baber/WOPTO huggingface dataset:
Patent NZ-561081-A (NZ)
Title: Manufacture of membranes for desalination and filtration
Inventor: GRAHAM WILLIAM
IPC: B01D69/06
Filed: 2006-03-06
Abstract: A spiral wound membrane which comprises an elongate web of a material which allows water to pass through but inhibits the passage of solids and/or dissolved solids and which has been folded to zig-zag form to produce a stack of layers 68.1 68.2 etc joined to one another by reverse bends 72 74, a perforated tube, the ends of the web forming the stack being secured to the tube, the stack being wound around the tube, there being spacers 58 62 between the layers, the spacers 58 62 holding the layers apart to form water flow passages, alternate water flow passages having the ends thereof transverse to the bends 72 74 sealed closed, the alternate passages being closed by reverse bends 74 at the radially outer ends thereof and being in communication with the perforations of the tube at the radially inner ends thereof.
Patent NZ-562307-A (NZ)
Title: Bio-diesel fuel production and apparatus thereof
Inventor: CHOU CHIH-CHUNG
IPC: C10L/
Filed: 2005-09-20
Abstract: A system for generating an alkyl ester that is suitable for use as a fuel is disclosed wherein the system comprises: a first subsystem including a first reactor having a first inlet to receive a first mixture comprising a first reactant, a second reactant, and an inert solvent to dissolve the first and second reactants, a first enzyme to facilitate a reaction between the first and second reactants to generate a reaction product, and a first outlet to output the reaction product, the inert solvent, and other components;and a second subsystem including a second reactor having a second inlet to receive a second mixture comprising additional second reactant, an inert solvent, at least a portion of the reaction product, and the other components from the first outlet, a second enzyme to facilitate a reaction between the second reactant and the other components to generate more reaction product, and a second outlet to output the reaction product, including the reaction product received at the inlet of the second inlet and the reaction product generated from the reaction between second reactant and the other components.
Patent NZ-569331-A (NZ)
Title: COP 1 for treatment of inflammatory bowel diseases
Inventor: AHARONI RINA
IPC: A61K/
Filed: 2004-01-20
Abstract: Provided is the use of Copolymer 1 for the preparation of a pharmaceutical composition for inhibiting weight loss, inducing weight regain or reducing macroscopic colonic 5 damage by at least 2.2 fold in a subject afflicted with mild to moderate Crohn's disease. The composition can be for oral administration or for injection. (62) Divided Out of 541376
Patent NZ-569731-A (NZ)
Title: N-phenyl-2-pyrimidine-amine derivatives
Inventor: LOISELEUR OLIVIER
IPC: C07D295/12
Filed: 2003-02-06
Abstract: Disclosed is a process for the preparation of an amide of formula IV, wherein: R1, R2, R4 and R5 are all hydrogen, R3 is (4-methyl-piperazinyl)-methyl, R6', is 4-(3-pyridyl)-2-pyrimidinamino, R7' is methyl and R8, is hydrogen, or a pharmaceutically acceptable salt or crystal form thereof, by reacting the amide of formula I, wherein: R1 to R5 are as defined above, R6 is -NHC(NH)NH2 , R7 is methyl and R8 is hydrogen; with a compound of formula VI, wherein R10 is 3-pyridyl and R11 is hydrogen or lower alkyl. (62) Divided Out of 552636
Patent NZ-572798-A (NZ)
Title: Process for the production of safinamide and ralfinamide
Inventor: RUFFILLI TIZIANO
IPC: C07C231/00
Filed: 2007-06-08
Abstract: Disclosed is a process for producing high purity degree (S)-2-[4-(3-fluorobenzyloxy)benzylamino]propanamide (safinamide) of formula (Ia) or (S)-2-[4-(2-fluorobenzyloxy)benzylamino]propanamide (ralfinamide) of formula (Ib) or their salts with a pharmaceutically acceptable acid, characterized in that a Schiff base intermediate respectively of formula (VIa) or (VIb) is submitted to catalytic hydrogenation with hydrogen gas in the presence of a heterogeneous catalyst in a protic organic solvent (such as methanol, ethanol or isopropanol); wherein safinamide or ralfinamide as obtained in their free base form, is optionally converted into a salt thereof with a pharmaceutically acceptable acid. Further disclosed is a pharmaceutical formulation which comprises safinamide, ralfinamide or a salt thereof when prepared by the above process for the treatment of epilepsy, Parkinson's disease, Alzheimer's disease, depression, restless leg syndrome, pain conditions including chronic and neuropathic pain, migraine, bipolar disorders, depressions, cardiovascular, inflammatory, urogenital, metabolic or gastrointestinal disorders.
Patent NZ-576796-A (NZ)
Title: A method of preparing a food grade thermophilic arabinose isomerase by expressing it in corynebacterium or bacillus
Inventor: KIM SEONG-BO
IPC: C12N9/90
Filed: 2007-11-22
Abstract: Disclosed is a method of preparing a food grade thermophilic arabinose isomerase including the steps of: preparing a recombinant vector by inserting a gene encoding thermophilic arabinose isomerase originating from the Geobacillus stearothermophilus DSM 22, into the shuttle vector pCJ-1 (KCCM 10611P) or pHT0l (PBS00l), and producing the thermophilic arabinose isomerase from Corynebacterium or Bacillus which is transfected with the recombinant vector.
Patent NZ-579419-A (NZ)
Title: Albumin-fused kunitz domain peptides
Inventor: HAUSER HANS-PETER
IPC: A61K48/00
Filed: 2003-02-07
Abstract: Provided is an albumin fusion protein comprising a DX-1000 Kunitz domain peptide or a functional fragment or variant thereof, and albumin, or a fragment or variant thereof. The fusion protein extends the half-life in vivo of the DX-1000, which is useful in inhibiting serine proteases. (62) Divided Out of 534492
Patent NZ-588069-A (NZ)
Title: Hydroxamate-based inhibitors of deacetylases b
Inventor: SHULTZ MICHAEL
IPC: A61K31/4025
Filed: 2009-03-24
Abstract: Disclosed are hydroxamate-based compounds represented by general formula (I). An example of a compound of formula (I) is (E)-N-hydroxy-3-(4-{ 1-[2-(2-methyl-1H-indol-3-yl)-ethyl]-pyrrolidin-2-yl} -phenyl)-acrylamide. The compounds are used to treat diseases mediated by histone deacetylase such as cancer, a tumor, a fibrosis, a neoplasia, psoriasis, prostate hyperplasia, Alzheimer's disease, Huntington's disease, Rubenstein-Taybis syndrome, Parkinson's disease, muscular dystrophy, heart failure, cardiac hypertrophy, thrombosis, spinal muscular atrophy, stroke, Rett's syndrome, Lupus, scleroderma, atherosclerosis, and arthritis or an arthritic condition.
Patent NZ-589965-A (NZ)
Title: Heat-curable adhesive composition comprising an alkoxysilane-polyether component, a tackifying resin component and a curing catalyst
Inventor: LAFERTE OLIVIER
IPC: C09J7/22
Filed: 2010-12-15
Abstract: Disclosed is a heat-curable adhesive composition which comprises: a) from 20 to 85% (w/w) of a polyether (A) comprising two hydrolysable alkoxysilanetype end groups; b) from 15 to 80% (w/w) of a compatible tackifying resin; and c) from 0.01 to 3% (w/w) of a curing catalyst (C); wherein component (A) has general formula (I) in which R1 and R2, which are identical or different, each represent a linear or branched alkyl; R3 represents a linear alkylene divalent radical comprising from 1 to 6 carbon atoms; R4 represents a linear or branched alkylene divalent radical comprising from 1 to 4 carbon atoms; n is an integer such that the number-average molecular weight Mn of the polymer of formula (I) is between 20 kDa and 40 kDa; p is an integer equal to 0, 1 or 2; wherein polymers of formula (I) of can conveniently be prepared for example by reactions of alkylene glycols with compounds such as isocyantopropyltrimethoxysilane; and wherein the tackifying resin component (B), has a number average molecular weight between 200 Da and 10 kDa; and is selected from (i) resins obtained by polymerization of terpene hydrocarbons and phenols, in the presence of Friedel-Crafts catalysts; (ii) resins obtained by a process comprising the polymerization of á-methylstyrene; (iii) natural or modified rosins, and their derivatives that are hydrogenated, dimerized, polymerized or esterified by monoalcohols or polyols; (iv) resins obtained by hydrogenation, polymerization or copolymerization of mixtures of unsaturated aliphatic hydrocarbons having around 5, 9 or 10 carbon atoms derived from petroleum fractions; (v) terpene resins; (vi) copolymers based on natural terpenes; and (vii) acrylic resins.
Patent NZ-591165-A (NZ)
Title: Desulphurization process using ammonium hydroxide to remove sulfur contaminants from coal
Inventor: BRUSO BRUCE L
IPC: C10L5/00
Filed: 2009-07-14
Abstract: A method of processing coal to remove contaminants is disclosed, which comprises the steps of:providing a solution of aqueous ammonia (NH4OH ammonium hydroxide) in a selected concentration range of ammonia in a reaction vessel; adding coal into the reaction vessel;agitating the coal inside the reaction vessel to mix the coal and solution to cause the solution to be brought into contact with the surfaces and pores of the coal;discharging the processed coal from the vessel; monitoring the process to detect when the concentration of aqueous ammonia in the reaction vessel has fallen below the selected range; and feeding aqueous ammonia solution with an ammonia concentration in or above the selected range to the reaction vessel to return the solution to within the selected range.
Patent NZ-591955-A (NZ)
Title: Trans-clomiphene for diabetes mellitus type 2
Inventor: VAN AS ANDRE
IPC: A61P3/00
Filed: 2008-09-05
Abstract: Use of a composition comprising 0 percent to about 29 percent w/w of cis-clomiphene and about 100 percent to about 71 percent trans-clomiphene or a salt or analog thereof in the manufacture of a medicament for treating diabetes mellitus type 2 in a subject with secondary hypogonadism.
Patent NZ-593294-A (NZ)
Title: Measuring g protein coupled receptor activation
Inventor: TROWELL STEPHEN CHARLES
IPC: C07K14/705
Filed: 2010-01-28
Abstract: 593294 Disclosed is a method of detecting a compound, the method comprising, i) contacting a sample with a cell-free composition comprising a) at least one G protein coupled receptor embedded in a lipid bilayer, and which is capable of binding the compound, and b) optionally at least one accessory molecule that directly or indirectly binds an intracellular loop and/or the C-terminus of the G protein coupled receptor, wherein the G protein coupled receptor comprises one or more subunits that are the same or different, and wherein the G protein coupled receptor, and/or accessory molecule when present, in combination comprise a bioluminescent protein and an acceptor molecule, ii) simultaneously or sequentially with step i) providing a substrate of the bioluminescent protein, and allowing the bioluminescent protein to modify the substrate, iii) determining if step ii) modulates bioluminescent resonance energy transfer (BRET) between the bioluminescent protein and the acceptor molecule, wherein the spatial location and/or dipole orientation of the bioluminescent protein relative tG the acceptor molecule is altered when the compound binds the G protein coupled receptor, and wherein when expressed in a cell the N-terminus of the G protein coupled receptor, or subunits thereof, is outside the cell and the C-terminus inside the cell.
Patent NZ-596257-A (NZ)
Title: An electrically heated smoking system
Inventor: CHEMLA MARC-ROBERT
IPC: A24F40/95
Filed: 2010-05-18
Abstract: 596257 Disclosed is an electrically heated smoking system (101) with a secondary unit (105) capable of receiving a smoking article (107) having an aerosol-forming substrate. The secondary unit has at least one heating element and an interface for connection to a primary power supply that supplies electrical power to the at least one heating element. A secondary power supply supplies electrical power to the at least one heating element. Secondary circuitry controls supply of electrical power from the primary power supply to the at least one heating element in a pre-heating mode. During the pre-heating mode, the temperature of the aerosol-forming substrate is increased to an operating temperature. The secondary circuitry also controls supply of electrical power from the secondary power supply to the at least one heating element in a smoking mode, during which the temperature of the aerosol forming substrate is maintained at substantially the operating temperature.
Patent NZ-597502-A (NZ)
Title: Purification of acetic acid from wood acetylation process using extraction
Inventor: WARNER R
IPC: B27K3/36
Filed: 2009-02-27
Abstract: 597502 A method of purifying acetic acid containing terpene and terpenoid impurities, provided that the acetic acid is not glacial acetic acid, comprising: (a) combining acetic acid containing terpene and terpenoid impurities, provided that the acetic acid is not substantially dry, water and a suitable organic solvent, which is substantially immiscible with acetic acid and water, to form a separating composite extraction medium wherein the weight ratio of acetic acid: water is at least 1: 1, and said acetic acid supplied to the separating composite extraction medium contains more than 200 ppm terpene and terpenoid impurities, based on the combined weight of acid and impurities only; (b) separating the components of step (a) into an organic phase and an aqueous acid phase, wherein the terpene and terpenoid impurities are concentrated in the organic phase and the aqueous acid phase is purified of terpene and terpenoid impurities, and the purified acid contains less than 50 ppm terpene and terpenoid impurities based on the weight of acid and impurities only; (c) recovering the purified aqueous acid phase; and (d) drying the purified acetic acid.
Patent NZ-597550-A (NZ)
Title: Process for the preparation of o-desmethyl venlafaxine and intermediate for use therein
Inventor: KANKAN RAJENDRA NARAYANRAO
IPC: A61K31/135
Filed: 2010-07-14
Abstract: Disclosed is a process for preparing 2-(4-benzyloxy-phenyl)-3·dimethylaminopropionic acid alkyl ester of Formula (A), comprising the steps of: a) esterifying (4-benzyloxyphenyl)-acetic acid to form a (4-benzyloxy-phenyl)-acetic acid alkyl ester; b) reacting the (4-benzyloxy-phenyl)-acetic acid alkyl ester with paraformaldehyde in the presence of an inorganic base and a phase transfer catalyst to form a 2-(4-benzyloxy-phenyl)-acrylic acid alkyl ester of; c) reacting the 2-(4-benzyloxy-phenyl)-acrylic acid alkyl ester with dimethylamine in the presence of a Lewis acid catalyst to form the compound of formula A.
Patent NZ-598362-A (NZ)
Title: Phthalocyanine derivative consisting of a mixture of 4 isomers
Inventor: RONCUCCI GABRIO
IPC: A61K31/555
Filed: 2010-07-30
Abstract: 598362 Disclosed herein is a phthalocyanine derivative of formula (I) consisting of 4 isomers wherein the isomer B is ?12.5% by weight; a process for the preparation thereof comprising: chromatographic purification of an isomeric mixture of formula (II), and treatment of the amine intermediate of formula (III) to obtain the chloride form of formula (I); and and the use thereof in the treatment of hyperproliferative diseases, psoriasis, actinic keratosis and pre-tumour, tumour pathologies or microbial infections.
Patent NZ-599443-A (NZ)
Title: Method and system for thin chip digester cooking
Inventor: ENGSTROM JOHAN
IPC: D21C3/02
Filed: 2010-11-19
Abstract: 599443 Disclosed herein is a method and apparatus to cook thin chips in a continuous digester vessel, the method including: introducing thin chips having a thickness of no more than 6mm, into a chip bin; adding white (cooking) liquor to the chip bin or to a chip transport passage extending from the chip bin to an upper inlet of the continuous digester vessel; injecting medium pressure steam or another heated fluid to an upper region of the digester vessel to elevate a cooking temperature of the chips in the vessel to at least 130 degrees Celsius; cooking the chips in the vessel as the chips flow downward through the vessel without substantial extraction or introduction of liquor in the cooking section of the vessel; injecting wash liquid to a lower region of the vessel; extracting at least wash liquid through a wash liquid extraction screen in the lower region of the vessel and above the injection of the wash liquid, and discharging the cooked thin chips from the lower region of the vessel.
Patent NZ-599626-A (NZ)
Title: Chair and Chair Fixing
Inventor: PUGLIA GERARD
IPC: E04C5/16
Filed: 2012-04-27
Abstract: 599626 A chair has support feet and has a surrounding upper structure that can retain an insert with an enlarged foot portion in both upper and lower directions.
Patent NZ-600385-A (NZ)
Title: Huller device
Inventor: FERRANDEZ JOSEPH
IPC: A23N15/02
Filed: 2010-11-22
Abstract: 600385 Disclosed is a huller device for hulling bunches of grapes after the harvest, or other fruit harvested in bunches to separate the fruits from the stalks. The huller device includes two shaking units arranged side by side, defining a vertical space into which the harvest is directed by gravity and, means for collecting the fruit and the stalks, said means being arranged under said shaking units. Each of the shaking units comprises a series of vertically oriented, regularly spaced parallel fingers suspended from a horizontal shaft, while the two horizontal shafts of the two shaking units are parallel and connected to drive means enabling transmission to them of an oscillatory pivoting movement so as to drive said fingers in an oscillatory pendular movement.
Patent NZ-603805-A (NZ)
Title: Methods for increasing and mobilizing hematopoietic stem cells
Inventor: STROM EVGUENIA
IPC: A61K38/08
Filed: 2008-01-09
Abstract: NZ 603805 Disclosed is the use of a composition for producing a non-totipotent stem cell population comprising a lipopeptide of the formula as disclosed in the abstract drawing wherein, R1 represents H or -CO-R4, R2, R3 and R4 independently are H or optionally substituted C6-C20 aliphatic, X is a peptide selected from the group consisting of SEQ ID NOS: 8, 16-18, 20, and 21 disclosed in the specification, and Z is S or CH2; and wherein the non-totipotent stem cell population is not produced in a human.
Patent NZ-610174-A (NZ)
Title: Process for the treatment of contaminated water by means of adsorption and nanofiltration
Inventor: BAGATIN ROBERTO
IPC: C02F103/36
Filed: 2011-11-03
Abstract: A process for the treatment of contaminated water comprises sending the contaminated water to a treatment system. The system comprises at least one adsorption (3) unit and at least one nano-filtration unit (7). The at least one adsorption (3) unit includes at least one microporous or mesoporous alumino-silicate and the at least one nano-filtration unit (7) includes at least one hydrophilic nano-filtration membrane. The hydrophilic nano-filtration membrane has a contact angle with water lower than or equal to 45°. The water is contaminated by polar and/or apolar organic compounds, and/or by heavy metal salts, and/or by oil dispersed or in emulsion.
Patent NZ-614230-A (NZ)
Title: Container construction
Inventor: GREER ALEXANDER TOWNSHERD
IPC: B65D1/42
Filed: 2013-04-08
Abstract: A bottle (1) which includes at least two compartments (8, 9) and at least one passage (7) between the compartments. The passage is configured to constrict under pressure to restrict fluid transfer between the compartments. The passage is formed as a consequence of a gap created by two opposing concave panels (4) in the side wall (3) of the bottle.
Patent NZ-615593-A (NZ)
Title: Combination of a phosphatidylinositol-3-kinase (pi3k) inhibitor and a mtor inhibitor
Inventor: FRITSCH CHRISTINE
IPC: C07D277/46
Filed: 2012-04-23
Abstract: Disclosed is a pharmaceutical combination comprising a phosphatidylinositol- 3-kinase (PI3K) inhibitor compound of the general formula (A), wherein the substituents are as described in the specification, and at least one mammalian target of rapamycin (mTOR) inhibitor. The pharmaceutical composition comprising such a combination is used in the treatment proliferative diseases, more specifically of mammalian target of rapamycin (mTOR) kinase dependent diseases.
Patent NZ-617974-A (NZ)
Title: Strain belonging to bacillus genus, microbiological agent, and plant cultivation method
Inventor: AMAKI Yusuke
IPC: C12R1/07
Filed: 2012-05-21
Abstract: Disclosed are two Bacillus strains, namely Bacillus sp. AT-332 containing 16S rDNA represented by SEQ ID NO: 2 and Bacillus sp. AT-79 containing 16S rDNA represented by SEQ ID NO: 3, wherein SEQ ID NOs: 2 and 3 are disclosed in the specification. Also disclosed is a method for cultivating plants by treating the plants with one of the above mentioned strains.
Patent NZ-618119-A (NZ)
Title: Multilayer polyester film for ready meals
Inventor: FORLONI ROBERTO
IPC: B32B27/36
Filed: 2012-05-24
Abstract: Disclosed are coextruded, biaxially oriented multilayer films comprising a base layer comprising a polyester having an intrinsic viscosity greater than 0.75 dl/g and a heat-sealable layer directly adhered to said base layer, said heat-sealable layer comprising: - 25-70% by weight of amorphous polyester having a melting temperature not higher than the melting temperature of the polyester of the base layer, wherein said amorphous polyester is selected among those deriving from an aliphatic diol and a cycloaliphatic diol and an aromatic dicarboxylic acid; - 10-20% by weight of a thermoplastic resin, and - 20-60% by weight of a further polyester which is different from the first amorphous polyester, characterized by a glass transition temperature Tg not higher than 80°C and/or a melting point higher than 240°C. Also disclosed are packages comprising a container, a food product and the above coextruded, biaxially oriented multilayer film. The packages are particularly suitable for “ready-meals” to be used in conventional oven at high temperatures.
Patent NZ-618889-A (NZ)
Title: Rapid and accurate analysis of protein sialylation
Inventor: WANG ZIHAO
IPC: G01N30/02
Filed: 2012-07-05
Abstract: A method of determining the sialylation content of a protein is disclosed. A protein is prepared for analysis and the prepared protein is enzymatically treated by diving the prepared protein into a plurality of protein samples. These samples of prepared protein are incubated separately under three conditions: with a) beta-galactosidase, with b) beta-galactosidase and alpha-sialidase, and c) without an enzyme. After the enzyme treatment, high performance anion exchange chromatography with pulsed amperometric detection (HPAEC PAD) is used to make a quantitative determination of the total galactose in the sample, the non sialylated galactose and the exogenous galactose in the medium. The determination of the values makes it possible to deduce the percentage of sialylation of the protein.
Patent NZ-622329-A (NZ)
Title: Aniline derivatives,their preparation and their therapeutic application
Inventor: FEUTRILL JOHN
IPC: C07D295/088
Filed: 2012-09-07
Abstract: The present disclosure relates to aniline derivatives of formula (I), to their preparation and to their therapeutic application, for example in treating glaucoma: Formula (I), R1a represents H, an halogen, a (C1-C6)alkyl or a CN; R1b represents H, an halogen or a (C1-C6)alkyl; R1c represents H or a(C1-C6)alkyl; R2 represents H, an halogen, an OH, an O-(C1-C6)alkyl or (C1-C6)alkyl; R3 represents H, an halogen, a (C1-C6)alkyl, an OH, an O-(C1-C6)alkyl, a CONH2 or CN; R4 represents H, an halogen or a (C1-C6)alkyl; R5 represents H or F: R7 represents H or F; R8 represents H or F; R9 represents H or (C1-C)alkyl, or one of its enantiomers.