Patent DE-102009028001-A1 (DE)
Title: Use of an active agent combination (comprising a 3-phenyl-1-aza-spiro(4.5)dec-3-en-2-one compound, and an agent e.g. alanycarb, aldicarb, acephate, camphechlor or chlordane) for combating animal pests e.g. insects, acarids and helminths
Inventor: FISCHER REINER
IPC: A01P7/04
Filed: 2009-07-24
Abstract: Use of an active agent combination (comprising at least a 3-phenyl-1-aza-spiro[4.5]dec-3-en-2-one compound (I), and one or more further insecticidal and/or acaricidal agent) for combating animal pests, is claimed, where the insecticidal and/or acaricidal agent comprises e.g. acetylcholinesterase inhibitors, which are carbamates e.g. alanycarb, aldicarb, aldoxycarb or bufencarb, and organophosphate e.g. acephate, azamethiphos, bromophos-ethyl or cadusafos, or gamma-aminobutyric acid controlled chloride channel antagonists, which are organochlorine e.g. camphechlor or chlordane. Use of an active agent combination (comprising at least a 3-phenyl-1-aza-spiro[4.5]dec-3-en-2-one compound of formula (I), and one or more further insecticidal and/or acaricidal agent) for combating animal pests, is claimed, where the insecticidal and/or acaricidal agent comprises acetylcholinesterase inhibitors, which are carbamates e.g. alanycarb, aldicarb, aldoxycarb, allyxycarb or bufencarb, and organophosphate e.g. acephate, azamethiphos, bromophos-ethyl, butathiofos or cadusafos; gamma-aminobutyric acid controlled chloride channel antagonists, which are organochlorine e.g. camphechlor, chlordane, endosulfan, heptachlor or methoxychlor, or fiprole, which is acetoprole, ethiprole, fipronil, pyrafluprole or pyriprole; sodium channel modulators/voltage-gated sodium channel blockers, which are pyrethroid e.g. acrinathrin, allethrin, bifenthrin, bioallethrin, biopermethrin, cycloprothrin, cyfluthrin, cyhalothrin, deltamethrin or empenthrin; nicotinic acetylcholine receptor agonists/antagonists, which are chloronicotinyl e.g. acetamiprid, clothianidin, dinotefuran, imidacloprid, imidaclothiz, nicotine, bensultap, cartap, thiocyclam or sodium thiosulfate; allosteric acetylcholine receptor modulators, which are spinosyn, preferably spinosad or spinetoram; chloride channal activators, which are mectin/macrolide, preferably abamectin, emamectin, emamectin-benzoate, ivermectin, lepimectin or milbemectin; juvenile hormone analog e.g. hydroprene, kinoprene, methoprene, epofenonane, triprene, fenoxycarb or diofenolan; and substances with unknown or unspecific mechanisms of action, e.g. fumigant e.g. chloropicrin or sulfuryl fluoride, selectice feeding inhibitors e.g. cryolite or pymetrozine, mite growth inhibitors e.g. clofentezine or etoxazole, inhibitors of oxidatice phosphorylation e.g. diafenthiuron, azocyclotin or tetradifon, uncoupling of oxidative phosphorylation through interruption of H-proton gradients e.g. chlorfenapyr, binapacryl, or dinocap, microbial disruptors of insect intestinal membrane e.g. Bacillus thuringiensisstrains, inhibitors of chitin biosynthesis e.g. bistrifluron, chlorfluazuron, diflubenzuron, fluazuron or flucycloxuron, disturbing skinning agents, such as cyromazine, disruptors ecdysone agonists e.g. chromafenozide or halofenozide, octopaminergic agonist e.g. amitraz, side-III-electron transport inhibitors/side-II-electron transport inhibitors e.g. fenazaquin, fenpyroximate or pyrimidifen, voltage-gated sodium channel blockes e.g. indoxacarb, inhibitors of fatty acid biosynthesis e.g. spirodiclofen or spirotetramat, neuronal inhibitors with unknown active mechanisms e.g. bifenazate, ryanodine receptor effectors e.g. flubendiamide or chlorantraniliprole or active agent with unknown mechanisms e.g. amidoflumet, benclothiaz or benzoximate, pyridalyl or sulfluramid. W 1>H, alkyl, alkenyl, alkynyl, halo, alkoxy, haloalkyl, haloalkoxy or CN; X : halo, alkyl, alkenyl, alkynyl, alkoxy, haloalkyl, haloalkoxy, nitro or CN; Y 1>, Z : H, alkyl, alkenyl, alkynyl, alkoxy, halo, haloalkyl, haloalkoxy, CN or nitro; AB 1>C : 5-7-membered ketal, thioketal or dithioketal ring (all optionally interrupted by further heteroatoms and optionally substituted by alkyl, haloalkyl, alkoxy, alkoxyalkyl, or optionally substituted phenyl); G : H, -C(=O)-R 1>, -C(=L)-M-R 2>, -SO 2-R 3>, -P(=L)(R 4>)(R 5>), E or -C(=L)-N(R 6>)(R 7>); E : metal ion or ammonium ion; L, M : O or S; R 1>alkyl, alkenyl, alkoxyalkyl, alkylthioalkyl or polyalkoxyalkyl (all optionally substituted by halo or CN), cycloalkyl or heterocyclyl (both optionally substituted by halo, alkyl or alkoxy) or phenyl, phenylalkyl, heteroaryl, phenoxyalkyl or heteroaryloxyalkyl (all optionally substituted); R 2>alkyl, alkenyl, alkoxyalkyl or polyalkoxyalkyl (all optionally substituted by halo or CN) or cycloalkyl, phenyl or benzyl (all optionally substituted); R 3>-R 5>phenyl, benzyl, phenoxy or phenylthio (all optionally substituted), or alkyl, alkoxy, alkylamino, dialkylamino, alkylthio, alkenylthio or cycloalkylthio (all optionally substituted by halo); and either R 6>, R 7>alkyl, cycloalkyl, alkenyl, alkoxy, alkoxyalkyl (all optionally substituted by halo or CN), phenyl or benzyl (both optionally substituted) or H; or R 6>R 7>N : optionally substituted cycle, which optionally contains O or S. [Image] ACTIVITY : Insecticide; Acaricide; Anthelmintic; Nematocide; Fungicide; Antibacterial; Virucide. MECHANISM OF ACTION : None given.