baber/WOPTO huggingface dataset:
Patent PH-17143-A (PH)
Title: 1-phenyl-2-aminoethanol derivatives
Inventor: JONES GERAINT
IPC: H01J29/07
Filed: 1980-05-12
Abstract: The invention concerns compounds of the formula:- R1.CH(OH).CH2NH.CR2R3.A1. NH.CO.CHR4.A2.NR5. Q I wherein R1 is 3,4-bis[(3-8C)alkanoyloxy]-phenyl, 3,5- bis [(3-8C)alkanoyloxy]phenyl, 3-[(3-8C)alkanoyloxy]methyl-4-[(3-8C)alkanoyloxy]phenyl, 4-[(3-8C)alkanoyloxy]phenyl, 2-chlorophenyl or 3,5-dichloro-4-aminophenyl; R2 and R3 are independently hydrogen or (1-4C) alkyl; A1 is (1-4C) alklylene; A2 is a direct bond or (1-4C) alkylene; R4 is hydrogen, (1-6C)alkyl, phenyl-(1-4C)alkyl or halogenophenyl-(1-4 C)alkyl; and R5 is (1-6C)alkyl; or R4 and R5 together form (2-5C) alkylene; and Q is (3-12C) alkanoyl, [(3-6C)alkoxy]carbonyl, phenylacetyl, phenoxyacetyl, benzoyl or benzyloxycarbonyl, the phenyl rings of which may optionally bear a substitutent selected from halogeno, (1-4C)alkyl, (1-4C)alkoxy and trifuloromethyl; and the pharmaceutically acceptable acid-addition salts thereof; processes for their manufacture; and pharmaceutical compositions thereof. The compounds of formula I are topical anti-inflammatory agents. A representative compound is 1-[3,4-bis (pivaloyloxy)phenyl]-2-{2-[(N-phenylacetyl-proyly)amino]-1,1-dimethyl- ethylamino}ethanol.
Patent PH-21078-A (PH)
Title: 3-azinomethyl rifamycins
Inventor: LEONARDO MARSILI
IPC: C07D519/00
Filed: 1985-03-03
Abstract: There are provided 3-azinomethyl rifamycins of the for- mulal:whereinR represents hydrogen or acetyl;R<sub>1</sub> represents hydrogen or lower alkyl;R<sub>2</sub> represents an alkyl group having from 2 to 4 carbon atoms substituted by a dialkoxy group each having from 1 to 3 carbon atoms;R<sub>3</sub> represents an alkyl group having from 1 to 4 carbon atoms;R<sub>2</sub> and R<sub>3</sub> may form with the amino nitrogen atom a 4- to 8- membered heterocyclic ring, having a maximum of two hetero atoms, substituted by hydroxy-, alkoxy-, dialkoxy- or alkylenedioxy groups each having from 1 to 4 carbon atoms, arylalkoxyimino groups having from 7 to 9 carbon atoms, acyloxy groups having from 1 to 4 carbon atoms;R<sub>1</sub> and R<sub>2</sub> may form with the amino nitrogen atom and the carbon atom a 5 to 7-membered heterocyclic ring optionally substituted by alkyl or alkoxy group having from 1 to 4 carbon atoms.The compounds display antibacteria activity against Gram-positive and Gram-negative bacteria and Mycobacteria.Process for the preparation of the above compounds and their pharmaceutical compositions are also described and claimed.
Patent PH-24129-A (PH)
Title: New pyridine compounds with basic substituents,medicaments containing them and their use
Inventor: ELBEN ULRICH
IPC: C07D213/80
Filed: 1986-11-21
Abstract: A pyridine compound of the formula I    <IMAGE>  (I)  in which R1 and R2 independently of each other represent hydrogen or alkyl having from 1 to 4 carbon atoms, R3 represents hydrogen or alkyl having up to 2 carbon atoms and A represents alkylene having 2 to 4 carbon atoms, n is O or 1, Z is a group of the formula Za, Zb or Zc <IMAGE>  in which either R4 is hydrogen and R5 is phenyl or cinnamyl or R4, R5, R7 and R8 independently of each other are pyridyl, phenyl or phenyl which is substituted by up to 2 equal or different substituents from the group halogen and alkoxy having up to 2 carbon atoms, R6 is hydrogen or hydroxy and X is hydrogen, a cyano, amino or nitro group or the group -CO-R9, in whcih R9 is hydroxy or alkoxy having from 1 to 4 carbon atoms, and the physiologically tolerable salts of these compounds. The invention also relates to a process for the manufacture of such compounds and to their use in pharmaceutical compositions.
Patent PH-31675-A (PH)
Title: Lipophilic oligosaccharide antibiotic salt compositions.
Inventor: MANESH PATEL
IPC: A61K31/00
Filed: 1992-10-14
Abstract: Pharmaceutically acceptable compositions of matter comprising a lipophilic oligosaccharide antibiotic, e.g., the everninomicin-type antibiotic of Formula III, at least a stoichiometric amount of a base, e.g., NMG, an amount of, e.g., hydroxypropyl-b-cyclodextrin, and optionally a pharmaceutically acceptable non-ionic surfactant, e.g., Tween-80, pharmaceutical compositions containing such compositions of matter, methods of treating and preventing susceptible bacterial infections in animals especially human beings as well as a method of preventing adverse reaction syndrome while simultaneously delivering an antiinfective amount of a lipophilic oligosaccharide antibiotic such as that of Formula III to said animals as well as the use of the compositions of matter for the preparation of a medicament for such treating or preventing are disclosed. <CHEM>
Patent TR-25033-A (TR)
IPC: E04G9/02
Filed: 1991-06-17
Abstract: A frame (3) of a form panel (1) is formed by a hollow profile (4), preferably having a closed cross-section, the cross-section of this hollow profile (4) corresponding substantially approximately to a rectangle. Provided adjacent to the outermost edge web (5) of this hollow profile (4) but without affecting the length or width of this edge web (5), on a profile section or end web (9) running transversely to this edge web (5), is at least one recess (7), to which a crowbar (8) can be attached when the edge web (5) is standing on a ground surface (6) or the like. The edge web (5) can thus have its greatest possible width on the hollow profile (4) despite such a recess (7) serving for the engagement of a crowbar (8) and is protected in the best possible way against deformations by the crowbar (8), so that it remains a substantially level and undeformed stop for a neighbouring shuttering element even after prolonged use. 
<IMAGE>
Patent TR-27992-A (TR)
IPC: A61K8/00
Filed: 1994-08-18
Abstract: The present invention relates to water or alcohol soluble or dispersible silicone grafted thermoplastic elastomeric copolymers and to cosmetic and pharmaceutical compositions containing these copolymers. This invention especially relates to copolymers useful for hair styling purposes, and to hair styling compositions containing these copolymers. This invention further relates to copolymers useful for providing cosmetic and pharmaceutical compositions for topical application to the skin. These topical skin care compositions are useful for delivering and/or transdermally transporting active ingredients to or through the skin.
Patent UY-34825-A (UY)
Inventor: IBRAHIM PRABHA N
IPC: A61K31/435
Filed: 2013-05-24
Abstract: SCAN FORMULA 1 DE REIV 1
Patent UY-36586-A (UY)
Title: Heterociclilmetiltienouracilos y uso de los mismos
Inventor: KALTHOF DR BERND
IPC: C07D249/08
Filed: 2016-03-14
Abstract: La presente solicitud se refiere a derivados novedosos de tieno[2,3-d]pirimidina-2,4-diona ("tienouracilo") que presentan un tipo particular de sustituyente (azaheterociclil)metilo, a procesos para la preparación de los mismos, al uso de los mismos por sí solos o en combinaciones para tratar y/o prevenir enfermedades y al uso de los mismos para producir medicamentos para tratar y/o prevenir enfermedades, especialmente para tratar y/o prevenir trastornos pulmonares y cardiovasculares y cáncer.
Patent YU-16794-A (YU)
Title: Ski trenažer
Inventor: MIROSLAV ILIC
Filed: 1994-04-05
Abstract: SKI TRENAŽER prema MKP ima oznaku A 63B 69/18. Pritiskom na skiju 10, donji kraj poluge 11 se pomera u nazad i zateže sajlu 16 oko remenice 17 čime se bočno pomeraju nosači skija 3 i 3A rotirajući oko klinova 2 i 2A pri čemu se skija 10 zadnjim krajem spušta i istovremeno rotira oko klina 2 ka regulatoru sajle 19 a skija 10A se zadnjim krajem podiže i istovremeno rotira oko klina 2A u istom smeru. Pritiskom na skiju 10A kretanje skija 10 i 10A je inverzno predhodnom u smeru ka regulatoru sajle 19A.
Patent YU-25593-A (YU)
Inventor: MACOR J E
IPC: A61K31/40
Filed: 1993-04-09
Abstract: PCT No. PCT/US93/01807 Sec. 371 Date Sep. 14, 1994 Sec. 102(e) Date Sep. 14, 1994 PCT Filed Mar. 4, 1993 PCT Pub. No. WO93/21180 PCT Pub. Date Oct. 25, 1993.    <IMAGE>  (I)  Compounds of formula (I) where n is 0, 1, or 2; m is 0 or 1; Y and W are each an amino acid residue; R1 is hydrogen, C1-C6 alkyl, C3-C6 alkenyl, C3-C6 alkynyl, aryl, C1-C3 alkylaryl, or C1-C3 alkylheteroaryl, and -(CH2)pR3; R2 is CF3, C1-C6 alkyl, aryl, C1-C3 alkylaryl, and -OR5; R3 is cyano, trifluoromethyl, or -OR4; R4 is hydrogen, C1-C6 alkyl, C1-C3 alkylaryl, or aryl; R5 is C1-C6 alkyl, C1-C3 alkylaryl, or aryl; R6 is hydrogen, -OR7, or -NHCOR7; R7 is hydrogen, C1 to C6 alkyl, aryl or C1 to C3 alkyl-aryl; p is 1, 2, or 3; and the above aryl groups and the aryl moieties of the above alkyl-aryl groups are independently selected from phenyl and substituted phenyl, wherein said substituted phenyl may be substituted with one to three groups selected from C1 to C4 alkyl, halogen, hydroxy, cyano, carboxamide, nitro, and C1 to C4 alkoxy and the pharmaceutically acceptable salts thereof. These compounds are useful in treating migraine and other disorders. These compound are useful psychotherapeutics and are potent serotonin (5-HT1) agonists and may be used in the treatment of depression, anxiety, eating disorders, obesity, drug abuse, cluster headache, migraine, pain, and chronic paroxysmal hemicrania and headache associated with vascular disorders, and other disorders arising from deficient serotonergic neurotransmission. The compounds can also be used as centrally acting antihypertensives and vasodilators.
Patent YU-30499-A (YU)
Title: Endothelin intermediaetes by asymmetric conjugate addition reaction using a chiral additive
Inventor: TILLYER RICHARD D
IPC: C07D263/06
Filed: 1998-01-09
Abstract: This invention relates to a process for the preparation of a key intermediate in the synthesis of an endothelin antagonist, having formula (I) by using a chiral additive to effect an asymmetric conjugate addition.
Patent YU-30994-A (YU)
Title: Pištolj poluautomatski većega dometa
Inventor: PANIC B
Filed: 1994-05-26
Abstract: Predmet pronalaska je pištolj poluautomatski većega dometa. Pronalazak pripada oblasti tehnike, ubojnih mehaničkih naprava u naoružanju vojske SR Jugoslavije, za padobranske jedinice, za akrije u pozadini protivnika, izvođenje akcija u naseljenim mestima, diverzijama i sličnim akcijama. Sastavljen je od rukohvata (3), na kojem je zatvarač (2) sa udarnom iglom (6), udarnom oprugom (7) i vođicom (8), nišanskim elementima (10 i 4), šaržerom (21), obaračom (17) za oslobađanje udarne igle (6). Povratna opruga (26) vraća zatvarač (2) u prednji položaj i zabravljuje sa cevi (1) u položajima (Z). Pištolj poluautomatski je skladnih dimenzija, može da se nosi skriven ispod garderobe, velikoga je dometa i ubojne moći. Može da se usadi na futrolu, kao parabelum za oslonac kao kundak.
Patent YU-97492-A (YU)
Title: Novi derivati lupana i postupak za njihovo dobijanje
Inventor: BOUBOUTOU R
IPC: A61K31/56
Filed: 1992-11-12
Abstract: novi derivati lupana opšte formule (I): u kojoj R označava: u kojoj su R' i R" identični ili različiti i označavaju H ili alkil, X je veza, karbamoil ili aminokarbonil koji su u datom slučaju supstituisani, Y je veza ili fenilen, RВ° i RВ°В° su identični ili različiti i označavaju H ili alkil ili RВ° označava OH, hidroksialkil, fenil, benzil, karbamoilmetil, ili zajedno sa azotom iz X, kada X označava kar-bomoil, formira heterociklus i Y je veza, i n, m i p su celi brojevi od 0 do 16, pri čemu je 4 m+n+p 16, R1 je metil, R2 je hidroksi, metil, hidroksimetil, -CH2OR'2, -CH2SR'2 ili -CH2NHR'2 ili R2 označava supstituisan amino ili dialkilamino čiji alkil delovi mogu formirati heterociklus, R3 je H ili zajedno sa R1 ili R2 formira metilen ili okso, R4 i R5 su različiti i označavaju H ili hidroksi, ili zajedno formiraju okso, hidroksiimino ili alkiloksiimino koji može biti supstituisan, a R6 i R7 su H, ili R4 i R5, R6 i R7, zajedno formiraju radikale okso, pri čemu su radikali alkil (1 do 4 C-atoma) neračvasti ili račvasti, kao i njihove soli kada ove postoje i njihovo dobivanje. Ovi novi produkti prema pronalasku su naročito značajni u oblasti SIDE.
Patent BE-813080-A (BE)
Title: Heavy metal and bromine recovery from residues - obtained from liquid phase oxidation of alkylbenzenes using heavy metal and bromine as oxidation catalyst
Inventor: SHIGEYASU M
IPC: B01J37/30
Filed: 1974-03-29
Abstract: Very pure heavy metals and bromine are recovered from a mother liquor obtd. by separating terephthalic acid from arriving at the casting hole. The casting hole is surrounded by an annular channel-shaped hollow whose bottom is below the level of the upper edge of the casting hole, and an annular wall projects downwardly into the hollow without touching the bottom of the hollow at all points.
Patent BE-820711-A (BE)
Title: Cartridges of gelled aq. explosive mixt. made in situ - using synthetic polymeric gelling agent, packed in unsealed case of flexible film
IPC: C06B47/14
Filed: 1974-10-04
Abstract: Cartridges are made by prepg. a friable gelled explosive in situ, using a synthetic polymeric gelling agent and contg. >=50 wt% of a water-soluble inorg. oxygen-releasing salt, and subsequently packing the explosive into an unsealed container made from a flexible, non-elastic sheet. The friable gels are partic. suited to processing by standard equipment, e.g. as used for nitroglycerine, into paper cartridges. Suitable gelling agents comprise copolymers, or terpolymers of unsatd. monomers e.g. acrylamide or vinylpyrrolidone, vinyl alcohol, methacrylic acid, dimethylaminoethylmethacrylate, etc., and contg. a radical which is capable of reacting with metallic ions, esp. to form a chelate, e.g. beta-ketoacyloxy, omicron-hydroxybenzoyl, silicylate, alpha,beta-dihydroxyl etc.
Patent BE-898742-A (BE)
Title: Boiler for central heating - circulates water round fire box in spiral pattern at speed increasing with rising temperature
IPC: F24H1/43
Filed: 1984-01-24
Abstract: The central-heating boiler circulates the water round the firebox in a spiral path at a speed of 0.5 metres per second, this being increased as temperature rises. - The water then follows a second spiral path in contact with the gases in the flue.
Patent BE-900124-A (BE)
Title: Procede et dispositif pour la formation de piles d'articles plats et flexibles, en particulier des imprimes.
IPC: B65H31/26
Filed: 1984-07-10
Abstract: Pour former une pile couchée (4) les imprimés (9) sont successivement mis en place chaque fois sur le dernier imprimé (9'). A cette fin est prévu un transporteur (12) avec au moins une chaine circulante (13) à laquelle sont fixés à intervalles réguliers des doigts d'entrainement (17) qui saisissent le bord arrière (9b) des imprimés (9). Plusieurs galets presseurs (39) sont fixés à un disque porteur (37) qui est entrainé en synchronisme avec la chaine transporteuse de façon à tourner dans le sens des aiguilles  d'une montre (D). Un galet presseur (39') appuie chaque fois sur le dernier imprimé (9') de la pile (4), en se trouvant juste devant le bord avant (9a) de l'imprimé suivant (9''), et se déplace avec cet imprimé dans le sens de mise en place (C) de celui-ci vers le haut.
Patent BE-779427-A (BE)
Title: Compressed tablets of special shape - to facilitate packing
IPC: A61J3/10
Filed: 1972-02-16
Abstract: Tablets are packed in discontinuous pockets formed at certain distances from each other between two continuous strips of packing material; the individual pockets are formed by hot welding. In the new packing the tablets are essentially rectangular in shape and so made that they can be received into a pocket which is smaller than that required hitherto for a normal rectangular tablet. The tablet consists of a small platelet obtd. by the compression of a suitable compsn. with a punch in a die of corresponding shape; the two opposite principal faces have a convex form which is partly spherical. Each of the principal faces is delimited by four curved edges connected by rounded corners. The lateral faces have an ellipsoidal form. In the packed assembly, the dimensions of each pocket in the packing material, such as paper, sheet aluminium or regenerated cellulose, are only slightly larger than the tablets because of the convexity of their principal faces; no shapr edges exist which might pierce the walls of the pocket.
Patent CA-1045803-A (CA)
Inventor: TOKUGAWA YOSHIHARU
IPC: C08L75/04
Filed: 1974-05-16
Granted: 1979-01-09
Abstract: ABSTRACT OF THE DISCLOSURE This invention relates to a process for producing a liquid product of a toluene diisocyanate tar occurring as a by-product in the preparation of toluene diisocyanate.  The process comprises dissolving or dispersing the tar in a specific aromatic solvent.  The liquid product produced by the process may be used as a curing agent in the production of an inexpensive urethane compositions.
Patent CA-1038849-A (CA)
Inventor: GAAF JAN
IPC: C10G59/02
Filed: 1974-09-27
Granted: 1978-09-19
Abstract: A B S T R A C T The invention relates to a new crystalline aluminosilicate zeolite having a specific X-ray powder diffraction pattern and the following composition expressed in moles of the oxides: 0.7-1.3 Na2O.Al2O3. 3.5-7.5 SiO2. 0.01-2 MOn/2.0-12 H2O, where M is a metal of Group VIII of the Periodic System of Elements having the valency n.     After dehydration of the zeolite at 10-6  Torr and 400°C and measured at a hydrocarbon pressure of 100 Torr and a temperature of 100°C, the adsorption of n-hexane is at least 500 µmoles/g and the ratio of the number of µmoles/g n-hexane adsorbed to the number of µmoles/g 2,3-dimethylbutane adsorbed is at least 8. The invention also relates to a process for preparing the new zeolite by keeping an aqueous mixture having the following composition expressed in moles of the oxides 2-10 Na2O.Al2O3. 8-20 SiO2. 0.01-2.5 MOn/2. 100-450 H2O, at a temperature between 70 and 160°C.     The new zeolite is suitable as molecular sieve, catalyst and catalyst carrier for the separation and the conversion of hydrocarbons, particularly shape-selective hydrocracking of normal paraffins in mixtures with other hydrocarbons.
Patent CA-1042505-A (CA)
Inventor: LENHART JAMES H F
IPC: H02J4/00
Filed: 1974-11-22
Granted: 1978-11-14
Abstract: ABSTRACT An electrical demand limiting system is disclosed in which a DC signal proportional to the total power demand averaged for a given interval of time is compared with a plurality of preselected demand limits.  Each demand limit is a percentage of the total permissible power demand.  A plurality of loads are sequentially switched from each of the demand set points over a predetermined time period.
Patent CA-1044437-A (CA)
Inventor: HANSEN ROLF S
IPC: C01B25/22
Filed: 1975-03-18
Granted: 1978-12-19
Abstract: Process for Manufacturing of Phosphoric Acid Abstract of the Disclosure The invention relates to a process for the production of phosphoric acid containing calcium phosphates, i.e. Ca-containing mother liquor from the Odda process, whereby practically all the remaining nitrate and fluorine are removed in the form of HNO3, HF and SiF4, in which process the Ca-containing mother liquor is given a Ca/P weight ratio which is lower than 0.45 and is evaporated while recycling Ca-containing phosphoric acid, the recirculation being so controlled that the liquor has a phosphorus concentration during evaporation which is always adequate to prevent the liquor from forming a paste-like mass.  Thus, it was discovered that the undesirable paste-like consistency experienced when calcium is present during evaporation can be avoided by controlling the phosphorus content.  More particularly, it was found for most types of rock phosphate that the phosphorus concentration should be below about 15% by weight or above about 22% by weight in order to avoid the formation of a paste-like mass during evaporation of the liquor.
Patent CA-1048645-A (CA)
Inventor: CHU WILLIAM M
IPC: G11C29/04
Filed: 1975-04-17
Granted: 1979-02-13
Abstract: TEST TECHNIQUE FOR SEMICONDUCTOR MEMORY ARRAY           Abstract of the Disclosure Disclosed is a technique for testing electronic storage arrays including bistable storage cells fabricated in accordance with integrated semiconductor technology.  Also described is the testing of load devices in a flip flop storage cell which is connected to a pair of bit lines that are inaccessible for the direct application of test signals. Testing is performed by altering the time duration of signals applied to the memory cells under test.
Patent CA-1059464-A (CA)
Inventor: JAKIMOWICZ CHRISTOPHER C
IPC: C10B33/00
Filed: 1975-05-28
Granted: 1979-07-31
Abstract: POLLUTANT COLLECTION SYSTEM FOR  COKE OVEN DISCHARGE OPERATION                   Abstract of the Disclosure A pollution collection and exhaust system is provided in a battery of coke ovens for removal of atmospheric pollutants from the gases released at the time of discharge of coke from an oven.  A coke guide carriage is provided with an exhaust hood which encloses the coke guide and extends over the transfer car thereby enxhrouding the discharging coke and resulting fumes and smoke during the discharge operation.  The exhaust hood is movable along the length of the oven battery.  A stationary exhaust mani-fold extends along the battery in spaced relation above the oven exhaust hood.  The exhaust hood is equipped with connecting means which are adapted to register in coplanar sealing engagement with selected gated openings in the manifold while simultaneously opening these gates.  Pollutants are exhausted from the discharge site and conducted through the manifold and associated treating apparatus with draft induced by an exhaust means connected to the manifold and treating apparatus.
Patent CA-1040534-A (CA)
Inventor: MCGINITY JAMES W
IPC: A61K31/58
Filed: 1975-05-28
Granted: 1978-10-17
Abstract: ABSTRACT      This invention describes a stabilized steroid composition comprising from 0.01% to 0.5% by weight of the steroid 9.alpha.-fluoro-21-chloro-11.beta.,16.alpha.,17.alpha.-trihydroxypregn-4-ene-3,20-dione, 16,17-acetonide, 0.005 to 0.2% by weight of an antioxidant selected from the group consisting of propyl gallate, butylated hydroxy-toluene, butylated hydroxyanisole, sodium bisulfite, sodium metabi-sulfite, and ascorbic acid, and polyethylene glycol or a poly-ethylene glycol ester, said polyethylene glycol or polyethylene glycol ester having a polyethylene glycol molecular weight of from 200 to 7500 and, optionally, including an oleaginous material.  This composition is useful in the treatment of various dermatoses.
Patent CA-1061574-A (CA)
Inventor: RITCEY GORDON M
IPC: C01G39/00
Filed: 1975-07-29
Granted: 1979-09-04
Abstract: SOLVENT EXTRACTION RECOVERY OF METALS             USING QUINOLINE DERIVATIVE     Abstract of the Disclosure A novel procedure is described for stepwise, selective extraction of metal values selected from molybdenum, copper, cobalt and zinc, using a substituted 8-hydroxyquino-line as solvent extraction reagent.  By controlling the equilibrium pH and other extraction conditions, it is possible to stepwise, selectively extract molybdenum and copper from aqueous, acidic solutions containing these along with other metal values.  Where cobalt and/or zinc are also present, these can also be stepwise selectively extracted using the same reagent.  It was previously believed that the substituted 8-hydroxyquinolines were selective only for copper over a wide pH range.