baber/WOPTO huggingface dataset:
Patent GB-2494679-A (GB)
Title: Treatment of neuropathic pain and nerve injury by Nox4 inhibition
Inventor: SCHMIDTKO ACHIM
IPC: A61K31/7088
Filed: 2011-09-15
Abstract: A method for the identification of agents suitable for the prevention or treatment of nerve injury, and in particular for the treatment of pain, especially neuropathic pain, comprises determining the ability of the agent to modulate the activity or expression of NADPH-Oxidase 4 (Nox4) in a biological sample. The invention also relates to inhibitors of the expression and/or the function of Nox4 for use in the prevention and/or treatment of nerve injury, in particular pain, more particularly neuropathic pain, and pharmaceutical composition comprising such inhibitors. The Nox4 inhibitors may also be used for the prevention and/or treatment of nerve injury associated with dysmyelination. The dysmyelination may be associated with leukodystrophies (such as Pelizaeus-Merzbacher disease, Canavan disease or phenylketonuria), schizophrenia, or multiple sclerosis. Alternatively, the injury or pain may be associated with Guillain-Barre syndrome, Charcot-Marie tooth type 1 disease, or multiple sclerosis. The inhibitor may be, for example, an antisense or siRNA molecule against Nox4.
Patent GB-2487274-A (GB)
Title: Wellbore test space creation system
Inventor: TUNGET BRUCE ARNOLD
IPC: E21B29/00
Filed: 2011-12-16
Abstract: System and method of well space provision comprising well apparatus and uncemented bore debris. An untested or unproven apparatus is used to create a void by cutting through concentric tubing in a borehole. The debris 91 from the opening is compressed in a lower portion of the borehole and a settable material placed over the debris to provide a geological equivalent base. Emprical, in-situ measurements are then collated for the unproven apparatus to enable it to be classified as proven.
Patent GB-2490191-A (GB)
Title: Noise covariance estimation wherein initial estimates from multiple channels are selectively combined into a final estimate dependent upon a metric
Inventor: HEIKKILA MARKKU JOHANNES
IPC: H04B1/10
Filed: 2012-01-23
Abstract: An initial/intermediate/raw inter antenna NOise/interference Covariance matrix Estimate (NOCE) is calculated (eg. from received noise vectors) in a multi antenna receiver for each of a plurality of (sub)channels. Metrics are derived from raw NOCEs of first and second channels (eg. LLR or distance metrics indicating how well second channel NOCE predicts first channel noise). If the metric meets a threshold/criterion a final/refined first channel NOCE is derived from the raw first and second channel NOCEs, otherwise the raw first channel NOCE is used as the final NOCE. Channels may be TDMA time slots, OFDM sub-carriers or resource elements or similar. The process may be repeated with multiple second channels for each first channel. Second channels are preferably selected to be close to the first channel in time/frequency/etc. as appropriate. The NOCE may be used in interference rejection combining (IRC). The invention is more responsive to sudden local interference changes than prior art fixed filters/weightings applied to NOCEs.
Patent GB-2485732-A (GB)
Title: Container marker scheme for reducing write amplification in solid state devices
Inventor: ELEFTHERIOU EVANGELOS
IPC: G11C16/34
Filed: 2010-09-14
Abstract: A solid state storage device (300) and method are provided. Multiple blocks (310, 315) are configured as storage memory for a solid state storage device (300), and each block includes multiple pages. A controller (305) is configured to operate the solid state storage device (300). A free block (310) of the multiple blocks is assigned a marker level by the controller (305). For a particular page of the multiple pages, each particular page of data is written to a block (300) of the multiple blocks with a marker level corresponding to a level of dynamicity calculated by the controller (305) for that particular page.
Patent GB-2500946-A (GB)
Title: Folding camper having a height adjustable frame
Inventor: HARRISON JONATHAN M
IPC: B60P3/34
Filed: 2012-07-20
Abstract: A folding camper 10 comprises a trailer 12 mounted on wheels 14 and includes a tow bar coupling 16 in order to secure the folding camper to a towing vehicle. Trailer 12 comprises a rigid box 18 with four rigid side walls 90, 91, 92, 93. Trailer 12 also comprises a rigid cover comprising a first section 22 and a second section 24. The rigid front section 22 is pivotally connected to a wall of the box 18 of the trailer 12. Section 24 is similarly connected to the box 18 of the trailer 12. The folding camper 10 is arranged to be assembled by first pivoting the front cover section 22 which pulls a canopy 30 and rotates a front frame (34, Figure 4). The rear cover section 24 is then pivotally opened which pulls the canopy 30 and rotates a second frame (36, Figure 4). Finally, the height of the first frame (34) is increased in order to put the canopy 30 in tension and to make the canopy 30 taut. Two permanently mounted frames (34, 36) which pivotally move into position and maintain the interior of the folding camper 10 in a sheltered state.
Patent GB-2495359-A (GB)
Title: Computer instructions indicating last-use for deactivating architectural registers
Inventor: SALAPURA VALENTINA
IPC: G06F9/30
Filed: 2012-07-26
Abstract: An ISA includes instructions for selectively indicating last-use of architected operands, such as a register or cache lines, having values that will not be accessed again. The instruction may be an operand deactivating instruction including an opcode field indicating a function to be performed 503 on an associated operand and an indication 501 of the last-use of that operand. Alternatively a prefix (or suffix) instruction indicating last-use of an operand in an associated instruction may be provided. The instruction(s) are executed 500, 506, a determination of last use is made 502, the function performed using the operand 503 before the operand is deactivated such as by setting a tag 507 for the operand 509 in register mapper 508 to a deactivate state and returning 505 the physical register to a free register pool 510. Reading a deactivated operand may return a default value; writing to a deactivated operand may activate the operand assigning a physical register from the pool.
Patent GB-2506365-A (GB)
Title: Vehicle incident detection using an accelerometer and vibration sensor
Inventor: GILBERT WAYNE
IPC: B60R21/0132
Filed: 2012-09-26
Abstract: A vehicle incident detection system (100) comprises a vibration sensor (104) connected to a structural component of the vehicle and an accelerometer (102) mounted on a vehicle and each connected to a signal processing module (101). In use, if the signal processing module detects a first signal above a threshold from the vibration sensor the system stores data from the vibration sensor, the accelerometer and status of the vehicle in a memory (106). Information maybe wirelessly transmitted to a remote sensor on detection of an incident by a wireless transmitter (111). The unit may be battery powered (108). The vibration sensor may be a piezoelectric sensor. The current status of the vehicle may include the speed, engine speed and systematic background noise. The incident may be a collision.
Patent GB-2506438-A (GB)
Title: Outlet for aerosol distribution range of nebulisers or atomisers
Inventor: SINGLETON IAN
IPC: B05B7/00
Filed: 2012-09-29
Abstract: The device increases the range that aerosols are broadcast from nebulisers without interfering with the aerosol generation process. The device generates an independent carrier airflow underneath the nebuliser aerosol output port. Air is drawn into the two separate channels 2, 2 of a conduit which is of greater cross sectional area at one end (the base) than the other (the top) by independently controllable fans 5, 5. Air drawn in at the base is forced to the top where the two channels merge just behind a hooded outlet. By controlling the relative airflows in the two channels turbulence and pulsing may be induced in the expelled carrier airstream which is directed on an upwards trajectory. This independent carrier airflow passes through the generated aerosol and carries it much further from the nebuliser than without the device.
Patent GB-2507479-A (GB)
Title: Smoking article
Inventor: FAWCUS PHILIP
IPC: A24D1/02
Filed: 2012-10-05
Abstract: A smoking article 100 comprises one or more rod articles 110, 111 and an inner layer 113 extending around the rod articles. An outer layer 125 extends around the inner layer and the inner and outer layers are formed by a composite sheet of material 213, 225 wrapped around the rod articles. At least a part of the outer layer is configured to be movable relative to the inner layer. Preferably the inner layer 113 and the outer layer 125 each include a separation line 136,138. An indexing mechanism may be attached to an inner surface of the inner layer. Also disclosed is a blank for wrapping around one or more rod articles to form the smoking article and a method of manufacturing the smoking article. Advantageously the relative movement between the inner and outer layers controls a property of the smoking article, such as an amount of ventilation or a limit on the amount of rotation or movement between the inner and outer layers.
Patent GB-2494571-A (GB)
Title: Shrouded helical pump or turbine
Inventor: URCH MICHAEL JOHN
IPC: F03B17/06
Filed: 2008-11-14
Abstract: A propeller, pump or turbine comprises an elongate helical blade 44 attached to a shroud 50 which rotates with the blade. The blade may be mounted on a shaft 24 which may be held by one or more bearings and may be attached to a motor or generator 30. The blade assembly 14 has a head end 16 and a tail end 18. The shroud may converge towards an intermediate section creating a venturi, and the head 16 and tail 18 ends may be flared in a bell mouth fashion. The tail end may have substantially circumferential or helical slots 108 which permit fluid to be entrained into the flow in the tail section. The blade may comprise a plurality of beams 22 which may be adjustable to vary the pitch of the blade (figure 6).
Patent GB-2499318-A (GB)
Title: Interface Engineering to Optimize Metal III-V contacts in FET devices
Inventor: ZHANG ZHEN
IPC: H01L21/18
Filed: 2013-02-05
Abstract: Techniques for fabricating self-aligned contacts in III-V FET devices are provided. A method for fabricating a self-aligned contact to III-V materials includes the steps of depositing at least one metal on a surface of a III-V material 102, the metal is reacted with an upper portion of the III-V material to form a metal     III-V alloy layer 106 which is the self-aligned contact, an etch is used to remove any unreacted portions of the metal, at least one impurity is implanted into the metal     III-V alloy layer, the impurity implanted into the metal     III-V alloy layer is diffused to an interface between the metal     III-V alloy layer and the III-V material to reduce the contact resistance of the self-aligned contact. The reaction may involve an annealing step.
Patent GB-2513394-A (GB)
Title: Control system, vehicle and method
Inventor: SUFFIELD IAIN
IPC: H02J7/00
Filed: 2013-04-26
Abstract: An apparatus for a vehicle 100 driven by an electric motor 123, powered by an energy storage means 150, generates an audible sound dependent on whether the vehicle 100 is connected to a charging facility 160. The vehicle 100 may be an electric vehicle or a hybrid electric vehicle. The sound or sonic signature may be generated upon detecting or receiving a signal from a portable user identification device 190, such as an electronic key. The sound may be generated inside or outside the vehicle 100 cabin. A plurality of different sounds may be selected, according to a state of charge of the vehicle 100, or whether the vehicle 100 is connected to the charging station 160. A vehicle 100 comprising the apparatus and a method of providing feedback to a vehicle user by generating a sound in this way are also presented.
Patent GB-2513612-A (GB)
Title: Control system, vehicle and method
Inventor: HOLLOWAY KATY
IPC: B60Q5/00
Filed: 2013-05-01
Abstract: An apparatus 145, 15S for a vehicle 100 having an electric propulsion motor 123 and energy storage means 150 for powering the motor. The apparatus 145, 145S is operable to generate an audible sound wherein at least one characteristic of the sound is dependent on an amount of energy stored in the energy storage means 150.
Patent GB-2515490-A (GB)
Title: An aperture array substrate device, a detection system and a method for detecting analytes in a sample
Inventor: O'DRISCOLL STEPHEN
IPC: G01N21/75
Filed: 2013-06-24
Abstract: An optical detection system 100 comprises a photodetector 110 and a substrate120. The substrate comprises an aperture array 121 wherein light 171 is transmittable to the photodetector via the apertures of the substrate only. The apertures are functionalised to provide capture of a target analyte 155 in a sample 150 at an aperture such that capture of an analyte at an aperture causes attenuation of light 123 at said aperture. The photodetector is configured to detect the analyte capture by detecting attenuation of light at an aperture. The detector may be a CMOS CCD sensor. A binary change in the optical signal is detectable.
Patent GB-2505560-A (GB)
Title: Insulated glass blind assembly
Inventor: OUZTS ALLEN CHRISTOPHER
IPC: E06B9/264
Filed: 2011-12-21
Abstract: An insulated glass assembly providing a simple and effective construction for installing a modular assembly inside the insulated glass assembly. The insulated glass assembly may include a spacer frame configured to support the modular assembly, such as a modular blind or shade assembly. The modular assembly may include a head rail module and a control operator module that may be captured by the spacer frame. For example, the spacer frame may capture the head rail module near the upper portion or the lower portion of the insulated glass blind assembly, and may capture the control operator module on a side adjacent to the head rail module.
Patent GB-2506015-A (GB)
Title: Mobile Electrical Power Module
Inventor: JONES DANNY
IPC: H02J3/32
Filed: 2013-08-30
Abstract: An electrical power module 11 configured as a reserve power supply for self-contained, standalone operation or in conjunction with external energy sources. The module comprises an internal battery or cell cluster 12, separate AC and DC charging and delivery circuits, an inverter and bi-directional power converter 14 between the input and output circuits and a control circuit for automatically managing the draw and allocation of power resources according to variable supply and demand. The module can trigger the activation of external energy sources, such as an internal combustion generator 17 or photovoltaic array 15, according to demand and can be connected to a mains grid when available for charging the internal battery 12 and for distribution to loads. The module can further learn power supply and consumption patterns.
Patent GB-2517989-A (GB)
Title: Vehicle seating
Inventor: BEAVEN MATT
IPC: B60N2/30
Filed: 2013-09-09
Abstract: A vehicle seat, for use at the rear of a vehicle to provide rear-facing temporary exterior seating, for example when stationary at a sporting event, comprises a seat surface 1 and is pivotably moveable between a stowed position, where the seat surface is on or within a load floor 3 of the vehicle, and a deployed position where seat surface 1 is pivoted up and out of load floor 3 to overlap or extend beyond a rearmost edge of the vehicle. Most preferably, the pivot comprises a supporting enclosure 2 within or beneath load floor 3 and first and second support legs 10, 20 pivotally connected to the seating surface underside and to the supporting structure, with the first leg having a rear-facing support surface 13 between the pivots, and the second leg having a forward-facing engaging member 23 between the pivots that when deployed engages support surface 13 to provide load-bearing support for seat surface 1. The seat is particularly suitable for vehicles with upward-opening and side-opening tailgates.
Patent GB-2519128-A (GB)
Title: Padlock
Inventor: LITTLE SIMON
IPC: E05B67/00
Filed: 2013-10-10
Abstract: A combination lock, preferably a padlock 10, wherein the combination arrays (dials, rings) 40a-e display a combination of letters and numbers, preferably more than one letter/number and most preferably the date, e.g. 01 JAN 14. Also claimed is a combination lock wherein the arrays define different number of code component options, e.g. the first array has four options, the second ten options etc. A key lock may be provided to override the combination lock. When recoding the combination, a code set indicator may be exposed 90, the indicator displaying an image, symbol or word, e.g. SET. The indicator may be cylindrical and may extend out of the body of the lock. A method of recoding is defined such that when the lock is in the open condition the locking member, i.e. the shackle, is rotated preferably 90Â° or 180Â° (as per Fig 7), the locking member is then depressed and further rotated whilst depressed. This allows the locking arrangement of the arrays to be changed.
Patent GB-2504241-A (GB)
Title: Droplet based assay system
Inventor: COLSTON BILLY WAYNE JR
IPC: B01L3/00
Filed: 2009-09-23
Abstract: A droplet based assay comprising an emulsion including droplets packed in a three-dimensional arrangement, the droplets are reacted, such as thermocycled in this packaged form and then passed serially through a detector region to analyse individual droplets. Other inventions relate to formation of a plurality of emsulsions together and collecting data from individual droplets, these assays may be specific methods of nucleic acid amplification which include thermocycling and that may be conducted from a multiwall plate array of samples, a droplet transporter may pick-up droplets from a sample holder .
Patent GB-2520285-A (GB)
Title: Variable speed electro-mechanical drive
Inventor: CAINE JON EDWARD
IPC: H02K49/10
Filed: 2013-11-14
Abstract: A electrical machine 1 for driving one or more ancillary devices of a motor comprises first and second rotors 3,5, rotor 5 rotatably mounted relative to the rotor 3, and wherein the rotational speed of the rotor 5 of the electrical machine 1 depends upon a supply current to the electrical machine 1 and the rotational speed of the rotor 3. Rotor 3 (which may be considered as a rotating stator) is driven from a prime mover via belt 8 and rotor 5 drives the load. The current supply may be AC or DC. As shown rotor 3 carries permanent magnets 11 and rotor 5 winding 9 which windings may be three phase, the frequency of which adjusts the speed of the rotor 5 relative to rotor 3. The magnets and winding may be reversed and the arrangement operate synchronously or asynchronously. In an automobile application e.g. hybrid or electric, the load may be a water pump, air conditioning compressor or a supercharger. The machine may operate as a generator if rotor 5 rotates slower than rotor 3 and may operate as a motor if the belt drive is turned off.
Patent GB-2521382-A (GB)
Title: Session continuity apparatus
Inventor: HOLTMANNS SILKE
IPC: H04L29/08
Filed: 2013-12-18
Abstract: An embedded unit (3) in a vehicle initiates a session with a wireless device (10) also in the vehicle, and also with an external server or service provider (7), e.g. for navigation instructions. A token having a certain expiry period is periodically generated by the embedded unit and sent to the wireless device, which returns an acknowledgment. If a user wishes to exit the vehicle, the wireless device is carried with the user and, when out of range of the unit, no acknowledgment to the last token will be received. At this point the session with the server is paused, and may either be resumed once the wireless device is returned to the vehicle or transferred to the wireless device when outside the vehicle using a token generated by the server. The session with the server may be initiated by the wireless device, after which the embedded unit may also be allowed to participate.
Patent GB-2513050-A (GB)
Title: Detection and treatment of breast cancer
Inventor: ELLENBERG JAN
IPC: A61K38/17
Filed: 2012-12-20
Abstract: The present invention describes methods for determining the risk that a breast precursor lesion will progress to invasive breast cancer and/or the risk of recurrent non-invasive disease in a patient, comprising detecting the presence and/or level of PAPPA and/or PAPPA functional activity in a breast tissue sample obtained from the patient, wherein if PAPPA is not present, or is present at a reduced amount compared to a control, there is the risk of progression to invasive cancer and/or the risk or recurrent disease. In an alternative embodiment, the diagnosis can be carried out by identifying the proportion of mitotic cells in a patient sample that are in prophase or pro- metaphase, wherein if the proportion of cells in prophase or pro-metaphase is 30% or more,this indicates a risk of progression to invasive breast cancer and/or risk of recurrent disease. The present invention also enables the chemosensitisation of mitotically delayed breast cancer cells to anti-proliferative agents, preferably anti-mitotic agents, by restoring normal progression through mitosis. In this embodiment a first drug is applied to release breast cancer cells from the mitotic block and, sequentially,a second drug affecting proliferating cells is administered for cancer cell killing.
Patent GB-2529463-A (GB)
Title: Apparatus and method for steering marine sources
Inventor: MARSHALL DEAN WILLIAM
IPC: G01V1/38
Filed: 2014-08-21
Abstract: A seismic survey system for in-sea use comprises at least one winch 2 mounted onto a tow vessel, a winch line coupled to a floated drag device 8 and a calibrated line counter on the winch for accurate pay in and out readings, the floated drag device being coupled to a separation rope of a seismic source array. The position of the seismic source array relative to the tow vessel centre line may be controlled. The system may further comprise winches mounted on the vessel comprising winch lines coupled to floated drag devices attached to streamer (10, figure 4) separation ropes (11). The system may be used for conducting 4D seismic surveys.
Patent GB-2529481-A (GB)
Title: Subsea dynamic load absorber
Inventor: MCINTOSH MURRAY JAMIESON
IPC: F16F15/06
Filed: 2014-08-22
Abstract: A load absorber 30, mounted in use on a subsea body 20, is cooperable with an actuating member 32 such as a male piston element or a female cup on an opposed subsea body 18. The load absorber comprises a hollow structure defining an internal flow path 48, 50, 52, 54 for water. A flow restrictor acting on the flow path restricts a distal flow of water along the flow path from a proximal opening 46, caused by convergence between the actuating member and the load absorber. The flow restrictor comprises a shuttle element 68 to restrict the flow path that is mounted to the structure for automatic movement from a first state to a second state (Fig 5) in response to an increase in water pressure at the proximal opening. In the first state, the shuttle element may effect greater restriction of the flow path than in the second state. A method of using the load absorber is also disclosed.