baber/WOPTO huggingface dataset:
Patent NZ-597030-A (NZ)
Title: Method for treatment of diseases
Inventor: BAR-OR DAVID
IPC: A61K31/58
Filed: 2010-06-22
Abstract: 597030 Disclosed is a vascular-hyperpermeability-inhibiting amount of a compound selected from danazol and pharmaceutically acceptable salts of danazol, for use for treating macular edema in an animal in need thereof.
Patent NZ-602949-A (NZ)
Title: Methods for treating glucose metabolic disorders
Inventor: RUFF KEVIN
IPC: A61K35/57
Filed: 2011-04-12
Abstract: Disclosed are methods for treating a disease or condition associated with abnormal glucose metabolism. In another aspect, the disclosure relates to a method for reducing incidence or progression of insulin-dependent diabetes mellitus. The methods include orally administering to a mammal in need thereof an effective amount of a composition, which includes a naturally occurring material derived from eggshell, eggshell membrane, or a combination thereof. Particularly disclosed is treating diabetes mellitus with a composition that comprises powdered eggshell membrane in insulin-dependant diabetic mammals.
Patent NZ-624783-A (NZ)
Title: Modulation of huntingtin expression
Inventor: STANEK LISA
IPC: C12N15/11
Filed: 2010-09-10
Abstract: Disclosed is the of a modified single stranded oligonucleotide consisting of 12 to 30 linked nucleosides in the manufacture of a pharmaceutical composition for the treatment of an animal, wherein said modified oligonucleotide has a nucleobase sequence which is at least 90% complementary to human huntingtin (HTT) and said treatment comprises intrastriatal administration of the composition to the animal.
Patent NZ-700501-A (NZ)
Title: Mount for a panel
Inventor: WAYNE AUSTIN
IPC: E06B3/58
Filed: 2013-09-27
Abstract: There is provided a mount (1) for a panel such as a glass pane for use as a balustrade. The mount (1) comprises a body (2) comprising at least one curved side surface (3a) and at least one clamping member (5a) configured to clamp an edge of the panel with respect to the body (2) and comprising at least one adjacent side surface (5c) configured to cooperate with the curved surface (3a) of the body (2) to provide for pivoting of the panel with respect to the body (2) on actuation of at least two actuators (6) spaced vertically on the same side of the panel and that are adjustable from the same side of the panel.
Patent NZ-718802-A (NZ)
Title: Icotinib-containing topical skin pharmaceutical composition and use thereof
Inventor: WANG YINXIANG
IPC: A61P35/00
Filed: 2014-10-11
Abstract: Disclosed are topical preparations for inhibiting tyrosine kinase and preparation methods thereof, and especially topical pharmaceutical compositions for inhibiting tyrosine kinase and preparation methods thereof. The active ingredient of the topical preparations is Icotinib or a pharmaceutically acceptable salt thereof. The preparations are suitable for topical application, with minimal skin irritation, no adverse reactions such as pruritus, burning sensations, tingling, dry skin, erythema and rashes, without parahormone-related side effects such as skin atrophy, pigmentation or hypopigmentation for long-term use, as well as no related dermatological symptoms after drug withdrawal.
Patent NZ-718931-A (NZ)
Title: Oncolytic adenoviruses armed with heterologous genes
Inventor: CHAMPION BRIAN ROBERT
IPC: C12N7/00
Filed: 2014-10-24
Abstract: The present disclosure relates to a group B adenovirus comprising a sequence of formula (I): 5’ITR-B1-BA-B2-BX-BB-BY-B3-3’ITR wherein: B1 is a bond or comprises: E1A, E1B or E1A-E1B; BA comprises-E2B-L1-L2-L3-E2A-L4; B2 is a bond or comprises: E3; BX is a bond or a DNA sequence comprising: a restriction site, one or more transgenes or both; BB comprises L5; BY comprises a transgene cassette comprising a transgene and a splice acceptor sequence under the control of an endogenous promoter; B3 is a bond or comprises: E4; pharmaceutical compositions comprising the same and use of the viruses and compositions in treatment, particularly in the treatment of cancer. The disclosure also extends to plasmids and processes employed to prepare the said viruses.
Patent NZ-721138-A (NZ)
Title: Bispecific t cell activating antigen binding molecules
Inventor: FREIMOSER-GRUNDSCHOBER ANNE
IPC: C07K16/30
Filed: 2012-08-21
Abstract: Discloses CD3 binding bispecific T cell activating antigen binding molecules comprising a crossover Fab molecule wherein either the variable or the constant regions of the Fab light chain and the Fab heavy chain are exchanged. Either the second antigen binding moiety is fused at the C-terminus of the Fab heavy chain to the N-terminus of the Fab heavy chain of the first antigen binding moiety and the first antigen binding moiety is fused at the C-terminus of the Fab heavy chain to the N-terminus of the first or second subunit of the Fc domain, or (ii) the first antigen binding moiety is fused at the C- terminus of the Fab heavy chain to the N-terminus of the Fab heavy chain of the second antigen binding moiety and the second antigen binding moiety is fused at the C-terminus of the Fab heavy chain to the N-terminus of the first or the second subunit of the Fc domain. The T cell activating bispecific antigen binding molecule comprises not more than one antigen binding moiety capable of specific binding to CD3.
Patent NZ-722645-A (NZ)
Title: Processing biomass
Inventor: MEDOFF MARSHALL
IPC: C12P7/10
Filed: 2011-10-18
Abstract: Disclosed is a method for processing biomass comprising: irradiating a lignocellulosic material with an electron beam, the lignocellulosic material comprising corn cobs and having a particle size of less than 1 mm, and combining the irradiated lignocellulosic material with an enzyme and/or a microorganism, the enzyme and/or microorganism utilizing the irradiated lignocellulosic material to produce the product. The products can be produced for example from saccharification or fermentation.
Patent NZ-725517-A (NZ)
Title: Bioceramic compositions and biomodulatory uses thereof
Inventor: VISSMAN SHANNON
IPC: A61N5/00
Filed: 2015-05-01
Abstract: The subject matter described herein is directed to articles, compositions, systems, and methods of using and preparing bioceramic compositions and to the bioceramic compositions. A bioceramic composition of the disclosure radiates infrared energy or rays and can be used in the treatment of various conditions. A bioceramic composition disclosed herein comprises tourmaline, kaolinite, aluminium oxide, silicon dioxide, and titanium oxide. Methods of plant cultivation by applying a composition comprising the bioceramic are claimed.
Patent NZ-728676-A (NZ)
Title: Optical fiber tray and optical fiber management tray assembly
Inventor: ABBIATI FABIO
IPC: G02B6/46
Filed: 2012-04-05
Abstract: An optical fiber management tray assembly is disclosed, including a support arm and a plurality of optical fiber trays. Each tray could safely receive both bare fibers and buffered fibers. Management of bore fibers and buffered fibers present differing challenges, such as the greater diameter of buffered fibers and the fragility of bore fibers. The tray comprises two separate and independent ports for bare and buffered fibers respectively. Each tray has a hinge in its rear side with a hinge axis for connection to the support arm. Each tray further comprises at least a first port arranged at the rear side of the tray and configured for allowing optical fibers of a first type to enter/exit the tray, wherein said optical fibers of the first type are buffered optical fibers and comprise a core, a cladding, a coating and a buffer layer around said coating. The tray also comprises a guiding member comprising a second port substantially on the hinge axis and configured for allowing optical fibers of a second type to enter the tray along said hinge axis, wherein said optical fibers of the second type are bare optical fibers comprising a core, a cladding, a coating and are free from a buffer layer around said coating. The guiding member is arranged in a central region of said rear side, projects from said rear side of said tray and is independent from said at least a first port. The hinge comprises two hinge pivots and two support walls supporting said two hinge pivots, wherein said guiding member is arranged between said two support walls. The guiding member projects outwardly from the tray in such a way that the second port is at a distance from a central back wall and in such a way that the second port lies substantially on the hinge axis. The optical fiber trays are hinged to the support arm in such a way that they can be rotated around the hinge axis. The support arm comprises a section comprising two parallel section wings and a section bottom surface therebetween so that the support arm and the central back wall of the plurality of trays form a closed section for the bare fibers to the guiding members. Each of the two parallel section wings comprises a plurality of holes for said hinge pivots and a plurality of indentations for holding said optical fiber trays in a rotated configuration. The indentations and holes of one section wing face the indentations and holes of the other section wing.
Patent NZ-733912-A (NZ)
Title: Modified dnase and uses thereof
Inventor: CHEN ZELTSBURG LILACH
IPC: C12N9/16
Filed: 2016-01-04
Abstract: Modified DNase I protein in which one or more amino acids of a DNase I protein are modified non-cellularly, are provided. The modified DNase I protein exhibits a DNA hydrolytic activity in the presence of actin and an improved DNA hydrolytic activity compared to a homologous non-modified DNase I protein. Processes of preparing the modified DNase I protein and uses thereof in, for example, reducing a DNA content in sputum and/or in treating a disease or condition associated with excess extracellular DNA in a fluid, secretion or tissue of a subject, are also provided.
Patent NZ-741875-A (NZ)
Title: Canine parvovirus (cpv) virus-like particle (vlp) vaccines and uses thereof
Inventor: DAVID FREDERIC
IPC: A61K39/23
Filed: 2016-09-14
Abstract: The present invention encompasses canine parvovirus (CPV) vaccines or compositions. The vaccine or composition comprises CPV virus-like particles (VLPs) and a CPV modified-live virus (MLV), and are capable of overcoming maternally-derived antibodies (MDAs). The invention encompasses a preparation method and a use thereof. The CPV VLPs provided by the invention may be formed by the CPV VP2 protein.
Patent NZ-747411-A (NZ)
Title: Nonuniformly perforated plastic bag
Inventor: BALASUBRAMANIAN AISHWARAYA
IPC: B65D81/20
Filed: 2013-10-18
Abstract: When a Modified Atmosphere Package (”MAP”) is used to pack bananas, two different atmospheres may develop: one atmosphere surrounding the first portion of bananas and a different atmosphere surrounding the second portion of bananas. These different atmospheres can create differences in the ripening advancement and shelf life of the bananas; such differences are undesirable. Provided is a perforated plastic bag wherein the volume of said bag is 100 liters or more; wherein the average perforation diameter is 500 micrometers or less; wherein said plastic bag comprises a lower zone and a top zone, wherein the perforation density of said lower zone is greater than the perforation density of said top zone. Also provided is a method of using such a plastic bag. The plastic bag of the inventions seeks to reduce such differences in internal atmospheres in different portions of the bag when produce has been packed in those different portions of the bag. The plastic bag also seeks to provide the correct gas transport properties.
Patent NZ-752894-A (NZ)
Title: Formulations for administration of eflornithine
Inventor: LEVIN VICTOR
IPC: A61K31/198
Filed: 2017-09-29
Abstract: Eflornithine is an agent that can be used to treat glioma, especially glioma of WHO Grade II or Grade III such as anaplastic glioma. Eflornithine can suppress or prevent mutations in glioma which can cause the glioma to progress to a higher grade. The present invention describes pharmaceutical compositions in the form of a solutions for oral administration that contain from about 16.2 wt% to about 19.8 wt% of eflornithine or a pharmaceutically acceptable salt thereof, and water.
Patent NZ-753024-A (NZ)
Title: The use of inhibitors of bruton’s tyrosine kinase (btk)
Inventor: BUGGY JOSEPH
IPC: A61P35/02
Filed: 2011-06-03
Abstract: Disclosed is the use of (R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one (ibrutinib / PCI-32765) in the manufacture of a medicament for treating diffuse large B-cell lymphoma (DLBCL) in an individual in need thereof, wherein the medicament is formulated for administration of the compound once per day in an amount of about 560 mg, in a solid oral dosage form.
Patent NZ-757885-A (NZ)
Title: Packed coffee beverage containing furfuryl methyl sulfide
Inventor: YANO TARO
IPC: A23F5/24
Filed: 2018-03-14
Abstract: Provided is a coffee beverage which is reduced in bitterness regardless the liquid temperature thereof and has good after taste sharpness. The guaiacol content and the furfuryl methyl sulfide content in the beverage are adjusted to values falling within specified ranges.
Patent NZ-779158-A (NZ)
Title: Method of cleaning pipeline
Inventor: ALLRED JR
IPC: B08B9/027
Filed: 2021-01-11
Abstract: A method of cleaning a pipeline is performed by introducing a treatment composition comprising a colloidal particle dispersion having inorganic nanoparticles with an average particle size of from 500 nm or less into an interior of a pipeline to be cleaned. A pig or body is passed through the pipeline to spread the composition upon surfaces of the interior of the pipeline. The composition and materials adhering to the surfaces of the interior of the pipeline are removed to facilitate cleaning of the pipeline.
Patent NZ-783783-A (NZ)
Title: Underwater device for capturing images of a seabed
Inventor: KANDUKURI RAJA
IPC: G03B17/08
Filed: 2020-05-12
Abstract: The invention relates to an underwater apparatus having a hyperspectral camera for image-capturing of the floor of a body of water, having a first housing part, a second housing part, which is connected to the first housing part in a watertight and releasable manner and, together with the first housing part, encloses a cavity, in which the hyperspectral camera is arranged, and an electrical energy store for supplying the hyperspectral camera with electrical energy, which energy store is arranged in a different cavity, wherein the different cavity (7) is separated from the cavity by a wall segment of the first and/or second housing part.
Patent PT-101175-A (PT)
Inventor: LO JULIAN BELKNAP
IPC: A61K47/30
Filed: 1993-01-11
Abstract: Tablets of increased strength are manufactured by combining and compressing a meltable binder, excipients and a pharmaceutically active agent into a tablet, melting the binder in the tablet, and then solidifying the binder.
Patent PT-103724-A (PT)
Title: Chapa de ligação para uma corrente
Inventor: WU DANIEL
IPC: F16G15/14
Filed: 2007-04-23
Abstract: UMA CHAPA DE LIGAÇÃO (1) INTEGRANDO SUPERFÍCIES DOS LADOS DE DENTRO E DE FORA (12, 13), E UMA SUPERFÍCIE ENVOLVENTE INTERIOR (15) QUE DEFINE UM ORIFÍCIO DE RETENÇÃO (18) PARA ENCAIXE DE UMA PARTE TERMINAL DE RETENÇÃO (42) DE UMA CAVÍLHA DE LIGAÇÃO (4') . A SUPERFÍCIE ENVOLVENTE INTERIOR (15) É CONSTITUÍDA POR UMA ZONA DE MONTAGEM (151) LOCALIZADA EM REDOR DE UM PRIMEIRO PONTO CENTRAL (A), E POR UMA ZONA DE POSICIONAMENTO (152) LOCALIZADA EM REDOR DE UM SEGUNDO PONTO CENTRAL (B), E APRESENTA DUAS EXTREMIDADES AFASTADAS UMA DA OUTRA POR UMA DISTÂNCIA QUE É MAIS PEQUENADO QUE O DIÂMETRO (01) DA PARTE TERMINAL DE RETENÇÃO (42). UMA FLANGE (16) DESENVOLVE-SE A PARTIR DA ZONA DE POSICIONAMENTO (152), FICA ADJACENTE À SUPERFÍCIE DO LADO DE DENTRO (12) E MAIS AFASTADA RELATIVAMENTE À SUPERFÍCIE DO LADO DE FORA (13), POSSIBILITANDO QUE UM REBORDO (44) DA CAVILHA DE LIGAÇÃO (4') SE ENCOSTE DE ENCONTRO A ELA. DUAS REGIÕES SUPERFICIAIS PARA ESTABELECIMENTO DE COMUNICAÇÃO (171) FICAM COLOCADAS ENTRE A ZONA DE MONTAGEM (151) E AZONA DE POSICIONAMENTO (152), PARA DEFINIR URNA PASSAGEM QUE PERMITA A MOVIMENTAÇÃO DA PARTE TERMINAL DE RETENÇÃO (42) ENTRE A ZONA DE MONTAGEM (151) E A ZONA DE POSICIONAMENTO (152).
Patent PT-107653-A (PT)
Title: Elementos radiantes baseados em cavidades justapostas para uniformização térmica
Inventor: CONCEIÇÃO EUSÉBIO ZEFERINO ENCARNAÇÃO DA
IPC: F24D7/00
Filed: 2014-05-23
Abstract: A PRESENTE INVENÇÃO UTILIZA ELEMENTOS RADIANTES BASEADOS EM CAVIDADES, 7, JUSTAPOSTAS PARA UNIFORMIZAÇÃO TÉRMICA. É CONSTITUÍDA ATRAVÉS DE UMA BASE, 1, PAREDES ENVOLVENTES, 2, UM GRUPO DE PRISMAS TRIANGULARES, 4, E UM TOPO, 3, E EQUIPADA COM UM SISTEMA DE TRANSPORTE, 5, COM TRÊS CONFIGURAÇÕES, E VÁRIOS SISTEMAS DE RECIRCULAÇÃO, 6. O SISTEMA DE TRANSPORTE, 5, USADO NO FORNECIMENTO E NA REMOÇÃO DO FLUIDO, É CONSTRUÍDO ATRAVÉS DE TRÊS CONFIGURAÇÕES DE SISTEMA DE TRANSPORTE, 5, NOMEADAMENTE O SISTEMA DE TRANSPORTE, 5, RETILÍNEO, O SISTEMA DE TRANSPORTE, 5, CURVILÍNEO E O SISTEMA DE TRANSPORTE, 5, DE RETORNO. O FLUIDO ENTRA NUMA EXTREMIDADE DE UMA CAVIDADE, 7, DUM ELEMENTO, ATRAVÉS DO SISTEMA DE TRANSPORTE, 5, E SAI NA OUTRA EXTREMIDADE DUM ELEMENTO. A CIRCULAÇÃO DE FLUIDO, NO SISTEMA DE RECIRCULAÇÃO, 6, É GARANTIDA ATRAVÉS DA PASSAGEM DO FLUIDO NO SISTEMA DE TRANSPORTE, 5.
Patent RU-94011806-A (RU)
Inventor: KHROMENKO V V
IPC: A01G1/00
Filed: 1994-04-01
Abstract: FIELD: agriculture. SUBSTANCE: method involves forming vertical branches for fruit-bearing, with branches being selected of trees with crown, whose skeleton is composed of two horizontal and diametrical branches; removing vertical branches in 1-2 years and repeatedly forming vertical branches. Space between vertical branches is 15-20 cm. Height of vertical branches with fruit formations is 60-80 cm. Growth formations are annually pinched, when they reach 40-50 cm length, and completely removed after leaf fall. Method allows fruit-bearing zones to be formed at height not exceeding 1.3-1.5 m. EFFECT: increased efficiency in shaping single principle crown of different kinds of fruit trees, reduced cost, increased yield and improved quality of fruits. 3 cl, 1 tbl
Patent RU-94018375-A (RU)
Inventor: LIPNJAK L V
IPC: G01M3/00
Filed: 1994-05-19
Abstract: FIELD: testing. SUBSTANCE: invention is related to testing equipment and makes it possible to increase precision of test for tightness of pneumo-hydraulic systems, which aggregates and main lines are located both inside and outside of compartment of spacecraft. Spacecraft is positioned into vacuum chamber connected to leak detector. Volume of vacuum chamber is communicated with internal space of compartment. Vacuum chamber and compartment are pumped away by evacuation facilities up to ultimate residual pressure in vacuum chamber. Volume of vacuum chamber and internal space of compartment are separated. At same time firstly calibrated flow of test gas of specified value is fed into vacuum chamber, steady-state change of concentration of test gas in vacuum chamber from calibrated flow fed into vacuum chamber is measured and supply of calibrated flow of test gas of specified value into vacuum chamber is stopped and secondary similar calibrated flow of test gas is fed into compartment, delay is conducted in the course of accumulation time Tnecessary for positive measurement of maximum change of concentration of test gas in vacuum chamber from calibrated flow supplied into compartment after communication of volume of vacuum chamber with internal space of compartment, supply of calibrated flow of test gas of specified value into compartment is stopped, volume of vacuum chamber is communicated with internal space of compartment and maximum change of concentration of test gas in vacuum chamber from calibrated flow supplied into compartment is measured. Again volume of vacuum chamber and internal space of compartment are separated. Pneumo-hydraulic system is filled with test gas. At same time firstly steady state change of concentration of test gas in vacuum chamber caused by microleakages in aggregates and main lines of pneumo-hydraulic system located outside of compartment is measured and leak of outside part of pneumo-hydraulic system is found by relation of measured steady-state changes of concentrations of test gas in vacuum chamber and secondly delay is performed in the course of accumulation time T, test gas is relieved from pneumo-hydraulic system. Volume of vacuum chamber is again communicated with internal space of compartment, maximum change of concentration of test gas in vacuum chamber caused by microleakages in aggregates and main lines of pneumo-hydraulic system located inside compartment is measured and leak of internal part of pneumo-hydraulic system is determined by relation of measured maximum changes of concentrations of test gas in vacuum chamber. Leak of pneumo-hydraulic system is calculated as sum of leakages of its internal and external parts. EFFECT: increased precision of test for tightness of pneumo-hydraulic system. 1 cl
Patent RU-94025744-A (RU)
Inventor: BYKHOV V N
IPC: B29C47/02
Filed: 1994-07-11
Abstract: FIELD: processing of plastics, in particular, production of reinforced hoses and flat-rollable hoses. SUBSTANCE: device for production of hoses with a reinforcing casing of synoptic threads has an angle extrusion moulding head with moulding blocks and a guide bush having supports, each support represents a bar installed in the head body for reciprocating motion, floating core joined to the core foot through a movable joint, the working surface of the core through the reinforcing casing is engageable with the cylindrical surface of the retaining rollers. The movable joint is made in the form of two hemispheres secured on the bar ends, each hemisphere is conjugate to to the contact surface of washers installed on the front and rear ends of the foot and floating core respectively, and the support end is fastened to the central part of the strip having a lug on the ends, which enters the annular groove of the guide bush. EFFECT: improved quality due, to the equality of thickness of the hose and elimination of jamming of the floating core relative to the moulding block of the extrusion head.
Patent RU-94028194-A (RU)
Inventor: GEJN V L
IPC: A61P29/02
Filed: 1994-07-27
Abstract: FIELD: medicine. SUBSTANCE: desired product having formulais prepared by interaction of methyl ester of acetyl pyroracemic acid with glycol and with p-iodobenzaldehyde according to given scheme. Said process is carried out at room temperature. Yield of desired product is 71 %, its melting point being 288 C. EFFECT: increases analgetic activity of desired product, decreases its toxicity.
Patent RU-94030162-A (RU)
Inventor: IVASHNEV V K
IPC: A01G23/02
Filed: 1994-08-15
Abstract: FIELD: brush cutting units for land clearing machines. SUBSTANCE: brush cutting rotor has drive shaft with upper and lower disks and flat knives 5 mounted on pins between disks. Shaped disk 6 with peripheral stops 7 is fixed between disks, with stops being positioned at rear side of each knife 5. During working in normal operation mode at low loading (brush cutting), flat knives 5 are aligned under the action of centrifugal forces and rotate on their pins. In this case centrifugal forces and cutting forces are mutually balanced. When load is increased (tree trunk cutting), flat knives 5 are brought into contact with stops 7 of shaped disk 6 and rotor works in operation mode of cutter with fixed flat knives 5 to cut tree trunks. EFFECT: increased efficiency, wider operational capabilities and enhanced reliability in operation.