baber/WOPTO huggingface dataset:
Patent CA-3142899-A1 (CA)
Inventor: DAMLE NITIN KRISHNAJI
IPC: A61P25/16
Filed: 2020-06-09
Abstract: L'invention concerne un procédé de traitement ou de prévention de synucléinopathies chez un sujet humain, comprenant l'administration d'une quantité thérapeutiquement efficace d'un composé de formule 1 (formule 1) ou de ses sels pharmaceutiquement acceptables.
Patent CA-3144137-A1 (CA)
Title: Metal sealing ring and method of forming a metal-to-metal seal
Inventor: LANGTRY ANTHONY VIVIAN
IPC: F16J15/08
Filed: 2020-06-18
Abstract: A metal sealing ring (1) for forming a metal-to-metal seal between two opposing metal surfaces. The metal sealing ring (1) comprises a tubular metal body (3) and an inlet tube (7) extending from the body (3) for introducing an internal pressure into the body (3). The body is adapted to deform under the internal pressure against each of the opposing metal surfaces to form the seal (1).
Patent CA-3148273-A1 (CA)
Title: Compositions and methods utilizing a novel human foxo3 isoform
Inventor: ZHAO BAHONG
IPC: A61P19/10
Filed: 2020-08-14
Abstract: Provided herein is a method of suppressing osteoclast differentiation or function and/or bone resorption or destruction in a subject in need thereof and compositions therefore. In one embodiment, the method includes increasing the amount, expression, or activity of Foxo3 isoform 2 in the subject.
Patent CA-3149518-A1 (CA)
Inventor: APONTE-RIVERA JOSE
IPC: A01H1/02
Filed: 2022-02-18
Abstract: The present invention is directed in part to soybean variety CL1920562, CL1920645, CL1920541, CL1920755, CL1920650, CL1920544, CL1920822, CL1920804, CL1920763, and/or CL1920828 breeding and development. The present invention particularly relates to soybean variety CL1920562, CL1920645, CL1920541, CL1920755, CL1920650, CL1920544, CL1920822, CL1920804, CL1920763, and/or CL1920828 and its seed, cells, germplasm, plant parts, and progeny, and methods of using CL1920562, CL1920645, CL1920541, CL1920755, CL1920650, CL1920544, CL1920822, CL1920804, CL1920763, and/or CL1920828, e.g., in a breeding program.
Patent CA-3151689-A1 (CA)
Title: Insecticidal proteins
Inventor: REYNOLDS CLARENCE MICHAEL
IPC: A01N63/20
Filed: 2020-10-13
Abstract: Compositions and methods for controlling insect pests are disclosed. In particular, novel insecticidal proteins having toxicity to at least coleopteran insect pests are provided. Nucleic acid molecules encoding the novel insecticidal proteins are also provided. Methods of making the insecticidal proteins and methods of using the insecticidal proteins and nucleic acids encoding the insecticidal proteins of the disclosure, for example in transgenic plants to confer protection from insect damage, are also disclosed.
Patent CA-3153063-A1 (CA)
Title: Nouvelle methode
Inventor: HOLT MATTHEW
IPC: C12N15/86
Filed: 2020-09-07
Abstract: L'invention concerne une méthode d'expansion d'une population de cellules T régulatrices dans un tissu ou un organe d'un sujet, ladite méthode consistant à administrer un IL-2 et une fraction de ciblage spécifique dudit tissu ou organe, et ledit tissu ou organe étant le système nerveux central et/ou périphérique. L'invention concerne en outre des populations de cellules T régulatrices produites selon la méthode et la production in vivo de ladite population. L'invention concerne également une composition pharmaceutique comprenant de l'IL-2 et une fraction de ciblage telle que définie dans la description, ainsi qu'une méthode de traitement d'une maladie ou d'un trouble médié par une inflammation ou de réduction d'une inflammation, qui comprend les méthodes définies dans la description ou l'administration d'une composition pharmaceutique telle que définie dans la description.
Patent CA-3154868-A1 (CA)
Inventor: JAUVIN ETIENNE
IPC: A63F13/825
Filed: 2020-11-25
Abstract: A computer-implemented method, gaming device and computer-readable medium for an Augmented Reality (AR) application. The method includes maintaining an AR gaming environment during a gaming session. The method also includes receiving image data representing a real-world scene including one or more real-world objects. The method also includes detecting in the image data at least one real-world object from a set of detectable real-world objects. The method further includes upon detection of the at least one real-world object in the image data, generating at least one virtual character in the AR gaming environment, the at least one virtual character having an association with the at least one real-world object.
Patent CA-3155789-A1 (CA)
Inventor: DE COTE JOSE ANTONIO
IPC: A01P21/00
Filed: 2022-04-12
Abstract: The present disclosure rehts to foimuhtions including Trichoderma isolats, as well as methods thereof. In particular embodiments, the foimulaticn can include cne or more Trichoderma isolats, in which the foundation can include solid carnets and/or liquid caniers. Such foundations can be useful for treating or protcting plants, as well as countracting growth of pathogenic organisms in proximity to the plant
Patent CA-3156735-A1 (CA)
Title: Electrically activated polymer based power locking device for earth moving equipment
Inventor: SERRURIER DOUGLAS C
IPC: E05B47/06
Filed: 2020-10-09
Abstract: A power locking device (500, 500') has a body (502, 502') including a blind bore (510, 510') with an electroactive polymer (514, 514') disposed in the blind bore (510, 510'), and a sliding lock member (516, 516') that is disposed in the blind bore (510, 510') and that contacts the electroactive polymer (514, 514'). A current source (518) is in electrical communication with the electroactive polymer (514, 514').
Patent CA-3157247-A1 (CA)
Inventor: AN WEIWEI
IPC: B62B5/00
Filed: 2019-11-08
Abstract: Chariot à bras électrique, comprenant : un corps principal (1), un dispositif d'alimentation électrique (9) monté sur le corps principal (1), un dispositif de puissance et un dispositif de commande. Le dispositif d'alimentation électrique (9) et le dispositif de commande sont connectés séparément au dispositif de puissance.
Patent CA-3158252-A1 (CA)
Inventor: STAHL ULF
IPC: C07K14/33
Filed: 2020-12-19
Abstract: The present technology relates to commercial-scale methods for purifying botulinum toxin compositions obtained from cell cultures. Purification methods according to the present disclosure are based on a series of filtration and chromatographic separation steps that produce a high-purity botulinum toxin composition, which comprises botulinum toxin protein molecules (~150 kDa) in solution, which is free, essentially free, or substantially free of botulinum toxin complexes and animal products, and without precipitating or lyophilizing botulinum toxin protein molecules. The purification method according to the present disclosure uses no precipitation, lyophilization, or centrifugation steps, permitting production of highly pure, highly active, free botulinum toxin protein molecules (~150 kDa) in solution, without the need for reconstitution by the end user.
Patent CA-3158967-A1 (CA)
Title: A user generated virtual room-based user interface
Inventor: MADONNA ROBERT P
IPC: H04W4/33
Filed: 2015-02-12
Abstract: In one embodiment, a technique is utilized to generate a virtual-room of a virtual room-based user interface that controls one or more devices within a physical room of a structure. A user is prompted to select one or more services provided by the one or more devices within the physical room. A plurality of images of the physical room are obtained that each share substantially a same perspective. The plurality of images include an all-off image, in which all of the one or more of the services are in an inactive state, and one or more service-specific images, in which a single service is in an active state and any other services are in the inactive state. The plurality of images are aligned to create an aligned image stack. 1    One or more hit boxes are designated. The virtual room is generated based on the aligned image stack and the designated one or more hit boxes.
Patent CA-3159150-A1 (CA)
Inventor: BAKER TURNER S
IPC: A61F7/12
Filed: 2020-11-20
Abstract: A detachable cooling apparatus comprises: a distal running catheter forming a distal lumen that provides liquid as an input and a proximal running catheter forming a proximal lumen that receives the liquid as an output, where the proximal running catheter is connected to the distal running catheter. A focal hypothermia-inducing fluidics system comprises a thermal management and flow system (TMFS) that is operable to alter a liquid to a specific temperature and to regulate a flow rate, a closed-circuit flow system with a detachable cooling apparatus, a distal sensor array, a pump for moving the liquid through the TMFS, an inflow port that receives the liquid from the proximal running catheter, a plurality of capillary tubes that cool the liquid, and an outflow port that returns the liquid to the distal running catheter.
Patent CA-3159535-A1 (CA)
Inventor: ZURBRIGGEN ANDREAS
IPC: A61P31/04
Filed: 2020-11-30
Abstract: La présente invention concerne un procédé de purification de polysaccharides à partir d'un lysat de cellules, comprenant la purification partielle du lysat de cellules comprenant une impureté et un polysaccharide pour obtenir un lysat brut clarifié ; le mélange du lysat brut clarifié avec une solution de neutralisation comprenant un sel pour former un lysat neutralisé ; le mélange du lysat neutralisé avec une solution de précipitation comprenant du bromure de cétyltriméthylammonium pour former un premier surnageant et un premier précipité ; et la séparation du premier précipité du premier surnageant, le polysaccharide étant situé dans le premier surnageant. La présente invention concerne en outre un procédé de fabrication d'un vaccin à polysaccharide. L'invention concerne en outre des vaccins, des systèmes d'administration, des compositions et des polysaccharides fabriqués par les procédés selon l'invention.
Patent CA-3159681-A1 (CA)
Title: Systems and methods for providing pre-emptive intercept warnings for online privacy or security
Inventor: DAO TUAN
IPC: H04L9/40
Filed: 2020-11-25
Abstract: Systems and methods for providing pre-emptive intercept warning for online privacy or security are disclosed. In one embodiment, at a privacy security appliance comprising at least one computer processor, a method for may include: establishing a virtual private network (VPN) connection with a computer application executed by a client device; receiving, over the VPN connection, an internet protocol (e.g., HTTP or HTTPS) request for a website host; communicating the internet protocol request to the website host; receiving a response to the internet protocol request from the website host; inspecting the response for privacy or security issues with embedded links in the response; scoring the embedded links based on the inspection; generating a mock webpage based on the response comprising the scoring for the embedded links; and delivering the mock webpage with the scoring to the application over the VPN. The mock webpage may include links to the embedded links.
Patent CA-3160319-A1 (CA)
Title: Headgear with directional adjustment mechanism
Inventor: KAPELEVICH VITALY
IPC: A61M16/06
Filed: 2020-11-13
Abstract: This disclosure provides a directional adjustment unit for a headgear for a respiratory mask. The directional adjustment unit provides an increased resistance to extension of one or more straps of the headgear when the headgear is under tensile forces, as compared to a lower resistance to retraction of the one or more headgear straps. The directional adjustment unit comprises a movable frictional engagement member comprising an aperture, wherein the aperture is arranged to receive a filament of a strap of the headgear therethrough, wherein the frictional engagement member in a first configuration provides a disengaged or pre-activated configuration with respect to the filament, and in a second configuration provides an engaged configuration with respect to the filament. Features are provided which improve the operation of such a directional adjustment unit. These features include features to help resist bending of the filament inside the directional adjustment unit, features to vary frictional engagement between the frictional engagement member and the filament, and features to reduce sticking of the frictional engagement member in a given position.
Patent CA-3161297-A1 (CA)
Inventor: NARITA TAKASHI
IPC: E03C1/10
Filed: 2020-11-04
Abstract: A flow channel switching system (1, 1') comprising: a first on-off valve (10) which is disposed between a merging part (6) and a branching part (5) and in a raw water path (4); a second on-off valve (11) which is disposed in a raw-water outward path (7); and a sensor (13) for making a measurement of the condition of water flowing through the raw water path, wherein control is performed so as to open the second on-off valve and close the first on-off valve if a signal indicating that water is flowing in the raw water path is received from the sensor, then a signal indicating that no water is flowing in the raw water path is received, and then, within a predetermined period of time, a signal indicating that water is flowing again in the raw water path is received.
Patent CA-3162134-A1 (CA)
Title: Method for preserving cooked bakery products
Inventor: BRYCKAERT EMILIE
IPC: A23L3/3463
Filed: 2020-11-26
Abstract: The invention relates to a method for preparing cooked, mould resistant bakery products, comprising cooking a dough obtained by a sponge and dough type baking method using a poolish containing from 20 to 55 g/L of ethanol, preferably from 35 to 50 g/L of ethanol, and comprising, after cooking, a step of applying a solution to the surface of the cooked bakery product that comprises a live leaven and/or a live yeast.
Patent CA-3162380-A1 (CA)
Title: Fluidifying compounds for hydraulic compositions
Inventor: COLAS ANTOINE
IPC: C04B24/04
Filed: 2020-12-17
Abstract: The invention relates to a compound of formula (I) and to the use thereof, in particular as a chelating agent for positively charged ions or as a fluidizing agent for hydraulic compositions. The invention also relates to a hydraulic composition comprising a compound of formula (I), at least one hydraulic binder, at least one aggregate, and water.
Patent CA-3162951-A1 (CA)
Inventor: YUE BIN
IPC: A61F2/08
Filed: 2020-12-28
Abstract: A rotator cuff balloon (10), comprising a limiting structure (100) and a protective structure (200) that is connected to the limiting structure (100); and the limiting structure (100) is provided with an arc along the coronal plane (102). The rotator cuff balloon (10) conforms to the physiological structure of the human shoulder joint, is limited to the subacromial space, and may reduce adverse events, such as foreign body sensation, dislocation and functional loss, from occurring to a patient. The protective structure (200) is used to support within the gap between the humeral head and the acromion of the human shoulder joint to achieve a supporting effect. Meanwhile, the humeral head of a patient suffering from a rotator cuff injury moves upward, thus preventing pain caused by impact between tissues and also adding a deltoid muscle force applying force arm in order to immediately improve the function of the shoulder joint of the patient. In addition, the limiting structure (100) is used to at least partially fit the humeral head of the human shoulder joint so as to have a limiting effect, and avoid prosthesis displacement.
Patent CA-3166837-A1 (CA)
Inventor: RUSSALIAN VIGEL
IPC: F04D13/02
Filed: 2021-01-08
Abstract: An axial flux motor water pump comprising a housing, a cover attached to the housing, a stator mounted within the housing, the stator comprising a plurality of stator poles mounted in a ring, each stator pole comprising an electric wire winding, a rotor journaled to the housing in cooperating relation to the stator on a single bearing, an impeller fixed to an end of the rotor, a plurality of magnets mounted to an end of the rotor in cooperative relation to the stator poles, a seal between the rotor and housing whereby the stator and magnets are in a dry zone, the stator enrobed in thermal potting within the housing; and power electronics contained in the cover. The rotor portion of the rotor may be manufactured in a sintering process.
Patent CA-3168463-A1 (CA)
Inventor: TOUNG JONATHAN
IPC: G16B40/00
Filed: 2016-12-15
Abstract: Provided herein is a method for distinguishing an aberrant methylation level for DNA from a first cell type, including steps of (a) providing a test data set that includes (i) methylation states for a plurality of sites from test genomic DNA from at least one test organism, and (ii) coverage at each of the sites for detection of the methylation states; (b) providing methylation states for the plurality of sites in reference genomic DNA from one or more reference individual organisms, (c) determining, for each of the sites, the methylation difference between the test genomic DNA and the reference genomic DNA, thereby providing a normalized methylation difference for each site; and (d) weighting the normalized methylation difference for each site by the coverage at each of the sites, thereby determining an aggregate coverage-weighted normalized methylation difference score. Also provided herein are sensitive methods for using genomic DNA methylation levels to distinguish cancer cells from normal cells and to classify different cancer types according to their tissues of origin.
Patent CA-3168705-A1 (CA)
Title: System and method for organ maintenance and transport
Inventor: FILGATE JOSHUA
IPC: A01N1/02
Filed: 2021-02-19
Abstract: System and method for enabling sustained normothermic or subnormothermic perfusion of an organ and for transporting the organ from a donor to a recipient. The system (100) includes a circulation system providing oxygenated perfusate to the organ (135) and enabling continuous monitoring of the perfusate moving through the organ. The tank (123) can provide an inlet that can accept selected infusible materials, and an outlet that can enable sampling and waste removal. The system can continually monitor the solution bath in which the organ is bathed, and the system can manage the composition of the gas in the tank. Direct acting pneumatic pumps can be used to enable minimal hemolysis. The system may comprise a disposable portion and a durable portion.
Patent CA-3169036-A1 (CA)
Inventor: LEFLER Sharon
IPC: A61B5/24
Filed: 2021-01-15
Abstract: L'invention concerne un système de détection qui comprend une microsonde, la microsonde comprenant : une structure en couches comprenant : une unité de détection comprenant un capteur comprenant une électrode de travail, l'unité de détection ayant un premier périmètre lorsqu'elle est vue le long d'une direction de stratification, comprenant un premier matériau ayant une première dureté, et comprenant un premier côté et un second côté ; une couche déformable conçue pour se déformer sous contrainte et positionnée sur le premier côté de l'unité de détection ; une couche ductile positionnée sur la couche déformable à l'opposé de l'unité de détection et ayant un second périmètre lorsqu'elle est vue le long de la direction de stratification, le premier périmètre étant à l'intérieur du second périmètre, la couche ductile comprenant un second matériau ayant une seconde dureté supérieure à la première dureté ; une couche d'interface de capteur positionnée sur le second côté de l'unité de détection ; et un encapsulant encapsulant partiellement la structure en couches et isolant mécaniquement la structure en couches d'un environnement ambiant.
Patent CA-3169417-A1 (CA)
Title: Method of and system for appraising risk
Inventor: LI JIAQING
IPC: G06F40/30
Filed: 2022-07-27
Abstract: The present application provides a method of and a system for appraising risk, of which the method comprises obtaining, from a preset public sentiment text library, a target public sentiment text to which a target object corresponds and whose generating time is within a preset time range;  predicting an event category to which each target public sentiment text corresponds; generating a public sentiment risk score to which the target public sentiment text corresponds; and determining whether to send out first risk early warning to which the target object corresponds according to the public sentiment risk score and a preset first risk early warning threshold, whereby efficiency in collecting public sentiments associated with texts is enhanced, quantitative appraisal of public sentiment risks is realized, and accuracy in recognizing public sentiment risks is ensured.
Patent CA-3170562-A1 (CA)
Title: Salts and polymorphic forms of 6-chloro-7-(4-(4-chlorobenzyl)piperazin-1-yl)-2-(1,3-dimethyl-1h-pyrazol-4-yl)-3h-imidazo[4,5-b]pyridine
Inventor: LOUGHREY JONATHAN
IPC: C07D471/04
Filed: 2021-03-03
Abstract: The present invention relates to salts and polymorphic forms of Compound A (6-chloro-7-(4-(4- chlorobenzyl)piperazin-1-yl)-2-(1,3-dimethyl-1H-pyrazol-4-yl)-3H-imidazo[4,5-b]pyridine), an inhibitor of Aurora kinase and FMS-like tyrosine kinase 3 (FLT3) activity. The present invention also relates to processes for the preparation of the salts and polymorphic forms of the compound, to pharmaceutical compositions comprising them, and to their use in the treatment of proliferative disorders, such as cancer, as well as other diseases or conditions in which Aurora kinase and/or FLT3 activity is implicated.
Patent CA-3170700-A1 (CA)
Inventor: ANDERSON BRETTON
IPC: B25J15/06
Filed: 2021-02-04
Abstract: Est divulgué un organe terminal effecteur pour un dispositif de mouvement programmable destiné à être utilisé au moyen d'une source de vide. L'organe terminal effecteur comprend une partie de fixation d'organe terminal effecteur permettant de fixer l'organe terminal effecteur au dispositif de mouvement programmable, la partie de fixation d'organe terminal effecteur comprenant un canal sous vide accouplé à la source de vide, une partie de contact de l'organe terminal effecteur permettant de mettre en contact un objet devant être acquis par la partie de contact de l'organe terminal effecteur, une section intermédiaire flexible comprenant une extrémité de contact de la partie intermédiaire flexible à proximité de la partie de contact de l'organe terminal effecteur, la section intermédiaire flexible de l'organe terminal effecteur étant intermédiaire entre la partie de fixation d'organe terminal effecteur et la partie de contact de l'organe terminal effecteur, la section intermédiaire flexible comprenant une partie soufflet qui s'étend radialement vers l'extérieur du canal sous vide, et un insert de soufflet qui s'étend dans la section intermédiaire flexible.
Patent CA-3172937-A1 (CA)
Title: Device and system for respiratory support
Inventor: DREVHAMMAR THOMAS
IPC: A61M16/08
Filed: 2020-04-16
Abstract: The present invention relates to a device (100) for positive pressure ventilation (PPV) and continuous positive airway pressure (CPAP) treatment comprising a fresh gas flow inlet (2) arranged to receive a fresh gas flow from a fresh gas flow tube connectable thereto; a patient interface end (3) which is connectable with a patient interface; an outlet (4) having an open end (5); and several variable flow CPAP generators (6), wherein each of the several variable flow CPAP generators is connected with the fresh gas flow inlet, the patient interface end and the outlet of the device. A simplified device and system is provided, respectively, which is easy to use and allows for a rapid switch between PPV and CPAP treatment without change of equipment.