baber/WOPTO huggingface dataset:
Patent AU-2019203652-A1 (AU)
Title: Calibrating nanopore capture rates using controlled counting
Inventor: BRIGGS KYLE
IPC: G01N27/447
Filed: 2019-05-24
Abstract: Attorney Docket No. 15265-000025-US 
ABSTRACT 
Methods for determining molecular concentration using solid-state nanopores are 
provided. The methods include measuring a current signal and using the signal to 
identify first and second electrical signatures. A first set is used to determine a first 
rate of a target having an unknown concentration, and a second set is used to 
determine a second rate of a control having a known concentration. The first and 
second rates are each a function of a pore property factor that represents physical 
properties of the solid-state nanopore and operating conditions. The first rate is 
further a function of a first property factor that represents physical properties of the 
target and the unknown concentration. The second rate is further a function of a 
second property factor that represents physical properties of the control and the 
known concentration. Ratios of the first rate to the second rate are used to 
determine the unknown concentration.  
23260824.2 
39
Attorney Docket No.: 15265-000025-US 
9/15 
800 
812 810 
812 812 
810 
802 806 
804/ 
FIG. 8
Patent AU-2019214347-A1 (AU)
Title: Glass formulations comprising steroid dimers and uses thereof
Inventor: PARRAG IAN CHARLES
IPC: A61L27/54
Filed: 2019-02-01
Abstract: Steroid dimers and articles formed from steroid dimers are disclosed. Said steroid dimers are represented by D1-L-D2 wherein D1 and D2 are steroid moieties and L is a covalent linker. The articles comprising the steroid dimers can be machined, molded, emulsion-processed, electrospun, electrosprayed, blow molded, fiber spun, wet spun, dry spun, melt spun, heat spun, gel spun, or extruded to form a fiber, fiber mesh, woven fabric, non-woven fabric, pellet, cylinder, microparticle, nanoparticle, or shaped article. Said articles are used as drug delivery devices (e.g. an implant) for the extended delivery of a steroid to a subject.
Patent AU-2019221568-A1 (AU)
Title: Pyridine derivatives and their use for treating HIV infection
Inventor: BRIZGYS GEDIMINAS
IPC: A61P31/18
Filed: 2019-02-14
Abstract: The invention provides compounds having Formula (I): (I) or a pharmaceutically acceptable salt thereof, as well as pharmaceutical compositions comprising the same, processes for their preparation, and methods of treating and preventing HIV infection by their administration.
Patent AU-2019229361-A1 (AU)
Title: Input count rate estimation in radiation pulse detectors
Inventor: PAULEY MICHAEL
IPC: H03K5/00
Filed: 2019-09-11
Abstract: The invention provides a method of estimating an input count rate of a radiation pulse detector. In a calibration mode, the method comprises (a) calculating a known function of the input count rate parameter derived from the detector signal sampled over the calibration period; (b) estimating a calibration input count rate during the calibration period using a chosen input count rate estimation method applied to the detector signal sampled over the calibration period known to be reliable at the estimated calibration input count rate; and (c) determining a calibration function relating measurements of the parameter to the input count rate based on the calculated parameter over the calibration period, the calibration input count rate during the calibration period and the known function. In an operation mode, the method comprises (d) calculating the parameter derived from the detector signal over a measurement period; and (e) estimating the input count rate during the measurement period by applying the calibration function to the parameter derived from the detector signal over the measurement period. 4-4 ~0 t
Patent AU-2019235033-A1 (AU)
Title: Anti-claudin 18.2 antibodies
Inventor: SONG YUNTAO
IPC: A61K39/395
Filed: 2019-03-14
Abstract: Provided are anti-claudin 18.2 (CLDN18.2) antibodies and fragments thereof. Also provided are isolated nucleic acid molecules that encode anti-CLDN18.2 antibodies, vectors comprising such nucleic acid, and host cells comprising such vectors or nucleic acids. Provided are methods of making anti-CLDN18.2. Also provided are related pharmaceutical compositions and methods using such pharmaceutical compositions in the treatment of disorders associated with aberrant CLDN18.2 expression, such as cancers.
Patent AU-2019253562-A1 (AU)
Title: Methods and compositions comprising a viral vector for expression of a transgene and an effector
Inventor: POWELL DANIEL J
IPC: A61K48/00
Filed: 2019-04-08
Abstract: The present invention relates to compositions and methods comprising a single viral vector comprising both a first polynucleotide comprising a constitutive promoter operably linked to a nucleic acid encoding at least one transgene, wherein one of the at least one transgenes encodes a receptor or receptor subunit, a receptor fusion protein or a fluorescent marker; and a second polynucleotide comprising an inducible promoter operably linked to a nucleic acid encoding an effector. Also provided are engineered cells comprising the viral vector and methods for generating the engineered cells comprising the viral vector. Further provided are methods for treating a patient having a disease, a disorder or a condition associated with expression of an antigen, the method comprising administering to the patient an effective amount of a composition comprising the engineered cell.
Patent AU-2019253868-A1 (AU)
Title: Device for the provision of bone cement
Inventor: VOGT SEBASTIAN
IPC: A61M5/24
Filed: 2019-10-24
Abstract: DEVICE FOR THE PROVISION OF BONE CEMENT The invention relates to a device (100) for the provision of a bone cement (322) made of two starting components, comprising a hollow cylinder-shaped first container (200), in which a monomer liquid (211) as first starting component can be stored; a hollow cylinder-shaped second container (300) comprising a container wall (310), a first internal space (320), and a second internal space (330); whereby a bone cement powder (321) as second starting component can be stored in the first internal space (320); and whereby the monomer liquid (211) can be conveyed into the second internal space (330); a fluid-conducting conveying means (340) arranged between the first internal space (320) and the second internal space (330); whereby the first container (200) and the second container (300) are axially connected to each other; wherein a dispensing plunger (400) that can be axially shifted in the second container (300) and is arranged between the first container (200) and the second internal space (300); whereby the dispensing plunger (400) acts in concert appropriately with the container wall (310) such that, in a first position of the dispensing plunger (400), the first container (200) and the second internal space (330) are connected in monomer liquid (211)-conducting manner; and, in a first position of the dispensing plunger (400), the first container (200) and the second internal space (330) are connected in monomer liquid (211)-non-conducting manner. Fig. 1 Fig. 1
Patent AU-2019282560-A1 (AU)
Title: Process for synthesis and purification of (2R,6R)-hydroxynorketamine
Inventor: THOMAS CRAIG J
IPC: C07C225/20
Filed: 2019-06-04
Abstract: A process for the preparation of (
Patent AU-2019286163-A1 (AU)
Title: Filtration system and method for filtering water
Inventor: HEIJNEN MARTIN
IPC: B01D61/18
Filed: 2019-05-29
Abstract: The invention relates to filtration system (20), comprising a tank (40) filled at least partly with water to be filtered, and at least one filtration module (30), the at least one filtration module (30) comprising at least one filter membrane (10) for filtering the water comprising a substrate (12) which is penetrated by at least one capillary (16), and at least one filtrate pipe (32) for drawing filtered water out of the tank (40), whereat the at least one filtration module (30) is arranged in the tank (40) such that the at least one filter membrane (10) is submerged at least partly in the water to be filtered. The at least one filtration module (30) is designed and arranged such that water to be filtered flows into the at least one capillary (16) and from the at least one capillary (16) through the substrate (12) into the filtrate pipe (32). The invention also relates to a method for filtering water by means of a filtration system (20) according to the invention, whereat the water to be filtered is drawn into the at least one capillary (16) and from the at least one capillary (16) through the substrate (12) into the filtrate pipe (32) and from the filtrate pipe (32) out of the tank (40).
Patent AU-2019295902-A1 (AU)
Title: Light treatment system
Inventor: BINNER CURT
IPC: A61N5/06
Filed: 2019-06-28
Abstract: A phototherapy system wearable on a portion of a user's face includes a lamp platform and a controller unit disposed on, and electrically coupled to, the lamp platform, and a frame for holding the lamp platform in a fixed orientation on a user's face. The controller unit has an inwardly facing surface directed toward the user's face during use; a rechargeable power source; and a charging receptacle disposed in the inwardly facing surface and in electrical communication with the charging receptacle. In use, the frame holds the lamp platform and controller unit in a relationship such that the spacing between the charging receptacle and a closest surface of the user's face defines a charging receptacle clearance.
Patent AU-2019320981-A1 (AU)
Title: Method for operating a microwave device
Inventor: DE ANGELIS ANDREA
IPC: H05B6/68
Filed: 2019-07-17
Abstract: The invention relates to a for operating a microwave device (1), the microwave device (1) comprising a cavity (2) and multiple microwave modules (3) for providing microwaves into said cavity (2), the method comprising the steps of: - providing multiple sets of operation parameters, each set of operation parameters being associated with a certain microwave module (3); • simultaneously transmitting the sets of operation parameters to the respective microwave modules (3) and synchronously applying the set of operation parameters within the respective microwave module (3) after receipt of said set of operation parameters; or • uploading the sets of operation parameters to the respective microwave modules (3) and applying the set of parameters within the respective microwave module (3) after receipt of an acknowledge command or after expiry of a certain time period.
Patent AU-2019322292-A1 (AU)
Title: Modified Y molecular sieve, catalytic cracking catalyst containing same, and preparation therefor and application thereof
Inventor: ZHOU LINGPING
IPC: C10G11/05
Filed: 2019-08-15
Abstract: A modified Y molecular sieve, the preparation method therefor, a catalytic cracking catalyst, and the application thereof. In the modified Y molecular sieve, the rare earth content calculated on the basis of oxides is 4-11wt%, and the content of P calculated on the basis of P
Patent AU-2019326067-A1 (AU)
Title: Domain-based isolated mailboxes
Inventor: THIRUMAVALAVAN VIRUTHAGIRI
IPC: G06Q10/10
Filed: 2019-08-19
Abstract: Systems and methods are provided for reducing email spam without wasting network bandwidth. The system contains two groups of boxes. Domboxes and Mailboxes. (a) Domboxes should be used only for non-conversational mails. E.g. website/app mails. Each Dombox has a disposable email address and associated with a primary domain. The primary domain can authorize additional domains in the DNS. We primarily rely on the SPF record for validating Dombox mails. (b) Mailboxes are designed to accept only conversational mails. Conversational Mails can be termed as Human-to-Human, Mailbox-to-Mailbox or MX-to-MX mails. We pull the MX record from the Envelope Domain and verify whether it's really originating from one of the MX servers. Spammer is a Human. Since we accept only MX record verified mails, spammers need registered domains to send spam. Additional checks can be performed with the help of Domain registration date, Spam Filters, Challenge/Response etc.
Patent AU-2019337699-A1 (AU)
Title: Small highly uniform nanomedicine compositions for therapeutic, imaging and theranostic applications
Inventor: HOPKINS THOMAS
IPC: A61K49/00
Filed: 2019-09-13
Abstract: A targetable nanoconstruct capable of simultaneously serving as a therapeutic platform for photodynamic therapy as well as an MR molecular imaging agent, free of heavy metal atoms. F3-cys targeting agent nanoconstructs, including 8PEGA-Ce6 NCs. A label-free 8PEGA nanoconstruct that can be directly and selectively imaged by MRI, using standard spin-echo imaging sequences with large diffusion magnetic field gradients to suppress the water signal.
Patent AU-2019340838-A1 (AU)
Title: Automated generation and analysis of organoids
Inventor: BRUDER JAN MARKUS
IPC: C12N5/0797
Filed: 2019-09-11
Abstract: The present invention relates to a method of producing organoids, said method comprising or consisting of: (a) seeding a plurality of tissue-specific precursor cells into a container; (b) allowing to occur (i) aggregation of said cells; and (ii) maturation of the aggregate formed in (i) into a single organoid; wherein said method does not comprise embedding of said cells or said aggregates into a gel.
Patent AU-2019351820-A1 (AU)
Title: Small molecule menin inhibitors
Inventor: WANG SHAOMENG
IPC: A61P35/00
Filed: 2019-09-30
Abstract: The present disclosure provides compounds represented by Formula I: and the pharmaceutically acceptable salts and solvates thereof, wherein R
Patent AU-2019357597-A1 (AU)
Title: Dissolvable composition having indicia
Inventor: KAISERMAN TERRANCE
IPC: B65D85/808
Filed: 2019-10-10
Abstract: The invention is directed to compositions and methods for preparing dissolvable compositions. The dissolvable compositions include a plurality of dissolvable layers, where the dissolvable layers convey a message when associated with a solvent.
Patent AU-2019377422-A1 (AU)
Title: Treatment of NSCLC patients refractory for anti-PD-1 antibody
Inventor: FARDIS MARIA
IPC: A61P35/00
Filed: 2019-11-04
Abstract: The present invention provides improved and/or shortened processes and methods for preparing TILs in order to prepare therapeutic populations of TILs with increased therapeutic efficacy for the treatment of non-small cell lung carcinoma (NSCLC), wherein the NSCLC is refractory to treatment with an anti-PD-1 antibody.
Patent AU-2019390969-A1 (AU)
Title: Double stranded oligonucleotide construct comprising androgen receptor specific sequence, and composition for preventing hair loss and promoting hair growth comprising same
Inventor: PARK HAN-OH
IPC: A61K47/54
Filed: 2019-11-18
Abstract: The present invention relates to: a double stranded oligonucleotide construct having a structure of the form in which a hydrophilic material and a hydrophobic material are conjugated by a simple covalent bond or a linker-mediated covalent bond at both ends of a double stranded oligonucleotide in order to efficiently deliver an androgen receptor specific oligonucleotide into a cell; a nanoparticle which can be produced by self-assembling the double stranded oligonucleotide constructs in an aqueous solution by hydrophobic interaction; and a composition for preventing hair loss or for promoting hair growth comprising the double stranded oligonucleotide construct. The double stranded oligonucleotide construct comprising an androgen receptor specific oligonucleotide, and the composition for preventing hair loss or for promoting hair growth comprising the same as an active ingredient, according to the present invention, can inhibit the expression of an androgen receptor with high efficiency without side effects, and thus can have an excellent effect on the prevention of hair loss, especially androgenic hair loss, alopecia areata, and telogen alopecia and the promotion of hair growth.
Patent AU-2019457235-A1 (AU)
Title: Method for preparing long-acting drug conjugate through preparation of novel intermediate
Inventor: SHIN CHEONGBYEOL
IPC: C07K14/575
Filed: 2019-07-18
Abstract: The present invention relates to a novel method for preparing a long-acting drug conjugate, and a long-acting drug conjugate prepared by the method.
Patent AU-2019462198-A1 (AU)
Title: Polymer material and method for producing same
Inventor: Rastorguev Dmitrii Sergeevich
IPC: B32B27/00
Filed: 2019-09-17
Abstract: A polymer material consists of expanded polyethylene terephthalate with a density of 30 kg/m3 to 750 kg/m3 and an intrinsic viscosity of 0.5 dl/g to 1.0 dl/g. Polyethylene terephthalate granules with an intrinsic viscosity ranging from 0.5 dl/g to 1.0 dl/g which are produced from polyethylene terephthalate waste products or virgin polyethylene terephthalate are dried to a moisture content of 50 to 7000 ppm, then loaded into a dosing hopper of an extruder where said material is mixed with dyes or processing aids. The polyethylene terephthalate is then extruded while simultaneously feeding nitrogen or carbon dioxide or isopentane or n-pentane or freon or mixtures thereof into a connector upstream of the die. In the die and at the outlet from the die, temperature- and pressure-controllable expansion of the polyethylene terephthalate melt is carried out to a density ranging from 30 kg/m3 to 750 kg/m3. The melt from the die is fed onto calender rolls where said melt is cooled and calendered to a thickness of 500 to 25,000 μm, and then scored (creased) and cut into separate sheets. The result achieved is moisture resistance and a high recycling rate.
Patent AU-2019477159-A1 (AU)
Title: Drilling fluid measurements using active gas dilution
Inventor: ROWE MATHEW DENNIS
IPC: E21B49/00
Filed: 2019-12-03
Abstract: Aspects and features include a system and method for drilling fluid measurement using active gas dilution. Active and automatic correction of the flow of a mixture of a sample gas and a carrier gas supplied to detectors is used while making measurements. A computing device measures a physical state of the mixture, determines a gas flow rate for the mixture, and determines a corrected flow rate for the carrier gas based on the physical state of the mixture and the mixture gas flow rate. The computing device then adjusts the flow rate of the carrier gas into the drilling fluid to maintain the corrected flow rate. This control improves accuracy by reducing the introduction of contaminants from the measurement environment and allowing compositional measurement to be made well above the lower detection limits of the detectors being used for the measurements.
Patent WO-2021003517-A1 (WO)
Title: Derivatives of 4-(imidazo[l,2-a]pyridin-3-yl)-n-(pyridinyl)pyrimidin- 2-amine as therapeutic agents
Inventor: WANG SHUDONG
IPC: A61P35/00
Filed: 2020-07-10
Abstract: A novel class of heteroaryl compounds for use in the prevention and/or treatment of proliferative diseases and conditions including cancers. The compounds are considered to be capable of inhibiting cell proliferation by inhibiting the activity of FLT3 and its mutant forms and/or other protein kinases such as CDKs. The compounds have the general structure I:
Patent WO-2020150789-A1 (WO)
Inventor: HUBER THOMAS
IPC: C12N15/52
Filed: 2020-01-24
Abstract: Provided herein are encapsulated cells that comprise a microbial cell modified to express a cytolytic enzyme and encapsulated with one or more layers of a cationic polymer and one or more layers of an anionic polymer that may be used in cell-free protein synthesis. To this end, methods of utilizing such encapsulated cells in synthesizing a target protein, degrading a contaminant in a contaminated environment and detecting an analyte in a sample are also disclosed herein. Further provided herein, are methods of producing such encapsulated cells.
Patent WO-2021056078-A1 (WO)
Inventor: REDFERN DAVID
IPC: C02F1/68
Filed: 2020-09-26
Abstract: The invention provides methods for treating or disrupting biofilm in wastewater systems comprising the step of adding to the system at least one biofilm disrupting dose of one or more compounds of general formula I: R-O-O-R 1  I wherein, R is selected from C 1 -C 8  alkyl, substituted C 1 -C 8  alkyl, aryl, substituted aryl, C 1 -C 8  acyl, substituted C 1 -C 8  acyl, arylacyl and substituted arylacyl; and R 1  is selected from H, M + , C 1 -C 8  alkyl, substituted C 1 -C 8  alkyl, aryl, substituted aryl, C 1 -C 8  acyl, substituted C 1 -C 8  acyl, arylacyl and substituted arylacyl.
Patent AU-2020203253-A1 (AU)
Title: Systems and method for digital radio broadcast with cross platform reception
Inventor: MILBAR MAREK
IPC: H04H20/86
Filed: 2020-05-19
Abstract: Systems and methods are described for rendering content at a digital radio broadcast receiver system. A digital radio broadcast signal comprises data for rendering content at the digital radio broadcast receiver. The digital radio broadcast signal is processed to determine whether the data from the digital radio broadcast transmission contains a data error. A portion of the data containing the data error is identified. A download request is transmitted to a computing system, where the download request requests duplicate data for the portion of the data containing the data error. The duplicate data is received at the digital radio broadcast receiver for the portion of the data containing the error via other wireless communication other than the digital radio broadcast. The duplicate data is processed to provide an uninterrupted rendering of the content. H:\Interwoven\NRPortbl\DCC\AKW\20222525_1.DCCX - 19/5/20
Patent AU-2020204193-A1 (AU)
Title: Mobile communication system, base station and user equipment
Inventor: MAEDA MIHO
IPC: H04W72/04
Filed: 2020-06-24
Abstract: A mobile communication system includes a user equipment and a base station. The user 
equipment and the base station interactively communicate through an aggregated carrier 
5 having a plurality of component carriers. The base station transmits component-carrier 
information to the user equipment or the user equipment transmits the component-carrier 
information to the base station, when transmission or reception is performed between the 
user equipment and the base station. The component-carrier information indicates the 
information relates to which component carrier among the plurality of component 
10 carriers.
Patent AU-2020205779-A1 (AU)
Title: Glasses temple assembly and glasses
Inventor: YANG YUFENG
IPC: G02C5/14
Filed: 2020-01-08
Abstract: Disclosed is a glasses temple assembly, comprising a glasses temple main body (12), a guide member (13), a first temple core (14), a second temple core (15), a first pivot (16), and a second pivot (17), wherein the second temple core (15) is elastically connected to the glasses temple main body (12) and is configured for providing an elastic force transmitted in a lengthwise direction of the glasses temple main body (12); the guide member (13) is sheathed on the periphery of the first temple core (14), and the first temple core (14) comprises a first connecting end (141) and a second connecting end (142) arranged oppositely; the second connecting end (142) is pivoted to the second temple core (15) via the second pivot (17), and the first connecting end (141) is pivoted to an end piece (110) of a spectacle frame (11) or a glasses temple front hinge (18) via the first pivot (16); the first pivot (16) and the second pivot (17) are perpendicular to each other; and the guide member (13) elastically abuts against the glasses temple main body (12). When a glasses temple is subjected to loads in horizontal and vertical directions, elastic bending or swinging in different directions is generated at a front end and a rear end of the guide member (13), respectively, the situation in which elastic swinging is generated in four directions at the same part of a glasses frame (10) resulting in the feeling of random shaking is avoided, and the user experience on 360-degree rotation of the glasses temple is better.