baber/WOPTO huggingface dataset:
Patent DE-69730352-T2 (DE)
Inventor: INOUE KAZUHIRO
IPC: A61K47/48
Filed: 1997-06-05
Granted: 2005-09-08
Abstract: A method for preparing a drug complex in which a polysaccharide derivative having carboxyl groups and a residue of a drug compound are bound to each other by means of a spacer comprising an amino acid or a spacer comprising peptide-bonded 2 to 8 amino acids, or a drug complex in which a polysaccharide derivative having carboxyl groups and a residue of a drug compound are bound to each other without the spacer, characterized in that an organic amine salt of the polysaccharide derivative having carboxyl groups is reacted with the drug compound or the spacer bound to the drug compound in a non-aqueous system. The reaction between the polysaccharide derivative having carboxyl groups and the drug compound bound with the spacer or the like can be carried out in high yields, and when a drug compound having a lactone ring is subjected to the reaction, side reactions can be reduced.
Patent DE-69731767-T2 (DE)
Inventor: ETIEVANT CLAUDE
IPC: H01M8/06
Filed: 1997-12-23
Granted: 2005-11-24
Abstract: One of these devices comprises: a reaction with cold plasma (10b), for producing the reforming of a primary mixture consisting of fuel gas (hydrocarbon or alcohol), as well as oxygen and/or water vapor, thus producing a secondary mixture containing in particular hydrogen, carbon dioxide and carbon monoxide; an intake piece (18) for mixing these constituents, co-operating with a burner (42) and an associated combustion chamber (40) to bring the resulting primary mixture to a high temperature, before it is introduced into the reaction chamber (10a); a ring-shaped chimney (48) enclosing this chamber for maintaining it at a relatively high temperature; a high frequency alternating high voltage source (58), modulated by brief periodical low frequency pulses and electrodes (62-66) for generating silent discharges, in the reaction chamber (10b) thus generating a cold plasma producing a high chemical reactivity to the gas mixture present; a membrane (12) with high selective permeability for extracting the nascent hydrogen, arranged between the chamber (10b) and a chamber for collecting the hydrogen (14); a thermal insulating sheath (50) enclosing the whole set. The invention is applicable to PEM type fuel cells, fitted on electric vehicles or on portable generator set.
Patent DE-69732847-T2 (DE)
Inventor: ESMON T
IPC: C12P21/02
Filed: 1997-11-07
Granted: 2006-04-13
Abstract: The promoter of the EPCR gene has been isolated from both murine (SEQ. ID No. 1) and human (SEQ. ID No. 2) genomic libraries. The promoter includes a region (nucleotides 3130 to 3350 of SEQ. ID No. 1 which affects selective gene expression in endothelial cells), and a region (nucleotides 2270 to 2840 of SEQ. ID No. 1) which affects selective gene expression in large vessel endothelial cells, as compared to expression in all endothelial cells. The EPCR promoter contains a thrombin responsive element, CCCACCCC (SEQ. ID No. 3), (murine, nucleotides 3007 to 3014 SEQ. ID No. 1 and human, nucleotides 2722 to 2729 SEQ. ID No. 2). The EPCR also contains a serum response element (nucleotides 2990 to 3061 of SEQ. ID No. 1). The regulatory sequences present in the EPCR promoter can be used for thrombin or serum controlled recombinant gene expression specific to either all endothelial cells or primarily endothelial cells of large vessels. Therapeutic strategies include the use of the minimal promoter for expression of therapeutic agents during times of increased thrombin/platelet activation or regional trauma in all endothelial cells or the use of the large vessel specific promoter for regional specific expression in the endothelial cells of large vessels for use in delivery.
Patent DE-69810662-T2 (DE)
Inventor: MAUMUS JEAN-PIERRE
IPC: C21D9/32
Filed: 1998-12-15
Granted: 2003-11-13
Abstract: The loader device is made of a thermostructural composite material and comprises a base (20), a loading pole (30) secured to the base and extending at least over the full height of the loader device, and a plurality of loading trays (40) each provided with a central passage through which the loading pole can pass. Each loading tray carries a plurality of spacers (50) enabling the trays to be mounted in succession at predetermined intervals, each tray carrying the same number of spacers which are in alignment so that after the trays have been assembled the spacers make up load-carrying columns extending over the height of the loader device, and at least one of the spacers carried by each tray has a disposition and/or a size that differs from the other spacers carried by the same tray so as to enable the trays to be indexed during assembly. Each tray (40) has means (45) for positioning parts at predetermined locations.
Patent DE-69810864-T2 (DE)
Inventor: FLEGO CRISTINA
IPC: C10G45/60
Filed: 1998-10-09
Granted: 2003-10-16
Abstract: Process for the hydroisomerization of long-chain n-paraffins which comprises isomerizing n-paraffins having a number of carbon atoms higher than 15 in the presence of hydrogen and a hydroisomerization catalyst which comprises:   a) a carrier of acid nature consisting of a silica and alumina gel amorphous to X-rays, with a molar ratio SiO2/Al2O3 ranging from 30/1 to 500/1, and having a surface area ranging from 500 to 1,000 m<2>/g, a porosity ranging from 0.3 to 0.6 ml/g and a pore diameter within the range of 10-40 Angstrom; b) a mixture of metals belonging to groups VIB and VIII deposited on the carrier in an overall quantity ranging from 2 to 50% by weight of the total (a) + (b).
Patent DE-69834319-T2 (DE)
Inventor: MILLER MORTEN
IPC: C12Q1/34
Filed: 1998-01-30
Granted: 2007-04-12
Abstract: A method for selectively determining a fungal biomass by detection of a fungal enzymatic activity that is present in substantially all fungal species, such as enzymes involved in chitin metabolism (chitinase, chitin synthase, chitosanase, N-acetyl-glucosaminidase and beta-N-acetylhexosamidase). The invention can be used for detecting a fungal biomass in environmental samples, food products, plant material, building materials, industrial fungal cultures or sample from a human being or animal including blood samples. In particular, 4-methylumbelliferyl-N-acetyl-beta-D-glucosaminide is used as substrate for beta-N-acetylhexosamidase (EC 3.2.1.52). This enzyme activity correlates with the amount of fungal biomass present in a sample.
Patent DE-69837597-T2 (DE)
Inventor: KOYAMA NOBUTO
IPC: C07C45/60
Filed: 1998-02-26
Granted: 2007-12-27
Abstract: A compound represented by the following formula ÄIÜ or an optically active substance or a salt thereof. <CHEM> (In the formula, a bond shown by a dotted line in the five-membered ring means that said five-membered ring may be any of a cyclopentene ring having a double bond and a cyclopentane ring where said bond is saturated and, in the case of a cyclopentene ring, X is OH, Y is =O and Z is H while, in the case of a cyclopentane ring, X is =O, Y is OH and Z is OH. R is a residue after removal of an SH group from the SH-containing compound.)
Patent DE-69839277-T2 (DE)
Inventor: DONOVAN WALTER E
IPC: G06T15/00
Filed: 1998-01-28
Granted: 2009-04-30
Abstract: A method and apparatus for chroma keying filtered textures are provided. Chroma keying is performed which replaces the input texel color with a new color if the input texel color matches the chroma color. The chroma key circuitry keeps the input texel color and sets the alpha component to 1 if the input texel color does not match the chroma color. The chroma keyed texels are filtered using bilinear filtering. The color components of the filtered texels are fogged using a fog factor, a fog color, and the alpha component of the filtered texel. The fogged and filtered signal is blended with a background color to produce an output color for the texels.
Patent DE-69900643-T2 (DE)
Inventor: BILLINGS ALEC
IPC: G06F17/10
Filed: 1999-03-02
Granted: 2002-08-14
Abstract: The present invention relates to nonlinear systems and methods of design thereof in the frequency domain. Typically, conventional linear filter design involves attenuating signals at frequencies which are not of interest and dissipating the energy at those frequencies as, for example, heat or sound. However, in more systems, it is not always convenient to design a linear system or design a system solely with energy attenuation in mind. Therefore, the present invention provides a nonlinear system and method of design thereof in the frequency domain which can be used to transfer energy at a first pre-determinable frequency, or frequency range, to a second pre-determinable frequency, or frequency range. Using the method of the present invention a nonlinear system can be developed which can meet given energy transfer requirements or a nonlinear system can be designed which can alter the transfer function of an existing nonlinear or linear system.
Patent DE-69901270-T2 (DE)
IPC: B23C5/10
Filed: 1999-01-19
Granted: 2002-11-21
Abstract: A special geometry for helical cutting tools comprises a cutting face generated by a right or left helix. Preferred Features: The tool has a X-TREM (RTM) PVD coating based on titanium, aluminum and nitrogen with a hardness of 3700 HV.
Patent DE-69909277-T2 (DE)
Inventor: KOK JAN
IPC: C09K21/14
Filed: 1999-04-09
Granted: 2004-05-19
Abstract: The invention relates to methods for drilling wells into subterranean formations containing oil, gas or other minerals for the purpose of extraction and production of said minerals. In particular, the invention relates to drilling fluids used in such methods and the use of starch in such fluids. The invention provides a method for drilling a well using a drilling fluid comprising a starch obtained from tubers or roots, said starch containing virtually only amylopectine molecules. In a preferred embodiment of the invention, said starch is derived of a genetically modified amylose-free potato.
Patent DE-69912502-T2 (DE)
Inventor: BOLLE THOMAS
IPC: B27K3/36
Filed: 1999-03-10
Granted: 2004-09-23
Abstract: The invention relates to a method of protecting wood against light-induced degradation by treatment with a stain or impregnation which penetrates the surface of the wood comprising     a) at least one organic solvent;   b) a hindered amine compound of formula I or II <CHEM>  where   G1 and G2 are independently alkyl of 1 to 4 carbon atoms or are together pentamethylene, Z1 and Z2 are each methyl, or Z1 and Z2 together form a linking moiety which may additionally be substituted by an ester, ether, hydroxy, oxo, cyanohydrin, amide, amino, carboxy or urethane group,   E is oxyl or hydroxyl,   X is an inorganic or organic anion, and   where the total charge of cations h is equal to the total charge of anions j.
Patent DE-69914976-T2 (DE)
Inventor: LANDROT ALAIN
IPC: B61F3/08
Filed: 1999-07-02
Granted: 2004-07-29
Abstract: The bogie consists of a structure (2) or chassis of a composition material containing at least one fixed inner rigid support with fixings (50) for functional components (53). Each support is in the shape of a hollow C-section or double C-section rail (20b) with fixings in the form of sliders with threaded holes (51) for bolts (52). The composition structure is moulded with the rigid supports inside it.
Patent DE-69924185-T2 (DE)
Inventor: KARI HANNU
IPC: H04L9/32
Filed: 1999-01-11
Granted: 2006-03-23
Abstract: An access point (GGSN) from a mobile communications system to an external system is selected (3) at a service node (SGSN) of the mobile communications system based on at least two or three grounds of selection: the subscription data of a mobile subscriber stored in the mobile communication system or an access point selection data given by a user in a service request (1), or on other grounds. The serving node sends to the access point (GGSN) selected a further service request (4) which includes indication of the grounds of the selection, i.e. whether the access point is selected by subscription, by a user, or based on any other grounds. Thereby the access point is able to distinguish and accept service requests in which the rights of the user are already assured by the subscription, without any security problems. When the request is based on the selection of the access point by the user, or on any other insecure grounds, the access point is able to make any further actions to ensure the security. These further actions may include rejection of the service request.
Patent HU-E031760-T2 (HU)
Title: Dietary supplements containing extracts of cinnamon and methods of using same to enhance creatine transport
Inventor: MILLER PETER
IPC: A01N65/00
Filed: 2005-04-11
Abstract: Materials derived from cinnamon can be administered orally to humans or animals for the purpose of controlling blood glucose as well improving glucose tolerance. Controlling glucose metabolism is essential for those with impaired glucose metabolism as is the case for those with Type II diabetes where insulin function is not properly functioning. Such administration can also be used for the purpose of enhancing nutrient transport for purposes of athletic performance and controlling bodyweight and body fat levels. Similarly related, such administration can also be used for the purpose of enhancing creatine transport into excitable tissues such as skeletal muscle. The material can be administered as extracts of cinnamon and can be administered in a variety of ways including capsules, tablets, powdered beverages, bars, gels or drinks.
Patent HU-E028190-T2 (HU)
Title: Pharmaceutical composition containing SAA for use in the treatment of acute and chronic dysregulated inflammatory diseases or conditions
Inventor: SANDER LEIF ERIK
IPC: A61K38/17
Filed: 2010-03-22
Abstract: The present invention describes a novel intervention strategy for the treatment of dysregulated inflammations by using hepatic acute phase proteins serum amyloid A (SAA), CXCL-1/GRO-1/KC or C-reactive protein (CRP) or neutralizing antibodies to these proteins as diseases modulators. The said proteins are to be used as pharmaceutical compositions in the treatment of conditions and diseases characterized by dysregulated inflammations. Besides direct anti-inflammatory as well as host-defensive effects, a hitherto unrecognized regulation of myeloid-derived suppressor cells (MDSC) is uncovered. Myeloid derived suppressor cells seem to be key regulators of inflammatory responses during sepsis and thus represent a valuable target for treatment of these disorders. In a further aspect, the present invention concerns the use of effective amounts of the above identified active agents for activation and mobilisation of MDSC for treatment of excessive dysregulated inflammatory diseases. Further the use of neutralizing antibodies or small molecular inhibitors to treat conditions of suppressed inflammatory responses such as cancer is claimed. The present invention proposes the use of blocking antibodies to SAA, CXCL-1/GRO-1/KC and CRP to prevent MDSC activity and thus boost anti-tumor immune responses in cancer.
Patent HU-E025369-T2 (HU)
Title: Anti-CD38 human antibodies and uses therefor
Inventor: TESAR MICHAEL
IPC: C07K16/28
Filed: 2005-02-07
Abstract: The invention provides a human or humanized anti-CD38 antibody or functional fragment thereof, wherein said antibody or functional fragment thereof is able to mediate killing of a CD38+ target cell by ADCC with an at least five-fold better efficacy than chimeric OKT10 under the same or substantially the same conditions when a human PBMC cell is employed as an effector cell, wherein said CD38+ target cell is selected from the group consisting of LP-1 and RPMI-8226, and wherein the ratio of effector cells to target cells is between about 30:1 and about 50:1. The invention further provides a human or humanized anti-CD38 antibody or functional fragment thereof, wherein said antibody or functional fragment thereof is able to mediate killing of a CD38-transfected CHO cell by CDC with an at least two-fold better efficacy than chimeric OKT10 under the same or substantially the same conditions. The invention further provides a human or humanized anti-CD38 antibody, wherein said antibody binds to an epitope of CD38 comprising one or more amino acid residues of amino acid residues 1 to 215 of CD38. Nucleic acids encoding the antibodies of the invention as well as therapeutic uses of the antibodies are also provided.
Patent HU-E035354-T2 (HU)
Title: Smart fenestration product system having remote control
Inventor: HADZISELIMOVIC MIRALEM
IPC: E06B9/68
Filed: 2014-01-28
Abstract: This invention belongs to the area of access control, remote control, sensor systems and intelligent windows and doors system management via a mobile phone, web-based interface or with the use of short-range contactless technology. The proposed system and smart home fenestration product management and control procedure enables access control and management remotely with the use of a mobile phone, tablet or a web interface. The proposed system comprises several components: control electronics with autonomous photovoltaic power supply, built into fenestration product (window or door) frame, and with radio-frequency (RF) transmitter/receiver module; central control unit with radio-frequency transmitter/receiver module and wireless or wired network connection Wifi or LAN; mobile application for system management running on any mobile phone, tablet or another mobile device, or a web application for system management, running in any web browser on any device that enables web browsing.
Patent MD-3313832-T2 (MD)
Inventor: BENNETT FRANK
IPC: C07D471/04
Filed: 2016-06-24
Abstract: Prezenta invenţie se referă la compuşi cu formula I care sunt inhibitori ai metalo-β-lactamazei:şi săruri acceptabile farmaceutic ale acestora, în care Z, RA, X1, X2 şi R1 sunt aşa cum au fost definiţi. Prezenta invenţie se referă de asemenea la compoziţii ce cuprind un compus al invenţiei cu inhibitor al metalo-β-lactamazei sau o sare acceptabilă farmaceutic a acestuia, precum şi la un purtător acceptabil farmaceutic, fiind opţional în combinaţie cu un antibiotic beta-lactamic şi/sau cu un inhibitor beta-lactamic. De asemenea, invenţia se referă la metode de tratare a unei infecţii bacteriale, cuprinzând administrarea la un pacient a unei cantităţi farmaceutic eficiente a unui compus al invenţiei, în combinaţie cu o cantitate farmaceutic eficientă a unui sau mai multor antibiotice β-lactam şi opţional în combinaţie cu unul sau mai mulţi compuşi cu inhibitor al metalo-β-lactamazei. Compuşii invenţiei sunt folositori la depăşirea rezistenţei antibiotice în cadrul metodelor descrise.
Patent TR-200001246-T2 (TR)
Title: Anti-CD40L bileşikleri ile lupus nefritis tedavisi
Inventor: KALLED SUSAN L
IPC: A61K45/00
Filed: 1997-12-31
Abstract: Immün kompleks hastaliklarla baglantili nefriti anti-CD40L bilesikleriyle tedaviye yönelik yöntemler öngörülmektedir. Teskil örneklerinden birinde immün kompleks hastaligi olan böbrek allografti yapilmis bir hastaya, nakil yapilan böbrek içinde immün kompleks glomerülonefrit olusmasini önlemek için anti-CD40L bilesikleri verilmistir.
Patent DE-602004001093-T2 (DE)
Inventor: NISHIHARA SHIGEYOSHI
IPC: B61B13/12
Filed: 2004-06-23
Granted: 2006-12-28
Abstract: The conveyor has a sensor sensing whether frictional wheels (30) are in contact with any one frictional surface of carriers. Control boxes (24) control associated brakeless motor (29) to start rotating the associated wheels in contact with one surface when the forward next wheel gets free of the surfaces and to stop driving the friction wheel after getting free of the surfaces, based on signal from the sensor.
Patent DE-602004003342-T2 (DE)
Inventor: WALKER K
IPC: G02B6/44
Filed: 2004-02-10
Granted: 2007-06-14
Abstract: The subject invention pertains to a method for high speed, continuous manufacture of graded refractive index polymer optical fiber. The subject fiber material may be organic or perfluorinated. The subject method can include first forming energy activatable prepolymer compositions containing additives. The prepolymer compositions can be extruded at low temperature through a multi-annular die and surrounded by a co-extruded concentric melt stream which forms a tube with good structural integrity. The prepolymer compositions contained in the tube can be maintained at a temperature for a time sufficient to form the desired graded index profile. Energy can be delivered to the prepolymer compositions which can cause an irreversible chemical transformation and forms a mechanically and thermally stable polymer. A continuous process of thermal annealing of the fiber can be used to minimize residual stress. Multiple fibers may be produced simultaneously in a variety of physical configurations.
Patent DE-602004003684-T2 (DE)
Inventor: ZHONG ZHUN
IPC: H04W52/02
Filed: 2004-02-23
Granted: 2007-10-04
Abstract: A wireless device and method may be used to receive messages. The wireless device may include, among other things, a receiver, a processor, and a memory. The processor may be configured to determine whether a received message includes a mobile device identification. The processor may perform the determination periodically, for example, during a transmit time interval (TTI). If at least one of the received messages includes a mobile device identification and information indicating that data is to be sent to the wireless device, the wireless device may initiate receiving data in accordance with the information. If a received message does not include any mobile device identification, the wireless device may initiate discontinuous reception. The discontinuous reception may be performed until the next TTI.
Patent DE-602004003910-T2 (DE)
Inventor: WALLIS JOHN
IPC: H01L21/20
Filed: 2004-02-16
Granted: 2007-05-16
Abstract: A buffer structure comprising a compositionally graded layer of a nitride alloy comprising two or more Group IIIB elements, for example La, Y, Sc or Ac, is used to modify a silicon substrate to produce a universal substrate on which a range of target materials, for example GaN, may be deposited to produce semiconductor devices for electronic and optical applications. The resulting lattice parameter L varies with thickness T through the structure.
Patent DE-602004004239-T2 (DE)
Inventor: BUCKLEY ADRIAN
IPC: H04L12/56
Filed: 2004-02-27
Granted: 2007-11-15
Abstract: Apparatus, and an associated method, for facilitating selection of a network with which a roaming mobile node communicates to effectuate a packet data communication service. A database is maintained at the mobile node indicating radio access networks together with their communication capabilities. The database is dynamically maintained and updated, if needed. When the mobile node roams and packet communications are to be effectuated, the database is accessed to determine with which of available radio access networks through which the mobile node should communicate.
Patent DE-602004005737-T2 (DE)
Inventor: OVEREND ANDREW STUART
IPC: C09D11/00
Filed: 2004-10-19
Granted: 2007-12-27
Abstract: Non-aqueous, radiation-curable inks comprising pigment, dispersant and a liquid carrier, wherein the pigment has an acid value greater than 8 mg of NaOH per gram of pigment. The inks are particularly suitable for use in ink jet printers.
Patent DE-602005000205-T2 (DE)
Inventor: BILLARD SYLVAIN
IPC: A01D57/20
Filed: 2005-01-14
Granted: 2007-08-30
Abstract: The machine has a tipper (11) and a cross-arm (12) connected to a chassis (10) and the tipper using pivot articulations (14, 15), respectively. A cutting mechanism (4) cuts a standing crop and is connected to the cross-arm using a pivot articulation (16). A conveying attachment (7) laterally moves the cut crop and is connected to the tipper to rotate with respect to the chassis around the articulation (14) jointly with the mechanism.