baber/WOPTO huggingface dataset:
Patent CA-2286590-A1 (CA)
Title: Multifunctional polymeric tissue coatings
Inventor: HUBBELL JEFFREY A
IPC: B32B15/04
Filed: 1998-04-17
Abstract: Compositions for coating biological and non-biological surfaces, which minimize or prevent cell-cell contact and tissue adhesion, and methods of preparation and use thereof, are disclosed. Embodiments include polyethylene glycol/polylysine (PEG/PLL) block or comb-type copolymers with high molecular weight PLL (greater than 1000, more preferably greater than 100,000); PEG/PLL copolymers in which the PLL is a dendrimer which is attached to one end of the PEG; and multilayer compositions including alternating layers of polycationic and polyanionic materials. The multi-layer polymeric material is formed by the ionic interactions of a polycation and a polyanion. The molecular weights of the individual materials are selected such that the PEG portion of the copolymer inhibits cellular interactions, and the PLL portion adheres well to tissues. The compositions and methods are useful, for example, in inhibiting formation of post-surgical adhesions, protecting damaged blood vessels from thrombosis and restenosis, and decreasing the extent of metastasis of attachment-dependent tumor cells. The compositions and methods are also useful for coating non-biological surfaces such as metallic surfaces.
Patent CA-2287149-A1 (CA)
Title: Process for intensifying fast plug flow reactions using a high intensity tubular reactor
Inventor: CHENG ALAN TAT YAN
IPC: B01J19/24
Filed: 1999-10-19
Abstract: A process for intensifying fast plug flow reactions between a gas and a liquid using a high intensity tubular reactor based on supersonic two-phase flow principles under high pressure.
Patent CA-2288198-A1 (CA)
Title: Modulation of vascular healing by inhibition of leukocyte adhesion and function
Inventor: EDELMAN ELAZER R
IPC: A61K38/00
Filed: 1998-03-25
Abstract: Compounds that specifically inhibit or reduce leukocyte adhesion or function are useful to enhance vascular healing and lessen restenosis of blood vessels after revascularization, via angioplasty or bypass surgery, of diseased coronary, peripheral and cerebral arteries, and lessen stenosis or restenosis of surgically-placed bypass grafts and transplanted organs. Examples of these compounds are those which block cell surface integrins or their ligands, for example, the leukocyte integrin Mac-1 (CD11b/CD18, .alpha.M.beta.2). As demonstrated by the examples, both superficial and deep injury was significantly reduced with treatment using an antibody to Mac-1 compared to both saline controls and IgG controls. After balloon angioplasty (superficial injury) neointimal area was reduced nearly 70 %. The ratio of intimal:medial area, which is customarily used in balloon-injured experimental arteries to normalize for small normal variations in arterial size from one animal to another, was reduced over 75 %. After endovascular stent implantation (deep injury) neointimal area was reduced nearly 40 %. Extrapolated to humans, this reduction in the intimal thickening would reduce restenosis from occuring in approximately 30 % of patients to less than 10 % of patients.
Patent CA-2288267-A1 (CA)
Inventor: LEES ANDREW C
IPC: A61P31/04
Filed: 1998-04-23
Abstract: L'invention porte sur un procédé de préparation d'un conjugué, et de préférence d'un conjugué protéine-polysaccharide, ce procédé consistant à fonctionnaliser une première fraction (telle qu'un polysaccharide) avec un ou plusieurs groupes haloacyle pendants. La première fraction fonctionnalisée est ensuite mise à réagir avec une seconde fraction, de préférence, une protéine non modifiée ou une protéine à laquelle n'ont pas été ajoutés des groupes non thiol, de façon à former un conjugué lié de manière covalente. Divers réactifs haloacyle peuvent être utilisés dans cette invention. Par exemple, ce réactif haloacyle peut être un ester actif, un anhydride, un chlorure d'haloacyle ou un acide d'haloacyle. Les réactifs haloacyle spécifiques pouvant être utilisés dans ce procédé sont N-succinimidyl-2,3-dibromopropionate et N-succinimidyl iodoacétate. L'invention porte également sur des conjugués produits selon ce procédé et qui peuvent être utilisés comme immunogènes ou vaccins, ainsi que sur un procédé d'induction d'une réponse immune chez un sujet, procédé consistant à administrer un vaccin produit selon le procédé de cette invention.
Patent CA-2289995-A1 (CA)
Inventor: CASTELLA JEAN-PIERRE
IPC: H04B15/00
Filed: 1998-05-12
Abstract: An electromagnetic and/or electric interference suppression device that reduces the severity of electromagnetic and/or electric interference of an asymmetric system. The suppression device utilizes an antenna to develop a voltage that is ideally equal to the interference voltage developed from interference signals. A tuned circuit having two opposing diodes, a capacitor, and an inductor mounted in series with each other, to create a voltage that approximates as closely as possible, the interference voltage, neutralizing its effect on an asymmetric system.
Patent CA-2293480-A1 (CA)
Title: 2-aminoalkylaminoquinolines as dopamine d4 ligands
Inventor: HE XIAO-SHU
IPC: A61P25/18
Filed: 1998-06-11
Abstract: A compound of formula (IA) or the pharmaceutically acceptable acid addition salts thereof wherein: R1, R2, R3, R4 and R5 are the same or different and represent hydrogen, halogen, C1-C6alkyl, C1-C4alkoxy, C1-C4alkylthio, hydroxy, amino, mono(C1-C6) alkylamino, di(C1-C6)alkylamino, cyano, nitro, trifluoromethyl or trifluoromethoxy; R6 is hydrogen or C1-C6alkyl; W is nitrogen, COH, or CH; Y and Z independently represent nitrogen or CH; and A represents an alkylene group of from 2-5 carbon atoms optionally substituted with one or more alkyl groups having from one to four carbon atoms. The compounds of the invention demonstrate high affinity and selectivity in binding to the D4 receptor subtype.
Patent CA-2295620-A1 (CA)
Title: 5,6-heteroaryl-dipyrido¬2,3-b:3',2'-f|azepines and their use in the prevention or treatment of hiv infection
Inventor: KAPADIA SURESH R
IPC: C07D471/14
Filed: 1998-08-11
Abstract: Disclosed are novel heteroaryl-dipyridoazepines. These are useful in the prevention or treatment of HIV infection.
Patent CA-2295850-A1 (CA)
Title: Method for treating gases to reduce nitrogen oxide emissions using a catalytic composition based on silica and titanium oxide
Inventor: HEDOUIN CATHERINE
IPC: B01J35/00
Filed: 1998-07-01
Abstract: The invention concerns a method for treating gases to reduce nitrogen oxide emissions wherein a catalytic composition containing a catalytic phase on a support is used, characterised in that the support is based on silica and titanium oxide in an atomic proportion Ti/Ti+Si ranging between 0.1 and 15 %. The method is particularly useful for treating exhaust gases of diesel engines or of engines using a weak mixture.
Patent CA-2296185-A1 (CA)
Inventor: LUDWIG LESTER F
IPC: H04N7/15
Filed: 1994-10-03
Abstract: A teleconferencing/videoconferencing system has (1) a plurality of AV device, each capable of originating and reproducing user related audio and video signals; (2) a plurality of communications ports, each supporting the switch connections of video in, video out, audio in, and audio out; and (3) a communication path arranged for transport of audio and video signals. The system controls communications, over the communications path, between two of the AV devices by creating a first and second call handles, respectively associated with the two AV devices. Each call handle defines a call state (Either active and/or hold), and the AV device's port's switch connections involved in the communication connection. The system also allows a user to remotely put another caller on hold or remotely disconnect another caller.
Patent CA-2298295-A1 (CA)
Title: Wireless network using high and low decision thresholds for selecting and maintaining a channel
Inventor: ISHII KENICHI
IPC: H04W84/12
Filed: 2000-02-11
Abstract: In a communication network, a wireless channel is selected from multiple channels. The interference level of the selected channel is determined and a first quality value is derived and compared to a first decision threshold. If the first quality value is smaller than the first decision threshold, the selected channel is abandoned and a new channel is searched. If the first quality value is greater than the first decision threshold, the selected channel is maintained for transmission of a packet. A second quality value of the maintained channel is continuously determined and compared to a second decision threshold which is lower than the first decision threshold. Only if the second quality value is smaller than the second decision threshold, the channel is abandoned and a channel search is initiated.
Patent CA-2299316-A1 (CA)
Inventor: BERN SARA
IPC: H04W88/18
Filed: 1998-08-07
Abstract: In a communication network (N), an information message transfer means (IMTM) handles the independent forwarding of information messages to subscriber stations (A, B). When an initial call set-up request initiated from a first subscriber station (A) fails, this is detected by a detection means (DET). The information message transfer means (IMTM) is then activated and the first subscriber station (A) records a desired information message in a memory (MEM). Then the first subscriber station (A) goes into a "hung-up" operation state and is free for carrying on with other call set-up requests. The recorded information message is then transferred to the second subscriber station (B) by the information message transfer means (IMTM) which sets up an independent call to the desired subscriber station (B). With the independent setting-up of a call, it can be made sure that the information message will eventually reach the second subscriber station (B) without assistance of the first subscriber station (A).
Patent CA-2301106-A1 (CA)
Inventor: ZANGI KAMBIZ C
IPC: H04B1/66
Filed: 1998-08-27
Abstract: A channelizer for processing a wideband signal to extract a plurality of narrowband signals is disclosed. The channelizer is capable of processing a received wideband signal to extract a plurality of regularly spaced narrowband signals therefrom. The wideband signal is processed in such a manner that the extracted narrowband signals have a sampling frequency that is not limited to an integer multiple of the channel spacing and is valid for any combination of downsampling factors and number of channels.
Patent CA-2301778-A1 (CA)
Title: Jet propulsion boat
Inventor: FUJIMOTO KATSUMI
IPC: B63H11/11
Filed: 2000-03-21
Abstract: To provide a technique capable of improving the operability of a jet propulsion boat. A jet propulsion boat 10 includes a link mechanism 35 for driving a water reversing cup 32; a going-astern/slowing-down lever 42 for pushing/withdrawing the link mechanism 35; an operating force measuring means 45 for measuring an operating force applied to the going-astern/slowing-down lever 42, which is provided on the link mechanism 35 or going-astern/slowing-down lever 42; and a propulsion force control means 50 for controlling a water jetting force on the basis of the operating force measured by the operating force measuring means 45. Accordingly, the two-stage operations, that is, the operation to shift the water reversing cup 32 to the position facing to the outlet 23a of the nozzle 23 and the operation to control the water jetting force can be performed only by operating the going-astern/slowing-down lever 42.
Patent CA-2304203-A1 (CA)
Inventor: POIRIER JEAN-ERIC
IPC: E01F9/04
Filed: 1999-07-21
Abstract: La présente invention concerne un accélérateur de temps de séchage d'une peinture aqueuse comprenant des particules minérales, un liant polymère en dispersion aqueuse et un agent de polymérisation en émulsion, ainsi que la peinture correspondante. L'accélérateur a une structure polymérique, est hydrosoluble et comporte des charges cationiques. L'invention concerne également un procédé d'application sur un support d'une peinture aqueuse conforme à l'invention, selon lequel on pulvérise la peinture sur le support, on distribue des billes réfléchissantes dans la peinture et on incorpore dans la peinture, préférentiellement après la distribution des billes, l'accélérateur de temps de séchage. Application au marquage routier.
Patent CA-2304435-A1 (CA)
Inventor: TOETSCHINGER MARK
IPC: F04B53/04
Filed: 2000-04-05
Abstract: The alarm mechanism of the invention signals the absence of a liquid from a source of aqueous liquid. The alarm mechanism comprises an alarm body having an inlet port and an outlet port; the inlet port in liquid communication with a source of liquid, the outlet port in liquid communication with a use locus. The alarm mechanism additionally comprises a float chamber placed in liquid parallel communication with the inlet port and the outlet port. The float chamber contains a float operably connected to a mechanical alarm. The float, as the chamber is emptied of liquid, reaches a position wherein a "low or empty product" signal is generated. The apparatus operates by passing liquid through the body. As liquid in the source of liquid is depleted and is no longer available for passage through the body, the body becomes emptied of liquid as the source of pressure removes liquid from the body and particularly from the chamber causing the float to reach a position generating a signal.
Patent CA-2304742-A1 (CA)
Title: Ultrasound imaging guidewire with static central core and tip
Inventor: WHITE DAVID A
IPC: A61M25/09
Filed: 1998-09-23
Abstract: This invention is an ultrasound imaging guide wire (10) that is inserted into a patient's body. The guide wire has a static central core (20), and an imaging guide wire body (12) comprising an acoustical scanning device (18). The acoustical scanning device (18) can be rotated to obtain 360 degree acoustical images of a site of interest in the patient's body. Furthermore, the imaging guide wire (10) includes a connector (26) that permits the imaging guide wire body (12) to be disengaged from the static central core tip (14, 20) so that the imaging guide wire body can be axially translated to obtain multi-position imaging.  The imaging guide wire body (12) is axially translated without losing the original guide wire positioning because the static central core (20) maintains its position in the patient's body.
Patent CA-2304849-A1 (CA)
Title: Bisethers of 1-oxa, aza and thianaphthalen-2-ones as phospholamban inhibitors
Inventor: KARJALAINEN ARTO
IPC: A61K31/4704
Filed: 1998-09-24
Abstract: Therapeutically active compounds of formula (I) or (II), in which R1 is hydrogen, alkyl, alkenyl, aryl, arylalkyl, hydroxyalkyl, halogenalkyl, alkoxy, COR10, CONR10R11, OR10, S(O)mR10, NR10COR11 or NR10R11, where R10 is hydrogen, alkyl, alkenyl, aryl, arylalkyl, hydroxyalkyl, halogenalkyl, alkoxy or hydroxy and R11 is hydrogen, alkyl, aryl, arylalkyl, alkoxy, aryloxy, hydroxy or acyl, or in case where X is NR11, R1 can also be carboxylalkyl; R6 is hydrogen, alkyl, alkenyl, aryl, arylalkyl; R2 and R7 mean hydrogen, alkyl, aryl, arylalkyl, alkenyl, COR10, CONR10R11, halogen, trifluoromethyl, nitro or cyano, where R10 and R11 are defined as above; R3 is hydrogen, alkyl, aryl or arylalkyl; A means alkyl or substituted alkyl, m is 0-2 and n is 1-3; Y means O, NR11 or S, where R11 is the same as above; X means O, NR11 or S, where R11 is the same as above, R4, R5, R8 and R9 mean independently one of the following groups (a), (b), (c), (d), (e), (f), (g), or in case where X is NR11, R4, R5, R8 and R9 can also independently mean HOOC-, R12OOC-, H2NCO- or HOHNCO-, wherein R12 means alkyl, arylalkyl or aryl, and wherein each aryl residue defined above by itself or as part of another group may be substituted, and pharmaceutically acceptable salts and esters thereof. The compounds have phospholamban inhibiting activity and are useful for treating heart failure.
Patent CA-2307469-A1 (CA)
Title: Infrared sensitive electric controlled lamp seat
Inventor: YU TSUNG-I
IPC: H05B37/02
Filed: 2000-05-03
Abstract: An infrared sensitive electric controlled lamp seat serves to control the illumination of a bulb automatically. The infrared sensitive electric controlled lamp seat includes a lamp seat and an electric controlled device. The lamp seat is an power transferring case having a U shape cone-like shape, and the upper end thereof is installed with a conductive stud, while the lower end thereof is installed with a cone net bulb fixing case. The bottom of the bulb fixing case is installed with a conductive stud for locking the bulb.      The electric controlled device is a circuit board. The center of the bottom is installed with an infrared sensing head. The circuit board is firmly secured to the bulb fixing case so that the infrared sensing head is exactly protected in the net case. The power transferring case serves to cover the upper portion of the bulb fixing case. Therefore, an infrared sensitive electric controlled lamp seat is formed. Thus, the present invention can be installed to another lamp seat for inserting a bulb so as to automatically sense and control the illumination of a bulb.
Patent CA-2308095-A1 (CA)
Title: Thermostable alcohol dehydrogenases
Inventor: NIKOLSKY YURI
IPC: C12N9/04
Filed: 1998-10-26
Abstract: The present invention provides proteins having alcohol dehydrogenase activity. In a particular embodiment, proteins having chiral alcohol selective alcohol dehydrogenase activity. In another embodiment, proteins having thermostable alcohol dehydrogenase activity are provided.
Patent CA-2308998-A1 (CA)
Title: Method for making rotors
Inventor: HAMPEL KURT
IPC: C12N15/11
Filed: 2000-05-19
Abstract: A method for making rotors for screw-type machines with a plunge-cut turning method in which an approximately rectangular groove is formed approximately at a center of a work piece with trilateral machining, a groove is cut radially deeper by trilateral machining until a predetermined groove depth has been reached, the profile flanks are shaped by bilateral machining, and the groove depth is increased with a recessing tool.
Patent CA-2310056-A1 (CA)
Inventor: ORR WILLIAM C
IPC: C10L1/18
Filed: 1999-06-17
Abstract: A fuel composition relating to a broad spectrum of pollution reducing, improved combustion performance, and enhanced stability fuel compositions for use in jet, aviation, turbine, diesel, gasoline, and other combustion applications. More particularly, the present invention relates to metallic vapor phase combustion fuel compositions employing certain co-combustion agents, including trimethoxymethylsilane.
Patent CA-2311477-A1 (CA)
Title: Absorbable block copolymers and surgical articles fabricated therefrom
Inventor: ROBY MARK
IPC: A61L17/12
Filed: 1998-09-24
Abstract: Block copolymers for making surgical articles such as sutures have a first block, a second block wherein the first block includes about 40 mole percent to 65 mole percent of repeating units derived from glycolide randomly combined with about 60 percent to 35 percent of repeating units derived from lactide, and the second block contains a higher proportion of repeating units of glycolide than the first block.
Patent CA-2315828-A1 (CA)
Title: Processes for preparing alkylene glycol esters of dimer fatty acids
Inventor: BEHLER ANSGAR
IPC: C07C67/26
Filed: 1998-12-04
Abstract: Disclosed is a method for producing alkylene glycol esters from dimer fatty acids by adding alkylene oxides to dimer fatty acids, whereby the work is carried out in the presence of alkanol amines as catalysts. The inventive method is characterised by high selectivity.
Patent CA-2317760-A1 (CA)
Title: Piperazino derivatives as neurokinin antagonists
Inventor: SHUE HO-JANE
IPC: A61P11/06
Filed: 1999-01-11
Abstract: The invention relates to neurokinin antagonists of formula (I) wherein Z, Rc, y, m, u, Ar2, n, X, Rc', I and Ar2 are as described herein. These compounds are useful in the treatment of diseases such as asthma, anxiety, depression, emesis and nociception.
Patent CA-2318572-A1 (CA)
Title: Dispositif optoelectronique pour modulation du flux d'electrons
Inventor: HAGMANN MARK J
IPC: H01J1/304
Filed: 1998-11-24
Abstract: Cette invention concerne un appareil assurant le déclenchement ultra-rapide d'un courant électrique en fonction de l'interaction résonante entre des électrons en effet tunnel et des champs optiques. L'appareil de l'invention polarise une pointe émettrice d'électrons au moyen d'une source de courant continu et focalise une émission laser sur cette pointe émettrice d'électrons de façon à stimuler l'émission d'électrons par la pointe émettrice d'électrons, laquelle pointe émettrice d'électrons est garnie d'un revêtement destiné à renforcer l'effet du champ optique du laser d'impact. L'émission d'électrons déclenche un signal électrique qui est couplé au circuit pour traitement ultérieur. Cette invention concerne, d'une part plusieurs procédés de couplage du signal électrique provenant de la pointe émettrice d'électrons, d'autre part divers procédés permettant de réduire l'importance de l'émission laser nécessaire pour stimuler une émission d'électrons, et enfin des procédés visant à augmenter la densité du courant statique.
Patent CA-2320155-A1 (CA)
Inventor: LEIBERICH RICARDA
IPC: C01G53/00
Filed: 1998-08-13
Abstract: The invention relates to a method for producing lithium-transition metal mixtures of general formula Lix(M1yM21-y)nOnz, wherein M1 represents nickel, cobalt or manganese, M2 represents chromium, cobalt, iron, manganese, molybdenum or aluminium, and is different from M1, n is 2 if M1 represents manganese and is 1 otherwise, x is comprised between 0.9 and 1.2, y is comprised between 0.5 and 1.0 and z is comprised between 1.9 and 2.1. According to the inventive method, an intimate mixture composed of transition metal compounds containing oxygen and of a lithium compound containing oxygen is calcinated, said mixture being obtained by processing a solid powder transition metal compound with a solution of said lithium compound, and then drying. At least the M1 compound is used in powder form having a specific surface of at least 20 m2/g (BET) and calcination is carried out in a fluidised bed.
Patent CA-2320319-A1 (CA)
Inventor: TASAKA SHIGEYUKI
IPC: C07D409/14
Filed: 1999-02-03
Abstract: L'invention concerne des dérivés de 1,4-dihydropyridine représentés par la formule générale (I), des antagonistes vis-à-vis de la tolérance aux anticancéreux ou aux potentialisateurs d'anticancéreux dont le principe actif renferme les dérivés en question, et les sels pharmaceutiquement acceptables ou les hydrates de ces dérivés. Dans ladite formule, R¿1? est phényle éventuellement substitué ou pyridyle; R¿2? est alkyle inférieur C¿1-5?; R¿3? est alkyle inférieur C¿1-8? éventuellement substitué, alcényle ou alkynyle ou cycloalkyle inférieur C¿3-7? éventuellement substitué ou cycloalcényle; et R¿4? est -A-R¿5? (sachant que A représente alkynylène C¿3-5? à triple liaison et que R¿5? est pyridyle éventuellement substitué, quinolyle, isoquinolyle, ou pyrimidyle).
Patent CA-2320324-A1 (CA)
Title: Improvements in or relating to reducing water flow
Inventor: MUNDAY KEITH
IPC: E21B33/138
Filed: 1999-01-28
Abstract: A water shut-off is provided in a hydrocarbon well by injecting a first chemical composition, viz. a relative permeability modifier, into the hydrocarbon and a water zone of the well followed immediately by the injection of a second chemical composition, viz. a flow blocking chemical composition, into said zones and, after a shut-in period for reaction of the relative permeability modifier, back producing the chemical compositions from the hydrocarbon zones to provide a path for said hydrocarbons from said zones whilst allowing the flow blocking chemical compositions to form the water shut-off in said water zones.