baber/WOPTO huggingface dataset:
Patent CA-3064938-A1 (CA)
Title: Pyrazolopyrimidine pde9 inhibitors
Inventor: ARASAPPAN ASHOK
IPC: A61P9/00
Filed: 2018-06-06
Abstract: The present invention is directed to pyrazolopyrimidme compounds which may be useful as therapeutic agents for the treatment of disorders associated with phosphodiesterase 9 (PDE9) The present invention also relates to the use of such compounds for treating cardiovascular and cerebrovascular diseases, such as hypertension, chronic kidney disease and heart failure, and neurological and psychiatric disorders, such as schizophrenia, psychosis or Huntington's disease, and those associated with striatal hypofunction or basal ganglia dysfunction
Patent CA-3066894-A1 (CA)
Inventor: HEIDMANN ODILE
IPC: C07K16/30
Filed: 2018-06-22
Abstract: L'invention concerne la protéine rétrovirale endogène humaine. Cette protéine rétrovirale endogène humaine est généralement désignée par HEMO. L'invention concerne plus particulièrement des formes libérées de la protéine HEMO, plus particulièrement à ces formes libérées, qui sont libérées dans le sang circulant. L'invention concerne également des produits dérivés des formes libérées de HEMO, tels que des anticorps, des vecteurs d'acide nucléique et des cellules modifiées, ainsi que les applications médicales ou biotechnologiques de ces formes libérées ou de produits dérivés, notamment dans les domaines du développement placentaire, de la protection du ftus, du traitement du cancer et de la production de cellules souches.
Patent CA-3068124-A1 (CA)
Title: Casting system
Inventor: HRABINA DAVID
IPC: B22D35/04
Filed: 2018-06-14
Abstract: Provided is a system for casting molten metals. The system includes a mould comprising a casting cavity having an inlet, and a bore between an upper surface of the mould and the inlet. The system further includes a shroud comprising a funnel and a hollow shaft, wherein the funnel is located outside of the mould, adjacent the upper surface, and the hollow shaft is received within the bore and is moveable therein. A lifting mechanism is located on the upper surface of the mould, the lifting mechanism being operable to lift the funnel of the shroud away from the upper surface for bringing the shroud into engagement with a ladle nozzle. Also provided is a method for casting molten metals using the system.
Patent CA-3068305-A1 (CA)
Title: Kinase inhibitors and methods for making and using
Inventor: TAYLOR VANESSA
IPC: C07D405/04
Filed: 2018-06-28
Abstract: Disclosed embodiments concern kinase inhibitors, such as interleukin receptor associated kinases (IRAK) inhibitors, and compositions comprising such inhibitors. Also disclosed are methods of making and using the compounds and compositions. The disclosed compounds and/or compositions may be used to treat or prevent a kinase-associated disease or condition, particularly an IRAK- associated disease or condition.
Patent CA-3069544-A1 (CA)
Title: Compounds and methods for the targeted degradation of androgen receptor
Inventor: CREW ANDREW P
IPC: C07D207/16
Filed: 2018-07-27
Abstract: The present disclosure relates to bifunctional compounds, which find utility to degrade (and inhibit) Androgen Receptor.  In particular, the present invention is directed to compounds, which contain on one end a VHL ligand which binds to the ubiquitin ligase and on the other end a moiety which binds Androgen Receptor such that Androgen Receptor is placed in proximity to the ubiquitin ligase to effect degradation (and inhibition) of Androgen Receptor. The present invention exhibits a broad range of pharmacological activities associated with compounds according to the present invention, consistent with the degradation/inhibition of Androgen Receptor.
Patent CA-3073185-A1 (CA)
Inventor: JONES MITCHELL LAWRENCE
IPC: C07K16/24
Filed: 2018-08-13
Abstract: This disclosure features methods and compositions for treating inflammatory disorders or conditions that arise in a tissue originating from the endoderm using an immune modulator.
Patent CA-3074344-A1 (CA)
Inventor: SPARR CHRISTOF
IPC: C09B11/24
Filed: 2018-08-28
Abstract: The present invention relates to compounds of formula (A), wherein Z is NR10 or O. These compounds represent novel acridinium and xanthylium salts having an unprecedented substituted heterocyclic core. They are useful as fluorescent dyes or precursors thereof in different applications including various imaging and sensing techniques, and, in particular, as photosensitizers and hereby preferably as photocatalysts. The present invention further relates to processes for preparing the inventive compounds via 1,5-organodimetallic reagents from double directed ortho-metalation reactions or combined halogen-metal exchange/ directed ortho-metalation reactions.
Patent CA-3074572-A1 (CA)
Title: Tables chirurgicales
Inventor: CLAYTON MATT
IPC: A61G13/06
Filed: 2018-08-31
Abstract: La présente invention concerne une table chirurgicale comprenant : une base pour reposer sur un sol ; une colonne de hauteur réglable montée sur la base et s'étendant à partir de celle-ci ; un plateau fournissant une surface de support de patient ; un cadre mobile monté entre le plateau et la colonne pour permettre à au moins une partie du plateau de tourner autour d'un axe de tendance, l'axe de tendance s'étendant dans une direction transversale à travers le plateau ; et un mécanisme d'actionneurs accouplé au cadre mobile et conçu pour soulever et abaisser le cadre mobile par rapport à la colonne et pour faire tourner le cadre mobile autour de l'axe de tendance, le mécanisme d'actionneurs comprenant des premier et second actionneurs, le premier actionneur ayant une première extrémité supérieure reliée à une première partie du cadre mobile et une seconde extrémité inférieure accouplée à la colonne et le second actionneur ayant une première extrémité supérieure reliée à une seconde partie du cadre mobile et une seconde extrémité inférieure accouplée à la colonne, les première et seconde parties étant espacées entre elles et situées sur des côtés opposés de l'axe de tendance, les premier et second actionneurs étant chacun inclinés selon un angle aigu respectif dans des directions opposées à partir d'un plan comprenant un axe longitudinal de la colonne et l'axe de tendance de sorte que la première extrémité supérieure de chacun des premier et second actionneurs soit orientée plus loin du plan que la seconde extrémité inférieure respective.
Patent CA-3074890-A1 (CA)
Inventor: FREUNDLIEB JULIA
IPC: A61K9/08
Filed: 2018-09-06
Abstract: The present invention relates to : a method of preparing a stable, copanlisib-containing aqueous bulk solution suitable for lyophilisation and for therapeutic applications; a stable, copanlisib-containing bulk solution, of increased solubility which is directly suitable for lyophilisation; a method of lyophilizing such a copanlisib-containing aqueous bulk solution; a stable, lyophilized, copanlisib-containing solid, in particular powder or cake, particularly containing a therapeutic dose of copanlisib in one or two containers, particularly one sealed container; a method of reconstituting such lyophilisates; and a stable, reconstituted, copanlisib-containing solution of increased solubility, suitable for further dilution and for therapeutic applications.
Patent CA-3075149-A1 (CA)
Inventor: REHDER ERIC M
IPC: H01L31/0304
Filed: 2020-03-11
Abstract: A solar cell includes a portion of a Germanium layer having a first side and a second side. The second side has properties consistent with a grinding and etching operation to thin a Germanium wafer to form the Germanium layer. Edges of the portion of the Germanium layer may have properties consistent with dicing using a diamond-coated saw.  The portion of the Germanium layer may have a thickness of less than 150 micrometers.  Compound semiconductor materials and circuitry are coupled to the first side of the portion of the Germanium layer to define a multijunction solar cell. A fused silica cover glass is coupled to the multijunction solar cell via a silicone-based adhesive.
Patent CA-3076507-A1 (CA)
Inventor: MILO THOMAS
IPC: E04B1/343
Filed: 2020-03-23
Abstract: An inflatable structure that can be easily transported, inflated, assembled, disassembled and stored with minimal if any tools and in a fraction of the time associated with prior art structures. The inflatable structure is comprised of a plurality of interchangeable structural members removably attached to one another, and that afford the user virtually endless design options and superior weatherproofing and insulating qualities. The structural member further comprises a plurality of filaments positioned in an airtight void, wherein said plurality of filaments are in tension when the structural member is inflated.
Patent CA-3079864-A1 (CA)
Inventor: BEASON ROBERT C
IPC: G01S7/02
Filed: 2012-09-07
Abstract: ABRÉGÉ DE LA DIVULGATION Une méthode de surveillance des cibles aériennes est fournie. La méthode implique lutilisation dun appareil radar à la première position de balayage afin de surveiller au moins un sous-volume prioritaire dun volume 3D en temps réel. En outre, la méthode est appliquée simultanément avec le premier appareil radar et un deuxième appareil radar multifonction à deux axes afin de surveiller au moins un sous-volume dun volume 3D. Date Recue/Date Received 2020-04-30
Patent CA-3080224-A1 (CA)
Inventor: Di Benedetto Paul
IPC: A61N1/39
Filed: 2018-10-26
Abstract: A portable emergency or medical package has: a body; a plurality of compartments for housing medical supplies, and a compartment for communication device, providing real time two-way communication between a user of the package and a communication appliance remote from the package, wherein the communication device is detachable from the remainder of the package. A method of delivering a package of emergency or medical supplies to a desired location provides control over the use of the medical supplies by a remote person. At the desired location, a user is instructed to remove the communication device from the package, which enables the provision of real time two-way audio communication between a remote person and the user and at least one way video communication to the remote person, whereby the remote person can provide instructions and directions to the user.
Patent CA-3080883-A1 (CA)
Inventor: KELLY KEVIN
IPC: F25D13/04
Filed: 2017-10-31
Abstract: The present invention includes methods and apparatus for the automated provision of goods through the use of scanning systems. More specifically, the present invention provides a method for automatically conveying which goods are being ordered, where the goods will be picked up, an associated method of payment, kitchen fulfillment, item tracking, and automatic delivery by a dispenser apparatus. In preferred embodiments, the present invention is applied to the automated ordering and pick-up of food items at a fast food restaurant.
Patent CA-3080956-A1 (CA)
Title: Ciment microfin de haute densite pour operations de cimentation sous pression
Inventor: AL-YAMI ABDULLAH
IPC: C04B14/30
Filed: 2018-11-21
Abstract: Un procédé pour effectuer des opérations de cimentation correctives dans un puits souterrain consiste à utiliser une composition de ciment microfin de haute densité, la composition étant constituée d'un ciment microfin, et d'un tétraoxyde de manganèse et ayant une densité comprise entre 145 et 165 pcf. La composition de ciment microfin de haute densité est injectée dans une zone de haute pression du puits souterrain. La composition de ciment microfin de haute densité est pompée dans une zone de faible injectivité du puits souterrain.
Patent CA-3082113-A1 (CA)
Title: Pomme de douche avec portage a distance
Inventor: QUINN MICHAEL J
IPC: B05B3/04
Filed: 2018-11-13
Abstract: Une pomme de douche peut comprendre un premier plénum en communication fluidique avec un premier groupe de buses, un second plénum en communication fluidique avec un second groupe de buses, et un ensemble de direction de l'eau en communication fluidique avec le premier plénum, le second plénum et une entrée de fluide, et raccordant fluidiquement en alternance le premier plénum et le second plénum avec l'entrée de fluide. L'ensemble de direction de l'eau peut comprendre une turbine et un obturateur conçu pour osciller entre des positions, l'oscillation de l'obturateur reliant en alternance de manière fluidique les premier et second plénums avec l'entrée de fluide.
Patent CA-3087436-A1 (CA)
Title: Anode coating compositions and uses thereof
Inventor: ALLAIRE CLAUDE
IPC: C25C3/12
Filed: 2018-09-06
Abstract: The present document describes an aqueous coating composition for preventing or reducing air oxidation of a carbon material, and aqueous priming coating composition for application to a carbon material prior to application of the aqueous coating composition, chemical treatment of a carbon material comprising both the aqueous coating composition and aqueous priming coating composition, and methods of coating carbon material with the compositions.
Patent CA-3088395-A1 (CA)
Title: Non-invasive blood sugar level monitoring apparatus integrated with real-time health support system
Inventor: GOPALAKRISHNAN MURALIDHARAN
IPC: A61B5/1455
Filed: 2019-01-13
Abstract: A non-invasive continuous blood sugar level monitoring apparatus integrated with real-time health support system. The blood sugar levels and other vital physiological information of the user can also be tracked wirelessly through the apparatus. The apparatus has an integrated real-time alert and reminder feature for notifying the user during medication and unusual physiological conditions. An automated diet and lifestyle recommendation solution is integrated into the device to help the user maintain healthy blood sugar and blood pressure levels. The low-powered telemetry device is used for communicating the stored physiological information of the user and the computed results between the network of devices.
Patent CA-3092126-A1 (CA)
Title: Composition aqueuse contenant un sel, de l'acide acetique et des sucres
Inventor: MERKL SUSANNE KERSTIN
IPC: A23L27/10
Filed: 2019-02-04
Abstract: La présente invention concerne une composition aqueuse contenant un sel, de l'acide acétique et des sucres qui peut être utilisée en tant que sauce ou assaisonnement. L'avantage de l'invention est que la croissance de levures et/ou de moisissures dans des produits alimentaires aqueux est réduite, ce qui conduit à une bonne aptitude à la conservation de la composition. Cela a été réalisé au moyen d'un taux de sel relativement faible et sans conservateurs, ce qui rend ce produit très polyvalent : un chef peut l'utiliser librement, sans risque de surdosage du taux de sel d'un plat alimentaire préparé. Enfin, le produit contient des sucres et de l'acide acétique, et a un pH compris entre 3 et 4,6.
Patent CA-3092244-A1 (CA)
Title: Process for manufacturing a submarine power cable and power cable so manufactured
Inventor: POZZATI GIOVANNI
IPC: H01B13/016
Filed: 2020-09-03
Abstract: Process for manufacturing a power cable includes: providing a power cable core having an electric conductor; providing a copper foil; providing a protective strip over the power cable core, the protective strip having a radially inner and outer surface and being made of copper with a coating; folding the copper foil around the power cable core so as to bring two longitudinal copper foil rims to contact one to the other; welding the two contacted longitudinal copper foil rims thus obtaining a copper sheath in form of a tube with a welding seam ; reducing the diameter of the copper sheath to put it into direct contact with the power cable core and the protective strip; heating the protective strip and the copper sheath at a temperature higher than the melting temperature of the coating of the strip so that the coating fuses in the welding seam.
Patent CA-3095329-A1 (CA)
Title: Cerium-stabilized polyamides and processes for making same
Inventor: SPARKS BRADLEY J
IPC: C08L77/00
Filed: 2019-03-29
Abstract: A heat-stabilized polyamide composition comprising from 25 wt% to 90 wt%% of an amide polymer from 0.01 wt% to 10 wt% of a cerium-based heat stabilizer, a second heat stabilizer, a halide additive, and less than 0.3 wt% of a stearate additive. A weight ratio of halide additive to stearate additive is less than 45Ø
Patent CA-3095616-A1 (CA)
Inventor: BAYLON DAVID M
IPC: H04N19/117
Filed: 2019-03-29
Abstract: A system and method for coding video in which deblocking artifacts are reduced by using modified filtering that is based, at least in part on pixel intensity associated with a coding unit, such that filtering levels are increased as pixel intensity increases. In some embodiments, an offset value or indicator of an offset value for parameters associated with deblocking filter parameters can be associated with a filtering level that is based at least in part on an intensity value.
Patent CA-3095985-A1 (CA)
Title: Electrochemical production of hydrogen from sea water
Inventor: HUDSON STEWART
IPC: C25B9/17
Filed: 2019-05-07
Abstract: The invention relates to an apparatus for the electrochemical production of hydrogen gas from salt water, the apparatus comprising at least one cathode; at least one anode spaced apart from the cathode by a defined distance and connectors for electrically connecting the electrodes to a direct current electrical power supply;wherein the cathode comprises a paramagnetic material and the anode comprises a diamagnetic material. The invention also relates to an environmentally-friendly method for the production of hydrogen gas from sea water.
Patent CA-3097736-A1 (CA)
Inventor: BROWN MATTHEW S
IPC: F21V17/00
Filed: 2018-10-29
Abstract: An illumination apparatus includes a light assembly having a housing section and an attachment section. At least one light emitting device is contained within the housing section. The attachment assembly can include a substantially flat base section and an attachment member extending outwardly from the base section. The attachment section of the light assembly can define a recess having a size and shape that is complementary to the attachment member of the attachment assembly, such that the light assembly and the attachment assembly can be releasably attached to each other by complementary frictional engagement of the attachment member of the attachment assembly and the attachment section of the light assembly when the attachment member is positioned within the attachment section.
Patent CA-3097777-A1 (CA)
Title: Procede de refroidissement d'un courant d'alimentation en gaz naturel et de recuperation d'un courant de liquide de gaz naturel a partir du courant d'alimentation en gaz naturel
Inventor: AGBARAKWE UCHENNA MCDONALD
IPC: F25J3/02
Filed: 2019-04-11
Abstract: La présente invention concerne un procédé et un système pour refroidir un courant d'alimentation en gaz naturel et récupérer un courant de liquide de gaz naturel à partir du courant d'alimentation en gaz naturel à l'aide d'une unité de refroidissement à base d'expansion et d'une unité d'élimination de liquide de gaz naturel qui sont intégrées. L'intégration est réalisée en utilisant un courant de refroidissement (ou une partie de celui-ci) provenant de l'unité de refroidissement à base d'expansion pour fournir un service de refroidissement à l'unité d'élimination de liquide de gaz naturel.
Patent CA-3098863-A1 (CA)
Inventor: RODGERS TRAFTON D
IPC: A61B5/01
Filed: 2019-05-02
Abstract: Toilets and accessories associated with toilets are provided. According to various implementations, an exemplary toilet includes a base configured to be fastened to a floor and a pair of bracket panels, which are connected to the base and extend upward from the floor in a vertical direction. The exemplary toilet also includes a tank housing confined between the pair of bracket panels. The tank housing has an adjustable height above the base such that the tank housing can move in the vertical direction between a raised position and a lowered position. The exemplary toilet also includes a bowl attached to the tank housing, wherein the bowl is configured to support the weight of a user.
Patent CA-3099854-A1 (CA)
Inventor: GABBAY DANIEL
IPC: A47C21/06
Filed: 2018-05-18
Abstract: An apparatus for lifting a mattress to an optimal work level so as to facilitate the bed making process. More specifically an apparatus for lifting a mattress, the apparatus including a generally rectangular ring shaped inflatable member with a generally constant cross section configured to be disposed between a mattress and a supporting structure of a bed in an unsecured manner; an air pump in fluid communication with the inflatable member, the air pump configured to inflate the inflatable member to a substantially uniform pressure throughout an entire perimeter of the inflatable member; a power supply in electrical communication with the air pump for providing power to operate the air pump; a switch in electrical communication between the power supply and the air pump configured for activating and deactivating the air pump; and a valve configured to control both inflation and deflation of the inflatable member.
Patent CA-3099893-A1 (CA)
Title: Compositions et methodes pour le traitement du cancer
Inventor: CHANTEUX STEPHANIE
IPC: A61P35/00
Filed: 2019-06-17
Abstract: La présente invention concerne des composés de liaison à l'antigène qui inhibent l'activité enzymatique de CD39 humaine soluble. L'invention concerne également des cellules produisant ces composés ; des procédés de fabrication de ces composés, ainsi que des anticorps, des fragments, des variants et des dérivés de ceux-ci ; des compositions pharmaceutiques les contenant ; des procédés d'utilisation de ces composés pour diagnostiquer, traiter ou prévenir des maladies, par exemple le cancer.
Patent CA-3102892-A1 (CA)
Inventor: HOGERS RENE CORNELIS JOSEPHUS
IPC: C12Q1/6834
Filed: 2019-06-12
Abstract: The invention concerns a method for the production of oligonucleotides. The method of the invention uses a combination of amplification, restriction and affinity purification to produce high quality oligonucleotides. The invention further pertains to a nucleic acid precursor for use in the method of the invention, a solid support comprising said nucleic acid precursor and a kit for use in the method of the invention.
Patent CA-3103068-A1 (CA)
Title: Triazolotriazine derivatives as a2a receptor antagonists
Inventor: SUN SANXING
IPC: A61K31/53
Filed: 2018-06-26
Abstract: The present invention provides triazolotriazine derivatives of formula (1) as A2A receptor antagonists. Compounds of formula (1) and pharmaceutical compositions including the compounds can be used for the treatment of disorders related to A2A receptor hyperfunctioning, such as certain types cancers. Compounds of formula (1) and methods of preparing the compounds are disclosed in the invention.
Patent CA-3104332-A1 (CA)
Inventor: LINDLEY TIMOTHY
IPC: B65G1/137
Filed: 2019-06-19
Abstract: The invention relates to a picking method for picking at least one order good (26a) into or onto a target loading aid (30), wherein, on the basis of a transfer request, goods (21a..21e) stored in a first storage area (8) by means of first loading aids (27a..27c) are transferred from a first loading aid (27a..27c) into or onto at least one second loading aid (29a..29c) and deposited in a second storage area (16). When a picking order is received, an order good (26a) is retrieved from the second storage area (16) and loaded into or onto the target loading aid (30). In the execution of the transfer request, the first loading aid (27a..27c) is completely or partially unloaded, depending on whether a parameter associated with a goods type reaches a threshold value. The invention further relates to a storage and picking system (1) for carrying out said method.