baber/WOPTO huggingface dataset:
Patent PT-842330-E (PT)
Inventor: BENZON ERNST VON
IPC: E02F5/10
Filed: 1996-07-18
Abstract: PCT No. PCT/DK96/00327 Sec. 371 Date Jul. 20, 1998 Sec. 102(e) Date Jul. 20, 1998 PCT Filed Jul. 18, 1996 PCT Pub. No. WO97/04181 PCT Pub. Date Feb. 6, 1997A method for the penetration of a body (8), having a leading edge (21) and an inclined ground contacting surface (C, D, E) extending upwardly therefrom, into a porous ground material, the pores of the ground material being at least partially filled with water. The method comprises applying a driving force to the penetrating body in the direction of penetration, and discharging from the penetrating body (8) at least one flow of high-pressure gas to the inclined surface so as to facilitate the penetration of the body. Moreover, a penetrating body (8) and a plough assembly both of which can be used in the method. The method and equipment may e.g. be used for embedding drain tubes, pipes, cables or similar objects into a ground material also at a relatively great depth larger than 100 cm. Moreover, the embedding can be performed by employing a relatively high speed and can be performed at a relatively low energy consumption.
Patent PT-873411-E (PT)
Inventor: POWERS DAVID B
IPC: C12N15/53
Filed: 1997-01-09
Abstract: Mutants of 2,5-diketo-D-gluconic acid reductase A an enzyme used to produce 2-keto-L-gluconic acid, a precursor of ascorbic acid (vitamin C), are prepared by site-directed mutagenesis. These mutants may exhibit one or more of the following characteristics: improved temperature stability, increased resistance to substrate inhibition, increased turnover of the substrate by the enzyme and increased affinity for the substrate.
Patent PT-998288-E (PT)
Inventor: CAMPBELL JAMES N
IPC: A61K31/00
Filed: 1998-03-12
Abstract: Methods and compositions for treating pain at a specific site with an effective concentration of capsaicin or analogues thereof are described. The methods involve providing anesthesia to the site where the capsaicin or analogues thereof is to be administered, and then administering an effective concentration of capsaicin to the joint. The anesthesia can be provided directly to the site, or at remote site that causes anesthesia at the site where the capsaicin is to be administered. For example, epidural regional anesthesia can be provided to patients to which the capsaicin is to be administered at a site located from the waist down. By pretreating the site with the anesthetic, a significantly higher concentration of capsaicin can be used. Effective concentrations of capsaicin or analogues thereof range from between 0.01 and 10% by weight, preferably between 1 and 7.5% by weight, and more preferably, about 5% by weight. This provides for greater and more prolonged pain relief, for periods of time ranging from one week to several weeks. In some cases the pain relief may be more sustained because the disease that underlies the pain may improve due to a variety of factors including enhancement of physical therapy due to less pain in the soft tissues which may foster enhanced mobilization of soft tissues, tendons, and joints.
Patent PT-1064275-E (PT)
Inventor: DALEN FRANS VAN
IPC: C07C235/30
Filed: 1999-03-05
Abstract: Process for the preparation of a compound of formula (VI), comprising the steps of: reacting a compound of general formula (I) with a ring-opening agent to provide a compound having general formula (II); protecting the hydroxy groups of the thus formed compound (II) with a pre-determined protective agent in order to substantially retard the reactivity thereof and provide a compound having general formula (III) or (VII), wherein the protective agent retards the reactivity of compound (II) by replacing the hydrogen atom of at least one of the hydroxy groups thereof with a carbon terminated group, whereby, in the case of compound (III) at least one of R<3> and R<4> is not hydrogen; reacting compound (III) and/or (VII) with an alkylating agent of formula R<7>X to obtain a compound having formula (IV) or (VIII) respectively, wherein R<7> preferably represents a methyl or ethyl group and X represents a halide, preferably chlorine, bromine or iodine; hydrolyzing the protective groups R<3>, R<4> and R<5>, R<6> of compounds (IV) and (VIII) respectively to obtain a compound of formula (V); relactonizing compound (V) to yield compound (VI).
Patent PT-1076663-E (PT)
Inventor: MCNAMARA DENNIS JOSEPH
IPC: C07D233/56
Filed: 1999-03-19
Abstract: The present invention provides compounds of Formula (I). The present invention also provides a method of treating cancer and treating or preventing restenosis or atherosclerosis. Also provided by the present invention is a pharmaceutically acceptable composition containing a compound of Formula (I).
Patent PT-1089783-E (PT)
Inventor: ALFRED VON SCHUCKMANN
IPC: A61M15/00
Filed: 1999-06-22
Abstract: The invention relates to a device (V) for emptying powder-containing cavities (1) sealed by means of a covering foil (9) by means of a suction tube (11) which can be set by hand and whose leading end is positioned relatively to the cavity (1) and pierces in a guided manner the covering foil (9), leaving a free cross section for air to flow into the cavity (1), and, to achieve a solution which is beneficial for production and reliable in manipulation, proposes that the leading end of the suction tube (11) has, adjacent and axially projecting with respect to cutting edges (12) provided at that point, extensions (22/82) which are guided in slots (19 and/or 83, 55 or 25, respectively) of a carrier (T) adjacent to the cavities (1) in a shape-locked/rotationally fixed manner, in which carrier (T) the cavities (1) can be inserted as blister packs (2).
Patent PT-1110031-E (PT)
Inventor: BOHLE MARKUS
IPC: G02B6/00
Filed: 1999-08-19
Abstract: A light (1) comprises a light source (4) and a wedge-shaped light guiding element (3) having two wedge surfaces (11, 13) and a light entry face (10) extending between the wedge surfaces where they are farthest apart. Light from the source (4) enters light guiding element via the face (10) and is reflected by one wedge surface (13) against the other wedge surface (11) where it exits from the light guiding element (3). To improve radiation characteristics, the other wedge surface (11), which is an exit surface, is profiled with adjacent elevations and indentations extending crosswise to the direction of the wedge. A transparent diffuser (20) is positioned at a distance in front of the exit surface (11). The side of the diffuser (20) facing away from the light exit surface is profiled with adjacent elevations and indentations. The distance between the diffuser (20) and the light guiding element (3) prevents light from entering the diffuser at any angle and thus increases the effectiveness of the profiling.
Patent SG-48188-G (SG)
Title: An arrangement for ultrasonic sealing
IPC: B65B51/22
Filed: 1988-07-16
Abstract: Arrangements for ultrasonic sealing comprising a sealing jaw (17) which is combined with an ultrasonics source (15) and a counterjaw (8). During the sealing the parts which are to be sealed to each other are pressed together between working surfaces (18, 19) of the jaws with simultaneous activation of the ultrasonics source as a result of which the parts are welded together. In the sealing of thin material layers it is very difficult to obtain a uniform compression over the whole surface which means that the risk of burning asunder or unsatisfactory sealing increases. In accordance with the invention this is prevented with the help of supporting elements (20) which engage with two stop faces (25) located in the nodal plane of the sealing jaw (17) and on the one hand determine the minimum distance between the working surface, on the other hand orientate the flexibly suspended jaw so that the working surfaces are parallel.
Patent SG-57191-G (SG)
Title: Phase-locked loop cefficient generator for a filter arrangement having a nonrational ratio between input an output sampling frequencies
IPC: H03H17/06
Filed: 1991-07-16
Abstract: In a sample rate converter having a non-rational conversion factor the input samples coincide with low-rate clock pulses and the output samples coincide with high-rate clock pulses, or inversely. It comprises a filter coeffi­cient generator 3 which, based on the distance (deviation) between a low-rate clock pulse and the immediately preceding or immediately subsequent high-rate clock pulse, con­tinuously supplies a series of filter coefficients. To de­termine the deviation a phase-locked loop (30) is provided, with a phase detector (301) receiving the low-rate clock pulses as well as synthetic low-rate clock pulses and supplying a discrete-time phase difference signal u(.) which is applied to a processor circuit (302). This circuit supplies the desired deviation d(.) and a reference number N which is applied to a counter circuit (304). This circuit also re­ceives the high-rate clock pulses and each time after re­ceiving the number of clock pulses corresponding to the reference number it supplies a synthetic low-rate clock pulse. In the processor circuit 302 a filtering operation (3021) is first performed on the discrete-time phase dif­ference signal u(.) so that control signal samples H(.) are obtained. An auxiliary sample s(.) is subtracted from such a control signal sample and the difference is divided by a weighting factor incr. of the number P thus obtained those bits whose significance is less than 2° represent the deviation d(.), while the other bits represent the reference number N. By subsequently multiplying the deviation d(.) by the weighting factor incr, a new auxiliary sample s(. + 1) is obtained.
Patent IE-880002-L (IE)
Title: Heteroaryl 3-oxo-propanenitrile derivatives
IPC: A61K31/415
Filed: 1988-01-04
Abstract: The invention relates to compounds having the general formula (I) <CHEM> wherein X represents an oxygen atom or a -S(O)n-group, wherein n is zero, 1 or 2; R1 represents C1-C6 alkyl, benzyl, pyridyl, or phenyl, the phenyl being unsubstituted or substituted by one or two substituents chosen independently from halogen, trifluoromethyl, C1-C6 alkyl, C1-C6 alkoxy, nitro, amino, formylamino and C2-C8 alkanoylamino; each of R2 and R3 is independently: a) hydrogen, halogen or C1-C6 alkyl; b) hydrogen, C1-C6 alkoxy or C3-C4 alkenyloxy; or c) nitro, amino, formylamino or C2-C8 alkanoylamino; R4 represents hydrogen or C1-C6 alkyl; and Q represents hydrogen, carboxy, CONH2, C2-C7 alkoxycarbonyl <CHEM> wherein Ra represents hydrogen or C1-C20 alkyl and Rb represents C1-C20 alkyl or a -(CH2)m-R5 group, wherein m is zero, 1 or 2 and R5 is: a') C5-C8 cycloalkyl; b') pyridyl, unsubstituted or substituted by one or two substituents chosen independently from halogen, C1-C6 alkyl and C1-C6 alkoxy; or c') phenyl, unsubstituted or substituted by one or two substituents independently chosen from halogen, CF3, C1-C6 alkyl, C1-C6 alkoxy, amino, nitro, formylamino, C2-C8 alkanoylamino, di (C1-C6 alkyl) amino, hydroxy, formyloxy and C2-C8 alkanoyloxy, and the pharmaceutically acceptable salts thereof, which possess immunodulating activity and are useful e.g. in the treatment of neoplastic diseases and acute and chronic infections of both bacterial and viral origin in mammals.
[EP0274443A1]
Patent IE-900137-L (IE)
Title: Process for graft copolymerization on surfaces of preformed¹substrates to modify surface properties
IPC: C08J7/12
Filed: 1990-01-12
Abstract: A process for modifying the surface characteristics of a preformed polymeric substrate to impart hydrophilicity, hydrophobicity or other desired properties thereto comprises peroxidizing and hydroperoxidizing the surface of said preformed substrate using ozone, directing the subsequent graft polymerization of selected ethylenically unsaturated monomers essentially solely to the surface of said substrate to achieve the desired alteration of substrate surface characteristics while maintaining substrate structural integrity. Substrates so modified are useful in biomedical devices, semipermeable membranes, films, fibers and especially contact lenses.
Patent IE-32553-L (IE)
Title: Polyene compound
IPC: A01N37/42
Filed: 1968-02-12
Abstract: 1,199,012. Polyene compounds. F. HOFFMANN-LA ROCHE & CO. A.G., and B. C. L. WEEDON. 14 Feb., 1968 [14 Feb., 1967], No. 7094/67. Heading C2C. The invention comprises aldehydes of the general formula in which R<SP>1</SP> is oxo, C 1 -C 7 alkylenedioxy or dialkoxy and R<SP>3</SP> represents CHO. They may be prepared by reducing an acetylenic compound of formula in which R<SP>2</SP> is a protecting group and R<SP>4</SP> is C 1 -C 7 alkylenedioxy or dialkoxy, with an alkali metal (e.g. Li) aluminium hydride to yield an olefinic compound of formula removing the protecting groups R<SP>2</SP> and R<SP>4</SP> by acid hydrolysis, reintroducing the R<SP>4</SP> group, if desired, and oxidizing the alcohol product, e.g. with manganese dioxide or chromic acid, to the desired aldehyde. Suitable protecting groups R<SP>2</SP> are those of formula in which R<SP>5</SP> is a C 1 -C 7 group and R<SP>6</SP> and R<SP>7</SP> each represent a C 1 -C 7 alkyl group or together form a trimethylene group. The acetylenic compound referred to above may be obtained by protecting the hydroxy group of cis-3- methyl - pent - 2 - en - 4 - yn - 1 - ol (e.g. by treating with isopropenyl methyl ether) and reacting the resisting alcohol of formula with a 2,6,6 - trimethyl - 4 - (C 1 -C 7 alkylenedioxy) - 2 - cyclohexen - 1 - one or a 2,6,6- trimethyl - 4,4 - dialkoxy - 2 - cyclohexen - 1 -one by means of a metal-organic reaction, e.g. by a Grignard reaction. Those aldehydes, in which R<SP>1</SP> is an alkylenedioxy or dialkoxy group may also be prepared by reacting a 2,6,6-trimethyl- 4 - (alkylenedioxy) - cyclohex - 2 - en - 1 - one or a 2,6,6 - trimethyl - 4,4 - dialkoxy - cyclohex- 2-en-1-one with cis-3-methyl-pent-2-en-4-yrrl-ol by a Grignard reaction, oxidizing the hydroxymethyl group of the resulting acetylenic alcohol and reducing the triple bond to a double bond. Those aldehydes in which R<SP>1</SP> is an oxo group may be prepared by this method with the additional step of hydrolysing with an acid the product at any stage. The aldehydes described above may be oxidized to give compounds of Formula (I) in which R is a C 1 -C 7 alkyl group. The oxidation may be carried out by means of silver oxide at 0-50‹ C. and the product may be converted to an ester by means of a diazoalkane, a C 1 -C 7 alkanol or an alkyl halide.
[GB1199012A]
Patent IE-840286-L (IE)
Title: Synthetic polypeptides from viral oncogenes
IPC: C07K16/00
Filed: 1984-02-07
Abstract: Synthetic polypeptides and their conjugates bound to a carrier along with antibodies raised thereto, and methods of their use. The amino acid residue sequences of the synthetic polypeptides correspond substantially to an amino acid sequence of a determinant domain of an oncoprotein encoded by an oncogenic virus. That determinant domain is vicinal to but exclusive of an active site of the oncoprotein. The synthetic polypeptide or its conjugate is capable of inducing the production of antibodies which can inhibit a reaction at an oncoprotein active site, immunoprecipitate the oncoprotein and react competitively with an admixture containing the synthetic polypeptide or its conjugate and another oncoprotein having a homologous determinant domain.
[WO8403087A1]
Patent IE-43085-L (IE)
Title: Metals or alloys.
IPC: C22C38/00
Filed: 1976-03-19
Abstract: The invention relates to a process for obtaining steels having improved machinability. This process provides for the upgrading of divided metallurgical products, which are consolidated without fusion, with incorporation of a dispersed phase. (From US4077108 A) [FR2304678A1]
Patent IE-780645-L (IE)
Title: Seismic detector
IPC: G01V/
Filed: 1978-03-31
Abstract: A long, flexible cable is drawn over the surface of the earth. This cable has liquid-filled detectors which are constructed as geophones (10) and are mounted on the cable at suitable spacings. The seismic cable receives the individual output signals of the geophone. Each geophone supplies an electrical output signal having a polarity which corresponds to the direction of the movement of the earth. Their output signals are transmitted to a processing device, and then it is moved into a different position and the measurement operation is repeated. The geophones have a cylindrical, hollow housing (12) with a chamber (34) in the interior. A liquid (36) of high density, e.g. mercury, mostly fills the chamber (34). The chamber has a flexible base plate (22) which forms a force-measuring or pressure-measuring transducer (27). In addition to the flexible base plate (22), the chamber (34) has a further flexible base plate (22') on the upper side, which likewise forms a measuring transducer (27'). The geophone supplies at its output terminals (56, 58) electrical signals corresponding to the seismic signals.
Patent FI-821295-L (FI)
Inventor: BASTENHOF DIRK
IPC: F02M59/36
Filed: 1982-04-13
Abstract: Internal combustion engine fuel injection pump of the type comprising an injection piston having a head with a helical ramp and provided with a device for adjusting in time the beginning of the fuel injection delivery. The adjusting device comprises a valve for closing and opening a bypass passage adapted to connect the said admission chamber to a space communicating with the chamber filling fuel source, and a system for the control of the valve including a control device for closing the valve depending on the angular position of a rotary member of the engine, such as a crankshaft, and for opening the valve in response to a partial vacuum created in the admission chamber by the suction stroke of the injection piston.
Patent FI-850789-L (FI)
Inventor: MALMENDIER JOSEPH
IPC: D21F1/00
Filed: 1985-02-27
Abstract: There is described a cloth for draining and drying paper webs, comprising a fabric formed by warp threads and weft threads. Said cloth further comprises a top layer of interlaced lengthwise strips and weft threads, at least one upper weft thread part passing underneath one or a plurality of lengthwise strips, being connected to the fabric by at least one warp thread thereof, which has been passed between said upper weft thread part and the lengthwise strip or strips.
Patent FI-851290-L (FI)
Inventor: GAUTHIER MAURICE
IPC: D06N3/00
Filed: 1985-03-29
Abstract: The procedure for binding a layer 26 of a permeable material onto a carrier 20 of interwoven threads is characterized in that, during the manufacture of the carrier 20, one of its sides 21 is provided with special threads which have a core and a thermoplastic outer part whose melting temperature is lower than that of the core and of the other threads, and in that this side 21 is heated until the outer side of the special threads melts, after which the layer 26 is applied on the said side. In this way the mechanical and sealing properties of the carrier and the layer are retained. The procedure is used for producing paper-making felts and felt materials. <IMAGE>
Patent IE-861126-L (IE)
Title: Production of alumina
IPC: C01F7/47
Filed: 1986-04-29
Abstract: Process for the low-temperature treatment according to the Bayer cycle of gibbsite-bearing bauxite of low reative silica content, involving desilication of the said bauxite before leaching, by a liquor of low caustic soda concentration and characterized in that this sodium liquor consists of one or more washing waters originating from the Bayer cycle, mixed or otherwise with leaching liquor, wherein the weighted reactive silica content is preferably lower than 5% of the alumina content of the bauxite and the concentration of the sodium liquor used for desilication ranges from 50 to 120 g/liter of Na2O caustic.
[US4650653A]
Patent IE-851287-L (IE)
Title: CLONED ß-AMYLASE.
IPC: C12N15/69
Filed: 1985-05-22
Abstract: Recombinant DNA has been developed which is derived from the plasmid pUB110. This plasmid comprises a gene coding for resistance to kanamycin or to analogous antibiotics inactivated by the nucleotidyl transferase enzyme.The recombinant DNA containing an amylase-coding gene is prepared by the in vitro process of cleaving DNA derived from a donor microorganism and combining the resulting DNA fragments comprising the amylase-coding gene with a similarly cleaved vector which is plasmid pUB110. This recombinant DNA may then be introduced into a host microorganism and the resulting genetically engineered microorganism has been found to have enhanced stability and high copy numbers.The host microorganism employed is preferably Bacillus subtilis and the invention is particularly suitable for the industrial scale production of the alpha-amylase of Bacillus megaterium.
Patent IE-45246-L (IE)
Title: Dibenzopyran derivatives
IPC: C07D311/78
Filed: 1977-07-05
Abstract: Reaction of an aluminum halide with a 2,7-dihydroxy-5-isopropylidene-9-substituted-2,6-methano-3,4,5,6-tetra hydro-2H-1-benzoxocin in an organic solvent effects cleavage of the pyran ring system with concomitant recyclization to provide exclusively a trans-1-hydroxy-3-substituted-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9 H-dibenzo[b,d]pyran-9-one.
[US4054583A]
Patent IE-34719-L (IE)
Title: Rotary carpet sweeper brush
IPC: A47L11/33
Filed: 1970-11-12
Abstract: 1321081 Rotary brushes; carpet sweepers PRESTIGE GROUP Ltd 5 Jan 1971 [21 Jan 1970] 3057/70 Headings A4F and A4K A carpet sweeper has a rotary brush comprising outwardly extending sweeper elements arranged in rows extending along the brush, the sweeper elements being of different flex characteristics and arranged so that each soft element in any row precedes a stiffer element in the following row in the direction of rotation so that the soft element receives dirt swept forward by the stiffer element. Each row may comprise tufts of the same flex characteristics, the soft tufts 24, Fig. 2 being larger and thinner than the stiff tufts 23; and/or the soft tufts may comprise synthetic fibres or horse hair and the stiff tufts bristle; and/or the soft tufts may have less bristles or fibres. Two or more rows of stiff tufts may be provided between each row of soft tufts. In another form, Fig. 3, each row comprises a length of soft tufts 34 spaced between lengths of stiff tufts 33, and the rows are helical. Alternatively, the sweeper elements may comprise felt.
[GB1321081A]
Patent IE-881876-L (IE)
Title: Data processing system
IPC: G06F15/177
Filed: 1988-06-21
Abstract: A data processing system is described in which the workload is divided into packets. A plurality of processors access the packets and process them by rewriting them according to predetermined rules. Packets can be of a number of different types, including XAPP and PAPP. An XAPP packet contains a function and one or more arguments in evaluated form, so that the function can be immediately applied to the arguments. A PAPP packet is similar except that its arguments may not be in evaluated form. Processing of an active PAPP packet consists of activating other packets which evaluate the arguments of the PAPP packet, and converting the PAPP to a suspended XAPP packet, awaiting return information from those other packets. The use of different packet types allows greater efficiency, by eliminating redundant actions in processing of the packets.
[EP0301695A2]