baber/WOPTO huggingface dataset:
Patent UY-24498-A1 (UY)
Title: Lactama derivados de bencilo y bencilideno como agonistas y antagonistas selectivos de receptores 5-ht1a y 5-ht1d
Inventor: HOWARD HARRY R
IPC: C07D217/24
Filed: 1997-03-21
Abstract: La presente invención se refiere a derivados de lactama, a procedimientos y a intermedios para su preparación, a composiciones farmacéuticas que los contienen y a su uso en medicina. Los compuestos de la presente invención incluyen agonistas y antagonistas selectivos de receptores de serotonina 1 (5-HT1), específicamente, de uno o de los dos receptores 5-HT1A y 5-HT1D. Son útiles en el tratamiento o prevención de la migrana, depresión y otros trastornos para los que están indicados los agonistas o antagonistas de 5-HT1. Un compuesto de la fórmula (I) o una sal farmacéuticamente aceptable del mismo, en la que: R1 es un grupo de la fórmula G1, G2, G3, G4 ó G5, representados como figura 2, en las que E es oxígeno, azufre, SO o SO2; R2 es hidrógeno; R3 es (CH2)mB, donde m es 0, 1, 2 o 3 y B es hidrógeno, fenilo, naftilo, furilo, tienilo, piridilo, pirimidilo, tiazolilo, pirazolilo, isotiazolilo, oxazolilo, isoxazolilo, pirrolilo, triazolilo, tetrazolilo, imidazolilo, y donde cada uno de los grupos arilo y heteroarilo anteriores pueden estar opcionalmente sustituidos; Z es CR4R5, donde R4 y R5 se seleccionan independientemente entre hidrógeno, alquilo y trifluorometilo; ó Z puede ser furilo, tienilo, piridilo, pirimidilo, tiazolilo, pirazolilo, isotiazolilo, oxazolilo, isoxazolilo, pirrolilo, triazolilo, tetrazolilo, imidazolilo y donde dos miembros adyacentes en el anillo de Z también son miembros del anillo A; X es hidrógeno, cloro, fluoro, bromo, yodo, ciano, alquilo, hidroxi, trifluorometilo, alcoxi, Sog-alquilo donde g es 0, 1 o 2, CO2R10 ó CONR11R12; n es 1, 2, 3 o 4; y la línea discontinua indica un doble enlace opcional; con la condición de que n tiene qe ser 1 cuando Z es un grupo heteroarilo. Por ejemplo: 3-(2-(4-metilpiperazin-1-il)-bencilideno)-1,3-dihidro-indol-2-ona. Estos compuestos son útiles en un mamífero como agentes psicoterapéuticos, como ser en depresión, trastornos de ansiedad generalizada, fobias, pánico, Alzheimer, Parkinson, entre otros; para hipertensión disfunción sexual, trastornos de alimentación, obesidad, cefaleas, migranas, trastornos endocrinos, trastornos del tracto gastrointestinal, entre otras.
Patent UY-27970-A1 (UY)
Title: Verificacinn biometrica segura de identificación
Inventor: SAITO TAMIO
IPC: G06K19/077
Filed: 2003-09-10
Abstract: Tarjeta de identificación de alta seguridad que incluye una memoria integrada para almacenamiento de datos biométricos y un sensor integrado para capturar los datos biométricos directamente. Procesador integrado en la tarjeta que realiza una operación de correspondencia para verificar que los datos biométricos capturados se corresponden con los datos biométricos almacenados en forma local. Solo en caso de obtenerse una correspondencia positiva, se realiza transmisión de datos desde la tarjeta para verificación adicional y/o para otros procedimientos. La tarjeta puede utilizarse para permitir la comunicación con una red de transacciones o para obtener acceso físico a un área de seguridad.
Patent UY-29641-A1 (UY)
Title: Derivados de isoquinolina
Inventor: HOFMEISTER DR ARMIN
IPC: C07D217/22
Filed: 2006-06-29
Abstract: La invención se refiere a derivados de isoquinolina sustituidos en posición 6 con piperidinilo de la fórmula (I) útiles para el tratamiento y/o prevención de enfermedades asociadas con Rho-cinasa y/o la fosforilación mediada por Rho-cinasa de la fosfatasa de la cadena ligera de miosina, y a composiciones que contienen tales compuestos.
Patent UY-30331-A1 (UY)
Title: Composicion de una bebida antioxidante de jugo gaseoso
Inventor: VICTORIA REID
IPC: A23L33/15
Filed: 2007-05-07
Abstract: Una bebida de jugo gaseoso que comprende agua carbonatada, concentrado de jugo, vitaminas C y E antioxidantes, extracto de té verde y extracto se semilla de uva. La bebida puede ser endulzada con edulcorantes naturales, artificiales o una combincacion de ambos. La bebida de jugo gaseoso de la invencion proporciona una forma refrescante y deliciosa de proporcioanr antioxidantes importantes para l salud corporal.
Patent UY-30450-A1 (UY)
Title: Aplicacinn de alta frecuencia de terapia con toxina botulenica
Inventor: DRESSLER DIRK
IPC: A61K9/08
Filed: 2007-06-28
Abstract: La presente invencnn se refiere a mctodos para tratar enfermedades y trastornos mediante la administracinn de una composicinn que contiene al componente neurotnxico de un complejo de toxina Clostridium botulinum, en donde la composicinn carece de cualquier otra proteena del complejo de toxina Clostridium botulinum y, en donde la composicinn se administra en intervalos cortos y/o en dosis elevadas.
Patent UY-31234-A1 (UY)
Title: Inhalador de polvos
Inventor: METZGER BURKHARD P
IPC: A61J3/00
Filed: 2008-07-17
Abstract: Inhalador con capacidad de uso mejorada para la inhalacion de medicamentos en forma de polvo a partir de cápsulas, las cuales son introducidas, antes del uso, en un portacápsulas dispuesto en el inhalador. El paciente puede pulsar un organo de accionamiento después de colocar la cápsula en el portacápsula, el cual es desplazable de una posicion de reposo a una posicion de movimiento y así actua con al menos una aguja que empuja el portacápsulas. Con ayuda de al menos una aguja se pincha la cápsula y se libera el medicamento.
Patent UY-31660-A1 (UY)
Title: Sistemas de administración de drogas que contienen estradiol
Inventor: HOLLER THOMAS
IPC: A61K9/70
Filed: 2009-02-13
Abstract: Sistemas de administración de drogas en la forma de películas delgadas solubles en agua (obleas), que contienen estradiol, o derivados del mismo, en cantidades bajas. Las obleas de la presente invención son adecuadas para tratar, aliviar o prevenir una condición física en un mamífero hembra causada por niveles endógenos de estrógeno insuficientes.
Patent ES-171373-A1 (ES)
Title: UN PROCEDIMIENTO PARA IMPEDIR LA REACCIoN INDESEABLE DE REVELADORES DIFERENCIALES AL CONECTAR APARATOS INDUCTIVOS
Filed: 1945-10-26
Abstract: Procedimiento para impedir la reacción indeseable de relevadores diferenciales al conectar aparatos inductivos a cuya protección están destinados caracterizándose porque por medio de ondas de corriente con frecuencia de red extraña contenidas en la intensidad de conexión se impulsa un sistema mecánico de oscilación sintonizado a la onda respectiva y se emplea para el bloqueo del relevador diferencial.
Patent ES-187459-A1 (ES)
Title: Perfeccionamientos en los transportes y descargadores por gravedad, por inercia, accionados a mano y por correa, accionados por fuerza motriz, con rodillos de puntos de acerc
Filed: 1949-03-15
Abstract: Perfeccionamientos en los transportadores y descargadores por gravedad por inercia accionados a mano y por correa accionados por fuerza motriz con rodillos de puntos de acero caracterizados esencialmente por unos rodillos con puntas de acero montados en unos bastidores formados por perfiles laminados.
Patent ES-195478-A1 (ES)
Title: Un mecanismo de cerradura o cerrojo
Filed: 1950-11-21
Abstract: Mecanismo de cerradura o de seguro que comprende una o más chavetas de seguro movibles axialmente que están destinadas a entrar hasta una profundidad predeterminado en perforaciones correspondientes de una llave con preferencia en forma de cinta; caracterizado porque las chavetas de seguro están dispuestas para ser movidas hasta encajar en las perforaciones de la llave por la llave propiamente dicha al insertarla en el ojo de la cerradura.
Patent ES-199201-A1 (ES)
Title: Un aparato para tratar carbones de fibras
Filed: 1951-08-11
Abstract: Un aparato para tratar cordones de fibras que incluye un par de elementos rotativos en contacto lateral entre sí teniendo al menos uno de dichos elementos una superficie elástica deformable y estando al menos uno de dichos elementos provisto de mediso cortadores con lo cual los elementos rotativos cogerán un cordón que pasa entre ellos y al mismo tiempo cortarán el cordón en longitudes más cortas.
Patent ES-265236-A1 (ES)
Title: Substituted 5-h-dibenz[b,f]azepines and their preparation
Filed: 1961-02-25
Abstract: The invention comprises 5H-dibenz[b,f]azepines of general formula <PICT:0914718/IV (b)/1> wherein X represents -CH2.CH2-, Y1 and Y2 each represent hydrogen, halogen, or an alkyl group of at most three carbon atoms, Z represents a straight or branched alkylene chain of at most six carbon atoms, and Am represents a hexamethylenimine radical which may be substituted with one or more alkyl radicals having at most 3 carbon atoms, their acidaddition and quaternary ammonium salts, and their preparation by (1) reaction of a compound of general formula <PICT:0914718/IV (b)/2> in the presence of a condensing agent with a reactive ester of an aminoalcohol of general formula HO-Z-Am (III) (2) thermal decarboxylation of a compound of general formula <PICT:0914718/IV (b)/3> (3) reaction of a reactive ester of a compound of general formula <PICT:0914718/IV (b)/4> with an amine of general formula Am-H (VI) or (4) by treating a compound of general formula <PICT:0914718/IV (b)/5> wherein Z1 and Am1 represent radicals that correspond to Z and Am respectively except that in at least one of them there is at least one carbonyl group instead of a methylene group bound to a nitrogen atom, with an alkali metal-earth hydride. The products are useful as pharmaceutical agents. Esters of general formula (IV) are obtained by reaction of phosgene with heterocycles of general formula (II), and reaction of the 5-chlorocarbonyliminodibenzyls so obtained with aminoalcohols of general formula (III). g -Hexamethyleniminopropanol is prepared by reduction of g -hexamethyleniminopropionic acid ethyl ester with lithium aluminium hydride. Hexamethylenimines of general formula (VI) are prepared by reduction of the corresponding e -caprolactams with lithium aluminium hydride. g -Hexamethylenimino-n-butyl chloride is obtained from 1,3-butylene glycol by reaction with acetyl chloride to form 3-chloro-n-butyl acetate, reaction of the latter with hexamethylenimine and conversion of the g -hexamethyleniminobutanol formed into the chloride, and g -hexamethylenimino-b -methylpropyl chloride is obtained by adding hydrogen bromide to b -methallyl chloride in the presence p of dibenzoyl peroxide and reacting the g -bromo-b -methylpropyl chloride formed with hexamethylenimine. 5-(a -Tert-aminocarbonylalkyl)iminodibenzyls are obtained by reaction of alkali metal derivatives of iminodibenzyls of general formula (II) with low a -bromoalkane carboxylic acid N,Nhexamethylene amides. 5-Hexamethyleniminoalkanoyliminodibenzyls are obtained by reacting alkali metal derivatives of compounds of general formula (II) with halogen alkane carboxylic acid halides and then reacting the halogen alkanoyl compounds obtained with a hexamethylenimine of general formula (VI). Other intermediates of general formula (VII) are obtained by reaction of esters of compounds of general formula (V) with alkali metal compounds of e -caprolactam or adipimide. Specifications 912,013 and 914,717 are referred to.
Patent ES-296835-A1 (ES)
Title: Steam generator unit control system
IPC: F22B35/14
Filed: 1964-02-25
Abstract: In a forced flow, once through boiler means are provided for use during the starting operation for reducing the pressure of the working fluid to a value such that it may be discharged into the condenser of the turbine supplied by the boiler, the means consisting of at least one elongated tube wherein the pressure reduction is effected by friction of the fluid in the course of its flow therethrough. In the apparatus shown, a feed pump drawing water from a condenser 10 forces the water through an evaporating section 2, the steam flowing through a shut-off valve 4 to and through a superheater 3 whence it passes to a turbine 8 through a stop valve 7, the turbine exhausting on to the condenser. A pipe branches from the tube system between the evaporator outlet and the valve 4 and leads to a header 14 through a valve 15. From the header 14 a number of small bore tubes 20 each with a control valve 4 and a pipe 22 with a reducing valve 23 lead to a header 17 connected by a pipe having a valve 18 to a separator 19. Steam and water flow from the separator to the condenser through liner 24, 26 respectively. A similar pressure reduction apparatus 28 is provided branching from the tube system between the superheater outlet and the valve 7. At the initial phase of the start-up operation the valve 4 is closed and water pumped through the evaporator flows through one or more of the tubes 20 entering the separator at reduced pressure. The boiler is fired and when the flow at the branch point 16 consists essentially of steam the pressure reducing valve 23 is opened and one or more shut-off valves 20 closed. As the steam reaches its desired operating pressure valve 4 is opened and steam flows through the superheater and is reduced in pressure in the apparatus 28 which at this stage may be used alone or with the first pressure reducing apparatus. Finally, the valve 7 is opened and the valves 15, 151 closed and steam at working pressure and temperature passes to the turbine.
Patent ES-298259-A1 (ES)
Title: Improvements in or relating to circuit arrangements including a discharge tube
Inventor: HILBERT PALMERS
IPC: H01P5/04
Filed: 1964-04-03
Abstract: In a discharge tube 5 circuit having a series choke 3 and capacitor 4, the volt ampere rating of the choke may be reduced to 0.9 to 1.15 of that of the tube by connecting an additional capacitor 8 having an impedance of 30 to 50 times the tube impedance either across the tube, or in series with the free ends of the electrodes 6, 7. The inductance of the choke 3 may be incorporated in a leakage transformer. The capacitor 8 has a value of 0.9 m.f.d. for a 40-watt tube.
Patent ES-307352-A1 (ES)
Title: Railway track without ballast
IPC: E01B3/40
Filed: 1964-12-11
Abstract: Railway track R is supported on blocks 3 seated in cavities 2 in a continuous surface 1 with the interposition of an elastomeric sheath C the bottom S of which has a closed cellular structure. The sheath surrounds the block 3 and is expanded to receive the block. The surface 1 is of concrete containing cement or asphalt and the blocks may be of concrete or wood joined by a rolled steel member 4. The rails R are secured to the blocks by elastic fasteners 11 and a pad 9 may be placed under the rail flange.
Patent ES-336677-A1 (ES)
Title: Preparation of cyclododecanone oxime
IPC: C01B/
Filed: 1967-02-10
Abstract: Cyclododecanone oxime is prepared by reacting cyclododecanone at 15-120 C. in the presence of a water-miscible solvent with an aqueous solution of a hydroxylamine mineral acid salt, the pH being kept in the range of from 4-6 by addition of a base and the said watermiscible solvent being an organic solvent with a boiling point in the range from 60 to 120 C., whereby two heterogeneous liquid organic and aqueous phases are formed and cyclododecanone oxime is obtained from the organic phase. Specified solvents are dioxane, propanol, isopropanol, tertiary butanol, acetonitrile and tetrahydrofuran. In a modification, a waterimmiscible extraction liquid in which the oxime dissolves is added before the two heterogeneous phases are separated.
Patent ES-339858-A1 (ES)
Title: Basically substituted oximes of 6,11-dihydro-dibenzo-[b,e]-oxepin- or thiepin-11-ones and their production
IPC: C07D313/12
Filed: 1967-04-27
Abstract: Novel compounds of the general formula <FORM:1123527/C2/1> (wherein X represents O or S, R1 represents H, halogen, alkyl or alkoxy, A represents a straight or branched C2- 6 alkylene chain, R2 and R3\t each represent H, alkyl or aralkyl or they represent two alkyl groups linked to form a ring, either directly or via an O or S atom or a N atom optionally carrying an alkyl or free or esterified hydroxyalkyl substituent) are prepared from the corresponding 6,11 - dihydrodibenzo - [b,e] - oxepin- or -thiepin-11-ones by (a) reacting them with (aminoalkoxy)-amines H2N-O-A-NR2R3 or acid addition salts thereof, or (b) converting them with hydroxylamine into their oximes, converting these into their alkali metal salts, and reacting the latter with reactive esters of hydroxyalkylamines HO-A-NR2R3. The products may be obtained in the form of, or converted into, pharmacologically acceptable salts with inorganic or organic acids. Pharmaceutical compositions, for oral or parenteral administration in the treatment of psychoses, comprise compounds of the general formula above, or their pharmacologically acceptable acid addition salts, in admixture with pharmaceutically acceptable carrier substances.
Patent ES-342557-A1 (ES)
Title: Improvements in or relating to a method of fastening elements on containers and apparatus therefor
IPC: B21D51/34
Filed: 1967-07-01
Abstract: A method of securing a valve &c. 14 on the inside or outside of a pressure vessel 11 for fuel gas or an aerosol &c. comprises forming a lip 15 on the element 14, forming an inward or outward depression 22 in the vessel in a single stamping or deep drawing operation, placing the lip 15 in the depression 22 and squashing the depression until its bottom surface is level with the vessel so that the side wall of the depression forms a crimping bead 23A, Fig. 7, around the lip 15. As shown, Fig. 3, the vessel and depression 22 are formed at the same time, by deep drawing dies 17, 18, 19. The internal die 25 for supporting the vessel during the crimping stage, has a recess 29 holding the element 14 and an annular recess 30 in which the bead 23A is formed. Sealing material may be used in the seam, and the element may be fixed to the exterior of the vessel, Fig. 8 (not shown).
Patent ES-356874-A1 (ES)
Title: A Composite Plough Share
IPC: A01B15/04
Filed: 1968-08-03
Abstract: A composite plough share comprises a tip portion 1 removably secured to a blade portion 2. The blade fits into a slot 3 and is secured by a bolt 7 which may also secure the blade to a sole 16 provided with a flange 17. The flange 11 may be secured to a counter sole 15 via means of a bolt 14.
Patent ES-363388-A1 (ES)
Title: Improvements in or relating to centrifugal pumps
IPC: F04D29/04
Filed: 1969-02-07
Abstract: A centrifugal pump comprises an impeller 4 mounted in a casing 1 so as to provide a suction chamber 18 on one side of the impeller and a pressure chamber 19 around the impeller, a casing cover 6 on the side remote from the suction chamber providing an enclosed space 17 between itself and the impeller, an annular gap seal 12 between the chambers 18, 19 provided by projections 10, 11, an annular gap seal 15 of larger diameter between the chamber 19 and the space 17 provided by projections 13, 14, and at least one throttle bore 16 through the impeller to provide a pressure drop, dependent on the dimensions of the throttle bore, between the space 17 and the chamber 18 to compensate for axial thrust on the impeller due to pressure in the chamber 19. A selected size of impeller 4 and casing 1 may be chosen from a range of sizes and attached to the cover 6, which remains unaltered.
Patent ES-371248-A1 (ES)
Title: Method and machine for forming containers
IPC: B31B17/46
Filed: 1969-09-05
Abstract: A carton having a base panel 46, Fig. 9, and two side panels 47, 48 hinged thereto has the two remaining sides formed of separate end panels secured to the panels 46, 47, 48 by glue flaps 46f, 47f, 48f. The panels are assembled by a plunger and die, the plunger moving horizontally. The blanks comprising the panels 46, 47, 48 are stacked vertically in a magazine above the plunger 78 and die 79, teeth 41 on a finger 39 feed each blank to rolls 44, 45 that pass the blank down to a position between the plunger and die. Flaps 46f, 47f, and 48f pass a glue applying roller as they move downwardly. The separate end panels 105, Fig. 9, are fed from two magazines, one on each side of the die and plunger. As each blank is fed downwardly it trips a plate 166 and withdraws a catch 175 so that the plunger is free to move into the die. As the plunger moves into the die, panels 46, 47, 48 are folded to U-shape and pickoff plates 107 on the trailing end of the plunger feeds an end panel 105 into each open end of the U-shaped panels 46, 47, 48. Members 110, 111 assisting initial folding of panels 47, 48 and deflectors 181 fold flaps 46f. Presser plates 119 are moved towards the folded blank and end panels and press the carton on to the plunger until the glue has set. A rock shaft 115 moves the plates 119. Movement of the plates 119, of the plunger into the die, and the feed of the blank comprising panels 46, 47, 48 are controlled by linkages from cams on a shaft 98 driven from an electric motor and by chain and sprocket gearing. An adjustable time delay is included in the electric control circuit. A quick setting hot glue is used to enable the machine to operate at high speed. If the output is to be reduced it is not feasible to run the machine more slowly since this would necessitate changing to a slower-setting glue. This problem is overcome by running the machine at its usual high speed but interrupting the cycle for a predetermined period of time. Springs 184 press on the top and bottom sides of a formed carton to bow those sides inwardly, the carton being ejected as the next blank is folded in the die and engages the inwardly bowed sides.
Patent ES-378844-A1 (ES)
Title: Device for adjusting the timing in fuel injection pumps
IPC: F02D1/18
Filed: 1970-04-21
Abstract: In a fuel injection pump, for an rpm-independent, arbitrary adjustment of the injection timing, there is provided an electromagnet which, on command, opens or closes a conduit to admit or cut off, respectively, a control pressure affecting an adjusting member and simultaneously, closes or opens a bypass channel communicating with said conduit upstream of said adjusting member.
Patent ES-414966-A1 (ES)
Title: Apparatus for cutting apertures in tubes
IPC: B26F1/00
Filed: 1973-05-19
Abstract: An improved pipe having an incised aperture wherein the length and/or width of the aperture increases from the interior surface of the pipe to the exterior thereof a process and apparatus for cutting an aperture in the surface of a pipe in which means for revolving a cutter about the pipe to be cut are provided and means for moving the cutting surface in an epitrochoid path as it passes through the exterior surface of said pipe.
Patent ES-420447-A1 (ES)
Title: Cyclopentylheptenoic acids and derivatives
IPC: C07C45/00
Filed: 1973-11-10
Abstract: The disclosure relates to novel intermediates, for use in the manufacture of known prostaglandins and prostaglandin-like compounds, for example aldehydes such as methyl 7-[2 beta -formyl-3 alpha -hydroxy-5 alpha -(4-phenylbenzoyloxy)cyclopent-1 alpha -yl]hetp-5-cis-enoate and enones such as methyl 15-oxo-9 alpha ,11 alpha -di(4-phenylbenzoyloxy)-5-cis,13-trans-prostadienoate, processes for their manufacture, and their conversion to prostaglandins or prostaglandin-like compounds.
Patent ES-420967-A1 (ES)
Title: Integrated circuit package
IPC: H05K7/14
Filed: 1973-11-29
Abstract: This package is suitable for both high density, relatively low input or output circuitry, such as memory circuits, and lower density, high input or output circuitry, such as logic circuits. The package has a plurality of substrates in a stack, with the high input or output circuits mounted on the bottom substrate in the stack and the lower input or output circuits mounted in the remaining substrates of the stack. The bottom substrate forms a portion of one wall of the closed container and has a plurality of interconnection pins in an array coextensive with and carried by its bottom surface. The remaining substrates of the stack have interconnection means brazed around their peripheries which are solder bonded to the next substrate in the stack. The bottom substrate is thus able to have a very large number of input/output pins, and the remaining substrates can be easily separated from the stack for rework purposes. In a preferred form, the package is fluid cooled and contains heat transfer baffles for removing heat from the package.