baber/WOPTO huggingface dataset:
Patent RU-2742033-C2 (RU)
Title: Combination of fgfr4 inhibitors and bile acid sequestrants
Inventor: FAIRHURST ROBIN ALEC
IPC: A61K31/4545
Filed: 2017-11-01
Granted: 2021-02-01
Abstract: FIELD: medicine; pharmaceuticals. 
     SUBSTANCE: group of inventions relates to the use of a bile acid sequestrant to reduce or prevent the side effects associated with the treatment of liver cancer, including inhibition of FGFR4 by administering N-(5-cyano-4-((2-methoxyethyl)amino)pyridin-2-yl)-7-formyl-6-((4-methyl-2-oxopiperazin-1-yl)methyl)-3,4-dihydro-1,8-naphthyridin-1(2H)-carboxamide (compound A) or a salt thereof, wherein side effects include increasing the level of hepatic enzymes in serum, plasma or blood, or increasing the level of microRNA122; to a pharmaceutical combination for treating liver cancer, containing compound A or its salt and bile acid sequestrant; to use of bile acid sequestrant to reduce or prevent side effects, associated with treating liver cancer with compound A in form of a citric acid salt, wherein the side effect does not include diarrhea; to said use, where the side effects include increasing the level of hepatic enzymes in serum, plasma or blood; and a method of treating liver cancer involving simultaneous or sequential administration of cholestyramine and compound A in the form of a citric acid salt. 
     EFFECT: group of inventions provides reducing or preventing side effects in treating liver cancer with an FGFR4 inhibitor. 
     17 cl, 2 dwg, 1 tbl, 2 ex
Patent RU-2761648-C2 (RU)
Title: Module for growing microgreens from plant seeds and method for growing microgreens from plant seeds
Inventor: Sinitsyn Aleksei Nikolaevich
IPC: A01C1/04
Filed: 2020-01-23
Granted: 2021-12-13
Abstract: FIELD: agricultural technology.SUBSTANCE: invention relates to the field of agricultural technology, to methods for growing microgreens from plant seeds. A module for growing microgreens from plant seeds contains a lower hydrophilic layer of mineral basalt wool and an upper covering layer of breathable paper with one-sided hydrophobic polyethylene coating on the side of the lower layer, attached to the lower hydrophilic layer to form closed pockets for plant seeds. The invention also concerns a method for growing microgreens from plant seeds using the specified module.EFFECT: simplification of the cultivation of microgreens from plant seeds in standard living conditions using water only at the initial stage of moistening substrate with plant seeds located on it.12 cl, 1 tbl, 15 dwg
Patent UA-47726-C2 (UA)
Title: Method for creating an indicator for package opening
Inventor: NEZHURBIDA IHOR ANDRIIOVYCH
IPC: B65D49/12
Filed: 2001-08-16
Abstract: A method for creating an indicator for package opening is in filling the pack with the product, closing it with a cap and fixing a protective element on the surface of it. Protective element is a thread or a band that connects the cap and the pack, at that on the cap or on the pack the thread or the band is fixed by means of a seal made of curing material with provision of the seal or the thread, or the band breaking on the pack opening. On the surface of the seal a pattern is formed. Surface of the cap or the pack that is intended for fixing the seal of curing material is made as being with relief, or rough.
Patent UA-58361-C2 (UA)
Title: Appliance for heating
Inventor: KARBIVNYK LIUBOMYR VOLODYMYROV
IPC: F16L53/00
Filed: 2002-12-03
Abstract: An appliance for heating has placed inside a heat-insulated pipeline electric heating elements. The pipeline with the end flanges is coaxially hermetically connected to the cylindrical housing. The electric heating elements are arranged as installed in the housing in concentric positions inductive electric machine with turbine on the shaft of the rotor. The closed windings of the fixed coil of the machine surrounding the poles of the magnetic-conductive cores are placed with formation of the gaps between neighboring in circle closed windings. The total area of the cross-section of those gaps is not less than the cross-section of the pipeline. Between the ends of the pipeline and the housing there are installed bells made of concentric outer and inner cones.
Patent UA-75363-C2 (UA)
Title: Space solar concentrator
IPC: F24S23/77
Filed: 2001-07-06
Abstract: A space solar concentrator based on light-weight reflectors (3) attached to a honeycomb panel (1) is described. The integration of the reflectors (3) allows for a high modularity. Solar panel deployment is not perturbed by the reflectors (3) even with two-dimensional deployment concept. Each reflector (3) consists in small saw tooth aligned as rows (2) with solar cell rows in between. Low concentration is achieved with a high level of thermal control and a high optical efficiency. When small off-pointing occurs, the solar flux distribution is still the same on each cell. It guarantees a good electrical control and management on the whole panel. The reflectors (3) are preferably made of a thin film tight on a light-weight rigid frame deployed after launch. In another embodiment, the reflector is not deployable and is part of the panel substrate. A stowed configuration allows for superimposition of the solar panel. High reflectivity of the reflectors results from the use of vacuum deposited aluminum of preferentially over-protected silver.
Patent UA-66670-C2 (UA)
Title: A mechanism for cleaning coke ovens doors
Inventor: KALIBERDA MYKOLA STEFANOVYCH
IPC: C10B43/00
Filed: 2003-09-09
Abstract: A mechanism for cleaning coke ovens doors involves framework with vertical guides, at least two carriages, holders, two actuators for cleaning door lining lateral surfaces and drive for reciprocal movement of carriages containing hauling chain disposed on lower sprocket wheels. Each carriage is additionally equipped with at least two actuators for cleaning gas-escape channels of the door, holders of actuators for cleaning sealing frame of actuators have guiding elements; in the lower part of framework between vertical guides a horizontal guide is disposed with carriage placed movably therein, and said carriage carries actuators for cleaning lower brick-holder of the door.
Patent UA-74656-C2 (UA)
Title: Piston
Inventor: YURCHENKO LEONID YAKYMOVYCH
IPC: F16J15/32
Filed: 2004-01-08
Abstract: A piston has a core with support rib and elastic gasket fixed on it. The gasket is arranged with overlap with the support rim of the core, at that the thickness of the gasket over the support rim is not larger than 0.1 of the dimension of the fit diameter of the piston. The support rim has placed in concentric positions with respect to the fit diameter of the piston openings with reboring at the side of low pressure; at that the sum of the areas of cross-sections of the openings is equal to the area of cross-section of the gasket over the support rib.
Patent UA-78828-C2 (UA)
Title: Split sleeve for repair of underwater pipelines
Inventor: LAUS ANATOLII IVANOVYCH
IPC: F16L55/18
Filed: 2005-02-17
Abstract: A split sleeve for repair of underwater pipelines consists of hinged to each other by means of beam two half couplings, the upper and the lower ones, with side semi-circular walls, long flanges with bolt joints, gaskets. The beam is equipped at the ends with two rings arranged with possibility for guide cables to go through those, two supports arranged with possibility of contact with pipeline, and holders arranged with possibility of interaction with cables placed to time of sleeve placement under water on floating mean, for instance pontoon. Technical result is in simplification of structure of sleeve, this promotes decrease of time of implementation of repair works under water.
Patent UA-75010-C2 (UA)
Title: Shaping cutter for restoring the profile of the wheel rim of railroad rolling stock
Inventor: KOLOT VOLODYMYR OLEKSANDROVYCH
IPC: B23C5/14
Filed: 2005-04-18
Abstract: Shaping cutter for restoring the profile of the wheel rim of railroad rolling stock contains a housing with knives. In the knives, in rows in accordance with the profile line adequate to the profile of wheel rim, the cylindrical cutting plates are mounted. These plates are separated between them by partitions. The thickness of partitions along the profile line of base knife is variable and is determined on the basis of the inequality. In this case, the next knives have the arrangement of the first cylindrical cutting plates with a shift along the profile line for an angular value (i. The first plate of base knife is located in the junction of the profile line of ridge part with the profile line of the internal face of bandage.
Patent UA-77872-C2 (UA)
Title: Method for treating esophageal cancer
Inventor: KIRKILEVSKYI STANISLAV IHOREVY
IPC: A61N5/10
Filed: 2005-05-30
Abstract: The objective of the invention consists in the development of the method for treating esophageal cancer using chemo- and radiotherapy with intra-arterial administration of cytostatics allowing for the maximal regression and devitalization of tumor with lower doses of the drugs. The method consists in catheterizing the thyrocervical trunks when the upper esophageal divisions are affected and catheterizing the inferior left diaphragmatic artery and the left gastric artery when the lower esophagealdivisions are affected. The cytostatic drugs are then administered intra-arterially with the concurrent radiotherapy. Two courses of chemo- and radiotherapy are performed.
Patent UA-82679-C2 (UA)
Title: Method and device for determination of weight of load
Inventor: BENDARYK OLEH BORYSOVYCH
IPC: B66C13/00
Filed: 2005-06-03
Abstract: Method for determination of weight of freight prescribes processing of signals for measurement of parameters of load-displacement device by means of trained artificial neutron network. To the inputs of the trained artificial neutron network one feeds signals corresponding to consumed current and voltage of electric motor of load-displacement devices, those are determined at accelerated motion of load displacement. The device for determination of load weight has means for determination of consumed current and voltage of electric motor of load-displacement devices. Electric motor of load-displacement device is three-phase alternating current electric motor each phase of which is equipped with means for determination of consumed current and voltage connected to artificial neutron network.
Patent UA-78652-C2 (UA)
Title: Method of application of coating
Inventor: ZOLOTKO ANDRII NYKONOVYCH
IPC: B05B17/04
Filed: 2005-12-19
Abstract: In accordance with the method of application of coating, on workable surface is coated with material in the form of particles, which is effected by the pressure in such a way that the particles deform the surface and stick to it. Action of pressure on the workable surface is carried out in the liquid medium, for example, in water, which contains the particles of coating material of nanosize, in this case in the liquid ultrasonic fluctuations are generated and highly developed cavitation is created, and the application of coating is carried out by pressure of collapse of cavitation bubbles.
Patent UA-80771-C2 (UA)
Title: Linear induction apparatus
Inventor: ORLOV IHOR IVANOVYCH
IPC: H02K44/00
Filed: 2006-01-16
Abstract: A linear induction apparatus consists of inductors having windings between which a working chamber having rounded sidewalls is installed wherein ferromagnetic working parts are located. According to the invention the working chamber contains a removable end cover being the cover of a loading gate, made doubled; an outside wall has a form and a size of the chamber end and fastens to it by means of sealing elements using warp shackles. The inside wall to which the sealing element is fastened has a form and a size of a chamber cut and made movable along the longitudinal chamber axis relatively to the outside wall.
Patent UA-80213-C2 (UA)
Title: 6,9-diamino-2-ethoxyacridinium 3,5-dinitro-n-(4'-chlorophenyl)-anthranilate having high antimicrobial, antifungal, antiinflammatory, analgesic, diuretic activity and potentiating action toward sodium salt benzylpenicillin
Inventor: ISAIEV SERGII HRYHOROVYCH
IPC: A61K31/435
Filed: 2006-02-27
Abstract: The invention relates to chemicopharmaceutical industry, in particular to the synthesis of novel chemical compounds. A synthesized 6,9-diamino-2-ethoxyacridinium 3,5-dinitro-N-(4'-chlorophenyl)-anthranilate of general formula has high antimicrobial, antifungal, anti-inflammatory, analgesic, diureticactivity and potentiates action of sodium salt benzyl penicillin.
Patent UA-92326-C2 (UA)
Title: Combined chromotherapeutical and shower unit
Inventor: CARRARA ADRIANO
IPC: A47K3/00
Filed: 2007-03-01
Abstract: A combined unit comprising in a single enclosure a chromotherapy device having a plurality of LEDs (102) and a shower water diffuser (121) arranged below. A watertight partitioning wall (111) fabricated from a transparent or translucent material separates the chromotherapy device from a chamber (135) in the same diffuser where the water inlet means (112) end with radial deflectors (117). The chromotherapy light (102) colours the water filling said chamber (135) and the water falling onto the user's body from said diffuser (121) along the LEDs' direction of emission when they are energized.
Patent UA-84378-C2 (UA)
Title: Process for preparation of motor fuels
Inventor: DANYLOV YURII BORYSOVYCH
IPC: C10L1/00
Filed: 2007-08-22
Abstract: The process for preparation of high-octane gasoline and diesel fuel with the low chilling point from the customary hydrocarbon raw material and from the products of alcohol production. The initial hydrocarbon raw material - light fraction of oil or the gas condensate, preliminary is mixed together with several additives, containing alkanols, for example, with the commercial ethyl alcohol or fusel oils, in the amount of 10-25 mass percents and with the sorbent of organic or non-organic origin in the amount of 10-30 mass percents. At that the hydrocarbon raw material is mixed with required amount of additive and with sorbent consequently and portionally with exposition below 20 minutes. The high-octane gasoline and diesel fuel of multigrade application are prepared by direct rectification of the mixture.
Patent UA-89529-C2 (UA)
Title: Coin as carrier of useful substance
Inventor: HUZEIEV OLEH OLEKSANDROVYCH
IPC: A44C21/00
Filed: 2007-10-30
Abstract: The invention relates to coins and can be used in cash money turnover of a state and while producing the coins, substitutes of monetary symbols, medals, tokens and jewelry products. A coin consists of a body and an insert arranged and fixed therein. The insert of the coin is made of porous material and saturated with a useful substance. Plant essential oil or a micronutrient necessary for human organism can be used as a useful substance. The invention allows increasing the emission profit by means of giving new consumer’s properties to the coin, lowering production costs of making thereof and providing the high level of protecting thereof from counterfeiting.
Patent UA-83783-C2 (UA)
Title: Method for evaluation of quality of tests of fire resistance of building constructions
Inventor: KHARCHENKKO IHOR OLEKSANDROVYCH
IPC: A62C99/00
Filed: 2007-11-01
Abstract: The invention relates to tests of building constructions on fire resistance and can be used for determination of limit of fire resistance of any building constructions and building articles (partitions, floors, covers, columns, beams, air ducts, cable passages, etc.). The method includes control of quality of values of average temperatures of each test with measurement with thermo-couples installed in fire furnace. Use of the method proposed makes it possible to compare through keeping at one level quality of heat effect on sample, in particular through keeping at needed level homogeneity of temperature field in fire furnace, to compare quality of thermal effect on sample being tested, and, respectively, quality of testing as well.
Patent UA-93509-C2 (UA)
Title: METHOD FOR PREPARING metallic workpieces for cold forming AND APPLICATIONS thereof
Inventor: NITTEL KLAUS-DIETER
IPC: C25D11/00
Filed: 2006-03-05
Abstract: The invention relates to a method for preparing metallic workpieces for cold forming by contacting the metallic surfaces thereof with an aqueous acid phosphating solution so as to embody at least one phosphate coating and then coating the phosphate-coated surfaces with at least one lubricant in order to embody at least one lubricant layer. According to the inventive method, the phosphating solution essentially contains only calcium, magnesium, or/and manganese as cations that are selected among cations of main group 2 and subgroups 1, 2, and 5 to 8 of the periodic table of chemical elements in addition to phosphate. Furthermore, an alkaline earth metal-containing phosphating solution is free from fluoride and complex fluoride while the phosphating process is carried out electrolytically. The invention further relates to a metallic workpiece that is coated accordingly as well as the use of workpieces coated in said manner.
Patent UA-99589-C2 (UA)
Title: Method and apparatus for water treatment
Inventor: VROOM IAN DOUGLAS
IPC: C02F1/78
Filed: 2006-10-27
Abstract: A method and apparatus for treating water such as ballast water in ships in order to eliminate aquatic organisms in the water. The water is led under pressure through a conduit into a chamber of greater cross-section than that of the conduit so that an abrupt reduction in pressure occurs. Cavitation ensues, leading to the release of dissolved gases. Ultrasonic vibration is generated and is applied to the water, exerting a pounding effect that weakens or destroys the organisms present. As cavitation generator the system of successively placed cone chambers is used, at the inlet of which ring disk with a central opening is fixed. The inventions contribute to the complex treating of water and its decontamination from aquatic organisms.
Patent UA-90956-C2 (UA)
Title: Cleaner of tuberous root heads
Inventor: BULHAKOV VOLODYMYR MYKHAILOVYCH
IPC: A01D23/02
Filed: 2008-12-10
Abstract: In a cleaner of tuberous root heads each cleaning blade comprises an axle on which the upper ends of two additional blades forming a V-like profile are mounted. Middle parts of the additional blades are connected between each other by pressure springs, rigidity thereof are lesser than rigidity of the cleaning blades, and working surfaces have profiles of truncated cones. Such construction of the device allows raising the effectiveness of cleaning of beet root heads from residues of tops not yet cut down by 15...20%.
Patent UA-93727-C2 (UA)
Title: “cytron karat”, liquor
Inventor: TRYHUB OLEKSANDR VITALIIOVYCH
IPC: C12G3/06
Filed: 2009-03-03
Abstract: The invention relates to liquor production. Liquor contains aromatic alcohol of lemon essential oil, citric acid, tartrazin, sugar syrup (65.8%) and aqueous-alcoholic liquid from “Extra”, rectified ethyl alcohol and prepared potable water – the rest for the strength of blend of 25% vol. Liquor has consistent sweet taste and refreshing aroma of natural lemon, attractive golden yellow color, and healing properties.
Patent UA-90815-C2 (UA)
Title: device for diagnostics of backbone state at bearing disorders
Inventor: FILAK YAROSLAV FELIKSOVYCH
IPC: A61B6/02
Filed: 2009-03-10
Abstract: The invention relates to medicine, namely to devices for backbone diagnostics at bearing disorders, and can be used for determination of a degree of a deviation of a backbone from normal position.A device for diagnostics of backbone state at bearing disorders comprises measurement of levels of accommodation of humeral shoots across by a scale with index in degrees, measurement of backbone curvature in face-to-face and saggital planes by vertically located temple and a ruler, according to the invention.The equality of humeral shoots across are measured additionally by means of two connected flexible tubes of vertically placed vessels filled with liquid with divisions in millimeters. An existing adjustable coat hanger allow to take measurements depending on anthopometrical data and age category of patients.The claimed invention can be used in clinical practice of orthopedists, rehabilitation specialists, pediatrists, as well as in scientific researches on study, treatment and rehabilitation of bearing disorders and scoliosis. dystrophies and optic neuropathies.
Patent UA-89918-C2 (UA)
Title: Process for the preparation of silicon of high purity
Inventor: OHENKO VOLODYMYR MYKHAILOVYCH
IPC: C01B33/00
Filed: 2009-03-11
Abstract: The invention relates to chemical technology, namely to a process for the preparation of silicon of high purity, obtained by the synthesis, treatment and decomposition of silicon-containing compounds, which can be used in semiconductor industry, production of elements of solar energy, raw material for the synthesis of materials for electronic technology, etc. During the process for the preparation of silicon of high purity the interaction of the initial components is carried out by their circulation in closed technology cycle, primary in hydrogen stream, activating components by the action of mechanical inertial forces with the decomposition of solid particles in the result of compression, friction and impaction of them with each other, formation in electric filed of energy-saturated silicon- and hydrogen-containing components with their further interaction with formation of silane, its treatment and decomposition to silicon. The technical result: the developed process for the preparation of silicon of high purity by intensification of interaction processes of initial components and the obtained products in ecologically clean closed technology process, short-cut technology operations, increased degree of treatment of initial components, decreased power consumption and production cost of silicon, expanded raw-material base.
Patent UA-98141-C2 (UA)
Title: Methods of treating with quinaxoline inhibitors of pi3k-alpha
Inventor: LAMB PETER
IPC: A61K31/337
Filed: 2008-04-08
Abstract: The present invention provides methods of treating cancer by administering a compound of Formula Ia, optionally as a pharmaceutically acceptable salt, solvate and/or hydrate thereof, in combination with other cancer treatments.
Patent UA-106347-C2 (UA)
Title: Strike plate for spring-latch locks
Inventor: ALBAN ANTONIO MARIO
IPC: E05C1/00
Filed: 2010-04-28
Abstract: A strike plate (10) for spring-latch locks (11), to be associated with a support (12) constituted by a frame of a door or window or by a leaf and provided with a spring-latch hole (13) in a position that corresponds to the spring latch (14) in order to receive it when the lock (11) closes. The strike plate (10) comprises - a body (15), which forms a receptacle (16) for the spring latch (14), to be positioned at the spring-latch hole (13), - means (17) for fixing the body (15) to the support (12), - at least one faceplate (18) for covering the body (15) and the fixing means (17), and adapted to conceal them when they are installed, - means (19) for associating the faceplate (18) with the body (15). The association means (19) are of the snap-acting type, comprising toothed tabs (22) that protrude from a first component chosen between said at least one faceplate (18) and said body (15), the other one of said components having engagement undercuts (23) for said toothed tabs (22), said toothed tabs (22), engaged with said undercuts (23), jointly connecting said at least one faceplate (18) to said body (15).
Patent UA-95195-C2 (UA)
Title: Agent for removal of neoplasia of the skin tissues
Inventor: SELIKHOV SERHII VOLODYMYROVYCH
IPC: A61K36/66
Filed: 2010-06-17
Abstract: The invention relates to medicine, concerns the removal of neoplasia of the skin tissues, such as corns, warts, papillomas. It contains a mixture of potassium hydroxide and sodium hydroxide at a ratio of 1:6 and extract of celandine herbs.