baber/WOPTO huggingface dataset:
Patent NZ-611583-A (NZ)
Title: Shims for building construction
Inventor: CONNELL ROBERT URQUHART
IPC: E06B1/60
Filed: 2010-03-15
Abstract: A shim (50), moulded from plastic material, for supporting or levelling a concrete slab in building construction is disclosed. Generally frustoconical or cylindrical shaped voids (52) extend from at least one edge of the shim into the interior. The voids are arranged in the shim with their longitudinal axes in parallel relationship. The voids reduce the volume of plastic required in manufacture. The frustoconical or cylindrical shape of the voids facilitates retraction of mould cores after moulding.
Patent NZ-626699-A (NZ)
Title: Dpa-enriched compositions of omega-3 polyunsaturated fatty acids in free acid form
Inventor: MAINES TIMOTHY J
IPC: C07C57/02
Filed: 2013-01-04
Abstract: Disclosed is the use of a pharmaceutical composition comprising: eicosapentaenoic acid (“EPA”), in a weight percent amount of 50% to 60%; docosahexaenoic acid (“DHA”) in a weight percent amount of 17% to 23%; docosapentaenoic acid (n-3) (“DPA”) in a weight percent amount of 1% to 8%; wherein at least 90% by weight of the polyunsaturated acid in the composition is present in the free acid form, in the manufacture of a medicament for the treatment of severe hypertriglyceridemia, wherein the treatment comprises: orally administering the to a patient having pre-treatment serum or plasma triglyceride levels ≥500 mg/dL, in an amount and for a duration effective to reduce serum or plasma triglycerides below pre-treatment levels. Also disclosed is the use of a pharmaceutical composition comprising: EPA, substantially in free acid form, in an amount of 55.1% (m/m) to 58.4% (m/m); DHA, substantially in free acid form, in an amount of 17.7% (m/m) to 22.2% (m/m); and DPA, substantially in free acid form, in an amount of 2.1% (m/m) to 8.5% (m/m); in the manufacture of a medicament for use in the treatment of a patient with elevated pretreatment serum or plasma triglycerides, wherein the treatment comprises: administering the medicament in an amount and for a duration effective to reduce arachidonic acid (AA) concentration in plasma by at least about 5%. Further disclosed is a method of making a pharmaceutical composition of polyunsaturated fatty acids in free acid form, the method comprising: (a) subjecting an intermediate feedstock of transesterified fish oil comprising the ethyl esters of EPA, in an amount of at least about 44% (a/a), DHA, in an amount of at least about 14% (a/a), and DPA, in an amount of at least about 1% (a/a), to a step of urea inclusion complexation; (b) removing the resulting urea complexes; and (c) hydrolyzing the uncomplexed PUFA esters to free fatty acids; wherein the amount of urea used for complexation is calculated according to formula I(a), or according to formula I(b), or according to both formula I(a) and formula I(b) wherein the urea amount is set to a value within the range set by, and inclusive of, the results of formulae I(a) and I(b); and wherein formula (Ia) and formula (Ib) are as defined herein.
Patent NZ-628394-A (NZ)
Title: Treatment method for steroid responsive dermatoses
Inventor: AGARWAL PANKAJ
IPC: A61P17/06
Filed: 2013-04-22
Abstract: Disclosed is a use of a therapeutically effective amount of a compound selected from the group consisting of: N-{ (1S)-2-Amino-1-[(3-fluorophenyl)methyl]ethyl} -5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecarboxamide or a pharmaceutically acceptable salt thereof, and N-{ (1S)-2-amino-1-[(3,4-difluorophenyl)methyl]ethyl} -5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-furancarboxamide or a pharmaceutically acceptable salt thereof in the manufacture of a medicament for use in the treatment of steroid responsive dermatoses in a mammal, wherein the steroid responsive dermatoses is selected from: contact dermatitis, eczema, infantile eczema, atopic dermatitis, ichthyosis, psoriasis, xeroderma, seborrheic dermatitis, nummular dermatitis, dermatitis herpetiformis, neurodermatitis, stasis dermatitis, lichen simplex chronicus, dermatophytids, candidiasis, intertrigo, scabies, pityriasis rosea, lichen planus, pityriasis rubra pilaris, bullous pemphigoid, miliaria, acute and chronic eczema, lupus erythematosis, photoallergic reactions, pruritis, and combinations thereof.
Patent NZ-701129-A (NZ)
Title: Framework serving as structural support and utility space
Inventor: THOMPSON J MARTIN LOVELY
IPC: E04B1/348
Filed: 2013-03-20
Abstract: A framework for a building structure. The framework is constructed of two open-walled structures, an inner core structure and an outer core structure. Each core structure is a six-sided cuboid structure formed by hollow horizontal and vertical conduits. The inner core structure is smaller than the outer core structure and interconnecting hollow conduit webs link the two cores. The inner core may be placed on a different horizontal plane than the outer structure, in which case, the interconnecting webs slope from one core to the other one. The conduits of the cores are dimensioned to house utility systems, such as plumbing, wiring, staircases, etc. Walls, windows, doors may be attached to the core structures, to achieve a residential or commercial space suitable for the intended purpose.
Patent NZ-705526-A (NZ)
Title: Hepatitis b virus core protein and surface antigen protein and vaccine comprising the same
Inventor: WEINER DAVID B
IPC: C12N15/63
Filed: 2013-09-19
Abstract: Provided herein are nucleic acid sequences encoding hepatitis B virus (HBV) core proteins, surface antigen proteins, fragments and combinations thereof as well as genetic constructs/vectors and vaccines that express said protein sequences. These vaccines are able to induce an immune response peripherally and in the liver by recruiting both cellular and humoral agents. Also provided are methods for prophylactically and/or therapeutically immunizing individuals against HBV. The combination vaccine can also be used for particular design vaccines for particular levels of immune responses to HBV challenge.
Patent NZ-714574-A (NZ)
Title: Method and compositions for cellular immunotherapy
Inventor: RIDDELL STANLEY
IPC: C12N15/09
Filed: 2012-03-23
Abstract: An adoptive cellular immunotherapeutic composition containing CD4+ and CD8+ T-lymphocytes that contain a chimeric antigen receptor, wherein the CD8+ lymphocytes are derived from a central memory-enriched CD8+ population
Patent NZ-723969-A (NZ)
Title: In-situ cross-linkable polymeric compositions and methods thereof
Inventor: LANDOLINA JOSEPH A
IPC: C08L5/08
Filed: 2012-11-12
Abstract: Provided is a biocompatible polymeric composition comprising 1) one or more polyanionic polymers, such as alginates or hyaluronates, and 2) one or more polycationic polymers, such as chitosan or DEAE-Dextran. The composition may be useful in the treatment of wounds as the polymers cross link in situ in a wound forming a gel. In a preferred embodiment the composition consists of 0.1 to 5% by weight of sodium alginate, 2 to 25% by weight of chitosan, and water as a solvent.
Patent NZ-729437-A (NZ)
Title: Mask system
Inventor: BARLOW ADAM
IPC: A61M16/08
Filed: 2011-08-31
Abstract: Disclosed is a CPAP patient interface used for treatment of sleep disordered breathing with improved comfort, the patient interface comprising a cushion region adapted to form a seal with a patient’s face, at least a portion of the cushion region including textile that is coated or sealed to create an air impermeable seal; a central portion provided to the cushion region and defining a breathing chamber, the central portion including textile; and a headgear region including straps adapted to maintain the cushion region in position on the patient’s face. The cushion region includes one or more selected regions that are coated to create air impermeable regions for sealing, the cushion region includes a sealing surface along its perimeter, the sealing surface having a convex shape which is adapted to form a seal with a patient’s face, and one or more regions that are uncoated to create air permeable regions for venting. The central portion is laminated or sealed. The headgear region includes textile in a one-piece construction with the central portion. A tube connector is provided to the cushion region and adapted to communicate with air delivery tubing.
Patent NZ-734324-A (NZ)
Title: Compositions and methods for the treatment of inflammation and pain
Inventor: KANDULA MAHESHA
IPC: C07C229/36
Filed: 2015-05-07
Abstract: The invention relates to a compound of Formula V or a pharmaceutically acceptable hydrate, solvate, prodrug, enantiomer, or stereoisomer thereof. The invention also relates to a pharmaceutical composition comprising the compound of Formula V. The invention further relates to use of the compound of Formula V in the manufacture of a pharmaceutical composition for treating inflammation-mediated pain.
Patent NZ-737662-A (NZ)
Title: Cell
Inventor: KONG KHAI
IPC: C12N15/63
Filed: 2016-05-31
Abstract: The present invention relates to a cell which comprises a chimeric antigen receptor (CAR) and a signal transduction modifying protein, selected from one of the following: (i) a truncated protein which comprises an SH2 domain from a protein which binds a phosphorylated immunoreceptor tyrosine-based activation motif (ITAM), but lacks a kinase domain; (ii) a truncated protein which comprises an SH2 domain from a protein which binds a phosphorylated immunoreceptor tyrosine-based inhibition motif (ITIM) but lacks a phosphatase domain; (iii) a fusion protein which comprises (a) an SH2 domain from a protein which binds a phosphorylated immunoreceptor tyrosine-based activation motif (ITAM) or from a protein which binds a phosphorylated immunoreceptor tyrosine-based inhibition motif (ITIM); and (ii) a heterologous domain. In a particular embodiment the invention related to a T cell which comprises a CAR and a truncated protein which comprises: i) A PTPN6 SH2 domain which binds a phosphorylated ITIM but lacks a PTPN6 phosphatase domain; or a SHP-2 SH2 domain which binds a phosphorylated ITIM but lacks a SHP-2 phosphatase domain.
Patent NZ-742429-A (NZ)
Title: Processing biomass
Inventor: MEDOFF MARSHALL
IPC: C10G32/04
Filed: 2013-10-10
Abstract: Methods and systems are described for processing cellulosic and lignocellulosic materials into useful intermediates and products, such as energy and fuels. For example, conveying systems, such as highly efficient vibratory conveyors, are described for the processing of the cellulosic and lignocellulosic materials. Provided herein is an apparatus for producing a treated biomass material, that includes an ionizing radiation source.
Patent NZ-747834-A (NZ)
Title: Metasurfaces with asymmetric gratings for redirecting light and methods for fabricating
Inventor: HILAIRE PIERRE ST
IPC: B44C1/22
Filed: 2017-05-05
Abstract: An optical system comprises an optically transmissive substrate comprising a metasurface which comprises a grating comprising a plurality of unit cells. Each unit cell comprises a laterally-elongated first nanobeam having a first width; and a laterally-elongated second nanobeam spaced apart from the first nanobeam by a gap, the second nanobeam having a second width larger than the first width. A pitch of the unit cells is 10 nm to 1 μm. The heights of the first and the second nanobeams are: 10 nm to 450 nm. When forming part of a display, the metasurface and associated nanobeams may be used to redirect the light so that different optical imagery is possible.
Patent NZ-751082-A (NZ)
Title: Compositions and methods for immunotherapy
Inventor: BRENTJENS RENIER
IPC: A61K35/12
Filed: 2014-02-26
Abstract: The present invention provides for methods and compositions for enhancing the immune response toward cancers and pathogens. It relates to immunoresponsive cells bearing antigen receptors, which can be chimeric antigen receptors (CARs), which express introduced ligands for immunomodulatory molecules. In particular embodiments, engineered immunoresponsive cells are antigen-directed and resist immunosuppression and/or have enhanced immune-activating properties.
Patent NZ-752578-A (NZ)
Title: Coordinated sizer-punch tool for articular cartilage repair
Inventor: WILLIAMS RILEY
IPC: A61B17/56
Filed: 2017-10-16
Abstract: A tool system for the repair of joint articular cartilage defects is disclosed. The tool system may include a non-trephine cutting tool, having a handle coupled to a movable support and a cutter section, coupled to the handle. The cutter section has a closed geometric peripheral shape sized to surround a lesion in cartilage of an articular joint. The cutter section also has a cutting edge that is sufficiently sharp to cut, by the application of force normal to the cutting edge, through cartilage surrounding a joint articular cartilage lesion from a repair site while having insubstantial effect on subchondral bone underlying the cartilage surrounding the joint articular lesion cartilage being cut, and a cartilage repair patch.
Patent NZ-754655-A (NZ)
Title: Method for preparing an iced tea or coffee beverage
Inventor: DEES HENDRIK JOHAN
IPC: A23G9/52
Filed: 2017-12-27
Abstract: The present invention provides a method for preparing an ice-containing tea or coffee beverage, the method comprising: (i) providing a beverage liquor containing soluble tea or coffee solids, and a freezing-point suppressant; (ii) aerating the beverage liquor by the addition of a gas; (iii) flowing the aerated beverage liquor through a refrigeration system to cool the aerated beverage liquor and to thereby form a plurality of ice crystals within the aerated beverage liquor; and (iv) dispensing the cooled aerated beverage liquor as an ice-containing tea or coffee beverage.
Patent NZ-758522-A (NZ)
Title: Systems and methods for identity atomization and usage
Inventor: DIVITA BARTHOLOMEW
IPC: G06Q20/40
Filed: 2018-06-13
Abstract: A method of providing identity information may include: receiving, from a transaction system, a request regarding a transaction; retrieving at least one rule defining a compliant identity based on a type of the transaction, the at least one rule identifying a plurality of identity attributes; retrieving an identity index map including a list of pointers to available identity components; selecting pointers from the identity index map pointing to identity components corresponding to the plurality of identity attributes; outputting, to the transaction system, the compliant identity including information corresponding to each of the identity components, the information including for each identity component at least one of: the selected pointers to the identity component, or the identity component. A method of providing identity information also may include: receiving identity information; processing the received identity information to identity an identity type; retrieving a stored identity type definition for the identity type; atomizing the identity information into a plurality of identity components based on a plurality of attributes defined for the identity type; distributing the identity components to a plurality of different storage locations; and generating and storing an index including pointers to the identity components.
Patent NZ-772266-A (NZ)
Title: Pegylated tetanus neurotoxins and treatment of hypotonia
Inventor: MCLEAN THOMAS
IPC: C07K14/33
Filed: 2019-07-30
Abstract: The invention relates to a composition comprising a first PEGylated tetanus neurotoxin (PEG-TeNT) comprising tetanus neurotoxin (TeNT) conjugated to polyethylene glycol (PEG) and a second TeNT. The invention also relates to various PEG-TeNTs. The invention also relates to a method of treating hypotonia using the composition or various PEG-TeNTs, and a kit comprising the composition or various PEG-TeNTs. In one embodiment, the hypotonia is obstructive sleep apnoea.
Patent NZ-773985-A (NZ)
Title: Downhole release apparatus
Inventor: MASSEY JAMES P
IPC: E21B17/02
Filed: 2019-09-27
Abstract: A release tool included in a tool string stuck within a wellbore may be operated to disconnect a free portion of the tool string from a stuck portion of the tool string. The release tool may be operated by applying tension to the stuck tool string from a wellsite surface. However, the release tool limits the amount of tension that can be applied to the stuck tool string in an attempt to first free the entire tool string before operating the release tool to disconnect the free portion of the tool string from the stuck portion of the tool string. The present disclosure is directed to a downhole release apparatus having a first connector sub connectable with a first portion of a tool string and a second connector sub connectable with a second portion of the tool string. The first connector sub may include a housing, a first latching member, and a blocking member. The second connector sub may include a second latching member. The first and second latching members may engage thereby connecting the first and second connector subs. The blocking member may be movable from a first position in which the blocking member prevents the first and second latching members from disengaging to a second position in which the blocking member permits the first and second latching members to disengage thereby permitting the first and second connector subs to disconnect. When the downhole release apparatus is connected within a tool string stuck within a wellbore, relative movement between the housing and first latching member may facilitate movement of the blocking member from the first position to the second position to permit the first and second connector subs to disconnect and thereby permit a free first portion of the tool string to be disconnected from a stuck second portion of the tool string and retrieved to the wellsite surface.
Patent NZ-781366-A (NZ)
Title: Heteroaryl derivative, method for producing same, and pharmaceutical composition comprising same as effective component
Inventor: LEE YOUN HO
IPC: C07D491/08
Filed: 2020-03-19
Abstract: The present invention relates to a 6-(isooxazolidin-2-yl)-N-phenylpyrimidin-4-amine derivative, and a pharmaceutical composition for preventing or treating cancer comprising the compound as an effective component. The compound exhibits high inhibitory activity against an epidermal growth factor receptor (EGFR) variant, or wild-type or variants of one or more of ERBB2 and ERBB4, and thus may be usefully used in the treatment of cancers in which same are expressed. In particular, the compound exhibits excellent inhibitory activity on proliferation of lung cancer cell lines, and thus can be usefully used in the treatment of lung cancer.
Patent PT-100103-A (PT)
Inventor: MITCHELL ROBERT WILLIAM
IPC: A01N25/30
Filed: 1992-02-07
Abstract: A composition of glyphosate comprising a glyphosate herbicide and a surface active component characterized in that the said surface active component is the combination of a sorbitan fatty acid ester and a surfactant chemically different from said sorbitan fatty acid ester.
Patent RO-91352-A (RO)
Inventor: ZOLSE GERHARD
IPC: C07C275/70
Filed: 1985-03-15
Abstract: 1. Claims (for the Contracting States : BE, CH, DE, FR, GB, IT, LI, LU, NL, SE) S(-)-3-[3-acetyl-4-(3-tert.butylamino-2-hydroxypropoxy) phenyl]-1,1-diethylurea (S(-)-celiprolol) and its pharmaceutically acceptable acid addition salts. 1. Claims (for the Contracting State AT) Process for the preparation of S(-)-3-[3-acetyl-4-(3-tert.butylamino-2-hydroxypropoxy) phenyl]-1,1-diethylurea (S(-)-celiprolol) and its pharmaceutically acceptable acid addition salts, characterised in that a) the racemate of the formula  see diagramm : EP0155518,P10,F1  in the form of the base is reacted with an enantiomer of a chiral resolving acid in a suitable organic solvent, the mixture of the two diastereomeric salts formed in this manner is separated by fractional crystallisation, and, after separating each diastereomeric salt which contains the laevorotatory enantiomer of the compound of the formula I in the S configuration, is reconverted into the free base or a pharmaceutically acceptable addition salt and the resolving acid is recovered, or b) S(+)-3-[3-acetyl-4-(2,3-epoxypropoxy)-phenyl]- 1,1-diethylurea of the formula  see diagramm : EP0155518,P10,F2  is reacted with tertiary butylamine in the presence of water at room temperature or with gentle heating to a maximum of 40 degrees C, and then the laevorotatory enantiomer of the compound of the formula I thus obtained is converted as required into a pharmaceutically acceptable addition salt.
Patent RU-94000950-A (RU)
Inventor: NOSENKO V F
IPC: A01G25/02
Filed: 1994-01-06
Abstract: FIELD: agriculture. SUBSTANCE: apparatus has irrigation pipelines with water discharge micropipes, accumulating vessel, siphon and starting mechanism with collector, tube-type water level detector and breather pipe. Siphon is formed as bundle of pipes and collector has pipes with perforated walls. Collector pipes are communicated at their one ends with discharge part of siphon and at their other ends with irrigation pipelines. EFFECT: simplified construction and enhanced reliability in operation.
Patent RU-94009073-A (RU)
Inventor: OBUKHOV I A
IPC: A61B17/56
Filed: 1994-03-14
Abstract: FIELD: medicine. SUBSTANCE: method involves introducing and fixing plate bent in correspondence with the articulation surface of the injured bone into the joint by means of apparatus. The plate compresses and fixes the fractured bone fragments. EFFECT: enhanced effectiveness of treatment.
Patent RU-94021641-A (RU)
Inventor: GARET DZHEJMS DZHONS
IPC: H03K19/177
Filed: 1994-06-17
Abstract: FIELD: electronics. SUBSTANCE: circuit has part with number of logical gates in discrete mounting points or cells which determine matrix lattice of elements. Matrix lattice of elements is divided into zones, each of which contains matrix lattice of elements, device for connection of each zone and hierarchical structure of routing resources, which has (i) global connection parts (G, X), which have switched connections to device for connection of each zone; (ii) middle connection parts (M), which run from connecting device and are connected to at least several connecting cells in zone; (iii) local routes for direct connection, which contain device for limited signal relay. In addition device has matrix lattice of core cells, each of which provides first simple function together with at least one additional function. At least two different additional functions are provided. Core cells are combined in plates containing matrix lattice of core cells, which is lesser than overall matrix and each plate in it provides at least one of any different additional functions. Plates of core cells are located for uniform covering of matrix. Best variant involves four cells for plate. Functions to be provided are OR circuit, XOR circuit, D flip-flop and lock function. Proposed features are to be joined in order to achieve best design of semiconductor circuit with variable configuration. EFFECT: increased functional capabilities.