baber/WOPTO huggingface dataset:
Patent CA-3114164-A1 (CA)
Title: Systems and methods to enhance intake air flow to a gas turbine engine of a hydraulic fracturing unit
Inventor: YEUNG TONY
IPC: F02C7/055
Filed: 2021-04-06
Abstract: Systems and methods to increase intake air flow to a gas turbine engine of a hydraulic fracturing unit when positioned in an enclosure may include providing an intake expansion assembly to enhance intake air flow to the gas turbine engine. The intake expansion assembly may include an intake expansion wall defining a plurality of intake ports positioned to supply intake air to the gas turbine engine. The intake expansion assembly also may include one or more actuators connected to a main housing of the enclosure and the intake expansion assembly. The one or more actuators may be positioned to cause the intake expansion wall to move relative to the main housing between a first position preventing air flow through the plurality of intake ports and a second position providing air flow through the plurality of intake ports to an interior of the enclosure.
Patent CA-3114290-A1 (CA)
Inventor: RAZ SHARON
IPC: A23L33/15
Filed: 2019-11-04
Abstract: The present disclosure provides chewable tablets comprising (i) a compressed core including a bioactive molecule; (ii) a protective layer over said compressed core, and (iii) one or more soft-coating layers over said protective layer, each soft coating layer comprises gum base powder; wherein the protective layer comprises water-insoluble cellulose based polymers, preferably ethyl cellulose based polymer.
Patent CA-3115635-A1 (CA)
Inventor: NORRISH DAWSON
IPC: F25D11/00
Filed: 2021-04-20
Abstract: A mobile multizone refrigerator comprises a plurality of secure refrigerated storage zones each having a lockable door connected to a zone opening controller. The zone opening controller is connected by a network interface to a server capable of receiving and facilitating zone opening requests from the user devices of affiliated users of the storage zones. Upon receipt of an authenticated zone opening request, the server will transmit a zone opening instruction to the controller affiliated with the storage zone in question, resulting in its opening. The refrigerator is mobile allowing it to be moved into and between locations with ease.
Patent CA-3116521-A1 (CA)
Inventor: Malik Gurshaant Singh
IPC: G06N3/063
Filed: 2021-04-28
Abstract: Recurrent neural networks are efficiently mapped to hardware computation blocks specifically designed for Legendre Memory Unit (LMU) cells, Projected LSTM  cells, and Feed Forward cells. Iterative resource allocation algorithms are used to partition recurrent neural networks and time multiplex them onto a spatial distribution of computation blocks, guided by multivariable optimizations for power, performance, and accuracy.  Embodiments of the invention provide systems for low power, high perfomance deployment of recurrent neural networks for battery sensitive applications such as automatic speech recognition (ASR), keyword spotting (KWS), biomedical signal processing, and other applications that involve processing time-series data.
Patent CA-3117169-A1 (CA)
Title: Formes cristallines d'inhibiteurs de mnk
Inventor: REICH SIEGFRIED H
IPC: A61K31/713
Filed: 2019-10-23
Abstract: La présente invention concerne des solides cristallins de 6'-((6-aminopyrimidin-4-yl)amino)-8'-méthyl-2'H-spiro[cyclohexane-1,3'-imidazo[1,5-a]pyridine]-1,5'-dione Les composés cristallins de la présente invention sont des inhibiteurs de Mnk et trouvent une utilité dans un certain nombre d'applications thérapeutiques, comprenant, mais de façon non exhaustive, le traitement d'une inflammation et de divers cancers.
Patent CA-3117510-A1 (CA)
Title: 5-azaindazole derivatives as adenosine receptor antagonists
Inventor: BLAYO ANNE-LAURE
IPC: A61P35/00
Filed: 2019-10-22
Abstract: The present invention relates to novel 5-azaindazole derivatives of formula (I), as described and defined herein, and pharmaceutically acceptable salts, solvates and prodrug thereof, as well as pharmaceutical compositions comprising such compounds. The 5-azaindazole derivatives according to the invention have been found to be highly effective dual A2A/A2B adenosine receptor antagonists, and can thus be used as therapeutic agents, particularly in the treatment or prevention of hyperproliferative or infectious diseases or disorders.
Patent CA-3117657-A1 (CA)
Inventor: CHENG SHUJIANG
IPC: A61Q19/00
Filed: 2018-11-27
Abstract: L'invention concerne des compositions de soins personnels et des procédés servant à augmenter la production de facteurs d'hydratation naturels (FNH) et à augmenter la production de peptides antimicrobiens (PAM) dans la peau. Les compositions de soins personnels peuvent comprendre un support et une quantité efficace d'un ou de plusieurs polysaccharides sulfatés pour augmenter les FNH et les PAM dans la peau lorsqu'ils sont appliqués sur celle-ci.
Patent CA-3117761-A1 (CA)
Inventor: CHEN JIANWEN
IPC: A61K31/426
Filed: 2019-11-01
Abstract: The present disclosure relates to the joint use of compound A and compound B in the preparation of medications for the treatment of gout or hyperuricemia. Specifically, compound A is selected from the compound shown in Formula I, a pharmaceutical salt thereof, or an ester thereof, and compound B is selected from allopurinol or febuxostat. In particular, a method for treating gout or hyperuricemia in which the compound shown in Formula I-1 works in conjunction with febuxostat shows good treatment effect.
Patent CA-3117775-A1 (CA)
Inventor: VON GYNZ-REKOWSKI GUNTHER HH
IPC: E21B4/00
Filed: 2019-10-23
Abstract: A mud-lubricated bearing section including a seal assembly for directing a fluid flowing through a mud-lubricated bearing into a central bore of a mandrel. At least one mud- lubricated bearing is positioned in an annular space between the mandrel and a housing. The seal assembly directs the fluid from the annular space through a mandrel fluid port into the mandrel central bore. The seal assembly seals the annular space, and includes a piston, a plug, and a chamber between the piston and the plug. The piston is configured for axial movement relative to the mandrel and the housing, while the plug is axially fixed relative to the mandrel and/or the housing. The chamber is configured to contain a lubricating fluid. The piston includes inner and outer seals. The plug includes a lower seal and a passage allowing the fluid from the chamber to reach the lower seal for lubrication.
Patent CA-3118154-A1 (CA)
Inventor: BROOKER ANJU DEEPALI MASSEY
IPC: C11D11/00
Filed: 2019-11-21
Abstract: The present invention relates to a method for treating fabrics by contacting the fabrics with an aqueous wash liquor at varying pH values that increase from about 7-9 to about 10-13 (optionally down to about 7-9), maintaining such contact at pH 10-13 for about 5-30 minutes, followed by contacting the fabrics with an aqueous rinse liquor at an acid pH value of about 4-6. Such method provides a significantly improved stain removal benefit without any formulation changes. Further, it enables the use of laundry detergent compositions that are essentially free of alkoxylated surfactants, such as alkylalkoxylated sulfates or alkylalkoxylated alcohols, while still delivering satisfactory stain removal results.
Patent CA-3118201-A1 (CA)
Inventor: ROUSSET XAVIER
IPC: C12N5/09
Filed: 2019-10-29
Abstract: The invention relates to the use of an embryonated egg model grafted with tumor cells to study the anti-cancer effectiveness or screen immunotherapeutic molecules in the absence of immune effector cells other than those in the grafted egg.
Patent CA-3122621-A1 (CA)
Inventor: DUAN SHUWEN
IPC: C07D209/08
Filed: 2019-12-17
Abstract: Provided is an indole compound. In particular, disclosed are a compound represented by formula (II) or an isomer or pharmaceutically acceptable salt thereof and a use of the same as an estrogen receptor antagonist in preparing a drug for treating estrogen receptor-positive breast cancer. <img file="55081dest_path_image002.jpg" he="75.94" img-content="drawing" img-format="jpg" inline="yes" orientation="portrait" wi="108.74"/>
Patent CA-3127427-A1 (CA)
Title: Foot-based massage apparatus
Inventor: TSUKAYAMA DANIEL
IPC: A61H99/00
Filed: 2019-12-02
Abstract: A foot-based massage apparatus includes a base member having a first end portion and a second end portion opposite the first end portion. A top surface of the base member has a generally rectangular configuration. A first connector member is coupled to the first end portion, and a second connector member is coupled to the second end portion. A flexible member is coupled to the first connector member and the second connector member. When tension is applied to the flexible member, the flexible member supports a massage practitioner providing a foot-based massage. A first gripping member and a second gripping member are coupled to the base member. The first gripping member and the second gripping member restrict movement of the base member relative to a supporting surface.
Patent CA-3127517-A1 (CA)
Title: Membrane anode system for electrolytic zinc-nickel alloy deposition
Inventor: LEONHARD STEVEN
IPC: C25D21/18
Filed: 2020-01-22
Abstract: The present invention is related to a membrane anode system for electrolytic zinc-nickel alloy deposition, a method for electrolytic deposition of a zinc- nickel alloy layer on a substrate to be treated using a membrane anode system, and the use of a membrane anode system for acid or alkaline electrolytic deposition of a zinc-nickel alloy layer on a substrate to be treated by such a method.
Patent CA-3128299-A1 (CA)
Inventor: HENRIKSEN GEOFFREY
IPC: B23P19/10
Filed: 2021-08-13
Abstract: Methods and tools for facilitating the installation and/or removal of a rotor on a shaft of a gas turbine engine are provided. The tool includes a stabilizer attachable to the shaft and including a first guide counterpart. The tool also includes a holder attachable to the rotor and including a second guide counterpart for engagement with the first guide counterpart of the stabilizer. Engagement of the first and second guide counterparts guides movement of the holder relative to the stabilizer along a guide axis and prevents movement of the holder relative to the stabilizer transverse to the guide axis.
Patent CA-3130727-A1 (CA)
Inventor: BURNS CHRISTOPHER
IPC: C07D401/12
Filed: 2020-03-27
Abstract: The present invention is directed to the tartrate salt of a FAK inhibitor defined by formula (I) below, and the use of that inhibitor for treating a proliferative disease.
Patent CA-3131380-A1 (CA)
Inventor: MARTINEZ LORENA
IPC: B08B9/027
Filed: 2020-02-24
Abstract: A surface cleaning tool has a frame supporting a resiliently flexible panel supported by the frame in an arcuate configuration such that at least one of first and second opposite end portions of the resiliently flexible panel can be moved closer to the other end portion.
Patent CA-3132072-A1 (CA)
Title: Selection of t cell receptors
Inventor: DAVIS MATTHEW JOSEPH
IPC: G01N33/68
Filed: 2020-02-28
Abstract: Methods are provided to separately isolate antigen-binding T cells and antigen-activated T cells derived from a starting population of peripheral blood mononuclear cells, and to identify overlapping T cell receptor clonotypes. Antigens include personal and shared neoantigens as well as cancer-testis antigens. The T cell receptor clonotypes can be further used to develop cancer treatment therapies.
Patent CA-3133915-A1 (CA)
Title: Virtual object control method and apparatus, device, and storage medium
Inventor: CHEN YU
IPC: A63F13/55
Filed: 2021-03-01
Abstract: This application provides a virtual object control method and apparatus, a device, and a storage medium, and relates to the field of computer technologies. The method includes: displaying a virtual battle interface; obtaining a first operation signal corresponding to a function triggering control; and receiving a first trigger operation for the function triggering control, and determining a first virtual object in n virtual objects as an attack target based on operation information of the first trigger operation in response to the first trigger operation meeting an activation condition. Compared with the related art in which each time a target virtual object is determined in real time according to a virtual scene at the current time point, and target virtual objects determined in different virtual scenes may be different, according to the technical solutions provided in the embodiments of this application, an attack target is directly determined by using a target aiming function of a function triggering control and attribute information of an operation signal, thereby providing the attack target with directivity and stability for different virtual scenes.
Patent CA-3134127-A1 (CA)
Title: Sel d'addition d'acide de pyrimethamine
Inventor: KACZMAREK LUKAWSZ
IPC: A61K31/505
Filed: 2019-03-22
Abstract: L'invention concerne un sel d'addition d'acide de pyriméthamine (5-4-chlorophényl)-6-éthyl -2,4-pyrimidinediamine) et de l'acide méthane sulfonique, un procédé pour sa préparation et des compositions pharmaceutiques comprenant le sel d'addition d'acide.
Patent CA-3134171-A1 (CA)
Inventor: WANG YUGUANG
IPC: A61K31/429
Filed: 2020-03-20
Abstract: A small-molecule inhibitor of PD-1/PD-L1, a pharmaceutical composition thereof with a PD-L1 antibody, and an application of the same. The small-molecule inhibitor of PD-1/PD-L1 is aromatic ethylene or an aromatic ethylene derivative represented by general formula (I) and can be used to treat cancer.
Patent CA-3134234-A1 (CA)
Inventor: HOLMQUIST BRETT
IPC: G01N30/72
Filed: 2020-04-16
Abstract: Disclosed are methods, systems, and computer program products for using liquid chromatography/tandem mass spectrometry (LC-MS/MS) for the analysis of endogenous biomarkers, such as 11-oxo androgens, in a sample. The 11-oxo androgens may comprise at least one of 11-hydroxyandrostendione (11OHA), 11-hydroxytestosterone (11OHT) or 11-ketotestosterone (11KT). More specifically, the methods, systems, and computer program products are described for detecting and quantifying the amount of an 11-oxo-androgen in a sample.
Patent CA-3134601-A1 (CA)
Title: Produits biologiques a fc modifie pour administration locale a des compartiments, en particulier au snc
Inventor: VOM BERG JOHANNES
IPC: A61K38/20
Filed: 2020-03-27
Abstract: L'invention concerne un polypeptide comprenant une région de fragment (Fc) d'IgG cristallisable destinée à être utilisé dans la prévention ou le traitement d'une maladie, en particulier d'une maladie affectant le système nerveux central. Le polypeptide est administré localement à des compartiments, en particulier au système nerveux central. La région Fc comprend les mutations I253N et H435Q et un H en position 310 conférant une affinité réduite pour le récepteur Fc néonatal (FcRn), avec pour résultat un rapport de concentration cérébrale à sérique accrue du polypeptide.
Patent CA-3136105-A1 (CA)
Title: Continuous fanfolded joined corrugated
Inventor: MAGNELL GREGORY P
IPC: B32B29/08
Filed: 2020-03-24
Abstract: A bale of stock packaging material includes a continuous tube of paperboard material, the continuous tube of paperboard material being flattened and folded back and forth on itself into a fan-folded bale. The continuous tube of paperboard can be a single piece of paperboard with two opposed edges that are folded to overlap with each other. The paperboard material can include a corrugated layer. The opposed edges can be adhered together to form a single seam that runs lengthwise along the continuous tube of paperboard. The adhesive can be applied between the two edges which can join to form the single seam.
Patent CA-3139524-A1 (CA)
Inventor: LELLO RAYMOND
IPC: A01N43/653
Filed: 2020-05-07
Abstract: La présente invention concerne des combinaisons de composés actifs comprenant du fluopyram, au moins un fongicide (B) choisi dans le groupe des inhibiteurs de la chaîne respiratoire du complexe I ou II et au moins un autre fongicide (C) sélectionné dans le groupe d'inhibiteurs spécifiés de la chaîne respiratoire du complexe III, des compositions comprenant une telle combinaison de composés, et leur utilisation en tant qu'agents biologiquement actifs, en particulier pour lutter contre des micro-organismes nuisibles dans la protection des cultures et dans la protection de matériaux industriels.
Patent CA-3140345-A1 (CA)
Inventor: MENZEL JOHANNES
IPC: G01R31/00
Filed: 2021-11-24
Abstract: A method of analyzing events for an electrical system includes: receiving event stream(s) of events occurring in the electrical system, the events being identified from captured energy-related signals in the system; analyzing, an event stream(s) of the events to identify different actionable triggers therefrom, the different triggers including a scenario in which a group of events satisfies one or more predetermined triggering conditions; analyzing, over time, the different actionable triggers to identify a combination of occurring and/or non-occurring actionable triggers which satisfies a predefined trigger combination condition and an analysis time constraint; and in response to the observation of the combination, taking one or more actions to address the events. The analysis time constraint can be a time period duration and/or sequence within which time-stamped data of events in the event stream(s) and the associated actionable triggers are considered or not considered in the analysis to identify the combination.
Patent CA-3141608-A1 (CA)
Title: Rotatable infusion device and methods thereof
Inventor: ERICHSEN JESPER ORTLD
IPC: A61M39/02
Filed: 2020-05-19
Abstract: An infusion set that has a base having an opening to receive a cannula device, the base having a lower base part and an upper base part, wherein the upper base part is coupled to the lower base part and is rotatable relative to the lower base part and a connector that has a fluid connector tube. The connector prevents the upper base from substantially rotating relative to the lower base and the fluid connector tube is in fluid connection with the cannula device when the connector is coupled to the base.
Patent CA-3142382-A1 (CA)
Title: Device for manipulating preferably a casting tube in a changing device at the spout of a metallurgical vessel
Inventor: RENGGLI RAPHAEL
IPC: B22D41/60
Filed: 2020-06-26
Abstract: In the case of a device for manipulating preferably a casting tube (7) in a changing device (8) at the spout of a metallurgical vessel, this manipulation is performed by means of a robot (10). This robot has an attachable base (9), a carrying arm (12) that can pivot on the base and at least one extension arm (13) that is mounted rotatably on the carrying arm and has a gripper (14), preferably for the casting tube (7). The base (9) of the robot (10) is attached alongside the vessel in such a way that the carrying arm (12) can be pivoted to the side of the vessel into a downwardly directed position and the at least one extension arm (13) mounted on the carrying arm can be moved along the underside of the vessel. This provides optimum placement of the robot, and consequently of the device, and so they do not impede access for personnel to the tundish on the casting platform during casting and the corresponding manipulations, such as changing the casting tube, can be carried out very easily and operationally reliably with the device in an automated manner.
Patent CA-3145806-A1 (CA)
Inventor: NEVES LEANDRO GOMIDE
IPC: C12N15/09
Filed: 2020-05-13
Abstract: L'invention concerne des matériels et des méthodes de capture de régions génomiques cibles, comprenant le clivage de la région génomique cible à l'aide d'endonucléases au niveau de sites de reconnaissance spécifiques ayant un minimum d'environ 10 à environ 30 nucléotides et la capture de la région génomique cible par hybridation avec un oligonucléotide en pont. L'invention concerne également l'analyse des régions génomiques cibles capturées. Les endonucléases utilisées pour le clivage peuvent être des endonucléases programmables qui se lient spécifiquement aux sites de reconnaissance pour diriger le clivage. Les régions génomiques cibles capturées peuvent être amplifiées, de préférence, par réaction en chaîne de la polymérase ou amplification en cercle roulant et détectées ou séquencées. En outre, l'invention concerne des kits permettant de mettre en uvre les méthodes selon l'invention, comprenant une ou plusieurs endonucléases conçues pour cliver une ou plusieurs régions génomiques cibles et des oligonucléotides en pont conçus pour capturer la ou les régions génomiques cibles. Les kits peuvent être personnalisés pour des régions génomiques cibles spécifiques.
Patent CA-3146682-A1 (CA)
Title: Procede et appareil d'entrelacement automatique de charges cyclees dans un micro-reseau
Inventor: ZIMMANCK DONALD RICHARD
IPC: H02J3/14
Filed: 2020-07-29
Abstract: L'invention concerne un procédé et un appareil d'entrelacement automatique et autonome de charges cyclées couplées à un réseau. Dans un ou plusieurs modes de réalisation, le procédé comprend (i) la détermination, par une charge intelligente couplée à un réseau, d'une première valeur de contrainte de réseau; (ii) la comparaison, par la charge intelligente, de la première valeur de contrainte de réseau à un seuil d'activation; (iii) l'attente, par la charge intelligente, lorsque la première valeur de contrainte de réseau est inférieure au seuil d'activation, d'une période de retard; (iv) la détermination, par la charge intelligente et après la fin de la période de retard, d'une seconde valeur de contrainte de réseau; (v) la comparaison, par la charge intelligente, de la seconde valeur de contrainte de réseau au seuil d'activation; et (iv) l'activation, par la charge intelligente, lorsque la seconde valeur de contrainte de réseau est inférieure au seuil d'activation.
Patent CA-3147424-A1 (CA)
Title: Modified host cells for high efficiency production of vanillin
Inventor: RAETZ LAUREN
IPC: C12N15/52
Filed: 2020-07-31
Abstract: Provided herein are genetically modified host cells, compositions, and methods for improved production of vanillin and/or glucovanillin. The host cells, compositions, and methods described herein provide an efficient route for the heterologous production of vanillin and/or glucovanillin and any compound that can be synthesized or biosynthesized from either or both.
Patent CA-3152674-A1 (CA)
Title: Derives de pyrazole pour l'inhibiteur des fgfr et methode de preparation connexe
Inventor: ZHENG QIANGANG
IPC: A61K31/496
Filed: 2020-08-28
Abstract: La présente invention concerne un composé amide pyrazole utilisé en tant qu'inhibiteur irréversible de FGFR, son procédé de préparation et son utilisation. Spécifiquement, la présente invention concerne un composé de formule I, ou un sel pharmaceutiquement acceptable de celui-ci, ou un solvate de celui-ci, un substituant isotopique, un promédicament, ou un métabolite. Le composé de formule I a une activité inhibitrice de FGFR, et peut prévenir ou traiter des troubles liés à l'activité de FGFR ou une quantité d'expression, telle que, de préférence, le cancer.