baber/WOPTO huggingface dataset:
Patent CA-2044124-A1 (CA)
Title: Benzimadazol derivatives, the process for their preparation, the new intermediates obtained, their applicaiton as drugs and the pharmaceutical composition containing such
Inventor: FORTIN MICHEL
IPC: C07C233/40
Filed: 1991-06-07
Abstract: The invention relates to the products: <IMAGE>  in which:     R represents an alkyl or alkenyl,   either R1B, R2B, R3B and R5B represent hydrogen, or one of R2B and R5B represents hydrogen or -CH2-O-R10, R10 represents hydrogen, alkyl or alkenyl or <IMAGE> and one of R1B and R3B represents halogen and the other -OR6, -CO2R7 or -R11, in which:     R6 and R7 represent hydrogen, alkyl or alkenyl,   R11 is:     a) optionally substituted alkyl,   b) alkenyl,   c) acyl or formyl,   d): <IMAGE>     or one of R1B, R2B, R3B and R5B represents hydrogen and the others are -CH2-O-R10, -OR6, -CO2R7, -R11 or <IMAGE>, R4B represents carboxyl, free, esterified or salified, or tetrazolyl,  or -(CH2)m-SO2-X-R12, m representing 0 to 4 and     either (-X-R12) represents NH2 or X represents a bond or -NH-, -NH-CO-NH- or -NH-CO- and R12 represents alkyl, alkenyl or aryl,   products (IB) being in all the possible isomeric forms, as well as the salts, to a process for their preparation and to their use as medicaments.
Patent CA-2044673-A1 (CA)
Title: Method of diuretic treatment with 3,7-diazabicyclo[3,3,1] nonane compounds and pharmaceutical compositions therefor
Inventor: BUROW KURT
IPC: A61K31/439
Filed: 1991-06-14
Abstract: Abstract of the Disclosure A method of treating a mammal in need of diuretic treatment by administering an effective diuretic amount of a diuretically active 3,7,9,9-tetrasubstituted 3,7-diazabicyclo[3,3,1]nonane compound, diuretic pharmaceutical compositions containing an effective diuretic amount of a diuretically active 3,7,9,9-tetrasubstituted 3,7-diazabicyclo[3,3,1]nonane compound; and previously unknown diuretically active 3,7,9,9-tetrasubstituted 3,7-diazabicyclo[3,3,1]nonane compounds containing an optionally substituted phenylalkyl group in the 3-position.
Patent CA-2045110-A1 (CA)
Title: Method and apparatus for casting engine block
Inventor: DANNOURA SADAYUKI
IPC: B22D19/00
Filed: 1991-06-20
Abstract: In a method and apparatus for casting an engine block, a core holding portion located below an open upper mold located above a lower mold fixed on a stationary platen is caused to hold a water jacket formation destructive core surrounding a cylinder bore formation portion.  Slide molds divided in a circumferential direction, located between the upper mold and the lower mold, and supported by the upper mold to be opened/closed in a horizontal direction is closed.          Mold clamping is performed upon downward movement of the upper mold.  A molten metal is injected at a high casting pressure of not less than 300 kg/cm2 from a molten metal injection sleeve open to a portion at which the lower mold is brought into direct contact with the upper mold.
Patent CA-2046378-A1 (CA)
Inventor: VAN DER VEEN ALBERTUS C
IPC: H03J7/06
Filed: 1991-07-05
Abstract: ABSTRACT     The invention concerns a radio receiving system designed to receive selectively signals from a series of transmitters transmitting at frequencies each in a very narrow frequency band and each separated from the other transmitters by only a small increment of frequency.  Such receiving systems are useful for picking up signals from transmitters carried by falcons or other hunting birds.   The system comprises a receiving circuit (12), a memory (22, 24) programmed with data  representing a  set of  receiving channels at predetermined frequencies,  preferably around   216  MHz, selector means  (26) for selecting a channel of the set, tuning means  (20, 23) for fine tuning the frequency of a selected channel, electrically programmable memory means (22, 25) for recording fine tuning data relating to each channel, adjusted frequency signal generating means  (17)  for generating an adjusted frequency signal dependent on the preprogrammed data and the fine tuning data relating to each channel when that channel is selected by the selecting means, and means (15, 16) for using the adjusted frequency signal to control the receiving circuit.
Patent CA-2048134-A1 (CA)
Inventor: MANNL REINHARD
IPC: C03B23/045
Filed: 1991-07-30
Abstract: ABSTRACT OF THE DISCLOSURE    Chucks for glass tubes should be designed so that, on the one hand, they grasp the glass tube gently so that the tube is not destroyed, and, on the other hand, so that they hold it securely enough so that a proper processing of the glass tube is possible.  This causes a degree of technical complexity which enlarges the dimensions of the chuck and leads to a narrow diameter range for the clampable glass tubes.  For other diameter ranges, the chucks have to be changed.  The chuck according to the invention has a wide diameter range with small outside dimensions.  The chuck has clamping jaws which can be moved radially with respect to its longitudinal axis and has a distance from the longitudinal axis determined by a pressure sleeve, which is connected to the clamping jaws by a forced guidance device.  The forced guidance forms an angle of 30° to 60°, and preferably 45°, with respect to the longitudinal axis.  The chuck is used to hold glass tubes in a machine for producing vials.
Patent CA-2048766-A1 (CA)
Inventor: ZIBELL STEVEN E
IPC: A23L27/30
Filed: 1991-08-08
Abstract: A method of making zein coated, high-potency sweeteners or other gum ingredients that does not use alcohol is disclosed.  A solution of zein and water at a pH of between about 11.5 and about 12.1 is prepared, containing between about 1% and about 25% by weight zein, and the aqueous zein solution is combined with a high-potency sweetener or other gum ingredients to form a zein-coated ingredient.  The zein coated ingredient is then used to make chewing gum.  Preferable coating steps include spray drying and fluid bed coating.
Patent CA-2049171-A1 (CA)
Title: Surface coating material for tundish and steel ladle
Inventor: TANIGUCHI TERUHIKO
IPC: B22D41/02
Filed: 1991-08-14
Abstract: REFRACTORY MATERIAL CONTAINING CALCIUM CARBONATE-STABILIZED SYNTHETIC DOLOMITE          Abstract A refractory material containing a synthetic dolomite aggregate having a calciumcarbonate coating on the surface thereof and further containing magnesia, a binder, a plasticizer, an organic fiber homogenizer, a bond stabilizer, and a dispersant; and a method of forming a protective refractory surface on the lining of a tundish, steel ladle and the like by spraying, gunning or troweling the surface coated aggregate containing refractory material thereon are disclosed. This material offers the multiple advantages of improving resistance to slaking, reducing alumina inclusions in the steel, and reducing clogging of the tundish nozzle.
Patent CA-2049680-A1 (CA)
Title: Reconfigurable rf matching circuit
Inventor: NEWBERG IRWIN L
IPC: H04B10/12
Filed: 1991-08-22
Abstract: RECONFIGURABLE RF MATCHING CIRCUIT                  ABSTRACT OF THE DISCLOSURE     An RF fiber optic link that includes a laser diode transmitter,  a photodiode detector receiver, a means of optically connecting the transmitter and receiver,  and respective reconfigurable active RF matching circuits for the laser input and the photodiode output.  Reconfiguration of the active RF matching circuits is achieved by electri-cal or optical control signals.
Patent CA-2051034-A1 (CA)
Title: Pharmaceutical formulation containing a benzoyl urea derivative
Inventor: VAN LAAR BEN
IPC: A61P35/00
Filed: 1991-09-10
Abstract: ABSTRACT            The invention is concerned with an pharmaceutical formula-tion containing a benzoyl urea derivative according to the formula l                         (1) in which: - X is an oxygen or a sulfur-atom; - Rl is a hydrogen atom, a group (O-A)n, wherein A re-presents a hydrogen atom, an alkanoyl group having l to 6 carbon atoms, a carbamoyl group optionally substituted by alkyl containing 1 to 6 carbon atoms or by phenyl, a benzylcarbonyl group optionally substituted by halogen, a benzoyl group,  a benzyl group,  an aryloxycarbonyl group optionally substituted by halogen, or an alkoxy-carbonyl-alkyl  group containing  from  l  to  6  carbon atoms, or Rl is an alkylmercapto group, having l to 3 carbon atoms or a group -S-A, wherein A has the above given meaning; - R2 is a hydrogen or halogen atom, an alkyl group having 1 to 6 carbon atoms optionally substituted by halogen, or R2 is a nitro group; - R3 is a hydroyen or halogen atom, a nitro group, a 1 to 6 carbon atoms containing alkyl group optionally substi-tuted by halogen, an alkoxy group containing 1 to 6 carbon  atoms  optionally  substituted  by  halogen,  a cycloalkyl group, containing 5-l0 carbon atoms, option-ally substituted by alkyl  groups having  1-3  carbon atoms, an alkanoyl group containing from 1 to 6 carbon atoms, a benzoyl group, a nitrile group, an amino group optionally substituted by 1 or 2 alkyl groups having 1 to 3 carbon atoms, an alkoxycarbonyl group containing from 1 to 6 carbon atoms, or a piperidinocarbonyl group; - R4 is a hydrogen atom, a group (O-A)m or S-A, wherein A   has the above given meaning, or an alkylmercapto group wherein the alkyl group contains from 1 to 3 carbon akoms; - R5 is a hydrogen atom, or represents from 1 to 3 halogen atoms; - n and m are integers, whereas the sum n+m has the value from 1 to 6, together with an ionic surface-active compound.
Patent CA-2051652-A1 (CA)
Title: Mercapto-acylamino acids
Inventor: SMITH ELIZABETH M
IPC: A61K38/55
Filed: 1990-04-06
Abstract: Novel mercapto-acylamino acids of the formula (I), wherein Q is hydrogen or R7CO-; R1 is lower alkyl, cyclolower alkyl, aryl or heteroaryl;  R2 is hydrogen; lower alkyl; cyclolower alkyl;  lower alkyl substituted with hydroxy, lower alkoxy, mercapto, lower alkylthio, aryl or heteroaryl; aryl; or heteroaryl; R3 is -OR5 or -NR5R6; R4 and R9 are independently -(CH2)qR8, provided that when R4 and R9 are both hydrogen, R2 is biphenylyl, phenoxyphenyl, phenylthiophenyl, naphthyl, heteroaryl, or lower alkyl substituted with hydroxy, lower alkoxy, mercapto or lower alkylthio; R5 and R6 are independently selected from the group consisting of hydrogen, lower alkyl, hydroxy lower alkyl, lower alkoxy, lower alkyl and aryl lower alkyl, or R5 and R6 together with the nitrogen to which they are attached form a 5-7 membered ring; R7 is hydrogen, lower alkyl or aryl; R8 is hydrogen, hydroxy, lower alkoxy, mercapto, lower alkylthio, aryl or heteroaryl; n is 1 or 2; p is 0 or 1; q is 0,1 or 2; and t is 0 or 1; and the pharmaceutically acceptable salts thereof useful in the treatment of cardiovascular disorders and pain conditions and combinations of mercapto-acylamino acids and atrial natriuretic factors or angiotensin converting enzyme inhibitors useful for treating cardiovascular disorders are disclosed.
Patent CA-2052039-A1 (CA)
Inventor: VILLAR ANTHONY F
IPC: A43B3/00
Filed: 1991-09-23
Abstract: Novel footwear upon the upper front portion of which an animated face with movable eyes is located.  The footwear comprises an inner sole, an outer sole, and an upper shoe surface affixed together in a wearable relationship, with an arch-shaped support member located in a forward interior portion of the footwear.  The upper portion of the arch is in contact with the interior of the upper shoe surface, and its opposite lower edges are affixed to edge portions of the outer sole.  The inner sole is interrupted at a forward  location  generally corresponding to the location of the arch, and an upwardly biased treadle member  is operatively  disposed  at  such interrupted location.  Upon the forward part of the foot of the user, on occasion, entering such arch member and extending therethrough, the ball of the foot normally rests on the treadle.  The upper central portion of the arch serves as support for simulated eye members that are displayed on the exterior of the upper shoe surface, which eye members are pivotally mounted in spaced apart locations on the arch member, and have normal as well as deflected positions.  Linkage means interconnect the eye members and the treadle, such that the eye members are rotated each time the foot of the user presses down on the treadle member.  The eyes are biased to rotate back to their normal positions when the user's weight is removed from the treadle.
Patent CA-2062037-A1 (CA)
Title: Adjustable book rest
Inventor: SHEREMETTA BEVERLEY
IPC: A47B23/04
Filed: 1992-02-28
Abstract: A readily adjustable and portable book rest includes a support member having a transversely extending fold line providing an upper support member portion above the fold line and a lower support member portion below the fold line. A rigid spine is secured to the upper support member portion and projects therefrom below the fold line, and a flexible adjustment strap extending from the lower support member portion is securable to the spine at different positions therealong to enable the book rest to be erected for use with the upper support member portion at a desired angle. The lower support member portion is angulated about the fold line rearwardly relative to the upper support member portion and the adjustment strap is appropriately secured to the spine to cause the desired angle to be maintained by the book rest when set down on a supporting surface with a lower edge of the lower support member portion and a lower end of the spine being supported thereby.
Patent CA-2064350-A1 (CA)
Title: Perforated trapezoidal-shaped fill bar splash type water cooling towers
Inventor: KINNEY OHLER L JR
IPC: F28F25/08
Filed: 1992-03-23
Abstract: ABSTRACT OF THE DISCLOSURE An improved splash-type fill bar (32) for water cooling towers (10) is provided which gives enhanced water cooling as compared with conventional bars.  The bars (32) are  of  trapezoidal  configuration  and  present  a  flat, apertured top wall  (36),  a pair of obliquely oriented, downwardly and outwardly extending apertured sidewalls (42, 44) and short, horizontal, imperforate flange walls (50, 52)  extending from the  lower margins  (46,  48)  of the sidewalls (42, 44).  The width of top wall (36) is at least four times the vertical height of a sidewall (42, 44) so as to  present an  effective  water  dispersal  surface;  the oblique sidewalls  (42,  44)  and  flange walls  (50,  52) prevent formation of gravitating sheets or films of water which can inhibit tower performance.
Patent CA-2065240-A1 (CA)
Inventor: SLATER CHARLES R
IPC: A61B19/00
Filed: 1991-05-07
Abstract: A biological forceps device (10), comprising a flexible main coil (50) attached at its distal end (12) to a pair of homologous jaws (18). The jaws (18) are opened and closed by attachment to a pair of pull wires (60) which extend through the main coil (50), into a handle (17) at its proximal end (16). The handle (17) has a spool (19) which slides about a central shaft (56) attached to the main coil (50).
Patent CA-2068224-A1 (CA)
Title: Novel potent inducers of terminal differentiation and method of use thereof
Inventor: MARKS PAUL A
IPC: C07C243/24
Filed: 1990-11-14
Abstract: The invention provides compounds, several of which belong to a class having two or more nonpolar components connected by a polar group and having polar groups on the termini of the compound. The invention also concents a method of selectively inducing termini differentiation of neoplastic cells and thereby inhibiting proliferation of such cells which comprises contacting the cells under suitable condition with an amount of the compound effective to selectively induce terminal differentiation. Moreover, the invention provides a method of treating a patient having a tumor characterized by proliferation of neoplastic cells which comprises administering to the patient an amount of the compound effective to selectively induce terminal differentiation of such neoplastic cells, thereby inhibiting their proliferation and suppressing oncogenicity. Lastly, the present invention provides a pharmaceutical composition comprising a pharmaceutically acceptable carrier and the compound in an amount effective less than an amount which would cause toxicity in the patient.
Patent CA-2070253-A1 (CA)
Inventor: NIEDERHAUSER WERNER
IPC: A61M25/10
Filed: 1992-06-02
Abstract: A catheter system for mechanical dilatation of coronary stenoses in particular, with a balloon dilatation catheter, a controllable guide wire and a guide catheter, the balloon dilatation catheter having, for the perfusion of vessel fluid during dilatation, side openings arranged distal and proxi-mal of the balloon and connected to one another via a lumen extending within the balloon. An outlet opening is provided proximal of the balloon and an end hole for the guide wire is provided distal of the balloon. Proximal of the outlet opening, a shaft of the balloon dilatation catheter is designed with two lumina, a first lumen being provided for a pressure fluid for widening the balloon, and the second lumen being provided for receiving the guide wire or a temporary strengthening wire and for flushing the side openings with, for example, heparin.
Patent CA-2070503-A1 (CA)
Inventor: BELAGAJE RAMA M
IPC: C07K19/00
Filed: 1992-06-04
Abstract: The instant invention provides novel molecules derived from the components of proinsulin using recombinant DNA technology. The invention provides molecules of the formula A-C-B wherein A is the A-chain of an insulin species, B is the B-chain of an insulin species and C is a connecting peptide. These molecules possess insulin-like activity and are useful for the treatment of diabetes mellitus, particularly non-insulin dependent diabetes mellitus. These molecules are also useful for the production of insulin and constitute a novel pathway for the recombinant production of insulin species. The invention provides a method of making insulin proceeding through the compounds of the invention as intermediates. The instant invention further provides recombinant DNA compounds which encode the compounds of the invention. <IMAGE>
Patent CA-2071551-A1 (CA)
Inventor: RABE DUANE C
IPC: H04L27/22
Filed: 1991-12-18
Abstract: A radio receiver having at least two operational states and including a variable gain amplifier and at least two adaptive DC offset compensators (421, 427) to suppress undesired DC offset.    The first operational state of the radio receiver (121 ) adjusts the adaptive DC offset compensator circuits (421, 427) to appropriate output levels in absence of an input signal to the radio receiver (121).    The second operational state receives the input signal through the radio receiver (121) and eliminates the undesired DC offset (309) from the received input signal with the adaptive DC offset compensator circuits (421, 427) and allows the received input signals to be processed.
Patent CA-2072656-A1 (CA)
Title: Transgenic plants having a modified carbohydrate content
Inventor: VAN OOYEN ALBERT J J
IPC: C12N15/56
Filed: 1991-09-13
Abstract: The present invention provides plants with a modified taste, solids content and/or texture. The invention also provides methods of obtaining such plants via transformation with DNA constructs containing genes encoding enzymes capable of degrading plant polysaccharides and optionally additional genes encoding enzymes which are capable of further modifying the degradation products resulting from the first degradation step.
Patent CA-2072692-A1 (CA)
Title: Fluid flow controller
Inventor: YAMAJI MICHIO
IPC: F16K41/12
Filed: 1992-06-29
Abstract: A fluid-controller comprises a body (1) provided  with a recessed valve chamber 12 communicating with a fluid inlet port (10) and  a  fluid  outlet  port  (11)  and having a valve seat (13) formed at the bottom thereof, a diaphragm (2) disposed  above  the  valve  seat  for keeping the valve chamber (12) airtight, the diaphragm being adapted to directly contact the valve seat (13) by  moving  the  central portion thereof in a vertical direction or indirectly contacting the valve  seat  13 through  the  disc 6, and a stem 8 elevatably disposed above the  diaphragm  (2)  for  lowering  the  central portion of the diaphragm 2, wherein a stop mechanism 3 is  interposed  between  the   body   (1)   near   the circumferential  edge  of  said  diaphragm (2) and the lower end of the stem (8) for  limiting  the  downward movement  of the stem (8) when the fluid controller is in a fully closed position.
Patent CA-2075419-A1 (CA)
Title: Anatomically conformal quadrature mri surface coil
Inventor: MISIC GEORGE J
IPC: A61B5/055
Filed: 1992-08-06
Abstract: ABSTRACT OF THE DISCLOSURE       A quadrature surface probe comprising two individual mirror image coil loops arranged so that the magnetic field vectors of the respective coil loops are substantially perpendicular.  An area of overlap between the first and second coil loops is adjusted to minimize the mutual coupling between the individual coils.  Also disclosed is the method of manufacturing the quadrature surface probe.
Patent CA-2076273-A1 (CA)
Inventor: SMITH W NOVIS JR
IPC: C09D127/16
Filed: 1992-08-17
Abstract: ABSTRACT OF THE DISCLOSURE    A method for forming a seal or coating with a composition comprising polyvinylidene difluoride and an aqueous emulsion of acrylates, methacrylates, an unsaturated carboxylic acid and/or acrylamide and a solvent having a low boiling point.   The composition can be used to form a protective coating on parts or to form seals with joints or to form a bandage on mammals.
Patent CA-2078146-A1 (CA)
Title: Process for producing metals and metal alloys in a smelt reduction vessel
Inventor: KEOGH JOHN V
IPC: C21B13/14
Filed: 1991-03-13
Abstract: A process and a smelt reduction vessel (1) for producing metals and metal alloys, in particular iron and iron alloys, from metal oxides and ores in a smelt reduction vessel. The process and the vessel are characterised in that loss of liquid and solids with waste gases (11) from the vessel are minimised by causing the waste gases, oxidising gases (5) and entrained liquid and sol-ids in the space in the vessel that is above the molten metal to rotate about a vertical axis of the vessel thereby forcing liquid and solids outwardly toward the wall of the vessel. This rotational motion may be caused by injecting some or all of the oxidising gases through tuyeres (4) positioned above the bath surface obliquely to a vertical plane through a vertical axis of the vessel. The vessel may have a substantially rotationally symmetrical shape at least in the space above the molten metal (2A).
Patent CA-2080205-A1 (CA)
Title: Arrangement for converting a multi-row stream of containers into a single-row stream of containers
Inventor: ELSNER PAUL
IPC: B65G43/00
Filed: 1992-10-08
Abstract: TITLE OF THE INVENTION:  ARRANGEMENT FOR CONVERTING A MULTI-ROW STREAM OF  CONTAINERS INTO A SINGLE-ROW STREAM OF CONTAINERS          ABSTRACT OF THE DISCLOSURE:    An arrangement for converting a multi-row stream of containers into a single-row stream of containers where there is provided between a feed mechanism for the multi-row stream and a withdrawal mechanism for the single-row stream an intermediate conveyor mechanism that comprises a plurality of conveyor belts that are operated at progressive speeds (speed staging).   To convert the multi-row stream of containers,  the intermediate conveyor mechanism forms  a lane that in the conveying direction narrows symmetrically relative to the central axis of the intermediate conveyor mechanism in  a  funnel-like manner until  it  achieves  a conveying width that corresponds to the single-row stream of containers that is to be withdrawn.          Adjoining the outlet region of the intermediate conveyor mechanism is the withdrawal mechanism, which at least at this outlet region is symmetrical to the central axis and furthermore has a conveying width that corresponds to the single-row stream of containers.   The intermediate conveyor mechanism has more than two speed stages in the conveying direction.