baber/WOPTO huggingface dataset:
Patent NZ-240180-A (NZ)
Title: 4-IMINOPYRROLO[2,3-d]PYRIMIDINE DERIVATIVES; PHARMACEUTICAL COMPOSITIONS.
Inventor: HARGREAVES RODNEY BRIAN
IPC: A61P9/06
Filed: 1991-10-10
Abstract: This invention concerns novel heterocyclic compounds of formula I (and pharmaceutically-acceptable salts thereof): <CHEM> wherein: R<1> is hydrogen, (1-8C)alkyl or phenyl(1-4C)alkyl; R<2> is (1-6C)alkyl, phenyl(1-4C)alkyl, (3-6C)cycloalkyl, (3-6C)cycloalkyl(1-4C)alkyl or phenyl; R<3> is hydrogen, (1-6C)alkyl, phenyl(1-4C)alkyl, (3-6C)cycloalkyl, (3-6C)cycloalkyl(1-4C)alkyl, phenyl or (3-6C)alkenyl; R<4> and R<5> are indepentently selected from hydrogen and (1-6C)alkyl; and wherein the phenyl ring and/or one or more of said phenyl or benzene moieties may optionally be unsubstituted or substituted by one or more substituents independently selected from halogeno, (1-4C)alkyl, (3-6C)alkenyl, (1-4C)alkoxy, cyano, trifluoromethyl, nitro, carboxy, (1-4C)alkylamino, dialkylamino of up to six carbon atoms, (1-4C)alkylthio, (1-4C)alkylsulphinyl, (1-4C)alkylsulphonyl and (1-4C)alkylsulphonyl and (1-4C)alkylenedioxy; but excluding the compound in which R<1>, R<3>, R<4> and R<5> are each methyl, the phenyl ring is unsubstituted and R<2> is ethyl, and its pharmaceutically-acceptable salt. The compound of formula I (and pharmaceutically-acceptable salts thereof) possess beneficial effects on the cardiovascular system, and in particular beneficial effects modulated via the sino-atrial node. Also included are processes for the manufacture of compounds of the formula I (or a pharmaceutically-acceptable salt), and pharmaceutical compositions.
Patent NZ-244212-A (NZ)
Title: Apparatus and process for making articles comprising a concertina folded sheet attached to a stiff cover sheet
Inventor: MCDONALD GEORGE WALLACE
IPC: B31D5/00
Filed: 1992-09-04
Abstract: Apparatus for use in producing an article comprising a sheet of material, characterised in that it contains means to stiffen a portion only of said sheet by an addition thereto of non-stiff matter and possibly curing the same. <IMAGE>
Patent NZ-244870-A (NZ)
Title: Preparative process for 2-c -c alk-1-en-1-ylbenzenesulphonic acid n-[4-(5-cyclopentyloxyamino-1-methylindol-3-ylmethyl)-3-methoxybenzoy l]amides;dicyclopentyl dicarbonate as acylating agent
Inventor: GERSPACHER MARC
IPC: A61K31/40
Filed: 1992-10-23
Abstract: The invention relates to a novel process for the preparation of compounds of the formula I <IMAGE> in which R is straight-chain C2-C4-alk-1-en-1-yl, and salts of these compounds, as well as a novel starting material and the use thereof.
Patent NZ-248597-A (NZ)
Title: Piperazinyl thienopyridines & analogues & medicaments
Inventor: HRIB NICHOLAS JOSEPH
IPC: A61K31/495
Filed: 1993-09-07
Abstract: The present invention relates to heteroarenylpiperazines of formula 1   <CHEM>  and a process for their preparation. The compounds exhibit antipsychotic activity and can, therefore, be used as medicaments.
Patent NZ-264197-A (NZ)
Title: Insulin formulation comprising ultralente insulin crystals and zinc
Inventor: HOFFMANN JAMES ARTHUR
IPC: A61P3/08
Filed: 1994-08-08
Abstract: The present invention is directed to an insulin formulation comprising a suspension of Ultralente crystals and a total formulation zinc concentration of between about 0.5 milligrams to about 20 milligrams per 100 units of insulin. Greater than fifty percent of the total zinc in the formulation resides in the soluble fraction, rather than in complex with the insulin. This insulin formulation generally has a pH from between about 6.0 to about 7.4. In addition, the insulin formulation of the present invention does not contain other proteins like protamine. This zinc-modified formulation displays characteristics of a very long lasting human insulin product.
Patent NZ-264376-A (NZ)
Title: Amides formed from an amino acid or dipeptide derivative and a 3-amino-2-hydroxyoxaheterocyclic derivative
Inventor: SOHDA TAKASHI
IPC: C07D307/16
Filed: 1994-09-02
Abstract: The present invention provides novel compound of the formulas (Ia) or (I): <CHEM> wherein Q is one or two amino acid residues which may be substituted; R<3> is a carboxyl group which may be esterified or an acyl group; A is an alkylene group; B is hydrogen or an alkyl group which may be substituted or an acyl group; or a salt thereof; <CHEM> wherein R<1> and R<2> may be the same or different and each is hydrogen or a hydrocarbon residue which may be substituted; R<3>, A and B have the same definitions as those shown above; m and n each is 0 or 1; provided that where both m and n are both equal to 0, R<3> is a carboxyl group which may be esterified or an acyl group having not less than 7 carbon atoms; or a salt thereof. The compound (Ia) or (I) shows cathepsin L inhibitory and bone resorption inhibitory activities and are useful as a prophylactic/therapeutic agent for osteoporosis.
Patent NZ-264537-A (NZ)
Title: Hydroxy-cholecalciferol derivatives and medicaments
Inventor: MCLANE JOHN ARTHUR
IPC: C07C401/00
Filed: 1994-09-26
Abstract: The invention relates to the compounds 1,25-dihydroxy-16-ene-24-oxo-cholecalciferol and 1,24,25-trihydroxy-16-ene-cholecalciferol which stimulate differentiation of HL-60 cells, rendering them useful as an agent for the treatment of neoplastic diseases such as leukemia, and also decrease proliferation of human keratinocytes, rendering them useful as an agent for the treatment of hyperproliferative disorders of the skin such as psoriasis. They are prepared by perfusing 1,25-dihydroxy-16-ene-cholecalciferol in rate kidneys, extracting the perfusate and isolating 1,25-dihydroxy-16-ene-24-oxo-cholecalciferol and 1,24,25-trihydroxy-16-ene-cholecalciferol.
Patent NZ-264683-A (NZ)
Title: Galanthamine derivatives and medicaments
Inventor: KOSLEY RAYMOND W
IPC: C07D491/048
Filed: 1994-10-13
Abstract: A compound of the formula (II) <CHEM>  wherein   R<1> is hydrogen, (C1-C12)alkylcarbonyl, (C1-C12)alkoxycarbonyl, mono(C1-C12)alkylaminocarbonyl or di(C1-C8)alkylaminocarbonyl; R<2> hydrogen, nitrogen containing heterocyclyloxy, or nitrogen containing heterocyclylcarbonyloxy; wherein the heterocyclyl groups are selected from 5 or 6 membered saturated or partially unsaturated rings, optionally fused to another saturated, unsaturated or aromatic ring;     R<3> is hydrogen, halo or (C1-C4)alkyl;   R<4> is hydrogen or (C1-C6)alkyl; with the proviso that R<1> and R<2> are not both hydrogen when R<3> and R<4> are hydrogen; all geometric, and optical and stereoisomers thereof, or a pharmaceutically acceptable addition salt thereof.
Patent NZ-270916-A (NZ)
Title: Transparent plastics bottle carrier encircles bottles and prevents bar codes on each item being read by a bar code reader
Inventor: WEAVER WILLIAM N
IPC: G09F3/00
Filed: 1995-04-11
Abstract: A substantially transparent carrier (24) for carrying a group of items (20), such as bottles which hold beverage, is made of a plastics material which includes a chemical blocking agent. The package (22) of carrier (24) and items (20) or carrier (24) may include a machine readable bar code (38) thereon. Each item (20) includes an individual machine readable bar code (34) thereon which is at least partially covered by the carrier (24). The chemical blocking agent blocks, by reflection or absorption, light having a narrow wavelength "tuned" or selected to prevent the individual bar codes (34) on the items (20) from being read by a bar code reader while allowing the bar code (38) on the carrier (24) or package (22) to be read. <IMAGE>
Patent NZ-500295-A (NZ)
Title: Sending messages to EPLs (electronic price labels) only if predetermined content is compatible with predetermined characteristics of EPLs
Inventor: BHYRAVABHOTLA RAGHURAMA
IPC: G06F3/048
Filed: 1999-10-13
Abstract: A message is sent to an EPL by the steps of: determining the characteristics of the EPL; obtaining content for the message to be sent to the EPL; verifying that the content is compatible with the characteristics of the EPL; and sending the message to the EPL only if the content is compatible with the characteristics of the EPL.
Patent NZ-502004-A (NZ)
Title: A wall cladding support with a ribbed mid section and longitudinal recess of either side of the ribbed section
Inventor: HARKINS MICHAEL
IPC: E04D3/38
Filed: 1999-12-21
Abstract: A cladding support (1) is provided suitable for orienting, supporting and/or sealing a wall cladding (6).  The cladding support (1) includes a member of substantially rigid material having a first face including a ribbed section (2) including a least one longitudinal rib location in a mid region of the first face and at least one longitudinal recess (3,4) on either side of the ribbed section (2).  The rib or ribs (2) are provided to form an abutment against which an edge of the wall cladding (6) is located so as to orient the wall cladding (6) in a particular orientation relative to the cladding support (1).   Also provided is an interconnectable wall-cladding unit including a wall cladding panel (6) engaged with the cladding support (1) through an adhesive sealant (9A).
Patent NZ-503507-A (NZ)
Title: Preformed coving suitable for casting into bund wall, and having tangential sealing portion and attachment for coupling to floor fixing device
Inventor: SALVITTI JOHN
IPC: E04H5/10
Filed: 1998-09-22
Abstract: A preformed coving (1) is disclosed suitable for casting into a bund wall (69), said coving (1) including: a base portion (3) positionable on or in close proximity to a floor (37) and having a concave curved front face (5) and a dependent flange (11) adapted for location in a recess in said floor; a wall portion (7) having a front face (9); and attachment means (23) remote from said front faces adapted to receive a fixing device (47) for securing said coving (1) to said floor (37). The coving (1) may further include support means (31) to receive a support and/or spacer element (57) to support a reinforcing rod (67) to be cast into the bund wall (69) or to space one coving from another when the bund wall (69) requires a coving on each of its sides.
Patent NZ-505221-A (NZ)
Title: Method with apparatus for determining the provenance of a data carrying disc
Inventor: HEYLEN RICHARD A A
IPC: G11B20/00
Filed: 1998-12-22
Abstract: A method of determining the provenance of a data carrying disc comprises the steps of a) determining physical characteristics of selected data recorded on a first test disc whose provenance is to be determined and b) comparing the physical characteristics determined with the physical characteristics of the same data on a second data carrying disc produced from a known source to determine whether the test disc has been produced from the known source wherein the physical characteristics determined have arisen inherently out of the manufacturing process from which the first and second discs are produced.
Patent NZ-510328-A (NZ)
Title: Retroviral protease inhibiting compounds
Inventor: SHAM HING LEUNG
IPC: C07D277/34
Filed: 1996-12-06
Abstract: The compound (2S,3S,5S)-2-(2,6-dimethylphenoxyacetyl)amino-3-hydroxyl-5-[2S-(1-tetrahydro-pyrimid-2-only)-3-methylbutanoyl]amino-1,6-diphenylhexane, amorphous forms, and amorphous solid forms are claimed. Also claimed is the use of the compound in the manufacture of medicaments and medicaments containing the compound for the treatment of HIV infection and for inhibiting HIV protease. (62) Divided out of 338003
Patent NZ-511340-A (NZ)
Title: Lipolytic enzyme variants
Inventor: BOJSEN KIRSTEN
IPC: A23L7/104
Filed: 1999-11-29
Abstract: A lipolytic enzyme variant is produced by selecting a parent lipolytic enzyme having an alcohol binding site having a glycerol part with an sn2 position. At least one amino acid residue in the parent lipolytic enzyme which comprises at least one atom within 10 A of the C atom at the sn2 position of the glycerol part of a substrate triglyceride in a three-dimensional structure of the parent lipolytic enzyme and the substrate is selected. The amino acid residues are altered by an insertion, a deletion or a substitution. Then, optionally, making alterations each of which is an insertion, a deletion or a substitution of an amino acid residue at one or more positions other than an amino acid residue of above. The resulting variant is then prepared and the substrate specificity tested. A variant having altered substrate specificity is selected and produced. Preferably the parent lipolytic enzyme is from a fungus belonging to the Humicola or Zygomycetes family.
Patent NZ-512532-A (NZ)
Title: Combinations for treating cardiovascular diseases like hypercholesterolemia and atherosclerosis
Inventor: KELLER BRADLEY T
IPC: A61K31/77
Filed: 1999-12-17
Abstract: Combinations of cardiovascular therapeutic compounds for the prophylaxis or treatment of cardiovascular disease including hypercholesterolemia and atherosclerosis are disclosed, which include an ileal bile acid transport inhibitor combined with a cholesteryl ester transport protein (CETP) inhibitor, a fibric acid derivative, a nicotinic acid derivative, a microsomal triglyceride transfer protein inhibitor, a cholesterol absorption antagonist, a phytosterol, a stanol, an antihypertensive agent, or others. Further combinations include a CETP inhibitor with a fibric acid derivative, a nicotinic acid derivative, a bile acid sequestrant, a microsomal triglyceride transfer protein inhibitor, a cholesterol absorption antagonist, or others.
Patent NZ-513123-A (NZ)
Title: An improved blade for a vent grille
Inventor: DIBLEY JOHN FRANCIS
IPC: F24F13/075
Filed: 2001-07-25
Abstract: A vent blade has a transverse cross-section defining the blade thickness. The blade has ends, a leading edge, a trailing edge, an upper surface, and a lower surface in use. The shape of the transverse cross section of the blade is selected to reduce fluid drag and fluid turbulence over at least one of the surfaces. The blade has at least two portions, wherein at least one of the portions has different stiffness characteristics to the other portion.
Patent NZ-514260-A (NZ)
Title: A composition comprising Group C streptococcal phage associated lysin enzyme, and the use of this composition for preventing or treating streptoccocal infections
Inventor: FISCHETTI VINCENT
IPC: C12N9/50
Filed: 1999-02-25
Abstract: A composition for use in the therapeutic or prophylactic treatment of a streptococcal infection, comprising an effective amount of Group C streptococcal phage associated lysine enzyme and a carrier for delivering this enzyme to a mouth, throat, or nasal passage, wherein the lysine enzyme kills bacteria responsible for the infection. The above-described composition is useful for the therapeutic or prophylactic treatment of streptococcal infections or the alleviation of symptoms thereof.
Patent NZ-518988-A (NZ)
Title: Building panel
Inventor: CAMPBELL NORMAN WOOD
IPC: E04C2/38
Filed: 2000-10-24
Abstract: A light-weight building panel, a building system incorporating the panels and the process of making them. The process includes a cementimous material in the form of a fibre-reinforced cellular concrete which weights approximately 26% of regular concrete. Light-weight metal members are partially embedded in the cementimous material during the manufacturing of the panel and the members project therefrom. One embodiment has exposed "C"-shaped channel members that provide, in a wall or floor panel, studs ready in place to receive plaster board or dry-wall sheets. It also provides a recessed wall for installation of electric boxes and the like.
Patent NZ-521219-A (NZ)
Title: Marine engine exhaust with seawater traps and baffles
Inventor: HELLMANN HANS KURT
IPC: F01N7/00
Filed: 2001-02-08
Abstract: A  marine engine exhaust includes a pipe portion  with rising  elbows  10,  30  to  prevent  the  rushing  flow  of seawater  into  the  engine, and a  sinking  elbow  20  that serves  as a water trap, the bottom of which lies above  the exhaust  outlet.   A drain line 25 leads  from  the  deepest portion of the trap to a lower portion of the exhaust.
Patent NZ-531155-A (NZ)
Title: A synergistic pharmaceutical combination for the prevention or treatment of diabetes
Inventor: SZILVASSY ZOLTAN
IPC: A61K31/445
Filed: 2002-07-10
Abstract: Discloses a medicament comprising: a first pharmaceutical composition containing an antidiabetic active agent selected from the group consisting of peroxisome proliferator-activated receptor gamma-agonists, sulfonylurea derivatives and biguanidine derivatives or an anti hyperlipidemic active agent, namely a HMG coenzyme reductase inhibitor, and a second pharmaceutical composition containing O-(3- piperidino-2-hydroxy-1-propyl) amidoxime, for the prevention or treatment of a prediabetic state, metabolic X-syndrome or diabetes mellitus as well as disorders which are associated with the states listed above, namely endogenic metabolic disorders, insulin resistance, dislipidemia, alopecia and/or diffuse effluvium.
Patent NZ-531343-A (NZ)
Title: Pyrrolo pyrimidines as agents for the inhibition of cystein proteases
Inventor: BETSCHART CLAUDIA
IPC: C07D473/00
Filed: 2002-08-29
Abstract: Compounds of Formula (I) or a pharmaceutically acceptable salt or ester thereof, which are inhibitors of cathepsin K and are useful for treating diseases and medical conditions in which cathepsin K is implicated, such as, inflammation, rheumatoid arthritis, osteoarthritis, osteoporosis and tumors.
Patent NZ-541106-A (NZ)
Title: Alphanumeric keyboard input system using a game controller
Inventor: TU EDGAR ALLAN
IPC: G06F3/038
Filed: 2003-12-03
Abstract: A computer program embodied on a computer readable medium for character selection comprises program instructions that provide a plurality of cells (302); program instructions that receive a first command to select a particular cell of the plurality of cells and program instructions that receive a second command to select a particular character of the plurality of characters within the selected cell. Each cell includes a plurality of characters and the first command is initiated through a directional control that enables the selection of the particular cell. The second command is initiated by a specific button of a set of buttons. Each of the set of buttons corresponds to specific ones of the plurality of characters within the selected cell so that the second command that is initiated by the specific button defines the selection of one character and the directional control is different from the set of buttons.
Patent NZ-543638-A (NZ)
Title: Heteroaryl-substituted imidazole derivatives as glutamate receptor antagonists
Inventor: BUETTELMANN BERND
IPC: C07D233/54
Filed: 2004-06-07
Abstract: Disclosed is a compound of formula I, in which R2 is C1-C6 alkyl, R3 is optionally substituted 5 or 6 membered heteroaryl and the remaining substituents are as defined in the specification. Also disclosed is a process for preparing the compounds, which are useful for the treatment and prevention of mGluR5 receptor mediated disorders such as chronic and acute neurological disorders, chronic and acute pain, urinary incontinence and anxiety.
Patent NZ-544105-A (NZ)
Title: Integrated vehicle receiver pin and clip
Inventor: VAN HANDEL MARK
IPC: F16B21/14
Filed: 2004-06-29
Abstract: An integrated pin and clip for securing vehicle trailer components. The integrated pin and clip includes a shaft member(25) and a clip member(20). The clip member(20) is movable between a locked and an unlocked position. The unlocked position allows for the integrated pin and clip to be inserted and withdrawn from a receiving aperture in a vehicle trailer component, such as a receiver. The locked position does not allow the integrated pin and clip to be inserted and withdrawn from the aperture. The integrated pin and clip also includes retention means that secures the clip in either the locked position or the unlocked position.
Patent NZ-544184-A (NZ)
Title: Fruit picking device that fits over thumb and index finger for picking fruit with a stalk that uses the flexing of the index finger to cut the stalk
Inventor: ALBER ALFONS
IPC: A01D46/247
Filed: 2003-08-25
Abstract: A fruit picking device is disclosed. The device is secured on the hand for picking fruit, in particular for pressure-sensitive fruit. The connection between the cutting element (1), the hands and fingers enables the picker to fell the surface and stalk (9) of the fruit with the fingers in order to guide the cutting element into the best position for cutting the stalk (9). The cutting element (1) is spoon-shaped in such a way that the severed fruit stalk (9) does not project beyond the surface of the fruit. The cutting element (1) comprises support elements (3) and is fixed to thumb and forefinger finger using suitable fixing means (4). A movement of the forefinger exerts a force on the cutting element, the relive movement of the thumb and forefinger being guided by the pivot points (5). The fruit picking device prevents harvested fruit from being damaged by mutual contact during storage and permits a sufficient length of stalk (9) to be retained on the fruit to prevent it from perishing.
Patent NZ-546492-A (NZ)
Title: Method and apparatus for utilising wave energy
Inventor: STANSBY PETER KENNETH
IPC: F03B13/14
Filed: 2004-10-15
Abstract: Apparatus for extracting energy from waves is disclosed. The apparatus comprising a float device (10) coupled to a shaft (16) so that vertical movement of the float devices drives the shaft. Movement of the float device is generated by the wave motion, and the mass of the float device is such that its natural frequency of vertical oscillation is substantially resonant with the frequency of a sea wave. The mass of the float device is adjustable to achieve this. Side to side motion of the float device is restricted by tethers.
Patent NZ-555882-A (NZ)
Title: Apparatus and method to elute microorganisms from a filter
Inventor: STEGGLES DARRON
IPC: B01D29/66
Filed: 2005-12-16
Abstract: A method for eluting microorganisms from filter media is disclosed. The method comprises the steps of: (a) providing filter media suspected of containing microorganisms and disposed in a housing, wherein the housing includes an inlet and an outlet; (b) providing a reservoir configured to store a quantity of a liquid buffer solution therein; (c) pressurizing the liquid buffer solution to a predetermined pressure; and (d) forcing the pressurized liquid buffer solution from the reservoir into the housing via the outlet, through the filter media, and out of the housing via the inlet to at least partially elute the microorganisms from the filter media.
Patent NZ-560607-A (NZ)
Title: Proteasome inhibitors and methods of using the same
Inventor: OLIVA AMBROGIO
IPC: A61P43/00
Filed: 2006-02-10
Abstract: The disclosure relates to boronic acid compounds for formula (I), boronic esters, and compositions thereof that can modulate apoptosis such as by inhibition of proteasome activity. These compounds and compositions can be used in methods of inducing apoptosis and treating diseases such as cancer and other disorders associated directly or indirectly with proteasome activity.
Patent NZ-575552-A (NZ)
Title: Process for the preparation of montelukast, and intermediates therefor
Inventor: PATHI SRINIVAS LAXMINARAYAN
IPC: A61K31/47
Filed: 2007-09-14
Abstract: Disclosed is a process for preparing a 2-(2-(2-(3(S)-(3-(2-(7-chloro-2-quinolinyl)-ethenyl) phenyl)-3-halo, 2-acetophenone of formula 7 comprising reacting a 2-(2-(2-(3(S)- (3-(2-(7-chloro-2-quinolinyl)-ethenyl) phenyl)-3-hydroxy, 2-acetophenone of formula 2 with a halogen donating compound.
Patent NZ-575640-A (NZ)
Title: Heterocyclic derivatives as opioid modulators
Inventor: BRESLIN HENRY J
IPC: C07D217/26
Filed: 2003-04-17
Abstract: Disclosed are compounds of formula (Ia) and formula (Ib) which are imidazole-piperidine derivative and 1H-isoquinoline derivatives that are substituted through the nitrogen with an optionally substituted phenylalanine residue; and the derivative is also substituted in the meta position by an imidazole. These compounds are suitable for opioid receptor modulators. Also disclosed is a pharmaceutically composition and the use of the compounds for preparation of a medicament for treating pain. (62) Divided Out of 561795