Patent SG-11201807300P-A (SG)
Title: Uterine cancer treatments
Inventor: MAHR ANDREA
IPC: C12N5/0783
Filed: 2017-03-02
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 14 September 2017 (14.09.2017) WIPO I PCT (10) International Publication Number WO 2017/153247 Al 11111111111111011101111111111101011111011101111011011101011101111111111111110111111 (51) International Patent Classification: A61K 38/17 (2006.01) CO7K 7/06 (2006.01) A61K 39/00 (2006.01) C12N 5/0783 (2010.01) (21) International Application Number: PCT/EP2017/054908 (22) International Filing Date: 2 March 2017 (02.03.2017) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 1603987.7 8 March 2016 (08.03.2016) GB 62/305,222 8 March 2016 (08.03.2016) US (71) Applicant: IMMATICS BIOTECHNOLOGIES GMBH [DE/DE]; Paul-Ehrlich-StraBe 15, 72076 Tiibingen (DE). (72) Inventors: MAHR, Andrea; Kirschenweg 22, 72076 Tiibingen (DE). WEINSCHENK, Toni; Im Morgenrain 15, 73773 Aichwald (DE). SONG, Colette; Wil- li-Baumeister-Weg 21, 73760 Ostfildern (DE). SCHOOR, Oliver; Eichhaldenstrasse 19, 72074 Tiibingen (DE). FRITSCHE, Jens; Larchenweg 11, 72144 Dusslingen (DE). SINGH, Harpreet; 2215 Dryden Rd, Houston, Texas 77030 (US). (74) Agent: BOEHMERT & BOEHMERT; Krauss, Jan, Pettenkoferstrasse 22, 80336 Munich (DE). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: with international search report (Art. 21(3)) with sequence listing part of description (Rule 5.2(a)) W O 20 17 / 15 3 247 Al (54) Title: UTERINE CANCER TREATMENTS (57) : The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor- associ- ated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active phar- maceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.