baber/WOPTO huggingface dataset:
Patent MX-2007012222-A (MX)
Title: Methods for treating immune disorders associated with graft transplantation with soluble ctla4 mutant molecules.
Inventor: RUSNAK JAMES
IPC: A61K38/17
Filed: 2006-04-05
Abstract: The present invention provides use of soluble CTLA4 mutant molecules which bind with greater avidity to the CD80 and/or CD86 antigen than wild type CTLA4 or non-mutated CTLA4Ig in the treatment of immune disorders associated with graft transplantation.
Patent MX-2007012544-A (MX)
Title: Protein glycosylation.
Inventor: DAVIS BENJAMIN GUY
IPC: C07K1/107
Filed: 2006-04-06
Abstract: The present invention relates to methods for glycosylating a protein in which the protein is modified to include an alkyne and/or an azide group. The invention further relates to a protein glycosylated by these methods.
Patent MX-2007013124-A (MX)
Title: Additive for hydrocarbon fuel consisting of non-acidic inorganic compounds of boron and related processes.
Inventor: BAXTER EDWARD C JR
IPC: C10L10/02
Filed: 2006-04-21
Abstract: The present invention provides a fuel additive and a process for using and making the fuel additive. The fuel additive includes a non-acidic boron-containing salt in a carrier fluid. The fuel additive enhances combustion by increasing fuel efficiency or decreased pollutant output in an exhaust gas resulting from combustion of the fuel with the fuel additive.
Patent MX-2008000195-A (MX)
Title: Mixtures of reactive dyes and their use.
Inventor: TZIKAS ATHANASSIOS
IPC: C09D11/00
Filed: 2006-06-28
Abstract: Dye mixtures that comprise at least one dye of formula (1), together with at least one dye from the group of formulae (2), (3), (4) and (5), wherein the radicals have the definitions given in the claims, are suitable, with good build-up behaviour, for dyeing or printing cellulose-containing fibre materials, and yield dyeings having a deep shade and good fastness properties.
Patent MX-2008012658-A (MX)
Title: Kinase inhibitors.
Inventor: CHAN TIN-YAU
IPC: C07D403/14
Filed: 2007-03-28
Abstract: Disclosed is a compound of the formula and the pharmaceutically acceptable salts thereof. Also disclosed are methods of treating protein kinase mediatied diseases using the compound of formula (1.0). Also disclosed are methods of treating cancer using a compound of formula (1.0). The disclosed methods also include combination therapies wherein the compound of formula (1.0) is administered in combination with at least one addition pharmaceutically active ingredient.
Patent MX-2008013207-A (MX)
Title: Methods of treating hot flashes with formulations for transdermal or transmucosal application.
Inventor: SIMES STEPHEN M
IPC: A61K9/06
Filed: 2007-04-04
Abstract: The present invention relates to transdermal or transmucosal formulations, methods of use for preparing medicaments for treating hot flashes and methods for treatment thereof by administering such formulations for transdermal or transmucosal administration of estrogen. The formulations are effective at surprisingly low daily doses, preferably the lowest effective dose of estrogen to treat hot flashes, namely about 0.45 to about 0.6 mg of estrogen per day in a delivery vehicle that includes a C2 to C4 alkanol, a polyalcohol, and a permeation enhancer of monoalkyl ether of diethylene glycol. The amount of estrogen which is administered produces an estimated nominal daily estrogen dose in a subject undergoing treatment of from about 10 to about 15 micrograms, and a serum estradiol level of between about 25 pg/ml to about 50 pg/ml.
Patent MX-2008013618-A (MX)
Title: Oral care regimen.
Inventor: PRENCIPE MICHAEL
IPC: A61Q11/00
Filed: 2007-05-07
Abstract: The invention includes methods of cleaning an oral surface, maintaining oral health and/ or increasing oral health. Such methods encompass contacting an oral surface with a primary oral care composition at least once daily, and contacting the oral surface with a periodic oral care composition at least once within a period of about 42 days. The periodic oral care compositions suitable for use in the method comprise a first abrasive having an Einlehner hardness of greater than about 5 mg loss per 100,000 revolutions and a second abrasive having an Einlehner hardness of less than about 5 mg loss per 100,000 revolutions. In the periodic oral care compositions, the ratio of the first abrasive to the second abrasive is about 1:1.6 to about 1.6:1. The periodic oral care compositions are characterized by a pellicle cleaning ratio of greater than about 100 and a radioactive dentin abrasion of less than about 200. Additionally or alternatively, the methods may include those where the second abrasive comprises silica and has an oil of absorption of greater than about 90 cm3/100g and/ or an Einlehner hardness of less than about 5 mg loss per 100,000 revolutions. The ratio of the first abrasive to the second abrasive may be about 1:1.6 to about 1.6:1. The total amount of the first and second abrasives present in the oral composition may be greater than about 25 % by weight of the composition and/ or the oral composition has a pellicle cleaning ratio of greater than about 100 and a radioactive dentin abrasion of less than about 200.
Patent MX-2009001452-A (MX)
Title: Peptides having pharmacological activity for treating disorders associated with altered cell migration, such as cancer.
Inventor: PAVONE VINCENZO
IPC: A61K38/03
Filed: 2007-07-19
Abstract: Peptides and their functionally equivalent derivatives, in salified or non-salified form, with the general formula L1-X1-X2-X3-X4 , wherein: L1 is H, or acyl, or any natural or non-natural amino acid, optionally N-acylated, N-alkylated and/or CÎ±-alkylated; X1 and X3, which are equal or different, are any natural or non-natural basic amino acid, optionally N-alkylated and/or CÎ±-alkylated; X2 is any natural or non-natural amino acid, optionally N-alkylated and/or CÎ±-alkylated, with the proviso that it is not glycine and amino acids mono-substituted on the Î± carbon atom with a linear or cyclic alkyl group, from 1 to 10 carbon atoms, and amino acids mono-substituted on the Î± carbon atom with a linear or cyclic alkyl group containing 4 to 10 carbon atoms, or amino acids mono-substituted on the Î± carbon atom with an alkyl group containing 1 to 8 carbon atoms, optionally substituted with a carbamoyl, hydroxyl or aromatic group; X4 is any natural or non-natural hydrophobic amino acid, optionally CÎ±-alkylated and/or amidated at the C-terminal end, or any hydrophobic amino alcohol, or a hydrophobic <i>gem</i>-diamine, optionally N'-alkylated or N'-acylated.
Patent MX-2009004611-A (MX)
Title: Formulations of phospholipase enzyme inhibitors.
Inventor: KU MANNCHING SHERRY
IPC: A61K47/00
Filed: 2007-10-30
Abstract: The present invention is directed to formulations of inhibitors of phospholipase enzymes, such as cytosolic PLA2, compositions containing the same and processes for manufacture thereof.
Patent MX-2009005152-A (MX)
Title: Catalyst systems and polymerization processes.
Inventor: TERRY KERSTEN A
IPC: C08F4/00
Filed: 2007-11-13
Abstract: A method of polymerizing olefins with catalyst systems, such as, for example, a multimodal catalyst system, wherein the catalyst system is stored at a controlled temperature to minimize loss of catalyst system productivity.
Patent MX-2009005395-A (MX)
Title: Flow controller.
Inventor: JEDWAB MICHAEL
IPC: A61M39/28
Filed: 2007-11-05
Abstract: A device for controlling the rate of flow of a liquid in a flexible tube comprising two opposed surfaces between which the tube is received in use wherein the surfaces are elongated in the direction of flow of the liquid in the tube and are either parallel to one another or arranged so that in use the included angle does not exceed 40Â°, and means for varying the distance between the surfaces so as to compress the tube between them by the desired amount.
Patent MX-2009007914-A (MX)
Title: Novel pharmaceutical compositions.
Inventor: ALVARO GIUSEPPE
IPC: A61K31/00
Filed: 2008-01-21
Abstract: The present invention relates to pharmaceutical compositions comprising an NK1 receptor antagonist and a sodium channel blocker compound of formula (I) wherein R1 and R2 are independently hydrogen, C1-6alkyl or C3-6cycloalkyl1-6galkyl; or R1 and R2, together with the nitrogen to which they are attached, may form an unsubstituted 3-, 4-, 5- or 6-membered saturated ring; q is 1 or 2; R3 and R4 are hydrogen; or when q is 1, R3 and R4, together with the interconnecting atoms, may form a cyclopropane ring; X is carbon or nitrogen; n is 0, 1 or 2, wherein when present each R5 is independently selected from the list consisting of C1-3alkyl, halogen, cyano, haloC1-3alkyl, hydroxy, C1-3alkoxy and C1-3haloalkoxy; and either R6 or R7 is -O-R8 or -OCH2R8, wherein the other R6 or R7 is hydrogen or R5; and wherein R8 is either a phenyl ring or a 5- or 6-membered aromatic heterocyclic ring (independently containing one or more nitrogen, sulphur or oxygen atoms) wherein either the phenyl ring or the heterocyclic ring is optionally substituted by one or more groups independently selected from the list consisting of C1-3alkyl, halogen, cyano, haloC1-3alkyl, hydroxy, C1-3alkoxy and C1-3haloalkoxy; or a pharmaceutically acceptable salt or solvate thereof; as a combined preparation for simultaneous or sequential administration, and to the use of such compositions in the treatment of certain disorders, including epilepsy and mood disorders.
Patent MX-2009009402-A (MX)
Title: Ion mobility spectrometers.
Inventor: ATKINSON JONATHAN RICHARD
IPC: H01J49/00
Filed: 2008-03-06
Abstract: An ion mobility spectrometer has a reaction region (5) separated from a drift region (20) by an electroststic gate (21). A doping circuit (8) supplies a dopant to the reaction region (5) but the drift region (20) is undoped. Two high field ion modifiers (30 and 31) are located one after the other in the drift region (20). One modifier (30) can be turned on to remove dopant adducts from the admitted ions or both (30 and 31) can be turned on so that the ions are also fragmented. In this way, several different responses can be produced to provide additional information about the nature of the analyte substance and distinguish from interferents.
Patent MX-2009011855-A (MX)
Title: Mr methods of grading a tumor using an imaging medium that comprises hyperpolarised 13c-pyruvate.
Inventor: HURD RALF EUGENE
IPC: A61B5/055
Filed: 2008-05-16
Abstract: The application relates to MR methods of grading a tumor using an imaging medium which comprises hyperpolarized 13C-pyruvate. In particular, it relates to a method of determining the grade of a tumor, said method comprises a) MR detecting a tumor in a subject using an imaging medium that comprises hyperpolarized13C-pyruvate wherein signals of 13C-pyruvate and its 13C-containing metabolites alanine, lactate and optionally bicarbonate are detected; b) using said signals and optionally the total carbon signal to generate a metabolic profile of the tumor; c) comparing the metabolic profile of the tumor generated in step b) to a known metabolic profile of a tumor of a certain grade; and d) determining the grade of the tumor based on the similarities and differences between said metabolic profile of the tumor and said known metabolic profile.
Patent MX-2009011918-A (MX)
Title: Imaging technique.
Inventor: MCGRATH DEIRDRE
IPC: A61B5/08
Filed: 2008-04-18
Abstract: The present invention relates to a method of characterising lung function in a subject in need of such characterisation. The method comprises performing an imaging technique, on a voxel defined within a lung space of interest. Image data is generated over a time period during which the subject inhales gases with at least two different partial pressures of a paramagnetic gas. A compartmental model algorithm is applied to the image data generated for the voxel to provide information on ventilation, diffusion and perfusion of a lung. The paramagnetic gas is preferably Oxygen. The imaging technique is preferably Oxygen Enhanced Magnetic Resonance Imaging (OE-MRI).
Patent MX-2009012318-A (MX)
Title: Method for liquid control in multiphase fluid pipelines.
Inventor: HOLM HENNING
IPC: F17D1/00
Filed: 2008-04-28
Abstract: A method for the control of liquid or liquid slugs in multi phase fluid pipelines, including a multiphase pipeline (1) for the transportation of a fluid, consisting of mainly gas and some liquid such as water an/or gas condensate. The gas is evacuated via a gas separation unit (4) being connected to the multiphase pipeline (1) to a second gas transport pipe (5), whereas the liquid is fed to a dedicated pipeline section acting as a buffer volume pipeline (7), preferably provided as a continued part of the multiphase pipeline (1). The separation unit (4) includes one or preferably several vertical pipes (6) connected at a distance from one another along the multiphase pipeline (1), whereby the gas is transported separately to a downstream processing facility on a platform or onshore (3) or the like, and whereby the liquid proceeds to the loop (7) which may preferably be an extension of the multiphase pipeline, or the liquid and gas may be re-combined and led in a common transport pipeline to the desired destination.
Patent MX-2009013778-A (MX)
Title: Apparatus and methods for automatic insertion, debubbling, cleaning and calibration of a spectral probe during dissolution testing.
Inventor: CHIN LAURENCE DWAYNE
IPC: G01N33/15
Filed: 2008-06-18
Abstract: A dissolution test apparatus includes an optical probe, an automated actuator. The probe takes an optics-based measurement in dissolution media contained in a test vessel and transmits the measurement to an analytical instrument situated remotely from the vessel. The optical probe is movable by the actuator into and out from the vessel. The dissolution test apparatus may include a bubble removal apparatus that communicates with the optical probe and is configured for transmitting a variable vibrating force to the probe, wherein bubbles are removed from a light path gap of the probe. In another dissolution test apparatus, the bubble removal apparatus rotates the probe to remove bubbles. Another dissolution test apparatus includes a movable cleaning mechanism, a movable calibration mechanism, or both mechanisms.
Patent MX-2010003687-A (MX)
Title: Coupling device.
Inventor: CERASOLI PAOLO
IPC: A61M39/18
Filed: 2008-10-02
Abstract: A coupling device (1) for connecting two ends (3, 9) of respective tubular members, allow the opening and the closing of a first tubular member and the simultaneous engagement of the two tubular members, in such a way preventing any pollution, comprises: a first case (5) housing a first end (3) of a respective first tubular member (2), comprising closing means (10) of said first end (3); a second case (20), wherein a flexible terminal section (6) of a respective second tubular member is received, comprising means for driving a second end (9) of said second tubular member from a retracted position to a engagement position into said first end (3) and vice versa; and means for reversibly connecting said first and second cases (5, 20) at a respective coupling port thereof, defining a single sealed environment; wherein the engagement and the disengagement of said second end (9) and the automatic mechanical activation and deactivation of said closing means (10) for opening and closing said first end (3).
Patent MX-2010005044-A (MX)
Title: Method for providing tissue products having coordinated decor features.
Inventor: WALTHER RACHAEL EDEN
IPC: G06Q10/00
Filed: 2008-10-29
Abstract: A method of customizing a tissue product, having the steps of: selecting a plurality of different architectural decor or home decor styles; categorizing the architectural decor or home decor styles into style groups; selecting a plurality of style groups; selecting at least one design that is representative of each style group; applying the selected designs to one or more tissue products, so that the tissue products represent the style group.
Patent MX-2010007076-A (MX)
Title: Nanodispersion.
Inventor: BHOWMICK SUBHAS BALARAM
IPC: A61K9/51
Filed: 2008-12-23
Abstract: The present invention provides a nanodispersion comprising nanoparticles having a mean size less than 300 nm dispersed in a vehicle comprising a water miscible solvent and water, said nanoparticles comprising one or more taxane derivative, a polymer and a surfactant comprising a mixture of fatty acids or its salts and sterol or its derivatives or its salts.
Patent MX-2010007679-A (MX)
Title: Herbicidal compounds.
Inventor: TURNBULL MICHAEL DRYSDALE
IPC: A01N43/90
Filed: 2009-01-16
Abstract: The present invention relates to a method of controlling plants or inhibiting plant growth which comprises applying to the plants or to the locus thereof a herbicidally effective amount of a compound of formula (I) wherein R1, R2, R3, R4 and R5 are as defined in claim 1; or a salt or TV-oxide thereof. Furthermore, the present invention relates to processes for preparing compounds of formula (I), to intermediates used in the preparation of compounds of formula (I), to herbicidal compositions comprising compounds of formula (I) and to certain novel pyridopyridines.
Patent MX-2010009511-A (MX)
Title: Novel 7-substituted derivatives of 3-carboxy-oxadiazino-quinolone s, preparation thereof and use thereof as anti-bacterial agents.
Inventor: CIAPETTI PAOLA
IPC: C07D498/06
Filed: 2009-02-26
Abstract: The invention relates to compounds of the formula (I) in which: - either R1 is H, OH, NH2, -(CH2)m - NRaRb (m = 0,1 or 2), Ra and Rb are H, linear, branched or cyclic (l-6c) alkyl, (3-6c) cycloalkyl - (1-6c) alkyl, Rc, S(O)2Rc, C(O)Rc, S(O)2Rd or C(O)Rd; or Ra and Rb form with N an Rc radical; Rc is an optionally substituted, saturated, unsaturated or aromatic cycle with 5 or 6 vertexes and containing from 1 to 4 heteroatoms selected from N, O and S; Rd is linear, branched or cyclic (l-6c) alkyl optionally substituted by 1 to 4 halogens; or R1 is Rc or CHReRc or CHReRd; Re is H, OH, NH2, (1-6c) NHaIk or (1-6c) NaIk2, or (1-7c) NH-acyl or NHRc; R2 is H, (CH2)m-NRaRb, Rc, CHReRc or CHReRd, and R'2 is H; provided that R1 and R2 cannot be H simultaneously or that R1 and R2 or R2 and R1 cannot be one (CH2)m-NRaRb or Rc or H and the other OH, or one H and the other NH2, or one H and the other (CH2)m-NRaRb,, Ra and Rb being H or alkyl or C(O) Rd, Rd being a non-substituted alkyl or cycloalkyl; - either R1 is such as defined above except for hydrogen and R2 and R'2 are gem (1-6c) dialkyl or alkyl (1-6c)-oxime, or R2 and R'2 are Rc or Rd and OH, NH2, NHRc or NHRf, Rf being a (l -7c) acyl; - or R1 is Hydrogen and R2 and R'2 are together (1-6c)-oxime alkyl or are one Rc and the other OH, NH2, NHRc or NHRf; n is 0 or 1; R3 and R'3 are H or (1-6c) alkyl optionally substituted by 1 to 3 halogens or R3 is (1-6c) alkoxy carbonyl and R'3 is H; R4 is methyl optionally substituted by halogen; R5 is H, (1-6c) alkyl or (7- 12c) arylalkyl; R6 is H, Fluorine, NO2, CF3 or CN. The invention also relates to said compounds in their enantiomer form or mixtures thereof, as well as to their salts with acids and bases, to their preparation, and to the use thereof as anti-bacterial agents, both in human or veterinary medicine.
Patent MX-2010009919-A (MX)
Title: Methods of uplink channelization in lte.
Inventor: ZHANG JIANZHONG
IPC: H04L27/26
Filed: 2009-03-13
Abstract: Methods of a slot-level remapping physical uplink control channels into two resource blocks respectively located at two slots of a subframe, are generally adapted to a 3GPP LTE physical uplink where ACK/NAK resource blocks may be applied by the extended cyclic prefix, adapted to a complex 3GPP LTE physical uplink where mixed resource blocks (where the ACK/NAK and CQI channels coexist) may be applied by the normal cyclic prefix, and adapted to a complex 3GPP LTE physical uplink where mixed resource blocks (where the ACK/NAK and CQI channels coexist) may be applied by the extended cyclic prefix.
Patent MX-2011004203-A (MX)
Title: Foldable container for holding a pourable product.
Inventor: OUILLETTE PAUL
IPC: B65D77/06
Filed: 2009-10-01
Abstract: A container (100) is disclosed. The container may include a fillable bladder (104) in an interior of an enclosure (102) of the container. The container (100) may be used for packaging a pourable product into a fillable bladder (104) while the fillable bladder is positioned inside the container. The container may include an enclosure (102) having a blind depth recess bottom handle (198). The container may include an enclosure (102) having a bottom flap having a flap perimeter which generally matches a lower perimeter of a plurality of sides of the enclosure.
Patent MX-2011005382-A (MX)
Title: Isoform specific anti-her4 antibodies.
Inventor: SLIWKOWSKI MARK X
IPC: C07K16/32
Filed: 2009-11-24
Abstract: Compositions and methods useful for detecting and treating cancers which express the HER4 JM-a isoform are disclosed.
Patent MX-2011006575-A (MX)
Title: Aminopyridine and carboxypyridine compounds as phosphodiesterase 10 inhibitors.
Inventor: CHEN NING
IPC: C07D213/74
Filed: 2009-12-16
Abstract: Pyridine and pyrimidine compounds: (I); or a pharmaceutically acceptable salt thereof, wherein m, n, R<sup>1</sup>, R<sup>2</sup>, R<sup>3</sup>, R<sup>4</sup>, R<sup>5</sup>, R<sup>6</sup>, R<sup>7</sup>, X<sup>1</sup>, X<sup>2</sup>, X<sup>3</sup>, X<sup>4</sup>, X<sup>5</sup>, X<sup>6</sup>, X<sup>7</sup>, X<sup>8</sup>, and Y are as defined in the specification; (II); or a pharmaceutically acceptable salt thereof, wherein ring A, m, n, y, R<sup>2</sup>, R<sup>3</sup>, R<sup>4</sup>, R<sup>5</sup>, R<sup>6</sup>, R<sup>7</sup>, R<sup>8</sup>, R<sup>9</sup>, X<sup>1</sup>, X<sup>2</sup>, and ring A are as defined in the specification; and (III); or a pharmaceutically acceptable salt thereof, wherein m, n, y, R<sup>2</sup>, R<sup>3</sup>, R<sup>4</sup>, R<sup>5</sup>, R<sup>6</sup>, R<sup>7</sup>, R<sup>9</sup>, X<sup>1</sup>, X<sup>2</sup>, and ring A are as defined in the specification; compositions containing them, and processes for preparing such compounds. Provided herein also are methods of treating disorders or diseases treatable by inhibition of PDE10, such as obesity, non-insulin dependent diabetes, schizophrenia, bipolar disorder, obsessive-compulsive disorder, and the like.
Patent MX-2011007898-A (MX)
Title: Incorporation of dye into granular laundry composition.
Inventor: BATCHELOR STEPHEN NORMAN
IPC: C11D3/34
Filed: 2010-01-08
Abstract: The present invention concerns a shading dye containing granule.
Patent MX-2011009654-A (MX)
Title: Method for therapeutic use.
Inventor: PFEIFER ANDREA
IPC: A61P25/28
Filed: 2010-03-18
Abstract: The present invention is related to methods for the therapeutic use in the treatment of diseases and disorders where T-helper independent antibody responses are beneficial. In particular, the present invention relates to a method wherein these diseases and disorders above are treated in immunocompromised or autoimmune diseased animals or humans. Even more particular the present invention relates to the treatment of Alzheimer's disease in immunocompromised or autoimmune diseased animals or humans or where inflammatory reactions need to be specifically avoided.
Patent MX-2011009734-A (MX)
Title: Novel method for producing enaminocarbonyl compounds.
Inventor: LUI NORBERT
IPC: C07D405/12
Filed: 2010-03-12
Abstract: The invention relates to a method for producing enaminocarbonyl compounds of formula (I), according to which compounds of formula (II) are reacted in the presence of a BrÃ¸nsted acid to form compounds of formula (I) and A, R1 and Z are defined as cited in the description. The invention also relates to corresponding parent compounds that are used in the claimed method.