baber/WOPTO huggingface dataset:
Patent AU-2015308818-B2 (AU)
Title: Conditionally active chimeric antigen receptors for modified T-cells
Inventor: SHORT JAY M
IPC: A61K39/395
Filed: 2015-08-27
Granted: 2021-02-25
Abstract: This disclosure relates to a chimeric antigen receptor for binding with a target antigen. The chimeric antigen receptor comprises at least one antigen specific targeting region evolved from a wild-type protein or a domain thereof and having at least one of: (a) a decrease in activity in the assay at the normal physiological condition compared to the antigen specific targeting region of the wild-type protein or a domain thereof, and (b) an increase in activity in the assay under the aberrant condition compared to the antigen specific targeting region of the wild-type protein or a domain thereof. A method for generating the chimeric antigen receptor and cytotoxic cells that express the chimeric antigen receptor are also provided.
Patent AU-2015361242-B2 (AU)
Title: Debris evacuation for cleaning robots
Inventor: MORIN RUSSELL WALTER
IPC: A47L9/10
Filed: 2015-09-17
Granted: 2020-08-20
Abstract: A robot floor cleaning system (10,10') features a mobile floor cleaning robot (100,100') and an evacuation station (200,200'). The robot includes: a chassis (102) with at least one drive wheel (142a, 142b) operable to propel the robot across a floor surface; a cleaning bin ( 122, 122 ', 122") disposed within the robot and arranged to receive debris ingested by the robot during cleaning; and a robot vacuum (120) configured to pull debris into the cleaning bin from an opening (109,109') on an underside of the robot. The evacuation station is configured to evacuate debris from the cleaning bin of the robot, and includes: a housing (202,202') defining a platform (206,206') for receiving the cleaning robot with the opening on the underside of the robot aligned with a suction opening (216) of the platform; and an evacuation vacuum (212) operable to draw air into the evacuation station housing through the suction opening.
Patent AU-2015385746-B2 (AU)
Title: Heated electric towel rail
Inventor: LIM FILIPE NETO
IPC: A47K10/04
Filed: 2015-12-18
Granted: 2021-07-08
Abstract: A heated electric towel rail including a body length, a heating element mounted to heat a portion of the towel rail, and a power cord connected to the heating element to supply power to the heating element, wherein the body length has a first aperture at a first 5 location and a second aperture at a second location spaced from the first location, wherein an end of the power cord exits the body length through the first aperture, and wherein an intermediate portion of the power cord between said cord end and the heating element extends past the second aperture and is arranged to permit the intermediate portion to be drawn outwardly through the second aperture.
Patent AU-2015405065-B2 (AU)
Title: Sterilization tray protection mechanisms
Inventor: TAKKEN WENDY
IPC: A61L2/26
Filed: 2015-08-13
Granted: 2020-12-03
Abstract: A sterilization wrap system with features for protecting a sterilization wrap and/or a sterilization tray of the sterilization wrap system is provided. Such features include strap or belt protectors, edge protectors, corner protectors, and/or expandable protectors, which each may provide protection of one or more areas of the sterilization wrap and/or tray when positioned against an outer surface of the wrap and/or between an inner surface of the wrap and a container for holding implements to be sterilized. A size-selectable protection system also is provided. The size-selectable protection system provides a material having a plurality of perforations such that a length of the material may be selected and detached from the rest of the material. The selected length of material may be used with a sterilization wrap system to protect a sterilization wrap and/or sterilization tray from cuts, tears, or the like.
Patent AU-2016203362-B2 (AU)
Title: Use of il-15 to increase thymic output and to treat lymphopenia
Inventor: PAVLAKIS GEORGE N
IPC: A61K38/20
Filed: 2016-05-23
Granted: 2018-07-19
Abstract: The present invention is directed towards a method of promoting T-cell maturation in thymic tissue, or a method of promoting the migration of lymphocytes from a central lymphoid tissue to one or more peripheral tissues in a subject in need thereof, or a method of reducing lymphopenia in an individual in need thereof, or a method of promoting the repopulation of lymphocytes in peripheral tissues in an individual in need thereof, comprising the administration of IL- 15.
Patent AU-2016203846-B2 (AU)
Title: Systems, methods and devices for ozone sanitization of continuous positive airway pressure devices
Inventor: LEYVA TIMOTHY
IPC: A61L2/14
Filed: 2016-06-09
Granted: 2017-06-29
Abstract: An ozone sanitizing device comprising: an ozone operating system; and, one or more distribution lines, wherein said one or more distribution lines distributes ozone from said ozone device to a continuous positive airway pressure device. Figure 1 110 112 116
Patent AU-2016208353-B2 (AU)
Title: Immunotherapy regimes dependent on ApoE status
Inventor: WIDOM ANGELA
IPC: A61K39/00
Filed: 2016-07-28
Granted: 2017-07-20
Abstract: IMMUNOTHERAPY REGIMES DEPENDENT ON APOE STATUS Abstract The invention provides methods of immunotherapy of Alzheimer's and similar diseases in which the regime administered to a patient depends on the ApoE genotype of 5 the patient.
Patent AU-2016210755-B2 (AU)
Title: SIRP-alpha variant constructs and uses thereof
Inventor: DEMING LAURA
IPC: C07K14/71
Filed: 2016-08-05
Granted: 2021-05-13
Abstract: SIRP-ALPHA VARIANT CONSTRUCTS AND USES THEREOF 
ABSTRACT 
The invention relates to compositions and methods of SIRP-a variant constructs including SIRP-a 
variants. The SIRP-a variant constructs may be engineered in a variety of ways to respond to 
environmental factors, such as pH, hypoxia, and/or the presence of tumor-associated enzymes or tumor
associated antigens. The SIRP-a variant constructs of the invention may be used to treat various 
diseases, such as cancer, preferably solid tumor or hematological cancer.
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Patent AU-2016219917-B2 (AU)
Title: Methods, compositions, and kits for treatment of cancer
Inventor: HOLASH JOCELYN
IPC: C12P21/00
Filed: 2016-02-19
Granted: 2021-12-16
Abstract: Provided herein are the use of FGFR3 inhibitors and PD1 inhibitors to treat solid and hematologic cancers and compositions and kits comprising an FGFR3 inhibitor and a PD1 inhibitor.
Patent AU-2016232404-B2 (AU)
Title: Process for the purification of monochloroacetic acid
Inventor: TOLLIN LARS MAGNUS
IPC: C07C51/377
Filed: 2016-03-14
Granted: 2019-11-07
Abstract: The present invention pertains to a process for the purification of a feed comprising monochloroacetic acid and dichloroacetic acid wherein the feed is subjected to a catalytic hydrodechlorination step by contacting it with a source of hydrogen to convert dichloroacetic acid into monochloroacetic acid in the presence of a solid heterogeneous hydrogenation catalyst comprising a Group VIII noble metal on a carrier under hydrodechlorination conditions, wherein the reaction is carried out in the presence ofacatalyst enhancer which comprises a salt of a metal selected from the group of non-noble metals of Group VIII, Group VIB, Group VIIB, and Group IIB. It was found that the presence of a catalyst enhancer leads to reduced deactivation of the catalyst and/or increased activity of the spent catalyst. This allows longer production cycles, less downtime, and lower formation of side products. The catalyst enhancer preferably comprises one or more salts of one or more of nickel, cobalt, or iron, more in particular of iron. The salts preferably comprise one or more of chloride salts and acetate salts.
Patent AU-2016243967-B2 (AU)
Title: Compositions and use of interleukin-10 peptides and anti-interleukin-10 antibodies
Inventor: COOK MARK ERIC
IPC: A61K39/395
Filed: 2016-03-03
Granted: 2022-03-17
Abstract: Disclosed herein are methods of reducing a symptom of respiratory disease in a pre-weaned milk-fed mammal by orally administering an isolated antibody that specifically binds the interleukin-10 peptide or an anti-interleukin-10 antibody. Also included are methods of reducing mixing stress in human and non-human mammals by administering an isolated antibody that specifically binds the interleukin-10 peptide or an anti-interleukin-10 antibody. Further included are milk and food compositions including the interleukin-10 peptide or anti-interleukin-10 antibody.
Patent AU-2016256667-B2 (AU)
Title: Method and apparatus for electrode impedance measurement
Inventor: KEECH RAY
IPC: G01F1/58
Filed: 2016-11-07
Granted: 2020-12-24
Abstract: METHOD AND APPARATUS FOR ELECTRODE IMPEDANCE MEASUREMENT 
5 A method of obtaining a measure of electrical impedance in respect of one or 
more sensing electrodes of an electromagnetic flowmeter, the method comprising: 
intermittently injecting an impedance measurement signal to at least one of the 
sensing electrodes whilst a coil excitation drive signal is applied to field generating 
coils of the flowmeter; during a first interval, when the coil excitation drive signal is 
10 applied to the coils and the impedance measurement signal is injected to at least 
one of the sensing electrodes, obtaining a first measurement signal from the 
sensing electrodes, the first measurement signal comprising an 
electromagnetically induced flow measurement signal and an electrode impedance 
measurement signal; during a second interval, when the coil excitation drive signal 
15 is applied to the coils but the impedance measurement signal is not injected to at 
least one of the sensing electrodes, obtaining a second measurement signal from 
the sensing electrodes, the second measurement signal comprising an 
electromagnetically induced flow measurement signal; and combining the first 
measurement signal and the second measurement signal to obtain an output 
20 signal comprising the electrode impedance measurement signal without the 
electromagnetically induced flow measurement signal.  
Also provided is sensing apparatus which carries out such a method, and also an 
electromagnetic flowmeter comprising such sensing apparatus.  
25 
(Figure 1 to accompany Abstract.)
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Patent AU-2016274790-B2 (AU)
Title: Refurbishing nonoconductive zone in a solar pond
Inventor: NITSCHKE GEORGE SAMUEL P E
IPC: F24S60/00
Filed: 2016-06-10
Granted: 2020-10-22
Abstract: A Salinity Gradient Solar Pond (SGSP) has saturated salt water in the bottom zone of the pond and nearly fresh water at the top zone, with a gradient zone between the top and bottom. Due to this salinity stratification the upward diffusion of salt is a natural consequence in SGSP's. Controlling the salinity gradient in SGSP systems is vital to their reliable operation. The method for controlling the salinity gradient disclosed in this application, coined the "Pond Rolling Method" by the authors, rapidly drains the pond's non-gradient zones, refurbishes the gradient, and restores the non-gradient zones of the SGSP system, in a manner that minimizes land use, water and heat loss. The salt in the pond is allowed to diffuse upward over time and, on condition as needed to restore the gradient, the Pond Rolling Method is used to completely rebuild the gradient and the SGSP zones.
Patent AU-2016280358-B2 (AU)
Title: Device and method for in-line thread treatment
Inventor: EKLIND MARTIN
IPC: D04B35/22
Filed: 2016-06-16
Granted: 2021-04-22
Abstract: A device and method for in-line treatment of a thread are disclosed. The device comprises treatment and fixation units located downstream a thread feeding unit. A thread consuming system comprising a thread consuming device, such as an embroidery machine and/or a weaving machine and/or a sewing machine and the device is also disclosed.
Patent AU-2016289954-B2 (AU)
Title: Spinal implant system and method
Inventor: STEVENSON TYLER S
IPC: A61F2/44
Filed: 2016-07-06
Granted: 2021-02-11
Abstract: A spinal implant includes an implant body including a first endplate and a second endplate. A plurality of electrodes include at least one electrode disposed with the first endplate and at least one electrode disposed with the second endplate such that the electrodes conduct an electric current to stimulate tissue growth adjacent the implant body. Systems, surgical instruments and methods are disclosed.
Patent AU-2016325592-B2 (AU)
Title: Methods and systems for assessing healing of tissue
Inventor: GUREVICH LINA
IPC: A61B5/026
Filed: 2016-07-29
Granted: 2019-06-27
Abstract: Methods and systems for assessing tissue of a subject include receiving a time series of signal intensity data capturing the transit of an imaging agent through tissue over a period of time, wherein the tissue comprises a plurality of calculation regions and wherein signal intensity in each calculation region over the period of time may be approximated by a time-intensity curve corresponding to the calculation region; determining, for each calculation region, a coefficient value that is related to at least a portion of the time-intensity curve corresponding to the calculation region; and converting the coefficient values across the plurality of calculation regions into a coefficient-derived image map.
Patent AU-2017202230-B2 (AU)
Title: System and method for characterising eye-related systems
Inventor: EHRMANN KLAUS
IPC: A61B3/10
Filed: 2017-04-04
Granted: 2019-05-09
Abstract: Described herein is a light directing assembly for use in an object analysis system. The light directing assembly includes a plurality of optical relay assemblies. Each optical relay assembly includes at least one optical element configured to relay an interrogation beam from a light transmission system to an object and relay a return beam from the object to the light transmission system, the return beam being generated by reflection or back scattering of the interrogation beam by the object. Each optical relay assembly defines an interrogation angle at which the interrogation beam relayed by the optical relay assembly reaches the object, and an optical path length being the distance from the light transmission system to the object travelled by an interrogation beam via the optical relay assembly. The plurality of optical relay assemblies are further configured such that the optical path length for a given optical relay assembly has a predefined relationship with the optical path lengths of the other optical relay assemblies.
Patent AU-2017256071-B2 (AU)
Title: Reoviridae vaccine
Inventor: ROY POLLY
IPC: C12N7/00
Filed: 2017-04-10
Granted: 2022-11-17
Abstract: The invention relates to an isolated African horse sickness virus (AHSV) ssRNA comprising a plurality of mutations; a complementary cell for replication of a vaccinal viral strain from said ssRNA; a vaccinal viral strain derived from said ssRNA; use of said vaccinal viral strain and/or isolated ssRNA in the vaccination of an animal against an infectionby AHSV; a method of vaccination comprising same; and a pharmaceutical composition comprising said vaccinal viral strain and/or said isolated ssRNA.
Patent AU-2017268562-B2 (AU)
Title: Lipoprotein analysis by differential charged-particle mobility
Inventor: CAULFIELD MICHAEL P
IPC: G01N27/26
Filed: 2017-11-29
Granted: 2020-06-18
Abstract: LIPOPROTEIN ANALYSIS BY DIFFERENTIAL CHARGED-PARTICLE The invention provides apparatus and methods of preparation of lipoproteins from a biological sample, including HDL, LDL, Lp(a), IDL, and VLDL, for diagnostic purposes utilizing differential charged-particle mobility analysis methods. Further provided are methods for analyzing the size distribution of lipoproteins by differential charged-particle mobility, which lipoproteins are prepared by methods of the invention. Further provided are methods for assessing lipid-related health risk, cardiovascular condition, risk of cardiovascular disease, and responsiveness to a therapeutic intervention, which methods utilize lipoprotein size distributions determined by methods of the invention.
Patent AU-2017281348-B2 (AU)
Title: Flame resistant fabrics having fibers containing energy absorbing and/or reflecting additives
Inventor: STANHOPE MICHAEL T
IPC: A41B1/00
Filed: 2017-06-22
Granted: 2020-12-17
Abstract: Embodiments of the invention relate to flame resistant fabrics containing fibers having at least one energy absorbing and/or reflecting additive incorporated into the fibers. Inclusion of such fibers into the fabric increases the arc rating/fabric weight ratio of the fabric while still complying with all requisite thermal protective requirements.
Patent AU-2017302668-B2 (AU)
Title: Combination therapies of chimeric antigen receptors and PD-1 inhibitors
Inventor: ANAK OEZLEM
IPC: C07K14/725
Filed: 2017-07-28
Granted: 2023-06-08
Abstract: Provided are compositions and methods for treating diseases, e.g., cancers, e.g., diseases associated with expression of an antigen, e.g., CD 19, comprising administering a cell that expresses a chimeric antigen receptor (CAR) specific to the antigen, e.g., CD19, in combination with a PD-1 inhibitor.
Patent AU-2017329465-B2 (AU)
Title: Device and method for producing pulverulent plastics with a spherical structure
Inventor: DRESSLER AXEL
IPC: B29B9/12
Filed: 2017-09-08
Granted: 2019-09-19
Abstract: The invention relates to a device for producing pulverulent plastics with a structure which is as spherical as possible, having a container (30) which delimits an interior (32); a nozzle device (7) which is arranged in an upper region of the interior (32) and which is connected to a supply delivery line (3) for a hot melt of the product (2), wherein the melt exits the nozzle device (7) and is individualized into small drops which fall into the interior (32); and a supply unit (6) for a cryogas, said supply unit having multiple outlet openings to which the cryogas is supplied in a largely liquid state and out of which a cryogas flow exits into the interior (32), said cryogas flow coming into contact with the small drops. The supply unit (6) is located above or at the same height as the nozzle device (7). According to the method, the hot melt of the product (2) exits the nozzle device (7) in the form of a spray cone, the cryogas flow exits the supply unit (6) in the form of a cone, and the spray cone is located within the cone.
Patent AU-2017343247-B2 (AU)
Title: Refrigerator
Inventor: HEO KWANG SU
IPC: F25D23/06
Filed: 2017-09-25
Granted: 2022-09-15
Abstract: Provided is a refrigerator. More particularly, a refrigerator having a cool air circulation unit for directly supplying heat exchanged cool air to a storage compartment is disclosed. Some of disclosed embodiments provide a refrigerator having a cool air circulation unit for supplying and discharging cool air, which has been heat-exchanged in an evaporator, to a storage compartment through a flow path defined in a partition.
Patent AU-2017357748-B2 (AU)
Title: Improved ice-based lipid nanoparticle formulation for delivery of mRNA
Inventor: DEROSA FRANK
IPC: A61K9/00
Filed: 2017-11-10
Granted: 2023-11-09
Abstract: The present invention provides, among other things, compositions and methods of formulating nucleic acid-containing nanoparticles comprising no more than three distinct lipids components, one distinct lipid component being a sterol-based cationic lipid. In some embodiments, the present invention provides compositions and methods in which the lipid nanoparticles further comprise helper lipids and PEG-modified lipids. The resulting formulation comprises a high encapsulation percentage for nucleic acids.
Patent AU-2017368070-B2 (AU)
Title: Deployable fairing for use with vehicles
Inventor: BURROWS DANIEL
IPC: B62D35/00
Filed: 2017-11-29
Granted: 2021-05-06
Abstract: Systems and methods are disclosed for providing a deployable fairing system to a tractor trailer. The deployable fairing system includes an actuator used to extend the deployable fairing from an unextended configuration to an extended configuration to occupy a portion of a gap area that exists between a tractor and an attached trailer. The deployable fairing includes deployable upper and/or lower horizontal assemblies that are pivotally coupled to a frame attached to the tractor/cab, and two side panels that are pivotally coupled to one or both of the upper and lower horizontal assemblies. The deployable upper and lower horizontal assemblies and the two side panels fold in on one another along multiple hinged axes in the unextended configuration, and extend rearward from the top and sides of the tractor in the extended configuration to cover a portion of the gap. The fairing may advantageously flair from front to the rear.
Patent AU-2017372976-B2 (AU)
Title: Compositions comprising sulfated polysaccharides
Inventor: FRIEDMAN DORON
IPC: A61K31/167
Filed: 2017-12-10
Granted: 2023-12-07
Abstract: The present invention provides a synergistic anti-inflammatory composition comprising one more anti-inflammatory agents such as a steroid, non-steroidal anti-inflammatory drug (NSAID) or a cannabinoid in combination with one or more sulfated polysaccharides. The invention is further directed to a method of treating inflammation and inflammatory diseases using said synergistic composition.
Patent AU-2017383228-B2 (AU)
Title: Modular steamer accessory for steam-heating and/or -cooking food contained in a container
Inventor: GUEGAN LAURENT
IPC: A47J27/04
Filed: 2017-12-18
Granted: 2020-06-25
Abstract: The invention concerns a steamer accessory (4) for steam-heating and/or -cooking food contained in a container, the steamer accessory (4) comprising a steam generator (5) comprising a steam production chamber connected to at least one steam distribution outlet provided in a lower part of the steam generator (5), the steamer accessory (4) comprising a ring (80) carrying the steam generator (5), the ring (80) having a lower surface (81) and an upper surface (82). According to the invention, the ring (80) provides, if so required, with the steam generator (5), at least one vent (90) bringing the lower surface (81) into communication with the upper surface (82). The invention also concerns an electric steamer comprising a container for containing the food to be heated and/or cooked, and a cover forming a steamer accessory (4) according to the above-mentioned features.
Patent AU-2017386900-B2 (AU)
Title: Malware detection and content item recovery
Inventor: ARORA ISHITA
IPC: G06F21/56
Filed: 2017-11-12
Granted: 2019-12-05
Abstract: Disclosed are systems, methods, and non-transitory computer-readable storage media for malware detection and content item recovery. For example, a content management system can receive information describing changes made to content items stored on a user device. The content management system can analyze the information to determine if the described changes are related to malicious software on the user device. When the changes are related to malicious software, the content management system can determine which content items are effected by the malicious software and/or determine when the malicious software first started making changes to the user device. The content management system can recover effected content items associated with the user device by replacing the effected versions of the content items with versions of the content items that existed immediately before the malicious software started making changes to the user device.