baber/WOPTO huggingface dataset:
Patent FI-852990-L (FI)
Inventor: DESAI BIPINCHANDRA NANUBHAI
IPC: C07D207/40
Filed: 1985-08-02
Abstract: This invention encompasses compounds of the formulaand pharmaceutically acceptable acid addition salts thereof wherein n is 2 or 3 and R and R, are n-propyl, isopropyl, or R, and R, together with N form a 2,6-dimethyl-1-piperidinyl group. The compounds of this invention are useful as antiarrhythmic agents.
Patent IE-791107-L (IE)
Title: Anaerobic compositions
IPC: C09J4/02
Filed: 1979-08-08
Abstract: Anaerobic compositions containing strong acid impurities and/or strong acid precursors are neutralized and stabilized against the degrading effects of pH decrease during storage by adding about 0.1 to about 10 percent by weight of the total composition of an epoxy.
[US4245077A]
Patent IE-781242-L (IE)
Title: Process for the preparation of benzoylureas.
IPC: A01N47/34
Filed: 1978-06-21
Abstract: Benzoylureas are prepared from a benzamide, an alkyllithium, a phenyl chloroformate, and an amine. Two reaction sequences are described. The benzoylureas obtained by the process are useful as insecticides.
[US4133956A]
Patent IE-901438-L (IE)
Title: Hydroxyalkanamine derivatives
IPC: C07C213/02
Filed: 1990-04-23
Abstract: Compounds of formula (I), wherein R<1> is hydroxy or C1-10alkyl, and in vivo hydrolysable esters and salts thereof are described as agents for the treatment of obesity and related conditions. Processes for their preparation and intermediates are described.
Patent IE-821476-L (IE)
Title: N-aryl-piperazinealkanamides
IPC: C07D487/04
Filed: 1982-06-22
Abstract: Novel N-aryl-piperazinealkanamides, having particular substituents attached to one of the carbon atoms of the piperazine ring, which compounds are useful to protect hearts from myocardial injury caused by ischaemia, anoxia or hypoxia.
[US4766125A]
Patent IE-831772-L (IE)
Title: Substituted (10h-phenothiazine-10-yl) propyl-1-piperazine¹derivatives
IPC: C07D279/26
Filed: 1983-07-27
Abstract: Substituted (10H-phenothiazin-10-yl)propyl-1-piperazines of the formula    <IMAGE>  I  wherein R1, R2, R3, A, X, m, n and s are as hereinafter set forth, are described. The compounds of formula I, which contain a piperazine moiety combined by an ether linkage to different phenolic moieties, are useful as orally active long lasting antipsychotic agents.
Patent IE-38371-L (IE)
Title: Reminieralisation of dental enamel
IPC: A61K6/00
Filed: 1973-10-12
Abstract: 1452125 Remineralizing teeth PROCTER & GAMBLE CO 12 Oot 1973 [13 Oct 1972] 47800/73 Heading A5B A pack for remineralizing teeth comprises (A) a cation in water-soluble form which cation is capable of forming an insoluble preciptate and (B) an anion in water-soluble form which is capable of forming with the cation an insoluble precipitate adapted to remineralize subsurface dental enamel, one of both of components (A) and (B) containing a flavouring agent, the components being compatible with the oral environment and being such as to have a pH from 3 to 10 in solution. In use, the two components are applied sequentially to the tooth, the remineralizing precipitate being thereby formed in situ. Cations specified are calcium, indium, barium, lanthanium, manganese, lead, tin, zinc, zirconium, iron, titanium, vanadium, cadmium, magnesium, aluminium, strontium, cesium, samarium, praseodymium, neodymium, nickel, lithium (with phosphate), molybdenum, vanadium, tungsten. Anions specified are fluoride, phosphate, fluorophosphate, silicofluoride, molybdate, sulphate, tungstate, 8-hydroxyquinolate, tartrate, sorbate, carbonate, iodate, stearate, hydroxide, palmitate, myristate, laurate, oxalate, decyl sulphonate, lauryl sulphonate, myristyl sulphonate, cetyl sulphonate, octadecyl sulphonate, silicate, hexadecyl sulphonate, aluminate. Physical forms of the two components specified are: mouthwashes, toothpastes, beverages, candy drops, foods, toothpowders, chewing gum, toothpaste in which one component is encapsulated and a multilayer lozenge.
[GB1452125A]
Patent IE-881909-L (IE)
Title: Abrasive polycrystalline diamond body
IPC: E21B10/56
Filed: 1988-06-23
Abstract: Temperature resistant abrasive polycrystalline diamond bodies are described, intended for use as tools in various mechanical operations like turning, milling, drilling, sawing and drawing, having different additions, i.e. amount and composition, of binding, fluxing, catalyst metals at different distances from the working surface. Preferably the metal concentration of the polycrystalline diamond body is decreasing towards the working surface while the metal composition is varied in a way that gives a mechanically stiffer matrix that also has a lower thermal expansion. In one embodiment the diamond body is high pressure-high temperature-bonded to a supporting body (14), e.g. of cemented carbide, in order to facilitate the clamping of the tool. In another embodiment the diamond body is brazed to a supporting body (14) or used in a surface-set rock drill bit, i.e. held by a braze metal. Especially good results have been obtained if the hard polycrystalline diamond body comprises three different homogeneous diamond layers (11, 12, 13) on top of each other, each layer (11, 12, 13) having its special amount and composition of relatively low-melting binding metal. These three diamond layers (11, 12, 13) are bonded to each other and to the supporting body (14), if any, by using intermediate layers (21, 22, 23) of the thickness 3-300/um, consisting of more high-melting metals or other materials like nitrides or borides, etc. in order to lock in the low-melting binding metals and to prevent diffusion of these metals between the different diamond layers (11, 12, 13) and between the supporting body (14) and the nearest diamond layer (13).
[EP0297071A1]
Patent IE-38421-L (IE)
Title: N-substituted-9-hydroxybenzomorphan derivatives.
IPC: C07C45/68
Filed: 1973-10-25
Abstract: 1431705 N-substituted benzomorphan derivatives BRISTOL-MYERS CO 26 Oct 1973 [26 Oct 1972] 50039/73 Heading C2C [Also in Division A5] Novel compounds L: (in which R<SP>1</SP> is CH#C-CH 2 -; CH 2 =CH-CH 2 -, (CH 3 ) 2 C=CH-CH 2 -, ClCH=CH-CH 2 - or a radical of formula in which R<SP>6</SP> is H or CH 3 ; R<SP>2</SP> is H, 1-6C alkyl, 2-6C acyl, 3- or 4-pyridyl-carbonyl, N-oxidopyridyl-3-carbonyl, #-morpholinoethyl, methoxymethyl, benzylcarbonyl, orN-oxido-pyridyl- 4-carbonyl; R<SP>5</SP> is H, 2-6C acyl, trichloroacetyl or cinnamoyl; R<SP>3</SP> is H, CH 3 , C 2 H 5 , n-C 3 H 7 , allyl or propargyl; and R<SP>4</SP> is 1-6C alkyl, 3-7C alkenyl or alkynyl or a radical in which n is 1-6 and R<SP>10</SP> is H, Cl, Br, F, NO 2 , 1-6C alkyl or alkoxy or NH 2 ) and salts thereof are prepared by (A) reacting a compound XXXXIII: (in which R<SP>7</SP> is 1-6 alkyl) with a compound (in which X is Cl, Br or iodo, Z is CO or CH 2 and W is as defined for R<SP>1</SP> above but in which the alpha-methylene group is missing) in the presence of a base to give a compound XXXXIV: (B) selectively reducing the carbonyl group of compound XXXXIV if Z is CO to produce a compound XXXXV: and when it is desired to produce compounds L in which R<SP>2</SP> is other than R<SP>7</SP> (C) cleaving the ether function of compound XXXXV to give a compound L where R<SP>2</SP> is H and, if desired, converting, by known methods, the compound L where R<SP>2</SP> is H to a compound L where R<SP>2</SP> is other than H. Certain of the reactions described in the examples are depicted in charts I to VII: (Continued on next page.)
[GB1431705A]
Patent IE-791943-L (IE)
Title: Phenyl quinolizidines.
IPC: A61K/
Filed: 1979-10-12
Abstract: Phenyl-quinolizidines of the formula <IMAGE> I wherein X, Y, R1 and R2 are as hereinafter set forth, are described. The compounds of formula I are useful as antipsychotics, antiemetics and analgesics.
[US4236010A]
Patent IE-892444-L (IE)
Title: Drill bit
IPC: C04B37/02
Filed: 1989-07-27
Abstract: The invention relates to a drill bit of the percussion type having a bit body (10) of steel the front working portion of which is provided with at least one slot (11) in which an insert (12) is attached by brazing means. In order to substantially reduce the braze stresses and thereby enable usage of cemented carbide with higher hardness and reduced need of regrinding the drill bit of the invention has been equipped with a number of support plates (13) that have uniform thickness whilst being much thinner than the insert (12) said support plates consisting of cemented carbide or a metal alloy with a coefficient of linear expansion which, for temperatures below 500 DEG C is substantially smaller than same coefficient for steel and the braze metal whilst being approximately the same as the same coefficient for the insert (12).
Patent IE-873057-L (IE)
Title: Compositions and method for treatment of cancer using¹monoclonal antibody against gd3 ganglioside together eith¹il-2
IPC: A61K38/00
Filed: 1987-11-12
Abstract: Cell surface gangliosides are presumed to play a role in cell growth and differentiation. Using monoclonal antibodies directed against GD3, a disialoganglioside expressed predominantly by cells of neuroectodermal origin, we have found that GD3 is expressed by a subpopulation of cells of the immune system including: a) fetal thymocytes in subcortical regions and near vessels, 2) lymph node lymphocytes in interfollicular areas and near vessels, and 3) a small subset of T cells in the peripheral blood. Mouse monoclonal antibodies (two IgGs, one IgM and F(ab')2 fragments) reacting with GD3 were found to stimulate proliferation of T cells derived from peripheral blood. Proliferation induced by binding to GD3 could be augmented by exogenous IL-2, PMA, PHA or Protein A.
[EP0267615A2]
Patent IE-843149-L (IE)
Title: Synergistic pharmaceutical compositions
IPC: A61K31/195
Filed: 1984-12-07
Abstract: The invention relates to a synergistic pharmaceutical composition, which comprises as an active ingredient a combination of 1-phenylalanine and (-)-deprenyl [(-)-N-(1-phenylisopropyl)-N-methyl-N-propinylamine hydrochloride] and optionally carbidopa [3-(3,4-dihydroxyphenyl)-2-hydrazino-2-methyl-propionic acid monohydrate] or benzerazide [N-(DL-seryl)-N'-( 2,3,4-trihydroxybenzyl)-hydrazine] in association with conventional inert, non-toxic solid or liquid pharamaceutical carriers. The invention further relates to the preparation of these compositions and to the use thereof for the treatment of depressive symptoms.
[US4880833A]
Patent NO-800184-L (NO)
Inventor: DEWAEGHENEIRE GABRIEL
IPC: G08B13/12
Filed: 1980-01-25
Abstract: This invention relates to a security fence including at least one tensioned wire connected to a detector for sensing movement of the wire. The detector comprises a movable element which sealingly separates two chambers in such a manner that any movement of the sealing element produces a change in volume of at least one of the chambers, which one chamber is connected to a pressure-sensitive switch actuator. Preferably, the said detector comprises an air cylinder with a piston which constitutes the said sealing element and is connected to the said wire.
Patent NO-810901-L (NO)
Title: Justeringsanordning ved siltrykkemaskin.
Inventor: MUELLER GEORG
IPC: B41F15/10
Filed: 1981-03-16
Abstract: Oppfinnelsen angår en justeringsanordning ved en silketrykkemaskin. Ved fint raster og store formater skal sjablonbildet overføres til trykkunderlaget, f.eks. en.ledeplate, uten forskyvning av trykkbildet. Til dette tjener et målemikroskop (5) som er festet på en stangmekanisme ovenfor silketrykkebordet. Stangmekanismen setter seg sammen av en første stangmekanisme (2) som via et glidehode (3) er forbundet med en annen stangmekanisme (4) som er bevegelig loddrett på den første stangmekanisme . og parallelt med silketrykkebordet.
Patent NO-833365-L (NO)
Inventor: MCGEOCH IAN LACHLAN MACKAY
IPC: G01S13/78
Filed: 1983-09-19
Abstract: The present invention relates to a method of and apparatus for identifying a selected radar target in which an initial interrogation radar pulse is transmitted from a base station and received at the selected target x and any other such radar targets y z at which it is applied to a respective responder causing the responder to generate a monitor response signal x1, x2, y1, y2, z1, z2 with a pulse separation tr not less than the duration of an identification signal. Each said target x, y, z receives one or more monitor response signals x1, . . . z2 from the other radar target responders. Any monitor response signals y1, y2, z1, z2 received partly overlapping the monitor response signal x1, x2 of any of said radar targets are detected and a garble flag means set thereat. The base station detects any garbling between monitor response signals received from the selected radar target and any other such radar target whereupon it transmits a suppression radar signal to suppress radar targets y, z having different, garble flag conditions from the selected radar target x until all the other radar targets have been suppressed y, z and then transmits at least two, identification signal portion seeking, interrogation radar signals and processes the identification signal portions received from the unsuppressed selected radar target so as to produce a signal containing all of the data concerning the specific individual identity of said selected radar target x.
Patent NO-834401-L (NO)
Title: Pyrazolo(4.3-b)(1.4)oxasiner, fremgangsmaate til deres fremstilling og deres anvendelse som legemiddel
Inventor: FRUCHTMANN ROMANIS
IPC: C07D498/04
Filed: 1983-11-30
Abstract: Pyrazolo[4,3-b][1,4]oksaziner med den generelle formel I i deres isomere former Ia og Ib såvel enkeltvis som også i blanding. hvori R og R^ blant annet kan bety^ hydrogen, metyl og/eller fenyl, 4-klorfenyl, 4-metoksyfenyl,. R 2 kan blant annet bety hydrogen, met;•eller etyl og. . R3 kan blant annet bety hydrogen, metyl, 3,4-diklorbemzyl, 2-fenoksyetyl, B-naftoksyetyl, benzyloksykarbonyl, formyl, acetyl og karboksymetyl og. R 5 kan blant annet bety hydrogen, metyl, propyl og isopropyl.Det omtales også fremgangsmåte til deres fremstilling. og deres anvendelse som legemiddel, spesielt deres anvendelse som lipoksygenasehemmere, legemidler som inneholder disse og deres fremstilling.
Patent NO-842856-L (NO)
Inventor: BUREN KURT JOHNNY ANDREAS
IPC: C22B13/00
Filed: 1984-07-12
Abstract: The invention relates to a method for recovering lead and lead-alloying elements from bettery-type lead waste products, and fractions thereof, such as battery mud, and similar oxidic-sulphatic materials.In accordance with the method, the waste products, together with a solid reduction agent, are introduced to a furnace in which the contents thereof can be vigorously agitated. The amount of solid reduction agent charged is selected so as to ensure the chemical reduction of substantially all the non-metallic lead contained by the waste products, and the alloying elements present therein. The material charged to the furnace is heated to a temperature of between about 1050°C and 1250°C, while vigorously agitating the furnace contents, so as to melt, split-off and chemically reduce the waste products, to form a lead melt containing the aforementioned alloying elements.The furnace used is preferably a top-blown rotary converter of the Kaldo type, in which the furnace contents can be agitated by rotating the furnace.
Patent NO-900234-L (NO)
Inventor: OLSON GARY LEE
IPC: C07D403/08
Filed: 1990-01-16
Abstract: [(5-Oxo-2-pyrrolidinyl)methyl]cyclohexaneacetamides of the formula   <CHEM> wherein R1 is hydrogen, lower alkyl or aryl-lower alkyl; R2 is hydrogen, lower alkyl, aryl, aryl-lower alkyl, <CHEM> wherein R5 and R6 are hydrogen, lower alkyl or aryl-lower alkyl; R3 and R4, independently, are hydrogen, lower alkyl or aryl-lower alkyl;  and enantiomers, diastereomers, and racemates thereof, and, when R2 <CHEM> pharmaceutically acceptable acid addition salts thereof exhibit cognitive enhancement and antiamnestic activity and are therefore useful, for example, in treating memory deficits associated with Alzheimer's disease or age-associated memory impairment.
Patent NO-914989-L (NO)
Inventor: WHEATLEY JOHN A
IPC: G02B5/08
Filed: 1991-12-17
Abstract: A multilayered, highly reflective polymeric body comprising at least two types of optical layers which is thermoformable and capable of being fabricated into films, sheets and a variety of parts while maintaining a uniform reflective appearance is provided. The reflective polymeric body includes at least first and second diverse polymeric materials having a sufficient number of layers of the first and second polymeric materials such that at least 30 percent of light incident on the body is reflected. A portion of the layers have optical thicknesses between 0.09 and 0.45  mu m, and the remaining layers have optical thicknesses of not greater than 0.09  mu m or not less than 0.45  mu m. The first and second polymeric materials differ from each other in refractive index by at least about 0.03. The reflective body may be fabricated into sheets, mirrors, noncorroding metallic appearing articles and parts, reflectors and reflective lenses.
Patent NO-920644-L (NO)
Inventor: STELTENKAMP ROBERT J
IPC: A61K8/36
Filed: 1992-02-18
Abstract: N-monosubstituted neoalkanamides of 11 to 14 carbon atoms wherein the substituent on the amide nitrogen is cyclic (aromatic or cycloaliphatic, such as aryl or cycloalkyl) and of at least five carbon atoms, have been discovered to be insect repellent, providing that any aromatic substituent is unsubstituted at the ortho position and that when the neoalkanoyl moiety is pivaloyl the total number of carbon atoms in the N-cyclic neoalkanamide is at least 12. Such neoalkanamides are useful as repellents against cockroaches, including American, German and Oriental cockroaches, and are also effective against mosquitoes (both Anopheles and Aedes), black flies and carpenter ants, and to some extent against deer ticks. They may be applied to areas, locations and items which are desirably to be kept free of such insects, with applications being direct or of solutions or emulsions thereof, preferably by spraying, or in detergent compositions or other products to be applied to such areas, etc. Because the described neoalkanamides are desirably substantive to surfaces and are usually in liquid state, they give long lasting repellency to such areas, etc., and tests have shown them to be sufficiently long lasting.
Patent NO-921947-L (NO)
Inventor: CAMERON JANET MARY
IPC: A61K/
Filed: 1992-05-15
Abstract: Combinations comprising a compound of formula (1) <CHEM> or a pharmaceutically acceptable derivative thereof and an inhibitor of HIV replication, pharmacetical formulations thereof and their use in the treatment of HIV infections. <IMAGE>
Patent NO-932687-L (NO)
Inventor: GEERLINGS MAURITS WILLEM
IPC: G01N33/532
Filed: 1993-07-26
Abstract: The present invention relates to the field of site directed therapy. More specifically it relates to site directed radio therapy. It provides a method for production of radioimmuno conjugates and an apparatus for radioimmuno therapy. The method, conjugates and apparatus can be practicalized without the need for radioactive shielding and/or airtight facilities. Without these restrictions the invention provides a simple and efficient means of therapy at the bed-side of the patient.
Patent NO-932978-L (NO)
Inventor: MAEYRAENEN TARMO
IPC: G01N29/02
Filed: 1993-08-20
Abstract: Method and device for monitoring of the composition of a flowing gas. An oscillation of sound frequency is applied to the gas flow pipe (10) downstream and upstream, and the travel times (t1, t2) of the monitoring sound over a certain measurement distance (L) downstream and upstream are detected. The sound speed (c) or a quantity representing same is determined on the basis of said travel times (t1, t2). This speed (c) is mainly dependent on the average molecular weight of the gas to be monitored. The temperature (T) of the flowing gas is measured, and on the basis of the measurement of temperature, the sound speed that has been reduced to a certain reference temperature T0 is determined from the formula c0 = c .  2ROOT (T0/T), which is applicable to an ideal gas and wherein T = absolute measured temperature of the gas, T0 = chosen absolute reference temperature, c = measured sound speed, and c0 = sound speed reduced to the reference temperature, or by using a corresponding more realistic formula. When the reduced temperature (c0) differs from its range of expected values (c1...c2), an alarm signal or control signal is given. Alternatively, the limits (C1, C2) of the range of expected values can be reduced to temperature.
Patent NO-934501-L (NO)
Title: Karboksylsyrederivater, legemidler inneholdende disse forbindelser, og fremgangsmåte for deres fremstilling
Inventor: HIMMELSBACH FRANK
IPC: A61K31/4465
Filed: 1993-12-09
Abstract: Oppfinnelsen angår karboksylsyrederivater med den generelle formel. hvor. A til E og Ra er som definert i krav 1, deres tautomerer, deres stereoisomerer innbefattet deres blandinger og deres salter, spesielt deres fysiologisk akseptable salter med uorganiske eller organiske syrer eller baser, som oppviser verdifulle farmakologiske egenskaper, spesielt aggregasjons-hemmende virkninger, legemidler som inneholder disse for-bindelsene og fremgangsmåter for deres fremstilling.
Patent NO-940661-L (NO)
Inventor: CHISARI FRANCIS V
IPC: A61P1/16
Filed: 1994-02-25
Abstract: Peptides are used to define epitopes that stimulate HLA-restricted cytotoxic T lymphocyte activity against hepatitis B virus antigens. The peptides are derived from regions of HBV nucleocapsid, envelop, polymerase and the transcriptional transactivator X protein, and are particularly useful in treating or preventing HBV infection, including methods for stimulating the immune response of chronically infected individuals to respond to HBV antigens. Pharmaceutical compositions and hepatitis B vaccines which comprise the peptides and physiologically acceptable carriers can be employed in conjunction with other HBV vaccinss to provide more effective immunity against the disease. Methods for identifying individuals who are particularly susceptible to developing chronic HBV infection and who can be targeted for treatment by the CTL peptides are also provided.
Patent NO-941157-L (NO)
Inventor: SOETE GERARD DE
IPC: B01D53/56
Filed: 1994-03-29
Abstract: PCT No. PCT/EP92/02173 Sec. 371 Date Jun. 22, 1994 Sec. 102(e) Date Jun. 22, 1994 PCT Filed Sep. 18, 1992 PCT Pub. No. WO93/06916 PCT Pub. Date Apr. 15, 1993.A process for purifying a gas containing nitrogen monoxide to remove nitrogen monoxide therefrom, includes adjusting oxygen content of the gas to provide a quantity of oxygen which is at least equal to a stoichiometric quantity which is necessary in order to oxidize the nitrogen monoxide contained in the gas to nitrogen dioxide; contacting the gas, substantially in the absence of any liquid, with an alkali metal pyrosulphite which is a solid and which is employed in a quantity which is sufficient to convert the nitrogen monoxide contained in the gas to alkali metal nitrite and alkali metal nitrate; and removing the alkali metal nitrite and the alkali metal nitrate from the gas.
Patent NO-942641-L (NO)
Title: Inhibisjon av fosfatidylinositol 3-kinase med wortmannin og analoger derav
Inventor: BONJOUKLIAN ROSANNE
IPC: A61K31/58
Filed: 1994-07-14
Abstract: Wortmannin og visse analoger derav er inhibitorer av fosfatidylinositol 3-kinase. Forbindelsene er spesielt nyttige for inhibering av fosfatidylinositol 3-kinase i pattedyr og for behandling av fosfatidylinositol 3-kinase-avehengige tilstander, spesielt neoplasmer, i pattedyr.
Patent NO-953503-L (NO)
Title: Konsentrerte rengjöringsblandinger
Inventor: EVERS MARC FRANCOIS THEOPHILE
IPC: C11D1/72
Filed: 1995-09-06
Abstract: Stabile og klare konsentrerte rengjøringsblandinger omfatter minst ett kortkjedet overflateaktivt middel. De kortkjedede overflateaktive midler mulig- gjør blanding av stabile blandinger uten behov for ytterligere stabilisatorer og de kortkjedede over- flateaktive midler er effektive ved rengjøring, spesielt ved rengjøring av overflate med fettsmuss.