baber/WOPTO huggingface dataset:
Patent AU-2022201319-A1 (AU)
Title: Viral vectors encoding recombinant fviii variants with increased expression for gene therapy of hemophilia a
Inventor: Falkner Falko-Günter
IPC: C12N15/86
Filed: 2022-02-25
Abstract: The present disclosure provides a polynucleotide including a nucleotide sequence encoding a Factor VIII 
polypeptide. The Factor VIII polypeptide includes a light chain, a heavy chain, and a polypeptide linker 
joining the C-terminus of the heavy chain to the N-terminus of the light chain. The heavy chain of the Factor 
VIII polypeptide is encoded by a first nucleotide sequence having at least 95% identity to CS4-HC-NA (SEQ 
ID NO: 3). The light chain of the Factor FVIII polypeptide is encoded by a second nucleotide sequence having 
at least 95% identity to CSO4-LC-NA (SEQ ID NO: 4). The polypeptide linker comprises a furin cleavage site.  
The disclosure also provides mammalian gene therapy vectors and methods for treating hemophilia A.
Patent AU-2022202009-A1 (AU)
Title: Pyrazolopyridine derivatives as hpk1 modulators and uses thereof for the treatment of cancer
Inventor: Ye hai-fen
IPC: A61K31/437
Filed: 2022-03-23
Abstract: Disclosed are compounds of Formula (I), methods of using the compounds for 
inhibiting HPK1 activity and pharmaceutical compositions comprising such compounds.  
The compounds are useful in treating, preventing or ameliorating diseases or disorders 
associated with HPK1 activity such as cancer.
Patent AU-2022202411-A1 (AU)
Title: Non-dairy formulae
Inventor: KESLER URIEL
IPC: A23L33/15
Filed: 2022-04-12
Abstract: The present invention is directed to non-dairy almond based formulae for the 
preparation of infant or toddler formula or other types of supplemental or functional 
food.  
02266760\2-01
Patent AU-2022205222-A1 (AU)
Title: Pyrazolopyridine Derivative Having GLP-1 Receptor Agonist Effect
Inventor: YOSHINO HITOSHI
IPC: A61K31/496
Filed: 2022-07-13
Abstract: The present invention provides a compound represented by formula (I) in which an indole ring or a 
pyrrolo[2,3-b]pyridine ring and a pyrazolopyridine skeleton are bonded using a substituent, or a salt 
of the compound; solvates thereof; and prophylactic or therapeutic agents for non-insulin-dependent 
diabetes mellitus (type 2 diabetes mellitus), obesity, and the like in which said compound, salt, or 
solvate is used as an active ingredient. (In the formula, X, Y, Q', Q2 , R', R2 , R3, R4, R5 , R6 , R7, R8 , R9, 
nl, n2, Z', and Z2 represent substances indicated in the present specification.)
Patent AU-2022209478-A1 (AU)
Title: Lifting apparatus and method for hoisting a gyratory crusher spider
Inventor: MULLER CHRIS
IPC: B66C1/10
Filed: 2022-01-25
Abstract: A lifting apparatus (100) for hoisting a spider (200) of a gyratory crusher has a spreader (110) spanning between two leg members (120) each having an offset arm (121a), clearing arm (121 b), cradle arm (121c), and securing arm (121 d). The offset arm (121a) forms a second offset distance (131) with respect to an offset axis (C). The arms (121 a-121 d) form an opening (123) for receiving the spider (200). The leg members (120) oppose each other such that the clearing arms (121 b) of the leg members (120) are provided on opposite sides of a plane defined by the horizontal axis (D) and vertical axis (A). The lifting apparatus (100) may be lowered over the spider (200), and rotated approximately 90 degrees in a direction (B) of rotation about the vertical axis (A) to cradle and support the spider (200) from below the spider (200).
Patent AU-2022235597-A1 (AU)
Title: System of medical indicators having multisensory, multipurpose and multifunctional features
Inventor: FRIEDMAN DAVID J
IPC: A61B90/90
Filed: 2022-09-22
Abstract: The exemplary embodiments provide a mechanism for the rapid and repeated identification of the 
correct IV line to use in an emergency situation. The exemplary embodiments further provide the 
application of a specific label on the line to denote the medication in use. In an embodiment, an 
indicator includes a body having a first end, a second end opposite the first end, a first surface and a 
second surface opposite the first surface, each of which extends from the first end to the second 
end, and an aperture extending from the first end to the second end, the aperture being sized and 
shaped to receive a tube, and at least one of the first and second surfaces including a haptic 
signature formed thereon.
WO 2020/046535 PCT/US2019/044711 
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'I 
00
Patent AU-2022241555-A1 (AU)
Title: Pitch Filter for Audio Signals and Method for Filtering an Audio Signal with a Pitch Filter
Inventor: RESCH BARBARA
IPC: G10L19/02
Filed: 2022-09-29
Abstract: In some embodiments, a pitch filter for filtering a preliminary audio signal 
generated from an audio bitstream is disclosed. The pitch filter has an 
5 operating mode selected from one of either: (i) an active mode where the 
preliminary audio signal is filtered using filtering information to obtain a filtered 
audio signal, and (ii) an inactive mode where the pitch filter is disabled. The 
preliminary audio signal is generated in an audio decoder having a coding 
mode selected from one of at least two distinct coding modes, and the pitch 
10 filter is capable of being selectively operated in either the active mode or the 
inactive mode based on control information while the audio decoder is 
operating in the coding mode. A method for filtering a preliminary audio signal 
with a pitch filter substantially as described above is also disclosed.
Patent AU-2022250077-A1 (AU)
Title: Single vessel multi-zone bioreactor for simultaneous culture of multiple microbial strains
Inventor: METTU SRINIVAS
IPC: C12M1/00
Filed: 2022-03-30
Abstract: A single vessel multi-zone bioreactor for simultaneously culturing multiple microbial strains comprising multiple culturing zones arranged sequentially, each culturing zone comprising a porous hydrogel, and the use thereof for producing optionally encapsulated probiotics.
Patent AU-2022267009-A1 (AU)
Title: Methods and devices for hearing training
Inventor: PHILPOTT AMANDA
IPC: A61B5/12
Filed: 2022-04-27
Abstract: A computer implemented method, user device and non-transitory computer-readable medium storing instructions for performing hearing training with a user device comprising a user interface and an audio output, the training comprising: providing a background audio signal and a target audio signal using the audio output, the target audio signal at least partially overlapping with the background audio signal, and the target audio signal defining information to be determined by a user; wherein one or both of the background audio signal and target audio signal comprise binaural audio; receiving, at the user interface, a user input corresponding to a user assessment of the information defined by the target audio signal; and providing feedback to the user based on the user assessment indicated by the user input.
Patent AU-2022270398-A1 (AU)
Title: Two-layer multi-strand cable having improved surface fracture energy
Inventor: CHEVALLEY MARIANNA
IPC: B60C9/00
Filed: 2022-04-11
Abstract: The invention relates to a multi-strand cable (50) comprising: an inner cable layer (Cl) consisting of K=1 inner strand (Tl) having three layers (C1, C2, C3), namely an inner layer (C1) consisting of Q inner metal wires (F1), an intermediate layer (C2) and an outer layer (C3) consisting of N outer metal wires (F3); and an outer cable layer (CE) consisting of L>1 outer strands (TE) having three layers (C1', C2', C3'), wound around the inner cable layer (Cl), namely an inner layer (C1') consisting of Q' inner metal wires (F1'), an intermediate layer (C2') consisting of M' intermediate metal wires (F2') and an outer layer (C3') consisting of N' outer metal wires (F3'). The cable (50) has a surface fracture energy ES ≥ 180 N.mm-1 with ES= (I), wherein (II) is the sum of the forces at fracture for Nc wires, (III) is the sum of the total elongation of the Nc wires, Cfrag is the weakening coefficient of the cable (50), and D is the diameter of the cable (50).
Patent AU-2022270773-A1 (AU)
Title: Field monitoring and data collection systems and methods for a precision agriculture system
Inventor: PORTH CHRISTOPHER BROCK
IPC: G01D21/00
Filed: 2022-05-02
Abstract: A sensor network for measuring and processing agricultural sensor measurements having multi-depth sensors, field monitors, and/or field data collection systems. The multi-depth sensor having a GPS; sets of physical sensors located at different depths; a processing structure sampling measurements from the physical sensors; and storing the measurements. The field monitor for use with a mobile platform having: a housing; a camera; a LiDAR sensor; a processing structure capturing point data and image data; generating above-ground field data; and determining crop data. The field data collection system having a stationary field monitor and one or more mobile field monitors capturing above-ground data. The stationary field monitor and the mobile field monitors having an associated GPS. The multi-depth sensors capture below-ground data and communicating the below-ground data to the stationary field monitor. A GPU processes the above-ground data and the GPS data to generate a point cloud data set.
Patent AU-2022271408-A1 (AU)
Title: Cryptographic data transfer
Inventor: WILSON ROBERT
IPC: G06Q20/08
Filed: 2022-11-15
Abstract: The present invention relates to a digital transaction apparatus including a Data Assistance 
Device (DAD) including, a user interface that is operable to at least select data, and a DAD 
transmitter, a Digital Transaction Card (DTC), including a Digital Transaction Processing Unit 
(DTPU), and a DTC receiver, wherein the DAD and DTC are operable to transfer data from the 
DAD to the DTC and when subsequently using the DTC to effect a digital transaction, the DTC 
operates in accordance with the data selected and transferred from the DAD to the DTC, the DAD 
being further operable to perform at least one DAD encryption upon data transferred to the DTC, 
each of the at least one DAD encryption selected from one or more cryptographic schemes, the 
DTC further operable to perform at least one DTC decryption upon received DAD encrypted data.
Patent AU-2022279876-A1 (AU)
Title: Antibody specifically binding to asm protein
Inventor: HONG SEUNG BEOM
IPC: C07K16/40
Filed: 2022-05-26
Abstract: The present invention relates to an antibody specifically binding to an acid sphingomyelinase (ASM) protein. Particularly, the antibody or an antigen-binding fragment thereof, according to the present invention, specifically binds to the ASM protein, with high binding affinity, and, thus, can be effectively used for detecting the ASM protein or diagnosing, etc. a disease occurring due to overexpression of the ASM protein.
Patent AU-2022291615-A1 (AU)
Title: Apparatus and Method for Treating Intestinal Disorder
Inventor: FORSELL PETER
IPC: A61N1/36
Filed: 2022-12-23
Abstract: An apparatus for treating a patient having a disorder related to the passageway of the 
patient's intestines, such as constipation or incontinence, comprises a pump for implantation 
in the patient operable on at least one selected portion of the intestines to pump intestinal 
contents through the passageway of the intestines. The pump includes a constriction device 
for alternately constricting the selected portion to at least substantially reduce the volume of 
the passageway of the intestines along the selected portion and to release the selected 
portion to increase the volume of the passageway of the intestines along the selected 
portion, such that intestinal contents is displaced through the passageway of the intestines.
Patent AU-2022291863-A1 (AU)
Title: Precision medicine for schizophrenia and psychotic disorders: objective assessment, risk prediction, pharmacogenomics, and repurposed drugs
Inventor: NICULESCU ALEXANDER BOGDAN
IPC: A61P25/18
Filed: 2022-06-17
Abstract: Disclosed are novel compounds for treating and preventing schizophrenia, and more generally psychosis, by bioinformatics drug repurposing using novel genes expression biomarkers involved in psychotic symptoms (delusions, hallucinations); methods for assessing severity, determining future risk, matching with a drug treatment, and measuring response to treatment, for psychosis in a subject; and method of using repurposed drugs and natural compounds to prevent and to treat psychosis. Methods are disclosed using a universal approach, in everybody, as well as personalized approaches by gender. The discovery describes compounds for use in everybody (universal), as well as personalized by gender (males, females). Methods for identifying which subjects should be receiving which treatment, using genes expression biomarkers for patient stratification and measuring response to treatment. The disclosure also relates to algorithms. The algorithms combine biomarkers as well as clinical measures for psychosis, to identify subjects who are at risk of psychosis, and to track responses to treatments.
Patent AU-2022293611-A1 (AU)
Title: N-substituted phenylsulfonamide compound and use thereof
Inventor: WANG YOUXIN
IPC: C07D307/52
Filed: 2022-06-10
Abstract: The present invention relates to an N-substituted phenylsulfonamide compound and a use thereof. Specifically, the present invention provides a compound represented by formula I, or an optical isomer thereof, or a racemate thereof, or a pharmaceutically acceptable salt thereof. The compound described in the present invention has an excellent inhibitory effect on transient receptor potential channel proteins, and has an excellent therapeutic effect on transient receptor potential channel protein-related diseases, such as inflammatory bowel disease, irritable bowel syndrome, pain, and inflammation.
Patent AU-2022301201-A1 (AU)
Title: A method for identifying variants in gene products from gene constructs used in cell therapy applications
Inventor: ANDRADE JORGE
IPC: G16B30/00
Filed: 2022-06-29
Abstract: A method for ensuring that gene products used in cell therapy do not carry a risk of reduced efficacy or toxicity due to production of unintended variants. The method includes performing an in-silico analysis on the gene construct to identify and alter sequences likely to cause variants. Also, the method includes performing an in-vivo analysis consisting of RNA-sequence of construct based products. Variant detection may then be performed based on gapped reads from the RNA-sequence to determine variant expression levels, variant significance. The method may include repeating the in-silico analysis if identified variants are unacceptable.
Patent AU-2022378001-A1 (AU)
Title: Warehousing system and method
Inventor: WANG XU
IPC: B65G1/04
Filed: 2022-10-09
Abstract: Provided in the present disclosure are a warehousing system and method. The warehousing system comprises: a workstation, which comprises at least one picking station and at least one distributing station, the picking station and the distributing station being used for processing a container; a movable carrier stop area, which is used for stopping a conveyance apparatus for bearing a movable carrier and is equipped with a container handling apparatus; the conveyance apparatus, which is responsible for conveying the movable carrier to the movable carrier stop area and is used for bearing the container; and the container handling apparatus, which is responsible for moving the container between the workstation and the movable carrier. Both the picking station and the distributing station are arranged at the workstation, so that the moving distance of an operator or an automatic apparatus from the picking station to the distributing station can be reduced, so as to effectively improve the picking efficiency.
Patent WO-2024000019-A1 (WO)
Inventor: BUTLER GREGORY DEAN
IPC: C10G1/10
Filed: 2023-06-27
Abstract: A system for recycling end-of-life rubber or plastics materials is disclosed. The system comprises a pyrolysis apparatus configured to subject the end-of-life rubber or plastics material to a pyrolysis reaction under conditions to produce a first carbon black product and a liquid or gaseous hydrocarbon transition feedstock. The system also comprises a separator for separating the liquid or gaseous mixed hydrocarbon transition feedstock from the pyrolysis reaction. The system further comprises a decarbonisation apparatus configured to treat the mixed hydrocarbon transition feedstock under conditions to produce hydrogen and a second carbon black product.
Patent AU-2023201831-A1 (AU)
Title: Device and method for handling a multi-cell scheduling
Inventor: LEE CHIEN-MIN
IPC: H04W72/12
Filed: 2023-03-23
Abstract: of Disclosure 
A communication device for handling a multi-cell scheduling 
includes at least one storage device; and at least one 
5 processing circuit, coupled to the at least one storage 
device, wherein the at least one storage device stores 
instructions, and the at least one processing circuit is 
configured to execute the instructions of: receiving a 
downlink (DL) control information (DCI) from a network; 
o determining a plurality of first cells for at least one 
communication operation from a cell set according to the DCI; 
and performing the at least one communication operation with 
the network via at least one cell of the plurality of first 
cells.  
5
3/8 
30 
300 
Start 
302 
Receive a DCI rom a network 
Determine a plurality of first cells for at least 304 
one communication operation from a cell set 
according to the DCI 
Perform the at least one communication 306 
operation with the network via at least one cell 
of the plurality of first cells 
308 
End 
FIG. 3
Patent AU-2023202206-A1 (AU)
Title: Prefabricated shelf
Inventor: YOON HYO SANG
IPC: A47B47/00
Filed: 2023-04-11
Abstract: Proposed is prefabricated furniture and, more particularly, 
to a prefabricated shelf (angle) having assembly holes and 
assembly protrusions for assembling frames together, the frames 
being more firmly assembled as a pressing protrusion portion 
protrudes from a narrow portion of an assembly hole so that an 
assembly protrusion is forcibly fitted by the pressing 
protrusion part. The prefabricated shelf includes a first 
frame in which a pair of assembly holes, each having a wide 
portion and a narrow portion, are arranged symmetrically, and a 
second frame in which a pair of assembly protrusions, 
corresponding to the assembly holes and each protruding to fit 
into the narrow portion, are arranged symmetrically, wherein 
the narrow portion includes a pressing protrusion portion 
configured to protrude from a first end thereof and press the 
assembly protrusion to a second side thereof to force the 
assembly protrusion into place.
1/9 
FIG.I1 
20 
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D24 i 
21 IiIf 
Iiif
Patent AU-2023203169-A1 (AU)
Title: Chimeric and humanized anti-human CTLA4 monoclonal antibodies and uses thereof
Inventor: LIU YANG
IPC: C12P21/08
Filed: 2023-05-19
Abstract: This invention relates to compositions of chimeric and humanized antibodies that bind to 
the human CTLA4 molecule and their use in cancer immunotherapy and for reduction of 
autoimmune side effects compared to other immunotherapeutic agents.
Patent AU-2023203393-A1 (AU)
Title: Compositions and methods for screening and identifying clinically aggressive prostate cancer
Inventor: HUTTENHOWER CURTIS
IPC: C12Q1/02
Filed: 2023-05-31
Abstract: The present invention provides methods for screening and diagnosing prostate cancer based 
on a correlation between cancer cell growth, cancer lethality or recurrence and the expression 
level of ZFP36 or NEDD9 and PTEN in conjunction with ZFP36. The disclosure also 
provides methods for screening and diagnosing prostate cancer based on a correlation 
between cancer lethality and the genotype of rs1910301 SNP. Also provided are methods for 
treating prostate cancer comprising providing a treatement or monitoring based on the 
expression level of ZFP36, the expression level of NEDD9, and the expression level of 
ZFP36 in conjunction with PTEN levels or the genotype of rs1910301 SNP.
Patent AU-2023203531-A1 (AU)
Title: Self-tensioning magnetic tracks and track assemblies
Inventor: JAMES ARTHUR
IPC: E06B9/00
Filed: 2023-06-06
Abstract: A magnetic track assembly including an elongate channel having an open side, an end wall, 
and two parallel side walls; a first magnet disposed within the elongate channel near an 
interior side of the end wall; a compartment defined within the elongate channel spaced from 
the first magnet; and a screen receiver disposed within the compartment and including a 
second magnet arranged facing the first magnet. In the magnetic track assembly, the first 
and second magnets are of opposite polarity and the screen receiver is loosely disposed 
within the compartment such that a magnetic bond is intact between the first and second 
magnets when the first and second magnets are close together and the magnetic bond is 
broken when the first and second magnets are pulled apart.
Patent WO-2012040798-A1 (WO)
Title: Semelle élastique pour éléments en béton sur lesquels reposent les rails d'une voie ferrée
Inventor: CARELS PATRICK
IPC: E01B3/46
Filed: 2011-09-27
Abstract: La présente invention se rapporte à une semelle élastique dotée d'un élément en béton (5) sur lequel reposent les rails (6) d'une voie ferrée, la semelle élastique comprenant une couche de fixation (3) et une couche élastique (2), la couche de fixation (3) étant pourvue de filaments montants (4) qui sont au moins en partie encastrés dans l'élément en béton (5).
Patent WO-2008134830-A1 (WO)
Title: Procédé pour obtenir le lipide monophosphorylé a à partir de bordetella pertussis comme sous-produit de la production du vaccin cellulaire anti-coquelucheux
Inventor: RAW ISAIAS
IPC: C07H13/06
Filed: 2007-03-22
Abstract: L'invention porte sur un procédé pour obtenir le Lipide monophosphorylé A à partir de Bordetella pertussis (BpMPLA), comme sous-produit de la production du vaccin cellulaire anticoquelucheux, en vue d'une utilisation dans des applications immunostimulantes telles qu'un adjuvant de vaccin, et, plus particulièrement, sur un procédé de purification de BpMPLA à partir du traitement d'un extrait alcoolique, d'un surnageant ou d'un filtrat habituellement rejeté provenant de la masse finale du vaccin contre Bordetella pertussis (sous-produit de la fabrication du vaccin principal). Ce procédé de purification de BpMPLA comprend le traitement d'un extrait alcoolique habituellement rejeté et provenant de la masse finale du vaccin contre Bordetella pertussis, les opérations consistant à soumettre cette masse finale à une colonne d'affinité et à soumettre la fraction éluée par détergent à une hydrolyse acide, suivie d'une neutralisation, d'une lyophilisation et d'une remise en suspension avec de l'eau pour injection plus un détergent doux. Le nouveau BpMPLA est utilisé dans des applications immunostimulantes, plus particulièrement, en tant qu'adjuvant de vaccin, et, de façon encore plus particulière, en tant qu'adjuvant pour le vaccin contre la grippe, avec des résultats prometteurs.
Patent WO-2008095268-A1 (WO)
Title: Machine à fabriquer de la glace
Inventor: BORTOLETTO ANDERSON
IPC: F25C1/08
Filed: 2007-11-01
Abstract: L'invention concerne un machine à fabriquer de la glace équipée d'un réservoir de formation de la glace (2), d'un réservoir auxiliaire (6) et d'une zone de stockage de la glace (5). Une partie intérieure du réservoir (2) possède un élément de transport (16), un soc (4) pourvu d'un mouvement angulaire et un évaporateur à doigts (3) formant des morceaux de glace. Pendant le procédé de fabrication de la glace, le soc (4) se déplace périodiquement à de faibles fréquences de manière à attirer les particules d'impureté et les sels d'eau, les maintenant éloignés des zones de formation des morceaux de glace. La machine selon l'invention permet de produire des morceaux de glace sans impuretés.