baber/WOPTO huggingface dataset:
Patent DE-69609957-D1 (DE)
Inventor: BECKETT PAUL
IPC: A61K31/185
Filed: 1996-04-18
Granted: 2000-09-28
Abstract: PCT No. PCT/GB96/00930 Sec. 371 Date Oct. 7, 1997 Sec. 102(e) Date Oct. 7, 1997 PCT Filed Apr. 18, 1996 PCT Pub. No. WO96/33161 PCT Pub. Date Oct. 24, 1996Compounds of formula (I), wherein X is a -CO2H or -CONHOH group;    <IMAGE>  (I)  R4 is a group -CHRxRy wherein Rx and Ry independently represent optionally substituted phenyl or monocyclic heteroaryl rings, which optionally may be linked covalently to each other by a bond or by a C1-C4 alkylene or C2-C4 alkenylene bridge; and R1, R2, R3 and R5 as defined in the specification are selective inhibitors of stromelysin-1 and matrilysin relative to human fibroblast collagenase and 72 KDa gelatinase.
Patent DE-69611690-D1 (DE)
Inventor: BEARDMORE GEOFFREY
IPC: G01R19/03
Filed: 1996-11-11
Granted: 2001-03-01
Abstract: PCT No. PCT/GB96/02773 Sec. 371 Date Oct. 14, 1998 Sec. 102(e) Date Oct. 14, 1998 PCT Filed Nov. 11, 1996 PCT Pub. No. WO97/17616 PCT Pub. Date May 15, 1997A current sensor assembly of planar form arranged for connection in series with an electrical circuit. The circuit includes a first and second conductor. The sensor assembly includes a first conductive member adapted to contact the second conductor in the circuit. A second conductive member is adapted to contact the second conductor in the circuit. A thin layer of conductive material is connected at one end to the first conductive member and at is other end to the second conductive member so that current flow in the circuit between the first and second conductors is via the thin layer. A support supports the thin layer along its entire length. At least a part of the support contacts the thin layer is electrically insulative. The thermal conductivity of the support is different at different points along the length of the layer so that heat disposition is different at the different points and hence the temperature rise caused by current flow through the layer is different. A plurality of temperature sensors are located to sense the temperature of the layer at the different points. The assembly provides an output representative of current from the outputs of the temperature sensors.
Patent DE-69613086-D1 (DE)
Inventor: FASSINA GIORGIO
IPC: A61K39/00
Filed: 1996-11-27
Granted: 2001-07-05
Abstract: An improved antigenic peptide where the amino acid sequence is modified by replacing one or more amino acids with glycine.
Patent DE-69623252-D1 (DE)
Inventor: YAMAZAKI AKIRA
IPC: A24D1/00
Filed: 1996-06-14
Granted: 2002-10-02
Abstract: The paper for rolling a smoking article of the present invention contains particle-form calcium carbonate (30 to 60 wt%), calcined clay (5 to 30 wt%) and pulp. Furthermore, an alkaline metal salt is contained as a chemical additive. In addition, kaolin is contained in the paper. The basis weight of the paper falls within the range of 20 to 70 g/m<2>. Optical characteristics of the paper and the burning characteristics and ash characteristics of a cigarette are improved and the side stream smoke is reduced.
Patent DE-69705062-D1 (DE)
Inventor: MEJIA ARMANDO
IPC: B65D35/22
Filed: 1997-10-30
Granted: 2001-07-05
Abstract: The web for a dual chamber tubular container can be maintained in an alignment across the container by providing one or more longitudinal modified areas on the web so that the web will yield and fold in the areas of the modified material. The modification will be a thinning or weakening of the web to produce yield points, such as fold points. This thinning or weakening can be produced mechanically or chemically. Mechanically, a pinch or other shaped roll can be used to thin or weaken an area. Thermally, heat can be applied. The result is a web that remains in an alignment across a tubular chamber rather than in close contact with the sidewall.
Patent DE-69708646-D1 (DE)
Inventor: SHIN MYOUNG KYUN
IPC: C21B11/00
Filed: 1997-12-19
Granted: 2002-01-10
Abstract: An apparatus for keeping an optimal penetration depth formed at the front end of an oxygen tuyere in the producing facilities of molten pig iron utilizing non-coking coal and a method for keeping the same. A sensor for measuring distance using a laser for continuously measuring the penetration depth, is provided. Comprised is a process computer for continuously receiving the measured penetration depth from the sensor and comparing the received penetration depth with a predetermined optimal penetration depth to obtain a difference between them, and for obtaining a changing amount of a pressure in a melter gasifier through a mutual relation between a predetermined changing amount of a pressure in the melter gasifier with that of the penetration depth using the difference between the actual penetration depth with the optimal penetration depth. A scrubber cone controlling device for receiving the changing amount of the pressure in the melter gasifier from the process computer for changing an opening degree of a scrubber cone to change the pressure in the melter gasifier, is included. The apparatus and the method can actively cope with the change of the volumetric flow rate of the oxygen and the change of the constituting material in a coal packed bed, and can actively control an applied pressure in the melter gasifier to control the blowing velocity of the oxygen. The penetration depth can be optimally kept.
Patent DE-69714639-D1 (DE)
Inventor: DE SADELEER JOS WILLY GHISLAIN
IPC: A23K10/28
Filed: 1997-04-22
Granted: 2002-09-19
Abstract: The present invention discloses a non-hygroscopic free-flowing product comprising a hydrophobic and a hydrophilic component. Preferred products comprise a hydrophobic protein together with hygroscopic components such as lactose, dextrose and choline. The present invention further discloses a method for making such a product. Furthermore animal feed compositions containing the non-hygroscopic free-flowing product are disclosed.
Patent DE-69718735-D1 (DE)
Inventor: TEN KATE RUDOLPH
IPC: H04H20/88
Filed: 1997-04-02
Granted: 2003-03-06
Abstract: An apparatus for encoding a plurality of n digital information signals is provided with at least a first, second and third input terminal (1,2,3) for receiving a first, a second and a third digital information signal (L,R,C). A matrixing unit (10) is provided for generating a first and a second digital composite signal (L0,R0) from the at least the first, second and third digital information signals. First and second data compression means (22.1,22.2) are provided for data compressing the first and second composite signal (L0,R0) so as to obtain first and second data reduced digital composite signals. A first selection unit (16) is provided for selecting at least one information signal from said plurality of n information signals so as to obtain at least a first auxiliary signal (AUX1). At least a third data compression means (22.3) is present for data compressing the at least first auxiliary signal so as to obtain a first data reduced auxiliary signal. A formatting unit (24) is present for combining the first and second data reduced composite signals and the at least first data reduced auxiliary signal into a transmission signal suitable for transmission via a transmission medium. The apparatus further comprises at least first, second and third masked threshold determining means (26.1,26.3,26.4) for determining first (mtL), second (mtC) and third (mtL0) masked thresholds respectively. A second selection unit (28.1) is provided for deriving one masked threshold from at least the first (mtL) and third (mtL0) masked threshold so as to obtain a first selected masked threshold (mt1). Preferably, said first selected masked threshold is the smallest of the said at least first (mtL) and third (mtL0) masked thresholds.
Patent DE-69728570-D1 (DE)
Inventor: MITRA SEKHAR
IPC: A61F7/02
Filed: 1997-12-05
Granted: 2004-05-13
Abstract: The present invention relates to a nasal dilator which comprises a means for dilating the nostrils and a thermal element, which can be worn on the nose of a human for an extended period of time, as well as a method of treatment for relief of nasal congestion/blockage, sinus discomfort and pain, and other cold and/or allergy symptoms associated therewith, by applying said nasal dilator to the nose of a human in need of such treatment.
Patent DE-69737126-D1 (DE)
Inventor: LOCARNINI ALISTER
IPC: C12N15/09
Filed: 1997-08-15
Granted: 2007-02-01
Abstract: The present invention relates generally to viral variants exhibiting reduced interactivity with immunological reagents. More particularly, the present invention is directed to hepatitis B variants exhibiting complete or partial resistance to nucleoside analogs and/or reduced interactivity with antibodies to viral surface components. The present invention further contemplates assays for detecting such viral variants which assays are useful in monitoring anti-viral therapeutic agents.
Patent DE-69806348-D1 (DE)
Inventor: ROESSLE HANS
IPC: B60R5/04
Filed: 1998-02-23
Granted: 2002-08-08
Abstract: Loading mat (1) for a floor of a luggage compartment of a vehicle, preferably of the type combi coupé, station wagon or minibus. The mat (1) has an upper side (2) and an underside (3). The mat (1) is provided with a stiff base layer (4) which gives the mat (1) such stiffness, at least in the longitudinal direction of the vehicle that allows the mat (1) to be pushed into respectively pulled out of the luggage compartment. The underside (3) which optionally constitutes the base layer (4) is glossy and has a low friction against the floor of the luggage compartment.
Patent DE-69806993-D1 (DE)
Inventor: HAMPL JUN
IPC: A24D1/02
Filed: 1998-03-11
Granted: 2002-09-12
Abstract: The present invention is generally directed to high opacity cigarette wrapping papers. The wrapping paper made according to the present invention contains a mixture of a white pigment and a black pigment. The white pigment, which can be, for instance, calcium carbonate, has a median particle size of from about 0.1 microns to about 0.5 microns, and particularly from about 0.2 microns to about 0.4 microns. It has been discovered that this particular particle size range, which is equal to one-half the wavelength of visible light, greatly increases the opacity, brightness and whiteness of the paper. Small amounts of a black pigment, such as carbon, are then added to further increase the opacity without significantly decreasing the whiteness or brightness of the paper relative to conventional cigarette paper.
Patent DE-69807878-D1 (DE)
Inventor: KORNELUK ROBERT
IPC: C12Q1/68
Filed: 1998-02-13
Granted: 2002-10-17
Abstract: Disclosed are diagnostic and prognostic methods and kits for the detection and treatment of proliferative diseases such as cancer (e.g. ovarian cancer, breast cancer, and lymphoma). Also disclosed are therapeutics for treating proliferative diseases (and methods for identifying such therapeutics) that utilize IAP and NAIP antisense nucleic acid molecules, antibodies which specifically bind IAP and NAIP polypeptides, and compounds that reduce the biological activities of IAP and NAIP polypeptides.
Patent DE-69813185-D1 (DE)
Inventor: PRIDMORE RAYMOND DAVID
IPC: C12N9/34
Filed: 1998-05-06
Granted: 2003-05-15
Abstract: A recombinant glucoamylase from Endomyces fibuliger comprising the amino acid sequence starting from one of the amino acids 1 - 50 up to amino acid 963 of SEQ ID NO:2, or functional derivatives thereof having at least 85% identity. A leader peptide of Endomyces fibuliger having the amino acid sequence starting from amino acid 1 to one of the amino acids 15 - 30 of SEQ ID NO:2. A DNA molecule which comprises a GLA2 gene encoding the enzyme according to the invention. A cell which expresses the proteins according to the invention by recombinant technology. A method for producing the enzyme according to the invention, comprising cultivating recombinant cells according of the invention in a suitable growth medium under conditions that the cells express the enzyme, and optionally isolating the enzyme in the form of a concentrate. The use of the recombinant protein or the cells of the invention to hydrolyse carbohydrate-containing materials, preferably materials containing rice carbohydrates.
Patent DE-69814588-D1 (DE)
Inventor: MILLER C
IPC: A63B21/005
Filed: 1998-01-08
Granted: 2003-06-18
Abstract: A passive exercise apparatus includes an interface member for coupling to a user's limb. An arm member is coupled to the interface member by a wrist joint. The wrist joint has rotational motion about three axes. A first link is coupled to the arm member by a sliding joint. The sliding joint allows translational motion of the arm member relative to the first link. A second link is rotatably coupled to the first link by a first rotary joint. A third link is rotatably coupled to the second link by a second rotary joint. A first brake is coupled to the first rotary joint for resisting movement of the first rotary joint. A second brake is coupled to the second rotary joint for resisting movement of the second rotary joint. A third brake is coupled to the arm member for resisting movement of the arm member. The user is capable of interfacing with the apparatus to exercise a six degree of freedom motion.
Patent DE-69816284-D1 (DE)
Inventor: ITOH KATSUMI
IPC: A61K31/4178
Filed: 1998-03-30
Granted: 2003-08-14
Abstract: A quaternized nitrogen-containing imidazol-1-yl or 1,2,4-triazol-1-yl compound wherein one of the nitrogen atoms constituting an azole ring is quaternized with a substituent capable of being eliminated in vivo and the substituent can be eliminated in vivo to be converted into an antifungal azole compound, has an improved solubility in water, can advantageously be applied to injection, has an improved internal absorption and can be expected to have a good effect for the treatment or prevention of disease.
Patent DE-69819545-D1 (DE)
Inventor: MARTTILA TOM
IPC: C25C7/02
Filed: 1998-09-24
Granted: 2003-12-11
Abstract: The invention relates to an electrode for electrolytic refining or electrowinning, said electrode (1, 21, 41) being provided with a hanger bar (3, 23, 43) attached to the edge of one plate-like mother plate, and the edges (4, 5, 6; 24, 30, 31; 44, 49, 50) of said electrode, apart from the edge to which the hanger bar is fastened, being protected with an edge strip (11, 12, 13; 29, 32, 33; 48, 51, 52) made of some insulating material, in which electrode at least part of the edge strips is at least partly placed in a groove (7, 25, 45) made in the electrode edge. According to the invention, at least in one electrode edge (4, 5, 6; 24, 30, 31; 44, 49, 50), there is formed a groove (7, 25, 45) for the electrode edge strip (11, 12, 13; 29, 32, 33; 48, 51, 52) made of some insulating material; the front end of said groove, located at the electrode edge (4, 5, 6; 24, 30 31; 44, 49, 50), being essentially equal in width with the rear end (10, 28, 53) of the groove placed inside the electrode. The invention also relates to a method for manufacturing the electrode (1, 21, 41).
Patent DE-69825790-D1 (DE)
Inventor: WEINSTEIN BERNARD
IPC: C12R1/07
Filed: 1998-11-25
Granted: 2004-09-23
Abstract: A biologically pure culture of a microorganism is provided designated SH2A and deposited under ATCC Accession No. 55926, or a mutant derived therefrom. Further provided is a biologically pure culture of a microorganism designated SH2B and deposited under ATCC Accession No. 202050, or a mutant derived therefrom. A method of degrading an organic material such as sludge is carried out by treating the organic material with an effective, degrading amount of either SH2A or a mutant derived therefrom, or SH2B or a mutant derived therefrom. The microorganism designated SH2A or a mutant derived therefrom, or SH2B or a mutant derived therefrom, is grown by culturing the microorganism at a temperature and in a medium effective to promote growth of the microorganism.
Patent DE-69827056-D1 (DE)
Inventor: LOOSBROEK PATRICK FRANCISCUS J
IPC: E06B9/56
Filed: 1998-02-19
Granted: 2004-11-25
Abstract: A screen (A) comprising a number of tension rollers (1, 2, 3), each having its free ends movably bearing-mounted in two lateral guides (4, 5; 13) and each being rotatable around the longitudinal center line (L) of the relevant tension roller (1, 2, 3), each tension roller (1, 2, 3) comprising a tension spring (6), the tension rollers (1, 2, 3) being interconnected by screen cloth parts (7, 7b, 7d), and the tension springs (6) in the tension rollers (1, 2, 3) being biased such that the screen (A) tends to assume a rolled-in condition and is extendible against the bias of the tension springs (6). <IMAGE>
Patent DE-69828946-D1 (DE)
Inventor: DANIEL M
IPC: A61F2/02
Filed: 1998-03-04
Granted: 2005-03-17
Abstract: The present invention relates to (with reference to Figures 16A, 16B) a collapsible intravascular distal protection device for an emboli capturing system. It comprises a guidewire (194) having a distal tip, an expandable member (200;208) attached to the guidewire (194), a mesh (202;210) attached to the expandable member (200;208), and a sheath (204) having a cavity sized to receive and collapse the expandable member (200;208) and attached mesh (202;210). The guidewire (194) is slidingly received with the sheath (204) and the distal tip of the guidewire (194) may extend beyond the end of the sheath (204). The expandable member (200;208) when expanded has a diameter greater than the diameter the sheath (204). Starting with the expandable member (200;208) received in the sheath (204), moving the sheath (204) away from the expandable member (200;208) using the actuator wire (196) allows the expandable member (200;208) and attached mesh (202;210) to expand from a collapsed position to a deployed position.
Patent DE-69831158-D1 (DE)
Inventor: KATTI V
IPC: A61P31/12
Filed: 1998-03-05
Granted: 2005-09-15
Abstract: A compound and method of making a compound for use as a diagnostic or therapeutic pharmaceutical comprises at least one functionalized hydroxyalkyl phosphine donor group and one or more sulfur or nitrogen donor and a metal combined with the ligand.
Patent DE-69836759-D1 (DE)
Inventor: PAESEN GUIDO CHRISTIAN
IPC: C07K14/435
Filed: 1998-11-12
Granted: 2007-02-08
Abstract: The present invention relates to tissue cement proteins produced by certain species of blood-feeding ectoparasites. These proteins and compositions comprising these proteins are particularly useful for the temporary or permanent bonding of animal tissues to each other or to other biomaterials. The present invention also relates to the use of tissue cement proteins in the production of vaccines that protect animals against the bite of blood-sucking ectoparasites and the transmission of viruses, bacteria and other pathogens by such ectoparasites.
Patent DE-69837450-D1 (DE)
Inventor: DAIFOTIS ANASTASIA G
IPC: A61P19/10
Filed: 1998-07-17
Granted: 2007-05-10
Abstract: Disclosed are methods for inhibiting bone resorption in mammals while minimizing the occurrence of or potential for adverse gastrointestinal effects. Also disclosed are pharmaceutical compositions and kits for carrying out the therapeutic methods disclosed herein. The compounds are bisphosphonates selected from the group consisting of alendronate, cimadronate, clodronate, tiludronate, etridronate, ibandronate, risedronate, piridronate, pamidronate, zolendronate, optionally in combination with a histamine H2 antagonist.
Patent DE-69841020-D1 (DE)
Inventor: BRAUD VERONIQUE M
IPC: G01N33/566
Filed: 1998-12-04
Granted: 2009-09-10
Abstract: The invention relates to a method of causing an interaction of CD94/NKG2+ cells, which method comprises contacting the cells with recombinant HLA-E under binding conditions. The HLA-E property of binding to CD94/NKG2 receptors on NK cells and a subset of CD8+ T cells is useful for targeting CD94/NKG2+ cells for a variety of purposes such as identification, isolation, killing or inactivation.
Patent DE-69911799-D1 (DE)
Inventor: SORENSEN BIRGER
IPC: D21D1/32
Filed: 1999-07-13
Granted: 2003-11-06
Abstract: A plant which serves to produce a nonwoven web of fibers out of a fibrous material, such a cellulose pulp. The plant comprises a hammer mill for defibrating the fibrous material and a forming head for forming a web of fibers on an endless forming wire, which, during operation, runs mainly horizontally, a first transport fan for transporting defibrated fiber to the forming head via a first air duct and a second transport fan to extract nits from the forming head via a second air duct. Furthermore, the plant comprises a separator, which is connected to the second air duct and arranged for separating the nits and the well-opened fiber, a third transport fan for returning the separated, well-opened fibers to the forming head, and a nits-opener for converting the separated nits into well-opened fiber. The separated nits are transported from the nits separator to the nits-opener by means of a fourth transport fan via a fourth air duct. The defibrated fibers are returned to the forming head by means of a fifth transport fan via a fifth air duct. The plant is easy to control and is capable of producing optimally high quality fiber products. In addition, the plant allows the defibrator to defibrate new fiber material at full capacity so that the remainder of the plant is able to produce at an optimum output level. The plant is furthermore very energy-saving.
Patent DE-69912436-D1 (DE)
Inventor: HOLTZAPPLE T
IPC: F04C18/344
Filed: 1999-07-27
Granted: 2003-12-04
Abstract: Novel vapor compression evaporative cooling systems which use water as a refrigerant are provided, as are methods for using same. Also provided are novel compressors, compressor components, and means for removing noncondensibles useful in such cooling systems.
Patent DE-69915320-D1 (DE)
Inventor: GORE GRAHAM
IPC: A01K27/00
Filed: 1999-09-14
Granted: 2004-04-08
Abstract: The present invention is directed to an immunoglobulin light chain binding protein which comprises the amino acid sequence of SEQ ID NO:1 modified by an amino acid substitution at one or more of positions 39, 53 and 57 and/or by an amino acid insertion between positions 59 and 60 such that the dissociation constant (Kd) of the protein with respect to human immunoglobulin kappa-chain is 400 nM or more at pH 8, or the amino acid sequence of a corresponding immunoglobulin light chain binding domain modified by an amino acid substitution at one or more of the positions equivalent to positions 39, 53 and 57 of SEQ ID NO:1 and/or by an amino acid insertion between positions equivalent to positions 59 and 60 of SEQ ID NO:1, such that the dissociation constant (Kd) of the protein with respect to human immunoglobulin kappa-chain is 400 nM or more at pH 8, or the amino acid sequence of a fragment of (a) or (b) which contains at least one said substitution and/or insertion, such that the dissociation constant (Kd) of the protein with respect to human immunoglobulin kappa-chain is 400 nM or more at pH 8.
Patent DE-69915711-D1 (DE)
Inventor: PALUDAN-MUELLER CARSTEN
IPC: H04R25/00
Filed: 1999-10-07
Granted: 2004-04-22
Abstract: In a hearing aid signal processor with AGC in at least three processing channels (a, B, C) for different frequency bands and with noise squelching capability to affect the gain control in a t least a lowest frequency band (A) and one intermediate frequency band (B) speech signals components in the intermediate frequency band of an input signal including background noise are intensified by estimation of the content of speech signal components in at least the highest frequency band (C) and modification of the gain adjustment cause by noise squelching in the intermediate frequency band (B) to reduce the noise spending. <heading lvl="1">RELATED APPLICATION </heading> The present application is a continuation-in-part of PCT/DK99/00531, filed Oct. 7, 1999, now abandoned.