baber/WOPTO huggingface dataset:
Patent IL-133613-A (IL)
Title: Epothilone derivatives and pharmaceutical compositions containing same
IPC: C07D493/04
Filed: 1998-06-16
Abstract: The present invention relates to compounds of the formula <CHEM>  Q is selected from the group consisting of <CHEM> G is selected from the group consisting of alkyl, substituted alkyl, substituted or unsubstituted aryl, heterocyclo, <CHEM> W is O or NR15; X is O or H,H; Y is selected from the group consisting of O; H,OR16; OR17,OR17; NOR18; H,NOR19; H,NR20R21; H,H; or CHR22; OR17 OR17 can be a cyclic ketal; Z1, and Z2 are selected from the group consisting of CH2, O, NR23, S, or SO2, wherein only one of Z and Z2 is a heteroatom; B1 and B2 are selected from the group consisting of OR24, or OCOR25, or O2CNR26R27; when B1 is H and Y is OH, H they can form a six-membered ring ketal or acetal; D is selected from the group consisting of NR28R29, NR30COR31 or saturated heterocycle R1, R2, R3, R4, R5, R6, R7, R13, R14, R18, R19, R20, R21, R22, R26, and R27 are selected from the group H, alkyl, substituted alkyl, or aryl and when R1 and R2 are alkyl can be joined to form a cycloalkyl; R3 and R4 are alkyl can be joined to form a cycloalkyl; R9, R10, R16, R17, R24, R25, and R31 are selected from the group H, alkyl, or substituted alkyl; R8, R11, R12, R28, R30, R32, R33, and R30 are selected from the group consisting of H, alkyl, substituted alkyl, aryl, substituted aryl, cycloalkyl, or heterocyclo; R15, R23 and R29 are selected from the group consisting of H, alkyl, substituted alkyl, aryl, substituted aryl, cycloalkyl, heterocyclo, R32C=O, R33SO2, hydroxy, O-alkyl or O-substituted alkyl, the pharmaceutically acceptable salts thereof and any hydrates, solvates or geometric, optical and stereoisomers thereof, with the proviso that compounds wherein W and X are both O; and R1, R2, R7, are H; and R3, R4, R6, are methyl; and R8, is H or methyl; and Z1, and Z2, are CH2; and G is 1-methyl-2-(substituted-4-thiazolyl)ethenyl; and Q is as defined above  are excluded.
Patent IL-136733-A (IL)
Title: Pharmaceutical composition containing sibutramine and orlistat
IPC: A61K31/365
Filed: 1998-12-16
Abstract: A method for the treatment of obesity in a human in need of such treatment which comprises administration to the human of a therapeutically effective amount of a compound of formula Iincluding enantiomers and pharmaceutically acceptable salts thereof, in which R1 and R2 are independently H or methyl, and a therapeutically effective amount of a compound of formula IIwherein the compound of formula I and the compound of formula II are administered simultaneously, separately or sequentially.
Patent IL-140453-A (IL)
Title: Method and apparatus for producing orthohydrogen and/or parahydrogen
IPC: C25B9/17
Filed: 1999-06-21
Abstract: An apparatus for producing orthohydrogen and/or parahydrogen. The apparatus includes a container holding water and at least one pair of closely-spaced electrodes arranged within the container and submerged in the water. A first power supply provides a particular first pulsed signal to the electrodes. A coil may also be arranged within the container and submerged in the water if the production of parahydrogen is also required. A second power supply provides a second pulsed signal to the coil through a switch to apply energy to the water. When the second power supply is disconnected from the coil by the switch and only the electrodes receive a pulsed signal, then orthohydrogen can be produced. When the second power supply is connected to the coil and both the electrodes and coil receive pulsed signals, then the first and second pulsed signals can be controlled to produce parahydrogen. The container is self-pressurized and the water within the container requires no chemical catalyst to efficiently produce the orthohydrogen and/or parahydrogen. Heat is not generated, and bubbles do not form on the electrodes.
Patent IL-146222-A (IL)
Title: Use of compositions comprising benzodiazepines for the manufacture of medicaments for the treatment of conditions associated with dysregulation of cell death and pharmaceutical compositions thereof
IPC: A61P37/00
Filed: 2001-10-29
Abstract: Benzodiazepine compounds, and methods for using those compounds are provided. Some of the benzodiazepine compounds include 1,4-benzodiazepine-2-one and 1.4-benzodiazepine-2,5-dione compounds of structures (I) or (II): wherein R 1 , R 2 , R 3  and R 4  are as defined. The invention also includes enantiomers, pharmaceutically acceptable salts, prodrugs or derivatives of the benzodiazepine compounds. Any one or more of these benzodiazepine compounds can be used to treat a variety of dysregulatory disorders related to cellular death. Such disorders include autoimmune disorders, inflammatory conditions, hyperproliferative conditions, viral infections, and atherosclerosis. In addition, the above compounds can be used to prepare medicaments to treat the above-described dysregulatory disorders. The benzodiazepines can also be used in drugs screening assays and other diagnostic methods.
Patent IL-156858-A (IL)
Title: Assigning clusters of demodulation elements in a spread spectrum system
IPC: H04B1/7117
Filed: 2003-07-09
Abstract: An apparatus, such as a subscriber unit or a base station within a spread spectrum communication system, may add one or more additional "virtual" paths to a list of candidate paths when assigning demodulation elements. These "virtual" paths are added as candidate paths even though a corresponding peak was not necessarily detected within a received spread spectrum system. The list of paths may include a first path having a time offset approximately equal to a time offset for one of the demodulation elements, and the virtual path having a short time separation from the first path. The time separation between the paths may be, for example, less than 2 chips.
Patent IL-159894-A (IL)
Title: Chimeric polypeptide comprising apoptosis factor, method of inducing the same in a cell in vitro, pharmaceutical composition comprising the same and use thereof in the manufacture of hyperproliferative disorder targeting medicament
Inventor: ROSENBLUM MICHAEL G
IPC: C12N5/06
Filed: 2004-01-15
Abstract: The present invention relates to targeted killing of a cell utilizing a chimeric polypeptide comprising a cell-specific targeting moiety and a signal transduction pathway factor. In a preferred embodiment, the signal transduction pathway factor is an apoptosis-inducing factor, such as granzyme B, granzyme A, or Bax.
Patent IL-163068-A (IL)
Title: Method and relevant device for revealing objects
IPC: G01J1/42
Filed: 2004-07-15
Abstract: The invention concerns a method, and relevant device, for remote sensing objects, characterised in that said objects are in a condition of thermal emission that is variable during time, and in that it comprises the following phases: A. acquisition of a map of the radiation coming from the surface of the portion of space within or behind which the object to be sensed is supposed to be, at least at a first time t<SUB>1 </SUB>and a second time t<SUB>2</SUB>, such times being successive to each other; B. acquisition of a map of the radiation coming from the surface of said portion of space, considered at a third instant t* different from said at least two times t<SUB>1 </SUB>and t<SUB>2</SUB>; C. summation of the maps of said at least two times t<SUB>1 </SUB>and t<SUB>2 </SUB>as obtained from the phase A; D. subtraction of the map at said time t* as resulting from the phase B, from the sum as resulting from the phase C; E. comparison between the values of each portion of map area as resulting from the phase D and a threshold value of the radiation intensity for the material of the sought objects; F. identification of the material of the object under investigation with the sought material, when the result of the comparison of the phase E has provided the presence of at least a certain number n of area portions of said space portion, with n>=1, whose value for said radiation is larger than said threshold value.
Patent IL-183124-A (IL)
Title: 9- substituted tetracycline compound and use of a 9- substituted tetracycline compound in the preparation of a medicament
IPC: C07C237/26
Filed: 2007-05-10
Abstract: The present invention relates to novel chemistries which allow for heretofore unobtainable substituted tetracycline compounds which exhibit significant antibacterial activity. The methods disclosed herein utilize reactive tetracycline-based precursor compounds, reactive organic substituent precursors and transition metal catalysts under conditions such that a tetracycline compound substituted with the desired organic substituent is formed. In one embodiment of the invention, a substituted tetracycline compound may be prepared by combining a reactive tetracycline-based precursor compound such as an arene tetracycline diazonium salt, and a reactive organic substituent precursor, e.g., alkenes, substituted alkenes, vinyl monomers, aromatics and heteroaromatics, in the presence of a transition metal catalyst, such as palladium chloride, under conditions such that a tetracycline compound substituted with the organic substituent is formed. Such compounds may optionally act as intermediates for making other compounds, e.g., hydrogenation of unsaturated groups on the substituent.
Patent IL-185275-A (IL)
Title: N-sulphonylpyrrole derivatives and pharmaceutical compositions containing the same
Filed: 2007-08-14
Abstract: Compounds of a certain formula (I), in which R1, R2, R3, R4, R5, R6 and R7 have the meanings indicated in the description, are novel effective HDAC inhibitors.
Patent IL-186237-A (IL)
Title: Flexible bicycle derailleur hanger
Inventor: SCHAFFER ALON
IPC: B62M9/125
Filed: 2007-09-24
Abstract: Derailleur mounts for use in bicycles. The derailleur mount comprises an elastic element having a functional state and a collapsed state. The elastic element is configured for reducing at least some of an impact force of at least 300 Newton (N) applied on the bicycle by switching from the functional state to the collapsed state. The elastic element is configured for reverting from the collapsed state to the functional state after the impact force is removed.
Patent IL-188460-A (IL)
Title: Diagnostic methods for influenza
IPC: A61K38/08
Filed: 2007-12-27
Abstract: The invention provides method and compositions for determining the presence and amount of an influenza virus in a sample including high risk strains of Influenza A. Also provided are methods for determining whether a subject is infected with a influenza virus, as well as, the type and strain of the influenza virus. The methods involve contacting a sample from the subject with a PDZ polypeptides (PDZ) and/or PDZ ligands (PL) and determining whether binding interactions occur between PDZ and PL. Assays for identifying anti-viral agents are also provided, as well as, methods for using the compositions to alter PDZ binding to PL in influenza infected cells.
Patent IL-191456-A (IL)
Title: Message handling in an ip multimedia subsystem
Filed: 2008-05-15
Abstract: A method of handling a Session Initiation Protocol (SIP) communication at a SIP application server within an IP Multimedia Subsystem, the method including handling a message received from a Serving Call/State Control Function node based upon a header of the message containing the URI of the served user. The SIP message is handled according to one of an originating case based upon a P-Asserted Identity contained in the SIP message or a terminating case using a Request-Uniform Resource Identifier (R-URI) of the SIP message, the appropriate case being identified in said header.
Patent IL-225808-A (IL)
Title: Sesquihydrate of 1-{(2s)-2-amino-4-[2,4-bis(trifluoromethyl)-5,8-di-hydropyrido[3,4-d]pyrimidin-7(6h)-yl]-4-oxobutyl}-5,5-difluoro-piperidin-2-one tartrate, process for its preparation and pharmaceutical compositions comprising it for treating diabetes and obesity
IPC: C07D/
Filed: 2013-04-17
Abstract: The present invention relates to 1.5 hydrate of of 1-{(2S)-2-amino-4-[2,4-bis(trifluoromethyl)-5,8-dihydropyrido[3,4-d]pyrimidin-7(6H)-yl]-4-oxobutyl}-5,5-difluoropiperidin-2-one tartrate, a process for preparing the same, and a pharmaceutical composition for inhibiting DPP-IV, which comprises said compound as the active component.
[WO2012060590A2]
Patent JP-S5224449-A (JP)
Title: Circular polarized antenna
Inventor: YAZAWA NORIHIKO
IPC: H01Q13/06
Filed: 1975-08-20
Abstract: PURPOSE:To provide a small simple-structured circular polarized radiator featuring excellent radiation characteristics that can be used for the primary radiator of a circular polarized papabolic antenna.
Patent JP-H08267312-A (JP)
Title: Hole angular part machining tool
Inventor: SHODA ISAO
IPC: B23D23/00
Filed: 1995-03-30
Abstract: PURPOSE: To make a hole angular part machinable into an acute point (pin angle) quickly without entailing any crack by installing two chisels, being opposed to each other as separating in the axial direction, in a columnar shank. CONSTITUTION: Respective cutting edges 4a and 5a of two chisels 4 and 5 are bent into a rectangular chevroned form on a surface orthogonal with a shaft center line of a shank 1, while they are opposed in a point symmetrical manner to a shaft center of this shank 1, thereby forming a square or rectangular four- corner part by means of two sides od each of the cutting edges 4a and 5a. An angular part machining tool A is positioned aright so as to make the two sides of these cutting edges 4a and 5a become parallel with a horizontal side 11a and a vertical side 11b of a rectangular hole 11 of a work (window frame) 10, and then it is attached to a chuck 9 of a working machine via an upper part of the shank 1.  In this state intact, the angular part machining tool A is traveled in both X and Y axial directions in the hole 11 of the work 10, through which each angular part 11c of the hole is machined.
Patent JP-S60243555-A (JP)
Title: Ion-selecting electrode and manufacture thereof
Inventor: YAMADA SADAO
IPC: G01N27/333
Filed: 1984-05-18
Abstract: PURPOSE:To improve electrical insulation characteristic of an ion-selecting electrode and reduce thickness of the said layer of an expensive material, by providing a dielectric layer on a supporting body having electrical insulation characteristic and forming 2 electrodes or more by forming a mechanically worked groove. CONSTITUTION:A dielectric layer 34, for instance, dielectric metal, dielectric oxidized metal, etc. is provided on an electric insulating supporting body 32. Next, a mechanically worked groove 38 is formed in the layer 34 with a cutting bite, etc. and the layer 34 is divided into electrically insulated sections 34a and 34b. Further, electrodes 40a, 40b are installed on the insulated sections 34a and 34b respectively. Next, an ion-selecting layer 36 is coated on the separated dielectric layer 34. Further, as the layer 36, a mixture of inert graphite, etc. and redox couple Fe(CN)6<3->/Fe(CN)6<4-> is employed. Consequently, as the dielectric layer is cut, the ion-selecting electrode is provided with better insulating characteristic and tighter contact with a mask for porous bridge installation covering the top surface is obtained.
Patent JP-S62256920-A (JP)
Title: Cooling method for controlling transformation rate of steel products
Inventor: YAHIRO KAZUHIRO
IPC: C21D9/573
Filed: 1986-04-30
Abstract: PURPOSE:To cool steel products at a prescribed transformation rate pattern by setting the targets of the transformation rate pattern and temp. pattern, calculating the corresponding temp. from the transformation rates of the steel products detected at plural points and the elapsed time and changing the spraying of cooling water. CONSTITUTION:A steel sheet 10 emitted from the final stand 12 is subjected to controlled cooling in a cooling water bank 16. The data on rolling conditions, steel products, etc., are inputted to a transformation rate set up device 22 during this time. The target transformation rate pattern and target temp. pattern are set from the elapsed time and transformation rates at the plural points. An arithmetic unit 28 determines the transformation rate from the values detected by the sensors 26 at the respective points and detects the elapsed time. A blank control device 24 compares the elapsed time detected at the above-mentioned present point of the time and the elapsed time calculated from the target pattern. Opening and closing of the cooling water bank 16 after the sensor 26 (after the present point of the time) are executed in accordance with the difference therebetween, by which the cooling of the steel sheet 10 is controlled. The uniform material quality is obtd. in the longitudinal direction of the steel products by the above-mentioned method.
Patent JP-H01313086-A (JP)
Title: Sewing machine equipped with needle rod supported by frame
Inventor: SHIYOTSUPUFU KAARUUDEIITERU
IPC: D05B55/14
Filed: 1989-04-21
Abstract: PURPOSE: To enable frame rocking at high speed with little noise and to enable the motion of a needle rod to be executed in a workpiece movement direction by freely driving a frame by means of relying on the motion of an arm shaft through the use of transmission means which are mutually linked in terms of a fixed shape. CONSTITUTION: The frame 22 is fixedly connected to a rocking shaft 43 which is supported by a sewing machine arm 4, a lever 44 is supported in its free end part and it is fixed to the rocking shaft 113 by a screw 115. The lever 44 is provided with a right side arm 45 and a left side arm 46. Rolls 47 and 49 are minutely adjusted as against the travelling orbits of cam boards 20 and 21 and reduce the traveling noise of the transmission means 21, 21, 47, 49, 44 and 43. The vertical motion of the needle rod 23 occurs with a balance weight 24, a bolt 27, a linkage rod 28 and a needle rod cam 29 by the rotary motion of the arm shaft 19. The cam boards 20 and 21 guide the rocking of the frame 22 in the workpiece movement direction in terms of the fixed shape with the rolls 47 and 49, the arm 44 and the rocking shaft 43.
Patent JP-H11348659-A (JP)
Title: On-vehicle image display device
Inventor: KATSUTA NOBORU
IPC: B60R1/00
Filed: 1999-04-07
Abstract: PROBLEM TO BE SOLVED: To provide a wide view of a periphery around a vehicle body without any dead angle by arranging a display image forming means cutting out images, which mutually compensate dead angles from respective camera image picking positions, from each of a plurality of images by a plurality of cameras and combining these images together. SOLUTION: In an image, its upper half is formed by simply shrinking image planes and connecting them together. Three backside image pick-up cameras are arranged with their optical axes held parallely to each other, and a rear camera is arranged in an intersection between view boundary lines of left and right cameras. In this way, an image by the rear image pick-up camera compensates a view area shielded by a vehicle body in images by the left and right backside image pick-up cameras.  The lower half of the image is formed by mutually superimposing the parts, in which the vehicle body is photographed, from images by the left and right side backside image pick-up cameras, taking out an image replacing the superimposed image in the slant line part from the rear image pick-up camera after area selection and deforming treatment, combining the images, and trimming, expanding, or shrinking the combined image.
Patent JP-S59225305-A (JP)
Title: Alignment apparatus in interference measuring machine
Inventor: KITABAYASHI JIYUNICHI
IPC: G01B9/02
Filed: 1983-06-06
Abstract: PURPOSE:To perform alignment adjustment automatically, rapidly and accurately, by a method wherein reference light and measuring light directed to a measuring part are partially separated to be condensed onto a predetermined plane in a spot shape while the spot position is detected to revolve a measuring specimen. CONSTITUTION:A holder 61 for holding a measuring specimen 4 is supported by a frame 64 which is, in turn, supported by a fixed frame 68 and the measuring specimen 4 can be revolved around an X-axis and a Y-axis by a first and a second revolving mechanisms. A laser beam source 1 is oscillated and a second shutter 14 is closed by a computer 12 while the spot coordinates zeta0, xsi0 of the reference light component obtained on the light receiving surface of a position sensor 9 are stored. A first shutter 13 is closed while the second shutter 4 is opened and the spot coordinates xsi1, zeta1 due to a measuring light component are taken in. xsi1-xsi0, zeta1-zeta0 are calculated to be compared with a minute amount (h) and the measuring specimen 4 is revolved by the first and the second revolving mechanisms to perform the correction of the spot position.
Patent JP-H06306186-A (JP)
Title: Friction material
Inventor: MISAWA NORIO
IPC: C08J5/14
Filed: 1993-04-27
Abstract: PURPOSE:To obtain the material improved in both heat resistance and abrasion resistance. CONSTITUTION:The material contains a silicon-modified phenolic resin as a binder and a carbonaceous filler treated with a titanate or a silane. Because this material contains the above-specified binder, the heat resistance and the cracking resistance after a heat history can be improved. Because the treated carbonaceous filler can improve the bonding force with a binder, the abrasion resistance does not lower.
Patent JP-H04226262-A (JP)
Title: Active tamper for bidirectional sorter
Inventor: POORA II RIIDO
IPC: B65H31/38
Filed: 1991-05-02
Abstract: PURPOSE: To improve the safety by providing a damper means capable of projecting a paper sheet in bins located above and below one bin adjacent to a fixed outlet for paper sheet, and in which paper sheets are fed without interference of the paper sheet in one bin. CONSTITUTION: A jogging device 20 is provided a damper member 22 abutting on one edge part of a paper sheet by intermittently driven by a solenoid drive part 24. The damper member 22 is prevented from being in the way in positioning a bin with the spring restoring force. An opposite edge part of a highest paper sheet placed in the bin last is pushed forward to the side positioning position or line by a moving force and/or impact in abutting the damper member 22 to one edge part of the paper sheet. The paper sheet is pushed forward to a positioning corner position in an area by the specified appropriate offset distance, for example, approximately 5 mm. The side positioning line is determined by a positioning perpendicular side stop wall or a finger.
Patent JP-H01271854-A (JP)
Title: Address converting circuit for virtual computer
Inventor: TAKAZAWA KAZUYOSHI
IPC: G06F12/10
Filed: 1988-04-22
Abstract: PURPOSE:To shorten the address converting time by adding previously the prefix value to the base address of a virtual computer and using this adding result to perform the prefix conversion at the address conversion. CONSTITUTION:The table index of a table index register 1 is added to the head address of a table head address register 3 and supplied to a PX converter 10 for check whether the prefix conversion is required or not. While a selector 8 selects the contents of a (PX+VM) register 5 and supplies them to the converter 10. When the prefix conversion is required, a specific bit of the input result of addition is replaced with the contents (PX+VM) given from the register 5 and stored in a real address register 11 as a real address. In case no prefix conversion is required, the result of addition is directly stored in the register 11. A selector 6 selects the contents of the register 11 and a selector 7 selects the base address of a VM base address register 4 to supply it to an adder 9. The unconverted value of the register 11 is added to the base address and stored in the register 11 as a real address.