baber/WOPTO huggingface dataset:
Patent CA-2362385-C (CA)
Title: Heterodiazinon compound
Inventor: NAGATO SATOSHI
IPC: C07D271/113
Filed: 2000-02-15
Granted: 2009-08-11
Abstract: The present invention provides a novel compound having an excellent 2-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptor antagonistic action, particularly a therapeutic, preventing and ameliorating action useful for cerebral ischemia, cerebrospinal injuries, Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, Huntington's chorea, epilepsy, pain, spastic paralysis, multiple sclerosis etc. That is, the present invention provides a heterodiazinon compound represented by the following formula (I), a pharmacologically acceptable salt thereof or hydrates thereof.     (see formula I) Wherein A represents an oxygen atom, a sulfur atom or a group represented by the formula >NR3 (wherein R3 represents hydrogen atom or a lower alkyl group);     R1 and R2 are the same as or different from each other and each represents an optionally substituted aryl group, an optionally substituted heteroaryl group, an optionally substituted aralkyl group, an optionally substituted heteroaryl alkyl group, an optionally substituted aryl alkenyl group, an optionally substituted heteroaryl alkenyl group, an optionally substituted piperidyl group, an optionally substituted piperazinyl group; a morpholinyl group, an optionally substituted lower cycloalkyl group, a tetrahydrofuranyl group, a tetrahydropyranyl group, an adamantyl group, an optionally substituted amino group or an optionally substituted amide group; and R4 and R5 are the same as or different from each other and each represents hydrogen atom, hydroxy, a halogen atom, nitrile group, nitro group, a lower alkyl group, an aryl group or a heteroaryl group, provided that the compounds represented by the following formula (II):   (see formula II) (wherein R11 and R12 are the same as or different from each other and each represents hydrogen atom, fluorine, chlorine, bromine, iodine, a C1-C2 fluoroalkyl group, a C1-C2 chloroalkyl group, a C1-C2 bromoalkyl group, a C1-C6 alkyl group, a C3-C6 cycloalkyl group, a C7-C9 aralkyl group, phenyl group, a C1-C6 alkoxy group, a C1-C6 alkylthio group, a C1-C6 alkylsulfinyl group, a C7-C9 aralkoxy group, phenoxy group, phenylthio group, phenylsulfonyl group, alkali metal carboxylate C2-C5 alkoxycarbonyl group or a group represented by the formula -N(R15)R16 (wherein R15 and R16 are the same as or different from each other and each represents hydrogen atom or a C1-C2 alkyl group); and R13 and R14 are the same as or different from each other and each represents a C1-4 alkylsulfonyl group, nitro group, a group represented by the formula -OCH n X3-n (wherein X represents fluorine, chlorine, bromine or iodine; and n is any of integers 1 to 3) or a group having the same meanings as the definitions of R11 and R12) are excluded.
Patent CA-2366383-C (CA)
Title: A helically wound guidewire
Inventor: KLINT HENRIK SONDERSKOV
IPC: A61M25/01
Filed: 2000-03-29
Granted: 2007-11-27
Abstract: A guidewire comprising a distal end (2), a shaft portion (4) and a proximal end (3), wherein the shaft portion comprises a single helically wound, ribbon-shaped wire (7) having a pitch angle a in the range of 35° to 76°, and said helical wound wire preferably has a smaller total outer diameter at the distal end than at its proximal end.
Patent CA-2369054-C (CA)
Inventor: STONE RICHARD A
IPC: A61K31/445
Filed: 1990-06-14
Granted: 2006-10-24
Abstract: A composition for the inhibition of the abnormal postnatal axial growth of the eye of a maturing animal which comprises a pharmaceutically effective amount of a muscarinic pharmacological antagonist relatively selective for blocking the cholinergic receptos in cells of the brain, neural tissue and/or neural ganglia but less selective for blocking the cholinergic receptors of the cells of smooth muscles at the front of the eye, said antagonist present in a carrier or diluent suitable for ocular administration. A suitable antagonist is pirenzepine. Other suitable antagonists are telenzepine and o-methoxy-sila-hexocyclium.
Patent CA-2369337-C (CA)
Inventor: GUERET JEAN-LOUIS H
IPC: A45D34/00
Filed: 2002-01-28
Granted: 2006-07-18
Abstract: La présente invention concerne un dispositif (10) pour le conditionnement et l'application d'un produit notamment cosmétique comprenant une première partie (20), et une seconde partie (30) qui, dans une position de fermeture, délimite avec la première partie, un volume fermé (50), ladite seconde parti e (30) étant solidaire d'un applicateur (40) au moins en partie compressible e t apte à absorber ledit produit, ledit applicateur (40) étant configuré de sor te que, dans ladite position de fermeture, il soit, au moins en partie, comprimé à l'intérieur dudit volume fermé (50), et puisse, à chaque ouverture du dispositif, après qu'il se soit détendu, contenir sensiblement tout le produit condition né dans ledit dispositif (10).
Patent CA-2374635-C (CA)
Title: Sulfuric acid mono-[3-({1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-4-yl}-hydroxy-methyl)-2-methoxy-phenyl]ester
Inventor: BERNOTAS RONALD CHARLES
IPC: A61P43/00
Filed: 2000-07-13
Granted: 2007-04-17
Abstract: The present invention is directed to sulfuric acid mono-[3-({1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-4-yl}-hydroxy-methyl)-2-methoxy-phenyl]ester having the Formula I:      a metabolite of the 5HT1A antagonist (+)-.alpha.-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol and a process for its preparation and its use in the treatment for a number of disease states.
Patent CA-2375970-C (CA)
Inventor: ROE DONALD C
IPC: A61B5/20
Filed: 2000-06-29
Granted: 2005-07-05
Abstract: A disposable article (20) to be fitted to a wearer. The disposable article (20) preferably comprises a sensor (60) operatively connected to the article. The sensor (60) is adapted to detect electrical activity in the wearer's smooth colonic muscles abdominal muscles or the muscles surrounding the bladder or rectum which correlates to an impending elimination of bodily waste and to provide a signal to the wearer, a caregiver or an element o1 the article of the impending event.
Patent CA-2376281-C (CA)
Title: Visually-directed surgical instrument and method for treating female urinary incontinence
Inventor: MILLER GARY H
IPC: A61B19/00
Filed: 2000-06-01
Granted: 2008-07-29
Abstract: Described is a surgical instrument, and method for treating female urinary stress incontinence. The instrument includes a curved needle-like element (10) defining in part a curved shaft (18) having a distal end (17), and a proximal end (19). A tape (12) attaches to the needle (10) for implanting into the lower abdomen of a female to provide support to the urethra. The needle (10) defines an inner lumen (100) for passage of optical devices, and/or fluids. A surgical optical system may interface directly with the needle, or alternatively, the needle hand piece or handle may be modified to accept the optical system. The tip of the needle is also modified to contain a window or viewing port that allows for the transmission of light from the ambient target tissue into the imaging lens of the optical system. The optical system allows the surgeon to maintain continuous anatomic visualization during introduction, and navigation of the needle within the lower abdomen.
Patent CA-2377145-C (CA)
Inventor: MARCOLINI DARLENE A
IPC: A23L13/40
Filed: 2000-06-26
Granted: 2005-10-18
Abstract: A mixed sodium-potassium polyphosphate glass with a high potassium to sodium ratio and a low level of insoluble material and a method for its production are disclosed. The polyphosphate glass is used in reduced sodium foods, especially beverages and meat products. The polyphosphate has the formula (K,Na)(n+2)O(PO3)n, in which the ratio of potassium to sodium is about 0.5 to 3.8; the average value of n is greater than 10; and at least 85 % of the phosphate species comprise more than three phosphate units. The material contains less than 10% by weight insoluble material.
Patent CA-2379469-C (CA)
Inventor: COLGROVE JAMES R
IPC: B07B1/42
Filed: 2002-03-27
Granted: 2010-06-15
Abstract: A vibratory screening machine having a single vibratory motor mounted on its inner resiliently mounted frame by motor mounting structures at its ends, each motor mounting structure consisting of a combination of a fist bracket carrying a directionally stiff bushing with the fist bracket being mounted in a motor mount bracket with the fist bracket having a first cutaway portion positioned within a second cutaway portion in a rib on the base of the motor mount bracket. The directional stiffness of each bushing is aligned with the center of rotation of the vibratory motor, and this will produce linear motion when the unbalance of the vibratory motor is in line with the center of rotation of the motor and the direction of the directional stiffness of the bushings.
Patent CA-2396734-C (CA)
Title: Extraction of flavonoids
Inventor: BURONG WILLFRITS GERALD
IPC: A61P31/04
Filed: 2001-01-11
Granted: 2009-03-31
Abstract: A method of producing an enriched flavonoid aglycone extract from starting material containing a suitable flavonoid glycoside and/or conjugate thereof comprising the steps of: (i) enzymatically converting the flavonoid glycoside or conjugate thereof into the flavonoid aglycone; (ii) adjusting the pH to render the flavonoid aglycone soluble and removing the insoluble fraction; and (iii) adjusting the pH to render the soluble flavonoid aglycone relatively insoluble and forming an extract containing the same.
Patent CA-2403925-C (CA)
Inventor: LAWSON CRAIG
IPC: A61M27/00
Filed: 2001-04-04
Granted: 2008-09-16
Abstract: Cette invention se rapporte à un système de retrait de matière intraluminale, qui comprend un ensemble de coupe (50) pouvant être placé dans la lumière du passage corporel chez un sujet mammifère et qui est raccordé en mode opérationnel à des commandes (14) du système. Un tel ensemble de coupe composite (50) comprend un couteau de diamètre fixe distal (52) et un couteau de diamètre réglable proximal (54). Cet ensemble de coupe peut progresser axialement par translation de l'arbre d'entraînement et il peut tourner par rotation de l'arbre d'entraînement. Le couteau réglable (54) peut être réglé entre une configuration de petit diamètre et une configuration de grand diamètre, par rotation de l'arbre d'entraînement dans des directions opposées. Le couteau peut ainsi être introduit et retiré du site de retrait de matière dans une configuration repliée de petit diamètre qui facilite les mouvements de translation et de navigation du dispositif dans divers passages corporels. Le couteau réglable (54) peut être déployé sélectivement au niveau du site de retrait de matière, pour faciliter la découpe, le retrait et l'aspiration de la matière occlusive.
Patent CA-2407768-C (CA)
Inventor: UCHIYAMA KAZUNAO
IPC: B62D65/00
Filed: 2001-05-01
Granted: 2008-10-14
Abstract: A car side panel assembly line capable of increasing a productivity by shortening an operation time and having a set station ST2, a welding station ST3, and a next operation station ST4 disposed in series in this order, comprising a set carriage 91 having, thereon, a set jig 91 capable of holding the side panel W in upright attitude from the side and installed reciprocatingly between the set station ST2 and the welding station ST3 and a frame carriage 8 1 having a lower frame 80 and an upper frame 81, capable of holding, between both frames 80, 81, the side panel W in upright attitude through clamp members (82 1, 82 2, 82 3, 83 1, 83 2, 83 3) mounted on the frames 80, 81, installed reciprocatingly between the welding station ST3 and the next operation station ST4, and allowing to exchange the side panel W with the set carriage 9 1.
Patent CA-2408532-C (CA)
Title: Method and apparatus for unique address assignment, node self-identification and topology mapping for a directed acyclic graph
Inventor: OPRESCU FLORIN
IPC: G06F13/00
Filed: 1993-12-16
Granted: 2005-07-26
Abstract: A node identification system is described for use in a computer system in which the various components of the system are interconnected via nodes on a communications bus. Once the topology of the nodes has been resolved into an acyclic directed graph, each node may be assigned a non-predetermined unique address. Each node having a plurality of ports has an a priori assigned priority for port selection. Each child node connected to a parent is allowed to respond in the predetermined sequence depending upon the port through which it is connected to its parent.      Each node in the graph will announce its presence according to its location in the graph. Each receives an address incremented from the previous addresses assigned, thereby insuring uniqueness. The same mechanism may be implemented to allow each node in turn to broadcast information or the bus concerning the parameters of its local host. Likewise, additional information may be conveyed from each node concerning connections to other nodes thereby allowing a host system to generate a map of the resolved topology including any information about disabled links which may be used for redundancy purposes.
Patent CA-2413392-C (CA)
Inventor: WIECHERS JONATHAN T
IPC: F16K5/06
Filed: 2002-12-03
Granted: 2010-11-02
Abstract: A packing assembly, retrofit kit, and check valve with adjustable lift having a ball stop member having opposed first and second contact portions and at least two washers being provided in a stacking configuration. The stacking configuration is one selected from one in which all of the at least two washers are stacked against the first contact portion of the ball stop member, one in which all of the at least two washers are stacked against the second contact portion of the ball stop member, and one in which at least one of the at least two washers is stacked against the first contact portion of the ball stop member and at least one of the at least two washers is stacked against the second contact portion of the ball stop member. Preferably, the at least two washers are of different thicknesses with, more preferably, the thicknesses of the at least two washers being multiples of each other. Most preferably, the at least two washers are a first washer and a second washer with the second washer having a thickness that is twice the thickness of the first washer.
Patent CA-2413755-C (CA)
Inventor: NISHIKITA YUKINOBU
IPC: B65G15/36
Filed: 2001-06-13
Granted: 2009-12-08
Abstract: L'invention concerne une bande de renforcement longue durée destinée à des transporteurs à courroie. On forme une bande de renforcement (3) en entrelaçant un certain nombre de cordes dures (6) s'orientant dans une direction orthogonale par rapport à une direction longitudinale et étant espacées de façon longitudinale à des intervalles prédéterminés au moyen d'un certain nombre de fils de chaîne dirigés de façon longitudinale (7), de manière à prévenir un décalage longitudinal, la bande de renforcement (3) étant placée sur les surfaces supérieure et inférieure d'un noyau (2) composé de canevas ou analogue et étant entouré de caoutchouc (5), formant ainsi une courroie (1), la raideur transversale et le maintien de la forme de la courroie pouvant être améliorés par la disposition des cordes dures dans une direction orthogonale par rapport à la direction longitudinale de la courroie. De plus, les cordes dures ne peuvent pas se décaler, de façon longitudinale, de la courroie. L'invention concerne également un transporteur à courroie, notamment un transporteur à courroie tubulaire utilisant ladite bande.
Patent CA-2418792-C (CA)
Inventor: HILLIER CLYDE DONALD
IPC: B63B21/08
Filed: 2003-02-13
Granted: 2010-01-12
Abstract: A device for securing a rope or cable that may be easily mounted to an object or supporting structure. The device includes a base having a socket for receiving a plunger. A coil spring is located at the bottom of the socket and exerts an upward bias against the bottom of the plunger. Both the upper portion of the base and the plunger have circular apertures that may be selectively vertically aligned by depressing the plunger to permit horizontal passage of a rope through the aligned apertures. By releasing the plunger, a shearing force is applied to the rope due to the misalignment of the apertures, thereby frictionally securing the rope or cable within the device. A foot operated mechanism may be employed to assist the user in depressing the plunger. The plunger may also be selectively and/or releasably locked in a depressed position to maintain alignment of the apertures, facilitating insertion of the rope without the need for maintaining a downward force on the plunger.
Patent CA-2427389-C (CA)
Title: Method for the stabilization of a fluidized bed in a roasting furnace
Inventor: TASKINEN PEKKA
IPC: C22B1/10
Filed: 2001-11-13
Granted: 2010-08-17
Abstract: This invention relates to a method for stabilizing a fluidized bed used in roasting by adjusting the oxygen content of the roasting gas in the bed. The fine-grained material for roasting is fed into the furnace above the fluidized bed and the roasting gas, which causes the fluidizing, is fed into the bottom of the furnace through a grate. In this method, the total amount of oxygen in the roasting gas to be fed and the average total oxygen requirement of the material to be roasted are calculated and the ratio between them regulated so that the oxygen coefficient in the bed is over 1.
Patent CA-2431746-C (CA)
Title: Cold flow improvers for fuel oils of vegetable or animal origin
Inventor: KRULL MATTHIAS
IPC: C10L1/22
Filed: 2003-06-11
Granted: 2011-11-01
Abstract: Cold flow improvers for fuel oils of vegetable or animal origin.     The present invention provides an additive for improving the cold flow properties of vegetable or animal fuel oil, the additive comprising A) a copolymer of ethylene and 8-21 mol% of at least one acrylic or vinyl ester having a C1-C18-alkyl radical and B) a comb polymer of at least one C8-C16-alkyl ester of an ethylenically unsaturated dicarboxylic acid and at least one C10-C20-olefin, wherein the sum Q     (see above formula) of the molar averages of the carbon chain distributions in the alkyl side chains of the olefins (monomer 1) and the fatty alcohols (monomer 2) is from 23 to 27, w1 and w2 are the molar proportions of the individual chain lengths in the different monomers 1 and 2, and n1 and n2 are the side chain carbon atom lengths, excluding the originally olefinically bonded carbon atoms, of monomer 1, and the running variables i and j are the individual side chain lengths in the particular monomer groups.
Patent CA-2433318-C (CA)
Inventor: SAULAS ALAIN
IPC: B65D5/54
Filed: 2001-10-12
Granted: 2008-06-10
Abstract: A carton and blank for forming a carton for accommodating one or more articl es which carton is provided with an access structure (54, 238) for the removal of articles from within the carton. The access structure comprises a closure panel (56, 156, 224, 424) hinged to a carton wall (14, 114, 212, 412) for forward and backward pivotal movement and a movable platform hinged to the closure panel for moving the contents of the carton forward for their remova l in response to the forward pivotal movement of the closure panel. The invention is also directed to a divisible carton and blank for forming a divisible carton comprising two modular boxes (B, B1) for packaging articles , such as tablets (A) for example. Each modular box having a structure to acce ss the box interior and a common outer upper cover (260, 360, 460) arranged so as to secure the boxes together. A tear strip (266; 371, 375; 466) is provided so as to permit the boxes to be separated.
Patent CA-2435074-C (CA)
Title: Tete de coupe pour machine outil
Inventor: BJOERVIK PER
IPC: B23B29/03
Filed: 2002-01-15
Granted: 2009-03-17
Abstract: L'invention concerne une tête de coupe (13) conçue pour être fixée dans un adaptateur (9) dans une machine outil permettant l'enlèvement de copeaux. La tête de couple (13) comprend une collerette dont un premier côté forme une surface de raccordement (4) qui peut être fixée à l'adaptateur (9). En face de la collerette, un autre côté est ménagé qui forme au moins une surface (1A) présentant une saillie (8) s'étendant vers l'extérieur, des moyens de fixation étant ajoutés pour fixer un ajout de découpe (5) doté d'au moins un bord tranchant. Le poids de la tête de coupe (13) est réduit par rapport à la résistance de celle-ci, et la fréquence propre de la tête de coupe (13) est ainsi augmentée lorsqu'elle est fixée à l'adaptateur (9).
Patent CA-2441390-C (CA)
Inventor: MCDONALD DAVID THOMAS
IPC: G06Q10/10
Filed: 2002-03-19
Granted: 2007-10-23
Abstract: A system (10) and method (100) for efficiently processing messages (70) stored in multiple message stores (41) is described. Metadata (35) identifying a range of topically identical messages (47) extracted from a plurality of message stores (41) storing a multiplicity of messages (70) to be processed is iteratively copied. The metadata (35) for the extracted range of topically identical messages (47) is categorized. Those messages (70) containing substantially duplicative content within the extracted range are identified as duplicate messages (47). Those non-duplicate messages (44) within the extracted range are tallied into an ordering of conversation thread length (46). Those messages (70) whose content is recursively-included content (72, 73) within another of the tallied non-duplicate messages (44) are classified as near-duplicate messages (45). The remaining messages (71) are designated as unique messages (44) containing substantially non-duplicative content (71).
Patent CA-2448387-C (CA)
Inventor: LEE MIKE S
IPC: B05B5/03
Filed: 2002-05-24
Granted: 2008-02-05
Abstract: A capillary nozzle (1) is provided with mobile phase by mobile phase pump (2), which pumps the mobile phase through the capillary to discharge from the nozzle at opening (11). Electrical voltage is applied to capillary nozzle (1) by high power supply (3) through electrode (4).   A counter electrode (5), which is incorporated into the inlet of a mass spectrometer is "grounded", i.e., is at ground potential. The light source (7) illuminates electrospray (6) with intense light, which is positioned and focused by lens (71), and the light passing through the electrospray is detected by a photodetector, which generates an electronic signal which is interpreted by a computer, which then adjusts the distance between the electrospray nozzle and the counterelectrode of adjusts the voltage applied, to optimize the electrospray.
Patent CA-2450329-C (CA)
Title: Compositions for drilling fluids useful to provide flat temperature rheology to such fluids over a wide temperature range and drilling fluids containing such compositions
Inventor: THOMPSON JEFFREY
IPC: C08G69/48
Filed: 2003-11-20
Granted: 2012-05-29
Abstract: The invention is of oil-based drilling fluids including invert emulsion fluids that are able to maintain a relatively consistent rheological profile over a wide temperature range. The invention also includes new additives that enable the preparation of drilling fluids with viscosities that are less affected by temperature over a temperature range from less than about 40°F to more than about 250°F compared to conventional fluids. These additives are based on reaction products of polyamines and carboxylic acids with two or more carboxylic moieties combined with alkoxylated amines and fatty acid amides. In addition, this invention permits the use of reduced amounts of organoclay rheological additives in drilling fluids.