baber/WOPTO huggingface dataset:
Patent CA-2267620-A1 (CA)
Inventor: HONEGGER ANNEMARIE
IPC: C12N1/19
Filed: 1997-07-16
Abstract: La présente invention concerne la modification des domaines de la superfamille des immunoglobulines (IgSF), de fragments d'IgSF et de protéines hybrides de ces derniers, et notamment la modification de dérivés d'anticorps, afin d'améliorer leur solubilité, et donc leur rendement et leur maniabilité. Les auteurs de la présente invention ont découvert que cette modification était possible en rendant plus hydrophile par modification, la zone comprenant l'interface comportant des domaines contigus au domaine d'IgSF dans un fragment plus grand ou une protéine d'IgSF complète, et qui est mise à nu dans le domaine d'IgSF. La présente invention concerne des séquences d'ADN codant des domaines ou des fragments d'IgSF modifiés et des protéines hybrides de ces derniers, des vecteurs et des hôtes contenant ces séquences d'ADN, des domaines ou fragments d'IgSF ou des protéines hybrides pouvant être obtenus en exprimant les séquences d'ADN dans des systèmes d'expression appropriés, et un procédé permettant de modifier des domaines d'IgSF afin d'améliorer leur solubilité, leur aptitude à être exprimés et leur maniabilité.
Patent CA-2268453-A1 (CA)
Title: Austenitic stainless steel having excellent sulfuric acid corrosion resistance and excellent workability
Inventor: SAGARA MASAYUKI
IPC: F28F19/06
Filed: 1998-08-10
Abstract: An austenitic stainless steel which consists, on a weight basis, of up to 0.05 % carbon, up to 1.0 % silicon, up to 2.0 % manganese, up to 0.04 % phosphorus, up to 0.01 % sulfur, 12-27 % nickel, 15-26 % chromium, 3.0-8.0 %, excluding 3.0 %, copper, 2.0-5.0 %, excluding 2.0 %, molybdenum, up to 1.0 % niobium, up to 0.5 % titanium, up to 5.0 %  tungsten, up to 1.0 % zirconium, up to 0.5 % aluminum, below 0.05 % nitrogen, up to 0.01 % calcium, up to 0.01 % boron, up to 0.01 % one or more rare earth elements, and iron and unavoidable impurities as the remainder. This steel is excellent in the resistance to sulfuric acid corrosion and workability.
Patent CA-2270094-A1 (CA)
Inventor: KIM CHANG H
IPC: G06F13/40
Filed: 1999-04-26
Abstract: An interface between a parallel backplane bus of a physical layer of a communication device and a higher layer of the device is provided in a manner compatible with a serial bus architecture such as IEEE 1394. The interface includes a parallel backplane physical layer controller having multiple receive data lines for receiving data from the backplane bus, and multiple transmit data lines for transmitting data to the backplane bus. A link layer controller is coupled to the parallel backplane physical layer controller, and communicates with the parallel backplane physical layer controller over a data bus. The parallel backplane physical layer controller can provide an effective data bandwidth which is greater than its operating clock rate. The parallel backplane physical layer controller may also be operative to support communications with the backplane bus using a plurality of different backplane bus widths, such as a single data bit bus width, a two data bit bus width, a four data bit bus width and an eight data bit bus width. The throughput data bandwidth of the interface can therefore be scaled by selecting one of the data bus widths supported by the parallel backplane physical layer controller.
Patent CA-2273419-A1 (CA)
Inventor: WILD HANS-PETER
IPC: B31B50/10
Filed: 1999-05-28
Abstract: The present invention relates to a method of producing foil bags, wherein at least two foils are supplied that serve as side foils of the foil bags, the foils are connected to each other and then cut into individual foil bags, wherein possibly existing differences in the amounts of foil materials provided by the at least two foils in the feed direction for a respective foil bag are eliminated by stretching the foil that provides the smaller amount of foil material for a foil bag, and to a bag-producing apparatus for performing the method.
Patent CA-2273457-A1 (CA)
Title: Gas-quenching cell
Inventor: PELISSIER LAURENT
IPC: C21D1/767
Filed: 1999-05-27
Abstract: A cell for gas-quenching a load, including guiding plates and a stirring element driven by an engine to cause a gas flow between the load and an exchanger. The stirring element is an adjustable pitch blade propeller.
Patent CA-2274469-A1 (CA)
Title: Serum-derived factor inducing cell differentiation and medical uses thereof
Inventor: PELED TONY
IPC: A61K35/16
Filed: 1997-12-01
Abstract: The present invention relates to a biologically active serum-derived composition of matter (SDF), having a low molecular weight, being electrically charged at acidic pH and having absorption at 280 nm. The molecular weight of said SDF was determined by electron spray mass spectrometry and is of 316 Da. SDF of the present invention or its complex with ceruloplasmin (CP) have several therapeutic properties. For example, SDF or its complex with CP is capable of inducing terminal cell differentiation of leukemic cells, which as a result, may lose their ability to proliferate and their ability for self cell renewal. Further, SDF or the complex with CP is capable of stimulating the proliferation of early, normal progenitor cells and inhibiting enhanced angiogenesis. In addition, SDF or its complex with CP is capable of ex vivo expanding normal stem and progenitor cells. The invention also relates to pharmaceutical composition comprising as active ingredient SDF or its complex and optionally further comprising pharmaceutically acceptable additives. Such pharmaceutical compositions may be for inhibiting enhanced angiogenesis, for inducing remission of tumors, for maintaining tumor remission, and for expanding hematopoietic normal stem and progenitor bone marrow transplants.
Patent CA-2274645-A1 (CA)
Title: Hybrid organic-inorganic planar optical waveguide device
Inventor: JOHNSON RONALD EDGAR
IPC: C03C17/00
Filed: 1997-12-12
Abstract: A planar optical device is formed on a substrate (12) and comprising an array of waveguide cores (14) and a cladding layer (16) formed contiguously with the cores. At least one of the array of waveguide cores (14) and the cladding layer (16) is an inorganic-organic hybrid material that comprises an extended matrix containing silicon and oxygen atoms with at least a fraction of the silicon being directly bonded to substituted or unsubstituted hydrocarbon atoms. In accordance with other embodiments of the invention, a method of forming an array of cores comprises the steps of preparing a core composition precursor material; partially hydrolyzing and polymerizing the material;  forming an array of waveguide cores under conditions effective to form an inorganic-organic hybrid material that comprises an extended matrix containing silicon and oxygen atoms with at least a fraction of the silicon being directly bonded to substituted or unsubstituted hydrocarbon atoms.
Patent CA-2276599-A1 (CA)
Title: Treatment of water by reverse osmosis
Inventor: GRAHAM WILLIAM
IPC: C02F1/48
Filed: 1998-01-09
Abstract: A desalinator is disclosed for removing dissolved solids from sea water or brackish water. The desalinator (10) comprising a casing (12) into which a pump (14) driven by a motor (16) pumps sea water or brackish water under pressure. A desalination cartridge (76) within the casing (12) includes semi-permeable material which acts as a reverse osmosis membrane and through which permeate is forced to separate it from the sea water or brackish water. The solids dissolved in the brackish water or sea water are retained in the salt retention passages of the cartridge (76). Three electrical coils (94, 96 and 98) encircle the cartridge (76) and are embedded in the walls of the casing (12). The coils are supplied with current from a supply (112) which is preferably a 50 Hertz, 380 Volt three phase supply. The coils are also connected by lines (108) to an adjustable frequency AC drive (110) which is in turn connected to the motor (16). The coils (94, 96 and 98) impose a magnetic field on the sea water or brackish water in the salt retention passages which enhances the rate at which water permeates through the reverse osmosis membrane and also inhibits fouling. The coils (94, 96 and 98) additionally act as chockes for the motor (16).
Patent CA-2277054-A1 (CA)
Title: Secure access method, and associated apparatus, for accessing a private data communication network
Inventor: NORDMAN MIKAEL
IPC: H04L29/06
Filed: 1998-01-09
Abstract: A method (152), and associated apparatus (10), for accessing a private IP  network (14) with a wireless host (32) by way of a wireless access network (52). Once authenticated and permitted access to the private 1P  network (14), the wireless host (32) becomes a virtual host of the private lP network (14). A wireless host identifier (WHI) is used to identify the wireless host (32). Permission to communicate by way of wireless access network (52) is confirmed by an authentication procedure (162). The WHI is thereafter provided to the private IP network (14). If the WHI is of a selected value, permission to access the private IP network (14) is granted. An IP address used to address data to the wireless host (32) is allocated by the private IP network (14) once access to the private IP network (14) is granted.
Patent CA-2279105-A1 (CA)
Title: Cable de liaison a isolation gazeuse, procede de fabrication et de pose d'un tel cable
Inventor: MOISSON-FRANCKHAUSER FRANCOIS
IPC: H02G1/06
Filed: 1999-07-27
Abstract: La présente invention concerne un câble à isolation gazeuse comportant une âme et une gaine extérieure. L'espace annulaire compris entre l'âme et l'enveloppe est rempli d'un gaz d'isolation, et l'âme est entourée par une chambre pneumatique qui présente après gonflage une forme cylindrique dont le diamètre est celui de la gaine du câble.
Patent CA-2279242-A1 (CA)
Title: New homogeneous olefin polymerization catalyst composition
Inventor: KAUHANEN JYRKI
IPC: C08F4/58
Filed: 1998-01-27
Abstract: Homogeneous olefin polymerization catalyst compositions prepared by contacting a) a metallocene of the general formula (1): (CpY q)m MX n Z o, wherein Cp is one of a mono- or polysubstituted, fused or non-fused, homo- (= iso-) or heterocyclic cyclopentadienyl ligand, Y is a substituent at the cyclopentadienyl ring and is one of an -OR, -SR, -NR2, -C(H or R)=, or -PR2 radical, M is a transition metal of Group 4 of the Periodic Table and bound to the ligand or ligands Cp in at least an .eta.5 bonding mode; X is bound to M and is one of a hydrogen, a halogen, a C1-C8 hydrocarbyl group, a C1-C8 hydrocarbylheteroatom (O, S, N, P) group or a tri-C1-C8 hydrocarbyl silyl group or two X form together with M a C4-C20 metallocyclic ring structure; Z is a bridge atom or group between two Cp ligands or between one Cp ligand and the transition metal M; q is 0-5; m is 1 or 2; m.q >= 1; o is 0 or 1; and n is 4-m-o, except when there is a bridge Z between two Cp ligands, in which case n is 4-m, and b) an aluminoxane of one of formulas (2), (OAlR')p (2 general), wherein each R' is the same or different and is a C2-C10 alkyl group; and p is an integer between 1 and 40.
Patent CA-2281028-A1 (CA)
Title: Flexible telecommunications switching network
Inventor: CHRIN CHRISTOPHER JAMES
IPC: H04L29/06
Filed: 1999-08-30
Abstract: Apparatus, and a method for flexibly switching telecommunication signals. A plurality of input bit streams are connected to a telecommunications switching network fabric element comprising a microprocessor system including memory.      The microprocessor system, under program control, performs switching and protocol conversion functions on the input streams in order to generate output streams. Advantageously, a single element is able to concurrently switch input signals in a variety of protocols, including circuit switching protocols, such as Pulse Code Modulation (PCM), and packet switching protocols, such as Asynchronous Transfer Mode (ATM) protocols and Internet Protocol, (IP). Where desirable, the microprocessor system can also control the protocol conversion of input signals in one protocol to output signals in another protocol.
Patent CA-2282341-A1 (CA)
Inventor: CRAFT LIBBEY S
IPC: A61P3/04
Filed: 1998-02-24
Abstract: This invention relates generally to a method for modulating the Hypothalamic-Pituitary-Adrenal Adipose Axis (HPAAA) in a mammal in need of such treatment by administration of a therapeutically effective amount of a leptin receptor ligand. More specifically, this invention relates to the use of leptin receptor agonists to treat disorders of the HPAAA, including the hyperglucocorticoidemia associated with Cushing's Syndrome, fasting, or otherwise-induced stress in obese or lean mammals in need of such treatment.  This invention also relates to the use of leptin receptor antagonists, or specific anti-leptin antibodies, to treat the hypoglucocorticoidemia associated with autoimmune or inflammatory conditions such as rheumatoid arthritis.
Patent CA-2283890-A1 (CA)
Inventor: MILBURN DOUGLAS I
IPC: F24J2/50
Filed: 1999-09-27
Abstract: An inorganic particulate, having strong absorption in the thermal infrared region of the radiative spectrum and low absorption in the solar or visible portion of the radiative spectrum, is combined with a plastic resin, to create a composite material. This composite is used in whole or in part to manufacture a honeycomb transparent insulation material, or is applied as a coating to a honeycomb transparent insulation material. The resulting honeycomb transparent insulation can have similar visible or solar light transmittance, and will have improved thermal radiant suppression relative to an identical honeycomb made of plastic resin only.
Patent CA-2286378-A1 (CA)
Inventor: VERNIN JACQUES
IPC: A23L27/10
Filed: 1998-05-12
Abstract: A composition which can be used in the cosmetic and therapeutic fields comprises one or more plant extracts with defined active ingredient titers, one or more individually microencapsulated essential oils, a buffer mixed with the microencapsules of essential oils and one or more pharmaceutically or cosmetically acceptable excipients which is contained within a capsule.
Patent CA-2286463-A1 (CA)
Inventor: KREJCAREK GARY E
IPC: C12M1/16
Filed: 1997-08-26
Abstract: This invention relates to devices and methods to quantitate bacteriophage. The method employs the use of a precipitable dye and a contrast-coloring dye to improve the visualization of viral plaques on a lawn of bacteria. A preferred device employs a water-hydratable powder, a precipitable dye and a contrastcoloring dye and the device includes a spacer sufficiently thick so that the cover over the device does not contact the bacteria growing in the substrate of the device.
Patent CA-2289798-A1 (CA)
Title: Modular concrete building system
Inventor: CANTARANO ROBERT A
IPC: E04B1/61
Filed: 1999-11-15
Abstract: A modular construction system and method of use for creating a concrete wall system (20) which has a wall system which complies with a modular construction system. The system uses wall form panels (32) having connectors (48) and structural tie plates (24). The wall form panels have interlocking protrusions (38) around the edges such that the panels are reversibly symmetric. The panels are specific lengths to minimize the number of panels required to achieve a set length. The structural tie plates have connectors (90) to tie in with the wall form panels and in addition carry and position reinforcement bars (26, 28) with the wall. The modular wall system ensures ease and integrity of alignment of the wall form panels by the self-aligning structural tie elements. In a preferred embodiment, a footing (114) is continuously integral with the wall. A heat retention cap form (33) allows for a more uniform cure temperature in adverse temperatures.
Patent CA-2290008-A1 (CA)
Inventor: KERECMAN NORMAN CLYDE
IPC: F16L9/16
Filed: 1999-11-17
Abstract: A pipe having a filament wound fiber preform and a method of producing the pipe is provided. First, the method involves creating a rigid preform by coating a fiberglass awing with an epoxy or a polyester resin; filament winding the fiberglass roving to form a structure having a sidewall defining openings through which a second resin is capable of penetrating; and curing the epoxy or polyester resin. Next, a second resin, such as dicyclopentadiene, is centrifugally cast or reaction injection molded around the preform so that the second resin encases the preform. Finally, the second resin is cured to form a pipe. This method permits the manufacture of large diameter reinforced pipe capable of withstanding high pressures.
Patent CA-2293056-A1 (CA)
Title: Polyether hydroxycarboxylate copolymers
Inventor: RODRIGUES KLEIN A
IPC: C08G65/22
Filed: 1999-12-22
Abstract: The invention provides novel polyether hydroxycarboxylate copolymers which are effective sequestering agents. The polyether hydroxycarboxylate copolymer when used in a cleaning composition enhances or "builds" the cleaning efficiency of the surfactant by inactivating hardness ions. In addition, the polyether hydroxycarboxylate copolymers assist in cleaning by dispersing and suspending soils to prevent the redeposition of soils. The polyether hydroxycarboxylate copolymer has the structure (see formula I) wherein M+ is a cation wherein M is independently selected from hydrogen, ammonia, alkali metals, alkaline earth metals, zinc, copper, organic amines, amino acids, and amino saccharides; R2 and R3 are independently hydrogen or a substituted or unsubstituted alkyl group having 1 to 4 carbon atoms; n is from about 2 to about 100; x1 and x2 are independently 0 or 1; a is from 0 to 99 mole percent; and b is from 100 to 1 mole percent, provided that (a + b) is 100 mole percent.
Patent CA-2301735-A1 (CA)
Title: Device for testing of diesel fuel
Inventor: KITCHING JOHN STEPHEN
IPC: G01N33/22
Filed: 1998-09-11
Abstract: A device for generating a series of output signals in relation to a rotating output shaft of a diesel fuel test engine having means for generating a series of engine signals, each engine signal occuring at a first angular orientation of the output shaft. Each output signal is generated at a second angular orientation of the output shaft. The device comprises an input for receiving the series of engine signals, means for measuring the angle of rotation of the output shaft relative to the occurrence of each engine signal, means for determining an angular interval between said first and second angular orientations of the output shaft, in the direction of rotation of the output shaft, and means for generating said output signal when the measured angle of rotation of the output shaft corresponds to said angular interval.
Patent CA-2302416-A1 (CA)
Inventor: WESTERBERG EUGENE R
IPC: F24C7/08
Filed: 1998-09-04
Abstract: A lightwave oven cooking method and apparatus using power and pulsed power applied to a plurality of high-power lamps which provide radiant energy in the electromagnetic spectrum and having wavelengths including the visible and near-visible ranges wherein irradiation is applied to the food by applying power to the lamps for a specified period of time without vaporizing all of the surface water on the food, and then applying reduced irradiation to the food to complete the cooking cycle without producing an overly browned surface which inhibits deep penetration of radiation in the near-visible and visible ranges. The reduced power can be at a reduced duty cycle which can be done in a sequence of one or more reducing steps in the duty cycle or a continuous reduction of the duty cycle of the power applied to the lamps. A change in color, in water vapor concentration emitted from the surface, in the food temperatures and/or in the generation of steam to a predetermined degree can be sensed to reduce power.
Patent CA-2302523-A1 (CA)
Title: Cross-linked particles
Inventor: STARLING SCOTT MATHEW
IPC: A61K9/52
Filed: 1998-08-28
Abstract: Cross-linked particles are provided that are useful for delivery of pharmaceutical agents. The particles comprise at least one polymeric compound and a spacer compound, where the polymeric compound and the spacer each comprise reactive carboxyl, hydrazidyl, amino and/or thiol groups. The particles are cross-linked via covalent linkage of the reactive groups on the polymer and spacer respectively. Compositions comprising pharmaceutical agents contained within the particles are disclosed. Methods for preparing the particles, for encapsulating pharmaceutical agents within the particles, and for using the particles for controlled release of the pharmaceutical agent within the patient also are provided.
Patent CA-2304287-A1 (CA)
Title: Elastomeric propylene polymers
Inventor: WENG WEIQUING
IPC: C08F4/42
Filed: 1998-11-12
Abstract: A thermoplastic elastomer is provided comprising a branched olefin polymer having crystalline sidechains and an amorphous backbone wherein at least 90 mole percent of the sidechains are isotactic or syndiotactic polypropylene and at least 80 mole percent of the backbone is atactic polypropylene. Additionally, a process is provided for producing a thermoplastic elastomer composition comprising: a) contacting, in solution, at a temperature from 90 °C to 120 °C propylene monomers with a catalyst composition comprising a chiral, stereorigid transition metal catalyst compound capable of producing isotactic or syndiotactic polypropylene; b) copolymerizing the product of a) with propylene and, optionally, one or more copolymerizable monomers, in a polymerization reactor using an achiral transition metal catalyst capable of producing atactic polypropylene; and c) recovering a branched olefin polymer.
Patent CA-2305136-A1 (CA)
Title: Sintered powder metal bodies and process for producing the same
Inventor: AMMA HIROYUKI
IPC: C22C33/02
Filed: 1998-10-06
Abstract: A process for producing a sintered powder metal body is disclosed. A powdery mixture is prepared by blending a graphite powder in amount of not less than 0.3 % by weight with an iron based metal powder (51). The powdery mixture is compacted into a preform having a density of not less than 7.3 g/cm3 (52). The preform is sintered at a temperature of 800-1000 ~C to form the sintered powder metal body having a predetermined structure (53). The predetermined structure of the sintered powder metal body includes iron based metal particles and graphite particles retained between the iron based metal particles.
Patent CA-2306820-A1 (CA)
Title: Improved methods for producing factor viii proteins
Inventor: DALBORG JOHANNA
IPC: C12N15/09
Filed: 1999-03-11
Abstract: Methods are provided for purification of Factor VIII polypeptides by immunoaffinity chromatography and ion exchange chromatography, in which the eluate from the immunoaffinity column is diluted with a solution comprising higher salt concentration, or lower non-polar agent concentration than that of the elution solution, prior to passing the diluted solution through the ion exchange column. The methods result in improved purification without significant yield loss.
Patent CA-2308606-A1 (CA)
Title: Neisserial antigens
Inventor: RAPPUOLI RINO
IPC: A61P31/04
Filed: 1998-10-09
Abstract: The invention provides proteins from Neisseria meningitidis (strains A and B) and from Neisseria gonorrhoerae including amino acid sequences, the corresponding nucleotide sequences, expression data, and serological data. The proteins are useful antigens for vaccines, immunogenic compositions, and/or diagnostics.
Patent CA-2309481-A1 (CA)
Inventor: EGGELING LOTHAR
IPC: C12N15/77
Filed: 2000-05-26
Abstract: The invention provides a process for the fermentative preparation of L-amino acids using coryneform bacteria, in which the subunit carrying the biotin-carboxyl carrier protein domain and the biotin-carboxylase domain of the nucleotide sequence encoding the enzyme acetyl-CoA carboxylase (accBC gene) is amplified, in particular is overexpressed.