 10 of quartz glass provided in a horizontal thermal diffusion oven where reaction gas flows is equipped with wafer supporting grooves 12 provided at a prescribed interval in the lengthwise direction of the oven so as to support wafers 16 disposed side by side vertical to a flow of reaction gas excluding reinforcing parts 13 and 14 (at least one of them is provided). Therefore, dummy wafers 16a of the same shape with the wafer 16 are placed in wafer supporting grooves 12a and 12b located at lengthwise ends and other wafer supporting grooves 12c, 12d, 12e, 12f, 12g, and 12h out of the wafer supporting grooves adjacent to the reinforcing parts 13 and 14.
Patent JP-H11276272-A (JP)
Title: Panel
Inventor: KOURA HARUO
IPC: A47B77/06
Filed: 1998-03-27
Abstract: PROBLEM TO BE SOLVED: To make a panel body to be freely attached/detached to make work easier by attaching connecting terminals of piping and wiring set in a wall of the panel body so as to block the opening part on the panel. SOLUTION: A kitchen cabinet 2 is set on a sink cabinet, etc., in a room 1 and this panel 4 is attached together with a bedding plate of a vertical wall 3, on which the back face or the side face 2b of the kitchen cabinet 2 abuts, of the room 1 onto a pillar. Further, an opening is equipped on a position to be attached with connection terminals of piping and wiring on the surface of the panel 4 and a panel body 6 is detachably attached by screws to the panel 4 so as to block the opening. The material for the panel body 6 is to be equal to that of the panel 4. A faucet 8, a gas cock 9, and a power outlet 10, which are connection terminals of piping and wiring in the vertical wall 3, are made so as to be attached to the panel body 6.
Patent JP-S5625434-A (JP)
Title: Preparation of foamed body of phenolic resin
Inventor: YOSHIMI NAOKI
IPC: C08J9/04
Filed: 1979-08-08
Abstract: PURPOSE: To obtain a foamed body having uniform and minute foam particles by adding a surfactant, polyvinyl alcohol and alkaline-earth metals to the phase of resin after neutralizing the product of reaction between phenolic and aldehyde substances.  
     CONSTITUTION: After the product of reaction between phenolic and aldehyde substances being neutralized, a water phase is separated and removed from a resin phase. Next, to the resin phase are added a surfactant, polyvinyl alcohol and alkaline-earth metals or the oxide or hydroxide of zinc, being heated and dehydrated. To this are added a foaming agent and a hardening agent and, after mixing and blending, the substance thus produced is heated, foamed and hardened, thus a foamed body being prepared. As the surfactant, a silicone nonionic activator or the like is used, which is added in 0.5W3pts. to about 100pts. of phenolic substance. As for polyvinyl alcohol, 0.05W1pt. thereof is added to about 100pts. of phenolic substance. 
     COPYRIGHT: (C)1981,JPO&Japio
Patent JP-S583942-A (JP)
Title: Ni alloy with superior embrittlement resistance at intermediate temperature
Inventor: YOSHIDA TAKESHI
IPC: C22C19/05
Filed: 1981-06-29
Abstract: PURPOSE:To enhance the embrittlement resistance of an Ni-Mo alloy at intermediate temp. without deteriorating the resistance to hydrochloric acid by adding a very small smount of B to the alloy and restricting the contents of the inevitable impurities. CONSTITUTION:An Ni alloy with superior embrittlement resistance at intermediate temp. as well as high weldability and corrosion resistance is obtd. by providing a composition consisting of, by weight, 26-30% Mo, 0.01-2.0% Fe, 0.001-0.01% B and the balance Ni with inevitable impurities and by restricting the contents of Cr, Mn, Co, Si, C, P and S as the impurities to <=1.0% Cr, <=1.0% Mn, <=1.0% Co, <=0.1% Si, <=0.02% C, <=0.04% P and <=0.03% S. The Ni alloy does not cause annealing cracking when it passes through the temp. range of about 700-800 deg.C during annealing after cold working or welding.
Patent JP-S61259072-A (JP)
Inventor: SAITO MASARU
IPC: F25D23/08
Filed: 1985-05-13
Abstract: (57)【要約】本公報は電子出願前の出願データであるた め要約のデータは記録されません。