baber/WOPTO huggingface dataset:
Patent CA-2527658-A1 (CA)
Title: Methods and compositions for interferon therapy
Inventor: CONNOR ROBERT
IPC: A61K48/00
Filed: 2004-06-04
Abstract: Methods and pharmaceutical compositions for administering protein or gene therapy to tissues or organs having an epithelial cell layer are provided. A  protein or nucleic acid encoding the protein is administered to the target tissue or organ in combination with treatment with a delivery enhancing agent which increases the delivery of the interferon or nucleic acid to the cells of the target tissues or organs. The methods and combinations are particularly useful in the treatment of cancers and other conditions responsive to interferon therapy. An exemplary method comprises the transurethral intravesical administration to the bladder of a therapeutically effective amount of a pharmaceutical composition comprising an alpha-interferon or a gene delivery system encoding the interferon and SYN3 or a SYN3 homolog or analog. In the urinary bladder, as much as a 10 to 1000 fold increased in interferon levels and activity may be observed with the use of a SYN3 formulation as opposed to a PBS formulation of the same interferon protein or interferon gene delivery system.
Patent CA-2529156-A1 (CA)
Title: Unified player rewards
Inventor: FINE RANDALL A
IPC: G06F/
Filed: 2004-06-14
Abstract: In a casino enterprise, players earn reward credits from their betting activity at gaming machines, tables and devices. Base credits are earned by players at a fixed rate according to their coin-in; bonus credits are earned at a variable rate as a function of their worth as players to the casino or the property at which they are gaming. Preferably the fixed credit rate is published to the players while the variable rate(s) are not disclosed. The earned credits are combined for the player into a single account balance, from which the player can redeem credits for comps.
Patent CA-2529878-A1 (CA)
Title: Pyrazole derivative, drug composition containing the same and production intermediate therefor
Inventor: FUJIKURA HIDEKI
IPC: A61K45/00
Filed: 2004-06-15
Abstract: A pyrazole derivative capable of expressing an excellent human sodium/glucose cotransporter (SGLT) inhibiting activity, which pyrazole derivative is useful as a preventive, progress inhibitor or therapeutic agent for diseases (diabetes mellitus, after-meal hyperglycemia, impaired glucose tolerance, diabetic complications, etc.) attributed to excess introjection of at least one carbohydrate selected from among glucose, fructose and mannose. The pyrazole derivative is represented by the general formula: (I) [R1 is H, a substituted or unsubstituted C1-6 alkyl, etc.; one of Q and T is a group selected from among: and while the other is -Z-Ar (wherein Z is -O-, -S-, etc.  and Ar is a substituted or unsubstituted C6-10 aryl, etc.), etc.; and R is a substituted or unsubstituted C3-8 cycloalkyl, a substituted or unsubstituted C6-10 aryl, etc.]. There are further provided a pharmacologically acceptable salt of the pyrazole derivative, a prodrug thereof and a drug composition containing them. There are still further provided a medical use thereof and a production intermediate therefor.
Patent CA-2531983-A1 (CA)
Title: Composite flexible transpirable device formed from separate layers of textile material joined together by a layer of adhesive polymer
Inventor: PINNA MARCO
IPC: A61M37/00
Filed: 2006-01-04
Abstract: A flexible transpirable composite device formed from two or more layers of textile material securely joined together, characterised in that said joining is achieved by a layer of a transpirable adhesive polymer completely free of solvents interposed between two adjacent layers of textile material, at least one substance having pharmacological or cosmetic activity being advantageously dispersed within the polymer.
Patent CA-2532321-A1 (CA)
Inventor: LUKAS THOMAS
IPC: A01D41/12
Filed: 2006-01-05
Abstract: A vehicle for supporting a crop picking head attached to a self-propelled harvester during over-the-road transportation in order to reduce the load on the wheels of the harvester in order to meet regulatory requirements. The vehicle is attached to the crop picking head in preparation for road travel and detached before harvesting a field. The vehicle features a mount and at least one wheel supported downward from the mount. Furthermore, the wheel is suspended from the mount through a spring element capable of absorbing irregularities in the road surface. Preferably the spring element is a hydraulic cylinder connected to a pressure reservoir, wherein the pressure reservoir operates independently of the harvester's hydraulic system, provides damping for the hydraulic cylinder, and may be set at various pressures based on the load and road conditions.
Patent CA-2534534-A1 (CA)
Title: Methods and apparatus for accessing presence information
Inventor: DAY MARK STUART
IPC: G06F15/16
Filed: 2004-08-27
Abstract: A presence server provides presence information to content subscribers via unicast transmission of the presence information. In the case where the presence server receives, from a subscriber, a subscription request for presence information having a relatively large number of subscribers, the presence server directs the content subscriber to a multicast transmission channel. The content subscriber, in turn, accesses the presence information via the multicast transmission channel. By directing content subscribers toward the multicast transmission channel, the presence server conserves connection resources associated with the presence system, thereby allowing the presence system to distribute presence information with a relatively high level of speed and efficiency. Furthermore, by directing content subscribers toward the multicast transmission channel, the presence server minimizes the costs associated with adding new subscribers to the presence system.
Patent CA-2537557-A1 (CA)
Title: Extendable improved cleaning system and method
Inventor: GERARD CHRISTIAN
IPC: A46B7/02
Filed: 2004-09-01
Abstract: A system (100) for cleaning includes a handle (100a) and a head (110) having a cleaning surface. The head (110) is connected to the handle (100a) and is extendable to selectively widen or narrow the cleaning surface. A gear (302) is fixedly connected to the handle (100a) and rotatingly connected to the head (110), so that twist of the handle (100a) rotates the gear (302). A first series of extension gears (306a-c) operably connect to the gear (302), and a second series of extension gears (304a-b) also operably connect to the gear (302). Rotation of the gear (302) via the handle (100a), rotates the first series (306a-c) and the second series (304a-b). A first head extension (310) is operably connected to the first series (306a-c), such that rotation of the first series (306a-c) swings the first head extension (310) into laterally aligned extension of the head (310). A second head extension (312) is operably connected to the second series (304a-b), such that rotation of the second series (304a-b) swings the second head extension (312) also into laterally aligned extension of the head (110). In such manner, twist of the handle (100a) rotates the gear (302), causing the first series (306a-c) and the second series (304a-b) to rotate, thereby swinging the first (310) and second head (312) extensions into laterally extended alignment in order to selectively widen (and conversely narrow) the cleaning surface of the head (110).
Patent CA-2539114-A1 (CA)
Title: Protective garment having cuff-forming member
Inventor: GRILLIOT MARY I
IPC: A62B17/00
Filed: 2006-03-09
Abstract: For a firefighter or for an emergency rescue worker, a protective garment comprises an arm-covering or leg-covering sleeve, which comprises an outer shell, a lining system within the outer shell, a wristlet or an anklet, which is attached non-detachably to the lining system, and a cuff forming member, which is attached non-detachably to the lining system, which extends beyond the lining system, and which is attached detachably, as via a hook-and-loop fastening device, to an outer or inner surface of the outer shell. The cuff forming member can be thus attached at any location within a range of possible locations along the garment sleeve. The cuff forming member, if visible at the cuff end of the outer shell, provides a visible indication that the lining system is present.
Patent CA-2540320-A1 (CA)
Inventor: KAO CHIUANLIANG
IPC: G06Q50/12
Filed: 2006-03-14
Abstract: rhe invention is an all-in-one and quality assurance control loop system for the process of Restaurant Operation. It has interfaces and expression of restaurant information on a website. This website will include marketing applications for restaurants such as games, auctions, message banners, job portals, event boards, broadcasting systems, fan group forming, chat room, Instant Messenger, and E-invite. The system would have a Marketing Interface and approach which would include a Restaurant BLOG and My Kitchen/My Kitchen BLOGs for the chefs. The system would have a Cross Reference and an artificial intelligent Smart Suggestions of restaurants for a user. The system would include a calendar tool, event planner, and coupon collections to allow a user to schedule their visit to the restaurant. The system would have customer/Restaurant Interactive communication channels by E-mail, chat room, SMS, and other such communication methods.
Patent CA-2541453-A1 (CA)
Title: Davit assembly
Inventor: CASEBOLT SCOTT C
IPC: B29C70/68
Filed: 2006-03-31
Abstract: A davit assembly comprises a leg having an inner portion and an outer portion, a base, a support, and an arm. The inner portion has a first end and a second end, and the outer portion has a third end and a fourth end. The first end and the third end are secured to one another, and the inner portion extends partially along the length of the outer portion. The second end is proximate a middle portion of the outer portion.  The base includes a cavity, and the first end and the third end are secured to the base. The bushing is incorporated into the cavity of the base. The support has a bottom end and a top end, the bottom end being rotatable within the bushing and connectable to the base.  The arm is operatively connected to the top end of the support.
Patent CA-2544650-A1 (CA)
Inventor: THOMPSON ROY KELLER
IPC: H01R9/28
Filed: 2004-10-07
Abstract: Telecommunications terminal blocks for making and breaking connections with a telecommunications conductor include a unitary base that defines a body cavity having a hinge member at an end thereof. In other embodiments a base includes a hinge member on an external surface thereof. First and second connectors are mounted in the base and extend into the body cavity. A toggle member is rotatably connected to the base at the hinge member. The toggle member has first and second conductor receiving openings therein and first and second conductor passages extending from the respective openings past respective ones of the connectors. An environmental sealant material is positioned in the body cavity.
Patent CA-2548602-A1 (CA)
Title: Substituted tetrahydrocarbazole and cyclopentanoindole derivatives
Inventor: WANG ZHAOYIN
IPC: A61P11/06
Filed: 2004-12-13
Abstract: The present invention provides substituted tetrahydrocarbazole and cyclopentanoindole derivatives as antagonists of DP receptor, and as such are useful for the treatment of prostaglandin D2 mediated diseases such as rhinitis, asthma and nasal congestion.
Patent CA-2549335-A1 (CA)
Title: Extruded protective railing system
Inventor: GRANT DONALD P
IPC: E04G21/32
Filed: 2006-06-01
Abstract: A protective railing system includes at least two extruded posts, two post-mounted extruded brackets, and at least one extruded rail. The rail can be selectively installed with infinite adjustability both vertically and rotationally. Each post includes an outer tube and an inner tube with reinforcing ribs extending between the two. To secure the post to a floor, a floor-mounted anchor extends up into the inner tube. The anchor and inner tube are preferably rectangular to restrict relative rotation between the post and the anchor. When two or more rails are installed between two posts, the two rails can be interlocked, or the rails can be spaced apart to support a spacer therebetween.      In some cases, the spacer is a sign or a fabric mesh.
Patent CA-2552008-A1 (CA)
Title: Social networking software
IPC: G06Q30/02
Filed: 2006-07-07
Abstract: A method for navigating relationships between people via a social network created online via computer software. A computer system online collects information about individual users, and lets others navigate it via paths created by users of the system in a social network.  Users sign up, add friends or collegues, and others may browse their ecosystem of friends and collegues via their user created web page through direct links to their friends' profiles on the same computer system.
Patent CA-2554982-A1 (CA)
Inventor: OKAMOTO HIROSHI
IPC: A61P3/06
Filed: 2004-09-24
Abstract: The present invention aims to provide for the treatment of hyperlipidemia, arteriosclerosis and hyper-remnant-emia, and to inhibit remnant lipoportein production by adminsetering an inhibitor of CEPT (cholesteryl ester transfer protein). Said inhibitor is a compound selected from the group cosisting of compounds of formula I to fomula XXIII, and compounds selected from the group consisting of JTT-705, CP-529414, SC-795, SC-744, SC-554, SC-71952, SC-56960, SC-57201, PD-140195, WK-5341A, WK-5344B, CETI-1 (CETP Vaccine), BM99-1 and BM99-2.
Patent CA-2555376-A1 (CA)
Inventor: SAVANT-BHONSALE SMITA
IPC: C12N5/00
Filed: 2005-02-01
Abstract: The present invention encompasses methods and compositions for enhancing the growth of neural stem cells. Methods for modulating MHC molecule expression on a neural stem cell (NSC) are also included in the invention. Figure 1 is a graph depicting the proliferation of BMSCs in BMSC medium (DMEM-low glucose, 10% lot tested fetal bovine serum) or NSC medium (DMEM-F12, N2-Supplement, EGF  20 ng/ml, bFGF 10 ng/ml, heparin 8 ug/ml, penicillin-streptomycin).
Patent CA-2555665-A1 (CA)
Title: Microelectronic cleaning composition containing halogen oxygen acids, salts and derivatives thereof
Inventor: HSU CHIEN-PIN SHERMAN
IPC: C11D1/00
Filed: 2004-11-05
Abstract: Microelectronic cleaning compositions for cleaning microelectronic substrates, and particularly cleaning compositions useful with and having improved compatibility with microelectronic substrates characterized by silicon dioxide, sensitive low-.kappa. or high-.kappa. dielectrics and copper, tungsten, tantalum, nickel, gold, cobalt, palladium, platinum, chromium, ruthenium, rhodium, iridium, hafnium, titanium, molybdenum, tin and other metallization, as well as substrates of Al or Al(Cu) metallizations and advanced interconnect technologies, are provided by microelectronic cleaning compositions comprising halogen acids, salts and derivatives thereof.
Patent CA-2556107-A1 (CA)
Inventor: RODNEY PAUL F
IPC: E21B47/04
Filed: 2005-02-23
Abstract: Downhole positioning systems and associated methods are disclosed. In some embodiments, the system comprises a downhole source, an array of receivers, and a data hub. The downhole source transmits an electromagnetic positioning signal that is received by the array of receivers. The data hub collects amplitude and/or phase measurements of the electromagnetic positioning signal from receivers in the array and combines these measurements to determine the position of the downhole source. The position may be tracked over time to determine the source's path. The position calculation may take various forms, including determination of a source-to-receiver distance for multiple receivers in the array, coupled with geometric analysis of the distances to determine source position. The electromagnetic positioning signal may be in the sub-hertz frequency range.
Patent CA-2557928-A1 (CA)
Inventor: MARTIN HOWARD
IPC: A01C23/02
Filed: 2006-08-29
Abstract: A method and apparatus to be mounted upon a planter row unit for delivering liquid fertilizer to the bottom of a trench without contacting the seed to be planted is disclosed and claimed. The system as claimed and described is adapted for mounting to substantially all modern row units employing floating row units. The method and apparatus as described does not interfere with existing down pressure or seed placement systems as found on modern row crop planters. As described and implemented, the method and apparatus is more compact and lighter in weight than the prior art. The attached assembly for a seed planting unit works in combination with a seed trench opener to form a trench for the deposit of liquid fertilizer offset from and parallel to the later formed seed trench. The apparatus allows directed liquid fertilizer delivery in close proximity to the seed trench with minimal disruption of said seed trench. The attachment includes a single disk blade disposed forward of the seed trench forming unit. The single disk blade is disposed at an angle of four degrees or less from the line defining the direction of travel of the seed planting implement in combination with a furrow strap. The attachment includes a selectively adjustable down force structure and a selectively adjustable depth control mechanism.
Patent CA-2558397-A1 (CA)
Title: Ironing board cover with panel and methods of use
Inventor: GLENN JAMES L
IPC: D06F83/00
Filed: 2006-09-01
Abstract: An apparatus and methods of use for ironing board cover with a heat-resistant and waterproof panel attached to the cover, the panel having a base surface with a continuous brim and a plurality of protuberances capable of supporting an iron. The brim and the base surface form a basin. The protuberances create a gap between the iron and the base surface so that steam can condense onto the panel within the basin to be retained within the panel by the brim. The steam can also dissipate into the ambient atmosphere.
Patent CA-2559616-A1 (CA)
Inventor: VEMUGANTI GANGADHAR RAO
IPC: G01B5/06
Filed: 2006-09-12
Abstract: Système automatisé permettant de mesurer avec précision l'épaisseur d'une quantité d'échantillons de petits articles, tels que des flocons d'avoine. Le système prélève des flocons d'avoine individuels à partir d'une trémie sous vide et les transmet entre deux rouleaux de précision. Un rouleau est fixe et présente des orifices à vide pour prélever le flocon provenant de la trémie. Le second rouleau est flottant. Lorsque le flocon passe entre les rouleaux, il est aplati et le second rouleau est dévié par une quantité égale à l'épaisseur du flocon. Un système de vision artificielle pourvu d'une caméra vidéo, d'une source de lumière et d'un ordinateur mesure la déflexion du rouleau flottant. Le système de vision obtient une image de la courbure du rouleau flottant au point opposé au point de pincement des deux rouleaux. Les données provenant de la mesure peuvent être enregistrées dans l'ordinateur et traitées comme souhaité.
Patent CA-2559740-A1 (CA)
Title: Thiadiazolidinones en tant qu'inhibiteurs de la gsk-3
Inventor: DORRONSORO DIAZ ISABEL
IPC: A61K31/433
Filed: 2005-04-04
Abstract: La présente invention a trait à des composés de formule (I), dans laquelle : R¿1? est un groupe organique ayant au moins 8 atomes choisis parmi C et O, qui n'est pas en liaison directe avec l'atome d'azote via un -C(O)- et comportant au moins un noyau aromatique, et leurs compositions pharmaceutiques. Ces composés sont des inhibiteurs sélectifs de la GSK-3 et présentent une biodisponibilité améliorée. Ils sont utiles pour le traitement de maladies liées à la GSK-3, comprenant entre autres la maladie d'Alzheimer, le diabète de type II, la dépression et la lésion cérébrale.
Patent CA-2560818-A1 (CA)
Title: Polymorphic forms of (1-{3-[3-(4-cyano-3-methoxy-phenyl)ureido]-phenyl}-ethyl)-carbamic acid-2-cyano-1-ethyl-ethyl ester
Inventor: NYCE PHILIP L
IPC: C07C275/42
Filed: 2005-03-22
Abstract: The present invention relates to polymorphic forms of (1-{3-[3-(4-cyano-3-methoxy-phenyl)ureido]-phenyl}-ethyl)-carbamic acid-2-cyano-1-ethyl-ethyl ester, processes therein, pharmaceutical compositions thereof, and uses therewith.
Patent CA-2561768-A1 (CA)
Inventor: NARAYANAN PALLASSANA VENKETESS
IPC: A61L31/16
Filed: 2006-10-02
Abstract: Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism. The medical devices may be coated with any number of biocompatible materials. Therapeutic drugs, agents or compounds may be mixed with the biocompatible materials and affixed to at least a portion of the medical device. These therapeutic drugs, agents or compounds may also further reduce a biological organism's reaction to the introduction of the medical device to the organism. In addition, these therapeutic drugs, agents and/or compounds may be utilized to promote healing, including the formation of blood clots. The drugs, agents, and/or compounds may also be utilized to treat specific diseases, including vulnerable plaque.   Therapeutic agents may also be delivered to the region of a disease site. In regional delivery, liquid formulations may be desirable to increase the efficacy and deliverability of the particular drug. Also, the devices may be modified to promote endothelialization. Various materials and coating methodologies may be utilized to maintain the drugs, agents or compounds on the medical device until delivered and positioned. In addition, the devices utilized to deliver the implantable medical devices may be modified to reduce the potential for damaging the implantable medical device during deployment. Medical devices include stents, grafts, anastomotic devices, perivascular wraps, sutures and staples. In addition, various polymer combinations may be utilized to control the elution rates of the therapeutic drugs, agents and/or compounds from the implantable medical devices.
Patent CA-2563454-A1 (CA)
Title: Crth2 receptor antagonists
Inventor: SANDHAM DAVID ANDREW
IPC: A61K31/277
Filed: 2005-05-03
Abstract: There are provided according to the invention compounds of formula (I) in free or salt form, wherein R1, R2, R3, X, Y, Z, m, and n are as described in the specification, process for preparing them, and their use as pharmaceuticals.
Patent CA-2564279-A1 (CA)
Inventor: SKILLING JOHN
IPC: G01N30/72
Filed: 2005-05-03
Abstract: A mass spectrometer and method of mass spectrometry are disclosed wherein two separate samples are mass analysed and then the relative intensity, concentration or expression level of one or more components, molecules or analytes in a first sample is quantitated relative to the intensity, concentration or expression level of one or more components, molecules or analytes in a second sample. The relative quantitation is performed probabilistically without the need to resort to using internal calibrants.
Patent CA-2568588-A1 (CA)
Title: Package for personal care products comprising a shrink label
Inventor: MCCUTCHAN MICHAEL DEAN
IPC: B65D23/00
Filed: 2005-06-14
Abstract: A package for a personal care composition comprising: a bottle (2); a cap, wherein the cap is attached to the bottle; and a shrink label (1), wherein the shrink label covers at least a portion of the bottle (2) and a portion of the cap (3), and wherein the shrink label covers a gap (4) between the bottle and the cap. The package can prevent water from accumulating between the cap (3) and bottle (2) when the package is used in a wet environment, such as the shower or bath, which can lead to the formation of mold and/or mildew between the cap (3) and bottle (2). The package also can dissuade consumers in a retail store from unscrewing or otherwise removing the cap (3) from the bottle (2), which can lead to leakage of the personal care composition onto the store shelves.