baber/WOPTO huggingface dataset:
Patent DK-0909164-T3 (DK)
Inventor: MOLLEE HINDERIKUS MARIUS
IPC: A61K9/127
Filed: 1997-05-12
Granted: 2002-12-16
Abstract: A powder of reversed vesicles, which comprises one or more non-ionic surfactants and optionally a lipophilic stabilising factor and a bio-active agent, is provided. The product is prepared by making a dispersion of reversed vesicles in a suitable apolar vehicle, which vehicle is subsequently removed. In admixture with one or more excipients the product can be incorporated in compositions.
Patent DK-0920505-T3 (DK)
Inventor: GORMAN DANIEL M
IPC: A61K48/00
Filed: 1997-08-14
Granted: 2008-09-08
Abstract: Purified genes encoding a T cell surface antigen from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding this antigen are provided. Methods of using said reagents and diagnostic kits are also provided.
Patent DK-1017403-T3 (DK)
Inventor: SZPORNY LAIZLO
IPC: A61K47/48
Filed: 1998-04-28
Granted: 2006-07-31
Abstract: The invention relates to pharmaceutical compositions against peptic ulcer as well as to a method of treating peptic ulcer. The compositions contain and the method of treatment employs zinc hyaluronate as an active ingredient having a molecular weight in the range of 500,000 to 1,200,000 daltons.
Patent DK-0942000-T3 (DK)
Inventor: BUHR CHRIS A
IPC: C12N15/09
Filed: 1990-10-24
Granted: 2004-11-01
Abstract: Oligomers which have substituents on the 2' position are resistant to oligonucleases and furthermore can be derivatized to deliver reagents or drugs, to carry label, or to provide other properties.
Patent DK-1038881-T3 (DK)
Inventor: ROEMISCH JUERGEN DR
IPC: C07K1/22
Filed: 1999-12-07
Granted: 2007-01-08
Abstract: A process for the partial or complete separation of glycosylated and nonglycosylated proteins is described, in which: a) a triazine dye immobilized on a matrix is incubated with a mixture of glycosylated and nonglycosylated proteins, b) the matrix is then washed to remove the unbound proteins, and c) the proteins are eluted by means of a stepwise or continuous increase in the ionic strength or in the pH, nonglycosylated proteins and proteins having an increasing degree of glycosylation being collected separately from one another in the eluate fractions obtained. By means of the use of this process it is possible, for example, to prepare a human albumin which is free of glycoside bonds and is expressed in yeast cells.
Patent DK-0933111-T3 (DK)
Inventor: BERGMANN EUGEN O
IPC: B01D29/62
Filed: 1999-01-28
Granted: 2008-06-30
Abstract: A concurrent backwash distribution apparatus for a filter (11) having a filter tank (13) and a plurality of underdrain laterals (24) includes a baffle (10) positioned in a common main conduit (12) to define an auxiliary flume (14) between the baffle (10) and the underdrain laterals (24). The auxiliary flume (14) is in fluid communication with the common main conduit (12) and the underdrain laterals (24). The baffle (10) has at least one flume liquid metering orifice (16) preferably located near the bottom of the baffle (10) so that it may be below a gas/liquid interface in the auxiliary flume (14) during concurrent gas/liquid backwash operations. A flow distribution plate (18) may be positioned between the auxiliary flume (14) and the underdrain laterals (24), the flow distribution plate (18) having at least one liquid metering orifice and at least one gas metering orifice. The baffle (10) may take one of many forms. The baffle (10) creates an adequate liquid pool in the common main conduit for low velocity flow of backwash liquid while at the same time providing uninhibited flow of backwash gas. Maldistribution is thereby controlled. Stand-pipes (35) may be used in place of the baffle (10). A method for concurrent gas/liquid backwash according to the invention is also disclosed. The invention may be applied to flat bottom flumes or insufficiently recessed flumes. <IMAGE>
Patent DK-1051464-T3 (DK)
Inventor: MAGNIN CESAR
IPC: C10L1/32
Filed: 1999-12-08
Granted: 2004-11-01
Abstract: A process and apparatus for industrial-scale preparation of an emulsified fuel including a water phase in a continuous organic phase which contains less than 20% by volume of water, and at least one additive necessary for forming the emulsified fuel. The fuel is formed by mixing and homogenizing the organic phase and the additives, forming a volume V, inside an homogenization tank with internal circulation rate Qc, such that Qc/V>=100 h-1, circulating the homogenized fluid in a branch loop emerging from the tank at a rate Qcirc, and through at least one emulsifying system located on said loop, at a rate such that 0 h<V/Qcirc<=2 h, feeding the aqueous phase into the branch loop upstream of the emulsifying system, and maintaining the homogenization in the tank and the circulation of the liquid in the branch loop until the emulsion acquires a desired characteristic of storage stability.
Patent DK-1143955-T3 (DK)
Inventor: ERION MARK D
IPC: A61P3/08
Filed: 1999-12-22
Granted: 2005-11-14
Abstract: Pharmaceutical compositions containing an FBPase inhibitor and an insulin sensitizer are provided as well as methods for treating diabetes and diseases responding to increased glycemic control, an improvement in insulin sensitivity, a reduction in insulin levels, or an enhancement of insulin secretion.
Patent ES-2216764-T3 (ES)
Inventor: HOBISCH GERALD DR
IPC: C09D175/04
Filed: 2000-06-14
Granted: 2004-11-01
Abstract: A water dilutable, urethane modified paste- and mixing resin comprises an aldehyde or ketone resin, a multifunctional isocyanate having at least 2 isocyanate groups per molecule on average, an aliphatic acid and an aliphatic polyether. A water dilutable, urethane modified paste- and mixing resin (I) (A) 10-90 % of an aldehyde or ketone resin having a hydroxyl number of 20-300 mg/g, a softening point of 60-140 degrees C and a number average mol. wt. of 500-3000 g/mol. (B) 5-30 % of a multifunctional isocyanate having at least 2 isocyanate groups per molecule on average (C) 0-30% of an aliphatic acid having at least one acid group and at least one group that can react with an isocyanate to form a urethane or urea (D) 0-70 % of an aliphatic polyether having an average mol. wt. (Mn) of 200-8000 g/mol and at least one hydroxyl group per molecule. (I) contains at least one of (C) or (D) and is optionally neutralized with aqueous ammonia or an amine, when (I) contains (C). An Independent claim is included for a process for the preparation of (I) by mixing components (A)-(D) at 30-200 degrees C until the isocyanate group content is less than 0.1%, followed by the addition of a water dilutable solvent (E) in a wt. ratio of (E) to ((A)-(D)) is 1:9-9:1 and optionally neutralization.
Patent ES-2211454-T3 (ES)
Inventor: JOE DAISY
IPC: C07D209/52
Filed: 2000-09-18
Granted: 2004-07-16
Abstract: This invention relates to compounds of Formula I <CHEM> or stereoisomers, pharmaceutically acceptable salts or prodrugs thereof or a pharmaceutically acceptable salts of the prodrugs. This invention also relates to pharmaceutical compositions comprising a compound of Formula I, and to methods of treatment of diabetes, insulin resistance, diabetic neuropathy, diabetic nephropathy, diabetic retinopathy, cataracts, hyperglycemia, hypercholesterolemia, hypertension, hyperinsulinemia, hyperlipidemia, atherosclerosis, or tissue ischemia.
Patent ES-2213568-T3 (ES)
Inventor: HELLER MLADEN
IPC: E05D7/00
Filed: 2000-02-01
Granted: 2004-09-01
Abstract: A hinge plate for doors, windows and the like comprising a hinge-plate frame section consisting of a hinge section and a mounting part (11), in addition to a wing hinge-plate (20) consisting of a hinge section (22) and a mounting part. The hinge section (22) of the wing hinge-plate (20) overlaps with the hinge section of the hinge-plate frame section and the hinge sections (22) in the overlap area are pivotally connected to each other by means of a bolt (5) that is engaged in recesses (13) of the hinge sections (22) and forms the hinge pin (S). The length of the recess (13) of one of the hinge sections is greater than the width thereof, whereby the bolt (5) is provided with an amount of play along the longitudinal center line (17) of the cross section of the  recess and can be displaced in a parallel manner along an adjustment path (18). A strip-shaped filler arrangement (30) that can be displaced parallel to the bolt (5) and is placed between at least one end of the recess (13)  and the bolt (5) in the region of the longitudinal center line (17) reduces the amount of play for said bolt (5) along the longitudinal center line (17) and fixes the bolt (5) in a specific position. The filler arrangement (30) comprises at least one element (32, 33) that at least partially fills the open gap that remains between the bolt and the end wall.
Patent ES-2316352-T3 (ES)
Inventor: OKUNO KAZUAKI
IPC: C12P21/02
Filed: 2000-03-03
Granted: 2009-04-16
Abstract: By clarifying the properties of OmpT protease, a novel use thereof as a protease and a novel method of producing a target polypeptide are provided. More particularly, the present invention relates to a method of controlling cleavage of a polypeptide by OmpT protease which comprises converting a sequence site consisting of two arbitrary consecutive amino acids and/or amino acid(s) in the vicinity of said site in said polypeptide into other amino acids, characterized by (1) setting lysine or arginine as the amino acid at the -1-position concerning said site and setting a specific amino acid as the amino acid at the +1-position; and/or (2) setting specific amino acid(s) as the amino acid(s) at the -4-position and/or the -6-position relative to said site; so that desired parts of said polypeptide are cleaved by OmpT protease and/or undesired parts of said polypeptide are not cleaved by ompT protease. For example, the present invention provides a method of treating by OmpT protease a fusion protein having an amino acid sequence wherein the amino acid at the +1-position is X (wherein X is an amino acid other than glutamic acid, aspartic acid or proline); and a method of controlling cleavage by converting the amino acids at the -6-position and the -4-position concerning the cleavage site into amino acids other than acidic amino acids.
Patent ES-2246837-T3 (ES)
Title: Escobilla para herramienta mecanica.
Inventor: UEDA YASUHISA
IPC: B23Q11/08
Filed: 2000-04-04
Granted: 2006-03-01
Abstract: Una escobilla para una(s) herramienta(s) mecánica(s) que comprende: una porción de conexión (3) a unir a la herramienta mecánica, en la que la herramienta mecánica se mueve en relación a una superficie de deslizamiento (14); y un cuerpo de escobilla (10) hecho de un material elástico integrado con la porción de conexión (3), en donde una porción labial (11) del cuerpo de escobilla (10) puede deslizar sobre la superficie de deslizamiento (14); caracterizada porque la porción labial (11) del cuerpo de escobilla (10) está recubierta con un material tejido (5) y el material tejido (5) se provee sobre al menos un lado de la superficie de deslizamiento de la porción labial (11) del cuerpo de escobilla (10), en donde el material tejido (5) está hecho de tejido con ligamiento, y siendo los hilos de trama (5a) del tejido con ligamiento ortogonales a una dirección de deslizamiento de la porción labial (11), estando la finura de los hilos de trama (5a) en el intervalo de 80 a 500 deniers, estando la finura de los hilos de urdimbre (5b)en el intervalo de 40 a 250 deniers, y siendo la finura de los hilos de urdimbre (5b) menor que la de los hilos de trama (5a).
Patent ES-2338747-T3 (ES)
Inventor: BIJLSMA PIETER BRANDT
IPC: A23L33/00
Filed: 2000-03-21
Granted: 2010-05-12
Abstract: A nutritional composition which contains slightly negatively charged non-digestible polysaccharides having a molecular weight of 8 kD to 40,000 kD, characterized in that the rise in the viscosity of the composition caused by the polysaccharides is less than 20 mpa.s. This nutritional composition is used to reduce the uptake of high molecular weight substances, allergens and microorganisms through the intestinal wall, more particularly to reduce transport of high molecular weight substances, allergens and microorganisms through the intestinal wall, ore particularly to reduce transport of high molecular weight substances, allergens and microorganisms through the tight junctions in the intestines. The nutritional compositions can be used to prevent or to treat allergies, allergic reactions, sepsis and inflammatory processes, such as those which can arise under emotional and physical stress, ischaemia, reperfusion damage during and after operations, following radiation treatment and/or chemotherapy of cancer patients and in the case of inflammatory intestinal diseases, diarrhoea and allergies.
Patent ES-2195883-T3 (ES)
Inventor: LAYNE RICHARD
IPC: A61F2/04
Filed: 2000-02-02
Granted: 2003-12-16
Abstract: A method of making an implantable medical device includes extruding a first ePTFE tube and a second ePTFE tube, cutting a plurality of slits in the first ePTFE tube, positioning a radially expandable support layer between the first and second ePTFE tubes so that the slits span portions of the support layer, and laminating the first ePTFE tube to the second ePTFE tube through openings in the support layer.
Patent ES-2233354-T3 (ES)
Inventor: UHLIANUK PETER WILLIAM
IPC: C08G18/42
Filed: 2000-03-16
Granted: 2005-06-16
Abstract: The present invention provides for an etch and mar resistant low VOC clear coating composition most suitable for use as a top clear coat in multi-layered OEM or refinish automative coatings. The coating composition includes isocyanate, silane and melamine components. The isocyanate component includes an aliphatic polyisocyanate. The composition may be formulated as a two-pack or one-pack coating composition, wherein the isocyanante functionalities are blocked with a blocker such as a mono-alcohol.
Patent ES-2231175-T3 (ES)
Inventor: SERBAN BOGDAN
IPC: B60R21/01
Filed: 2000-02-28
Granted: 2005-05-16
Abstract: A system for stopping the deployment of an airbag in a vehicle includes a detector for detecting a position of the airbag with respect to an occupant of the vehicle and an airbag operating device. The detector is located on the airbag in an area which, upon deployment of the airbag, is facing the occupant of the vehicle. The detector generates a position signal which is sent to the airbag operating device such that the airbag operating device stops the deployment of the airbag when the position signal indicates a predetermined position of the airbag in relation to the occupant.
Patent ES-2206270-T3 (ES)
Title: Material para lentes de contacto.
Inventor: KUNZLER JAY F
IPC: C08G77/06
Filed: 2000-06-20
Granted: 2004-05-16
Abstract: Un método de formación de un hidrogel de silicona que comprende la polimerización de una mezcla de monómeros consistente en prepolímeros de silicona que tienen la fórmula general: **FORMULA** donde: A es un radical insaturado activado que incluye al menos un sustituyente que facilita la polimerización por radicales libres; A¿ es un radical insaturado activado que incluye al menos un sustituyente que facilita la polimerización por radicales libres o un grupo alquilo; R1-R10 son independientemente un grupo alquilo, fluoroalquilo, alcohol, éter o fluoroéter que tiene 1-10 carbonos, o un grupo aromático que tiene 6-18 carbonos; m, n y p son independientemente 0 a 200, siendo m+n+p de aproximadamente 15 a 200; a es 1 a 10, y b es 0 a 10, donde el prepolímero de silicona es preparado por reacción de un siloxano cíclico (D) y un dimetacrilato disiloxano (M2) en presencia de un catalizador, y se añade al menos un disiloxano (T2) de fórmula: **FORMULA** donde R11-R16 son independientemente un grupoalquilo que tiene 1 a 5 carbonos, a la mezcla de reacción utilizada para formar el prepolímero de silicona.
Patent ES-2308989-T3 (ES)
Inventor: CARTER BARRIE
IPC: C12N1/21
Filed: 2000-08-08
Granted: 2008-12-16
Abstract: The present invention provides a recombinant adeno-associated virus (rAAV) virus preparation, which rAAV virus preparation is essentially free of other viruses, comprising an rAAV vector, wherein the rAAV vector comprises a single-stranded heterologous nucleotide sequence comprising a coding region which forms intrastrand base pairs such that expression of the coding region of the heterologous sequence is enhanced relative to an rAAV vector that lacks sufficient intrastrand base pairing to enhance said expression, wherein the rAAV vector comprises one or more inverted terminal repeat (ITR) sequences flanking said heterologous sequence, wherein the rAAV vector is less than 2.5 kilobases in length, wherein the total amount of unique sequence present in the heterologous sequence is about one-half of the heterologous sequence and wherein the heterologous sequence forms intrastrand base pairs along most or all of its length, for use in a method of treatment of the human or animal body by therapy.
Patent ES-2303512-T3 (ES)
Inventor: GAHLER ROLAND J
IPC: A61K31/715
Filed: 2000-08-11
Granted: 2008-08-16
Abstract: In one aspect, the present invention provides Echinacea compositions including standardized amounts of at least two Echinacea components. More preferably the Echinacea compositions of the present invention include standardized amounts of at least three Echinacea components. Presently preferred Echinacea components are cichoric acid, Echinacea alkylamides and Echinacea polysaccharides. In another aspect, the present invention provides methods for preparing Echinacea compositions, the methods including the step of combining amounts of at least two Echinacea components, preferably three Echinacea components, sufficient to yield an Echinacea composition including standardized amounts of each of the combined Echinacea components. In yet another aspect, the present invention provides Echinacea extracts, and methods for preparing Echinacea extracts. Presently preferred Echinacea extracts are enriched in one or more members of the group consisting of polysaccharides, alkylamides and cichoric acid. In yet another aspect, the present invention provides methods for enhancing immune system activity in a mammal.
Patent ES-2316385-T3 (ES)
Inventor: KARMI GADI
IPC: G06F9/50
Filed: 2000-09-27
Granted: 2009-04-16
Abstract: In a system including a resource (100) which is shared among a number of users, it is difficult to distribute the available capacity of the resources fairly among the users and still maximize resource utilization. Additionally, it is desirable to allow at least some of the control over usage rates to remain with the users, while at the same time avoiding situations where the resource is overloaded. A system and method are disclosed wherein usage rates are selected from among a set of available rates according to a set of persistence vectors.
Patent ES-2270877-T3 (ES)
Title: Sistema de limpieza utilizando un solvente de lavado organico y un solvente fluido presurizado.
Inventor: RACETTE TIMOTHY L
IPC: B08B3/08
Filed: 2000-10-13
Granted: 2007-04-16
Abstract: Un proceso para lavado de substratos que consta de los siguientes pasos: Colocación de los substratos a lavar en un tambor (212), donde el tambor (212) está ubicado dentro de un recipiente (210) que tiene por lo menos una pared; adición de solvente orgánico al recipiente (210) y/o al tambor de lavado (212) donde el recipiente (210) no es presurizado y el solvente orgánico está en un estado líquido a, o substancialmente cerca a, condiciones de no presurización; Lavado de los substratos; remoción de una porción del solvente orgánico del recipiente (210); presurización del recipiente (210) y adición de solvente fluido presurizado al recipiente (210); remoción de una porción del solvente fluido presurizado del recipiente (210); y remoción de los substratos del recipiente (210). caracterizado por que El tambor (212) es perforado y giratorio y los substratos son lavados por agitación y/o rotación del tambor (212).
Patent ES-2204716-T3 (ES)
Title: Forma de impresion para maquina rotativa de serigrafia fabricada a partir de material plastico reforzado con fibras.
Inventor: VAN WEPEREN KARST JAN
IPC: C08J5/04
Filed: 2000-10-17
Granted: 2004-05-01
Abstract: Forma de impresión (10) para máquina rotativa de serigrafía, que comprende un cilindro hueco de pared delgada (12) fabricado a partir de material plástico reforzado con fibra, cuya pared está provista de orificios de impresión continua (14) que definen una imagen (16, 18) que se ha de imprimir, caracterizada por el hecho de que el cilindro (12) comprende por lo menos una capa (20; 32, 34; 32, 44, 46) que tiene fibras (22) con al menos una dirección orientada de las fibras.
Patent ES-2259294-T3 (ES)
Inventor: EKLOF AKE
IPC: E21B6/02
Filed: 2000-10-13
Granted: 2006-10-01
Abstract: A method and device for controlling a rock drilling machine (51) includes an impact device (5) arranged to act on a drilling tool (52), a rotation motor (7) for rotating the drilling tool (52), and a feed motor (6) for feeding the drilling tool (52) against a ground surface (53). The pressure to an inlet (30) of the rotation motor (7) is sensed, and the pressure to an inlet (32) of the feed motor (6) is reduced, for the purpose of maintaining the pressure to the rotation motor substantially constant, when the pressure to the inlet (30) of the rotation motor (7) exceeds a first predetermined value (41). When the pressure to the inlet (30) of the rotation motor (7) exceeds a second predetermined value (42), the pressure to an inlet (31) of the impact device (5) is controlled to be inversely proportional to the pressure to the inlet (30) of the rotation motor (7).
Patent ES-2244544-T3 (ES)
Inventor: RUDEL WERNER
IPC: F16B21/02
Filed: 2001-12-19
Granted: 2005-12-16
Abstract: Device for holding an article on an object, especially a wall, comprises a fixing rod (1) for holding the article on one end, and a fixing element (2) for fixing the fixing rod in a bore in the object and having an elongated element body with an axial hollow chamber for receiving the fixing rod. The element body is expanded in the radial direction to clamp the fixing element in the bore. The fixing rod has in at least one section a cross-section which is wider in a first radial direction than in a second radial direction so that expansion of the element body can occur with less than one full rotation of the fixing rod. <??>Independent claims are also included for the above fixing rod, for the above fixing element, and for a process for the fixing of the above device. Preferred Features: A covering cap slides onto the fixing rod to seal off the bore from dirt.
Patent ES-2274855-T3 (ES)
Inventor: SELVITELLI DAVID M
IPC: A61B17/58
Filed: 2001-08-08
Granted: 2007-06-01
Abstract: An orthopaedic method and anchor assemblies for anchoring a linkage such as a rod or cable used for fixation or reduction. One assembly includes an anchor plate (102a,102b) and a slotted anchor bolt (12) that captures the plate in a one-piece assembly for convenient installation. The base of the anchor bolt lies below the plate, and a cap or nut tightens down to secure a linking member, e.g., a rod or cable, in the slot, simultaneously clamping the bolt to fix both its position and its orientation on the plate. One occipital plate has lateral arms (112,114) that hold the anchor bolts, and a Y-shaped embodiment is mounted in an inverted orientation to position the anchor bolts well down in soft tissue for more effective wound closure. A cable connector (200) is used together with an anchor plate, vertebra anchor screws and fixation rods to secure ends of a cable at the level of one or more vertebrae, providing a versatile and highly stable system for alignment, fixation and fusing of the cervical and thoracic spine. The cable connectors have an open-sided channel that fits onto and securely clamps to an already-positioned fixation rod, with an eyelet or other structure providing a rigid and fixed securing point for a cable that is threaded about the vertebrae under tension. Methods of fixation are described.