baber/WOPTO huggingface dataset:
Patent WO-2021113371-A1 (WO)
Title: Medical instrument guidance systems and methods
Inventor: STEM JESSICA N
IPC: A61B90/00
Filed: 2020-12-02
Abstract: A guidance system for performing a percutaneous access incision comprises an access needle comprising a shaft and a tip located at a distal end of the shaft, and a guidance pad comprising a dermal side, an outward side, an opening to receive the access needle, the opening extending between the dermal side and the outward side, and a feedback device viewable from the outward side to provide an indication of a depth of the tip beneath the guidance pad and a trajectory of the shaft from the opening. A method for planning guidance of an access needle into a patient in preparation for a minimally invasive surgical procedure comprises determining a location for an access point on the patient, positioning a guidance pad over the access point, inserting a tip of the access needle through the pad, and displaying guidance information on the guidance pad.
Patent WO-2022132203-A1 (WO)
Inventor: TIEMAN DAVID
IPC: A23F5/02
Filed: 2021-12-15
Abstract: Some implementations of the described methods relate to a process for frying coffee beans (and/or another food product) in a fry medium (such as cooking oil) and then centrifuging the coffee beans (and/or other food product) to remove a significant portion of the try medium. Although the frying and centrifugation can occur in separate devices, in some cases, the described systems comprise a device that acts as both a fryer and a centrifuge. Indeed, in some cases, after the coffee beans (or other food product) has been fry roasted in a perforated container (e.g., a basket), the fry medium is drained from the container, and container is spun. In some cases, liquid nitrogen is also applied to the beans (or other food product), before and/or after being fry7 roasted. Other implementations are described.
Patent WO-2021158398-A1 (WO)
Title: Proppant particulates formed from fluid coke and methods related thereto
Inventor: GORDON PETER A
IPC: C09K8/80
Filed: 2021-01-27
Abstract: Proppant particulates like sand are commonly used in hydraulic fracturing operations to maintain one or more fractures in an opened state following the release of hydraulic pressure. Fracturing fluids and methods of hydraulic fracturing may also use proppant particulates composed of fluid coke material (also referred to as fluid coke proppant particulates). In some instances, the fluid coke proppant particulates are characterized by a bulk density of less than about 0.9 grams per cubic centimeter.
Patent WO-2021173294-A1 (WO)
Inventor: FAGAN JAMES
IPC: A61B17/29
Filed: 2021-01-28
Abstract: An ultrasonic surgical instrument includes a transducer configured to produce a first mode of ultrasonic energy and a waveguide coupled to the transducer. The waveguide includes a proximal body portion coupled to and extending distally from the transducer. The proximal body portion is configured to receive the first mode of ultrasonic energy from the transducer for transmission therealong. The waveguide further includes a distal body portion, a blade extending distally from the distal body portion, and an articulation portion interconnecting the proximal and distal body portions. The articulation portion is configured to enable articulation of the distal body portion relative to the proximal body portion, to receive the first mode of ultrasonic energy from the proximal body portion, convert the first mode of ultrasonic energy into a second mode of ultrasonic energy, and transmit the second mode of ultrasonic energy along the distal body portion to the blade.
Patent WO-2021155248-A1 (WO)
Title: Bioresorbable implant with inside-out resorption for enhanced bone ingrowth and tissue integration and method of manufacturing thereof
Inventor: MANAVITEHRANI IMAN
IPC: A61L29/14
Filed: 2021-01-29
Abstract: Disclosed is a bioresorbable implant with enhanced bone ingrowth and tissue integration utilizing an inside-out resorption mechanism and a method to manufacture a bioresorbable implants for use in osteotomies and bone-soft tissue reconstruction surgeries. The bioresorbable implant includes a polymer A (e.g., an aliphatic polymer matrix) and/or poly(propylene fumarate)), a carbohydrate B (e.g., a bioresorbable natural carbohydrate filler) and a ceramic C. The implant may be a porous scaffold structures with suitable porosity, pore size, pore interconnectivity, and mechanical properties for enhanced osteoblast penetration and bone formation to fabricate tissue integrating bioresorbable implants. The implant may be shaped as wedges, bone void fillers, and soft tissue fixation implant like screws, rods and/or anchors. In some embodiments, the implant may be a putty.
Patent WO-2021158775-A1 (WO)
Title: Determining a value indicative of a thermoregulatory activty of a patient using a temperature management system
Inventor: WALLS GEORGE L
IPC: A61F7/00
Filed: 2021-02-04
Abstract: A temperature management system controls a temperature of a body of a patient and determines a value indicative of a thermoregulatory activity of the patient. The system includes a heat exchange system configured to exchange heat with a body of a patient and to record operational data while controlling the temperature of the body of the patient. The temperature management system receives temperature data from a sensor, controls the heat exchange system to maintain the temperature of the body of the patient within a target temperature range, receives, in response to the controlling, operational data, determines, based on the temperature data and the operational data, a value indicative of a thermoregulatory activity of the patient, and generates, based on the value, an alert through the user interface indicating the thermoregulatory activity of the patient.
Patent WO-2021159074-A1 (WO)
Title: Graphene-based sensor for detecting hemoglobin in a biological sample
Inventor: NAWANA NAMAL
IPC: G01N27/327
Filed: 2021-02-08
Abstract: In one aspect, a sensor for detecting hemoglobin protein (e.g., human hemoglobin protein) in a sample is disclosed, which includes a graphene layer, a plurality of binding agents coupled to said graphene layer to generate a functionalized graphene layer, where the binding agents exhibit specific binding to a hemoglobin protein (e.g., to human hemoglobin protein) and a plurality of electrical conductors electrically coupled to said functionalized graphene layer for measuring an electrical property (e.g., DC electrical resistance) of said functionalized graphene layer. While in some embodiments such binding agents are monoclonal antibodies, in other embodiments they can be polyclonal antibodies.
Patent WO-2021163429-A1 (WO)
Inventor: NIDO PATRICK
IPC: A61P17/00
Filed: 2021-02-12
Abstract: L'invention concerne la production et l'utilisation de compositions de matrice extracellulaire ou de milieu conditionné et plus spécifiquement des compositions obtenues par culture de cellules dans des conditions hypoxiques sur une surface dans un milieu de croissance approprié.
Patent WO-2021173992-A1 (WO)
Inventor: ZUNIGA BRANDON
IPC: G09G5/00
Filed: 2021-02-26
Abstract: A system and method for adding at least one label to at least one image. The system can comprise a computer and a user interface comprising an image display and at least one input device configured to permit a user to communicate with the computer. The system is configured to perform a method for adding a label to an image comprising at least one element. In a second aspect, the method comprises several steps including: displaying an image to a user on an image display of a user interface; receiving a positional indication from the user identifying a selected location on the image; and adding a label to the image at a location corresponding to the positional indication. The label comprises a symbolic designation identifying an element of the image, the symbolic designation generated by a system comprising the user interface and without the user fully specifying the symbolic designation.
Patent WO-2021183791-A1 (WO)
Title: Wnt/cbp/catenin signaling pathway inhibitors and uses thereof
Inventor: KAHN MICHAEL
IPC: A61P37/00
Filed: 2021-03-11
Abstract: Disclosed herein are, inter alia, compounds modulating activity and methods of use thereof for treating CBP/β-catenin mediated disorders.
Patent WO-2021188740-A1 (WO)
Inventor: ST GERMAIN BRYAN
IPC: C12N7/01
Filed: 2021-03-17
Abstract: La présente invention concerne des compositions et des procédés pour la production de virus adéno-associés recombinants (rAAV).
Patent WO-2021202772-A1 (WO)
Title: Multilamellar rna nanoparticle vaccine against sars-cov-2
Inventor: SAYOUR ELIAS
IPC: A61P31/14
Filed: 2021-03-31
Abstract: The present disclosure provides a nanoparticle comprising a positively-charged surface and an interior comprising (i) a core and (ii) at least two nucleic acid layers, wherein each nucleic acid layer is positioned between a cationic lipid bilayer, wherein the nanoparticle comprises RNA molecules encoding a SARS-CoV-2 protein. Methods of making such nanoparticles are further provided herein. Additionally, related cells, populations of cells, pharmaceutical compositions comprising the presently disclosed nanoparticles are provided. Methods of increasing an immune response against a tumor in a subject, methods of delivering RNA molecules to an intra-tumoral microenvironment, lymph node, and/or a reticuloendothelial organ in a subject, and methods of treating a subject with a disease are furthermore provided.
Patent WO-2021207462-A1 (WO)
Title: Allocating resources for implementing a well-planning process
Inventor: TAWIL AUS A
IPC: G06N5/00
Filed: 2021-04-08
Abstract: Methods and systems, including computer programs encoded on a computer storage medium can be used for an integrated methodology that can be used by a computing system to automate processes for generating, and updating (e.g., in real-time), subsurface reservoir models. The methodology and automated approaches employ technologies relating to machine learning and artificial intelligence (Al) to process seismic data and information relating to seismic facies. The geological model is used to determine resource requirements for implementing a well-planning process and to generate a field development plan.
Patent WO-2021212036-A1 (WO)
Title: Methods and apparatus to facilitate a multiple bit new data indicator
Inventor: RYU JUNG HO
IPC: H04L1/18
Filed: 2021-04-16
Abstract: Apparatus, methods, and computer-readable media for facilitating a multiple bit new data indicator are disclosed herein. An example method for wireless communication at a first device includes transmitting a first state of a multiple bit new data indicator (NDI) for a first packet. The example multiple bit NDI indicates more than two different states for indicating a new packet. The example method also includes transmitting the first packet. Additionally, the example method includes transmitting a second state of the multiple bit NDI for a second packet, and the second state being different than the first state. Further, the example method includes transmitting the second packet.
Patent WO-2021221989-A1 (WO)
Inventor: ROUNDS STEPHEN
IPC: G01C21/16
Filed: 2021-04-22
Abstract: A navigation apparatus determines an estimated position of an object. Navigation information that includes a sequence of quantized measurements is received. Each quantized measurement has a corresponding quantization error that is negatively correlated with the quantization error of a prior quantized measurement. The apparatus iteratively performs a navigation update operation that includes determining a state and a covariance matrix of the object for a current iteration based on a state and covariance matrix in a prior iteration. The state includes an end quantization error and a start quantization error. The covariance matrix includes end and start covariance values corresponding to the end and start quantization errors, respectively. Determining the state and the covariance matrix for the current iteration includes replacing the start quantization error with the end quantization error determined in a prior iteration, and updating the state and the covariance matrix via a Kalman filter update operation.
Patent WO-2021237130-A1 (WO)
Title: A system and method for teaching a robot to mimic precise human motions for creation of coffee and beverages
Inventor: SHUO LIU
IPC: G05B15/00
Filed: 2021-05-21
Abstract: A method for recording human motion performing a task with a tool and training a robot to perform the task, including the steps of performing tracker calibration without the robot present, performing teaching tool calibration with the robot present and placed at a predetermined location, and performing training without the robot present.
Patent WO-2021242829-A1 (WO)
Title: Powered opening module for a door closer
Inventor: LANGENBERG DANIEL
IPC: E05F5/02
Filed: 2021-05-26
Abstract: A retrofit module configured for use with a door closer having a pinion. The retrofit module generally includes a case, an output shaft, a motor, and a control assembly. The output shaft is rotatably mounted in the case, and is configured for rotational coupling with the pinion. The motor is mounted to the case, and is operable to rotate the output shaft in a door-opening direction. The control assembly is mounted to the case, and is configured to operate the motor to drive the output shaft in the door-opening direction in response to an actuating signal.
Patent WO-2021243020-A1 (WO)
Title: Implantable device and method for in-situ detection of circulating cell-free tumor dna
Inventor: KHAN ATIF
IPC: C12Q1/6883
Filed: 2021-05-27
Abstract: Disclosed herein are improvements to detection of circulating tumor DNA (ctDNA). An indwelling device may continually survey plasma volume (thus eliminating serial blood draws and repeat runs of sequencing and also obviating the problem of limited sampling volume in very low allele frequencies). Devices may employ, for example, DNA tweezers or other DNA probes / nano-devices, which may comprise a normal strand (N) with only natural DNA bases, and a complementary weak strand (W) containing one or more inosine (I) substitutions for guanine. An opening strand (O) or "invading strand," which is naturally complementary to N, may be ctDNA to be detected. The operation of the DNA probes may be driven by competition among N, W, and O strands. If O (invading strand) has sufficient affinity to forfeit N from W, the opening operation occurs and a resulting signal may be detected.
Patent WO-2021252420-A1 (WO)
Title: Synthesis of n-(2,4-dinitrophenyl)-4-nitrobenzamide (tnba) using solid acid catalysts
Inventor: SCHULTZ JAMES A
IPC: C07C233/66
Filed: 2021-06-08
Abstract: A method of making N-(2,4-dinitrophenyl)-4-nitrobenzamide from a mixture of 2,4-dinitroaniline, 4-nitrobenzoyl chloride, and solid acid catalyst in an organic solvent, wherein the solid acid catalyst is not soluble in the organic solvent, the solid acid catalyst being an acidic clay, an ion exchange resin, a beta zeolite, a sulfonated tetrafluoroethylene-based fluoropolymer-copolymer, or some mixture of these.
Patent WO-2021257449-A1 (WO)
Title: A machine learning enabled model to optimize design of osseointegration-friendly patient specific 3d printed orthopedic implants
Inventor: HIGGS C
IPC: A61F2/30
Filed: 2021-06-14
Abstract: A method is disclosed for creating a patient-specific orthopedic implant. The method includes creating a numerical representation of an orthopedic implant design based on patient data describing an anatomical, physiological and pathological condition of a patient and simulating a characteristic of the orthopedic implant design based on the numerical representation. The method further includes selecting a patient-specific orthopedic implant design based on the simulated characteristic of the orthopedic implant design and the patient data and constructing at least one patient-specific orthopedic implant based on the selected patient-specific orthopedic implant design.
Patent WO-2023003547-A1 (WO)
Title: Dispositifs fluidiques à multiples propriétés d'interface
Inventor: D'APUZZO FAUSTO
IPC: B81B7/02
Filed: 2021-07-21
Abstract: Un exemple de dispositif microfluidique comprend une première couche optiquement transparente présentant un indice de réfraction. Le dispositif microfluidique comprend également une seconde couche de diffusion optique espacée de la première couche optiquement transparente pour recevoir un premier fluide et un second fluide entre la première couche optiquement transparente et la seconde couche de diffusion optique. L'indice de réfraction est sélectionné pour provoquer une réflexion interne totale là où la première couche s'interface avec le premier fluide et pour provoquer une réfraction là où la première couche s'interface avec le second fluide.f
Patent WO-2022031932-A1 (WO)
Title: Additives for flame retarded polyolefins
Inventor: MCCARNEY JONATHAN P
IPC: C08J3/22
Filed: 2021-08-05
Abstract: This invention provides a flame retardant additive composition which comprises at least one glow suppressant and at least one brominated flame retardant. The glow suppressant is about 0.5 wt% or more of the flame retardant additive composition, based on the total weight of the flame retardant additive composition. The brominated flame retardant contains aromatically-bound bromine and is selected from a) a brominated anionic styrenic polymer having a number average molecular weight of about 750 to about 7500, and/or a bromine content of about 60 wt% to about 77 wt%, b) a brominated anionic chain transfer vinyl aromatic polymer which contains about 70 wt% or more bromine, or a mixture of any two or more of these. Also provided are flame retarded polyolefin compositions that contain at least one glow suppressant and a brominated flame retardant.
Patent WO-2022036090-A1 (WO)
Title: Creating interconnects between dies using a cross-over die and through-die vias
Inventor: AGARWAL RAHUL
IPC: H01L25/00
Filed: 2021-08-12
Abstract: A semiconductor package includes a first die, a second die, and an interconnect die coupled to a first plurality of through-die vias in the first die and a second plurality of through-die vias in the second die. The interconnect die provides communications pathways the first die and the second die.
Patent WO-2022036175-A1 (WO)
Title: Global language education and conversational chat system
Inventor: ISGAR CHARLES
IPC: G09B19/06
Filed: 2021-08-13
Abstract: Described is a global language education and conversational chat system. The system includes a user computing device, a language speaker computing device and a server having a memory, wherein the user computing device and the language speaker computing device are coupled to the server through a connection established by an app operating on each of the user computing device and the language speaker computing device. The system operates to connect the user computing device and the language speaker computing device for an audio or an audio/video chat in the language of the language speaker. The system includes components that may provide recording of chats, analysis of chats and reports on proficiency, accuracy, and the like, of the user speaking the language foreign to the user.
Patent WO-2023027746-A1 (WO)
Title: Exécution conditionnelle d'actions basée sur une histoire d'objet
Inventor: MCMORRIS DANIEL
IPC: G06Q50/18
Filed: 2021-10-13
Abstract: La présente demande concerne des dispositifs et des composants comprenant un appareil, des systèmes et des procédés d'exécution conditionnelle d'actions basée sur une histoire d'objet.
Patent WO-2022086823-A1 (WO)
Title: Superposition graphique modifiable flottante comprenant des propriétés d'objet modèle 3d
Inventor: LIST CHRISTIAN
IPC: G06F30/13
Filed: 2021-10-15
Abstract: Un procédé consiste : à éditer une valeur de propriété d'un objet modèle pour un projet d'investissement à grande échelle ; à afficher un modèle 3D du projet d'investissement à grande échelle dans une interface utilisateur graphique, le modèle 3D ayant une pluralité d'objets modèles ; à sélectionner un ou plusieurs objets modèles dans l'interface utilisateur graphique, formant ainsi un ou plusieurs objets modèles sélectionnés ; à sélectionner également une ou plusieurs propriétés de l'objet modèle sélectionné en vue d'une visualisation dans une superposition graphique, formant ainsi une ou plusieurs propriétés sélectionnées ; à générer en outre une superposition graphique adjacente auxdits objets modèles sélectionnés ou sur chacun de ces derniers, la superposition graphique comprenant des valeurs pour lesdites propriétés sélectionnées ; à modifier une valeur desdites propriétés sélectionnées dans la superposition graphique, formant ainsi une valeur de propriété modifiée.
Patent WO-2022082057-A1 (WO)
Title: Procédés et appareil de détection de défauts dans des systèmes de semi-conducteurs
Inventor: MACHUCA FRANCISCO
IPC: G01N21/956
Filed: 2021-10-15
Abstract: Un système de détection de défaut comprend une source de lumière incohérente et une fixation de source de lumière de collimation pour produire des ondes lumineuses spatialement cohérentes (par exemple, des rayons X) qui sont capables de pénétrer profondément dans un dispositif à l'essai (par exemple, un semi-conducteur). Des changements dans la cohérence spatiale des ondes lumineuses incidentes sur le dispositif à l'essai peuvent être utilisés pour générer une ou plusieurs cartes électroniques qui indiquent une ou plusieurs jauges physiques pour la longueur, la surface, ou le volume, une ou plusieurs concentrations d'éléments ou de distributions dans l'espace, et un ou plusieurs défauts à l'intérieur du dispositif à l'essai, tels que des fissures, des cassures, des trous, et/ou des poches d'air à l'intérieur du dispositif à l'essai.
Patent WO-2022087378-A1 (WO)
Inventor: CAUCCI LUCA
IPC: A61B6/03
Filed: 2021-10-22
Abstract: De nombreux processus biologiques se déroulant à l'intérieur d'un organisme vivant sont imprévisibles dans le temps et dans l'espace, et ne peuvent pas être connus exactement. Ces mécanismes et leurs interactions sont mieux modélisés sous la forme de processus aléatoires physiologiques, dont les statistiques sont entièrement décrites par des fonctions caractéristiques communes. La présente invention concerne des procédés d'estimation de fonctions caractéristiques communes par imagerie de multiples processus aléatoires physiologiques. Cette technologie peut être utilisée pour étudier des maladies complexes, telles que des tumeurs et des infections virales, par imagerie des processus biologiques impliqués dans la progression de la maladie et la réponse au traitement.
Patent WO-2022093770-A1 (WO)
Title: Polythérapie à l'aide d'inhibiteurs de pi3k-akt-mtor et d'agents induisant la ferroptose pour traiter un cancer
Inventor: JIANG XUEJUN
IPC: A61K45/06
Filed: 2021-10-26
Abstract: La présente technologie concerne des méthodes de traitement de cancers à l'aide d'une polythérapie avec un inhibiteur de la voie PI3K-AKT-mTOR (par exemple, un inhibiteur de PI3K, un inhibiteur d'ART, un inhibiteur de mTOR, un inhibiteur de SREBP1, ou un inhibiteur de SCD1) et un agent induisant la ferroptose. L'invention concerne également des kits destinés à être utilisés pour la mise en pratique des méthodes.
Patent WO-2022094043-A1 (WO)
Title: Dispositif d'éclairage à del
Inventor: AN KETAK
IPC: G09F13/22
Filed: 2021-10-28
Abstract: L'invention concerne un dispositif d'éclairage à diodes électroluminescentes (DEL) comprenant un cadre formant une forme et ayant un profil de section transversale pratiquement constant, le cadre ayant une surface interne. Un panneau avant est prévu pour le dispositif d'éclairage à DEL ayant une surface avant dimensionnée et formée pour correspondre pratiquement à la surface interne du cadre, et une surface arrière ayant une forme correspondant pratiquement à la forme de la surface avant et une taille plus petite que la surface avant. Le panneau avant est pourvu d'un profil de bord ayant une profondeur s'étendant de la surface avant à la surface arrière et un adhésif ayant une épaisseur est positionné entre le profil de bord adjacent à la surface arrière du panneau avant et la surface interne du cadre.