baber/WOPTO huggingface dataset:
Patent PT-1970060-E (PT)
Title: Use of c-(2-phenyl-cyclohexyl)-methylamine compounds for fibromyalgia therapy
Inventor: HENNIES HAGEN-HEINRICH
IPC: A61K31/137
Filed: 2004-11-26
Abstract: The use of eleven specific C-(2-phenyl-cyclohexyl)-methylamine compounds (I) (all preferably in 1R,2R-enantiomer form), e.g. 3-(2-dimethylaminomethyl-cyclohexyl)-phenol (Ia) or (2-(3-methoxyphenyl)-cyclohexylmethyl)-dimethylamine, as medicaments for treating anxiety disorders or as adjuvant for standard antidepressants is new. The use of C-(2-phenyl-cyclohexyl)-methylamine compounds (I) is claimed in the production of medicaments for treating anxiety disorders and in the production of adjuvants for standard antidepressants. (I) is selected from 3-(2-dimethylaminomethyl-cyclohexyl)-phenol (Ia), (2-(3-methoxyphenyl)-cyclohexylmethyl)-dimethylamine, sulfuric acid mono-(3-(2-dimethylaminomethyl-cyclohexyl)-phenyl) ester, 3-(2-methylaminomethyl-cyclohexyl)-phenol, 3-(2-dimethylaminomethyl-cyclohexyl)-phenol N-oxide, 6-(3-(2-dimethylaminomethyl-cyclohexyl)-phenoxy)-3,4,5-trihydroxy-tetrahydropyran-2-carboxylic acid, 4-(2-dimethylaminomethyl-cyclohexyl)-catechol, 3-(2-aminomethyl-cyclohexyl)-phenol, C-(2-(3-methoxyphenyl)-cyclohexyl)-methylamine, (2-(3-methoxyphenyl)-cyclohexylmethyl)-methylamine and (2-(3-methoxyphenyl)-cyclohexylmethyl)-dimethylamine N-oxide. All compounds are optionally in the form of racemates or pure stereoisomers (specifically enantiomers or diastereomers) or their mixtures in all proportions; and/or in the form of salts or solvates (specifically hydrates). (I) are preferably in 1R,2R-enantiomer form. ACTIVITY : Tranquilizer; antidepressant; analgesic. In 'elevated plus maze' tests for anxiolytic activity in rats (see Psychopharmagcology, 2002, 163, 121-141), 3-(2-dimethylaminomethyl-cyclohexyl)-phenol (Ia) gave residence time of 118.2 seconds at a dose of 16 mg/kg, compared with 16.8 seconds in vehicle-only controls. MECHANISM OF ACTION : psi -Opiate agonist; serotonin reuptake inhibitor; noradrenaline reuptake inhibitor. (Ia) had K i values of 0.14 mu M, 0.05 mu M and 0.16 mu M in mu -opioid affinity, serotonin reuptake inhibiting and noradrenaline reuptake inhibiting assays respectively.
Patent PT-2074908-E (PT)
Title: Shoe rack
Inventor: CHIANG HSIAO-HUNG
IPC: A47B57/26
Filed: 2008-03-07
Abstract: A shoe rack includes subassemblies comprising a lower support (10) including an upward extending sleeve (11) passing a rear end and having a ridged inner wall (114), an annular top projection (112A) extending inward, and an annular intermediate projection (112B) extending inward from the wall (114); and an upper support (20) including a hollow cylinder (21) passing a rear end, the cylinder (21) having an outer ridged structure (212), an annular top groove (211A) on the ridged structure (212), and an annular intermediate groove (211B) on the ridged structure (212) wherein the cylinder (21) inserts into the sleeve (11) to be pivotably secured thereto by engaging the top groove (211A) with the top projection (112A) and the intermediate groove (211 B) with the intermediate projection (112B) or engaging the intermediate groove (211B) with the top projection (112A); and a pole (31) passing the sleeves (11) and the cylinders (21).
Patent PT-2196116-E (PT)
Title: Drive for a coffee brewing device and coffee brewing device
Inventor: BUETTIKER PHILIPP
IPC: A47J31/36
Filed: 2009-12-05
Abstract: The drive (1) has a gear wheel with an internal thread by which the gear wheel is rotatably supported at an external thread (21) of a guide cylinder (20) so that the gear wheel is movable during a rotation along a cylinder axis (22) of the guide cylinder. A linear guide (80) is provided for guiding a housing (50), which runs at a distance parallel to cylinder axis. The linear guide stands in contact with the housing so that movement of the housing against the linear guide in radial direction to the cylinder axis is prevented. An independent claim is also included for a coffee brewing device with a damping element.
Patent PT-2274978-E (PT)
Title: Methods for treatment of insulin-like growth factor-i(igf-i) deficiency
Inventor: CLARK ROSS G
IPC: A61P5/00
Filed: 2004-09-09
Abstract: The present invention provides methods and compositions for increasing the growth rates, alleviating the symptoms, or improving the metabolism of human patients having insulin-like growth factor-1 deficiency (IGFD). The invention relates to methods comprising administering insulin-like growth factor-I to a patient having a height which, at the time of treatment or prior to initial treatment with IGF-1, is at least about 2 standard deviations below normal for a subject of the same age and gender, a blood level of insulin-like growth factor-I that, and at the time of treatment or prior to initial treatment with IGF-1, is below normal mean levels, usually at least about 1 standard deviations below normal mean levels, for age and gender.
Patent PT-769056-E (PT)
Inventor: JACKMAN WINTHROP T
IPC: C12N1/21
Filed: 1995-04-13
Abstract: Compositions comprising gp350 variant DNA and amino acid sequences are provided, as are vectors and host cells containing such sequences. Also provided is a process for producing homogeneous gp350 protein recombinantly and in the absence of production of gp220 protein, pharmaceutical compositions containing such protein and prophylactic treatments making use of such proteins.
Patent PT-778729-E (PT)
Inventor: LANGLEY JOHN CHARLES MARK
IPC: A01K23/00
Filed: 1995-08-29
Abstract: PCT No. PCT/GB95/02033 Sec. 371 Date Feb. 28, 1997 Sec. 102(e) Date Feb. 28, 1997 PCT Filed Aug. 29, 1995 PCT Pub. No. WO96/07317 PCT Pub. Date Mar. 14, 1996A disposable, substantially lightweight faece collector device having a receptacle support and a handle portion whose light-weight construction is just sufficient for bearing an empty receptacle, but insufficient to bear, in canti-levered support, a faecally loaded receptacle. The device is adapted to be collapsible into a highly compact form, while providing a mechanism for positively and remotely manipulating the empty receptacle into a faeces loading position.
Patent PT-832421-E (PT)
Inventor: KIANI-AZARBAYJANY ESMAIEL
IPC: H05B44/00
Filed: 1996-06-04
Abstract: The method and apparatus of the present invention provides a system wherein light-emitting diodes (LEDs) (162) can be tuned within a given range by selecting their operating drive current in order to obtain a precise wavelength. The present invention further provides a manner in which to calibrate and utilize an LED probe (150), such that the shift in wavelength for a known change in drive current is a known quantity. In general, the principle of wavelength shift for current drive changes for LEDs is utilized in order to allow better calibration and added flexibility in the use of LED sensors, particularly in applications when the precise wavelength is needed in order to obtain accurate measurements. The present invention also provides a system in which it is not necessary to know precise wavelengths of LEDs where precise wavelengths were needed in the past. Finally, the present invention provides a method and apparatus for determining the operating wavelength of a light-emitting element such a light-emitting diode. <IMAGE>
Patent PT-811376-E (PT)
Inventor: CAVAZZA CLAUDIO
IPC: A61P1/00
Filed: 1997-06-03
Abstract: The use of lower alkanoyl L-carnitines is disclosed for preparing pharmaceutical compositions (particularly foams and enemas) for treating chronic inflammatory bowel diseases, in particular ulcerative colitis.
Patent PT-885014-E (PT)
Inventor: GURNY ROBERT
IPC: A61K9/20
Filed: 1997-02-26
Abstract: A pharmaceutical composition for the controlled release of therapeutic agents from carboxylic acid ortho ester polymers contains a pharmaceutically acceptable salt of an acid, which together with the acid R1-COOH liberated from the decomposition of the ortho ester polymer forms a buffer system in a physiologically acceptable pH range.
Patent PT-958128-E (PT)
Inventor: WOOD JOHN
IPC: B29C65/14
Filed: 1997-07-14
Abstract: Method and apparatus for heat-welding two members by applying radiation, such as infra-red radiation, through one of the members to enter layer(s) interposed between the two members. Method relies on inclusions through thickness of the layer(s) to be responsive to said radiation to raise temperature through thickness and promote bonds at inter-faces with surfaces of said members. The bonds are assessed using thermal imaging camera detecting a near visible radiation arising from the layer(s), which radiation is different from infra-red used for heating.
Patent PT-941381-E (PT)
Title: Method for controlling oxygen delignification of pulp
Inventor: BOKSTROEM MONICA
IPC: D21C9/147
Filed: 1997-11-06
Abstract: Methods of controlling oxygen delignification processes are disclosed including providing chemicals for a first oxygen delignification step, conducting the first oxygen delignification step with the chemicals, conducting a second oxygen delignification step at a predetermined temperature to produce a delignified pulp, measuring the final kappa number of the delignified pulp subsequent to the second oxygen delignification step, adjusting the chemicals provided for the first oxygen delignification step based upon the difference between the actual kappa number reduction and the desired kappa number reduction for the pulp, and adjusting the predetermined temperature based on the chemicals provided to the first oxygen delignification step in order to provide the delignified pulp at a final pH of from about 10.5 to about 11.5.
Patent PT-886456-E (PT)
Inventor: ANDREAS MIETLING
IPC: H04R3/00
Filed: 1998-05-02
Abstract: The method involves operating a sound reproduction arrangement with at least one speaker and with at least one amplifier which is connected over a preferably soluble cable connection and/or over a wireless connection to the speaker. The amplifier receives in a first step data describing sound-specific and/or electric parameters of the speaker through a query of the speaker. The amplifier is automatically configured in a second step under consideration of the data or parameters for an operation with the connected speaker. The configuration is preferably undertaken with regard to a transmission characteristic, especially a frequency and/or phase range, and/or with regard to a load capacity.
Patent PT-952951-E (PT)
Inventor: BRAS PHILIPPE LE
IPC: B65D71/28
Filed: 1998-01-15
Abstract: A carton accomodating a plurality of articles, such as bottles, comprising a top (16, 26), a base (12, 30) and a pair of side walls (14, 28) interconnecting said top and base thereby forming a tubular structure, said top being provided with two spaced rows of apertures (54, 56, 58, 60, 62, 64) through which the top portions of said articles protrude and a carrying handle means (18, 20, 22) extending upwardly from said top characterised in that said handle means is located between said two rows of apertures and is off set from a plane disposed midway between said rows of apertures.
Patent PT-1011765-E (PT)
Inventor: KLIPPENSTEIN JOHN
IPC: A61M5/32
Filed: 1998-04-01
Abstract: A pneumatic retractable syringe in which the needle is retracted into the barrel of the syringe following use by compressed gas that is released from a gas reservoir when the gas reservoir is ruptured by applying force to the plunger after injection is completed.
Patent PT-1021404-E (PT)
Inventor: DEZIEL ROBERT
IPC: C07D205/09
Filed: 1998-10-06
Abstract: A compound of formula 1:wherein Y is S or O;R1 is C1-6 alkyl; (C0-6 alkyl)aryl; (C0-6 alkyl)Het; orR1 is an amino acid analog or dipeptide analog of the formula:wherein R2 is H, C1-10 alkyl; or an amide or ester group;A is C6-10 aryl, Het or CH-R3 wherein R3 is C1-6 alkyl or (C0-4 alkyl)aryl; andZ is H, C1-6 alkyl, or an acyl;R4 is hydrogen, lower alkyl, methoxy, ethoxy, or benzyloxy; andR5 is alkyl, cycloalkyl, carboxyl group; an aryl;Het or Het(lower alkyl); or R4 and R5 together with the nitrogen atom to which they are attached form a nitrogen containing ring optionally substituted with phenyl or C(O)OCH2-phenyl, said phenyl ring optionally mono- ordi-substituted with among others C(O)OR7 wherein R7 is lower alkyl or phenyl(lower alkyl); or a therapeutically acceptable acid addition salt thereof which compounds are useful in the treatment of HCMV infections.
Patent PT-1042537-E (PT)
Inventor: GESTERMANN FRITZ
IPC: C25B1/26
Filed: 1998-12-08
Abstract: A method is described for the electrochemical processing of HCL gas to high-purity chlorine in which the process of an HCL gas-phase electrolysis with purified HCL gas from, for example, chemical reactions is coupled to a hydrochloric acid electrolysis with dilute hydrochloric acid, with the use if desired of a consumable oxygen cathode.
Patent PT-970871-E (PT)
Inventor: JEAN BIGO M
IPC: B62B7/06
Filed: 1999-06-14
Abstract: The pushchair has a reclinable hammock seat on a frame with pusher bars (15) that slide relative to front legs (11) when the pushchair is folded. The seat is joined to the frame by two sets of fixings, one of which (21) has adjusting mechanisms for the seat's angle, while the other set (19) co-operates with locking elements which ensure that the hammock is located in its set position each time the frame is unfolded. The locking elements consist of stops on the frame, at least one rod (114) to engage with a rear leg (13), and cams interacting with sliders (115).
Patent PT-1071617-E (PT)
Inventor: BOUGAMONT JEAN-LOUIS
IPC: B65D47/34
Filed: 1999-04-13
Abstract: A dispensing device mountable on a tank having a sheathed pushbutton and movable collar. The collar having a first, temporary, high position on the pushbutton and being held in place frictionally by at least two projection members on the interior face of the collar in contact with the pushbutton. The collar having a second, low position and being held in place by catches cooperating with the neck of the tank.
Patent PT-1102815-E (PT)
Inventor: LUFT WERNER
IPC: C08K3/10
Filed: 1999-07-08
Abstract: The present invention relates to mixtures containing bi-functionally terminated diorganopoly siloxanes aminosilane or oxime or alkoxy crosslinking agents, and optionally, filling materials, suitable additives, pigments, colorants, anti-oxidation pigments, anti-heat pigments, and light-protection pigments in addition to solvents and plasticizers. Said mixtures contain water and a catalyst in the form of an acidic or basic neutral salt as an accelerating cross-linking agent.
Patent SG-14092-G (SG)
Title: Thermo-irreversible aqueous gels
IPC: A23L13/20
Filed: 1992-02-14
Abstract: Thermo-irreversible aq. gels are made by subjecting a gellable combination of xanthan gum and glucomannan gum at a pH above 6 to a heat treatment under temp. and time conditions which cause the gel to become irreversible Pref., the pH is 6-10 (6.5-8). The gel also includes food materials, e.g. meat, fruit or vegetable material. It also includes other gums and/or gelling agents e.g. agar, carrageenan, pectin, alginate, gellan or guar gum. The ratio xanthan gum: glucomannan gum is 5:95-95:5 (1:10-10:1). The two gums total 0.02-6(0.5-4) wt.% w.r.t. gel. The glucomannan is from Amorphophallus corms.
Patent IE-860209-L (IE)
Title: Thieno-triazolo-diazepines
IPC: C07D495/00
Filed: 1986-01-24
Abstract: 1. Thieno-triazolo-1,4-diazepino-2-carboxylic acid amides of general formula   see diagramm : EP0194416,P21,F2   wherein R1 represents hydrogen, a straight-chained or branched alkyl group having 1 to 4 carbon atoms, optionally substituted by halogen or hydroxy, cyclopropyl, alkoxy with 1-3 carbon atoms or halogen ; R2 and R3 , which may be identical or different, represent hydrogen, a straight-chained or branched alkyl or hydroxyalkyl group with 1 to 4 carbon atoms or both groups R2 and R3 together with the nitrogen atom represent a 5-, 6- or 7-membered ring which optionally contains a nitrogen, oxygen or sulphur atom as a further heteroatom, the second nitrogen atom optionally being substituted by an alkyl group with 1-4 carbon atoms ; R4 represents phenyl, wherein the phenyl ring may be mono- or polysubstituted by methyl, halogen, nitro or trifluoromethyl, or alpha-pyridyl and n represents one of the numbers 0, 1, 2, 3, 4, 5, 6, 7 or 8.
Patent IE-790302-L (IE)
Title: Treatment of diptera
IPC: C07D251/70
Filed: 1979-02-16
Abstract: The present invention relates to a procedure for treating domestic animals and productive livestock belonging to the class of Mammalia (mammals) for systemic control of tissue-parasitic insect larvae of the order of Diptera, which comprises parenteral or transcutaneous administration to the animals to be treated of an effective dose of an active substance of the general formula I <IMAGE> (I) in which R1 is hydrogen, methyl, ethyl or cyclopropyl, R2 is hydrogen or methyl, R3 is hydrogen, methyl or cyclopropyl and R4 is hydrogen or methyl, or of an an acid addition salt thereof which is non-toxic to mammals or of a composition which contains the active substance or an acid addition salt thereof which is non-toxic to mammals.
[US4187304A]
Patent IE-880326-L (IE)
Title: Container for contact lenses
IPC: B65D81/00
Filed: 1988-02-05
Abstract: A container for a number of sealed packages for individual contact lenses. The individual lenses are packed in a sealed container in water and must be steam sterilized. Each individual package is stacked in the container of this invention during sterilization and drains are provided in the container for excess water resulting from the sterilization process. When sterilization is completed the container may be closed and sealed. The container has tamper resistant and tamper evident features.
[EP0281255A1]
Patent IE-33067-L (IE)
Title: Coumarin derivatives
IPC: C07H17/075
Filed: 1969-04-28
Abstract: 1,253,286. 3 - Amido - 7 - (pyrrolylcarbonyl) noviosylcoumarins. BRISTOL-MYERS CO. 21 April, 1969 [29 April, 1968], No. 20176/69. Headings C2A and C2C. Novel compounds of the formula (II) where R is H or CH 3 , and X is a group of the formula or -C m H 2m-1 in which n is an integer of 1 to 21, m is an integer of 2 to 21, R<SP>1</SP> and R<SP>2</SP> are alike or different and denote H, cyclohexyl or R<SP>3</SP>, R<SP>4</SP>- substituted-phenyl, R<SP>3</SP> and R<SP>4</SP> being alike or different and denoting H, F, Cl, Br, I, CF 3 , -NH 2 , NO 2 , N,N-di(C 1-8 alkyl)amino, CN, C 1-8 alkyl, C 2-8 alkenyl, C 2-8 alkynyl, C 1-8 alkoxy, -OH, -COOH, -COO-C 1-8 alkyl -OCOCH 3 , -SH, -S-C 1-8 alkyl or -SCOCH 3 , may be obtained (a) by reacting a di, tri or tetratetrahydropyranyl coumermycin A 1 or A 2 with an acylating agent XCOZ, where Z is halogen, -OCOX or -OCOC 1-8 alkyl at a temperature from - 25 to 150 C. in a protonaccepting solvent system to yield an intermediate compound of the formula: which is allowed to stand in a polar solvent with a catalytic amount of an acid at a temperature above 0 C. to cleave the tetrahydropyranyl ether linkage, or (b) by reacting a compound of the formula (IX): with an acylating agent XCOHal in pyridine solution. The preparation of intermediates is described as follows: monosodium coumermycin A 1 is reacted with benzylchloroformate to yield biscarbo-benzoximido-coumermycin A 1 which is treated with HCl to yield 3-carbobenzoxamido-4- hydroxy-8-methyl-7-[3-0-(5-methyl-2-pyrrolylcar - bonyl)-noviosyloxy]coumarin and this is hydrogenolyzed to 3-amino-4-hydroxy-8-methyl-7-[3 0-(5-methyl-2-pyrrolylcarbonyl)noviosyloxy] coumarin (IX). Pharmaceutical compositions effective against diseases caused by Gram-positive and some Gram-negative bacteria comprise compounds of the formula II above together with a diluent or carrier.
[GB1253286A]
Patent IE-780733-L (IE)
Title: Two-bottle package
IPC: B65D71/00
Filed: 1978-04-13
Abstract: A package of and a bag for two bottles. The bag is made from an unsupported and unreinforced thin plastic material that is substantially incapable of safely supporting the weight load of the bottles from a single thickness area of the bag material. In the package the bag has two substantially stretched and tensioned areas. One of the areas is a band about the body portion of the bottles. The other area is a band that includes gathered and secured material, part of which is a handle. The two stretched and tensioned band areas of the bag cooperate together and with the bottles to firmly hold the bottles together and enable the weight load of the bottles to be safely and securely carried from the handle.
[US4099616A]
Patent IE-37785-L (IE)
Title: Automatic system for displaying and exploiting data¹pertaining to vehicles passing predetermined points
IPC: B61L27/00
Filed: 1973-05-24
Abstract: 1438183 Electric selective signalling; roadtraffic signals THOMSON-CSF 24 May 1973 [26 May 1972] 25004/70 Headings G4H and G4Q The invention relates to a system for presenting and utilizing data pertaining to vehicles (e.g. buses) at predetermined transit points along a route defined thereby (e.g. bus stops). At a bus stop, frequency-, phase-, or amplitude-modulated radio signals are received and demodulated 1-3 and passed to series/parallel registers 4 where they are checked for parity. The outputs 5-9 from 4 indicate respectively: message valid, bus identity number, vehicle occupancy, distance Dv from a datum point, e.g. start of route, and direction of travel. Signals 5-7 pass to a storage unit 14, Fig. 3 (not shown), which incorporates appropriate gating circuitry. Signal 8 and a signal Ds (distance of bus stop from start of route) are fed to a subtractor 12 which sends signals 20 (De = Ds - Dv) and 22 (sign of De) to 14. Signal 9 is fed to a comparator 10 to check that it is going in the right direction for the bus stop (output 18). Store 14 is linked via a code converter 15 to a display 16 (luminescent, liquid crystal, &c.) which indicates, inter alia, the distance De of the bus from the bus stop and the number of unoccupied seats thereon. If several routes pass the same bus stop, the system will include separate items 10-16 for each route, the comparators 10 being used to discriminate between the different routes. The system may be adapted to control traffic lights when a bus is within a "zone of action" (distance Da) thereof. At each set of traffic lights, Fig. 5, signals De, Da from subtractor 12 and a store 56 are compared at 55: if De<Da and if De>0, a gate 54 is enabled. This enables a gate 57 which passes the vehicle number 6 to a store 49 if this is empty (determined by logic 48-52) and if the received message is correct in other respects (gate 23 and comparator 50). A signal 53 indicating that 49 is not empty is then used to control the traffic lights. The system may be adapted by suitable duplication of components to deal with several buses within the "zone of action" and/or several routes passing the traffic lights.
[GB1438183A]
Patent IE-35468-L (IE)
Title: Toughened glass sheets
IPC: C03C27/12
Filed: 1971-07-21
Abstract: 1345538 Laminated windscreens TRIPLEX SAFETY GLASS CO Ltd R MELLING and J PICKARD 27 July 1971 [29 July 1970] 36749/70 Heading B5N [Also in Division C1] A laminated glass unit comprises a toughened glass sheet having a heat transfer coefficient in the range 0À008-0À02 cal. cm<SP>-2</SP>, c<SP>-1</SP>, sec<SP>-1</SP> for 1À8 mm. glass to 0À006-0À009 cal. cm<SP>-2</SP>, c<SP>-1</SP>, sec<SP>-1</SP> for 4mm. glass, bonded to a second sheet of glass with an interlayer of plastics material. The second sheet may be toughened to the same extent as the first, The toughened sheet preferably has a central tensile stress of 260-470 kg.cm.<SP>-2</SP> for 1À8 mm. glass to 210-330 kg.cm.<SP>-2</SP> for 4 mm. glass, and the second sheet may have tensile stress less than 70 kg.cm.<SP>-2</SP>. The unit may be a vehicle windscreen, the toughened sheet being the inner sheet of the screen.
[GB1345538A]