baber/WOPTO huggingface dataset:
Patent CA-3118195-A1 (CA)
Inventor: ZANARDI LUCA
IPC: F28D21/00
Filed: 2019-12-19
Abstract: In a heat exchanger with double-walled tubes (11), an end junction (10) between inner tube (12) and outer tube (13) comprises an end plate (15) in which there is a seat (16) in which an end portion of the inner tube (12) is housed. The corresponding outer tube (13) is peripherally fixed sealingly around the opening (17) of the seat and a deflector (25) extends the inner wall of the outer tube (13) inside the seat (16) so as to define a toroidal cavity (26) between the deflector (25) and a side wall (18) of the seat (16). The seat (16) is closed by a bottom (19) which is opposite to the opening (17) of the seat and which has a passage (20) connected sealingly to the end of the inner tube (12) in the seat for the transit of the fluid to be cooled. A radial space (27) is present near the said bottom (19) between the toroidal cavity (26) and internal cavity (14) of the double-walled tube, and the end plate (15) has at least one conduit (22) which emerges inside the toroidal cavity (26) for the inflow or outflow of the cooling fluid. In this way a junction (11) and an exchanger (40) with such a junction which are robust and have innovative performance features may be provided.
Patent CA-3118210-A1 (CA)
Title: 3.beta.-(benzyloxy)-17.alpha.-methyl-pregn-5-en-20-one for use in the treatment of cognitive disorders
Inventor: PIAZZA PIER-VINCENZO
IPC: A61P25/28
Filed: 2019-12-18
Abstract: The present invention generally relates to a specific pregnenolone derivative for its use for the treatment of a cognitive disorders. More particularly, the invention relates to a compound of Formula (I) for its use in the treatment of cognitive disorders. Indeed, the compound of the inventionis in vivo very potent in correcting the cognitive impairments observed in cognitive disorders.
Patent CA-3118641-A1 (CA)
Title: Compositions and methods
Inventor: GILBERT SARAH C
IPC: A61K39/25
Filed: 2019-11-05
Abstract: The invention relates to a viral vector comprising nucleic acid having a polynucleotide sequence encoding at least one epitope of the varicella-zoster virus (VZV) Gly E antigen, wherein said viral vector is an adenoviral vector. The invention also relates to uses, compositions for use in medical treatments, and methods of medical treatment.
Patent CA-3121420-A1 (CA)
Title: Anti-il-27 antibodies and uses thereof
Inventor: HILL JONATHAN
IPC: A61K39/395
Filed: 2019-09-25
Abstract: The present disclosure relates to anti-IL-27 antibodies, and antigen-binding portions thereof. The disclosure also relates to methods for treating or ameliorating one or more symptoms of a disease, such as cancer, by administering the antibodies or antigen-binding portion thereof. The disclosure also relates to methods for detecting IL-27 in, for example, a subject or a sample.
Patent CA-3121491-A1 (CA)
Title: System, method, and medium for configuring operation of a pilot plant for in-situ extraction of hydrocarbon material
Inventor: BINESH RAZ
IPC: E21B43/16
Filed: 2021-06-08
Abstract: There are provided systems, methods, and processor-readable media for configuring operation of a pilot plant based on statistical power analysis.  The pilot plant is configured for testing of hydrocarbon material extraction technologies. The statistical power analysis facilitates establishing an operating time interval, representative of a time interval, for operating the pilot plant, sufficient to collect a minimum number of pilot plant data samples sufficient to predict that producing hydrocarbon material from the subterranean formation via in-situ extraction using the test technology exhibits a pre-determined effect size relative to a baseline technology.
Patent CA-3122276-A1 (CA)
Title: Improved syringe and gasket systems
Inventor: ABRAMS ROBERT S
IPC: C08J7/12
Filed: 2019-12-06
Abstract: A process for producing gaskets with an improved channel for use in matched syringe and plunger systems, preferably prefilled plastic syringe systems. In particular, an improved process for making and inspecting continuous channels in a gasket film by laser treatment. The gaskets are useful in matched syringe and plunger systems with high and consistent container closure integrity (CCI), and consistent break loose and glide forces over time, and sealability.
Patent CA-3126213-A1 (CA)
Inventor: WENTHOLD RANDY
IPC: A61M1/34
Filed: 2020-01-13
Abstract: Disclosed are methods, systems, and devices for removing cytokines and other substances from blood of a subject in a closed fluid circuit. The methods, systems, and devices involve: (i) passing venous blood from the subject through a plasma separator, thereby separating the blood into blood cells and plasma; (ii) passing the plasma received from the plasma separator through an adsorption chamber located in the circuit to form processed plasma, where materials in the adsorption chamber adsorb cytokines in the plasma to form the processed plasma, and where the materials include, by weight, 50-70% activated carbon and 30-50% non-ionic resin; (iii) combining the processed plasma, received directly from the adsorption chamber, with the blood cells in a combining chamber to form processed blood, without exchanging any of the plasma for another fluid; and (iv) transfusing the processed blood from the circuit directly into the subject, where no fluid besides the subject's blood is added to the circuit before the transfusing of the processed blood into the subject is completed.
Patent CA-3127380-A1 (CA)
Inventor: BLACKMAN BENJAMIN
IPC: F16C17/10
Filed: 2020-01-21
Abstract: L'invention concerne une rondelle de butée et un différentiel contenant une rondelle de butée. Le différentiel comprend un boîtier, un croisillon et un ou plusieurs pignons satellites. La rondelle de butée comprend un corps ayant une forme annulaire et une largeur configurée de façon à correspondre approximativement à une largeur du ou des pignons satellites. La rondelle de butée est en outre configurée de façon à venir en prise avec le croisillon de façon à empêcher ou à réduire la rotation de la rondelle de butée par rapport au boîtier quand la rondelle de butée est installée dans le différentiel.
Patent CA-3127489-A1 (CA)
Title: Current device readout system
Inventor: PRZYBYSZ ANTHONY JOSEPH
IPC: G06N10/00
Filed: 2020-01-29
Abstract: A current device readout system and a method for reading a current state of a current device are provided. The system includes a tunable resonator (16) having a resonant frequency that is associated with a current state of a current device (12) being configured as flux qubit. The tunable resonator can be configured to receive a tone signal having a predetermined frequency from a feedline (20) to determine the current state of the current device. The system also includes an isolation device (18) inductively interconnecting the tunable resonator and the current device. The isolation device is configured as a quantum flux parametron and can be tunable to isolate the current device in a first state and to facilitate the determination of the current state of the current device in a second state.
Patent CA-3131721-A1 (CA)
Inventor: SAYED ASHLEY JOHN
IPC: A24F40/50
Filed: 2020-03-09
Abstract: An aerosol provision device (100) comprises a heater assembly (304) configured to heat aerosol generating material (110a), an indicator assembly (306), an input interface (112) configured to receive an input for selecting a heating mode from a plurality of heating modes comprising a first mode and a second mode and a controller (302). The controller is configured to detect the input for selecting the heating mode and, responsive to detecting the input: (i) determine a selected heating mode based on the input, (ii) cause the heater assembly to begin heating the aerosol generating material according to the selected heating mode, and (iii) cause the indicator assembly to indicate that the device is ready for use within a predetermined period of time after causing the heater assembly to begin heating the aerosol generating material.
Patent CA-3134714-A1 (CA)
Title: Methods and systems for controlling welding fume extraction
Inventor: RITCHOT ROB
IPC: B23K9/32
Filed: 2021-09-28
Abstract: A system and method for controlling fume extraction during a welding process that includes a control system that is operatively connected to a welding work cell for regulating the fume extraction flow rate for each weld in a welding sequence comprising at least two or more welds.
Patent CA-3137598-A1 (CA)
Title: Dna-dependent protein kinase inhibitor
Inventor: Qi changhe
IPC: A61P35/00
Filed: 2020-05-26
Abstract: Disclosed herein are compounds of Formula (I), and pharmaceutically acceptable salts thereof, that are useful as DNA-PK inhibitors. Also disclosed are pharmaceutical compositions comprising one or more compounds of Formula (I), and methods of using such compounds or compositions to treat DNA-PK related disorder (e.g., cancer).
Patent CA-3138329-A1 (CA)
Title: Regulatory nucleic acid molecules for enhancing gene expression in plants
Inventor: MEULEWAETER FRANK
IPC: A01H5/00
Filed: 2020-05-06
Abstract: The present invention is in the field of plant molecular biology and provides methods for production of high expressing promoters and the production of plants with enhanced expression of nucleic acids wherein nucleic acid expression enhancing nucleic acids (NEENAs) are functionally linked to said promoters and/or introduced into plants.
Patent CA-3138676-A1 (CA)
Title: Procede et machine d'automatisation de fabrication d'un objet selon un procede de fabrication additive de type solide/solide, couche par couche
Inventor: PELAINGRE CYRIL
IPC: B33Y10/00
Filed: 2020-06-26
Abstract: Procédé et rnachine permettant l'automatisation de fabrication d'un objet selon un procédé de fabrication additive de type solide/solide, couche par couche, la rnachine (1) comprenant une table à  dépression (2) et au moins un outil d'usinage monté mobile en déplacement au-dessus de la table (2).  Elle comporte en outre, un poste de retournement (4) comprenant d'une part une traverse (42), mobile longitudinalement au-dessus de la table (2) et mobile verticalernent, portant un moyen (43) préhenseur d'une plaque (M) monté mobile en rotation selon un axe parallèle à  la traverse (42), et d'autre part un moyen (45) support d'une plaque, (M) conçu apte à autoriser la préhension de celle-ci par l'une ou l'autre de ses deux faces, au travers du moyen préhenseur (43), et d'autre part encore des moyens (21) de calage en X et Y aptes à permettre le repérage et le positionnement d'une plaque (M), d'une panoplie ou d'une strate.
Patent CA-3139049-A1 (CA)
Title: Reagent storage in an assay device
Inventor: KUMAR SUDEEP
IPC: G01N33/543
Filed: 2011-10-13
Abstract: The invention relates to methods for conducting binding assays in an assay device that includes one or more storage and use zone. The storage zones of the assay device are configured to house one or more reagents used in an assay conducted in the use zone of the device.
Patent CA-3139843-A1 (CA)
Title: Rechargeable battery cell
Inventor: ZINCK LAURENT
IPC: H01M4/131
Filed: 2020-07-30
Abstract: The invention relates to a rechargeable battery cell (2, 20, 40) which contains an active metal, at least one positive electrode (4, 23, 44) with a diverting element (26), at least one negative electrode (5, 22, 45) with a diverting element (27), a housing (1, 28), and an electrolyte, wherein the negative electrode contains lithium metal at least when the rechargeable battery cell is charged, and the electrolyte is based on SO2 and contains at least one first conductive salt with the formula (I), in which M is a metal selected from the group consisting of alkali metals, alkaline earth metals, metals of group 12 of the periodic table, and aluminum; x is a whole number from 1 to 3; the substituents R1, R2, R3, and R4 are selected independently of one another from the group consisting of C1-C10 alkyl, C2-C10 alkenyl, C2-C10 alkinyl, C3-C10 cycloalkyl, C6-C14 aryl, and C5-C14 heteroaryl; and Z is aluminum or boron.
Patent CA-3141205-A1 (CA)
Title: Modular christmas tree
Inventor: MARCHANT MICHAEL JAMES
IPC: A47G33/06
Filed: 2020-05-13
Abstract: The present invention provides a modular Christmas tree comprising three or more sides that rise from a floor to give the tree a tapering shape, and central support structures that extend outwardly to support the sides. Each side comprises elongate pieces joined together with connectors that allow the series of elongate pieces to be separated for storage of the disassembled Christmas tree. Each central support structures includes a hub that supports each side. Some hubs also comprise spokes that extend from those hubs to each side. The hubs, spokes and sides are joined by connectors that allow the tree to be disassembled for compact storage. This is in contrast to traditional artificial Christmas trees that can be at least partly disassembled or folded into a more compact configuration for storage, which are still bulky in their stored states and require a substantial volume.
Patent CA-3142890-A1 (CA)
Inventor: BOWERS SIMEON
IPC: C07D253/02
Filed: 2020-06-12
Abstract: La présente invention concerne de nouveaux composés pouvant se lier à PCSK9, modulant ainsi l'activité biologique de PCSK9. L'invention concerne également des compositions comprenant ces composés, des procédés de préparation des composés, et des procédés d'utilisation des composés dans le traitement d'états et de maladies liés à PCSK9.
Patent CA-3143032-A1 (CA)
Title: Compositions and methods for treatment of fungal infections
Inventor: SELSTED MICHAEL E
IPC: C07K11/02
Filed: 2020-06-26
Abstract: Novel peptide analogs of a ?-defensin have been developed that provide a biphasic effect in treating disseminated fungal disease and/or associated septic shock. These analogs are active at concentrations below those needed to provide a fungicidal effect, and function by initially mobilizing effector cells of the immune system to address the infective organism followed by regulation of the immune system to down regulate the inflammatory response. These novel ?-defensin analogs are protective at concentrations where naturally occurring ?-defensin have no apparent effect, and include a core set of structural and sequence features not found in native ?-defensin
Patent CA-3143079-A1 (CA)
Title: Novel galactoside inhibitor of galectins
Inventor: ZETTERBERG FREDRIK
IPC: C07H19/04
Filed: 2020-07-03
Abstract: The present invention relates to a D-galactopyranose compound of formula (1) wherein the pyranose ring is a-D-galactopyranose, and these compounds are high affinity galectin-3 inhibitors for use in treatment of inflammation; Inflammation induced thrombosis; Atopic dermatitis; Acute coronary syndrome; fibrosis, such as pulmonary fibrosis, liver fibrosis, kidney fibrosis, ophthalmological fibrosis and fibrosis of the skin and heart; local fibrosis such as Dupuytren's disease and Peyronie's disease; fibrotic complications of other therapies such as coronary stents, bile duct stents, cerebral artery stents, ureter stents; scleroderma; scarring; keloid formation; covid-19; acute lung injury; ARDS; viral pneumonitis, aberrant scar formation; surgical adhesions; septic shock; cancer, such as colorectal cancer, other gastrointestinal carcinomas such as pancreatic cancer, gastric cancer, biliary tract cancer, lung cancers, mesothelioma, female cancers like breast cancer, ovarian cancer, uterine cancer, cancer of the cervix uteri, cancer of the salpingx, cerebral cancers such as medulloblastomao, glioma, meningioma, sarcomas of the bones and muscles and other sarcomas, leukemias and lymphomas, such as T-cell lymphomas; transplant rejection; metastasising cancers; ageing; Dementia; Alzheimers; TGFbeta driven bone disease such as osteogenesis imperfecta; Pulmonary hypertension; autoimmune diseases, such as psoriasis, rheumatoid arthritis, Rheumatoid lung; Crohn's disease, ulcerative colitis, ankylosing spondylitis, systemic lupus erythematosus; viral infections such as influenza virus, HIV, Herpes virus, Coronaviruses, Hepatitis C; metabolic disorders; heart disease; heart failure; pathological angiogenesis, such as ocular angiogenesis or a disease or condition associated with ocular angiogenesis, e.g. neovascularization related to cancer; and eye diseases, such as age-related macular degeneration and corneal neovascularization; atherosclerosis; metabolic diseases; diabetes; type I diabetes; type 2 diabetes; insulin resistens; obesity; Marfans syndrome; LoeysDietz syndrome; nephropathy; Diastolic HF; fibrotic lung complications of aPD1 and other CPI therapies; asthma and other interstitial lung diseases, including Hermansky-Pudlak syndrome, liver disorders, such as non- alcoholic steatohepatitis or non-alcoholic fatty liver disease; uterine disease such as uterine fibroids and uterine or cervical fibrosis.
Patent CA-3144177-A1 (CA)
Title: Pharmaceutical compositions for glucagon and glp-1 co-agonist peptides
Inventor: GOMES DOS SANTOS ANA LUCIA
IPC: A61P3/06
Filed: 2020-06-30
Abstract: The present invention provides formulations for parenteral administration of GLP- 1/Glucagon agonist peptides, methods of making such formulations, and methods of treatment using such formulations.
Patent CA-3144940-A1 (CA)
Inventor: TRAN SANG
IPC: A61H35/00
Filed: 2022-01-07
Abstract: Apparatus, for use with a bowl and a seat such that the feet of a seated person can be in the bowl, comprising: a pair of pads each having a base and an end and having a first position wherein the base and end are respectively proximal and distal to the seat and the pad extends horizontally from the base to the end;  a second position wherein the end and base are respectively proximal and distal to the seat and the pad extends horizontally; a third position wherein the base and end are respectively proximal and distal to the seat, and the end is above the base; a fourth position wherein the end and base are respectively proximal and distal to the seat and the end is above the base, when in the same position, the pads are spaced in the direction between the ischial bones of the person.
Patent CA-3145394-A1 (CA)
Title: Compose derive introduisant un groupe biphenyle dans un nouvel acide aminoalcanoique et composition pharmaceutique antifongique le comprenant
Inventor: PARK KI DUK
IPC: A61P31/10
Filed: 2020-06-25
Abstract: La présente invention concerne un dérivé fonctionnel d'acides aminés d'alanine et de proline afin de fournir des dérivés, et des sels et/ou des solvates de ceux-ci, un groupe biphényle étant introduit dans un nouvel acide aminoalcanoïque. Le composé selon la présente invention a d'excellents effets antifongiques et fongicides. En outre, il a été confirmé que le composé selon la présente invention a un effet synergique lorsqu'il est administré en combinaison avec un agent antifongique existant. En outre, le composé selon la présente invention présente une activité contre une large gamme de champignons. Par conséquent, le composé selon la présente invention peut être largement utilisé dans des domaines nécessitant un traitement à l'aide d'agents antifongiques ou fongicides contre des champignons pathogènes chez les humains, des champignons pathogènes chez les animaux et des champignons phytopathogènes.
Patent CA-3154111-A1 (CA)
Inventor: JAIN DHARAMDEEP
IPC: C09D171/00
Filed: 2020-09-14
Abstract: A method of installing a roof system includes providing a first membrane composite; adhesively securing the first membrane composite to a roof surface through a UV-cured pressure-sensitive adhesive layer; providing a second membrane composite; adhesively securing the second membrane composite to the roof surface through a UV-cured pressure-sensitive adhesive layer, where the second membrane composite is positioned adjacent to and partially overlapping a lap area of the first membrane composite; and adhesively securing the second membrane composite to a first planar surface of the first membrane composite along a primer layer through the UV-cured pressure-sensitive adhesive layer disposed on the second membrane composite.
Patent CA-3154635-A1 (CA)
Title: A decentralized synchronization solution for wireless communication networks
Inventor: JUVEN VILLE
IPC: H04W72/12
Filed: 2020-08-26
Abstract: The invention relates to a wireless communication system (100) comprising a plurality of radio devices (102, 104). Each radio device of the plurality of radio devices (102, 104) is configured to: obtain timing information representing timing schedules of one or more other radio devices (102, 104) within its neighborhood; define, based on the obtained timing information, at least one timing schedule group (106, 108) into which the plurality of radio devices (102, 104) are divided and a size of each at least one timing schedule group (106, 108); and synchronize its own timing schedule with the timing schedule of the timing schedule group (106, 108) with the largest size. The invention relates also to a synchronization method (500) for the wireless communication system (100), a radio device (102, 104) for a wireless communication system, and a synchronization method for the radio device (102, 104).
Patent CA-3155604-A1 (CA)
Inventor: MACEDO DAVID SIMON
IPC: G01N27/30
Filed: 2020-11-06
Abstract: The invention provides a solid state reference electrode comprising: a reference element in ionic communication with a composite, the composite comprising a water-permeable polymeric matrix loaded with a solid inorganic salt comprising a reference anion; an electrode surface for contacting an analyte; and a solid ion-exchange material located between the electrode surface and the reference element, the solid ion-exchange material comprising one or more non-interfering ions, wherein in use the solid ion-exchange material immobilises one or more interfering ions, when present in solution in the analyte, by exchange with the non-interfering ions.
Patent CA-3157607-A1 (CA)
Inventor: LI CHANGBAO
IPC: C12N15/09
Filed: 2020-11-24
Abstract: La transformation génique classique nécessite une culture tissulaire, et certaines lignées d'élite présentent une très faible efficacité de transformation dans la culture tissulaire. L'invention concerne des procédés de transformation in planta. Selon certains aspects, un méristème axillaire d'une plante est blessé et mis en contact avec un agent de transformation. Le méristème axillaire blessé est ensuite régénéré et traité avec une étape de sélection, conduisant à un tissu transformé qui peut produire des graines transgéniques.
Patent CA-3158293-A1 (CA)
Title: Composition lipidique
Inventor: SEKIGUCHI TAKAHIRO
IPC: A61K31/7088
Filed: 2020-11-13
Abstract: La présente invention aborde le problème de la fourniture d'une composition lipidique qui réalise une excellente administration d'une grande variété d'acides nucléiques. La présente invention concerne une composition lipidique comprenant : un premier lipide qui est un lipide représenté par la formule (1) ou un sel de celui-ci ; un stérol ; et un acide nucléique. Le rapport du nombre de moles du premier lipide dans la composition lipidique au nombre de moles du stérol dans la composition lipidique est supérieur ou égal à 0,300 mais inférieur à 1,299. Dans la formule : X représente -NR1- ou -O- ; R1 représente un atome d'hydrogène, un groupe hydrocarboné ou similaire ; R2 et R3 représentent chacun indépendamment un atome d'hydrogène, un groupe hydrocarboné ou similaire ; R4, R5, R6, R7, R8, R9, R10, R11 et R12 représentent chacun indépendamment un atome d'hydrogène ou un groupe alkyle ; des résidus d'au moins une paire choisie parmi R4 et R5, R10 et R5, R5 et R12, R4 et R6, R5 et R6, R6 et R7, R6 et R10, R12 et R7, et R7 et R8 peuvent se lier les uns avec les autres et former un cycle de 4 à 7 chaînons qui peut contenir un atome O ; et a, b, c et d représentent chacun indépendamment un nombre entier de 0 à 3, a+b étant égal à 1 ou plus et c+d étant égal à 1 ou plus.