baber/WOPTO huggingface dataset:
Patent DE-68911157-D1 (DE)
Inventor: LONGO ANTONIO
IPC: C07J75/00
Filed: 1989-01-25
Granted: 1994-01-20
Abstract: The invention relates to a new process for the preparation of known aromatase inhibitors of the following formula (I) <CHEM>  wherein  each of R1 and R3, independently, is hydrogen or C1-C6 alkyl;  R2 is hydrogen, halogen or C1-C6 alkyl; and  R4 is hydrogen or fluorine; the process comprising submitting to Mannich reaction a compound of formula (II) <CHEM>  wherein R1, R2, R3 and R4 are as defined above and R is a lower alkyl group, and then dehydrogenating the respective 6-methylene-3-oxo- DELTA <4>-steroid derivative thus obtained.
Patent DE-68911461-D1 (DE)
Inventor: BERGONZONI LAURA
IPC: C12N15/70
Filed: 1989-09-15
Granted: 1994-01-27
Abstract: The present invention relates to the production, by recombinant DNA techniques, of derivatives of basic fibroblast growth factor (bFGF). These derivatives of bFGF can act as antagonists and/or superagonists of the wild type molecule in the angiogenic process. These derivatives, as well as wild type bFGF, may be prepared by the use of strains or E. coli which have been transformed with plasmids carrying nucleotide sequence coding for human and bovine bFGF and their derivatives.
Patent DE-68911679-D1 (DE)
Inventor: PILATI ROMANO
IPC: H02K1/27
Filed: 1989-12-05
Granted: 1994-02-03
Abstract: The magnets (11) on the surface of brushless motor rotors (10) are divided into groups. Each group is clad by a sheet (12), the edges of which are turned and inserted in radial slots (15) of the rotor , where they are fixed by bolts (16) or by longitudinal tenons inserted in the slots (15).
Patent DE-68926547-D1 (DE)
Inventor: ESKELINEN JUHANI
IPC: D21G1/02
Filed: 1989-03-13
Granted: 1996-07-04
Abstract: The invention concerns a roll or cylinder for a paper machine or for a paper finishing machine, in particular a calender roll, which can be heated. The roll (1) comprises a cylindrical mantle (1 min ) and a stationary axle (2) fitted inside said mantle (1 min ), on which said axle (2) nozzles (10) are installed, which spray liquid in the axial direction of the roll (1) so as to produce a uniform temperature profile of adjustable level. Both ends of the axle (2) are provided with a feed opening (8), a duct (19) and a nozzle (9) for cold liquid for the cooling of the roll (1) ends.
Patent DE-68928958-D1 (DE)
Inventor: DANILATOS GERASIMOS
IPC: H01J37/244
Filed: 1989-10-13
Granted: 1999-04-29
Abstract: An improved gaseous detector device for an environmental scanning electron microscope (ESEM) is provided. The detector device includes a generally annular electrode assembly having an inner electron detector formed of a thin ring, an intermediate electron detector positioned radially outwardly of the inner electron detector which is formed of a first plurality of concentric arc segments, and an outer electron detector positioned radially outwardly of the intermediate electron detector which is formed of a second plurality of concentric arc segments. The first plurality of concentric arc segments is positioned generally normal to the second plurality of concentric arc segments to obtain a directional topographic contrast. The inner, intermediate and outer electron detectors are aligned along generally the same horizontal plane.
Patent DE-69000524-D1 (DE)
Inventor: TROIANIELLO LUCIANO
IPC: E04F13/08
Filed: 1990-06-21
Granted: 1993-01-14
Abstract: At least one edge (14) of each of said panels (15) is provided with at least one recess or cavity (13) suitable for housing, in operation, a first arm (12) belonging to a mechanical retaining element (11) of the external surface of said panels (15), said mechanical retaining element (11) cooperating with a fixed supporting structure internal to the building, wherein said mechanical retaining element (11) is provided with another arm (18) having an extension (19) insertable with a predetermined clearance into a slot (20) provided in a section (21) integral with said fixed supporting structure, said extension (19) being movable inside of said slot (20) about a predetermined distance and according to three, mutually perpendicular, directions, two of said directions being contained in a plane which is parallel to the major surface of said panel (15), the third direction being contained in a plane which is perpendicular to said major surface of said panel (15).
Patent DE-69009489-D1 (DE)
Inventor: MITCHELL JULIAN
IPC: C08K3/06
Filed: 1990-08-09
Granted: 1994-07-07
Abstract: Tires having a sidewall composed of a composition formed by curing a blend comprised of (A) high molecular weight (6x105  &upbar& Mu) ethylene/alphaolefin/nonconjugated polyene terpolymer; (B) a highly unsaturated rubber; and (C) a curative system comprised of sulfur and/or a sulfur-donor compound, an organic(hydro)peroxide curative and a sulfur cure accelerator exhibit desirable reduced internal heat buildup and improved adhesion to adjacent rubber carcass and tread portions of the tire.
Patent DE-69010490-D1 (DE)
Inventor: NEVEU JEAN-LOUP
IPC: D04H13/00
Filed: 1990-11-28
Granted: 1994-08-11
Abstract: PCT No. PCT/FR90/00861 Sec. 371 Date Jul. 26, 1991 Sec. 102(e) Date Jul. 26, 1991 PCT Filed Nov. 28, 1990 PCT Pub. No. WO91/08333 PCT Pub. Date Jun. 13, 1991.The invention concerns a method for making a non-woven from unbleached cotton or other natural ligno-cellulose fibers comprising a surface layer of substances rendering the fiber hydrophobic and comprising the following stages: formation of a sheet of unbound fibers on a water-permeable cloth, tangling the sheet fibers by means of a plurality of water jets issuing from arrays of injectors located transversely to the direction of advance of the support, the method being characterized in that the total energy imparted to the sheet by the set of jets is at least equal to a minimum threshold corresponding to the value at which said sheet becomes hydrophilic. The invention also concerns a hydrophilic non-woven made by hydraulic binding from unbleached cotton or other natural, ligno-cellulose fibers such as flax, hemp or ramie and free of chemical treatment.
Patent DE-69024114-D1 (DE)
Inventor: PERRONE ETTORE
IPC: C07D499/897
Filed: 1990-07-03
Granted: 1996-01-25
Abstract: There is provided a process for the preparation of compounds of formula (I) useful as antibacterials: <CHEM> wherein R represents hydrogen atom or a hydroxy protecting group, which process comprises reacting a compound of formula (II) <CHEM> wherein R is as defined above, with an oxalyl halide in an inert solvent; optionally converting the resultant compound of the formula III <CHEM> wherein R is as defined above and X is a halogen atom into a compound of the formula III in which X represents a hydroxy group by hydrolysis; either (i) treating the compound of formula III in which X is a halogen atom with a compound of the formula IV <CHEM> wherein Y is a hydroxy group in the presence of an acid scavenger or an organic or inorganic base or (ii) treating the compound of the formula III in which X is a hydroxy group, with a compound of the formula IV in which Y is a leaving group in the presence of a base; cyclizing the resultant compound of the formula V <CHEM> wherein R is as defined above and optionally deprotecting the resultant compound of the formula I wherein R is a hydroxy protecting group to obtain a compound of the formula I wherein R is a hydrogen atom.
Patent DE-69026639-D1 (DE)
Inventor: CRAWLEY GRAHAM CHARLES
IPC: C07D413/14
Filed: 1990-02-23
Granted: 1996-05-30
Abstract: The invention concerns a heterocyclic cyclic ether of the formula I   <CHEM> wherein Q is an optionally substituted 6-membered monocyclic or 10-membered bicyclic heterocyclic moiety containing one or two nitrogen atoms; A is (1-6C)alkylene, (3-6C)alkenylene, (3-6C)alkynylene or cyclo(3-6C)alkylene;  X is oxy, thio, sulphinyl, sulphonyl or imino; Ar is phenylene which may optionally bear one or two substituents or Ar is an optionally substituted 6-membered heterocyclene moiety containing up to three nitrogen atoms; R<1> and R<2> together form a group of the formula -A<2>-X<2>-A<3>- which, together with the oxygen atom to which A<2> is attached and with the carbon atom to which A<3> is attached, defines a ring having 5 to 7 ring atoms, wherein A<2> and A<3> each is (1-3C)alkylene and X<2> is oxy, thio, sulphinyl, sulphonyl or imino, and which ring may bear one, two or three substituents; and R<3> is hydrogen, (1-6C)alkyl, (2-6C)alkenyl, (2-6C)alkynyl or substituted (1-4C)alkyl;  or a pharmaceutically-acceptable salt thereof. The compounds of the invention are inhibitors of the enzyme 5-lipoxygenase.
Patent DE-69027042-D1 (DE)
Inventor: HEINO JUKKA
IPC: D21F1/60
Filed: 1990-06-26
Granted: 1996-06-20
Abstract: A method and an apparatus for treating pulp are described. The apparatus comprises a vessel (10) in which a wire-surfaced cylinder (12) is mounted and tightly sealed at the ends, a doctor blade (92) located externally of the wire surface and a source of pressure medium for moving and discharging a pulp web from the wire surface. A plurality of adjacent filtrate compartments (20) form a shell on the cylinder (12) and filtrate tubes are located at at least one end of the cylinder (12) and extend inwardly from the compartments (20). A suction means is connected to the inner end of the filtrate tubes and the doctor blade (92) is provided such as to be flexible in the radial direction of the cylinder (12) to provide an improved removal of pulp from the wire surface. <IMAGE>
Patent DE-69027090-D1 (DE)
Inventor: MORIMOTO KIYOSHI
IPC: B65G53/52
Filed: 1990-11-08
Granted: 1996-06-27
Abstract: A high density pneumatic transport system of solid materials from an airtight transport tank (3) through a transport pipe (4) into a collector (8). In the airtight transport tank (3) materials are successively fed into a charge tank (30) by reciprocating a slide damper (3A). Simultaneously materials stored in the charge tank (30) are successively pushed out into the transport pipe (4) by supplying pressurized gas intermittently and transported continusouly at high density through a lower horizontal pipe (41) and a vertical riser pipe (42), then transported in the form of a long column (P) in an upper horizontal pipe (43) at a very low speed by deceleration by a divergent means (43a), and finally collected into a storage tank (80) of collector (8).
Patent DE-69031830-D1 (DE)
Inventor: KADDURAH-DAOUK RIMA
IPC: A61K31/70
Filed: 1990-02-14
Granted: 1998-01-29
Abstract: A method of inhibiting growth rate, transformation or metastasis of mammalian cells, particularly epithelial cells, in which activity of at least one enzyme which participates in purine metabolism and regulations of nucleotide levels is elevated. In particular, a method of inhibiting transformation of mammalian cells by a DNA tumor virus, a DNA tumor virus factor or other factor which has an equivalent effect on cells.
Patent DE-69100772-D1 (DE)
Inventor: CUSSAC MICHEL
IPC: G01N3/04
Filed: 1991-04-10
Granted: 1994-01-27
Abstract: Jaws (3) and (4) are used to grip the specimen (E) along its breadth and to create the shear by a mutual displacement of the specimen also along its breadth. The jaws are fitted with clamping blocks (36) which can move in the direction of the thickness of the specimen in order to prevent it from buckling. Application to the study of strength of materials, particularly composite materials. <IMAGE>
Patent DE-69103585-D1 (DE)
Inventor: WATTS RONALD ARTHUR
IPC: G07D1/00
Filed: 1991-01-11
Granted: 1994-09-29
Abstract: A coin dispenser (1) pushes coins (3) out one by one from the foot of stack confined in a tube (2). The coins are then confined to a guide track (5, 11, 19, 20), each coin being pushed by the next one upstream. The track may lead upwards. At the delivery end the coins (3) topple into a chute (10) and thence into a collecting chamber (14) where they are visible through a window (15). When all the allotted coins have amassed, a mechanism (16, 17) operates to drop them into a collection pocket (18). The track may be straight, it may have an upward curve, and/or it may twist or bend to one side.
Patent DE-69104570-D1 (DE)
Inventor: MERRITT DAN
IPC: F02B19/18
Filed: 1991-07-12
Granted: 1994-11-17
Abstract: An internal combustion engine has first and second cylinders (12, 14), the first cylinder (12) having a larger swept volume than the second cylinder (14) and the second cylinder being formed in the crown of the first cylinder. First and second pistons (16, 18) are reciprocable respectively in the first and second cylinders (12, 14), the second piston (18) being formed as a protrusion on the crown of the first piston (16). The first cylinder has an air inlet (25) and an exhaust outlet (27) whilst a first fuel source (34) provides fuel to the second cylinder (14). The second piston has a crown (35) which is spaced from and connected to the crown (36) of the first piston and which has an edge (37) which is relatively thin in the axial direction compared to the spacing of the first piston crown from the second piston crown. This defines a combustion space (20) between the piston crowns and a side wall (14a) of the second cylinder (14) when the pistons are substantially at the inner dead centre position. The combustion space (20) communicates with both cylinders (12,14) during part of the expansion stroke. Inhibiting means is also provided for inhibiting ingression prior to the pistons (16,18) arriving at or adjacent the inner dead centre position. This can take the form of a gap (128) between the second piston crown (35) and the second cylinder side wall (14a) with a peripheral groove (39) in the second cylinder wall at its upper end to enable the fuel/air mixture in the second cylinder (14) above the crown (35) to bypass the piston crown when the latter is at its inner dead centre position and enter the combustion space (20).
Patent DE-69113198-D1 (DE)
Inventor: HO BOSCO P
IPC: C02F1/52
Filed: 1991-10-02
Granted: 1995-10-26
Abstract: An on-line monitoring/control method and system which utilizes a tube clarifier to monitor and, optionally, control a clarification process.
Patent DE-69125521-D1 (DE)
Inventor: ERIKSSON LARRY J
IPC: G10K11/178
Filed: 1991-05-01
Granted: 1997-05-15
Abstract: An active acoustic attenuation system (200) has a first adaptive filter model M modeling the acoustic path P from an input transducer (10) to an output transducer (14), and a second adaptive filter model Q modeling the overall system from the input transducer (10) to an error transducer (16). A third adaptive filter model T models the transfer function S of the output transducer (14) and the error path E between the output transducer (14) and the error transducer (16), without an auxiliary random noise source.
Patent DE-69126145-D1 (DE)
Inventor: STEWART RAY
IPC: C05G3/00
Filed: 1991-12-06
Granted: 1997-06-19
Abstract: Food may be packaged and preserved for extended periods using intelligent polymers formed into food containers which have specific and variable gas permeabilities. The polymers used in forming the food packages are intelligent in that they have permeabilities which may be radically and reversibly changed by relatively small changes in temperature. By using different types and formulations of polymers and various temperatures, it is possible to create an environment within the food package which adjusts to the respiration of the food so as to best preserve the color, quality and/or shelf life of the food. The polymers are side-chain crystallisable polymers designed and formulated so as to provide a material which is substantially impermeable to a gas such as oxygen, carbon dioxide or water vapor at a temperature below a give phase transition point and permeable to the same gas at a temperature above that point.
Patent DE-69127944-D1 (DE)
Inventor: JONES BRIAN EDWARD
IPC: C12N9/28
Filed: 1991-08-06
Granted: 1997-11-20
Abstract: Gram-negative bacteria, which are obligate alkaliphiles, have been isolated from samples of soil, water and sediment and a number of other sources obtained from in and around soda lakes. These bacteria have been analyzed according to the principles of numerical taxonomy with respect to each other, as well as to a variety of known bacteria. In addition, these bacteria are further circumscribed by an analysis of various chemotaxonomic characteristics. The bacteria produce various alkali-tolerant enzymes which may be used in various industrial processes requiring such enzymatic activity in a high pH environment.
Patent DE-69201222-D1 (DE)
Inventor: CLARAC ANDRE
IPC: C08L95/00
Filed: 1992-05-21
Granted: 1995-03-02
Abstract: The invention relates to a method for producing cold dense-graded bituminous mixes consisting of coarse elements (GG) and fine elements (GF), which is characterised by a double coating according to which there are added, in succession, into a mixer (2") : the coarse elements (GG), a first emulsion (EBPF), the fine elements (GF) and a second emulsion (EBP), and everything is mixed for a sufficient length of time to obtain a homogeneous mixture (7') which can be stored for the necessary period. <IMAGE>
Patent DE-69201865-D1 (DE)
Inventor: HUGHES IAN
IPC: B29C39/42
Filed: 1992-01-30
Granted: 1995-05-04
Abstract: A process for manufacturing a padded element using a mold having a mold cavity and including an upper mold having an interior surface complimentary to the upper surface of the padded element and a lower mold having an interior surface complimentary to the lower surface of the padded element. The process includes placing a trim cover on the upper mold, with the trim cover comprising an inner surface and a finished outer surface in contact with substantially the entire interior surface of the upper mold, placing a liquid foamable polymeric composition on the interior surface of the lower mold and closing the upper mold and the lower mold after the liquid foamable polymeric composition expands to fill from about 50 to about 90 volume % of the mold cavity and prior to expansion of the liquid foamable polymeric composition to a point corresponding to the interior surface of the upper mold in a closed position. The liquid foamable polymeric composition expands in a direction substantially away from the lower mold and adheres to the inner surface of the trim cover. A substantial amount of expansion gases produced during expansion of the liquid foamable polymeric composition are vented prior to closing of the upper mold and the lower mold.
Patent DE-69202120-D1 (DE)
Inventor: VIDALUC JEAN-LOUIS
IPC: C07C275/14
Filed: 1992-07-23
Granted: 1995-05-24
Abstract: New urea derivatives corresponding to the general formula 1  (* CHEMICAL STRUCTURE *) 1 in which: R1 represents a C1-C4 alkyl group; R2 represents: a C5-C7 cycloalkyl group a cycloalkylmethyl group in which the cycloalkyl radical contains from 5 to 7 carbon atoms a benzyl group a benzyl group in which the aromatic ring bears a C1-C4 alkyl group, a C1-C4 alkoxy group, a halogen atom or a nitro group; A represents an oxygen atom or a methylene radical; n represents 1 or 2; X represents an oxygen or sulfur atom; B represents a direct bond, a methylene radical or a carbonyl radical; as well as the therapeutically acceptable salts of these molecules. The invention also relates to the application of the compounds of general formula 1 in therapy, and to the preparation processes.
Patent DE-69208078-D1 (DE)
Inventor: MAHIEU CLAUDE
IPC: A61Q1/02
Filed: 1992-12-03
Granted: 1996-03-14
Abstract: Fluorinated hydrocarbon compounds have formula (I): RF?-(CH2?)n?-X-[C3?H5?(OH)]-(Y)x?-RH?, in which C3?H5?(OH) represents structures (Ia) or (Ib): RF? is a perfluorinated C4?-C20? alkyl radical or a mixture of perfluorinated C4?-C20? radicals; RH? is a straight or branched C1?-C22? alkyl radical or a mixture of straight or branched C1?-C22? alkyl radicals or an aryl or aralkyl radical; n is from 0 to 4; X stands for O, S, (a) or (b); x stands for 0 or 1; Y stands for O, S, (a) or (b); with the proviso that when X = S, (a) or (b), Y is not S, (a) or (b). The use of said compounds as amphiphilic compounds, the method of preparing them, and the cosmetic compostions containing them are also disclosed.
Patent DE-69212131-D1 (DE)
Inventor: HALL TODD
IPC: A61L29/00
Filed: 1992-12-23
Granted: 1996-08-14
Abstract: A small diameter wire guide (10) for medical procedures. The wire guide includes a mandrel (11) of metallic superelastic material, such as nitinol, having a diameter less than 0.020 inches and which completes its transformation to austenite at a temperature of about 14 DEG C. The mandrel has a constant diameter over a majority of its length and includes a number of tapered portions (14,16); and reduced-diameter portions (15,17) in its distal region (13). A flexible radiopaque platinum coil (18) is attached at the distal region of the mandrel and coaxially surrounds a portion of the distal region. A smoothly rounded tip (21) is attached to the distal tip of the mandrel and coil and serves to shield the distal end of the coil during the insertion procedure into the patient. <IMAGE>
Patent DE-69212384-D1 (DE)
Inventor: CIAURRIZ JUAN IGNACIO
IPC: A47J31/40
Filed: 1992-05-12
Granted: 1996-08-29
Abstract: The improvements are applicable to those vending-machines dispensing coffee infusions where a quantity of coffee is duly batched and compacted, passing hot water over the same thereby to obtain the infusion which shall exit and be collected in a suitable package. The improvements lie in the actual batcher and in the mechanism for obtaining the infusion. The batcher includes a cylindrical body (1) with a rotatory vane (3) within the same, in which two cavities (5) are formed which are alternately filled with batched coffee (6) to be hauled in such rotation to a drop duct (13), reaching a receptacle (11) whose bottom is made up by a lower seat (12), the latter and the receptacle body (11) mounted on a main shaft (15) which can travel up and down and is in turn provided with turning movement to allow the batched coffee (6) to be carried from the drop duct (13) to face a compacting piston (24) provided in a fixed body (18), which shaft (15) is driven by a piston. <IMAGE>
Patent DE-69219226-D1 (DE)
Inventor: HANCOCK JOHN EDWIN
IPC: E06B3/08
Filed: 1992-07-09
Granted: 1997-05-28
Abstract: A structure and method of making same is described, which comprises at least four elongate members (10), joined to form a rectangular framework for supporting panelling (90), the join between pairs of elongate members (10) is provided by locating in an axially extending bore (22) of one of them an expansion element (100) which is engaged by a bolt (102) passing through an aperture formed to extend transversely of the axis of the other of said pair. Each elongate member (10) may have two axially extending parallel bores (22, 22 min ) formed therein with pairs of expansion elements (100, 100 min ) and bolts (102, 102 min ) used with them. The elongate members (10) are formed with walls (26, 36) defining cavities (30, 34) extending parallel to the or each bore (22) therein. The walls (26, 36) are adapted to engage legs (46, 48, 56) of elongate cover elements (42, 52) to be fitted to said members (10). The walls and cover elements may be used to define sets of slots running parallel to said cavities (22) of the elongate members, in which slots edges of panelling (90) are received. The panelling may comprise a rectangular cut piece of solid material with lugs at each edge received in said slots, or be two laminar layers (90) (possibly glass) the edges of which are fitted said slots. The volume between layers (90) may be void or filled with insulating material. Resilient inserts may be placed in the slots to hold edges of panelling received therein. The slots may be used to support brushes or other sealing elements. One form of cover element (150) described for use on a door structure has a part (162) extending past the elongate member (10) on which it is supported and itself supports a resilient sealing strip (170) engagable with a surface of a cover element (54) of an elongate member (10 min ) adjacent the door when the door is closed. <IMAGE>