baber/WOPTO huggingface dataset:
Patent NZ-580727-A (NZ)
Title: Low temperature container with a neck suspended double-walled insulating bulb within a package
Inventor: COGNARD ERIC
IPC: A01N1/02
Filed: 2008-03-25
Abstract: A device (10) for transporting and/or storing products such as liquid Nitrogen is disclosed. The device having an external packaging structure (14) comprising walls defining an internal volume (16) within which is a double-walled insulating bulb (12). The body of the bulb (12) is formed by an outer wall (34) and an inner wall (36) defining an internal volume (38). The bulb (12) also has an upper neck (40) defining an upper filling opening (42). A bulb supporting means (46) with an attachment means (48) suspends the bulb (12) vertically by its neck (40) in such a way that the bulb (12) hangs inside the internal volume (16) defined by the packaging structure (14, 18, 22), with no contact between the outer wall (34) of the bulb (12) and the walls (24, 22) of the packaging structure (14). The means (46) for the suspended support of the bulb (12) consists of at least one (20) of the walls of the packaging (14).
Patent NZ-581251-A (NZ)
Title: Single-stranded cyclic rna, and method for production thereof
Inventor: ABE HIROSHI
IPC: A61P43/00
Filed: 2008-05-09
Abstract: Provided is a single-chain circular RNA having a sustained or slow-releasing RNA interference effect, wherein the single-chain circular RNA comprises a sense strand sequence, an antisense strand sequence complementary to the sense strand sequence, identical or different two loop sequences between the sense strand and the antisense strand, connecting both strands, wherein the sense strand and the antisense strand are paired to form a stem, and wherein each, of the two loops is 6 to 9 nucleotides in length. The RNAs can be used to suppress gene activity in vivo and show an extended effect.
Patent NZ-581395-A (NZ)
Title: Single-chain fc (scfc) regions, binding polypeptides comprising same, and methods related thereto
Inventor: FARRINGTON GRAHAM K
IPC: A61P29/00
Filed: 2008-05-14
Abstract: Disclosed is isolated binding polypeptide comprising (i) a first binding site, and (ii) an Fc region consisting of a single polypeptide chain encoded in a single contiguous genetic sequence wherein: a. said Fc region is a heteromeric Fc region and comprises at least two Fc moieties; b. said Fc region is fused via a polypeptide linker sequence interposed between said at least two Fc moieties; c. said Fc region imparts at least one effector function to said binding polypeptide; and d. said at least two Fc moieties are folded intramolecularly within said Fc region to form said Fc region.
Patent NZ-587835-A (NZ)
Title: Oil formulation with cyclopropene and encapsulating agent
Inventor: KOSTANSEK EDWARD CHARLES
IPC: A01N25/04
Filed: 2008-07-09
Abstract: Disclosed is a composition comprising an oil medium, wherein solid particles are suspended in said oil medium, wherein said solid particles comprise cyclopropene and molecular encapsulating agent that encapsulates said cyclopropene or portion of said cyclopropene, and wherein said solid particles have median size, as measured by the largest dimension, of 50 micrometer or less, wherein said cyclopropene is any compound of the formula specified in the specification wherein said oil is a compound that is liquid at 25 degrees C and one atmosphere pressure; that has boiling point at one atmosphere pressure of 30 degrees C or higher; and that is not water, surfactant, or dispersant; and wherein the continuous medium of said composition is said oil medium.
Patent NZ-590563-A (NZ)
Title: Diagnostic antibody assay
Inventor: DEMUTH HANS-ULRICH
IPC: A61K39/00
Filed: 2009-07-10
Abstract: Antibody, characterised in that it binds to A~ peptides or variants thereof, wherein said A~ peptides or variants thereof are selected from the group consisting of: pGlu-Aâ3-38 pGlu-Aâ3-40 pGlu-Aâ3-42, and pGlu-Aâ3-x variants, wherein x is an integer between 10 and 42; and wherein the variable part of the light chain of said antibody has a nucleotide sequence selected from SEQ ID NOs: 49, 53, 57 and 61, or an amino acid sequence selected from SEQ ID NOs: 50, 54, 58, and 62; and wherein the variable part of the heavy chain of said antibody has a nucleotide sequence selected from SEQ ID NOs: 51, 55, 59 and 63, or an amino acid sequence selected from SEQ ID NOs: 52, 56, 60 and 64.
Patent NZ-591439-A (NZ)
Title: pCAGGS VECTOR COMPRISING AN 829 BASE PAIR DELETION IN THE CHICKEN-BETA ACTIN INTRON WHICH RESULTS IN ENHANCED EXPRESSION OF A GENE OF INTEREST
Inventor: KOBINGER GARY
IPC: C07K14/08
Filed: 2009-08-07
Abstract: Disclosed is a pCAGGS vector with an optimized CAG promoter sequence consisting of a nucleotide sequence as set forth in SEQ ID No.1 . Also disclosed is A CAG promoter sequence having a nucleotide sequence as set forth in SEQ ID No. 1 operably linked to a nucleic acid sequence comprising a Kozak sequence and a nucleic acid sequence encoding a codon-optimized Ebola virus glycoprotein as set forth in SEQ ID No. 2.
Patent NZ-591602-A (NZ)
Title: Bispecific antibodies specifically binding to human vascular endothelial growth factor and human angiopoietin-2
Inventor: BAEHNER MONIKA
IPC: A61K39/395
Filed: 2009-10-07
Abstract: Disclosed is a bispecific antibody specifically binding to human vascular endothelial growth factor (VEGF) and human angiopoietin-2 (ANG-2) comprising a first antigen-binding site that specifically binds to human VEGF and a second antigen-binding site that specifically binds to human ANG. Also disclosed is the use of the antibody for the manufacture of a medicament for the treatment of vascular diseases.
Patent NZ-593150-A (NZ)
Title: Substituted tetrahydropyran spiro pyrrolidinone and piperidinone, preparation and therapeutic use thereof
Inventor: GAO ZHONGLI
IPC: A61K31/407
Filed: 2009-12-04
Abstract: Disclosed are compounds of formula (I) and methods for their preparation. The compounds are useful as H3 receptor antagonists / inverse agonists. A specific example is 2-[2-methyl-4-((2S,3'S)-2-methyl-[1,3']bipyrrolidinyl-1'-yl)-phenyl]-8-oxa-2-azaspiro[4.5]decan-1-one; The compounds can be used to modulate H3 receptor function and thus treat cognitive impairment associated with schizophrenia (CIAS), anxiety disorders such as generalized anxiety, panic disorder and post-traumatic stress disorder, major depressive disorder,dementia of Alzheimer type (OAT), cognitive deficits related to neurological diseases chosen from Alzheimer, Parkinson or Huntington, age related cognitive impairment, mild cognitive impairment, vascular dementia, Lewis Body dementia, cognition associated with cognitive deficits, sleep related disorders, attention deficit hyperactivity disorder and depression, and obesity.
Patent NZ-602624-A (NZ)
Title: Drive system
Inventor: HARRIS E MARK
IPC: F16H1/28
Filed: 2011-03-30
Abstract: 602624 Disclosed is a drive unit that is movable between an unfired and a fired position. The drive unit comprises a handle member (see 12, figure 2), a first drive gear (47) having a first axis of rotation, and a second drive gear (40), engaged to the first drive gear at a mesh point, and having a second axis of rotation. The first drive gear is a spiral radius gear, wherein the radius of the gear increases across its arc of rotation. The second drive gear is a pinion quarter gear, wherein the radius at a first end of the pinion quarter gear is greater at a first end of its arc than at a second end of its arc. The handle is engaged to the first drive gear. The first and second gears mesh to form a stepless gear mechanism, whereby upon rotation of the handle the gear ratio between the first and second gears changes as the handle is moved from the unfired position (see figure 11) to the fired position (see figure 10). As the handle member moves from the unfired position to the fired position, the mesh point of the first and second gears moves with respect to the axes of rotation. The output torque of the second drive gear also decreases when the handle member moves from the unfired position to the fired position. A food processing device (see 10, figure 1) comprising such a drive unit is also disclosed.
Patent NZ-614427-A (NZ)
Title: Use of inhibitors of egfr-family receptors in the treatment of hormone refractory breast cancers
Inventor: GARCIA GABRIELA
IPC: C07K16/40
Filed: 2012-03-12
Abstract: Disclosed is the use of an antibody that inhibits heregulin binding to ErbB2/ErbB3 heterodimer for manufacture of a medicament for treating a malignant tumour in a human patient, wherein the patient has been treated for malignancy with an anti-estrogen therapy and has become resistant to such therapy, wherein the malignant tumour, by analysis of a tumour biopsy taken from the patent after the patient has become resistant, is estrogen receptor positive and expresses HER2, wherein the antibody inhibits heregulin-mediated activation of estrogen receptors in malignant tumour cells, which activation comprises phosphorylation of estrogen receptors, wherein the antibody is formulated for administration at a dosage that yields a concentration of the antibody in the patient’s bloodstream that is a sufficient concentration to inhibit heregulin-induced estrogen receptor phosphorylation in MCF7 cells in vitro by at least 20%, at least 30%, at least 40%, at least 50%, at least 60%, or at least 70%, and wherein the antibody comprises, VH CDR1, 2 and 3 sequences as shown in SEQ ID NOs: 3-5, respectively, and, VL CDR1, 2 and 3 sequences as shown in SEQ ID NOs: 6-8, respectively.
Patent NZ-621859-A (NZ)
Title: Thermostabilization of proteins
Inventor: WOODS JAMES H
IPC: A61K38/46
Filed: 2008-07-10
Abstract: Disclosed is a method for identifying a thermostabilization compound, the method comprising: measuring thermostability of a cocaine esterase (CocE) at a first high temperature selected from the group consisting of 34°C, about 37°C, 40°C, 42.5°C, 45°C, greater than about 50°C, and greater than about 95°C; combining the CocE and a candidate compound, the candidate compound present at a concentration of less than about 1mM; measuring thermostability of the CocE in combination with the candidate compound at the high temperature; determining whether the candidate compound increases thermostability of the CocE.
Patent NZ-622105-A (NZ)
Title: Automated system and methods for separating and singulating plant embryos
Inventor: SWANDA ANTHONY P
IPC: B07C5/04
Filed: 2012-12-18
Abstract: An automated system and methods for separating and grading plant embryos is disclosed. The process of separating and grading plant embryos is expedited by use of this system. A series of stations are disclosed for the separation (200), grading (300, 70, 74), drying (400) and storage (500) of plant embryos grown in embryogenic suspensor mass. The embryos can be moved between each station in any order by a programmable robotic arm (114, 120). Its use in silviculture is specifically disclosed.
Patent NZ-623098-A (NZ)
Title: Substituted benzylindazoles for use as bub1 kinase inhibitors in the treatment of hyperproliferative diseases.
Inventor: BRIEM HANS
IPC: C07D498/04
Filed: 2012-10-04
Abstract: Provided are pyrimidine substituted benzylindazoles of the general formula (I), wherein the variables are as defined in the specification. Examples of the compounds include 2-[1-(6-chloro-2-fluoro-3-methylbenzyl)-1H-indazol-3-yl]-5-methoxy-N-(pyridin-4-yl)pyrimidin-4-amine and 2-[1-(4-ethoxy-2,6-difluorobenzyl)-4-methyl-1H-indazol-3-yl]-5-methoxy-N-(pyridin-4-yl)pyrimidin-4-amine. The compounds are inhibitors of Bub1 kinase. The compounds may be useful in the treatment of cancer.
Patent NZ-623833-A (NZ)
Title: Touch dimmer lighting control
Inventor: O’DRISCOLL DAVID
IPC: H05B37/02
Filed: 2012-10-12
Abstract: Disclosed is a touch panel device (12) for a dimmer lighting control system (10). The device (12) comprising a touch sensitive surface (14) capable of detecting movement of a finger or fingers in first and second directions, and a processing means for generating first and second control signals respectively based on this detection. In use, the balance of the load between first and second light circuits and a total light output of both light circuits can be controlled with the same touch panel device (12).
Patent NZ-624105-A (NZ)
Title: A method to wash greasy wool, a method to separate lanolin from the said greasy wool, wool and lanolin obtainable by these methods
Inventor: REUTELINGSPERGER CHRISTIAAN MATHIAS HUBERTUS GERAR
IPC: D01C3/00
Filed: 2012-10-05
Abstract: Disclosed herein is a method to wash wool containing lanolin and impurities comprising providing a volume of an aqueous liquid at a temperature below a melting temperature of the lanolin, soaking the wool in the volume of the liquid, creating air bubbles in the liquid and allowing the air bubbles to pass through the wool to attach the impurities, and removing the air bubbles and attached impurities from the said volume. The invention also pertains to a method to separate lanolin from wool containing lanolin and impurities and to wool and lanolin obtainable by these methods.
Patent NZ-625337-A (NZ)
Title: Anticoagulant reversal agents
Inventor: STEINER SOLOMON S
IPC: C07D241/04
Filed: 2012-11-29
Abstract: Provided are compounds of the general formula (I), wherein the variables are as defined in the specification. In embodiments the compounds are represented by the general formulae (II) and (IV). Particularly preferred are piperazine-diarginine derivative compounds such as 2-Amino-5-guanidino-pentanoic acid (3-{ 4-[3-(2-amino-5-guanidinopentanoylamino)-propyl]-piperazin-1-yl} -propyl)-amide and 2-Amino-5-guanidino-pentanoic acid { 5-[(2-amino-5-guanidinopentanoylamino)-methyl]-piperazin-2-ylmethyl} -amide. The compounds are useful for reversing the anticoagulant effects of coagulation inhibitors.
Patent NZ-626434-A (NZ)
Title: A hydroelectric turbine system
Inventor: IVES JAMES
IPC: F03B17/06
Filed: 2012-12-19
Abstract: Disclosed is a hydroelectric turbine system operational method comprising the steps of: deploying a hydroelectric turbine on a seabed within a tidal body of water; permitting the turbine to rotate and generate electrical power in response to the tidal flow of water past the turbine; and absorbing the electrical power into a load bank electrically connected to the turbine. The load bank is mounted to the hydroelectric turbine system. The load bank may be used to dissipate energy when the turbine is not connected to the grid.
Patent NZ-703319-A (NZ)
Title: Paliperidone implant formulation
Inventor: GUTIERRO ADURIZ IBON
IPC: A61K47/34
Filed: 2013-05-31
Abstract: An injectable intramuscular depot composition suitable for forming an in situ solid implant in a body, comprising a drug which is paliperidone and/or its pharmaceutical acceptable salts in any combination thereof, a biocompatible copolymer based on lactic and glycolic acid having a monomer ratio of lactic to glycolic acid in the range from 50:50 and a DMSO solvent, wherein the composition releases the drug with an immediate onset of action and continuously for at least 8 weeks and wherein the composition has a pharmacokinetic profile in vivo suitable for the formulation to be administered each 8 weeks or even longer periods.
Patent NZ-711343-A (NZ)
Title: Sodium salt of (2s, 5r)-6-benzyloxy-7-oxo-1,6-diaza-bicyclo [3.2.1 ] octane-2-carboxylic acid and its preparation
Inventor: BHAVSAR SATISH
IPC: C07D471/08
Filed: 2013-10-10
Abstract: Sodium salt of (2S, 5R)-6-benzyloxy-7-oxo-1,6-diaza-bicyclo[3.2.1]octane-2-carboxylic acid (Formula I) and a process for its preparation is disclosed.
Patent NZ-724847-A (NZ)
Title: Gas removal system
Inventor: Garry Hilton
IPC: F23J11/02
Filed: 2016-09-30
Abstract: A gas exhaust and dispersion system addressing the need for flexibility between the a gas chamber 62 and a dispersion device 20, and delivering exhaust to a satisfactory height or distance from the dispersion device 20, including: a gas chamber 62, sealed to the exterior environment 66; an exhaust device including: an inlet port 40a adapted to be connected to the gas chamber 62 through which chamber gas is extracted from the gas chamber 62; a relief port 40b adapted to be connected to the gas chamber 62 and spaced from the inlet port 40a; a relief port valve 52b to stop, slow or allow the flow of gas through the relief port 40b; a flexible duct 56 adapted to be connected to the inlet port 40a; an axial fan 54 installed at any point along the flexible duct 56 and adapted to create a positive pressure in the flexible duct 56; and a flexible duct valve 52a installed at any point along the flexible duct 56 and adapted to stop, slow or allow the flow of gas through the flexible duct 56.
Patent NZ-726410-A (NZ)
Title: Device for unilateral analysis of products by turning and automatic sorting and conveying device incorporating same
Inventor: BLANC PHILIPPE
IPC: G01N21/88
Filed: 2015-04-28
Abstract: The invention relates to a device for unilateral analysis - notably optical - of products. It comprises a product turning device comprising two series (18, 20) of levers (19, 21) in opposition borne by at least one conveyor. The Conveyor is continuously driven in a longitudinal direction with respect to a fixed structure, and a device (34, 37) commanding the pivoting of the levers (19, 21) which is designed to cause the products to be turned over in a turning zone (35). The turning zone being between two successive unilateral analysis work stations in the longitudinal direction of the conveyor. In the turning zone, several levers (19, 21) of one same series are made to pivot by the control device (34, 37) each product being able to be turned over under the effect of the pivoting of several levers (19, 21) of each series.
Patent NZ-730424-A (NZ)
Title: Ventilator aerosol delivery system
Inventor: LEAMON JAMES
IPC: A61M11/04
Filed: 2013-08-21
Abstract: An aerosol delivery system comprises an aerosol generator 230 for producing an aerosol, a continuous positive pressure airway ventilator 300 for producing a pressurized ventilation gas, a splitter 312 for splitting the pressurized ventilation gas into a carrier gas 316 and a ventilation gas 317, a conduit 302 from the ventilator to the splitter and an aerosol transition adapter 100 arranged to combine the aerosol produced by the aerosol generator with the carrier gas from the splitter. The transition adapter divides the carrier gas into a plurality of streams of carrier gas, which are directed to at least partially encircle and to flow in parallel with the aerosol entering the transition adapter, and which form an entrained aerosol 240. An aerosol delivery connector 330 has a port 334 for receiving the entrained aerosol, a port 332 for entry of the ventilation gas, an interface port 336 for delivering the entrained aerosol from the aerosol transition adapter and the ventilation gas from the splitter to a patient through a patient interface 340.
Patent NZ-731226-A (NZ)
Title: Method for modifying power of light adjustable lens
Inventor: GRUBBS ROBERT
IPC: G02C7/06
Filed: 2016-05-20
Abstract: A light adjustable lens (LAL) is an optical device whose refractive properties can be changed after manufacture, such as by adjusting optical power by use of UV irradiation. However, light sources, such as lasers, for conducting UV irradiation may create high irradiances that can cause damage in instances where LALs are implanted into the human eye. Provided herein are systems and methods to modify a refractive property of a LAL by a lens adjustment system that provide improvements in the achieved optical power change and in other optical characteristics. A method for adjusting a LAL in an optical system comprises providing a LAL in an optical system, wherein the LAL comprises photo-polymerizable macromers in a first polymer matrix, providing an ultraviolet light source to generate an ultraviolet light, irradiating the generated ultraviolet light with a light delivery system onto the light adjustable lens with a center wavelength and with a spatial irradiance profile to photo-polymerize a portion of the photo-polymerizable macromers to change a dioptric power of the light adjustable lens by changing a refraction of the LAL over a refraction-change zone, thereby causing a wavefront sag, defined as half of a product of the change of the dioptric power of the optical system and the square of a radius of the refraction-change zone of the LAL, to be within 10% of its maximum over an ultraviolet spectrum, wherein the ultraviolet light source and the light delivery system are configured for irradiating the light adjustable lens with the ultraviolet light having a center wavelength in a range of 370 nm to 390 nm, an average irradiance in a range of 1 mW/cm2 to 50 mW/cm2 and a full width half maximum spectral bandwidth that does not exceed 10 nm. A lens adjustment system is also provided for adjusting a LAL.
Patent NZ-740281-A (NZ)
Title: Steel sheet and enameled product
Inventor: KUSUMI KAZUHISA
IPC: C22C38/60
Filed: 2016-09-12
Abstract: This steel sheet contains, in terms of mass%, up to 0.0060% C, 0.0010-0.050% Si, 0.05-0.50% Mn, 0.005-0.100% P, up to 0.0500% S, 0.0010-0.010% Al, 0.010-0.045% Cu, 0.0250-0.0700% O, and 0.0010-0.0045% N, with the remainder comprising Fe and unavoidable impurities. The steel sheet has a structure which comprises ferrite, and the ferrite located at a sheet-thickness-direction depth corresponding to 1/4 the sheet thickness from a surface of the steel sheet has an average crystal-grain diameter of 20.0 µm or smaller. The structure contains oxides containing Fe and Mn. Among the oxides, the number density of the oxides having diameters larger than 1.0 µm but not larger than 10 µm is 1.0×103-5.0×104grains/mm2, and the number density of the oxides having diameters of 0.1-1.0 µm is 5.0×103grains/mm2or greater.
Patent NZ-751363-A (NZ)
Title: Upgrading process streams
Inventor: MEDOFF MARSHALL
IPC: C12P7/10
Filed: 2014-03-07
Abstract: Biomass (e.g., plant biomass, animal biomass, and municipal waste biomass) is processed to produce useful intermediates and products, such as energy, fuels, foods or materials. Systems, methods and equipment are described for upgrading process streams using electrodialysis or electrodialysis reversal. Many potential lignocellulosic feedstocks are available today, including agricultural residues, woody biomass, municipal waste, oilseeds/cakes and seaweed, to name a few.
Patent NZ-782655-A (NZ)
Title: Headgear for masks
Inventor: DRAVITZKI BRENT JAMES
IPC: A61M16/06
Filed: 2009-12-10
Abstract: A respiratory mask system, comprises a mask with supporting headgear, where the headgear has 2 rigid side portions, each comprising a rigid or semi-rigid material surrounded by firmly attached fabric and does not include foam. The patient contacting side of the fabric covering has a fabric inner surface in direct contact with a first surface of the rigidizing material, and the non-patient contacting side of the fabric covering has a fabric inner surface in direct contact with a second surface of the rigidizing material, the second surface of the rigidizing material being opposite the first surface of the rigidizing material. The headgear can be comfortably fitted to the patients, and is easy to use. The headgear can be manufactured at a lower cost.
Patent PT-100573-A (PT)
Inventor: LEET JULIA ELIZABETH
IPC: A61Q5/06
Filed: 1992-06-05
Abstract: Hair styling agents, and aqueous base hair care compositions containing them, wherein the hair styling agent comprises a water-insoluble hair styling polymer with a volatile, water-insoluble diluent. The water-insoluble hair styling polymer consists essentially of hydrophobic monomer units. These compositions are particularly useful for application to the hair in the form of a rinse-off hair care composition comprising the hair styling agent and an aqueous carrier providing a gel-like rheology.