Patent SG-11201804090P-A (SG)
Title: Use of 1,3 diglyceride in a topical composition for countering the weakening of the skin barrier
Inventor: REDOULES DANIEL
IPC: A61Q19/00
Filed: 2016-12-08
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property -' Organization International Bureau rest0) (43) International Publication Date ..... ..sr.1 15 June 2017(15.06.2017) WIPO I PCT (10) WO International 111111111111311111111111111111111111111111111111111111111111111111111311111111111111111 2017/097919 Publication Al Number (51) International Patent Classification: AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, A61K 8/37 (2006.01) A61Q 19/00 (2006.01) BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, A61Q 17/00 (2006.01) A61K 8/06 (2006.01) DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, (21) International Application Number: KP, KR, KW, KZ, LA, LC, LK, LR, LS LU, LY MA, PCT/EP2016/080295 MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, (22) International Filing Date: NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, 8 December 2016 (08.12.2016) RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, (25) Filing Language: English ZA, ZM, ZW. (26) Publication Language: English (84) Designated States (unless otherwise indicated, for every (30) Priority Data: kind of regional protection available): ARIPO (BW, GH, 1561994 8 December 2015 (08.12.2015) FR GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, (71) Applicant: PIERRE FABRE DERMO-COSMETIQUE TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, [FR/FR]; 45, place Abel Gance, 92100 Boulogne-Billan- DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, court (FR). LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, (72) Inventors: REDOULES, Daniel; 18, rue du Dr Bernard- beig, 31100 Toulouse (FR). JOSSE, Gwendal; 14, me des GW, KM, ML, MR, NE, SN, TD, TG). Fleurs, 31000 Toulouse (FR). Declarations under Rule 4.17: (74) Agent: REGIMBEAU; 20, me de Chazelles, 75847 Paris — of inventorship (Rule 4.17(iv)) Cedex 17 (FR). Published: Designated (81) States (unless otherwise indicated, for every with international search report (Art 21(3)) kind AE, AG, AL, AM, of national protection available): (54) Title: USE OF 1,3 DIGLYCERIDE IN A TOPICAL COMPOSITION FOR COUNTERING THE WEAKENING OF THE SKIN BARRIER Il .4t Ct I'l Ct Ir -- - Ri 2K 0 01 0 N 1-1 C (57) : This invention relates ei general formula (I), in which the radicals and at least one cosmetic or deiinatological 0 to a topical, cosmetic R1 and R2 represent, independently of one another, a C13 to C40 saturated and linear alkyl excipient 0 0 R2 OH (I) or dermatological composition, comprising a 1,3 diglyceride having the for a topical application on the skin This invention also relates to such 0 radical, a composition, or a 1,3 diglyceride having the formula (I), for its use in protecting the skin, in countering the weakening of the skin barrier and in preventing or reducing the penetration of exogenous molecules into the skin following a weakening of the skin barrier.