baber/WOPTO huggingface dataset:
Patent PT-665234-E (PT)
Inventor: RICHARD LISOWSKY DR
IPC: C07F17/00
Filed: 1994-08-05
Abstract: Preparation of bis-cyclopentadienyl compounds of formula (I) by reacting a compound of formula (II) with a magnesium compound (III); and in a second step with a compound (IV) (CpRa)2-Q (I) CPRa (II) (R3R4)cMg (III) QXX ' (IV) Cp = cyclopentadienyl or indenyl, opt. subst; R = alkyl-, phosphine-, amine, alkylether - or arylether-group; c = is less than or equal to a which is less than or equal to 4; Q = metal bridge between the rings ((R), -Z-(R))b R<1>, R<2> = H, 1-10 alkyl, 6-10 aryl; Z = C, Si or Ge; b = 1-3 R3, R4 = H, 1-12 alkyl; C = 0-1; X,X ' = Cl, Br, I, -O- SO2R5; and R5 = 1-10 alkyl or 6-10 aryl. Also claim the use of these compounds (I) in the production of metallocenes.
Patent PT-695759-E (PT)
Inventor: PETTIT GEORGE R
IPC: A61K38/00
Filed: 1995-07-21
Abstract: Herein disclosed are several pentapeptide methyl ester derivatives of dolastatin 10, using both naturally occurring and modified amino acids. The selected modified amino acids are constituents of dolastatin 10 which is a structurally distinct peptide with excellent in vitro and in vivo antineoplastic activity. The structures of these compounds are as shown below: <MATH>       10a) R1 = i-Pr ; R = -NH(Me)2 ; R2 = -CH2CH2CH2NH-cbz   10b) R1 = i-Pr ; R = -NH (Me)2 ; <CHEM>     11a) R1 = - (CH2)4NH-cbz ; R = -NH (cbz) ; <CHEM>     11b) <CHEM>  R = -NH(cbz) ; R2 = -CH2CH2CH2NH-cbz   11c) <CHEM> R = -NH(cbz) ; R2 = -CH2-S-Me m
Patent PT-758304-E (PT)
Inventor: BAUR KARL
IPC: C02F1/02
Filed: 1995-05-04
Abstract: Oxidative treatment of a medium contg. organic components comprises (a) heating the medium, (b) heating the medium under pressure while at least periodically injecting an O2-contg. gas, and (c) adding H2O2 to the medium between steps (a) and (b) or during step (b).
Patent PT-743301-E (PT)
Inventor: NORBERT BEIER DR
IPC: C07C279/22
Filed: 1996-05-02
Abstract: Fluorine-contg. benzoylguanidine derivs. of formula (I) and their salts are new. R<1> = H, halo, A, CN, NO2, CnFmH2n+1-mOp, 2-4C alkynyl or XR<4>; R<2> = CnFmH2n+1-mOp; R<3> = H, A, halo, A, CnFmH2n+1-mOp, SOqR<6>, SO2NR<4>R<5>, Het., OR<6>, SR<6>, SHet. or NR<7>Het; R<4>, R<5> = H or A; or R<4>+R<5> = 4-5C alkenyl with one -CH2- gp. opt. replaced by O, S, NH or NA; R<6> = Ph or A; R<7> = H or A; A = 1-6C alkyl; X = O, S or NR<7>; Ph = phenyl opt. substd. by 1-3 A, OA, NR<4>R<5>, halo or CnFmH2n+1-mOp; Het. = mono- or bicyclic opt. satd. aromatic heterocyclyl having 1-4 N, O and/or S, opt. substd. by 1-3 F, Cl, Br, CnFmH2n+1-mOp, XR<4>, A, NO2, CN and/or carbonyl O, and linked via N or C to the benzoyl system; m = 1-7(max 2n+1); n = 1-3; p = 0 or 1; q = 1 or 2; and provided that R<1> = H only when R<3> = SOqR<6> or SO2NR<4>R<5>.
Patent PT-781654-E (PT)
Inventor: DEMOORE HOWARD W
IPC: B41F13/193
Filed: 1996-12-23
Abstract: Freshly printed sheets are transferred from one printing unit to another by transfer cylinders each having an ink repellent, electrically conductive, striped flexible jacket covering that is movable relative to the sheet support surface of the transfer cylinder. The jacket covering is made of a flexible fabric material that is pre-stretched, pressed flat, cut to size and treated with an ink repellent compound and is also treated with an anti-static ionic compound or is otherwise rendered electrically conductive by one or more conductive strands. Electrostatic charges carried by the freshly printed sheets are discharged through the ink repellent, electrically conductive, flexible jacket covering into the grounded transfer cylinder. A low friction, electrically conductive cylinder base covering that includes center alignment marks is secured to the transfer cylinder for engaging the flexible jacket covering. The ink repellent, electrically conductive flexible jacket covering is provided with alignment center marks and alignment stripes so that the flexible jacket covering can be precisely aligned with ease and secured over the gripper edge, tail edge and side edges of the transfer cylinder. The low frictional coefficient of the conductive cylinder base covering is further reduced by nodes and/or openings.
Patent PT-872692-E (PT)
Inventor: FARINGOSI ALVARO
IPC: F24C15/02
Filed: 1997-07-22
Abstract: Hinge for connecting doors (1b) to ovens (1,1a) and the like, which comprises a fixed arm (11) engageable with the body of the oven, a movable part (21) which is hinged on said fixed arm (11) and on which one end (23b) of a movable arm (23) is pivotably mounted, there being provided means (15) for fastening the movable arm (23) to the fixed arm (11), said fixed arm (11) having a cross-section in the form of an upturned "U", between the walls of which there is arranged an idle roller (25), and said movable arm (23) being arranged inside said fixed arm. <IMAGE>
Patent PT-912981-E (PT)
Inventor: OOMMEN THOTTATHIL V
IPC: C11C3/00
Filed: 1997-06-11
Abstract: High oleic acid triglyceride compositions that comprise fatty acid components of at least 75 % oleic acid, less than 10 % diunsaturated fatty acid component; less than 3 % triunsaturated fatty acid component; and less than 8 % saturated fatty acid component; and having the properties of a dielectric strength of at least 35 KV/100 mil gap, a dissipation factor of less than 0.05 % at 25  DEG C, acidity of less than 0.03 mg KOH/g, electrical conductivity of less than 1 pS/m at 25  DEG C, a flash point of at least 250  DEG C and a pour point of at least -15  DEG C are disclosed. An electrical insulation fluid comprising the triglyceride composition is disclosed. Electrical apparatuses comprising the electrical insulation fluid and the use of electrical insulation fluid to provide insulation in electrical apparatuses are disclosed. A process for preparing the high oleic acid triglyceride composition is disclosed.
Patent PT-927297-E (PT)
Inventor: MCGOWAN ALAN COLIN
IPC: E21C37/14
Filed: 1997-09-04
Abstract: A compressed air blasting device (1), insertable in a pre-prepared bore, has a cylindrical housing or tube (2) containing a number of air guns (4). Apertures (3) in the housing (2) direct the flow of compressed air exhausted by the air guns (4) so as to produce a build-up of pressure sufficient to weaken and displace material from the area surrounding the bore. The further enhance the effect of the device (1), the bore may be filled with water and sealed with a packer (11) mounted on the device (1) prior to blasting.
Patent PT-1044968-E (PT)
Title: 6-amino-2-oxo-pyrimidin-4-one derivatives, their preparation and their use as stabilisers for halogen-containing polymers
Inventor: FRIEDRICH HANS-HELMUT
IPC: C08K3/014
Filed: 1999-11-04
Abstract: 1-(2-hydroxyalkyl)-2-(thi)oxo-4-aminopyrimidine derivatives (I) and the corresponding oxazolidino-4-aminopyrimidones (II). Aminopyrimidones (I) and the corresponding oxazolidino-pyrimidones (II) are new. X = oxygen or sulfur; R<2> = hydrogen, 1-14C alkyl, 4-8C cycloalkyl (optionally substituted), 6-10C aryl, 7-10C aralkyl or alkaryl, or -CH2XR<4>; R<4> = hydrogen, 1-10C alkyl, 4-8C cycloalkyl (optionally substituted by an oxirane ring or by 1-3 1-4C alkyl), optionally substituted benzoyl or 2-18C acyl; R<3> = R<2>, R<4> or 2-6C alkyl with at least 1-5 hydroxy substituents and/or interrupted by 1-4 oxygen atoms, or 3-8C alkenyl.   Independent claims are also included for the following: (a) a stabilizer composition containing, per 100 weight parts (wt. pt.) chlorine-containing polymer (II), 0.01-10 wt. pt (I (II) and optionally at least one other compound (X); and (b) composition comprising (III) and the stabilizer of (a).
Patent PT-1085919-E (PT)
Inventor: HABIL STEPHAN NEES PROF DR RER
IPC: A61L27/50
Filed: 1999-06-24
Abstract: The invention concerns natural or artificial hollow organs and all their parts, in particular vessels and valves, of which the inner or luminal surface is lined with patient-autologous epithelial, in particular endothelial cells, a process for producing these hollow organs and the use of these hollow organs in surgery, in particular cardiac and vascular surgery.
Patent SG-165594-G (SG)
Title: 1-[3-(dimethylamino)propyl]-1-phenylphthalenes for the treatment of cerebrovascular disorders
Inventor: TANAKA YOSHIAKI
IPC: A61P25/28
Filed: 1994-11-16
Abstract: 1-[3-(dimethylamino)propyl]-1-phenylphthalanes of the general formula   <CHEM> wherein R<1> and R<2> each are selected from the group consisting of halogen, trifluoromethyl, cyano and R-CO-, wherein R is an alkyl radical, or a pharmaceutically acceptable acid addition salt thereof, are useful in the treatment of dementia and cerebrovascular disorders and for inhibiting platelet aggregation in patients in need thereof.
Patent IE-890109-L (IE)
Title: Use of calcium sulphate to improve fermentation of organic¹waste
IPC: C05G3/80
Filed: 1989-01-16
Abstract: The present invention refers to the use of calcium sulfate to improve fermentation of organic waste. The calcium sulfate and montmorillonite along with at least one of the phosphates are used in the present invention to improve fermentation of organic waste and/or soil quality.
[CN1045766A]
Patent IE-860120-L (IE)
Title: Ingestible aggregate comprising a hydrocolloid and substrate
IPC: A61K9/00
Filed: 1986-01-15
Abstract: The present invention relates to an ingestible aggregate comprising a pre-swelled substantially anhydrous hydrocolloid and a substrate. More particularly this invention relates to an aggregate having as a substrate a dietary fiber and/or drug wherein the composition can be administered in a therapeutically effective amount. Hydrocolloids useful include natural and modified gums, celluloses, modified celluloses, pectins, mucillages, modified starches, noncellulose polysaccharides, algal polysaccharides and mixtures thereof. The aggregate should be in the size range of about 4 to about 70 U.S. mesh. The unpleasant taste and mouthfeel of the fiber and/or drug is effectively masked and substantial hydration is delayed until the compositions reaches the stomach. The compositions are substantially more palatable, devoid of grainless, bitterness or fibrous texture. The pleasant taste of the composition encourages patient compliance with their fiber or drug therapy.
[US4747881A]
Patent IE-800210-L (IE)
Title: 9,10-ethanoanthracene derivative.
IPC: A61K31/135
Filed: 1980-02-01
Abstract: For the Contracting states : BE, CH, DE, FR, GB, IT, LU, NL, SE 1. R-(-)-alpha-[(methylamino)methyl]-9,10- ethanoanthracene-9(10H)-ethanol of the formula I see diagramm : EP0014433,P10,F1 or an acid addition salt thereof. For the designated state : AT 1. A process for the production of R-(-)-alpha-[(methylamino)methyl]-9,10-ethano anthracene-9(10H)-ethanol of the formula I or of an acid addition salt thereof, see diagramm : EP0014433,P12,F1 which process comprises a) resolving the racemic alpha-[methylamino)-methyl]-9,10-ethanoanthracene -9(10-H)-ethanol and isolating R-(-)-alpha-[(methylamino)methyl]-9,10-ethano anthracene-9(10H)-ethanol, if desired in the form of an acid addition salt, or b) reacting a compound of the formula II see diagramm : EP0014433,P12,F2 with a compound of the formula III X2 -CH3 wherein one of X1 and X2 is the amino group and the other is a reactive esterified hydroxyl group, and Y1 is a free hydroxyl group and X1 together with Y1 can also be an epoxy group and A is the 9,10-ethano anthracene-9(10H)-yl radical, or c) in a compound of the formula IV see diagramm : EP0014433,P12,F3 in which at least one of Z1 and Z2 is a removable radical and the other may be hydrogen, or Z1 and Z2 together are a divalent removable radical, and A is the 9,10-ethanoanthracene-9(10H)-yl radical, removing Z1 and/or Z2 . d) reducing a compound which differs from the compound of the formula I only in that, in said compound, a carbon atom adjacent to the nitrogen atom is attached to this latter through a double bond or is substituted by a hydroxyl group or an oxo radical, optionally together with lower alkoxy, or e) adding ethylene to R-alpha-[(methylamino)methyl]-9(10H)- anthracene-ethanol, and if desired, converting the resultant R-(-)-alpha-[(methylamino)methyl]-9,10-ethanoanthracene -9(10H)-ethanol into an acid addition salt and/or liberating the base from a resultant acid addition salt.
[EP0014433B1]
Patent IE-790295-L (IE)
Title: Metal drum
IPC: B65D8/20
Filed: 1979-02-15
Abstract: A drum comprises a cylindrical metal body portion, and an end portion which is connected to the body portion at one end or the body portion by a seam; the body portion is necked-in adjacent the seam, so that the cross-section at the seam is reduced, and the body portion is also similarly necked-in adjacent the opposite end of the body portion; the necking-in is obtained by carrying out reduction operations on the body portion.
[CA1116109A]
Patent IE-840692-L (IE)
Title: Antibiotic l 17054
IPC: C07H17/00
Filed: 1984-03-21
Abstract: The present invention is directed to a new antibiotic substance arbitrarily denominated antibiotic L 17046. This antibiotic substance is obtained from the known antibiotic substance called teicoplanin (formerly teichomycin) by chemical treatment.The new compound possesses antimicrobial activity especially against gram-positive bacteria.
Patent IE-33535-L (IE)
Title: Penicillins
IPC: C07D499/00
Filed: 1969-06-10
Abstract: 1,260,882. Penicillins. FARBENFABRIKEN BAYER A.G. 6 June, 1969 [12 June, 1968], No. 28715/69. Heading C2A. Novel carboxyl- or sulphonyl-ureido penicillins of Formula (I) and their non-toxic salts, wherein R 1 is a carboxylic or sulphonic acid acyl radical having up to 26 carbon atoms and R 2 and R 3 are the same or different and are hydrogen, alkyl which may be substituted or interrupted by hetero atoms, or optionally substituted cycloaliphatic, araliphatic, aromatic or heterocyclic radicals, or together form a cycloaliphatic or heterocyclic ring with 3 to 7 ring members which ring may be substituted or fused to other rings, are prepared by reacting a compound of Formula (II) wherein the amino and/or carboxyl groups may be protected with silyl groups, with an acyl isocyanate (V) or an N-acylcarbamic acid derivative (VI) or (VII) wherein R 1 is as above; X is halogen, -SO 3 Na, -SO 3 K, -SO 3 NH 4 , A is -O- or -S- and R 7 is an alkyl, aralkyl or cycloaliphatic radical which may be substituted or interrupted by hetero atoms, or an optionally substituted aryl or heterocyclic radical. Pharmaceutical compositions having antibiotic activity against gram-positive and gramnegative bacteria comprise a penicillin of Formula I as defined above or a non-toxic salt thereof in admixture with a pharmaceutical diluent or carrier, or in unit dosage form with or without such a diluent or carrier.
[GB1260882A]
Patent IE-890858-L (IE)
Title: Process for the synthesis of arylsulphonylakylamide
IPC: C07C311/16
Filed: 1989-03-16
Abstract: Process for the synthesis of arylsulphonylalkylamides in which an arylsulphonyl halide is placed in contact with an excess of alkylamine and an aqueous solution of alkaline agent in excess in relation to the arylsulphonyl halide and then the water and excess amine are removed from the organic phase; the arylsulphonylalkylamide is then isolated. This process is particularly suited for N-n-butylbenzenesulphonamide which is obtained in a thermally stable quality and which can be advantageously employed as a plasticiser for polyamides.
Patent FI-811681-L (FI)
Inventor: BLANKENSHIP MICHAEL GREGG
IPC: G02B6/04
Filed: 1981-06-01
Abstract: A substantially continuous method of and apparatus for forming an article suitable for an optical waveguide preform wherein the starting member is continuously removed is disclosed. The preform is formed by providing a starting member or bait and applying the particulate material to the exterior surface of the starting member to form a coating thereon. The coating is longitudinally translated while simultaneously additional particulate material is applied to the coating to form a preform body with the preform body thereafter being longitudinally translated. While longitudinally translating the preform body and applying additional particulate material to the end thereof, the starting member is continuously removed from the preform body leaving a longitudinal aperture remaining in the preform body. The particulate material may be applied by one or more burners, the output of which may be controlled to provide a predetermined desired cross sectional composition variation of the resulting preform body. The so formed preformed body may thereafter be suitably heated, consolidated, and drawn into an optical waveguide.
Patent FI-822456-L (FI)
Inventor: DALES JOHN ROBERT MANSFIELD
IPC: C07D499/04
Filed: 1982-07-09
Abstract: A process for the preparation of a penam derivative of formula (I): <IMAGE> (I)  wherein RA is hydrogen or a group of formula (Ia): <IMAGE> (Ia)  wherein X is -CO2R1, or SO3R1; R is C1-6alkyl, aryl, or heterocyclyl; R1 is hydrogen, or a pharmaceutically acceptable salt-forming ion or ester-forming radical, and R2 represents hydrogen or a pharmaceutically acceptable salt-forming ion or in vivo hydrolyzable ester-forming radical; which process comprises reacting a compound of formula (II):    <IMAGE> (II)  wherein RB is hydrogen, a removable amino blocking group, or a group of formula (IIa): <IMAGE> (IIa)  wherein Y is -CO2Rx or -SO3Rx; R is as defined with respect to formula (I) above; Rx represents an ester-forming radical, RY represents hydrogen, a salt-forming radical or a carboxyl-blocking group, and R3 represents an alkyl, benzyl, or aryl group; with methanol in the presence of copper ions; and thereafter if necessary carrying out one or more of the following steps: (i) removal of any blocking group; (ii) converting the product to a pharmaceutically acceptable salt or ester thereof.
Patent IE-39269-L (IE)
Title: Nitrocarbostyrils; pharmaceutical compositions.
IPC: C07D221/10
Filed: 1974-05-15
Abstract: 1453863 Antihistamine preparations BEECHAM GROUP Ltd 15 May 1974 [19 May 1973 22 May 1973] 24000/73 and 24317/73 Heading A5B [Also in Division C2] The invention provides pharmaceutical compositions comprising compounds of the formula I and pharmaceutically acceptable salts thereof wherein R 1 , R 2 R 3 and R 4 are hydrogen, halogen, hydroxy, nitro, alkyl, alkoxy, phenyl, benzyl, pyridyl, phenoxy, benzyloxy or any adjacent two of R 1 , R 2 , R 3 and R 4 taken together are a tetramethylene or 1, 3-butadienylene group and R 5 is hydrogen, alkyl, phenyl or benzyl wherein alkyl and alkoxy groups have 1 to 6 carbon atoms, together with one or more pharmaceutically acceptable carriers. The compositions show anti-allergic or immunological activity when administered orally, parenterally or by insufflation. The composition may contain a bronchodilator such as isoprenaline.
[GB1453863A]
Patent IE-34792-L (IE)
Title: Jointing and terminating electric cables
IPC: H02G15/00
Filed: 1970-12-04
Abstract: 1309248 Moulding electrical insulation PIRELLI GENERAL CABLE WORKS Ltd 8 Dec 1970 [11 Dec 1969] 60488/69 Heading B5A [Also in Division H2] A method of jointing or terminating electric cables comprises the steps of stripping the cable insulation, electrically connecting the cable conductors or the cable conductors and the terminals, enclosing the connection in a mould, at least over the region from which the insulation has been stripped, and introducing into the mould foamable plastics material, and filler material, the plastics material then foaming to fill the mould and encapsulate the cables. The filler material has a greater thermal conductivity than the foamed and cured plastics material. In one arrangement the filler material is introduced first followed by the foamable plastics material. In a second arrangement the filler material and the foamable plastics material are mixed initially and then introduced into the mould. In a third arrangement part of the filler material is placed in the mould and the remainder is mixed with the foamable plashes material, the mixture then being introduced. In the arrangements in which part of or the whole of the filler material is introduced first it may comprise granular material, e.g. high-density polyethylene, PVC or glass, in the form of microballoons, or a sheet or tape of mesh material, e.g. polyethylene or glass. In the third arrangement the remainder of the filler material comprises granules of a size smaller than the granules or spacings in the mesh of the first part of the filler material. These smaller granules, which are also used in the second arrangement, are carried by the foam as it expands and are distributed throughout the mould. Examples given are sand, slate, PVC or polyethylene, in flow form, or glass, in the form of microballoons. The foamable plastics material, which can be polyurethane, epoxy, polystyrene, polyester or polypropylene, is subjected to pressure as it foams, for example it may have a greater potential volume than that available for its expansion. The conductors, and, when terminating a cable, the terminals, may be insulated prior to the introduction of the foamable plastics material.
[GB1309248A]
Patent IE-41186-L (IE)
Title: Oral hygiene compositions
IPC: A01N37/40
Filed: 1975-07-14
Abstract: 1514469 Oral hygiene compositions BEECHAM GROUP Ltd 18 July 1975 [1 Aug 1974] 33951/74 Heading A5B Compositions for oral hygiene e.g. mouthwashes, toothpastes, chewing gum, comprise by weight of the composition, 0.1-5% of an antibacterial component comprising one or more pharmaceutically acceptable esters of ohydroxybenzoic acid and/or of p-hydroxybenzoic acid, 0.1-5% of a vitamin or vitamin-like component comprising one or more of aescin, rutin, panthenol, nicotinamide and vitamin E, and 0.1-5% of a surfactant, the weight ratio of antibacterial component to surfactant being from 1:5 to 5:1. Other antibacterial agents e.g. o-phenylphenol or phenoxyethanol, and other vitamins e.g. vitamins C, K and B group may be present. The surfactant is preferably anionic e.g. fatty alkyl sulphates, fatty alkyl ether sulphates, or may be cationic. The compositions may also contain anticariogenic fluorides. The preferred vehicle is an aqueous alcohol.
[GB1514469A]
Patent IE-45479-L (IE)
Title: Removing moulded material.
IPC: B29C33/44
Filed: 1977-08-31
Abstract: A device for removing molded articles and cured sprues from the cavity and cover plates, respectively, of a multi-plate multi-cavity injection mold, includes a molded article ejection unit and a sprue extraction unit which, when the molding machine is opened, are juxtaposed, respectively, to a space between the mold cover and cavity plates and to a space between the mold cover plate and the face plate of the injection unit of the machine. A common carrier unit is provided for shifting the article ejection and sprue extraction units jointly into and out of the said spaces. In a preferred construction, the article ejection unit includes a plurality of ejector pins for the mold cavities, and means responsive to the arrival of the ejection unit at the end of its in-stroke for causing the ejector pins to penetrate the cavities from one face of the cavity plate. A trough-shaped guide unit movable with the ejection unit but into juxtaposition to the other face of the cavity plate is also provided, to define a guide chute for the ejected articles. The sprue extraction unit includes a rotatably driven roller which during its in-stroke is in rubbing or wiping contact with the outside face of the mold cover plate for pulling the cured sprues therefrom. This abstract is not to be taken either as a complete exposition or as a limitation of the present invention.
[US4124352A]
Patent IE-881895-L (IE)
Title: Double-stranded rna correction of aberrant metabolic¹pathways associated with uncontrolled tumor cell and virus¹growth cycles
IPC: C07H21/00
Filed: 1988-06-22
Abstract: A diagnostic method for assessing defects in RNase L comprising measuring activated RNase L in a cytoplasmic extract of a patient's mononuclear cells, preferably by measuring the mononuclear cells' ability to generate specific cleavage products when incubated with 28S and 18S RNA or the mononuclear cells' ability to generate cleavage products over a predetermined period of time.