baber/WOPTO huggingface dataset:
Patent CA-2818635-A1 (CA)
Inventor: TIKHOMIROV ILIA
IPC: A61K47/48
Filed: 2011-12-02
Abstract: An erbB2 antibody is provided that binds preferentially to disease cells having an erbB2 density greater than a normal erbB2 density. The erbB2 antibody comprises a heavy chain and a light chain. Each chain has a constant region and a variable region. Each variable region comprises framework regions and complementarity determining regions (CDRs), wherein the CDRs have an amino acid sequence set forth below: For the heavy chain: CDR1 GFNIKDTYIH (SEQ ID No. 1) CDR2 RIYPTNGY57TR59 YADSVKG (SEQ ID No. 2) CDR3 WGGDGFYAMDY (SEQ ID No. 3) For the light chain: CDR1 RASQDVN30TAVA (SEQ ID No. 4) CDR2 SASF53LYS (SEQ ID No. 5) CDR3 QQHY92TTPPT (SEQ ID No. 6). At least one of Y57, R59, N30, F53, and Y92 is substituted by an amino acid that confers on said antibody a reduced erbB2 binding affinity (Kd) that is in the range from 0.1 nM to 100 nM. The substitution is other than N30A, F53N, Y92A and Y92F when there is a single substitution in the antibody light chain.
Patent CA-2818666-A1 (CA)
Title: A catcher ring arrangement
Inventor: MACKIE KENNETH JOHN
IPC: B64C27/48
Filed: 2013-06-12
Abstract: This invention relates to a blade assembly comprising: a hub which is rotatable about an axis; at least one blade having an aerofoil portion and a root, wherein the root is coupled to the hub using a primary retention device which prevents radial separation of the root and hub in normal use; and, a secondary retention device which comprises an annular catcher having a restriction through which the root portion cannot radially pass, the restriction being located radially outwardly and radially spaced from the root part during use.
Patent CA-2819774-A1 (CA)
Title: Composite pipe
Inventor: JONES MARTIN PETER WILLIAM
IPC: F16L11/08
Filed: 2011-12-05
Abstract: A pipe (200) comprises a pipe wall (202) formed of a composite material of a matrix and a plurality of reinforcing fibres embedded within the matrix. At least one longitudinal portion (204) of the pipe wall (202) comprises or defines a local variation in construction to provide a variation in a property of the pipe (200).
Patent CA-2822073-A1 (CA)
Title: Independent blade control system with hydraulic pitch link
Inventor: FENNY CARLOS A
IPC: F04D29/36
Filed: 2013-07-24
Abstract: According to one embodiment, a rotorcraft pitch link includes a housing and a piston assembly. The housing comprises a first chamber and a second chamber. A  first housing opening allows a first fluid to flow into the first chamber, and a second housing allows a second fluid to flow into the second chamber. The piston assembly is at least partially disposed within the housing and comprises a piston head and a piston rod coupled to the piston head. The piston head separates the first chamber from the second chamber.
Patent CA-2822387-A1 (CA)
Title: Geodesic measuring device comprising a thermographic camera
Inventor: ZIMMERMANN JAN
IPC: G01C7/00
Filed: 2012-01-10
Abstract: The invention relates to a method for determining, with geodesic precision, the position of a target point on a target object (15) by using a geodesic measuring device (1), said method comprising a sighting device, particularly a target telescope, which can be pivoted in relation to a base of the measuring device in order to alter its alignment, and which sighting device comprises at least one objective unit that defines an optical line of sight, an electronic distance measuring unit, and a thermal imaging camera for recording a thermal image in the direction of the optical line of sight. In addition, an angle measuring function is provided for recording, with high precision, the line of sight alignment, and a control unit is provided for controlling the angle measuring function, the thermal imaging camera, and particularly the alignment of the sighting unit. According to the invention, in a thermal imaging mode when a measurement procedure is triggered, position data of the sighted target point which are determined in said measurement procedure are linked to temperature information which is read out from the thermal image for the target point at which the line of sight is aimed. In particular, the position data of the target point is stored in correlation with the temperature information.
Patent CA-2823332-A1 (CA)
Inventor: PAVEL STEPHEN K
IPC: B01J8/18
Filed: 2011-12-29
Abstract: [000180] A method, system, and apparatus for lift gas distribution are disclosed. According to one embodiment, a lift gas distributor comprises a plate having a surface and an underside, the plate having a first diameter; a center section of the plate having a second diameter, wherein the first diameter is larger than the second diameter; a predetermined number of holes having a third diameter drilled into the surface of the plate, the holes drilled at an angle, the holes evenly distributed in the center section; and a plurality of tubes welded onto the underside of the plate, each tube having a predetermined length, wherein each tube is welded onto each hole. Lift gas passes through the tubes and holes into a reactor.
Patent CA-2825386-A1 (CA)
Title: Apparatus and method for control of a thermostat
Inventor: ALHILO ESAN A
IPC: H05B1/02
Filed: 2009-10-20
Abstract: A thermostat is provided that includes a temperature sensor for sensing ambient temperature, and a switching device that is configured to apply electrical power to a heating element when the switching device is activated. The thermostat further includes a processor that is configured to periodically determine for a finite switching time period a temperature delta value indicative of the difference between the sensed temperature and a desired set point temperature. The processor is further configured to calculate a duty cycle ratio of the switch activation time relative to the total switching time period.  The calculated duty cycle ratio for determining the switch activation time is determined as a function of the temperature delta value, a duty cycle offset and a heat dissipation offset. The duty cycle offset and the heat dissipation offset are based on an average of a predetermined number of prior duty cycle ratios.
Patent CA-2826248-A1 (CA)
Inventor: ARNAUDOV LUBEN NIKOLAEV
IPC: A23L23/00
Filed: 2012-01-31
Abstract: The present invention has as an objective to provide aerated food products containing hydrophobins, and proteins which do not interfere with hydrophobins, and of which the texture remains stable during storage. This objective is met by an aerated food product which contains aggregated protein particles which are not surface active.
Patent CA-2828055-A1 (CA)
Inventor: LIENENKAMP JORG
IPC: G01F23/00
Filed: 2012-02-21
Abstract: The invention relates to a device (1) which uses ultrasound to measure the filling level for liquids in a tank (2). The device (1) consists of a housing (3) in which a piezoelectric disc (4) connected to a circuit board (5) and an energy store (6) is provided. A display unit (8) is arranged in said housing (3), and on the side of the piezoelectric disc (4) that faces the tank (2), said disc is given a layer (11) consisting of elastic material.
Patent CA-2832281-A1 (CA)
Title: Anti-cd154 antibodies having impaired fcr binding and/or complement binding properties and the use thereof in immune therapies
Inventor: NOELLE RANDOLPH J
IPC: A61P37/06
Filed: 2012-04-04
Abstract: Improved anti-CD154 antibodies are provided herein which have ablated FcR binding. The use of these antibodies for inducing tolerance and treating immune diseases including autoimmunity, inflammation and allergic disorders is disclosed herein.
Patent CA-2835166-A1 (CA)
Inventor: STUMPF THOMAS
IPC: C22B5/12
Filed: 2012-05-03
Abstract: The method is used to obtain metals, noble metals, and rare earth metals from scrap. The aim of the invention is to provide a method that allows an efficient recovery even from electronic scrap. This is achieved in that the scrap and carbon-containing materials (A) are oxidized with oxygen-containing gases (11) in the presence of alkaline materials under overall reducing conditions with an overall lambda of <1 in an updraft gasifier (2) with a bulk material moving bed, said gasifier having a reduction zone (13) and an oxidation zone (7). The resulting syngas is drawn at the upper part (16) of the updraft gasifier, and the metals, noble metals, and rare earth metals are bound at least partly to the alkaline materials as oxides and/or in elementary form. Finally, said metals are obtained from the process as an enriched mixture (B) by means of physical separation methods.
Patent CA-2838006-A1 (CA)
Title: Method for producing hydrogels
Inventor: SANNINO ALESSANDRO
IPC: A23L29/20
Filed: 2012-06-07
Abstract: The present invention provides a method of producing a polymer hydrogel comprising the steps of: (1) preparing an aqueous solution of a water soluble polysaccharide derivative and a polycarboxylic acid; (2) optionally agitating the solution, for example, by stirring; (3) isolating a polysaccharide derivative/polycarboxylic acid composite from the solution; and (4) heating the polysaccharide derivative/polycarboxylic acid composite at a temperature of at least about 80 °C, thereby cross-linking the polysaccharide with the polycarboxylic acid. The invention also provides polymer hydrogels produced by the methods of the invention.
Patent CA-2838504-A1 (CA)
Title: A conjugate comprising oxyntomodulin and an immunoglobulin fragment, and use thereof
Inventor: JUNG SUNG YOUB
IPC: A61K47/48
Filed: 2012-06-15
Abstract: The present invention relates to a conjugate comprising oxyntomodulin, an immunoglobulin Fc region, and non-peptidyl polymer wherein the conjugate being obtainable by covalently linking oxyntomodulin to immunoglobulin Fc region via non-peptidyl polymer, and a pharmaceutical composition for the prevention or treatment of obesity comprising the conjugates. The conjugate comprising oxyntomodulin and the immunoglobulin Fc of the present invention reduces food intake, suppresses gastric emptying, and facilitates lipolysis without side-effects, unlike native oxyntomodulin, and also shows excellent receptor-activating effects and long-term sustainability, compared to native oxyntomodulin. Thus, it can be widely used in the treatment of obesity with safety and efficacy.
Patent CA-2842375-A1 (CA)
Title: Neuregulin antibodies and uses thereof
Inventor: JACKSON ERICA
IPC: A61P35/00
Filed: 2012-08-16
Abstract: The invention provides anti-neuregulin1 antibodies and methods of using the antibodies in treating diseases or disorders, such as cancer. In a particular embodiment, the anti-neuregulin1 antibodies bind to both neuregulin1a and neuregulin 1ß isoforms.
Patent CA-2842466-A1 (CA)
Inventor: COMEROTA ANTHONY J
IPC: A61M25/01
Filed: 2012-08-02
Abstract: An infusion catheter assembly has the ability to infinitely titrate the length of a porous fluid distribution section in situ. The infusion catheter assembly thereby provides a length of infusion that can be infinitely varied over a prescribed range, to control the effective infusion length and the rate of infusion. Using the infusion catheter assembly, a physician has the capability to treat only the length of the vessel desired, thereby preventing excessive drug/patient exposures. The porous fluid distribution section can include an array of spaced apart apertures that vary in size and/or density along the length of the porous fluid distribution section, such that the flow rate remains essentially constant for a given inlet pressure independent of the effective infusion length.
Patent CA-2843069-A1 (CA)
Inventor: COUTELOU OLIVIER
IPC: G01R21/133
Filed: 2012-08-02
Abstract: Ce système (20) est adapté pour mesurer l'énergie électrique du courant circulant dans au moins un conducteur secondaire (42A, 44A, 46A,..., 42N, 44N, 46N) relié à un conducteur primaire (34, 36, 38), les conducteurs primaire (34, 36, 38) et secondaires (42A,..., 46N) présentant la même tension. Ce système de mesure (20) comprend un module primaire (60) comportant un émetteur radioélectrique (70) et un organe (66) de mesure de la tension du conducteur primaire (34, 36, 38), au moins un module secondaire (62A,..., 62N) comportant un récepteur radioélectrique (80A,..., 80N), un capteur (76A,..., 76N) de l'intensité du courant dans le conducteur secondaire (42A,..., 46N) et un organe (126A,..., 126N) de calcul de l'énergie électrique dudit courant dans le conducteur secondaire. Le module primaire (60) comporte des premiers moyens (104) de compression de la valeur de la tension mesurée (V1, V2, V3) et des moyens (106) d'émission à chaque module secondaire (62A,..., 62N) d'un message (M1) contenant la valeur compressée de la tension mesurée. Le système de mesure (20) comprend des moyens (106, 120A, 120N, 122A,..., 122N) de synchronisation temporelle de chaque capteur de l'intensité (76A,..., 76N) par rapport à l'organe de mesure de la tension (66). L'organe de calcul (126A,..., 126N) est relié au récepteur radioélectrique (80A,..., 80N) et propre à calculer l'énergie électrique à partir de la valeur de la tension reçue du module primaire (60) et de la valeur de l'intensité mesurée.
Patent CA-2845275-A1 (CA)
Title: Ophthalmic formulations
Inventor: CRAWFORD FRANCESCA
IPC: A61K33/18
Filed: 2012-08-24
Abstract: There is provided inter alia a germicidal aqueous formulation, suitable for use in the eye, which has a pH of from 4.0 to 6.5 and which comprises 4.0 to 7.5% w/w of povidone-iodine and a viscosity increasing agent, the formulation buffered with a buffer concentration of 25 mM to 75 mM.
Patent CA-2845284-A1 (CA)
Inventor: BORUAH ANIMA
IPC: A61P3/06
Filed: 2012-08-17
Abstract: The present application relates to cycloalkylpyridin-2-amines derivates of formula (1) or stereoisomers thereof or pharmaceutically acceptable salts thereof. The present application also relates to the process for the preparation of compounds of formula (I). The present application further describes the compounds of formulat (1) as cholesteryl ester-transfer protein (CETP) inhibitors. The present application further relates to pharmaceutical compositions comprising compounds of formula (1) or stereoisomers thereof or pharmaceutically acceptable salts thereof.
Patent CA-2848208-A1 (CA)
Inventor: FATTORI JOSEPH
IPC: A61C17/22
Filed: 2012-09-13
Abstract: A refill head (100), and oral care implement incorporating the same, wherein the refill head (100) can be uncoupled from a stem (220) of a handle (200) by withdrawing the refill head (100) from the stem of a handle (200) along the longitudinal axis of the oral care implement, which results in locking members (134) on the refill head (100) disengaging from an engagement rib (230) on the stem (220). The locking members (134) and engagement rib (230) may be aligned with or angled relative to the longitudinal axis of the oral care implement. A portion of the stem may be visible through a portion of the refill head to reinforce the proper connection between the refill head and the handle.
Patent CA-2848415-A1 (CA)
Inventor: CHANG YU-HWA
IPC: C10G47/06
Filed: 2012-09-19
Abstract: Methods and systems for hydrocracking a heavy oil feedstock include using a colloidal or molecular catalyst (e.g., molybdenum sulfide) and provide for concentration of the colloidal or molecular catalyst within the lower quality materials requiring additional hydrocracking in one or more downstream reactors. In addition to increased catalyst concentration, the inventive systems and methods provide increased reactor throughput, increased reaction rate, and of course higher conversion of asphaltenes and lower quality materials. Increased conversion levels of asphaltenes and lower quality materials also reduces equipment fouling, enables the reactor to process a wider range of lower quality feedstocks, and can lead to more efficient use of a supported catalyst if used in combination with the colloidal or molecular catalyst.
Patent CA-2853414-A1 (CA)
Inventor: MARQUES FREDERIC
IPC: H02P3/04
Filed: 2012-11-21
Abstract: An actuator comprising at least one multiphase motor (100) having phases (101) facing a rotor (102) secured to an outlet shaft associated with a braking member (2) and provided with means for connecting it to a movable element that is to be moved, the motors and the braking member being connected to at least one motor control unit (5) for controlling the motors by powering their phases. The motor has at least four phases wound in such a manner as to avoid a neutral point, and in that the control unit has one single-phase inverter per phase and is arranged to implement a nominal, three-phase mode of control, and a degraded mode of control that enables the rotor to be driven in rotation by powering two non-collinear phases thereof.
Patent CA-2856734-A1 (CA)
Title: A kit for a heating applicator and product
Inventor: BOUIX HERVE F
IPC: A45D34/04
Filed: 2012-12-11
Abstract: A heating applicator kit for mascara or other products that tend to dry out or be adversely affected when heated. A kit comprises multiple reservoirs of product and at least one heating applicator that alleviates the problems associated with heat exposure in the reservoir and on the applicator head.
Patent CA-2857357-A1 (CA)
Title: Geared turbofan gas turbine engine architecture
Inventor: HOUSTON DAVID P
IPC: F02K3/02
Filed: 2013-01-30
Abstract: A gas turbine engine includes a fan rotatable about an axis, a compressor section, a combustor in fluid communication with the compressor section, and a turbine section in fluid communication with the combustor. The turbine section includes a fan drive turbine and a second turbine. The second turbine is disposed forward of the fan drive turbine. The fan drive turbine includes at least three rotors and at least one rotor having a bore radius (R) and a live rim radius (r), and a ratio of r/R is between about 2.00 and about 2.30. A speed change system is driven by the fan drive turbine for rotating the fan about the axis.
Patent CA-2857698-A1 (CA)
Title: Method for producing a cable core, having a conductor surrounded by an insulation, for a cable, in particular for an induction cable, and cable core and cable
Inventor: MOSEBACH JENS
IPC: E21B43/24
Filed: 2012-11-29
Abstract: The invention relates to a production method for producing a cable core (2) for an induction cable (24) in a simple and simultaneously reliable manner, in which a raw conductor (14) is fed continuously to a processing machine (38) and separated in a recurring manner at specified length positions at a separating point (6) so that there are two wire ends (16). Said ends are then pulled apart from each other in the longitudinal direction of the cable (4) and then connected again by a connector (8) which has an insulating spacer (20) which separates the wire ends (16) from each other by a specified distance. The connector (8) is preferably designed as an injection molded part, in particular using the online process. A plurality of such cable cores (2) are connected to each other via a cabling process and then enclosed by a cable sleeve (34) to produce the induction cable (24).
Patent CA-2858194-A1 (CA)
Inventor: HEDTKE ROBERT CARL
IPC: G01F1/34
Filed: 2012-11-07
Abstract: A pressure transmitter for measuring a pressure of a process fluid comprises a transmitter housing, a pressure sensor, a hydraulic relay system, a ferrofluid and transmitter electronics. The capacitance-based pressure sensor senses the pressure of the process fluid and is disposed within the housing. The hydraulic relay system comprises an isolation diaphragm positioned on an exterior of the transmitter housing, and an isolation tube extending from the pressure sensor to the isolation diaphragm. The ferrofluid is located in the isolation tube to transmit a change in the pressure of the process fluid at the isolation diaphragm to the sensor. The transmitter electronics are positioned within the housing and are configured to receive and condition a pressure signal from the pressure sensor.
Patent CA-2858401-A1 (CA)
Title: Controle par ultrasons
Inventor: SKOGLUND ESKIL
IPC: G01S15/89
Filed: 2014-08-05
Abstract: Un appareil permettant deffectuer limagerie des caractéristiques structurelles sous la surface dun objet, lappareil étant constitué dune unité de transmission configurée pour transmettre des impulsions sonores au niveau de lobjet; dune unité de réception configurée pour recevoir les réflexions des impulsions sonores transmises par lunité de transmission au niveau de lobjet; dune unité de traitement des signaux configurée pour : analyser un ou plusieurs signaux reçus de lobjet par lunité de réception; reconnaître, dans un ou plusieurs signaux, une réflexion causée par une première caractéristique structurelle et une réflexion causée par une deuxième caractéristique structurelle qui est située, dans lobjet, au moins partiellement derrière la première caractéristique structurelle; et associer chaque réflexion reconnue à une profondeur relative de lobjet duquel la réflexion provient; et dune unité de génération dimages configurée pour générer une image comprenant une représentation des première et deuxième caractéristiques structurelles en fonction des réflexions reconnues et de leurs profondeurs relatives.
Patent CA-2858929-A1 (CA)
Title: Drier for auto-oxidisable coating compositions
Inventor: MEIJER MICHEL DANIEL
IPC: C09D7/63
Filed: 2012-12-17
Abstract: A drier for air-drying an auto-oxidizable resin composition, said drier comprising: 1,4,7trialkyl- 1,4,7-triazacyclononane (L); a manganese salt having the general formula Mn2+[X]n, wherein anion X is selected from PF6 -, SbF6 -, AsF6 -, BF4 -, B(C6F5)4 -, CI-, Br-, I-, NO3, or R2COO- in which case n=2, or the anion X is SO4 2- in which case n=1, and wherein R2 is C1-C20 alkyl optionally substituted with heteroatoms, C6-C20 aryl optionally substituted with heteroatoms, or a polymeric residue; wherein the 1,4,7trialkyl-1,4,7-triazacyclononane (L) is present in the mixture in an amount such that the molar ratio of Mn:L is at least 1.25:1 and preferably at least 1.5:1.
Patent CA-2860147-A1 (CA)
Inventor: MANSON SCOTT M
IPC: G05D17/00
Filed: 2012-12-11
Abstract: A system for managing an electric power delivery system is disclosed that includes a set of remote intelligent electronic devices (lEDs) and a central lED. The remote lEDs may be configured to obtain information related to rotor angles, operating frequencies, rate of change of frequency, rotating inertia, and power consumption levels of loads and generators included in the electric power delivery system. The central lED may communicate with the remote lEDs to determine which loads and generators are associated with a sub-grid of the electric power delivery system and whether to disconnected certain loads or generators. Based on this determination, the central lED may direct the remote lEDs to disconnect loads or generators from the electric power delivery system, or to rapidly increase or decrease generator output as appropriate.
Patent CA-2860313-A1 (CA)
Inventor: FRIESEN PETE
IPC: A01B63/00
Filed: 2014-08-21
Abstract: A combined fifth wheel lift and slider assembly mountable on a truck frame includes a fifth wheel slidably mounted upon a fifth wheel slider assembly, and vertically elevatable by a frame member; the frame member supporting the fifth wheel slider assembly, the frame member being moveable from a resting position wherein the frame member rests substantially horizontal relative to the truck frame, to an actuating position wherein the frame member is positioned at an angle relative to the truck frame; a hydraulic mechanism for moving the frame member from the resting position to the actuating position wherein the hydraulic mechanism extends upwardly to push the frame member, the fifth wheel assembly, and the fifth wheel in a direction away from the truck cab; and locking means for securing the frame member in the resting position.