baber/WOPTO huggingface dataset:
Patent WO-2022099137-A1 (WO)
Title: Devices, methods, and apparatuses for mitigating insufflation gas leakage from a trocar
Inventor: GILKEY JAMES
IPC: A61B17/34
Filed: 2021-11-08
Abstract: Disclosed herein are sealing devices configured for improving sealing functionality with an engaged extension member of an apparatus. More specifically, disclosed herein are trocar sealing devices configured for improving insufflation gas containment in relation to trocars (and/or other related type of devices) that are used for enabling a surgical instrument such, for example, a laparoscope, to gain access to an abdominal cavity (or other body cavity). By providing for such improved insufflation gas containment, sealing devices as disclosed herein are particularly advantageous, desirable and useful in view of long-standing reasons for limiting insufflation gas leakage and in view of newly recognized reasons stemming from outbreak of COVID-19 disease for limiting insufflation gas leakage.
Patent WO-2022103987-A1 (WO)
Title: Photocatalytic generation of singlet oxygen for air purification
Inventor: GRUBBS ROBERT H
IPC: C01G39/04
Filed: 2021-11-11
Abstract: Aspects disclosed herein include a system for generating singlet oxygen in a gas, the system comprising: a substrate; and hexanuclear clusters operably immobilized on at least a portion of the substrate; wherein each hexanuclear cluster comprises a photosensitive octahedral core complex characterized by formula FX1a: M 6 X 8  (FX1a); wherein each M is independently Mo, W, or Re; wherein each X is independently a halide anion ligand; wherein the clusters are exposed to the gas and the gas comprises O 2  gas; wherein the clusters are exposed to a light; and wherein each hexanuclear cluster is a photosensitizer configured to generate the gaseous singlet oxygen when irradiated by the light in the presence of the O 2  gas.
Patent WO-2022109135-A1 (WO)
Title: Systèmes chirurgicaux et procédés pour déterminer la profondeur de pénétration d'outils de coupe
Inventor: SHARMA RAHUL
IPC: A61B17/16
Filed: 2021-11-18
Abstract: L'invention concerne un système chirurgical permettant de déterminer la profondeur de pénétration d'un alésage dans un os à travers une couche corticale proximale d'os et une couche corticale distale d'os. Le système chirurgical comprend un instrument destiné à être accouplé à un outil de coupe. Un capteur est couplé à l'instrument pour générer une ou plusieurs mesures de profondeur de l'outil de coupe lorsque l'outil de coupe effectue une coupe à travers l'os. La profondeur de pénétration est déterminée sur la base de mesures de profondeur effectuées après que l'outil de coupe a traversé la couche corticale proximale d'os. La profondeur de pénétration est facultativement basée sur un type d'os coupé, une dureté osseuse et une sélection d'outil de coupe.
Patent WO-2022132408-A1 (WO)
Title: Systems and methods for visual anomaly detection in a multi-display system
Inventor: GUPTE POOJA ASHOKBHAI
IPC: G06F21/50
Filed: 2021-11-23
Abstract: Embodiments described herein are directed to visual anomaly detection for content displayed via multi-display systems. For instance, computing devices may provide content for display by a respective display devices of a multi-display system. Each computing device provides images of the content, along with an identifier identifying the computing device as the source of the image, to a cloud-based storage system. A cloud-based visual anomaly detection system retrieves and analyzes the images from the storage system and determines whether any visual anomalies are present therein. The analysis is performed on a per-computing device basis. For instance, the system may apply a machine-learning based detection model to an image that is specific to the computing device that generated the image based on the identifier associated with the image. Upon detecting an anomaly, an automated action is performed to remediate the cause of the anomaly.
Patent WO-2022146995-A1 (WO)
Title: Système chirurgical pour couper au moyen d'une aide naviguée
Inventor: JARAMAZ BRANISLAV
IPC: A61B34/20
Filed: 2021-12-28
Abstract: Sont décrits ici des ensembles bras robotiques qui sont conçus pour faciliter des coupes planes dans une intervention chirurgicale orthopédique. Bien que les ensembles bras robotiques aient moins de trois articulations motorisées, ils possèdent toutefois la fonctionnalité d'ensembles bras robotiques classiques qui ont des nombres plus importants d'articulations motorisées. Les ensembles bras robotiques comprennent en outre une à quatre articulations non motorisées. Les articulations non motorisées peuvent comprendre des mécanismes de freinage ou de verrouillage qui sont configurés pour ralentir ou verrouiller sélectivement le mouvement des articulations et les sections de bras associées de l'ensemble bras robotique.
Patent WO-2022147107-A1 (WO)
Title: Modular continuous flow bioreactor
Inventor: ALZATE OSCAR
IPC: C12M1/36
Filed: 2021-12-29
Abstract: Described herein is a modular continuous flow bioreactor for various cells. In one embodiment, the modular cell culture bioreactor apparatus may comprise a plurality of cell chambers disposed between an upper flow chamber and a lower flow chamber; a plurality of lower conduits fluidly connecting the lower flow chamber with one or more lower reservoirs and a plurality of upper conduits fluidly connecting the upper flow chamber with one or more upper reservoirs; one or more pumps fluidly connected through the plurality of conduits with the one or more reservoirs and with the upper and lower flow chambers; wherein each individual cell chamber comprises a lower permeable membrane in fluid communication with the lower flow chamber, a three-dimensional distribution of cells, and an upper permeable membrane in fluid communication with the upper flow chamber.
Patent WO-2023027760-A1 (WO)
Title: Exploration de processus contrainte par l'utilisateur
Inventor: BRONS DENNIS
IPC: G06F11/34
Filed: 2021-11-01
Abstract: L'invention concerne des systèmes et des procédés destinés à générer un arbre de processus d'un processus. Un journal d'événements de l'exécution d'un processus est reçu. Des contraintes d'utilisateur sur une ou plusieurs activités du processus sont reçues de la part d'un utilisateur. Un arbre de processus est généré à partir du journal d'événements sur la base des contraintes d'utilisateur. L'arbre de processus est délivré.
Patent WO-2023014397-A1 (WO)
Inventor: SCHUETZLE ROBERT
IPC: C01B3/30
Filed: 2022-07-21
Abstract: The present invention is generally directed to the efficient production of low-carbon methanol, ethanol or mixtures of methanol and ethanol from captured CO 2  and renewable H 2  at a generation site. The H 2  is generated from water using an electrolyzer powered by renewable electricity, or from any other means of low-carbon H 2  production. An improved catalyst and process is described that efficiently converts H 2  and CO 2  mixture to syngas in a one-step process, and alcohols, such as methanol and ethanol, are produced from the syngas in a second step. The liquid methanol and ethanol, which are excellent H 2  carriers, are transported to a production site, where another improved catalyst and process efficiently converts them to syngas. The syngas can then be used at the production site for the synthesis of low carbon fuels and chemicals, or to produce purified low carbon H 2 . The low carbon H 2  can be used at the production site for the synthesis of low-carbon chemical products or compressed for transportation use.
Patent WO-2022150581-A1 (WO)
Title: Fuel injector devices, systems, and methods
Inventor: EDWARDS ROMAINE O
IPC: F02M61/16
Filed: 2022-01-07
Abstract: Disclosed herein are devices, systems and methods relating to fuel injectors. A fuel injector nozzle can include an injector cavity, a sac, and one or more spray holes. The sac can extend from an injector cavity distal end. In examples, a vertical cross section of the sac can be pear shaped. The sac can include a sac volume defined by a diverged portion that extends from the injector cavity distal end and a converged portion that extends from the diverged portion. The one or more spray holes can extend from an inlet opening at the sac volume to an outlet opening. The inlet opening can be positioned within the sac to reduce cavitation caused by vapor collapse at the sac.
Patent WO-2022155141-A1 (WO)
Title: Réacteur de pyrolyse avec échange de chaleur intégré
Inventor: SHANER SAMUEL
IPC: B01J35/12
Filed: 2022-01-11
Abstract: Un échangeur de chaleur à contact direct pour un réacteur à milieu fondu peut comprendre une pluralité de plateaux ou étages disposés dans une cuve, un trajet d'écoulement de milieu fondu conçu pour faire passer un milieu fondu à travers la pluralité de plateaux ou d'étages, et un trajet de gaz disposé à travers la pluralité de plateaux ou d'étages. Le trajet de gaz est conçu pour entrer directement en contact avec un fluide en phase gazeuse avec le milieu fondu sur la pluralité de plateaux ou d'étages.
Patent WO-2022159829-A1 (WO)
Title: Compositions comprising pedf-derived short peptides (pdsp) and uses thereof
Inventor: LEE FRANK WEN-CHI
IPC: A61K47/00
Filed: 2022-01-24
Abstract: An aqueous formulation includes a PEDF-derived short peptide (PDSP) having the sequence of one of SEQ ID NO: 1, 2, 3, 5, 6, 8, or 9; boric acid at a concentration of 0.01 mM – 923 mM; and a non-ionic tonicity agent. The pH value is around 5.5–8.4. The non-ionic tonicity agent is glycerin, sucrose, mannitol, or sorbitol. A concentration of the PDSP is 0.01% - 1% w/v.
Patent WO-2022170038-A1 (WO)
Inventor: GOLDMAN MITCHELL
IPC: A61K48/00
Filed: 2022-02-04
Abstract: La présente divulgation concerne l'administration de virus adéno-associé recombinant (rAAV) d'un polynucléotide de céroïde-lipofuscinose neuronale (CLN3). La divulgation fournit des rAAV et des méthodes d'utilisation du rAAV pour la thérapie génique par CLN3 de la céroïde-lipofuscinose neuronale ou de la maladie de Batten liée à CLN3.
Patent WO-2022186952-A1 (WO)
Inventor: TOPCHY ALEXANDER
IPC: G10L19/025
Filed: 2022-02-07
Abstract: Procédés, appareil, systèmes et articles de fabrication permettant de réaliser une empreinte digitale d'un signal audio. Un appareil donné à titre d'exemple divulgué ici comprend un dispositif de segmentation audio pour diviser un signal audio en une pluralité de segments audio, un dispositif de normalisation de cases pour normaliser le second segment audio afin de créer ainsi un premier segment audio normalisé, un générateur de sous-empreinte digitale pour générer une première sous-empreinte digitale à partir du premier segment audio normalisé, la première sous-empreinte digitale comprenant une première partie correspondant à un emplacement d'un extrémum d'énergie dans le second segment audio normalisé, un évaluateur de force de partie pour déterminer une probabilité de changement de la première partie, et un dispositif de remplacement de partie pour remplacer, en réponse à la détermination que la probabilité ne satisfait pas à un seuil, la première partie par une seconde partie pour ainsi générer une seconde sous-empreinte digitale.
Patent WO-2022182758-A1 (WO)
Title: Ligne de transmission à couplage résonant
Inventor: WESTWOOD ANDREW
IPC: G01R31/28
Filed: 2022-02-23
Abstract: L'invention concerne un exemple de carte de circuit imprimé (PCB) comprenant un substrat ayant des couches d'un matériau diélectrique, les couches de matériau diélectrique comprenant une première couche et une seconde couche ; une trace conductrice qui se trouve entre la première couche et la seconde couche et qui est parallèle à la première couche et à la seconde couche le long d'au moins une partie d'une longueur de la trace conductrice ; et un trou d'interconnexion conducteur qui s'étend au moins en partie à travers les couches de matériau diélectrique et qui se connecte électriquement à la trace conductrice, le trou d'interconnexion conducteur étant également configuré pour se connecter électriquement à une entrée de signal pour recevoir ou émettre un signal qui a une portée de fréquence centrale.
Patent WO-2022182792-A1 (WO)
Inventor: RYCHAK JOSHUA
IPC: A61K38/00
Filed: 2022-02-23
Abstract: La présente invention concerne des compositions et des procédés pour la modification génétique de cellules, comprenant, mais sans s'y limiter, des hépatocytes. Les compositions et les procédés peuvent comprendre des nanoparticules lipidiques, les nanoparticules lipidiques comprenant au moins un lipide cationique ionisable bioréductible, au moins un lipide structural, au moins un phospholipide et au moins un lipide pegylé.
Patent WO-2022187135-A1 (WO)
Inventor: AI-MAHSHI WALEED
IPC: F16D65/18
Filed: 2022-02-28
Abstract: A brake system (10) comprising: a brake caliper (12) supporting a brake pad (14), and having a first brake piston (24) and a second brake piston (28) that are configured to move the brake pad; a first rotary to linear stage mechanism (32) connected to the first brake piston, and a second rotary to linear stage mechanism (34) connected to the second brake piston; a motor (42) configured to generate torque; a torque distributing assembly (40) configured to receive torque from the motor and then distribute the torque from the motor to the first rotary to linear stage mechanism to move the first brake piston and/or to the second rotary to linear stage mechanism to move the second brake piston; wherein the torque distributing assembly comprises: i) a first driving gear (44) connected to the first rotary to linear stage mechanism; ii) a second driving gear (46) connected to the second rotary to linear stage mechanism; iii) a first set of planet gears (72) supported on respective first axles (74); iv) a second set of planet gears (98) supported on respective second axles; and v) a first carrier plate (88) having a plurality of support features each configured to support a respective one of the first axles and a respective one of the second axles.
Patent WO-2022197487-A1 (WO)
Inventor: MYLARI Banavara
IPC: A61K31/5025
Filed: 2022-03-08
Abstract: The subject invention provides pharmaceutical compositions comprising combinations of probenecid or a pharmaceutically acceptable salt thereof, and one or more carboxylic acid aldose reductase inhibitors (ARIs) or pharmaceutically acceptable salts thereof. The subject invention also provides methods of using such combinations to treat mammals, including humans, suffering from diabetic complications such as, diabetic neuropathy, diabetic nephropathy, diabetic retinopathy, diabetic cataracts, diabetic cardiovascular complications, including cardiomyopathy, myocardial infarction, heart failure and atherosclerosis and non-diabetic cardiovascular complications, including myocardial infarction, coronary artery disease, atherosclerotic cardiovascular diseases and heart failure.
Patent WO-2022197845-A1 (WO)
Inventor: APPLEYARD DAVID
IPC: G01N15/14
Filed: 2022-03-16
Abstract: L'invention divulgue une approche pour différencier différents types de particules dans des échantillons s'écoulant à travers des puces microfluidiques. Un échantillon peut présenter une proportion initiale d'un premier type de cellule à un second type de cellule. Une source de lumière d'éclairage peut émettre une lumière cohérente au niveau de l'échantillon, et la lumière sortant de la puce dans une première direction peut être détectée à l'aide d'un premier détecteur de lumière, et la lumière sortant de la puce dans une seconde direction (par exemple, orthogonale à la première direction) peut être détectée à l'aide d'un second détecteur de lumière. La lumière détectée peut être fluorescente. Une caractéristique d'orientation d'une pluralité de cellules dans l'échantillon peut être déterminée sur la base de la lumière détectée par les détecteurs. Sur la base des caractéristiques d'orientation et de la lumière détectée, une opération de polarisation peut être effectuée pour chaque cellule dans l'échantillon pour obtenir une proportion modifiée de types de cellules dans l'échantillon.
Patent WO-2022212165-A1 (WO)
Inventor: WOODARD STEVEN
IPC: B01D15/00
Filed: 2022-03-24
Abstract: A system for separating competing anions from per- and polyfluoroalkyl substances (PFAS) in a flow of water contaminated with PFAS and elevated levels of competing anions that includes a separation subsystem which receives the flow of water contaminated with PFAS and elevated levels of competing anions and separates competing anions from the PFAS and concentrates the PFAS to produce a treated flow of water having separated competing anions therein and a flow of water having a majority of PFAS therein. At least one anion exchange vessel having an anion exchange resin therein receives the flow of water having a majority of PFAS therein and removes PFAS from the water to produce a flow of treated water having a majority of the PFAS removed. The separation of competing anions by the separation subsystem increases the treatment capacity of the anion exchange resin to remove PFAS from the contaminated water.
Patent WO-2023282954-A1 (WO)
Inventor: FOWLER MARK
IPC: G02B6/46
Filed: 2022-04-13
Abstract: A cable-shaving tool for midspan shaving of a cable jacket includes a housing bottom having a first hinge member along an upper edge, a cavity, and at least one cable groove extending through a length of the housing bottom. The cable-shaving tool includes a second housing shell having an interior portion having at least one recess having an upper control surface, an exterior portion, and a second hinge member along a second housing shell edge engageable with the first hinge member wherein the second housing shell is rotatable about the first hinge member. The cable-shaving tool includes a blade removably securable between a blade holder and a blade support surface on the housing lid, the blade extending within a portion of the recess and a movable cable ramp disposed in the cavity of the bottom housing for urging the cable toward the blade when the second housing shell is in a closed position.
Patent WO-2022232137-A1 (WO)
Inventor: DEFREITAS KENNETH
IPC: A61B6/04
Filed: 2022-04-26
Abstract: A method of imaging a breast of a patient with a breast imaging system includes supporting the breast on a breast support platform. A compressive force is applied to the breast with a breast immobilization element including a rigid substrate, a foam compressive element secured below the rigid substrate, and a force sensor. The foam compressive element is in contact with the breast during application of the compressive force. A force signal is detected at the force sensor based on the applied compressive force. A compressed thickness of the breast proximate the force sensor is determined based at least in part on the detected force signal at the force sensor. An automatic exposure control is set based at least in part on the determined thickness of the breast proximate the force sensor.
Patent WO-2022235465-A1 (WO)
Title: Tire carrier and bedslide attachment systems
Inventor: DYLEWSKI EUGENE A
IPC: B60R11/00
Filed: 2022-04-27
Abstract: A modular accessory attachment system for a tire carrier, a bike rack, container, or other structure that can be selectively attached to either a bedslide, cargo box bed, or tailgate hitch, is provided. The modular accessory attachment system may include a plurality of receivers disposed through the deck of the bedslide. Correspondingly sized posts may be extend from the tire carrier, bike rack, other racks, or accessories, and be disposed into the receivers. Pins, detents, or other like attachment means may be employed to secure the posts to the receivers.
Patent WO-2022232304-A1 (WO)
Inventor: UHLING THOMAS F
IPC: H04W84/00
Filed: 2022-04-27
Abstract: A network system includes a main network implementing a conventional network protocol and a BPD subtree implementing a custom network protocol. The main network comprises a plurality of MPD nodes, the conventional network protocol being configured for MPD nodes. The BPD subtree comprises a plurality of BPD nodes, the custom network protocol being configured for BPD nodes. The custom network protocol defines smaller and simpler subtrees relative to the conventional network protocol. As a result, the custom network protocol defines less complex functions relative to the conventional network protocol, including functions for discovery, messaging, and loop management. A root node of the BPD subtree is connected with an MPD node of the main network and one or more descendant nodes of the BPD subtree. The root node implements the conventional network protocol and the custom network protocol.
Patent WO-2022235678-A1 (WO)
Title: Human anti-coronavirus peptide vaccines and methods of their use
Inventor: KAUMAYA PRAVIN T P
IPC: C07K14/165
Filed: 2022-05-03
Abstract: Disclosed are compositions related to modified coronavirus S protein peptides, synthetic coronavirus S protein peptides, chimeric coronavirus S protein peptides, anti- coronavirus S protein antibodies and methods of treating coronavirus infections using said peptides or antibodies.
Patent WO-2022241090-A1 (WO)
Title: Methods and compositions for treating liver disease
Inventor: MARH JOEL
IPC: C12N5/077
Filed: 2022-05-12
Abstract: Provided are methods of treatment comprising administering to a subject, in need thereof, a therapeutically effective amount of activated stem cells to the affected tissue or organ. The methods described herein are treatment modalities employing mesenchymal stem cells (MSC) in the treatment of mammals, as well as MSC purification and formulation methods including the "activation" or "preconditioning" of stem cells.
Patent WO-2022241175-A1 (WO)
Title: Substituted heterocyclic compounds
Inventor: SPERGEL STEVEN H
IPC: A61P29/00
Filed: 2022-05-13
Abstract: There are disclosed compounds of the following formula I: or a stereoisomer or pharmaceutically acceptable salt thereof, wherein all substituents are as defined herein, which are useful in the modulation of IL-12, IL-23 and/or IFNα, by acting on Tyk-2 to cause signal transduction inhibition. The compounds of the invention may be useful for treating neurodegenerative diseases or disorders.
Patent WO-2022245969-A1 (WO)
Inventor: NORLING BRIAN L
IPC: A61M5/28
Filed: 2022-05-18
Abstract: A cartridge-based injection system that can include a chemiluminescent matrix disposed within the cartridge. The cartridge may be combined with an aspirating syringe or a self- aspirating syringe to provide enhanced visualization of blood from a patient's injection site when the syringe first aspirates prior to injection of the contents of the cartridge into the patient. Enhanced visualization of blood can thereby indicate the placement of an aspirating syringe's needle to be within the patient's vasculature. With such an enhanced visualization, the user of the aspirating syringe may remove the needle to prevent accidental injection of the cartridge contents into the patient's vasculature.
Patent WO-2022246024-A1 (WO)
Title: Lidar with microlens array and integrated photonic switch array
Inventor: SEOK TAE JOON
IPC: G01S17/88
Filed: 2022-05-19
Abstract: The present disclosure is directed to imaging LiDARs with optical antennas fed by optical waveguides. The optical antennas can be activated through an optical switch network that connects the optical antennas to a laser source to a receiver. A microlens array is positioned between a lens of the LiDAR system and the optical antennas, the microlens array being positioned so as to transform an emission angle from a corresponding optical antenna to match a chief ray angle of the lens. Methods of use and fabrication are also provided.