baber/WOPTO huggingface dataset:
Patent DK-1154738-T3 (DK)
Inventor: LAMBRECHT GREGORY H
IPC: A61F/
Filed: 2000-01-27
Granted: 2010-07-26
Abstract: Devices and methods for performing intrvenous vascular procedures without cardiac bypass. The devices include various embodiments of temporary filter devices (10), temporary valves (26, 100), and prosthetic valves (80, 85, 86, 90). The temporary filter devices (10) have one or more cannulae (2) which provide access for surgical tools for effecting repair of the cardiac valves. A cannula (2) may have filters (3) of various configurations encircling the distal region of the cannula, which prevents embolism material from entering the coronary arteries, and aorta. In one embodiment, a set of valve leaflets (70, 71) extend peripherally from the filter to prevent blood flow through peripheral arteries. The temporary valve devices (26) may also have one or more cannulae (2') which guide insertion of the valve into the aorta. The valve devices (26) expand in the aorta to occupy the entire flow path of the vessel. In one embodiment, the temporary valve (26) is a disc of flexible, porous material that acts to filter blood passing therethrough. In another embodiment, the temporary valve (100) has leaflets (111) which act in concert to alternately block or allow blood flow.
Patent DK-1154955-T3 (DK)
Inventor: THALHAMMER FRANZ
IPC: C01C3/16
Filed: 2000-02-04
Granted: 2003-01-20
Abstract: A process is described for preparing sodium dicyanamide, in which cyanamide is reacted simultaneously with sodium hydroxide solution and cyanogen chloride in aqueous solution at temperatures of 20 to 100° and a pH of 7.0 to 10.0. By means of the inventive process it is possible, starting from raw materials which are available in technical-grade quality, to prepare sodium dicyanamide in good yields of 75 to 95% and very high purities of up to 100% in a very environmentally friendly manner, for which reason this process is particularly highly suitable for the industrial scale.
Patent DK-1239836-T3 (DK)
Inventor: TOURAUD FRANCK
IPC: A61K8/30
Filed: 2000-10-11
Granted: 2003-11-24
Abstract: A suspension of vector particles (PV) based on polyamino acids and have a mean hydrodynamic diameter between 30 and 120 nm, and an insulin load factor of from 5 to 25% of associated insulin volume relative to the polyamino acid volume forming the vector particles. The polyamino acids are double-block polymers containing hydrophilic and hydrophobic monomers. The suspension may be prepared by copolymerizing N-carboxy anhydrides of hydrophobic monomers and precursors of hydrophilic monomers, in the presence of N-methyl pyrrolidone and methanol. The copolymer is optionally neutralized, subjected to dialysis, concentrated and water is eliminated to produce a solid powder, which can be suspended in a liquid to produce the colloidal suspension. Active principles such as insulin or vaccines are associated with the carrier particles to prepare special pharmaceutical products.
Patent DK-1274288-T3 (DK)
Inventor: NAUNDORF GERHARD PROF DR
IPC: H05K3/10
Filed: 2001-12-19
Granted: 2005-06-06
Abstract: Production of strip conductor structures comprises mixing a thermally stable insoluble inorganic metal compound stable in aqueous, acidic or alkaline metallization baths with a carrier material; processing the material to components or applying on components as a coating; releasing heavy metal seeds in the region of the strip conductor structures to be produced; and metallizing the region.  Preferred Features: The heavy metal seeds are released using electromagnetic radiation and removed forming an adhesion-promoting surface. The inorganic metal compounds are monoxides of the d-metals of the periodic table or higher oxides, preferably spinels. The inorganic metal compound contains copper. The carrier material is a thermoplastic or a duroplastic material.
Patent DK-1252159-T3 (DK)
Inventor: HEYN DR ARMIN
IPC: C07D417/06
Filed: 2001-01-08
Granted: 2004-08-16
Abstract: The present invention relates to a process for the preparation of compounds of the formula (I)in which R<1>, A, D, X and Z have the meanings given in the description,by reacting compounds of the formula (II)in whichA, D and X have the meanings given above,with a base and in the presence of a diluent, and subsequently reacting the reaction mixture with the mixture of CCMP/CMP (2-chloro-5-chloromethylpyridine/2-chloro-5-methylpyridine) and the corresponding hydrochlorides.
Patent DK-1305440-T3 (DK)
Inventor: BIJL HENDRIK LOUIS
IPC: C07G99/00
Filed: 2001-08-01
Granted: 2010-09-13
Abstract: The extraction of a microbial or single cell oil, for example comprising one or more polyunsaturated fatty acids (PUFAs), directly from microbial cells is disclosed which avoids the need for solvents. After fermentation, the microbial cells are pasteurised, washed and the cell walls lysed or disrupted by a mechanical (e.g. homogenisation), physical (boiling or drying), chemical (solvents) or enzymatic (cell wall degrading enzymes) technique. The oil (containing the PUFA) is then separated from the resulting cell wall debris. This is achieved by centrifugation, which results in an oily phase (top layer) that contains the oil which that can be separated from an aqueous phase (containing the cell wall debris). The oil can then be extracted and if necessary the PUFA can be purified or isolated from the oil.
Patent DK-1295890-T3 (DK)
Inventor: HAMAMOTO SHOICHI
IPC: A61P31/12
Filed: 2001-02-14
Granted: 2005-05-17
Abstract: Pyrazine derivatives represented by general formula Ä1Ü: <CHEM> wherein the variables are as defined in the specification, or salts thereof have an excellent antiviral activity and are useful as a therapeutic agent for treating viral infections. Further, fluoropyrazine-carboxamide derivatives represented by general formula Ä2Ü: <CHEM> wherein the variables are as defined in the specification, or salts thereof are useful as an intermediate for production of the compounds of general formula Ä1Ü, and as an intermediate for production of the fluoropyrazine-carboxamide derivatives of which one typical example is 6-fluoro-3-hyroxy-2-pyrazine-carboxamide having an antiviral activity.
Patent DK-1322127-T3 (DK)
Inventor: VILLARET OLIVIER
IPC: H04M1/00
Filed: 2002-12-05
Granted: 2010-01-18
Abstract: The terminal has a liquid crystal screen with a serial (4) and a parallel interface (5), and is controlled by a control module (3). A microprocessor (1) drives control module of the screen and another microprocessor (2) handles other functions of the terminal. The terminal is characterized such that, in the standby mode one microprocessor is deactivated while the other drives the control module of the screen.
Patent DK-1355910-T3 (DK)
Inventor: GUPTA SHANKER
IPC: C07K5/065
Filed: 2002-01-25
Granted: 2011-06-27
Abstract: The present invention provides stable compounds prepared from boronic acid and lyophilized compounds thereof of formula (1) in which Z 1  and Z 2  are moieties derived from sugar. The invention also provides methods for preparing such compounds. Lyophilizing a mixture comprising a boronic acid compound and a moiety derived from sugar produces a stable composition that readily releases the boronic acid compound upon reconstitution in aqueous media.
Patent DK-1432407-T3 (DK)
Inventor: ROBERTS RONALD JOHN
IPC: A61K38/17
Filed: 2002-09-20
Granted: 2005-05-23
Abstract: The present invention relates to a pharmaceutical composition comprising lisinopril and dibasic calcium phosphate dihydrate (DCPD), produced by a process comprising mixing lisinopril and DCPD with a specific surface area of less than 1.5 m2g-1. The use of large particle sized DCPD in a lisinopril formulation/composition has the effect of reducing the amount of the lisinopril degradation product DKP that is formed, thereby increasing the shelf-life of tablets formulated with the larger sized DCPD, particularly those with low doses of lisinopril.
Patent DK-1331309-T3 (DK)
Inventor: MORLOCK MICHAEL J
IPC: B23K9/038
Filed: 1998-02-21
Granted: 2005-01-10
Abstract: The method of gas shielded arc welding steel railroad rails involves the steps of filling the base gap, the web gap and the head gap with a molten steel from a filler metal electrode by a gas shielded electric arc process. The filling of the head gap involves continuously sequentially moving the electrode in laterally opposite directions in the head gap along paths having starting and ending ends in the corresponding one of the opposite directions for laying beads of filler metal along the paths. Another step is delaying movement of the electrode from the starting end of each the path for a preselected period of time.
Patent DK-1546328-T3 (DK)
Inventor: SANDIG VOLKER
IPC: C12N5/10
Filed: 2003-10-06
Granted: 2006-08-07
Abstract: Preparing a cell capable of stable high yield expression of a target gene product comprising selecting a starting cell capable of stable high yield expression of a starting gene product (SGP) non-essential to the starting cell, screening for the locus of the SGP within the cell, and replacing the gene coding for the SGP with a DNA sequence containing one or more recombinase recognition sites to obtain a functionalized precursor cell, is new. Preparing a cell capable of stable high yield expression of a target gene product comprising selecting a starting cell capable of stable high yield expression of a starting gene product being non-essential to the starting cell, screening for the locus of the starting gene product within the genome of the starting cell, and replacing the gene coding for the starting gene product with a first functional DNA sequence containing one or more recombinase recognition sites (RRS) to obtain a functionalized precursor cell, is new. The method further comprises integrating a second functional DNA sequence containing a DNA sequence coding for the target gene product into the functionalized precursor cell obtained by use of recombinase recognizing the RRSs incorporated with the first functional sequence. The replacement step alternatively comprises directly replacing the gene coding for the starting gene product with a functional DNA sequence containing a DNA sequence coding for the target gene product. Independent claims are also included for: (1) a cell capable of high yield expression of a target gene product obtainable by the method cited above; (2) preparing a functionalized cell comprising the steps of the method cited above; (3) a functionalized cell by the method of (2); and (4) high yield expression of a target gene product which comprises cultivating a cell of (1).
Patent DK-1418170-T3 (DK)
Inventor: RODUIT JEAN-PAUL DR
IPC: C07B57/00
Filed: 1998-11-24
Granted: 2006-10-09
Abstract: Production of optionally (1S,4R)- or (1R,4S)-1-amino-4-(hydroxymethyl)-2-cyclopentene (VII) or (VIII) (or their salts) involves biotechnological optical resolution of racemic 1-amino-4-(hydroxymethyl)-2-cyclopentene (I) using a hydrolase in presence of an acylating agent. Production of (1S,4R)- or (1R,4S)-1-amino-4-(hydroxymethyl)-2-cyclopentene of formula (VII) or (VIII) (or their salts) involves biotechnological optical resolution of racemic 1-amino-4-(hydroxymethyl)-2-cyclopentene of formula (I) using a hydrolase (specifically a lipase) in presence of an acylating agent.X, Y=H or acyl. Independent claims are included for: (1) preparation of (VII; X, Y= H) or (VIII; X, Y= H) (or their salts) comprising chemical hydrolysis of corresponding compounds in which at least one of X and Y is other than H; and (2) production of (VII; Y= H; X= COR) or (VII; Y= H; X= COR) by (a) reducing 2-azabicyclo-(2.2.1)-hept-5-en-3-one (II) (in racemic or optical isomer form) to racemic (I); (b) carrying out biotechnological optical resolution (I) using a hydrolase in presence of an acylating agent to give (VII; X,Y= H) or (VII; X,Y= H); and (c) acylating to give (VII; Y= H; X= COR) or (VII; Y= H; X= COR). R : 1-4C alkyl, 1-4C alkoxy, aryl or aryloxy. [Image].
Patent DK-1442785-T3 (DK)
Inventor: AFNAN ALI MOHAMMAD
IPC: G01N21/35
Filed: 2001-02-12
Granted: 2006-09-25
Abstract: Mixing of components, e.g. pharmaceutical actives and excipients, is carried out while monitoring the spectroscopic profile of the mixture during the mixing process so that the spectroscopic profile may be used to determine the point at which mixing is terminated. In one embodiment of the invention, the spectroscopic data is collected by means of a monitoring unit mounted on the mixing vessel. the mixing vessel being mounted and driven so as to rotate or oscillate mounted and thereby effect mixing of its contents and the monitoring unit being mounted for rotation or oscillation with the vessel. When the spectroscopic data indicates that mixing has progressed to a desired state, e.g. the production of a homogeneous blend, the monitoring unit transmits a signal to the drive source to terminate rotation or oscillation of the vessel. <IMAGE>
Patent DK-1475145-T3 (DK)
Inventor: HIMMELSBACH WERNER DIPL-ING
IPC: B01F27/91
Filed: 2004-05-07
Granted: 2008-02-11
Abstract: A stirring unit has a number of stirring blades (14) where each has a section (20) bent forwards in the direction of rotation, at the trailing end of the blade and in a radially outer zone. The ratio of the radial length (L1) of the bent section to the total radial length (L2) of the stirring blade is 0.2-1.0 and preferably 0.4-0.6. The ratio of the width (B1) of the bent section to the total width (B2) of the stirring blade is 0.1-1.0 and preferably 0.15-0.4.
Patent DK-1622800-T3 (DK)
Inventor: NEUMANN JOACHIM
IPC: B60T13/68
Filed: 2004-04-24
Granted: 2007-02-26
Abstract: The invention relates to a braking device for a wind power plant. The wind power plant comprises a rotor (12) that converts wind energy into rotational motion. The rotor drives an electric generator (14) whose electrical power can be fed into an electrical power grid. The braking device contains a hydraulically actuated brake (21) for the rotor, a hydraulic valve (40), which controls the supply of pressure medium to the brake, and contains a regulating device (44) that produces a control signal for the hydraulic valve. In order to improve the behavior of the wind power plant during braking, a regulating device (44) is provided that has a control circuit for controlling the pressure of the pressure medium supplied to the brake. The output signal of a pressure sensor (23), which is subjected to the action of the pressure, is fed to the pressure control circuit. A pressure regulator forms the control signal for the hydraulic valve based on the difference of the pressure actual value from a pressure set value. The invention also relates to a method for operating said braking device.
Patent DK-1641434-T3 (DK)
Inventor: DYER ANN MARGARET
IPC: A61K9/16
Filed: 2004-07-02
Granted: 2009-04-06
Abstract: There is provided a powder formulation for nasal delivery including a protein having a molecular weight of 10 kDa or greater and chitosan or a derivative thereof or a salt of chitosan or a salt of a derivative of chitosan. Preferably the protein is human growth hormone.
Patent DK-1582543-T3 (DK)
Inventor: NIESTEN MEIKE DR
IPC: C08G18/72
Filed: 2005-03-19
Granted: 2008-03-03
Abstract: Solvent containing preparation (I) comprises 1-7% of free isocyanate (NCO) group, 20-70% of solid content, less than 0.2% of monomer content of toluol diisocyanate (TDI) and less than 2% of methylenediphenyl diisocyanate monomers, based on NCO groups containing prepolymers of TDI-isocyanurate polyisocyanate and diphenylmethandiisocyanate. Solvent containing preparation (I) comprises 1-7% of free isocyanate (NCO) group, 20-70% of solid content, less than 0.2% of monomer content of toluol diisocyanate (TDI) and less than 2% of methylenediphenyl diisocyanate monomers, based on NCO groups containing prepolymers of TDI-isocyanurate polyisocyanate and diphenylmethandiisocyanate (where at least one of the prepolymers is prepared by using ethylene oxide block containing polyetherdiols with an average molecular weight of 3000-4500 g/mol and an alkylene oxide containing 2-18 wt.% of ethylene oxide of total diols). Independent claims are also included for: (1) the preparation of (I); (2) moisture hardening coating medium comprising (I), optionally catalysts (for the acceleration of the reaction of the free NCO groups with moisture) and raw materials and additives; (3) coatings, adhesives and/or sealants obtained from (I); and (4) substrates coats comprising the moisture hardening coatings.
Patent DK-1819230-T3 (DK)
Inventor: JY WENCHE
IPC: A61K35/18
Filed: 2005-12-07
Granted: 2012-08-20
Abstract: Compositions comprising membrane-derived and synthetic microparticles that induce platelet aggregation and are useful for treating bleeding disorders, particularly those involving platelet dysfunction. Microparticles include endothelial derived microparticles (EMP), platelet derived microparticles (PMP), erythrocyte derived microparticles (RMP), and synthetic microparticles (SMP), and are used to treat disorders such as thrombocytopenia caused by chemotherapy.
Patent DK-1878822-T3 (DK)
Inventor: GANZONI STEFAN
IPC: D04B1/18
Filed: 2006-07-12
Granted: 2010-01-04
Abstract: The present invention relates to a method for assigning states to stitches of a fabric, wherein the state can vary between a first and a second state, that comprising the steps of a) allocating a part of the fabric (30), b) randomly assigning a state to each stitch of the allocated part of the fabric (31), c) evaluating the ratio between the number of stitches in the first state and the number of stitches in the second state (32), d) checking if the ratio lies within a predefined range of values (32), and e) restarting at step b) if the ratio lies outside the predefined range. The method may be used for manufacturing a medical compression garment.
Patent DK-1757252-T3 (DK)
Inventor: SUEHR SUSAN LYNN
IPC: A61F5/441
Filed: 2006-08-23
Granted: 2011-10-17
Abstract: A filter assembly for an ostomy pouch includes a composite microporous membrane, a filter and a connecting film for connecting the membrane to the ostomy pouch.
Patent DK-1896421-T3 (DK)
Inventor: DINSMORE CHRISTOPHER J
IPC: C07D221/16
Filed: 2006-06-22
Granted: 2012-01-09
Abstract: The present invention relates to 5H-benzo[4,5]cyclohepta[1,2-b]pyridine compounds, that are useful for treating cellular proliferative diseases, for treating disorders associated with MET activity, and for inhibiting the receptor tyrosine kinase MET. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.
Patent DK-2150699-T3 (DK)
Inventor: ANDERSEN BRIAN W
IPC: F03D7/02
Filed: 2008-04-30
Granted: 2011-01-31
Abstract: A method of operating a wind turbine with pitch control, in which values of the generated power and the operating speed of the rotor are established at a discrete number of secure ranges for wind speeds above a critical wind velocity. A wind turbine and a cluster of wind turbines employing such a method are also contemplated.
Patent DK-2158185-T3 (DK)
Inventor: NETT MARKUS
IPC: C07D231/12
Filed: 2008-06-13
Granted: 2011-11-21
Abstract: The present invention relates to a process for preparing 3-difluoromethyl-Substituted pyrazole compounds of the formula (I) in which R1 is H, halogen, nitro, C1-C8-alkyl, C1-C8-haloalkyl, C3-C8-cycloalkyl, phenyl, naphthyl, hetaryl, cyano, —C(═O)—OR1a, —C(═O)—NR1bR1c, —C(═O)—SR1d or —C(═S)—SR1e; R2 is H, C1-C4-alkyl, benzyl or phenyl; R3 is H, halogen, C1-C8-alkoxy, C1-C8-haloalkoxy, C3-C8-cycloalkoxy, C2-C8-alkenyloxy, C1-C8-alkylthio, C1-C8-haloalkylthio, C3-C8-cyclo-alkylthio or C2-C8-alkenylthio; compounds of the formula (II.a) or (II.b), in which R1 and R3 each have one of the definitions given above; R4 is halogen, —OR4a, —SR4a, —O—SO2—R4a or an —NR4bR4c group; R5 and R6 are each C1-C8-alkyl, C1-C8-haloalkyl, C3-C8-cycloalkyl, benzyl or phenyl, or, together with the nitrogen atom to which they are bonded, are a 3- to 8-membered heterocycle; Lewis acid adducts of compounds of the formula (II.b); the use of compounds of the formula (II.a) or (II.b) and of the Lewis acid adducts for preparing compounds of the formula (I) or (VI); and to a process for converting such compounds to the corresponding 3-difluoro-pyrazol-4-ylcarboxylic acids.
Patent DK-2304285-T3 (DK)
Inventor: PARKER CHRISTIAN
IPC: F16K11/22
Filed: 2009-06-09
Granted: 2012-07-23
Abstract: An expansion valve assembly is provided comprising a distributor body (30) having a liquid inlet (40), a port (34) having a selectively moveable pin (35) to allow liquid′ from the liquid inlet past the port, a gas inlet (50), a mixing chamber (32), and a plurality of circuits (60). The mixing chamber is positioned between the port and the plurality of circuits, the mixing chamber (32) having an axial centerline (A) that, is the axial centerline of the valve. The gas inlet has an axial centerline (B) that is off set from the axial centerline of the mixing chamber to promote a homogeneous gas/liquid mixture.
Patent DK-3024764-T3 (DK)
Title: Elevationstransportsystem
Inventor: MCSWAIN R KEVIN
IPC: E04G3/28
Filed: 2014-09-05
Granted: 2018-06-25
Abstract: An elevation conveyance system for transporting a payload substantially vertically and transversely to a preselected release location. The system includes a track assembly comprising a substantially vertical track, one or more bin assemblies in which the payload is receivable, and one or more car assemblies configured for movement along the track. The car assembly includes a housing subassembly having a means for engaging the track to permit movement of the car assembly along the track, and a conveyor subassembly for transporting the payload substantially transversely relative to the track. The bin assembly is receivable in the housing subassembly and configured to release the payload onto the conveyor subassembly for substantially transverse transportation of the payload to the preselected release location.
Patent DK-3105253-T3 (DK)
Inventor: CHINN YVONNE
IPC: C07K16/28
Filed: 2015-02-11
Granted: 2018-09-03
Abstract: The invention provides anti-Jagged1 antibodies and methods of using the same.
Patent DK-0422863-T3 (DK)
Inventor: SUTEHALL RALPH
IPC: G02B6/44
Filed: 1990-10-08
Granted: 1994-02-21
Abstract: An all-dielectric optical fibre cable comprises a strength member rod (1) having a roughened surface (1A) formed by a moulding process during manufacture of the rod using a woven tape imprint, which serves to improve adhesion between an extruded outer sheath (7) and the surface (1A) of the rod (1). The cable is suitable as an all dielectric aerial cable for large unsupported spans eg 500M, alongside a high voltage electricity distribution system.
Patent DK-0428352-T3 (DK)
Inventor: STEFANO FRANCISCO JOSE EVARIST
IPC: A61K31/54
Filed: 1990-11-12
Granted: 1995-12-27
Abstract: Pharmaceutical compositions for external use and their preparation are described wherein a specific, known non-steroid anti-inflammatory compound is homogeneously mixed with a pharmacologically acceptable vehicle that includes at least one component that has the ability to increase percutaneous permeability and which is selected from (C4-C30)fatty acids and alkyl and alkene esters thereof.
Patent DK-0433225-T3 (DK)
Inventor: CERLETTI NICO DR
IPC: C12R1/19
Filed: 1990-11-27
Granted: 1999-10-25
Abstract: The invention relates to a process for the production of biologically active, dimeric TGF- beta , to novel TGF- beta s and pharmaceutical compositions comprising it. TGF- beta produced by this process can be used in various therapeutic modalities.