baber/WOPTO huggingface dataset:
Patent MX-2020012404-A (MX)
Title: Methods of increasing tonic inhibition and treating secondary insomnia.
Inventor: DURING MATTHEW
IPC: A61P25/00
Filed: 2015-06-03
Abstract: Methods of increasing tonic inhibition in a subject in need thereof, for example a subject with Fragile X syndrome or Angelman syndrome are disclosed. Methods of treating secondary insomnia in a subject with a neurodegenerative disease or disorder are also disclosed. The methods can include administering the subject an effective amount of 4,5,6,7- tetrahydroisoxazolo(5,4-c)pyridin-3-ol (THIP) or a derivative thereof, or a pharmaceutically acceptable salt thereof, increase tonic inhibition in neurons of the subject; to increase slow wave sleep (SWS) and/or slow wave activity (SWA), normalize sleep architecture, reduce secondary insomnia, increase non-rapid eye movement (NREM) sleep, increase sleep continuity, enhance delta activity within NREM, increase or improve total sleep time (TST), increase or improve sleep efficiency, reduce total time awake (TAA), reduce number of awakenings (NWA), reduce latency to persistent sleep (LPS), or to reduce wake after sleep onset (WASO), in the subject, or any combination thereof.
Patent MX-2020012829-A (MX)
Title: Cyclopentanone compounds.
Inventor: COULOMB JULIEN
IPC: C11B9/00
Filed: 2019-10-14
Abstract: The present invention relates to the use as perfuming ingredients, e.g. to impart odor notes of the fruity, fruity-exotic types, of cyclopentanone compounds of formula (I) in the form of any one of its stereoisomers or a mixture thereof, and wherein n represents 1 or 2.
Patent MX-2020013562-A (MX)
Title: Portable mixer for hydrating and mixing cementitious mix in a continuous process.
Inventor: SCOTT RICK
IPC: B28C7/06
Filed: 2020-12-11
Abstract: A portable mixer includes a frame, a hopper for receiving therein dry cementitious mix, and a chute rigidly coupled to the hopper that communicates with the hopper via an aperture. The hopper and chute are pivotally coupled to the frame. The portable mixer further includes an auger extending from the hopper into the chute via the aperture, a water supply system configured to apply water to cementitious mix, and a motor coupled to the auger and configured to rotate the auger to mix the dry cementitious mix with the water.
Patent MX-2021013441-A (MX)
Title: An antigen-binding molecule, a pharmaceutical composition, and a method.
Inventor: KOGA HIKARU
IPC: C07K16/18
Filed: 2020-05-14
Abstract: The present invention provides antigen-binding molecules that bind to C1s and comprise a heavy chain variable region, a light chain variable region and an Fc region, wherein (i) the heavy chain variable region and/or the light chain variable region comprise at least one amino acid that can increase the ratio of KD value of the antigen-binding molecule to C1s in acidic pH range to KD value of the antigen-binding molecule to C1s in neutral pH range, KD (acidic pH range)/ KD (neutral pH range), compared to that of the first reference antibody; (ii) the Fc region comprises at least one amino acid that can increase binding ability of the antigen-binding molecule to FcRn in acidic pH range compared to that of the second reference antibody; and (iii) the Fc region comprises at least one amino acid that can increase binding ability of the antigen-binding molecule to FcÎ³ receptor in neutral pH range compared to that of the second reference antibody.
Patent MX-2021013551-A (MX)
Title: Peptides for use in therapy or prophylaxis of herpesviridae-infections.
Inventor: WEHKAMP JAN
IPC: A61K38/08
Filed: 2020-05-08
Abstract: The present invention relates to new peptides the amino acid sequences of which are derived from HD-5, for use in the treatment and/or prevention of Herpesviridae infections, in particular for treating and/or preventing a Betaherpesviridae infection, such as a HCMV-infection.
Patent MX-2022000092-A (MX)
Title: Improving attachments in a network.
Inventor: BHUTANI ANKIT
IPC: H04W4/70
Filed: 2020-06-20
Abstract: A control device may communicate messages with devices in a network through a parent device, and receive messages from auxiliary parent devices. The control device may store a respective communication metric associated with each of the parent device and the one or more auxiliary parent devices. The control device may set an auxiliary parent device of the one or more auxiliary parent devices as the parent device of the control device, e.g., when a respective communication metric of the auxiliary parent device determined to be set as the parent device indicates a stronger communication link than the parent device. The control device may determine that the respective communication metric of the auxiliary parent device indicates a stronger potential communication link than the parent device when the average received signal strength indicator of auxiliary parent device is greater than the average received signal strength indicator of the parent device.
Patent MX-2022002856-A (MX)
Title: An anticancer combination of chidamide and celecoxib.
Inventor: CHEN Jia- Shiong
IPC: A61K31/4406
Filed: 2019-09-11
Abstract: The present invention provides a combination of a histone deacetylase (HDAC) inhibitor, chidamide in an acidic salt form, and a nonsteroidal anti-inflammatory drugs (NSAIDs), celecoxib in a basic salt form. The present invention also provides methods which significantly regulate tumor microenvironment and therefore dramatically improve anti-cancer activity.
Patent MX-2022007046-A (MX)
Title: Methods of controlling or preventing infestation of plants by a phytopathogenic microorganism of the genus macrophomina spp.
Inventor: HAMILL JON
IPC: C07D213/81
Filed: 2020-12-03
Abstract: The present invention relates to methods for controlling or preventing infestation of a plant by a phytopathogenic microorganism of the genus macrophomina spp., comprising applying to a crop of plants, the locus thereof, or propagation material thereof, a compound according to formula (I), wherein R1, R2, R3, R4, R5, Y, A, B are as defined herein.
Patent MX-2022007833-A (MX)
Title: New mesothelin specific chimeric antigen receptors (car) for solid tumors cancer immunotherapy.
Inventor: SCHIFFER-MANNIOUI CÉCILE
IPC: C07K14/725
Filed: 2020-12-22
Abstract: The present invention relates to engineered immune cells expressing new mesothelin (MLSN) specific chimeric antigen receptors (anti-mesothelin CAR) and their use in the treatment of solid tumors, particularly suited for allogeneic cell immunotherapy.
Patent MX-2022010442-A (MX)
Title: Potassium salt of 2-[(4s)-8-fluoro-2-[4-(3-methoxyphenyl)p iperazin-1-yl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]-4h -quinazolin-4-yl]acetic acid.
Inventor: BUSCHMANN HELMUT
IPC: A61P31/22
Filed: 2021-03-01
Abstract: The present invention relates to potassium salt of 2-[(4S)-8-fluoro-2-[4-(3-methoxyphenyl)- piperazin-1-yl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]-4H-quin azolin-4-yl]acetic acid and solvates thereof. The invention further relates to methods of preparation of said potassium salt of 2-[(4S)-8-fluoro-2-[4-(3-methoxyphenyl)piperazin-1-yl]-3-[2-met hoxy-5-(trifluoromethyl)- phenyl]-4H-quinazolin-4-yl]acetic acid or solvates thereof as well as pharmaceutical compositions comprising said salt.
Patent MX-2022010512-A (MX)
Title: Bcl-2 protein inhibitors.
Inventor: HUANG PETER QINHUA
IPC: A61P35/00
Filed: 2021-04-26
Abstract: Various Bcl-2 protein inhibitors are described, along with methods of using them to treat conditions characterized by excessive cellular proliferation, such as cancer and tumors. In various embodiments the Bcl-2 protein inhibitors are compounds or pharmaceutically acceptable salts of the following Formula (I), where the variables in Formula (I) are defined herein. (I).
Patent MX-2022011167-A (MX)
Title: Methods for enhancing mucosal innate immune responses to and/or detection of pathogens using human milk oligosaccharides.
Inventor: BUCK RACHAEL
IPC: A23L33/10
Filed: 2016-10-05
Abstract: A method for enhancing an individual's mucosal innate immune response to pathogens is disclosed. The method includes a step of administering a nutritional composition to the individual. The nutritional composition includes about 0.05 to about 0.5 mg/mL 2'-fucosyllactose (2'-FL), about 0.05 to about 0.5 mg/mL lacto-N- neotetraose (LNnT), or a combination of both. Also disclosed is a method for enhancing an individual's mucosal innate immune detection of pathogens. The method includes a step of administering a nutritional composition to the individual. The nutritional composition includes a neutral human milk oligosaccharide.
Patent MX-2022012315-A (MX)
Title: Geolocation compliance for a mobile workforce.
Inventor: DEGENEFFE MIKE
IPC: G06Q10/00
Filed: 2018-05-14
Abstract: A system and method that uses geo-location and a rules engine to facilitate compliance to federal, state, and local regulations as well as company policies across different jurisdictions that may have different compliance regulations. A mobile workforce may use the techniques herein to manage work assignments, report activities, and to manage and track time. This technology may be used, e.g., in the transportation industry, but is not limited to this industry.
Patent MX-2022014583-A (MX)
Title: Power switch enclosure.
Inventor: CARBONE CHRISTOPHER A
IPC: H01H71/04
Filed: 2017-07-03
Abstract: A power switch including a contact configured to selectively electrically connect a line input to a load output, a switch configured to selectively control the contract, and an indicator. The contact has a closed position in which the line input is electrically connected to the load output, and an open position in which the line input is not electrically connected to the load output. The switch has an on position wherein the contact is controlled to be in the closed position, and an off position wherein the contact is controlled to be in the open position. The indicator provides a normal on status, a normal off status, and an error on status.
Patent MX-2022016330-A (MX)
Title: Computer node optical free space interconnection.
Inventor: BELADY CHRISTIAN L
IPC: H04B10/114
Filed: 2021-05-05
Abstract: A system for using free-space optics to interconnect a plurality of computing nodes can include a plurality of optical transceivers that facilitate free-space optical communications among the plurality of computing nodes. The system may ensure a line of sight between the plurality of computing nodes and the optical transceivers to facilitate the free-space optical communications. The line of sight may be preserved by the position or placement of the computing nodes in the system. The position or placement of the computing nodes may be achieved by using different shaped enclosures for holding the computing nodes.
Patent MX-NL03000049-A (MX)
Title: Constructive system based on structural connectors for prefabricated panels.
Inventor: JAVIER MARTINEZ DIRCIO
IPC: E04B1/61
Filed: 2003-12-11
Abstract: The present invention consists in a system of prefabricated structural connectors, which due to the construction and utilization thereof are useful in a constructive system that comprises the attachment of a plurality of prefabricated panels. Said panels are assembled therebetween by a plurality of steel plate structural connectors and connecting shoes, as well as fastening and adjusting elements. The aforementioned elements work together so as to absorb, resist and channel the movements generated in the structural node where the same are located.
Patent MX-PA00001206-A (MX)
Title: Process for producing purine nucleotides.
Inventor: YUTAKA TAKANO
IPC: C12N9/00
Filed: 2000-02-03
Abstract: The present invention provides a process for producing a purine nucleotide which comprises: culturing in a medium a microorganism having the ability to produce a precursor of the purine nucleotide and carrying an introduced DNA which can induce and express an enzyme capable of synthesizing the purine nucleotide from said precursor; allowing said precursor of the purine nucleotide to accumulate in the culture; inducing and expressing the enzyme capable of synthesizing the purine nucleotide from said precursor; allowing the purine nucleotide formed from said precursor to accumulate in said culture; and then recovering said purine nucleotide therefrom. Microorganisms useful in said process are also provided.
Patent MX-PA00008996-A (MX)
Title: Pre-filled retractable needle injection device.
Inventor: BOTICH MICHAEL J
IPC: A61M5/24
Filed: 1999-03-01
Abstract: A needle-bearing device (10) for injecting medicinal fluid from a pre-filled vial is provided. After use, the needle (50) is retracted into the body of the device to prevent inadvertent contact with the sharpened end of the needle (50). In one embodiment, the invention provides a manually actuable button that effectuates retraction of the needle (50) after use. In another embodiment, retraction is effectuated automatically after the injection is complete.
Patent MX-PA01004132-A (MX)
Title: Ambient atmospheric pressure compensation controller for pressurized copying device.
Inventor: KARL KHALED B AYASH
IPC: H05K5/02
Filed: 2001-04-25
Abstract: A method and apparatus for maintaining the air pressure within a xerographic module (1) of an image forming device above the ambient pressure outside of the xerographic module (1). A pressure sensor, (e.g., an altimeter) is used to monitor ambient atmospheric pressure, and a controller maintains the air pressure at a determined set point or within a determined range so that the risk of contaminants entering the xerographic module (1) and adversely affecting its internal elements is reduced.
Patent MX-PA01006950-A (MX)
Title: Biochemically enhanced thermophilic treatment process.
Inventor: ENOS L STOVER
IPC: C02F3/00
Filed: 1999-11-08
Abstract: The present invention provides a process and apparatus for autothermal aerobic thermophilic treatment of high strength and high temperature wastes. Waste material is injected into a reactor vessel (12) having thermophilic microorganisms to form a volume of bulk liquid in the reactor vessel (12). An oxygencontaining gas is also injected into the reactor vessel (12) for aerobic treatment of the waste material. The oxidationreduction potential and temperature of the reactor bulk liquid are monitored and at least a selected one of the rate of injection of the oxygencontaining gas, the oxygentransfer efficiency of the oxygencontaining gas and the volume of bulk liquid in the reactor (12) are adjusted in response to the oxidationreduction potential and temperature of the reactor bulk liquid to maintain the temperature of the reactor bulk liquid within a predetermined range.
Patent MX-PA01007151-A (MX)
Title: Improvements in and relating to processing materials.
Inventor: GREGSON PAUL RAYMOND
IPC: G21C19/48
Filed: 2000-01-14
Abstract: The invention provides a series of techniques for processing uranium containing feed materials such as uranium ores, reprocessed uranium, uranium containing residues and uranium containing spent fuel. The processes described involve fluorination of uranium containing material, separation of the uranium containing material from other materials based on ionisation thereof with the non-ionised fluorine containing material being recycled. Metallic uranium and/or plutonium and/or fission products may result. The technique offers advantages in terms of the range of materials which can be reprocessed and a reduction in the number of complexity of stages which are involved in the process.
Patent MX-PA01011401-A (MX)
Title: Fap-activated anti-tumor compounds.
Inventor: FIRESTONE RAYMOND ARMAND
IPC: A61K47/48
Filed: 2000-05-11
Abstract: The invention relates to a prodrug that is capable of being converted into a drug by the catalytic action of human fibroblast activation protein (FAPalpha), said prodrug having a cleavage site which is recognised by FAPalpha, and said drug being cytotoxic or cytostatic under physiological conditions.
Patent MX-PA01012359-A (MX)
Title: Fluid mixing apparatus.
Inventor: SCHILLER STEVEN E
IPC: B01F15/02
Filed: 2000-06-01
Abstract: A reduced pressure shut off assembly for an eductor (36) mixing system wherein a vacuum shut off valve (20) is activated by reduced pressure in a reduced pressure line (51, 57) connected to a container (21) for a concentrate. In a preferred embodiment, an eductor and the vacuum shut off valve are positioned on top a vessel for storing a solution of the concentrate. The mixing system with the vacuum shut off valve is especially adapted to be used for mixing a chemical concentrate cleaning composition with water.
Patent MX-PA02003735-A (MX)
Title: Media system and remote controller for controlling the media system.
Inventor: YOUNG JEFFREY J
IPC: H04B1/20
Filed: 2000-06-14
Abstract: A media system capable of sending a plurality of input signals to a receiving device of the system is provided. A remote control for selecting among the input devices is also provided. An audio remote without numeric keys for an audio system is disclosed. The present invention also provides the user with the ability to control the output of an input selection key. This allows the user to select input source, perhaps from a table, or execute a function assigned to the key. When in a locked state, the input key will rotate through a table that contains individual input functions from target devices, or the target sources devices. The table may consist of as many input functions are as available for each device. In an unlocked state the remote will attempt to send a function assigned to the input key prior to selecting a device selection from an input select table. Other features of a remote control for a media system are disclosed.
Patent MX-PA02010141-A (MX)
Title: Luminary device with thermochromatic label.
Inventor: CARPENTER SCOTT M
IPC: B44C1/10
Filed: 2001-03-30
Abstract: A decorated luminary product (1) includes either a candle (25) or a candle holder (20) containing the candle. A decorative web (10) of a heat shrinkable polymer web is heat shrunk to conform to a shape of the one of the candle and the candle holder. The web is decorated with a thermochromic ink or pigmentation (12) to cooperate with heat emitted by burning the candle to provide a visible change in the ink or pigmentation, so as to provide a pleasing visual effect when the candle is burned.
Patent MX-PA02010438-A (MX)
Title: Inhibitors of dipeptidyl peptidase iv.
Inventor: PITT GARY ROBERT WILLIAM
IPC: A61P3/10
Filed: 2001-04-26
Abstract: Compounds according to general formula (1), wherein R1 is H or CN, X1 is S, O, SO2 or CH2, X2 is O, S or CH2, X3 is NR5 or a carbonyl or thiocarbonyl group and R4 is R6R7N, R8(CH2)qOC(=O), R8(CH2)qOC(=S), R6R7NC(=O), R6R7NC(=S); R8(CH2)qC(=O), R8(CH2)qC(=S) or R8(CH2)qSO2, m is 1 3 and n is 0 4 are new. The compounds of the invention are inhibitors of dipeptidyl peptidase IV. Pharmaceutical compositions of the compounds of the invention, or pharmaceutically acceptable salts thereof, are useful in the treatment of,inter alia, type 2 diabetes.
Patent MX-PA02010672-A (MX)
Title: Method and apparatus for managing credit inquiries within account receivables.
Inventor: LAND DAVID
IPC: G06Q40/00
Filed: 2001-04-30
Abstract: In one embodiment of the invention, the ARS's Credit Inquiry Module reviews payment history and performs credit inquiries. Credit Inquiry is the ability to go into a customer account and view a very rich and diverse supply of data used for customer analysis, credit management, and customer contact. The Credit Inquiry Module based on customer payment data predicts overall cash forecasting for the client. The Credit Inquiry Module is utilized for account reconciliation and audit verification for tracking transactions at the customer level.
Patent MX-PA02011001-A (MX)
Title: Domestic refrigerator with improved thermal insulation.
Inventor: GAMBERONI LUCA
IPC: F25D23/06
Filed: 2002-11-08
Abstract: A domestic refrigerator or freezer comprises a food storage compartment delimited by insulated walls (10) and by one or more access doors to said compartment, in which one or more walls (10) and/or doors are provided with a metallic film (12), preferably a metallised polymeric film, capable of enhancing the performance of the refrigerator with regard to energy saving.
Patent MX-PA03000924-A (MX)
Title: Time-based selection of epg data destined for low resource clients.
Inventor: BARRETT PETER T
IPC: H04N7/16
Filed: 2003-01-30
Abstract: Program data for use in electronic program guides is selected for storage at a low resource client according to a preference for current program data over program data for a future time. In the described implementation, a memory representative of the client memory is disproportionately allocated for different time units (e.g., 24-hour days) to be represented in an electronic program guide. Analysis is conducted as to whether program data for the different time units can fit in the portions of memory and adjustments to the amount of program data for respective time units are made. Different-size sets of program data are eventually selected such that more program data will be stored in the portion of memory corresponding to the current time unit and progressively less program data will be stored in other portions of memory corresponding to future time units.
Patent MX-PA03003747-A (MX)
Title: Agrochemical composition.
Inventor: HAESSLIN HANS WALTER
IPC: A01N25/32
Filed: 2001-10-29
Abstract: Agrochemical composition in the form of a suspension concentrate, comprising, in addition to other customary formulation auxiliaries, a surfactant compound and a quinoline protection agent of Formula I (see formula) wherein n is 2 a
Patent MX-PA03005866-A (MX)
Title: Matrix metalloproteinase inhibitors.
Inventor: STEPHEN QUIRK
IPC: C07C235/84
Filed: 2001-12-21
Abstract: The present invention provides compounds that are effective in treating disorders caused by the enzymatic activity of matrix metalloproteinases. These disorders include, but are not limited to, rheumatoid arthritis, osteoarthritis, periodontal disease, aberrant angiogenesis, tumor invasion and metastasis, corneal ulceration, and in complications of diabetes. The present invention is also is useful for treating wounds.
Patent MX-PA03007458-A (MX)
Title: Adjustable mold for forming shaped foods.
Inventor: GROOTE JAN-HENDRIK DE
IPC: A21B3/13
Filed: 2003-08-20
Abstract: A food mold including one or more molding pockets (18), at least one of which includes a primary molding chamber (24) and a secondary molding chamber (26) pivotally or flexibly joined to the primary chamber (24) for selective positioning of the secondary chamber (26) in communication and alignment with the primary chamber (24) to define a first mold configuration, and a second position wherein the secondary chamber (26) is inverted into the primary chamber (24) to define a second mold configuration substantially smaller than the first mold configuration.
Patent MX-PA03011040-A (MX)
Title: Herbicidal composition.
Inventor: WILLY T R EGG
IPC: A01N43/70
Filed: 2002-06-12
Abstract: Selectively herbicidal composition for controlling grasses and weeds in crops of useful plants comprising a) a herbicidally effective amount of a compound of formula (I), and b) an amount, effective for herbicide antagonism, of the compound of formula (II), wherein the substituents have the meanings given in claim 1.
Patent MX-PA04004789-A (MX)
Title: Hybrid parallel/serial bus interface.
Inventor: TIMOTHY A AXNESS
IPC: H04L29/00
Filed: 2002-11-19
Abstract: A hybrid serial/parallel bus interface has a data block demultiplexing device (40). The data block demultiplexing device (40) has an input configured to receive a data block and demultiplexes the data block into a plurality of nibbles (42(2)). For each nibble, a parallel to serial converter (42i) converts the nibble into serial data. A line transfers each nibble's serial data. A serial to parallel converter (46i) converts each nibble's serial data to recover that nibble. A data block reconstruction device (48) combines the recovered nibbles into the data block.