baber/WOPTO huggingface dataset:
Patent EP-0653936-B1 (EP)
Inventor: HUDSON ALAN THOMAS
IPC: A61K31/122
Filed: 1993-08-06
Granted: 1997-07-16
Abstract: PCT No. PCT/GB93/01669 Sec. 371 Date Jan. 31, 1995 Sec. 102(e) Date Jan. 31, 1995 PCT Filed Aug. 6, 1993 PCT Pub. No. WO94/03163 PCT Pub. Date Feb. 17, 1994The present invention relates to the use of 2-[4-(4-chlorophenyl)cyclohexyl]-3-hydroxy-1,4-naphthoquinone or a physiologically acceptable salt or other physiologically functional derivative thereof for the manufacture of a medicament for the treatment of tumours in animals, to pharmaceutical compositions for the treatment of tumours in animals, to pharmaceutical compositions for the treatment of tumours, comprising said compound as active ingredient and to a method of treating tumours in an animal which comprises administering to said animal an effective amount of said compound.
Patent EP-0636063-B1 (EP)
Inventor: MEIDHOF HELMUT
IPC: B29C48/05
Filed: 1994-02-08
Granted: 1998-04-29
Abstract: PCT No. PCT/EP94/00361 Sec. 371 Date Dec. 16, 1994 Sec. 102(e) Date Dec. 16, 1994 PCT Filed Feb. 8, 1994 PCT Pub. No. WO94/19169 PCT Pub. Date Sep. 1, 1994.The invention concerns a closable extrusion nozzle for thermoplastic materials, with a nozzle plate (4) containing nozzles permitting the extrusion of the thermoplastic material from a hopper (1) and with a perforated plate (7), disposed upstream of the nozzle plate, whose apertures (8) can be brought in and out of alignment with the nozzles by displacing the perforated plate (7) with respect to the nozzle plate (4). The nozzle plate (4), which is U-shaped in cross-section, with the arms of the U at right angles to the direction of displacement of the perforated plate, is designed as a housing for the perforated plate (7) enclosed within it. A sealing surface (15) on the perforated plate (7) rests against the flat housing floor (5) in which the nozzles (6) are located, there being a gap between the perforated plate (7) and the housing at least in the curved regions (16, 17) of the floor, and the region in which the seal is formed by the sealing surface (15) resting against the floor (5) being limited to a narrow zone round the nozzles (6).
Patent EP-0690843-B1 (EP)
Inventor: ANDERSSON BENGT RONNY
IPC: C07D209/60
Filed: 1994-03-21
Granted: 2000-08-30
Abstract: PCT No. PCT/US94/02800 Sec. 371 Date Sep. 7, 1995 Sec. 102(e) Date Sep. 7, 1995 PCT Filed Mar. 21, 1994 PCT Pub. No. WO94/21608 PCT Pub. Date Sep. 29, 1994A compound of formula (I) and pharmaceutically acceptable salts thereof, where Z is R3 and X and Y form (a), or X is R3 and Y and Z form (a) or (b); R1 and R2 are independently hydrogen, C1-6 alkyl, C3-7 cycloalkyl, -CH2-C3-7 cycloalkyl, phenyl (optionally substituted with halogen or C1-6 alkyl), -thiophenyl (optionally substituted with halogen or C1-6 alkyl), or C1-6 alkyl phenyl; R3 are independently hydrogen, halogen, -O-C1-6 alkyl or C1-6 alkyl; R4 is a valence bond, CH2 or oxygen; R5 and R6 are independently hydrogen, sulfur, -S-C1-6 alkyl, halogen, CON(R3)2, -COCF3, -CO-C1-6 alkyl, -CO phenyl, oxygen, -CHO, CN except that when Y and Z form (b), R1 and R2 are hydrogen or a C1-6 alkyl and R3 is hydrogen, then at least one of R5 and R6 must be other than hydrogen. These compounds and derivatives thereof exhibit dopamine-receptor stimulating activity in mammals.    <IMAGE>  (I)   <IMAGE>  (a)   <IMAGE>  (b)
Patent EP-0691982-B1 (EP)
Inventor: NILSSON BIRGITTE MAHLER
IPC: C12N9/00
Filed: 1994-03-29
Granted: 1998-09-16
Abstract: PCT No. PCT/DK94/00132 Sec. 371 Date Sep. 7, 1995 Sec. 102(e) Date Sep. 7, 1995 PCT Filed Mar. 29, 1994 PCT Pub. No. WO94/22903 PCT Pub. Date Oct. 13, 1994The present invention relates to a method of separating an enzyme from an aqueous solution comprising this enzyme in mixture with other proteins, and recovery of the desired enzyme on crystalline form.
Patent EP-0653455-B1 (EP)
Inventor: MATSUMURA SHUNICHI
IPC: C08L69/00
Filed: 1994-05-18
Granted: 1997-10-01
Abstract: On décrit un film de doublage de tôles métalliques obtenu soit à partir d'une résine de polycarbonate présentant une forte concentration terminale en hydroxyle, soit à partir d'une composition comprenant ladite résine et une résine de polyester; on décrit également un film de doublage de tôles métalliques obtenu par stratification dudit film et d'un film de polyester. Ce film de doublage présente d'excellentes propriétés d'adhérence sur des tôles métalliques, d'aptitude au moulage, de thermorésistance, de résistance aux traitements en autoclave, de retenue d'arôme, de résistance aux chocs et la formation de bosses, et d'aptitude au traitement en vue de produire des boîtes-boisson métalliques, par exemple, par étirage ou repassage.
Patent EP-0706559-B1 (EP)
Inventor: CHRISTIE JULIE ANN
IPC: C11D3/18
Filed: 1994-06-30
Granted: 2001-08-08
Abstract: There is provided a bleaching composition, suitable for use in a machine dishwashing method, containing: an oxygen-releasing bleaching agent, from 0.05 % to 2.5 % by weight, preferably 0.1 % to 0.6 % by weight of a paraffin oil, from 0.005 % to 3 %, preferably from 0.02 % to 1 % and most preferably from 0.05 % to 0.5 % by weight of a benzotriazole compound. Preferably the bleaching composition forms part of a detergent composition.
Patent EP-0714271-B1 (EP)
Inventor: REIMER LOTTE
IPC: A61F5/37
Filed: 1994-08-19
Granted: 1998-05-13
Abstract: PCT No. PCT/DK94/00311 Sec. 371 Date Nov. 7, 1994 Sec. 102(e) Date Nov. 7, 1994 PCT Filed Aug. 19, 1994 PCT Pub. No. WO95/05790 PCT Pub. Date Mar. 2, 1995A device for prevention of involuntary urination in a female has an elastic body (21) designed for arrangement in the vagina for compressive action on and support of the neck of the bladder. The body (21) is made of a compressible material and comprises at least two projecting legs (23) joined in a flexible base (22) and is dimensioned in such a way that in the non-deformed state of the body of the longest distance between the free ends of at least two legs exceeds the distance between the anterior wall and the posterior wall of the vagina. After the insertion of the body into the vagina in an elastically deformed stated with the legs bent in a direction towards each other, an active pressure is thus exerted on the bladder neck. On their mutually facing sides, the legs are designed in such a way that in the elastically deformed insertion state they come into mutual contact for the provision of an increased elastic force of restitution. An applicator for insertion of the device includes an elongated member having a proximal end and a substantially rod-shaped distal end portion for abutment with a bevel or a recess (24) formed in the angle between the legs of the device.
Patent EP-0726727-B1 (EP)
Inventor: MCCARTNEY ANTHONY JOHN
IPC: A61B1/31
Filed: 1994-10-13
Granted: 2004-04-21
Abstract: A transvaginal tube (10) adapted for insertion into the vaginal tract of a patient, the tube (10) having a diameter greater than the patient's cervix opening and having a distal end (14) and a proximal end (12), the proximal end (12) being cut in a plane non-normal to the tubular axis and being adapted to define the patient's cervico-vaginal junction (24).
Patent EP-0667369-B1 (EP)
Inventor: BASTIOLI CATIA
IPC: C08L31/04
Filed: 1995-01-26
Granted: 2002-06-12
Abstract: Expanded articles of biodegradable plastic material are produced by agglomerating expanded particles with density from 0.1. to 0.003 g/gm<3> and size from 0.5 to 10 mm of diameter, made of a material comprising:  from 50 to 95% by weight of thermoplastic starch; from 0.5. to 45% by weight of at least one thermoplastic polymer; from 2 to 20% by weight of water;  characterized in that the foamed particles are prepared through a route which consists of compressing/depressurising non foamed particles or through a heating treatment by microwave. <IMAGE>
Patent EP-0658538-B1 (EP)
Inventor: TUTTLE RONALD RALPH
IPC: C07C237/30
Filed: 1989-02-17
Granted: 1997-10-29
Abstract: Methods and devices for the diagnosis, evaluation and treatment of coronary artery disease (CAD) by means of a closed loop drug delivery system that delivers a catecholamine exercise simulating agent, some of which are novel, which elicit both acute and adaptive cardiovascular responses similar to those elicited by aerobic activity are provided. The acute responses to the exercise simulating agent are used to diagnose and evaluate CAD in lieu of the acute responses to aerobic exercise. Due to their adaptive responses these compounds may be used to treat CAD in lieu of the adaptive responses caused by aerobic exercise training or to treat other conditions which the adaptive responses caused by aerobic exercise are desirable.
Patent EP-0677857-B1 (EP)
Inventor: CHWIERALSKI ALFRED DR-ING DIPL
IPC: H01H9/02
Filed: 1995-03-16
Granted: 1997-11-05
Abstract: An electrical switch of a type having a detector probe with a sensor and a mounting, includes a housing having a bottom and a top which are detachably connected together solely by complementary locking elements. The mounting of the detector probe is rotatably supported in the top via a trunnion and secured by a fixture. Snapped onto the top is a cover which secures, partly via the fixture, the locking elements in their locking position and also secures the fixture in place, to thereby attain an assembly of the components of the switch without resorting to the use of screw fasteners.
Patent EP-0687644-B1 (EP)
Inventor: HEIKKINEN URHO
IPC: B66B9/04
Filed: 1995-06-13
Granted: 2002-02-06
Abstract: The invention relates to a suspension arrangement for a hydraulic elevator. Besides a normal diverting pulley (8) mounted on the top end of the piston (7), the arrangement comprises an additional diverting pulley (9) placed at the bottom end of the cylinder (5). The first end (10) of the elevator ropes (3) is fixed to a rope anchorage (11) in the car frame (4,15,19) of the elevator, from where the ropes are passed over the diverting pulley (8) on the top end of the piston to the additional diverting pulley (9), from which additional diverting pulley the ropes are further passed to an adapter (13) moving with the top end of the piston (7), the other end (12) of the ropes being attached to said adapter (13). <IMAGE>
Patent EP-0689791-B1 (EP)
Inventor: ARCHER JOHN
IPC: A47L15/42
Filed: 1995-06-20
Granted: 2000-02-02
Abstract: Hot cleansing liq. is collected in a tank (9) and pumped (8) through a pipe (101) into the intermediate tank (10) which is drained (22) via the heat exchanger (4), giving up its heat to the fresh water (23) entering through a quantity regulating valve (1). Front he top of the heat exchanger the preheated fresh water is additionally heated (5) before being pumped (6) to the sprays (7). Dirt is excluded from the collection tank (9) by a filter (91). An overflow (15) from the intermediate tank leads into the wastepipe downstream from the heat exchanger outlet valve (12). <IMAGE>
Patent EP-0709219-B1 (EP)
Inventor: SAKAKI MAMORU
IPC: D21H19/16
Filed: 1995-10-26
Granted: 2000-01-12
Abstract: A recording paper formed mainly from a fibrous material with a cationic substance applied onto the surface thereof or impregnated therein contains a non-wood fiber at least. An image forming method comprises forming an image on the recording paper through steps of developing an electrostatic image on a photosensitive member by a developing means with a toner, transferring the developed toner image from the photosensitive member onto the recording paper, and fixing the transferred toner image on the recording paper. An image forming method comprises forming an image on the recording paper by ink-jet recording by applying, onto the recording paper, droplets of an ink containing at least an acid dye and/or a direct dye, water, and a water-soluble solvent. <IMAGE>
Patent EP-0707830-B1 (EP)
Inventor: GUGLIELMI GUIDO
IPC: A61B18/14
Filed: 1995-10-16
Granted: 2001-02-28
Abstract: An apparatus is provided for electrocoagulating blood and tissue at an occlusion site by means of application of an alternating signal or current through a detachable coil (14) on the end of a microcatheter. A Guglielmi Detachable Coil (GDC) is preferably used in the combination with radio frequency energy to cause local heating at the coil. Once carbonization of blood at the detachment zone of the GDC coil occurs, the impedance of the entire system increases. The impedance increase is detected to automatically turn off the alternating current and then to apply a direct current to electrolytically detach the GDC coil from the microcatheter. <IMAGE>
Patent EP-0669131-B1 (EP)
Inventor: ANDRE FREDERIC
IPC: A61K9/08
Filed: 1995-02-02
Granted: 1999-04-28
Abstract: Concentrated aq. solns. contg. argatroban (II), one or more micelle-forming agents, esp. a cholic acid deriv. of formula (I), and one or more lipoids (III) esp. a phosphatide, are new. R1, R2, R3 = H, OH, or exocyclic keto; R4 = carboxy, opt. attached through an amide linkage to the amine of an amino acid. The steroid skeleton may further contain one or two double bonds.
Patent EP-0704448-B1 (EP)
Inventor: CLAUSSNER ANDRE
IPC: C07D491/107
Filed: 1995-09-28
Granted: 2001-12-05
Abstract: Imidazolidines of formula (I) in racemic, enantiomeric and diasteroisomeric forms, and their salts are new. In (I) ring is e.g. satd. heterocycle of 4-7 members contg. either O, N, S (opt. oxidised), and opt. substd. by a group selected from R3; Ar is e.g. aryl (opt. substd. by halo, CN, NO2, CF3, CF3O, OH, COOH or salified, esterified, or amidified COOH) or a gp. (ii) in which N is opt. oxidised and R1 and R2 are H or (substd.) alkyl, or form with N atom e.g. 5, 6 or 7 membered monocyclic ring opt. contg. other heteroatoms (O, N, S) and opt. substd. etc.; X is O or S; Y is O, S or NH; R3 is H, aryl, alkyl, alkenyl, alkynyl, opt. interrupted by one or more O, N, or S (opt. oxidised) atoms, and opt. substd.
Patent EP-0733093-B1 (EP)
Inventor: BAYENSE CORNELIS ROELAND
IPC: C11C3/10
Filed: 1994-12-06
Granted: 2001-06-27
Abstract: PCT No. PCT/NL94/00309 Sec. 371 Date Jun. 6, 1996 Sec. 102(e) Date Jun. 6, 1996 PCT Filed Dec. 6, 1994 PCT Pub. No. WO95/16014 PCT Pub. Date Jun. 15, 1995The invention relates to a process for the catalytic interesterification of triglycerides, which is characterized in that a heterogeneous catalyst is used, based on one or more oxides and/or oxysalts of metals of the groups IA and IIA of the Periodic System, at least one of the oxides and/or oxysalts having an optical basicity  LAMBDA  which is at least 0.5.
Patent EP-0731955-B1 (EP)
Inventor: KUNZMANN HUBERT
IPC: G06K9/03
Filed: 1994-10-04
Granted: 2002-02-06
Abstract: A process for the automatic detection and recognition of recorded information, especially inscription on documents, comprises comparing samples of the entered recorded information and the corresponding output recognition results, in which, depending on the result of comparison, the process parameters are changed in such a way that the results of recognition are optimised.
Patent EP-0733064-B1 (EP)
Inventor: THOMAS WAYNE R
IPC: C12N15/09
Filed: 1994-12-07
Granted: 2006-03-15
Abstract: Isolated nucleic acids encoding an allergen of Dermatophagoides pteronyssinus, Der p III, are disclosed. A cDNA encoding a peptide having a Der p III activity and a predicted molecular weight of about 24,985 daltons is also described. The nucleic acids can be used as probes to detect the presence of Der p III nucleic acid in a sample or for the recombinant production of peptides having an activity of Der p III. Peptides having an activity of Der p III can be used in compositions suitable for pharmaceutical administration or methods of diagnosing sensitivity to house dust mites.
Patent EP-0738272-B1 (EP)
Inventor: COHEN AHARON S
IPC: B01J20/26
Filed: 1995-01-04
Granted: 1997-11-05
Abstract: Disclosed is a substrate useful for separating unmodified and modified mononucleotides and oligonucleotides. The substrate includes at least 12% (weight:volume) polymer in at least 5M urea and at least 32% (volume:volume) organic solvent, the organic solvent being a chemically stable liquid at room temperature and having a dielectric constant of at least 20. Also provided is a method of separating unmodified and modified mononucleotides and/or oligonucleotides utilizing this substrate.
Patent EP-0741588-B1 (EP)
Inventor: HAMMARLUND NILS
IPC: A61M11/00
Filed: 1995-01-19
Granted: 1998-11-18
Abstract: The invention relates to a method of converting a medicament to a form which can be used for administration to the airways or respiratory tracts of a mammal, wherein a liquid which consists in or includes a medicament is transformed to an aerosol which includes small liquid particles, with the aid of a gas stream or with the aid of other means, and wherein the liquid particles are collected in the gas stream or in a gas stream respectively, and wherein the liquid particles are collected in a gas which contains helium and/or neon and preferably also oxygen. The invention also relates to the use of a helium-containing and/or neon-containing gas mixture for producing an aerosol and a medicament preparation in the form of an aerosol consisting in liquid particles which are comprised of or include a medicament, and a gas mixture that contains helium and/or neon.
Patent EP-0741540-B1 (EP)
Inventor: SCHNEIDER M BRET
IPC: G16H30/20
Filed: 1995-01-27
Granted: 2004-04-21
Abstract: Cette invention concerne un procédé et un appareil (2) permettant d'obtenir et d'afficher en temps réel une image d'un objet (10) obtenue par une modalité faisant en sorte que l'image corresponde à une ligne de vision établie par une autre modalité. Ce procédé comprend les étapes suivantes: on crée une banque (14) d'images à traiter de l'objet produites par une première modalité d'imagerie; on forme une banque (12) d'images principales produites par la deuxième modalité d'imagerie; on établit des références pour la banque d'images principales par rapport à la banque d'images à traiter; on obtient une image principale de l'objet en temps réel par la deuxième modalité d'imagerie le long d'une vue principale; on compare l'image principale en temps réel aux images principales stockées dans la banque d'images principales par analyse d'image numérique pour identifier une ligne de vue d'image à traiter correspondant à la vue principale en temps réel; on transforme l'image à traiter identifiée pour qu'elle corresponde à l'échelle, à la rotation et à la position de l'image principale; puis on affiche l'image à traiter transformée.
Patent EP-0760685-B1 (EP)
Inventor: GOVINDAN SEREGULAM V
IPC: C07K16/00
Filed: 1995-05-08
Granted: 2003-08-27
Abstract: A method of radiolabeling a protein with a radionuclide including contacting the protein with a protected tertiary thiol-containing bifunctional chelating agent that is capable of reacting with the protein at one end of the agent and is capable of complexing with a radionuclide at the other end of the agent, to form a protein-acetyl-t-thiol-containing conjugate. The protein-acetyl-t-thiol-containing conjugate then is deprotected and admixed with a reducing agent for the radionuclide, where the radionuclide is added in a subsequent step, to form a mixture of reducing agent and protein-t-thiol-containing conjugate. This mixture then is reacted with a radionuclide whereby the radionuclide reacts with pendant sulfhydryl groups present on the protein-t-thiol-containing conjugate. Methods of radioimmunotherapy and diagnostic kits suitable for forming a composition to be administered to a human patient also are disclosed.
Patent EP-0777471-B1 (EP)
Inventor: CROOKS STEPHEN L
IPC: A61P17/00
Filed: 1995-07-14
Granted: 2002-11-27
Abstract: A method of inhibiting leukotriene biosynthesis, involving administering a compound of formula (I) wherein M, R, R', R'', and n are as defined herein. Also, a pharmaceutical composition involving such a compound and the use of such compounds in the manufacture of a pharmaceutical composition for inhibiting leukotriene biosynthesis.
Patent EP-0789547-B1 (EP)
Inventor: GRAY JOHN MARTYN
IPC: G06K19/04
Filed: 1995-11-01
Granted: 2001-04-11
Abstract: A reading device in the form of a spring clip is adapted to be clipped onto a flat corner of a collapsible-bag passive reservoir for medicament. The reading device comprises mutually opposed gripping portions (16) urged together by a spring (19), whereby activation and receiving coils (22) encapsulated in recesses (21) in the gripping portions (16), can be located closely adjacent a data carrier device located at the corner of a collapsible bag filled with medicament, thereby to read medicament-related data recorded in the data carrier device. The data detected by the reading device can be relayed to a delivery device for controlling the flow of medicament from the collapsible bag.  <IMAGE>
Patent EP-0794707-B1 (EP)
Inventor: BOULEY CHRISTINE
IPC: A23C9/123
Filed: 1995-12-29
Granted: 1998-11-11
Abstract: A milk starter culture consisting of a mixture of three lactic acid bacteria, i.e. Streptococcus thermophilus DN-001 147, Streptococcus thermophilus DN-001 339, and Lactobacillus bulgaricus DN-100 182, is disclosed. Fermented dairy foods prepared by means of the starter defined above, and the uses of said starter and said fermented foods for preparing antidiarrhoeal products, are also disclosed.
Patent EP-0765791-B1 (EP)
Inventor: HIDEN HELMUT
IPC: B61F5/38
Filed: 1994-11-23
Granted: 1999-01-27
Abstract: The chassis has the individual wheel set supported by a chassis frame (50) acted on by a spring elastic device (6), providing a restoring force opposing the movement of the chassis frame when travelling around a curved track section. The chassis frame is attached to a yoke (58) via linkages (61,61') allowing its movement relative to the yoke in both vertical and transverse directions, with impact buffers (68,68') limiting the transverse movement.
Patent EP-0819320-B1 (EP)
Inventor: HAMMERSCHMIDT ALBERT
IPC: H01M8/1004
Filed: 1996-03-22
Granted: 1999-06-16
Abstract: PCT No. PCT/DE96/00497 Sec. 371 Date Aug. 27, 1997 Sec. 102(e) Date Aug. 27, 1997 PCT Filed Mar. 22, 1996 PCT Pub. No. WO96/31913 PCT Pub. Date Oct. 10, 1996A fuel cell with a proton-conducting membrane, on which catalyst material and a collector are arranged on both sides, is characterized by the following features: on the side facing the membrane (14), the collectors (16,18) are provided with an electrically conductive gas-permeable carbon aerogel with a surface roughness of <2  mu m; a catalyst layer (15, 17) of platinum or a platinum alloy is in each case applied to the carbon aerogel by material bonding; and a membrane (14), deposited by plasma-chemical means, with a layer thickness of between 3 and 50  mu m, is located between the catalyst layers (15, 17).
Patent EP-0821687-B1 (EP)
Inventor: CAPUDER EGIDIJ
IPC: A61P31/04
Filed: 1996-04-17
Granted: 2003-05-07
Abstract: Provided is a process for purification of clavulanic acid or a pharmaceutically acceptable salt or ester thereof, including adding an additional solvent to a solution of clavulanic acid in water immiscible solvent; contacting the solution with an amine; isolating the amine salt of the clavulanic acid formed; and converting the amine into clavulanic acid or a pharmaceutically acceptable salt or ester thereof.