baber/WOPTO huggingface dataset:
Patent AU-3105693-A (AU)
Title: Novel compounds and method of preparing a metal-radionuclide-labelled protein
IPC: C07D335/02
Filed: 1993-01-06
Abstract: The invention relates to a method of preparing a protein or a proteinaceous material labelled with a metal-radionuclide and intended for diagnostic or therapeutic application, by reacting a protein or a proteinaceous material with an agent for coupling the radionuclide to the protein or the proteinaceous material, a protein conjugate being formed, and by then complexing the radionuclide with the conjugate thus formed to a radionuclide complex. A coupling agent is used which consists at least substantially of a thio compound of the general formula Y-R-S-X, wherein X is a hydrogen atom or a suitable protective group, R is a branched or non-branched, optionally substituted hydrocarbon radical having 1-10 carbon atoms, which may be interrupted by one or more hetero atoms, and Y is at least one terminal reactive group capable of reacting with a functional group from the protein or the proteinaceous material; or a cyclic condensation product of the thio compound of formula (I) having 5-7 ring atoms, wherein X and Y together constitute a reactive group capable of reacting with a functional group from the protein or the proteinaceous material; or a water-soluble salt of this condensation product. The invention also relates to novel compounds useful as coupling agents and protein conjugates made from them. The invention further relates to the labelled protein or proteinaceous material thus obtained and to a kit for the preparation of a radiopharmaceutical composition which comprises a protein conjuguate formed by reaction of a protern or a proteinaceous material with the coupling agent mentioned hereinbefore.
Patent AU-3121100-A (AU)
Title: Connective tissue growth factor fragments and methods and uses thereof
Inventor: GROTENDORST GARY R
IPC: A61K48/00
Filed: 1999-12-14
Abstract: The present invention is directed to CTGF fragments comprising at least exon 2 or exon 3 of CTGF and having the ability to induce extracellular matrix synthesis, in particular, collagen synthesis and myofibroblast differentiation. The present invention is further directed to methods using said CTGF fragments to identify compositions which modulate the activity of said CTGF fragments and to the compositions so identified. The invention also relates to methods of treating CTGF-associated disorders and diseases associated with the overproduction of the extracellular matrix.
Patent AU-3146599-A (AU)
Title: Demodulator circuits
Inventor: MATTISSON SVEN
IPC: H03D3/22
Filed: 1999-03-19
Abstract: A frequency modulated signal demodulator circuit includes a phase shift element and a time delay element which operate on an input signal (V_IF). The phase shift element and the time delay element are provided by a gyrator component (14, 16, 20).
Patent AU-3186601-A (AU)
Title: Heating element with integrated heat safety device
Inventor: HANTZ PASCAL
IPC: H05B3/48
Filed: 2001-01-10
Abstract: The invention relates to armoured heating elements. The invention specifically relates to a heating device (1) consisting of a tubular envelope, wherein a heating element (4) surrounded by insulation (3) is arranged, said heating element (4) is connected to an electric supply circuit by connecting (14) rods and pins (10,12) and said tubular envelope (2) is provided with two cylindrical sealing beads (16) arranged in the ends thereof, whereby at least one of the beads known as a specific bead (16) is in direct contact with the insulation (3) surrounding the heating element (4); The invention is characterized in that the specific bead (16) comprises an axially transversal recess (18), wherein a thermal fuse (20) is inserted and electrically and serially mounted with said heating element (4).
Patent AU-3209793-A (AU)
Title: Apparatus for teaching downhill skiing on a simulated ski slope
IPC: A63B69/18
Filed: 1993-01-28
Abstract: A ski-deck (10) adapted to be easily knocked down for storage or transport is provided by having telescoping side frames (11) that secure rollers (15, 16) on bearings for a looped carpet over a ski deck and adjustable fitting on vertical support rails (27, 28) secured to horizontal support rails (24, 25) in order to adjust the height and slope of the ski deck. Horizontal safety rails (35, 36) are secured to vertical support rails (27, 28) for a waist belt (41) and ski-grips (42, 43) with a safety switch (44) that will stop the motor drive for the looped carpet. A motor speed control potentiometer (45) is provided on top of a vertical support rail for the ski student's use in adjusting the simulated downhill skiing speed desired. <IMAGE>
Patent AU-3339800-A (AU)
Title: Agent for use in transplantation
Inventor: MOLLER LENNART
IPC: A61K31/4985
Filed: 2000-02-18
Abstract: Use of a compound of formula (I), wherein R1 represents hydrogen or one or several, preferably 1 to 4, similar or different substituents in the positions 1-4 and/or 7-10, selected from halogen, preferably Br, lower alkyl/alkoxy group having not more than 4 carbon atoms, trifluoromethyl group, trichloromethyl group, trichloromethyl group; and in one of the positions 7-10 R1 can be a hydroxyl group; X is a group-(CH2)n-R2, wherein R2 represents a nitrogen containing basic residue such as NH2,NHR4 or NR5R6, wherein R4, R5 and R6 independently are lower alkyl or cycloalkyl and n is an integer of from 1 to 4 and R3 represents hydrogen, lower alkyl/cycloalkyl group having not more than 4 carbon atoms, and the physiologically acceptable addition products of the compounds with acids and halogen adducts, preferably adducts with iodine, iodine monochloride or iodine monobromide, as an agent for protecting tissues, organs and cells in transplantation is described.
Patent AU-3345793-A (AU)
Title: Human kunitz-type protease inhibitor variants
Inventor: BJORN SOREN ERIK
IPC: A61K38/55
Filed: 1993-01-07
Abstract: A variant of the C-terminal Kunitz-type protease inhibitor domain of the  alpha 3 chain of human type VI collagen, the variant comprising the following amino acid sequence X1 X16 Asp Ile Cys Lys Leu Pro Lys Asp X2 Gly X3 Cys X4 X5 X6 X7 X8 X9 Trp Tyr Tyr Asp Pro Asn Thr Lys Ser Cys Ala Arg Phe X10 Tyr Gly Gly Cys X11 X12 X13 Glu Asn Lys Phe X14 Ser Gln Lys Glu Cys Glu Lys Val Cys Ala Pro X15 (SEQ ID NO. 1) wherein X1, X15, and X16 represents a naturally occurring amino acid residues except Cys and X2-X14 each independently respresents a naturally occurring amino acid residue, with the proviso that at least one of the amino acid residues X1-X16 is different from the corresponding amino acid residue of the native sequence. Alternatively, the N-terminal Asp may be preceded by H or 3-5 amino acid residues and the C-terminal Pro may be followed by OH or 3-5 amino acid residues.
Patent AU-3424795-A (AU)
Title: A turbocharger assembly
Inventor: RAMSDEN JOHN NIGEL
IPC: F02B39/14
Filed: 1995-10-13
Abstract: A turbocharger module (100) for a turbocharged internal combustion engine comprises turbocharger cartridges (850), each having a turbine rotor (814) and a compressor impeller (812) mounted on a common shaft (816) running in bearings (809). Each cartridge is held in a bore (851) in a wall (90) of a supporting enclosure (9), with its turbine rotor projecting into the enclosure and its compressor impeller outside the enclosure. A turbine housing (800) is fitted tightly to an internal wall surface region (807) surrounding each bore to provide a low thermal resistance path to heat flow by conduction from the turbine housing (800) into the wall (90). When installed in the bores, the turbine rotors of the cartridges fit into the turbine housings, the cartridges being held concentric with the turbine housing by a spigot (870) having a close fit in a circular register (871) in the turbine housing. The spigot and the register contact each other over an annular region which is substantially smaller in area than the area of contact between the turbine housing (800) and the internal wall surface region (807), the spigot and the register providing the only significant region of direct mechanical contact between the turbine casing (800) and the cartridge (850). Hence, during operation of the cartridges, heat from the turbine casing is shunted away from the cartridges into the wall (90) of the enclosure (9). Preferably, the wall is actively cooled. <IMAGE>
Patent AU-3434693-A (AU)
Title: Oxidation of glycolic acid to glyoxylic acid using a microbial cell transformant as catalyst
Inventor: ANTON DAVID LEROY
IPC: C12R1/78
Filed: 1993-01-06
Abstract: A process for the production of Glyoxylic acid from glycolic acid where an aqueous solution of about 200 to 2500 mM glycolic acid at a pH of 7 to 10, at 0 DEG  to 40  DEG C is contacted with an effective amount of whole microbial cells (e.g., Aspergillus nidulans, Pichia pastoris, Hansenula polymorpha and Escherichia coli) which as a result of genetic engineering expresses the enzyme glycolate oxidase, (S)-2-hydroxy-acid oxidase (EC 1.1.3.15), to achieve an effective concentration range of 0.01 to about 100 IU/mL and optionally expresses an endogenous catalase (EC 1.11.1.6).
Patent AU-3654795-A (AU)
Title: Signal detection in a tdma system
Inventor: HOTTINEN ARI
IPC: H04J3/00
Filed: 1995-10-05
Abstract: PCT No. PCT/FI95/00551 Sec. 371 Date Apr. 7, 1997 Sec. 102(e) Date Apr. 7, 1997 PCT Filed Oct. 5, 1995 PCT Pub. No. WO96/11533 PCT Pub. Date Apr. 18, 1996A signal detection method in a TDMA mobile system with co-channel interference and receivers implementing the method. In the method, a primary signal (r1) and at least one interfering co-channel signal (r2-rN) are received on the same TDMA channel (F1, TS3). The co-channel signals propagate through multipath channels (hL,1 . . . hL,N) independent of one another, which provide them with a unique wave form coding. In addition, the co-channel signals have different but known training sequences. The multipath channel estimates of the primary signal (r1) and the at least one interfering co-channel signal (r2-rN) are determined through the received training sequences. After this, the primary signal is detected by utilizing the transmission channel estimates of both the primary signal and the at least one interfering co-channel signal.
Patent AU-3750793-A (AU)
Title: Suction catheter
Inventor: SCHON RUDOLF
IPC: A61M16/04
Filed: 1993-03-19
Abstract: The suction catheter tube with continuous lumen connects proximal to a connector, etc. and is reinforced outside at the distal end in ring form and has here equi-spaced radial openings round the tube. The distal outlet (21) of lumen (13) is of funnel form in relation to the remaining lumen sections so the funnel shape is expanded by two equi-spaced peripheral notches (22,23) in the radial sense reaching into the lumen. The distal outlet (21) terminates in an axial beading (20).
Patent AU-3805699-A (AU)
Title: An automotive seat assembly having an integral tear seam
Inventor: PERSHA SEAN
IPC: B60R21/2165
Filed: 1999-05-21
Abstract: An automotive seat assembly is provided with an integrated side impact airbag. The seat assembly comprises a seat cushion and a seat back mounted to the seat cushion. A seat cushion trim cover material covers the seat cushion and a seat back trim a cover material covers the seat back. The seat assembly is characterized by a tear seam integrally formed within a bolster section of the seat back trim cover material. The tear seam defines a frangible line of weakness within the trim cover material wherein the airbag will tear through the tear seam when the airbag is deployed and inflated to a position outside of the seat assembly. The subject invention also includes a manufacturing apparatus for forming the tear seam in the trim cover material. The apparatus comprises a template (48) supporting the trim cover material (28). A C-shaped raised ridge (50) extends upwardly from the template to abut the inside surface of the trim cover material (28). A welder (52) is disposed adjacent the outside surface of the trim cover material (28) such that the trim cover material is wedged between the template (48) and the welder (52). The welder is aligned with the raised ridge to form the tear seam within the trim cover material.
Patent AU-3833095-A (AU)
Title: Non-volatile adhesive promoter composition for curing adhesives
Inventor: LIU JU-CHAO
IPC: B05D7/24
Filed: 1995-10-13
Abstract: A non-environmentally hazardous, non-volatile adhesive promoter composition useful in promoting the cure and/or enhancing adhesion of adhesives and for use in combination with adhesive bond polymerization. The promoter composition is a combination of a fluid carrier that remains substantially present during the curing of an adhesive composition and an active component capable of promoting the cure and/or enhancing adhesion of the adhesive and being miscible in the fluid carrier.
Patent AU-3922289-A (AU)
Title: Process and agent for the colorimetric determination of an analyte by means of enzymatic oxidation
Inventor: HOENES JOACHIM
IPC: C12Q1/32
Filed: 1989-08-02
Abstract: The invention relates to a method for the colorimetric determination of an analyte by means of enzymatic oxidation of the analyte in the presence of an electron acceptor and determination of the reduced electron acceptor by colour formation as a measure of the amount of the analyte, characterised in that the analyte is oxidised with an appropriate oxidoreductase in the presence of a substance from the group of compounds with nitrogen in an oxidation state between +1 and -1 as direct electron acceptor, and an agent suitable for this purpose. 
<IMAGE>
Patent AU-4291100-A (AU)
Title: Short-chain peptide dye conjugates used as contrast agents for optical diagnostics
Inventor: LICHA KAI
IPC: C09B23/08
Filed: 2000-03-28
Abstract: Conjugates (I) of vasoactive intestinal peptide (VIP), somatostatin or neurotensin peptides and polymethine dyes are new. Peptide-dye conjugates of formula (I) are new. X = a sequence of 5-30  alpha -,  beta - or  gamma -amino acids (D or L) corresponding to the amino acid sequence of VIP, somatostatin or neurotensin or a fragment, derivative or analog thereof, optionally cyclized by a disulfide bridge between two cysteines or by an amide bridge between the N and C termini; A<1> = H, acetyl, 1-10C alkyl (optionally substituted by 1-3 COOH groups and/or 1-6 OH groups), a polyoxyethylene group comprising 2-30 CH2CH2O units, or a polymethine dye having at least one absorption maximum in the 380-1200 nm range; and A<2> = OH, NH2 or a polymethine dye having at least one absorption maximum in the 380-1200 nm range; provided that at least one of A<1> and A<2> is a polymethine dye, that when A<1> is a polymethine dye, it is bonded to the N-terminal amino group and that when A<2> is a polymethine dye, it is bonded to a lysine amino group or serine hydroxy group at any position within X. Independent claims are also included for the following: (1) a diagnostic method comprising administering (I) to a patient, either intravenously or to the bronchi by inhalation or to the gastrointestinal tract, esophagus or bladder by spraying and then washing out excess (I), and then performing an endoscopic investigation by local excitation of fluorescence at an excitation wavelength of 350-1200 nm and site-specific detection of the fluorescence emitted by the dye; and (2) cyanine dyes of formula (II). p = 1-3; n = 1-4 or 10; R<1>, R<2> = 4-sulfobutyl, 3-sulfopropyl, 2-sulfoethyl, 3-methyl-3-sulfopropyl, methyl, ethyl or propyl; R<3> = H, COOE<1>, CONE<1>E<2>, NHCOE<1>, NHCONHE<1>, NE<1>E<2>, OE<1>, OSO3E<1>, SO3E<1> or SO2NHE<1>; and E<1>, E<2> = H, CH3, ethyl, or 3-6C alkyl optionally interrupted by 1-2 O atoms and/or a CO group and/or optionally substituted by 1-5 OH groups.
Patent AU-4322996-A (AU)
Title: Variants of human papilloma virus antigens
Inventor: EDWARDS STIRLING JOHN
IPC: C12N15/37
Filed: 1995-12-20
Abstract: Variants of human papilloma virus (HPV) E6 and E7 proteins able to elicit a humoral and/or cellular immune response against HPV in a host animal but not being cell-transforming in the host animal are disclosed, and are useful in treatment or prevention of diseases or conditions involving HPV.
Patent AU-4327797-A (AU)
Title: Long wavelength engineered fluorescent proteins
Inventor: TSIEN ROGER Y
IPC: C07H21/04
Filed: 1997-08-15
Abstract: Engineered fluorescent proteins, nucleic acids encoding them and methods of use. <IMAGE> <IMAGE>
Patent AU-4365689-A (AU)
Title: Process for the determination of antibodies which are class-specific for an antigen and a reagent for carrying out the process
Inventor: SCHMITT URBAN
IPC: G01N33/576
Filed: 1989-10-23
Abstract: To determine antibodies of a particular immunoglobulin class which are directed against an antigen A in body fluids by the immunoassay principle by incubation of the sample solution with at least two receptors R<1> and R<2>, of which R<1> can be immobilised and is able to bind to the antibody to be determined, and R<2> is labelled and is able to bind either to the antibody to be determined or to the antigen A, separation of the solid from the liquid phase and measurement of the labelling in one of the two phases, the immunological reaction is carried out in homogeneous phase and the sample solution is incubated simultaneously with receptor R<1> and an excess of human antibodies which belong to the same immunoglobulin class as the antibodies to be determined and are not able to bind to the antigen A, and subsequently receptor R2 and, where appropriate, other receptors are added.
Patent AU-4458997-A (AU)
Title: Heating conductor for a cooking plate
Inventor: DITTMAR GUNTER
IPC: H05B3/74
Filed: 1997-09-16
Abstract: PCT No. PCT/EP97/05055 Sec. 371 Date Mar. 19, 1999 Sec. 102(e) Date Mar. 19, 1999 PCT Filed Sep. 16, 1997 PCT Pub. No. WO98/12898 PCT Pub. Date Mar. 26, 1999A heating conductor which can be fitted in a geometrical pattern into a radiant heating body is to be easy to fit and is to have good radiation properties. The heating conductor is separated in the form or partial form of the geometrical pattern out of a metal foil and forms heating limbs (1). In the geometrical pattern there are stabilisation limbs (5) whose width is less than the width of the heating limbs (1) in such a way that they can burn through upon the application of an electrical voltage which is harmless to the heating limbs (1).
Patent AU-4574399-A (AU)
Title: Method and apparatus for controlling airflow
Inventor: PRZILAS MARK B
IPC: H05K7/20
Filed: 1999-06-16
Abstract: Airflow patterns from fans and centrifugal blowers that force air into cardcages may be very irregular and unpredictable. Because the amount of cooling provided by fans and centrifugal blowers is based directly upon the velocity of air over the components of the circuit cards within the cardcages, irregular airflow patterns may lead to unreliable operation of circuit cards due to inadequate cooling. In a broad aspect, the present invention comprises a system for controlling the temperatures of circuit cards in cardcages or other enclosures by controlling the flow of air. More particularly, the invention comprises mechanical flow diverters which may divert, deflect, channel or otherwise re-distribute the flow of air to attain a generally common or consistent rate of flow past each circuit card in a cardcage. The invention may be assembled as a discrete part and attached either to the fan, cardcage or other support structure or the invention can be an integral part of the cardcage. The invention maximizes cooling efficiency by modifying the cooling air distribution based on actual requirements and these requirements are proportional to the local heat flux and/or device temperature limits.
Patent AU-4631197-A (AU)
Title: Detecting genetic predisposition to sight-threatening diabetic retinopathy
Inventor: DUFF GORDON
IPC: C12Q1/6883
Filed: 1997-10-09
Abstract: A method and kit for predicting increased risk of sight-threatening diabetic retinopathy which includes isolating genomic DNA from a sample from a diabetic patient. The genetic polymorphism pattern for the genes IL-1A, IL-1B and IL-1RN is then identified in the DNA. The identified pattern is compared with control patterns of known polymorphisms, and patients expressing a genetic polymorphism pattern associated with increased risk of sight-threatening diabetic retinopathy are identified.
Patent AU-4680601-A (AU)
Title: Device for trimming and automatic cutting of images on paper and other graphic and photographic substrates, in particular of large size
Inventor: MADDALON VALTER
IPC: B26D7/26
Filed: 2001-03-15
Abstract: A device for trimming and automatically cutting of either multiple or single images is described produced for example through digital rendering on paper and other graphic and photographic substrates, wound in reel or being in single sheets (10), especially of large size. The problems met in using known devices of this type with feeding rollers (2) with a length corresponding to the substrate width have the consequence of a slowing down of the production owing to the excessive care to be taken when introducing at the same time parallel sheets of large size. These problems can be overcome by using rollers of reduced length, but only by adding errors in the forward movement of the substrate, errors which are remedied by means of optical sensors (4, 4') for detecting the separation mark (M) between the images (10a, 10b, .....) as well as its angle with respect to the cutting line (7), and by a pair of length differences measuring devices (6).
Patent AU-4769785-A (AU)
Title: Unsaturated polysiloxanes, polymerizable compositions and contact lenses thereof
Inventor: MUELLER KARL FRIEDRICH
IPC: C08G77/20
Filed: 1985-09-23
Abstract: Polysiloxanes of uniform molecular weight (MW) distribution with 500-10,000 MW segments of polysiloxane and containing at least one vinyl group connected to said polysiloxane segments through intervening alkylene-urea or -urethane linkages are prepared from polysiloxane-polyols, -polyamines or -polythiols by reaction with an unsaturated compound containing an isocyanato moiety, for example 2-isocyanatoethyl methacrylate. The polysiloxanes containing the vinyl groups are useful as radiation- or thermally curable coatings for glass, textiles, plastics, wood, ceramics, metals, as films or bandages for medicinal purposes, or molded shapes, in form of contact lenses, catheters or implants, either by themselves or in combination with other vinyl monomers; and are particularly useful in preparing hard or soft contact lenses, including hydrogel contact lenses.
Patent AU-4819999-A (AU)
Title: A method for inducing production of growth factors
Inventor: ITO MASAYO
IPC: C12N5/071
Filed: 1999-06-23
Abstract: A method of enhancement of growth factors including PDGF, which enables them to be used in the treatment of bone fractures and wounds in the future. The more efficient production of growth factors in this invention can be applied as a therapeutic agent for fracture and/or wound healing.
Patent AU-4876597-A (AU)
Title: Notch
Inventor: LAMB JONATHAN ROBERT
IPC: C07K14/725
Filed: 1997-11-06
Abstract: The present invention relates to the use of therapeutic compounds in the modification of T-cell, T-cell-antigen presenting cell (APC) interactions and the interactions between pathogenic organisms and immunocompetent cells of a host. In particular it relates to the use of these compounds in the modulation of the interaction between  Notch  proteins and their ligands and to the use of such compounds in the therapy of conditions such as graft rejection, autoimmunity, allergy, and asthma and infectious diseases.