baber/WOPTO huggingface dataset:
Patent NZ-322910-A (NZ)
Title: Tumour vaccine containing tumour cells, some with MHC-I-haplotype on cell surface to trigger immune response, and preparation of vaccine thereof
Inventor: SCHMIDT WALTER
IPC: A61K38/19
Filed: 1996-11-21
Abstract: A tumour vaccine is claimed containing tumour cells which themselves present peptides derived from tumour antigens in an HLA content and at least a portion of which have at least one MHC-I-haplotype of the patient on the cell surface, and which have been charged with one or more peptides as defined in the specification in such way that the tumour cells are recognised as foreign by the immune system of the patient in the context of the peptides and trigger a cellular immune response. Charging takes place in the presence of a polycation such as polylysine.
Patent NZ-330572-A (NZ)
Title: A nontoxic biodegradable biological adhesive based on macromolecular polyaldehyde and a collagen based component for surgical and therapeutic use
Inventor: TARDY MICHEL
IPC: A61L24/04
Filed: 1997-10-07
Abstract: The invention concerns a biologically compatible, biologically non-absorbable and non-toxic adhesive composition, for surgical and/or therapeutic use in particular for bonding together biological tissues or with an implanted biological material, characterised in that it contains at least one biodegradable macromolecular polyaldehyde of natural origin, in an aqueous solution such as oxidised starch or a polyaldehyde with similar properties of stability. This composition can further contain one collagenic constituent selected among: collagen having partially lost its helical structure, non-hydrolysed, consisting mostly of alpha chains, rendered soluble in an aqueous medium; and native collagen in a concentration less than 5 %. The invention also concerns a method for bonding biological tissues together or to an implanted biological material using this adhesive composition. The invention is useful for preventing post-operative adhesions.
Patent NZ-332174-A (NZ)
Title: Reactor and method for solid peptide synthesis
Inventor: STEPANIUK NICHOLAS
IPC: C40B40/10
Filed: 1998-02-10
Abstract: PCT No. PCT/US98/02634 Sec. 371 Date Mar. 9, 1999 Sec. 102(e) Date Mar. 9, 1999 PCT Filed Feb. 10, 1998 PCT Pub. No. WO98/34633 PCT Pub. Date Aug. 13, 1998A solid phase peptide synthesis reactor system and method of operating the reactor are provided. The reactor system includes a basket rotatable about an axis within a housing and a receiver which delivers fluid to, and collects fluid from, the housing. The basket has a perforate side wall against which a resin cake for the peptide synthesis is formed. The reactor and receiver form a loop or circuit through which solutions are circulated. The circulation of the solutions prevents the reactor from flooding so that the basket will not be submerged in solution and allows for the use of less liquid. Thus greater amino acid concentrations may be used. The method includes forming a resin cake of uniform depth on the wall of the spinning basket and spraying the solutions against the resin cake while spinning the basket. The solutions will pass through the resin cake and drain to the receiver to be circulated or recycled through the system or discharged from the system. Before a subsequent solution is introduced into the reactor system, the prior solution is purged from the system to help control exposure time of the peptide to the solutions.
Patent NZ-335958-A (NZ)
Title: Lightning retardant cable
Inventor: GASQUE SAMUEL N
IPC: H01B9/02
Filed: 1997-02-28
Abstract: A lightning retardant cable 26 includes at least one internal conductor 44 which may be a power conductor or a signal conductor.  A choke conductor 56 is wound about internal conductor 44 in the shape of a spiral.  Choke conductor 56 is not in direct contact with internal conductor 44.  If lightning strikes near the cable or a device which is attached to the cable, such as an antenna, the choke conductor presents a high impedance to the current caused by lightning and will prevent the lightning current from flowing down the choke conductor, thus entering the internal conductor, thereby preventing damage to the internal conductor and any associated electronic equipment.  A shield 58 is also spiraled wound about internal conductor 44.  Spiraled shield 58 is not in direct contact with internal conductor 44.
Patent NZ-500862-A (NZ)
Title: Ceiling panel support system including parallel main runners supporting tiles and interconnected by transverse struts obscured by the tiles
Inventor: CRICK ANDREW
IPC: E04B9/28
Filed: 1999-11-08
Abstract: Tiles 13 are located between main runners 11 (having ledges 21) and between transverse struts 12 which may be composite as shown.  Grooves in adjacent tiles accommodate feet of struts 12 so that struts 12 are obscured from view after installation.
Patent NZ-501380-A (NZ)
Title: A method and system for distributed caching, prefetching and replication
Inventor: YATES DAVID J
IPC: G06F17/30
Filed: 1998-05-15
Abstract: A technique is disclosed for automatic, transparent, distributed, scalable and robust caching, "prefetching", and replication in a computer network that request messages for a particular document follow paths from the clients to a home server that form a routing graph. Client request messages are routed up the graph towards the home server as would normally occur in the absence of caching. However, cache servers are located along the route, and may intercept requests if they can be serviced. In order to be able to service requests in this manner without departing from standard network protocols, the cache server needs to be able to insert a packet filter into the router associated with it, and needs also to proxy for the homer server from the perspective of the client. Cache servers may cooperate to service client requests by caching and discarding documents based on its local load, the load on its neighboring caches, attached communication path load, and on document popularity. The cache servers can also implement security schemes and other document transformation features.
Patent NZ-502882-A (NZ)
Title: Lyxofuranosyl benzimidazoles as antiviral agents
Inventor: TOWNSEND LEROY B
IPC: A61K31/7056
Filed: 1998-07-29
Abstract: A D- or L-lyxofuranosyl benzimidazole compound selected from the given formulae wherein; R2, R4, R5, R6, and R7 are independently the same or different and independently selected from -H, -F, -Cl, -Br, -I, -NO2, -N(R8)2, -OR8, -SR12, and -CF3, wherein R8 is independently -H or an alkyl group having 1-6 carbon atoms and wherein R12 is independently -H or a hydrocarbyl group having 1-10 carbon atoms; and R9, R1O and R" are independently the same or different and are H or a hydroxyl protecting group; anomeric, optical, and conformational isomers thereof; and, pharmaceutically acceptable salts and prodrug derivatives thereof with the proviso that, for beta-D and alpha-D compounds in which both R4 and R7 are H and both of R5 and R6 are Cl, R2 is not H. The compounds is useful in treating viral infection.
Patent NZ-507992-A (NZ)
Title: Dry wall building elements joined by keys and methods of construction
Inventor: RYDER GEORGE RALPH
IPC: E04B2/20
Filed: 1999-05-11
Abstract: A dry wall building system comprises courses of building blocks (36) where the building blocks are joined end to end by keys (1). Each of the blocks comprising sidewalls (37), endwalls (38) and at least one vertical cavity (39) or slot (39), at least one first channel (40) in the upper surfaces (22) of the endwalls and at least one second channel (41) in the lower surfaces (23) of the endwalls, the arrangement and construction being such that when blocks are laid one upon another the channels and at least one cavity or slot of the blocks can be aligned to provide an internal network of horizontal and vertical infill passages (42, 43) which can be filled with a settable material to seal joints between the blocks and to provide load bearing support between respective courses of blocks. A method of manufacturing blocks is also disclosed.
Patent NZ-508664-A (NZ)
Title: Roadway deicing with pressurised gas as source of energy
Inventor: THOMPSON JEFFREY M
IPC: E01H10/00
Filed: 2000-12-06
Abstract: Disclosed is apparatus to dispense a de-icing solution by pressurized gas onto a roadway. This is stated to be useful where electrical power for pumping is not available. Typically, storage tank 12 contains de-icing fluid, typically brine. Pressure tank 14 is connected via piping and solenoid valve V1 to tank 12. Nitrogen tank 16 is connected via regulator 28 and  solenoid valve V3 to pressure tank 14, which supplies nozzles 18 with brine. Control system details are disclosed.
Patent NZ-513135-A (NZ)
Title: The preparation and use of radium-223 to target calcified tissues for pain palliation, bone cancer therapy, and bone surface conditioning
Inventor: LARSEN ROY H
IPC: A61K51/00
Filed: 1999-12-17
Abstract: Use of radium-223 to produce a pharmaceutically active preparation to treat diseased bone and bone surfaces, such as primary or metastatic bone cancer; or for therapy and/or palliation related to non-malignant and malignant disease affecting bones and/or soft tissues such as prostate cancer, breast cancer, kidney and urinary cancer, primary bone cancer, lung cancer or multiple myeloma.
Patent NZ-516507-A (NZ)
Title: Growth hormone formulations that are resistant to crystallisation
Inventor: SIEBOLD BERNHARD
IPC: A61K47/10
Filed: 2000-07-11
Abstract: A multi-dosage, storage stable liquid human growth hormone formulation which is resistant to crystallization, consisting essentially of growth hormone in isotonic phosphate buffered solution, a preservative and a non-ionic surfactant, wherein isotonicity of the phosphate buffered solution is provided by a neutral salt, a monosaccharide, a disaccharide or a sugar alcohol, the formulation having pH in the range of 6.15 to 6.5.
Patent NZ-516722-A (NZ)
IPC: C12Q1/68
Filed: 2000-07-10
Abstract: The present invention is directed to methods and compositions for DNA subcloning using bacterial recombinase-mediated homologous recombination. The invention relates to methods for cloning, compositions comprising polynucleotides usefall as cloning vectors, cells comprising such polynucleotide compositions, and kits useful for cloning mediated by bacterial recombinases, such as RecE/T and Redalpha/beta.
Patent NZ-518356-A (NZ)
Title: Two part chemical anchoring adhesive in the form of a rope for use in sealing boreholes
Inventor: ERNST RICHARD J
IPC: C09J4/06
Filed: 2001-07-23
Abstract: A rope of chemical anchoring adhesive comprises a first part comprising a resin and a second part comprising a curing agent.  The first and second parts are joined along an interface which extends a length of the rope with the first and second parts each having a viscosity of 5 million to 50 million centipoises.
Patent NZ-523311-A (NZ)
Title: Novel gamma crystalline form of perindopril tert-butylamine salt, preparation method, and pharmaceutical compositions containing same
Inventor: PFEIFFER BRUNO
IPC: C07D209/42
Filed: 2001-07-06
Abstract: A g crystalline form of a compound of formula (I) characterised by its X-ray diffraction pattern on powder and a process for the preparation of this compound is disclosed. The g crystalline form of a compound of formula (I) is suitable for treating cardiovascular diseases.
Patent NZ-525313-A (NZ)
Title: Improvements in and relating to cams
Inventor: REID PETER JOHN KENNETH
IPC: F16H53/04
Filed: 2003-04-16
Abstract: A cam system (1) including at least two cam structures, a cam follower capable of following a preferred profile effected by the configuration of at least one of the cam structures, and a movable cam shaft, the at least two cam structures comprising at least one central cam structure (2) and at least one side cam structure (3, 3a), the central cam structure (2) being adapted (at 9) to receive the cam shaft and move therewith, said central cam structure (2) further adapted to receive the at least one side cam structure (3, 3a), the side cam structure (3, 3a) being adapted to be positionally varied with respect to the central cam structure (2) thereby effecting a change in the overall profile followed by the cam follower during movement of the cam shaft and the cam structure(s) related thereto, the cam system (1) characterized by the change in profile effected by the positional configuration of the side cam structure (3, 3a) effecting variable translational motion to the cam follower during movement of the cam shaft and cam structures associated therewith and effecting in turn a variation in speed of operation of a preferred mechanical requirement.
Patent NZ-526891-A (NZ)
Title: The use of food and drink as a delivery system for phytase in humans
Inventor: BEUDEKER ROBERT FRANCISCUS
IPC: A23L29/00
Filed: 2002-01-09
Abstract: Use of phytase to increase the uptake of minerals, and in particular calcium, in a diet for humans is disclosed, wherein the food or drink containing pasteurized milk is used as the delivery system for phytase for human consumption.
Patent NZ-531346-A (NZ)
Title: Medicinal compositions containing angiotensin II receptor antagonist
Inventor: SADA TOSHIO
IPC: A61P9/10
Filed: 2002-08-27
Abstract: A pharmaceutical composition comprising as active ingredients an angiotensin II receptor antagonist and an ACAT inhibitor is disclosed, wherein the composition is in a form suitable for separate or sequential administration of an angiotensin II receptor antagonist and an ACAT inhibitor as the active ingredients. These pharmaceutical compositions are suitable for the prevention or treatment of ischemic heart disease, ischemic brain disease or peripheral circulatory failure in a warm blooded animal.
Patent NZ-532405-A (NZ)
Title: Treatment of acute myeloid leukemia with indolinone compounds
Inventor: O'FARRELL ANN-MARIE
IPC: C07D473/00
Filed: 2002-10-28
Abstract: Disclosed is the use of compounds of the formula (I), wherein; X is O or S; j is 0-1; p is 0-3; q is 0-2; r is 0-3; Z is -OH; -Oalkyi; -NR3R4, where R3 and R4 are independently selected from the group consisting of hydrogen, alkyl, aryl, heteroaryl, cycloalkyl, and heterocyclic, or R3 and R4 may combine with N to form a ring where the ring atoms are selected from the group consisting of CH2 N, O and S or formula (II); wherein Y is independently CH2, O, N or S, Q is C or N; n is independently 0-4; and m is 0-3 or a salt thereof, for the manufacture of a medicament for the treatment of acute myeloid leukemia in a patient, wherein the patient is FLT-3-ITD positive.
Patent NZ-533386-A (NZ)
Title: Disposable paint cup attachment system for gravity-feed paint sprayer
Inventor: GOSIS ANATOLY
IPC: B05B7/24
Filed: 2004-06-08
Abstract: A fluid supply cup comprises a flexible liner integral with a container having an opening and a vent. A novel method of manufacturing a lined container comprises the steps of molding a container having a vented thick-walled portion and an integral flexible thin-walled liner, and folding the thin-walled liner into the thick-walled portion. Additionally, a method of applying a fluid comprises the steps of providing a flexible liner integral with a container having an opening and a vent, loading fluid into the liner, engaging the container with a fluid applicator, flowing the fluid out of the liner into the fluid applicator, collapsing the liner, and flowing the fluid of the fluid applicator.
Patent NZ-536147-A (NZ)
Title: Method of preparation of high quality soy-containing cheese products
Inventor: AKASHE AHMAD
IPC: A23L11/30
Filed: 2004-10-26
Abstract: A soy-containing cheese product comprises a cheese base composition and a deflavoured soy protein material. The deflavoured soy protein material is prepared by a method comprising: (a) preparing an aqueous composition of a soy material containing soluble soy proteins, flavouring compounds, and insoluble materials; (b) solubilizing the soy proteins by adjusting the aqueous composition of (a) to a pH in the range of about 9 to about 12 and releasing the flavouring compounds; (c) passing the pH-adjusted aqueous composition of (b) adjacent to the ultrafiltration membrane having a molecular weight cutoff up to about 50,000 Daltons, while maintaining the pH in the range of about 9 to about 12, under suitable ultrafiltration conditions wherein the flavour compounds pass through the membrane, thereby deflavouring the soy protein composition and retaining substantially all of the solubilized soy proteins; (d) recovering the solubilized soy proteins retained by the ultrafiltration membrane, wherein the recovered solubilized soy proteins comprise deflavoured soy protein material; and (e) blending the deflavoured soy protein material with a natural or process dairy cheese base composition, providing a soy-containing cheese product.
Patent NZ-536415-A (NZ)
Title: Triple monoamine reuptake inhibitors for the treatment of chronic pain
Inventor: SCHEELKRUGER JORGEN
IPC: A61P1/02
Filed: 2003-05-27
Abstract: The use of the compound of the compound of the general formula (I) or a pharmaceutically acceptable addition salt thereof or the N-oxide thereof, wherein: R is hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkylalkyl or 2-hydroxyethyl; R3 is CH2-X-R', wherein X is O, S, or NR"; wherein R" is alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkylalkyl, -CO-alkyl; R4 is 3,4-methylenedioxyphenyl; or phenyl, benzyl, naphthyl, or heteroaryl, each of which may be substituted one or more times with substituents selected from the group consisting of halogen, CF3, CN, alkoxy, cycloalkoxy, alkyl, cycloalkyl, alkenyl, alkynyl, amino, nitro, heteroaryl, aryl; for the manufacture of a medicament for the treatment, prevention or alleviation of chronic pain, such as inflammatory pain, neuropathic pain, fibromyalgia, or tension-type headache.
Patent NZ-537043-A (NZ)
Title: Nitrooxyderivatives of cyclooxygenase-2 inhibitors
Inventor: DEL SOLDATO PIERO
IPC: A61P29/00
Filed: 2003-06-20
Abstract: Disclosed are compounds of formula M-T-YA-NO2, as defined in the specification, which are able to release COX-2 inhibitors and NO (nitrogen oxide) under conditions and according to the parameters set up in test 1 mentioned in the description. The test is met by compounds of formula (I) having a COX-1 inhibiting activity/ COX-2 inhibiting activity ratio expressed as IC50, greater than or equal to 5 and having a NO release that is at a concentration equal to or greater than 0.1 microM. Compounds of the type disclosed are useful for the treatment or prophylaxis of inflammatory disorders, pain, fever, cardiovascular diseases, gastrointestinal disorders, tumours, Alzheimer's disease and disorders in general resulting from elevated levels of COX-2.
Patent NZ-538629-A (NZ)
Title: Mucin-immunoglobulin fusion proteins
Inventor: HOLGERSSON JAN
IPC: A61K38/00
Filed: 2003-08-11
Abstract: A fusion polypeptide comprising a) a mucin polypeptide having a glycan repertoire including the following sequence i) Hex-HexNol-HexN-Hex-Hex ii) NeuAc-Hex-HexNol-HexN- Hex-Hex and iii) NeuGc-Hex-HexNol-HexN-Hex-Hex; and b) at least a region of an immunoglobulin polypeptide wherein the fusion polypeptide binds a Gal-alpha, 3Gal specific antibody.
Patent NZ-540486-A (NZ)
Title: Oil-less rivet system for a reclining chair mechanism
Inventor: LAPOINTE LARRY P
IPC: F16B5/04
Filed: 2003-12-22
Abstract: A rivet system of the type having a rivet pivotally coupling a first connecting link and a second connecting link, the system comprising: a metal rivet having an enlarged head portion and a shank portion having a shoulder portion adjacent to the head portion and a tenon portion, the shank portion received within apertures formed through the first and second connecting links; a thrust washer received on the tenon portion interposed between the first connecting link and the second connecting link, the thrust washer being fabricated of a low friction plastic material and having a metallic contact adapted to conduct electricity between the first and second connecting links; a spring bushing received on the shank portion having a washer portion interposed between between the first connecting link and the enlarged head portion; and a bush received within the aperture formed in the first connecting link, the bushing being fabricated of a low friction plastic material and being adapted to provide an axial thrust within the rivet system.
Patent NZ-542482-A (NZ)
Title: Novel galactooligosaccharide composition from Bifidobacterium bifidum and the preparation thereof
Inventor: GIBSON GLENN
IPC: A23C9/123
Filed: 2004-06-30
Abstract: Disclosed is a strain of Bifidobacterium bifidum that produces a galactosidase enzyme activity that converts lactose to a galactooligosaccharide mixture comprising disaccharide Gal (alpha1-6)-Gal, at least one trisaccharide selected from Gal (beta1-6)-Gal (beta1-4)-Glc, Gal (beta1-3)-Gal (beta1-4)-Glc, tetrasaccharide Gal (beta1-6)-Gal (beta1-4)-Glc, and pentasaccharide Gal (beta1-6)-Gal (beta1-6)-Gal (beta1-6)-Gal (beta1-4)-Glc where Gal represents a galactose residue and Glc represents a glucose residue. Also described is a galactooligosaccharide composition for promoting specific growth of bifidobacteria comprising, as effective constituents, a mixture comprising disaccharide Gal(alpha1-6)-Gal, from at least one trisaccharide selected from Gal (beta1-6)-Gal (beta1-4)-Glc, Gal (beta1-3)-Gal (beta1-4)-Glc, tetrasaccharide Gal (beta1-6)-Gal (beta1-4)-Glc, and pentasaccharide Gal (beta1-6)-Gal (beta1-6)-Gal (beta1-6)-Gal (beta1-4)-Glc, and compositions for improving gut health comprising the Bifidobacterium bifidum strain.
Patent NZ-545139-A (NZ)
Title: 1-[2-(2-Ethyl-2H-tetrazol-5-yl)-ethyl]-3-[5-(3-fluoro-4-methanesulfonylphenyl)-4-methyl-thiazol-2-yl]-urea
Inventor: BLOOMFIELD GRAHAM CHARLES
IPC: C07D451/04
Filed: 2004-08-27
Abstract: Disclosed is a compound which is 1-[2-(2-ethyl-2H-tetrazol-5-yl)-ethyl]-3-[5-(3-fluoro-4-methanesulfonylphenyl)-4-methyl-thiazol-2-yl]-urea, in free or salt form. The compound disclosed is a phosphatidylinositol 3-kinase inhibitor useful in the treatment of diseases associated therewith.
Patent NZ-546477-A (NZ)
Title: 4-Alkylamino-2-(heterocyclic)quinazolines and their use in cancer therapy
Inventor: SUTHERLAND HAMISH SCOTT
Filed: 2006-04-07
Abstract: Disclosed are compounds of formula I, processes for their preparation and intermediates for use therein. The compounds display favourable in vivo and in vitro activity against selected cancers.
Patent NZ-551978-A (NZ)
Title: Mitre box with plural profile locating means
Inventor: DELLAR CAMERON
Filed: 2006-12-12
Abstract: A mitre box is disclosed for guiding the cutting of one or more profiles, and includes a base having an elongate axis and a plurality of profile locating means spaced transversely across the base for locating two or more different profiles parallel to the axis, and cutting guide means defining at least one cutting plane which intersects with the axis at a predetermined angle.
Patent NZ-568807-A (NZ)
Title: Triazolopyridazines as tyrosine kinase modulators
Inventor: LU TIANBAO
IPC: A61K31/5025
Filed: 2006-12-18
Abstract: Disclosed herein are triazolopyridazine compounds of Formula (I), wherein the substituents are as defined in the specification, the use of such compounds as protein tyrosine kinase modulators, particularly inhibitors of c-Met, the use of such compounds to reduce or inhibit kinase activity of c-Met (a proto-oncogene that encodes a protein known as hepatocyte growth factor receptor (HGFR))in a cell or a subject, and modulation of c-Met expression in a cell or subject and the use of such compounds for preventing or treating in a subject a cell proliferative disorder and/or disorders related to c-Met. Also disclosed are pharmaceutical compositions comprising the compounds of the present invention, methods for treating conditions such as cancers and other cell proliferative disorders as well as processes for producing compounds of formula (I).