baber/WOPTO huggingface dataset:
Patent AT-E215618-T1 (AT)
Inventor: BRUND KNUD HOUGAARD
IPC: A47J36/02
Filed: 1999-08-30
Granted: 2002-04-15
Abstract: By a method for coating a core body (12), preferably a core body of aluminium, in kitchen utensils, various layers (14, 16, 18, 20, 22) of hard ceramic powder of one or more materials are first applied by means of plasma spraying. An antiadhesion layer (124) is applied to the ceramic layer or layers (14, 16, 18, 20, 22) established of hard ceramic powder material by plasma spraying in one or more steps. By the method the last applied ceramic layer (22) is established by using a hard ceramic powder of a smaller average grain size compared with the other ceramic powder layers, preferably in such a way that the average grain size of the individually applied layers (14, 16, 18, 20, 22) of hard ceramic powder decreases from the core body (12) towards the antiadhesion layer (124). The antiadhesion layer (24) is established by applying, on the latest applied ceramic layer which is established by means of a hard ceramic powder having an average grain size of between 5 and 20 µm, a pigment containing primer enamel containing between 5 and 20%, such as between 10 and 15%, preferably approximately 15% colour pigment by weight and furthermore between 5 and 20%, such as between 10 and 15%, e.g. 15% antiadhesion pigments also by weight, whereas the remainder is constituted by bonding agent, and after the appliance of the pigment containing primer enamel in a wet-wet appliance system, a pigment containing baking enamel containing between 5 and 20%, such as between 10 and 15%, preferably approximately 10% colour pigment by weight and furthermore between 70 and 95%, such as between 75 and 85%, e.g. 80-85% antiadhesion pigments, also by weight, whereas the remainder is constituted by the bonding agent of the baking enamel. Hereby, compared with known methods for coating a core body in kitchen utensils, a better adhesion of the antiadhesion layer to the ceramic layer and, furthermore, a more uniform and cavity free surface of the antiadhesion layer are achieved when as a last ceramic layer a fine-grained ceramic layer is established for providing a close, uniform and smooth ceramic surface without actual cavities.
Patent AT-E229288-T1 (AT)
Inventor: WEIHRAUCH GEORG
IPC: A46B5/00
Filed: 1999-04-07
Granted: 2002-12-15
Abstract: A cleaning brush, particularly toothbrush, has a handle and an elongated brush head, which comprises a flexible bristle carrier tapering in longitudinal cross-section from the handle to the front end of the brush head and bristles fixed thereto. The bristle carrier is formed from two longitudinally, successively arranged portions interconnected in transitionless manner and made from materials having differing characteristics and at least the front portion is made from an elastomer. The materials, cross-sections and bending length of the portions are so chosen that the front portion is deflectable with a smaller radius of curvature than the other portion.
Patent AT-E383132-T1 (AT)
Inventor: BIGE PIERRE ANDRE JACQUES
IPC: A61F9/007
Filed: 1999-05-21
Granted: 2008-01-15
Abstract: The invention relates to a bi-canalicular probe for the treatment of lacrimation of the eye. Said probe substantially comprises a filamentary element (1) made of a biologically inert material, whereby the free ends thereof are provided with retaining means (2) for said filamentary element, forming a stop at the level of the junction between the lacrimal canaliculi and the lacrimal calculus or an opening in the nasal fossa. The probe can be used in the treatment of canalicular stenosis.
Patent AT-E260180-T1 (AT)
Inventor: VOGT WERNER
IPC: B42D15/10
Filed: 1999-08-27
Granted: 2004-03-15
Abstract: A method for producing information carriers in the form of cards, in particular credit cards, passes, identification cards, admittance cards etc., the laminating process including placing at least one card template which is to be sized, preferably a laminate consisting of a plurality of sized card layers, into a hollow mold and subjecting it to a simultaneous action of pressure and heat for a predetermined time. The material placed into the hollow mold is heated over at least one large area, as known per se by the use of heating plates, and in the peripheral, narrow, outer boundary region of the inserted material quantities of heat flowing off per se there are retained, blocked in, reflected and concentrated back onto the laminate template.
Patent AT-E426361-T1 (AT)
Inventor: AEBI MAX
IPC: A61B17/56
Filed: 1999-09-28
Granted: 2009-04-15
Abstract: A distractor for separating adjacent elements, such as vertebrae. The distractor preferably has a scissors-type distracting mechanism, either in a simple scissors or double-acting scissors configuration. A set of blades is provided on each jaw such that an implant may be inserted between the spaced apart blades. The set of blades includes at least two blades.
Patent AT-E236698-T1 (AT)
Inventor: WINTER MARTIN
IPC: F16B4/00
Filed: 1999-08-26
Granted: 2003-04-15
Abstract: A method for producing a sealing connection between a filter mat of a tubular filter element and a metallic head piece encircling the filter element at one end. The head piece has an annular groove accommodating the edge of the filter mat. In order to reduce the internal diameter of the annular groove, the wall adjacent to the periphery is compressed by the periphery of the head piece towards the interior by applying a force of pressure which is directed radially towards the interior. The wall of the annular groove adjacent to the periphery is provided with an enlargement which enlarges the diameter of the head piece. The force of pressure for compressing the wall is applied in the area of said enlargement.
Patent AT-E229589-T1 (AT)
Inventor: HERRING SAMUEL H
IPC: D03D1/00
Filed: 1999-08-30
Granted: 2002-12-15
Abstract: An open ended papermaker's fabric woven from longitudinal and transverse thread systems and including a plurality of seam loops at each end. Two additional transverse threads are interwoven with the longitudinal thread system in the seam zone. The crossover points of the two additional transverse threads occur at a transition between paired paper and machine side threads of the longitudinal thread system which are separated in the transverse direction by at least three top layer longitudinal threads.
Patent AT-E250627-T1 (AT)
Inventor: CRAIG A GREY
IPC: C12N15/09
Filed: 1999-10-20
Granted: 2003-10-15
Abstract: The present invention is directed to contulakin-G (which is the native glycosylated peptide), a des-glycosylated contulakin-G (termed Thr<SUB>10</SUB>-contulakin-G), and derivatives thereof, to a cDNA clone encoding a precursor of this mature peptide and to a precursor peptide. The invention is further directed to the use of this peptide as a therapeutic for anti-seizure, anti-inflammatory, anti-shock, anti-thrombus, hypotensive, analgesia, anti-psychotic, Parkinson's disease, gastrointestinal disorders, depressive states, cognitive dysfunction, anxiety, tardive dyskinesia, drug dependency, panic attack, mania, irritable bowel syndrome, diarrhea, ulcer, GI tumors, Tourette's syndrome, Huntington's chorea, vascular leakage, anti-arteriosclerosis, vascular and vasodilation disorders, as well as neurological, neuropharmalogical and neuropsychopharmacological disorders.
Patent AT-E299113-T1 (AT)
Inventor: TOWNSEND DAVID
IPC: B65D90/52
Filed: 1999-12-02
Granted: 2005-07-15
Abstract: A baffle (1) for reducing hydraulic ram pressure in a liquid in a tank (5,9) in which it is located resulting from impact of a projectile on an external surface (6,10) of the tank, includes at least two outer walls (2) spaced apart to define therebetween at least one cavity (3) and a compressible gas or gaseous mixture at reduced, atmospheric or enhanced pressure contained in the cavity (3). The baffle outer walls (2) are sufficiently strong to withstand the pressure of the gas or gaseous material contained in the cavity (3) are sufficiently strong to resist the hydrostatic pressure of liquid in a tank (5,9), when the baffle (1) is located in the liquid in the tank (5,9), and are spaced apart by an amount sufficient to provide the cavity with a volume sufficient to allow a shock wave or waves in the liquid resulting from compression of the liquid by impact of a projectile on the tank external surface (6) to be reduced by expansion of the compressed liquid into the cavity volume. The gas or gaseous mixture has a density sufficiently different from the density of the liquid to provide substantially total reflection within the baffle (1) of the shock wave or waves impinging on the baffle.
Patent AT-E217240-T1 (AT)
Inventor: GMEILBAUER ENGELBERT
IPC: B26D1/46
Filed: 1999-10-27
Granted: 2002-05-15
Abstract: A tool for cutting out motor vehicle windscreens is described, with a suction cup, a rotating head pivotable on the latter, a cutting wire and a spring between the rotating head and the end of the wire. The spring is a compression spring which is arranged between the rotating head and the inner end of the cutting wire so that the spring is compressed when the cutting wire is pulled, and extends when the wire is released, drawing the wire inwards.
Patent AT-E307340-T1 (AT)
Inventor: HERSHEY GURJIT K KHURANA
IPC: G01N33/53
Filed: 1999-12-10
Granted: 2005-11-15
Abstract: A method for determining whether an individual is susceptible for asthma is disclosed. In addition, a method for predicting the severity of asthma in a patient is also disclosed. These methods involve determining whether an individual carries an allelic variation in the IL-4 receptor that leads to increased receptor signaling as a predictor of asthma and asthma severity.
Patent AT-E252993-T1 (AT)
Inventor: REIMER ERNEST M
IPC: G01L5/00
Filed: 1999-11-26
Granted: 2003-11-15
Abstract: A collision deformation sensor for use within the crush zone of a vehicle consists of first and second spaced apart substrates for mounting to or forming respective vehicle components, with a compressible carrier medium filling the space between the substrates. The carrier medium is formed from a material transparent or translucent to light or other wave energy, and includes wave energy scattering centers dispersed within the medium to create a scattered energy volume. Alternatively the carrier medium forms a hollow cavity, the inside surface of which is coated with a wave energy dispersion coating. A source and receiver of light or other wave energy communicates with the carrier medium. Signal couplings and processors are associated with the source and receiver. The device operates on the principle whereby compression of the space between the substrates increases the intensity of a light or other wave energy, and this increase is detected by the receiver and signal processor, which in turn activates an air bag, or seat belt tightener or the like.
Patent DE-02744727-T1 (DE)
Title: Verfahren zur herstellung eines fluorierungskatalysators
Inventor: TUNG SUNG
IPC: B01J23/26
Filed: 2002-06-28
Abstract: Verfahren
zur Herstellung eines zur Verwendung bei der Fluorierung einer organischen
Verbindung geeigneten Katalysators, bei dem man eine katalytisch
aktive Verbindung bei ungefähr
der Arbeitstemperatur und dem Arbeitsdruck des Katalysators unter
solchen Bedingungen mit einem ersten Aktivierungsmittel behandelt, daß man bei
ungefähr
der Arbeitstemperatur und dem Arbeitsdruck einen weitgehend stationären Zustand
erreicht.
Patent DE-03022772-T1 (DE)
Inventor: FREDERIKSEN NIELS
IPC: F16K1/30
Filed: 2003-10-10
Abstract: A flow control valve for cylinders of liquefied gases having a means for indicating the status of the fluid, comprises a body (2) in which there is a region (22) provided with a shank (4) that is adapted to be connected to a cylinder, a region (5) for connection to user devices, a safety valve (26) and a moveable actuation member (3,15), the actuation of which blocks the passage (12) for the fluid from the cylinder toward the user device or clears the passage, characterized in that a pressure sensing means (14) is accomodated inside the actuation member (3,15). <IMAGE>
Patent DE-10767394-T1 (DE)
Title: Kindertrage
Inventor: BERGKVIST HAKAN
IPC: A47D13/02
Filed: 2010-04-21
Abstract: Tragvorrichtung für Kleinkinder, die zum Tragen eines Kinds entweder in einer Position Angesicht zu Angesicht oder in nach vorne weisender Position ausgeführt ist, umfassend Brustgurte (1), die so angeordnet sind, dass sie sich um beide Schulterbereiche des Trägers erstrecken, einen Hüftgurt (2), der mit den Brustgurten verbunden ist, und eine Tragetasche (3), die an den Brustgurten und am Hüftgurt angebracht ist und ein Vorderteil (4) umfasst, das zusammen mit mindestens den Brustgurten (1) einen Tragbeutel (5) bildet, der Beinöffnungen aufweist, wobei mindestens der untere Abschnitt des Vorderteils (4) mit dem Hüftgurt (2) verbunden ist und einen ersten Sitzträger (12) bildet, und sich das Vorderteil (4) an einem oberen Abschnitt (7) befindet, der durch eine Verbindungsvorrichtung (8) lösbar mit dem jeweiligen Brustgurt (1) verbunden ist, wobei ein zweiter, breiterer Sitzträger (9) zumindest teilweise lösbar zwischen dem Hüftgurt (2) und einem Bereich des Vorderteils (4) auf einer Höhe, die dem Hüftgurt...
Patent DE-69579-T1 (DE)
IPC: F16J1/22
Filed: 1982-07-05
Abstract: A piston is formed by a metal sleeve (14) heat shrunk onto a core (24) of refractory material, preferably a ceramic. The core (24) has a hemi-spherical recess (32) in its inner end and the connecting rod (12) has a ball head (34) trapped in this recess by a retaining ring (13) screwed into the inner end of the sleeve (14). The core (24) is pre-stressed in compression and remains compressively stressed throughout the engine operating cycle and thus free from risk of cracking.
Patent DE-241263-T1 (DE)
IPC: B32B7/08
Filed: 1987-04-07
Abstract: Conventionally absorbent sheets for meat packaging are made of absorbent cellulose laminations 18 with a cover sheet 14 of polyethylene. The laminations are compression bonded by means of a serrated wheel which forms a series of indentations along one or more lines. When moisture is absorbed the sheet 14 tends to delaminate. To prevent this a thermo-setting material such as a wax is applied along the line of indentations. A wax rivet 24 is thus formed which provides additional mechanical bonding and prevents access of moisture to the immediate region of the compression bond 22 by reason of the absorbed wax 24A.
Patent DE-648459-T1 (DE)
Inventor: COUDURIER ALAIN
IPC: A47J36/02
Filed: 1994-10-12
Abstract: The cooking vessel is made from a disc (3) of metal or light alloy. It comprises a bottom (1) intended to be laid on a hotplate, burner or the like. The bottom (1) comprises a plate (2) in a metal having different properties from those of the metal of the disc (3). This plate (2) is fully or partly let into the bottom (1) and its circumference may adjoin a groove (4). For improving the resistance to the deformation of the bottoms of cooking vessels. <IMAGE>
Patent ES-2047470-T1 (ES)
Title: Pila alcalina asistida por aire.
Inventor: REICHERT SAMUEL FIRESTONE
IPC: H01M50/489
Filed: 1993-04-02
Abstract: UNA PILA ALCALINA ASISTIDA POR AIRE TIENE UN ANODO QUE CONTIENE ZINC, ENCERRADO DENTRO DE UN SEPARADOR DE FORMA CILINDRICA DE EXTREMOS CERRADOS (COMO PUEDE SER CON CELOFAN), QUE ES BASICAMENTE PERMEABLE AL HIDROGENO Y BASICAMENTE IMPERMEABLE AL ELECTROLITO DE LA PILA, Y QUE TIENE UN REVESTIMIENTO DE GEL (COMO PUEDE SER EL ALMIDON) DEPOSITADO EN UN AREA DEL ANODO EXPUESTA DENTRO DEL SEPARADOR, DE FORMA QUE EL ELECTROLITO ENTRARA SUBSTANCIALMENTE DENTRO DEL COMPARTIMENTO DEL REVESTIMIENTO DE GEL/SEPARADOR DEL ANODO, MIENTRAS QUE EL HIDROGENO ESTARA LIBRE PARA SALIR DE DICHO COMPARTIMENTO.
Patent ES-2103693-T1 (ES)
Title: Rodillo de flexion con autocarga hidrostatica controlada.
Inventor: BROWN DALE A
IPC: F16C13/00
Filed: 1995-08-10
Abstract: EL RODILLO DE DEFLEXION HIDROSTATICO, AUTOCARGABLE, CONTROLADO TIENE UNA ZAPATA CENTRAL, HIDRAULICAMENTE ACCIONADA QUE SE EXTIENDE SUBSTANCIALMENTE POR LA ANCHURA COMPLETA DE LA CUBIERTA DEL RODILLO GIRATORIO (1) Y DOS ZAPATAS EXTERNAS (24, 26, 28, 30) DISPUESTAS EN LA DIRECCION DE CORTE DE LA MAQUINA, FUERA DE LA ZONA DE CARGA. EL USO DE ZAPATAS EXTERNAS PERMITE EL USO DE UNA ZAPATA SIMPLE DE MORDISCO DE LONGITUD COMPLETA (3) DENTRO DE LA ZONA DE CARGA, QUE SIMPLIFICA EL CONTROL Y SUMINISTRA UNA DISTRIBUCION DE TEMPERATURA MAS UNIFORME. LAS ZAPATAS EXTERNAS (24, 26, 28, 30) TAMBIEN SUMINISTRAN UN MEJOR CONTROL DE CORONA. LAS ZAPATAS ESTAN PREFERIBLEMENTE DISPUESTAS DENTRO DE UN AREA DE LA PESTAÑA DE CABEZA (17, 18) DEL RODILLO, EN LA UBICACION EN LA QUE LOS COJINETES ESFERICOS ESTARIAN NORMALMENTE PRESENTES EN UN RODILLO CONVENCIONAL. EL ARO DEL COJINETE ESTA DISPUESTO AXIALMENTE FUERA DE LA PESTAÑA DE CABEZA Y ALREDEDOR DE UNA PARTE DE LA CAJA DE COJINETE EN CUALQUIER EXTREMO DEL RODILLOPARA SOPORTAR GIRATORIAMENTE LA CUBIERTA DEL RODILLO ALREDEDOR DE LOS COJINETES EN LA CAJA DE COJINETES. SE DISPONE UN SELLAMIENTO DE BARRERA ENTRE EL EJE DEL RODILLO ESTACIONARIO Y LA CUBIERTA DEL RODILLO (1) DE FORMA INTERMEDIA A LOS COJINETES Y A LAS ZAPATAS EXTERNAS (24, 26, 28, 30).
Patent ES-2171368-T1 (ES)
Title: Una formulacion y un procedimiento para aumentar la resistencia de plantas a agentes patogenos y a la tension ambiental, que emplea quitosan.
Inventor: VILLANUEVA JAIME
IPC: A01N43/16
Filed: 1996-09-05
Abstract: LA INVENCION SE REFIERE A METODOS Y COMPOSICIONES PARA TRATAR EL SISTEMA DE RAICES DE RETOÑOS Y PLANTAS JOVENES. EJEMPLOS DE LAS PLANTAS A TRATAR INCLUYE ESPECIES FORESTALES, QUE SE EJEMPLIFICAN COMO MIEMBROS DE LAS FAMILIAS DE CONIFERAS Y EUCALIPTOS; ESPECIES HORTICOLAS, TALES COMO ESPARRAGOS Y TOMATES; Y OTRAS PLANTAS AGRICOLAMENTE IMPORTANTES TALES COMO EL TABACO Y BALLAS. EL TRATAMIENTO MEJORA LA RESISTENCIA DE LAS PLANTAS A LAS PLAGAS Y LA SUPERVIVENCIAS A CONDICIONES MEDIO AMBIENTALES ADVERSAS. LOS RESULTADOS INCLUYEN MEJORAS TOTALES, SIGNIFICATIVAS EN EL CRECIMIENTO Y EN EL RENDIMIENTO DE LAS PLANTAS FORESTALES, HORTICOLAS Y OTRAS.
Patent ES-2119732-T1 (ES)
Inventor: COULAND CHARLES
IPC: H04L25/02
Filed: 1997-10-31
Abstract: The termination includes a multilayer personal computer (4) with rectangular shape presenting an area (5) containing signal processing components (6). Two connectors (7,8) make the connection to the network line (U) and the subscriber line (S). A capacitive connection between the two connectors is provided to protect the signal processing components against transient electromagnetic noise.
Patent ES-2132057-T1 (ES)
Title: Accesorio para conducto de cableado electrico.
Inventor: ALBERT CHRISTOPHE
IPC: H02G3/04
Filed: 1998-10-07
Abstract: ACCESORIO DE RECUBRIMIENTO PARA CONDUCTO DE CABLEADO ELECTRICO, COMO POR EJEMPLO UNA CONTERA. SEGUN LA INVENCION EL ACCESORIO LLEVA UNA PARTE DE RECUBRIMIENTO (25) QUE SE ENCAJA SOBRE EL CONDUCTO Y QUE LLEVA INTERIORMENTE NERVIOS (30, 31) SUSCEPTIBLES DE INCRUSTARSE EN UN ALA DE TAL CONDUCTO, PARTICULARMENTE EN UN ANILLO (22).
Patent ES-2142302-T1 (ES)
Title: Caja de encastre con cuerpo de caja y pie que prolonga lateralmente el cuerpo de la caja, principalmente para aparato electrico.
Inventor: JADAUD ALAIN
IPC: H02G3/10
Filed: 1999-06-08
Abstract: LA INVENCION SE REFIERE A UNA CAJA DE EMPOTRAR QUE COMPRENDE UN CUERPO DE CAJA (11) QUE FORMA UN ALOJAMIENTO (12), Y UN PIE (13) QUE PROLONGA LATERALMENTE EL CUERPO DE CAJA (11), QUE FORMA TAMBIEN UN ALOJAMIENTO (14). SEGUN LA INVENCION, EL PIE (13) CONSTITUYE UNA PIEZA DISTINTA DEL CUERPO DE CAJA (11), Y EN UNA PARTE AL MENOS DE SU LONGITUD, A PARTIR DE LA DE SUS EXTREMOS POR EL CUAL ESTA DESTINADO A UNIRSE A ESTE CUERPO DE CAJA (11), ESTA SEGMENTADO LONGITUDINALMENTE EN SECCIONES (26) SUCESIVAS CON, ASOCIADOS A CADA UNO DE ESTAS SECCIONES (26), MEDIOS DE INTRODUCCION (27), QUE, EN COOPERACION CON MEDIOS DE INTRODUCCION (28) PREVISTOS DE MANERA COMPLEMENTARIA EN CORRESPONDENCIA EN EL CUERPO DE CAJA (11) EN AL MENOS UN LUGAR DE ESTE, SON APTOS PARA PERMITIR SU SOLIDARIZACION A ESTE ULTIMO. APLICACION, EN PARTICULAR EN LOS APARATOS ELECTRICOS.
Patent CY-1107099-T1 (CY)
Inventor: IDUSOGIE ESOHE EKINADUESE
IPC: C07K19/00
Filed: 2007-12-19
Abstract: A variant of a polypetide comprising a human IgG Fc region is described, which variant comprises an amino acid substitution at one or more of amino acid positions 270, 322, 326, 327, 329, 331, 333 or 334 of the human IgG Fc region. Such variants display altered effector function. For example, C1q binding and/or complement dependent cytotoxicity (CDC) activity may be altered in the variant polypeptide. The application also discloses a variant of a parent polypeptide comprising a human IgG Fc region, which variant has a better binding affinity for human C1q than the parent polypeptide.
Patent CY-1107855-T1 (CY)
Inventor: DICKASON DAVID A
IPC: A61K47/10
Filed: 2008-01-11
Abstract: A non-aqueous, particle-forming, fused pyrrolocarbazole-containing composition is disclosed. Upon contact with an aqueous medium, the particle-forming composition spontaneously disperses into suspended particles, thereby forming a stable suspension that provides greatly improved bioavailability of orally administered fused pyrrolocarbazole compounds.
Patent CY-1108727-T1 (CY)
Inventor: YAMASHITA M
IPC: A61K31/137
Filed: 2009-01-27
Abstract: This invention provides a convenient and industrially advantageous process producing amine derivatives having the action of inhibiting the secretion and accumulation of amyloid  beta  protein. <CHEM>   In Compound (I), the ether linkage is selectively cleaved without cleaving the amide linkage present in the same molecule and tertiary amines are not converted into quaternary salts, and thus Amine Derivative (V) with good qualities having the action of inhibiting the secretion and accumulation of amyloid  beta  protein can be obtained in high yield.
Patent CY-1108879-T1 (CY)
Inventor: DI CESARE MARIA A
IPC: A61P25/24
Filed: 2009-03-06
Abstract: Compounds of Formula (I): (I); wherein: R<SUB>1 </SUB>and R<SUB>2 </SUB>either the same or different, are H or linear or branched C<SUB>1</SUB>-C<SUB>6 </SUB>alkyl; R<SUB>3</SUB>=linear or branched C<SUB>1</SUB>-C<SUB>6 </SUB>alkyl; R<SUB>4</SUB>=halogen, and pharmaceutically acceptable salts thereof are useful as active ingredients in the preparation of medicaments used as ligands of the 5-HT<SUB>6 </SUB>and/or 5-HT<SUB>7 </SUB>serotoninergic receptors.
Patent CY-1109062-T1 (CY)
Inventor: VARNER JUDITH A
IPC: A61K38/08
Filed: 2009-05-14
Abstract: The present invention provides methods for reducing or inhibiting angiogenesis in a tissue, by contacting ±5²1 integrin in the tissue with an agent that interferes with specific binding of the ±5²1 integrin to a ligand expressed in the tissue; and methods of identifying angiogenesis in a tissue, by contacting the tissue with an agent that specifically binds ±5²1 integrin, and detecting specific binding of the agent to ±5²1 integrin associated with a blood vessel in the tissue. Also provided are methods of diagnosing a pathological condition characterized by angiogenesis in a tissue in an individual. The invention further provides methods of reducing or inhibiting angiogenesis in a tissue in an individual, by administering to the individual an agent that interferes with the specific binding of ±5²1 integrin to a ligand expressed in the tissue; and methods of reducing the severity of a pathological condition associated with angiogenesis in an individual, by administering to the individual an agent that interferes with specific binding of ±5²1 integrin to a ligand in a tissue associated with the pathological condition. The invention also provides methods of identifying an agent that reduces or inhibits angiogenesis associated with ±5²1 integrin expression in a tissue by contacting a tissue exhibiting angiogenesis associated with ±5²1 integrin expression with an agent, and detecting a reduction or inhibition of angiogenesis in the tissue.