baber/WOPTO huggingface dataset:
Patent NZ-548596-A (NZ)
Title: Novel inhibitors of glutaminyl cyclase and their use in treating neuronal diseases
Inventor: SCHILLING STEPHAN
IPC: C07D235/06
Filed: 2005-02-04
Abstract: Disclosed is a compound of formula 1, where A is an unbranched C3 alkyl chain, B is either of formula (VI) or (VIII), X is S or N-CN, Y is S, or a compound of formula (1a), (1b), (1g), or (X), or a stereoisomer, polymorph, or pharmaceutically acceptable salt thereof. Also disclosed is the use of the compound for treating neuronal disorders, such as Alzheimer's disease, Down Syndrome, Parkinson disease, Chorea Huntington, pathogenic psychotic conditions, schizophrenia, impaired food intake, sleep-wakefulness, impaired homeostatic regulation of energy metabolism, impaired autonomic function, impaired hormonal balance, impaired regulation, body fluids, hypertension, fever, sleep dysregulation, anorexia, anxiety related disorders including depression, seizures including epilepsy, drug withdrawal and alcoholism, neurodegenerative disorders including cognitive dysfunction and dementia.
Patent NZ-551447-A (NZ)
Title: Methods for dynamic vector assembly of DNA cloning vector plasmids
Inventor: REED THOMAS D
IPC: C12N15/85
Filed: 2005-05-18
Abstract: Disclosed is a method of constructing a transgene or a method for simultaneously synthesizing an array of transgenes the method comprising the steps of: a. providing a cloning vector plasmid with a backbone comprising first and second docking points capable of accepting a sequential arrangement of inserts, each docking point being fixed within the backbone and comprising at least one non-variable rare endonuclease site for an endonuclease enzyme; b. providing at least a first insert and a second insert to be included in the transgene, each insert comprising a 5' end, a nucleotide sequence of interest and a 3' end, wherein the 5' end of the first insert is compatible to the 3' end of the cleaved first docking point, and the 3' end of the second insert is compatible to the 5' end of the cleaved second docking point; and c. transferring both the first insert and the second insert into the backbone in a single reaction. Further discloses is an alternative method of constructing a transgene or a method for simultaneously synthesizing an array of transgenes the method comprising the steps of: a. providing a cloning vector plasmid comprising first and second docking points; b. introducing first nucleotide sequences to be included in the transgene into a first shuttle vector; c. introducing second nucleotide sequences to be included in the transgene into a second shuttle vector; and d. transferring simultaneously the first nucleotide sequences and the second nucleotide sequences from the shuttle vectors to the cloning vector plasmid, between the first and second docking points, wherein the 5' end of the first insert is compatible to the 3' end of the first docking point, and the 3' end of the second insert is compatible to the 5' end of the second docking point.
Patent NZ-560456-A (NZ)
Title: Purification technique
Inventor: SAUL DAVID JAMES
Filed: 2005-06-17
Abstract: Disclosed is a method for the removal of at least one contaminant from a composition, wherein said contaminant is a substrate of one or more mesophilic enzyme, said method comprising the steps of: adding to the composition said one or more mesophilic enzyme and at least one thermophilic protease; and maintaining said composition at a first temperature or temperature range at which said one or more mesophilic enzyme has enzymatic activity, but at which said at least one thermophilic protease has minimal or no proteolytic activity; and maintaining said composition at a second temperature or temperature range at which said at least one thermophilic protease has proteolytic activity; and maintaining said composition; wherein said one or more mesophilic enzyme does not exhibit activity effective to remove cell walls.
Patent NZ-560608-A (NZ)
Title: Fireproofing agent comprising at least one carbon donor comprising an alkali metal of a polyhydric acid containing at least seven carbon atoms and at least one phosphorus containing acid comprising at least one amino group
Inventor: PETERMULLER MANFRED
IPC: B27K3/52
Filed: 2006-01-20
Abstract: Disclosed is a flame retardant for reducing the risk of fire posed by an ignitable substance, where the flame retardant comprises at least one carbon donor and at least one phosphorus containing acid; wherein the carbon donor comprises an alkali metal compound of a polyhydric alcohol comprising an alkane skeleton having at least seven carbon atoms; the phosphorus containing acid comprises an acid selected from the group phosphoric acid, phosphonic acid and phosphorous acid and further comprises at least one amino acid.
Patent NZ-563260-A (NZ)
Title: Method of creating a financial instrument
Inventor: MOORE HOWARD BRYCE
IPC: G06Q99/00
Filed: 2007-11-07
Abstract: A central processing station for creating a financial instrument is disclosed. The central processing station is configured to a) select a real biological asset; b) assign one or more biological growth models to that real biological asset; c) determine a current value for the real biological asset; d) issue, based upon said current value one or more redeemable certificates associated with the real biological asset; and e) determine at any point in the future new current values of the certificates using the growth model. The central processing station is configured to a) select a virtual biological asset whose key characteristics are based upon those that would be present in an equivalent real biological asset; b) assign one or more biological growth models that would apply to the equivalent real biological asset to the virtual biological asset; c) determine a current value for the virtual biological asset using the growth model; d) issue, based upon said current value, one or more redeemable certificates associated with said virtual biological assets; and determine at any point in the future new current values of said certificates using the growth model.
Patent NZ-564647-A (NZ)
Title: Detecting an acoustic signal at two points to determine velocity of signal and thickness of pipe
Inventor: HUNAIDI OSAMA
IPC: G01M3/02
Filed: 2006-06-19
Abstract: Disclosed is a method of performing a non-destructive condition assessment of a pipe carrying a fluid. In the method, an actual value representative of the propagation velocity of an acoustic disturbance propagating between two longitudinally separated points on the pipe is determined. A corresponding predicted value for the propagation velocity is computed as a function of at least one wall thickness parameter of the pipe by using a theoretical model for the propagation of acoustic waves in the pipe. The model assumes the pipe has a finite wall thickness with a predetermined circumferential thickness profile. The wall thickness parameter is then computed by matching the actual value with the predicted value.
Patent NZ-566917-A (NZ)
Title: An apparatus for preventing deep vein thrombosis with sequenced compression of limb
Inventor: MEYER WALTER
IPC: A61H23/02
Filed: 2006-08-11
Abstract: An apparatus (40) for enhancing blood flow through a limb of a subject includes a compression sleeve (41) extendable around the subject's limb and having a plurality of compressors (43-48) situated next to one another along the sleeve (41). In use, the compressors (43-48) compress the limb in sequence to move blood within the limb from one end of the sleeve (41) to the other. In particular, as a said compressor (43-48) begins to compress the limb, the compressor (43-48) preceding it in sequence already compresses the limb, and the next preceding compressor (43-48) in sequence ceases to compress the limb.
Patent NZ-568152-A (NZ)
Title: A lock with a hold back function
Inventor: NEWMAN DONALD JOHN
Filed: 2006-11-16
Abstract: A lock with a mechanism to enable the lock tongue or latch tongue to be held back is disclosed. The lock has a body (10), a lock tongue (11) which can move between a locking position and a free (unlocking) position, and a hold back member (12) which can move between (a) a hold back position where the hold back member can hold the lock tongue in the free position, and (b) a release position where the lock tongue can move to the locking position. The hold back member is operable from (b) to (a) from externally of the lock, and the lock tongue is able to move from the locking position to the free position when the hold back member is in position (a). A rearwardly extending portion of the tongue has a recess (15) adapted to engage with part of the hold back member to prevent the tongue from moving to the locking position.
Patent NZ-573837-A (NZ)
Title: IL-17 A/F heterologous polypeptides and therapeutic uses thereof
Inventor: GURNEY AUSTIN
IPC: A61K38/20
Filed: 2004-06-02
Abstract: A bispecific antibody comprising a first antigen binding site that binds to IL-I7A and asecond antigen binding site that binds to IL-I7F, wherein (1) the first antigen binding site comprises a first heavy chain variable domain, and (2) the second antigen binding site comprises a second heavy chain variable domain or a functional fragment of the bispecific antibody. (62) Divided Out of 544317
Patent NZ-577677-A (NZ)
Title: Use of a transaction number generator that incorporates account number
Inventor: BELAMANT SERGE CHRISTIAN PIERRE
IPC: G06Q20/40
Filed: 2007-11-16
Abstract: Disclosed is a financial transaction number generator (10) for generating a unique transaction number. The generator includes an electronic processing device, a memory unit (18), an input device (16) and a display (14). The input device (16) is operable by a transactor to input a request for a simulated primary account number. This simulated account number can then be displayed on the display (16). The financial transaction number generator is arranged to generate a unique transaction number that simulates a conventional credit or debit card primary number and incorporates an account number of the transactor. The account number can be extracted from the transaction number by a designated transaction processing facility (30) of a financial institution (26).
Patent NZ-584005-A (NZ)
Title: Galenical formulations of aliskiren
Inventor: BIANCHI JEAN-CLAUDE
IPC: A61K9/28
Filed: 2008-09-24
Abstract: Disclosed is a roller compacted solid oral dosage form comprising a therapeutically effective amount of Aliskiren or a pharmaceutically acceptable salt thereof, wherein active ingredient is present in an amount of more than 38% by weight based on the total weight of the oral dosage form and wherein the dosage form further comprises calcium hydrogen phosphate as a filler. Also disclosed is the use of the solid oral dosage form for the manufacture of a medicament for the treatment of hypertension, congestive heart failure, angina, myocardial infarction, atherosclerosis, diabetic nephropathy, diabetic cardiac myopathy, renal insufficiency, peripheral vascular disease, left ventricular hypertrophy, cognitive dysfunction, stroke, headache or chronic heart failure.
Patent NZ-586577-A (NZ)
Title: Mineral wool sizing composition comprising a monosaccharide and/or a polysaccharide and an organic polycarboxylic acid, and insulating products obtained
Inventor: JAFFRENNOU BORIS
IPC: C03C25/146
Filed: 2008-12-04
Abstract: Disclosed is a sizing composition for insulating products based on mineral wool, which comprises: - at least one monosaccharide and/or at least one polysaccharide, - at least one non-polymeric organic polycarboxylic acid having a molar mass of less than or equal to 1000, and - a catalyst chosen from Lewis acids and bases, phosphorus comprising compounds and compounds comprising fluorine and boron. Also disclosed is an insulating product such as a panel or veil for acoustic and/or thermal insulation based on glass or rock and the process for making the product.
Patent NZ-591738-A (NZ)
Title: Non-typhoidal salmonella vaccines comprising a polypeptide which is an outer membrane protein d of non typoidal salmonella
Inventor: CUNNINGHAM ADAM
IPC: A61K39/02
Filed: 2009-09-09
Abstract: NZ 591738 Disclosed is the use of an immunogenic polypeptide which comprises: a polypeptide which is an Outer Membrane Protein (OmpD) or an immunogenic fragment thereof having the ability to generate an antibody response against Non-Typhoidal Salmonella (NTS); or a variant of a polypeptide as defined in (i) which has said ability, in the manufacture of a vaccine composition for the treatment or prevention of infection and/or disease by OmpD-containing Salmonella.
Patent NZ-593895-A (NZ)
Title: Auxin herbicide composition
Inventor: SAYER CHAD RICHARD ORD
IPC: A01N37/40
Filed: 2009-12-23
Abstract: ABSTRACT - 593895 The disclosure relates to a stable aqueous liquid auxin herbicide composition comprising a solution of at least one of 2,4-dichlorophenoxyacetic acid (2,4,D) and 3,6-dichloro-o-anisic acid (dicamba) in the form of the monomethylamine salt and at least one of 2,4-D and dicamba in the form of the dimethylamine salt wherein the molar ratio of monomethylamine to dimethylamine is in the range of from 1:20 to 4:6 and wherein the concentration of at least one of 2,4-D and dicamba is at least 500 g/L based on herbicidal acid equivalent. The combination of the monomethylamine (MMA) and dimethylamine (OMA) salts of at least one of 2,4-D and dicamba in said molar ratio of monomethylamine to dimethylamine significantly improves the solution stability of said auxins allowing significantly higher loadings to be formulated.
Patent NZ-605615-A (NZ)
Title: Wheelchair
Inventor: TUCKOWSKI THOMAS
IPC: A61G5/10
Filed: 2011-06-24
Abstract: 605615 The present disclosure relates generally to conveyances and, more particularly, to wheelchairs. In one embodiment, a wheelchair includes a seat assembly coupled to a chassis. The chassis includes a frame having a rear wheel support member, one or more front wheel support members extending in a forward direction from the rear wheel support member, and a seat support member. The rear wheel support member comprises a central portion and left and right portions extending downward from the central portion. The wheelchair also includes one or more drive wheels for propulsion of the wheelchair, a set of front wheels for supporting the wheelchair, and a shrouding system for at least partially covering the frame and other components of the wheelchair.
Patent NZ-608469-A (NZ)
Title: Light assembly for domestic and industrial environments
Inventor: CALABRO DAVID
IPC: F21V7/00
Filed: 2010-03-19
Abstract: Disclosed is a light assembly for use in domestic and industrial environments, providing improved area illumination through a lighting assembly which includes an LED and diffuser or reflector and which and which reduces or eliminates unwanted reflected light. The assembly comprises a parabolic housing including an outer surface and an inner surface both terminating at an open first end of the housing and at an opposite closed second end. The housing defines an internal space which receives and retains at or near the second end, a mounting surface which receives and retains at least one light emitting diode (LED) mounted in the internal space. The housing further comprises on the inner surface a light reflective surface which receives and reflects light emitting from the LED’s and which is arranged to reflect at least the majority of all available light emitted from the at least one LED. The light reflective surface is arranged so that the angle between the reflective surface and light rays emitted from the LED’s, optimizes reflection of that light so that most or all light of available light for a given power rating emitted from the at least one LED is reflected. The light reflective surface includes a plurality of facets oriented to capture and reflect light emitted from the at least one LED to an illumination zone; wherein each facet has a first curved portion which receives light from a light source and a second curved portion which reflects light received at the first curved portion. There are facets at the second end located near the light source and facets at the first end located at a maximum distance from the light source. The facets are oriented relative to the direction of light emitting from an LED to enable formation of a low glare angle.
Patent NZ-616268-A (NZ)
Title: Process for preparing vaccine composition
Inventor: SKINNER MURRAY
IPC: A61K39/00
Filed: 2012-04-20
Abstract: Discloses a method of preparing a composition comprising one or more antigens adsorbed to an amino acid wherein said method comprises: (i) mixing a solution of one or more antigens with a solution of the amino acid in an aqueous acid whilst neutralising the mixture of solutions, thereby forming an adsorbate comprising the one or more antigens and the amino acid; (ii) separating the adsorbate into a buffer by cross-flow filtration thereby forming said composition; and (iii) recovering said composition; wherein steps (i) to (iii) are performed in a sterile environment and within a closed system.
Patent NZ-623771-A (NZ)
Title: Truss system
Inventor: BURGESS REX KELVIN
IPC: E04D3/06
Filed: 2012-08-15
Abstract: A truss system for a roof or façade of a building is disclosed. Each truss segment comprises first and second elongate elements (14, 16). The elongate elements (14, 16) are interconnected at intervals by a series of fish-plate assemblies which have first and second flanged plates (18a, 18b) arranged back to back and retained within channels (20) in the elongate elements (14, 16).
Patent NZ-628823-A (NZ)
Title: Acid etch resistance for calcareous substrates
Inventor: RAGHAVANPILLAI ANILKUMAR
IPC: C04B41/48
Filed: 2013-03-15
Abstract: Disclosed herein is a method to provide acid etch resistance, water and oil repellence, and stain resistance to a calcareous substrate by treating with an aqueous dispersion of a copolymer of formula I prepared from fluorinated methacrylate, short chain branched (meth)acrylate, and (meth)acrylic acid or a salt thereof. Also disclosed are substrates treated by the method.
Patent NZ-629630-A (NZ)
Title: Substituted heterocyclic acetamides as kappa opioid receptor (kor) agonists
Inventor: SASMAL PRADIP KUMAR
IPC: C07D417/00
Filed: 2013-03-05
Abstract: The present disclosure relates to a series of substituted compounds having the general formula (I), including their stereoisomers and/or their pharmaceutically acceptable salts, wherein R1, R2, R3. R4, R5, and R6 are as defined herein. This disclosure also relates to methods of making these compounds including intermediates. The compounds of this disclosure are effective at the kappa (κ) opioid receptor (KOR) site. Therefore, the compounds of this disclosure are useful as pharmaceutical agents, especially in the treatment and/or prevention of a variety of central nervous system disorders (CNS), including but not limited to acute and chronic pain, and associated disorders, particularly functioning peripherally at the CNS. The compounds disclosed include: N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phenylethyl)-N-methyl-2-(2-oxoindolin-6-yl)acetamide; N-[(1S)-2-[(3S)-3-hydroxypyrrolidin-1-yl]-1-phenylethyl]-2-(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)acetamide; N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phenylethyl)-N-methyl-2-(3-oxo-3,4-dihydroquinoxalin-6-yl)acetamide and; 2-(1,1-dioxido-3-oxo-3,4-dihydro-2H-benzo[b][1,4]thiazin-6-yl)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-(3-(trifluoromethoxy)phenyl)ethyl)-N-methylacetamide.
Patent NZ-705372-A (NZ)
Title: Formulations pharmacokinetics of deuterated benzoquinoline inhibitors of vesicular monoamine transporter 2
Inventor: SOMMER ANDREAS
IPC: A61K31/4375
Filed: 2013-09-18
Abstract: The present invention relates to extended-release pharmaceutical compositions comprising about 5 to about 30 mg of d6-tetrabenazine and a sustained-release polymer which is a polyvinyl acetate-polyvinyl pyrrolidone mixture or a poly(ethylene oxide) polymer, and uses of such compositions as medicaments to inhibit vesicular monoamine transporter 2 (VMAT2) activity in a subject for the treatment of chronic hyperkinetic movement disorders.
Patent NZ-710705-A (NZ)
Title: Chitooligosaccharides and methods for use in enhancing plant growth
Inventor: SMITH R STEWART
IPC: C05G3/60
Filed: 2012-09-24
Abstract: Disclosed herein are method of enhancing plant growth, comprising treating a plant seed and/or the plant that germinates from the seed with an effective amount of at least one chitoogilosaccharide (CO) less than one month prior to planting the seed and the seed is not also treated with a lipo-chitooligosaccharide (LCO). The treatment results in increased plant yield measured in terms of bushels/acre, increased root number, increased root length, increased root mass, increased root volume and increased leaf area, compared to plants harvested from untreated seed.
Patent NZ-712068-A (NZ)
Title: Low eructation composition and methods for treating and/or preventing cardiovascular disease in a subject with fish allergy/hypersensitivity
Inventor: OSTERLOH IAN
IPC: A61P3/06
Filed: 2011-11-28
Abstract: Disclosed is the use of ethyl eicosapentaenoate in the preparation of a medicament for treating hypertriglyceridemia in a subject identified as having a fasting baseline triglyceride level of about 500 mg/dl to about 2000 mg/dl and as being allergic to fish or seafood, wherein said medicament contains substantially no docosahexaenoic acid (DHA) or derivative thereof, and less than about 1%, by weight, of proteins, if any, and wherein the medicament does not cause skin rash or wherein the subject experiences reduced incidence of skin rash compared to placebo or to an equivalent milligram dose of a commercially available prescription omega-3 fatty acid composition.
Patent NZ-721050-A (NZ)
Title: Method for dredging an underwater bottom in an area using a dredging device
Inventor: VERSTRAELEN LUK
IPC: E02F5/00
Filed: 2014-12-15
Abstract: The invention relates to a method for dredging an underwater bottom in an area using a dredging device. The method comprises the steps, taking place via a digital network under the control of a computer, of determining the present positions of the dredging device and of a source of contamination in the area; entering input data relating to the area into a hydrodynamic model of the area; determining with the hydrodynamic model the degree of contamination at positions in the area resulting from spread of the contamination from the source; comparing the degree of contamination at positions in the area to a threshold value for these positions; and optionally adapting the dredging if the degree of contamination exceeds the threshold value. Underwater bottom can be dredged using the invented method, wherein on the one hand the production is maximized and on the other the consequences for the natural environment are minimized.
Patent NZ-746168-A (NZ)
Title: Immunocompetent cell and expression vector expressing regulatory factors of immune function
Inventor: TAMADA KOJI
IPC: A61P35/00
Filed: 2017-03-15
Abstract: The present invention addresses the problem of providing: an immunocompetent cell in which regulatory factors of immune function from immunocompetent cells are expressed in the immunocompetent cell, and which combines proliferative capacity, viability, and a capacity for T-cell accumulation; and an immune function regulatory factor expression vector for preparing said immunocompetent cell.　An immunocompetent cell is prepared which expresses interleukin 7 (IL-7), CCL19, and a cell surface molecule for specifically recognizing cancer antigens. The cell surface molecule for specifically recognizing cancer antigens is preferably a T-cell receptor that specifically recognizes cancer antigens, and the immunocompetent cell is preferably a T-cell.