baber/WOPTO huggingface dataset:
Patent CA-2240494-C (CA)
Title: Therapeutic molecules generated by trans-splicing
Inventor: MITCHELL LLOYD G
IPC: C07H21/02
Filed: 1996-12-13
Granted: 2007-03-13
Abstract: The molecules and methods of the present invention provide a means for in vi vo production of a therapeutic molecule in a selected subset of cells. The pre-therapeutic molecules of the invention are substrat es for a trans-splicing reaction between the pre-therapeutic molecules and a pre-mRNA which is uniquely expressed in the specific target cells. The in vivo trans-splicing reaction provides an active therapeutic RNA which is functional as RNA or encodes a protein to be expressed in the target cells. The expression product of the mRNA is a protein of therapeutic value to the cell or a toxin which causes killin g of the specific cells.
Patent CA-2243049-C (CA)
Title: Stretchable absorbent articles
Inventor: HINES LETHA MARGIE
IPC: A61F13/15
Filed: 1992-07-23
Granted: 2002-11-12
Abstract: The present invention relates to absorbent articles such as sanitary napkins worn by women. More particularly, the present invention relates to absorbent articles, such as thin sanitary napkins, that are stretchable, especially in the longitudinal direction.
Patent CA-2244576-C (CA)
Inventor: VOLGYESI GEORGE
IPC: A61M15/00
Filed: 1998-08-04
Granted: 2008-02-05
Abstract: An inhalation device for use in delivering a powdered substance to a user, the inhalation device comprises a housing including a holding portion for holding the substance; an air entry passageway sized and configured to direct air entering the inhalation device at the portion and to fluidize the substance upon inhalation by the user; a hold-up chamber in flow communication with the holding portion for receiving the fluidized substance and maintaining the substance in a fluidized state during inhalation by the user; and an air exit passageway in flow communication with the hold-up chamber and adapted to deliver the substance to the user.
Patent CA-2246747-C (CA)
Inventor: RADOMSKY MICHAEL
IPC: A61K47/36
Filed: 1997-03-05
Granted: 2011-01-04
Abstract: L'invention concerne une composition favorisant la croissance osseuse, comprenant un acide hyaluronique et un facteur de croissance. Ladite composition présente une viscosité et une biodégradabilité suffisantes pour persister sur le site sur lequel on désire induire la croissance osseuse, pendant suffisamment de temps pour favoriser la croissance osseuse, On utilise de préférence de l'acide hyaluronique dans la composition, à raison de 0,1 à 4 % en poids, et le facteur de croissance préféré est bFGF, en concentration d'environ 10?-6¿ à 100 mg/ml.
Patent CA-2246980-C (CA)
Title: High light transmission, low-e sputter-coated layer systems and insulated glass units made therefrom
Inventor: LINGLE PHILIP J
IPC: C03C17/36
Filed: 1998-09-14
Granted: 2002-08-20
Abstract: A high visible light transmitting, low-E sputter coating system, achieving neutral color and non-mirror-like appearance, useful in 2-pane and 3-pane IG units is achieved by an intermediate layer of silver, an undercoat of a metal oxide or nitride having an index of refraction of 2.35-2.75 and an overcoat of a metal oxide or nitride having an index of refraction of 1.85-2.25.
Patent CA-2248282-C (CA)
Inventor: CESARONI ANTHONY JOSEPH
IPC: F42B12/74
Filed: 1997-04-03
Granted: 2003-01-28
Abstract: A bullet that will retain markings from a firearm barrel when fired from such firearm. The bullet comprises a right cylindrical core with opposed ends, one such opposed end having a tapered section integrally connected thereto. The core is formed from a lead-free composition of a polymer and filler and selectively retains its integrity when fired from the firearm or is frangible.  The right cylindrical core has a jacket that is cylindrical and formed from a thermoplastic polymer or copper. The thermoplastic polymer has a softening point above firearm barrel temperatures.
Patent CA-2251061-C (CA)
Title: Power transmitting system in four-wheel drive vehicle
Inventor: KUROKAWA TAKUYA
IPC: F16H39/40
Filed: 1998-10-21
Granted: 2002-12-03
Abstract: A hydraulic coupling device includes left and right vane pumps which discharge working oil in response to the relative rotation of main driven wheels and left and right subsidiary driven wheels. First orifices are defined in a side plate disposed between the left and right vane pumps to permit communication between intake ports and discharge ports in the vane pumps. Orifices are defined in the side plate to permit communication between the intake ports and between the discharge ports in the vane pumps. With the above arrangement, in a hydraulic coupling device of a power transmitting system in a four-wheel drive vehicle, the formation of the orifices can be easily carried out, and the characteristics of the orifices can be stabilized.
Patent CA-2254615-C (CA)
Inventor: ITO TAKAYUKI
IPC: G06T7/00
Filed: 1998-11-30
Granted: 2008-05-27
Abstract: A device is provided which detects image patterns which may cause photosensitive attacks, based on the contrast intensity and values of frequency bands having a peak value. A frame image constituting video is image analyzed for contrast intensity and spatial frequency, in the contrast detector and the peak seeker respectively.
Patent CA-2268969-C (CA)
Inventor: RASANEN JUHA
IPC: H04Q7/22
Filed: 1997-10-17
Granted: 2007-01-02
Abstract: The invention relates to a mobile system in which the radio interface rate of a traffic channel and the intermediate rate of a transmission channel restrict the number of bits available for the transmission of terminal interface statuses (S), network independent clocking (N) and subchannel numbering (#) of a multichannel data link. In the invention the bits form a subframe (n, ..., n+10), and the status and control information are multiplexed inside successive subframes in a superframe structure (SUPERFRAME). In other words, the capacity of the bits available for the control information is shared by various kinds of control information by means of the superframe structure.
Patent CA-2270178-C (CA)
Inventor: LOCARNINI STEPHEN ALISTER
IPC: C12N15/54
Filed: 1997-08-15
Granted: 2012-06-12
Abstract: The present invention relates generally to viral variants exhibiting reduced sensitivity to particular agents and/or reduced interactivity with immunological reagents. More particularly, the present invention is directed to hepatitis B variants exhibiting complete or partial resistance to nucleoside analogues and/or reduced interactivity with antibodies to viral surface components. The present invention further contemplates assays for detecting such viral variants which assays are useful in monitoring anti-viral therapeutic regimes.
Patent CA-2278271-C (CA)
Inventor: HUDGIN GLEN
IPC: G01F23/40
Filed: 1999-07-21
Granted: 2009-11-03
Abstract: A sludge gauge for measuring the depth of a sludge layer covering a bottom of a septic tank. The sludge gauge has a guide sleeve mountable through a septic tank cover and a probe, at least an upper end of which is slidably received in the guide sleeve. The probe has a base end distal an upper end. The density and base end configuration of the probe are selected to cause the probe to sink through a liquid layer in the septic tank until the base end settles on the sludge layer when the probe is released from a raised position. A cap is securable over an upper end of the guide sleeve and a collapsible connector extends between the cap and the probe for raising the probe into the raised position. An indicator is attached to the cap for indicating a height of the base end of the probe above the bottom of the septic tank thereby indicating sludge depth in the tank.
Patent CA-2278553-C (CA)
Inventor: LORENZ KLAUS
IPC: C07D417/12
Filed: 1998-01-10
Granted: 2009-05-12
Abstract: L'invention concerne des composés de la formule (I) et leurs sels s'utilisant comme herbicides et régulateurs de croissance végétale, (I), formule dans laquelle R<1> à R<9>, W et A ont la signification mentionnée dans la revendication 1. Ces composés peuvent être obtenus d'après des procédés tels qu'ils figurent dans la revendication 5, au moyen de produits intermédiaires, en partie nouveaux, selon la revendication 9.
Patent CA-2279499-C (CA)
Title: Dispositif pour l'application d'un produit de maquillage comportant une brosse, procede de fabrication et applicateur
Inventor: GUERET JEAN-LOUIS
IPC: A46B9/02
Filed: 1999-08-02
Granted: 2006-07-11
Abstract: Dispositif pour l'application d'un produit, notamment un produit cosmétiq ue tel que du mascara, comportant un récipient (3) contenant une réserve de produit et un applicateur (2) ayant un axe (X), pourvu selon cet axe (X) à une extrémité d'un élément de préhension (4) et à l'autre extrémité d'un élément d'application (5), l'élément de préhension et l'élément d'application étant reliés par un élément de liaison (6). L'élément d'application comprend une brosse du type goupillon dont l'âm e s'étend dans une direction non parallèle à l'axe (X) de l'applicateur et par le fait que l'élément de liaison (6) et la brosse sont conformés de telle sorte que les poils s'étendant depuis l'élément de liaison (6) pour servir à l'application du produit soien t contenus dans un secteur d'étendue angulaire inférieure ou égale à 180.degree. autour de ladite âme.
Patent CA-2281685-C (CA)
Title: Process for making maleic anhydride polymers which include maleamic acid and/or its cyclic imide repeat units
Inventor: KATIRGIS JOHN A
IPC: C08F8/14
Filed: 1998-03-04
Granted: 2008-10-28
Abstract: A process for making derivatized polymers of maleic anhydride containing maleamic acid and its corresponding cyclic imide repeat units, in alcohol solution, at a temperature of about 60-160 .degree.C, duri ng a reaction period of about 1-25 hours. The product is a polymer having a predetermined ratio of the above repeat units.
Patent CA-2281920-C (CA)
Title: Compositions and methods for modulating cellular nf-.kappa.b activation
Inventor: MANNING ANTHONY
IPC: C12N1/19
Filed: 1998-02-18
Granted: 2010-05-04
Abstract: Compositions and methods for modulating the activation of nuclear factor .kappa.B (NF-.kappa.B) are provided. The compositions comprise one or more agents that modulate ubiquitination of phosphorylated I.kappa.B.alpha. and/or I.kappa.B.beta.. Such compositions may be used for treating diseases associated with NF-.kappa.B activation. Modulating agents include peptides that comprise a recognition domain for E3 ubiquitin ligase.
Patent CA-2282118-C (CA)
Inventor: FRAPPIER JOHN P
IPC: A43D3/00
Filed: 1999-09-14
Granted: 2004-07-13
Abstract: A footwear customization system that includes a rearfoot and forefoot goniometer for measuring rearfoot and forefoot alignment of a foot to provide rearfoot and forefoot alignment data. A customizable piece of footwear having a moldable, settable midsole is mounted on a shoe press, and the shoe press applies pressure to the midsole based on the rearfoot and forefoot alignment data in order to form a contour in the midsole. The contour provides alignment corrections based on the rearfoot and forefoot alignment data. A computer running a footwear customization program can be interfaced to the rearfoot and forefoot goniometer and the shoe press to receive the rearfoot and forefoot alignment data from the rearfoot and forefoot goniometer and provide it to the shoe press. An injection apparatus can be used to set the midsole of the piece of footwear so that the midsole retains the contour after the piece of footwear has been removed from the shoe press. Preferably, the rearfoot and forefoot alignment of the foot is measured while the foot is in a non-weight bearing position known as sub-talar neutral.
Patent CA-2292134-C (CA)
Inventor: ZELINSKI THOMAS W
IPC: B31B50/59
Filed: 1999-12-08
Granted: 2008-06-17
Abstract: A pressing apparatus for producing a food service paperboard container from a paperboard blank so that the paperboard container possesses an overturned rim provided with folds includes a first die and a second die that are movable relative to one another. The first die includes a first base and a first platform that is movable with respect to the first base, with the first base having a curved surface for engaging the outer periphery of the paperboard blank. The second die is positioned in opposing relation to the first die and includes a second base and a second platform that is movable with respect to the second base. The second die is movable with respect to the first die and the second base has a curved surface for engaging the outer periphery of the paperboard blank so that the outer periphery of the paperboard blank is pressed between the curved surface of the first base and the curved surface of the second base. A first cast-in heater is mounted within a recess in the first die and includes a resistor wire embedded within a thermally conductive cast-in material. A second cast-in heater is mounted within a recess in the second die and includes a resistor wire embedded within a thermally conductive cast-in material.
Patent CA-2298209-C (CA)
Inventor: MANNINEN TAISTO
IPC: A63C11/22
Filed: 2000-02-08
Granted: 2008-01-15
Abstract: The object of the invention is a pole provided with a quick-releasing interchangeable lateral support extension, especially a walking, skiing, alpine skiing or other sports pole. Around the lower end of the pole (1) is injection moulded a sleeve socket (2) from which a guide projection (3) and a locking projection (4) protrude. The lateral support extension sleeve (6, 8) comprises a resilient tongue (12), below which there is a receiving aperture (14) for the locking projection (4). The sleeve also comprises a guide groove (11) for receiving the guide projection (3). The lateral support extension (5) is easy to detach by turning the resilient tongue (12) outwards.
Patent CA-2298856-C (CA)
Title: Living tissue equivalents
Inventor: MASON VALERIE
IPC: G01N33/50
Filed: 1990-08-24
Granted: 2004-11-16
Abstract: The present invention provides an apparatus for determining the interaction of tissue and at least one agent by use of at least one tissue equivalent, the apparatus comprising a first and a second region defined by a permeable means provided with a collagen gel on which the tissue equivalent is disposed, whereby the tissue equivalent defines the first region and the permeable member defines the second region.
Patent CA-2310893-C (CA)
Inventor: DOBRAN MAURO F
IPC: E21B7/02
Filed: 2000-06-05
Granted: 2005-05-24
Abstract: Apparatus for blast hole drilling includes a hammer and drill bit driven by a hydraulic drive motor outside the hole through a drill string extending along the drilled hole to the drill bit. The drive motor is carried on a mast with a telescopic hydraulic cylinder driving the motor along the mast in a forward direction for forwarding the drill bit along the hole to the rock face and for applying a feed force on the drill bit at the rock face and in a rearward direction for reducing the feed force and for withdrawing the drill bit from the hole. The cylinder assembly has a pulldown pressure side fed at a constant supply rate and a holdback pressure side controlled to discharge the fluid when moving downwards and to supply the fluid at a constant rate when pulling up. The control system includes a first valve for controlling a rate of supply of fluid to the motor for controlling the rate of rotation of the drill bit, a drilling valve operable to supply fluid to the pulldown side or to the holdback side, a second valve for controlling the rate of supply of fluid to the pulldown side, a third valve for controlling the rate of discharge of fluid from the holdback side, a hydraulic feedback line for communicating an increase in pressure of the fluid at the motor, caused by an increase in resistance to the rotation of the drill bit, to the holdback side of the so that the rate of forward movement of the drill bit is varied in proportion to changes in the pressure at the motor and a pressure switch responsive to pressure of the fluid at the hydraulic drive assembly exceeding a predetermined pressure limit to repeatedly cycle an upward and downward movement of the drill bit until the overpressure condition clears or until a number of cycles is completed.
Patent CA-2315818-C (CA)
Title: Water-soluble eye drop
Inventor: SUGAHARA YUJI
IPC: A61P27/02
Filed: 1998-12-16
Granted: 2005-10-11
Abstract: Disclosed is a water-soluble eye drop comprising (a) at least one selected form carteolol and an acid addition salt thereof, (b) at least one acrylic polymer selected from a straight-chain type polyacrylic ac id and a pharmaceutically acceptable water-soluble salt thereof, and (c) at least one selected from a water-soluble alkali metal salt and a water-soluble amine. The water-soluble eye drop of the present invention has a remarkably long duration time of drug efficacy, and is superior in intraocular pressure inhibition action and is effective for treatment of glaucoma.
Patent CA-2319272-C (CA)
Inventor: BERTHELON JEAN-JACQUES
IPC: A61K31/185
Filed: 1998-01-27
Granted: 2005-11-08
Abstract: The invention relates to new derivatives of sulfonic, phosphonic or phosphinic aminoalkane acids, corresponding to formula (I), where X is selected from among (a), (b), (c) and (d), where R is a C1-C7 alkyl radical, R1, R2 and R3 are selected from hydrogen and a C1-C7 alkyl radical, and A is a group of formula (e) where v and w are 0, 1, 2 or a group of formula (f) where R5 and R6 are selected independently of each other from hydrogen, a C1-C7 alkyl radical, an aryl radical having between 6 and 14 carbon atoms and a heteroaryl radical; t is 1-3; R4 is selected from hydrogen, a C1-C7 alkyl radical, a CF3 radical, an aryl radical having between 6 and 14 carbon atoms and a heteroaryl radical; M is a monovalent metal (Na, K, Li) or divalent metal (Ca, Mg, Sr, Zn); m is 1 or 2; p is 1-2 and q is 1-2; and where p and q are such that the electrical neutrality of the salt is ensured. The above components can be used for the treatment of alcohol dependence.
Patent CA-2332465-C (CA)
Inventor: SANDIDGE JERE T
IPC: H04M11/00
Filed: 1999-05-20
Granted: 2007-12-04
Abstract: Expanding the data carrying capacity of a forward control channel of a cellular mobile radiotelephone (CMR) system.  By utilizing data fields that would otherwise be unused in a conventional data message system, an operation identifier can be transmitted to a data reporting device. The forward control channel carries control messages which are capable of causing cellular devices to perform certain communications functions.  An Order Code data field within the control message defines the functionality of the message. By utilizing the Order Code data fields to invoke the message waiting functionality of the control message, and replacing the message waiting data with an operation identifier, the data carrying capacity of the forward control channel is increased. An external device connected to the data reporting device can be caused to perform an operation defined by the operation identifier. The operation identifier can define an operation specified from a list of available operations.  For cellular communications devices that are responsive to more than one mobile identification number (MIN), the range of operations that can be processed by a control unit is greatly expanded.
Patent CA-2334226-C (CA)
Title: Tissue opening locator
Inventor: ZHU YONG HUA
IPC: A61B17/128
Filed: 1999-06-04
Granted: 2005-04-05
Abstract: A system which facilitates the closure of puncture wounds in the vasculatu re of a patient by helping locate and isolate the site of the puncture wound in the patient. A tube or catheter having an indicator hole for aspirating blood assists in locating the site of the wound and positioning a retractor adjacent the wound. The retractor moves tissue surrounding the wound laterally to form an access path to the wound. The retractor and catheter are used with a tissue therapy device such as a wound closure device.
Patent CA-2335838-C (CA)
Title: Instruments d'insertion de clou centromedullaire
Inventor: RUSSELL THOMAS ANTHONY
IPC: A61B17/17
Filed: 1999-06-30
Granted: 2008-06-03
Abstract: L'ensemble comprend une gaine (12), un boîtier (14) et un alésoir interne (16).  La gaine est une gaine creuse allongée de forme cylindrique comportant des extrémités proximale et distale, l'extrémité distale comportant une pluralité de lames de coupe. Le boîtier est fixé à la gaine et de forme globalement cylindrique, il présente une partie supérieure, une partie inférieure et un trou traversant. La partie supérieure est pourvue d'un mécanisme de verrouillage libérable qui sert à bloquer l'alésoir interne à l'intérieur du boîtier. L'alésoir interne comprend un corps du type canule allongée ainsi que des extrémités proximale et distale. L'extrémité distale comporte une tête d'alésage rotative alors que l'extrémité proximale comporte un axe de foret et un dispositif de couplage servant à le coupler à un foret. Une partie du corps comporte un collier annulaire (158) doté d'une partie saillante (160) qui vient se loger dans une encoche (94) prévue dans le boîtier. L'alésoir est dimensionné et formé de manière à pouvoir être introduit dans l'alésage du boîtier et de la gaine. L'ensemble d'alésage est configuré pour créer une ouverture d'entrée à l'intérieur du canal d'un os et pour former un canal de travail dans lequel sont introduits plusieurs alésoirs de tailles graduées pour aléser progressivement le canal d'un os.
Patent CA-2339236-C (CA)
Inventor: HORESH NADAV
IPC: G01N21/25
Filed: 1999-08-25
Granted: 2006-05-30
Abstract: A method of analyzing particles for chemical or biological species. Spectr al images of the particles are acquired (24, 46). Targets are identified in the images and are classified (52, 80) according to morphology type (78) and spectrum type (76). A descriptor vector (58, 88) is formed and transformed to a vector of mass concentrations of chemical species of interest, or of number concentrations of biological species of interest, using a relationship determined in a calibration procedure. In the calibration procedure, spectral images of calibration samples of known composition are acquired, and empirical morphology types and spectrum types are inferred from the spectral images. Targets are identified in the spectral images and classified according to morphology type and spectrum type. A calibration descriptor vector (58, 88) and a calibration concentration vector (60, 90) i s formed. A collection relationship (94) between the calibration descriptor vectors an d the calibration concentration vectors is found, either by multivariate analysis or by training a neural network.
Patent CA-2342822-C (CA)
Inventor: BAILEY DUNN M
IPC: F25J1/02
Filed: 1999-10-18
Granted: 2004-01-13
Abstract: The inventive process and associated apparatus are ideally suited for methodology and apparatus for the small-scale liquefaction of natural gas. The current invention provides a methodology and apparatus for the liquefaction of normally gaseous material, most notably natural gas, which reduces both the number of process vessels (34, 58) required and also the associated space requirements over convention apparatus while resulting in only a slight decrease in process efficiency.
Patent CA-2350607-C (CA)
Inventor: SEMAN LEO
IPC: G01N33/68
Filed: 1999-11-12
Granted: 2009-04-07
Abstract: The invention relates to a method for determining homocysteine concentration in samples in which homocysteine is condensed using an enzyme cystathionine .beta. synthase to form cystathionine. Pyruvate and/or ammonia are released from cystathionine by action of an enzyme, cystathionine .beta. lyase, and homocysteine is regenerated. The release of pyruvate and/or ammonia can be correlated to the concentration of homocysteine present in the sample.