baber/WOPTO huggingface dataset:
Patent IL-103064-A0 (IL)
Title: Diastereomers of 1-(isopropoxycarbonyloxy)ethyl 3-cephem-4-carboxylate and processes for their preparation
IPC: A61K31/545
Filed: 1992-09-04
Abstract: Enterally absorbable diastereomers of (6R,7R)-7-[2-(2-aminothiazol-4-yl)-2-(Z)-(methoxyimino)acetamido]-3-(m ethoxymethyl)-3-cephem-4-carboxylic acid 1-(isopropoxycarbonyloxy)ethyl ester of the formula I <IMAGE> and its physiologically acceptable salts and also diastereomerically pure salts of the compounds of the general formula II <IMAGE> where HX represents a mono- or polybasic acid and where X represents an inorganic or organic physiologically acceptable anion, and a process for the preparation of these compounds of the formula I or II are described, which is characterised in that on mixing together one equivalent of a solution of the diastereomer mixture of the formula III with 0.2 - 2 equivalents of a solution of the acid component HY the more poorly soluble diastereomer of the general formula IV is first precipitated and separated off by filtration, then the more readily soluble diastereomer of the general formula IV is precipitated from the filtration solution, it being possible in the subsequent subsidiary steps for the acid components HY to be identical or different and any desired sequence of the addition of different acid components HY to be used, and the salts obtained are optionally further purified by crystallisation.
Patent IL-105858-A0 (IL)
Title: Dimeric piperidine,tetrahydropyridine and piperazine derivatives
IPC: C07D211/44
Filed: 1993-05-31
Abstract: This subject invention relates to dimeric 4-phenylpiperidine, 4-phenyl-1,2,3,6-tetrahydropyridine, or 4-phenylpiperazine compounds or dimeric spirocyclic piperidine compounds having general formula (I), wherein n is 1-5; R1 to R4 are substituents; R5 and R6 each hydrogen or alkyl or form together an ethylene or propylene bridge; X is O, S, SO, SO2, CO or (CH2)m, m being 0 or 1, X is NR7, R7 being H, alkyl, cycloalkyl, cycloalkylalkyl, phenyl, or phenylalkyl, or X is CR8-R9, wherein R8 and R9 are selected from hydroxy and the substituents defined under R7; and (i) Z1 is a substituent and Z2 is (CH2)p wherein p is 0; and Y is N, C or CH; (ii) Z1 and Y are linked together via a single bond, thereby forming a spirocyclic junction; in which case Y is C; Z1 is O, S, (CH2)q, q being 1, 2 or 3, or Z1 is CH2O, CH2S, CH2CH2O, CH2CH2S, CH=CH, CH=CHCH2, CH2OCH2, CH2SCH2, CH=CH-O, or CH=CH-S; and Z2 is O, S or (CH2)p, p being 0 or 1; are potent sigma receptor ligands thus being useful as drugs for the treatment of anxiety, psychosis, epilepsy, convulsion, movement disorders, motor disturbances, amnesia, cerebrovascular diseases, senile demential of the Alzheimer type or Parkinson's disease.
Patent IL-119719-A0 (IL)
Title: Inorganic fullerene-like structures of metal chalcogenides
IPC: G02F1/1524
Filed: 1996-11-29
Abstract: A method for the preparation of nanoparticles of metal oxides containing inserted metal particles and to metal-intercalated and/or metal-encaged "inorganic fullerene-like" (hereinafter IF) structures of metal chalcogenides obtained therefrom is provided, which comprises heating a metal I material with water vapor or electron beam evaporation of said metal I material with water or another suitable solvent, in the presence of a metal II salt, and recovering the metal II-doped metal I oxide, or proceeding to subsequent sulfidization, yielding bulk quantities of metal II-intercalated or metal II-encaged IF structures of the metal I chalcogenide. The metal II salt is preferably an alkaline, alkaline earth or transition metal salt, most preferably an alkali chloride. The intercalated and/or encaged IF structures are usable as lubricants. They also form stable suspensions, e.g. in alcohol, and electrophoretic deposition from said suspensions yields thin films of the intercalated IF materials, which have a range of potential applications.
Patent IL-130001-A0 (IL)
Title: Diphenylalkyl-tetrahydropyridines process for their preparation and pharmaceuticals compositions containing them
IPC: C07D211/70
Filed: 1997-12-12
Abstract: PCT No. PCT/FR97/02289 Sec. 371 Date Jul. 27, 1999 Sec. 102(e) Date Jul. 27, 1999 PCT Filed Dec. 11, 1997 PCT Pub. No. WO98/25904 PCT Pub. Date Jun. 18, 1998The invention relates to compounds of the formula in which: Y is -CH- or -N-; R1 is a halogen or a CF3, (C1-C4)alkyl or (C1-C4)alkoxy group; R2 and R3 are each hydrogen or a (C1-C3)alkyl; n is 0 or 1; and Ph1 and Ph2 are each independently an unsubstituted, monosubstituted or polysubstituted phenyl group; to a process for their preparation and to the pharmaceutical compositions containing them. These compounds have neurotrophic and neuroprotective activity.
Patent IL-131546-A0 (IL)
Title: Device for urine testing
IPC: C12Q/
Filed: 1997-03-05
Abstract: The present invention concerns a device for testing resistance in microorganisms present in e.g. urine. The device comprises a cylindric container (1) fitted with a spout (3) of a considerably lesser diameter and a plunger (2) making a tight seal against the wall of the container (1), having a radially extending gasket (6) and being partly coated with nutrients for growing microorganisms, the coated part being arranged at the front part of the plunger (2) and comprising at least three angularly arranged test laminate (4A, 4B, 4C), at least one of which is coated with nutrients and antibiotics of different kinds and concentrations. The lower end surface (Ä) of the container (1) is conically shaped with a peak turning into the spout (3) preventing urine from remaining on the surface (Ä) when the container (1) is emptied after the laminae (4A, 4B, 4C) have been wetted with urine and before the device is incubated.
Patent IL-133511-A0 (IL)
Title: Method for the preparation of citalopram
IPC: C07C229/38
Filed: 1998-03-03
Abstract: A method for the preparation of citalopram comprising the steps of reacting a compound of Formula (IV) wherein R1 is C1-6 alkyl and X is O or NH, successively with a Grignard reagent of 4-halogen-fluorophenyl and a Grignard reagent of 3-halogen-N,N-dimethylpropylamine, respectively, effecting ring-closure of the resulting compound of Formula (V) wherein R1 and X are as defined above, and converting the resulting 1,3-dihydroisobenzofuran compound to the corresponding 5-cyano derivative, i.e. citalopram.
Patent IL-137120-A0 (IL)
Title: Process for preparing (r)-2-bromo-3-phenyl-propionic acid
IPC: C07C51/363
Filed: 1999-01-26
Abstract: It is described a process for preparing (R)-2-bromo-3-phenyl-propionic acid starting from (D)-phenyl-alanine, sodium nitrite and concentrated hydrobromic acid in a mixture of an aqueous solvent and a solvent selected from the group consisting of halogenated hydrocarbons and aromatic hydrocarbons.
Patent IL-140337-A0 (IL)
Title: Process for preparing a polyvinyl alcohol gel
IPC: C08J3/075
Filed: 1999-03-30
Abstract: A polyvinyl alcohol gel can be easily and quickly produced by a process having the following steps: (a) use of an aqueous polyvinyl alcohol solution with a degree of hydrolysis >/=98 % by moles; (b) admixture of an additive that is dissolved in the aqueous polyvinyl alcohol solution and forms a separate, finely distributed and aqueous phase after concentration of the solution; (c) drying of the aqueous solution to a residual water content of maximum 50 wt. % to cause the phases to separate and hence the polyvinyl alcohol to gel; (d) rehydrating the polyvinyl alcohol in an aqueous medium.
Patent IL-142169-A0 (IL)
Title: Aerosol generator and method of making and using an aerosol generator
IPC: A24F40/70
Filed: 1999-10-14
Abstract: An aerosol generator includes a flow passage having an inlet and an outlet, a heater arranged relative to the flow passage for heating the flow passage, a source of material to be volatilized in communication with the inlet of the flow passage, a valve to open and close communication between the source of material and the inlet of the flow passage, and a pressurization arrangement for causing material in the source of material to be introduced into the flow passage when the valve is in an open position. The aerosol generator further includes a source of power for operating the heater and the valve, and a control device for controlling supply of power from the source of power to the heater and the valve. A metering device in an inhaler includes a pressurized source of medicated fluid and a metering chamber configured to deliver a predetermined volume of fluid to a heated flow passage in the inhaler. The metering chamber can be part of a rotary valve having a bore and a displacement member moveable within the bore from a first position where the fluid is loaded into the bore to a second position where the predetermined volume is ejected out of the bore. Another metering chamber has an elastic portion of a delivery passage in fluid communication with the pressurized source of liquid and the elastic portion of the delivery passage is deformed to eject the predetermined volume.
Patent IL-143741-A0 (IL)
Title: Vacuum cleaner
IPC: A47L9/10
Filed: 1999-12-06
Abstract: The invention provides a vacuum cleaner (10) having a chassis (12), supporting wheels (14) mounted on the chassis (12), drive means (15) connected to the supporting wheels (14) for driving the supporting wheels (14) and a control mechanism for controlling the drive means (15) so as to guide the vacuum cleaner (10) across a surface to be cleaned. A cleaner head (22) having a dirty air inlet (24) facing the surface to be cleaned is mounted on the chassis (12) and separating apparatus (52) is supported by the chassis (12) and communicates with the cleaner head (22) for separating dirt and dust from an airflow entering the vacuum cleaner (10) by way of the dirty air inlet (24). The separating apparatus (52) comprises at least one cyclone(54,56). This type of separating apparatus is not prone to clogging and therefore the pick-up capability of the cleaner (10) is maintained at a high standard.
Patent IL-149164-A0 (IL)
Title: Methods and compositions utilizing quinazolinones
IPC: A61P9/08
Filed: 2000-10-26
Abstract: Quinazolinones of formulae (1a), (1b), (1c) and (1d) are disclosed. They are useful for treating cellular proliferative diseases and disorders associated with KSP kinesin activity.
Patent IL-160649-A0 (IL)
Title: Methods for inhibiting cognitive deterioration in adults with down syndrome
IPC: A61P25/28
Filed: 2002-08-27
Abstract: This invention generally pertains to the field of psychiatry. In particular, this invention pertains to the discovery that agents capable of inhibiting the binding of cortisol to its receptors can be used in methods for preventing or reversing cognitive deterioration in adults with Down's syndrome. Mifepristone, a potent specific glucocorticoid receptor antagonist, can be used in these methods. The invention also provides a kit for preventing or reversing cognitive deterioration in a DS patient including a glucocorticoid receptor antagonist and instructional material teaching the indications, dosage and schedule of administration of the glucocorticoid receptor antagonist.
Patent IL-175714-A0 (IL)
Title: Quinazolinone compounds as anticancer agents
IPC: C07D401/06
Filed: 2006-05-17
Abstract: Quinazolinone compounds, pharmaceutically acceptable salts, and prodrugs thereof; compositions that include a pharmaceutically acceptable carrier and one or more of the quinazolinone compounds, either alone or in combination with at least one additional therapeutic agent. Methods of using the quinazolinone compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of proliferative diseases.
Patent IL-190620-A0 (IL)
Title: Method for producing antimicrobial plastic compositions
Filed: 2008-04-03
Abstract: The present invention relates to a process for preparing antimicrobial plastics compositions comprising a thermoplastic, particularly of thermoplastic elastomer, and at least one pulverulent antimicrobial active ingredient, specifically from the group of the bis(4-amino-1-pyridinium)alkanes, and to the use of this plastics composition for catheters and other medical-technology products.
Patent IL-194898-A0 (IL)
Title: Improved ground covering
Filed: 2008-10-23
Abstract: A temporary ground covering for displacement on sandy, muddy or boggy ground. The covering includes a woven structure formed of warp and weft. The weave is such that each warp thread interlaces with the weft thread, following approximately half the intersections of the rows and columns of the weave. The warp thread is left in the remaining intersections for each warp thread to obtain at least one simple tight weave area followed by an area of floats. The alternation of the different areas causes contractions of the weft thread creating a significant relief of the obtained fabric. The covering includes flat threads over at least one part of the width of the woven structure on at least one of the surfaces. Each thread is taken, steadily or not, by weft threads placed at the end of the projections of the woven surface structure.
Patent RO-125489-A0 (RO)
Title: Swivelling electrical motor with short-circuited mobile coil
Inventor: GEORGESCU DANIEL ŞTEFAN
IPC: H02K33/14
Filed: 2009-04-21
Abstract: The invention relates to a swivelling electrical motor with short-circuited mobile coil, supplied with alternating current and meant to drive hard magnetic disks. According to the invention, the motor comprises a rolled magnetic core (1) whereon, on a half of the circumference thereof, there are placed two fixed coils (2 and 2') successively supplied from the same alternating current source and which acts on a short-circuited mobile coil (3) arranged concentrically with the fixed coils (2 and 2'), the mobile coil (3) performing an angular motion between two fixed components consisting of some position transducers (4 and 4') playing the role of controlling the switching of the supply between the two fixed coils (2 and 2') the mobile coil (3) being fastened at the extremity of an arm (5) mechanically coupled with a shaft (6) which may rotate in two bearings (7 and 7').
Patent RO-128802-A0 (RO)
Title: Phyto-therapeutical combinations for the prevention and treatment of cutaneous aging, with effect of repairing affected dermo-epidermal structures
Inventor: ZGLIMBEA LENUTA
IPC: A61K36/537
Filed: 2012-09-28
Abstract: The invention relates to a phyto-therapeutic product used in dermatology. According to the invention, the product consists, in mass percentages, of 0.01...0.5% extract of Salvia officinalis, 1...5% extract of Medicago sativa, 0.5...1.5% extract of Viola tricolor and usual ingredients for conditioning.
Patent RO-129307-A0 (RO)
Title: Compact composite monolithic laser system with simultaneous delivery of two laser beams
Inventor: DASCĂLU TRAIAN
IPC: F02P23/04
Filed: 2013-05-30
Abstract: The invention relates to a compact composite monolithic laser system with simultaneous delivery of two laser beams, meant to operate as system for igniting the laser-fuel mixture in a combustion chamber of an engine. According to the invention, the laser system comprises a laser crystal () having the central area formed by Nd : YAG, attached to two prisms () and a crystal () doped with Cr: YAG which acts as passive switch, the lower part of the thus formed assembly being covered with multiple dielectric layers, the entire assembly being attached to a mechanical support () by using a resin with high content of metal powder, the optical pumping being performed by two laser diodes coupled to two optical fibers, having the output end cut at an adequate angle in order to provide minimum losses upon entering a prism; the optical resonator consists of some partially reflecting mirrors, applied directly on the active medium Nd : YAG and of another highly reflective mirror applied directly on the passive switch Cr: YAG, the pumping radiation emitted by a pumping source being delivered by the optical fibers onto the surfaces of the prisms wherefrom it is propagated, by total internal reflection, into the active medium where it is uniformly absorbed by the active ions and produces a population inversion, and when the population inversion reaches the threshold level, the passive switch is saturated fast to result in a giant laser pulse, and the fact that the laser resonator has two extraction mirrors, allows two laser pulses to result and be focused by two lenses and pass through some protection windows towards a combustion chamber of an engine.
Patent RO-133455-A0 (RO)
Title: Writing assistant for non-digital media using customized and contextual information
Inventor: POPA MARIA GEORGIANA
IPC: G10L15/26
Filed: 2018-08-07
Abstract: The invention relates to a method of user's writing assistance, meant for non-digital media, by means of which the reduction or the elimination of the differences between hand written and digital written data is intended. According to the invention, the method consists in: using customized information, namely one or more writing samples, possibly audio samples, mapping the physical writing area and creating a digital equivalent thereof, with the possibility of displaying some helping texts on the writing area, recording and keeping evidence of the modifications made by the user, so as to obtain, in the end, a digital version of the information written by hand, without requiring the transcription thereof.
Patent RO-135352-A0 (RO)
Title: Dynamically articulated chair with divided seat
Inventor: MORARU GILBERT MANUEL
IPC: A47C31/12
Filed: 2021-07-30
Abstract: The invention relates to a chair with a divided seat, meant to support a user's body in order to offer him/her an anatomically correct and also a comforting position, throughout the entire period of use. According to the invention, the chair has a seat (1) consisting of two half-seats (1L and 1R), each covered with a sponge (13L and 13R), symmetrical to the median plane, each of the two half-seats (1L and 1R) consisting of two seats (11L, 11R and 12L, 12R), a rear and a front one, respectively,  connected by a joint provided with a pin (14), each of the two half-seats (1L and 1R) being provided with a mechanism (2L and 2R) for adjusting the upward and lateral pressures, mounted under the half-seats  (1L and 1R) laterally positioned on either side towards the outside, symmetrically to the median plane, and a mechanism (3L and 3R) for adjusting angles and distances and adjusting the inclinations of the half-seats (1L and 1R).
Patent MC-1791-A1 (MC)
Inventor: THOMAS-PAUL ZIMMERMAN
IPC: A61K31/70
Filed: 1987-01-29
Abstract: This invention relates to synergistic combinations of nucleoside analogues, which are converted to viral DNA polymerase inhibitors through the action of at least one virus-induced enzyme, and nucleoside transport inhibitors. These combinations are especially useful in combatting herpes virus infections.
Patent ZW-4994-A1 (ZW)
Title: Process of preparing cesium salts from cesium-aluminum-alum
Inventor: HOFMANN HARTMUT
IPC: C07C51/41
Filed: 1994-04-19
Abstract: PCT No. PCT/EP94/01202 Sec. 371 Date Nov. 24, 1995 Sec. 102(e) Date Nov. 24, 1995 PCT Filed Apr. 19, 1994 PCT Pub. No. WO94/25422 PCT Pub. Date Nov. 10, 1994This invention relates to the preparation of cesium salts from cesium-aluminum-alum in a process in which the cesium-aluminum-alum is reacted in a single vessel in the presence of water with calcium hydroxide in an amount which is equimolar to the amount of aluminum and with a readily water-soluble calcium salt in an amount which is equimolar to the amount of cesium and the precipitated aluminum hydroxide and the precipitated calcium sulfate are separated by filtration or centrifugation.
Patent MA-25127-A1 (MA)
Title: Etude et realisation d'un systeme didactique pour la commande de processus industriels.
Inventor: ISSAM ATOUF
IPC: G01N33/36
Filed: 2000-06-05
Abstract: NOTRE INVENTION ENTRE DANS LE CADRE D'UN SYSTèME DIDACTIQUE POUR L'APPRENTISSAGE DE LA PROGRAMMATION DITE BAS NIVEAU,  ET DE LA COMMANDE DE PROCESSUS INDUSTRIELS.  LE SYSTèME QUE NOUS AVONS DÉVELOPPÉ EST UN SYSTèME MICROKIT à BASE DU MICROPROCESSEUR Z-8O,  CE MICROKIT EST ÉQUIVALENT à UN SYSTèME MICRO-ORDINATEUR PRÉSENTANT DES CARECTÉRISTIQUES MATÉRIELLES ET LOGICIELLES TRèS ÉLABORÉES.  IL N'EST PAS DESTINÉ UNIQUEMENT à DES APPLICATIONS INDUSTRIELLES SPÉCIFIQUES, MAIS IL PEUT eTRE UTILISÉ COMME UN SYSTèME DIDACTIQUE POUR L'APPRENTISSAGE DE LA PROGRAMMATION DITE BAS NIVEAU OU LANGAGE MACHINE ET CECI,  EN LEUR PERMETTANT DE DÉVELOPPER DES PROGRAMMES ÉCRITS EN ASSEMBLEUR ET DE LES ÉXECUTER SUR LE SYSTèME.  LE FONCTIONNEMuENT DU SYSTèME EST CONTROLÉ PAR UN MONITEUR RÉSIDENT DANS UNE MÉMOIRE MORTE EPROM.  IL PERMET AUX UTILISATEURS DE DISPOSER D'UN ENSEMBLE COMPLET DE COMMANDES AU CLAVIER QUI LEURS FACILITENT L'UTILISATION DE L'UNITÉ CENTRALE,  DE LA MÉMOIRE ET DE TOUTES LES UNITÉS D'ENTRÉE/SORTIES.
Patent MA-37743-A1 (MA)
Title: Procédé de préparation de triazolopyridines substituées
Inventor: SCHULZE VOLKER
IPC: C07D471/04
Filed: 2015-01-07
Abstract: La présente invention concerne des procédés de préparation de composés de triazolopyridine substituée de formule générale (i) tels que décrits et définis dans la description, ainsi que des composés intermédiaires utiles dans la préparation desdits composés.
Patent MA-38675-A1 (MA)
Title: Dérivés de nucléosides 4'-fluoro-2'-méthyle substitués utiles pour inhiber la replication de l'hepatite c (hcv)
Inventor: SMITH MARK
IPC: C07H19/04
Filed: 2014-05-15
Abstract: La présente invention concerne des dérivés de nucléosides 4'-fluoro-2'-méthyle substitués, des compositions pharmaceutiques comprenant lesdits dérivés et des méthodes d'utilisation de ces composés et/ou des compositions de ceux-ci, pour le traitement du vhc.
Patent MA-52679-A1 (MA)
Title: Optimisation du compostage des dechets de fumier de cheval et des grignons d'olives associes aux dechets verts et leur valorisation agronomique
Inventor: MEDDICH Abdelilah
IPC: C05F17/00
Filed: 2021-03-03
Abstract: Au maroc, la production de déchets organiques ne cesse d'augmenter ces dernières années. Cependant, plus de 80 millions de tonnes de déchets organiques sont produites en permanence chaque année sans aucun traitement. De même, des quantités énormes de déchets organiques d’origine animale et agro-industrielle tels que le fumier de cheval et les grignons d’olives sont générées. L'épandage de ces déchets non traités préalablement dans les décharges a conduit à la pollution des écosystèmes (sol, eau et air). De plus, il est intéressant de chercher des solutions environnementales pour réduire l’impact négatif de ces déchets pour conserver et sauvegarder la durabilité et la productivité de ces écosystèmes. En effet, l’optimisation du recyclage de ces déchets en fertilisants organiques sains et stables est devenu un moyen efficace et un acte environnemental nécessaire pour la protection, la conservation et la restauration de la productivité des sols agricoles. Par ailleurs, la biotransformation des déchets à base de fumier de cheval et de grignons d’olives par le processus de compostage nécessite leur association à d'autres composés organiques tels que les déchets verts. Dans ce travail, une nouvelle solution écologique à faible coût est proposée en associant le fumier de cheval et les grignons d’olives aux chiendents et à des proportions adéquates. Les paramètres physico-chimiques et agronomiques, les biotests de phytotoxicité et l'analyse par spectroscopie infrarouge évalués ont montré qu’après trois mois de co-compostage les deux composts a1 (fumier de cheval-déchets verts) et a2 (grignons d’olives-déchets verts) en comparaison avec le compost a3 (à base de déchets verts seuls) sont susceptibles d’être utilisés dans les pratiques d'agriculture biologique comme amendements organiques. De même, l'état de maturité des composts finaux a1 et a2 est conforme à la norme nfu 44-051 et ils peuvent être exploités dans le secteur de l’agriculture biologique durable pour améliorer la qualité et la productivité des cultures sans aucun danger.