baber/WOPTO huggingface dataset:
Patent CA-2608873-A1 (CA)
Inventor: SILENCE KAREN
IPC: C07K16/36
Filed: 2006-05-19
Abstract: There is provided a nanobody against Von Willebrand Factor (vWF) consisting of framework regions, FR1 to FR4, and 3 complementarity determining regions, CDR1 to CDR3, wherein: CDR1 comprises a sequence that has 0 or 1 amino acid difference across the entire length thereof compared to YNPMG; CDR2 comprises a sequence that has 0 to 2 amino acid differences across the length thereof compared to the sequence selected from the group consisting of:  AISRTGGSTYYPDSVEG, AISRTGGSTYYARSVEG, SISWSGTYTAYSDNVKG, GISWSGVSTDYAEFAKG, SISWSGSYTAYADNVKG, SISWSGMSTYYTDSVKG, TITSGGRTSYADSVKG, AISWSGGLTYYADSVKG, TITSGGSTNYADPVKG, and TITSGGSTNYADSVKG; and CDR3 comprises a sequence that has 0 to 2 amino acid differences across the length thereof compared to the sequence selected from the group consisting of:  AGVRAEDGRVRTLPSEYTF, AGVRAEDGRVRSLPSEYTF, AGVRAEDGRVRTLPSEYNF, QSRYRSNYYDHDDKYAY, LGRYRSNWRNIGQYDY, QSRYSSNYYDHDDKYAY, SNRYRTHTTQAMYNY, VVDGKRAP, NRRQKTVQMGERAYDY, NLKQGSYGYRFNDY, and NLKQGDYGYRFNDY. There is also provided nucleic acids encoding, host cells capable of expressing, compositions comprising, uses of, and methods of producing said nanobodies.
Patent CA-2609997-A1 (CA)
Inventor: MAEDA HIROHITO
IPC: G03G9/12
Filed: 2006-06-26
Abstract: Disclosed is a process for production of a liquid developer for use in electrophotograph or electrostatic recording by coacervation method. The process can produce a liquid developer in which a coloring agent (e.g., a pigment) is included completely within a resin particle by distillation of a solvent while retaining the state where the coloring agent are finely dispersed and the resulting colored resin particle is small in particle size and has an excellent dispersion stability, and which has excellent optical properties. The process comprises preparing a mixture containing a pigment, a resin having a fixability, a solvent (A) which can dissolve the resin therein, a hydrocarbon solvent (B) which cannot dissolve the resin therein and has an SP value lower than that of the solvent (A) and at least one dispersing agent which is soluble in both of the solvents (A) and (B), and distilling away the solvent (A) from the mixture to cause the resin dissolved in the mixture to precipitate, whereby a colored resin particle having the pigment included therein is dispersed in the solvent (B).
Patent CA-2610691-A1 (CA)
Inventor: SAGOT YVES
IPC: A61P25/00
Filed: 2006-06-02
Abstract: The invention relates to the use of an IL18-BP isoform that does not bind to IL18, or of an agonist thereof, for treatment or prevention of a neurological and/or inflammatory disease. Preferred isoforms for use in the frame of the present invention include IL-18BPb and IL-18BPd.
Patent CA-2611732-A1 (CA)
Title: Automated detection and control system and method for high pressure water wash application and collection applied to aero compressor washing
Inventor: NORDLUND SEBASTIAN
IPC: B64F5/40
Filed: 2007-11-21
Abstract: The present invention relates to a system and method for washing gas turbine engines comprising a manifold comprising one or more tubes; a pumping system for providing pressurized washing liquid to the manifold, the pumping system comprising a pump, and one or more valves; and a control unit for regulating the pumping system according to washing parameters associated to a particular engine.
Patent CA-2613608-A1 (CA)
Title: Novel intermediates useful for the preparation of coenzymes, process for the preparation of novel intermediates and an improved process for the preparation of coenzymes
Inventor: ROY MITA
IPC: C07C50/28
Filed: 2006-06-21
Abstract: The present invention relates to novel intermediates for the preparation of coenzymes, processes for the preparation of the intermediates and an improved process for the preparation of Coenzymes. The present invention particularly relates to an improved process for the preparation of Coenzyme Q , more particularly for Conenzyme Q9 and Coenzyme Q10. Still more particularly this invention relates to regio and stereo controlled process for the preparation of Coenzyme Q9 and Coenzyme Q10 of the formula (I), where n = 9 (Coenzyme CoQ9) , and where n = 10. (Coenzyme CoQ10).
Patent CA-2617051-A1 (CA)
Inventor: FRIJLINK HENDERIK WILLEM
IPC: A61K31/00
Filed: 2005-07-29
Abstract: The invention relates to delivery systems that allow for the pulsatile release of a substance, such as a drug, in response to a change in pH. More specifically, it relates to drug administration to the GI tract, in particular to site-specific intestinal drug delivery via the oral route. Provided is a pH-controlled pulsatile release system (PPRS) comprising a core surrounded by a coating layer, wherein said core comprises an active substance and wherein said coating layer comprises a pH-sensitive coating material wherein a swellable agent is embedded. Said swellable agent is capable of taking up at least 1.1 times, preferably at least 5 times, more preferably at least 10 times its weight in water. Also provided is a pharmaceutical composition comprising a PPRS, in particular a colon-specific PPRS.
Patent CA-2619408-A1 (CA)
Title: Water intake grill for personal watercraft
Inventor: CARLSON MORLEY RICHARD
IPC: B63H11/01
Filed: 2008-01-17
Abstract: A water intake grill for attachment to a water intake port of a jet watercraft. The water intake grill comprising a plurality of elongate members situated in between and mounted to fore and aft mounts. The fore mount comprising a base having an angularly orientated bottom surface for receiving and attaching first ends of the elongate members and an angularly orientated top surface for mounting atop thereof a singular key element having an overall geometric configuration substantially coinciding with the geometric configuration of a first inward socket integral to a forward wall section of the water intake port. The aft mount comprising a horizontally positioned base having rearward and forward sections, the rearward section having a primary key element in association with a cylindrical riser and the forward section having a secondary key element that extends across the width of the aft mount and includes an angular edge for receiving and attaching second ends of the elongate members. Each elongate member comprising a teardrop geometric profile incorporating an outward bottom section having a general rounded appearance and a tapered top end having sides commencing from an apex and extending angularly outward therefrom toward the outward bottom section, a geometric profile of which effectively reduces the amount debris into the water intake port while allowing continued passage of water into the water intake port to yield sustained operating performance of the jet watercraft and maintain effective cooling of the combustion engine generally associated therewith.
Patent CA-2620198-A1 (CA)
Title: Food additive for supplying mineral nutrients
Inventor: LAHRSOW JOBST
IPC: A23L29/00
Filed: 2006-08-23
Abstract: The invention relates to a food additive as a concentrated additive for supplying the human metabolism with mineral substances. The mineral substances are components of a salt-hydrate melt in an ionised form, and the salt-hydrate melt is a salt-water system, whereby the water content corresponds to the co-ordination number of the most hydrated ion.
Patent CA-2620199-A1 (CA)
Inventor: GRAHAM MORTON
IPC: F21K99/00
Filed: 2006-08-18
Abstract: A lamp comprising a base (10) having separate parts (11, 12) which may be brought together around, and to make contact with, an electrical supply cabl e (13). In the base (10) there is provided one or more LEDs and electrical circuitry, and a solid acrylic rod (18) is mounted in the base to receive light from the or each LED. The total internal reflection within the rod, an d the lensing effect of a domed upper end (19) produce a beam of light equivalent to a standard incandescent light bulb but with low power input an d increased durability when compared with an incandescent bulb. Several such lamps may be grouped together to form a downlighter, or spaced apart along t he supply cable (13) and mounted externally on a building for decoration and display purposes.
Patent CA-2620623-A1 (CA)
Inventor: MATTSSON THOMAS
IPC: H01F17/00
Filed: 2006-08-18
Abstract: A variable integrated inductor is described herein which has an inductance value that can be switched between two or more values. In the preferred embodiment, the variable integrated inductor includes a multi-loop primary inductor which is electromagnetically coupled to a pair of secondary inductors. The secondary inductors are connected to one another to form a closed circuit within which the secondary inductors have a changeable topology that can be switched between a series connection and a parallel connection in order to change an inductance value which is output by the multi-loop primary inductor. In one application, the variable integrated inductor is used in a voltage controlled oscillator (VCO) which is of the type that can be used in a multi-band RF radio transceiver (e.g., wireless communication device). In other applications, the variable integrated inductor can be used in a tuned amplifier load, an impedance matching network, a digitally controlled oscillator or any other type of frequency selective LC-network.
Patent CA-2623202-A1 (CA)
Title: Hydrazide compound and pesticidal use of the same
Inventor: IKEGAMI HIROSHI
IPC: A01N43/56
Filed: 2006-10-10
Abstract: A hydrazide compound represented by the formula (1): has excellent pesticidal activity.
Patent CA-2625054-A1 (CA)
Title: Apparatus and methods for vertebral augmentation
Inventor: DUTOIT CHRISTOF
IPC: A61B17/02
Filed: 2006-10-11
Abstract: The apparatus comprises elongated members (2200) which are inserted into vertebrae and secured to an arcuate fixation rod (2300) by clamps (2400) which when moved along the rod cause the elongated members and attached vertebrae to pivot. The method may further include passing through a cannula (2100) and into the a damaged vertebra a disruption tool for fracturing the damaged vertebral body. Once the cortical bone is broken or otherwise disrupted, the height of the damaged vertebral body may be restored, for example by removing the disruption tool and inserting through the cannula another tool, implant, device and/or material to restore the height of the vertebral body and to restore normal spinal curvature in the affected area. Grafting material or filler may be added with or without an implanted device to augment the damaged vertebral body.
Patent CA-2626215-A1 (CA)
Title: Tetrahydroquinolines, synthesis thereof, and intermediates thereto
Inventor: FEIGELSON GREGG B
IPC: C07D221/16
Filed: 2006-10-16
Abstract: The present invention relates to methods for synthesizing compounds useful as 5HT2C agonists or partial agonists, derivatives thereof, and to intermediates E thereto.
Patent CA-2626965-A1 (CA)
Inventor: NAIR VIJAY
IPC: C10G1/02
Filed: 2006-10-20
Abstract: The invention provides methods for producing crude products that includes producing formation fluid from a subsurface in situ heat treatment process;  separating the formation fluid to produce a liquid stream and a first gas stream, fractionating the liquid stream to produce one or more crude products, and catalytically cracking the crude product having the boiling point above 343 ~C to produce one or more additional crude products. The first gas stream may include olefins. At least one of the produced crude products has a boiling point above 343 ~C and at least one of the additional crude products is a second gas stream. The first gas stream may include olefins. At least one of the crude products has a boiling point above 343 ~C and/or least one of the additional crude products is a second gas stream.
Patent CA-2629080-A1 (CA)
Inventor: HIMBER JACQUES
IPC: A61P7/00
Filed: 2006-11-06
Abstract: The invention is concerned with novel pyrrolidine derivatives of formula (I) wherein X, Y, R1, R2 and R3 are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. These compounds inhibit the coagulation factor Xa and can be used as medicaments.
Patent CA-2629846-A1 (CA)
Title: Regeneration trolley
Inventor: SPERANZA ANGELO
IPC: A47J39/00
Filed: 2006-11-29
Abstract: A regeneration unit characterised by: a housing (11); a compartment (21) in the housing divided into two working volumes (22, 23) separated by a partition (24) whose position within the compartment (21) can be varied so as to vary the relative sizes of the two working volumes (22, 23); and a control means whereby a flow of air can be directed into each working compartment independently so that the temperature level and time of heating or cooling of material contained in one working volume (22, 23) is independent of temperature level and time of heating or cooling of material contained in the other working volume (23, 22). Typically the unit is further characterised in that each working volume (22, 23) is incorporated in a closed flow path which incorporates: means (26, 27) for displacing air around the flow path; and heat transfer means for heating or cooling air displaced around the flow path.
Patent CA-2631682-A1 (CA)
Title: Chemical composition useful as corrosion inhibitor
Inventor: GUZMANN MARCUS
IPC: C23F11/173
Filed: 2006-11-29
Abstract: The present invention relates to a chemical composition comprising (a) a glycoside component A comprising at least one glycoside of the formula R(OG)x wherein R is an aliphatic hydrocarbon radical having 1 to 25 carbon atoms or is a radical of formula R1(OR2)m which does not have more than 25 carbon atoms and wherein n = 0 to 24 and R1 and R2 are aliphatic hydrocarbon radicals; G is the residue of a saccharide moiety selected from the group consisting of fructose, glucose, mannose, galactose, talose, gulose, allose, altrose, idose, arabinose, xylose, lyxose, ribose and alkoxylated derivatives thereof; and x is 1 to 30; (b) an aspartate component B comprising at least one polymerisation product of aspartic acid, optionally in form of a copolymerisate with fatty acids, polybasic carboxylic acids, anhydrides of polybasic carboxylic acids, polybasic hydroxycarboxylic acids, monobasic polyhydroxycarboxylic acids, alkoxylated alcohols, alkoxylated amines, amino sugars, carbohydrates, sugar carboxylic acids and polymers thereof. The invention further relates to the use of such chemical compositions as corrosion inhibtor.
Patent CA-2632373-A1 (CA)
Title: Forced air flow electric shoe dryer
Inventor: BECKETT JOEL
IPC: A47L23/20
Filed: 2008-05-28
Abstract: A small, portable electric shoe dryer that includes and elongated, narrow outer housing with three longitudinally aligned heating elements and a fan and motor assembly mounted on one end. Formed on the outer housing and around the fan and motor assembly is a fan vent opening. Formed on the opposite, distal end of the outer housing is a plurality of front and side body vent openings. In one embodiment, a three pole manual switch is mounted inside outer housing with connects to the fan and motor assembly which draws dry air into the shoe from the top opening or forces moist air out of the shoe. In another embodiment, a pair of longitudinally aligned, upward extending wing elements are formed on the top surface which maintains an air space when the inside of the shoe is adjacent to the top surface.
Patent CA-2632665-A1 (CA)
Title: Mixing nozzle
Inventor: MCNAMEE PETER F
IPC: B67D1/00
Filed: 2005-12-12
Abstract: A beverage dispenser provides numerous inventive features in its refrigeration system, diluent delivery system, concentrate delivery system, mixing and dispensing system, and control system. The refrigeration system employs a plate heat exchanger to provide on demand refrigeration of an intermittent water flow. The diluent delivery system includes a flowmeter/solenoid/check-valve assembly. The concentrate delivery system employs a positive displacement pump. The mixing and dispensing system includes a mixing nozzle that has a locking feature such that an elevated blocking surface directly faces the inlet of pressurized diluent to create turbulence. The control system receives package-specific information from a scanner and diluent flow rate information from the flowmeter, and then determines the pump speed in order to set a desired mix ratio.
Patent CA-2633680-A1 (CA)
Title: Modeling the three-dimensional shape of an object by shading of a two-dimensional image
Inventor: HERKEN ROLF
IPC: G06T15/50
Filed: 2006-12-20
Abstract: System for generating a geometrical model representing a portion of a three-dimensional object by shading by an operator in connection with a two-dimensional image of the object, the image representing the object as projected onto an image plane, comprising receiving shading information, updating a geometric model, displaying the updated geometric model, and operat-ing on input of a hierarchical subdivision, polygon mesh, or NURBS  surface.
Patent CA-2634066-A1 (CA)
Inventor: TORRES ANTHONY R
IPC: G01N33/53
Filed: 2006-12-13
Abstract: Thin-film biosensor chips for detecting a target analyte in a biological sample are disclosed. The chips include a solid substrate, an antireflective optical layer, an attachment layer using a non-polymeric silane, and an Fc-specific binding molecule coupled to the non-polymeric silane. Kits containing the chips and methods of using and making the chips are also disclosed.
Patent CA-2634091-A1 (CA)
Inventor: MALZBENDER RAINER M
IPC: G09G3/34
Filed: 2006-12-19
Abstract: A direct-view display includes an array of MEMS light modulators and a control matrix formed on a transparent substrate, where each light modulator can be driven into at least two states, and a controller for controlling the states of each light modulator in the array. The control matrix transmits data and actuation voltages to the array. The controller includes an input, a processor, a memory, and an output. The input receives image data encoding an image frame for display. The processor derives a plurality of sub-frame data sets from the image data, where each sub-frame data set indicates desired states of light modulators in multiple rows and multiple columns of the array. The memory stores the plurality of sub-frame data sets. The output outputs the plurality of sub-frame data sets according to an output sequence to drive light modulators into the states indicated in the sub-frame data sets.
Patent CA-2635524-A1 (CA)
Inventor: FEWS ROBERT CLIVE
IPC: B32B18/00
Filed: 2008-06-20
Abstract: A fiber-reinforced, organic matrix, composite structural member includes a plurality of layers of fiber-reinforced, organic matrix, composite material in which adjacent layers are bonded to one another, wherein the structural member exhibits a non-linear stress-strain response when mechanically loaded to failure. A  helicopter landing gear includes a pair of skids and one or more cross members extending between the pair of skids. The one or more cross members includes a plurality of layers of fiber-reinforced, organic matrix, composite material in which adjacent layers are bonded to one another, wherein the cross members exhibit non-linear stress-strain responses when mechanically loaded to failure.
Patent CA-2636117-A1 (CA)
Title: Underwater equipment recovery
Inventor: NICHOLLS JONATHAN HARVEY
IPC: B63C7/02
Filed: 2006-12-21
Abstract: An apparatus and method for recovering equipment from within a body of water.  The apparatus comprises a frame supporting a mesh and an engagement element.  The engagement element is shaped to co-engage with the mesh and is attached to the equipment to be recovered prior to its deployment. Following deployment of the equipment, its recovery can be effected by lowering the mesh supported by the frame onto the equipment to cause the engagement element and the mesh to co-engage. The frame and mesh may then be lifted to the surface of the water bringing the equipment with them. Recovery may include searching for the equipment by monitoring a load associated with the frame and the mesh as it is lowered and raised at different locations, whereby an appropriate increase in load is taken to indicate that the equipment has become attached to the mesh.
Patent CA-2636341-A1 (CA)
Inventor: ADAMS CHRISTOPHER
IPC: H01H25/06
Filed: 2006-12-21
Abstract: In order to develop an electrical switching and/or actuating element (1) having a rotary switch (4) as the handle in such a way that it can be used with greater versatility, in particular allows for feedback in the form of outputting information items to the user, the invention proposes arranging a visual display device (8) for displaying at least two different symbols in the rotary switch (4).
Patent CA-2636601-A1 (CA)
Title: Novel melatonin ligands having antidepressant activity as well as sleep inducing properties
Inventor: LUCINI VALERIA
IPC: A61P25/24
Filed: 2007-01-12
Abstract: Novel melatonin ligands of Formula (I) or pharmaceutically acceptable salts thereof wherein: n is 1 or 2; m is 0, 1 or 2; p is 0, 1, 2, 3, 4, 5, 6, 7 or 8; v is 2 or 3; A is aryl or heteroaryl; Z is O, S or NR8;Y is selected from the group consisting of hydrogen, aryl, heteroaryl, CrC6 alkyl, C3-C6 cycloalkyl, and R is selected from the group consisting of hydrogen, hydroxyl, -OCF3, CF3, C1-C8 alkyl, C1C8 alkyloxy, C1C8 alkylthio, halogen and -Z-(CH2)P-A; R1 is selected from the group consisting of C1C4 alkyl, C3-C6 cycloalkyl, CF3, hydroxy-substituted C1C4 alkyl, hydroxy-substituted C3-C6 cycloalkyl, and NHR5, wherein R5 is C1C3 alkyl or C3-C6 cycloalkyl; R2 is selected from the group consisting of: hydrogen, C1C4 alkyl, C1C4 alkyloxy, OCF3, CF3, hydroxyl, and halogen; R3 is selected from the group consisting of hydrogen, C1C4 alkyl, C1C4 alkyloxy, OCF3, CF3, hydroxyl, and halogen; R and R3 may be connected together to form an -0-(CH2)v bridge representing with the carbon atoms to which they are attached a 5- or 6-membered heterocyclic ring system; R4 is selected from the group consisting of hydrogen, C1C4 alkyl, C1C4 alkyloxy, OCF3, CF3, hydroxyl, and halogen; R6 is selected from the group consisting of hydrogen and C1C6 alkyl; R7 is selected from the group consisting of hydrogen, C1C4 alkyl, C1C4 alkyloxy, OCF3, CF3, hydroxyl, and halogen; and R8 is selected from the group consisting of hydrogen and C1C4 alkyl.
Patent CA-2636764-A1 (CA)
Title: Sock
Inventor: LAMBERTZ BODO W
IPC: A41B11/00
Filed: 2007-01-10
Abstract: The invention relates to a sock, especially for use in sports activities. Said sock consists of a shaft and a foot part having a toe and a heel area and a contact area between the toe and heel area, and is provided with a bandage.  Said bandage (3) has a conical shape.
Patent CA-2636892-A1 (CA)
Inventor: BLANCHARD-DESCE MIREILLE
IPC: C09K11/06
Filed: 2007-01-10
Abstract: Fluorescent chemical compound composed of an n-generation dendrimer, n being a non-zero integer, exhibiting: - at least one central nucleus (N) with a valency of m, selected from the group consisting of - at least one first, non-chromophoric unit (X) with a valency of m', and - at least one second unit (Y) which exhibits two-photon absorption properties, with a valency of m''.
Patent CA-2637023-A1 (CA)
Title: Shorts comprising a waistband with self-gripping strip
Inventor: BEVEN YANNICK
IPC: A41D1/089
Filed: 2008-07-04
Abstract: Shorts comprising a rear face and a front face (10, 12) having a fly (18). The shorts further include a waistband (20) integral with the front and rear faces, the waistband extending between first and second ends (20a, 20b) placed on either side of the fly.   A tab (22) extends the first end (20a) as far as a free end (23) and is placed so as to cover the second end (20b) of the waistband. The tab has a self-gripping strip (24) placed facing a complementary self-gripping strip integral with the second end (20b) of the waistband.   A lace (29) connects the tab (22) to the second end (20b) of the waistband and passes through two respective holes (30, 32) made in the second end (20b) of the waistband so as to be able to be tied on the inside of the waistband.