baber/WOPTO huggingface dataset:
Patent CA-2310629-A1 (CA)
Title: Imidazole derivatives having an inhibitory activity for farnesyl transferase and process for preparation thereof
Inventor: CHOI TAE SAENG
IPC: A61K31/425
Filed: 1998-11-25
Abstract: The present invention relates to a novel imidazole derivative represented by formula (1) which shows an inhibitory activity against farnesyl transferase or pharmaceutically acceptable salts or isomers thereof, in which A, n1 and Y are defined in the specification; to a process for preparation of the compound of formula (1); to intermediates which are used in the preparation of the compound of formula (1); and to a pharmaceutical composition comprising the compound of formula (1) as an active ingredient.
Patent CA-2314074-A1 (CA)
Title: Compositions adhesives a base de melanges de metallocene greffe catalyse et de copolymeres polaires d'ethylene
Inventor: LEE I-HWA
IPC: C08L51/06
Filed: 1999-01-27
Abstract: Ces compositions adhésives à base de polyéthylène, qui contiennent de 5 à 35 % en poids d'un polyéthylène métallocène greffé à l'acide, sont dotées d'une résistance au pelage supérieure à celle de compositions comparable contenant un polyéthylène non métallocène greffé à l'acide et un polyéthylène vinyl-acétate (EVA) ou un polyéthylène méthacrylate (EMA). Les compositions dans lesquelles le constituant polyéthylène métallocène greffé à l'acide est un polyéthylène métallocène doté d'un indice de fluage inférieur à 6,53 et d'un poids moléculaire en poids/poids moléculaire en nombre (Mw/Mn) inférieur à l'indice de fluage moins 4,63, s'avèrent être de compositions dont les qualités d'adhérence sont aussi élevées que celles de compositions à base de résines métallocènes dont les valeurs excèdent ces paramètres.
Patent CA-2314229-A1 (CA)
Title: Polymeric composition for sealing and shielding animal skin
Inventor: SHAH KISHORE R
IPC: A61L24/04
Filed: 1998-12-11
Abstract: A two part, polymerizable, skin sealant or shield which cures in situ to form a custom made, solid, shaped, skin friendly barrier which absorbs aqueous fluids without disintegrating.
Patent CA-2314887-A1 (CA)
Title: An animal related apparatus
Inventor: ERIKSSON JAN
IPC: A01J7/00
Filed: 1998-12-18
Abstract: An animal related apparatus comprises a robot for performing an animal related operation, said robot being associated with a control means, and at least one animal related device associated with said control means, said robot being provided with a robot arm adapted to move said animal related device towards an animal. According to the invention, a registering means is provided for registering a cumulative running value, said control means being adapted to generate a signal when a predetermined threshold value has been reached.
Patent CA-2319503-A1 (CA)
Title: Leak-proof cup with flow control
Inventor: MANGANIELLO FRANCIS X
IPC: A47G19/22
Filed: 1999-02-04
Abstract: A drinking cup assembly (10) including a cup (12) having an open end and a cap (14) adapted to close the open end. The cap (14) includes a drinking spout (16) and an air vent (18), each having mating surfaces adjacent or incorporated therein. A flow control valve (20) has two stacks (24) adapted to engage the mating surfaces of the drinking spout (16) and air vent (18). Each of the two stacks has a concave valve face (30) at a top portion thereof.
Patent CA-2320010-A1 (CA)
Inventor: PERDUE JERRY THOMAS
IPC: H01R43/10
Filed: 2000-09-18
Abstract: The present invention advantageously provides a cost effective flat rotor for a pancake type slip ring. A flat copper coil sheet is stamped into a corrugated shape having concentric V-ring grooves. The corrugated stamped copper foil sheet is bonded using a bonding agent to a dielectric layer. Multiple concentric V-grooves are formed by separating the grooves, for example, by machining the grooves at an apex thereof in order to form separate electrical circuits. A corresponding plurality of holes extend through each concentric ring and through the dielectric layer from the first side through the second side. A conductive material is placed in each of the plurality of holes to electrically connect each concentric ring to the second side.
Patent CA-2320718-A1 (CA)
Inventor: PACKER LESTER
IPC: A61K8/00
Filed: 1999-03-05
Abstract: L'invention concerne un composé représenté par la formule (I). Dans cette formule, R?1¿ et R?2¿ représentent indépendamment un groupe méthylène, éthylène ou C¿3-16? alkylène ramifié ou non, alkénylène ou alkynylène, substitué ou non par un ou plusieurs groupes halogène, hydroxyle ou amine, dans lesquels le groupe C¿3-16? alkylène ramifié ou non, alkénylène, ou alkynylène d'un atome de carbone de l'alkylène interne peut être remplacé par un atome d'oxygène dans le squelette carboné; R?3¿ et R?4¿ (i) représentent indépendamment (a) hydrogène; (b) un groupe méthyle, éthyle, vinyle ou C¿3-16? alkyle ramifié ou non, alkényle ou alkynyle substitué ou non, par un ou plusieurs groupes halogène, hydroxyle ou amine, dans lesquels un groupe C¿3-16? alkyle ramifié ou non, alkényle, ou alkynyle d'un atome de carbone de l'alkylène interne peut être remplacé par un atome d'oxygène dans le squelette carboné; (c) un groupe cycloalkyle, alkylcycloalkyle, alkénylcycloalkyle ou alkynylcycloalkyle possédant 5 à 16 atomes de carbone, substitué ou non par un ou plusieurs groupes halogène, hydroxyle ou amine ou (d) un groupe aryle, alkaryle, aralkyle, alkénylaryle, aralkényle, alkynylaryle ou aralkynyle possédant 6 à 16 atomes de carbone substitué ou non par un ou plusieurs groupes halogène, hydroxyle ou amine, ou (ii) conjointement avec la forme d'atome d'azote un amine aromatique ou cyclique, substitué ou non par un ou plusieurs groupes alkyle, alkényle, alkynyle, halogène, hydroxyle ou amine; X représente O, S, -NH- ou -NR5-, et R?5¿ représente méthyle, éthyle, ou C3-16 alkyle ramifié ou non. L'invention concerne également un sel pharmaceutiquement acceptable de ce composé, le composé étant en équilibre à un pH physiologique avec une forme protonée. L'invention concerne également des procédés de fabrication de ces composés, des compositions comprenant ces composés et des procédés de traitement d'états impliquant des espèces d'oxygène réactives.
Patent CA-2326475-A1 (CA)
Title: Un dispositif amovible de traction adapte pour tout vehicule motorise
Inventor: LABBE GUY
IPC: B60C27/06
Filed: 2000-11-29
Abstract: La présente invention se rapporte à un dispositif amovible de traction de forme allongée, constitué de chaînes installées sur la bande de roulement des roues motrices, et des bras de serrage ajustables généralement plats mun is de boulons permettent aux pattes piquées de s'ajuster aux flancs des pneus.< /SDOAB>
Patent CA-2328358-A1 (CA)
Inventor: SINZAWA KOUICHI
IPC: B60Q3/02
Filed: 2000-12-14
Abstract: An automotive lamp unit includes a bus bar unit forming a circuit with a plurality of bus bars connected with each other via a bridge portion, the bus bar unit including terminals, for connection to switches and a power source, and a supporting member for supporting a lamp, the circuit serving to switch on the lamp, and a resin base member provided with the bus bar unit mounted thereon at a predetermined position, and a small hole formed in the resin base member at a position thereof associated with the bridge portion. The plurality of bus bars are separated from each other at the bridge portion which is disposed in the small hole.
Patent CA-2330225-A1 (CA)
Inventor: SCHWARTZ DAVID
IPC: A61K39/39
Filed: 1999-06-04
Abstract: La présente invention concerne des compositions oligonucléotidiques immunostimulatrices, Ces olignucléotides comprennent une séquence d'hexanucléotides immunostimulateurs renfermant une cytosine modifiée. Ces oligonucléotides peuvent être administrés conjointement avec un peptide ou un antigène immunostimulateur. L'invention s'applique également à des méthodes qui permettent de moduler une réponse immunitaire par administration d'un oligonucléotide renfermant une séquence immunostimulatrice modifiée.
Patent CA-2331741-A1 (CA)
Title: Methods for using dehydrogenases in baking
Inventor: WAGNER PETER
IPC: A21D8/04
Filed: 1999-05-13
Abstract: The present invention relates to methods for preparing a dough, comprising incorporating into the dough a composition comprising an effective amount of one or more dehydrogenases which improve one or more properties of the dough or a baked product obtained from the dough. The present invention also relates to methods for preparing a baked product. The present invention also relates to compositions comprising an effective amount of one or more dehydrogenases for improving one or more properties of a dough and/or a baked product obtained from the dough. The present invention further relates to doughs or baked products and to pre-mixes for a dough.
Patent CA-2332552-A1 (CA)
Inventor: DUBOIS JEAN-CLAUDE
IPC: G01V1/047
Filed: 2001-01-31
Abstract: Vibrateur comportant un générateur de vibrations unique couplé avec le milie u par un élément de couplage et des moyens de commande du générateur adaptés à lui appliquer, à chaque émission, un signal pilote unique obtenu par la combinaison d'au moins deux signaux de fréquences différentes fixes ou de préférence variable s à l'intérieur de bandes de fréquence au moins partiellement disjointes, et des  moyens de transmission élastique non linéaire adaptés à engendrer dans le milieu des vibrations à une fréquence dépendant de la différence des fréquences des deux signaux vibratoires. La méthode d'exploration comporte une mise en oeuvre du vibrateur pour émett re des vibrations à très basse fréquence dans le milieu, la réception par des capteurs des ondes renvoyées par le milieu en réponse aux vibrations émises et leur enregistrement, et la sélection par corrélation des signaux vibratoires avec un signal synthétique  dont la fréquence est en relation avec la différence des fréquences des signaux constituant le signal pilote.  Applications dans le domaine de la prospection sismique par exemple.</S DOAB>
Patent CA-2333862-A1 (CA)
Inventor: JOHNSON BERTHULD T
IPC: A61M21/00
Filed: 2001-02-05
Abstract: An eye exercise and therapy device for use by a person while lying on a horizontal support includes a generally spherical weighted ball with a string attached to the weight member by which the weight member maybe suspended from a support such as the ceiling so as to hang from the support for movement in a circular or elliptical movement below the support and above the face of the lying person. The ball is covered by a luminous coating by which it glows in a darkened room for viewing of the path by the person lying underneath the path. The ball has a circumferential groove for receiving the string when stored.
Patent CA-2334578-A1 (CA)
Inventor: MATHIASSON MIKAEL
IPC: B27N3/14
Filed: 1999-06-03
Abstract: Method for continuous forming of a fiber mat for manufacturing fiberboard according to the dry method, including metering fiber material and depositin g the material on a surface of a moving transport means and forming the mat by  means of adjustable rotating forming rolls (1). The forming rolls (1) are working in the deposited material whereby the upper surface of the mat is defined by the last forming roll (5). A bulb (4) of material is formed in front of the last forming roll (5) and the size of the bulb is indicated and  used for control of the vertical position of the last forming roll (5).</SDO AB>
Patent CA-2335978-A1 (CA)
Title: Compounds of unstable dipeptidyl peptidase iv inhibitors
Inventor: GLUND KONRAD
IPC: A61P25/00
Filed: 1999-06-24
Abstract: The invention relates to compounds of unstable inhibitors of dipeptidyl peptidase IV (DP IV) which comprise general formula A-B-C, whereby A  represents an amino acid, B represents the chemical bond between A and C or an amino acid, and C represents an unstable inhibitor of DP IV. Such compounds are used for treating altered glucose tolerance, glucosuria, hyperlipidemia, metabolic acidoses, diabetes mellitus, diabetic neuropathy, nephropathy, and secondary diseases in mammals caused by diabetes mellitus.
Patent CA-2336129-A1 (CA)
Inventor: HANSEN OLAF
IPC: A01N43/84
Filed: 1999-06-11
Abstract: The invention relates to the use of cyclical depsipeptides of formula (I) for combating ectoparasites. X1, X2, X3 and X4 mean oxygen or sulphur independently of each other and when R1 and R2 both mean hydrogen, at least one of the radicals X1, X2, X3 and X4 represents sulphur.
Patent CA-2336193-A1 (CA)
Title: Strain sensor with optical fibre bragg gratings
Inventor: KENNY ROBERT PATRICK
IPC: G02B6/00
Filed: 1999-11-11
Abstract: Strain sensors, and in particular strain rosettes, are described and claimed, in which the strain sensing elements are fibre Bragg gratings. Strain sensors in accordance with the described invention comprise first and second fibre Bragg gratings, and a length of optical fibre connecting the gratings in series, each grating being substantially straight and the two gratings being non-parallel and having different nominal Bragg wavelengths, the connecting length of optical fibre having a bend, characterised in that a portion of the connecting length is tapered, the tapered portion including an elongate waist portion having a reduced cross sectional area and said bend is formed in the waist portion.
Patent CA-2336263-A1 (CA)
Title: Kvlqt1 - a long qt syndrome
Inventor: SPLAWSKI IGOR
IPC: C12Q1/68
Filed: 1999-05-12
Abstract: The genomic structure including the sequence of the intron/exon junctions is  disclosed for KVLQT1 and KCNE1 which are genes associated with long QT syndrome. Additional sequence data for the two genes are also disclosed. Als o disclosed are newly found mutations in KVLQT1 which result in long QT syndrome. The intron/exon junction sequence data allow for the design of primer pairs to amplify and sequence across all of the exons of the two gene s. This can be used to screen persons for the presence of mutations which cause  long QT syndrome. Assays can be performed to screen persons for the presence  of mutations in either the DNA or proteins. The DNA and proteins may also be  used in assays to screen for drugs which will be useful in treating or preventing the occurrence of long QT syndrome.
Patent CA-2337544-A1 (CA)
Title: Methods for making optically active 3-aminopyrrolidine-2,5-dione derivative and optically active 3-aminopyrrolidine derivative
Inventor: ONO TAKAE
IPC: C07D207/416
Filed: 2001-02-19
Abstract: A method for making an optically active 3- aminopyrrolidine-2,5-dione derivative represented by the formula (3) includes cyclizing an optically active asparagine ester derivative represented by the formula (1) or (2), or an acid salt thereof. A method for making an optically active 3-aminopyrrolidine derivative represented by the formula (9) includes reducing the optically active 3- aminopyrrolidine-2,5-dione derivative represented by the formula (3). A method f'or making an optically active 3- aminopyrrolidine derivative includes hydrogenolyzing the optically active 3-aminopyrrolidine derivative represented by the formula (9).
Patent CA-2338344-A1 (CA)
Inventor: GERSON STANTON L
IPC: C12N5/0789
Filed: 1999-05-28
Abstract: L'invention porte sur des cellules progénitrices hématopoïétiques obtenues par génie génétique et qui comportent des gènes, notamment l'expression de protéines physiologiquement et pharmacologiquement actives. Les cellules progénitrices hématopoïétiques sont transduites en présence de cellules souches mésenchymateuses humaines qui améliorent l'efficacité de la transduction.
Patent CA-2340764-A1 (CA)
Inventor: MCDANIEL JACK A
IPC: A01G1/04
Filed: 1999-08-06
Abstract: A mushroom bed having a compost layer and a casing layer. The casing layer comprises casing spawn comprising a mixture of: (a) at least one proteinaceous ingredient in an amount to provide at least 3.5 %  nitrogen on a dry weight basis; (b) 2 to 30 wt.% based on dry weight of paper pellets; (c) 5 to 60 wt.% based on dry weight of at least one praticulate material; (d) a buffer in an amount effective to provide a pH of about 6 to 7.8; and (e) water; and colonized with mushroom mycelium.
Patent CA-2341007-A1 (CA)
Inventor: KOMOR JOSEPH A
IPC: D06M13/402
Filed: 1999-08-19
Abstract: L'invention concerne des dérivés amphotères de polyamines aliphatiques, du type diéthylènetriamine ou triéthylènetriamine, ayant réagi avec des acides gras, des esters ou des triglycérides à chaîne longue d'origines naturelles ou synthétiques diverses, qui sont efficaces pour le ramollissement/la modification de texture sur des substrats comme le papier, les textiles, la surface de la peau humaine et les tresses de cheveux, mais aussi dans les applications de l'industrie transformatrice des métaux et la lubrification. On fait d'abord réagir les polyamines avec des acides gras, des esters ou des triglycérides de différentes origines animales, végétales ou synthétiques à répartition moléculaire allant de l'acide butyrique à l'acide érucique (par exemple, matière grasse du lait, huile de soja, huile de colza) pour obtenir des diamides ou des imidazolines. Ensuite, on engage une réaction de ces produits avec des acides carboxyliques non saturés ou halogénés, des composés époxy carboxylés ou des anhydrides acides (par exemple, acide acrylique, acide itaconique, acide chloroacétique, anhydride maléique, octadécénylanhydride), de manière à constituer différentes structures amphotères.
Patent CA-2341556-A1 (CA)
Inventor: MORENO-GINER MARIA ANTONIETA
IPC: E06C7/08
Filed: 2000-01-07
Abstract: A foldable step steel (10) includes a frame 12 having front and rear legs (14, 16) and top, middle, and bottom steps (34, 36, 38). A central step link (40) is coupled to the rear portion of each step (34, 36, 38) to support the steps when step stool (10) is unfolded and to control pivoting movement of the steps relative to front leg (14) during folding of step stool (10). A releasable latch (22) is coupled to a rear portion of top step (34) and configured to engage an upper cross strut (180) included in rear leg (16) to retain step stool (10) in an unfolded use position.
Patent CA-2341664-A1 (CA)
Title: Grafted poly(p-phenylene terephthalamide) fibers
Inventor: REBOUILLAT SERGE
IPC: D01F11/06
Filed: 1999-10-06
Abstract: Poly(p-phenylene terephthalamide) fibers are disclosed which have been grafted with nitrobenzyl, allyl, or nitrostilbene groups to increase adhesion of the fibers to rubber. A process for making the grafted fibers is, also, disclosed.
Patent CA-2346003-A1 (CA)
Title: Denture adhesive comprising partial, mixed ca/na salts of pve/ma copolymer
Inventor: CLARKE HAL CHRISTOPHER
IPC: A61K6/00
Filed: 1999-09-30
Abstract: A denture adhesive comprises a partial, mixed salt of a copolymer of an alky l vinyl ether and maleic acid copolymer produced by a wet process, wherein the  cations of said salt comprise i) calcium with a degree of substitution of th e copolymer in calcium of at least about 69 %; and ii) at least one other cati on selected from the group consisting of sodium and potassium.
Patent CA-2346336-A1 (CA)
Inventor: SCHULZ WOLFGANG
IPC: B23K26/02
Filed: 1999-03-13
Abstract: The invention relates to a method for shaping materials with plasma-inducing high-energy radiation, especially laser radiation. According to said method, the momentary intensity of the plasma radiation is measured in several places on a steam capillary. In order to be able to carry out the method for lower workpiece thicknesses with good welding results, the shapes of two maximum intensity regions (10, 12) located at a distance from each other, or of another electromagnetic beam emitted from the steam capillary, and the shape of a minimum region (11) that can be formed between these two regions with extreme values are determined using a measuring technique, the so determined shapes of the regions with the extreme values are compared with predetermined region shapes, and the material processing operation is controlled in dependence on the deviations of the determined shapes from the predetermined region shapes.
Patent CA-2351064-A1 (CA)
Inventor: LEHTINEN MATTI
IPC: A61K47/34
Filed: 1999-10-26
Abstract: The invention relates to a delivery device for the controlled release of a therapeutically active agent, especially an androgen, over a prolonged perio d of time, said device comprising a core comprising said therapeutically activ e agent, and a membrane encasing said core wherein said membrane is made of an  elastomer. According to the invention, the elastomer is a siloxane-based elastomer comprising 3,3,3-trifluoropropyl groups attached to the Si-atoms o f the siloxane units.
Patent CA-2355580-A1 (CA)
Title: Subtilase enzymes of the i-s1 and i-s2 sub-groups having an additional amino acid residue in the active site loop region
Inventor: ANDERSEN CARSTEN
IPC: C11D3/386
Filed: 1999-12-20
Abstract: Subtilase enzymes of the I-S1 and I-S2 sub-groups having an additional amino acid residue in position 99 of the active site loop (b) region from position 95 to 103. Variant subtilases exhibit improved wash performance in a detergent in comparison to its parent enzyme.
Patent CA-2355643-A1 (CA)
Title: Mounting hardware for a hard tonneau cover
Inventor: KATTERLOHER KURT
IPC: B60J7/08
Filed: 2000-02-08
Abstract: A hinge assembly (30) mounts a hard tonneau cover (26) on a vehicle having a storage area. The assembly (30) has a moveable hinge portion (32) adapted mounting on the tonneau cover and a stationary hinge portion (34) adapted for mounting to the vehicle. A guided member (48) co-acts with a guiding member (40, 42) for pivotally mounting the tonneau cover (26) to the vehicle about an axis of rotation between a closed position. The guiding member (40, 42) positions the axis of rotation of the tonneau cover (26) forwardly of an upper edge of the storage area allowing the forward edge of the tonneau cover to lift thereby minimizing damage to the peripheral seal (36).
Patent CA-2356002-A1 (CA)
Inventor: BALDWIN JOHN R
IPC: G01R31/327
Filed: 2001-08-27
Abstract: A system and method are provided for ensuring increased accuracy of individual relays (e.g., within a control system comprising a sensor) to close substantially coincidentally with respect to a current zero-crossing of an incoming power supply waveform. To determine timing of contact operation, a microcontroller operates the contacts in response to one of a series of test pulses, and determines the amount of time required for contact operation. The difference between timing of contact operation and zero-crossing is determined and adjusted to offset errors incurred by microcontroller threshold variations and power supply voltage variations. The calibrated value is then provided to the sensor in order to extend sensor life.
Patent CA-2357457-A1 (CA)
Title: Automatic film roll changer and method of operating the same
Inventor: TURFAN FARUK M
IPC: B65H19/12
Filed: 2001-09-19
Abstract: A new or fresh plastic film roll/depleted or exhausted plastic film roll tube or core exchange system comprises a plastic film roll dispenser mounting framework, a plastic film roll magazine assembly, and a new or fresh plastic film roll/depleted or exhausted plastic film roll tube or core exchange assembly. A supply of new or fresh plastic film rolls are serially mounted upon the new or fresh plastic film roll supply magazine, and the new or fresh plastic film roll/spent or exhausted plastic film roll core or tube exchange mechanism is utilized to remove a spent or exhausted plastic film roll core or tube from the plastic film roll dispenser mounting framework, remove a new or fresh plastic film roll from the supply magazine, and mount the new or fresh plastic film roll upon the plastic film roll dispenser mounting framework while the spent or exhausted plastic film roll core or tube is mounted upon the supply magazine.