baber/WOPTO huggingface dataset:
Patent PT-1470106-E (PT)
Title: Method of manufacturing an amorphous form of the hemi-calcium salt of (3r, 5r) 7- 3-phenyl-4-phenylcarbamoyl-2-(4-fluorophenyl)-5-isopropyl-pyrrol-1-yl]-3, 5-dihydroxyheptanoic acid (atorvastatin)
Inventor: STACH JAN
IPC: C07D207/337
Filed: 2003-01-30
Abstract: A method of manufacturing an amorphous form of the hemi-calcium salt of (3R, 5R) 7-[3-phenyl-4-phenylcarbamoyl-2-(4-fluorophenyl)-5-isopropyl-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid of formula (I), in which (3R, 5R) 7-[3-phenyl-4-phenylcarbamoyl-2-(4-fluorophenyl)-5-isopropyl-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid or its salt with a cation M<SUP>+</SUP> wherein M<SUP>30 </SUP> is either a cation of an alkali metal or an ammonium cation of formula R<SUB>n</SUB>N<SUP>(+)</SUP>H<SUB>(4-n) </SUB>wherein R is lower C<SUB>1</SUB>-C<SUB>5 </SUB>alkyl, n may reach values ranging between 0 and 3, is, without isolating the intermediate in the form of the hemi-calcium salt or of another salt, acid or lactone, converted, in a solution, by the treatment with the calcium salt or calcium hydroxide, or a calcium C<SUB>1</SUB>-C<SUB>5 </SUB>alcoholate, to the hemi-calcium salt, and the latter is precipitated with a C<SUB>1</SUB>-C<SUB>5</SUB>hydrocarbon or dialkylether of formula R<SUB>1</SUB>OR<SUB>2</SUB>, wherein each of R<SUB>1 </SUB>and R<SUB>2 </SUB>is a C<SUB>1</SUB>-C<SUB>5 </SUB>alkyl group. The starting acid or its salt is prepared starting from (3R, 5R) tert-butyl (6-{2-[3-phenyl-4-phenylcarbamoyl-2-(4-fluorophenyl)-5-isopropyl-pyrrol-1-yl]-ethyl}-2,2-dimethyl-[1,3]dioxane-4-yl) acetate of formula II.
Patent PT-1487856-E (PT)
Title: Human antibodies specific to kdr and uses thereof
Inventor: ZHU ZHENPING
IPC: A61P35/00
Filed: 2003-03-04
Abstract: The invention provides antibodies that bind to KDR with an affinity comparable to or higher than human VEGF, and that neutralize activation of KDR. Antibodies include whole immunoglobulins, monovalent Fabs and single chain antibodies, multivalent single chain antibodies, diabodies, triabodies, and single domain antibodies. The invention further provides nucleic acids and host cells that encode and express these antibodies.
Patent PT-1567414-E (PT)
Title: Device and process for packaging products in a stretchable plastic film
Inventor: TORRE FRANCESCO
IPC: B65B11/16
Filed: 2003-04-17
Abstract: A process and a device are disclosed for packaging products in a stretchable plastic film; the device comprises: means for supporting and heating a product; means for supplying and clamping the film in a position overlaying the product; means for contacting and adhering the film, when stretched, to the product; means for cutting the film along its still not-free side; means for locking and releasing the cut film in stretched contact with the product; means for bending and adhering the film to the product through a bending action on the whole product perimeter; means for removing the packaged product; and control means for the device.
Patent PT-1557386-E (PT)
Title: Method and device for winding a paper web into a roll
Inventor: SCHMIDHOFER RUPERT
IPC: B65H19/22
Filed: 2005-01-05
Abstract: In a tissue papermaking process to wind on to a drum, the tissue paper feed ribbon has to be taken up in a start-up process or following a web break. The feed ribbon is presented to the drum by a feed roller with an adhesive coating. The tissue paper web is picked up suddenly by the feed roller. The feed roller is initially in a static position and then progresses to very slow speed before acceleration to normal operating speed. The initial feed strip is surrendered first to a pulper assembly until the tissue paper web has reached the normal width. Also claimed is a commensurate assembly.
Patent PT-1903738-E (PT)
Title: A sound reproduction method for the session and the apparatus thereof
Inventor: LIU ZHENHUA
IPC: H04L29/02
Filed: 2006-04-06
Abstract: A method for an announcement for a session includes: adding at least one playing termination in a context of a session; setting up a topology descriptor between a playing termination and a termination which is about to listen to the announcement in the context; and playing the announcement by the playing termination to the termination connected to the playing termination. An apparatus for an announcement for a session includes a playing termination setting unit, a topology descriptor setting unit and an announcement-playing unit. The present invention ensures that a user can always hear complete announcement even when a termination operable for playing an announcement is deleted or removed from the context and thus cannot play the announcement any more.
Patent PT-2256081-E (PT)
Title: Support structure to join an electric pallet jack to a functional device
Inventor: SONES SERGIO LLOPIS
IPC: B62B3/06
Filed: 2010-05-27
Abstract: The invention relates to a structure (2) attached to the body of an electric pallet truck (1) and covering it at least partially on the sides and top, has means, to move the structure so as to free the area above the truck's batteries, having also means (19) to join to it a functional device such as a wrapping device (14-18). The structure has an inverted U-shape formed of a top (3) and sides (4,5). The sides have a notch (10) which interacts with a pulley wheels (9) to allow horizontal movement of the structure.
Patent PT-616053-E (PT)
Inventor: JOSHI NAYAN HARSUKHRAI
IPC: C23C18/16
Filed: 1994-03-15
Abstract: A process for applying a metal coating to a non-conductive substrate without employing an electroless coating is provided. To this end the substrate is contacted with an activator and then with a self accelerating and replenishing immersion metal compsn. (A) to obtain a coated substrate. The activator comprises a noble metal/group IVA metal sol. Compsn. A is a soln. contg. (i) soluble metal salt whose metal is more noble than the group IVA metal. (ii) a group IA metal hydroxide and (iii) a complexing agent for which log k = 0.73-21.95 for an ion of the metal of the metal salt, log k being the cumulative formation constant. Also claimed is a compsn. comprising (i), (ii), and (iii) above.
Patent PT-873514-E (PT)
Inventor: HODGES ALASTAIR MCINDOE
IPC: G01N33/487
Filed: 1996-06-19
Abstract: A method for determining the concentration of reduced (or oxidised) form of a redox species in an electrochemical cell of the kind comprising a working electrode and a counter electrode spaced from the working electrode by a predetermined distance, said method comprising the steps of: (1) applying an electric difference between the electrodes; (2) selecting the potential of the working electrode such that the rate of electro-oxidation of the reduced form (or electro-reduction of the oxidised form) of the species is diffusion controlled, (3) selecting the spacing between the working electrode and the counter electrode so that reaction products from the counter electrode arrive at the working electrode; (4) determining current as a function of time after application of the potential and prior to achievement of a steady state; (5) estimating the magnitude of the steady state current, and (6) obtaining from the change in current with time and magnitude of the steady state current, a value indicative of the diffusion coefficient and/or of the concentration of the reduced form (or the oxidised form) of the species. Also disclosed is an apparatus for determining the concentration of a redox species in an electrochemical cell comprising: an electrochemical cell having a working electrode and a counter (or counter/reference) electrode, means for applying and electric potential difference between said electrodes, means for measuring the change in current with time, and characterised in that the working electrode is spaced from the counter electrode by less than 500µm.
Patent PT-858429-E (PT)
Inventor: FOURCOT FABRICE
IPC: B01D53/68
Filed: 1996-10-31
Abstract: A new composition comprises sodium bicarbonate, sodium carbonate and ammonia in the form of ammonium salts. Also claimed is the process for its preparation and its uses. The composition contains at least 70% (more preferably 80% and especially 80 - 95%) of sodium bicarbonate, less than 30% (more preferably less than 20% and especially 5 - 15%) of sodium carbonate, and less than 1% ammonia, as NH4+, (more preferably 0.2 - 0.7%). The preferred composition also contains less than 0.1% of ammonium carbamate (more preferably 0.01 - 0.06%) and less than 10% water(more preferably 1 - 6%). The product is used in the form of a fine powder.
Patent PT-900214-E (PT)
Inventor: HONG YOU WHA
IPC: C07D213/00
Filed: 1997-04-30
Abstract: PCT No. PCT/KR97/00073 Sec. 371 Date Oct. 21, 1998 Sec. 102(e) Date Oct. 21, 1998 PCT Filed Apr. 30, 1997 PCT Pub. No. WO97/42186 PCT Pub. Date Nov. 13, 1997The present invention relates to a process for preparation of 5,6-dimethyl-2-(4-fluorophenyl-amino)-4-(1-methyl-1,2,3,4-tetrahydroisoquinolin-2-yl)pyrimidine represented by the following formula (I), and its acid addition salts by reacting a pyrimidine derivative represented by the formula (II-A), in which Hal represents a halogen, with 1-methyl-1,2,3,4-tetrahydroisoquinoline represented by the formula (III),
Patent PT-996709-E (PT)
Inventor: WINOK DEBYSER
IPC: A23L33/17
Filed: 1998-05-04
Abstract: The present invention concerns an inhibitor of xylanolytic and/or beta-glucanolytic enzymes, method for obtaining the inhibitor, said inhibitor and processes for obtaining micro-organism, plant or plant material wherein the activity of the inhibitor according to the invention is increased or reduced and to the use of the inhibitor, the cited micro-organism, plant or plant material in a variety of processes and applications.
Patent PT-1044197-E (PT)
Inventor: BIEDERMANN ELFI
IPC: A61P35/02
Filed: 1998-12-16
Abstract: The invention relates to new piperidinyl-substituted pyridyl carboxamides of the general formula (I), wherein the structure element E has meanings (E1) or (E2) and whereby the heterocyclic ring can optionally have a double bond. These substances have especially high cytostatic activities and pronounced immunosuppressive properties which make them suitable for therapeutic treatment in broad tumor spectrum.
Patent PT-987159-E (PT)
Inventor: HUBERT M LLER
IPC: B61D17/04
Filed: 1999-09-03
Abstract: At least one middle section (1', 1'' ; 3', 3'') is fitted into the underframe (1), car side walls (2) and roof (3), the width of which determines the car width.
Patent PT-1043268-E (PT)
Inventor: RUF HANS
IPC: B66F9/14
Filed: 1999-03-29
Abstract: The vehicle has a driver's operating unit (1), wheels and a lifting mast (3) behind the front wheel axle (9a), a lifting uni for raising a bearer vertically along the mast and a positioning device (6) attached to the bearer. The lifting mast is laterally of to the longitudinal vehicle axis and in front of the operating unit. The positioning device is longer than its vertical height a is inclined wrt. the vertical mast axis, preferably at more than 30 degrees.
Patent PT-1115719-E (PT)
Inventor: ULIBARRI GERARD
IPC: C07D473/08
Filed: 1999-09-22
Abstract: Amidines (I) are new. <??>Amidines (I) of formula (I') and their salts are new. <??>A = phenyl, benzhydryl or a group of formula A1 - A9; <??>R1-R3 = halo, OH, SR6, 1-6C alkyl, 2-6C alkenyl, 1-6C alkoxy or NR6R7; <??>R4 = H or 1-6C alkyl; <??>R5 = OH, SR6, 1-6C alkyl or 1-6C alkoxy, but may not be SR6 nor alkoxy in A4; <??>R6 = H, 1-6C alkyl or 1-6C alkoxy; <??>R7 and R8 = H, OH, 1-6C alkyl or -CO-R9 but may not be alkyl nor COR9 in A5; <??>R9 = H, OH, 1-6C alkyl or 1-6C alkoxy, but may not be H, OH nor alkoxy in A1; <??>R10 and R11 = H or OH; <??>B' = 1-6C alkyl, 5-6 membered carbocyclic or heterocyclic aryl (heterocycle having 1-4 O, N, or S atoms, aryl optionally substituted by 1-6C alkyl, 1-6C alkoxy or 2-6C alkenyl) or NR13R14; <??>R13 and R14 = H or 1-6C alkyl; or <??>NR13R14 = 5 or 6 membered non-aromatic heterocycle comprising CH2, NH, O or S; <??>X = -(CH2)m-, -O-(CH2)m-, -S-(CH2)m-, -NR15-(CH2)m-, -CO-NR15-, -O-(CH2)m-CO-, -S-(CH2)m-CO-, -NR15-(CH2)m-CO- or -(CH2)m-C(OH)(CH3)-CO-; <??>Y' = -(CH2)n- or -(CH2)r-Q-(CH2)s-; <??>Q = piperazine, homopiperazine, 2-methyl piperazine, 2,5-dimethyl piperazine, piperidine, 1,2,3,6-tetrahydropiperidine, pyrrolidine, azetidine or a saturated 3-7C chain; <??>T = -(CH2)p-O-(CH2)q-, -(CH2)p-S-(CH2)q-, -(CH2)p-NR16-(CH2)q-, -(CH2)p-CO-NR16-(CH2)q-, or -CO-(CH2)p-NR16-(CH2)q-; <??>R12, R13, R14, R15, and R16 = H or 1-6C alkyl; <??>m, n, p, q, r, and s = 0-6;and <??>provided that when A = A6, then Y' is piperidine, and when A = A4, then Y' is -(CH2)r-Q-(CH2)s in which Q is a saturated 3-7 membered ring.
Patent IE-44244-L (IE)
Title: Venting device for stomas
IPC: A61F5/44
Filed: 1977-01-04
Abstract: The invention concerns a device for venting stomas and other discharge openings for metabolic products from the human body, the venting device being adapted to be placed in close direct or indirect relationship to the human body and stoma or other body opening, the venting device having a dimension perpendicular to the human body less than at least one dimension parallel to the body, the venting device containing an odor-removing filter material between gas- and liquid-tight walls with delimited passage for gaseous substances, the odor-removing filter material being passed by gases by a path longer than the dimension of the filter perpendicular to the body.
[CA1108958A]
Patent IE-40722-L (IE)
Title: Indolopiperidino -alkylphenothiazines
IPC: C07D417/14
Filed: 1975-01-21
Abstract: Novel phenothiazines of the formula WHEREIN X is selected from the group consisting of hydrogen, chlorine, trifluoromethyl, methylthio and methoxy, B is selected from the group consisting of hydrogen and alkyl of 1 to 3 carbon atoms, p is 0 or 1, R is selected from the group consisting of hydrogen and alkoxy of 1 to 3 carbon atoms and R1 and R2 are individually selected from the group consisting of hydrogen and alkyl of 1 to 3 carbon atoms and their non-toxic, pharmaceutically acceptable acid addition salts having neuroleptic activity and frequently antihistaminic activity and their preparation.
[US3923800A]
Patent IE-850536-L (IE)
Title: Displaying information
IPC: G02F1/1524
Filed: 1985-03-04
Abstract: Image formation is effected on the basis of the generation and erasing of color centers in a semiconducting oxide layer disposed between an electron injection layer and a hole injection layer. An image is formed by the trapping of electrons in color-center-promoting structural defects in the oxide layer when a potential difference is applied selectively across the oxide layer with the electron injection layer being negatively biased relative to the hole injection layer so as to enforce the dual injection of electrons and holes into the oxide layer. The image is erased by applying a potential difference of opposite polarity across the electron and hole injection layers.
[US4737781A]
Patent IE-44895-L (IE)
Title: Warping
IPC: D02J1/00
Filed: 1977-03-16
Abstract: In order to prevent loops and fluff from being pushed on during the processing of non-twisted or only slightly twisted threads, the individual filaments of a thread lying next to one another are swirled by means of compressed air and are thus interlaced at more or less large intervals. If this process is carried out simultaneously with the spinning or drawing process, only large interlacing intervals can be achieved because of the high thread speed. Here, the swirling is carried out simultaneously for all the threads, after the conclusion of the thread-producing process, in the course of the warping operation which takes place relatively slowly. The threads are thus drawn from a bobbin creel (15) via breaks, thread-guide members (16), an eyelet reed (17), a fluff monitor (20), an oiling device (21) and a thread store (22) and are wound onto part warp beams (24). The swirling device (18) is preferably installed between the eyelet reed and the fluff monitor. The swirl nozzles (9) are arranged close to one another in a common housing (1, 3) and are provided with a common air-supply system. The swirling process is controlled via a regulating valve and a three-way valve (4). <IMAGE>
[GB1576355A]
Patent IE-34587-L (IE)
Title: Pump for frothy fluids
IPC: F04D29/44
Filed: 1970-05-12
Abstract: 1281965 Centrifugal separator WARMAN EQUIPMENT (INTERNATIONAL) Ltd 19 May 1970 [19 May 1969] 24075/70 Heading B2P [Also in Division F1] A centrifugal pump for frothy fluids, comprises an impeller 1 mounted in a casing 3 having an inlet 4 receiving fluid from a chamber 6 in which the feed fluid is given a vortical motion in the direction of impeller rotation by delivery through a tangential feed pipe 9. Some of the fluid, after receiving additional energy from the impeller, is returned to the feed chamber 6 by stationary helical vanes 10 to form an interface 11 to promote separation of air from the feed. Six inclined vanes 12 prevent the vortical flow from overflowing the chamber 6. The included angle of chamber wall 7 may be 55 degrees, and the feed pipe 9 may be downwardly inclined by 15 degrees.
[GB1281965A]
Patent IE-860685-L (IE)
Title: Ô-cyclodextrin derivatives
IPC: C08B37/16
Filed: 1986-03-14
Abstract: Novel  gamma -cyclodextrin derivatives which are  gamma -cyclodextrin substituted with C1-C6 alkyl, hydroxy C1-C6 alkyl, carboxy C1-C6 alkyl or C1-C6 alkyloxycarbonylC1-C6 alkyl or mixed ethers thereof and their preparation. Compositions comprising such cyclodextrin derivatives and an active ingredient which is preferably a drug and the preparation of such compositions.
Patent IE-33124-L (IE)
Title: Benzofuran and benzothiophene derivatives.
IPC: C07D333/62
Filed: 1969-05-29
Abstract: 1,265,882. Benzofuran and benzothiophan derivatives. J. R. GEIGY A.G. 29 May, 1969 [30 May, 1968], No. 27281/69. Heading C2C. Novel compounds I: in which R is C 2-7 alkyl, X is O or S, Y 1 is H, CH 3 or CH 3 O, Y 2 is H or CH 3 and Z 1 and Z 2 are H, F, Cl, Br, CH 3 , C 2 H 5 , CH 3 0, or C 2 H 5 O and their salts with bases are prepared by reaction of a compound II: with a halide R-CO-Q, Q being halo, or an anhydride (R-CO) 2 O, followed where desired by salt formation. Intermediates isolated are the compounds II prepared by reduction of the corresponding 2,3- double-bonded compound with sodium amalgam; 6 - chloro - 2 - (2,3 - epoxypropyl) - phenol, prepared from 2-allyl-6-chlorophenol and peracetic acid; 2,3 - dihydro - 2 - hydroxymethyl- 7-chlorobenzofuran, prepared by heating the above epoxy compound; 2,3-dihydro-7-chlorobenzofuran-2-carboxylic acid prepared by oxidation of the 2-hydroxymethyl compound; a mixture of 4- and 6-chloro-2,3-dihydro-2-hydroxymethyl-benzofuran, prepared similarly to the above hydroxymethyl derivative; 2,3- dihydro - 6 - chloro - benzofuran - 2 - carboxylic acid, prepared by oxidation of the 2-hydroxymethyl compound; (X) 7, 8-dimethyl-coumarin, prepared from 2,3-dimethylphenol and malic acid; (Y) 6,7-dimethyl-benzofuran-2.carboxylic acid, prepared by reaction of the coumarin derivative with Br 2 and alcoholic potassium hydroxide; 7 - ethyl coumarin; 6 - ethyl - benzofuran - 2 - carboxylic acid; 7 - chloro - 8 - methylcoumarin and 6 - chloro - 7 - methyl - benzofuran- 2-carboxylic acid, the latter four compounds being prepared similarly to (X) and (Y) above; 6 - fluoro - benzofuran - 2 - carboxylic acid, prepared by reacting p -fluoro -salicylaldehyde with bromomalonic acid diethyl ester, followed by hydrolysis; (P) 2-thioxo-5-(2,4-dichlorobenzyl. idene)-4-thiazolidinone, prepared from rhodanine and 2,4-diohlorobenzaldehyde; 2,4-dichloro-α-mercapto-cinnamic acid, prepared from the above thiazolidinone by reaction with cone. HCl; (Q) 6-chloro-benzo[b]thiophene-2- carboxylic acid, prepared from the above cinnamic acid by cyclization; 2-thioxo.5.(2,6 dichlorobenzylidene)-4.thiazolidinone; 2,3 - dihydro - 4 - chloro - benzo[b]thiophene - 2 - carboxylic acid, the latter two being prepared similarly to (P) and (Q) above; 6-ethoxy-benzo[b]thiophene, prepared by reduction of the corresponding 3-one with NaBH 4 ; and 6-ethoxy-benzo[b] thiophene-2-carboxylic acid, prepared from the last-named intermediate by reaction with butyl lithium and solid CO 2 . Pharmaceutical compositions comprise a compound I together with a suitable carrier, are administered orally, rectally or parenterally, and have saluretic, antitussive and diuretic activity.
[GB1265882A]
Patent IE-810751-L (IE)
Title: Liquid dispensing pump
IPC: B05B11/00
Filed: 1981-04-01
Abstract: A liquid dispensing pump includes a one-piece piston capable of not only effecting a pumping operation but also an outlet valve opening and closing function upon limited relative axial movement. In one embodiment, the piston reciprocates and forms a valve seat for a container vent opening extending through a closure cap provided on the pump body, and in another embodiment, the pump cylinder reciprocates and forms a valve seat for opening and closing the container vent opening. The pump chamber defined by the cylinder has a valved inlet which may be formed by a sleeve depending from the piston and an upstanding conduit in the cylinder or may be formed by a ball check valve in the cylinder.
[US4371097A]
Patent IE-800841-L (IE)
Title: Fabric
IPC: D04B21/14
Filed: 1980-04-25
Abstract: A fabric having a novel warp lift-off-resistant construction is made on a stitch-through type machine equipped with a single knitting thread guide bar and comprises a flexible substrate such as a layer of textile yarn filling elements, a plurality of warp elements laid on the substrate in the longitudinal or warpwise direction, and knitting thread forming a multiplicity of warpwise stitches in a warp lift-off-resistant configuration. The knitting thread warp lift-off-resistant configuration comprises, in one embodiment, a combination of at least one half-tricot stitch course and one or more consecutive chain stitch courses on a given knitting thread wale to bind together into an integrated structure the substrate and warp elements, to secure the substrate and warp elements against relative displacement, and to stabilize the fabric against running or lifting off of the warp elements from the fabric surface. As a result of the knitting thread warp lift-off-resistant configuration, the fabric exhibits an aesthetically pleasing appearance corresponding to the loft imparted to the warp elements by virtue of the non-binding of the warpe lements by the chain stitch components of the knitting thread network.
[US4285216A]
Patent FI-821422-L (FI)
Inventor: APPELGREN CURT HENRY
IPC: A61K31/60
Filed: 1982-04-23
Abstract: According to the present invention an oral pharmaceutical preparation of acetylsalicylic acid is provided which consists of cores containing acetylsalicyclic acid as pharmaceutically active component, which cores are coated with a polymer membrane to the formation of coated granules. The preparation is characterized in that the polymer membrane comprises at least one polymer selected from the group consisting of cellulose acetate phtalate and methyl esterified methacrylic acid polymers having a degree of esterification of 45-55 % whereby the amount of such polymer forms 60-45 % of the weight of the membrane, and at least one methyl esterified methacrylic acid polymer having a degree of esterification of 65-75 % and forming 45-25 % of the weight of the membrane, and a plasticizer selected from fatty alcohols and fatty acids forming 4-12 <sup>1</sup>, of the weight of the membrane, whereby the membrane represents 5-12 weight-% of the composition. With this composition a reduced effect on the gastric mucosa as compared with previously known preparations but retaining good absorbtion properties and a controlled release.