baber/WOPTO huggingface dataset:
Patent NZ-555827-A (NZ)
Title: Use of an rauwolfia alkaloid such as reserpine for treating depression and depressive mood disorders
Inventor: DELACK ELAINE A
Filed: 2007-06-13
Abstract: Disclosed is a composition for treatment of depression and other depressive mood disorders, said composition comprising: reserpine for increasing the catalytic activity of MAO-A, so as to increase synaptic metabolism of serotonin to 5-HIAL; a caffeine compound for compensating for an antihypertensive effect of said reserpine; and a transdermal cream in which said reserpine and caffeine compound are combined for simultaneous transdermal application to a patient. Also disclosed is a use of a compound that increases the catalytic activity of MAO-A, so as to increase synaptic metabolism of serotonin to 5-HIAL, for the manufacture of a medicament for the treatment of depression and depressive mood disorders, wherein the compound comprises a rauwolfia alkaloid such as reserpine or a reserpine analogue.
Patent NZ-561004-A (NZ)
Title: Pharmaceutical forms comprising vardenafil with improved pharmacokinetic properties
Inventor: SERNO PETER
IPC: A61K9/22
Filed: 2006-02-16
Abstract: Disclosed is a drug formulation comprising vardenafil in the form of a salt with an acid or vardenafil with an acid, and sugar alcohols, which disintegrates rapidly in the mouth and is characterized in that at least 80% of the vardenafil dose in the substance form employed dissolves at 25°C in 10 ml of physiological saline and the rate of release from the drug formulation in 900 ml of physiological saline within the first 5 minutes in the USP pedal stirrer apparatus at 50 rotations per minute at 37°C is at least 70%.
Patent NZ-562182-A (NZ)
Title: Method and apparatus for anti-sparseness filtering of a bandwidth extended speech prediction excitation signal
Inventor: VOS KOEN BERNARD
IPC: G10L25/90
Filed: 2006-04-03
Abstract: A method of generating a highband excitation signal is disclosed. The method includes generating a spectrally extended signal by extending the spectrum of a signal that is based on an encoded lowband excitation signal; and performing anti-sparseness filtering of a signal that is based on the encoded lowband excitation signal. The highband excitation signal is based on the spectrally extended signal, and the highband excitation signal is based on a result of said performing anti-sparseness filtering.
Patent NZ-562496-A (NZ)
Title: Process for the reduction or removal of permanganate reducing compounds during production of acetic acid
Inventor: ZINOBILE RAYMOND J
IPC: C07C51/12
Filed: 2006-04-06
Abstract: Disclosed is a process for the reduction and/or removal of permanganate reducing compounds (PRC's) formed in the carbonylation of a carbonylatable reactant to produce a carbonylation product comprising acetic acid, comprising the steps of: a) separating the carbonylation product to provide a vapor overhead stream comprising acetic acid and a less volatile catalyst phase; b) distilling the vapor overhead stream to yield a purified acetic acid product and a low boiling overhead vapor stream comprising methyl iodide, water, acetic acid, methyl acetate, and at least one PRC; c) condensing the low boiling overhead vapor stream and biphasically separating it to form a condensed heavy liquid phase and a condensed light liquid phase; d) distilling the condensed light liquid phase in a single distillation column to form a second vapor phase stream overhead and a higher boiling liquid phase residuum, wherein the second vapor phase stream is enriched with PRC's with respect to the condensed light liquid phase e) optionally removing a sidestream comprising methyl acetate from the distillation column of step (d), wherein the higher boiling liquid phase residuum and the sidestream are cumulatively enriched with methyl acetate with respect to said second vapour phase stream; and f) condensing the second vapor phase stream and extracting the condensed stream with water to obtain an aqueous acetaldehyde stream comprising PRC and a raffinate comprising methyl iodide. Also disclosed is a carbonylation product produced by the above process.
Patent NZ-562536-A (NZ)
Title: Shelter means for trees or other plants
Inventor: BLOXWICH MARK EDWARD
IPC: A01G13/02
Filed: 2007-10-10
Abstract: A tree guard comprises a flexible material wrapped around and fastened to a helical spring coil frame, thus defining a tube. The tree guard further comprises a support post and securing means for connecting the support post to the tube. The securing means is preferably releasably connectable to the support post, and the point of connection between the support post and securing means is preferably adjustable.
Patent NZ-569001-A (NZ)
Title: System and method for storing items and tracking item usage
Inventor: NGUYEN THUY T
IPC: G16H40/63
Filed: 2006-12-06
Abstract: A system for storing items and tracking item usage is disclosed. The system includes: a drawer (16) with multiple storage spaces (40) adjustable to accommodate various sized items; an input means for inputting user-modifiable drawer configuration information and user-modifiable storage space location information; a control unit in operable communication with the drawer (16) and programmed to receive inputs from a user to adjust the configuration of the drawers, including locations of the storage spaces; a memory in operable communication with a processor (20) to store storage-space-specific information and item-specific information, the storage-space-specific information including storage space location information and drawer configuration information; and a display screen in communication with the control unit, which is configured to display an image representative of the storage-space-specific information stored by the control unit.
Patent NZ-579483-A (NZ)
Title: Aminopyridines useful as inhibitors of protein kinases
Inventor: JIMENEZ JUAN-MIGUEL
IPC: A61P25/28
Filed: 2008-03-10
Abstract: Disclosed are 1H-pyrazolo[3,4-b]pyridine derivatives or a pharmaceutically acceptable salt thereof as represented by the general formula (I), wherein: Ht is a pyrazolo[3,4-b]pyridine ring of the formula I-c, wherein any substitutable carbon in ring I-c is optionally substituted with -R10; Ring D is phenyl, wherein the phenyl is optionally substituted with 1-5 R5 groups; Z1 is N; each RX, RY, and RZ are independently H, halo, or aliphatic, wherein the aliphatic is optionally substituted with 1-5 groups selected from halo, -CN, and -OR; and wherein the remaining substituents are as define herein. Further disclosed are representative compounds such as N-(6-(2-chlorophenyl)-4-(trifluoromethyl)pyridin-2-yl)-5-fluoro-1H-pyrazolo[3,4-b]pyridin-3-amine, N-(6-(2-chlorophenyl)-4,5-dimethylpyridin-2-yl)-5-fluoro-1H-pyrazolo[3,4-b]pyridin-3-amine, N-(6-(2-chlorophenyl)-4-methyl-pyridin-2-yl)-5-fluoro-1H-pyrazolo[3,4-b]pyridin-3-amine, N-(6-(2-chlorophenyl)-3,4-dimethyl-pyridin-2-yl)-5-fluoro-1H-pyrazolo[3,4-b]pyridin-3-amine and N-(6-phenyl-4,5-dimethyl-pyridin-2-yl)-5-fluoro-1H-pyrazolo[3,4-b]pyridin-3-amine. Further disclosed is a composition which comprises a compound as defined above and a pharmaceutically acceptable carrier, adjuvant, or vehicle for the treatment of a disease or condition selected from diabetes, osteoporosis, Alzheimer's disease, Huntington's disease, Parkinson's disease, AIDS-associated dementia, bipolar disorder, amyotrophic lateral sclerosis (ALS, Lou Gehrig's disease), multiple sclerosis (MS), schizophrenia, leukocytopenia, stroke, and rheumatoid arthritis.
Patent NZ-583803-A (NZ)
Title: Agents with angiogenic and wound healing activity
Inventor: JOHNSON KERYN
IPC: C07K1/14
Filed: 2008-09-05
Abstract: Provided is the use of a PB2 crystallin protein in the manufacture of a medicament for treating a wound or ischemic or hypoxic tissue in a mammalian subject in need thereof, or an angiogenic fragment of the protein. Further provided is a pharmaceutical composition comprising this protein with a pharmaceutically acceptable carrier and optionally calcium ions.
Patent NZ-588080-A (NZ)
Title: 2-Aza-bicyclo[2.2.1]heptane derivatives
Inventor: AISSAOUI HAMED
IPC: A61K31/4709
Filed: 2009-02-19
Abstract: Disclosed is a 2-aza-bicyclo[2.2.1]heptane derivative of formula (I), or a salt thereof, where n is 0 or 1, A and B are each optionally substituted aryl or heterocycle, and the other substituents are as defined in the specification. Also disclosed is the use of the compound for treating selected all types of sleep disorders, stress related syndromes, psychoactive substance use and abuse, cognitive dysfunctions in the healthy population and in psychiatric and neurologic disorders, and eating or drinking disorders.
Patent NZ-588130-A (NZ)
Title: A heated electric towel rail with two electrical connectors
Inventor: SPRINGFIELD ANDREW
IPC: F26B3/00
Filed: 2009-04-03
Abstract: A heated electric ladder-type towel rail, comprises a frame 1 having interconnected conduits for accommodating a heating element 2, the conduits forming a ladder construction, one or more heating elements 2 located within the frame 1, a first electrical connector 3 for electrically connecting a heating element 2 to an electricity supply located at a first position with respect to the frame 1, and a second electrical connector 3' for electrically connecting a heating element 2 to an electricity supply located at a second position with respect to the frame 1, different to the first position. The heating elements 2 pass along a snaking path through the interconnected conduits from a first end of the heating element 2 to a second end of the heating element 2.
Patent NZ-588478-A (NZ)
Title: Ventilation circuit surrounding proximal aerosol delivery channel
Inventor: MAZELA JAN
IPC: A61M16/08
Filed: 2009-03-17
Abstract: 588478 An adaptor for delivering an aerosolized active agent to a patient with concomitant positive pressure ventilation includes an aerosol flow channel having an aerosol inlet port and a patient interface port, and defining an aerosol flow path from the aerosol inlet port to and through the patient interface port; and a ventilation gas flow channel in fluid communication with the aerosol flow channel and having a gas inlet port and a gas outlet port, and defining a ventilation gas flow path from the gas inlet port to and through the gas outlet port, wherein the ventilation gas flow path is at least partially offset from the aerosol flow path and at least partially encircles the aerosol flow path. Systems and methods for delivering an aerosolized active agent to a patient with concomitant positive pressure ventilation incorporate the adaptor.
Patent NZ-588519-A (NZ)
Title: Balanced solenoid valve
Inventor: NEFF ROBERT H
IPC: F15B13/02
Filed: 2009-06-12
Abstract: 588519 Disclosed is a solenoid operated valve assembly (10). The assembly includes a solenoid can (14) having an internal coil (22). A valve body (12) connected to the solenoid can includes an inlet port and a first valve seat. An axially adjustable retainer threadably connected to the valve body includes an end portion defining a second valve seat. A homogenous valve member/armature (18) slidably disposed in the valve body moves in the presence of a coil generated magnetic flux between valve closed and valve open positions. A valve member/armature first surface area is in fluid communication with a pressurized fluid through the inlet port (50). A valve member/armature second surface area is in fluid communication with the pressurized fluid in the valve closed position. The first surface area is equal to the second surface area and the pressurized fluid acts equally on the first and second surface areas defining a pressure balanced condition in the valve closed position.
Patent NZ-596024-A (NZ)
Title: Indole compounds
Inventor: TALLEY JOHN JEFFREY
IPC: C07D401/12
Filed: 2007-08-07
Abstract: 596024 Disclosed are indole derivatives of formula A that are useful for treating pain, inflammation and other conditions are described. Certain of the compounds are benzyl derivatives and others are benzoyl derivatives. The compounds are substituted at least at the 3 position of the indole. Examples of compounds of formula A are: 1-[(4-chlorophenyl)methyl]-N-(3-fluoro-4-pyridinyl)-5-methoxy-2-methyl-alpha-oxo-1H-Indole-3-acetamide 1-[(2,4-difluorophenyl)methyl]-N-(2-methoxy-4-pyridinyl)-2,5-dimethyl-alpha-oxo-1H-Indole-3-acetamide N-(2-chloro-4-pyridinyl)-5-methoxy-1-[(4-methoxyphenyl)methyl]-2-methyl-alpha-oxo-1H-Indole-3-acetamide N-(2-chloro-4-pyridinyl)-1-[(4-fluorophenyl)methyl]-5-methoxy-2-methyl-?-oxo-1H-Indole-3-acetamide
Patent NZ-596643-A (NZ)
Title: Fungicidal composition, comprising tolclofos-methyl
Inventor: TSUDA NAOKI
IPC: A01N57/10
Filed: 2010-05-25
Abstract: A fungicidal composition comprising tolclofos-methyl, polyoxyethylene polyarylphenol phosphate, polyoxylethylene polyoxypropylene block copolymer, polyoxyethylene fatty alcohol ether and water has good stability of the formulation at high temperature. The application can be carried out by spraying a liquid fungicidal composition of the present invention to seeds. Further, the fungicidal composition of the present invention may be used for soil application or foliar application. Examples of the plant diseases controlled by the present invention include diseases caused by phytopathogenic fungi (in particular of the classes of Ascomycetes, Deuteromycetes, Oomycetes and Basidiomycetes) such as Magnaporthe grisea, Cochliobo/us miyabeanus, Rhizoctonia so/ani and Gibberella fujikuroi on rice; Erysiphe graminis, Fusarium graminearum, F. avenacerum , F. cu/morum, Microdochium niva/e, Puccinia striiformis, P. graminis, P. recondita, P. hordei, Typhu/a sp., Micronectriella nivalis, Ustilago tritici and U. nuda.
Patent NZ-599710-A (NZ)
Title: Radiator or cooling device mounted as part of barrier around helicopter landing platform on top of nacelle
Inventor: MUNK-HANSEN THORKIL
IPC: F03D11/00
Filed: 2012-05-01
Abstract: 599710 A wind turbine 5 is provided with a helicopter landing platform 3 on the top of the nacelle 2. At least three sides of the platform are surrounded by a barrier 4, 6, 7, at least part of which forms a radiator or heat exchanger for a cooling system for the machinery of the turbine to remove heat from within the nacelle to the ambient air.
Patent NZ-602098-A (NZ)
Title: Noodle scraper having a plate body and first and second scraping tines having different lengths
Inventor: ISHII YUJI
IPC: A21C11/24
Filed: 2009-10-09
Abstract: 602098 Disclosed is a noodle scraper with a plate body having a bent section extending along a longitudinal direction and having a plurality of first scraping tines (22) having a longest tine-length and a plurality of second scraping tines (23) each having a tine-length which is shorter than that of the first scraping tines. The plurality of first scraping tines and the plurality of second scraping tines are alternately provided at one of long sides of the plate body in a comb form. The second scraping tines include a tine-base section (24) or a tine-middle section which is formed in a folded shape or a curved shape. A tine-edge section of the first scraping tine or a tine-edge section of the second scraping tine includes a sloped face (34a) that is sloped in a direction orthogonal to a direction in which the tine-edge section extends.
Patent NZ-603404-A (NZ)
Title: Antiseptic cap with thread cover
Inventor: ANDERSON WILLIAM
IPC: A61M5/00
Filed: 2008-06-23
Abstract: 603404 Disclosed is an antiseptic cap equipped plunger assembly for use with a central venous catheter to maintain sterility of the catheter. The assembly comprises a plunger rod having a first end and second end opposed to the first end, the first end having a housing with a first wall defining a first chamber; and an antiseptic or disinfectant cap positioned within the first chamber and having an access site contacting surface, the antiseptic cap having a second generally cylindrical side wall defining a second chamber, the second generally cylindrical side wall having an outer cylindrical surface, the second generally cylindrical side wall having an interior surface with a set of threads extending along a portion of the interior surface, the access site contacting surface having an antiseptic substance, the antiseptic cap having a plurality of circumferentially spaced ribs extending radially outward from and axially along an outermost peripheral surface of the antiseptic cap on the second generally cylindrical side wall. The access site contacting surface comprises a member having an absorbent sponge material containing a liquid antiseptic and the member is positioned within the chamber.
Patent NZ-612150-A (NZ)
Title: Collapsible saw stool
Inventor: SPAANS ALLAN
IPC: F16M11/24
Filed: 2012-05-14
Abstract: 612150 A collapsible saw horse stool which has an elongate deck, a base with coupling means, legs which are able to releasably engage with the coupling means and an elastic thread. The stool formed such that for a normal assembled disposition the legs can be engaged with the coupling means such that the thread inherently stretches to create tension to assist in maintaining engagement between the coupling means and the legs.
Patent NZ-619409-A (NZ)
Title: Antibody-based dual targeting molecules and methods for generating same
Inventor: BECKMANN ROLAND
IPC: C07K16/46
Filed: 2012-05-29
Abstract: Disclosed is an antibody or functional fragment thereof comprising at least one variable binding domain consisting of a heavy chain variable (VH) domain and a light chain variable (VL) domain, wherein said binding domain comprises two paratopes for two unrelated epitopes, wherein (i) binding of each paratope to its epitope does not prevent the simultaneous binding of the other paratope to its respective epitope, wherein (ii) both paratopes comprise at least one residue from at least one VH CDR and at least one residue from at least one VL CDR, and wherein (iii) the first paratope comprises residues from CDR1 and CDR3 of the VL domain and CDR2 of the VH domain, and the second paratope comprises residues from CDR1 and CDR3 of the VH domain and CDR2 of the VL domain.
Patent NZ-620218-A (NZ)
Title: Catalytic biomass conversion
Inventor: OLKOWSKI ANDREW A
IPC: D21C9/16
Filed: 2012-06-29
Abstract: Disclosed is a method of producing crystalline cellulose from cellulose, comprising the steps of (a) reacting the cellulose in an aqueous slurry having a pH less than 7, comprising a transition metal catalyst and hydrogen peroxide, until a crystalline cellulose fraction forms, and (b) recovering the crystalline cellulose fraction formed at (a).
Patent NZ-708091-A (NZ)
Title: Stabilized insulin-like growth factor polypeptides
Inventor: FORNARO MARA
IPC: C07K14/65
Filed: 2013-12-16
Abstract: This invention is in the field of Insulin-like growth factors 1 (IGF-1) modifications. It relates to modified IGF-1 polypeptides and modified IGF-1 precursor polypeptides wherein the cleavage of E-peptide is prevented. In particular, the present invention provides a polypeptide comprising a human IGF-1 protein variant having at least 90% identity to SEQ ID NO: 1, wherein the amino acid glycine at position 42 is mutated to serine. The invention also relates to the use of such polypeptides for treating muscle diseases and disorders.
Patent NZ-708824-A (NZ)
Title: Tetracycline topical formulations, preparation and uses thereof
Inventor: SALMAN MOHAMMAD
IPC: A61K9/10
Filed: 2013-11-08
Abstract: The invention relates to a topical suspension formulation that includes a tetracycline, a liquid medium and a polymeric gelling agent. The tetracycline may be in the form of its pharmaceutically acceptable salts, hydrates, or polymorphs and is in a suspended form within the formulation. The liquid medium is selected such that it does not dissolve or substantially minimally dissolves the tetracycline. The gelling agent is a polymeric hydrocarbon gelling agent. Preferably, the tetracycline has a particlesize of less than or equal to about 20microns.
Patent NZ-709902-A (NZ)
Title: Ornamental component with gripping element
Inventor: GRAY LEE ANTONY
IPC: A44C11/00
Filed: 2014-02-03
Abstract: A problem to be solved is to provide a robust ornamental component provided with a stopping mechanism that can be easily manufactured. Disclosed is an ornamental component for a bracelet and / or a necklace. The ornamental component having a through hole allowing the ornamental component to be strung on an elongated member of a bracelet and / or necklace, said through hole defining a through hole axis. The ornamental component comprising: a self-supporting housing having a through hole comprising a first opening at a first side of the self-supporting housing and a second opening at a second side of the self-supporting housing; and an insert assembly inserted in said through hole of said self-supporting housing. The insert assembly is assembled from a first tubular element having a through hole that forms at least a part of said through hole of said ornamental component and a gripping element for frictionally gripping a part of said bracelet and / or necklace. The first tubular element is configured to secure said gripping element inside said through hole of said ornamental component. The provision of the gripping element around the outside of the bead support insert with the gripping element protruding through the relatively hard support, allows for a more simple production and protection of the gripping element.
Patent NZ-711033-A (NZ)
Title: Nanofluidic devices for the rapid mapping of whole genomes and related systems and methods of analysis
Inventor: RAMSEY JOHN MICHAEL
IPC: G01N35/08
Filed: 2014-03-11
Abstract: Devices and methods generate an ordered restriction map of genomic DNA extracted from whole cells, nuclei, whole chromosomes, or other sources of long DNA molecules. The devices have a fluidic microchannel that merges into a reaction nanochannel that merges into a detection nanochannel at an interface where the nanochannel diameter decreases in size by between 50% to 99%. Intact molecules of DNA are transported to the reaction nanochannel and then fragmented in the reaction nanochannel using restriction endonuclease enzymes. The reaction nanochannel is sized and configured so that the fragments stay in an original order until they are injected into the detection nanochannel. Signal at one or more locations along the detection nanochannel is detected to map fragments in the order they occur along a long DNA molecule.
Patent NZ-728749-A (NZ)
Title: Anti-pd-l1 antibodies
Inventor: ZHA JIPING
IPC: C07K16/28
Filed: 2015-08-05
Abstract: The present disclosure relates to antibodies and antigen-binding fragments thereof that bind to PD-L1, and to methods of using such antibodies and antigen-binding fragments. For example, the present invention provides humanized anti-PD-L1 antibodies and methods of use thereof. In a particular embodiment, the PD-L1 antibody comprises the heavy chain CDRs: TYGVH, VIWRGVTTDYNAAFMS, and LGFYAMDY; and the light chain CDRs: KASQSVSNDVA, YAANRYT, and QQDYTSPYT.