baber/WOPTO huggingface dataset:
Patent CA-2123307-A1 (CA)
Title: Process for the preparation of transferrin receptor specific antibody-neuro-pharmaceutical or diagnostic agent conjugates
Inventor: FRIDEN PHILLIP M
IPC: C07K16/28
Filed: 1992-11-24
Abstract: The present invention pertains to a method for delivering a neuropharmaceutical or diagnostic agent across the blood brain barrier to the brain of a host. The method comprises administering to the host a therapeutically effective amount of an antibody-neuropharmaceutical or diagnostic agent conjugate wherein the antibody is reactive with a transferrin receptor and the antibody is a chimera between the variable region from one animal source and the constant region from a different animal source. Other aspects of this invention include a delivery system comprising an antibody reactive with a transferrin receptor linked to a neuropharmaceutical or diganostic agent and methods for treating hosts afflicted with a disease associated with a neurological disorder. In embodiments of the present invention, the antibody that is reactive with a tranferrin receptor is a chimeric antibody. This antibody is composed of a variable region, immunologically reactive with the transferrin receptor, that is delivered from one animal source and a constant region that is derived from an animal source other than the one which provided the variable region. The chimeric antibodies of this invention can exist either as isolated entities or as conjugates with a neuropharmaceutical agent for transferal across the blood brain barrier. In the latter mode, the chimeric antibody-neuropharmaceutical agent conjugate forms a delivery system for delivering the neuropharmaceutical agent across the blood brain barrier.
Patent CA-2126766-A1 (CA)
Title: Transmission output shaft drive assembly
Inventor: BRAUN EUGENE R
IPC: F16H37/00
Filed: 1994-06-27
Abstract: TRANSMISSION OUTPUT SHAFT DRIVE ASSEMBLY                      Abstract An improved multiple speed gear transmission output shaft drive arrangement includes a synchronizer mounted  for  rotation  with  the  output  shaft,  an internally toothed range gear coaxial with and rotatable relative to the output shaft and auxiliary countershaft assemblies  including  externally  toothed  auxiliary countershaft gears constantly meshed with the internally toothed range gear for driving engagement thereby.
Patent CA-2126811-A1 (CA)
Title: Method and apparatus for analysis of polyphase electrical motor systems
Inventor: LEON ROBERT L
IPC: G01R31/34
Filed: 1994-06-27
Abstract: METHOD AND APPARATUS FOR ANALYSIS OF POLYPHASE ELECTRICAL MOTORS     Abstract A method for determining at least one operating parameter to determine the operating condition of a polyphase electric motor system comprises sensing the instantaneous current signal and the instantaneous voltage signal as a function of time for more than one electrical phase of the motor.  The sensed current signals and the sensed voltage signals are both amplitude demodulated and phase demodulated to provide amplitude demodulated current and voltage signals as a function of time and phase demodulated current and voltage signals as a function of time.  The resulting amplitude and phase demodulated signals are used to determine one or more of the following electrical parameters as a function of time:  total real power, real power per phase, total reactive power, reactive power per phase, total apparent power, apparent power per phase, overall power factor, power factor per phase, electrical impedance per phase, and electrical balance.
Patent CA-2126962-A1 (CA)
Inventor: BLONDEL ERIK
IPC: G06F8/65
Filed: 1994-06-28
Abstract: A method for updating a system program in a switching equipment. Many known, program-controlled switching equipment have a system program deposited in read-only memories. For modifying the system program, a replacement of the read-only memories is necessary, as known. The method updates the system program without having to undertake interventions in the existing switching equipment. Proceeding from a data processing device, administration and maintenance orders are communicated to the administration and maintenance interface of the existing switching equipment, these administration and maintenance orders being misused for the purpose of transmitting an updated system program stored in the data processing device into the switching equipment and in order to reroute the program processing of the system processor located in the switching equipment onto the newly written system program.
Patent CA-2129990-A1 (CA)
Inventor: OHTA MITSUAKI
IPC: C07D243/34
Filed: 1993-02-26
Abstract: A benzodiazepine derivative of formula (1), or a pharmaceutically acceptable salt thereof, wherein (a) R1 is -CH2CHOH(CH2)a R4 or a ketone group -CH2CO(CH2)a R5 in which a is 0 or 1 and R4 and R5 are selected from alkyl and cycloalkyl groups and saturated heterocyclic groups optionally substituted at a hetero-atom; (b) R2 and R3 are independently selected frown aromatic carbocyclic and heterocylic residues; and (c) W and X  are selected independently from halogen and hydrogen atoms and alkyl and alkoxy groups. These compounds are gastrin and/or CCK-B receptor antagonists.
Patent CA-2130689-A1 (CA)
Inventor: INOUE AKIO
IPC: G11B19/04
Filed: 1994-08-23
Abstract: A data write apparatus includes a card conveyor path, a recording head, a sensor circuit, a CPU, a drive circuit, and an enable section.  A magnetic card is conveyed in the card conveyor path.  The recording head is arranged on the card conveyor path and performs a recording operation on the magnetic card by energizing a winding coil.  The sensor circuit is arranged on the card conveyor path near the recording head and detects the magnetic card conveyed in the card convey path to output a detection signal.  The CPU outputs write data to be written on the magnetic card in response to the detection signal from the sensor circuit.  The drive circuit energizes the winding coil of the recording head on the basis of the write data from the CPU to perform the recording operation.  The enable section enables the drive circuit for a predetermined time after the write data is output from the CPU to limit energization for the winding coil of the magnetic head to a time equal to or shorter than the predetermined time.
Patent CA-2134001-A1 (CA)
Title: Method for the hot-end coating of hollow glass objects
Inventor: EISEN HEINZ-GUENTER
IPC: C07F7/22
Filed: 1994-10-21
Abstract: ABSTRACT OF THE DISCLOSURE           A method is described for the hot-end costing of hollow-glass objects by the application of tin compounds, optionally dissolved in organic solvents, on the surface of hollow glass objects heated to 500° to 600°C, the tin compounds being pyrolyzedwith the formation of thin tin oxide layers.  For this method, monobutyl tin tricarboxylates, which can be dissolved in organic solvents having a boiling point below 180°C, are vapor deposited on the glass surfaces.
Patent CA-2135172-A1 (CA)
Title: Process for the temporary consolidation of ballast
Inventor: IHLE CLAUSDIETER
IPC: E01B1/00
Filed: 1993-05-05
Abstract: A b s t r a c t The process for the temporary consolidation of railroad track ballast, in particular during the time of redevelopment or re-construction of a parallel set of tracks, is performed in that the ballast is cemented partially in particular in the side area by a multi component adhesive, wherein this cementation may be broken up mechanically later without affecting reuse of the ballast.
Patent CA-2146895-A1 (CA)
Title: Ctla4/cd28ig hybrid fusion proteins
Inventor: LINSLEY PETER S
IPC: C07K19/00
Filed: 1995-04-12
Abstract: ABSTRACT OF THE INVENTION          The invention identifies the CTLA4 receptor as a ligand for the B7 antigen.  The complete amino acid sequence encoding human CTLA4 receptor gene is provided. Methods are provided for expressing CTLA4 as an immunoglobulin fusion protein, for preparing hybrid CTLA4 fusion proteins, and for using the soluble fusion proteins, fragments and derivatives thereof, including monoclonal antibodies reactive with B7 and CTLA4, to regulate T cell interactions and immune responses mediated by such interactions.
Patent CA-2147124-A1 (CA)
Title: Erythropoietin analogs
Inventor: ELLIOTT STEVEN G
IPC: C12N5/10
Filed: 1994-08-16
Abstract: Erythropoietin analogs having at least one additional site for glycosylation, or a rearrangement of at least one site for glycosylation are disclosed. The invention also relates to DNA sequences encoding said erythropoietin analogs, and recombinant plasmids and host cells for analog expression.
Patent CA-2147928-A1 (CA)
Title: Switchable Circuit Breaker
Inventor: MOALEM FRED
IPC: H01H71/54
Filed: 1995-04-26
Abstract: A switchable circuit breaker having a housing, stationary and moveable contacts, a switching member for actuating the contacts to assume a first condition in which the contacts are open and a second condition in which the contacts are closed, and a breaker member disposed within the housing to interrupt current flow through the contacts in response to said current flow exceeding a predetermined level.      The switching member includes a pusher moveable between an advanced position in which the pusher acts on the contacts to assume a contact opening condition and a retracted position in which the pusher releases the contacts to assume a contact closing position. The pusher is guided within the housing so as to convert a linear motion of its drive end into a step-like motion of its active end in order to provide a snapping transition between said closing and opening conditions of the contacts, thus assuring "non-tease-ability" in the switching operation.
Patent CA-2147940-A1 (CA)
Inventor: VAN KUIJEREN HERMAN CORNELIS P
IPC: B21B13/02
Filed: 1995-04-26
Abstract: Apparatus and method for manufacture of DR          (Double Rolled) steel strip in which a continuous annealing furnace is arranged for annealing of cold-reduced steel strip passing continuously through said furnace, and a rolling mill for cold-rolling of steel strip is arranged to receive in-line the output of annealed steel strip from said furnace. The mill has at least one roll stand having a pair of work rolls of which only one is driven externally.  Rolling fluid, preferably free of mineral oil, is supplied to the strip being rolled in the rolling mill, and is removed from the strip prior to entry of the strip to downstream tension-applying means.
Patent CA-2149978-A1 (CA)
Inventor: MCALISTER STEVEN A
IPC: B04B1/00
Filed: 1995-05-23
Abstract: A centrifugal concentrator for separating higher density particles from a slurry provides reduced water consumption by providing a fluidized capture zone in the upper section of the bowl only,  and provides an unob-structed interior migration surface in the lower part of the bowl to provide a preliminary separation of heavier particles.
Patent CA-2152864-A1 (CA)
Inventor: NERI GIUSEPPE
IPC: B44D3/08
Filed: 1995-06-28
Abstract: The present invention relates to an apparatus for mixing liquid products, in particular to prepare coloring substances for paints and the like. the apparatus includes a base supporting a substantially horizontal table with supports, on the top face thereof, a plurality of vessels for the liquid products to be mixed. Inside each vessel is applied a stirring element which projects by its driving end portion from the vessel. The apparatus further includes a coupling element for coupling the driving end portions of the stirring elements to a driving device which can be actuated to simultaneously drive the stirring elements.
Patent CA-2155576-A1 (CA)
Inventor: MIKANIKIAN FARAMARZ
IPC: A01D7/10
Filed: 1995-08-08
Abstract: An auxiliary grabbing head is attached to the spreader bar of a conventional garden rake by means of two hinges. Two torsional coil springs, retract the grabbing head in to an upright position, at all time during normal raking and storage. When the rod linking the upper cylindrical sleeve to the grabbing mechanism is pulled upward a clamp formes, producing a strong grip on the leaves and grass pile to be lifted in to disposal, thus making the lawn work much easier and less time consuming.
Patent CA-2158379-A1 (CA)
Title: Stay on tab end with bead on tear panel to enable wide contact with tab to enhance propagation of score line rupture
Inventor: CLARKE MILTON W III
IPC: B65D17/32
Filed: 1995-09-15
Abstract: An easy-open construction for a container wherein a panel principally defined by a rupturable score line in a wall is opened by operating a tab having one end adapted to press against the panel at a position spaced from the score line and overlying only a small portion of the opening left by the panel in its open position.  The other end of the tab is liftable to open the panel and is returned directly to its original position next to the wall.  The tab and panel remain secured to the wall after the panel has been moved to its open position.  To ensure complete rupturing of the score line, particularly during initial rupturing past the 3:00 position, a bead is formed to extend beneath the tab to create a point of contact between the bead with the tab which is located towards the 3:00 position of the score line relative to another point of contact between the tab with the tear panel located further away from the 3:00 position. This another point of contact acts as a fulcrum for the first mentioned point of contact to generate a shearing force to propagate the rupture.
Patent CA-2160138-A1 (CA)
Title: Lithium ferrite carrier
Inventor: SUKOVICH ALAN
IPC: G03G9/113
Filed: 1994-04-07
Abstract: A non-stoichiometric lithium ferrite powder having a compositional range represented by the formula:  [(Li2O).25 (Fe2O3).25]x (Fe2O3)1.00-x where .35  x  .50 mole percent, provides an environmentally safe carrier.
Patent CA-2162539-A1 (CA)
Inventor: MIRANDA NATHANIEL R
IPC: C08L23/16
Filed: 1995-11-09
Abstract: A composite film and vacuum skin package for packaging a product such as a fresh red meat is disclosed. The composite film is thermoformed and sealed under vacuum to a support member to completely enclose a product which is positioned on the support member. The composite film is a permeable film weakly bonded to an impermeable film, permitting the impermeable film to be peeled from the package while leaving the permeable film intact so that the fresh red meat product can bloom from a purplish color to a desirable red color upon exposure to oxygen. The permeable and impermeable films are fully peelable without the need for a migratable wax to enhance peelability.
Patent CA-2165463-A1 (CA)
Inventor: MCGLINCH TIMOTHY M
IPC: A61B19/02
Filed: 1994-06-24
Abstract: A storage container (10) for catheters (30) having a separable portion (17) of the front wall (11) detachable from the container (10) to ease removal of the catheter (30) from the container (10) is disclosed. The top portion is preferably separated from the side walls (12, 13) along external score lines (20a, b) at the intersection of the front (11) and side walls (12, 13). The separable portion (17) of the front wall (11) is preferably hinged on the bottom edge, which is perforated, easing complete separation of the separable portion (17) from the front wall (11). Internal score lines (21a, b) on the inside surface of the separable portion (17) of the front wall (11), parallel and proximate the external score lines (20a, b) are preferably provided to form flaps (19) when the top portion of the front wall (11) is detached from the container (10). The flaps (19) prevent the top of the catheter package from falling out of the container (10). The separable portion of the front wall (11) enables the catheter (30) to be easily removed from the storage container (10) without it being damaged.
Patent CA-2167001-A1 (CA)
Inventor: HASKELL BARIN GEOFFRY
IPC: H04N21/6373
Filed: 1996-01-11
Abstract: Encoder/decoder buffer overflow and underflow encountered when employing actually variable or effectively variable bit-rate channels for communicating encoded video images and corresponding audio signals are overcome by adjusting the parameters of a video encoder in response to a representation of cell delay variation, i.e., jitter, determined at a remote decoder.
Patent CA-2170203-A1 (CA)
Title: Method of securing members together and fastener therefor
Inventor: BREWER JONATHAN LEE
IPC: F16B19/08
Filed: 1996-02-23
Abstract: A fastener comprises a pin having a head 14 and swaging grooves 16 on its shank, together with a collar 12 which is swaged into the groove 16 to lock the collar to the pin and thereby secure together two metal sheets 23, 24. The underhead face of the pin head is formed with a projecting annular rib 28. When the pin head is urged towards the adjacent sheet 24 during the fastener installation process, the rib 28 enters the sheet 24 and engages therewith. This enhances resistance to relative slipping of the sheet 24 with respect to the pin and the other sheet 23, thereby enabling the use of an oversize hole 26 in the sheet 24. The collar 12 may alternatively or additionally be provided with a similar rib 29 for a similar purpose.
Patent CA-2171149-A1 (CA)
Title: Reduced dusting bath system for continuous metallurgical treatment of sulfide materials
Inventor: MARCUSON SAMUEL WALTON
IPC: F27D27/00
Filed: 1996-03-06
Abstract: A pyrometallurgical vessel suitable for continuous or semicontinuous smpelting and/or conversion of molten base metal sulfide feed materials. The top blown, bottom stirred vessel includes oxidizing gas lances and feed pipes directing their respective contents directly or indirectly into bath eyes opened up in the molten bath by gas injected through porous plugs disposed at the base of the vessel. Low space velocities in the vessel result in reduced dusting.
Patent CA-2173203-A1 (CA)
Inventor: ANASTOS WILLIAM N
IPC: F04B49/02
Filed: 1993-10-04
Abstract: Un système (10) de commande de démarrage de pompe à régime réduit destiné à commander un moteur de pompe comprend un dispositif de commutation destiné à alimenter le moteur en énergie, un générateur (18) de cycle de marche périodique destiné à actionner périodiquement le dispositif de commutation à une fraction du cycle de marche complet afin de faire fonctionner la pompe à un régime réduit, plus silencieux, un capteur (16) destiné à capter le courant prélevé par le moteur (12) de la pompe, un circuit de référence (28) ainsi qu'un détecteur (24) de liquide destiné à détecter la présence du liquide à pomper, réagissant au capteur et au circuit de référence, afin d'outrepasser le générateur de cycle de marche périodique et d'actionner le dispositif de commutation pour faire fonctionner le moteur de la pompe continûment à pleine puissance lorsque le courant absorbé par le moteur dépasse un niveau prédéterminé indiquant la présence de liquide.
Patent CA-2175843-A1 (CA)
Title: Capillary sampling flow controller
Inventor: SIMON PHILIPPE
IPC: G01N1/24
Filed: 1996-05-06
Abstract: A capillary sampling flow controller provides an improvement in the process of sampling or monitoring for the analysis of air and gas chemistries; a constant flow rate is used to introduce a specific volume of gas into a vessel or through a trapping media over the selected sampling period. The improvement employs calculated geometry of the capillaries employed to deliver the gas sample to the evacuated vessel. It can also include a pressure reading device installed between the vessel and the capillary, and a filter at the inlet. The length of capillary with available internal diameters is estimated mathematically and confirmed experimentally to achieve any sampling time using any size sampler.  The flow rate obtained from the controller is constant over its operating range and is designed to meet a specific sampling duration to obtain long-term integrated samples. The sampling process becomes completely passive, precise, reliable and simple to operate.
Patent CA-2178958-A1 (CA)
Title: Optical information recording medium and method for producing same
Inventor: SAWADA KAZUMI
IPC: G11B7/2534
Filed: 1995-10-25
Abstract: The present invention is relative to an optical information recording medium having a reflective layer for reading out information signals by an optical technique. The optical information recording medium is formed as a plastic substrate.      According to the present invention, the substrate is colored by admixture of a dyestuff for enabling instant judgment by the visual sense of the operator as to the contents of the optical information recording medium, for example, as to if the contents of the recording medium is a game program or the music information. If impurities such as dyestuffs are admixed, the optical system of the readout device is usually affected thus raising readout difficulties. Such ill effects on the optical system may be eliminated by setting the particle size of the dyestuff so as to be 50 µm or less.
Patent CA-2179381-A1 (CA)
Inventor: SHIH JESSIE W
IPC: G01N33/569
Filed: 1994-12-20
Abstract: Procédés de différentiation de sérums contenant des anticorps dirigés contre le VHTL-I de sérums contenant des anticorps dirigés contre le VHTL-II, et peptides utilisés pour leur différentiation. L'invention porte également sur des articles manufacturés contenant ces peptides permettant la différentiation de sérums infectés au VHTL-I de sérums infectés au VHTL-II.
Patent CA-2187384-A1 (CA)
Title: Surgical cassette
Inventor: JUNG CHRISTOPHER C
IPC: A61F9/007
Filed: 1996-10-08
Abstract: A cassette having a series of break-off tabs integrally formed in the cassette that can be mechanically or optically sensed by the surgical instrument.
Patent CA-2187734-A1 (CA)
Title: Use of ultrasonics in connection with paper making
Inventor: NILSSON BO
IPC: D21F1/02
Filed: 1995-04-12
Abstract: Method for preventing fibre floccula-tions to occur and to disperse already formed fibre flocculations, better to distribute additive chemicals, to increase fibrillation, to improve reaction and yield from two component chem-icals, to prevent the forming of microbiologi-cal and other types of build-ups onto machine parts and other parts of the white water cir-culations, to prevent the filling of wires and felts, to prevent flocculation in coating equip-ments, to reduce content of air in the stock, and to reduce the foaming. This is achieved by that ultrasonic energy with a frequency of 15 - 60 kHz is added to the stock, machine parts, washing trays or coaters via externally mounted ultrasonic transducers or internally applied submersible ultrasonic units. The ul-trasonic energy is added preferably by means of externally onto the head box mounted ul-trasonic transducers or internally applied sub-mersible ultrasonic units. The level of ultra-sonic energy is controlled by in-line installed formation or flocculation size measurement systems to arrive at desired flocculation. The measured flocculation is used as a criterium for set point optimisation of weight per unit area for the paper or the board produced, and for maximum production per unit of time.