baber/WOPTO huggingface dataset:
Patent PT-1303631-E (PT)
Title: Biotransformation of biologically active compounds made of various classes of chemical substances by means of laccase and manganese peroxidase enzymes
Inventor: LINDEQUIST ULRIKE
IPC: A61P31/04
Filed: 2001-06-23
Abstract: A process for the preparation of biologically active compounds, wherein active substances having additional functional groups and a modified spectrum of activity and modified application properties are obtainable from medicinal substances and plant protective agents as substrates which bear at least one amino or hydroxy functional group by using a one-electron reaction catalyzed by enzymes or compositions having enzymatic activity and a broad spectrum of substrates, characterized in that free-radical forming enzymes are employed as enzymes and/or supernatants of ligninolytic fungi in solution are employed as compositions having enzymatic activity, wherein the following can be introduced as additional functional groups: A) polyfunctional synthones which provide the active substance with an altered dissolving behavior in aqueous and lipophilic systems and a high interfacial activity; B) aromatic molecules, heteroaromatic compounds; C) heterocyclic compounds; D) active substances having an independent biological activity; E) active substances combining an independent activity and surfactant properties in one molecule; which yield coupling products being covalently linked with the starting materials and having an altered partition behavior which enable polyfunctional interactions with the target organism.
Patent PT-1332199-E (PT)
Title: Products produced from rapid thermal processing of heavy hydrocarbon feedstocks
Inventor: FREEL BARRY
IPC: C10G9/00
Filed: 2001-09-18
Abstract: A method of producing a vacuum gas oil (VGO), consisting of: 
(I) upgrading bitumen by a method comprising: 
(i) providing a particulate heat carrier into an upflow reactor; 
(ii) introducing bitumen into the upflow reactor at at least one location above that of the particulate heat carrier so that a loading ratio of the particulate heat carrier to bitumen is from about 10:1 to about 200:1, wherein the upflow reactor is run at a temperature of from about 300°C to about 700°C; 
(iii) allowing bitumen to interact with the heat carrier with a residence time of less than about 5 seconds, to produce a product stream; 
(iv) separating the product stream from the particulate heat carrier; 
(v) regenerating the particulate heat carrier; and 
(vi)collecting a gaseous and liquid product from the product stream, and  
(II) isolating the VGO from the liquid product.
Patent PT-1216670-E (PT)
Inventor: SABOLICH JOHN A
IPC: A61F2/78
Filed: 1997-04-23
Abstract: An improved above-the-knee prosthesis with an anatomically configured socket is characterized by one or more contours which correspond to a pre-selected anatomical contour of the upper or lower residual thigh. By exaggerating the depth of the contour in the socket as compared with the corresponding contour in the thigh, the socket grips the residual thigh and maintains the femur in proper alignment. The new channels and contours allow the patient using the socket to have improved rotational support and control over the prosthesis by providing structures which the muscles of the upper and lower residual thigh can "grip." The socket snugly contains the thigh and maintains it, throughout the gait cycle, in a proper anatomical position. This fit increases the comfort of the prosthesis and minimizes gait abnormalities common with other artificial limbs. The increased support helps maintain the physical condition of the residual limb. The extended and new channels allow the muscles of the patient's residual thigh to flex and contract against and around the channels, thereby reducing muscle atrophy. <IMAGE>
Patent PT-1243278-E (PT)
Title: Use of blood having an increased concentration of nitric oxide for the manufacture of a medicament
Inventor: BOLTON ANTHONY ERNEST
IPC: A61K35/14
Filed: 1993-02-08
Abstract: A method of increasing the nitric oxide concentration in the blood which comprises contacting blood with a nitric oxide concentration-increasing effective amount of ozone gas and ultraviolet radiation. Blood prepared by the method of the invention is used for treating a variety of conditions benefited by increased blood levels of nitric oxide.
Patent PT-1306626-E (PT)
Inventor: VERGARA JOSE M
IPC: F24H1/14
Filed: 2002-10-17
Abstract: The invention relates to an equipment to be used in a gas-fired water heater which equipment contains a combustion chamber (2) and a heat exchanger (1). Accordingly the combustion chamber (2) is made of a ceramic material and provided with slots (3) for crossing the heating elements (4) of the heat exchanger (1) through the opposite walls (5,6) of the combustion chamber (2). <IMAGE>
Patent PT-1435205-E (PT)
Title: Process for the production of a modified starch
Inventor: KOSSMANN JENS
IPC: A23L5/10
Filed: 1996-09-19
Abstract: New nucleic acid (I) encoding a protein (P), present in plant cells in both soluble form and bound to starch granules, (a) encodes a 1464 amino acid (aa) of (P) reproduced in the specification; (b) includes the coding region of a 4856 bp sequence reproduced in the specification; (c) can hybridise with (a) or (b); (d) is degenerate, within the genetic code, with (a)-(c) or (e) is a fragment, deriv. or allelic variant of (a)-(d). Also claimed are: (1) DNA (II) encoding RNA that is antisense to a (I) transcript, has ribozyme activity on this transcript or which when expressed in a plant cell reduces expression of (I) by a co-suppressant effect; (2) nucleic acid fragments (III) of at least 15 nucleotides that hybridise specifically with (I); (3) plants contg. cells contg. (I) or (II); and (4) starch obtained from these plants.
Patent PT-1684792-E (PT)
Title: Pharmaceutical formulations for the sustained release of interleukins and therapeutic applications thereof
Inventor: MEYRUEIX REMI
IPC: A61K47/48
Filed: 2004-11-19
Abstract: A liquid pharmaceutical formulation (I) for prolonged release of interleukin(s) (IL) comprises a low viscosity aqueous colloidal suspension of submicron particles of water-soluble, biodegradable polymers (II) carrying hydrophobic groups, non-covalently associated with IL(s) and optionally other active agent(s), where on parenteral injection (I) forms a gelled depot for prolonging the duration of active agent release to more than 24 hours. A liquid pharmaceutical formulation (I) for prolonged release of interleukin(s) (IL) comprises a low viscosity aqueous colloidal suspension (with water as dispersion medium) based on submicron particles (SMP's) of water-soluble, biodegradable polymers (II) carrying hydrophobic groups (HG's), non-covalently associated with IL(s) and optionally other active agent(s). On parenteral injection, (I) forms a gelled depot in vivo (at least partially due to physiological proteins), controlling and prolonging the duration of active agent release to more than 24 hours. (I) is liquid under the injection conditions; at physiological temperature and/or pH; and/or in presence of physiological electrolytes at physiological concentrations and/or surfactant(s). Independent claims are included for: (1) a variant of (I) as described above, where the duration of release of active agents is not restricted but the concentration of (II) is sufficiently high to form a gelled depot in vivo in presence of protein(s) after parenteral injection; (2) novel derived products (preferably in powder or gel form), consisting of SMP's formed by non-covalent association of (II) and active agents as above and obtained from (I); and (3) methods of preparation of (I). ACTIVITY : Antiinflammatory; immunomodulator. MECHANISM OF ACTION : T-Lymphocyte activator; T-lymphocyte proliferation profieration inducer.
Patent PT-1790896-E (PT)
Title: Press fitting for a pipe
Inventor: DANKBAR BERNHARD
IPC: F16L33/207
Filed: 2006-11-23
Abstract: The fitting has a fitting body (12) with a supporting body (16), and a crimp sleeve (30) with a crimping area (66), where a crimping indication ring (52) is provided at the sleeve. The ring has a number of ring segments (68, 70, 72), where the adjacent ring segments are connected one below the other by a destructible connection bar (64) that is separable from the segments. The ring is arranged in the sleeve in such a manner that the segments are provided outside the crimping area, where the bar and a lever unit are extended up to the crimping area. An independent claim is also included for a method of pressing a press-fitting.
Patent PT-1860242-E (PT)
Title: Permanent cylindrical road sign for vertical signalling
Inventor: LESAGA FRANCISCO JAVIER ALDAY
IPC: E01F9/627
Filed: 2006-12-29
Abstract: A permanent cylindrical deformable road sign for vertical signalling, comprising a base (1) anchorable to the ground and a vertical body (2) made of flexible plastic that can be fastened to said base (1), so that bayonet reciprocal coupling means are formed in the base (1) and the vertical body (2), said coupling means operating in conjunction with an anti-turn locker (3) adequate to be placed between the base (1) and the vertical body (2) when the latter is fastened to the former. The anti-turn locker (3) is releasable from its blocking position with an anti-theft key (6) and is provided with an elastic arm (3.1) that, when the rotation movement for coupling the vertical body (2) and the base (1) is completed, is able to reach a position in which it is rigidly interposed in the path of the rotation movement for removing the vertical body (2) from the base (1).
Patent PT-1888004-E (PT)
Title: Dressing material and method for its production
Inventor: LANGEN GUENTER
IPC: A61F13/04
Filed: 2006-05-18
Abstract: The invention relates to a dressing material comprising a thermoplastic, the thermoplastic being applied to a first textile web and the thermoplastic containing a first microencapsulated dye. Furthermore, the invention comprises a production method and a bandage, an orthopedic support dressing and an application.
Patent PT-1896160-E (PT)
Title: Method and apparatus for energy reduction in acid gas capture processes
Inventor: SVENDSEN HALLVARD F
IPC: B01D/
Filed: 2006-06-28
Abstract: The invention relates to a new method for removing and recovering of acid gases from a gaseous mixture in an absorption plant by adding an organic acid to a stream of the rich absorbent in the desorber in order to release acid gas by shifting the acid gas equilibrium towards the gas side, and the organic acid is subsequently separated from the absorbent. With this method, the energy consumption of the process is substantially reduced. The invention also relates to an apparatus for performing this method.
Patent PT-1962656-E (PT)
Title: Container provided with a microwave heatable element
Inventor: JOUILLAT JEAN-FRANCOIS
IPC: A47J36/00
Filed: 2006-11-28
Abstract: The invention relates to a container (1,11,18,27) having a body and a closure for an opening in the body, which body comprises a heatable content (5,19) and, in heat exchange contact, a microwave heatable element (6,14,22,28).
Patent PT-1960418-E (PT)
Title: Process for the purification of vancomycin
Inventor: TOMMASO VINCENZO DE
IPC: C07K1/34
Filed: 2006-12-07
Abstract: The present invention concerns a process for the purification of macrolide antibiotics. More specifically it concerns a process for the purification of macrolide antibiotics that result in a white powder. The powder remains white also after some time of storage.  The process of the present invention is performed by dissolving the macrolide antibiotics, e.g. commercial vancomycin hydrochloride, in water and subjecting the solution to ultrafiltration with a membrane having nominal retention lower than 30,000 Da, preferably of 10,000 Da. The purified solution is preferably concentrated by reversed osmosis and then lyophilized at the optimized conditions of pressure and temperature to obtain a white powder.
Patent PT-1844866-E (PT)
Title: Lift dipping plant
Inventor: SPORER ROBERT
IPC: B01J19/18
Filed: 2007-03-30
Abstract: Raising and lowering unit especially for cleaning of workpieces including at least two chambers containing cleaning liquid forming an immersion bath.The unit has a lifting table and a cage for the workieces which can be raised and lowered with the workpieces.
Patent PT-754176-E (PT)
Inventor: ZELLE ROBERT EDWARD
IPC: A61K31/445
Filed: 1995-03-23
Abstract: The present invention relates to compounds as represented by formula (I) that can maintain, increase, or restore sensitivity of cells to therapeutic or prophylactic agents. This invention also comprises pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly well-suited for treatment of multi-drug resistant cells, for prevention of multi-drug resistance and for use in multi-drug resistant cancer therapy.
Patent PT-833640-E (PT)
Inventor: FLOYD ALISON
IPC: A61K31/53
Filed: 1996-06-20
Abstract: PCT No. PCT/EP96/02759 Sec. 371 Date Dec. 9, 1997 Sec. 102(e) Date Dec. 9, 1997 PCT Filed Jun. 20, 1996 PCT Pub. No. WO97/00681 PCT Pub. Date Jan. 9, 1997A lyophilized formulation of lamotrigine having been prepared by lyophilizing a frozen sterile aqueous solution of Imotrigine mesylate in which the pH is from 2.4 to 4.
Patent PT-865435-E (PT)
Inventor: PHILIPS RICHARD E
IPC: C07D253/06
Filed: 1996-11-21
Abstract: Process of producing 3-amino-1,2,4-benzotriazine 1,4-dioxide by reacting benzofurazan-1 oxide with disodiumcyanamide under homogeneous conditions followed by allowing crystallization to occur in a buffered solution. In a preferred embodiment, the process comprises reacting benzofurazan-1 oxide with cyanamide and sodium hydroxide under homogeneous conditions followed by purification in a mixture of acetone and acetic acid.
Patent PT-843026-E (PT)
Inventor: KANG DAVID
IPC: C25D5/02
Filed: 1997-10-14
Abstract: A process is provided for plating a coating onto a gas turbine engine component without detrimentally effecting air flow through cooling holes by injecting a maskant into the cooling passage to fill the cooling holes with the maskant, plating the external surface of the component with a coating, then removing the maskant from the component. <IMAGE>
Patent PT-932399-E (PT)
Inventor: LI CHUN
IPC: A61K33/24
Filed: 1997-03-11
Abstract: Disclosed are water soluble compositions of paclitaxel and docetaxel formed by conjugating the paclitaxel or docetaxel to a water soluble chelator, polyethylene glycol or polymer such as poly (1-glutamic acid) or poly (1-aspartic acid). Also disclosed are methods of using the compositions for treatment of tumors, autoimmune disorders such as rheumatoid arthritis and for prediction of paclitaxel uptake by tumors and radiolabeled DTPA-paclitaxel tumor imaging. Other embodiments include the coating of implantable stents for prevention of restenosis.
Patent PT-970924-E (PT)
Inventor: SELCI GIANCARLO
IPC: C03B33/10
Filed: 1998-11-06
Abstract: There is described an apparatus for cutting glass plates comprising a tool holder head (8) movable along three axes (X, Y, Z) orthogonal to each other and provided with a tool magazine (28) for quick tool change, as well as preferably provided with a further magazine including at least one auxiliary head for carrying out special operations. <IMAGE>
Patent PT-1027669-E (PT)
Inventor: VINGRON MARTIN
IPC: G16B50/30
Filed: 1998-08-14
Abstract: In order to cluster sequences to biological groups, the conventional databank search programs are iteratively called in with a view to clustering various related sequences to one determined protein sequence. The inventive method enables full automatic distribution of a high number of protein sequences in groups. The major part of such groups are segregated, so that they represent a meaningful and valid grouping of data.
Patent PT-1140898-E (PT)
Inventor: BARTOSZYK GERD
IPC: A61P25/20
Filed: 1998-12-22
Abstract: Amide and urea derivatives of the formula Iin which R1, n, Y, q, Z, r and R2 have the meanings indicated in Claim 1, are potent 5-HT1B/1D antagonists and exhibit 5-HT reuptake-inhibiting actions and are suitable for the treatment and prophylaxis of anxiety states, depressions, schizophrenia, compulsive ideas, tardive dyskinesias, learning disorders, age-dependent memory disorders, for positively affecting obsessive-compulsive behaviour (OCD), and also for the treatment and for the control of the sequelae of cerebral infarcts such as stroke and cerebral ischaemias.
Patent PT-1005083-E (PT)
Inventor: MERMET-GUYENNET MICHEL
IPC: H01L23/473
Filed: 1999-11-22
Abstract: Power electronic component (28) comprises a first composite structure (19) for thermal transfer and electric insulation, comprising two conducting or semiconducting layers (18) onto which is mounted at least one power semiconducting circuit (20) with contacts (23) connected to an array of conducting elements insulated from each other, this array being integrated into a second composite structure (119) for thermal transfer and electric insulation made of at least one semiconductor layer (110). One of the first and second composite structures comprises internal passages (12,112) for heat exchanging fluid.
Patent PT-1129129-E (PT)
Inventor: KILNER IAN
IPC: C08J11/00
Filed: 1999-09-15
Abstract: The present invention provides a process for recycling fines produced during the production of powder coatings comprising the steps of heating the fines for a sufficient time and a sufficient temperature such that a reusable product is obtained, cooling such product, crushing the cooled product to produce particles of a desired particle size, and removing any particles which are not of desired particle size.
Patent PT-1117963-E (PT)
Inventor: ROFFELSEN FRANCISCUS
IPC: F24D3/10
Filed: 1999-09-29
Abstract: Method and apparatus for operating a closed hot water installation provided with a pipe system, a boiler, heat exchangers, an expansion tank, a water make-up provision and a de-aerator, the method including the steps of opening a non-return valve to allow air to escape, detecting a water level in the de-aerator, feeding water to the closed installation when the level falls below a predetermined level, blocking opening of the non-return valve until the water level has fallen to a first level and starting the feed of water when a second lower level is reached.
Patent PT-1137420-E (PT)
Title: Use of a combination of a purine and a nitrogen monoxide donor for preventing or treating sexual dysfunction
Inventor: GORNY PHILIPPE
IPC: A61K33/00
Filed: 1999-12-02
Abstract: Abstract of Disclosure A method for using, in combination, a purine and a nitric oxide donor as active ingredients in the preparation of a drug for preventing or treating disorders of physiological and/or anatomical response to sexual stimulation in human beings.
Patent PT-1139871-E (PT)
Title: Device and method for measuring the periphery of a body
Inventor: OSER DANIEL
IPC: A61B5/103
Filed: 1999-11-24
Abstract: The present invention relates to an apparatus and a method for determining the circumference of a body. In this case, the apparatus has at least the following elements: a wire which has a known length section of length LD, a position sensor (4), which is in operative contact with the wire (5) such that it outputs a signal S, as soon as the wire (5) exerts at least a predetermined tensile force Z on the position sensor (4), a drive device (6, 7) for tensioning the length section of the length LD of the wire along the circumference (2) of the body (3), the drive device (6, 7) being connected to the position sensor (4) such that when the signal S is output, the wire (5) is no longer tensioned, and a distance meter (10), in operative contact with the drive device (6, 7), for measuring the distance WD traced by the wire (5) as it is tensioned along the circumference (2) of the body (3) by the drive device (6, 7), so that the circumference (2) of the body (3) can be determined from the length LD, the distance WD and an apparatus-dependent geometry factor G. In addition, the invention relates to the use of the apparatus according to the invention and the method according to the invention for plethysmography, in particular for determining the circumference of extremities.
Patent SG-8786-G (SG)
Title: Polypeptides, process for their production, pharmaceutical compositions comprising said polypeptides and their use
IPC: A61K38/22
Filed: 1986-01-31
Abstract: Straight-chain and mono-cyclic polypeptides containing the basic sequence  <IMAGE>  wherein X is an amino acid residue, the residues in the 1- and 6-positions being linked by an -S-S- bridge when the polypeptide is monocyclic, have pharmacological, in particular GH-, gastric- and pancreatic-secretion inhibiting activity.
Patent IE-780974-L (IE)
Title: Vaccine for immunotherapy of neoplastic disease
IPC: A61K39/00
Filed: 1978-05-15
Abstract: A process for producing a vaccine for use in the immunotherapy of neoplastic disease, said vaccine being produced by: (a) obtaining an amount of cancerous tissue from the patient to be treated and suspending said tissue in an aqueous solution of between about 100 and 150 millimolar sodium chloride and between about 5 and 15 millimolar sodium EDTA, (b) disaggregating the tissue into its component cells; (c) suspending the cells in water: (d) subjecting the suspended cells to hydrodynamic turbulence sufficient to disrupt the cells and detach therefrom the cell components possessing cancer-specific antigens; and (e) contacting and admixing the cell components obtained in step (d) with a source of manganousion to form the vaccine. [IN149012A1]
Patent FI-803504-L (FI)
Inventor: GOUGH PATRICIA MARIE
IPC: A61K39/225
Filed: 1980-11-10
Abstract: A vaccine for protecting swine against transmissible gastroenteritis (TGE) is prepared from a specific antigenic protein (SPA) obtained by separation from TGE virus. The SPA is characterized by the buoyant density of 1.02 to 1.03 gm/ml in a solution of sucrose and an Rf value of approximately 1.84 relative to human serum albumin. The vaccine may be prepared in parenteral dose form for administration to pregnant sows, thereby effectively protecting the baby pigs against fatal TGE infection.
Patent FI-830703-L (FI)
Inventor: DRUSCHKE WOLFGANG
IPC: C08F220/20
Filed: 1983-03-02
Abstract: 1. A process for the production of self-adhesive coatings by applying acrylates to a base and exposing the coating to high-energy radiation, wherein derivatives of dihydroxypropyl acrylates are employed as the acrylates, these are mixed with (a) from 0 to 120% by weight of polymers having a glass temperature below 0 degrees C and a K value of from 10 to 80, and/or (b) from 0 to 90% by weight of a conventional tackifying resin, and the mixture is applied to the base, the amount of (a) and (b) together being not less than 5% by weight and the percentages of (a) and (b) being based on the weight of the dihydroxypropyl acrylates derivatives.
Patent IE-34637-L (IE)
Title: Substituted ureas; weed killers
IPC: C07C275/28
Filed: 1970-08-11
Abstract: 1301728 Cycloalkylphenyl substituted ureas PHILIPS GLOEILAMPENFABRIEKEN NV 10 Aug 1970 [13 Aug 1969] 38387/70 Heading C2C [Also in Divisions A5 and C4] Cycloalkylphenyl substituted ureas of the general formula in which A is a cycloalkyl group containing 3 or 4 carbon atoms, Hal is a halogen atom, Alk is an alkyl group containing from 1 to 4 carbon atoms, n = 0 or 1 and m = 0 or 1, are prepared by reacting a compound of with a compound of in the presence of an acid binder or a compound of the formula with a compound of the formula Compounds claimed per se are 3-(4-cyclopropylphenyl)-1,1-dimethyl urea; 3-(4-cyclopropylphenyl) - 1,1 - diethyl urea; 3 - (4 - cyclopropylphenyl) - 1 - methoxy - 1 - methyl urea; 3 - (3 - cyclopropylphenyl) - 1,1 - dimethyl urea; 3 - (2 - chloro - 3 - cyclopropylphenyl)- 1,1-dimethyl urea. The compounds have herbicidal properties.
[GB1301728A]