baber/WOPTO huggingface dataset:
Patent CA-2135787-A1 (CA)
Title: Polypeptide bombesin antagonists
Inventor: SCHALLY ANDREW VICTOR
IPC: A61K38/08
Filed: 1994-03-07
Abstract: Pseudopeptides comprising a peptide of formula (I): X-A1-A2-Trp-Ala-Val-Gly-His-Leu-psi-A9-Q wherein X is hydrogen, a single bond linking the alpha amino group of A1 to the gamma carboxyl moiety on the 3-priopionyl moiety of A2 when A2 is Glu, or a group of formula R1CO- wherein Ri is selected from the groups consisting of: a) hydrogen, C1-10alkyl, phenyl or phenyl-C1-10-alkyl, p-H1-phenyl, p-H1-phenyl-C1-10-alkyl, naphthyl, naphthyl-C1-10-alkyl, indolyl, indolyl-Cl1-10-alkyl, pyridyl, pyridyl-C1-10,-alkyl, thienyl, thienyl-C1-10-alkyl, cyclohexyl or cyclohexyl-C1-10-alkyl, where H1 = F, Cl, Br, OH, CH3 or OCH3;  b) N(R2)(R3)-, wherein R2 is hydrogen, C1-10alkyl, phenyl or phenyl-C1-10-alkyl, R3 is hydrogen or C1-10alkyl; c) R4O-, wherein R4 is C1-10alkyl, phenyl or phenyl-C1-10-alkyl; A1 is a D- or L-amino acid residue selected from the group consisting of Phe, p-H1-Phe, pGlu, Nal, Pal, Tpi, unsubstituted Trp or Trp substituted in the benzene ring by one or more members selected from the group consisting of F, Cl, Br, NH2 or C1-3alkyl; or A1 is a peptide bond linking the acyl moiety of R1CO- to the alpha amino moiety of A2; A2 is Gln, Glu[-], Glu(Y) or His, wherein [-] is a single bond linking the gamma carboxyl group of A2 when A2 is Glu with the alpha amino group of A1 where X  is a single bond, Y is -OR5 or -N(R5)(R6) wherein R5 is hydrogen, C1-3alkyl or phenyl; R6 is hydrogen or C1-3alkyl; and R7 is hydrogen, C1-3alkyl or -NHCONH2; Leu-psi- is a reduced form of Leu wherein the C = O moiety of Leu is instead -CHr such that the bond of this -CHr moiety with the alpha amino moiety of the adjacent A9 residue is a pseudopeptide bond; A9 is Tac, MTac, or DMTac; and Q  is NH2 or OQ1 where Q1 is hydrogen, C1-10alkyl, phenyl or phenyl-C1-10-alkyl; and the pharmaceutically acceptable acids or salts thereof.
Patent CA-2136907-A1 (CA)
Title: Wheel for in-line skates
Inventor: BOYER GEOFFREY
IPC: A63C17/22
Filed: 1994-11-29
Abstract: An improved wheel for an in-line skate, comprising a hub for rotation about an axis, a circular ring made of a relatively hard material disposed concentrically about the hub,  the ring having an outer ground engaging peripheral surface, and a core disposed concentrically about the hub for at least partially supporting the ring in a ground engaging position thereof, the core having an outer ground engaging peripheral surface and being made of softer material compared to the ring, and wherein the diameter of the ring exceeds the diameter of the core to provide a discrete radial transition from the ground engaging surface of the core to the ground engaging surface of the ring.
Patent CA-2138289-A1 (CA)
Title: N-substituted azabicycloheptane derivatives, the preparation and use thereof
Inventor: STEINER GERD
IPC: C07D409/06
Filed: 1993-06-08
Abstract: Compounds having formula (I), in which R1, R2, n, R3, A, X, Y and Z have the meaning given in the description, are disclosed, as well as their preparation. These new compounds are useful for controlling diseases.
Patent CA-2138972-A1 (CA)
Title: Mixing faucet
Inventor: ENOKI MASATOSHI
IPC: F16K27/04
Filed: 1994-04-20
Abstract: A hot and cold water mixing device which comprises one or more valve units each constituted by accommodating an operating member within a hollow casing, and a housing into which the one or more valve units are inserted and arranged and in which two primary water passages communicating with a hot water supply source and a cold water supply source, respectively, are formed.  The housing is composed of an outer housing  (1)  and an  inner housing  (2)  which is inserted into the outer housing and which is formed with water holes (11,12,13) communicating with said valve units, and at least two primary water passages (5,6) are formed between  the  outer  housing  and  the  inner  housing  by separating members  (3).   Further,  since the hot water passage (5) and the cold water passage (6) are formed between the outer casing (1) and the inner housing (2) using separating members (13), the primary water passages can easily be formed and, simultaneously, the construction of the mixing device can be simplified and the assembling and disassembling operations can be facilitated.
Patent CA-2139550-A1 (CA)
Title: Bone anchor implantation device
Inventor: BENDEREV THEODORE V
IPC: A61B19/08
Filed: 1993-04-05
Abstract: A suture passer is provided comprising an elongate tubular probe guide (125) extending in a distal direction from a handle (110). An elongate pointed probe (115) is disposed to be axially movable within the tubular probe guide (125). A recess (160) is provided on the probe (115) and an opening (130) is provided on the tubular probe guide (125) for receiving a suture. The probe (115) may be moved axially with respect to the probe guide (125) such that the recess (160) aligns with the opening (130) for receiving the suture. In a second position, the recess (160) is moved out of alignment with the opening (130) to trap the suture within the recess.
Patent CA-2141417-A1 (CA)
Inventor: EPPENBERGER URS
IPC: G01N33/577
Filed: 1994-06-17
Abstract: La mammamoduline (MM), une nouvelle protétine de 52-55 kDa exprimée par les cellules tumorales mammaires hormono-indépendentes, s'est avérée avoir une influence sur la morphologie, la motilité, le développement et l'expression du récepteur hormonal des cellules tumorales mammaires hormono-dépendentes. La présence de MM, par exemple dans des biopsies tumorales, est un indicateur de diagnostique important. Les inhibiteurs de l'activité de MM, tels que des anticorps monoclonaux MAbs contre la MM et des antagonistes de MM, sont utiles dans le traitement et la lutte contre le cancer du sein.
Patent CA-2142707-A1 (CA)
Title: Benzo-Fused Lactams Promote Release of Growth Hormone
Inventor: BOCHIS RICHARD J
IPC: A61K38/25
Filed: 1993-08-18
Abstract: PCT No. PCT/US93/07791 Sec. 371 Date Apr. 18, 1995 Sec. 102(e) Date Apr. 18, 1995 PCT Filed Aug. 18, 1993 PCT Pub. No. WO94/05634 PCT Pub. Date Mar. 17, 1994There are disclosed certain novel compounds identified as benzo-fused lactams which promote the release of growth hormone in humans and animals. This property can be utilized to promote the growth of food animals to render the production of edible meat products more efficient, and in humans, to increase the stature of those afflicted with a lack of a normal secretion of natural growth hormone. Growth promoting compositions containing such benzo-fused lactams as the active ingredient therefore are also disclosed.
Patent CA-2143323-A1 (CA)
Title: Herbicidal 2-[(Heterocyclic-Phenoxymethyl)Phenoxy] -Alkanoates
Inventor: THEODORIDIS GEORGE
IPC: C07D513/04
Filed: 1993-08-25
Abstract: Herbicidal compounds, compositions containing them, and a method for controlling weeds by application of the compositions are disclosed. The herbicidal compounds are 2-[(4-heterocyclic-phenoxymethyl)phenoxy]alkanoates of the formula   <IMAGE>   in which A is a derivative of an alkanoate bonded to the phenoxy oxygen at the alpha carbon, and Q is 4-difluoromethyl-4,5-dihydro-3-methyl-l,2,4-triazol-5(1H)-on-1-yl, 3,4,5,6-tetrahydrophthalimid-1-yl, 1-(1-methylethyl)imidazolidin-2,4-dion-3-yl, 1,4-dihydro-4-(3-fluoropropyl)-5H-tetrazol-5-on-1-yl, 3-chloro-4,5,6,7-tetrahydroindazol-2-yl, 4-methyl-l,2,4-triazine-3,5-dion-2-yl, 8-thia-1,6-diazabicyclo[4.3.0]-nonane-7-on-9-ylimino, or 1-methyl-6-trifluoromethyl-2,4-pyrimidinedione-3-yl; X is hydrogen, methyl, fluorine, or chlorine; Y is hydrogen; W is oxygen or sulfur; Z is hydrogen, fluorine, chlorine, bromine, lower alkyl, or methoxy; Z' is hydrogen, fluorine, or chlorine; and the group AO- may be in the 2, 3, or 4-position of the phenyl ring.
Patent CA-2147744-A1 (CA)
Title: A process for the production of washing- or cleaning-active extrudates
Inventor: JACOBS JOCHEN
IPC: C11D17/06
Filed: 1993-10-14
Abstract: High-density extrudates are produced under pressure, with a homogenous solid premix being pressed into a strand at these pressures and, following extrusion, the strand being cut up by a cutter to the predetermined granulate size, but with no essential increase in the pressure and thus in the specific work as the throughput is increased. This is accomplished by using in the extru-sion premix a self-regulating system consisting of preparation constituents having intrinsically viscous effects and preparation constituents having dilatant effects. Since, in macroscopic terms, there is no change in the pressure in the compound sufficient to effect an essential change in the specific work, the extrusion throughput can be increased in a given system with approximately the same temperature or in the same temperature range as before the increase in throughput (approximate constancy of tempera-ture). As a result, temperature-sensitive constituents, for example peroxy bleaching agents, can also be extruded despite the in-crease in throughput.
Patent CA-2153103-A1 (CA)
Inventor: DOWN JAMES A
IPC: C12Q1/6806
Filed: 1995-06-30
Abstract: The invention provides a rapid process for lysing Mycobacteria. In one embodiment is provided a process for lysing Mycobacteria which comprises exposing the bacteria to a lysis effective amount of heat. A particularly effective method for providing the necessary heat is in the form of forced hot air such as in a forced hot air oven. The process of the invention is particularly advantageous since only one step is involved, it is expedient compared to prior methods, and little instrumentation is necessary. By practicing the present invention it is possible to lyse Mycobacteria with minimal effort. In addition, practicing the invention results in liberating cellular components including deoxyribonucleic acid (DNA) from Mycobacteria. Not only is DNA liberated, but the DNA is suited for subsequent analysis by way of probe hybridization, restriction enzyme analysis, and the like.
Patent CA-2153495-A1 (CA)
Title: Biodegradable thermoplastic polymer blend compositions with accelerated biodegradation
Inventor: LOOMIS GARY L
IPC: C08F/
Filed: 1994-01-06
Abstract: Biodegradable thermoplastic polymer blend compositions are presented in which a first polymer and a second polymer are intimately associated together in a uniform, substantially homogeneous blend. The second polymer of the composition acts to facilitate biodegradation of the composition, and of shaped articles manufactured therefrom, at a rate which is enhanced over that of the most slowly biodegrading individual polymer component of the composition. The composition may further comprise a polysaccharide component, such as a starch component like destructurized starch.
Patent CA-2154219-A1 (CA)
Title: Plasma-addressed display device
Inventor: SEKI ATSUSHI
IPC: H01J17/49
Filed: 1995-07-19
Abstract: A plasma-addressed display device comprises a first substrate having a number of first electrodes arranged alternately in parallel on a main surface,  a second substrate having a number of second electrodes orthogonal with  respect  to  the  first  electrodes  and  arranged alternately in parallel, with the second electrodes facing the first electrodes, a dielectric sheet interposed between the  first  and second substrates,  an electro-optical substance for maintaining a space between the dielectric sheet and the first substrate and a underlying layer formed between the second substrate and the second electrodes, so that warping of the glass substrate of the plasma cell side may be suppressed and substrate discharge within the plasma cell may be controlled.
Patent CA-2154249-A1 (CA)
Inventor: KOTZER MOSHE
IPC: B29C48/09
Filed: 1994-03-23
Abstract: A technique for extrusion of plastic including a first step of extruding which includes extruding at least one layer of a thermally cross-linkable material in an extrusion apparatus (20) having at least one die wall (22); a second step of extruding, performed simultaneously with the first step of extruding, and which includes extruding at least one layer of thermoplastic material in the extrusion apparatus between the thermally cross-linkable material and the at least one die wall (22) and heating the thermally-cross-linkable material thereby to provide at least a predetermined minimum rate of cross-linking thereof during the steps of extrusion of the plastic.
Patent CA-2154685-A1 (CA)
Title: Pressure regulator
Inventor: EIDSMORE PAUL G
IPC: F16K17/30
Filed: 1994-02-01
Abstract: A pressure regulator includes a housing hav-ing a chamber that receives a pressure responsive member (30). The pressure responsive member (30) includes an internal charge (90) that allows a movable portion (68) of the regulator to react in response to pressure differentials.  A preferred embodiment of the regulator includes a dampening member defined by an o-ring (82) that exerts a drag on the pressure responsive member (30) to address oscillations associated with high flow rates. The dampening force can be varied according to the sub-ject invention. Moreover, a normally planar poppet retaining member reduces manufacturing costs of the regulator and allows for a highly polished sur-face to address concerns with impurities.  A biasing arrangement (120) is also incorporated into the reg-ulator to assure that the poppet (68) seals against the valve seat (70) if the internal pressure charge of the regulator is lost.
Patent CA-2155095-A1 (CA)
Title: Unsaturate amino compounds for use as anticancer and antiprotozoic agent
Inventor: FREI JOERG
IPC: C07C211/22
Filed: 1994-12-14
Abstract: The invention relates to compounds of formula (I), wherein R1 and R2, each independently of the other, are selected from lower alkyl that is unsubstituted or substituted by one or more fluorine atoms which are not linked to the carbon atom of R1 or R2 bonding the nitrogen; from lower alkenyl wherein the double bond does not originate from the carbon atom that is bonded to a nitrogen bonding R1 or R2; from lower alkynyl wherein the triple bond does not originate from the carbon atom that is bonded to a nitrogen bonding R1 or R2; from cycloalkyl; and from cycloalkyl-lower alkyl; with the proviso that not more than one of the two radicals R1 and R2 is methyl; or salts thereof. The mentioned compounds are pharmacologically active against disorders that are responsive to a recuction in intracellular polyamines, such as tumours or protozoal diseases.
Patent CA-2156182-A1 (CA)
Inventor: HOOSER STEVEN M
IPC: B23D61/04
Filed: 1994-02-25
Abstract: A rotary cutter grinder that cuts and grinds upon its circumferential surface is well suited for stump grinding and the like appli-cations. The rotary cutter grinder is consti-tuted by a hub portion (12) for mounting to the power output shaft of a prime mover and plu-ral (18, 20) arms unitary with the hub portion. These arms are substantially uniformly spaced about the hub portion and extend radially out-wardly therefrom. A cutting tool (26), usually a tungsten carbide cutting tool, is mounted to each of the arms at a positive rake angle rel-ative to the perpendicular to the direction of motion by the cutting tool.
Patent CA-2160755-A1 (CA)
Title: Method for making a substituted benzene compound
Inventor: SPANGLER LORI ANN
IPC: C07C303/22
Filed: 1995-10-17
Abstract: A method for making a substituted benzene compound includes reacting a 2-substituted benzenesulfonate or the 2-substituted benzenesulfonate further substituted in the 3, 4 or 5-position with a lithium compound to form an intermediate; and reacting the intermediate with an electrophile to form a 2,6-disubstituted benzenesulfonate or a 2,6-disubstituted benzenesulfonate further substituted in the 3, 4 or 5-position.
Patent CA-2163392-A1 (CA)
Title: Oligoribonucleotides with amide backbone
Inventor: LI WEN-REN
IPC: C07H19/167
Filed: 1995-11-21
Abstract: Oligomers having amide linkages of the following formula:       wherein R1 is H, C1-4 alkyl, C1-18-acyl or hydroxy-lower alkyl; R2 is H, aralkyl, or C1-4 alkyl; B is a nucleoside base residue selected from the group consisting of adenine, cytosine, guanine, thymine, uracil; X is H, OR1, NHR2 or NH-acyl; Y is OR2 or NHR2; and n is a number from 5 through 25, and salts thereof.
Patent CA-2163804-A1 (CA)
Title: Christmas light assembly
Inventor: CHEN MING-HSIUNG
IPC: H01K7/06
Filed: 1995-11-27
Abstract: A  Christmas light assembly consisting  of  a lamp  base,  which holds the lamp, and  a  lamp  holder, which  holds  the  two metal contact terminals  of  the electric  wire, wherein the lamp base has  an  oval-like top ring, two smoothly curved symmetrical walls and  two downward hooks extended from the oval-like top ring  and defining a jack for holding the lamp, the oval-like  top ring  defining a major axis bigger than the upper  limit of the manufacturing tolerance of the outer diameter  of the  lamp  and a minor axis slightly  smaller  than  the lower  limit of the manufacturing tolerance thereof  for flexibly  fitting the actual outer diameter of the  lamp installed; the lamp holder has two longitudinal  outside grooves  terminating in a respective retaining  portions for engagement with the downward hooks of the lamp base, and  two  terminal chambers to hold  the  metal  contact terminals  in such a position that the smoothly  curved symmetrical  walls are compressed inwards by  the  metal contact terminals to hold  down the  lamp upon the insertion of the smoothly curved symmetrical walls  into the lamp holder.
Patent CA-2164307-A1 (CA)
Inventor: BURKE TREVOR JOHN
IPC: G06F17/30
Filed: 1994-06-03
Abstract: Dans un système d'extraction de données, on peut enregistrer ces données à extraire dans la mémoire d'un ordinateur central, et on peut accéder à celles-ci à partir de terminaux d'utilisateurs qui transmettent les demandes de données à l'ordinateur central. Les données sont enregistrées dans l'ordinateur central sous la forme d'une série de termes de recherche agencés dans un ordre logique prédéterminé, et chaque terme de recherche enregistré avec des données associées auxquelles des utilisateurs demandent l'accès. Des demandes d'extraction de données sont entrées par des utilisateurs sous la forme de termes de recherche correspondant, en structure logique, aux termes de recherche mémorisés dans l'ordinateur central. La mémoire de l'ordinateur central est divisée en une série de blocs où sont mémorisés, dans chacun, à la fois les termes de recherche rentrant dans une plage prédéterminée respective de l'ordre logique et les données associées à ces termes de recherche. Chaque terminal d'utilisateur possède une mémoire dans laquelle est mémorisé un indice qui établit des correspondances de l'adresse de mémoire de chaque bloc dans la mémoire centrale avec la plage de termes de recherche enregistrés dans ce bloc. Chaque terminal d'utilisateur répond à l'entrée d'un terme de recherche en identifiant à partir de l'indice l'adresse de mémoire du bloc mémorisant la plage de termes de recherche, y compris le terme de recherche introduit, et transmettant l'adresse de mémoire identifiée à l'ordinateur central. L'ordinateur central répond en transmettant le contenu du bloc identifié, par une adresse de mémoire réceptionnée, au terminal de l'utilisateur à partir duquel l'adresse de mémoire réceptionnée à été transmise. Chaque terminal d'utilisateur affiche des données qui lui ont été transmises à partir de l'ordinateur central afin de lui permettre de sélectionner les données d'intérêt à partir du contenu du bloc réceptionné.
Patent CA-2164962-A1 (CA)
Title: Bicycle torque coupling
Inventor: SMILANICK STEVE FRANK
IPC: B62K11/02
Filed: 1994-07-12
Abstract: A torque transmitting, bicycle frame coupling (50) is provided which connects to the frame tubes (1, 11) of a bicycle. The coupling (50) replaces a portion of the tubes (1, 11) and has clutch teeth (3, 7) on their engaging faces. Each coupling (50) is actuated, pulling the tubes (1, 11) together and joining them through use of specialized clutch teeth (3, 7) under compression provided by a threaded lug (2), a removable-shoulder lug (9) with a removable shoulder (4) and a threaded coupling nut (5). The removable shoulder (4) makes the nut (5) and shoulder replaceable, and makes possible an additional shoulder (10) on the tube connecting end of the removable-shoulder lug (9) to keep the nut (5) from slipping onto the tube (11).
Patent CA-2166088-A1 (CA)
Title: Coupling Mechanism for Quickly Axially Aligning Rotor to Journals
Inventor: POSCICH DOUGLAS V
IPC: F16D1/04
Filed: 1994-06-29
Abstract: A coupling mechanism for coaxially coupling a rotor body (16) to a journal (24), comprises a split ring collar (38) and a clamping ring (40) with chamfered inner surfaces (64, 72) mating with oppositely inclined outer chamfered surfaces (50, 52) on a split ring (36), the collar (38) and clamping ring (40) being axially secured to act on the split ring (36) and thereby produce a radially inward force on the end portions of the rotor body (16) and journal (24).
Patent CA-2166286-A1 (CA)
Title: Level gravity conveyor with gravity return of transfer units
Inventor: HAMMOND THEODORE A
IPC: B65G1/08
Filed: 1994-06-30
Abstract: A level gravity conveyor (11) provides a plurality of individual load-engaging support pads (44) aligned longitudinally along the conveyor. The pads are movably supported on runway segments (34) which extend longitudinally.  Each runway segment defines an upper raceway surface (41) which movably supports the pad, which upper surface in the preferred embodiment is defined by a plurality of support rollers (41). The runway segments (34) are alternately raised and lowered so that, when in a raised position, the upper surfaces slope downward by gravity along the inclined upper surfaces to forwardly advance the loads through a small distance. When the runway segments (34) are lowered so that the pads disengage the loads, the upper raceway surfaces (41) slope downwardly in the upstream direction to cause gravity-induced return movement of the pads (44) to their original upstream positions.
Patent CA-2169484-A1 (CA)
Title: Rechargeable Non-Aqueous Lithium Battery Having Stacked Electrochemical Cells
Inventor: DASGUPTA SANKAR
IPC: H01M10/04
Filed: 1996-02-14
Abstract: A lithium battery constructed of lithium ion containing folded and stacked electrochemical cells is described, having a folded continuous, flexible lithium ion containing polymer laminate electrolyte sandwiched between first and second polarity lithium containing discrete electrode plates.  The first and second polarity discrete electrode plates are carried, respectively, by first and second electrical current conducting flexible polymer laminates.  The assembled polymer laminates  are  folded  and  stacked,  connected  to  current collectors and packed into a lithium battery case.
Patent CA-2169517-A1 (CA)
Inventor: THURBER JOHN MICHAEL
IPC: A01K87/00
Filed: 1996-02-14
Abstract: An improved fishing rod of the type having a substantially cylindrical body with a peripheral surface.  The improvement is a mark on the body situated so that the circumference of the fishing rod body with the mark thereon simulates the torso of a selected species of fish, with the mark having markings characteristic of markings on the torso of the selected fish species.
Patent CA-2172893-A1 (CA)
Inventor: IKEZAWA HIDEO
IPC: D04H1/425
Filed: 1996-03-28
Abstract: A bio-degradable composite nonwoven fabric for plant cultivation includes a wood pulp paper sheet laminated on a bio-degradable aliphatic polyester filament nonwoven fabric, wherein the polyester filaments and the pulp fibers are entangled to each other and a plurality of spot regions which are spaced from each other, are substantially free from the pulp fibers and have a decreased distribution density of the polyester filaments of 30 to 50%, an area of 0.16 to 16 mm2 and a total area corresponding to 5 to 60% of the total surface area of the composite nonwoven fabric, are formed.  The polyester filament distribution density is defined as the ratio of the total area of the polyester filaments appearing within the spot regions to the total surface area of the spot regions, determined from photographs of the spot regions.