baber/WOPTO huggingface dataset:
Patent DE-69513111-T2 (DE)
Inventor: PENNETREAU PASCAL
IPC: B01J27/135
Filed: 1995-08-29
Granted: 2000-08-17
Abstract: Hydrofluorination of chloro(fluoro)butane of formula (I) C4H5ClxF(5-x) using hydrogen fluoride, is performed in the presence of a catalyst (II) selected from Gp IIIa, IVa, IVb, Va, Vb and Vb metal derivs. In (I), x is 1-5. Also claimed is the prepn. of 1,1,1,3,3-pentafluorobutane (III) by the above process. (II) is Sn or Sb chloride, fluoride or chlorofluoride (pref. antimony pentachloride). 0.001-1 mol. (II) w.r.t. (I) are used. The mol ratio HF to (I) is 4-25. The reaction is effected at 50-150 deg. C and 2-40 bar. (I) is 1,1,3,3-tetrafluoro-1-chlorobutane (Ia); 1,3,3-trifluoro-1,1-dichlorobutane or 1,1,3-trifluoro-1,3-dichlorobutane. (I) is obtd. by reaction of vinylidene chloride with HF.
Patent DE-69520108-T2 (DE)
Inventor: DEELEY GEORGE
IPC: G01N31/00
Filed: 1995-09-20
Granted: 2001-06-21
Abstract: An improved assay method and device for use in such method in which soluble releasable reagents are used.
Patent DE-69604386-T2 (DE)
Inventor: MEERMAN JOHANNES JACOBUS
IPC: D01D5/18
Filed: 1996-03-01
Granted: 2000-04-13
Abstract: The invention pertains to a process for spinning fibers or filaments from a spinnable solution using a centrifuge of which the wall has one or more spinning orifices and in which process the spinning solution is jetted from the centrifuge into a coagulant inside a jacket, characterized in that the angular velocity of the centrifuge multiplied by the inner radius of the jacket is higher than 20 m/s. In addition, the fibers or filaments made by means of this process have very favorable pulp properties.
Patent DE-69612317-T2 (DE)
Inventor: CASAGRANDE SERGIO
IPC: E21B3/025
Filed: 1996-01-30
Granted: 2001-07-12
Abstract: Casing rotating device (10) for drilling machines, the device being associated and coaxial with a device (13) for the rotation of a drilling tool for the obtaining of foundation piles, the drilling tool rotation device (13) having its own motor, the rotary casing-oscillator device (10) being located in a position below the drilling tool rotation device (13) and being associated with a reduction-gear and torque-multiplier transmission assembly (15,115).
Patent DE-69612855-T2 (DE)
Inventor: DULAC BERNARD
IPC: H04N5/765
Filed: 1996-07-30
Granted: 2001-09-13
Abstract: An apparatus includes a first bus, a second bus, and a storage module having a first and second output with the first output being connected to the first bus and a second output being connected to the second bus. A first buffer storage and a second buffer storage in which the first buffer storage is connected to the first bus and the second buffer storage is connected to the second bus. The second buffer storage includes an error correction module. First and second network adapters are connected to the first and second buses respectively. The first network adapter also includes a connection to the first buffer. A processor in the apparatus includes a first processor circuitry for transferring the data using a first path through the first output in the storage module to the first buffer storage and from the first buffer storage to the first network adapter. A second processor circuitry is for transferring data using a second path through the second output to the second buffer storage through the error correction module and from the second buffer storage to the second network adapter, wherein the second processor circuitry is responsive to an error in the storage module.
Patent DE-69619706-T2 (DE)
Inventor: SCP HIGH TECH PROPERTIES MONAC
IPC: A21D13/00
Filed: 1996-03-21
Granted: 2002-12-12
Abstract: Bread with a pre-fermentation dough moisture content of 85-95 %, i.e. an abnormally high content, is disclosed. The amount of yeast in the dough is of less than 2.5 wt % and the dough contains pre-fermented dough. The fermentation process is abnormally long, lasting over ten hours.
Patent DE-69621618-T2 (DE)
Inventor: WOELFEL PETER
IPC: B65B63/02
Filed: 1996-03-05
Granted: 2003-02-06
Abstract: A handling device for conveying layered cellulose products (cotton wool pads 1) formed successively during production between a production station (stamping machine 2) and a packaging station is provided with an intermediate storage system (4) with at least one pair of separate holding chambers (5, 6) for the serial holding of the cellulose products (cotton wool pads 1) delivered successively from the production station (stamping machine 2) in a number corresponding to the packaging unit and for the transfer of the cellulose products (cotton wool pads 1) held in this way as a package (67) into a respective conveying cartridge (10). One holding chamber (5) of the pair, of which there is at least one, can be coupled to the outlet of the production station (stamping machine 2) and at the same time the other holding chamber (6) in a transfer station (11) to the respective conveying cartridge (10) alternately.
Patent DE-69631026-T2 (DE)
Inventor: HONDA SHINKICHI
IPC: C11D1/10
Filed: 1996-07-11
Granted: 2004-09-09
Abstract: The present invention relates to a cleansing composition comprising at least one compound selected from N-long chain acylamino acids represented by formula (I): <CHEM> (wherein n represents 1 or 2; and R represents a saturated or unsaturated hydrocarbon group having 5 to 23 carbon atoms), and salts thereof.
Patent DE-69637012-T2 (DE)
Inventor: DORIN GLENN J
IPC: A23L21/15
Filed: 1996-06-07
Granted: 2009-01-08
Abstract: Aqueous formulations of TFPI (tissue factor pathway inhibitor) include L-arginine and/or a solubilising agent selected from the group consisting of: an acetate ion; a sulfate ion; sodium chloride; a citrate ion; an isocitrate ion; glycine; glutamate; a succinate ion; histidine; imidazole; sodium dodecyl sulfate; or a charged polymer. The invention facilitates the solubilization, formulation, purification and refolding of TFPI. <IMAGE>
Patent DE-69706487-T2 (DE)
Inventor: TRKOVNIK MLADEN
IPC: C07D491/147
Filed: 1997-07-24
Granted: 2002-05-08
Abstract: The present invention relates to novel coumarin quinolone carboxylic acids wherein the pyridone system is fused in 3,4-, 6,7- and 7,8-positions of the coumarin system, of the general formula I <CHEM>  wherein   R<1>R<2> = -NHCH=C(CO2R<6>)CO-, R<3> = NO2 or NH2, R<4> = R<5> = H, R<6> = H or C2H5; R<1>R<2> = -NHCH=C(CO2R<6>)CO-, R<3> = R<4> = H, R<5> = F, R<6> = H or C2H5; R<1>R<2> = -CO(CO2R<6>)C=CHNH-, R<3> = R<4> = R<5> = H, R<6> = H or C2H5; R<1>R<2> = R<3>R<4> = -NHCH=C(CO2R<6>)CO-, R<5> = H, R<6> = H or C2H5; R<1> = H or OH, R<2> = R<5> = H, R<3>R<4> = -NHCH=C(CO2R<6>)CO-, R<6> = H or C2H5; R<1> = OH, R<2> = R<3> = H, R<4>R<5> =-CO(CO2R<6>)C=CHNH-, R<6> = H or C2H5; R<1> = R<5> = H, R<2> = CH3 or CF3, R<3>R<4> = -CO(CO2R<6>)C=CHNH-, R<6> = H or C2H5,  as well as pharmaceutically acceptable salts thereof. The object of the invention are also processes for the preparation of novel coumarin quinolone carboxylic acids and the biological action thereof.
Patent DE-69713230-T2 (DE)
Inventor: CARLOTTI ARNAUD
IPC: C12Q1/6895
Filed: 1997-03-24
Granted: 2003-01-23
Abstract: The detection and characterisation of yeasts, particularly those of medical and industrial interest, is disclosed. The aim is to provide powerful, reliable and simply and reproducibly usable DNA probes specific for numerous yeasts. For this purpose, among others, a yeast-specific and/or -infraspecific detection probe is provided which consists of at least one part of at least one DNA and/or RNA fragment F from rDNA that does not code for rRNA synthesis and is located in the IGR (rDNA 25S and rDNA 18S). This iterative rDNA includes at least two repeated subsequences with a mutual homology of >/= 50 %. A detection method using said probe, as well as nucleic acid sequences capable of being included in the probe, are also disclosed. Said probe is useful for detecting/identifying yeast (e.g. C. krusei, G. candidum), as an epidemiological marker or strain tracer, and in anti-yeast therapy.
Patent DE-69719219-T2 (DE)
Inventor: HERMODSSON GOERAN
IPC: B65D8/18
Filed: 1997-11-28
Granted: 2003-07-24
Abstract: The disclosure relates to a method of producing a packaging container for liquid contents, comprising a casing (2) and a top portion (3). The casing (2) is formed winding of a web-shaped multilayer material into a sleeve form, whereafter the material edges are sealed to one another in a liquid-tight joint seam (9) extending longitudinally of the sleeve. The top portion is produced in that thermoplastic material is extruded for the formation of a hose (15), whereby the hose (15) is subjected to blow moulding and formed into a number of continuous top portions (3) which are mutually united alternatingly with the necks (5) and with the cylindrical portions (10) to one another, that the top portions (3) are divided into individual top portions (3). The upper end of the casing (2) is united in a liquid tight fashion to the lower end of a individual top portion (3). <IMAGE>
Patent DE-69726461-T2 (DE)
Inventor: TURNER ANTHONY L
IPC: B02C18/18
Filed: 1997-08-14
Granted: 2004-09-09
Abstract: A wood-chipping machine (FIG. 1) has a plurality of cutters (38,40,42) carried by a flywheel (30) which is rotated to move the cutters across a throat through which material to be chipped is fed, and in which each cutter is substantially frustoconical and hence circular and a plurality of such cutters form a blade at a generally radial location of the flywheel (30). These facilitate blade replacement in the event of wear eg by adjusting the worn cutter angularly. <IMAGE>
Patent DE-69728570-T2 (DE)
Inventor: MITRA SEKHAR
IPC: A61F7/02
Filed: 1997-12-05
Granted: 2005-02-24
Abstract: The present invention relates to a nasal dilator which comprises a means for dilating the nostrils and a thermal element, which can be worn on the nose of a human for an extended period of time, as well as a method of treatment for relief of nasal congestion/blockage, sinus discomfort and pain, and other cold and/or allergy symptoms associated therewith, by applying said nasal dilator to the nose of a human in need of such treatment.
Patent DE-69733958-T2 (DE)
Inventor: BENSIMON AARON
IPC: G16B20/10
Filed: 1997-10-30
Granted: 2006-05-18
Abstract: The invention concerns a method for detecting or locating one or several genes of one or several specific A DNA sequence or one or several molecules reacting with DNA on a B DNA characterised in that it consists in: (a) fixing and combing a certain amount of said B DNA on a combing surface; (b) reacting the product of the B combing with one or several probes, linked with the gene(s) or specific A DNA sequences, or with the molecules capable of reacting with DNA; (c) extracting information corresponding to at least one of the following categories: (1) the position of the probes, (2) the distance between the probes, (3) the size of the probes (the total sum of sizes for quantifying the number of hybridised probes) for determining therefrom the presence, the location and/or the amount of genes or specific A DNA sequences. This method can be used in particular for the diagnosis of genetic diseases.
Patent DE-69736129-T2 (DE)
Inventor: SOFF GERALD
IPC: C12N5/077
Filed: 1997-09-17
Granted: 2007-01-04
Abstract: The invention provides methods of generating angiostatin in  vitro  comprising contacting plasminogen with a plasminogen activator and a sulfhydryl donor or contacting plasmin with a sulfhydryl donor. The invention also provides a method of treating angiogenic diseases by administering to an animal suffering from such a disease a sulfhydryl donor and, optionally, a plasminogen activator, plasminogen or plasmin. The invention further comprises a composition for generating angiostatin comprising a sulfhydryl donor and a plasminogen activator. The invention also provides a container holding a sulfhydryl donor and/or a plasminogen activator, said container having a label thereon instructing administration of the sulfhydryl donor and/or plasminogen activator to an animal suffering from an angiogenic disease. The invention further provides plasminogen fragments-whose N-terminal amino acid is the same as that of plasmin and whose C-terminal amino acid is located in kringle 5 and which inhibit angiogenesis, antibodies which bind selectively to these fragments, methods and kits for using the antibodies, methods and materials for making the fragments by recombinant DNA techniques, and a method of treating an angiogenic disease comprising administering an effective amount of one of the fragments. Finally, the invention provides a method of treating an angiogenic disease comprising administering a transgene coding for one of the fragments.
Patent DE-69801056-T2 (DE)
Inventor: SAMAIN DANIEL
IPC: C03C17/30
Filed: 1998-08-14
Granted: 2002-11-07
Abstract: A solid material is treated, the chemical structure of which defines reactive protogenic hydrophillic functions accessible to gases, by applying at least one gas stream (3) onto at least one microdispersion (5) of at least one grafting reagent RX produced on the solid material, R being a hydrophobic group, X being chosen so that HX is volatile under normal conditions, R and X being chosen so that the reaction of RX on the hydrophillic functions produces covalent grafting of the hydrophobic group R with formation of the compound HX, it being possible for the reaction to be carried out in a solid/gas heterogeneous medium on all the reactive hydrophillic functions accessible to gases and only on these. The invention extends to the hydrophobic solid material obtained, and is applicable to the obtaining of natural or artificial fibrous or inorganic structures impermeable to water and to aqueous solutions and/or absorbing fats.
Patent DE-69801115-T2 (DE)
Inventor: VAN WINKELEN CORNELIS
IPC: B01D61/04
Filed: 1998-11-17
Granted: 2002-03-14
Abstract: The present invention relates to a method for purifying water, in particular ground water, under anaerobic conditions, using a membrane filtration unit, wherein the following steps are carried out: 1) connecting the membrane filtration unit (8) to a rinsing unit (11); then 2) passing a rinsing agent from the rinsing unit (11) through the membrane filtration unit (8) so as to create anaerobic conditions in the membrane filtration unit (8); and 3) passing the water to be purified through the membrane filtration unit (8), in which anaerobic conditions have thus been created in step 2), wherein the connection (12) between the membrane filtration unit (8) and the rinsing unit (11) is then shut off so that the anaerobic conditions in the membrane filtration unit (8) obtained in step 2) are maintained while the water to be purified is passed through said membrane filtration unit (8). The present invention furthermore relates to a device for purifying water, and to drinking water obtained by using such a device and/or method.
Patent DE-69810310-T2 (DE)
Inventor: LISLE EDGAR
IPC: G01P3/489
Filed: 1998-08-25
Granted: 2003-10-16
Abstract: The method uses a vehicle 1, having a sender pulse generating device 2 fitted to its gearbox 3, at the start of a track 4 of known length. The track 4 has a starting marker 5 and a finishing marker 6, e.g. V-blocks at spaced intervals on the track 4, activated by an antenna mounted on the vehicle 1. A signal processing means 7 counts the integral number of pulses and determines the fractions of a pulse length at the starting and finishing markers 5,6. A microprocessor controls the signal processing combining time intervals, which represent fractions of a pulse length at the starting and finishing markers, with the integral number of pulses effectively to add both fractions to the pulse count and thus accurately determine how many pulses and what fraction of a pulse is generated when the vehicle travels, over the track 4, between the starting and finishing markers 5,6.
Patent DE-69810561-T2 (DE)
Inventor: KRUAJITCH ANDRE-JEAN
IPC: A63C9/00
Filed: 1998-09-24
Granted: 2003-08-21
Abstract: The plate (1) is a single rigid piece made from molded synthetic material. Its middle zone (5) is thinned by two hollows in its lower surface. These are at least partially filled with supple elastic material (9,10). The center of the plate (6) is fixed to the ski (2) by screws. The plate elevates the ski fixtures above the ski. The plate is guided along the ski and is kept vertical. It is a single, rigid piece which is thinned in the middle where it is also pliable.
Patent DE-69811086-T2 (DE)
Inventor: MATHIESEN BENNY MARTIN
IPC: B32B27/12
Filed: 1998-08-06
Granted: 2003-07-31
Abstract: The invention relates to a method of manufacture of a composite product including at least one layer of reinforced woven material and at least one layer of PTFE foil or ePTFE foil, where the foil or foils are laminated together with the layer or layers of woven material under the use of heating and pressurizing, where the composite material subsequently is cooled to a fully or partly fixed state. According to a preferred embodiment the composite is fixated by means of one or two cooperating pressure surfaces under a relative high pressure. By the invention a form stable composite material having a considerable enhanced E-modulus is achieved.
Patent DE-69812937-T2 (DE)
Inventor: THOMAS E
IPC: G03H1/08
Filed: 1998-06-09
Granted: 2003-12-24
Abstract: Systems and methods for direct-to-digital holography are described. An apparatus includes a laser; a beamsplitter optically coupled to the laser; a reference beam mirror optically coupled to the beamsplitter; an object optically coupled to the beamsplitter, a focusing lens optically coupled to both the reference beam mirror and the object; and a digital recorder optically coupled to the focusing lens. A reference beam is incident upon the reference beam mirror at a non-normal angle, and the reference beam and an object beam are focused by the focusing lens at a focal plane of the digital recorder to form an image. The systems and methods provide advantages in that computer assisted holographic measurements can be made.
Patent DE-69814837-T2 (DE)
Inventor: FANTUCCI MARIO
IPC: C07D277/30
Filed: 1998-01-12
Granted: 2004-02-19
Abstract: A process for the preparation of heteroaryl-zinc halides of the formula (II): Het-Zn-X, wherein Het is an optionally substituted 5 or 6 membered aromatic heterocyclic group with one or two heteroatoms selected among nitrogen, oxygen or sulphur; X is a chlorine, bromine or iodine atom; comprising metallation reaction of heteroarylhalide with metallic zinc optionally activated by washing with acids, is described. Compounds of the formula (II) are intermediates useful in the synthesis for the preparation of compounds endowed with pharmacological activity.
Patent DE-69817151-T2 (DE)
Inventor: BAKKEN KNUT
IPC: F25B9/00
Filed: 1998-01-08
Granted: 2004-06-09
Abstract: PCT No. PCT/NO98/00004 Sec. 371 Date Jun. 30, 1999 Sec. 102(e) Date Jun. 30, 1999 PCT Filed Jan. 8, 1998 PCT Pub. No. WO98/30847 PCT Pub. Date Jul. 16, 1998A refrigeration system having a closed circulating circuit filled with a refrigerant which on evaporation expands and gives rise to an increase in pressure in the whole or in parts of the circulating circuit, and which at ambient temperature has a saturation pressure that is higher than the maximum working pressure in the refrigeration circuit. A refrigeration of this kind may, for example, be carbon dioxide. By allowing vaporized refrigerant to condense against the surface of the refrigerant in liquid phase, contained in a container that is insulated and has adapted size and adapted liquid level, the pressure in the circulating circuit can be maintained below the maximum working pressure of the refrigeration circuit. Thus undesirable build-up of pressure in the event of, e.g., a period of inoperation or breakdown, is prevented, and the circulating circuit of the refrigeration system can be designed and made for a pressure which is below the saturation pressure at ambient temperature of the refrigerant used, and the refrigeration system can be made using conventional or at least virtually conventional elements, whereby the total system costs are reduced considerably in relation to a total system which is built to withstand higher pressure, e.g., the saturation pressure at room temperature of the refrigerant. Starting up after, e.g., a period of inoperation or breakdown is secured with valves which provide a controlled fall in pressure in an insulated container after an increase in pressure in the same container exceeding the maximum working pressure of the circuits.
Patent DE-69817394-T2 (DE)
Inventor: KOTWICA ROLAND
IPC: B01J19/26
Filed: 1998-11-23
Granted: 2004-07-01
Abstract: This process for the manufacture of norbornene from dicyclopentadiene (DCPD) and ethylene is characterized in that the DCPD is subjected to partial monomerization to CPD by preheating:at a temperature of 140° C. to 240° C.; andunder a pressure of 20 to 300 bar abs., before reacting it with the ethylene;with an ethylene/DCPD molar ratio of 1 to 20;at a temperature of 200° C. to 320° C.;under a pressure of 20 to 300 bar abs.; andwith a residence time of 1 to 10 minutes, under stable reaction conditions between the DCPD, the CPD and the ethylene.
Patent DE-69817826-T2 (DE)
Inventor: COOPER B
IPC: C07D413/14
Filed: 1998-06-15
Granted: 2004-07-15
Abstract: Novel compounds of formula (1.0) or a pharmaceutically acceptable salt or solvate thereof, wherein: a represents N or NO<->; R<1> and R<3> are the same or different and each represents halo; R<2> and R<4> are the same or different and each is selected from H and halo, provided that at least one of R<2> and R<4> is H; T is a substituent selected from SO2 R or (A); Z is O or S; n is zero or an integer from 1 to 6; R is alkyl, aryl, arylalkyl, heteroaryl, heteroarylalkyl, cycloalkyl, heterocycloalkyl, or N(R<5>)2; R<5> is H, alkyl, aryl, heteroaryl or cycloalkyl. Also disclosed are methods of inhibiting farnesyl protein transferase and methods for treating tumor cells.
Patent DE-69827013-T2 (DE)
Inventor: SIMMONDS ADRIAN
IPC: G01N33/53
Filed: 1998-07-31
Granted: 2006-03-02
Abstract: Nucleoside analogues or base analogues having structure (I), where X=O or NH or S, Y=N or CHR6 or CR6, W=N or NR6 or CHR6 or CR6 or S, n=1 or 2; each R6 is independently H or O or alkyl or alkenyl or alkoxy or aryl or a reporter moiety; where necessary (i.e. when Y and/or W is N or CR6 where R6 is not O) a double bond is present between Y and W or W and W, and Q is H or a sugar or a sugar analogue or a nucleic acid backbone or backbone analogue.
Patent DE-69828197-T2 (DE)
Inventor: IKEDA KAZUHITO
IPC: C07C233/83
Filed: 1998-10-22
Granted: 2005-12-08
Abstract: A compound of the formula: <CHEM>  wherein     Ar is optionally substituted phenyl, etc. ; n is 0, 1 or 2; R<1> is hydogen atom, optionally substituted alkyl, etc. ; R<2> and R<3> are independently optionally substituted alkyl, etc. ; R<4> and R<5> are independently hydrogen atom or optionally substituted alkyl; R<6> is hydrogen atom, hydroxy or alkyl; or a pharmaceutically acceptable salt thereof is useful as a medicament for treating retinal degenerative disorders and the like.
Patent DE-69830658-T2 (DE)
Inventor: POTTER DAVID
IPC: A61M5/20
Filed: 1998-07-06
Granted: 2006-05-11
Abstract: A syringe, of the kind in which a dose of the drug is entrained by a fluid flow for delivery, is characterised by an upstream portion which provides, or is arranged to provide, a source of fluid under pressure; a downstream nozzle portion; between the upstream and downstream portions an intermediate portion having two relatively sliding parts (34,35) providing therebetween a closed pocket (40) containing the dose; and an actuator mechanism (16,18,21) for initiating a flow of the fluid from the source whereupon the pressure of the fluid applies to one of the slidable parts a force causing the one part to slide relatively to the other part and to open the pocket thereby exposing the dose for entrainment by the fluid as it flows through the intermediate portion and to and through the nozzle. <IMAGE>