baber/WOPTO huggingface dataset:
Patent CA-2407377-A1 (CA)
Inventor: ZONDLO NEAL JOSEPH
IPC: C12N15/62
Filed: 2001-04-24
Abstract: La présente invention se rapporte à un échafaudage protéique, tel qu'un polypeptide pancréatique, qui peut être modifié par substitution d'au moins deux restes d'acides aminés qui sont exposés sur le domaine d'hélice alpha du polypeptide lorsque ce dernier se présente sous une forme tertiaire.
Patent CA-2407644-A1 (CA)
Inventor: DESMARTEAU DARRYL D
IPC: C07C309/87
Filed: 2000-09-18
Abstract: The present invention provides a monomer having the formula A-B, wherein A i s represented by Formula I:wherein B is selected from -OCF=CF2 and -A; wherein , when B is -OCF=CF2, the orientation of B is meta or para to the trifluorovinyloxy group of A; wherein, when B is A, the bond joining the A groups is para to the trifluorovinyloxy group of each A; and wherein each Z is independently selected from -SO2F, -SO2Cl, -SO3H, -SO2-N(M)-SO2CF3, and -SO2 - N(M)-SO2Rf ; wherein M is any suitable cation and Rf is a C1 to C10 fluorocarbon or fluorinated ether group. The present invention also provides  a monomer according to Formula II:wherein X is F, Cl, or N(M)SO2Rf; wherein M is any suitable cation and Rf is a C1 to C10 fluorocarbon or fluorinated ether group.
Patent CA-2408766-A1 (CA)
Title: Content delivery network bypass system
Inventor: WANG MEA
IPC: H04L1/00
Filed: 2002-10-17
Abstract: The bypass network is designed to provide fast access and high quality streaming media services anywhere anytime. There are five major components including Peering Gateway, Content Locator, Edge Server, Gateway and Client. The whole bypass network is divided into number of self-managed sub-networks, which are referred as local networks in this document. Each local network contains Edge Servers, gateways, and a Content Locator. The Edge Servers serve as cache storage and streaming servers for the local network. The gateways provide a connection point for the client computers. Each local network is managed by a Content Locator. The Content Locator handles all client requests by communicating with the Peering Gateway and actual web sites, and makes the content available on local Edge Servers. The Content Locator also balances the load on each Edge Server by monitoring the workload on them. One embodiment is designed for home users whose home machine does not move around frequently. A second embodiment is designed for business users who travel around very often where the laptops would self-configure as a client of the network.
Patent CA-2410721-A1 (CA)
Title: Ultra-thin plate electrochemical cell and method of manufacture
Inventor: JUERGENS TRISTAN E
IPC: H01M50/559
Filed: 1990-06-14
Abstract: Electrochemical cells are made by coating the major faces of positive and negative plates with a layer of electro-chemically active paste, but leaving uncoated portions corresponding to single horizontal edge of the plates. A cell unit consisting of a positive plate, a negative plate and a sheet of separator disposed between said plates, is assembled in such a manner that the horizontal edge of the positive plate is aligned opposite the uncoated horizontal edge of the negative plate. Negative and positive connectors are attached to the horizontal edges of the cells in a circular motion.        The horizontal edge of the negative plate extends beyond the edge of the separator and the separator extends beyond the edge of the positive plate. The horizontal edge of the positive plate extends beyond the edge of the separator and the separator extends beyond the edge of the negative plate. The cell unit is assembled by spirally winding a single sheet of the separator and the negative and positive plates on a mandrel.
Patent CA-2412235-A1 (CA)
Inventor: SNYDER BRIAN
IPC: F02N15/00
Filed: 2000-06-12
Abstract: A security system (1) for selectively enabling and disabling the internal combustion engine of a vehicle is provided. The security system (1) includes a security module (3) which selectively interrupts current to or from crucial vehicle subsystems which are necessary for engine ignition or engine operation. The security module (3) attaches and locks to the electrical terminal (2) of a vehicle subsystem so that the security module (3) cannot be removed from the engine compartment of a vehicle without removing the entire vehicle subsystem. Moreover, the security module (3) covers and isolates the electrical terminal (2) of the vehicle subsystem so as to electrically isolate the electrical terminal (2) from unauthorized access. The security system (1) further includes a controller (29) and a switch element (31) which are located within the security module (3) for selectively controlling the flow of current from a conductive path to or from the vehicle subsystem which is sought to be controllably enabled and disabled.
Patent CA-2412787-A1 (CA)
Inventor: BOARDMAN KAY ALISON
IPC: C07K5/08
Filed: 2001-07-18
Abstract: A process for the preparation of a salt of 5-phenylpentanoyl-(S)-arginyl-(S) - alanyl-{(S)-2-[(R)-3-amino-2-oxopyrrolidin-1-yl]propionyl}-(S)-alanyl-(S)- arginyl-(S)-alanyl-4-aminophenylacetamide (SEQ ID NO: 1) which comprises deprotection of a compound of the formula II or a salt thereof: wherein Pg a nd R1 are defined in the description. Also claimed are intermediates used in th e process and the processes for the preparation of the intermediates.
Patent CA-2414719-A1 (CA)
Title: Curable resin compositions and process for preparing oligomers containing acrylate groups and substituted methacrylate groups
Inventor: LACHOWICZ ARTUR
IPC: C08F22/10
Filed: 2002-12-18
Abstract: A curable resin composition which exhibits excellent hardness of their curing products as well as storage stability is provided, and a simple method to obtain acrylated resins is provided. The composition comprises a curable oligomer which has an acryloyl group and a substituted methacrylate group represented by the following structure (see above formula) The process comprises a reaction step of reacting at least one monomeric multifunctional acrylate in the presence of a tertiary organic phosphine.
Patent CA-2416064-A1 (CA)
Title: Glucose-1-phosphate thymidylyltransferase and method for selecting inhibitors thereof
Inventor: BLANKENFELDT WULF
IPC: C12N9/12
Filed: 2001-07-13
Abstract: There is provided a method of obtaining selecting agents which inhibit the enzyme glucose-1-phosphate thymidylyltransferase (Rm1A) based upon analysis of a model of the active and regulatory site (s) of Rm1A and interaction therewith by a potential inhibitory agent. The invention is based upon the provision of information on the structure of Rm1A obtained through X-ray diffraction studies since a crystallised form of Rm1A was obtained for the first time. The purified and crystallised from of Rm1A, obtained fromPsemdomononas aeruginosa is also described.
Patent CA-2416706-A1 (CA)
Inventor: FURUKAWA KIYOSHI
IPC: A61K31/522
Filed: 2001-07-24
Abstract: The present invention is directed to medicines for the treatment or prevention of dementia comprising 2-aryl-8--oxodihydropurine derivatives of the formula (I):   (see formula I) wherein W is H, C1-6 alkyl, halogen, C1-6 alkoxy, or the like; X is H, C1-6 alkyl, a group of the formula (Q):--CH(R3)CON(R1)(R2) (wherein R1 is a C1-6 alkyl or the like; R2 is phenyl-substituted C1-4 alkyl or the like; and R3 is H or the like); Y is H, C1-6 alkyl, a group of the above formula (Q), or the like; and A is substituted phenyl or the like, with the proviso that one of X and Y is a group of the formula (Q) and the other is a group selected from those defined for X or Y except the groups (Q), or pharmaceutically acceptable acid addition salts thereof.  The above compounds exhibit an extremely potent ameliorating effect on learning disorders and/or dymnesia and thus are useful in the treatment or prevention of Alzheimer-type dementia, cerebrovascular dementia, senile dementia, etc.
Patent CA-2419831-A1 (CA)
Title: Methods for governing bone growth
Inventor: CALHOUN CHRISTOPHER J
IPC: A61B17/70
Filed: 2003-02-25
Abstract: Resorbable polymer barrier membranes and methods of their applications are disclosed In a broad embodiment, methods of governing bone growth, or preventing bone growth into a certain spatial area, includes the step of forming a spatial barrier with the present resorbable barrier membrane. The barrier membrane separates a bone-growth area and a non-bone-growth area, and prevents bone from growing into the non-growth area.
Patent CA-2420543-A1 (CA)
Inventor: CHALLITA-EID PIA M
IPC: C12Q1/68
Filed: 2001-08-22
Abstract: L'invention concerne un nouveau gène (désigné sous le nom de 158P1D7) et sa protéine codée. Alors que le 158P1D7 présente une expression spécifique de tissu dans un tissu d'adulte normal, il s'exprime de manière aberrante dans de multiples cancers comprenant ceux indiqués dans le tableau numéro 1. En conséquence, le 158P1D7 fournit une cible diagnostique et/ou thérapeutique pour des cancers. Le gène 158P1D7 ou un fragment de celui-ci ou sa protéine codée ou encore un fragment de celle-ci peuvent servir à choisir une réponse immunologique.
Patent CA-2421193-A1 (CA)
Title: Hiv peptides, antigens, vaccine compositions,immunoassay kit and a method of detecting antibodies induced by hiv
Inventor: SORENSEN BIRGER
IPC: G01N33/569
Filed: 2001-09-03
Abstract: The present invention comprises novel and modified peptides capable of inducing a HIV-1 specific immune response without antagonizing the cytotoxic  T- cell activity in order to achieve an effective prophylactic and therapeutic vaccine against HIV. The peptides are based on conserved regions of HIV gag p17 and p24 proteins. Antigens in free- or carrier-bound form comprising at least one of the said peptides, vaccine compositions containing at least one  of the antigens, immunoassay kits and a method of detecting antibodies induc ed by HIV or HIV specific peptides using such antigens, are described.
Patent CA-2422372-A1 (CA)
Title: Latex with surface properties modified by addition of a water soluble copolymer with amphiphilic character
Inventor: CASTAING JEAN-CHRISTOPHE
IPC: C08L53/00
Filed: 2001-09-11
Abstract: The invention concerns a latex with modified surface properties obtainable by a method which consists in adding a water soluble amphiphilic copolymer in an aqueous dispersion of a water-insoluble polymer obtained from ethylenically unsaturated monomers.
Patent CA-2422899-A1 (CA)
Inventor: KIMBER MATTHEW S
IPC: C07K1/00
Filed: 2001-09-27
Abstract: The disclosure includes description of the operation of data analysis techniques upon protein related information.
Patent CA-2425397-A1 (CA)
Inventor: BOUTTE VINCENT
IPC: H01B13/16
Filed: 2003-04-16
Abstract: The assembly (100) with a varnish applicator (1) to shroud a conductor wire has a kiln (2), with a chamber (4) as a passage for the wire (3) to pass through to be coated with a varnish. A heating system acts on the wire in the chamber, between the entry (5) and the exit (6), to evaporate the varnish solvents and bake the deposited varnish. The chamber atmosphere is low in oxygen, with an air feed (11) through an oxygen monitor (10). The chamber fan (13) and the air feed are spaced apart at the chamber, with the fan located between the solvent evaporation zone (B) and the air feed, to carry evaporated solvents towards the air feed to be consumed by combustion outside the varnish baking zone (A).
Patent CA-2427488-A1 (CA)
Inventor: BROWN ROBERT
IPC: G01N1/00
Filed: 2003-05-08
Abstract: The device allows molecular specimens to be isolated from the gel by the use of an electrophoresis system. The system consists of an electrode containing cap and a gel extractor which is made up of a sample collecting chamber and gel holding chamber with a cutting edge. The cutting edge is used to excise the desired band containing the desired molecular species from a polymer gel. Upon addition of the electrode containing cap to the gel extractor, the molecular species is isolated into the sample collecting chamber via electrophoresis by application of a potential across the gel layer. This forces the molecular specimen out of the gel and into a buffer solution in the sample collecting chamber. The buffer is extracted from the container with the molecular specimen as a ready-to-use reagent for other experiments.
Patent CA-2429469-A1 (CA)
Title: Genes humains de l'elongase, leurs utilisations et composes destines a leur modulation
Inventor: HAARDT MARTIN
IPC: A61P25/32
Filed: 2001-11-29
Abstract: La présente invention concerne des gènes de l'élongase, leurs polypeptides et leurs régions de contrôle, ainsi que l'utilisation de ces gènes, polypeptides et régions de contrôle pour identifier des compositions destinées à être utilisées dans le traitement de pathologies. Les compositions identifiées permettent de réguler l'expression des gènes de l'élongase ou de moduler l'activité de leurs produits protéinés. Les séquences nucléotidiques et d'acides aminés sont ELG4, ELG6 et ELG7. Les séquences et fonction de contrôle sont ELG1, ELG2, ELG3, ELG4, ELG5, ELG6 et ELG7.
Patent CA-2431192-A1 (CA)
Inventor: WU ARTHUR
IPC: B25B13/46
Filed: 2003-06-12
Abstract: A reversible ratchet wrench comprises a handle having a head portion at an end thereof. The head portion has a through hole, a first chamber and a second chamber. An engaging member is received in the through hole of the handle for free rotating. A pawl is received in the first chamber detachably meshed the engaging member. A switching device comprises an axle member and a turning member at an end of the axle member, and a driving device is made from a flexible wire to form a spiral coupling portion and a curved spring arm projected from an end of the coupling portion. The coupling portion is received in the second chamber and the spring arm is projected out to rest against the pawl at the driven portion thereof. The axle member of the switching member is inserted into the second chamber via the open end of the second chamber for driving the spring arm to turn, and then the pawl is driven to shift by the spring arm of the driving device.
Patent CA-2432012-A1 (CA)
Inventor: DEBEAR DONALD
IPC: H01L21/321
Filed: 2002-01-22
Abstract: L'invention concerne un composant électronique comprenant une couche (110) de substrat, une couche (120) diélectrique couplée à la couche (110) de substrat, un couche (130) d'arrêt couplée avec la couche (120) diélectrique, une couche (140) conductrice couplée avec la couche d'arrêt et une couche (150) protectrice couplée avec la couche (140) conductrice. L'invention concerne également un procédé permettant de produire un composant électronique. Ce procédé comprend les étapes suivantes : on introduit une couche (150) protectrice dans la couche (140) conductrice ou on assemble une couche protectrice à la couche à la couche (140) conductrice, on disperse cette couche (150) protectrice dans la couche (140) conductrice, on fait durcir la couche (150) protectrice, on introduit une solution de gravure dans la couche (140) conductrice et on grave la surface conductrice jusqu'à la rendre sensiblement plane.
Patent CA-2432915-A1 (CA)
Inventor: SAMPATH LESTER A
IPC: A61L17/00
Filed: 2001-12-21
Abstract: L'invention concerne des dispositifs médicaux que l'on traite avec une solution renfermant au moins un solvant et une combinaison de base libre de chlorhexidine et d'un sel de chlorhexidine hydrosoluble dans un rapport en poids se situant entre environ 1:1 et environ 1:5, de préférence environ 1:1.
Patent CA-2433629-A1 (CA)
Inventor: HALL DANNY JR
IPC: F25B41/04
Filed: 2003-06-26
Abstract: A five element refrigeration system whereby heating and cooling functions of the system can be accomplished as in a reverse cycle system without needing to reverse the flow of the liquid through the system. The system comprises a refrigerant compressor, a pair of air side heat exchangers, an air blower to provide circulation for the air side heat exchangers, a pair of water side heat exchangers, and a reservoir to provide cooling water for the water side heat exchangers. The refrigerant compressor increases the pressure of a refrigerant flowing through it, causing it to circulate through the first air side heat exchanger, or a reheat coil. The refrigerant continues to the first water side heat exchanger, which acts as a condenser. In a cooling mode, the refrigerant continues to the second air side heat exchanger, which acts as an evaporator. In a heating mode, the refrigerant continues to the second water side heat exchanger, which acts as an evaporator. The reservoir water leaving the first water side exchanger is preheated when entering the second water side exchanger. The increase in the water temperature increases the efficiency of the system. Various valves are employed so that any or all of the heat exchangers may be bypassed in the operation of the system.
Patent CA-2434809-A1 (CA)
Inventor: TAKUBO NOBORU
IPC: F23C9/08
Filed: 2003-07-09
Abstract: Combustion method and apparatus for NO x reduction which are capable of achieving NO x reduction with the value of exhaust NO x under 10 ppm, as well as CO reduction at the same time. The combustion method for fulfilling NO x reduction and CO reduction by suppressing temperature of combustion gas derived from a burner comprises a NO x reduction step for suppressing combustion gas temperature in such a manner that suppression of NO x generation is preferred to reduction of exhaust CO value, thereby keeping NO x value not more than a specified value, and a CO reduction step for thereafter reducing exhaust CO value resulting from the NO x reduction step to not more than a specified value.
Patent CA-2435101-A1 (CA)
Title: Systems and methods for land-use development, planning and management
Inventor: DE LICHANA DANIEL
IPC: G06Q50/26
Filed: 2003-07-14
Abstract: In systems and methods for land-use development, planning and management, the creation of an organized environment evolving in time and space is disclosed.  The system and method is sustained by a smart infrastructure centrally or de-centrally managed to link, in a given perimeter, on developed or undeveloped sites, private and/or public equipments and deliver services to customers that generate a quality of life based on qualified and quantified parameters. The systems and methods use a definition of services and an open architecture, flexible and scalable to integrate social, economic and technology changes. In one embodiment, a framework is used to propose or offer services.
Patent CA-2437933-A1 (CA)
Inventor: LIPTON STEVEN JAY
IPC: G06F17/30
Filed: 2002-03-06
Abstract: A web browser predictively and automatically searches for web documents linked to a currently displayed web page which contain terms of interest to a web browser user. Linked documents containing terms of interest are automatically retrieved and stored while the user views the current document such that if the user selects the link to stored document, it will be displayed without waiting for it to download. To further assist the user in finding the documents containing the user's interest terms, links in the current page leading to the documents of interest are highlighted, and special fast links to those pages may be created and displayed for even greater noticeability and usability by the user
Patent CA-2440384-A1 (CA)
Title: Refrigerating device
Inventor: TAKEGAMI MASAAKI
IPC: F25B1/10
Filed: 2003-01-23
Abstract: A refrigerating apparatus including three compressors (2A, 2B, 2C) and application side heat exchangers (41) (45, 51) for two channels is formed so that a first compressor (2A) is used only for the application side heat exchangers (45, 51) in a first channel of a circuit, a third compressor (2C) is used only for the application side heat exchanger (41) in a second channel of the circuit, and a second compressor (2B) is used in a switchable manner between the application side heat exchangers (45, 51) in the first channel of the circuit and the application side heat exchanger (41) in the second channel of the circuit.  Thus, not only the pipe arrangement at suction side is simplified, but also operation control is streamlined.
Patent CA-2442593-A1 (CA)
Title: Coating for medical devices comprising a copolymer of a polyalkylene gylcol terephthalate and an aromatic polyester
Inventor: SOHIER JEROME
IPC: A61F2/06
Filed: 2002-04-02
Abstract: The invention relates to a coating for medical devices. The coating comprises a specific copolymer of a polyalkylere glycol terephtalate and an aromatic polysester which the composition may be adjusted such as to archieve an excellent adhesion to a wide range of surfaces. The coating may further comprise an additive, such as a biologically active agent, which may be released in vivo in a controlled manner, as the degradability of the coating may also be adjusted to a predetermined rate. The invention further relates to a process for applying the coating to a surface and to a medical device comprising the coating.
Patent CA-2443370-A1 (CA)
Inventor: ORLICKY STEPHEN
IPC: C40B30/04
Filed: 2003-10-17
Abstract: The present invention relates to binding pockets of Skpl-Cdc53/Cullin-F-box protein (SCF) E3 ubiquitin ligases associated with substrate selection and/or orientation. In particular, the invention relates to a crystal comprising such binding pockets. The crystal may be useful for modeling and/or synthesizing mimetics of a binding pocket or ligands that associate with the binding pocket. Such mimetics or ligands may be capable of acting as modulators of the interactions of a SGF E3 ubiquitin ligase and its substrates, and they may be useful for treating, inhibiting, or preventing diseases modulated by such interactions. Methods are also provided for regulating a SCF E3 ubiquitin ligase comprising changing a binding pocket associated with substrate selection and/or orientation.
Patent CA-2443584-A1 (CA)
Title: Feeder tube for bulk product
Inventor: FORSBERG GOERAN
IPC: B65G65/46
Filed: 2002-05-07
Abstract: This invention relates to a feeder tube for bulk product, which comprises a cylindrical drum or tube (2) in which there are accommodated a large number of inlet openings (8) distributed along the length of the tube, a screw conveyer (3) disposed coaxially within the tube (2), a first arrangement for rotating the tube about its axis, a second arrangement for rotating the screw conveyer (3) relative to the tube (2), a third arrangement for moving the feeder tube (1) in the lateral direction, and activators (9A, 9B) for the bulk product, which activators form projections on the outer side of the tube (2) and are disposed on the tube in association with said inlet openings (8), wherein each cross section along at least 40 % of the length of the tube (2), preferably at least 70 %, more preferred at least 90 %, there are disposed at least two inlet openings (8) wherein that at least two actively positioned activators (9A, 9B) are also positioned in each cross section and that for a feeder tube (1) having a desired average volumetric capacity (V') the slot width (d) of the majority of the openings (8) is chosen by means of V'.sim.dn, wherein n is between 2-3, in combination with that in a portion comprising at least 30 % of the length of the tube (2) the total sum of the width (.SIGMA. d) of all openings (8) in each cross-section is between 150 - 700 mm.
Patent CA-2445095-A1 (CA)
Title: Method for genotyping microsatellite dna markers
Inventor: BELOUCHI ABDELMAJID
IPC: C12Q1/68
Filed: 2002-04-19
Abstract: The present invention provides a high throughput method for genotyping microsatellite markers. The technology uses a combination of oligonucleotides in a selective ligation reaction that discriminates mono-, di-, tri,- tetra-, penta-, hexa-, hepta-, octa- and nona-nucleotide repeated alleles in amplified DNA from individuals.