baber/WOPTO huggingface dataset:
Patent PT-670839-E (PT)
Inventor: ZARINI FRANCO
IPC: C07D/
Filed: 1994-09-15
Abstract: A process for preparing the 9-amino camptothecin of formula (I) <CHEM>  said process comprising:     (1) reacting a compound of formula (III) <CHEM> wherein the hydroxy group on ring A is in the 10- or 12-position, with a nitrating agent, so obtaining a corresponding compound of formula (IV) <CHEM>   (2) converting the compound of formula (IV) into a corresponding compound of formula (V) <CHEM>  wherein XO is a group that can be removed reductively; and (3) reductively removing the said XO group and reducing the nitro group of the compound of formula (V), so obtaining the 9-amino camptothecin of formula (I), a known antitumor compound.   The present invention includes also in its scope compounds having the above reported formula (V) and compound of formula (VII) <CHEM> which are endowed with antitumor activity.p
Patent PT-772407-E (PT)
Inventor: ALCARAZ GERARD
IPC: A23L3/00
Filed: 1995-06-22
Abstract: PCT No. PCT/FR95/00835 Sec. 371 Date Mar. 11, 1997 Sec. 102(e) Date Mar. 11, 1997 PCT Filed Jun. 22, 1995 PCT Pub. No. WO95/35039 PCT Pub. Date Dec. 28, 1995A method for preparing a product to be pasteurized, particularly a food product, to ensure a long shelf life without affecting the quality or the nutritional, rheological and organoleptic properties thereof. The method comprises determining the cooking threshold value (Cg) of the product, measuring its pH and rH2, and deducing the corresponding pasteurization threshold value (P) therefrom, in particular by using a curve shown, then measuring the ratio (Aw) between the free water and total water contained in the product, and determining the heating curve of a heat treatment carried out on the product in such a way that the cooking threshold value is reached as the pasteurization threshold value is also reached and preferably exceeded, while at the same time the product is in a physical and chemical condition which corresponds to the Clostridium botulinum germ inhibition region.
Patent PT-787011-E (PT)
Title: Microemulsion preconcentrate comprising a macrolide
Inventor: SEDRANI RICHARD
IPC: A61P31/04
Filed: 1995-10-25
Abstract: This invention provides a microemulsion pre-concentrate comprising a difficultly soluble agent and a carrier medium comprising: 1) a hydrophilic phase which comprises dimethyisosorbide and/or a lower alkyl alkanoic ester, 2) a lipophilic phase, and 3) a surfactant. The active agent may be a cyclosporine or a macrolide. In another aspect, this invention provides a pharmaceutical composition for enteral or parenteral administration comprising a macrolide and an acid.
Patent PT-792108-E (PT)
Inventor: GRUBZAK YANCEY
IPC: A23G9/22
Filed: 1995-10-05
Abstract: The present invention relates to an apparatus for the sequential assembly of a sandwich-type comestible product, such as an ice cream sandwich, and comprises an essentially horizontal conveyor, sequentially placed wafer dispensing means and an extrusion assembly for the dispensing of a regulated amount of a comestible material. The wafer dispensing means and the extrusion means are mounted in cantilevered fashion on a vertical wall, thereby facilitating the ease of repair, removal for retrofitting and cleaning. In addition, the extruder nozzles and the wafer chutes are individually removable and may be replaced with like components of differing internal diameter, to accommodate the preparation of sandwich-type comestible products of differing size and shape.
Patent PT-744605-E (PT)
Inventor: LEHMANN MARTIN
IPC: G01M3/32
Filed: 1996-09-04
Abstract: The testing chamber (1) has a cover (3) for sealing the open end of the inverted container, which acts simultaneously as a carrier for the latter and which incorporates closure elements (8) cooperating with the inside wall of the testing chamber. The closure elements are provided by transverse bolts, with angles surfaces (8') at their outer ends, fitting into corresponding recesses (9) in the chamber inside wall, to lock the cover during the leakage testing procedure. The bolts are operated by a rod (10) allowing the cover to be used simultaneously for opening and closing the test chamber.
Patent PT-850493-E (PT)
Inventor: TILLMANN HEINZ GUNTER
IPC: H01M10/12
Filed: 1996-07-09
Abstract: A process is disclosed for manufacturing lead electrodes for accumulators. Lead grid elements (2, 3) are produced, provided with an active mass (5) and coated on both sides with glass microfibres (6, 7). In order to automate the process to a large extent, the introduction of the active mass and the coating with glass microfibres, which immediately follows the introduction of the active mass, are automatically carried out in a continuous process, and the glass microfibres are then cut (9) so that they do not project beyond the edges.
Patent PT-936923-E (PT)
Inventor: MAINI RAVINDER NATH
IPC: C07K16/24
Filed: 1997-11-17
Abstract: Methods for treating and/or preventing a TNF-mediated disease in an individual are disclosed. Also disclosed are compositions comprising a TNF antagonist and an IL-12 antagonist. TNF-mediated diseases include rheumatoid arthritis, Crohn's disease, and acute and chronic immune diseases associated with transplantation.
Patent PT-853917-E (PT)
Inventor: BUMB GERMANN
IPC: A47L9/28
Filed: 1998-01-09
Abstract: The vacuum cleaner has a base apparatus (1), a suction hose (6), an apparatus handle and different accessories (7) which can be attached selectively. The motor is controllable in its power and the control is undertaken furthermore by three power regulators. These are each connected to a control unit through its own connecting cable and a predetermined priority sequence leads to the activation of only one regulator. All the power regulators lead to almost the same voltage drop in the respective connecting cables. An accessory for the vacuum cleaner has a switchable recognition resistance in the connecting cable of a power regulator.
Patent PT-983087-E (PT)
Inventor: ODILE LEROY
IPC: A61P31/00
Filed: 1998-05-14
Abstract: The invention concerns a pharmaceutical composition for treating or preventing a certain number of infections caused by pathogenic agents such as bacteria, comprising as immunogen, one or several polyosides derived from one or several pathogenic agents. The polyosides are in the form of conjugates, coupled with a carrier protein. The composition contains at least two types of conjugates, each being at least characterised by a different protein carrier.
Patent PT-1002186-E (PT)
Inventor: PALOCZ-ANDRESEN MICHAEL
IPC: G01M99/00
Filed: 1998-11-04
Abstract: This invention pertains to the emission control in motor vehicles but also in ships, airplanes and diesel locomotives. The control system may either be fitted into new vehicles by the manufacturer or be retrofitted by the driver in older vehicles. An adsorption system serves to reduce the vehicle emissions during the cold-start period, in case of malfunctions in the engine or in the exhaust gas after-treatment system and in times of high quantities of pollutants in the atmosphere. To regenerate the adsorbent masses, the pollutants will be desorbed, introduced into the combustion chamber and burned.
Patent PT-1045702-E (PT)
Title: Methods of controlling cell differentiation and growth using a fusion protein and a drug
Inventor: BLAU CARL ANTHONY
IPC: A61K48/00
Filed: 1999-01-07
Abstract: This invention involves methods and materials for conferring a direct proliferative advantage on a genetically modified subpopulation of cells. Selection is then accomplished by exerting a positive selective stimulus on the engineered cells rather than a negative pressure on nonengineered cells.
Patent IE-780110-L (IE)
Title: Amides.
IPC: C07C231/12
Filed: 1978-01-18
Abstract: Compounds of the general formula: <IMAGE> and non-toxic physiologically acceptable salts thereof, in which R1 is a halogen atom or a group NR2R3; R2 and R3, which may be the same or different, are hydrogen or (C1-C6) straight or branched chain alkyl or R2 and R3 may, together with the nitrogen atom, form a 5 or 6 membered heterocyclic ring which may contain a further hetero atom selected from O, N or S; or R2 may be hydrogen and R3 may by group R4CO or R4SO2 where R4 is hydrogen or alkyl (C1-4); R5 is hydrogen or one or more halogen atoms or hydroxy or alkoxy (C1-4) groups; and X is CH2, O or a group NR6 where R6 is hydrogen or alkyl (C1-4). These compounds block beta -adrenoreceptors.
[US4140713A]
Patent IE-890187-L (IE)
Title: Easily disposable psyllium compositions
IPC: A23L1/308
Filed: 1989-01-23
Abstract: Powdered psyllium seek husks are rendered rapidly and uniformly dispersible in water by admixing a solvent selected from the group consisting of benzyl alcohol, propylene glycol, triacetin and mixtures thereof with powdered psyllium seed husks.
[EP0344116A1]
Patent IE-880530-L (IE)
Title: Method of treating wastewater sludge
IPC: C02F11/13
Filed: 1988-02-26
Abstract: A method of decontaminating wastewater sludge to a level that meets or exceeds USEPA Process to Further Reduce Pathogens standards, wherein lime or kiln dust and/or other alkaline materials are mixed with wastewater sludge in sufficient quantity to raise the pH of the mixture to 12 and above for a predetermined time and drying the resulting mixture.
[EP0283153A1]
Patent IE-880664-L (IE)
Title: Compositions and methods for treating gastrointestinal¹disorders
IPC: A61K33/24
Filed: 1988-03-08
Abstract: The present invention relates to pharmaceutical compositions useful for treating or preventing gastrointestinal disorders. These compositions comprise a bismuth-containing agent, preferably a campyloabcter-inhibiting bismuth-containing agent such as bismuth subsalicylate and bismuth subcitrate, and a histamine-2 receptor blocking anti-secretory agent such as cimetidine. The present invention further relates to methods for treating or preventing gastrointestinal disorders in humans or lower animals by administering a bismuth-containing agent and a histamine-2 receptor blocking anti-secretory agent.
Patent IE-34235-L (IE)
Title: 6, 7-benzomorphans
IPC: C07D211/74
Filed: 1970-05-26
Abstract: 6,7-BENZOMORPHAN DERIVATIVES HAVING ANALGESIC AND MORPHINE-ANTAGONISTIC PROPERTIES ARE OF THE FORMULA IN WHICH THE SUBSTITUENTS R are either lower alkyl groups or groups which, together with the carbon atom to which they are bonded, form a cycloaliphatic ring, and the substituents R1, R2 and R3 may or may not be made and, if made, R1 represents either a hydrogen atom or an alkyl, haloalkyl, alkenyl, alkinyl, aralkyl, cycloalkenyl, cycloalkylalkyl, cycloalkenylalkyl or cycloalkylidine-alkyl group, R2 is an alkyl, aryl, heteroaryl or aralkyl group, and R3 is a hydrogen atom or an hydroxy, alkoxy, alkoxy-alkoxy or acyloxy group. Such 6,7-benzomorphans may be in the form of their optically active enantiomers and/or their therapeutically acceptable salts. There are also disclosed methods for producing such 6,7-benzomorphan derivatives, and intermediates useful in such production.
[US3764606A]
Patent FI-822504-L (FI)
Inventor: MONDT JOSEF
IPC: C08F220/10
Filed: 1982-07-14
Abstract: 1. Claims for the Contracting states : BE, CH, DE, FR, GB, IT, LI, LU, NL, SE An aqueous plastics dispersion based on a copolymer of an acrylic monomer, a vinyl monomer and a functional monomer capable of crosslinking, containing at least one emulsifier consisting of a fluorinated surfactant, which dispersion is obtained by a radically initated emulsion copolymerization of a monomer mixture containing I) 20 to 80% by weight of a "hardening" component A from the group comprising methacrylic acid ester, the homopolymer of which has a glass transition temperature TG above + 50 degrees C, styrene, vinyltoluene or vinylxylene, or mixtures of these components, the aromatic vinyl monomer contributing not more than 50% by weight to the total amount of all monomers, II) 20 to 80% by weight of a "plasticizing" component B from the group comprising acrylic acid ester or methacrylic acid ester, the homopolymer of which has a glass transition temperature TG below + 50 degrees C, or mixtures of these components, III) in each case relative to the total of A + B = 100, 1) 3 to 18% by weight of a monoolefinic unsaturated monomer having a hydroxyl group and 2) 0,5 to 10% by weight of an alpha-, beta- unsaturated monocarboxylic acid and/or an unsaturated dicarboxylic acid, characterized in that the copolymerization was carried out in the pressence of an anionic fluorinated surfactant having a perfluoroalkyl radical of 2 to 20 C atoms or a perfluoroaralkyl radical of 7 to 30 C atoms as the emulsifier or as a component of the mixture of emulsifiers, and the particle diameters of the resulting dispersion copolymer are in the range of from 0,05 to 0,2 mu m. 1. Claims for the Contracting state : AT A process for the preparation of an aqueous plastics dispersion by copolymerization of a) 20 to 80% by weight of an ester of methacrylic acid, the homopolymer of which has a glass temperature TG above + 50 degrees C, or styrene, vinyltoluene or vinylxylene, or a mixture of these monomers, the aromatic monomer contributing not more than 50% by weight to the total amount of all monomers, as the hardening component, b) 20 to 80% by weight of an ester of acrylic acid or of methacrylic acid, the homopolymer of which has a glass temperature TG below + 50 degrees C, or a mixture of these monomers, as the plasticizing component, c) in each case relative to the total of A + B = 100, 1) 3 to 18% by weight of a monoolefinic unsaturated monomer having a hydroxyl group and 2) 0,5 to 10% by weight of an alpha-, beta- unsaturated monocarboxylic acid and/or an unsaturated dicarboxylic acid, in an aqueous medium in the presence of a radical-forming initiator and an emulsifier or a mixture of several emulsifiers, characterized in that the copolymerization is carried out in the presence of an anionic fluorinated surfactant having a perfluoralkyl radical of 2 to 20 C atoms or a perfluoraoaralkyl radical of 7 to 30 C atoms as the emulsifier or as a component of the mixture of emulsifier, and the particle diameters of the resulting dispersion copolymer are in the range of from 0.05 to 0.2 mu m.
Patent FI-850828-L (FI)
Inventor: TOSCANO LUCIANO
IPC: C07H17/08
Filed: 1985-02-28
Abstract: (8S)-8-fluoroerythromycin derivatives of formulawhereinR is an optionally substituted alkyl, alkenyl or phenyl groupR' is hydrogen or methyl andR" is hydrogen or hydroxy,may be prepared by fluorination of the corresponding 8,9-anhydroerythromycin 6,9-hemiketals with perchloryl fluoride in the presence of a compound ROH in strictly anhydrous conditions.The new compounds as well as their pharmaceutically acceptable esters, salts and salt-esters may be employed as the active ingredients of pharmaceutical compositions for antibacterial use suitable for oral administration.
Patent FI-853211-L (FI)
Inventor: KOENIG HANS-BODO
IPC: C07D499/70
Filed: 1985-08-21
Abstract: 1. Sodium salt of D-6-{alpha-[(2-oxo-3- furfurylideneamino-imidazolidin-1-yl)-carbonylamino]-2- thienylacetamido}-penicillanic acid of the formula (I)  see diagramm : EP0176716,P8,F2  in pure crystalline form, characterized by the following NMR signals : delta = 9.36 (1H), 9.23 (1H), 7.8 (2H), 7.5 (1H), 7.25 (1H), 7.05 (1H), 6.89 (1H), 6.62 (1H), 6.2 (1H), 5.74 (1H), 5.56 (1H), 4.35 (1H), 3.92 (4H), 1.6 (3H) and 1,5 ppm (3H) (in DMF-d7 ).
Patent IE-841282-L (IE)
Title: Manufacture of non-woven sheet
IPC: D04H1/46
Filed: 1984-05-23
Abstract: A process for the treatment of non-woven sheets made of synthetic textiles containing two constituents arranged side-by-side, one based on polyamide (polyhexamethyleneadipamide) and the other based on polyester (polyethylene glycol terephthalate), in which the following steps are carried out: (a) conversion to a sheet of the crimped textile having an overall linear density of less than 2 dtex, (b) optional needle bonding of the sheet, and (c) chemical treatment at low temperature in an aqueous solution of a swelling product for one of the constituents, permitting contraction and at least partial separation of the two constituents of the textile, the strands of which each then have a denier of less than 1 dtex. Swelling product: aqueous solution of formic acid at a concentration of 50% to 70%, preferably of between 55% and 65%, and at a temperature of between 5 DEG C. and 40 DEG C., preferably of between 18 DEG C. and 25 DEG C. The non-woven sheets obtained, having characteristics enabling them to be used in the majority of textile applications such as clothing, furnishing and the like.
[US4560385A]
Patent IE-38093-L (IE)
Title: Calcination of gypsum
IPC: C04B11/024
Filed: 1973-08-16
Abstract: 1438632 Calcination of gypsum BPB INDUSTRIES Ltd 15 Aug 1973 [1 Sept 1972] 40748/72 Heading C1A A process for the calcination of gypsum comprises introducing continuously finely divided gypsum together with an oxidizing agent into a calcination vessel, in which a mass of the gypsum is heated to dehydrate it and is maintained in a fluidized condition by the water vapour evolved by the gypsum, and continuously discharging a calcined product consisting subsubstantially of calcium sulphate hemihydrate from the vessel being maintained at a temperature below 150 C. It is preferred to carry out the process continuously in a kettle, according to B.P. 1,018,464, wherein the fluidization is brought about solely by the evolution of water vapour from the mass undergoing calcination at 120-140 C. and with a residue time of 60- 145 minutes in the kettle. The preferred anodizing agent is calcium chloride used in 0À05- 0À1% by wt. concentration based on the gypsum.
[GB1438632A]
Patent IE-39597-L (IE)
Title: Maintaining the pressure in a vacuum system
IPC: A01J5/04
Filed: 1974-07-09
Abstract: 1455218 Milking machines ALFA-LAVAL AB 30 July 1974 [11 Oct 1973] 33613/74 Heading AIM [Also in Division G3] The vacuum level in a machine milking plant is controlled by a device in which an increase in vacuum separates a pilot valve 4 from its seat 3 to decrease the pressure in a pipe 15 and above a diaphragm 18 to lift an air admission valve 26. A filter 13 and an adjustable needle valve 10 allow air to bleed past the valve 4 into the system under normal conditions. A screw 9 adjusts the load on the pilot while a joint 29 permits the valve 26 to be self-aligning. The pilot valve may be loaded by a weight.
[SE7313806L]
Patent IE-871740-L (IE)
Title: Calendar roll controller
IPC: B29C35/04
Filed: 1987-06-29
Abstract: An electrical air heater for a calender roll diameter control device is described. The heater comprises a tube for directing a flow of air along the inside of the tube from a plenum toward an object which is to be heated. An electrically resistive heating element is mounted inside the tube to heat the flow of air as it flows from the rear to the front of the tube. Since the air is heated by the heating element inside the tube, the air is coolest when it first enters the tube and hottest where it escapes at the front of the tube. Similarly, the heating element is cooled by the air and is, therefore, hottest near the front of the tube where the heated air escapes. The hotter front end of the heating element tends to burn out faster than the cooler end of the heating element. To prolong the life of the heater, openings are provided in the tube wall to admit a flow of cooling air at the hottest part of the heating element.
[US4738196A]
Patent IE-821899-L (IE)
Title: Heat exchanger
IPC: F28D13/00
Filed: 1982-08-06
Abstract: A fluidized bed heat exchanger in which a perforated plate is disposed within a housing for supporting a bed of particulate material. Air is passed through the plate to fluidize the particulate material and a mixture of air and additional particulate material is introduced to said bed and deflected into said bed in a manner to induce diffusion and circulation of the bed materials in the bed.
Patent IE-38611-L (IE)
Title: Sydnone derivatives.
IPC: C07D271/04
Filed: 1973-12-05
Abstract: Preparation and the valuable anti-inflammatory and antibiotic properties of substituted sydnones, represented by the formula WHEREIN R is hydrogen, lower alkyl, phenyl or bromo, Alk is alkylene having more than 1 and fewer than 5 carbon atoms, x is oxygen, thio, sulfinyl or sulfonyl, x is 0 or 1, and Ar is naphthyl, phenyl or substituted phenyl, preferably having an arylthioalkyl substituent, as typified by 3-[2-(phenylthio)ethyl]sydnone, are disclosed.
[US3883548A]
Patent IE-782426-L (IE)
Title: Trapped gulley
IPC: E03F5/04
Filed: 1978-12-07
Abstract: A drain trap has a housing in the form of a four-sided outer vessel with a closed bottom and with a lateral outlet extending from one of its sides, this housing receiving an insert which forms a closed-bottom inner vessel of downwardly converging frustopyramidal shape spacedly surrounded on three sides by a skirt depending from the top of the insert and defining with three apertured walls of the inner vessel a downwardly open chamber communicating with a space beneath that vessel. The fourth side of the inner vessel is solid and spacedly confronts a partition which rises from the bottom of the outer vessel and has an overflow edge across which incoming liquid from the aforementioned chamber may reach the lateral outlet.
[US4275760A]
Patent IE-802694-L (IE)
Title: Rolling apparatus for wire mesh
IPC: B21F33/00
Filed: 1980-12-19
Abstract: Simple twist wire net in which adjacent rows can pivot relative to each other is folded, accordian fashion, and rolled to form a compact roll. Driven strands in the form of belts or chains, spaced apart a distance equal to the distance between valleys of the folded net, engage in the valleys to maintain the accordian folded rows aligned and to form the compact roll.
[US4389025A]
Patent IE-853337-L (IE)
Title: Processing whey and/or permeate from a cheese-making process
IPC: A23C1/00
Filed: 1985-12-31
Abstract: A method of and an apparatus for converting liquid whey or permeate from a cheese-making process (20) to a non-caking powder comprising vacuum evaporating the liquid whey including using a finishing evaporator (44), until the whey is about 75% solid, the lactose which is converted into its alpha-monohydrate form by a cooled heat exchanger (50), after which a spin flash dryer (60) having a hot air fluidized bed converts the whey into a non-caking powder.
[WO8603942A1]
Patent IE-883820-L (IE)
Title: Piperidinylcyclopentylheptenoic acids compositions
IPC: A61K31/445
Filed: 1988-12-21
Abstract: AQUEOUS FORMULATIONS CONTAINING A PIPERIDINYLCYCLOPENTYLHEPTENOIC ACID DERIVATIVE Aqueous formulations comprising ¢1R-¢1.alpha.(Z),2.beta.,3.beta.,5.alpha.!!-(+)-7-¢5-¢¢(1,1'-biphenyl)-4-yl!methoxy!-3-hydroxy-2-(1-piperidinyl) cyclopentyl!-4-heptenoic acid or its hydrochloride salt and an unsubstituted or substituted .alpha.-, .beta.- or .gamma.- cyclodextrin have been found which are particularly useful in the treatment or prophylexis of conditions mediated by thromboxene A2. Suitable aqueous formulations include injections, oral preparations such as syrups and capsules and inhalation preparations.
[CA1328078C]
Patent NO-783491-L (NO)
Title: Fremgangsmaate ved fremstilling av produkter av armert herdeplast
Inventor: HANSTEEN CARSTEN B
IPC: B29C70/50
Filed: 1978-10-16
Abstract: Fremgangsmåte ved fremstilling av produkter av armert herdeplast