baber/WOPTO huggingface dataset:
Patent LV-12712-A (LV)
Inventor: RAGHAVAN KRISHNASWAMY S
IPC: A61K47/48
Filed: 2001-07-04
Abstract: A ras-farnesyltransferase inhibitor complex formed of ras-farnesyltransferase inhibitor or a pharmaceutically acceptable salt thereof, of formula (I), wherein n is 0 or 1; R1 is selected from Cl, Br, phenyl, pyridyl or cyano; R2 is aralkyl; R3 is selected from lower alkyl, aryl or substituted aryl or heterocyclo; Z1 is selected from CO, SO2, CO2 or SO2NR5, R5 is selected from hydrogen, lower alkyl or substituted alkyl; and sulfobutylether-7-beta;-cyclodextrin or 2-hydroxypropyl-beta;-cyclodextrin is provided. The complex has unexpectedly high aqueous solubility of the ras-farnesyltransferase inhibitor and is useful for its intravenous delivery to humans with cancer. Also provided is a method for forming the complex. The ras-farnesyltransferase inhibitors are useful as anti-tumor agents
Patent LV-14963-A (LV)
Title: Corrector of endothelial dysfunction
Inventor: KALVIŅŠ Ivars
IPC: A61K31/22
Filed: 2013-06-28
Abstract: Invention relates to synergistic therapeutical composition comprising meldonium acetylsalicylic acid addition salt as a corrector of endothelial disfunction and an inhibitor of HMG-CoA reductase for use in prevention and/or treatment of thrombosis.
Patent MD-980080-A (MD)
Title: Device for semi-finished items compacting by means of rolling
Inventor: CIUPERCĂ RADU
IPC: B21D37/12
Filed: 1998-03-27
Abstract: The invention relates to machine building and may be used in devices for metals processing by pressure.The device comprises a hollow frame in which it is installed a central gear wheel being in engagement with a planet pinion having rollers which is dislocated in the inclined central bevel gear hub. Into the planet pinion hub it is installed a tool the deformation sides of which are arranged under an angle relative to the planet pinion middle plane. The tool deforms the semi-finished item which obtains the axial displacement from the bar. The central bevel gear rotation is performing into the spherical-tridimensional movement of bevel gear with the tool obtaining the additional movement from the engagement with the central gear wheel which owing to the tool deformation sides inclination is performing into the helicoidal movement.
Patent TR-22403-A (TR)
IPC: B22C9/06
Filed: 1984-07-03
Abstract: A process for producing a casting mould with chemically bound moulding material using a pattern is intended to make it possible to forego the use of clay-bound sand, in particular for the mass production of cast members, and to provide a casting mould of adequate gas permeability, which is simple to produce, with a low level of consumption of moulding material, and inexpensive, and which also provides a high level of casting quality wth a low degree of environmental pollution. For that purpose, the moulding material which has become pourable or fluid due to the operation of casting a cast member is removed from a first casting mould comprising a single moulding material, whereas the remaining portion of the moulding material is left, and the hollow space formed when the pattern is re-fitted is filled with moulding material. In addition, the moulding material which has been reduced in strength may be also removed, being for example blown or brushed out.
Patent YU-109589-A (YU)
Title: Resetka za radiografsko snemanje
Inventor: LUCIJAN MIKLAVCIC
Filed: 1989-05-26
Abstract: REŠETKA ZA RADIOGRAFSKO SNEMANJE. Rešetka po izumu ima v neprosojnem okviru 11, ki je z držali 2, 2' premično pritrjen na skenirni vodili 3, 3', vporedni z vzdolžno osjo X rešetke 1, in na prečno vodilo 4, izvedeno pravokotno skoznjo odprtino 11' z navzdolnjim in navzgornjim, glede na smer skenirnega giba S, robom 11'a oziroma 11'b, ki sta pravokotna na os X, in je značilna po tem, da navzdolnja bočna stranica 12' po dveh sosednjih izmed neprosojnih lamel 12, pritrjenih v okvir 11 in prehajajočih z medsebojno vzporednimi vzdolžnimi osmi A preko odprtine 11', seka robova 11'a, 11'b v točkah T oziroma T', enako oddaljenih od osi X, in da se navzdolnje bočne stranice 12' lamel 12, katerih vzdolžne središčne ravnine L se v podaljšku sekajo v konvergenčni premici CL, v podaljšku sekajo v navzgornji decentrirani premici in se navzgornje bočne stranice 12" lamel 12 sekajo v navzdolnji decentrirani premici.
Patent YU-59901-A (YU)
Title: 3-phenylpyridine derivatives and their use as nk-1 receptor antagonists
Inventor: BOES MICHAEL
IPC: C07D213/81
Filed: 2000-02-15
Abstract: The invention relates to compounds of formula (I) wherein R is hydrogen, lower alkyl, lower alkoxy, halogen or trifluoromethyl; R1 is hydrogen or halogen; or R and R1 may be together -CH=CH-CH=CH-; R2 is hydrogen, halogen, trifluoromethyl, lower alkoxy or cyano; R3 is hydrogen, lower alkyl or form a cycloalkyl group; R4 is hydrogen, -N(R5)2, -N(R5)S(O)2-lower alkyl, -N(R5)C(O)R5 or a cyclic tertiary amine of the group (a); R5 is, independently from each other, hydrogen, C3-6-cycloalkyl, benzyl or lower alkyl; R6 is hydrogen, hydroxy, lower alkyl, -N(R5)CO-lower alkyl, hydroxy-lower alkyl, cyano, -CHO or a 5- or 6 membered heterocyclic group, optionally bonded via an alkylene group, X is -C(O)N(R5)-, -(CH2)mO-, -(CH2)mN(R5)-, -N(R5)C(O)-, or -N(R5)(CH2)m-; n is 0-4; and m is 1 or 2; and to pharmaceutically acceptable acid addition salts thereof. It has been shown that the above mentioned compounds have a good affinity to the NK-1 receptor.
Patent AU-1408301-A (AU)
Title: Method and system for identifying encoding/decoding information in a mobile radio network
Inventor: KALLIO HANS
IPC: H04L12/56
Filed: 2000-11-27
Abstract: A method and system for operating a mobile radio network in a packet switched mode in which a PCOMP index and a DCOMP index are separately used to specify identification values regarding encoding of data for transmitting so as to allow a receiving end to decode the data according to the identification values. The method comprises the steps of providing an OPT index representative of the PCOMP index and the DCOMP index, and providing an OPT field in the transmitted data, for conveying the OPT index to the receiving end. Preferably, the OPT field is extendable to specify other identification values for encoding/decoding, if a further index is used to specify such values.
Patent AU-1477800-A (AU)
Title: Percutaneous material removal device and method
Inventor: FINDLAY THOMAS R III
IPC: A61B17/22
Filed: 1999-11-11
Abstract: A catheter-based material removal device includes an elongated tube having a distal material removal tip thereon. The material removal tip includes a one- or two-piece housing affixed to the tube, and a rotating member therein. The rotating member includes a screw thread for coarsely chopping material received within the housing and an outwardly projecting flange for finely chopping the material. The housing includes at least one shearing member located axially adjacent the outwardly projecting flange. The shearing member has a relatively small circumferential size and a shearing edge that removes any material buildup on the axially-facing surface of the flange. Two shearing members may be provided, one each on both the proximal and distal sides of the flange. There may be three flanges restrained within a groove formed with the housing. The shearing members are located adjacent to the groove and may have the shape of teeth, with arcuate inner faces spanning an included angle through the center of the housing of about 25 degrees. The shearing member on the housing extends inward from a lumen wall and the shearing edge thereon has a radially oriented portion and a curvilinear portion blending into tangency with the lumen wall.
Patent AU-1492395-A (AU)
Title: Screw made of biodegradable material for bone surgery purposes, and screwdriver suitable therefor
Inventor: STAHELIN ANDREAS C
IPC: A61B17/86
Filed: 1995-03-17
Abstract: The screw (1) has an elongated screw body (2), which extends in the direction of a longitudinal axis (L) between proximal (3) and distal (4) ends. An outer surface (5) of the screw body is provided with an outer thread (6) coaxial to the longitudinal axis which is intended for guiding and holding the screw in the bone material of a patient. In the screw body an elongated channel (7) coaxial to the longitudinal axis is provided, which at the proximal end is open for accommodation of a shaft (8) of a screwdriver (9) intended for tightening the screw. <IMAGE>
Patent AU-1498999-A (AU)
Title: Method for transmitting measurement reports in a mobile communications system
Inventor: REYNOLDS PAUL
IPC: H04W72/08
Filed: 1998-12-11
Abstract: A service node is provided in a mobile communications network which collects radio link measurement reports which are transmitted to the service node by mobile stations. The mobile stations transmit the measurement reports in encapsulated form, in the form of SMS messages, in order to prevent the interception of the measurement report by the serving base station. The service node is able to perform handover decision algorithms using the measurement reports collected from the mobile stations in order to determine appropriate radio access nodes to be allocated to the mobile stations.
Patent AU-1650588-A (AU)
Title: Apparatus for removing grit
Inventor: WEIS FRANK G
IPC: B01D21/00
Filed: 1988-05-20
Abstract: A grit selector having an upper settling chamber (11) and a lower grit storage chamber (12). The settling chamber (11) communicates with the grit storage chamber (12) through an opening (15) in a transition surface (13) therebetween. An influent flume (41) directs influent liquid directly into a lower portion of the settling chamber (11). An effluent flume (52) withdraws effluent liquid from an upper portion of the settling chamber (11). The influent flume (41) and effluent flume (52) have a common centerline with the effluent flume (52) being positioned at an elevation above the influent flume (41). A baffle member (45) extends into the settling chamber (11) for directing the influent liquid stream outwardly towards a lower portion of the periphery of the settling chamber (11) (Fig. 1).
Patent AU-1752292-A (AU)
Title: Wrinkled absorbent particles of high effective surface area having fast absorption rate
IPC: C08F220/18
Filed: 1992-03-18
Abstract: The subject invention pertains to large particle size, attrition-resistant, continuous, but wrinkled, high surface area aqueous fluid absorbent polymers, preferably of a crosslinked acrylic acid or acrylate. These absorbents have absorption rates superior to spherical absorbents. The subject invention further pertains to a process of preparing such polymers comprising suspension polymerization with an at least partially oil phase soluble initiator. The subject invention further pertains to absorbent structures containing such polymers, and to the use of such polymers therein.
Patent AU-1791997-A (AU)
Title: Supported catalyst systems
Inventor: LYNCH JOHN
IPC: C08F10/00
Filed: 1997-02-19
Abstract: Supported catalyst systems are obtainable byA) reaction of an inorganic carrier with a metal compound of the general formula I whereM1 is an alkali metal, an alkaline earth metal or a metal of main group III or IV of the Periodic Table,R1 is hydrogen, Ch1-C10-alkyl, C6-C15-aryl, alkylaryl or arylalkyl each having 1 to 10 carbon atoms in the alkyl radical and 6 to 20 carbon atoms in the aryl radical,R2 to R4 are each hydrogen, halogen, C1-C10-alkyl, C6-C15-aryl, alkylaryl, arylalkyl, alkoxy or dialkylamino each having 1 to 10 carbon atoms in the alkyl radical and 6 to 20 carbon atoms in the aryl radical,r is an integer from 1 to 4 ands, t and u are integers from 0 to 3 the sum r+s+t+u corresponding to the valency of M1,B) reaction of the material obtained according to A) with a metallocene complex in its metal dihalide form and a compound forming metallocenium ions andC) subsequent reaction with a metal compound of the general formula II whereM2 is an alkali metal, an alkaline earth metal or a metal of main group III of the Periodic Table,R5 is hydrogen, C1-C10-alkyl, C6-C15-aryl, alkylaryl or arylalkyl each having 1 to 10 carbon atoms in the alkyl radical and 6 to 20 carbon atoms in the aryl radical,R6 and R7 are hydrogen, halogen, C1-C10-alkyl, C6-C15-aryl, alkylaryl, arylalkyl or alkoxy each having 1 to 10 carbon atoms in the alkyl radical and 6 to 20 carbon atoms in the aryl radical,o is an integer from 1 to 3 andp and q are integers from 0 to 2 the sum o+p+q corresponding to the valency of M2.
Patent AU-1892701-A (AU)
Title: Modified polytrimethylene terephthalate
Inventor: KATO JINICHIRO
IPC: C08G63/688
Filed: 2000-12-15
Abstract: The present invention provides poly(trimethylene terephthalate) copolymerized with ester-forming sulfonate and a fiber thereof. The polymer of the present invention is high in melting point, small in loss of melting viscosity and has a high molecular weight. The fiber of the present invention is high in toughness, excellent in whiteness and dyeable with a cationic dye, whereby it is useful for clothing, carpets or non-woven sheets, etc.
Patent AU-1993099-A (AU)
Title: A method and an apparatus for separation of foremilk
Inventor: PETTERSON TORBJORN
IPC: A01J5/017
Filed: 1998-12-21
Abstract: The present invention relates to a method for automatic separation of foremilk and/or milk not suitable for consumption from the milk line system of a milking plant and an apparatus for carrying out said method. A separating device (44) is arranged at the ends of a milk line (52) and a test milk line (56), said milk lines being parallel. The separating device is designed with a damper means (48) attached to a cup (46). When milk is fed through the outlet (16), the cup (46) is filled up and its weight pivots the separating device from a first position, in which the inlet to a milk line (52) is closed by means of the damper mean, to a second position, in which the milk in cup is poured into a test milk line (56) and the damper means is lifted off the inlet (50|) to the milk line (52).
Patent AU-2021299-A (AU)
Title: Trialkyl-lock-facilitated polymeric prodrugs of amino-containing bioactive agents
Inventor: GREENWALD RICHARD B
IPC: A61K31/136
Filed: 1998-12-29
Abstract: The present invention is directed to double prodrugs containing polymeric-based transport forms. These polymeric prodrugs are preferably of the formula: wherein: B is a leaving group or a residue of an amine-containing target moiety; G is or CH2; Y1-2 are independently O or S; M is X or Q; where X is an electron withdrawing group and Q is a moiety containing a free electron pair positioned three to six atoms from C(=Y2); R1, R4, R7, R8, R9, R10 and R13 are independently selected from the group consisting of hydrogen, C1-6 alkyls, C3-12 branched alkyls, C3-8 cycloalkyls, C1-6 substituted alkyls, C3-8 substituted cycloalkyls, aryls, substituted aryls, aralkyls, C1-6 heteroalkyls, substituted C1-6 heteroalkyls; R2, R3, R5 and R6 are independently selected from the group consisting of hydrogen, C1-6 alkyls, C1-6 alkoxy, phenoxy, C1-8 heteroalkyls, C1-8 heteroalkoxy, substituted C1-6 alkyls, C3-8 cycloalkyls, C3-8 substituted cycloalkyls, aralkyls, aryls, substituted aryls, such as aryls substituted with halo-, nitro- and cyano-; carboxy-, C1-6 carboxyalkyls and C1-6 alkyl carbonyls; (m) is zero or one; (n) is zero or a positive integer; (p) is zero, one or two; and R11 is a substantially non-antigenic polymer. The first prodrug is generated when the polymeric portion of the double prodrug is cleaved and the parent molecule is generated rapidly thereafter in vivo, as a result of a trialkyl lock type lactonization-type reaction.
Patent AU-2042600-A (AU)
Title: Detectable earplug and method of manufacture thereof
Inventor: FALCO ROBERT N
IPC: A61F11/10
Filed: 1999-12-06
Abstract: An earplug including a foam body and a detectable insert completely encased by the foam body. The earplug is manufactured by forming a channel in the foam body and placing the detectable insert in the channel. The channel is formed by deforming the foam body using a punch. The foam body is made from a slow recovery foam which returns to its original shape thereby encapsulating the detectable insert within the foam body. In an alternative embodiment, the insert is projected into the foam body and the foam body recovers to encapsulate the insert.
Patent AU-2055001-A (AU)
Title: Method and apparatus for controlling the strategy of compounding pharmaceutical admixtures
Inventor: KIRCHER JOSEPH J
IPC: G06Q50/22
Filed: 2000-12-01
Abstract: A method and apparatus for controlling the compounding of pharmaceutical parenteral admixtures id disclosed. The apparatus preferably comprises a computer that contains a memory for storing instructions for operating the apparatus and for controlling compounders that prepare a prescription admixture, with the memory including data relating to a plurality of the pharmaceutical components that may be transferred to prepare the prescription admixture, and data concerning the operating characteristics of the compounders that the apparatus is adapted to control. The apparatus determines the order of admixing by general rules of admixing and by categorized compatibility groups of components, so that the number of rinses that must be done are minimized.
Patent AU-2180901-A (AU)
Title: Channel for an automobile fluid
Inventor: GUIPPE JEROME
IPC: B32B25/04
Filed: 2000-11-30
Abstract: A transport tube for transporting a motor vehicle fluid, in particular a coolant, which tube comprises:an inner layer (1) made of vulcanized elastomer material;an outer layer (2) made of thermoplastic material that withstands the coolant chemically and that is impermeable thereto; andan intermediate bonding layer (3) made of a material that is compatible with the materials of the inner and outer layers.
Patent AU-2194200-A (AU)
Title: Actuator for injection molding valve gate
Inventor: STEIL FREDERICK G
IPC: B29C45/28
Filed: 1999-12-17
Abstract: A valve for controlling the flow of fluent plastic material from an injection molding machine to a mold cavity. The valve includes an axially slidable valve pin that interacts with a material outlet to control flow through the valve selectively. The valve pin is actuated by an eccentric cam arrangement that positively drives the valve pin between positions where it is engaged with or disengaged from the material outlet. The cam acts on the valve pin only in an axial direction to avoid wear occasioned by side loads imposed on a valve pin.
Patent AU-2227997-A (AU)
Title: Fluid flow connector, fluid pressure mechanism and product tank lid for fluids such as adhesives
Inventor: GORDON FERGAL ANTHONY
IPC: F16J13/02
Filed: 1997-03-04
Abstract: Provided is a lid for a product tank including an upper face (301), a lower face (302) and a plurality of sides (300), the sides (300) being concave and the intersection of the sides (300) defining a corner of the lid, each corner being provided with a hook-shaped ring (303) which defines a slot (304) into which studs on the product tank can be received.
Patent AU-2265100-A (AU)
Title: Forehead support for facial mask
Inventor: GUNARATNAM MICHAEL KASSIPILLAI
IPC: A61M16/06
Filed: 2000-03-29
Abstract: A forehead support (10) for a respiratory mask, said forehead support (10) including a pair of arms (22), wherein: the arms (22) are adapted to pivot relative to each other; the arms (22) are selectively lockable at two or more angular positions relative to each other, and each arm (22) includes a base structure configured for coupling with a frame of a respiratory mask wherein each of the arms (22) includes first and second lateral ends, the respective first lateral ends being juxtaposed adjacent one another and the second lateral ends being positioned remote from one another when the arms are positioned in the two or more angular positions.
Patent AU-2350595-A (AU)
Title: Pyrazolo and pyrrolopyridines
Inventor: CHEN YUHPYNG L
IPC: A61P25/28
Filed: 1995-05-18
Abstract: This invention relates to compounds of the formulawherein A, B, R3, R4, R5 and R7 are as defined herein, and to their use in the treatment of stress-related diseases.
Patent AU-2389697-A (AU)
Title: Process for the electrochemical synthesis of n-acetylcysteine from cystine
Inventor: RIERA ANTONIO ALDAZ
IPC: C25B3/25
Filed: 1997-05-07
Abstract: The process comprises:   (A) obtainment of N-acetyl-cysteine from L-cystine, by means of the following steps:     (i) acetylation of L-cystine to produce N-acetyl-cystine; (ii) electroreduction and desalination by electrodialysis of the N-acetyl-cystine thus produced to give N-acetyl-cysteine; or   (B) obtainment of N-acetyl-cysteine from L-cystine, by means of the following steps:   (i) acetylation and desalination of L-cystine to produce N-acetyl-cystine; (ii) electroreduction of N-acetyl-cystine which may or may not come from the preceding step (i) to produce N-acetyl-cysteine;   (C) obtainment of N-acetyl-cysteine from L-cystine by means of the following steps:     (i) electroreduction of L-cystine to produce L-cysteine; (ii) acetylation and desalination by electrodialysis of L-cysteine, which may or may not come from the preceding   step (i) to produce N-acetyl-cysteine.     The N-acetyl-cysteine thus obtained has important uses in the pharmaceutical sector. <IMAGE>
Patent AU-2490602-A (AU)
Title: Method for pretreating crude oils and raw fats for the production of fatty acid esters
Inventor: BRUNNER KARLHEINZ
IPC: C11B3/06
Filed: 2001-11-29
Abstract: A method for the production of fatty acid esters of primary and/or secondary alcohols from raw, unpurified oils or fats containing free fatty acids and slimy substances or from waste oils loaded with free fatty acids from the food industry. Acidic catalytic esterification is performed on the free fatty acids along with extensive deactivation of the slimy substances present with respect to the disadvantageous emulsion-forming property thereof, whereby a water-free primary and/or secondary alcohol and a highly acidic hygroscopic catalyst are added to the starting substance in the form of crude oil or fat or waste oil, the reaction product is rinsed with glycol from a prior alkaline transesterification, whereupon alkaline transesterification occurs for the unmodified remaining glyceridically bound fatty acids in the reaction product of the acidic-catalytic esterification process.
Patent AU-2883192-A (AU)
Title: Combined cellular and immunosuppressive therapies
IPC: A61K35/12
Filed: 1992-10-14
Abstract: Novel regimens are provided for administering foreign genetically modified allogeneic cells to a host by combining the administration of the cells with a reduced regimen of an immunosuppressive agent. Particularly, cells having a reduced level of Class I MHC antigens may be employed in a variety of cellular therapy situations, where foreign cells are engrafted to treat diseased states.
Patent AU-2958197-A (AU)
Title: A window regulator, particularly for vehicle windows
Inventor: PERAZZO PIERLUIGI
IPC: E05F11/48
Filed: 1997-05-20
Abstract: A cable transmission connected to a drive unit comprises a pair of flexible sheaths (32, 34) each having a first end anchored to a housing of the drive unit and a second end anchored to a slide (22) which supports a pane and is slidable along a track (20). A flexible cable which extends around a drum of the drive unit comprises two branches (46, 48) slidable in the respective sheaths (32, 34). The slide (22) has a pair of internal ducts (50, 52) for guiding the branches (46, 48) of the cable, the ducts extending between inlet openings, to which the second ends of the sheaths (32, 34) are anchored, and respective opposed outlets facing towards respective opposite ends of the track (20). The two opposite ends of the cable are anchored to the respective ends of the track (20) so that respective portions (46a, 48a) of the cable disposed between the respective outlets and the respective ends of the track (20) extend parallel to the track.