baber/WOPTO huggingface dataset:
Patent NZ-210626-A (NZ)
Title: Multi-stage contraceptive combination
Inventor: LACHNIT-FIXSON URSULA
IPC: A61K31/565
Filed: 1984-12-19
Abstract: A multistage combination preparation is useful for oral contraception and comprises a surprisingly low amount of gestodene as the gestagen and comprises ethinylestradiol as the estrogen.
Patent NZ-214895-A (NZ)
Title: Method of preparing liposomes; pack; and composition
Inventor: MCGURK J G
IPC: A61K9/50
Filed: 1986-01-22
Abstract: The invention provides a method for the preparation of liposomes by preparing a solution of a lipid component in an organic solvent and initially combining the thus-formed solution with a second component comprising water to form a reservoir of combined material which affords a multiple-dose system. Then a portion of an intimate mixture formed from the combination can be passed under pressure through an orifice to produce an aerosol spray containing liposomes. Generally an active material which is biologically-active and/or useful in the treatment or care of the human or animal body or of plants may be included in the combination. Also provided by the invention is a pack comprising at least a first chamber containing said combination. The first chamber and/or a second chamber includes at least one propellant material, and the pack includes an arrangement for dispensing the combination through an orifice. In a modification the pack comprises at least a first chamber containing a solution of a lipid component in an organic solvent and means to supply an aqueous component to the chamber. In addition, the invention provides a composition for use in preparing a plurality of unit doses comprising liposomes based on a mixture of said lipid and aqueous components.
Patent NZ-216613-A (NZ)
Title: 7-fluoro prostacyclins and compositions
Inventor: HOLLAND G W
IPC: A61K31/34
Filed: 1986-06-20
Abstract: Compounds of the formula 
<CHEM>
 wherein R is hydrogen or lower alkyl, R2 is hydrogen, methyl or fluoro; and R2 min  is fluoro or trifluoromethyl; with the proviso that when R2 min  is trifluoromethyl, R2 is hydrogen or methyl; pharmaceutically acceptable salts, optical antipodes and racemates thereof are useful as blood platelet anti-aggregating agents.
Patent NZ-228458-A (NZ)
Title: Chimeric gene useful for endowing plants with resistance to 3,5-dihalo-4-hydroxy-benzonitrile herbicides
Inventor: LEROUX BERNARD
IPC: C12N15/62
Filed: 1989-03-22
Abstract: New chimeric gene (I) confers resistance to herbicides (II) of the 3,5-dihalo-4-hydroxybenzonitrile type comprises: (i) at least one gene (Ia) encoding resistance to (II); (ii) a heterologous promoter; and optionally(iii) a polyadenylation signal. The promoter is from a gene naturally expressed in plant cells: (a) the 35S RNA promoter of cauliflower mosaic virus (P1); or (b) the promoter from the small subunit of the ribulose-1,5-bis-phosphatocarboxylase oxidase (Rubisco) gene of Helianthus annuus (P2). Also claimed are: (1) vectors used to transform plants to make them resistant to (II); (2) microorganisms comprising (I); (3) plant cells comprising (Ia); (4) transformed plants (or plant parts) obtained by regenerating (3); (5) seeds of (4); and (6) a process of selectively weeding using (II) applied to (4).
Patent NZ-238571-A (NZ)
Title: N-benzyl-n'-phenyl and -phenalkyl thioureas and pharmaceutical compositions thereof
Inventor: WALPOLE CHRISTOPHER SIMON JOHN
IPC: A61K31/195
Filed: 1991-06-17
Abstract: Compounds of formula II <CHEM> wherein one of R1 and R2 is branched lower alkyl and the other is hydrogen or branched lower alkyl, R3 is hydrogen or C1-4alkyl, R4 and R5 are hydrogen, halogen, C1-5alkyl, substituted C1-5alkyl, aryl, substituted or unsubstituted aryl or a group of formula, -COOH, -COOR8 or -CONR9R10, wherein R8 is C1-5alkyl and R9 and R10 are, independently, hydrogen or C1-5alkyl, R6 and R7 have the meanings given for R4 and R5 or, together with the carbon atom to which they are attached, form a substituted or unsubstituted C3-7cyclo-alkyl group, R is -O-, -S- or -NH- and X is -(CH2)n- wherein n is zero, 1, 2 or 3, and their physiologically hydrolysable and acceptable esters and amides and pharmaceutically acceptable salts thereof, processes for their production and pharmaceutical compositions comprising them.
Patent NZ-243178-A (NZ)
Title: Laundry detergent containing nonionic surfactant system comprising polyhydroxy fatty acid amide and one or more additional nonionic surfactants
Inventor: BAILLELY GERARD MARCEL
IPC: C11D1/52
Filed: 1992-06-17
Abstract: The present invention provides laundry detergent compositions comprising one or more water soluble anionic, cationic, ampholytic or zwitterionic detersive surfactants or mixtures thereof and a combination of (a) at least 1 % by weight of the composition of a polyhydroxy fatty acid amide having formula (I), wherein R1 is H, a C1-C4 hydrocarbyl, 2-hydroxy ethyl, 2 hydroxy propyl, or mixtures thereof, R<2> is a C5-C31 hydrocarbyl, and Z is a polyhydroxyhydrocarbyl having a linear hydrocarbyl chain with at least 3 hydroxyl groups directly connected to the chain, or an alkoxylated derivative thereof; and (b) at least 1 % by weight of the composition of a substantially water-insoluble ethoxylated C11-C15 primary aliphatic alcohol containing an average of no more than five ethylene oxide groups per mole and having an ethylene oxide content of less than 50 % by weight. Preferred water soluble surfactants are anionic surfactants and more preferred compositions are free of alkyl benzene sulfonate surfactants.
Patent NZ-254272-A (NZ)
Title: Paper colouring apparatus; details regarding roller train for conveying ink from a reservoir to the inker roll
Inventor: RANNESTAD PER-GUNNAR
IPC: B05C1/08
Filed: 1993-07-06
Abstract: The invention relates to a paper coloring apparatus for especially water colors or water-based inks, wherein a driven running paper web is positioned around a turning roller constituting the counter pressure roller for an inker and, together with the latter, are included in a roller train adapted to convey ink from a reservoir to the inker. One has aimed at transferring ink to the paper in so small amounts that after-drying of the paper becomes unnecessary. According to the invention, the roller train is adapted to be driven by means of the running paper web and comprises five or more rollers.
Patent NZ-260848-A (NZ)
Title: High foaming liquid detergent comprising as nonionic surfactant an alkyl or fatty acid sorbitan ether with an ethylene oxide condensate, or an alkylphenolether of an ethylene oxide/propylene oxide condensate, a betaine and an ethoxylated alkyl ether sulphate
Inventor: ERILLI RITA
IPC: C11D1/74
Filed: 1994-06-24
Abstract: A high foaming, light duty liquid detergent with desirable cleansing properties and mildness to the human skin comprising: a water soluble nonionic surfactant; a water soluble or dispersible foaming, anionic surfactant; a zwitterionic betaine surfactant.
Patent NZ-263669-A (NZ)
Title: Preparation of 3-ethyl- (and prop-2-yl-)amino-2-piperazinyl pyridine and pentahydrate clathrates thereof
Inventor: PEARLMAN BRUCE ALLEN
IPC: C07D213/74
Filed: 1994-03-15
Abstract: The invention is a process to produce 3-alkylamino-2-piperazinylpyridines (III), <CHEM> where R3 is -CH2-CH3 or -CH(CH3)2, and a process to purify them. The 3-alkylamino-2-piperazinylpyridines (III) are used in the production of known compounds useful for treating individuals who are HIV positive.
Patent NZ-267337-A (NZ)
Title: Indolocarbazole derivatives and pharmaceutical compositions thereof
Inventor: DIONNE CRAIG A
IPC: C07D487/14
Filed: 1994-05-27
Abstract: The use of a therapeutic amount of an indolocarbazole compound K-252a, or a preferred derivative thereof, to treat a pathological condition of the prostate gland in a male mammal. The condition being one that results from an excessive proliferation of prostate cells. Certain functional derivatives of K-252 can be used to prevent prostate tissue growth, and thereby to attenuate or cause regression of conditions exhibited by pathological proliferation of prostate cells, for example, benign prostatic hypertrophy, or prostatic cancer. A functional derivative of K-252a is a derivative that inhibits the tyrosine kinase activity associated with a neurotrophin receptor, for example, trkA, trkB or trkC
Patent NZ-280674-A (NZ)
Title: Promoter of beta2-subunit of neuronal nicotinic acetylcholine receptor, transgenic animals
Inventor: CHANGEUX JEAN-PIERRE
IPC: C12N15/85
Filed: 1995-12-14
Abstract: Several genes encoding subunits of the neuronal nicotinic acetylcholine receptors have been cloned and regulatory elements involved in the transcription of the  alpha :2 and  alpha :7-subunit genes have been described. Yet, the detailed mechanisms governing the neuron-specific transcription and the spatio-temporal expression pattern of these genes remain largely uninvestigated. The  beta 2-subunit is the most widely expressed neuronal nicotinic receptors subunit in the nervous system. We have studied the structural and regulatory properties of the 5' sequence of this gene. A fragment of 1163 bp of upstream sequence is sufficient to drive the cell-specific transcription of a reporter gene in both transient transfection assays and in transgenic mice. Deletion analysis and site-directed mutagenesis of this promoter reveal two negative and one positive element. The positively acting sequence includes one functional E-box. One of the repressor elements is located in the transcribed region and is the NRSE/RE1 sequence already described in promoters of neuronal genes.
Patent NZ-331388-A (NZ)
Title: Incorporating drug into polymeric material as solid articles of up to 10 microns cross-section, the drug particles comprising up to 70 wt% of the composition
Inventor: EURY ROBERT P
IPC: A61F2/04
Filed: 1996-03-19
Abstract: his drug-loaded polymeric material containing a therapeutic drug can be applied to a structure of an intravascular stent.  A therapeutically effective amount of a therapeutic drug is incorporated into such a layer of polymeric material, without significantly increasing the thickness of the stent, to avoid interfering with the function of the stent.  The drug-loaded polymer coating of the stent can be formed to include pores, can be multi-layered to permit the combination of a plurality of different drug containing materials in a single stent, and can include a rate controlling membrane to allow for controlled retention and delivery of selected drugs within the affected blood vessel upon implantation.  The layer of polymeric material is manufactured by combining the selected polymeric material with a relatively high loading of the therapeutic drug in a thermal process, such as coextrusion of the therapeutic drug with the polymeric material.  The therapeutic drug is dispersed and incorporated into the polymer as small particles, preferably having a maximum cross-sectional dimension of 10 microns.
Patent NZ-331814-A (NZ)
Title: Industrial syringe
Inventor: DANG NGUYEN THAI
IPC: G01F11/04
Filed: 1997-04-03
Abstract: A syringe as disclosed having an elongated cylindrical tube open at both a first and second end. The first open end of the tube provides both a filling and dispensing opening for the contents of the tube. A cylindrical piston is slidably mounted within the tube and has a first axial end facing the fill and dispensing opening and a second axial end facing the opposite or second opening. The piston has an outside diameter slightly smaller than the inside diameter of the tube so that an annular clearance space is formed between the tube and the piston. A wiper extends radially outwardly from the second end of the piston and frictionally engages the cylindrical internal surface of the tube. In practice, when the syringe is filled, air is compressed through the annular opening and deflects the wiper such that the air escapes out of the syringe tube. The fill material, however, is sufficiently viscous such that, after air has been expelled from the tube, the viscous material slidably displaces the piston within the interior of the tube. A novel tamper evident cap is also disclosed for closing the second end of the tube.
Patent NZ-332353-A (NZ)
Title: Topical acne treatment using nicotinamide, nicotinic acid, or an alkyl nicotinate and tea tree oil
Inventor: STATON JOHN ALEXANDER
IPC: A61K31/44
Filed: 1997-03-24
Abstract: A composition for topical treatment of acne, comprising 0.5-20% w/w of a precursor selected from nicotinamide, nicotinic acid or lower C1-4 alkyl nicotinate which generates NAD or NADP in vivo, 0.1-25%w/w tea tree oil and a pharmaceutically acceptable carrier.
Patent NZ-333991-A (NZ)
Title: method of preparing cyclohexene carboxylate derivatives
Inventor: KENT KENNETH M
IPC: B05B7/12
Filed: 1997-08-22
Abstract: The compounds of formula 5 are prepared by reacting a compound of formula 4 with a dehydrating agent wherein R1 is a cyclic hydroxy protecting group; R2 is a carboxylic protecting group; R3 is a hydroxy protecting group and each R20 is independently H or alkyl.
Patent NZ-504394-A (NZ)
Title: Method of extracting undesirable materials from capsule surfaces by exposing the capsule to super critical fluid (SCF)
Inventor: HORHOTA STEPHEN T
IPC: A61M15/00
Filed: 1998-10-05
Abstract: A method of treating hard capsules used for storing a dry, powered pharmaceutical formulation where in the capsule has supercritical fluid-extractable material on its internal surfaces which comprises exposing the hard capsule to a supercritical fluid to remove supercritical fluid-extractable material.
Patent NZ-512692-A (NZ)
Title: Sulphoalkyl ether cyclodextrin based controlled release solid pharmaceutical formulations
Inventor: STELLA VALENTINO J
IPC: C08B37/16
Filed: 2000-01-11
Abstract: Solid pharmaceutical formulations consist of a core comprising a physical mixture of one or more sulphoalkyl ester cyclodextrin, a release rate modifier and a therapeutic agent. A major portion of the therapeutic agent is not complexed to the sulphoalkyl ester cyclodextrin. The therapeutic agent of core is released at a controlled rate in the absence of the release rate modifying coating surrounding the core.
Patent NZ-512830-A (NZ)
Title: Triazole compounds with dopamine-D3-receptor affinity
Inventor: STARCK DOROTHEA
IPC: C07D403/04
Filed: 2000-01-12
Abstract: A triazole derivative or a salt thereof has the formula (I) and is useful for treating disease which respond to the influence of dopamine D3 receptor antagonists or agonists wherein: R1 is H, optionally substituted alkyl, cycloalkyl or phenyl; R2 is H, optionally substituted alkyl, alkoxy, alkylthio, alkenyl, alkynyl, cycloalkyl, halogen, CN, COOR3, CONR3R4, NR3R4, SO2R3, SO2NR3R4 or optionally substituted phenyl, naphthyl, or 5 or 6 membered heterocyclic radical having 1 to 4 heteroatoms of O, S or N; R3 and R4 is H, optionally substituted alkyl or phenyl; A is C4-10 alkylene or C3-10 alkylene having a Z group with Z being O, S, CONR3, COO, CO, cycloalkyl or a double or triple bond; B is a group of formula (II); X is CH2 or CH2CH2; R5 is H, optionally substituted alkyl, alkenyl, haloalkenyl, alkynyl or cycloalkyl; R6, R7 or R8 are independently H, optionally substituted alkyl, OH, alkoxy, SH, alkylthio, alkenyl, alkynyl, halogen, CN, NO2, SO2R3, SO2NR3R4, SO2R3, NHSO2R3 or NR3R4.
Patent NZ-516476-A (NZ)
Title: A hG-CSF in which at least one of the 1st, 2nd, 3rd and 17th amino acids is different from those of wild-type hG-CSF
Inventor: KWON SE-CHANG
IPC: C12N15/09
Filed: 2000-07-07
Abstract: A modified human granulocyte-colony stimulating factor (hG-CSF)   is   produced   by  culturing   a   microorganism transformed  with  an expression vector  comprising  a  gene encoding  a  modified  hG-CSF to  produce  and  secrete  the modified  hG-CSF  to periplasm, said modified  hG-CSF  being obtained by replacing at least one of the 1st, 2nd, 3rd  and 17th  amino  acids of wild-type hG-CSF (SEQ ID NO:  2)  with other amino acids.
Patent NZ-524446-A (NZ)
Title: New strains of lactobacillus paracasei and their use in the manufacture of cheese and other dairy food products
Inventor: ANTONSSON MARTIN
IPC: A23C9/123
Filed: 2001-08-28
Abstract: The isolated probiotic strains Lactobacillus paracasei 8700:2,  DSM  13434  and Lactobacillus  paracasei  02A,  DSM 13432  are described. The strains can be used as an  adjunct in  the  manufacture of cheese and can be present  in  other diary  food products, preferably in yoghurt or hard or semi- hard cheese.
Patent NZ-524630-A (NZ)
Title: Phase & envelope generation in an EER system
Inventor: MANN STEPHEN IAN
IPC: H03F1/32
Filed: 2003-03-07
Abstract: Phase and envelope information is generated from a digital Cartesian signal by rotating the signal by matrix multiplication using feedback of approximated phase information to represent incremental changes of phase between subsequent digital samples of the signal, approximating the phase and envelope information using the Cartesian components of the rotated signal and providing the Cartesian signal at a sample rate that is selected to reduce the magnitude of the incremental changes of phase. A digital processing system generates the phase and envelope information from an input Cartesian signal and includes a rotation subsystem that receives a sample of the input Cartesian signal and calculated a rotation of the signal toward a selected Cartesian axis using feedback of phase information generated from a preceding sample of the signal, an approximation subsystem that receives a sample of the rotated input signal from the rotation subsystem and calculates an approximate increment of phase of the signal in relation to the preceding sample of the signal , and an output subsystem that generates the phase information by adding the approximate increment of phase to the feedback phase information and generates the envelope information as the amplitude of the rotated signal along the selected axis.
Patent NZ-525582-A (NZ)
Title: Methods and systems for tracking silvicultural information using electronically programmable tags that are updated during the product cycle of a tree
Inventor: CARLSON WILLIAM C
IPC: G08B21/00
Filed: 2003-04-30
Abstract: A system for tracking silvicultural information during the product cycle of a tree, the system includes:- (a) at least one electronically programmable tag that stores a first portion of silviculture information, such as the identity and location of a tree, this tag is to be attached or located proximate to the tree. (b) a database containing a second portion of the silviculture information, such as cultivation and harvesting information, this second portion of information being associated with the first portion of information, and (c) computer means of tracking the first and second portions of silviculture information, this includes accessing the first portion of information during the growth, harvesting and processing stages of the tree.
Patent NZ-525726-A (NZ)
Title: Oral pharmaceutical composition containing a block copolymer
Inventor: BATEMAN NICOLA
IPC: A61K31/496
Filed: 2001-11-07
Abstract: Disclosed is a combination of a pharmaceutically active compound and a diblock copolymer of formula AB or BA or a triblock copolymer of formula ABA or BAB or a multiblock copolymer having repeating BA or AB units of formula A(BA)n or B(AB)n, where n is an integer and wherein: A is selected from poly D-, L-, DL-lactic acid; poly D-, L-, DL-lactide; poly-glycolic acid; polyglycolide; polylactide-co-glycolide; poly-å-caprolactone; and poly(3-hydroxybutyric acid); B is selected from hydrophilic polymers consisting of polyvinylalcohol; polyvinylpyrrolidone; polyethylene oxide; and polyethylene glycol; or B may itself be a copolymer; and Wherein the ratio of copolymer to compound is from 10:1 to 0.25:1.
Patent NZ-525951-A (NZ)
Title: A Method and System for Prioritising Incoming Communications which is placed in an ordered queue on the basis of an associated priority indicator
Inventor: SHELTON RICHARD HENRY
IPC: H04M3/523
Filed: 2003-05-15
Abstract: A system for prioritising incoming communications that comprises: (a) A processor for identifying the origin of each of at least some of the incoming communications by an origin identifier; (b) A processor for associating a fixed priority indicator with each origin identifier in a set of origin identifiers such that each priority identifier in unique within the set; and (c) A processor for placing each incoming communication into an ordered queue on the basis of its associated priority indicator.
Patent NZ-531715-A (NZ)
Title: Joiner assembly with forms for fixed and sliding panels covered by same cladding
Inventor: HANCOCK MICHAEL JOHN
IPC: E06B3/263
Filed: 2004-03-11
Abstract: An exterior surface of a fixed form 12 is covered with cladding material 19. The interior surface of a sliding panel form 14 (adapted to receive a sliding panel as shown) is covered with the same cladding material 19. The construction is stated to provide aesthetic and reduced heat transfer benefits.
Patent NZ-533308-A (NZ)
Title: Thrombopoietin mimetics
Inventor: DUFFY KEVIN J
IPC: C12N5/0789
Filed: 2001-05-24
Abstract: Thrombopoietin (TPO) mimetics and their use as promoters of thrombopoiesis and megakaryocytopoiesis are disclosed. Also disclosed are processes and intermediates used in the preparation of these compounds; a method of treating thrombocytopenia, in a mammal, including a human, in need thereof which comprises administering to such mammal an effective amount of a selected hydroxy-1-azobenzene derivative. (62) Divided out of 522474
Patent NZ-535054-A (NZ)
Title: 5-Substituted-alkylaminopyrazole derivatives as pesticides
Inventor: CHOU DAVID TEH-WEI
IPC: C07D231/44
Filed: 2003-02-27
Abstract: Disclosed is a method for controlling parasites in or on a non-human animal comprising administering to the non-human animal a parasiticidally effective amount of a 5-substiuted-alkylaminopyrazole derivative of formula (I), wherein: R1 is CN, W is C-halogen, C-CH3 or N, R2 is H, halogen or CH3, R3 is haloalkyl, haloalkoxy or S(O)p-haloalkyl, R4 is H, alkenyl, halo-alkenyl, alkynyl, halo-alknynl, cycloalkyl, CO-(CH2)q-R7, COR8, CO-(CH2)q-R9, -CO-haloalkynyl, cycloalkyl, CO-(CH2)q-R7, COR8, CO-(CH2)q-R9, -CO-alkyl-alkoxy, -CO2-(CH2)q-R7, CO2R8, -CO2-(CH2)q-R9, -CO2-cycloalkyl, -CO2-alkyl-cycloalkyl, -CO2-alkyl-cycloalkyl, -CO2-alkenyl, -CO2-alknyl, CONR10R11, -CH2R7, -CH2R9, OR7, OR8 or OR9, or optionally substituted alkyl, and the remaining substituents are defined herein.