baber/WOPTO huggingface dataset:
Patent IL-76121-A0 (IL)
Title: Protein absorption enhancing agents
IPC: A61K38/38
Filed: 1985-08-18
Abstract: The absorption rate of proteins with medicinal properties in the blood is enhanced by administering the protein intramuscularly together with an absorption enhancing agent, preferably hydroxylamine or a salt thereof, most preferably hydroxylamine hydrochloride.
Patent IL-97158-A0 (IL)
Title: Side-chain homologous vitamin d derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
IPC: C07C401/00
Filed: 1991-02-06
Abstract: The description relates to novel side-chain-homologous vitamin D derivatives of formula (I), in which R<1>, R<2>, R<3>, R<4>, R<5> and R<6> have the significance given in the description, B and D are either a hydrogen atom or together a second bond (E-configuration double bond) and either A is a direct bond between the carbon atoms 20 and 22 and X is an alkyloxy radical -(CH2)nO- with n = 1 to 3 or A is a methylene bridge (-CH2-) between the carbon atoms 20 and 22 and X is an alkylene radical -(CH2)n- or an alkylenoxy radical -(CH2)nO- with n = 1 to 3, or if A is a direct bond and B and D together are a second bond, (a) is one of the radicals (b) , -(CH2)2-= or -(CH2)2-=, and a process for their production, pharmaceutical preparations containing this compound and its use in making medicaments. The new compounds have proliferation-inhibiting and cell-differentiating effects.
Patent IL-98032-A0 (IL)
Title: Ceramic preforms,their production and products made therefrom
IPC: C04B35/80
Filed: 1991-05-02
Abstract: Preforms made of ceramics comprising  alpha  alumina single crystals in the form of hexagonal platelets. Among these preforms, the invention relates very particularly, on the one hand, to the preforms consisting essentially of hexagonal  alpha  alumina platelets and, on the other hand, to the mixed preforms in which the said platelets are associated with one or a number of other ceramic products, the  alpha alumina content preferably remaining predominant. The process for their manufacture comprises the use of amorphous, transition or hydrated alumina and of a fluorine-containing flux. These preforms can be employed as such or for the manufacture of composites.
Patent IL-98524-A0 (IL)
Title: Enantiomers of tetrahydrofuran derivatives,their preparation and pharmaceutical compositions containing them
IPC: A61P35/02
Filed: 1991-06-17
Abstract: The compound of formula I <CHEM> and its enantiomer with the (S) configuration can be prepared by appropriate substitution, protection and/or deprotection from the compound of formula II <CHEM> which itself can be prepared by enantiospecific monohydrolysis of 2,2-bis(hydroxymethyl)tetrahydrofuran dibutyrate. They have unusual pharmacological activity: the compound of formula I has activity in treating multiple sclerosis and its enantiomer in treating tumors. The compound of formula II and its protected forms are useful intermediates for preparing further optically pure pharmacologically active compounds having an asymmetrically substituted carbon atom adjacent to the oxygen atom in a tetrahydrofuran ring.
Patent AU-PS084202-A0 (AU)
Title: A lifting apparatus
IPC: B66F7/02
Filed: 2002-03-01
Abstract: A portable telescopic lifting apparatus ( 1 ) for lifting aerial cables ( 53 ). The apparatus ( 1 ) comprises a tubular housing ( 2 ), first and second telescopic members ( 3, 4 ) extendible from and retractable into the housing ( 2 ), a drive ( 5, 60 ) for extending and retracting the telescopic members ( 3, 4 ), and a cable-engaging member ( 51 ) attached to the second telescopic member ( 4 ) for lifting one or more aerial cables ( 53 ). The drive ( 5, 60 ) comprises a chain lever block ( 5 ) and a pulley arrangement ( 60 ). In use, the apparatus ( 1 ) is positioned below one or more aerial cables ( 53 ), the chain lever block ( 5 ) is used to raise the first telescopic member ( 3 ), the first telescopic member ( 3 ) extends from within the housing ( 2 ), the second telescopic member ( 4 ) extends from within the first telescopic member ( 3 ), and cable-engaging member ( 51 ) raises the cable/s ( 53 ).
Patent FI-20000515-A0 (FI)
Inventor: ITAELAE ARI
IPC: A61L27/00
Filed: 2000-03-07
Abstract: A method for etching the surface of a bioactive glass, in which the glass surface is contacted with an acid fluoride solution. The solution contains a complexing agent that forms a complex with ions dissolving from the bioactive glass.
Patent FI-20002399-A0 (FI)
Inventor: MIKKOLA HANNU
IPC: H03M13/27
Filed: 2000-10-31
Abstract: A method and arrangements are provided for transmitting frames of digital information over a wireless communication connection between a transmitter and a receiver. In the transmitter, a certain sequence of bits within each frame of digital information is convolutionally encoded and punctured before transmitting the frame over a wireless communication connection. The receiver decodes and depunctures the sequence of bits within each frame of digital information, that was convolutionally encoded and punctured, after receiving the frame over a wireless communication connection. The transmitter rearranges the sequence of bits within each frame of digital information that is to be convolutionally encoded and punctured, before convolutionally encoding and puncturing it. The rearranged order is one that has been found to produce, during the course of convolutionally encoding with a certain convolutional code and puncturing with a certain puncturing pattern, a convolutionally encoded and punctured sequence where the statistical probability of transmission errors exhibits a predefined behavior. In the receiver, the sequence of bits within each frame of digital information that was so rearranged in the transmitter is inversely rearranged so that the effect of said rearranging in the transmitter on the mutual order of the bits of the sequence is cancelled, after decoding and depuncturing the sequence of bits.
Patent IL-102824-A0 (IL)
Title: Sidewall actuator for a high density ink jet printhead
IPC: B41J2/015
Filed: 1992-08-16
Abstract: A sidewall actuated channel array for a high density ink jet printhead. The sidewall actuator (28) includes a top wall (16), a bottom wall (12) and at least one elongated liquid confining channel (18) defined by the top wall (16), the bottom wall (12) and sidewalls (30,32). The actuator sidewall is comprised of a first actuator sidewall section (32) formed of a piezoelectric material poled in a first direction perpendicular to a first channel (18) and attached to the top wall (16), a second actuator sidewall section (30) attached to the first sidewall section (32) and the bottom wall (12), and means for applying an electric field across the first actuator sidewall section (32) and perpendicular to the direction of polarization. When the electric field is applied across the first sidewall section (32), the actuator sidewall engages in a motion which produces an ink ejecting pressure pulse in the channel (18). <IMAGE>
Patent IL-107157-A0 (IL)
Title: Immunopotentiatory agents and pharmaceutical compositions comprising them
IPC: A61P37/04
Filed: 1993-09-29
Abstract: The present invention relates to the use of 4-(2-formyl-3-hydroxyphenoxymethyl) benzoic acid or physiologically acceptable salts thereof as an immunopotentiatory agent, compositions containing such a compound and their manufacture, combinations of such a compound with anti-tumour or anti-infective drugs and the use of such combinations in the prophylaxis or treatment of such diseases arising from tumours or infections.
Patent IL-113930-A0 (IL)
Title: A sheet-like carrier for active substances
IPC: A61K9/52
Filed: 1995-05-31
Abstract: A strip-shaped film substrate with openings and loaded with an active substance serves as the basis for the production of an active substance carrier for the controlled release of active substances in the gastro-intestinal tract with delayed passage through the pylorus.
Patent IL-115196-A0 (IL)
Title: Benzoylguanidines substituted by heterocyclic n-oxide process for their preparation their use as a medicament or diagnostic agent medicament containing them and intermediate products for their preparation
IPC: A61P9/10
Filed: 1995-09-06
Abstract: Benzoyl guanidine derivs. of formula (I) and their salts are new: one of R1-R3 = Het (linked by C or N), SR10, OR10, NR10R11 or CR10R11R12; and the other two of R1-R3 = H, halo, CN, X(CH2)p(CqF2q+1), SOuR22, CONR23R24, COR25, SO2NR26R27, 1-8C alkyl, 2-8C alkenyl, CmH2mR14, OR35 or NR35R36; R4, R5 = H, 1-4C alkyl, Fl, Cl, OR32, NR33R34 or CrF2r+1; R10 = CnH2n-Het; Het = 1-9C heteroaryl-N-oxide (opt. substd. by 1-3 F, Cl, CF3, OMe, OH, NH2, NHMe or NMe2); R11, R12 = as R10, H or 1-4C alkyl; R14 = 3-9C cycloalkyl or phenyl (opt. by 1-3 F, Cl, CF3, Me, OMe, NH2, NHMe or NMe2); R11, R12 = as R10, H or 1-4C alkyl; R14 = 3-8C cycloalkyl or phenyl (opt. substd. by 1-3 F, Cl, CF3, Me, OMe, NH2, NHMe or NMe2); X = a bond, O, S or NR28; R22 = 1-8C alkyl, 2-6C alkenyl, CmH2mR29 or CF3; R23, R25, R26 = H or as R22; R24, R27 = H or 1-4C alkyl; or R23 + R24, R26 + R27 = (CH2)4 or (CH2)5 (both opt. with a CH2 replaced by O, S, NH, NMe or N-benzyl); R28 = H or 1-3C alkyl; R29 = 3-7C cycloalkyl or phenyl (opt. mono- or tri-substd. by F, Cl, CF3, Me, OMe or NR30R31; R30, R31 = H or 1-4C alkyl; R35, R36 = H or 1-6C alkyl; or R35 + R36 = (CH2)y (opt with a CH2 replaced by O, S, NH, NMe or N-benzyl); R32-R34 = H or 1-3C alkyl; n, p, u = 0-2; m = 0-4; r = 1-4; q = 0-6; y = 4-7. Also claimed are cpds. of formula (IIIA); A = Cl, OR45, OH, OM or imidazol-1-yl; M = alkali or alkaline earth metal ion; and R45 = 1-8C alkyl or 1-4C alkylphenyl.
Patent IL-115270-A0 (IL)
Title: Methods of decontaminating soils containing hazardous substances
IPC: G21F9/30
Filed: 1995-09-12
Abstract: Soil including sand and clays contaminated with nuclear waste materials, elemental mercury or as mixed waste with hazardous organic compounds are decontaminated by treating with anhydrous liquid ammonia alone or with solvated electrons. Methods comprise concentrating radionuclides, such as plutonium and uranium in the fines of soil and clay to yield residual soil products which are sufficiently free of contaminants to allow reclamation. By concentrating nuclear wastes in soil fines space requirements ordinarily needed for storage of untreated soil and handling costs can be significantly reduced. Ammoniacal liquids, such as anhydrous liquid ammonia facilitates decontamination by breaking up soil into fine slurries for releasing droplets of mercury metal. The high density of the mercury permits precipitation with larger soil particles and for recovery from soil particulates.
Patent IL-115300-A0 (IL)
Title: Ú1, 2, 4¾Triazolo Ú4, 3-a¾ quinoxalinone derivatives their preparation and pharmaceutical compositions containing them
IPC: A61K31/4985
Filed: 1995-09-14
Abstract: PCT No. PCT/DK95/00364 Sec. 371 Date Mar. 7, 1997 Sec. 102(e) Date Mar. 7, 1997 PCT Filed Sep. 12, 1995 PCT Pub. No. WO96/08492 PCT Pub. Date Mar. 21, 1996The present invention relates to [1,2,4]triazolo[4,3-a]quinoxalinone compounds of the formula wherein R1 is POX'X'' or alkyl substituted with COX' or POX'X'', and X' and X'' independently are hydroxy or alkoxy, and R7 is trifluoromethyl, and R6, R8 and R9 independently are piperidino, piperazinyl, morpholino, or thiomorpholino, which rings are optionally substituted with one or more of phenyl or C1-6-alkyl and phenyl optionally being substituted with C1-6-alkoxy; and pharmaceutically acceptable salts thereof. The compounds of the present invention are useful in the treatment of indications caused by hyperactivity of the excitatory neurotransmitters.
Patent IL-118201-A0 (IL)
Title: Erythropoietin free of animal proteins processes for production and use thereof
IPC: C12N15/09
Filed: 1996-05-09
Abstract: New therapeutic compsn. contains a protein (I) with erythropoietin activity produced in a host cell and: (a) contg. \~ 100 ppm protein from the host cell; (b) contg. \~ 10 pg DNA from the host cell per 83 ~mg (I), and (c) being entirely free of natural mammalian protein not derived from the host cell.
Patent IL-130775-A0 (IL)
Title: Utilizing a convection cooled electronic circuit card for producing a conduction cooled electronic card module
IPC: H05K7/20
Filed: 1999-07-02
Abstract: A conduction cooled electronic card module is designed for insertion into a chassis of an electronic device so as to transfer thereto a heat generated by electronic components of the module. The module comprises a circuit card of a convection cooled type, and a thermally conductive frame carrying the circuit card. The circuit card has a front surface carrying at least a part of the electronic components, and a rear surface at least edge areas of which are adapted to be in thermal contact with the chassis. The frame is in thermal contact with the part of the electronic components and with the front surface of the circuit card at least at edge areas thereof, so as to conduct heat generated by the electronic components, via the edge areas of the front surface to the edge areas of the rear surface of the circuit card.
Patent IL-132503-A0 (IL)
Title: The use of alpha-methyl-p.tyrosine to inhibit melanin production in iris melanocytes
IPC: A61P27/02
Filed: 1998-04-21
Abstract: The use of agents for blocking the synthesis of tyrosinase to prevent permanent pigmentation of the iris caused by melanin deposit induced by pharmacological treatments or by metabolic imbalance is described.
Patent IL-132747-A0 (IL)
Title: Identification of objects by means of multiple imaging
IPC: G01N15/10
Filed: 1998-05-12
Abstract: Detection of fetal nucleated red blood cells (NRBCs) is achieved by employing a combination of brightfield and fluorescence images of nuclear and cytoplasmic markers. The brightfield and fluorescence images are all obtained with a single multi-bandpass dichroic mirror. The objects in the sample are stained with a fluorescent dye that selectively stains nuclei and a dye that selectively stains fetal hemoglobin in the cytoplasm of fetal RBCs. UV excitation provides fluorescent emissions from the stained cell nuclei and visible illumination provides brightfield transmission of light that is absorbed by the stained cytoplasm. The images are processed to determine regions where the fluorescent emissions by cell nuclei in response to the UV excitation and the absorption by fetal hemoglobin of the brightfield illumination overlap or are in close proximity. The brightfield and fluorescence images may be sequentially acquired or derived from a single image where the UV excitation and visible illumination occur simultaneously.
Patent IL-138586-A0 (IL)
Title: Epitopes in viral envelope proteins and specific antibodies directed against these epitopes and use for detection of hcv viral antigen in host tissue
IPC: C12P21/08
Filed: 1999-03-29
Abstract: Antibodies to two new epitopes on the HCV envelope proteins were identified which allow routine detection of native HCV envelope antigens, in tissue or cells derived from the host. The new epitopes are: the E1 region aa 307-326 and the N-terminal hyper variable region of E2 aa 395-415. Surprisingly, we characterized an antibody which reacts with various sequences of the hypervariabie domain of E2. Specific monoclonal antibodies directed against these epitopes and allowing routine detection of viral antigen are described.
Patent IL-139266-A0 (IL)
Title: A method and apparatus for producing inorganic fullerene-like nanoparticles
IPC: C01G39/06
Filed: 2000-10-25
Abstract: A process and apparatus are presented for obtaining inorganic fullerene-like nanostructures. A metal oxide is evaporated at predetermined temperature conditions, and is swept towards a reacting zone, to which first and second gas phase reacting agents are concurrently swept. The evaporated metal oxide thus interacts with the first reacting agent and is converted into metal suboxide nanoparticles in the gas phase. The condensing metal suboxide nanoparticles interact with the second reacting agent in the gas phase resulting in substantially pure phase of the inorganic fullerene-like nanoparticles.
Patent IL-140159-A0 (IL)
Title: Neuroprotective composition for the prevention and/or treatment of nervous and behavioral alterations due to anxiety states or depression
IPC: A61K31/35
Filed: 1999-06-17
Abstract: This invention relates to a composition of acetyl-L-carnitine in combination with hypericin and/or Hypericum extract (Hypericum perforatum L. (St. John's Wort)) in synergistically effective amounts. The composition is effective at treating a nervous alteration due to an anxiety state, irritability, or depression.
Patent IL-140438-A0 (IL)
Title: Polyketides and their synthesis
IPC: C12N15/09
Filed: 1999-06-29
Abstract: A polyketide synthase ("PKS") of Type I is a complex multienzyme including a loading domain linked to a multiplicity of extension domains. The first extension module receives an acyl starter unit from the loading domain and each extension module adds a further ketide unit which may undergo processing (e.g. reduction). We have found that the Ksq domain possessed by some PKS's has decarboxylating activity, e.g. generating (substituted) acyl from (substituted) malonyl. The CLF domain of type II PKS's has similar activity. By inserting loading modules including such domains into PKS's not normally possessing them it is possible to control the starter units used.
Patent IL-148087-A0 (IL)
Title: Adjustable damper for airflow systems
IPC: F24F3/16
Filed: 2001-01-29
Abstract: A damper for an air flow system opening, such as the air inlet of a clean room filter module, includes a number of control plates (14, 15) reciprocally mounted on holding elements (22) and a drive element (24, 36) supported from a supporting surface (20) with an airflow opening (21) therein. Gaskets (30, 31) seal around apertures (16, 18) and the airflow opening to allow more accurate and positive control and diffusion, as well as virtually complete shut off, of airflow through the opening. A tool (42) is used to rotate a threaded end (34) of the drive element rotatably held in an opening in a beam (40) by holders (38). The threaded end of the drive element cooperates with an internally threaded opening in a non-round-shaped traveler (36) passing through matching non-round openings in the control plates.
Patent IL-150201-A0 (IL)
Title: Novel piperidine and piperazine derivatives
IPC: C07D211/58
Filed: 2000-12-18
Abstract: The invention provides piperidine and piperazine derivatives of general formula (I), processes for their preparation, pharmaceutical compositions containing them, a process for preparing the pharmaceutical compositions, and their use in therapy
Patent IL-152995-A0 (IL)
Title: Transcutaneous prosthesis
IPC: A61F2/58
Filed: 2001-06-22
Abstract: A transcutaneous prosthesis which includes a first component shaped for implantation into a bone, a second component intended for location between the bone and the skin, the second component having a surface treatment for stimulation of fibroblastic cell proliferation and attachment of epithelial cells, and a third component intended for location exterior to the skin surface having a low surface energy which deters bacterial adhesion.
Patent IL-154964-A0 (IL)
Title: Benzsulfonamide derivatives, their preparation and pharmaceutical compositions containing them
IPC: A61P25/16
Filed: 2001-09-27
Abstract: The present invention is related to benzsulfonamide derivatives of formula I notably for use as pharmaceutically active compounds, as well as to pharmaceutical formulations containing such benzsulfonamide derivatives. Said benzsulfonamide derivatives are efficient modulators of the JNK pathway, they are in particular efficient and selective inhibitors of JNK 2 and 3. The present invention is furthermore related to novel benzsulfonamide derivatives as well as to methods of their preparation. <CHEM>   The compounds of formula I according to the present invention being suitable pharmaceutical agents are those wherein     Ar<1> is a substituted or unsubstituted aryl or heteroaryl group;   Ar<2> is a substituted or unsubstituted phenyl group;   X is O or S, preferably O; R<1> is hydrogen or a C1-C6-alkyl group, or R<1> forms a substituted or unsubstituted 5-6-membered saturated or unsaturated ring with Ar<1>; n is an integer from 0 to 5, preferably between 1-3 and most preferred 1; Y within formula I is an unsubstituted or a substituted 4-12-membered saturated cyclic or bicyclic alkyl containing at least one nitrogen atom, whereby one nitrogen atom within said ring is forming a bond with the sulfonyl group of formula I thus providing a benzsulfonamide.
Patent IL-155382-A0 (IL)
Title: Radioactive member and method of making
IPC: C07D213/85
Filed: 2001-11-01
Abstract: A radioactive member for use in brachytherapy comprising a molded elongate, bioabsorbable carrier material with spaced radioactive sources disposed therein, and methods for the manufacture thereof. The radioactive members may be used in the treatment of, for example, prostate cancer.
Patent IL-155476-A0 (IL)
Title: Methods and devices for dissolving hyperpolarised material for nmr analyses
IPC: G01R/
Filed: 2001-11-02
Abstract: The present invention relates to devices and method for melting solid polarised sample while retaining a high level of polarisation. In an embodiment of the present invention a sample is polarised in a sample-retaining cup (9) in a strong magnetic field in a polarising means (3a, 3b, 3c) in a cryostat (2) and then melted inside the cryostat (2) by melting means such as a laser (8) connected by an optical fibre (4) to the interior of the cryostat.
Patent IL-165121-A0 (IL)
Title: A process for the preparation of modafinil
IPC: C07C315/04
Filed: 2004-11-09
Abstract: A process for the preparation of 2-[(diphenylmethyl)sulfinyl]acetamide (I) comprising the oxidation of sodium 2-[(diphenylmethyl)sulfenyl]acetate to the corresponding sulfoxide and the derivatization of the latter to amide
Patent IL-165535-A0 (IL)
Title: Broad spectrum optically addressed sensor
IPC: G01N21/47
Filed: 2004-12-02
Abstract: The present invention relates to a sensor for detecting chemical, biological, biochemical or other environmental stimuli, and includes a plurality of colloidal particles having chemical receptors bound to each particle's surface, wherein when a target stimulus is directed to the bound chemical receptor, the gelled matrix contracts or expands, which changes the lattice constant, thereby changing the pattern of diffracted light in a measurable manner so that the target stimulus' presence can be detected by a spectrometer. The plurality of colloidal particles are composed of a material having a first dielectric constant, and the gel and surrounding medium have a second dielectric constant. The colloidal particles can be assembled using holographic optical tweezers and polymerized to create an integrated sensor array, which diffracts light in a detectable characteristic manner.
Patent IL-165743-A0 (IL)
Title: Composite webs produced by a continuous solid state web coating process
IPC: B05D5/06
Filed: 2004-12-13
Abstract: One or more particulate active agents are fused to the surface of a substrate web by mixing the particulate agents with a particulate binder having a particle size not exceeding an average diameter of approximately 40 microns and coating the composite mixture onto the surface of the substrate. Thereafter; the coated substrate is heated to a temperature equal to or greater than the Vicat softening temperature of the binder and compressed within the nip of a pair of pressure rolls to achieve fusion. If desired, a top layer may be placed upon the coated composite prior to the compression step. Also disclosed are various products manufactured by the process.
Patent IL-174668-A0 (IL)
Title: Device and method for making particles
IPC: B01F15/02
Filed: 2006-03-30
Abstract: Device for continuously producing particles, consisting of a homogenising compartment ( 1 ) including at least one inlet ( 2 ) for feeding in an organic phase, an inlet ( 3 ) for feeding in an aqueous phase, a mixing system ( 4 ) and an outlet ( 5 ).