baber/WOPTO huggingface dataset:
Patent CA-2868174-A1 (CA)
Title: Boronic acid conjugates of oligonucleotide analogues
Inventor: HANSON GUNNAR J
IPC: C12P19/34
Filed: 2013-03-07
Abstract: Oligonucleotide analogues comprising boronic acid and/or boronic ester moieties are provided. The disclosed compounds are useful for the treatment of diseases where inhibition of protein expression or correction of aberrant mRNA splice products produces beneficial therapeutic effects.
Patent CA-2871519-A1 (CA)
Title: Sporting footwear and system for enhancing force transfer
Inventor: BOURQUE ROBERT
IPC: A43B5/16
Filed: 2013-03-15
Abstract: A sporting footwear and system for enhancing a force transfer is described. The footwear enhances the force transfer from a foot of the wearer of the footwear, to a playing surface on which the footwear is being used. The footwear has a shell which receives and encloses the foot. The shell has a heel portion, and opposite sole and upper portions. The footwear also has a force-transferring member. The member has a first surface which can be attached to the inside of the upper portion, and an opposed second surface which can abut against the top of the wearer's foot when it is inserted into the shell. When the member abuts against the top of the foot, it fills a void and enables an increased operative contact surface within the footwear. This allows for enhanced force transfer between the foot and the shell of the footwear, and ultimately, the playing surface.
Patent CA-2872234-A1 (CA)
Inventor: SANDER CHRIS
IPC: G06G7/58
Filed: 2013-05-09
Abstract: The present invention relates to a method for predicting three-dimensional structure of a protein from its sequence. Three-dimensional structure may be determined by: (a) generating a multiple sequence alignment for a candidate protein having a known sequence; (b) identifying a covariance matrix between all pairs of sequence positions in the multiple sequence alignment; (c) inverting the covariance matrix and identifying predicted evolutionary constraints using a statistical model of the candidate protein; and (d) simulating folding of an extended chain structure of the candidate protein using the predicted constraints.
Patent CA-2874013-A1 (CA)
Title: Identification et blocage de publicites telles que des publicites competitives a documents specifiques
Inventor: AXE BRIAN
IPC: G06Q30/02
Filed: 2004-08-24
Abstract: Un partenaire de propriétaire de contenu (par exemple, un éditeur de site Web/page Web) peut facilement bloquer des catégories entières ou étroites dannonces et peut spécifier un contenu ou un ciblage publicitaire répréhensible. Les concepts peuvent être associés à une propriété et les annonces liées à ces concepts peuvent être bloquées pour la propriété donnée. En outre, des termes peuvent être associés à une propriété et les annonces qui comprennent lun de ces termes peuvent être bloquées pour la propriété donnée.
Patent CA-2878190-A1 (CA)
Title: Pharmaceutical composition for reducing the trimethylamine n-oxide level
Inventor: KALVINS IVARS
IPC: A61P13/12
Filed: 2013-10-24
Abstract: The invention discloses the use of pharmaceutical compositions containing 3-(2,2,2-trimethylhydrazinium)propionate, its dihydrate or pharmaceutically acceptable salts thereof for trimethylamine N-oxide level decrease in a body.
Patent CA-2880515-A1 (CA)
Inventor: MUKHERJEE UJJAL K
IPC: C10G65/02
Filed: 2013-07-15
Abstract: A process for upgrading residuum hydrocarbons and decreasing tendency of the resulting products toward asphaltenic sediment formation in downstream processes is disclosed. The process may include: contacting a residuum hydrocarbon fraction and hydrogen with a hydroconversion catalyst in a hydrocracking reaction zone to convert at least a portion of the residuum hydrocarbon fraction to lighter hydrocarbons; recovering an effluent from the hydrocracking reaction zone; contacting hydrogen and at least a portion of the effluent with a resid hydrotreating catalyst; and separating the effluent to recover two or more hydrocarbon fractions.
Patent CA-2880582-A1 (CA)
Inventor: TUNHEIM OLA
IPC: E21B17/01
Filed: 2013-09-10
Abstract: Disclosed are systems and methods for analyzing an oil/gas separation process. One disclosed system includes a flow path containing a fluid, a fluid separator coupled to the flow path and having an inlet for receiving the fluid and a discharge conduit for discharging the fluid after having undergone a separation process in the fluid separator, an optical computing device having an integrated computational element configured to optically interact with the fluid before the fluid enters the fluid separator and after the fluid exits the fluid separator and thereby generate optically interacted light, and at least one detector arranged to receive the optically interacted light and generate an output signal corresponding to a characteristic of the fluid.
Patent CA-2882826-A1 (CA)
Inventor: MCKNIGHT STEVEN L
IPC: A61P25/28
Filed: 2013-08-23
Abstract: Compounds and methods for stimulating neurogenesis (e.g., post-natal neurogenesis, including post-natal hippocampal and hypothalamic neurogenesis) and/or protecting neuronal cell from cell death are disclosed herein. In vivo activity tests suggest that these compounds may have therapeutic benefits in neuropsychiatric and/or neurodegenerative diseases such as schizophrenia, major depression, bipolar disorder, normal aging, epilepsy, traumatic brain injury, post-traumatic stress disorder, Parkinson's disease, Alzheimer's disease, Down syndrome, spinocerebellar ataxia, amyotrophic lateral sclerosis, Huntington's disease, stroke, radiation therapy, chronic stress, abuse of a neuro-active drug, retinal degeneration, spinal cord injury, peripheral nerve injury, physiological weight loss associated with various conditions, as well as cognitive decline associated with normal aging, chemotherapy, and the like.
Patent CA-2883191-A1 (CA)
Inventor: PAN YUANLONG
IPC: A23L33/00
Filed: 2013-08-22
Abstract: The invention provides methods for promoting weight loss by an animal, promoting weight loss by an animal while preventing or minimizing loss of lean body mass by the animal, preventing a reduction in energy metabolism by an animal, reducing the risk of regaining weight by an animal after weight loss, and ameliorating undesirable animal behaviors associated with reduced caloric intake by intermittently feeding an animal a first diet containing calories that meet the animal's maintenance energy requirements and a second diet containing calories that do not meet the animal's maintenance energy requirements. In preferred embodiments, the described feeding pattern and diets are fed in conjunction with one or more weight loss agents.
Patent CA-2885775-A1 (CA)
Title: Dispositif d'imagerie de topographie faciale avec photographie flash a sources lumineuses multiples et procede pour les melanger
Inventor: TAN JERRY K L
IPC: A61B5/00
Filed: 2012-09-26
Abstract: L'invention concerne un dispositif de capture d'images constitué d'une ou plusieurs sources lumineuses et d'un dispositif de capture d'images destiné à l'imagerie d'un visage humain. Le dispositif enrichit des informations topographiques en capturant une multitude d'images numériques d'un visage placé dans une orientation fixe avec des positions variables de sources lumineuses et en combinant les images à l'aide d'un algorithme de mélange. Il peut exister des sources lumineuses multiples ou une seule source lumineuse qui est repositionnée à chaque capture d'image de telle façon que les positions de la source lumineuse ne coïncident pas. L'algorithme de mélange peut être appliqué à un nombre quelconque d'images parmi un ensemble d'images acquises dans une orientation fixe, seule l'orientation de la source lumineuse étant variable. Le dispositif peut comprendre un dispositif d'appui servant à maintenir le visage humain dans une orientation fixe pendant la capture d'images.
Patent CA-2886189-A1 (CA)
Inventor: SCHIEF WILLIAM R
IPC: A61P31/14
Filed: 2013-04-04
Abstract: Polypeptides and compositions thereof are provided for treating or limiting metapneumovinjs (MPV) infection, as well as methods for designing such polypeptides. In further aspects, methods of using said isolated polypeptides, VLPs or pharmaceutical compositions are provided, which include methods for treating a metapneumovirus (MPV) infection, methods for limiting development of an MPV infection, methods for generating an immune response in a subject, methods for monitoring an MPV-induced disease in a subject and/or monitoring response of the subject to immunization by an MPV vaccine, methods for detecting MPV binding antibodies, methods for producing MPV antibodies, and methods of preventing an MPV infection.
Patent CA-2888794-A1 (CA)
Inventor: FOMIN VALENTIN
IPC: B23K26/24
Filed: 2013-10-21
Abstract: A robotically operated laser seam stepper is configured with an elongated support column extending along a longitudinal axis and made from lightweight material. A support plate is displaceably mounted to the column while supporting thereon an optical head which is provided with optics. The optics is configured to direct a laser beam along a path towards a welding zone through a protective window of the optical head. The laser seam stepper further is structured with a first arm mounted to the support plate and extending along a longitudinal axis of the stepper diametrically opposite to the optical head. The inner surface of the displaceable arm defines a tunnel which is aligned with the optical head and axially traversed by the laser beam, a first axially flowing stream of pressurized gaseous medium, and by a second axially flowing stream of gaseous medium. The second stream, entering the tunnel at a pressure lower than that one of the first stream in response to a pressure gradient generated in the column, does not generate vortexes within the column. The first and second streams exit through the downstream end of the tunnel next to the welding zone. As the streams flow out, they carry out welding debris from the tunnel.
Patent CA-2889652-A1 (CA)
Title: Work vehicle and control method for work vehicle
Inventor: SAKAI KATSUYUKI
IPC: H04Q9/00
Filed: 2014-07-30
Abstract: The present invention provides a work vehicle including a control system that can switch between a first driving mode for allowing the work vehicle to travel in a manned state and a second driving mode for allowing the work vehicle to travel in an unmanned state, wherein the control system controls such that, during an execution of the second driving mode, a number of types of information exchanged by communication in the control system becomes less than that during the first driving mode, or a communication interval of information exchanged by the communication in the control system becomes longer than that during the first driving mode.
Patent CA-2892029-A1 (CA)
Inventor: FOO KOK SENG
IPC: E21B7/12
Filed: 2013-11-22
Abstract: The present invention provides a structure-assisted Jackup system comprising a Jackup drilling unit with a main deck structure and a plurality of legs movably coupled with the main deck structure, one or more support base structures disposed on seabed, and a plurality of movable supports, wherein each of the plurality of movable supports is securely coupled with either the main deck structure or one or more support base structure. The present invention also provides a process for assembling the structure-assisted Jackup system.
Patent CA-2892062-A1 (CA)
Inventor: BALFE MICHAEL CHARLES
IPC: C01B32/50
Filed: 2015-05-20
Abstract: A carbon capture system comprising a Carbonator (2) for adsorbing carbon dioxide with a carbon dioxide lean sorbent generating a carbon dioxide rich sorbent, a first Calciner (1) for thermally decomposing a carbon dioxide rich sorbent into a carbon dioxide lean sorbent and carbon dioxide, a supply of raw material (4) to be calcined into the first Calciner (1) containing a carbon dioxide rich sorbent, a connection (13) between the first Calciner (1) and the Carbonator (2), a second Calciner (15) for thermally decomposing a carbon dioxide rich sorbent into a carbon dioxide lean sorbent and carbon dioxide, a connection (16) between the Carbonator (2) and the second Calciner (15), a connection (17) between the second Calciner (15) and the Carbonator (2).
Patent CA-2892295-A1 (CA)
Inventor: FINLEY DENNIS J
IPC: A63C1/32
Filed: 2015-05-20
Abstract: A skate blade for an ice hockey skate comprising a blade having an upper portion having a thickness corresponding to a standard skate blade and a lower portion having a pair of substantially parallel side walls defining a lower portion thickness of between 4.06 to 6.35 mm, the lower portion thickness extending from the bottom of the blade a height of 3.175 to 4.45 mm.
Patent CA-2893262-A1 (CA)
Inventor: LOTZ KATRIN
IPC: G06F19/00
Filed: 2013-12-05
Abstract: The present invention relates to a method for identifying at least one metabolic conversion step, the modulation of which increases the amount of a metabolite of interest in a plant cell, plant or plant part, said method comprising establishing a stoichiometric network model for the metabolism of the plant cell, plant or plant part including the synthesis pathway for the metabolite of interest,identifying at least one candidate metabolic conversion step by applying at least one algorithm of Growth-coupled Design, and validating the at least one candidate metabolic con- version step by a constraint-based modeling approach in the stoichiometric network model, wherein an increase in the metabolite of interest occurring in said constraint-based modeling approach is indicative for a metabolic conversion step, the modulation of which increases the amount of the metabolite of interest in the plant cell, plant or plant part. The present invention further relates to a method for generating a plant cell, plant or plant part which produces an in- creased amount of a metabolite of interest when compared to a control, said method comprising identifying a metabolic conversion step, the modulation of which increases a metabolite of inter- est in a plant cell, plant or plant part, by the method for identifying a metabolic conversion step and modulating the said metabolic conversion step such that the amount of the metabolite of interest is increased in vivo in a plant cell, plant or plant part.
Patent CA-2893751-A1 (CA)
Title: Method of measuring temperature of a heated part
Inventor: CHLEBOWSKI ROBERT
IPC: H05B6/06
Filed: 2015-06-03
Abstract: A method of measuring temperature of a part heated during a heating process includes applying a non-reactive coating at a first temperature; heating the part, and thereby the coating thereon, to a second temperature greater than the first temperature; and measuring a temperature distribution of the part by measuring infrared light emitted from the heated coating using a thermal imaging device calibrated to the known emissivity of the coating. The coating is at least partially opaque and having a known emissivity of infrared light and conducts thermal energy from the underlying part.
Patent CA-2893801-A1 (CA)
Title: Lna oligonucleotide carbohydrate conjugates
Inventor: ALBÆK NANNA
IPC: C12N15/113
Filed: 2014-01-30
Abstract: The invention provides LNA therapeutics oligonucleotide carbohydrate conjugates with considerably enhanced potency, extended therapeutic index and reduced toxicity.
Patent CA-2896861-A1 (CA)
Title: Formes de sels de meglumine de l'acide 2-((1r,4r)-4-(4-(5-(benzoxazol-2-ylamino)pyridin-2-yl)phenyl)cyclohexyl) acetique et leur utilisation comme inhibiteurs de dgat1
Inventor: CAPACCI-DANIEL CHRISTINA
IPC: A61P3/04
Filed: 2014-01-10
Abstract: La présente invention concerne de nouvelles formes cristallines de sels de méglumine de l'acide 2-((1R,4R)-4-(4-(5-(benzo[d]oxazol-2-ylamino)pyridin-2-yl)phényl)cyclohexyl)acétique : formule (I) et leur utilisation dans le traitement ou la prévention d'une affection ou d'un trouble associé à l'activité de DGAT1 chez des animaux, en particulier chez les humains.
Patent CA-2898470-A1 (CA)
Inventor: OTTO WILLIAM M
IPC: B64C25/34
Filed: 2014-01-15
Abstract: A main landing gear system for an aircraft including a truss element including a front portion joined to a rear portion, a first support unit and second support unit affixed to the truss at the junction of the first portion and the second portion on opposing sides of the truss, a first actuator and a second actuator rotatively affixed to respective first support unit and second support unit and to a respective first wheel and second wheel, a first trailing link and second trailing link each coupled to the respective first wheel and second wheel.
Patent CA-2898513-A1 (CA)
Inventor: HEATH STEPHAN
IPC: C08J3/20
Filed: 2015-07-27
Abstract: Methods, apparatus, products, and/or systems relating to making or using nanocrystalline (NC) products comprising a combination of one or more of nanocrystalline cellulose (NCC), nanocrystalline (NC) polymers, nanocrystalline (NC) plastics or other nanocrystals of cellulose composites or structures that have been processed into one or more of solid, flake, particles or other forms with vapor processing, solid state processing, liquid processing or other processing methods that can optionally be combined with other materials for different nanocrystalline (NC) applications, products or uses, and the like.
Patent CA-2902300-A1 (CA)
Title: Distance measuring system and distance measuring method
Inventor: KENZUME TATSUYA
IPC: G01C3/06
Filed: 2013-01-25
Abstract: The distance measurement system according to the present invention is provided with a reference member as a reference for distance measurement provided on a surface of a metal first pipe, an attachment member provided on a surface of a metal second pipe connected to the first pipe via a weld, a distance sensor attached to the attachment member for measuring the distance to the reference member, and a measurement unit for measuring the distance on the basis of an output from the distance sensor.
Patent CA-2902654-A1 (CA)
Inventor: JANTOS KATJA
IPC: A61P25/00
Filed: 2014-03-12
Abstract: The present invention relates to compounds of the formula I, the N-oxides, tautomers, the prodrugs and the pharmaceutically acceptable salts thereof: (I). In formula I the variables X1 is CH or N, X2 is O or S and where R1, R2, R3, R4 and Q are as defined in the claims. The compounds of the formula I, the N-oxides, tautomers, the prodrugs and the pharmaceutically acceptable salts thereof are inhibitors of phosphodiesterase type 10A. Thus, the invention also relates to the use of the compounds of the formula I, the N-oxides, tautomers, the prodrugs and the pharmaceutically acceptable salts thereof for the manufacture of a medicament and which thus are suitable for treating or controlling of medical disorders selected from neurological disorders and psychiatric disorders, for ameliorating the symptoms associated with such disorders and for reducing the risk of such disorders.
Patent CA-2903151-A1 (CA)
Inventor: HASCHEMI ARVAND
IPC: A61K31/7004
Filed: 2014-03-21
Abstract: The invention discloses sedoheptulose for use in the prevention or treatment of inflammation.
Patent CA-2903442-A1 (CA)
Inventor: MULLEN BRANDON S
IPC: B65D90/08
Filed: 2015-09-02
Abstract: A modular shipping container kit is configured to be assembled on-site by a user. The modular shipping container kit includes a roof, walls, and a floor which may be assembled to form a shipping container.
Patent CA-2905606-A1 (CA)
Title: Esters d'acide guanidinobenzoique utilises dans le traitement de troubles renaux
Inventor: FUJIYASU JIRO
IPC: A61K31/24
Filed: 2014-03-13
Abstract: L'invention a pour but de proposer un composé utile comme médicament pour prévenir et/ou traiter une maladie rénale. A cet effet, les inventeurs ont étudié des composés ayant une activité d'inhibition de la trypsine, ont confirmé que les composés ester d'acide guanidinobenzoïque ont une activité d'inhibition de la trypsine et ont accompli l'invention. Ces composés ester d'acide guanidinobenzoïque peuvent être utilisés comme médicaments pour la prévention et/ou le traitement de maladie rénale (par exemple maladie rénale chronique, glomérulonéphrite aiguë, insuffisance rénale aiguë et similaires) comme médicaments alternatifs à un régime faible en protéine et/ou comme médicaments pour la prévention et/ou le traitement de maladies dans lesquelles la trypsine participe (par exemple pancréatite chronique, sophagite par reflux, encéphalopathie hépatique, grippe et similaires).
Patent CA-2908347-A1 (CA)
Title: Liquid cooled die casting mold with heat sinks
Inventor: FLANNERY STEPHEN JOSEPH
IPC: B22D17/22
Filed: 2014-04-15
Abstract: A low pressure aluminum casting apparatus includes a pair of steel dies each presenting a molding surface and a heat transfer surface. Copper heat sink blocks are disposed on the heat transfer surfaces to remove heat from the steel dies. Steel contact plates and steel spacer plates can be disposed between the heat sink blocks and the steel dies to optimize cooling. In addition, a portion of each contact plate can be spaced from the steel die to reduce cooling. The steel dies include conventional cooling passages for conveying cooling fluid, and the heat sink blocks, contact plates, and spacer plates also include cooling channels for conveying cooling fluid.
Patent CA-2908952-A1 (CA)
Inventor: LORING MILES T
IPC: G06Q50/20
Filed: 2014-04-14
Abstract: La présente invention concerne des systèmes et des procédés de commande d'évaluation. Un système de commande d'évaluation peut être utilisé pour évaluer un ou plusieurs artefacts. Le système de commande d'évaluation peut être utilisé pour vérifier une évaluation et/ou pour réaliser un apprentissage d'évaluation. Le système d'évaluation peut comprendre un processeur et un dispositif d'utilisateur. Le système d'évaluation peut fournir un ou plusieurs artefacts et critères d'évaluation à un dispositif d'évaluation. Le système d'évaluation peut recevoir une ou plusieurs étiquettes associées aux artefacts et/ou aux critères d'évaluation. La ou les étiquettes peuvent comprendre des informations qui, en relation avec les critères d'évaluation, supportent une évaluation et/ou un score pour le ou les artefacts.
Patent CA-2909856-A1 (CA)
Title: Bottle and method of sterilization
Inventor: LEMBKE BRYAN J
IPC: B65D1/02
Filed: 2010-05-17
Abstract: A bottle includes a neck portion having an opening configured to permit filling and emptying of the bottle, a shoulder portion connected to a lower end of the neck portion, a sidewall connected to a lower end of the shoulder portion and extending vertically downward from the shoulder portion, and a base connected to a lower end of the sidewall and forming a bottom surface of the bottle. The sidewall has a plurality of annular ribs extending around a periphery of the sidewall. Each of the annular ribs includes a plurality of sequential enlarged portions interconnected by bridges, with each of the enlarged portions having a vertical width that is greater than a vertical width of each of the bridges.
Patent CA-2910733-A1 (CA)
Inventor: BAJKO GABOR
IPC: H04W16/14
Filed: 2013-04-29
Abstract: Methods and apparatus, including computer program products, are provided for white space database discovery. In one aspect there is provided a method. The method may include sending, by a user equipment, a request to a server including a white space database, wherein the server is located at a first address; and receiving, at the user equipment, a response to the request, the response including at least one of an identity of the server or a second address for accessing at least one of the server or another server including another white space database. Related apparatus, systems, methods, and articles are also described.