baber/WOPTO huggingface dataset:
Patent CA-2557904-A1 (CA)
Title: Hiv integrase inhibitors
Inventor: WILLIAMS PETER D
IPC: C07D411/00
Filed: 2005-03-04
Abstract: Compounds of Formula I are inhibitors of HIV integrase and inhibitors of HIV  replication: (I) wherein Z, R1, R2, R3, R4, R5, R6, R7, R8 and R9 are defined herein. The compounds are useful in the prevention and treatment of infection by HIV and in the prevention, delay in the onset, and treatment of AIDS. The compounds are employed against HIV infection and AIDS as compounds per se or in the form of pharmaceutically acceptable salts. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines.
Patent CA-2559515-A1 (CA)
Title: Unidimensional array 3-d position sensitive ionization detector
Inventor: BRYMAN DOUGLAS
IPC: G01T1/24
Filed: 2005-03-18
Abstract: The present invention provides an improved gamma ray detector module (300) and a method of operating such a detector module (300) for more accurately determining the position of a gamma ray interaction (340) within a detector (304). The detector module (300) includes an induction array (311) arranged at an offset angle relative other arrays utilized in the detector (304), whereby the relative timing of the detection of ionization electrons (360) by the induction array (311) and a collector or anode (310) indicate at least one coordinate corresponding to the location of the interaction (340) that produced the ionization electron (360). This secondary locating apparatus and method supplements or replaces conventional locating apparatus and methods for improving the accuracy or reducing the complexity of the detection apparatus.
Patent CA-2560226-A1 (CA)
Title: Pharmaceutical formulations for dry powder inhalers comprising a low-dosage strength active ingredient
Inventor: RASTELLI ROBERTO
IPC: A61K9/50
Filed: 2005-03-16
Abstract: The invention provides a formulation to be administered as dry powder for inhalation suitable for efficacious delivery of low-dosage strength active ingredients to the low respiratory tract of patients. In particular, the invention provides a formulation comprising microparticles constituted of microparticles of a low-dosage strength active ingredient and microparticles of an excipient wherein the MMD of the microparticles is comprised between 2 and 15 micron, at least 10% of the microparticles has a mass diameter (MD) higher than 0.5 micron, and the process of preparation thereof.
Patent CA-2560248-A1 (CA)
Title: Pressure-sensitive adhesive for motor vehicle brake disc antirust film
Inventor: MATSUBAYASHI YUMIKO
IPC: C09J7/02
Filed: 2005-03-22
Abstract: A pressure-sensitive adhesive agent for an automobile brake disc antirust film, which comprises an acrylic resin based pressure-sensitive adhesive agent being obtained by crosslinking an acrylic copolymer containing a unit based on a (meth)acrylamide based monomer and having a weight average molecular weight of 500,000 to 1,100,000 with a polyisocyanate compound by the utilization of the unit based on a (meth)acrylamide based monomer as a crosslinking base point. The above pressure-sensitive adhesive agent can provide an automobile brake disc antirust film which is difficult to peel off when pasted on a wheel of an automobile.
Patent CA-2561192-A1 (CA)
Title: Cancerous disease modifying antibodies
Inventor: KELLEHER MICHELLE
IPC: G01N33/567
Filed: 2005-03-29
Abstract: The present invention relates to a method for producing patient cancerous disease modifying antibodies using a novel paradigm of screening. The antibodies can be used in aid of staging and diagnosis of a cancer, and can be used to treat primary tumors and tumor metastases. The anti-cancer antibodies can be conjugated to toxins, enzymes, radioactive compounds, and hematogenous cells. The invention further relates to such diagnosis and treatment which revolves around the ability of the 5LAC~23 monoclonal antibody (or antigenic binding fragments derived therefrom) to bind with the Laminin Receptor 1 Precursor Protein 37LRP; and most particularly to diagnosis and treatment of Hepatocellular Carcinoma by various means which rely upon direct binding of 5LAC-23 with the particular antigenic moiety specifically recognized thereby and generally overexpressed in Hepatocellular carcinoma cells.
Patent CA-2561228-A1 (CA)
Title: Method and apparatus for providing virtual private access links in a communication network
Inventor: CROAK MARIAN
IPC: H04L12/24
Filed: 2006-09-27
Abstract: A method and apparatus for providing an overlay structure in the access portion of a packet network, e.g., a VoIP network, that allows enterprise customers to place their traffic on virtual private links for both signaling and media traffic are disclosed. The method partitions the VoIP access network components so that only subscribers of private access lines can use the virtual private traffic links across the infrastructure. These private links provide the highest quality of service backed by SLA and prioritize the traffic of subscribers of private access lines over any other traffic that is being transmitted.
Patent CA-2565072-A1 (CA)
Inventor: ELLMAN STEVEN
IPC: A63H13/00
Filed: 2005-06-01
Abstract: An expression mechanism for a toy having a lower lip, a cheek and an eye, includes a support frame, a lip lever pivotally connected to the support frame for engaging the lower lip of a toy, a cheek lever pivotally connected to the support frame for engaging a cheek of the toy, an eye linkage for opening or closing the eye of the toy, and a motor for actuating one of the lip and cheek levers to cause the toy to simulate a facial expression. The lip and cheek levers are interconnected in a manner that when the cheek lever pivots in one direction, the lip lever pivots in a generally opposite direction. The expression mechanism causes the toy to assume various facial expressions, including, but not limited to, smile, frown, and neutral.
Patent CA-2566047-A1 (CA)
Inventor: NIES JAMES GORDON
IPC: H04M3/51
Filed: 2006-10-30
Abstract: Disclosed in various embodiments are various systems, methods, and programs embodied on a computer readable medium for automated scoring of interactions.  In one embodiment, an example of a method is provided that comprises the steps of storing a plurality of interactions in a memory, wherein a plurality of interactive factors are memorialized for each of the interactions, each of the interactive factors comprising an aspect of the interaction. The method also comprises the steps of applying a plurality of rules to each of the interactions to identify a plurality of events in each of the interactions, each of the rules defining at least one event that is associated with at least one of the interactive factors of a respective one of the interactions, and, generating a score in the computer system for each of the interactions based upon the rules defining the at least one event occurring in each of the interactions, respectively.  The method further comprises the step of ranking at least a subset of the interactions relative to each other based upon the scores generated for the interactions.
Patent CA-2567411-A1 (CA)
Inventor: MATSUHISA KEIICHI
IPC: A61K31/722
Filed: 2005-05-30
Abstract: A highly safe means of improving the visibility of a transparent tissue in eye such as vitreous body, crystal lens or cornea in operating the same. This means contains fine particles made of a polymer compound, in particular, fine particles 1 g of which are not completely dissolved in less than 30 mL of water at 20oC within 30 minutes and which have an average particle diameter of from 0.01 to 500 µm, among all, fine particles made of a biodegradable polymer compound and/or a water-soluble polymer compound.
Patent CA-2567635-A1 (CA)
Inventor: ALSINA-FERNANDEZ JORGE
IPC: C07K14/575
Filed: 2005-05-19
Abstract: The present invention encompasses peptides that selectively activate the VPAC2 receptor and are useful in the treatment of diabetes.
Patent CA-2568730-A1 (CA)
Inventor: KARL A ROBERT
IPC: A61C17/22
Filed: 2005-06-08
Abstract: A conventional electric toothbrush of the type having a vibrating brush head mounted on a battery operated hand unit is modified so that its bristles can be replaced without replacing the entire bristle head. The bristle head includes a first shaft having a proximal end and a distal end, bristles mounted on the distal end of the first shaft, and means for releasably mounting the first shaft on the hand unit and for responding to a force produced by the hand unit by vibrating the first shaft. The bristle head is modified by cutting or otherwise dividing the first shaft to remove the distal end holding the bristles, and then releasably coupling a replacement brush (26) to the new distal end of the first shaft, the replacement brush including a second shaft having a distal end and a proximal end and bristles mounted on the distal end, the proximal end of the second shaft being releasably coupled to the new distal end of the first shaft.
Patent CA-2568761-A1 (CA)
Inventor: ANDERSON IAN
IPC: B67D1/12
Filed: 2005-05-20
Abstract: A valve assembly for filling a bag with a beverage under pressure has a valve body having a first passageway extending therethrough and a first valve seated in the first passageway for controlling the flow of beverage through the first passageway into and out of the bag. A pressure relief passageway extends through the valve body from inside the bag to within the container. A bursting disk is seated with the valve body normally closing the pressure relief passageway and is adapted to rupture permitting fluid to escape from the bag through the pressure relief passageway and into the container surrounding the bag when the pressure in the bag exceeds a predetermined pressure value.
Patent CA-2573198-A1 (CA)
Inventor: SUN SHAOYI
IPC: A61P43/00
Filed: 2004-07-06
Abstract: Methods of treating an SCD-mediated disease or condition in a mammal, preferably a human, are disclosed, wherein the methods comprise administering to a mammal in need thereof a compound of formula (I): where m, n, p, V, R1, R2, R3, R4, R5 and R6 are defined herein. Pharmaceutical compositions comprising the compounds of formula (I) are also disclosed.
Patent CA-2575832-A1 (CA)
Inventor: CUPPLES KENNETH ALAN
IPC: B65B1/04
Filed: 2005-08-10
Abstract: A method and apparatus are provided for monitoring a liquid level in a closed tank with a differential pressure sensor module disposed in a bottom portion of the tank, by routing a pressure reference tube extending from the pressure sensor module through the interior of the tank and attaching an opposite, open, vented end of the pressure reference tube to the tank at a point inside of the tank in an upper portion of the tank.
Patent CA-2575839-A1 (CA)
Title: Biological specimen collection, transportation, and dispensing system
Inventor: YONG PETER A K
IPC: B32B5/02
Filed: 2005-07-29
Abstract: A body fluid collecting, transporting, and dispensing system includes a body fluid collecting receptacle and a handle for supporting the receptacle in a fluid collection position. The handle includes a fluid sample chamber in fluid communication with the receptacle to receive a sample of the body fluid and the handle is further removable from the receptacle for transport and dispensing of the body fluid sample.
Patent CA-2580226-A1 (CA)
Title: Continuous flowing pre-treatment system with steam recovery
Inventor: REA DAVID
IPC: B09B3/00
Filed: 2005-09-30
Abstract: The present invention is directed to a continuous process for pretreating a lignocellulosic feedstock. A feedstock slurry is provided, which has a solids concentration of 10% to 30% by weight. The feedstock slurry is pumped through a heating train of at least two stages, each stage including a pump to increase stage pressure and a direct steam injection to heat the feedstock slurry. Acid is also added to the feedstock slurry prior to the heating train, during a heating stage, or after leaving the heating train; the acid is added at a concentration of 0.2% to 12% weight of acid on weight of initial feedstock. A heated, acidified feedstock slurry is thus produced. The heated, acidified feedstock slurry is flowed through a pre-treatment reactor at a temperature of 160~C to 280~C for a time sufficient to increase efficiency of conversion of cellulose in the feedstock to glucose using cellulase enzymes.  After the slurry exits the pre~treatment reactor, it is cooled using two, or more than two flashing stages at successively lower pressures, without increasing the steam pressure after flashing. The steam energy, at or near its flash pressure, from two or more than two of the flashing stages is used to heat the feedstock slurry in the heating train.
Patent CA-2582480-A1 (CA)
Inventor: PETERSEN LUIS
IPC: B02C4/42
Filed: 2006-06-12
Abstract: Described is a roller mill (1) for grinding particulate material such as cement raw materials, cement clinker and similar materials, said roller mill(l) comprising a housing (3) which surrounds a grinding table (7) which is rotatable about a vertical axis (5) , said grinding table being supported via a support (9) by a machine foundation (11) , at least one roller (13) rotatable about a substantially stationary axis (12) , said roller being configured for interaction with the grinding table (7) and an electric motor (15) , which comprises a rotor (16) which is firmly connected to the grinding table (7) and a stator (17) . The roller mill is peculiar in that the stator (17) constitutes an integral part of the support (9) for the grinding table (7) , so that at least some of the load imposed by the at least one roller (13) on the grinding table (7) is transmitted via the stator (17) to the machine foundation (11) .
Patent CA-2583747-A1 (CA)
Inventor: MAZZA ALEX TRUMAN
IPC: A61M1/00
Filed: 2005-10-21
Abstract: L'invention concerne un dispositif de régulation de fluide permettant de diriger un écoulement fluidique qui comprend un dispositif d'accès sans aiguille permettant de transférer des fluides, et des procédés permettant de diriger un écoulement fluidique. Le dispositif de régulation de fluide de l'invention peut comprendre un premier, un deuxième, un troisième port et une partie de connexion qui assemble les premier, deuxième et troisième ports. Un premier élément valve peut être positionné à l'intérieur du premier port et un élément de guidage de fluide peut être positionné à l'intérieur de la partie de connexion. Le premier élément valve peut se déplacer entre une position ouverte, dans laquelle le fluide peut s'écouler après le premier élément valve, et une position fermée, dans laquelle d'écoulement de fluide peut être retenu après ledit premier élément valve. L'élément de guidage de fluide peut comprendre au moins un passage permettant de relier au moins deux des premier, deuxième et troisième ports de sorte que le fluide puisse passer entre ceux-ci. Un mécanisme d'actionnement peut être utilisé pour orienter l'élément de guidage de fluide et, par conséquent, le ou les passages à l'intérieur de la partie de connexion.
Patent CA-2585932-A1 (CA)
Inventor: HARRISON DAVID A
IPC: C08L23/10
Filed: 2005-11-01
Abstract: Reheat characteristics of polyethylene and polypropylene resins, including reheating time and resin color, are improved by adding to the resin carbon black with a primary particle size in the range of 200 to 500 nm as an infrared absorber. Thermal carbon blacks having this primary particle size are preferred over Furnace carbon blacks. Injection stretch-blow molded bottles and other thermoformed products are made from resins with carbon black infrared absorber.
Patent CA-2591389-A1 (CA)
Title: Reinforced and drug-eluting balloon catheters and methods for making same
Inventor: HOLMAN THOMAS J
IPC: A61F2/958
Filed: 2005-10-12
Abstract: The present invention generally relates to the field of intravascular medical devices, and more specifically to the field of balloon catheters and other similar diagnostic or therapeutic catheters within the body for treatment and diagnosis of diseases. In particular, the present invention relates to reinforced balloon catheters and drug-eluting balloon catheters and corresponding methods for producing same.
Patent CA-2592177-A1 (CA)
Inventor: LU JIAN-FENG
IPC: C07K16/32
Filed: 2005-06-15
Abstract: The present invention concerns fixed dosing of HER antibodies, such as Pertuzumab.
Patent CA-2592466-A1 (CA)
Inventor: KIM HYUN-KEE
IPC: C07K14/47
Filed: 2005-12-28
Abstract: Disclosed are a novel protooncogene and a protein encoded therein. The protooncogene of the present invention, which is a novel gene that takes part in human carcinogenesis and simultaneously has an ability to induce cancer metastasis, may be effectively used for diagnosing the cancers, including lung cancer, leukemia, uterine cancer, lymphoma, colon cancer, skin cancer, etc., as well as producing transformed animals, etc.
Patent CA-2593908-A1 (CA)
Title: Process for the preparation of polymer conjugates
Inventor: GREENWALD RICHARD B
IPC: A61K47/48
Filed: 2006-01-31
Abstract: A process for efficiently preparing polymer conjugates such as branched PEG-polypeptide conjugates, in large scale without column chromatography clean up of the activated PEG linkers to remove impurities is disclosed.
Patent CA-2594339-A1 (CA)
Inventor: HUANG XIAOJUN
IPC: G01V3/00
Filed: 2005-12-22
Abstract: A method and apparatus for estimating slowness by developing an objective function called a formation slowness curve and determining its local maxima or minima (100).
Patent CA-2598507-A1 (CA)
Title: Support de tige de forage, et moitie de support de tige de forage
Inventor: FRANZEN HAKAN
IPC: E21B19/24
Filed: 2006-02-28
Abstract: Support de tige de forage (10) comprenant un système capable de déplacer deux moitiés opposées de support de tige de forage (20), chaque moitié (20) dotée d'une surface (21) de contact direct avec le train de tiges (30), ladite moitié étant par ailleurs dotée d'une cavité (23) capable de former une ouverture de train de forage (22) avec une moitié opposée de support de tige de forage (20), cette cavitéétantgénéralement en forme de V, pour le guidage de trains de tiges (30) de différentes formes et dimensions. Les moitiés de support de tige de forage (20) sont mobiles l'une par rapport à l'autre, permettant le contact avec le train de tiges (30) L'invention concerne également une moitié de support de tige de forage (20) destinée à être utilisée dans le type de support de tige de forage considéré.
Patent CA-2598625-A1 (CA)
Inventor: VAN KANN FRANK JOACHIM
IPC: G01V7/16
Filed: 2006-08-31
Abstract: A gravity gradiometer is disclosed which has a sensor in the form of bars (41 and 42) which are supported on a mounting (5) which has a first mount section (10) and a second mount section (20). A first flexure web (33) pivotally couples the first and second mount sections about first axis. The second mount has first part (25), a second part (26) and a third part (27). The parts (25 and 26) are connected by second flexure web (37) and the parts (26 and 27) are connected by third flexure web (35). The bars (41 and 42) are located in housings (45 and 47) and form a monolithic structure with the housings (45 and 47) respectively. The housings (45 and 47) are connected to opposite sides of the second mount section 20. The bars (41 and 42) are connected to their respective housings by flexure webs (59).
Patent CA-2598969-A1 (CA)
Title: 6, 7, 8, 9-tetrahydro-5-amino-5h-benzocyclohepten-6-ol derivatives and related compounds used as anti-inflammatory agents
Inventor: BERGER MARKUS
IPC: C07D211/88
Filed: 2006-03-20
Abstract: The invention relates to polysubstituted 5H-benzocyclohepten derivatives of formula (I), in which R3 represents a C1-C10 alkyl group, which can be optionally substituted by a group selected from 1-3 hydroxy groups, halogen atoms, or 1-3 (C1-C5) alkoxy groups, an optionally substituted (C3-C7) cycloalkyl group, an optionally substituted heterocyclyl group, an optionally substituted aryl group, or other substituents, A represents a -CR6R7-CH2- or -CH2-CR6R7 group, D represents a -CR4R5-CH2- or -CH2-CR4R5 group, R4 represents a hydroxy group, an OR10 group or O(CO)R10 group, R5 represents a (C1-C5) alkyl group or an optionally partially or completely fluorinated (C1-C5) alkyl group, a (C3-C7) cycloalkyl group, a (C1-C8) alkene (C3-C7) cycloalkyl group, a (C2-C8) alkene (C3-C7) cycloalkyl group, a heterocyclyl group, a (C1-C8) alkene heterocyclyl group, a (C2-C8) alkene heterocyclyl group, an aryl group, a (C1-C8) alkene aryl group, a (C2-C8) alkenylene aryl group, a (C2-C8) alkynylene aryl group, or other substituents. Said other substituents are specified in the claims. The invention also relates to a method for producing said derivatives and to their use as anti-inflammatory agents.
Patent CA-2599232-A1 (CA)
Inventor: KELLER BRIAN CHARLES
IPC: C10G1/04
Filed: 2007-08-28
Abstract: PEG lipids are used to extract hydrocarbons from oil sands. At ambient temperatures the PEG lipids combine with bitumen onto a flowable form, which is easily transportable by pipeline. The process results in the release of less carbon dioxide than conventional extraction processes.
Patent CA-2599293-A1 (CA)
Title: Touch sensitive display having tactile structures
Inventor: GRIFFIN JASON T
IPC: G06F3/048
Filed: 2007-08-29
Abstract: An improved handheld electronic device has a touch sensitive display which comprises a number of elongated tactile structures that are haptically detectable by a user. Various routines executable on the handheld electronic device can cause visual elements to be output in various predetermined arrangements with respect to the arrangement of the tactile structures in order to facilitate input.
Patent CA-2599710-A1 (CA)
Inventor: ZHAO DALIAN
IPC: A01N43/38
Filed: 2006-03-10
Abstract: Novel crystalline forms of two indole compounds connected to phenoxyalkylcarboxylic acid groups are selective PPAR gamma partial agonists that are useful in the treatment of type 2 diabetes, hyperglycemia, obesity, dyslipidemia, and the metabolic syndrome. The novel crystal forms include a crystalline free acid dihydrate and crystalline free acid anhydrate of one compound and several crystalline forms of the free acid and the sodium salt of the second compound. The invention also relates to pharmaceutical compositions comprising these novel crystal forms, processes to prepare the crystal forms and their pharmaceutical compositions, and uses of the crystal forms in the treatment of type 2 diabetes and other PPAR gamma modulated diseases.
Patent CA-2601875-A1 (CA)
Title: Natural deodorant compositions comprising renewably-based, biodegradable 1.3-propanediol
Inventor: RATNIKOVA SVETLANA
IPC: A61Q15/00
Filed: 2007-02-12
Abstract: Disclosed herein are all natural or substantially natural deodorant and antiperspirant compositions comprising 1,3-propanediol wherein the 1,3-propanediol in said all natural or substantially natural deodorant or antiperspirant composition has a bio-based carbon content of about 1% to 100%.  In addition, it is preferred that the 1,3-propanediol be biologically-derived, and wherein upon biodegradation, the biologically-derived 1,3-propanediol contributes no anthropogenic CO2 emissions to the atmosphere.
Patent CA-2605881-A1 (CA)
Title: Orthopedic implant apparatus
Inventor: CAPOTE MARCO D
IPC: A61B17/70
Filed: 2006-05-01
Abstract: Apparatuses are disclosed for use in orthopedic surgery, for example for procedures in which a support member is connected to the spine. A connector member (22) for connecting to an orthopedic implant (28) and a support member (30) is provided. A sleeve (24) fits around the implant, and a locking member (26) or mechanism connects to the sleeve. Locking causes a part of the sleeve to press the support against the connector, and causes a part of the sleeve to compress around the implant, so that the implant and support are substantially inhibited or prevented from moving with respect to each other.