baber/WOPTO huggingface dataset:
Patent EP-3134241-A2 (EP)
Inventor: TABANELLI GIORGIO
IPC: B29C57/02
Filed: 2015-04-14
Abstract: Described is an apparatus for heating end portions (2) of pipes (3) made of thermoplastic material, comprising an internal heating element (8), designed to be inserted at least partially inside an end portion (2) of a pipe (3) made of thermoplastic material for heating an inner cylindrical surface (2b) of the portion (2), the heating element (8) comprising at least one infra-red ray radiation unit (9) which has an operating zone (10) designed to face at least partially the inner cylindrical surface (2b), the operating zone (10) extending longitudinally along a predetermined direction (D), parallel to a central axis (C) of the pipe (3) to be heated.
Patent EP-3166853-A2 (EP)
Title: Tasse à café ainsi que procédé et dispositif pour fabriquer une tasse à café
Inventor: VAN DER VLIET AB
IPC: B65B29/02
Filed: 2015-07-09
Abstract: La présente invention concerne un kit de pièces comprenant une partie tasse (12) et un couvercle séparé (14) qui forment ensemble une tasse à café (200), la partie tasse (12) comprenant : - une paroi inférieure (16) et une paroi latérale circonférentielle (18) - une bride circulaire (26) s'étendant vers l'extérieur à partir d'une extrémité supérieure de la paroi latérale, la bride présentant un bord externe (30) qui présente une épaisseur (31), le couvercle comprenant : - une partie centrale circulaire sensiblement plate (70) configurée pour mettre en prise la surface supérieure (36) de la partie tasse et pour recouvrir l'ouverture supérieure, - une jupe (76) s'étendant vers le bas à partir de la circonférence de la partie centrale, la jupe présentant une longueur de jupe (78), la longueur de jupe (78) étant supérieure à l'épaisseur (31) du bord externe (30) de la bride, la jupe étant configurée pour être pliée autour du bord externe de la bride, - un bord renflé circulaire (80) définissant l'extrémité de la jupe, le bord renflé du couvercle s'étendant vers l'extérieur à partir de la jupe sur une distance (84), le bord renflé étant configuré pour être déformé contre une face inférieure (40) de la bride de la partie tasse afin de fixer le couvercle sur la partie tasse et de former la tasse à café.
Patent EP-3154467-A2 (EP)
Inventor: SAMS STEPHEN
IPC: A61M3/00
Filed: 2015-06-08
Abstract: A syringe assembly may include a syringe having a distal end, a proximal end, and a sidewall extending between the distal end and the proximal end, and a syringe drip guard extending around at least a circumferential portion of the sidewall between the distal end and the proximal end of the syringe. The syringe drip guard may have an outer wall protruding radially outward relative to the sidewall. A channel may be defined between the outer wall of the syringe drip guard and the sidewall of the syringe. The channel may have a closed proximal end and an open distal end. The syringe drip guard may be configured to at least one of: collect, absorb, or adsorb fluid within the channel.
Patent EP-3229815-A2 (EP)
Title: Mononucléotides comportant un groupe disulfure bioréversible
Inventor: BRADSHAW CURT W
IPC: A61K31/7072
Filed: 2015-12-10
Abstract: L'invention concerne un mononucléotide comprenant une nucléobase liée à un sucre ayant une terminaison 3'-carbone et une terminaison 5'-carbone, la terminaison 5'-carbone étant liée à un atome de phosphore (V) d'un groupe phosphate par l'intermédiaire d'un atome d'oxygène, l'atome de phosphore (V) étant lié à (i) un groupe disulfure bioréversible par l'intermédiaire d'un atome d'oxygène ; et (ii) (a) amino éventuellement substitué, alcoxy éventuellement substitué, aryloxy éventuellement substitué ou hétéroaryloxy éventuellement substitué ; ou (b) la terminaison 3'-carbone par l'intermédiaire d'un atome d'oxygène. L'invention concerne également des procédés permettant d'introduire le mononucléotide dans une cellule et des procédés permettant de traiter un sujet atteint d'hépatite C.
Patent EP-3282567-A2 (EP)
Inventor: ENDO KAZUYA
IPC: H01R39/32
Filed: 2017-08-04
Abstract: The electric motor includes a rotor 10 fixed to a rotation axis 4 and spread coaxially in a direction perpendicular to a direction of the rotation axis 4 to be allowed to rotate with the rotation axis 4, a commutator 30 coaxially fixed to the rotation axis 4 to come into sliding contact with a brush by rotating with the rotation axis, and a stator 20 arranged in a periphery of the rotor 10, wherein a felt 15 is mounted on an end of the commutator on a side of the rotor and holds at least partially a conductor wire that supplies a current from a segment to a corresponding winding of the rotor and also the felt 15 and a portion of the conductor wire near the end of the commutator are fixed by a material with which the felt 15 is impregnated and which solidifies when dried.
Patent EP-3285175-A2 (EP)
Inventor: NEEDHAM BRADFORD H
IPC: G06F3/14
Filed: 2013-09-27
Abstract: Various embodiments are generally directed to cooperation among networked devices to perform a multiple-device screen capture in which multiple devices capture what is visually presented on their displays substantially simultaneously. A method comprises transmitting timing information via a network to a first participating device and a second participating device to trigger the first participating device to capture a first image of what is visually presented on a display of the first participating device and the second participating device to capture a second image of what is visually presented on a display of the second participating device substantially simultaneously; and transmitting collection device information via the network to the first and second participating devices specifying a collection device to receive the first and second images. Other embodiments are described and claimed herein.
Patent EP-3478743-A2 (EP)
Inventor: HAAG RAINER
IPC: A61L27/00
Filed: 2017-06-30
Abstract: L'invention concerne un copolymère séquencé amphiphile comprenant un premier bloc constitué d'un domaine hydrophile polymère, le domaine hydrophile polymère étant constitué d'un polyglycérol ; un deuxième bloc facultatif constitué d'un domaine hydrophobe et d'un premier domaine de liaison, le deuxième bloc étant lié de manière covalente au premier bloc par l'intermédiaire du premier domaine de liaison, le domaine hydrophobe étant choisi dans le groupe constitué par des résidus aromatiques comportant 3 à 20 atomes de carbone, des résidus aliphatiques comportant 3 à 20 atomes de carbone, un oligo(diméthylsiloxane) et un poly(diméthylsiloxane) ; un troisième bloc facultatif constitué d'un domaine catéchol et d'un second domaine de liaison, le troisième bloc étant lié de manière covalente au premier bloc par l'intermédiaire du second domaine de liaison, le domaine catéchol comprenant au moins un résidu catéchol ; et un quatrième bloc constitué d'un domaine de réticulation et d'un troisième domaine de liaison, le quatrième bloc étant lié de manière covalente au premier bloc par l'intermédiaire du troisième domaine de liaison, le domaine de réticulation comprenant un résidu réactif permettant une réticulation entre les molécules individuelles du copolymère séquencé amphiphile, le résidu réactif étant au moins un résidu choisi dans le groupe constitué par les amines, les thiols, les allyles, les vinyles, les azides, les alcynes, les carboxyles, les anhydrides, les aldéhydes et la benzophénone.
Patent EP-3483090-A2 (EP)
Inventor: LEDERGERBER PATRICK
IPC: B65F1/06
Filed: 2018-08-30
Abstract: Der erfindungsgemässe Abfallbehälter (2) weist mindestens einen Deckel (6) auf und ist zur Aufnahme eines Abfallbeutels (12) bestimmt, der als Zugbeutel ausgebildet ist. Er weist mindestens eine vom Innenraum nach aussen führende Durchzugsöffnung (20) auf, durch die jeweils ein aus dem Abfallbeutel (12) ragendes Ende (21) eines Zugs (14) so durchziehbar ist, dass dieses mindestens eine Ende (21) von der Aussenseite des Abfallbehälters (2) oder seines mindestens einen Deckels (6) greifbar ist. Der Abfallbeutel (12) kann dadurch mittels des Zugs (14) von aussen geschlossen werden, bevor der Abfallbehälter (2) zur Entnahme des Abfallbeutels (12) geöffnet werden muss. Zur weiteren Verbesserung der Geruchdichte kann die Deckelkonstruktion eine Schleusenkammer aufweisen, mit zwei mit Abstand übereinander liegenden und je durch eine Einwurfklappe verschliessbaren Öffnungen (4). Ebenso kann ein Gerüche neutralisierenden Filter (25) vorhanden sein.
Patent EP-3583208-A2 (EP)
Inventor: CLARKE ELIZABETH JANE
IPC: C12N9/06
Filed: 2018-02-17
Abstract: L'invention concerne des organismes modifiés qui peuvent convertir le méthane ou le méthanol en 3-hydroxypropionate.
Patent EP-3645644-A2 (EP)
Inventor: PANDE HARSHAD
IPC: D21H19/14
Filed: 2018-06-28
Abstract: Lignin formulations for making light- selective mulch, methods of making such lignin formulations, light-selective mulches comprising substrates treated with lignin formulations, and methods of making such light- selective mulches. Some methods involve preparing aqueous lignin formulations that can be used as coatings that, in turn, can be applied to a substrate, such as a paper web, to form a biodegradable, light-selective mulch. Some such mulches blocks at least some light in the ultraviolet and blue/green ranges (350 nm to 500 nm) of the visible light spectrum to inhibit weed growth below the mulch, while also transmitting light in the red/infrared ranges to heat the soil below the mulch.
Patent EP-3658681-A2 (EP)
Title: Concentration based dna sequencing machine
Inventor: ELSOKKARY MOHAMED MOHAMED ADEL
IPC: C12Q1/68
Filed: 2018-07-25
Abstract: The term DNA sequencing is commonly applied to several methods and technologies that are used for determining the order of the nucleotide bases adenine, guanine, cytosine, and thymine in a molecule of DNA. It has many applications in numerous applied fields such as diagnostic, biotechnology, forensic biology and biological systematic, in the sequencing of the human genome, and in the Human Genome Project. In the presented machine, DNA sample fragments are amplified by usual PCR technique. The individual nucleotides are added to the nascent DNA. If the nucleotide is complementary to the tested DNA fragment, a change in the concentration of the added nucleotide could be traced. This change could be detected by any method indicating a complementary nucleotide. Finally, the combined data are used to generate sequence read-outs by computer system.
Patent EP-3619581-A2 (EP)
Inventor: BOYD MARTIN M
IPC: H03L7/26
Filed: 2018-05-01
Abstract: An atomic oscillator device includes an atomic oscillator, a controlled oscillator, a resonance controller, and a cold-atom clock output. The atomic oscillator comprises a two-dimensional optical cooling region (2D OCR) for providing a source of atoms and a three-dimensional optical cooling region (3D OCR) for cooling and/or trapping the atoms emitted by the 2D OCR. The atomic oscillator comprises a microwave cavity surrounding the 3D OCR for exciting an atomic resonance. The controlled oscillator produces an output frequency. The resonance controller is for steering the output frequency of the controlled oscillator based on the output frequency and the atomic resonance as measured using an atomic resonance measurement. The cold-atom clock output is configured as being the output frequency of the controlled oscillator.
Patent EP-3810178-A2 (EP)
Inventor: RICARDO ALONSO
IPC: A61P3/06
Filed: 2019-06-20
Abstract: Provided herein are cyclic polypeptide compounds that can, e.g., bind specifically to human proprotein convertase subtilisin/kexin type 9 (PCSK9) and optionally also inhibit interaction between human PCSK9 and human low density lipoprotein receptor (LDLR), and pharmaceutical compositions comprising one or more of these compounds. Also provided are methods of reducing LDL cholesterol level in a subject in need thereof that include administering to the subject one or more of the cyclic polypeptide compounds or a pharmaceutical composition provided herein.
Patent EP-3902567-A2 (EP)
Inventor: HOROWITZ JULIE
IPC: A61P11/00
Filed: 2019-12-23
Abstract: The present disclosure provides methods of treating patients having a respiratory disorder, methods of identifying subjects having an increased risk of developing a respiratory disorder, and methods of detecting human Arachidonate 15-Lipoxygenase (ALOX15) variant nucleic acid molecules and variant polypeptides.
Patent EP-3849572-A2 (EP)
Inventor: DURRANT CAMERON
IPC: A61K35/17
Filed: 2019-09-10
Abstract: Methods for neutralizing and/or removing human GM-CSF in a subject in need thereof, comprising administering to the subject CAR-T cells having a GM-CSF gene knockout (GM-CSF k/o  CAR-T cells) are provided. Also provided are methods for  GM-CSF  gene inactivation or  GM-CSF  knockout (KO) in a cell comprising targeted genome editing or GM-CSF gene silencing. Methods for preventing/treating immunotherapy-related toxicity, comprising administering to the subject CAR-T cells having a  GM-CSF  gene inactivation or  GM-CSF  knockout (GM-CSF k/o  CAR-T cells), wherein the  GM-CSF  gene is inactivated or knocked out and/or a recombinant GM-CSF antagonist are provided. Methods for reducing a level of a cytokine or chemokine other than GM-CSF in a subject having immunotherapy-related toxicity comprising administering to the subject a recombinant hGM-CSF antagonist are provided. Also provided are methods for treating or preventing immunotherapy-related toxicity in a subject, comprising administering to the subject chimeric antigen receptor-expressing T-cells (CAR-T cells), the CAR-T cells having a GM-CSF gene knockout (GM-CSF k/o  CAR-T cells). Methods for preventing or reducing blood-brain barrier disruption in a subject treated with immunotherapy, the method comprising administering CAR-T cells having a GM-CSF gene knockout (GM-CSF k/o  CAR-T cells) to the subject, also are provided.
Patent EP-3705293-A2 (EP)
Inventor: BEE JENNIFER
IPC: B32B38/06
Filed: 2018-09-28
Abstract: One or more aspects of the present disclosure provide optical element transfer structures that include an optical element releasably coupled with a transfer medium and methods of making and using the optical element transfer structures. The optical element transfer structures can be used to dispose an optical element onto an article, whereby the optical element imparts a structural color to the article.
Patent EP-3739751-A2 (EP)
Inventor: HO CHEN-YEN
IPC: H03F3/193
Filed: 2020-04-23
Abstract: An envelope tracking supply modulator includes an amplifier circuit and a zero peaking circuit. The amplifier circuit receives an envelope input, generates a modulated supply voltage according to the envelope input, and provides the modulated supply voltage to a power amplifier. The zero peaking circuit is coupled to the amplifier circuit, and applies zero peaking to the amplifier circuit, where the zero peaking inserts a zero at a frequency.
Patent EP-3760713-A2 (EP)
Inventor: BALUMURI PADMAVATHI
IPC: C12N9/20
Filed: 2015-05-26
Abstract: The present invention relates to a lipase variant of a parent lipase, which variant has lipase activity, at least 75% but less than 100% sequence identity to SEQ ID NO: 3 and comprises a substitution at one or more positions corresponding to positions 125; 1; 2; 3; 4; 5; 6; 7; 9; 10; 11; 12; 16; 19; 30; 31; 34; 36; 37; 39; 40; 42; 44; 51; 52; 53; 54; 56; 58; 59; 70; 71; 72; 73; 83; 84; 86; 88; 90; 92; 93; 95; 96; 100; 101; 102; 104; 106; 109; 110; 112; 117; 119; 124; 127; 128; 131; 132; 133; 134; 135; 137; 158; 159; 160; 161; 162; 163; 165; 166; 167; 168; 170; 181; 182; 183; 189; 190; 192; 194; 196; 202; 210; 211; 212; 220; 225; 227; 228; 229; 230; 231; 233; 237; 238; 239; 240; 242; 246; 247; 248; 252; 259; 262; 264; 269 of SEQ ID NO: 3. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
Patent EP-3931082-A2 (EP)
Inventor: GLEAVE JAMES
IPC: E05C3/06
Filed: 2020-02-24
Abstract: Apparatus to monitor the position of an aircraft landing gear.
Patent EP-4031317-A2 (EP)
Inventor: KUECKENDAHL PETER J
IPC: B23K26/04
Filed: 2020-09-18
Abstract: An electromagnetic radiation system for directing an electromagnetic radiation beam at a target having a first arrangement in which the radiation beam is directed along a marking beam path that is within a marking range of the electromagnetic radiation system and a second arrangement in which the radiation beam is directed along a different beam path that is not within the marking range of the electromagnetic radiation system, wherein a positional relationship between the marking beam path and the different beam path satisfies a predetermined condition at the target when the electromagnetic radiation system is at a predetermined distance from the target.
Patent EP-3923140-A2 (EP)
Inventor: WANG XIAOLONG
IPC: G06F11/07
Filed: 2021-05-07
Abstract: The present application discloses a fault prediction method and apparatus, electronic device and a storage medium, and relates to fields of cloud computing and fault processing. The specific solution is as follows: acquiring (S101) a fault alarm request, wherein the fault alarm request is obtained by at least two fault triggering parameters of a fault generated by cloud operation, a hidden danger generated by cloud operation, and a change generated by terminal operation at a user level; analyzing (S102) the fault alarm request, to obtain at least two fault triggering parameters of the fault, the hidden danger, and the change; establishing (S103) an association between the at least two fault triggering parameters of the fault, the hidden danger, and the change, to obtain an association result; and predicting (S104) a fault causing the fault alarm request according to the association result, to obtain a fault prediction result.
Patent EP-3922819-A2 (EP)
Inventor: NEWMAN STEPHEN WALTER
IPC: F01D5/18
Filed: 2021-05-25
Abstract: A cast turbine (108) nozzle (112) includes an airfoil (130) having a body (128) including a suction side (132), a pressure side (134) opposing the suction side (132), a leading edge (136) spanning between the pressure side (134) and the suction side (132), a trailing edge (138) opposing the leading edge (136) and spanning between the pressure side (134) and the suction side (132), and a cooling cavity (150) defined by an inner surface (152) of the body (128). The nozzle (112) also includes at least one endwall (120, 122) connected with the airfoil (130) along the suction side (132), the pressure side (134), the trailing edge (138) and the leading edge (136), and a plurality of heat transfer protrusions (160) extending inwardly from the inner surface (152) within the body (128), the plurality of heat transfer protrusions (160) extending from the leading edge (136) along the suction side (132) and along the pressure side (134) in a radially staggered columnar pattern. The inner surface (152) includes a planar surface (164) extending between adjacent heat transfer protrusions (160).
Patent EP-4062777-A2 (EP)
Inventor: ZOUEV ALEXANDER
IPC: A24F40/57
Filed: 2021-11-15
Abstract: In order to provide a novel and unobvious hookah and/or hookah sub-assembly as well as a corresponding method, the present invention proposes 
(a) providing a hookah sub-assembly including a heating element, a heat exchanger and tobacco or other substance to be smoked disposed below the heat exchanger and the heating element, wherein the tobacco or other substance to be smoked evaporates at a first temperature; 
(b) heating the heating element to a second temperature which is higher than said first temperature; and 
(c) insulating the tobacco or other substance to be smoked from the heating element and the heat exchanger of the hookah sub-assembly so that a temperature the tobacco or other substance to be smoked is exposed to is less than the first temperature when the hookah sub-assembly is operating but is not being used to smoke tobacco or other substance to be smoked and a temperature the tobacco or other substance to be smoked is exposed to is greater than or equal to the first temperature when the hookah sub-assembly is operating and is being used to smoke tobacco or other substance to be smoked.
Patent EP-4126013-A2 (EP)
Title: Tumor antigens for liver cancer immunotherapy
Inventor: TAGLIAMONTE MARIA
IPC: A61K39/00
Filed: 2021-04-01
Abstract: The present invention relates to tumor antigens and their use in cancer immunotherapy. In particular, the present invention relates to HERV epitopes and tumor associated antigens (TAAs) expressed by liver cancer cells and which, preferably in combination with epigenetic drugs, can be used in tumor vaccination therapies in the treatment and prevention of liver cancer, preferably hepatocellularcarcinoma (HCC).
Patent EP-4178592-A2 (EP)
Inventor: BZDZION LUKASZ
IPC: A61K35/28
Filed: 2021-07-08
Abstract: The subject of invention is a method of encapsulating an active protein using electrodeposition techniques, characterised in that it comprises the following steps: (a) establishing a primary mesenchymal cell culture containing 2,000-5,000 source tissue cells and a serum-supplemented culture medium; (b) maintaining the cell culture established in step (a) for 280-340 hours until the culture surface is fully covered by the cultured cells; (c) obtaining a culture fluid from the above of the cultured cells; (d) purifying the culture fluid obtained in step (c) from cell debris and suspended cells by centrifuging said fluid with a force of 300 to 1200 x g; (e) transferring the upper liquid phase from above the sediment to a new vessel; (f) gently mixing the purified liquid phase obtained in step (e) with an aqueous solution of polyvinyl alcohol; (g) adding ethyl alcohol to the mixture obtained in step (f) while stirring continuously; (h) the material obtained in step (g) is deposited on the collector surface by means of electro spinning or electrospraying. Another subject of invention is an immunomodulating composition containing an active protein and a polymer, characterised in that it contains ethyl alcohol, wherein the active protein is a fibrous, fully water-soluble material containing proteins released by mesenchymal cells, including CCL2 at an amount from 0.56 to 5.62 ng/g of dry weight of the composition, and the polymer is an aqueous solution of polyvinyl alcohol. Another subject of invention is an use of the composition according to the invention for the preparation of a pharmaceutical composition for the treatment of atopic dermatitis in humans.
Patent EP-4176060-A2 (EP)
Inventor: GUPTA NACHI
IPC: C12N15/11
Filed: 2021-07-02
Abstract: La présente divulgation concerne des séquences d'acide nucléique modifiées codant pour l'insuline et la glucokinase, des cassettes d'expression et des vecteurs d'administration les comprenant, ainsi que leurs méthodes d'administration pour le traitement du diabète.
Patent EP-4214238-A2 (EP)
Inventor: GOULET DENNIS R
IPC: C07K16/28
Filed: 2021-09-21
Abstract: L'invention concerne un domaine de liaison ayant une spécificité de liaison à l'EGFR humain (récepteur du facteur de croissance de l'épithélium) comprenant un domaine VH et un domaine VL, le domaine VH et VL comprenant chacun indépendamment une séquence ayant au moins 90% d'identité de séquence avec une séquence d'acides aminés telle que décrite ci-dessus. L'invention concerne en outre des anticorps comprenant le domaine de liaison.
Patent EP-4027484-A2 (EP)
Title: Method for charging a battery system and mobile construction machine
Inventor: RITZER-VAN DINTHER JEROEN
IPC: H02J7/34
Filed: 2022-01-12
Abstract: Method for charging a battery system, characterised in that the battery system is wholly or partially charged by means of electricity supplied and/or generated by a mobile power plant (5), the electricity preferably being generated by the mobile power plant wholly or partially from renewable energy sources (7, 8), such as solar and/or wind energy.