baber/WOPTO huggingface dataset:
Patent AU-2014287880-A1 (AU)
Title: Bioactive polypeptide monomer-immunoglobulin Fc fragment conjugate having decreased receptor-mediated clearance, and method for preparing same
Inventor: PARK SUNG HEE
IPC: A61K39/395
Filed: 2014-07-14
Abstract: The present invention relates to: a composition containing a conjugate having a bioactive polypeptide linked to an immunoglobulin Fc fragment, wherein the composition is a sustained pharmaceutical composition containing a monomer conjugate having one molecule of bioactive polypeptide linked to one immunoglobulin Fc fragment, and optionally a multimer conjugate having two or more molecules of identical bioactive polypeptide linked to one immunoglobulin Fc fragment, wherein the molar ratio of the monomer conjugate to the multimer conjugate in the composition is 19 or greater; a bioactive polypeptide monomer-immunoglobulin Fc fragment conjugate in which a bioactive polypeptide monomer and an immunoglobulin Fc fragment are linked via a non-peptide linker, wherein the bioactive polypeptide is linked, in a monomer form, to one immunoglobulin Fc fragment via the non-peptide linker, and demonstrates a lower receptor-mediated internalization or receptor-mediated clearance, compared to a dimer conjugate having two molecules of bioactive polypeptide linked to one immunoglobulin Fc fragment via a non-peptide polymer, or a bioactive polypeptide-immunoglobulin Fc fragment inframe conjugate; and a method for preparing the sustained pharmaceutical composition.
Patent AU-2014302306-A1 (AU)
Title: Flow sensor
Inventor: DESILVA ADRIAN D
IPC: G01F1/34
Filed: 2014-06-26
Abstract: A flow sensor comprises a flow restriction disposed within a passage such that a fluid passing through the passage must pass through the flow restriction. The flow sensor also has an upstream pressure sensor coupled to the passage at a point upstream of the flow restriction and configured to measure and provide an upstream pressure of the fluid within the passage, a downstream pressure sensor coupled to the passage at a point downstream of the flow restriction and configured to measure and provide a downstream pressure of the fluid within the passage, and a temperature sensor coupled to the passage and configured to measure and provide a temperature of the fluid within the passage. The flow sensor also includes a flow sensor processor coupled to the upstream and downstream pressure sensors and the temperature sensor and configured to accept measurements therefrom and calculate a compensated flow rate based at least in part on the measured pressures and temperature.
Patent AU-2014346457-A1 (AU)
Title: Systemic delivery of myostatin short interfering nucleic acids (siNA) conjugated to a lipophilic moiety
Inventor: SEPP-LORENZINO LAURA
IPC: C12N15/113
Filed: 2014-11-10
Abstract: The present invention provides methods comprising the in vivo delivery of small nucleic acid molecules capable of mediating RNA interference and reducing the expression of myostatin, wherein the small nucleic acid molecules are introduced to a subject by systemic administration. Specifically, the invention relates to methods comprising the in vivo delivery of short interfering nucleic acid (siNA) molecules that target a myostatin gene expressed by a subject, wherein the siNA molecule is conjugated to a lipophilic moiety, such as cholesterol. The myostatin siNA conjugates that are delivered as per the methods disclosed are useful to modulate the in vivo expression of myostatin, increase muscle mass and/or enhance muscle performance. Use of the disclosed methods is further indicated for treating musculoskeletal diseases or disorders and/or diseases or disorders that result in conditions in which muscle is adversely affected.
Patent AU-2014348748-A1 (AU)
Title: Shopping trip planner
Inventor: MACLAURIN MATTHEW BRET
IPC: G06Q30/00
Filed: 2014-11-12
Abstract: A system and method of an intelligent shopping infrastructure is provided. A data storage of current inventory from a plurality of merchants is maintained. User preferences that indicate an item affinity of a user are retrieved. Furthermore, a location of the user is detected. Using the detected location, available inventory, and item affinity, an available item from the current inventory of a merchant located within a predetermined distance to the location of the user that match the item affinity of the user is identified. The available item is presented on a user interface of a client device of the user.
Patent AU-2014398345-A1 (AU)
Title: Method for producing synthetic pentapeptide
Inventor: MURAYAMA ASAMI
IPC: C07K5/107
Filed: 2014-12-19
Abstract: Provided are: a method for industrially advantageously producing a high-purity pentapeptide; and a production intermediate thereof. A compound represented by formula (1) or a salt thereof. (In the formula, R
Patent AU-2015200385-A1 (AU)
Title: Method and system for extrusion and intrusion detection in a cloud computing environment using network communications devices
Inventor: CABRERA LUIS FELIPE
IPC: H04L29/06
Filed: 2015-01-28
Abstract: An analysis trigger monitoring system is provided in a network communications device associated with a cloud computing environment. One or more analysis trigger parameters are defined and analysis trigger data representing the analysis trigger parameters is generated. The analysis trigger data is then provided to the analysis trigger monitoring system and the analysis trigger monitoring system is used to monitor at least a portion of the message traffic sent to, or sent from, virtual assets in the cloud computing environment and relayed by the network communications device through a network communication channel to detect any message including one or more of the one or more analysis trigger parameters. A copy of at least a portion of any detected message including one or more of the one or more analysis trigger parameters is then transferred to one or more analysis systems for further analysis using a second communication channel that is separate from the network communication channel.
Patent AU-2015200789-A1 (AU)
Title: Vessel for microwave heating and cooking
Inventor: MAN KAI TANG MAGGIE
IPC: B65D43/02
Filed: 2015-02-17
Abstract: A container assembly for use in microwave cooking and/or heating includes a container (10) having a base (20) and a peripheral side wall (18) which extends in a direction upwardly from the base (20), forming an enclosure which is open at that end which is spaced apart from the base (20), and a lid (16) for the open end of the container, that lid (16) including an adjustable closure means to allow for controlled egress of fluid, for example steam and/or heated air, from the container assembly, the base further including a protuberance (28) which extends upwardly into the enclosure and means for spacing the base from a surface on which the container assembly is disposed. si 22
Patent AU-2015201341-A1 (AU)
Title: Compositions comprising enzyme-cleavable ketone-modified opioid prodrugs and optional inhibitors thereof
Inventor: JENKINS THOMAS
IPC: A61K31/485
Filed: 2015-03-13
Abstract: COMPOSITIONS COMPRISING ENZYME-CLEAVABLE KETONE-MODIFIED OPIOID PRODRUGS AND OPTIONAL INHIBITORS THEREOF Abstract A method of providing a patient with controlled release of ketone-containing opioid using a prodrug capable, upon enzymatic activation and intramolecular cyclization, of releasing the ketone-containing opioid is disclosed. The disclosure also provides such prodrug compounds and pharmaceutical compositions comprising such compounds. Such pharmaceutical compositions can optionally include an enzyme inhibitor that interacts with the enzyme(s) to mediate the enzymatically-controlled release of the ketone-containing opioid from the prodrug so as to modify enzymatic cleavage of the prodrug. Also included are methods to use such compounds and pharmaceutical compositions.
Patent AU-2015203111-A1 (AU)
Title: Use of microvesicles in diagnosis, prognosis and treatment of medical diseases and conditions
Inventor: BREAKEFIELD XANDRA O
IPC: C12Q1/68
Filed: 2015-06-11
Abstract: The presently disclosed subject matter is directed to methods of aiding diagnosis, prognosis, monitoring and evaluation of a disease or other medical condition in a' subject by detecting a biomarker in microvesicles isolated from a biological, sample from the subject. Moreover, disclosed subject matter is directed to methods of diagnosis, monitoring a disease by determining the concentration of microvesicles within a biological sample; methods of delivering a nucleic acid or protein to a target all by administering microvesicles that contain said nucleic acid or protein; methods for performing a body fluid transfusion by introducing a microvesicle-free or microvesicle enriched fluid fraction into a patient.
Patent AU-2015206540-A1 (AU)
Title: Depletion block to block nerve communication
Inventor: FRANKE MANFRED
IPC: A61N1/36
Filed: 2015-01-14
Abstract: An example of a system may include a depletion block neural stimulator and a depletion block controller. The depletion block neural stimulator may be configured to deliver a depletion block stimulation to a nerve. The depletion block stimulation may include a series of pulses at a pulse frequency within a range between about 100 Hz to about 1000 Hz. The depletion block controller may be configured to communicate with the depletion block neural stimulator and control the depletion block stimulation. The depletion block controller may be configured to receive a start depletion block signal and respond to the received start depletion block signal by initiating the delivery of the depletion block stimulation to the nerve, and the depletion block controller may be configured to receive a stop depletion block signal and respond to the received stop depletion block signal by terminating the delivery of the depletion block stimulation to the nerve.
Patent AU-2015217149-A1 (AU)
Title: Novel full spectrum anti-dengue antibody
Inventor: SASISEKHARAN RAM
IPC: C12P21/08
Filed: 2015-02-11
Abstract: The present invention provides, among other things, antibody agents (e.g., antibodies, and/or antigen-binding fragments thereof) that bind to DV epitopes, as well as compositions containing them and methods of designing, providing, formulating, using, identifying and/or characterizing them. In some embodiments, provided antibody agents show significant binding to a plurality of DV serotypes. In some embodiments, provided antibody agents show significant binding to all four DV serotypes. Such antibody agents are useful, for example, in the prophylaxis, treatment, diagnosis, and/or study of DV.
Patent AU-2015228751-A1 (AU)
Title: TCR libraries
Inventor: JAKOBSEN BENT KARSTEN
IPC: C07K14/725
Filed: 2015-03-13
Abstract: The present invention relates to a library of particles, the library displaying a plurality of different T cell receptors (TCRs), wherein the plurality of TCRs consists essentially of TCRs comprising an alpha chain variable domain from a natural repertoire and a beta chain variable domain from a natural repertoire, wherein the alpha chain variable10 domain comprises a TRAV12-2 or a TRAV21 gene product and the beta chain variable domain comprises a TRBV6 gene product.
Patent AU-2015231943-A1 (AU)
Title: Optical data transfer utilizing lens isolation
Inventor: HILARIO ALVIN J
IPC: H04B10/40
Filed: 2015-01-27
Abstract: A first electronic device optically communicates with a second electronic device. Each of the devices includes one or more optical transmitters, one or more optical receivers, and one or more lenses where each of the lenses includes at least a first and a second optical path that are optically isolated from each other. When the first electronic device transmits data to the second electronic device, an optical transmitter of the first electronic device transmits to an optical receiver of the second electronic device via the first optical paths of the lenses of the first and second electronic devices. Similarly, when the first electronic device receives data from the second electronic device, an optical receiver of the first electronic device receives from an optical transmitter of the second electronic device via the second optical paths of the lenses of the first and second electronic devices.
Patent AU-2015247592-A1 (AU)
Title: Corneal inlay delivery devices and methods
Inventor: ESGUERRA NICOLAS
IPC: A61F2/14
Filed: 2015-04-16
Abstract: Corneal implant inserters and methods of use. The inserters are adapted such that they can be used to deliver corneal inlays into corneal pockets.
Patent AU-2015275869-A1 (AU)
Title: Improved weld procedures and weld procedure approval test
Inventor: COOPER NORMAN
IPC: B23K103/04
Filed: 2015-06-16
Abstract: A test method is provided to reproducibly test under matched HY100 welds to robustly establish the production parameters for the welding process. The test method comprises forming a 'U' shaped groove (120) in a plate to which steel members (112) are welded on the reverse side. The steel members (112) comprise transverse members that extend across the weld. The transverse members (112) are arranged at a density of at least four members for each 0.5m length of weld and preferably five transverse members. The steel members (112) further comprise longitudinal stiffeners that extend parallel to the weld. The longitudinal stiffeners are arranged at a density of two stiffeners per 0.4m width of the plate. The high density of stiffeners has provided a reproducible and reliable weld test method that is capable of being used to establish and approve production parameters for the welding process of under matched HY100 welds.
Patent AU-2015282352-A1 (AU)
Title: A method and apparatus for signaling to a mobile device which set of training sequence codes to use for a communication link
Inventor: DHANDA MUNGAL SINGH
IPC: H04L27/18
Filed: 2015-12-24
Abstract: A method of receiving signal training sequence set information by a remote station is disclosed. In an embodiment the method comprises sending signaling to a base station indicating if a new set of training sequences is supported, each training sequence of the new set being different than training sequences of a legacy set of training sequences; and receiving a channel description information element identifier from the base station, wherein the channel description information element identifier indicates whether to use the new set or the legacy set of training sequences for a communication channel being established. 1701 Start 1710 Receive signaling from a remote station indicating if a new set of training sequences is supported Use a channel description to signal the training sequence to be 1720 used by the remote station for a communication channel being established, where the channel description comprises a channel type field and a TDMA offset field.
Patent AU-2015282903-A1 (AU)
Title: A hydrogen-redox flow battery assembly
Inventor: KOUT WIEBRAND
IPC: H01M8/20
Filed: 2015-07-02
Abstract: A hydrogen-redox flow battery assembly (1) comprising: - one or more battery cells (10), each battery cell (10) comprising: - a hydrogen chamber (100); - an electrolyte chamber (110); - a membrane electrode assembly (120) positioned between said hydrogen chamber (100) and said electrolyte chamber (110); - a hydrogen reservoir (30); and - an electrolyte reservoir (31); CHARACTERIZED IN THAT: - said hydrogen-redox flow battery assembly (1) is further configured to allow an uncontrolled pressure difference between the pressure in said hydrogen chamber (100) and the pressure in said electrolyte chamber (110),wherein said pressure difference is determined by a diffusion of protons (200) through said membrane electrode assembly (120) during a charge (2) and/or a discharge (3) operation; and - said one or more battery cells (10) of said hydrogen-redox flow battery assembly (1) is/are completely positioned in said hydrogen reservoir (30).
Patent AU-2015289923-A1 (AU)
Title: Multilevel video compression, decompression, and display for 4K and 8K applications
Inventor: DECEGAMA ANGEL
IPC: H04N7/12
Filed: 2015-07-13
Abstract: Embodiments of this invention include computer-implemented methods for use of Haar wavelet transforms (HWT) to pre-process video frames that can then be compressed using a codec to produce a compressed video frame. A compressed video frame can then be transmitted, decompressed, post-processed and displayed in their original size and quality, thereby producing real-time high-quality reproduction of video sequences. Devices can implement methods of this invention and include mainframe computers, desktop computers, personal computers, laptop computers, tablet computers, wireless computers, television sets, set top boxes, cellular telephones, and computer readable media. Computer implemented steps can be easily and efficiently implemented in multicore parallel hardware architectures.
Patent AU-2015292239-A1 (AU)
Title: Combination glove for detecting breach of hydrophilic fluid
Inventor: ENG AIK HWEE
IPC: A61B42/00
Filed: 2015-07-22
Abstract: Provided for example is a combination glove comprising: (a) an top elastomer layer with an inner surface, the top elastomer layer being translucent or transparent; (b) an bottom elastomer layer with an outer surface, the bottom elastomer layer being darker than the top elastomer layer; and (c) a space or seam between the layers, wherein to either the inner-top or the outer-bottom surface has been adhered a hydrophilicity promoting composition of (i) a polyvinyl alcohol or (ii) an alkyl-aryl compound or a siloxane compound having a pendent one to two oxy-polymers, or (iii) a quaternary amine including an alkyl of C8 to C24, wherein the oxy-polymer is (1 ) a poly-oxyalkylene polymer that is predominantly oxyethylene or (2) a polyvinyl alcohol, wherein the hydrophilicity promoting composition enhances the spreading in the space or seam of any of the hydrophilic or aqueous fluid that breaches the top or bottom elastomer layer.
Patent AU-2015298766-A1 (AU)
Title: One measurement gap in asynchronous dual connectivity
Inventor: HUANG RUI
IPC: H04W24/00
Filed: 2015-05-27
Abstract: In an embodiment, an apparatus to be employed in a user equipment (UE) is described. The apparatus includes configuration circuitry operable to determine, based on one or more configuration information messages, a measurement gap for a master evolved Node B (MeNB) that is operable to provide a master cell group (MCG) that is asynchronous with a secondary cell group (SCG) of a secondary evolved Node B (SeNB), wherein subframe boundaries of the MCG are different from subframe boundaries of the SCG; and radio frequency (RF) control circuitry operable to cause RF circuitry to be tuned, at a beginning of the measurement gap based on a subframe boundary of the MCG, to start inter-frequency measurements, wherein the RF circuitry is to be used to transmit or receive data in a serving cell of the MCG and in a serving cell of the SCG. Other embodiments are also described and claimed.
Patent AU-2015334596-A1 (AU)
Title: Pulling systems and methods
Inventor: ANDREWS MICHAEL
IPC: F16C3/02
Filed: 2015-10-23
Abstract: Described herein is a mechanical pulling device having in one example a main shaft with an upper body longitudinally positionable along the main shaft. An upper pivot is provided on each transverse end of the upper body for pivotable attachment of a plurality of upper arms. A lower body is provided; longitudinally positionable along the main shaft with a lower body pivot on opposing lateral sides of the main shaft; the lower body positionable independent of the upper body; a plurality of upper arms each having a first end pivotably attached to the upper body via the upper pivots; each upper arm having a second end with an outer pivot; a jaw arm having a first end pivotably attached to the second end of the upper arm via the outer pivots; each jaw arm having a medial portion pivotably attached to opposing lateral sides of the lower body via the lower body pivot; each jaw arm having a second end opposed to the first end and having a grasping jaw in a plane passing through the axis of the main shaft; and each of the upper body pivots, lower body pivots, and outer pivots having parallel axes of rotation.
Patent AU-2015335023-A1 (AU)
Title: Pump dispensers
Inventor: KNIGHT SIMON CHRISTOPHER
IPC: B05B15/00
Filed: 2015-10-20
Abstract: A dispenser for dispensing a flowable product from a container has a pump module (2) mounted on the container (1) at an opening thereof. The pump module includes a pump body, which defines a pump chamber and a pump chamber inlet for product to flow from the container interior into the pump chamber. A pump actuator (4) is operable in a pumping stroke relative to the pump body to vary the volume of the pump chamber and dispense the product. The pump includes a movable body portion (3) which is operable in a displacement stroke into the container. The movable portion has a displacement body (34) with a product-engaging face directed onto an interior product space of the container upstream of the pump chamber inlet, to assist priming. Below this a disrupter member (6), a grid of narrow bars, projects to penetrate the product.
Patent AU-2016201571-A1 (AU)
Title: Pelvic floor treatments and related tools and implants
Inventor: ROCHELEAU GARY A
IPC: A61F2/00
Filed: 2016-03-10
Abstract: Abstract The present invention identifies pelvic implants, components of implants, related devices, systems and kits containing these, and methods of using these for treating pelvic conditions such as incontinence (various forms such as fecal incontinence, stress urinary incontinence, urge incontinence, mixed incontinence), vaginal prolapse (including various forms such as enterocele, cystocele, rectocele, apical or vault prolapse, uterine descent), conditions of the pelvic floor and result from weakness or trauma of pelvic floor muscles such as the levator or coccygeus muscle and other conditions caused by muscle and ligament weakness. In particular, the invention identifies a kit comprising a pelvic implant comprising a support portion piece; an extension portion piece; wherein the extension portion piece comprises a mesh portion and a non-mesh portion, and the support portion piece comprises an adjusting engagement capable of adjustably engaging the extension portion piece; a grommet management tool; and at least one grommet engaged with the grommet management tool.
Patent AU-2016202451-A1 (AU)
Title: A gutter system
Inventor: JANNEY IAN
IPC: E04D13/076
Filed: 2016-04-18
Abstract: A GUTTER SYSTEM Abstract A gutter system comprising an elongated hollow gutter formed by one or more shaped hollow gutters joined end to end; an elongated entry slot extending substantially along the elongated hollow gutter and sized to receive and to be mounted on the overhanging edge of a roof structure to allow rain runoff from the roof to enter the elongated hollow gutter through the elongated entry slot; an outlet in the elongated shaped hollow gutter for directing the rain runoff away from the roof, wherein the gutter system allows for ready sizing to match a roof size; and a mounting system for supporting the elongated hollow gutter on the edge of the roof structure. 1/lu mNNom Figure 2
Patent AU-2016203252-A1 (AU)
Title: Reinforcement member for handle of tool
Inventor: BOTHMANN RICHARD D
IPC: B25F5/02
Filed: 2016-05-18
Abstract: A tool, such as a pneumatic tool, having a first and second housing portions coupled together. The first housing portion including an upper portion adapted to receive power and transmission components and a handle portion including a recess adapted to receive a 5 trigger assembly. A reinforcement member is disposed in the recess with a first side facing in a first direction away from the recess and towards the second housing portion, and a protrusion extending from the first side in the first direction. The protrusion engages the second housing portion and strengthens the handle portion to allow the handle portion to withstand forces resulting from the tool being dropped on a hard surface. 7760448 1 (GHMatters) P103003.AU 112-- 114 110-