baber/WOPTO huggingface dataset:
Patent BR-122019022071-B8 (BR)
Title: composto para inibição de agregação de proteínas envolvidas em doenças ligadas à agregação de proteína e/ou doenças neurodegenerativas e em depósitos de imagem de proteína agregada, uso do mesmo, e kit
Inventor: ANDREI LEONOV
IPC: C07D207/333
Filed: 2009-06-09
Abstract: a presente invenção refere-se a um composto representado pela fórmula (e). a presente invenção refere-se também a um composto representado pela fórmula (e) para uso no tratamento ou na prevenção de doenças ligadas à agregação de proteína e/ou doenças neuro-degenerativas. além disso, a presente invenção refere-se a composições farmacêuticas e de diagnóstico compreendendo o composto da invenção bem como a um kit. ainda, a presente invenção refere-se a um método de depósitos de imagem de proteína agregada. um kit para preparação de um composto detectavelmente marcado da presente invenção é também descrito.
Patent EP-1485057-B9 (EP)
Inventor: MEESE CLAUS
IPC: C07D235/02
Filed: 2003-02-27
Granted: 2006-06-28
Abstract: This invention relates to azaspiro compounds and their use as medications especially for the treatment of chronic, chronic-phlogistic and/or neuropathic pain. Compounds that lend themselves particularly well to the production of analgesics include 1,3-diazaspiro[4.5]decane-2,4-dion and 1,3-diazaspiro[4.5]decane-2,4-dithion.
Patent EP-1583529-B9 (EP)
Inventor: NAG BISHWAJIT
IPC: A61P3/04
Filed: 2004-01-13
Granted: 2012-04-04
Abstract: Novel amino acid phenyl ethers are provided which exhibit activity for the treatment of immunological diseases, inflammation, obesity, hyperlipidemia, hypertension, neurological diseases and diabetes.
Patent EP-1918386-B9 (EP)
Inventor: BAKER JOFFRE B
IPC: C12Q1/68
Filed: 2003-03-12
Granted: 2012-08-08
Abstract: The invention concerns sensitive methods to measure mRNA levels in biopsied tumor tissues, including archived paraffin-embedded biopsy material. The invention also concerns breast cancer gene sets important in the diagnosis and treatment of breast cancer, and methods for assigning the most optimal treatment options to breast cancer patient based upon knowledge derived for gene expression studies.
Patent BE-1026596-B9 (BE)
Title: Schuimstabiliteit
Inventor: BEKKERS AUGUSTINUS CORNELIUS ALDEGONDE PETRUS ALBERT
IPC: C12H1/056
Filed: 2019-09-10
Granted: 2020-06-10
Abstract: De onderhavige uitvinding heeft betrekking op een bier met verminderde hoeveelheden AcHFA. Er is gebleken dat bier met verminderde AcHFA-hoeveelheden verbeterde schuimstabiliteit heeft. De uitvinding verschaft bier met verminderde AcHFA-hoeveelheden, alsook werkwijzen voor het verwijderen van AcHFA uit bier tijdens of na fermentatie, of voor het verwijderen van een precursor voor AcHFA uit wort.
Patent AU-2008341661-B9 (AU)
Title: An erythropoietin mimetic peptide derivatives and its pharmaceutical salt, the preparation and uses thereof
Inventor: SUN CHANGAN
IPC: A61P7/06
Filed: 2008-11-24
Granted: 2013-08-15
Abstract: What is provided is an erythropoietin mimetic peptide derivatives defined as formula (I) and its pharmaceutical salt, the preparation thereof, wherein R1, R2, R3, R4, R5, n1, n2 are defined as described in description. A composition comprising of an erythropoietin mimetic peptide derivatives defined as formula (I) and its pharmaceutical salt. The uses of the derivatives and its pharmaceutical salt, as well as the uses of the composition described above in treatment of diseases characterized by a deficiency of erythropoietin or a low or defective red blood cell population. R1- R2-(CH2)n1-R3-(CH2)n2-R4-R5 (I)
Patent AU-2016353355-B9 (AU)
Title: Aggregating microparticles for therapy
Inventor: YU YUN
IPC: A61K9/50
Filed: 2016-11-11
Granted: 2022-09-29
Abstract: The present invention is a surface treated drug-loaded solid (e.g., non-porous) microparticle that aggregates in vivo to form a consolidated larger particle for medical therapy. In one embodiment, the particles are used for ocular therapy. Processes for producing the surface treated microparticle and injectable formulations which include the surface treated microparticle are also provided. When used in the eye, long-term consistent intraocular delivery can be achieved without disrupting vision and minimizing undesirable inflammatory responses.
Patent DK-179425-B9 (DK)
Title: Fish farming plant with fish extraction
Inventor: FLEMMING OLSEN
IPC: A01K61/00
Filed: 2016-12-06
Granted: 2018-10-30
Abstract: Fish farming plant with a central tank that is at least partially surrounded by one or more fish tanks where at least one of the one or more fish tanks has an inner wall with an inner wall face and an outer wall with an outer wall face, said fish tank having a fish tank width as the distance between the inner wall face and the outer wall face along the extent (azimuth, arc) of the at least one fish tank; the fish farming plant further comprising at least one divider wall with a divider wall width between an inner end and an outer end of the divider wall and configured to span between the inner wall face and the outer wall face; wherein the divider wall width (240) is larger than the fish tank width.
Patent DE-102008023248-B9 (DE)
Title: Ionenquelle mit substrukturiertem Emissionsspalt
Inventor: TEICHERT BERND
IPC: H01J37/08
Filed: 2008-05-13
Granted: 2013-06-06
Abstract: Ionenquelle, insbesondere Anode Layer Ionenquelle, mit einem Gehäuse, mindestens einer im Gehäuse angeordneten Magnetanordnung zur Erzeugung eines Magnetfelds und einer das Gehäuse abdeckenden Kathodenanordnung, wobei die Kathodenanordnung einen Emissionsspalt mit einer endlosen, dem Rand der Magnetanordnung geometrisch ähnlichen Grundform zur Aussendung von Ionen mit einer Zentrallinie und zwei dem Verlauf der Zentrallinie folgenden Rändern aufweist, der eine geschlossene Elektronendrift ermöglicht, dadurch gekennzeichnet, dass der Grundform des Emissionsspalts eine laterale Substruktur zur Vergrößerung der gestreckten Länge des Emissionsspalts überlagert ist.
Patent DE-3237274-C1 (DE)
Title: Brake lining wear indicating device for a disc brake
Inventor: MERZ HORST
IPC: F16D66/02
Filed: 1982-10-08
Granted: 1983-10-27
Abstract: The invention relates to a brake lining wear indicating device for a disc brake, which consists of a measuring pin which is arranged displaceably in a sleeve and which can be placed on the supporting plates for the brake linings in the manner of a depth gauge and whose respective measurement position is indicated by means of markings on the measuring pin and on the sleeve.
Patent DE-3311888-C1 (DE)
Title: Process for obtaining homogeneous antibody-horseradish peroxidase conjugates, the products obtained in the process, and the use thereof
Inventor: LENTFER DIERCK DIPL-CHEM DR
IPC: G01N33/535
Filed: 1983-03-31
Granted: 1984-11-22
Abstract: Homogeneous horseradish peroxidase and horseradish peroxidase conjugates are obtained by chromatography on hydroxyapatite in salt-free solution and subsequent elution with a phosphate gradient.
Patent DE-3406189-C1 (DE)
Title: Folding chair
Inventor: HARDARSON VALDIMAR
IPC: A47C4/04
Filed: 1984-02-21
Granted: 1985-04-25
Abstract: The folding chair (1) is characterised by two pivoting frames (3, 4) which are connected to one another centrally by joints (5, 6), engage in one another and each have an upper bearing frame part (7, 12) for a seat plate (8), a lower frame part (9, 13), and two lateral frame parts (10, 11, 14, 15) which form the chair legs, the seat plate (8) being mounted on the upper frame part (7) of the outer pivoting frame (3) so as to be pivotable into a horizontal and a vertical end position. The lateral frame parts (10, 11) of the outer pivoting frame (3) and one lateral frame part (14) of the inner pivoting frame (4) form continuations (10a, 11a, 14a) which project upwards above the seat plate (8), a backrest (17) which is matched to the shape of the seat plate (8) being mounted at the ends of the continuations (10a, 11a) of the outer pivoting frame (3) so as to be pivotable into a horizontal and a vertical end position, and the end of the continuation (14a) of the lateral frame part (14) of the inner pivoting frame being displaceable by means of a guide tab with two balls in a guide groove machined into the underside of the backrest (17). In the position of use of the chair, the backrest (17) rises slightly towards the rear from its pivot axis. <IMAGE>
Patent DE-3514174-C1 (DE)
Title: Lock for closing orifices in small containers
Inventor: SCHMIDT HANS
IPC: E05B15/16
Filed: 1985-04-19
Granted: 1986-06-19
Abstract: The invention relates to a lock which has a closing cover (1) for closing orifices in small containers. The box-shaped lock case (7) receiving the latch (8) is formed in one piece with the closing cover (1). The latch (8) has laterally projecting holding projections (28, 29) which yield elastically when the latch (8) is introduced into the case (7) and on which bevelled run-on ramps (30) are arranged. These holding projections (28, 29) engage, after assembly, into lateral recesses (11, 12) of the case (7) and form the front stops of the latch (8) held thereby in the case (7). The elastically resilient behaviour of the holding projections (28, 29) is achieved, for example, in that the latch (8) is slotted in the longitudinal direction in the region of its head, so that relatively long spring legs are formed. The one-piece design of the closing cover (1) and lock case (7) results in a reduced number of individual parts, a simplified assembly and a compact construction. <IMAGE>
Patent DE-3529148-C1 (DE)
Title: Device for removing squashed flies from aircraft
Inventor: BERGER ALEXANDER
IPC: B64F5/30
Filed: 1985-08-14
Granted: 1987-04-23
Abstract: A device is proposed for removing squashed flies or the like from aircraft, especially from gliders, which is formed by a film. The film is fitted to the leading edge of the wing before take-off and retains all the squashed flies while being towed to altitude. Once the aircraft has been towed to the desired height, the film is released from the wings, which thereafter are completely clean and smooth so that they achieve their full aerodynamic effect.
Patent DE-3533533-C1 (DE)
Inventor: AMOS WALTER DR
IPC: A46D9/02
Filed: 1985-09-20
Granted: 1986-09-04
Abstract: The present invention relates to a method for rounding the bristle tips of toothbrushes by the action of laser radiation, characterized in that the rounding process is effected in an electrostatic field, thus avoiding the fusion of the individual bristles as well as the formation of a mushroom-like bristle tip.
Patent DE-3540936-C1 (DE)
Title: Intragastric balloon
Inventor: STRICKER REINHARD DR MED
IPC: A61F5/00
Filed: 1985-11-19
Granted: 1986-10-02
Abstract: The invention relates to an intragastric balloon having a filling capacity of 200 to 400 ml for use in therapy of obesity, which is characterised in that the balloon has a sheath, closed or sealed on all sides, of a semipermeable membrane or film which can be degraded after a certain residence time by gastric juice or by body-compatible medication or in the presence of film-degrading substances or cellulose, and in that the balloon is partially filled with a hyperosmolar or hygroscopic substance, the balloon partially filled therewith having a dimension which can still be taken orally and in the activated state after charging having a minimum diameter of 70 mm due to osmosis.
Patent DE-3639189-C1 (DE)
Title: Platen with paper feed for typewriters and similar machines
Inventor: HOFMANN NORBERT
IPC: B41J13/10
Filed: 1986-11-15
Granted: 1988-05-26
Abstract: Known platens are designed as a roller platen or as a drivable band on which the paper to be written on rests. In the case of machines of this type, a separate paper feed must also be provided. In the known devices, a comparatively large amount of friction occurs, thus requiring a powerful drive motor. In contrast, a band is proposed which is guided on the printing side of a carrier in a groove transversely to the paper running direction and, at the same time, a paper feed tray with paper feed rollers is attached to the support in a hinge-like manner. The paper feed rollers are pressed against a drivable paper transporting roller by means of a spring. By this arrangement, simple assembly of a platen with a paper feed is achieved, which consists of few, easily producible parts. Additionally, the platen has a long service life because the impression of each character takes place at a different point on the band.
Patent DE-3825912-C1 (DE)
Title: Process for producing metallic projectile shells which form fragments
IPC: C21D9/16
Filed: 1988-07-29
Granted: 1989-11-02
Abstract: For producing metallic projectile shells which form fragments, predetermined areas of the projectile shell are locally heated by means of a laser beam or electron beam and, after cooling, the resulting weld beads are removed by machining. The material used for the projectile shell is a work-hardened, not thermally hardenable steel of low carbon and nitrogen content.
Patent DE-3830066-C1 (DE)
Title: Device for testing the effectiveness of brakes, especially in motor vehicles
IPC: G01L5/28
Filed: 1988-09-03
Granted: 1989-11-02
Abstract: A device for testing the effectiveness of brakes, especially in motor vehicles, by comparing two simultaneously braked wheels, e.g. the two wheels on one vehicle axle, has a measuring device for the determination of the respective braking force and its conversion into an analog signal, furthermore a calculator which forms a sum signal and a differential signal from the braking force values of the two braked wheels, and finally an indicator which is driven by the computer when the sum signal exceeds a predetermined desired value and, simultaneously, the differential signal does not exceed a predetermined differential limit value. For picking up and comparing the brake signals from the two braked wheels, a bridge circuit is provided whose one measuring input is connected to the brake signals of one wheel and whose other measuring input is connected to the brake signals of the other wheel. An internal relay in the bridge circuit is assigned to each measuring input. The internal relays can be actuated respectively by means of a differential voltage occurring in the bridge circuit and exceeding a predetermined limit value. The internal relays are connected to a signal store which is effectively connected to the indicator.
Patent DE-3943210-C1 (DE)
IPC: E05D7/04
Filed: 1989-12-28
Granted: 1991-06-20
Abstract: The invention relates to a fitting plate (1) for fitting a hinge arm (8) to a body part, having bores for fastening screws (3, 6) and devices (9) for fixing the hinge arm to this. To provide a fitting plate (1) which, whilst being of simple design and having the possibility of simple actuation, allows an adjustment of the height of a hinge arm (8), the fitting plate (1) is mounted in its rear region pivotably relative to the body part about a material or ideal axis, is guided by guide means so as to be pivotable to a limited extent about the pivot axis and is held in adjustable pivoting positions by holding means. 
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Patent DE-4015708-C1 (DE)
Title: Hydraulic IC engine chain tensioner - has liq. outlet limiting closure of sintered metal with incorporated throttling passages
IPC: F16H7/08
Filed: 1990-05-16
Granted: 1991-07-25
Abstract: The hydraulic chain tensioner has a piston, enclosing a pressure chamber in a housing on the piston side away from the chain.  The hydraulic medium is fed into the chamber and run-off through an opening in the piston crown, connected to the chamber by throttling passages, which are confined by the piston wall and arranged in the closure wall used to close the chamber w.r.t.  the chain. The closure (14) is of sintered metal, and the throttling passages (18) are formed in it during sintering up to a passage depth of about 80 micron, using the passage section to control the medium run-off vol.. ADVANTAGE - Compact design with simple and low-cost passage mfr..
Patent DE-4041099-C1 (DE)
IPC: G11B5/09
Filed: 1990-12-21
Granted: 1991-11-21
Abstract: The invention relates to a process and device for recording and reproducing digital data blocks, especially for digital video display, on or from individual tracks on a magnetic tape by the helical-scanning method. The object of the invention is to improve the reproduction quality in special functions, e.g. seeking or time loop. The object is attained in that the test symbols needed for error correction in digital display are recorded on the tape in such a way that test symbols which cannot be assessed in these special functions are located at points on the track at which the greatest interference is likely in the special functions, i.e. when the tape is entering or leaving the magnetic head.
Patent DE-4117717-C1 (DE)
Title: Finely crystalline priming explosive prodn. - by comminuting to specified grain size in non-solvent using high speed stirrer
IPC: C06B21/00
Filed: 1991-05-30
Granted: 1992-12-17
Abstract: Finely crystalline priming explosive (PE) having a grain size below 50, pref. 10-40, esp. 1-10 microns is produced by comminuting PE having a grain size above 100 microns in a non-solvent using a high speed stirrer operating by the stator/rotor principle. The PE is Pb azide, 'tetrazen', Pb nitroresorcinate, Pb picrate, Ag azide and/or diazodinitrophenol. The non-solvent is water and/or EtOH. The ratio non-solvent: PE is 100-5:1. The stirring rate is 1,000 rpm. to ultrasound. ADVANTAGE - Provides highly efficient process.
Patent DE-4211602-C1 (DE)
IPC: H01R25/00
Filed: 1992-04-07
Granted: 1993-06-03
Abstract: A low-voltage electrification device for built-in furniture or interior structures is described having large-area conductors (2) which are inserted in an insulating panel structure (1), are preferably in the form of a grid and are arranged at different levels. Input devices (3, 4) and output devices (5, 6) are provided in the panel structure (1) for the supply voltage input and output. This results in an electrification device which is easily accessible at any point.
Patent DE-4302465-C1 (DE)
Title: Appts. for producing dielectrically-hindered discharge - comprises gas-filled discharge space between two ignition voltage-admitted electrodes
Inventor: NEFF WILLI DR
IPC: H01S3/0971
Filed: 1993-01-29
Granted: 1994-03-10
Abstract: Appts. for producing a dielectrically-hindered discharge (1) has a gas-filled discharge space (2) between two ignition voltage-admitted electrodes (3,4) from which at least one is sepd. from the space (2) by a dielectric (5). The novelty is that at least one electrode (3 is a voltage-excited plasma in a gas, whose pressure is lower than the gas pressure in the discharge space (2). USE/ADVANTAGE - To induce chemical reactions, to excite dye lasers; and to homogenise middle and high pressure plasmas in laser and on plasma-supported material deposition from the gas phase (claimed). Compact distribution of the filaments or homogenisation of the discharge in the gas-filled discharge space is achieved.
Patent DE-4314264-C1 (DE)
Title: Device for cleaning the rims of motor vehicle wheels
Inventor: GOETZ ELMAR
IPC: B60S3/04
Filed: 1993-04-30
Granted: 1994-10-27
Abstract: A method and a device for cleaning the rims (10) of motor vehicle wheels using a sandblasting device (34) is described, the said sandblasting device (34) being connected to a pressurised gas source (42). The rim (10) to be cleaned is made to rotate by means of a first drive device (28) and the sandblasting device (34) is held at a distance from the rim (10) to be cleaned and is moved linearly in the radial direction of the said rotating rim (10) by means of a second drive device (88). <IMAGE>
Patent DE-4315105-C1 (DE)
Title: Method and arrangement for the angular adjustment of a line scanning device
Inventor: HIPPENMEYER HEINRICH DIPL ING
IPC: G06K7/10
Filed: 1993-05-06
Granted: 1994-09-01
Abstract: The adjustment of a line scanning device having a housing 11 is carried out by first aligning the housing 11, fastened on a universal joint 24, by means of a marked scanning light beam 12, onto a mark 18 on a test body 16, any angular offset between the scanning line 15 and a marking line 17 on the test body 16 being then eliminated by means of tilting the housing 11. <IMAGE>
Patent DE-4335922-C1 (DE)
Title: Device for cleaning the tooth interstices
Inventor: FISCHER THOMAS
IPC: A61C15/04
Filed: 1993-10-21
Granted: 1995-04-13
Abstract: In order to apply the force which is needed to use dental floss to clean the tooth interstices, it is necessary to bring the fingers of one hand into the mouth in order to tension the floss. For many people this is difficult and unpleasant. The device serves to hold and tension the dental floss. The floss 4 is in this case pretensioned about a frame 1 and can be tensioned by pressing with the fingers on the grip part 3. <IMAGE>
Patent DE-4336533-C1 (DE)
Title: Guide device for a ring rail of a ring-spinning or ring-twisting machine
Inventor: MANN PETER
IPC: D01H1/36
Filed: 1993-10-26
Granted: 1995-02-02
Abstract: The invention relates to a guide device for a ring rail of a ring-spinning or ring-twisting machine, which has a guide bush 1 which is fixed to the machine and in which a lifting rod 3 guiding the ring rail 4 is guided, at least via end bearing points, so as to be movable up and down. The guide bush 1 is surrounded by a tube 5 which is fixedly connected to the lifting rod 3 and which has an axially extending slot 6 for the passage of a web 7 retaining the guide bush 1 on the machine. <IMAGE>
Patent DE-4338495-C1 (DE)
Title: Device for connecting a wheel to a wheel axle
Inventor: TOLGES WERNER
IPC: B60B3/14
Filed: 1993-11-11
Granted: 1995-04-13
Abstract: Device for connecting a wheel rim to a wheel axle, comprising a slotted bearing sleeve which can be inserted into the hub of the wheel rim and has the purpose of receiving the wheel axle. The wheel axle has a groove with which the bearing sleeve can be brought into engagement, the bearing sleeve (5) which has a radially movable locking element (8) is connected to a control element (4) which can be moved axially in relation to the bearing sleeve (5) and the locking element (8) is capable of being moved into the groove (3a) of the wheel axle (3) by means of the control element (4). <IMAGE>
Patent DE-4400352-C1 (DE)
Inventor: BATSFORD STEPHEN PROF DR
IPC: C07K16/46
Filed: 1994-01-08
Granted: 1995-05-18
Abstract: The object of the present invention are novel chimeric antibodies of the general formula Y1-Z-Y2 in which Y1 is a first non-human immunoglobin of known specificity, Y2 is a second unspecific human immunoglobin of the IgX class and Z is a covalent bond, their production and their use in serological-immunological diagnosis.
Patent DE-4410355-C1 (DE)
Title: House installation unit for gas pipes
IPC: F16L5/02
Filed: 1994-03-25
Granted: 1995-06-14
Abstract: The unit has a steel pipe section which can be laid through the building floor (17) and which is formed by a flexible steel hose (5). The hose has short pipes (2,4,6) at the ends to connect with the connection unit inside (18) the building and a plastics pipe (1) outside (16) the building. The short end pipes have radial collars (7,8) connected together by a steel corrugated tube (9) which encloses the steel hose at a distance. The short pipe inside the building is protected from displacement on the building floor.
Patent DE-4419672-C1 (DE)
Title: Painting roller for walls etc. with angled bracket in handle
Inventor: DECK FRITZ
IPC: B05C17/02
Filed: 1994-06-07
Granted: 1995-08-17
Abstract: The angled bracket (3) is fitted with a rotary roller body (1) with a free front side. The roller body carries a layer (5) of resilient, absorption material for the paint, while a swivel lever (7) is located on the bracket, whose end carries a trapezoidal, lateral protective plate (2) swivelable from its working position into one opposite the roller front side. Both longitudinal edges of the protective plate are fitted with flat brushes (15) for forming paint boundary lines. In the protective plate working position the flat brushes slightly protrude over the roller dia. They enclose an acute angle with the protective plate.