baber/WOPTO huggingface dataset:
Patent AU-2018350992-A1 (AU)
Title: Fully-human post-translationally modified antibody therapeutics
Inventor: DANOS OLIVIER
IPC: C07K16/24
Filed: 2018-10-17
Abstract: Provided are methods and compositions for the delivery of fully human post-translationally modified therapeutic monoclonal antibodies and antigen-binding fragments thereof. The fully human post-translationally modified therapeutic monoclonal antibodies may be preferably delivered by gene therapy methods, particularly as a recombinant adeno-associated virus (rAAV) vector to the appropriate tissue. Methods of manufacture of the AAV vectors, pharmaceutical compositions and methods of treatment are also provided. In addition, provided are methods of producing therapeutic antibodies that are "biobetters" as fully human post-translationally modified. These fully human post-translationally modified therapeutic antibodies may be administered to a subject in need of treatment with the therapeutic antibody.
Patent AU-2018352470-A1 (AU)
Title: Heatable food container
Inventor: KILPATRICK DAVID GEORGE
IPC: B65D81/34
Filed: 2018-10-16
Abstract: A container for heating a food product via an energy source, the container comprising a surface defining an inner volume within the container for receiving the food product, wherein the surface is adapted to direct energy of the energy source to a particular location of the food product for heating of the food product. A heatable container for heating a food product via an energy source, the container comprising a surface defining an inner volume within the container for receiving the food product, wherein the surface comprises a plurality of sections adapted to be assembled together for defining the container.
Patent AU-2018390922-A1 (AU)
Title: A body fluid leakage detection aqueous composition
Inventor: JOHANSSON HENRIK
IPC: A61K49/00
Filed: 2018-12-20
Abstract: A body fluid leakage detection aqueous composition, for use e.g. in intraoperative pancreatic fluid leakage detection. The composition comprises a gelling agent, increasing the viscosity of the composition, and buffering species, the composition thereby being buffered. The gelling agent is cross-linked α-glucan microspheres. Further, the composition comprises a pH-indicator. The pH of the composition is at least 0.1 pH units lower, or higher, than a p
Patent AU-2018409008-A1 (AU)
Title: Method and device for transmitting information
Inventor: LIN YANAN
IPC: H04W72/04
Filed: 2018-02-13
Abstract: Disclosed in an embodiment of the present invention are a method and device for transmitting information. The method comprises: a terminal device receiving first information transmitted by a network device; the terminal device determining, from uplink transmission resources, and according to the first information, a first resource for transmitting uplink control information; and the terminal device using the first resource to transmit the uplink control information.
Patent AU-2018434435-A1 (AU)
Title: Resource configuration method and device, terminal device and network device
Inventor: YOU XIN
IPC: H04W74/08
Filed: 2018-07-26
Abstract: Provided by the embodiments of the present application are a resource configuration method and device, a terminal device and network device, the method comprising: a terminal device receiving first configuration information sent by a network device, the first configuration information comprising resource configuration information of at least one uplink transmission resource, the at least one uplink transmission resource being used to transmit a first message during a random access process, wherein the at least one uplink transmission resource is configured on the basis of the priority level of the random access process.
Patent AU-2019202301-A1 (AU)
Title: Lifting mechanism
Inventor: LYKKEGAARD FRANK J
IPC: B66F7/00
Filed: 2019-04-03
Abstract: A platform link mechanism may include a base with a first member rotatably coupled to the base. A second member may be coupled to the first member. The second member may be moveable with respect to the first member between a first position and a second position. A lifting link assembly may be rotatably coupled to each of the base and the second member. A platform mount may be coupled to the second member. The platform mount may be rotatable about a platform pivot with respect to the second member. The lifting link assembly may rotate relative to the first member, the second member, and the base as the second member moves relative to the first member. The first member may rotate relative to the base as the lifting link assembly rotates relative to the first member. 54t
Patent AU-2019202822-A1 (AU)
Title: Methods and compositions for enhancing hair quality using blackberry extract
Inventor: BRUNING ELIZABETH
IPC: A61P17/14
Filed: 2019-04-23
Abstract: Compositions and methods for inducing hair growth and improving hair quality utilizing extracts of blackberry in an amount effective to induce hair growth when applied topically to an area of the skin on which hair growth is desired.
Patent AU-2019204977-A1 (AU)
Title: Modulation of prekallikrein (pkk) expression
Inventor: FREIER SUSAN M
IPC: A61K31/7115
Filed: 2019-07-11
Abstract: Disclosed herein are antisense compounds and methods for decreasing PKK mRNA and protein expression. Such methods, compounds, and compositions are useful to treat, prevent, or ameliorate PKK-associated diseases, disorders, and conditions.
Patent AU-2019229186-A1 (AU)
Title: Guidewire retention device
Inventor: BIERMAN STEVEN F
IPC: A61M25/09
Filed: 2019-02-26
Abstract: The device includes a dilator with a hub (38) and an elongated body (36). A locking mechanism (30) is configured to limit a distance a guidewire (28) can be advanced out of a distal end of the dilator. The guidewire has a guidewire stop (92B) being receivable through the elongated dilator body (36). The guidewire lock (30) having at least one member being moveable between an engaged state and a non-engaged state and being biased toward the engaged state in which the guidewire lock interacts with the guidewire. The locking mechanism and the dilator are configured to permit removal of the locking mechanism (30) from the dilator by moving the guidewire (28) axially in a proximal direction relative to the dilator with the guidewire stop abutting at least part of the portion of the locking mechanism that an opening extends through.
Patent AU-2019229256-A1 (AU)
Title: Compounds with ferroptosis inducing activity and methods of their use
Inventor: JIANG CHUN
IPC: C07D217/14
Filed: 2019-02-27
Abstract: This present disclosure relates to compounds with ferroptosis inducing activity, a method of treating a subject with cancer with the compounds, and combination treatments with a second therapeutic agent.
Patent AU-2019230219-A1 (AU)
Title: Proteomic assay using quantum sensors
Inventor: CLEVELAND JASON PAUL
IPC: G01N21/78
Filed: 2019-03-08
Abstract: Apparatus and methods for the detection of proteins in biological fluids such as urine using a label-free assay is described. Specific proteins are detected by their binding to highly specific capture reagents such as SOMAmers that are attached to the surface of a substrate. Changes to these capture reagents and their local environment upon protein binding modify the behavior of color centers (e.g., fluorescence, ionization state, spin state, etc.) embedded in the substrate beneath the bound capture reagents. These changes can be read out, for example, optically or electrically, for an individual color center or as an average response of many color centers.
Patent AU-2019232940-A1 (AU)
Title: Seismic data acquisition with dual/triple sources and hexa-source
Inventor: ELBOTH THOMAS
IPC: G01V1/22
Filed: 2019-09-20
Abstract: A method for configuring a multi-source and a hexa-source for acquiring first and second seismic datasets of a subsurface. The method includes selecting a number n of source arrays to create the multi-source; selecting a number m of sub-arrays for each source array, each sub-array having a plurality of source elements; imposing a distance D between any two adjacent source arrays of the multi-source; calculating a distance d between any two adjacent sub-arrays of a same source array so that bins associated with the first and second seismic datasets are interleaved; selecting source elements from at least six different sub-arrays of the n source arrays to create the hexa-source; and firing the multi-source to acquire the first dataset, and firing the hexa-source to acquire the second dataset. SELECTING A NUMBER N OF SOURCE ARRAYS TO CREATE THE MULTI-SOURCE 00 SELECTING A NUMBER m OF SUB-ARRAYS FOR EACH SOURCE ARRAY, EACH SUB-ARRAY 1102 HAVING A PLURALITY OF SOURCE ELEMENTS IMPOSING A DISTANCE D BETWEEN ANY TWO ADJACENT SOURCE ARRAYS OF THE MULTI SOURCE 04 CALCULATING A DISTANCE d BETWEEN ANY TWO ADJACENT SUB-ARRAYS OF A SAME SOURCE ARRAY SO THAT BINS ASSOCIATED WITH THE FIRST AND 1106 SECOND SEISMIC DATASETS ARE INTERLEAVED SELECTING SOURCE ELEMENTS FROM SIX DIFFERENT SUB-ARRAYS TO CREATE THE 1108 HEXA-SOURCE FIRING THE MULTI-SOURCE TO ACQUIRE THE FIRST DATASET, AND FIRING THE HEXA-SOURCE TO 1110 ACQUIRE THE SECOND DATASET
Patent AU-2019239850-A1 (AU)
Title: High affinity neutralizing monoclonal antibodies to programmed death ligand 1 (PD-L1) and uses thereof
Inventor: SHIMKETS RICHARD
IPC: C07K16/28
Filed: 2019-03-19
Abstract: Disclosed herein are novel PD-L1 binding molecules and methods of their use. The disclosed PD-L1 binding molecules include neutralizing anti-PD-L1 antibodies, bi-specific antibodies, and immunotoxins. The description provides for the use of the disclosed PD-L1 binding molecules in the treatment, prevention, inhibition, or reduction of a cancer or metastasis or as part of a treatment regimen including the use of other anti-cancer agents.
Patent AU-2019264645-A1 (AU)
Title: Interleukin-2 muteins for the expansion of T-regulatory cells
Inventor: BUTZ ERIC ALAN
IPC: C07K14/55
Filed: 2019-11-15
Abstract: Provided herein are IL-2 muteins, IL-2 mutein Fc-fusion molecules, anti-IL-2 antibodies, and complexes comprising an anti IL-2 antibody bound to an IL-2 cytokine that preferentially expand and activate T regulatory cells and are amenable to large scale production. Also provided herein are variant human IgGI Fc molecules lacking or with highly reduced effector function and high stability despite lacking glycosylation at N297. Also provided herein are linker peptides that are glycosylated when expressed in mammalian cells. Also provided herein are methods of making and using the compositions of the present invention.
Patent AU-2019271914-A1 (AU)
Title: Stacking Type Hydrogen Generating Device
Inventor: LIN HSIN-YUNG
IPC: C25B9/17
Filed: 2019-11-26
Abstract: The present invention provides a stacking type hydrogen generating device comprising an electrolysis module, a water tank, a filter and a humidifier. The electrolysis module is disposed in the water tank, the 5 humidifier vertically stacked above the water tank, and the filter vertically stacked above the humidifier. A gas comprising hydrogen generated by the electrolysis module can enter the filter through the first flow channel of the humidifier and enter the humidifier after filtered by the filter. The flow channels between the aforementioned units are respectively integrated with 10 the aforementioned units. Accordingly, the volume and the pipelines of the stacking type hydrogen generating device could be decrease and safety could be improved.
Patent AU-2019271943-A1 (AU)
Title: Double-gripper for the application of teat cups to an animal to be milked, rinse cup for this and milking machine provided therewith, and a method for milking
Inventor: HOFMAN HENDRICK
IPC: A01J5/017
Filed: 2019-11-26
Abstract: A robotic attacher, comprising a gripping portion having a first grabber positioned side-by-side with a second grabber, wherein the first grabber comprises: a first magnet stored in a first housing and operable to contact a first teat cup; and a first cylinder configured to extend the first magnet such that the first magnet contacts the first teat cup, and to retract the first magnet such that the first magnet releases the first teat cup. The second grabber comprises: a second magnet stored in a second housing and operable to contact a second teat cup; and a second cylinder configured to extend the second magnet such that the second magnet contacts the second teat cup, and to retract the second magnet such that the second magnet releases the teat cup. (FIG. 2) C%4J ra-
Patent AU-2019282801-A1 (AU)
Title: Securing device for tool
Inventor: FLORES JESUS
IPC: B25H3/00
Filed: 2019-06-07
Abstract: A case for a tool having a pocket with a base panel, first and second side panels, first and second end panels, and first and second slots. A first strap having a first proximal end affixed to the pocket first and a first distal end and a second strap having a second proximal end affixed to the pocket and a second distal end. The first and second straps are configured to wrap the tool, and the first distal end is configured to pass through the first slot and the second distal end is configured to pass through the second slot.
Patent AU-2019294236-A1 (AU)
Title: Sulfur-containing polyether surfactants for cement spacer fluids and other downhole applications
Inventor: BISHOP MARSHALL D
IPC: C09K8/40
Filed: 2019-06-20
Abstract: Spacer fluid compositions comprising water, a clay, and a sulfur-containing polyether surfactant are disclosed, and such compositions often can further include a weighting additive, an antifoaming additive, and a co-solvent. These spacer fluid compositions can be used to treat metal casing and to remove drilling fluid residue for improved cement bonding in wellbore applications.
Patent AU-2019323450-A1 (AU)
Title: Pyridinylmethylenepiperidine derivatives and uses thereof
Inventor: JIN CHUANFEI
IPC: C07D401/02
Filed: 2019-08-22
Abstract: Disclosed are pyridinylmethylenepiperidine derivatives and uses thereof, specifically, a novel pyridinylmethylenepiperidine compound and a pharmaceutical composition containing this compound, which may be used for activating 5-HT
Patent AU-2019335968-A1 (AU)
Title: Heterocyclic compound
Inventor: OHDACHI KAZUHIRO
IPC: A61K31/519
Filed: 2019-09-06
Abstract: Provided is a novel heterocyclic compound having an aryl hydrocarbon receptor antagonist activity and useful for the promotion of platelet production, the compound being represented by the general formula [I]: wherein ring A, ring B, R
Patent AU-2019336598-A1 (AU)
Title: Wet-mate retrievable filter system
Inventor: LOH YUH
IPC: E21B43/10
Filed: 2019-08-05
Abstract: A mandrel (11) in production tubing within a well has a side pocket (15) with an inlet port (21) for connection to an upper control line segment (19). An outlet port (22) is below the inlet port for connection to a lower control line segment (23). A filter assembly (25) is lowered through the production tubing into the pocket. A valve (41) at a lower end of the pocket is movable from a closed position closing the outlet port to an open position opening the outlet port. A probe (37) mounted to a lower end of the filter assembly engages and pushes the valve element from the closed position to the open position while the filter assembly is being seated in the pocket.
Patent AU-2019360608-A1 (AU)
Title: Combination therapy utilizing DNA alkylating agents and ATR inhibitors
Inventor: DEUTSCH CARL
IPC: A61K31/437
Filed: 2019-10-14
Abstract: The present invention relates to synergistic combinations of DNA-alkylating ADCs and ATR inhibitors.
Patent AU-2019362389-A1 (AU)
Title: Compounds containing deuterium
Inventor: LEHMANN FREDRIK
IPC: C07K5/06
Filed: 2019-10-17
Abstract: The invention provides a compound of formula (I), or a pharmaceutically acceptable salt thereof (Formula I), wherein, each R
Patent AU-2019370424-A1 (AU)
Title: Video picture prediction method and apparatus
Inventor: CHEN HUANBANG
IPC: H04N19/105
Filed: 2019-10-23
Abstract: A video image prediction method and apparatus, providing a method for determining the maximum length of a candidate motion vector list of a sub-block merge mode. The method comprises: parsing a first identifier from a code stream; when the first identifier indicates that a candidate mode used by a block to be processed for implementing interframe prediction comprises an affine mode, parsing a second identifier from the code stream, the second identifier being used for indicating the maximum length of a first candidate motion vector list, the first candidate vector motion list being a candidate motion vector list constructed when the block to be processed uses a sub-block merge prediction mode; and, on the basis of the second identifier, determining the maximum length of the first candidate motion vector list.
Patent AU-2019375476-A1 (AU)
Title: Pore
Inventor: REMAUT HAN
IPC: C12Q1/6869
Filed: 2019-11-07
Abstract: A system for characterising a target polynucleotide, the system comprising a membrane and a pore complex; wherein the pore complex comprises: (i) a nanopore located in the membrane, and (ii) an auxiliary protein or peptide attached to the nanopore; wherein the nanopore and the auxiliary protein or peptide together form a continuous channel across the membrane, the channel comprising a first constriction region and a second constriction region; wherein the first constriction region is formed by a portion of the nanopore, and wherein the second constriction region is formed by at least a portion of the auxiliary protein or peptide.
Patent AU-2019375921-A1 (AU)
Title: Plants with a cannabinoid profile enriched for cannabidiol
Inventor: ELKINS AARON CHRISTOPHER
IPC: A61K36/185
Filed: 2019-11-08
Abstract: The present disclosure relates generally to new cannabis plants, including parts, extracts and uses thereof, comprising a cannabinoid profile enriched for total CBD (
Patent AU-2019397565-A1 (AU)
Title: Methods for the treatment of depression
Inventor: LOYA CARLOS
IPC: A61P25/24
Filed: 2019-12-16
Abstract: The invention relates to methods of treating depression with Compound 1 or pharmaceutically acceptable salts thereof. The present disclosure, among other things, provides methods of treating depression by administering a therapeutically effective amount of Compound 1 or a pharmaceutically acceptable salt thereof to a patient in need thereof. In another aspect, the present invention provides methods of treating a mood or affective disorder selected from perimenopause, generalized anxiety disorder, panic disorder, social anxiety disorder, post-traumatic stress disorder, acute stress disorder, specific phobia, and selective mutism by administering a therapeutically effective amount of Compound 1 or a pharmaceutically acceptable salt thereof to a patient in need of thereof.
Patent AU-2019419383-A1 (AU)
Title: Virtual synchronous generator system and method
Inventor: GONG MAOZHONG
IPC: H02J3/38
Filed: 2019-12-24
Abstract: A virtual synchronous generator device (110) disclosed. The device includes an inverter (212) and inverter controller (231) having a power control portion (275), a power reserve portion (264), a power point tracking control portion (253), and a virtual inertia control portion (242). The power reserve portion determines an amount of power to be reserved and sends a signal, indicative of the determined amount of power to the power point tracking controller. The power point tracking controller determines a power point that is less than a MPP, and provides a signal to the power control portion indicative of the determined power point. The inertia control portion determines a virtual inertia and provides a signal indicative of the virtual inertia to the power control portion. The power control portion provides a power control signal to the inverter based on the power point tracking signal and the inertia command signal.
Patent AU-2019433629-A1 (AU)
Title: Tracking image senders on client devices
Inventor: LI SHUZHEN
IPC: H04L29/00
Filed: 2019-03-12
Abstract: Methods and systems for tracking image senders using client devices are described herein. A computing system may receive an image containing a first watermark vector corresponding to a user account of an image sender. The computing system may convert the image to a frequency domain image that contains the first watermark vector. From the frequency domain image, the computing system may identify the first watermark vector. The computing system may compare the first watermark vector to each of a plurality of stored watermark vectors, each corresponding to a known user account, to determine a probability of a match. The computing system may determine the user account of the sender of the image by determining which of the plurality of stored watermark vectors has a highest probability of a match, and may send, to a workplace administrator platform, an indication of the user account.
Patent AU-2019455808-A1 (AU)
Title: Multi-station adaptive walnut shell pre-breaking system
Inventor: LI CHANGHE
IPC: A23N5/00
Filed: 2019-10-29
Abstract: The present invention discloses a multi-station adaptive walnut shell pre-breaking system, 
comprising a feeding device and a shell pre-breaking device. The feeding device comprises a 
feeding box, a single-helix twister and a double-helix twister are disposed in the feeding box, the 
single-helix twister and the double-helix twister rotate in opposite directions, and an adjustable 
spring partition is disposed below the single-helix twister and the double-helix twister; the shell 
pre-breaking device comprises a shell pre-breaking box, a plurality of squeezing stations are 
provided in the shell pre-breaking box, each of the squeezing stations is provided with a shell 
pre-breaking assembly, the shell pre-breaking assembly comprises a falling U-shaped plate and a 
squeezing U-shaped plate, a first end of the falling U-shaped plate is hinged to the shell 
pre-breaking box, a second end of the falling U-shaped plate is pushed to move by a falling cam, 
the end of the squeezing U-shaped plate opposite to the first end of the falling U-shaped plate is 
pushed to move by a squeezing cam, the end of the squeezing U-shaped plate opposite to the 
second end of the falling U-shaped plate is hinged to the shell pre-breaking box, the squeezing 
cam is in a far rest state when the falling cam moves, and the falling cam is in a far rest state when 
the squeezing cam moves.
Patent WO-2021007618-A1 (WO)
Inventor: KELLY GRAHAM
IPC: A61K39/395
Filed: 2020-07-16
Abstract: A method for improving a response in an individual to immuno-oncology cancer therapy, such as a checkpoint inhibitor, using an isoflavone compound of formula I.
Patent AU-2020203553-A1 (AU)
Title: Neurodegenerative disease treatment
Inventor: GOETZ JUERGEN
IPC: A61N2/00
Filed: 2020-05-29
Abstract: The present invention is directed to methods for treating neurodegenerative diseases and/or improving cognitive function, in particular those associated with protein 5 oligomers, aggregates or deposits, using acoustic energy, such as ultrasound. An example of such a neurodegenerative disease is Alzheimer's disease. The present invention provides a method of improving cognitive function and/or memory in an individual with impaired memory and/or executive function, the method including the steps of identifying a region of the brain of the individual to be treated with acoustic 0 energy, applying a clinically safe level of acoustic energy to the region, thereby saturating or substantially saturating the region with acoustic energy, thereby improving memory in the individual.