baber/WOPTO huggingface dataset:
Patent BR-112020003601-B1 (BR)
Title: Anticorpo, polinucleotídeo, vetor, células hospedeiras, método para fabricar um anticorpo, composição farmacêutica, combinação farmacêutica e usos de um anticorpo, de uma combinação farmacêutica e de uma composição farmacêutica
Inventor: DU FANGYONG
IPC: C07K16/28
Filed: 2018-08-21
Abstract: a presente divulgação fornece anticorpos que se ligam ao cd137 humano ou a fragmentos de ligação ao antígeno destes, ácido nucleico que codifica os mesmos, composições terapêuticas destes e seu uso para potencializar a função das células t para regular positivamente as respostas imunes mediadas por células e para o tratamento de células t disfuncionais distúrbios, como imunidade a tumores, e para o tratamento de câncer.
Patent BR-112020008344-B1 (BR)
Title: Válvula e sistema de injeção química para uso em um poço subterrâneo
Inventor: BRIAN M STERNAMAN
IPC: E21B37/06
Filed: 2018-10-23
Abstract: uma válvula de injeção química pode incluir uma haste de válvula disposta reciprocamente em relação a uma vedação primária, e um restritor de fluxo variável a montante da vedação primária em relação a uma direção do fluxo através da válvula de injeção química. o restritor de fluxo variável restringe o fluxo quando a haste de válvula é desengatada da vedação primária. um sistema de injeção química pode incluir um tratamento químico bombeado através de uma válvula de injeção química e para o interior de uma coluna tubular em um poço, a válvula de injeção química incluindo uma haste de válvula, uma vedação primária engatada de forma vedada com a haste de válvula em uma posição fechada e desengatado da haste de válvula em uma posição aberta, e um restritor de fluxo que restringe o fluxo do tratamento químico a jusante da vedação primária na posição aberta.
Patent BR-112020010518-B1 (BR)
Title: Método para fazer uma composição de polietileno
Inventor: David m pearson
IPC: C08F210/16
Filed: 2018-12-13
Abstract: Um sistema de catalisador de zirconoceno-titanoceno compreendendo um catalisador de zirconoceno e um catalisador de titanoceno; poliolefinas; métodos de fazer e usar as mesmas; e artigos contendo as mesmas.
Patent BR-112020017373-B1 (BR)
Title: Dispositivo de comunicação sem fio, nó de rede de rádio, métodos de operação relacionados e meio legível por computador
Inventor: MATTIAS BERGSTRÖM
IPC: H04L5/00
Filed: 2019-02-26
Abstract: Métodos e aparelhos exemplares proveem o uso vantajoso de "primeiro" e "segundo" indicadores para controle de estado de célula em relação a um dispositivo de comunicação sem fio. Quando enviado individualmente, o primeiro indicador indica transições de estado ativado/desativado de acordo com a lógica de transição de estado sequencial correspondente implementada no dispositivo e o segundo indicador indica transições de estado ativado/inativo de acordo com a lógica de transição de estado sequencial correspondente implementada no dispositivo. Quando enviados em conjunto para uma certa célula servidora do dispositivo, o primeiro e segundo indicadores operam como um par combinacional que indica qual será o estado operacional da célula para o dispositivo, independentemente do estado atual da célula. Como exemplo, então, o "arranjo" anterior permite que a rede use a sinalização de bit único por célula para muitos cenários de controle de estado, incluindo o uso "normal" de indicadores de ativação/desativação legado, além de prover controle absoluto de estado através de dois bits por sinalização de célula que não depende do estado atual da célula.
Patent BR-112021005306-B1 (BR)
Title: Processo para aderir uma estrutura de espuma a um substrato de borracha
Inventor: HAIYANG YU
IPC: B32B37/10
Filed: 2018-09-20
Abstract: É fornecido um processo de aderir uma estrutura de espuma a um substrato de borracha. A estrutura da espuma é composta por uma primeira composição compreendendo um primeiro polímero à base de etileno tendo uma temperatura de fusão de pico TE1. Um filme composto por uma segunda composição compreendendo um segundo polímero à base de etileno tendo um índice de fusão = 10 g/10 min. e uma temperatura de fusão de pico TE2 é aplicada à superfície do substrato de borracha para formar uma configuração de substrato de borracha/filme. Uma força de compressão é aplicada a uma temperatura Tv (38°C = TE2 Tv) para formar um laminado de borracha vulcanizada/filme. A estrutura de espuma é aplicada a uma superfície do filme do laminado de borracha vulcanizada/filme para formar uma configuração de laminado de borracha vulcanizada-filme/espuma. Uma força de compressão é aplicada a uma temperatura TL, em que TE2 TL TE1, 15°C = (TE1 - TL) = 40°C e 10°C = (TL-TE2) = 70°C, para formar um vulcanizado laminado de filme de borracha/espuma.
Patent BR-112021016784-B1 (BR)
Title: Método e aparelho para preparação contínua de um material
Inventor: CHENG-SUNG HUANG
Filed: 2020-03-06
Abstract: MÉTODO E APARELHO PARA PREPARAÇÃO CONTÍNUA DE UM MATERIAL. Trata- se de um sistema (10) para preparar continuamente um material em pó seco. O sistema pode incluir um sistema (26) de suprimento de líquido, um sistema de fornecimento de material (10), um vaso (35), um filtro (41) e um agitador (45). O vaso pode receber um suprimento contínuo de líquido do sistema de suprimento de líquido e um suprimento contínuo de pó seco do sistema de fornecimento de material. O líquido e o material podem ser descarregados continuamente do vaso. Um filtro pode se estender de forma vedada através da saída para filtrar a solução que sai do vaso. O filtro pode incluir uma superfície a montante em contato com o volume interno do vaso. O agitador pode ser disposto dentro do vaso e pode ser configurado para agitar o conteúdo do vaso. O agitador pode incluir um membro (52) de limpeza configurado para contatar a superfície a montante do filtro enquanto agita o conteúdo.
Patent BR-122020020973-B1 (BR)
Title: Conjugado de anticorpo anti-her2-fármaco, uso do mesmo, fármacos antitumor e/ou anticâncer, e composição farmacêutica
Inventor: HIROYUKI NAITO
IPC: C07K16/28
Filed: 2015-01-28
Abstract: Como um fármaco antitumor tendo um excelente efeito antitumor e e segurança e também tendo um excelente efeito terapêutico, um conjugado de anticorpo-fármaco é fornecido, que é caracterizado pelo fato de que um composto antitumor representado pela fórmula (I) é ligado a um anticorpo anti-HER2 através de um ligante tendo uma estrutura representada pela fórmula: -L1-L2-LP-NH-(CH2)n1-La-(CH2)n2-C(=O)- (em que o anticorpo anti-HER2 é ligado no terminal de L1, e o composto antitumor é ligado a um grupo carbonila em uma porção -(CH2)n2-C(=O)- em que um átomo de nitrogênio em um grupo amino localizado na posição -1 no composto antitumor serve como uma parte de ligação).
Patent CS-205026-B2 (CS)
Title: Method of producing glocosamine derivatives
Inventor: BASCHANG GERHARD
IPC: C07K1/113
Filed: 1976-12-09
Abstract: Glucosamine derivatives of the formula <IMAGE> (X, R, R1, R2, R4, R6-R9 have the meaning stated in Claim 1) are prepared by condensation of corresponding 3-O-carboxymethylglucopyranosides with corresponding dipeptides. These glucosamine derivatives have the ability to increase the immunogenicity of an antigen on admixture therewith and, on systemic administration, to enhance the immunological reactivity of the treated organism. They can thus be used as adjuvants to increase the vaccine protection from bacterial, viral or parasitic pathogens.
Patent CS-274509-B2 (CS)
Title: Shifting device for conveyer and mechanized support
Inventor: PLEVAK LUBOMIR ING
IPC: E21D23/00
Filed: 1981-01-20
Abstract: The design deals with the problem of levelling out positions of the sole pieces of the mechanical support during their moving. The problem is solved by the moving device being provided with levelling mechanisms, i.e. with a front levelling mechanism (28), which is arranged on the pillar side and with a rear levelling mechanism (29), which is arranged on the filling side. The moving device (1) is placed either inside the section of a mechanical support, between its sole pieces (13), or between two adjacent sections. The front levelling mechanism (28) comprises front inclined surfaces (21), which are mounted on guide bars (12), and front inclined props (22), which are fastened to the sole pieces (13). The rear levelling control (29) comprises rear incline surfaces (23), which are connected to guide bars (12) and rear inclined props (24), which are fastened to the sole pieces (13).<IMAGE>
Patent CS-195296-B2 (CS)
Title: Method of making the powder-like carriers of catalysers from the silicic acid or catalyser from the palladium and silicic acid
Inventor: OHORODNIK ALEXANDER
IPC: C07C51/377
Filed: 1975-07-07
Abstract: 1503642 Catalytic reactions HOECHST AG 2 July 1975 [6 July 1974] 27838/75 Heading B1F In the process for carrying out heterogeneous catalytic reactions continuously in liquid phase as disclosed in specification 1363245. the catalyst is a palladium catalyst deposited on a silica carrier which is obtained by contacting a mixture of pulverulent silica carrier and in homogeneous silica particles with upward flowing water to free the carrier from the silica particles. The expression "inhomogeneous silica particles" is defined as meaning silica particles having a porosity which differs substantially from that of the other particles in the mixture. Such particles consist mainly of the fines present in the mixture. The silica carrier has a particle size of 20-300 microns and the catalyst may be produced by impregnating the carrier with a palladium salt which is subsequently reduced to metallic palladium in accordance with the process described in Specification 1403293.
Patent CS-208672-B2 (CS)
Title: Weaving machine with the aerating facility
Inventor: JASSNIKER KURT
IPC: D03J1/00
Filed: 1979-07-17
Abstract: Weaving machine having a ventilation system preparably for air conditioning, wherein some of the air passing through an air supply duct flows below the warp beam and cloth beam along the floor into the regions around the machine-i.e., more particularly into the operator gangways-and another component of the intaken air is guided inside the machine, more particularly towards the warp, to condition the warp yarns.
Patent CS-196445-B2 (CS)
Title: Method of producing novel derivatives of indolyl-acetic acid and salts of the same
Inventor: KIMURA MICHIO
IPC: C07D/
Filed: 1971-08-25
Abstract: 1336913 Indolylacetic acid derivatives SUMITOMO CHEMICAL CO Ltd 24 Aug 1971 [26 Aug 1970 27 Aug 1970 3 Oct 1970 9 Dec 1970 (3) 15 Feb 1971 16 Feb 1971] 39709/71 Heading C2C Novel compounds I and their salts in which X 1  and X 2  are O or CH 2 ; A is a saturated or unsaturated hydrocarbon chain of up to 5C optionally substituted by halo or phenyl; m is 0 or 1; n is 1 or 2; R 1  and R 2  are H or 1-4C alkyl; R 3  is 1-4C alkyl; 3-7C cycloalkyl; aryl optionally substituted by a hydrocarbon group, 1-4C alkoxy, 1-4C alkylthio, NO 2 , CN, CF 3 , -OCH 2 O-, -OCH 2 CH 2 O- or halo; a saturated or unsaturated mono- or polycyclio alicyclic group which may be substituted by halo, alkyl or phenyl or be condensed with a benzene ring; an alkyl group substituted by such an alicyclic group; or a heterocyclic ring with 5 or 6 ring members optionally substituted by CH 3 , C 2 H 5  or halo; and R 4  is H, 1-4C alkyl or a cation; are prepared by treating compounds II wherein B is 2H or a nitrogen protecting system with compounds III Compounds II may be prepared by treating compounds IV with compounds V, R 3 -(A) n -COhal. Compounds IV where B is other than 2H may be prepared by treating the appropriate compounds IV where B is 2H with a suitable protecting system. Pharmaceutical compositions having antiinflammatory, analgesic and antipyretic activities when administered orally comprise a compound I together with a suitable excipient.
Patent CS-247067-B2 (CS)
Inventor: KASHIWAYAMA SHINEI
IPC: A61K8/00
Filed: 1982-09-20
Abstract: Kosmetický prostředek obsahují jako hlavní
složku produkt kultivace nového kmene
Trichosporon Kashiwayama.
Patent CS-241034-B2 (CS)
Title: Tubes surface treatment equipment
Inventor: HACKSTEIN KARL G
IPC: C23G3/04
Filed: 1980-11-03
Abstract: Tubes, particularly of the type used in the nuclear field, are surface- treated e.g. pickled in an installation consisting of a tube feed, a transport unit, two treatment stations and a collecting tank, the transport unit comprising entry flaps (3), transport rollers (4) and guide ledges (5) for the tubes (2), one treatment station (25) being equipped with twin rollers (18) for guiding the tubes (2), with a collecting tank (9) for treatment medium connected to a hinged funnel (8) and with a take-up unit (6) for the tubes (2) consisting of an elastomeric plug provided with holes in a steel die with a force plunger provided with distributing bores, and the other treatment station (26) being provided with further twin rollers (18) for guiding the tubes (2), with sprinkler lances (10) for treating the inside of the tubes, with sprinkler collars (11) for treating the outer surface of the tubes and with one or more collecting tanks (13) for treatment medium. <IMAGE>
Patent JP-3145220-B2 (JP)
IPC: A61K31/185
Filed: 1993-01-07
Granted: 2001-03-12
Abstract: Pharmacologically active 1,2,4-triaminobenzene derivatives of the general formula <IMAGE> in which the symbols R1, R2, R3, R4, R5, Ar and Alk have the following meanings:     R1: hydrogen, C1-C6-alkyl, C2-C6-alkanoyl or the radical Ar;   R2: hydrogen or C1-C6-alkyl; R3: C1-C6-alkoxy, NH2, C1-C6-alkylamino, C1-C6- dialkylamino, amino which is substituted by the radical Ar, or C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, the radical Ar or the radical ArO-;   R4: hydrogen, C1-C6-alkyl or the radical Ar;   R5: hydrogen, C1-C6-alkyl or the radical Ar; Alk: a straight-chain or branched alkylene group with 1 - 9 C atoms, which can also be substituted by the radical Ar; Ar: phenyl radical which is substituted by the radicals R6, R7 and/or R8, where these radicals R6, R7 and R8 are identical or different and denote C1-C6-alkyl, C3-C7-cycloalkyl, hydroxyl, C1-C6-alkoxy, C2-C6-alkanoyloxy, halogen, hydroxyl, C1-C6-haloalkyl, -CN, -NH2, -NH-C1-C6-alkyl, -N(C1-C6-alkyl)2, -CO2H, -CO-C1 -C6-alkyl, -CO-O-C1-C6-alkyl, -COAr, -CO-OAr, -CONH2, -CONH-C1-C6-alkyl, -CON-(C1-C6-alkyl)2, -CONHAr, -NH-CO-C1-C6-alkyl, -NHCO-Ar, NHCO-C1-C6-alkoxy, -NH-CO-OAr, -NHCO-NH2, -NHCO-N(C1-C6-alkyl)2, -NHCO-NHAr, -NH-SO2-C1-C6-alkyl, -NH-SO2Ar, -NH-SO2-nitrophenyl, -SO2-OH, -SO2-C1-C6-alkyl, -SO2-Ar, -SO2-C1-C6-alkoxy, -SO2-OAr, -SO2-NH2, -SO2-NH-C1-C6-alkyl, -SO2-N(C1-C6-alkyl) 2, -SO2-NHAr, -SO2-C1-C6-alkoxy;   n: 0 or 1; and their pharmaceutically compatible acid addition salts.
Patent JP-2710324-B2 (JP)
IPC: C08F12/08
Filed: 1988-01-13
Granted: 1998-02-10
Abstract: Styrene-based polymer moldings with a crystallinity of at least 20% obtained by subjecting moldings of crystalline styrene-based polymers having mainly syndiotactic configuration to heat treatment at a temperature of 120 to 270 DEG C. These moldings are excellent in physical properties such as heat resistance and chemical resistance, and thus are expected to find various applications, for example, in general construction materials, electric or electronic devices, and car parts.
Patent AU-554031-B2 (AU)
Title: Separating unreacted material from crude silicon carbide
Inventor: ERSDAL HARALD
IPC: B03B9/04
Filed: 1983-02-04
Granted: 1986-08-07
Abstract: A process for purifying crude silicon carbide lumps from an Acheson furnace comprising agitating the lumps in a drum having a cylindrical wall, its axis substantially horizontal and having openings of controlled size, smaller than said crude lumps, in said cylindrical wall, separating the particles passing through said controlled size openings according to size and recirculating oversize particles back to said rotating drum and finally recovering product retained in said drum.
Patent AU-736014-B2 (AU)
Title: Vertebral implant
Inventor: SENEGAS JACQUES
IPC: A61B17/80
Filed: 1998-11-06
Granted: 2001-07-26
Abstract: A implant for a cervical vertebra comprises two branches adapted to extend respectively substantially along the two cervical laminae of a given cervical vertebra that have been spaced apart from each other after osteotomy of the laminae, and a rigid body interconnecting the two branches.
Patent AU-610134-B2 (AU)
Title: Use of metformin in the preparation of medicines
Inventor: WIERNSPERGER NICOLAS
IPC: A61K31/155
Filed: 1988-03-04
Granted: 1991-05-16
Abstract: The invention relates to the use of metformin and its salts in the preparation of medicaments. This derivative is used in the preparation of medicaments manifesting anti-ischaemic and antianoxic properties. It is also employed in the preparation of medicaments intended for the treatment or regression of neovascularisation.
Patent AU-594616-B2 (AU)
Title: Cement for cathode blocks
Inventor: CASTONGUAY LISE
IPC: C04B35/52
Filed: 1988-03-22
Granted: 1990-03-08
Abstract: The invention relates to a cement for the cathode blocks of electrolytic cells, e.g. Hall-Heroult cells used for the production of aluminum. The cement comprises a carbonaceous aggregate of particle size smaller than 48 Tyler mesh, a curable water-soluble liquid polymeric resin (preferably a phenol-formaldehyde resin), water and normally a curing agent for the resin. The water is used in such an amount that the proportion of the resin can be reduced without adversely affecting the viscosity of the cement at ambient temperature. The cement carbonizes when the cell is used and has a linear shrinkage of less than 5%, which reduces the tendency of the carbonized cement to crack during operation of the cell.
Patent AU-720399-B2 (AU)
Title: Activated linkers and methods for making and purifying the same
Inventor: IBRAHIM PRABHA N
IPC: A61K47/48
Filed: 1996-12-06
Granted: 2000-06-01
Abstract: The present invention relates to a process for purifying polyethylene glycols (PEGs) which utilizes hydrophobic interaction chromatography (HIC) to separate the PEGs based on their size and on their end-group functionality. The purified PEGs can be used to modify biologically active molecules and improve overall production of such molecules.
Patent AU-689531-B2 (AU)
Title: Process for producing S(+)-ibuprofen particles
Inventor: MOLLER TORSTEN
IPC: A61K47/32
Filed: 1995-01-26
Granted: 1998-04-02
Abstract: PCT No. PCT/AT95/00014 Sec. 371 Date Jul. 12, 1996 Sec. 102(e) Date Jul. 12, 1996 PCT Filed Jan. 26, 1995 PCT Pub. No. WO95/20382 PCT Pub. Date Aug. 3, 1995A process for the production of S(+)-ibuprofen-particles having improved flow properties comprises the steps that coarse-crystalline S(+)-ibuprofen is molten and then in a molten condition is finely distributed in a non-solving medium, preferably in cold water, and is chilled therein. This chilling results in a fine-crystalline primary structure that agglomerates to a secondary structure. In this agglomerate form the product is obtained which is filtered out and is dried. Such particles are suitable for direct pressing of tablets, optionally, tableting auxiliary substances being added, also for the production of tablets having a retarded release of the active substance.
Patent AU-747940-B2 (AU)
Title: Serpentine electrophoresis channel with self-correcting bends
Inventor: NORDMAN ERIC S
IPC: G01N30/38
Filed: 1998-11-12
Granted: 2002-05-30
Abstract: A serpentine electrophoresis channel, e.g., for a microchip format, is disclosed. The channel includes pairs of linear segments, e.g., parallel or right-angle segments, each joined by an angled channel region having a first curved channel portion subtending an angle alphaf>alpha, where alpha is the angle between segments in a pair, and a second curved channel portion subtending an angle alphas=alphaf-alpha. The angles and cross-sections of the two channel portions are such that deltatf, the time differential of analyte migration at inner and outer tracks in the first curved portion is equal to deltats, the time differential of analyte migration at outer and inner tracks in the second curved portion, respectively.
Patent AU-766305-B2 (AU)
Title: Compounds with growth hormone releasing properties
Inventor: ANKERSEN MICHAEL
IPC: A61P43/00
Filed: 1999-01-15
Granted: 2003-10-16
Abstract: Compounds of the general formula I <CHEM> and their use for treating medical disorders resulting from a deficiency in growth hormone.
Patent AU-763820-B2 (AU)
Title: Method of combustion or gasification in a circulating fluidized bed
Inventor: STAAB WERNER-FRIEDRICH
IPC: F23J15/06
Filed: 2000-01-19
Granted: 2003-07-31
Abstract: A material containing combustible components is burned or gasified in a circulating fluidized bed comprising a turbulence chamber, a solids separator connected to the upper area of the turbulence chamber, a return line leading from the solids separator to the turbulence chamber and a cooling device for the indirect cooling of solids arriving from the solids separator. The cooling device comprises several fluidized beds through which the solids pass one after the other. The first fluidized bed, into which the hot solids arriving from the solids separator are introduced first, is situated in a dechlorinating chamber. Fluidizing gas and at least one of the following dechlorinating additives: a) gaseous SO2 or a material which contains sulfur and releases SO2 in an oxidizing atmosphere, b) silicates and aluminium silicates, c) activated silicate, or d) other alkali-binding and HCl-releasing additives, are also introduced into the dechlorinating chamber in at least stoichiometric quantities so as to convert the alkali and metal chlorides contained in the arriving solids.
Patent AU-655658-B2 (AU)
Title: Laser beam scanning apparatus and method
Inventor: CONEMAC DONALD C
IPC: H04N1/047
Filed: 1992-06-05
Granted: 1995-01-05
Abstract: PCT No. PCT/US92/04734 Sec. 371 Date Feb. 2, 1994 Sec. 102(e) Date Feb. 2, 1994 PCT Filed Jun. 5, 1992 PCT Pub. No. WO92/22109 PCT Pub. Date Dec. 10, 1992A laser beam scanning apparatus employs a movable reflector (32) having a large number of flat reflective sides (44) a deflector (16) which shifts the laser beam (10) at high speed across a plurality of the reflective sides (44). The movement of reflector (32) is synchronized with the deflection of the laser beam (10) to produce a desired scan pattern in a first scan direction (X). The reflective sides (44) of the movable reflector (32) may be angled relative to each other in a second direction (Y) to produce different scan lines thereby providing an X-Y scan pattern. The combined high speed beam deflection and motion of the reflector (32) provide scanning of the beam (10) in parallel scan segments thereby providing high scanning speed of the beam with a high degree of resolution.
Patent AU-565388-B2 (AU)
Title: Anthelmintic gel composition
Inventor: QUINLAN JAMES MICHAEL
IPC: A61K9/08
Filed: 1983-12-12
Granted: 1987-09-17
Abstract: This invention relates to aqueous gels, which remain gelatinous in a temperature range as low as -270 DEG C containing dl- or 1-6-phenyl-2,3,5,6-tetrahydro-(-)imidazo [2,1-b]thiazole, acylamino derivatives thereof and pharmaceutically acceptable salts thereof, characterized by gelation and preparation at ambient temperatures (20-60 DEG C), under vacuum, without additional heating or cooling in their preparation.
Patent AU-667825-B2 (AU)
Title: Biocidal proteins capable of isolation from brassicaceae, compostiae and leguminosae families
Inventor: BROEKAERT WILLEM FRANS
IPC: A01H1/00
Filed: 1992-08-27
Granted: 1996-04-18
Abstract: Biocidal proteins isolated from seeds have been characterized, in particular proteins isolated from members of the Brassicaceae, Compositae and Leguminosae families including Raphanus, Brassica, Sinapis, Arabidopsis, Dahlia, Cnicus, Lathyrus and Clitoria. The proteins show a wide range of antifungal activity and some are active against Gram-positive bacteria. All share a common amino acid sequence. DNA encoding the proteins has been isolated and incorporated into vectors. Plants transformed with this DNA may be produced. The proteins find commercial application as antifungal or antibacterial agents; transformed plants will show increased disease-resistance.