baber/WOPTO huggingface dataset:
Patent CA-2998633-A1 (CA)
Inventor: SCHWAEBLE HANS-WILHELM
IPC: A61P37/02
Filed: 2005-06-09
Abstract: In one aspect, the invention provides methods of inhibiting the effects of MASP-2-dependent complement activation in a living subject. The methods comprise the step of administering, to a subject in need thereof, an amount of a MASP-2 inhibitory agent effective to inhibit MASP-2-dependent complement activation. In some embodiments, the MASP-2 inhibitory agent inhibits cellular injury associated with MASP-2-mediated alternative complement pathway activation, while leaving the classical (C 1 q-dependent) pathway component of the immune system intact.  In another aspect, the invention provides compositions for inhibiting the effects of lectin-dependent complement activation, comprising a therapeutically effective amount of a MASp-2 inhibitory agent and a pharmaceutically acceptable carrier.
Patent CA-2999610-A1 (CA)
Inventor: GOVARI ASSAF
IPC: A61B18/14
Filed: 2018-03-29
Abstract: A medical apparatus, including a probe having a distal end configured for insertion into a body cavity and containing a lumen that opens through the distal end, and an inflatable balloon deployable through the lumen into the body cavity such that when the balloon is deployed through the lumen and inflated, a distal pole on a distal side of the balloon is located opposite the lumen. In embodiments of the present invention, the medical apparatus also includes an electrode attached to the distal side of the inflatable balloon and extending over at least 50% of an area of the distal side of the balloon that is within 30° of arc from the distal pole.
Patent CA-3000622-A1 (CA)
Title: Composition fongicide pour l'agriculture et l'horticulture
Inventor: NISHIMURA SATOSHI
IPC: A01N43/40
Filed: 2016-10-05
Abstract: La présente invention concerne une composition fongicide pour l'agriculture et l'horticulture contenant au moins un composé A choisi dans le groupe constitué par des composés représentés par la formule (1) {dans la formule (1), chaque X représente indépendamment un groupe halogéno ou un groupe alkyle C1-6 ; n représente le nombre de X, et est un entier de 0 à 5 ; X' représente un groupe halogéno ; chaque R1, R2 et R3 représente indépendamment un groupe alkyle C1-6, un groupe alkoxy C1-6 ou un groupe hydroxyle ; et chaque A1 et A2 représente indépendamment un atome d'azote ou un atome de carbone.}, etc., et au moins un composé B choisi dans le groupe constitué par le pydiflumétofène, le pyraziflumid, l'isofetamid, le tolprocarb, le fluxamétamide, le broflanilide, le tiadinil, le fénoxanil, le triflumézopyrime, etc.
Patent CA-3001548-A1 (CA)
Inventor: GIUSEPPIN MARCO LUIGI FEDERICO
IPC: A61K38/56
Filed: 2016-11-04
Abstract: La présente invention concerne un procédé pour réduire le temps de latence dans une fermentation d'un milieu de culture pour préparer une substance cible, la substance cible n'étant pas du yaourt et la fermentation entraînant la formation d'acide ou d'éthanol, lequel procédé comprend les étapes consistant à fournir, à un milieu de culture approprié, une culture de départ de fermentation comprenant un micro-organisme qui libère de l'acide ou de l'éthanol, à ajouter un inhibiteur de protéase de protéine de pomme de terre au milieu de culture, à cultiver le micro-organisme et à obtenir la substance cible. On a découvert que l'addition d'inhibiteur de protéase de protéine de pomme de terre à une alimentation de fermentation réduit sensiblement le temps de latence de la fermentation. L'invention concerne également un produit alimentaire fermenté qui n'est pas du yaourt, comprenant un inhibiteur de protéase de protéine de pomme de terre.
Patent CA-3005725-A1 (CA)
Inventor: GUO JIAN
IPC: G01N33/48
Filed: 2016-12-09
Abstract: The present invention provides a molecular marker CNPY2 isoform 2 for intestinal cancer, which has the sequence identified herein as SEQ ID NO:1. The invention also provides a specific antibody of CNPY2 isoform 2, a kit comprising said specific antibody and a medication for the treatment of intestinal cancer. Further, the present invention also provides a method for detection, diagnosis and prognosis of intestinal cancer and a method for prevention, alleviation and treatment of this cancer.
Patent CA-3005741-A1 (CA)
Title: Compounds and compositions useful for treating disorders related to ntrk
Inventor: WENGLOWSKY STEVEN MARK
IPC: C07D487/04
Filed: 2016-11-18
Abstract: This invention relates to inhibitors of NTRK comprising a pyrazolo[1,5-4]pyrimidine-3-carbonitrile structure. They are active against wild-type NTRK and its resistant mutants.
Patent CA-3006916-A1 (CA)
Inventor: HAWK JEFF
IPC: G10K11/168
Filed: 2018-06-01
Abstract: A sound damping wallboard for installation on an installed wallboard, a sound damping wallboard system, and a method of constructing a sound damping wallboard on a building structure are disclosed. The sound damping wallboard includes a gypsum layer having a gypsum layer inner surface and a gypsum layer outer surface, a first sound damping layer disposed at the gypsum layer inner surface and having a first sound damping layer inner surface opposite the gypsum layer inner surface, a first encasing layer disposed at the gypsum layer outer surface, a second encasing layer disposed at the first sound damping layer inner surface, and a second sound damping layer disposed at the second encasing layer opposite the first sound damping layer inner surface.
Patent CA-3007289-A1 (CA)
Title: Method for lyophilisation of a sample of fecal microbiota
Inventor: AFFAGARD HERVE
IPC: A61K35/37
Filed: 2016-12-19
Abstract: Method for lyophilisation of a sample of fecal microbiota. The present invention relates to a method for lyophilisation of a sample of fecal microbiota from a donor subject, comprising the following steps: A) mixing of a sample of fecal microbiota from a donor subject with a diluent selected from polyols, disaccharides to pentasaccharides, maltodextrins and mixtures thereof, and B) freezing the mixture obtained in A) at a temperature of less than -50°C, preferably of between -70°C and -100°C, followed by the lyophilisation thereof.
Patent CA-3007489-A1 (CA)
Inventor: DROZD ALEKSANDRA
IPC: A61K31/215
Filed: 2016-12-23
Abstract: The present invention relates to an enteric coated oral pharmaceutical preparation in the form of a granulate, a pellet or a mini-tablet comprising dimethyl fumarate and having at least two coating layers, i.e. at least one inner enteric coating layer and an outer coating formed by applying a suspension comprising silicon dioxide on the at least one inner enteric coating layer. The invention relates also to the process for obtaining the enteric coated oral preparation of the present invention and to use of the preparation in the treatment of multiple sclerosis.
Patent CA-3009094-A1 (CA)
Inventor: MCCARTHY STEPHEN J
IPC: B01J29/70
Filed: 2016-11-30
Abstract: Methods are provided for making base metal catalysts with improved activity. After forming catalyst particles based on a support comprising a zeolitic molecular sieve, the catalyst particles can be impregnated with a solution comprising a) metal salts (or other precursors) for a plurality of base metals and b) an organic dispersion agent comprising 2 to 10 carbons. The impregnated support particles can be dried to form a base metal catalyst, and then optionally sulfided to form a sulfided base metal catalyst. The resulting (sulfided) base metal catalyst can have improved activity for cloud point reduction and/or for improved activity for heteroatom removal, relative to a base metal dewaxing catalyst prepared without the use of a dispersion agent.
Patent CA-3011917-A1 (CA)
Title: Method and device for the laying down of a geomembrane
Inventor: SCUERO ALBERTO MARIA
IPC: E02B7/08
Filed: 2017-01-25
Abstract: A method and a device for laying down and sealingly anchoring a waterproofing liner (1) of a synthetic material, on a surface (2) of a hydraulic work (3); the liner (1) is fastened by a plurality of tensioning and anchoring assemblies (4) wherein each assembly (4) comprises a lower metal section bar (5) and an upper metal section (6) each configured with a raised part having side flat surfaces for sealingly clamping the liner (1), wherein the lower section bar (5) has more anchor holes (11) at a plurality of axially spaced apart anchoring zones (21); the surface (2) of the hydraulic work 3) is previously marked by reference marks (19) underlining the presence of possible obstacles such as reinforcement rods near the anchors holes (11) of the anchoring zones (21) of the lower section bar (5); therefore the lower section bar (5) is positioned by aligning the anchor holes (11) to the reference marks (19), anchoring the section bar (5) to the hydraulic work (3) by anchoring devices (10) at least one hole (11) of the anchoring zones (21) wherein there is no obstacle to the insertion of the anchoring devices (10) in the hydraulic work (3). The waterproofing liner (1) is laid down on the surface (2) of the hydraulic work (3), and is sealingly anchored it between the lower section bars (5) and the upper section bars (6) of the tensioning assemblies (4).
Patent CA-3014240-A1 (CA)
Title: Systeme de telescope spherique compact a diffraction limitee pour la detection a distance dans un systeme de satellite
Inventor: HALDEMAN BENJAMIN
IPC: G02B23/06
Filed: 2017-02-17
Abstract: Un mode de réalisation de l'invention concerne un système optique comprenant : une première lentille configurée pour recevoir la lumière entrante en provenance d'un objet ; un premier miroir comprenant une ouverture centrale, le premier miroir étant configuré pour réfracter la lumière provenant de la première lentille, réfléchir la lumière et réfracter la lumière réfléchie par le premier miroir ; un deuxième miroir configuré pour recevoir la lumière provenant du premier miroir, la lumière étant réfractée vers une première surface du deuxième miroir où la lumière est renvoyée et réfractée en sortant du deuxième miroir ; une lentille correctrice négative configurée pour réfracter la lumière provenant du deuxième miroir à travers l'ouverture centrale du premier miroir ; et une lentille correctrice positive configurée pour recevoir la lumière à travers l'ouverture centrale du premier miroir et réfracter la lumière vers une surface de formation d'image.
Patent CA-3016238-A1 (CA)
Inventor: ARTUN LARS
IPC: B32B15/01
Filed: 2017-03-01
Abstract: A method to reduce the total anode mass of a cathodic protection (CP) system by reducing or eliminating the total cathode area is disclosed, the system comprising: a metallic first-layer coating (2) which being anodic to the component or substrate to be protected, bonded to the component or substrate and electrically conductive. A sacrificial anode in the form of a metallic second-layer coating (3) is distributed over the first-layer coating (2). The second layer coating (3) has an open circuit potential that is equal to the first-layer coating or being anodic to the first-layer coating and to the substrate, the second-layer coating (3) electrically conductive, bonded to the first-layer coating (2) and exposed to the surrounding environment.
Patent CA-3017309-A1 (CA)
Inventor: MCHUGH GEORGE J
IPC: F16K24/00
Filed: 2018-09-13
Abstract: A valve assembly includes a pipe fitting through which a gas is configured to flow. The inlet of the pipe fitting is configured to connect to an open port of a fire suppression sprinkler system so that gas flows from the fire suppression sprinkler system into the pipe fitting. The valve assembly also includes a vent valve. The inlet of the vent valve is connected to the outlet of the pipe fitting. The vent valve is operable to move between an open position and a shut position. The valve assembly includes an inert gas analyzer and at least one vent port upstream of the inert gas analyzer. The inert gas analyzer is positioned to measure the inert gas content of gas flowing in front of the inert gas analyzer and through the vent port to an outside environment.
Patent CA-3017410-A1 (CA)
Inventor: FRIMANN MICHAEL
IPC: C25B9/00
Filed: 2017-03-08
Abstract: The present invention relates to a portable electrolyzer (1) comprising an electrolyze chamber (2) with an anode (3) and a cathode (4) as electrodes (3, 4),a membrane (5), a water source (6), such as a water storage vessel (6a), a gas tank(7), a gas compressor (8), an electric power supply (9), and a pulse-width modulator (10), wherein the electrolyzer (1) further comprises i) a thermoelectric cooler (11) attached to the electrolyze chamber (2) and/or a gas tank (7), ii) an ultrasonic generator (12)connected to at least one electrode (3, 4) and/or at least one sonotrode (13), and/or iii) a mixer (14) capable of mixing the aqueous phase inside the electrolyze chamber (2). Claimed further is a process to generate and store hydrogen with the electrolyzer (1) of the invention, the use of the electrolyzer(1) e.g. for welding with a hydrogen flame, to convert electricity from renewable energies into hydrogen and to store said electricity in the form of hydrogen, and/or for heat generation by burning hydrogen in a porous burner. Furthermore, a blowtorch comprising the electrolyzer (1) of the invention is claimed as well.
Patent CA-3018587-A1 (CA)
Inventor: REIDENBERG BRUCE
IPC: A61M25/00
Filed: 2017-03-28
Abstract: La mise en place d'un dispositif d'accès vasculaire (accès vasculaire intraveineux, intra-artériel et/ou intra-osseux) dans un environnement non stérile augmente considérablement le risque d'infection par l'intermédiaire du dispositif d'accès vasculaire. La présente invention concerne une approche pour réaliser une stérilisation du site où un accès vasculaire sera tenté dans des conditions de champ non stériles. De plus, la présente invention concerne un raccord vasculaire stérile préchargé avec un agent antimicrobien, par exemple la Taurolidine. L'utilisation du raccord vasculaire permet, dans le même temps, la fourniture de l'agent antimicrobien et l'obtention d'un accès vasculaire, ce qui limite le risque d'infection malgré le placement de l'accès dans des conditions de champ non stériles.
Patent CA-3021920-A1 (CA)
Inventor: AGARKHED AJIT MANOHAR
IPC: A61Q19/10
Filed: 2017-04-11
Abstract: La présente invention concerne une composition topique. La présente invention concerne plus particulièrement une composition topique apportant des bénéfices antimicrobiens et un procédé de désinfection d'une surface. La présente invention concerne une composition topique comprenant : a) 0,1 à 10 % en masse de Niacinamide ou de ses dérivés ; b) 0,01 % à 5 % en poids d'un premier sel d'ammonium quaternaire comprenant du chlorure de didécyldiméthylammonium; c) 0,01 à 5 % en masse d'un second sel d'ammonium quaternaire ; et d) une base cosmétiquement acceptable.
Patent CA-3022240-A1 (CA)
Title: Systems and methods for detecting fraudulent healthcare claim activity
Inventor: AHMED MUSHEER
IPC: G16H40/00
Filed: 2018-10-26
Abstract: A method and system are provided for detecting fraudulent healthcare claim activity.  An example system includes an analyzer to receive eligibility data related to an interaction between a service provider and a service recipient, and to generate one or more risk scores based on the eligibility data for a subsequent claim submitted based on the eligibility data, the eligibility data being accessed from at least one of a data stream and a storage component; a translator to interpret the one or more risk scores from the analyzer and to generate a user format representative of the one or more risk scores for the subsequent claim; and an interface component to cause a display of the user format.
Patent CA-3022248-A1 (CA)
Inventor: ENGLERT HEIKO
IPC: G01R31/02
Filed: 2018-10-26
Abstract: Method and detection device for detecting a high-impedance ground fault in an electrical energy supply network with a grounded neutral point The invention relates to a method for detecting a high-impedance ground fault in an electrical energy supply network (12) with a grounded neutral point, in which a test signal is fed with a detection device (10) into the energy supply network (12), wherein the test signal has a frequency which differs from the network frequency of the energy supply network (12), and the presence of a high-impedance ground fault is inferred on the basis of a measuring signal produced by the test signal. In order to enable a reliable detection, with low equipment costs, of high-impedance ground faults in energy supply networks with a grounded neutral point, it is proposed that a three-phase test signal is fed into the phase conductors of the energy supply network (12) as a test signal, a measuring signal which indicates the displacement voltage of the test signal is generated with the detection device (10), the displacement voltage is compared with a threshold value using a test device (15) of the detection device (10), and the presence of a high-impedance ground fault is detected if the displacement voltage exceeds the threshold value. The invention also relates to a correspondingly designed detection device (10).
Patent CA-3023239-A1 (CA)
Title: Methods of treating acute myeloid leukemia and multiple myeloma using natural killer cells
Inventor: FISCHKOFF STEVEN ALAN
IPC: C12N5/0783
Filed: 2017-05-05
Abstract: Provided herein are methods of treating acute myeloid leukemia (AML) and multiple myeloma (MM) by administering an effective amount of a cell population comprising natural killer cells, wherein the cell population comprising natural killer cells is produced by a three- stage method comprising culturing a population of hematopoietic stem or progenitor cells in media comprising stem cell mobilizing factors, e.g., three-stage methods of producing NK cells in media comprising stem cell mobilizing factors starting with hematopoietic stem or progenitor cells from cells of the placenta, for example, from placental perfusate (e.g., human placental perfusate) or other tissues, for example, umbilical cord blood or peripheral blood. Further provided herein are methods of using the NK cells produced by the three-stage methods provided herein to suppress the proliferation of acute myeloid leukemia cells. In certain embodiments, the NK cells produced by the three-stage methods described herein are used in combination with IL- 2.
Patent CA-3024319-A1 (CA)
Inventor: PATIL ABHISHEK PRAMOD
IPC: H04W48/16
Filed: 2017-06-13
Abstract: Methods, systems, and devices for wireless communications are described, including identifying a first attribute value associated with a first access point; receiving a second attribute value; and determining that the first attribute value associated with the first access point is the same as the received second attribute value. An attribute value may be an n-bit value, where n is an integer. The n-bit value may identify a BSS color. The n-bit value may, additionally or alternatively, indicate other BSS color information such as a BSSID, ESSID, SSID, or a combination thereof. It is helpful when devices detect BSS attribute value (e.g., BSS color, BSSID, MAC address, ESSID) overlap and notify other associated devices (e.g., STAs, APs) of this overlap so that a device may cease using an attribute value for power save or channel access decisions, and facilitate attribute value adjustment and correction to eliminate a BSS collision.
Patent CA-3024624-A1 (CA)
Title: Polynucleotides encoding porphobilinogen deaminase for the treatment of acute intermittent porphyria
Inventor: MARTINI PAOLO
IPC: C12N9/10
Filed: 2017-05-18
Abstract: The invention relates to mRNA therapy for the treatment of Acute Intermittent Porphyria (AIP). mRNAs for use in the invention, when administered in vivo, encode human porphobilinogen deaminase (PBGD), isoforms thereof, functional fragments thereof, and fusion proteins comprising PBGD. mRNAs of the invention are preferably encapsulated in lipid nanoparticles (LNPs) to affect efficient delivery to cells and/or tissues in subjects, when administered thereto. mRNA therapies of the invention increase and/or restore deficient levels of PBGD expression and/or activity in subjects. mRNA therapies of the invention further decrease levels of toxic metabolites associated with deficient PBGD activity in subjects, namely porphobilinogen and aminolevulinate (PBG and ALA).
Patent CA-3026017-A1 (CA)
Inventor: LUMMERSTORFER THOMAS
IPC: C08L23/12
Filed: 2017-06-27
Abstract: La présente invention concerne un nouveau composite comprenant une fibre à base de cellulose et une fibre à base de polymère ainsi que des articles moulés fabriqués à partir dudit composite.
Patent CA-3026396-A1 (CA)
Title: Traitement d'une tumeur maligne hematologique avec le 2-(4-chlorophenyl)-n-((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)methyl)-2,2-difluoroacetamide
Inventor: CARRANCIO SORAYA
IPC: A61P35/02
Filed: 2017-06-05
Abstract: L'invention concerne des méthodes de traitement, de prévention, de prise en charge et/ou d'atténuation d'une leucémie ou d'un syndrome myélodysplasique consistant à administrer à un patient le 2-(4-chlorophényl)-N-((2-(2,6-dioxopipéridin-3-yl))-1-oxoisoindolin-5-yl)méthyl)-2,2-difluoroacétamide ou un stéréo-isomère ou un mélange de stéréoisomères, un isotopologue, un sel, un tautomère, un solvate, un hydrate, un co-cristal, un clathrate ou un polymorphe pharmaceutiquement acceptables de celui-ci.
Patent CA-3028254-A1 (CA)
Inventor: SARDO ALBERTO
IPC: A61L9/14
Filed: 2017-06-20
Abstract: The method for treating the atmosphere in a storage space (3) for vegetable products (5) having a volume of more than 200 m3 comprises at least one step in which the atmosphere is brought into contact with a liquid flow by having the atmosphere flow through a packing.
Patent CA-3029195-A1 (CA)
Title: Systeme de convertisseur a grande puissance haute frequence
Inventor: JI CHAO
IPC: H05B6/68
Filed: 2017-06-29
Abstract: L'invention concerne un système de convertisseur à grande puissance haute fréquence comprenant : une pluralité de circuits oscillants finaux résonnants disposés en parallèle, une pluralité de transformateurs, chaque transformateur présentant un enroulement primaire unique et une pluralité d'enroulements secondaires, et un dispositif électronique à vide, la sortie de chaque circuit oscillant final résonnant étant appliquée à un transformateur différent respectif et les sorties des transformateurs étant conçues pour commander le dispositif électronique à vide.
Patent CA-3030165-A1 (CA)
Inventor: COWIE JACK B
IPC: G01N33/564
Filed: 2017-07-18
Abstract: The present invention provides biomarkers for efficient and accurate characterization of mast cell activity-associated diseases, disorders and/or conditions. In particular, the present invention provides biomarkers expressed in mast cell activity-associated diseases, disorders and/or conditions. Those biomarkers, used alone or in combination, may permit more accurate robust characterization of mast cell activity-associated diseases, disorders and/or conditions, resulting in more precise determination of their diagnosis and treatment, and in particular, prediction of the occurrence of MS relapse.