baber/WOPTO huggingface dataset:
Patent NZ-597982-A (NZ)
Title: CHEMICAL COMPOUNDS for treating Hepatitis C virus
Inventor: CHEN PINGYUN
IPC: C07C403/00
Filed: 2010-08-26
Abstract: Patent No. 597982 Disclosed is a compound of formula I; wherein each R1 is independently H or C1-3 alkyl; each R2 is independently C1-3 alkyl; each X is independently CRR, O or S; n is 2 or 3; and each R is independently methyl, hydrogen or deuterium, such as methyl [(1S)-2-methyl-1-({ (2S)-2-[4-(4'-{ 2-[(8S)-7-((2S)-3-methyl-2-{ [(methyloxy)carbonyl]amino} butanoyl)-1,4-dioxa-7-azaspiro[4.4]non-8-yl]-1 H-imidazol- 4-yl} -4-biphenylyl)-1H-imidazol-2-yl]-1-pyrrolidinyl} carbonyl)propyl]carbamate.
Patent NZ-599618-A (NZ)
Title: Solvent-free process for obtaining phospholipids and neutral enriched krill oils
Inventor: CHIONG LAY MARIO M
IPC: A23L17/40
Filed: 2009-10-30
Abstract: Disclosed is a solvent-free process for producing krill oil, wherein the process comprises the following steps: a) cooking whole fresh krill and/or a fraction thereof at high temperature for protein denaturation, while avoiding emulsification in this step, neither in further processing steps; b) separating the cooked krill from step a) using a decanter with to obtain a partially defatted and de-watered solid and a decanter liquid; c) squeezing the partially de-fatted and de-watered solid from step b) to obtain a press liquid and a solid fraction; d) separating the press liquid from step c) to obtain krill oil enriched in phospholipids; e) separating the decanter liquid from step b) to obtain krill oil enriched in neutral lipids, and stickwater; f) optionally, drying the press liquid from step c) to obtain a dried complex of human grade krill which contains krill oil in combination with phospholipids, DHA, EPA, proteins and astaxanthin. Also disclosed is a solvent-free process for the production of krill oil, carried out on board at sea wherein the process comprises the following steps: a) cooking whole fresh krill and/or a fraction thereof at high temperature, while avoiding emulsification in this step, neither in further processing steps; b) separating the cooked krill from step a) to obtain a partially de-fatted and de-watered solid and a decanter liquid; c) squeezing the solid from step b) to obtain a press liquid and a solid fraction; d) separating the press liquid from step c) to obtain krill oil enriched in phospholipids; e) separating the decanter liquid from step b) to obtain krill oil enriched in neutral lipids, and stickwater; f) optionally, drying the press liquid [rom step c) to obtain a dried complex of human grade krill which contains krill oil in combination with phospholipids, DHA, EPA, proteins and astaxanthin.
Patent NZ-608179-A (NZ)
Title: Mono-energy and/or dual-energy engine with compressed air and/or additional energy, comprising an active chamber included in the cylinder
Inventor: NEGRE GUY
IPC: F24S90/00
Filed: 2011-10-03
Abstract: Disclosed is an engine with an active chamber (CA). The design of the engine allows for more controlled operation of the engine through a four phase thermodynamic cycle. The engine comprises at least one piston (2) slidably mounted in at least one cylinder (1) and driving a crankshaft (4) via a connecting rod (3) and crank pin (4). A high pressure storage reservoir (12) stores compressed air or any other compressed gas. The compressed air or gas is converted into a working volume (11) by a dynamic regulator device (13). The at least one cylinder (1) is divided into two distinct parts. A first part constitutes an active chamber (CA) and a second part constitutes an expansion chamber (CD). The cylinder (1) is closed at its upper part by a cylinder head (6). The cylinder head (6) comprises at least one intake duct (7) and port (9) and at least one exhaust duct (8) and port (10). When the piston (2) has reached a position at the upper part of cylinder (1), the residual volume left between the piston (2) and the cylinder head (6) is reduced to a minimum which allows operation without contact between the piston (2) and cylinder head (6). Compressed air or gas enters the cylinder (1) on top of the piston (2). Under continuous thrust of the compressed air or gas at a constant working pressure, the volume of the active chamber (CA) increases thus producing work and drives the piston (2) towards the lower part of the cylinder (1) into the expansion chamber (CD). The intake port (9) is closed off as soon as the maximum volume of the active chamber (CA) is reached. When the piston (2) reaches a position towards the lower part of the cylinder (1), the exhaust port (10) is opened and the exhaust phase takes place during the upstroke of the piston (2).
Patent NZ-609127-A (NZ)
Title: Novel fucosyltransferases and their applications
Inventor: PARKOT JULIA
IPC: C12N9/10
Filed: 2011-10-07
Abstract: Disclosed is an isolated polynucleotide encoding a polypeptide with alpha-1,3-fucosyltransferase activity and consisting of a sequence selected from the group consisting of: a) SEQ ID Nos. 1, 3, or 5; b) a nucleic acid sequence complementary to SEQ ID Nos. 1, 3, or 5; c) nucleic acid sequences which hybridise under stringent conditions to the nucleic acid sequences defined in a) and b) or their complementary strands; wherein the sequences are as disclosed in the specification.
Patent NZ-619087-A (NZ)
Title: Cartridge holder assembly for drug delivery devices
Inventor: KRAFT TORSTEN
IPC: A61M5/24
Filed: 2012-06-14
Abstract: Disclosed is a drug delivery device for administering a predefined dose of a medicament from a cartridge. That has a reliable mechanical inter-connection between the cartridge holder and the device body. The drug delivery device comprises a housing that comprises a body to accommodate a drive mechanism, a cartridge holder to accommodate a cartridge having a piston slidably disposed therein in an axial direction (z), and an interconnection (59) between cartridge holder and body. The interconnection has at least one displaceable or resiliently deformable latch element (68) to mate with a corresponding bearing (54), wherein the latch element (68) is displaceable or deformable in a direction (z, w) extending substantially parallel to a circumferential side wall (52, 65) of the body or cartridge holder. The cartridge holder and body comprise an insert portion and a corresponding receptacle portion for establishing an at least partially interleaved interconnection of cartridge holder and body. The receptacle portion comprises the at least one bearing extending in a lateral plane (x, y) with respect to a tubular shape of cartridge holder and/or body and extending radially inwardly from an inside facing side wall section of the receptacle. The bearing comprises at least one axial through opening to receive the latch element.
Patent NZ-623396-A (NZ)
Title: Methods for treating hcv
Inventor: RAY ADRIAN S
IPC: A61P31/14
Filed: 2012-09-14
Abstract: This disclosure relates to combinations of therapeutic molecules useful for treating hepatitis C virus infection. In one embodiment the combination comprises (S)-2-{ [(1R,4R,5R)-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-4-(R)-fluoro-3-hydroxy-4-methyl-tetrahydro-furan-2-yl-methoxy]-phenoxyphosphorylamino} -propionic acid isopropyl ester (compound 10), and 5-(3,3-dimethylbut-1-yn-1-yl)-3-[(cis-4-hydroxy-4-{ [(3S)-tetrahydrofuran-3-yloxy]methyl} cyclohexyl){ [(1R)-4-methylcyclohex-3-en-1-yl]carbonyl} amino]thiophene-2-carboxylic acid (compound 5) or (1-{ 3-[6-(9,9-difluoro-7-{ 2-[5-(2-methoxycarbonylamino-3-methylbutyryl)-5-aza-spiro[2.4]hept-6-yl]-3H-imidazol-4-yl} -9H-fluoren-2-yl)-1H-benzoimidazol-2-yl]-2-aza-bicyclo[2.2.1 ]heptane-2-carbonyl} -2-methyl-propyl)carbamic acid methyl ester (compound 6).The present disclosure relates to methods, uses, dosing regimens, and compositions.
Patent NZ-627247-A (NZ)
Title: Synthesis of calebin-a and its biologically active analogs
Inventor: NAGABHUSHANAM KALYANAM
IPC: C07C69/618
Filed: 2014-07-09
Abstract: Disclosed is a process for the synthesis of calebin-A (STR#3) and its biologically active analogs comprising mixing the iodomethyl ketone (STR#1) of the ketone part of the compound with an aqueous solution of the sodium or potassium salt of the acid part of the compound (STR#2), stirring the mixture at ambient temperature in the presence of a phase transfer catalyst for 24-72 hours, and subsequently separating the organic layer from the product of step B, washing with aqueous sodium hydrogen carbonate solution, drying over sodium sulfate, filtering off the solvent and crystallising from ethyl acetate or ethanol.
Patent NZ-629191-A (NZ)
Title: Tree wedge
Inventor: DANIEL JACKSON
IPC: A01G23/099
Filed: 2013-07-16
Abstract: A wedge to assist in felling trees but insertion into a tree cut is disclosed. The wedge (10 or 50) consists of two plates (11, 12) that pivot (13) at the end that inserts into the tree cut. A threaded shaft (16) passes through the opposite end of one of the plates so that it abuts the inner face of the other plate. When rotated the shaft pushes the plates apart, increasing the angle of the wedge and causing the tree to fall. The plates may lie substantially in the same plane where one fits within the perimeter of the other (10) or they may be of substantially the same size, one overlaying the other (50). The plate abutted by the shaft may include a recessed seat for the shaft end seat within. The wedge may also include a striking face to enable the wedge to be initially driven into the tree cut.
Patent NZ-711328-A (NZ)
Title: A process for preparation of (2s, 5r)-7-oxo-6-sulphooxy-2-[((3r)-pyrrolidine-3-carbonyl)-hydrazino carbonyl]-1,6-diaza-bicyclo[3.2.1]octane
Inventor: PATEL MAHESH VITHALBHAI
IPC: C07D471/08
Filed: 2013-10-12
Abstract: A process for preparation of (2S, 5R)-7-oxo-6-sulphooxy-2-[((3R)-pyrrolidine-3-carbonyl)-hydrazino carbonyl]-1,6-diaza-bicyclo[3.2.1]octane of Formula (I) is disclosed.
Patent NZ-726132-A (NZ)
Title: (s)-pirlindole or its pharmaceutically acceptable salts for use in medicine
Inventor: DAMIL JOÃO CARLOS
IPC: A61P25/04
Filed: 2014-05-09
Abstract: (S)-pirlindole or its pharmaceutically acceptable salts, as well as pharmaceutical compositions comprising the same for use in the therapeutic treatment and prevention of pain.
Patent NZ-729768-A (NZ)
Title: Tetrahydronaphthalene derivatives that inhibit mcl-1 protein
Inventor: BROWN SEAN P
IPC: A61K31/554
Filed: 2015-08-28
Abstract: Provided herein are myeloid cell leukemia 1 protein (Mcl-1) inhibitors, methods of their preparation, related pharmaceutical compositions, and methods of using the same. For example, provided herein are compounds of Formula I, (I) and pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the compounds. The compounds and compositions provided herein may be used, for example, in the treatment of diseases or conditions, such as cancer.
Patent NZ-737505-A (NZ)
Title: Child resistant slider having insertable torpedo and methods
Inventor: CHAPEK CARLOS
IPC: B65D50/04
Filed: 2014-04-04
Abstract: A slider (1) for a zipper closure (36) for a child resistant zipper pouch (B) is provided to increase the difficulty for children to open the pouch (B). The slider (1) includes a male track (18) and a female track (19) with complementary profiles (14, 15) for interlocking and unlocking. The slider (1) includes a tab (2). The slider (1) includes a torpedo (3) extending from a bottom surface (42) of the tab (2) and being selectively moveable into a position to be between the male track (18) and female track (19) and result in separation of the interlocking profiles (14, 15) as the slider (1) is moved in an opening direction along the zipper closure (36).
Patent NZ-741447-A (NZ)
Title: Compacted hemostatic cellulosic aggregates
Inventor: WANG YI-LAN
IPC: A61L15/24
Filed: 2016-10-28
Abstract: The present invention is directed to a hemostatic material comprising a compacted, hemostatic aggregates of cellulosic fibers. In some aspects, the hemostatic material further includes additives, such as carboxymethyl cellulose (CMC) or other polysaccharides, calcium salts, anti-infective agents, hemostasis promoting agents, gelatin, collagen, or combinations thereof. In another aspect, the present invention is directed to a method of making the hemostatic materials described above by compacting a cellulosic-based material into hemostatic aggregates. In another aspect, the present invention is directed to a method of treating a wound by applying hemostatic materials described above onto and/or into the wound of a patient.
Patent NZ-761319-A (NZ)
Title: Enabling and disabling location sharing based on environmental signals
Inventor: RUSU ANDI F
IPC: G01S1/00
Filed: 2018-06-22
Abstract: Environmental signals are used to determine when to prompt a user to enable location sharing on their computer devices. These environmental signals may include the current location of the user being an unusual location for the user or a location that is tagged as a known social location such as a concert venue, stadium, or park. The environmental signals may also include one or more friends of the user being near the user. If the user chooses to enable location sharing in response to the prompt, the location of the user may be shared with some or all of their friends, or just the friends that have been determined to be near the user. After some amount of time has passed, or the environmental signals have changed, the location sharing may be automatically disabled for the user.
Patent NZ-784956-A (NZ)
Title: Novel method for preparing long-acting drug conjugate through preparation of intermediate
Inventor: SHIN CHEONGBYEOL
IPC: C08G65/325
Filed: 2019-07-18
Abstract: The present invention relates to a novel intermediate for preparing a long-acting drug conjugate, a composition including the same, and a method for preparing the long-acting drug conjugate using the same. In particular, a compound of the invention is a compound having a structure of Formula 1 below or a stereoisomer, a solvate, or a pharmaceutically acceptable salt thereof: [Formula 1] X–L1–O(CH2CH2O)n–L2–R wherein in Formula 1 above, X is an immunoglobulin Fc region and comprises, at the N-terminus, a hinge sequence that comprises an amino acid sequence of SEQ ID NO: 9 (Pro-Ser-Cys-Pro); L1 is a straight or branched-chain C1–C6 alkylene; L2 is –a1–CONH-, –a1–NHCO–, –a1–NHCO–a2–, –COO–, –b1–COO–, –COO–b2–, or –b1–COO–b2–, in which a1, a2, b1, and b2 are each independently a straight or branched-chain C1–C6 alkylene; n is from 10 to 2400; and R is any one selected from the group consisting of 2,5-dioxopyrrolidinyl, 2,5-dioxopyrrolyl, aldehyde, maleimide, C6–C20 aryl disulfide, C5–C20 heteroaryl disulfide, vinyl sulfone, thiol, halogenated acetamide, succinimide, p-nitrophenyl carbonate, and thioester.
Patent PT-102759-A (PT)
Title: Machine for crushing olives and similar has two crushing chambers one inside other, outer chamber being cylindrical with side surface comprising grid with holes
Inventor: PIERALISI GENNARO
IPC: B07B1/14
Filed: 2002-04-11
Abstract: The machine for crushing olives (2) and similar has two chambers, one inside the other. The outer chamber (100) is cylindrical with a side surface comprising a grid (101) with holes (101a). Inside the outer chamber are devices (200) which rotate when driven by associated components to crush the olives. An additional crushing chamber (1100) is arranged inside the outer.
Patent RU-94004853-A (RU)
Inventor: JURKOV D A
IPC: G06F15/16
Filed: 1994-02-14
Abstract: FIELD: computer engineering. SUBSTANCE: additional commutator are introduced to accomplish the goal of invention. Device provides possibility to transmit low amount of information between several computers using standard interfaces and standard software. EFFECT: increased functional capabilities.
Patent RU-94007612-A (RU)
Inventor: LIPIN V D
IPC: A01C7/04
Filed: 1994-03-01
Abstract: FIELD: agricultural engineering; precision seeding devices. SUBSTANCE: seeding apparatus has additional plates installed between parts of rings forming semicells when seeding small seeds. Plates are installed for displacement relative to parts of rings around disk axis with subsequent locking. Additional plates are provided with cutout for seed ejector blade. EFFECT: possibility of planting small-size seeds.
Patent RU-94007798-A (RU)
Inventor: EGOROV A A
IPC: G05F1/70
Filed: 1994-03-03
Abstract: FIELD: electrical engineering; improving electricity parameters of AC supply mains loaded with induction motors. SUBSTANCE: method involves correction of induction motor reactive power by maintaining its power factor close to unity within wide range of motor loads at the same time reducing capacitance of passive condensers. Special correction of running winding parameters and use of autotransformer circuit arrangement for connecting correcting condensers to auxiliary winding allow for obtaining external characteristics at which motor power factor at load varying from partial to rated value is practically unity. EFFECT: provision for full correction of reactive currents within wide range of motor loads without controlling correction devices; reduced quantity of passive condensers; ability to implement this method in practice.
Patent RU-94009464-A (RU)
Inventor: CHEREBAEV G V
IPC: B60N2/10
Filed: 1994-03-18
Abstract: FIELD: transport engineering; cars of improved comfort; folding seats. SUBSTANCE: position of rear guides relative to members of bar of cushion 2 and base of seat 1 is changed. For this purpose rear guides can be arranged horizontally in seat 1 of car which has members of bar of cushion 2 of seat 1 and base between which front and rear guides and locks with release drive are hinge-mounted. EFFECT: increased range of displacement of seat members, simplified design of seat and increased reliability of fixing and functioning. 1 dwg
Patent RU-94020061-A (RU)
Inventor: KUZNETSOV S M
IPC: E21B43/20
Filed: 1994-05-30
Abstract: FIELD: oil production. SUBSTANCE: method for developing oil deposit includes injection of working agent through injection wells in cyclic mode of operation, and oil extraction through producing wells. Three groups of well are selected from all majority of the wells. The first group includes producing wells with complete flooding, in essence, of the product to be produced. The second group includes producing wells with flooding level of the product to produced close to limiting one according to economical quantities, and liquid discharge exceeding 50 cubic meters daily. The third group includes producing wells with flooding exceeding 50 % and liquid discharge below 10 cubic meters daily. The first group of the producing wells is operated until complete flooding of the product to produced. The second group of the wells is separated into zonal subgroups. Producing wells of adjacent zonal subgroups are operated in antiphase during 4 - 6 months. Periodical outage for the time of decreased water/oil relationship changes with operation until water/oil relationship is increased up to limiting flooding. Then producing wells of all zonal subgroup are stopped for 6 - 8 months. In so doing zonal subgroups of producing wells are formed under condition of equivalent liquid extraction in each zonal subgroup, and availability of producing wells of a zonal subgroup within effective area of injection wells provided with the same source of working agent. The third group of producing wells is operated in cyclic mode for 4 - 6 months. The wells outage during time less than 24 hours changes with operation less than 24 hours. Then the wells are stopped for 6 - 8 months. With wells of the second group stopped, concurrent decrease to 25 % mean value in amount of injected agent is carried out thought groups of injection wells effecting on a zonal subgroup. When operating producing wells amount of injected agent is increased to 25 % mean value. EFFECT: high productivity.
Patent RU-94027346-A (RU)
Inventor: PROVOLOVICH O V
IPC: B03C3/12
Filed: 1994-07-19
Abstract: FIELD: cleaning of air in two-zone electric filters of solid and liquid particles in ventilation systems; various branches of industry. SUBSTANCE: corona-forming electrode is located in ionization zone in such position that ratio of distance from its corona-forming edge to zone of deposition to length of deposition zone is within 0.7 to 0.8. EFFECT: enhanced efficiency of cleaning and reduced overall dimensions.
Patent RU-94040870-A (RU)
Inventor: ZHAN-FRANSUA SHANEZ
IPC: A61L27/00
Filed: 1994-08-05
Abstract: FIELD: medical engineering. SUBSTANCE: device is introduced into the vaginal cavity (VA) and kept there under the urinary bladder (VE) so that it gives support to the urinary bladder and the ureter (UR) through the anterior vaginal wall to prevent the urinary bladder neck from its going down. The device has removable casing 1 having no sharp corners and manufactured from an unsticking material non-active from both chemical and biological point of view to be unable to make problems related to allergy. Removable casing 1, which presence does not hinder the urination, is easily installable by the user in the vaginal cavity (VA) and is removable when needed. EFFECT: enhanced reliability of functioning.
Patent RU-94042012-A (RU)
Inventor: ANDRONOV V A
IPC: E02F9/02
Filed: 1994-11-23
Abstract: FIELD: building machines production. SUBSTANCE: guide wheel is made of two parts (discs) of a simple shape, that allows one to increase significantly homogeneity of ingot structures and reliability of the guide wheel. The discs are interconnected inside a hub through pressing, and welding around outer surface of the rim. Guide ledges are made on each disc and sifted from joint surface towards the races. The discs the guide wheel are made of armored cast steel of middle hardness. EFFECT: reliability of the guide discs. 2 dwg
Patent RU-94042197-A (RU)
Inventor: GRACHEV V A
IPC: C21C1/00
Filed: 1994-11-22
Abstract: FIELD: ferrous metallurgy; copper and tin-alloyed cast iron. SUBSTANCE: as an alloy, silicon brass cuttings are used in amount 6-11% based on weight of processed cast iron. Invention permits obtaining pearlite-type cast iron. EFFECT: reduced cost and increased reactive purity of alloy. 1 cl
Patent RU-94042644-A (RU)
Inventor: NOSOV V R
IPC: B60R25/04
Filed: 1994-11-29
Abstract: FIELD: transport; prevention of stealing. SUBSTANCE: method comes to the following: with engine shut down, exhaust pipe channel is overlapped by shutter and before authorized starting the engine, exhaust gas channel is opened. EFFECT: enhanced efficiency of protection against stealing.
Patent RU-95102326-A (RU)
Inventor: KHIUNG DONG CHANG
IPC: H01S3/0933
Filed: 1995-02-20
Abstract: FIELD: radio engineering. SUBSTANCE: device has control unit which controls input excitation signal, unit which matches electric power and pulse discharge for receiving said exciting signal, which is controlled by said control unit, which as result outputs electric power. In addition device has power accumulation unit which receives said electric power from electric power matching unit and which also accumulates received electric power. In addition device has source of starting radiation and excitation unit for generation low-power optical laser beam while electric power is accumulated in accumulation unit. In addition device has unit of optical-controlled semiconductor switch. Said unit converts electric power which is accumulated as capacitor charge into pulse surge. In addition device has powerful laser matrix which converts said current surge into heavy optical beam. Said unit of optical-controlled semiconductor switch is designed as three-pole switch which has three electrodes. EFFECT: increased output peak power, decreased pulse duration and increased repetition rate.