baber/WOPTO huggingface dataset:
Patent SG-173116-A1 (SG)
Title: Aroylamino - and heteroaroylamino-substituted piperidines as glyt-1 inhibitors
Inventor: KOLCZEWSKI SABINE
Filed: 2010-01-19
Abstract: The present invention relates to a compound of general formula (I) wherein R1 is hydrogen, lower alkyl, CD3, -(CH2)n-CHO, -(CH2)n-O-lower alkyl, -(CH2)n-OH, -(CH2)n-cycloalkyl or is heterocycloalkyl; R2 is hydrogen, halogen, hydroxy, lower alkyl, di-lower alkyl, -OCH2-O-lower alkyl, or lower alkoxy; or the piperidin ring form together with R2 a spiro ring, selected from 4-aza-spiro[2.5]oct-6-yl; Ar is aryl or heteroaryl, which are optionally substituted by one, two or three substituents, selected from halogen, lower alkyl, lower alkyl substituted by halogen, lower alkoxy substituted by halogen, cycloalkyl, lower alkoxy, S-lower alkyl, heteroaryl, heterocycloalkyl, or by phenyl optionally substituted by R', and R' is halogen, lower alkyl, lower alkoxy or lower alkoxy substituted by halogen, or is heteroaryl; R is lower alkyl, cycloalkyl, heterocycloalkyl, aryl or heteroaryl, wherein aryl and heteroaryl are optionally substituted by one or two R'; n is 0, 1 2 or 3; or to a pharmaceutically acceptable acid addition salt, to a racemic mixture, or to its corresponding enantiomer and/or optical isomer thereof. Furthermore, the present invention relates to pharmaceutical compositions containing the compounds of formula I and to their use in the treatment of neurological and neuropsychiatric disorders.
Patent SG-175695-A1 (SG)
Title: Pulse-modulated high-frequency power control method and pulse-modulated high-frequency power source device
Inventor: YUZURIHARA ITSUO
Filed: 2010-03-05
Abstract: Abstract of the DisclosureIn a pulse power control, power amplitude (peak power) of output power is controlled to be constant against the fluctuation of the power, whereby it is possible to avoid aneffect on a load, which is caused by the fluctuation of the power amplitude of the output power. The pulse modulated RF power control method includes an output amplitude control step for controlling amplitude of a pulse output, and a duty control step for controlling a duty ratio of the pulse output. The outputamplitude control step performs a constant amplitude control to control an amplitude value of the pulse output so that the amplitude value becomes equal to a set amplitude value. The constant amplitude control according to the output amplitude control, for instance, gives a feedback of the amplitude valueof the pulse output outputted by the power control, obtains a difference value between the feedback value and the set amplitude value, and controls the amplitude value of the pulse output so that the difference value becomes zero.
Patent SG-174483-A1 (SG)
Title: Use of artemisinin derivatives for the treatment of asthma and chronic obstructive pulmonary disease (copd)
Inventor: WONG WAI SHIU FRED
Filed: 2010-03-24
Abstract: Artesunate is a derivative of artemisinin isolated from a Chinese herb Artemisia annuaL. It is used clinically for the treatment of malaria. We investigated potential anti-inflammatory actions of artemisinin derivatives. artemisinin derivatives significantly inhibited OVA-induced signs, symptoms and parameter of airway disorders Taken together, our results clearly demonstrate anti-inflammatory effects of artemisinin derivatives. Artemisinin derivatives can be used to complement or to replace oral steroids during asthma exacerbation treatment. Further artemisinin derivatives can be used as an anti-inflammatory agent for controlling airway disorders.
Patent SG-174991-A1 (SG)
Title: Isolation of human umbilical cord blood-derived mesenchymal stem cells
Inventor: CHEN XIAO-DONG
Filed: 2009-06-19
Abstract: Human umbilical cord blood (UCB) contains mesenchymal stem cells (MSCs) that have higher multipotentiality than adult marrow-derived MSCs. However, it has been difficult to obtain these cells because the frequency of MSCs in UCB is extremely rare (0.4 - 30 out of 1 X 108 mononuclear cells). To date, the isolation of MSCs has depended upon their plastic-adhesion capacity. Some "true" MSCs could be missed because their ability to adhere to plastic may be poor. Previous studies demonstrated extracellular matrix (ECM) made by bone marrow cells enhanced MSC attachment and proliferation, and retained their stem cell properties. The present invention provides methods for isolating MSCs from umbilical cord blood by adherence to an ECM and uses for the isolated stem cells.
Patent SG-175131-A1 (SG)
Title: Therapeutic applications in the cardiovascular field of quinazolinedione derivatives
Inventor: JANIAK PHILIP
Filed: 2010-04-07
Abstract: 159THERAPEUTIC APPLICATIONS OF QUINAZOLINEDIONE DERIVATIVES AbstractA subject-matter of the present invention is the use of compounds of formula (I) (I)in the base, hydrate or solvate form or in the form of their mixtures, as medicaments or for the preparation of medicaments intended for the treatment of at least one cardiovascular disease and/or to prevent the appearance of at least one cardiovascular disease.
Patent SG-175661-A1 (SG)
Title: Fluidized bed method and reactor for carrying out exothermic chemical equilibrium reactions
Inventor: SOHN MARTIN
IPC: B01J8/24
Filed: 2005-03-21
Abstract: FLUIDIZED BED METHOD AND REACTOR FOR CARRYING OUT EXOTHERMIC CHEMICAL EQUILIBRIUM REACTIONSAbstractThe invention relates to a process for carrying out exothermic chemical equilib rium reactions in a fluidized-bed reactor, wherein there is a temperature distribu tion in the fluidized bed of the fluidized-bed reactor and the temperature differencebetween the lowest temperature and the highest temperature is at least 10 K. The invention further relates to a fluidized-bed reactor for carrying out chemical reac tions In a fluidized bed (5), wherein at least one heat exchanger (12, 28) is located in the fluidized bed (5) to control the temperature distribution.(Figure 1)
Patent WO-2013089647-A1 (WO)
Title: Binding molecules against dengue virus and uses thereof
Inventor: FINK KATJA
IPC: C07K16/08
Filed: 2012-12-17
Abstract: The present invention relates to binding molecules suited to the diagnosis, prevention and/or treatment of dengue virus infection.
Patent SG-178731-A1 (SG)
Title: Prevention of liner choke-off in liner-based pressure dispensation system
Inventor: CISEWSKI MICHAEL A
IPC: B67D7/72
Filed: 2008-01-30
Abstract: To avoid problems associated with choke-off of a collapsible liner (e.g., disposed within a rigid overpack) during pressure dispensing of fluid therefrom, a pressure dispense package includes a choke prevention element comprising any of a perforated flange within the liner, a channel-defining flange within the liner, a film defining at least one liquid channel along an inner surface of the liner, a radial stiffening element coupled to the liner, an orifice-defining hollow internal support disposed within the liner, one or more magnetic and complementary magnetically responsive elements associated with the liner and surrounding container, or differential collapse characteristics between liner panels. Methods for preventing choke-off of a collapsible liner adapted for pressure dispensing are also provided.Figure 1
Patent SG-186740-A1 (SG)
Title: Self limiting catalyst composition for ethylene polymerization
Inventor: JORGENSEN ROBERT JAMES
Filed: 2011-06-29
Abstract: A process for polymerizing ethylene to produce an ethylene -based polymer including contacting ethylene with a Ziegler-Natta procatalyst, an alkylaluminum cocatalyst and a self limiting agent selected from the group of aliphatic, cycloaliphatic, substituted cycloaliphatic or aromatic esters, anhydrides and amides such that the self limiting agent reduces polymerization rates to no greater than 40% of the polymerization rate in the absence of the self limiting agent at temperatures equal to or greater than 120 °C is provided.
Patent WO-2013122541-A1 (WO)
Title: Mécanisme de liaison et de libération de munitions
Inventor: AW CHENG HOCK
IPC: F42B39/10
Filed: 2013-02-07
Abstract: L'invention concerne un dispositif de couplage destiné à relier et à libérer des balles/cartouches sur une bande de munitions formée par une chaine à maillons, chacun des maillons supportant une balle/cartouche. Chaque maillon comprend un trou en poire et un connecteur, le dispositif de couplage comprend une paire de porte-balles venant en butée l'un contre l'autre le long du côté longitudinal dudit dispositif de couplage, les deux porte-balles coulissent l'un contre l'autre le long du côté longitudinal, les porte-balles sont conçus avec un évidement destiné à retenir chacun une balle et un canal destiné à recevoir le connecteur et le trou en poire. Eventuellement, lorsque les deux porte-balles ont coulissé pour déconnecter le connecteur du trou en poire, la balle est libérée.
Patent WO-2013137827-A1 (WO)
Inventor: WANG XIN
IPC: C01B32/949
Filed: 2013-03-13
Abstract: La présente invention concerne un procédé de synthèse de nanotiges de carbure de tungstène, le procédé consistant à : mélanger des nanotiges d'oxyde de tungstène (WO 3 ) avec une source de carbone pour obtenir des précurseurs ; et calciner les précurseurs pour obtenir des nanotiges de carbure de tungstène, sans utiliser aucun catalyseur. L'invention concerne également un catalyseur constitué de nanostructures de métal supportées sur des nanotiges de carbure de tungstène.
Patent SG-188216-A1 (SG)
Title: Process for separating and recovering metals
Inventor: BHADURI RAHUL SHANKAR
Filed: 2011-08-10
Abstract: A process for treating spent catalyst containing heavy metals, e.g., Group VIB metals and Group VIII metals is provided. In one embodiment after deoiling, the spent catalyst is treated with an ammonia leach solution under conditions sufficient to dissolve the group VIB metal and the Group VIII metal into the leaching solution, forming a leach slurry. After solid-liquid separation to recover a leach solution, chemical precipitation and solids repulping is carried out to obtain an effluent stream containing ammonium sulfate (Amsul), ammonium sulfamate, Group VB, Group VIB and Group VIII metals. Following sulfidation, the Group VIII metal is fully removed and Group VB and Group VI metals are partially removed from the Amsul stream. In the additional steps of oxydrolysis and iron precipitation, an effective amount of ferric ion at a pre-select pH is added to form insoluble complexes with the Group VB and Group VIB metals, which upon liquid-solid separation produces an effluent ammonium sulfate stream containing less than 10 ppm each of the Group VB and Group VIB metals.
Patent SG-188441-A1 (SG)
Title: Device for removably fixing a current conductor to a current transformer housing
Inventor: LEIFER CHRISTOPH
Filed: 2011-10-07
Abstract: The invention relates to a device for removably fixing a current conductor (1) to a current transformer housing (2), comprising the current transformer housing (2), a retaining element (3) which is led through the current transformer housing (2), a fixing element (4) which is led through the retaining element (3), and a clamping element (5), said fixing element (4) and/or retaining element (3) at least partly sitting against the surface of the current conductor (1) in a fixed state of the current conductor (1) to the current transformer housing (2). The fixing element (4) is rotatable about the fixing element longitudinal axis in a rotary manner in order to fix or remove the current conductor (1), and the clamping element (5) is arranged in a movable manner on the current transformer housing (2) such that the clamping element (5) allows a translational movement of the retaining element (3) along the retaining element longitudinal axis in order to fix or remove the current conductor (1) in a first position and prevents the translational movement of the retaining element (3) along the retaining element longitudinal axis in order to remove the current conductor (1) in a second position. As a result, the device according to the invention thus allows a particularly simple and quick fixing of a current conductor (1) to a current transformer housing (2).
Patent SG-189880-A1 (SG)
Title: Cyclosporin analogs
Inventor: CARLING WILLIAM ROBERT
Filed: 2011-10-11
Abstract: Disclosed herein are novel analogs of cyclosporin, pharmaceutical compositions containing them, and methods for their use in the treatment of dry eye and other conditions.
Patent SG-190244-A1 (SG)
Title: Methods of treating cancer
Inventor: REDDY JOSEPH ANAND
IPC: A61K33/243
Filed: 2011-11-11
Abstract: Described are methods and compositions for treating epithelial tumors with a folate-vinca conjugate in combination with at least one other chemotherapeutic agent in which the tumors include ovarian, endometrial or non-small cell lung cancer tumors, including platinum-resistant ovarian tumors and platinum-sensitive ovarian tumors.
Patent SG-192232-A1 (SG)
Title: Guided transfer car system
Inventor: FUJIOKA SHINJI
Filed: 2011-12-06
Abstract: GUIDED TRANSFER CAR SYSTEMIn a rail guided vehicle system, unnecessary slowing down and stopping of a vehicle passing through a divergence point and a merge point is avoided. The rail guided vehicle system comprises a rail 100 including a guidepath wire 600 in a predetermined area including5 the divergence point and the merge point, and a plurality of vehicles 200 that travel while being supported and guided by the rail. Each of the plurality of vehicles includes a generating unit 910, 920 configured to generate each of a plurality of signals each having different frequencies from the others, a transmitting unit 810, 820 configured to send each of the plurality of signals generated by the generating unit to the guidepath wire, a receiving unit10 710, 720 configured to receive each of the plurality of signals transmitted via the guidepath wire, a determining unit 955 configured to determine, based on the kind of the signal received by the receiving unit, whether the vehicle is slowed down, stopped, or kept travelling, and a controlling unit 960 configured to control the vehicle in accordance with a result of a determination determined by the determining unit.15Figure 7
Patent WO-2021118458-A1 (WO)
Inventor: LEONG YONG SHIN
IPC: G06T19/00
Filed: 2020-12-01
Abstract: A method comprising identifying a robotic device and a calibration fixture in a vicinity of the robotic device; referencing the calibration fixture to a base of the robotic device to determine a first pose of the robotic device; receiving a 3D image of the environment, wherein the 3D image includes the calibration fixture; determining a second pose of the calibration fixture relative to the sensor; determining a third pose of the robotic device relative to the sensor based on the first pose and the second pose; receiving a plurality of trajectory points; determining a plurality of virtual trajectory points corresponding to the plurality of trajectory points based on the 3D image and the third pose; providing for display of the plurality of virtual trajectory points; and providing an interface for manipulating the virtual trajectory points.
Patent WO-2010104480-A1 (WO)
Title: Système et procédure pour l'estimation d'état psychologique basée sur des réactions psychophysiologiques et transmission de l'état estimé sur divers réseaux
Inventor: MATJAZ MIHELJ
IPC: A61B5/16
Filed: 2009-10-14
Abstract: La présente invention concerne un système pour l'estimation d'état psychologique basée sur des réactions psychophysiologiques et la transmission de l'état estimé sur divers réseaux. Le système et la procédure pour l'estimation d'état psychologique basée sur des réactions psychophysiologiques et la transmission de l'état estimé sur divers réseaux est constitué d'un sous-système de mesure (1), qui comporte des anneaux avec des capteurs pour la photopléthysmographie, la température de conductivité cutanée (21, 22, 23, 24), un bracelet (3), des connexions (41, 42, 43, 44), une ceinture avec des capteurs ECG et de respiration (5), un microphone, une caméra, des codeurs (K1-K6) et des émetteurs sans fil (01-06). Le système comporte également un récepteur sans fil (6) connecté à un sous-système informatique (7). Le sous-système informatique (7) assure le stockage continu des signaux provenant de l'émetteur sans fil (6) en mémoire et sur le lecteur de disque dur. Des signaux, en mémoire, sont filtrés par le sous-système informatique et utilisés pour calculer les paramètres psychophysiologiques nécessaires à l'estimation de l'état psychologique. Le système permet à l'utilisateur de choisir parmi différents algorithmes pour l'estimation de l'état psychologique. Il est conçu de manière modulaire de sorte que différents capteurs peuvent être ajoutés ou enlevés. L'estimation de l'état psychologique peut être transmise vers un site différent sur divers réseaux.
Patent TN-2009000034-A1 (TN)
Title: Smac peptidomimetics useful as iap inhibitors
Inventor: CHAREST MARK G
IPC: C07K5/06
Filed: 2009-01-30
Abstract: The present invention is directed to a compound of the formula (1); or pharmaceutically acceptable salts thereof and use of such compounds for treating proliferative diseases such as cancer, in mammals.
Patent TN-2009000086-A1 (TN)
Title: New fluorene derivatives, compositions containing the same and use thereof as inhibitors of the protein chaperone hsp 90
Inventor: THOMPSON FABIENNE
IPC: C07D519/00
Filed: 2009-03-13
Abstract: The invention relates to new products of the formula (I) in which: Het is an optionally substituted mono- or bicyclic heterocycle containing 1 to 4 heteroatoms selected from N, O or S; R1 is X-(A-B)n-CONH2, X-(A¬B)n-O-CONH2, X-(A-B)n-NH-CONH2, X-(CH2)m-heterocycloalkyl, X-(CH2)m-aryl and X-(CH2)m¬heteroaryl with X being -O-C(O), -NH-C(O), NH-CS, -NH-CO-CH2-O-; -NH-CO-CH2-S-CH2-CO-NH-; -NH¬CO-(CH2)2-SO2-; -NH-CO-CH2-N(CH3)-CO-; A and B represent a simple bond, CH2, CH-alkyl, CH¬aralkyl, n = 1,2 and m = 0, 1; R2 and R'2 represent H, halogen, CF3, nitro, cyano, alkyl, hydroxy, mercapto, amino, alkylamino, dialkylamino, alkoxy, alkylthio, carboxy free or esterified by an alkyl, carboxamide, CO-NH(alkyl) and NH-CO-alkyl radical; p= 1 to 4 and p'= 1 to 3; L represents a simple bond, CH2, C(O), O, S or NH, all said radicals being optionally substituted. The invention also relates to all the isomeric forms of the products and the salts thereof used as drugs.
Patent TN-2010000425-A1 (TN)
Title: Procede et unite de transformation de betteraves
Inventor: TIERNY JEAN-BENOIT
Filed: 2010-09-17
Abstract: L'invention concerne un procédé de transformation de betteraves comprenant au moins les étapes suivantes : lavage des betteraves; pressage partiel des betteraves pour l'obtention d'une part, d'un gâteau de pressage sucré à plus de 20% par rapport à la matière sèche et, d'autre part, d'un jus sucré à une concentration supérieure à 15% de matière sèche; séparation du gâteau de pressage et du jus sucré. L'invention concerne également des nutritions pour animaux, des substrats de fermentation et du sucre alimentaire à base des produits obtenus à partir de ce procédé de transformation de betteraves.
Patent TN-2011000170-A1 (TN)
Title: Use of dithiin tetracarboximides for treating phytopathogenic fungi
Inventor: SEITZ THOMAS
IPC: A01P3/00
Filed: 2011-04-12
Abstract: The present invention relates to the use of novel and known dithiin tetracarboximides for treating phytopathogenic fungi, and to a method for treating phytopathogenic fungi for pest management, and pest management agents comprising said dithiin tetracarboximides.
Patent TN-2012000258-A1 (TN)
Title: Novel polymorphic shapes of methyl{4,6-diamino-2-[1-(2-fluorobenzyl)-1h-pyrazolo[3,4-b]pyridine-3-yl]pyrimidin-5-yl)carbamate
Inventor: GRUNENBERG ALFONS
IPC: C07D471/04
Filed: 2012-05-24
Abstract: The invention relates to novel shapes of methyl{4,6-diamino-2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-B]pyridine-3-yl]pyrimidin-5-yl)carbamate of the formula (I), in particular the modification I, to a method for the production thereof, to medications comprising same, and to the use thereof for treating illnesses.
Patent TN-2012000305-A1 (TN)
Title: Method for producing homopolysaccharides
Inventor: Therre Jörg
IPC: C12P19/04
Filed: 2012-06-15
Abstract: The invention relates to a method for producing aqueous solutions of glucanes having a main chain having ß-1,3-glycosidic bonds, and side groups bonded thereto by ß-1,6-glycosidic bonds, by fermenting fungus strains secreting said glucanes into the fermentation broth in an aqueous culture medium, wherein the separating of the glucanes from the fermentation broth takes place by means of asymmetric filter membranes.
Patent TN-2018000405-A1 (TN)
Title: Prototype de production d'énergie électrique à base d'énergie solaire et éolienne avec capture du vent et augmentation de sa vitesse.
Inventor: GUIDARA ZIED
IPC: F03D9/00
Filed: 2018-11-27
Abstract: Le but de la présente invention est de proposer un prototype pour la production de l'énergie électrique à base d'énergies renouvelables et propres : solaire et éolienne. Ce but est atteint en se basant sur la production électrique à travers deux technologies : des panneaux photovoltaïques selon une inclinaison permettant la bonne capture de l'ensoleillement solaire et une éolienne fonctionnant sous une vitesse de vent amplifiée suite à un système basé sur une succession de canalisations subissant des réductions de leurs diamètres.. Ainsi, ce prototype comporte principalement ces composants : des panneaux photovoltaïques, un système éolien, un boitier, des plaques supports à inclinaison réglable, un système de capture du vent, un système d'amplification de la vitesse du vent, un système de stockage énergétique et un support porteur.
Patent WO-2014193321-A1 (WO)
Title: Lock system for a plane seat dining table
Inventor: GUNER AYKUT
IPC: B60N3/00
Filed: 2014-04-02
Abstract: A lock system comprising a main frame (1), a handle pin (3) extended within said main frame (1), a handle (4) connected to one end of said handle pin (3) in such manner to have freedom of movement around its axis, and a spring (2) placed around the idle tip section of the handle pin (3) in the backrest section in such manner to surround the handle pin (3) in order to keep said handle (4) fixed at designated position, characterized in comprising a handle pin release (3.2) provided in the section of the handle pin (3) where spring (2) is placed, and at least one spring disassembly release (2.1) which enables the spring (2) to release from said handle pin release (3.2) by being structured in such manner to enable external intervention to the spring (2) on the main frame (1).
Patent WO-2020130976-A1 (WO)
Inventor: YÜCE EMRE
IPC: G01S7/481
Filed: 2019-12-06
Abstract: The invention is related to a system which enables to develop a LIDAR application by means of the rotation of optical elements that have been embedded on a rotating disk in a spherical geometry, which also enables to conduct the fastest possible spatial scanning mechanically and to determine the flight times of these light beams by means of adaptive elements according to the distance and size of the target region.
Patent WO-2022019854-A1 (WO)
Inventor: CAMLICA FAHRI BUGRA
IPC: B64C9/00
Filed: 2021-04-15
Abstract: La présente invention concerne un corps (2) situé dans un véhicule aérien et/ou spatial, au moins une surface de commande (3) qui est située sur le corps (2) et qui se déplace par rapport au corps (2), permet à l'écoulement d'air d'être commandé et au véhicule aérien de manœuvrer en conséquence, au moins un actionneur (4) qui est constitué d'un matériau polymère électroactif, est situé sur le corps (2) et change sa forme en fonction de l'énergie électrique et, grâce à cela, déclenche la surface de commande (3).