baber/WOPTO huggingface dataset:
Patent NZ-278595-A (NZ)
Title: Asymmetric cyclopenta-beta-amino acids and derivatives
Inventor: MITTENDORF JOACHIM
IPC: C07C69/74
Filed: 1995-01-09
Abstract: Prepn. of enantiomerically pure cyclopentane- or cyclopentene- beta -aminoacids of formula (I) comprises:(a) converting a meso-cyclopentane- or cyclopentene dicarboxylic anhydride of formula (II) into an enantiomerically pure monoester of formula (IVa) via enantiomerically pure salt of formula (IV), by asymmetric alcoholysis with an alcohol of formula (III) in a solvent in presence of an equimolar amt. of a chiral amine base in pure enantiomer form;(b) activating the free carboxy function then reacting with liq. ammonia to give the enantiomerically pure amide of formula (V);(c) cleaving the ester residue R<15> in an inert solvent in presence of a nucleophilic auxiliary, by enzymatic methods or in presence of a palladium catalyst to give the acid or salt of formula (VI);(d) carrying out Hoffmann rearrangement with alkali(ne earth) metal hypochlorite in aq. alkali(ne earth) metal hydroxide soln.;(e) blocking the free amino gp. in soln. using a conventional amino-protecting gp., isolating the protected cpds. and cleaving the protecting gp. to give the pure enantiomer of (I). A,L = H;D, E = H, halo, OH or 1-8C alkyl,etc.; or D+E = =CR<6>R<7>, =N-OH, =O or =S; or A+D or E+L = additional bond;R<6>, R<7> = H, halo, 1-8C alkyl, 1-8C alkoxy,etc.; R<2> = H, amino-protecting gp., 1-8C alkyl (opt. substd. by 1 or 2 of OH, CHO up to 6C acyl, phenyl and benzoyl, where phenyl and benzoyl are themselves opt. substd. by 1 or 2 of halo, NO2, CN and 1-6C alkyl),etc.;R<3> =H or 1-8C alkyl (opt. substd. by phenyl); or R<2>+R<3> = =CHR<14>;R<14> = H or 1-8C alkyl (opt. substd. by halo, OH,etc.;T = O, S or NH; R<1> = H, 1-8C alkyl (opt. substd. by 1-3 of OH, halo,etc.), phenyl (opt. substd. by 1-3 of OH, halo, NO2,etc.);or if T = e.g. NH, R<15> = 2-5C alkyl or 2-5C alkenyl (opt. substd. by CN, SiMe3, Ph or CCl3);V = chiral amine base;X = H, alkali metal or alkaline earth metal. Enantiomerically pure cpds. (IV), (IVa) and (V) are new.
Patent NZ-281183-A (NZ)
Title: Imidazo[1,2-a]quinoxaline derivatives and medicaments
Inventor: JEPPESEN LONE
IPC: A61K31/495
Filed: 1995-01-30
Abstract: Imidazo[1,2-a]quinoxalinone derivatives of the general formula   <IMAGE>   wherein R1, R2, R3 are the same or independently are H, alkyl, alkoxy, halogen, NO2, NH2, CF3, CN, SO2CH3, SO2CF3, SO2NR'R'' or a 5- or 6-membered N-containing heterocyclic ring, optionally substituted, and R', R'' are independently H or alkyl; and R4 is H or CH2-R6; and R6 is H, halogen, POR'''R'''', NR7R8 or a 5- or 6-membered N-containing heterocyclic ring optionally substituted, and R''', R'''' are independently hydroxy or alkoxy; and   <IMAGE>   R7, R8 are the same or independently are H, or alkyl optionally substituted; and n is 1, 2 or 3; R5 is   <IMAGE>    <IMAGE>   and R9 is OH, alkoxy, H or NR10R11; and R10, R11 are the same or independently are H, NH2 or OH; and X is O or S; and Y is O, S or NH2, and pharmaceutically acceptable salts thereof, have affinity for the AMPA receptors and are antagonists in connection with this type of receptor which makes them useful in the treatment of CNS ailments, especially in the treatment of any of the numerous indications caused by hyperactivity of excitatory amino acids.
Patent NZ-331243-A (NZ)
Title: Intraluminal stent having a locking mechanism comprising teeth and a slot
Inventor: WILLIAMS MICHAEL S
IPC: A61F2/06
Filed: 1995-11-14
Abstract: An intraluminal stent includes a locking mechanism comprising a substantially flat sheet having a first edge 40 and a second edge 42, a longitudinal slot 48 adjacent edge 42 and a plurality of teeth 50 positioned along a third edge 44 and a fourth edge of the stent for interlocking engagement with the slot.  The teeth are made from a shape memory-retaining material or a superelastic material so that when the stent is rolled into a cylindrical configuration and expanded to an enlarged diameter the teeth interlock with the slot.
Patent NZ-334948-A (NZ)
Title: Anthranilic acid derivatives as p-glycoprotein inhibitors useful for the treatment of multi drug-resistant cancers
Inventor: RYDER HAMISH
IPC: C07D217/24
Filed: 1997-10-17
Abstract: An anthranilic acid derivative of formula (I), wherein: each of R, R1 and R2, which are the same or different, is H, C1-C6 alkyl, OH, C1-C6 alkoxy, halogen, nitro, or, N(R1OR11) wherein each of R1O and R11, which are the same or different, is H or C1-C6 alkyl, or R1 and R2, being attached to adjacent positions of ring b, together form a methylenedioxy or ethylenedioxy group; R3 is H or C1-C6 alkyl; R4 is C1-C6 alkyl or R4 represents -CH2- or -CH2CH2- which is attached either (i)	to position 2 of ring b to complete a saturated 5- or 6-membered nitrogen-containing ring fused to ring b or (ii)	to the position in ring a adjacent to that to which X, being a single bond, is linked, thereby completing a saturated 5- or 6-membered nitrogen-containing ring fused to ring a; R5 is H, OH or C1-C6 alkyl; X is a direct bond, 0, S, -S-(CH2)p- or -0-(CH2)p- wherein p is an integer of 1 to 6; R6 is H, C1-C6 alkyl or C1-C6 alkoxy; q is 0 or 1; Ar is an unsaturated carbocyclic or heterocyclic group selected from furan, thiophene, pyrrole, indole, isoindole, pyrazole, imidazole, isoxazole, oxazole, isothiazole, thiazole, pyridine, quinoline, quinoxaline, isoquinoline, thienopyrazine, pyran, pyrimidine, pyridazine, pyrazine, purine and triazine which is unsubstituted or substituted by one or more substituents selected from OH, halogen, C1-C6 alkyl, which is unsubstituted or substituted by halogen, C1-C6 alkoxy, nitro and N(R1OR11); each of R7 and R8, which are the same or different, is H, C1-C6 alkyl which is unsubstituted or substituted by one or more halogen atoms, C1-C6 alkoxy, hydroxy, halogen, phenyl, NHOH, nitro, N(R1OR11), or SR12 wherein R12 is H or C1-C6 alkyl; or R7 and R8, when situated on adjacent carbon atoms, form together with the carbon atoms to which they are attached a benzene ring or a methylenedioxy substituent; R9 is phenyl or an unsaturated heterocyclic group selected from furan, thiophene, pyrrole, indole, isoindole, pyrazole, imidazole, isoxazole, oxazole, isothiazole, thiazole, pyridine, quinoline, quinoxaline, isoquinoline, thienopyrazine, pyran, pyrimidine, pyridazine, pyrazine, purine and triazine, each of which is unsubstituted or substituted by C1-C6 alkyl, OH, C1-C alkoxy, halogen, C3-C6 cycloalkyl, phenyl, benzyl, trifluoromethyl, nitro, acetyl, benzoyl or N(R1OR11), or two substituents on adjacent ring positions of the phenyl or heterocyclic group together complete a saturated or unsaturated 6-membered ring or form a methylenedioxy group; n is 0 or 1; and m is 0 or an integer of 1 to 6; Also disclosed are pharmaceutical compositions containing the above compound that can be used as an inhibitor of p-glycoprotein.  The compound is useful as a modulator for multidrug resistance, for potentiating the cytotoxicity of a chemotherapeutic agent or enhancing the net absorption, distribution, metabolism or elimination characteristics of a therapeutic agent
Patent NZ-335325-A (NZ)
Title: Erythromycin derivatives, method for preparing them and their use as medicine
Inventor: AUGER JEAN-MICHEL
IPC: A61P31/04
Filed: 1997-12-10
Abstract: The specification describes above erythromycins of formula (I) in which R represents an alkyl radical containing up to 18 Carbons,optionally substituted or (CH2)nAr, n representing a whole number ranging from 1 to 4 and Ar representing an aryl or heteroaryl radical optionally substituted, and Z represents a hydrogen atom or an acyl radical of up to 12 Carbons. The compounds of formula (I) have very interesting antibiotic properties.
Patent NZ-503010-A (NZ)
Title: Rawlplug fixing with non uniform taper and tool for preparing a hole for the fixing
Inventor: WALLACE THOMAS CAMPBELL
IPC: B26F1/32
Filed: 1998-07-31
Abstract: The fixing has an elongated body with two opposite ends and a bore (4) extending into it from one end to receive a fixing member, like a screw. The other end of the body is tapered inwardly to a leading end of the body (2) to an extent allowing the fixture to be driven into a wall of building material. The other end is further provided with a non-uniform taper of: (a)  between 12o to 18 o to the longitudinal axis of the body (2) at the leading end; and (b)  from 4 o to 8 o to the longitudinal axis of the body (2) at a portion remote from the leading end.
Patent NZ-508056-A (NZ)
Title: Use of a natural substance containing thymol in the manufacture of animal feed
Inventor: AEBI ROBERT
IPC: A23K20/195
Filed: 1999-05-06
Abstract: The use of a natural substance occurring in nature and obtained from natural products or through synthesis, wherein the natural substance contains thymol, in the manufacture of an animal feed, an animal feed additive or a premix to be added to the additive or a drinking water supplement for the alleviation, cure or prevention of diseases caused by clostridium sp. in the intestinal tracts of animals.
Patent NZ-521005-A (NZ)
Title: Transgenic animal model for obesity expressing FOXC2 useful for identifying antiobesity drugs
Inventor: ENERBACK SVEN
IPC: C12Q1/02
Filed: 2001-02-16
Abstract: A method for identifying or screening for a compound useful for the treatment of a medical condition related to obesity, said method comprising the steps (i) contacting a test compound with the human FOXC2 gene; and (ii) determining whether said test compound activates the expression of the human FOXC2 gene, such activation being indicative for a compound useful for the treatment of a medical condition related to obesity. Such methods may be carried out in a non-human mammalian animal, wherein the method comprises exposing a non-human mammalian animal to a test compound, and determining the activity or stimulation of the human FOXC2 gene in said non-human mammalian animal. Animals useful in such methods include transgenic and genetically obese mice.
Patent NZ-527456-A (NZ)
Title: Equipment and method for measuring storage reaction
Inventor: TAJIMA HIDEJI
IPC: G01N35/10
Filed: 2002-02-12
Abstract: An equipment and a method for measuring storage reaction in which a reaction can be processed, measured and identified efficiently and quickly. The equipment for measuring storage reaction comprises a translucent storage section having an inlet/outlet of fluid, being fixed to each fixing position where a plurality of substances to be detected, each having a specified chemical structure, are arranged at a specified interval, and being capable of storing a basic member while allowing each chemical structure to correspond to each fixing position, a section for sucking/delivering the fluid from/into the containing section through the inlet/outlet, and a measuring equipment for receiving the light from the storage basic material at the outside of the storing section under a state corresponding to the fixing position.
Patent NZ-529299-A (NZ)
Title: A hot water tank of a water heater with an inlet diffuser
Inventor: ADAM QUENTIN ARTHUR CARL
IPC: F24H9/12
Filed: 2002-06-04
Abstract: A vertical cylindrical storage tank for hot water comprising an inlet diffuser fitting connected to an inner end of a cold water inlet tube located at a region of discharge of cold water into a lower portion of the tank. The diffuser has plural spaced distribution openings, each smaller across its transverse axis than the diffuser inlet but in total area of openings, much larger than the diffuser inlet. The spaced openings are substantially uniform and aligned upon assembly to deliver a discrete layer of cold water within the lowest portion of the storage space. This enables incoming cold water to be dispersed from the distribution openings uniformly in plural streamline flows into the storage space below the diffuser to minimise currents that cause mixing of hot and cold water in the tank so that a greater proportion of the tank's capacity can delivered continuously at the outlet as usefully hot water.
Patent NZ-530775-A (NZ)
Title: Frozen product of unleached or little leached minced fish meat
Inventor: MIZUGUCHI TORU
IPC: A23L17/00
Filed: 2002-08-01
Abstract: The disclosure relates to a method to provide a frozen product of unleached or little leached meat of a fish which has been usually taken after leaching. Also disclosed is fish meat in which iron in vivo, iron-containing substances and/or reductants in vivo have been oxidized. Additionally disclosed is a frozen product of unleached or little leached fish meat prepared by using minced fish meat or minced and dehydrated fish meat as a starting material, adding one or more freeze-denaturation inhibitors thereto and preventing the decomposition of trimethylamine-N-oxide due to oxidation. The disclosure also relates to a frozen product of unleached or little leached fish meat which is prepared by bringing the above-described fish meat into contact with oxygen by stirring to thereby prevent the decomposition of trimethylarnine-N-oxide and adding a freeze denaturation inhibitor followed by freezing and a frozen product of unleached or little leached fish meat prepared by adding a salt and stirring in the stirring stage also the ground fish meat products prepared therefrom.
Patent NZ-531481-A (NZ)
Title: Ophthalmic depot formulations for periocular or subconjunctival administration
Inventor: AHLHEIM MARKUS
IPC: A61K9/50
Filed: 2002-09-13
Abstract: An ophthalmic depot formulation for periocular or subconjunctival administration comprising microparticles of essentially pure active agent embedded in a biocompatible pharmacologically acceptable polymer, wherein said polymer is a polyactide-co-glycolide ester of a polycol, and wherein said polycol contains at least 3 hydroxy groups and has a molecular weight of up to 20,000.
Patent NZ-531579-A (NZ)
Title: Vertically rotating wind turbine system
Inventor: ELDER DILLYN M
Filed: 2001-09-26
Abstract: A lightweight vertically rotating wind turbine is disclosed. The turbine includes a tapered wind-collecting base, a vertically rotating shaft 1 having top 10 and bottom plates 4 at either end, a number of flat rotor blades 2 attached between the plates and spaced around the shaft to form a cage, and vertically oriented wind directing stator blades 5 adjacent the outer edges of the rotor blades. The bottom end of the shaft is connected to an energy transfer element 11 that is connected to an energy utilising device 12. The turbine further includes an open cover 10A formed from concentric braces including two side bearings, and a top shield having a central pivot point and an outer terminus above the side bearings. The open cover allows wind from the direction above the turbine to be harnessed, while the top shield creates a calm area between the shield and the top of the rotor cage.
Patent NZ-537152-A (NZ)
Title: Flower arrangement accessories
Inventor: WRIGHT DALE KATHLEEN
IPC: A41G1/00
Filed: 2003-05-09
Abstract: An accessory for providing an aperture through a container, including two interconnecting parts, a socket part (57) and an insert part (58) insertable into said socket part (57), at least one of said parts having a wall portion circumscribing a central bore (59) and arranged such that an insert portion of the insert part is sized to engage with a receiving portion of the socket part such that the parts may be operatively connected to one another with their respective bores in substantial alignment, and remote from said insert and receiving portions, each said part having container engagement means for engaging with respective walls in each of a base and a lid of the container when an orifice is cut therein.
Patent NZ-537389-A (NZ)
Title: Ash handling and treatment in solid fuel burners
Inventor: WILLIAMS PAUL DOUGLAS
Filed: 2002-01-09
Abstract: An agitator bed for fine particulate materials (ash) on the floor of a solid fuel gasifier includes a base surface 13 for supporting the ash, an array of agitator elements 182 arranged adjacent to and dispersed over the base surface, and a mechanism 188 to reciprocate the agitator elements through the ash on the base surface. The agitator elements are shaped so that when they are reciprocated through the ash they agitate the ash to encourage post-combustion and post-reduction of the ash and facilitate a net conveyance of the material in a predetermined direction toward discharge conveyor 54.
Patent NZ-537493-A (NZ)
Title: Pegylated T1249 polypeptide
Inventor: BAILON PASCAL SEBASTIAN
IPC: A61K47/48
Filed: 2003-07-16
Abstract: Pegylated T1249 polypeptide compounds are provided. Also provided are pharmaceutical compositions containing pegylated T1249 polypeptide compounds, and processes of making. Further provided is the use of pharmaceutical composition comprising, in admixture with a pharmaceutically acceptable excipient, a pegylated T1249 compound, for the preparation of a medicament for the inhibition of HIV infection.
Patent NZ-540400-A (NZ)
Title: An adjustable tray for supporting tools and equipment, such as tins of paint, on a ladder
Inventor: PICTON ARTHUR EDWARD
Filed: 2005-06-02
Abstract: A tray 1, for a ladder, comprises a body, the body being configured to be capable of storing and/or supporting equipment such as tools and tins of paint. A connector 10a, 10b releasably attaches the tray 1 to the ladder. The body includes at least two body portions 3a, 3b which are connected to one another so as to allow the length and/or width of the tray 1 to be altered by relative movement of the body portions with respect to one another.
Patent NZ-541217-A (NZ)
Title: Thienopyrimidinediones and their use in the modulation of autoimmune disease
Inventor: GUILE SIMON DAVID
IPC: A61P37/02
Filed: 2004-01-15
Abstract: Disclosed is a compound of formula (1), wherein R3 is a group CO-G or SO2-G and the remaining substituents are as defined in the specification. The compounds are inhibitors of T-cell proliferation and are useful in the modulation of autoimmune disease.
Patent NZ-547226-A (NZ)
Title: Articulated false seabed
Inventor: FRAENKEL PETER LEONARD
IPC: F03B13/10
Filed: 2004-12-03
Abstract: A support system for a water flow turbine 1, 2 includes a raft 3 on which the turbine can be mounted and that can be sunk into the water or floated on the surface WL, and a pair of struts 5 pivotally connected to an anchor 6 set into the bed SB of the water body and connected 8 to opposite ends of the raft. The struts are long enough so that the raft can be displaced between a lowered position sufficient to immerse the turbine and a raised position in which the turbine is above the water surface WL.
Patent NZ-553581-A (NZ)
Title: Methods and compositions for inhibition of innate immune responses and autoimmunity using immunoregulatory polynucleotides with a TGC sequence
Inventor: BARRAT FRANCK
IPC: A61K31/7088
Filed: 2005-08-24
Abstract: The use of an oligonucleotide comprising less than 200 bases or base pairs and further comprising an immunosuppressive or immunoinhibitory sequence for the treating a TLR7/8-dependent immune disease. The immunosuppressive or immunoinhibitory sequence is the trinucleotide sequence TGC at the 5' end of the oligonucleotide. The oligonucleotide does not include the immunostimulatory dinucleotide sequence CG wherein the C is unmethylated. The oligonucleotide can also be used to treat TLR7/8-dependent immune response and TLR9-dependent immune response.
Patent NZ-553665-A (NZ)
Title: Multipurpose adiabatic potable water production apparatus and method
Inventor: MERRITT THOMAS
IPC: F25B41/04
Filed: 2005-05-28
Abstract: Apparatus 10 for extracting potable water from air comprises a closed loop air duct 11, a fan 12 within the duct 11 producing a continuous flow of air in a predetermined direction, water introduction means, a first cooling element 14 and a first heating element 16. The closed loop air flow passes in sequence the fan 12, the water introduction means, the first cooling element 14 and the first heating element 16 before returning to the fan 12. The introduced water forms water vapour, causing adiabatic cooling in and increasing the absolute humidity of the downstream air which then passes over the first cooling element 14. As the first cooling element 14 has a surface temperature at or below the dew point of the flowing air, water vapour condenses on its surface and forms collectible liquid water. The air flow then passes over a first heating element 16 which heats the air thereby decreasing its relative humidity before the air returns to the fan 12. The apparatus allows the distillation of water with reduced energy costs. .
Patent NZ-563462-A (NZ)
Title: Sub-band voice codec with multi-stage codebooks and redundant coding
Inventor: WANG TIAN
IPC: G10L19/10
Filed: 2006-04-05
Abstract: A system comprises an audio processing tool configured to process a bit stream for an audio signal comprising a plurality of coded audio units. Each coded unit of the plurality of coded units comprises a field indicating whether the coded unit comprises main encoded information representing a segment of the audio signal; and whether the coded unit comprises redundant coded information representing the segment of the audio signal and which can be used in decoding corresponding main encoded information for the segment. Also disclosed is a method for processing an audio signal comprising at a processor of an audio processing tool, processing a bit stream for the audio signal and outputting a result. The bit stream comprises main coded information for a current frame that references a segment of a previous frame to be used in decoding the current frame; and redundant coded information for decoding the current frame, the redundant coded information comprising signal history information associated with the referenced segment of the previous frame. The audio processing tool is a real-time speech encoder and the result is encoded speech.
Patent NZ-564804-A (NZ)
Title: Fluidized bed reactor
Inventor: ZIMMER SEBASTIAN
IPC: B01J8/00
Filed: 2006-06-02
Abstract: Fluidised bed reactor comprises a fluidising chamber 4 and annular gas outlets 11 distributed across the circumference of the chamber 4, where the gas is evenly radially discharged from the reactor.
Patent NZ-565697-A (NZ)
Title: Method of generating an improved quality foam for a beverage through the use of calcium ions
Inventor: SHER ALEXANDER A
IPC: A23C11/00
Filed: 2006-06-30
Abstract: Disclosed is a method for generating an improved quality foam for a beverage, the method comprising: a) providing at least one foaming source (such as dairy proteins, non-dairy proteins, demineralised whey protein isolate products, low mineralised whey protein isolate products and any combination thereof) ; b) providing a multivalent ion source; c) providing a liquid source separate from the multivalent ion source; and d) combining the foaming source, the multivalent ion source and the liquid source and aerating to produce foam; wherein the multivalent ion source is at least one water soluble multivalent ion source selected from the group consisting of calcium chloride, calcium bromide, calcium lactate, calcium nitrate, calcium acetate, calcium ascorbate and any combination thereof; and wherein the foaming source and the water soluble multivalent ion source are stored as a dry mix together prior to combining with the liquid source.
Patent NZ-568927-A (NZ)
Title: Fungicidal active substance combination comprising trifloxystrobin and pyrimethanil
Inventor: HAUSER-HAHN ISOLDE
IPC: A01N37/50
Filed: 2006-11-27
Abstract: Disclosed is an active compound combination comprising trifloxystrobin (formula (I)) and pyrimethanil (formula (II)). Also disclosed is a method for controlling phytopathogenic fungi, characterized in that an active compound combination as defined above is allowed to act on the fungi and/or their habitat or the plants, plant parts, seeds, soils, areas, materials or spaces to be kept free from them.