baber/WOPTO huggingface dataset:
Patent NZ-238636-A (NZ)
Title: Araliphatically n-substituted aminoalkanephosphinic and phosphonic acid derivatives and pharmaceutical compositions thereof
Inventor: MARESCAUX CHRISTIAN
IPC: A61P25/10
Filed: 1991-06-20
Abstract: Compounds having GABAB-antagonistic properties, for example those of formula I    <IMAGE>  (I)  wherein one of the radicals R1, R2 and R3 is hydrogen or an aliphatic, cycloaliphatic, araliphatic or aromatic radical, another is hydrogen or, in the case of R1 or R2, hydroxy or, in the case of R1, halogen or, in the case of R2 together with R2', oxo, and the remaining radical is hydrogen, R1' is hydrogen or halogen, R2' is hydrogen, hydroxy or, together with R2, is oxo, R4 and R5 are hydrogen or R4 is an araliphatic or heteroarylaliphatic radical and R5 is hydrogen or an aliphatic radical, and R is an aliphatic, cycloaliphatic, cycloaliphatic-aliphatic, araliphatic, heteroarylaliphatic or aromatic radical having at least 2 carbon atoms or, when R1 is hydrogen or hydroxy, R2 is an aromatic radical and R1', R2' and R3 are hydrogen, R is methyl, and their pharmaceutically acceptable salts, can be used as active ingredients in medicaments for the treatment of epilepsies of the "petit mal"  type. The invention relates also to novel compounds of formula I and processes for the preparation thereof.
Patent NZ-238832-A (NZ)
Title: Pastas prepared from a mixture containing 5 to 20 parts of a flavouring composition
Inventor: HAUSER THOMAS WILHELM
IPC: A23L7/109
Filed: 1991-07-04
Abstract: In order to prepare flavoured pasta presented in dry form, a mixture is prepared comprising a starchy-food ground product, a starch, an emulsifier, a gelling agent and a flavouring composition, the pasta is shaped by cooking/extrusion, the pasta is placed in contact with an aqueous calcium solution and the pasta obtained is dried.
Patent NZ-258931-A (NZ)
Title: Tube and manufacture thereof comprising crumpling, crushing and welding neck folds
Inventor: REBEYROLLE MICHEL
IPC: B65D35/12
Filed: 1993-12-15
Abstract: The invention disclosure relates to a process for manufacturing a collapsible tube with a wall containing more than 60% by volume of plastic material from a substantially cylindrical, or tubular, blank. The inside and outside layers of the tubular blank are of polymeric plastic material, and the tube has a skirt and a necked head. In the process a shaping operation is performed where an end portion of the tubular blank is necked by bringing closer together inner and outer tools, thus producing crumpled folding of the end of the tube. Prior to the shaping operation the blank is heated in order to bring the portion of the end portion to be shaped to a temperature at the time of the shaping operation which is at least equal to the melting point of the polymeric plastic material forming of the layers the inside and outside surfaces of the wall of the blank. The polymeric plastic material is thus in a viscous molten state at the time of the shaping operation. By virtue of the shaping operation, the crumpled folds are formed by simply bringing closer together the inner and outer tools so that when the folds are fully crushed between the tools and the folds are completely welded to each other, thereby producing the necked head and shoulder integral with the remaining skirt portion of the previously tubular blank.
Patent NZ-262663-A (NZ)
Title: Method for amplifying dna sequences, modified dna polymerase, formulations of dna polymerases
Inventor: BARNES WAYNE M
IPC: C12Q1/686
Filed: 1994-02-22
Abstract: A DNA polymerase having an amino acid sequence comprising substantially the same amino acid sequence as that of Thermus aquaticus or Thermus flavus DNA polymerase, excluding the N-terminal 280 amino acid residues of Thermus aquaticus DNA polymerase or the N-terminal 279 amino acid residues of Thermus flavus DNA polymerase, recombinant DNA sequences encoding said DNA polymerases, vectors comprising said DNA sequences, and host cells containing such vectors. A formulation of thermostable DNA polymerases comprising a majority component comprised of at least one thermostable DNA polymerase of the type described above, wherein the DNA polymerase lacks 3'-exonuclease activity, and a minority component comprised of at least one thermostable DNA polymerase exhibiting 3'-exonuclease activity, and an improved method for amplifying nucleic acid sequences by polymerase chain reaction wherein the above formulation is mixed and used to catalyze primer extension, are also provided.
Patent NZ-296672-A (NZ)
Title: Touch sensor, electrode pad surrounded by second electrode, electrodes connected by active component mounted on dielectric substrate
Inventor: CALDWELL DAVID W
IPC: H03K17/96
Filed: 1995-10-25
Abstract: A low impedance touch sensor detects manual contact of a dielectric substrate 10 by a human user.  The sensor includes a conductive electrode pad 16, surrounded by an electrode 18, spaced apart by channel 20.  The two electrodes are placed on the undersurface of the dielectric substrate, with the user's touch contact being applied to the opposite surface.  An active electrical component, such as a transistor 26 is located on the substrate and connecting the two electrodes.  A resistor 28 may also connect the electrodes.  The electrode 18 is connected to a strobe line 22, while one terminal of the transistor is connected to sense line 24.
Patent NZ-299611-A (NZ)
Title: Motor vehicle information system querying government vehicle registation database
Inventor: COSTIGAN PATRICK RYAN
IPC: G06F17/30
Filed: 1998-03-18
Abstract: central computer forming a system server is remotely accessible by remote system users and stores vehicle records each having information relating to a respective vehicle.  The remote users may interrogate the central server using vehicle identification data, and in response to such enquiries the server will provide the information relating to the vehicle to which the identification data relates.  The vehicle records in the central server are compiled and updated on receipt of a user enquiry or otherwise, by obtaining vehicle information form at least one remote stored government database of vehicle data for a multiple number of vehicles and by also obtaining information from one or more other remote stored data sources.
Patent NZ-307517-A (NZ)
Title: process for preparing a rigid polyurethane foam using a polyisocyanate in the presence of a blowing promotor
Inventor: DE VOS RIK
IPC: C08G18/30
Filed: 1996-04-16
Abstract: This process is for the preparation of open-celled rigid polyurethane foams and comprises reacting an organic polyisocyanate with an isocyanate-reactive material in the presence of a blowing promotor which is: an isocyanate-reactive cyclic carbonate or cyclic urea, an insoluble organic liquid, a metal salt catalyst ,and a primary diol.
Patent NZ-314238-A (NZ)
Title: Neurokinin derived pseudopeptides; pharmaceutical compositions
Inventor: FAUCHERE JEAN-LUC
IPC: A61P11/00
Filed: 1997-02-14
Abstract: Pseudopeptide neurokinin derivatives of formula (I), their enantiomers, diastereomers, epimers and acid or base addition salts are new. R1 = indolyl, naphthyl, tetrahydronaphthyl, thienyl, Ph (optionally substituted by one or more halo, 1-6C alkyl, 1-6C alkoxy, OH or trihalomethyl) or 3-7C cycloalkyl; n = 1-8; m = 1-4; and R2 = benzyl or Ph (both optionally substituted by one or more halo, 1-6C alkyl, 1-6C alkoxy, OH or trihalomethyl) or 1-6C alkyl.
Patent NZ-320087-A (NZ)
Title: Device for releasably securing an additional wheel to a vehicle wheel
Inventor: SCHAAD FRITZ JOHANN
IPC: B60B11/02
Filed: 1996-10-31
Abstract: PCT No. PCT/CH96/00384 Sec. 371 Date Apr. 27, 1998 Sec. 102(e) Date Apr. 27, 1998 PCT Filed Oct. 31, 1996 PCT Pub. No. WO97/17215 PCT Pub. Date May 15, 1997In a device for detachable fastening of an auxiliary wheel (2) to a wheel (1) of a vehicle, at least one tensioning device (3) is provided with which the auxiliary wheel can be tensioned against the wheel (1) via a distance sleeve (10). The tensioning device (3) has an anchor part (13) which is connected by a wheel bowl of the rim (4) of the wheel (1), and which is provided with an aperture (18) which has a passage (20) with a narrowing (19). A head (21) of a connecting rod (14) can be inserted into the aperture (18) of the anchor part (13), which head is held in the anchor part (13). Disposed on the connecting rod end (14) opposite the head (21) is a tensioning element (15) which can be hung up and tensioned in a part of the rim (8) of the auxiliary wheel (2). With this device the auxiliary wheel (2) can be easily tensioned on the wheel (1), the tensile forces which arise being optimally transmitted.
Patent NZ-334000-A (NZ)
Title: Puncture, pierce, and cut resistant fabric, interlinked platelets held together by rivets
Inventor: KIM YOUNG HWA
IPC: A41D31/00
Filed: 1997-01-22
Abstract: A puncture and cut resistant fabric is formed from identical platelets 12.  The platelets include tabs 25 with hooked ends 20 which allow them to interlink with adjacent platelets.  The platelets are arranged so that alternate platelets are inverted with respect to adjacent platelets.  The platelets have concave cutouts that form apertures 41 when the platelets are linked together.  The apertures are filled by rivets which hold the platelets together.  The hooked tabs allow relative movement of the platelets, allowing the fabric to stretch.  The size of the rivet heads is such that even with the fabric in a stretched state, there are no apertures in the fabric large enough to allow the passage of an object that the fabric is intended to protect against.  The fabric is suitable for surgical or butcher's gloves, or for making bullet-proof garments.
Patent NZ-500599-A (NZ)
Title: Modular interdental brush
Inventor: ZAKSENBERG ISSAC
IPC: A46B7/04
Filed: 1998-04-14
Abstract: The interdental brush has a quadrangular shaped handle portion with an angled brush head portion with a brush head cartridge attached at one end and a removable brush head holder at the other end. The brush head can fit in a contra-angle arrangement or co-directional arrangement to the angle of the handle and the brush head support. In addition, there is a positive grip handle with a projecting thumb finger grip. The removable brush head holder into which the brush head can fit provides a smaller interdental brush and one that can be used away from home.
Patent NZ-501711-A (NZ)
Title: Terminally modified, amino, polyether siloxanes or amino siloxane alkoxylates
Inventor: POLICELLO GEORGE A
IPC: C07F7/08
Filed: 1999-12-10
Abstract: A composition comprising a siloxane of the following formula: ZME2SiO[(Me)2SiO]xSiMe2Q Wherein: X=0 to 2 Q=CaH2aO(C2H4O)b(C3H6O)cR, where: a=2 to 4, b=1 to 12, c=0 to 5; providing that when c is >0, (b+c)=2 to 12, and R is hydrogen, acetyl or a hydrocarbon radical having from one to four carbon atoms, Z is BN[DO(CdH2dO)eR]2-zVz, where d is 2 to 4, e is 0 to 15, z is 0 to 2, V is independently a univalent group, D is independently an alkylene divalent bridging group on which there may be hydroxyl substituents, B is a divalent bridging group, and R is hydrogen, acetyl or a hydrocarbon radical having from one to four carbon atoms. Also disclosed is a method for treating plants by applying the above composition.
Patent NZ-502249-A (NZ)
Title: Naphthyridone antibiotic alatrofloxacin mesylate parenteral compositions
Inventor: GUINN ROBERT MARK
IPC: C07D519/00
Filed: 1998-07-23
Abstract: A process of purifying a compound of formula I is described.  This process comprises treating an impure reaction product which contains an amount of the compound of formula I and less polar impurities with a hydrophobic resin. Also described is a compound of formula I which is substantially free of less polar impurities, the impurities comprising less than 60ppm, relative to the total weight of the compound. Also described are compounds of formulae II and III. Parenteral compositions that comprise an antibacterially effective amount of the compound of formula I or a salt thereof, where the compound of formula I comprises less than 60ppm of less polar impurities relative to the total weight of the compound are also described. Pharmaceutical compositions that comprise an antibacterially effective amount of the compound of formula II or III, or salts thereof are also described.
Patent NZ-503039-A (NZ)
Title: Recombinant porcine adenovirus vector
Inventor: JOHNSON MICHAEL ANTHONY
IPC: C12N15/09
Filed: 1998-08-14
Abstract: A recombinant vector including a recombinant porcine adenovirus, stably incorporating and capable of expression of at least one heterologous nucleotide sequence. The nucleotide sequence is preferably one which encodes an antigenic determinant of Hog Cholera Virus or Pseudorabies virus. Also described is are a method of production of recombinant vectors, methods of preparation of vaccines based on the vectors, administration strategies and methods of protecting pigs from disease.
Patent NZ-503368-A (NZ)
Title: Toothbrush with a valve in the head controlling the dispensing of paste from a reservoir
Inventor: TAGHAVI-KHANGHAH SAID
IPC: A46B11/00
Filed: 1998-08-03
Abstract: The brush comprises a head (36) including a plurality of bristles (40), an outlet (42) in the head (36) feeding to the bristles (40), a container (12) of paste connected to the head (36), actuating means (20) for feeding paste from the container (12) to the head (36), and a control valve (30) of a flexible plastics material including a diaphragm portion (32) and a nose portion (34).  The control valve (30) is positioned within the head (36) with the central axis substantially perpendicular to the direction of flow of paste to the head (36).  The valve (30) has a normal rest position in which the nose portion (34) engages within the outlet (42), as depicted in figure 3a.  The side of the diaphragm portion (32) is remote from the nose portion (34) and is open to the atmosphere.  By depressing the button (26), the bellows (20) is compressed and feeds paste under pressure from the container (12) to the head (36) to distort the diaphragm portion (32).  The nose portion (34) is displaced from the outlet (42) as depicted in figure 3b, and paste is dispensed.   On subsequent release of the bellows (20) the control valve (30) returns to its rest position.  Once the outlet (42) is sealed, no further paste can be extruded and the ingress of water and dirt through the outlet is prevented.
Patent NZ-505103-A (NZ)
Title: Phenylaminoalkylcarboxylic acid derivatives useful as beta 3 adrenoceptor stimulants
Inventor: MUKAIYAMA HARUNOBU
IPC: A61K31/215
Filed: 1998-12-11
Abstract: A phenylaminoalkylcarboxylic acid or a pharmaceutically salt thereof has the formula (I) wherein: R1  is hydroxy, alkoxy, aralkoxy, amino, alicyclic amino  or mono  or  di alkyl amino which may be substituted by hydroxy or alkoxy; R2 is H or alkyl; R3 is H or halogen; R4 and R5 are independently H, halogen or alkyl; A is alkylene; the  carbon labeled  with (R) represents a carbon in the (R) configuration and the carbon labeled with (S)  represents  a carbon in the (S) configuration. The compounds are useful in treating obesity, hyperglycemia, depression, or urinary incontinence.
Patent NZ-505329-A (NZ)
Title: Two heteroaryl or aryl containing compounds covalently attached via a linker useful as muscarinic receptor antagonists
Inventor: MAMMEN MATHAI
IPC: A61K38/16
Filed: 1999-06-07
Abstract: A multibinding compound of formula L-X-L (I) wherein: each L is independently a compound of formula (a), (b), (c), (d), (e), (f), (g) or (h) and X is Xa-Z-(Ya-Z)m-Yb-Z-Xa; m is 0 to 20; each Xa is independently -O-, -S-, -NR-, -C(O)-, -C(O)O-, -C(O)NR-, -C(S)-, -C(S)O-, -C(S)NR- or a covalent bond; each Z is independently optionally substituted alkylene, cycloalkylene, alkenylene, alkynylene, cycloalkenylene or arylene, heteroarylene, heterocyclene, or a covalent bond; Ya and Yb are independently -O-, -C(O)-, -OC(O)-, -C(O)O-, -NR-, -S(O)n-, -C(O)NR'-, -NR'C(O)-, -NR'C(O)NR'-, -NR'C(S)NR'-, -C(=NR')-NR'-, -NR'-C(=NR')-, -OC(O)-NR'-, -NR'-C(O)-O-, -N=C(Xa)-NR'-, -NR'-C(Xa)=N-, -P(O)(OR')-O-, -O-P(O)(OR')-, S(O)nCR'R"-, -S(O)n-NR'-, -NR'-S(O)n-, -S-S- or a covalent bond; A is an aryl or a heteroaryl ring; B is a heterocycloamino group, which optionally attaches X to L; C is an aryl or heteroaryl ring, which optionally attaches the ligand to a linker; GÆ is pyrrolidine, piperidine or a group of formula (2) which optionally attaches L to X; G is aryl, heteroaryl heterocyclic or cycloalkyl, which optionally attaches L to X P is aryl or heteroaryl ring which optionally attaches L to X; S is heterocycloamino which optionally attaches L to X; R20 and R21 are independently hydrogen, alkyl or a covalent bond attaching L to X or together with the nitrogen atom to which they are attached form a heterocycloamino ring, which optionally attaches L to X; R25 and R26 are independently hydrogen, alkyl, aralkyl, or a covalent bond attaching L to X or together with the nitrogen atom to which they are attached form a heterocycloamino group, which optionally attaches L to X; D" is alkylene; D is NR31R32, -N+(R33R34R35) or -OR32; F is -NR40-, -O-, -S- or ûCHR41-; F" is a covalent bond, -OR43, -NR42R43 or -N+R43R44R45 and the rest of the variables are as defined in the specification. The compounds are useful for treating a disease mediated by muscarinic receptor such as chronic obstructive pulmonary disease, chronic bronchitis, irritable bowel syndrome or urinary incontinence.
Patent NZ-506162-A (NZ)
Title: Use of 7-(2-oxa-5,8-diazabicyclo[4.3.0]non-8-yl)-quinolonecarboxylic acid and -naphthyridonecarboxylic acid derivatives for the therapy of helicobacter pylori infections and the gastroduodenal disorders associated therewith
Inventor: MATZKE MICHAEL
IPC: A61K31/47
Filed: 2000-08-04
Abstract: Use of compounds of formula (I) in the manufacture of a medicament for treating Helicobacter pylori infections and gastroduodenal disorders associated therewith, wherein: R1 is selected from alkyl optionally substituted by one or more halogen atoms and phenyl or cyclopropyl, which may optionally be substituted by one or two fluorine atoms; R2 is hydrogen, alkyl optionally substituted by hydroxyl, methoxy, amino, methylamino or dimethylamino or (5-methyl-2-oxo-1,3-dioxol-4-yl)-methyl; A is N or C-R3; R3 is hydrogen, halogen, methyl, methoxy, difluoromethoxy or cyano, or together with R1 can for a bridge of the structure -*O-CH2-CH-CH3 or -*CH2-N-CH3, where the atom marked with * is connected to the carbon atom of A; R4 is hydrogen, benzyl, alkyl, (5-methyl-2-oxo-1,3-dioxol-4-yl)-methyl, -CH=CH-COOR5, -CH2CH2COOR5, -CH2CH2CN, -CH2CH2COCH3 or -CH2COCH3; R5 is methyl or ethyl; R6 is hydrogen, amino, hydroxyl, methyl or halogen.
Patent NZ-507355-A (NZ)
Title: Membrane-bound receptors and their function; cognitive disfunction; treatments therefor; and compositions for use in such treatments
Inventor: XIA ZONGQIN
IPC: A61K36/18
Filed: 1999-03-26
Abstract: Use, in the preparation of a composition for enhancing cognitive function in a human or non-human animal, of one or more of smilagenin, sarsasapogenin, prazerigenin, anzurogenin-D, an astragalosdie, ruscogenin and a steroidal saponin other than a saponin having potent inotropic actions on the myocardium. Also disclosed is the use of said compounds in the preparation of a composition for treating Alzheimers disease, SDAT, Parkinson's disease, postural hypertension, autism, chronic fatigue syndrome, Myasthenia Gravis, Lamber Eaton desease and Gulf War Syndrome.
Patent NZ-510907-A (NZ)
Title: Sugar-free, low-calorie base with polydextrose and mannitol for hard-boiled confections
Inventor: REGAN MICHAEL JOHN
IPC: A23L27/30
Filed: 2000-04-21
Abstract: A base for sugar-free hard-boiled confection includes 85wt% to 97wt% of polydextrose, and from 3wt% to 15wt% sugar alcohol which is predominantly mannitol.  The polydextrose is free of mono- and disaccharides and the base, which is essentially sugar-free, has a caloric content of less than 1.2 kcal/g.  The wt% is based on the combination of the polydextrose and sugar alcohol content.  Of course hard-boiled confections are disclosed which have adequate stability.
Patent NZ-512072-A (NZ)
Title: Compositions and methods for stimulating gastrointestinal motility
Inventor: HAKKINEN JOHN
IPC: A61K31/437
Filed: 2001-05-30
Abstract: Use of a growth hormone secretagogue for the preparation of a medicament for stimulating gastrointestinal transit in a patient.
Patent NZ-512208-A (NZ)
Title: Fruit flavour related genes that control ester formation
Inventor: AHARONI ASAPH
IPC: C07K16/40
Filed: 1999-12-02
Abstract: DNA sequences encoding enzymes involved in the biosynthetic pathway for aliphatic and/or aromatic ester production in fruit are disclosed. The enzymes have alcohol acyl transferase, alcohol dehydrogenase, pyruvate decarboxylase, thiolase, aminotransferase and esterase activities, respectively. The polypeptides having said activities are disclosed. Expression vectors comprising the DNA sequences may be used for regulating ester formation in fruit. Genetically modified plants and microorganisms may be used for producing esters.
Patent NZ-522322-A (NZ)
Title: Polymeric films having anti-static properties
Inventor: PORTER JAMES R
IPC: C08J7/044
Filed: 2001-04-03
Abstract: A process for preparing an anti-static film comprising incorporating a conductivity inducing material into a polymeric film, optionally, during processing of the polymer used to make the polymeric film, during film formation or by a post-treatment process. Anti-static films and films and gloves prepared from such a process are also disclosed.
Patent NZ-524790-A (NZ)
Title: Inhibition of emetic effect of metformin with 5-HT3 receptor antagonists
Inventor: COWLES VERNE E
IPC: A61K31/4178
Filed: 2001-10-16
Abstract: Disclosed herein is a pharmaceutical composition comprising: (i) a pharmaceutically effective amount of metformin; (ii) a 5-hydroxytryptamine-3 receptor antagonist in an amount effective in suppressing emesis that is otherwise caused by said metformin; and (iii) a pharmaceutically acceptable carrier. Metformin is formulated as a pharmaceutical composition that includes a 5-hydroxytryptamine-3 receptor antagonist (such as ondansetron, dolasetron, granisetron, or tropisetron) to suppress the gastrointestinal side effects that are associated with metformin administration in many patients.
Patent NZ-528162-A (NZ)
Title: Method of processing a broadband elastic scattering spectrum obtained from tissue
Inventor: PICKARD DAVID
IPC: G01N21/35
Filed: 2002-02-06
Abstract: A method of processing a broadband optical elastic scattering spectrum obtained from tissue comprises the steps of: obtaining, in a plurality of fitting ranges of wavelength, fitting parameters giving a best fit to the spectrum in the respective fitting ranges; and recording the fitting parameters as a parameter set representing the spectrum; wherein in at least one fitting range the fit is to the absorption of at least one predetermined component, for example, haemoglobin, and in the reminder of the fitting ranges the fit is to a smooth function. The fitting parameters may be used for classifying the tissue, preferably using hierarchical cluster analysis. An apparatus for obtaining elastic scattering spectra from tissue and adapted to process the spectra using the above method is also claimed.
Patent NZ-528218-A (NZ)
Title: Composite bone marrow graft material comprising a porous biocompatible implantable matrix and clot material
Inventor: MUSCHLER GEORGE F
IPC: A61B10/00
Filed: 2002-02-26
Abstract: A composite bone marrow graft material comprising a porous biocompatible implantable matrix and clot material. The composite bone marrow graft material has an enriched population of progenitor cells obtained by flowing a volume of bone marrow aspirate through a comparatively smaller volume of the implantable matrix so that the progenitor cells from the bone marrow aspirate are selectively adhered to the surface of the matrix. The clot material comprises a blood clot, a bone marrow clot, platelet gel, platelet concentrate, fibrin clot material and fibrin glue. Also disclosed are a method and a kit of preparing the composite bone marrow graft material.