baber/WOPTO huggingface dataset:
Patent CA-2630270-A1 (CA)
Title: 5-substituted indole-2-carboxamide derivatives
Inventor: RICHTER HANS
IPC: A61K31/404
Filed: 2006-11-20
Abstract: The present invention relates to compounds of formula (I) wherein R1 to R4 and G are as defined in the description and claims and pharmaceutically acceptable salts thereof. The compounds are useful for the treatment and/or prevention of diseases which are associated with the modulation of H3 receptors.
Patent CA-2631209-A1 (CA)
Inventor: KRENER OLIVIER
IPC: G06Q10/00
Filed: 2008-05-14
Abstract: A system is described for determining a relative location of a plurality of items upon a plurality of platforms. The system may include a memory, an interface, and a processor. The memory may store a first item, a second item, a first period of time and a second period of time. The interfa ce may be operative to communicate with a user and an antenna. The antenna may be able to detect an item for a period of time. The processor may be operative to receive from the antenna, via the interface, the first item, the first perio d of time, the second item and the second period of time. The processor may determine whether the periods of time overlap. If the periods of time overlap the processor may communicate to the user that the items are upon the same platform, otherwise that the items are on consecutive platforms.
Patent CA-2631339-A1 (CA)
Inventor: VALENTINI DAVID
IPC: G02B5/00
Filed: 2006-11-27
Abstract: The invention concerns an optical instrument (1) comprising at least one mirror called primary mirror (3), arranged in a cavity (2) and comprising an active surface capable of being subjected to instantaneous variations of the incident radiant flux. The invention is characterized in that the cavity (2) comprises an inner rigid envelope (20) around the mirror made of a material having thermal inertia so as to dampen the instantaneous variations of the incident radiant flux thereby enabling the temperature fluctuations of said cavity to be limited, and hence, the fluctuations of the mirror. The invention is applicable to the field of space technology.
Patent CA-2631835-A1 (CA)
Inventor: HOFFMANN HANS-RAINER
IPC: A61M5/315
Filed: 2007-08-31
Abstract: The application relates to a cylinder/piston unit with a cylinder (10) and with a piston (50) which is guided therein and which is sealed off in a sterile manner by a rubber seal, wherein the cylinder (10) and the piston (50) enclose a chamber (30) that can be filled at least temporarily with active substance, and the cylinder has at least one discharge element (36) at its front end. When the piston (50) is actuated, two individual static sealing elements (65, 85) are transferred from their respective sealing position (67, 87) into a parked position (69, 89) located in the parking area (68, 88), wherein each sealing element (65, 85) in the parked position (69, 89) touches only the cylinder wall (47, 48) or only the piston wall (64, 84).
Patent CA-2633127-A1 (CA)
Title: Method of producing rough strains of mycobacterium bacteria and uses thereof
Inventor: BOTTASSO OSCAR ADELMO
IPC: A61K39/00
Filed: 2006-12-19
Abstract: The present invention relates to a method of producing rough strains of a bacterium, such as Mycobacterium obuense, said method comprising exposing said bacterium to a sulfone and/or sulfonamide (such as 4,4'-Diaminodiphenyl sulfone or an ana-logue thereof). A rough strain of Mycobacterium obuense producible by said method and uses thereof. In particular, uses of a rough strain of Mycobacterium obuense deposited under the Budapest Treaty at the NCTC with the accession number NCTC 13365.
Patent CA-2633468-A1 (CA)
Inventor: TIMMUSK TONIS
IPC: C07K16/22
Filed: 2005-12-14
Abstract: The present invention discloses a novel neurotrophic factor protein, MANF2 and a genetic sequence encoding the same. The molecule will be useful in the development of a range of therapeutics and diagnostics useful in the treatment, prophylaxis and/or diagnosis of MANF2 dependent conditions. The molecule of the present invention is also a useful effector of primary and central neurons, especially dopaminergic neurons at the central nervous system and growth factor genes.
Patent CA-2635119-A1 (CA)
Inventor: SEXTON BONNIE COLLETT
IPC: G06F7/499
Filed: 2007-01-22
Abstract: A pre-saturating multiplier inspects the operands to a multiply operation prior to performing any multiplication. If the operands will cause an overflow requiring saturation, the multiplier outputs the saturated value without multiplying the original operands. In one embodiment, parameters derived from the operands are altered such that when the multiply operation is performed on the altered parameters, the multiplier produces the saturated result. This may comprise altering a Booth recoded bit group to select a negative zero instead of a zero as a partial product, and suppressing the addition of the value one to the partial products (thus effectively subtracting the value one). In another embodiment, when the operands that will cause an overflow are detected, the output of the multiplier is forced to a predetermined saturation value.
Patent CA-2639661-A1 (CA)
Title: Aggregate delivery unit
Inventor: ENGLAND KEVIN W
IPC: E21B43/267
Filed: 2008-09-19
Abstract: A delivery unit for providing aggregate to a worksite, such as a wellsite location. The unit may include a mobile chassis for accommodating a plurality of modular containers which in turn house the aggregate. As such, a weight measurement device may be located between each container and the chassis so as to monitor aggregate levels within each container over time. The units may be particularly well suited for monitoring and controlling aggregate delivery during a fracturing operation at an oilfield.  The modular containers may be of an interchangeable nature. Furthermore, a preferably wireless control device may be provided for monitoring and directing aggregate delivery from a relatively remote location.
Patent CA-2641249-A1 (CA)
Inventor: WOO HENRY
IPC: A61F2/966
Filed: 2007-02-01
Abstract: A method for increasing blood flow through an obstructed blood vessel includes providing an expandable member (100) made of a mesh having a plurality of interstices. The expandable member is substantially closed at the distal end and is inserted into the vessel and positioned within the vessel with the member body located radially adjacent at least a portion of an obstruction.  The expandable member is expanded into contact with the obstruction. An outward radial force is exerted on the obstruction to dislodge a fragment. The fragment is passed through at least one interstice of the member body in the radial direction, the fragment being selectively retained. An apparatus for increasing blood flow through an obstructed blood vessel is also provided.
Patent CA-2644771-A1 (CA)
Inventor: DION JONATHAN
IPC: A61B6/00
Filed: 2007-03-02
Abstract: The present invention relates to the use of polymers as contrast agents for ultrasounds. The idea is to have a molecular imprint in the polymer that is specific for a given molecule or analyte. When that molecule binds to the polymer it induces a conformational change that results in an increase in the ultrasound signal, referred to as a target-bound state. The method can also be used for example for quantitative measurements of analytes.
Patent CA-2645545-A1 (CA)
Inventor: PARSONS KIERAN
IPC: H04B15/00
Filed: 2007-04-10
Abstract: A circuit for communicating information in a wireless network includes a filtering circuit in communication with a zero intermediate frequency (ZIF) transceiver circuit. The filtering circuit includes a first mixer in communication with an output of the ZIF transceiver circuit. The filtering circuit includes a first Surface Acoustic Wave (SAW) filter circuit in communication with an output of the first mixer. The filtering circuit includes a second mixer in communication with an output of the first SAW filter circuit. The filtering circuit includes a third mixer, and a second SAW filter circuit in communication with an output of the third mixer. The filtering circuit includes a fourth mixer in communication with an output of the second SAW filter circuit and an input of the ZIF transceiver circuit. The filtering circuit also includes a local oscillator circuit in communication with the first, second, third and fourth mixers.
Patent CA-2646405-A1 (CA)
Inventor: MOOSAVI VAHID
IPC: G06F3/0482
Filed: 2008-12-12
Abstract: A handheld electronic device includes a display screen located on the device.  The handheld electronic device features a body housing a microprocessor-run software application program that displays a menu including available user actions on a display screen of the handheld electronic device. The microprocessor-run software application displays a plurality of legends at a lateral side of the displayed menu based on receipt of a cursor position data indicating that the cursor on the display screen is in a proximate area of the display screen on which the plurality of legends display.
Patent CA-2646874-A1 (CA)
Title: Processes for preparing (e)-styrylbenzylsulfone compounds and uses thereof for treating proliferative disorders
Inventor: REDDY SIRIGI
IPC: C07C303/30
Filed: 2008-12-17
Abstract: Processes for preparing (E)-2,4,6-(Trimethoxystyryl)-3-0-Phosphate Disodium-4-Methoxybenzyl Sulfones and uses thereof as antiproliferative agents, including, for example, anticancer agents, and as radioprotective and chemoprotective agents.
Patent CA-2647443-A1 (CA)
Inventor: KOLMES NATHANIEL
IPC: D04B1/24
Filed: 2007-05-18
Abstract: A cut, slash and/or abrasion resistant fabric Is provided having both high cut resistance and light fabric weight, preferably a cut resistance of at least 500 (as measured by ASTM-Fl 790-04) and a fabric weight of no more than 27.9 ounces/square yard (OPSY), which can be prepared, if desired, by shaped knitting into a shaped fabric panel, which is used to prepare cut, slash and/or abrasion resistant garments or coverings.
Patent CA-2647685-A1 (CA)
Inventor: LEE GENE W
IPC: C12N15/113
Filed: 2007-04-19
Abstract: The invention provides novel inhibitory polynucleotides directed against IRES sequences. The invention also provides genetically engineered expression vectors, host cells, transgenic animals, and transgenic plants comprising the novel inhibitory polynucleotides of the invention. The invention additionally provides methods of using the inhibitory polynucleotides of the invention.
Patent CA-2649489-A1 (CA)
Inventor: MESTROVIC ERNEST
IPC: A61K31/663
Filed: 2007-03-06
Abstract: The present invention is concerned with new risedronate salts and new polymorphic forms thereof, specifically a pharmaceutically acceptable tetra-(alkali metal) salt of risedronic acid and new polymorphic forms thereof, processes of preparing the same, pharmaceutical compositions containing the same, therapeutic uses thereof and methods of treatment employing the same.
Patent CA-2649789-A1 (CA)
Title: Micro-structured insulating frame for electrolysis cell
Inventor: KIEFER RANDOLF
IPC: C25B9/19
Filed: 2007-04-27
Abstract: The invention relates to an insulating frame (4) of an electrolysis cell having a microstructured internal section (9) allowing the penetration of the electrolyte even if the structured section is partly or completely overlapped by the membrane (1), and to an electrolysis cell equipped with the same.
Patent CA-2656139-A1 (CA)
Title: Systems and methods for cryopreservation of cells
Inventor: WOODS ERIK JOHN
IPC: C12N1/04
Filed: 2007-06-19
Abstract: An auto-nucleating device includes a hollow tube containing a crystalline cholesterol matrix therein. The ends of the tube are closed by a membrane that is impermeable to the cholesterol but permeable to liquids contained in a cryopreservation vessel. The auto- nucleating device is disposed within the vessel and provides a site for ice nucleation during freezing of the liquid within the vessel. One such cryopreservation vessel is a flexible vial having a closed port at one adapted to be pierced by a needle to withdraw the liquid within. The opposite end of the vial is initially open to receive the liquid. The end is then sealed to form a closed system for cryopreservation. Another cryopreservation vessel includes an adaptor mounted to a port of a liquid container. The adaptor includes one tubular branch that is closed by a needle septum while another tubular branch includes a barbed fitting for engaging a flexible tube. The flexible term terminates in a needle septum. The container is initially at below-atmospheric pressure. In use, the liquid sample is injected by needle through the septum in the second branch. Once the container is filled with the sample, the flexible tube is heat sealed and severed just above the barbed fitting. The sealed container may then be subject to a cryopreservation protocol. After thawing, the sample liquid may be withdrawn by a needle puncturing the septum in the first branch.
Patent CA-2663904-A1 (CA)
Title: Method and apparatus for encoding and decoding audio signals
Inventor: KANDHADAI ANANTHAPADMANABHAN A
IPC: G10L19/20
Filed: 2007-10-08
Abstract: Techniques for efficiently encoding an input signal are described. In one design, a generalized encoder encodes the input signal (e.g., an audio sign al) based on at least one detector and multiple encoders. The at least one d etector may include a signal activity detector, a noise-like signal detector , a sparseness detector, some other detector, or a combination thereof. The multiple encoders may include a silence encoder, a noise-like signal encoder , a time-domain encoder, a transform-domain encoder, some other encoder, or a combination thereof. The characteristics of the input signal may be determ ined based on the at least one detector. An encoder may be selected from amo ng the multiple encoders based on the characteristics of the input signal. T he input signal may be encoded based on the selected encoder. The input sign al may include a sequence of frames, and detection and encoding may be perfo rmed for each frame.
Patent CA-2664640-A1 (CA)
Title: Intervertebral prosthesis endplate having double dome and surgical tools for implanting same
Inventor: MAKRIS GEORGE
IPC: A61F2/44
Filed: 2007-09-26
Abstract: An endplate for an intervertebral prosthesis includes : a generally- planar base plate (162 ), a f irst elevated region ( 152 ), or dome, within the base plate periphery, and a second elevated region ( 153 ), or dome, within the boundary (164 ) of the f irst elevated region. The antero-posterior and side-to-side (medial-lateral ) dimensions of the f irst elevated region are made to be unequal in order to provide resistance to torsional stresses, and the laterally opposite sidewalls of the f irst elevated region are def ined by arcs that terminate in sagittal planes of the endplate, and are symmetrical with respect to a coronal plane of the endplate. A bone rasp (201 ) for preparing a surgical site for implantation of the prosthesis has a rasp head (202 ) having a pivot point and rasp teeth (224 ) arranged to produce a recess or seat of predetermined shape. A groove-cutter (300 ) for preparing a medial antero- posterior groove in a vertebral body without damaging the anterior rim of the vertebral body has a guide head that is seated in a prepared recess in the vertebral body and a reciprocable tooth ( 301 ) that can be stowed in a recess while the cutter is initially positioned within the intervertebral space.
Patent CA-2665223-A1 (CA)
Inventor: CRAVATT BENJAMIN F
IPC: A61K31/00
Filed: 2007-10-02
Abstract: A multidimensional profiling strategy that combines activity-based proteomics and metabolomics was used to determine that an active protein, which is a previously uncharacterized enzyme highly elevated in aggressive cancer cells, serves as a central node in an ether lipid signaling network that bridges platelet-activating factor and the lysophospholipids. Biochemical studies confirmed that the active protein regulates this pathway by hydrolyzing the metabolic intermediate 2-acetyl monoalkylglycerol. Inactivation of the active protein disrupted ether lipid metabolism in cancer cells and impaired cell migration and tumor growth in vivo.
Patent CA-2665416-A1 (CA)
Title: Connector balancer
Inventor: MCKAY CHARLES D
IPC: F16B7/18
Filed: 2009-03-17
Abstract: The Connector Balancer is an externally threaded fastening system which is glued in place to connect, align, and balance internally like threaded rod sections without any air pockets thusly creating an ideal balanced joint and finished assembly. The construction materials and dimensions are varied to achieve a precise weight, balance, and structural characteristics.     There are two main components.     For blind joints there is a threaded tube 1 with adhesive vent hole 14 into which two hollow plugs 2 or 3 fit which act as a pump when screwing the joint together removing excess glue and air through the centre hole of the hollow plugs 2 or 3 and out the glue vent hole 14 in the threaded tube 1 and past the mating surfaces of the pieces to be joined until the joint closes completely and the joint is sealed.   For one side open (end) joints an externally threaded hollow tube 4 having an an internal thread and internal lathe centre and plug 5 forces the glue to the next joint or back out a glue vent in the like threaded sections to be joined creating a void free joint. The internal thread facilitates a screw in plug or attachment and the lathe centre allows mounting between centres.
Patent CA-2667335-A1 (CA)
Inventor: FARINA DINO J
IPC: G01M99/00
Filed: 2007-11-09
Abstract: An automated system (100) for testing a spray pump assembly includes a system computer (114), a robotic handler (120), holder tray (210), actuator, and analytical balance (255). The system computer issues commands to the robotic handler to handle and to transport spray pump assemblies, collection vessels, waste collectors, and nozzle tip dabbers. The robotic handler includes an electromechanical gripper capable of handling objects of varying sizes and sensing contact between gripped objects and another object. The robotic handler may also perform shaking functions. The holder tray, actuator, and other system elements may include sensors for detecting the presence of testing objects. The spray pump assembly may include a collet with a tapered and threaded aperture for securing the collet to a spray pump. The system may further include an elevator assembly for positioning and transporting the actuator (while holding a spray pump assembly) between a first testing area and a second testing area.
Patent CA-2668971-A1 (CA)
Title: Multimedia emulation of physical reel hardware in processor-based gaming machines
Inventor: WILLIAMS DAVID C
IPC: G07F17/32
Filed: 2007-11-12
Abstract: Gaming machines, systems and methods for providing more realistic emulations of rotating reels are disclosed. Gaming machines include an exterior housing, master gaming controller, display device, speakers and virtual reels. A reel spin timer can be adapted to vary the spin times of the simulated rotating reels from one game play to another, and a reel sound generator can be adapted to provide reel sounds to one or more speakers with respect to the simulated rotating reels. Provided reel sounds can also vary from one game play to another, and both reel spin times and reel sounds can be selected randomly from stored values or files. Stored values or files can include samplings from actual physical reels. A remote host can provide downloadable reel spin times and reel sounds to gaming machines within an associated gaming system.
Patent CA-2669233-A1 (CA)
Inventor: BOKER FRANCISCO
IPC: A01K13/00
Filed: 2007-11-06
Abstract: The invention concerns an absorbent composition comprising: (a) at least 50 wt.-% of the overall composition have a particle size of less than 150 µm and are comprised of at least one absorbent component; and (b) at least 1.0 wt.-% of the overall composition have a particle size of at least 250 µm and are comprised of at least one particulate component, and its preferred uses.
Patent CA-2674902-A1 (CA)
Title: Improved process for the preparation of oxidized phospholipids
Inventor: KOVALEVSKI-ISHAI ETI
IPC: C07F9/02
Filed: 2008-01-02
Abstract: Novel synthetic routes, which are highly applicable for industrial preparation of therapeutically beneficial oxidized phospholipids are disclosed. Particularly, novel methods for efficiently preparing compounds having a glycerolic backbone and one or more oxidized moieties attached to the glycerolic backbone, which are devoid of column chromatography are disclosed. Further disclosed are novel methods of introducing phosphorous-containing moieties such as phosphate moieties to compounds having glycerolic backbone and intermediates formed thereby.
Patent CA-2676103-A1 (CA)
Title: External bra pads, but internal pads called the bra pets pads
Inventor: MANJAPRA JEANILE
IPC: A63H33/00
Filed: 2009-07-28
Abstract: This invention's main idea is to provide More..... breast and relates first to a satellite dish for its working center. The center causes the bra to stay in place. Next, it relates best to two identical clam shells for their fan - like, spherical - circular shape for all around support. It relates to pillows for its comfort, especially if it made from the bubble wrap material. Two layers of bubble wrap with an extra small insert for center stitching is the key action to shaping the bra pad. Later the inside stuffing is wrapped in a safe fabric for wearing close to the body.  The stuffing is covered by a fine fabric for wearing close to the skin.  Stitching this in a circular way will allow the Bra Pet to form a dish - like appearance. Continued stitching from the center to the outer soft rim allows it to look like a clam shell. These different stages are the key to the Bra Pet invention. See GT 6 - 17 It relates to a saucer's center. The center of the breasts is aligned with the center of the pads in order to perform with the body"s movement. With its firm center and with its parabolic shape, all of these attributes make these external Bra Pets ability to provide More..... breast for the customer.
Patent CA-2676252-A1 (CA)
Inventor: DONDE YARIV
IPC: C07D277/56
Filed: 2008-01-21
Abstract: Disclosed herein is a compound of the formula (I). Therapeutic methods, compositions, and medicaments, related thereto are also disclosed.
Patent CA-2676759-A1 (CA)
Title: Prostaglandin synthesis and intermediates for use therein
Inventor: ALBERICO DINO
IPC: C07D311/94
Filed: 2009-08-26
Abstract: Fused cyclopentane - 4-substituted 3,5-dioxalane lactone compounds useful as an intermediate in the synthesis of prostaglandin analogs are provided. The compounds have the formula A:     (see formula A) wherein R represents an aryl group such as p-methoxyphenyl.   This compound can be reacted with a lower alkyl aluminum compound to open the dioxalane ring and reduce the lactone to lactol, without over-reducing to diol. The resulting compound can be functionalized to insert chemical side groups of target prostaglandins, adding the required a-side chain and then the required .omega.-side chain sequentially and independently of each other. The compounds and process are particularly suitable for preparing lubiprostone.
Patent CA-2677163-A1 (CA)
Inventor: ROSCHKE VIKTOR
IPC: A61P37/00
Filed: 2008-01-29
Abstract: Disclosed are humanized antibodies that bind specifically to the receptor CXCR3. The humanized antibodies may be antagonists and may used to treat or diagnose conditions associated with CXCR3 function.