baber/WOPTO huggingface dataset:
Patent CA-3044715-A1 (CA)
Title: Fermentation process
Inventor: DE HAAN ANDRE BANIER
IPC: C12P7/40
Filed: 2017-11-29
Abstract: The invention pertains to a process for manufacturing a fermentation product comprising - fermenting under fermentation conditions in an aqueous fermentation medium in a fermentation reactor a carbohydrate source with a microorganism capable of converting the carbohydrate into a fermentation product, wherein the fermentation product is a salt or a product with a boiling point above the boiling point of water, - during the fermentation process withdrawing part of the fermentation medium comprising biomass from the fermentation reactor in the form of a recycle stream, - providing the recycle stream comprising biomass to a pressure vessel wherein the pressure is selected such that the temperature of the recycle stream decreases with a value of 1- 8º C, as compared to the temperature of the fermentation medium in the fermentation reactor, by the evaporation of water - recycling the cooled recycle stream to the fermentation reactor. It has been found that the process according to the invention makes it possible to obtain a homogeneous temperature profile of the fermentation medium with limited occurrence of hot or cool spots within the reactor. This has been found to result in improved fermentation performance.
Patent CA-3045158-A1 (CA)
Inventor: OLDNALL CRAIG
IPC: B02C17/22
Filed: 2017-12-04
Abstract: L'invention concerne un boulon de revêtement (10) comprenant un goujon allongé (12) et une tête (14) pouvant venir en prise avec une première extrémité (16) du goujon (12). La tête (14) comprend une première partie d'extrémité biseautée vers l'intérieur (24) adjacente à sa première extrémité (21). Une partie filetée (18) est disposée adjacente à une seconde extrémité (17) du goujon pour recevoir un écrou (20). La première extrémité (21) de la tête (14) comprend une ouverture chanfreinée vers l'intérieur (28) comportant un filetage interne (30) et la première extrémité (16) du goujon (12) comprend une partie d'extrémité chanfreinée vers l'intérieur (32) comportant un filetage externe (34) de sorte que la première extrémité (16) du goujon (12) puisse venir en prise dans l'ouverture (28) de la tête (14).
Patent CA-3053218-A1 (CA)
Title: Variants de cas9 haute fidelite et leurs applications
Inventor: CERESETO ANNA
IPC: C12N9/22
Filed: 2018-02-14
Abstract: Pour résoudre les limitations dérivées des clivages génomiques non spécifiques de Streptococcus pyogenes Cas9 (SpCas9) et pour identifier des variants avec une fidélité de clivage plus élevée, la présente invention concerne un dosage à base de levure qui permet d'évaluer simultanément l'activité d'activation et de désactivation vers deux cibles génomiques modifiées. Le criblage de variants de SpCas9 obtenus par mutagénèse aléatoire du domaine rouge-II a permis l'identification de réponses avec des rapports d'activation/d'inactivation accrus. La meilleure nucléase d'exécution, évoca9, a été isolée par la combinaison des mutations identifiées dans un seul variant. Des analyses côte à côte avec des variants conçus rationnellement rapportés précédemment ont démontré une amélioration significative de la fidélité de l'évoCas9 de la présente invention.
Patent CA-3054224-A1 (CA)
Inventor: BUELOW RONALD
IPC: C12P21/08
Filed: 2008-05-30
Abstract: The invention relates to transgenic animals lacking endogenous lg and capable of producing transgenic antibodies, as well as methods of making the same. The invention further relates to methods for producing transgenic antibodies in such animals, and transgenic antibodies so produced.
Patent CA-3054756-A1 (CA)
Inventor: PERSSON JAN-ERIK
IPC: B60N2/28
Filed: 2018-03-06
Abstract: The present disclosure relates to an adjustable connecting bar for releasable fastening of a child restraint system to a vehicle seat having mounted anchoring members. The adjustable connecting bar (1) comprises a first and a second elongated bar member (2, 3) telescopically interconnected and arranged for relative displacement along a longitudinal axis (L). The first elongated bar member (2) is provided with a coupling device (4) at an end thereof and the coupling device (4) is transformable from a locked configuration to a release configuration in a first operation step by means of a manually operable actuator (8) which is operatively connected via a maneuvering system (9) to the coupling device. The connecting bar (1) further comprises a latch system (10, 11) housed within the connecting bar (1) for selectively preventing extension and retraction of the connecting bar (1). The latch system comprises a first latch (10) arranged to prevent retraction of the connecting bar (1) when the connecting bar (1) is in an extended end position and the coupling device (4) is in the release configuration. The second latch (11) is arranged to be transferrable from an active state preventing extension of the connecting bar to an inactive state allowing both extension and retraction of the connecting bar (1). The second latch (11) is biased to the active state and transferrable from the active state to the inactive state in a second operation step by means of the manually operable actuator (8). The second operation step is separate from the first operation step and only allowed when the coupling device (4) is in the release configuration. The second latch (11) is arranged to return to the active state upon release of the manually operable actuator (8).
Patent CA-3054915-A1 (CA)
Inventor: BLANPAIN CEDRIC
IPC: G01N33/574
Filed: 2018-03-16
Abstract: The application discloses CD321 as a useful global marker of circulating tumor cells (CTCs) and provides related methods and kits of parts relying on detection of CD321.5
Patent CA-3056511-A1 (CA)
Inventor: BOTELLO ROJAS FAIVER
IPC: E01B1/00
Filed: 2017-03-13
Abstract: The invention relates to a system for securing sleepers in a ballastless track formed by a base plate, sleepers and an interposed elastic intermediate plate, wherein the sleeper body (13) comprises at least one through-hole (12), and the base plate comprises the corresponding blind holes (16) in which a securing pin (17) is embedded, to which a guide rod (22) that can be inserted in the through-hole (12) is joined, via which the sleeper is secured to the base plate in such a way that no additional pretensioning is added to that caused by the positioning of the sleeper thereon, and only a certain amount of vertical movement is permitted, forming a disassemblable assembly of the securing elements and the sleepers.
Patent CA-3057702-A1 (CA)
Title: User interfaces for remote management and control of network-connected thermostats
Inventor: CORCORAN PATRICK
IPC: H04L12/16
Filed: 2011-11-18
Abstract: Provided is one embodiment of a user interface for interacting with network- connected thermostats through a thermostat management system. The user interface identifies a primary enclosure selected from one or more enclosures associated with a thermostat management account while the remaining enclosures are deemed secondary enclosures. The user interface displays the primary enclosure using a primary enclosure selection appearing as an image of a house in a foreground area of the user interface. Adjacent to the primary enclosure selection are round thermostat selections representing each of the network-connected thermostats in the primary enclosure that display an environmental condition, such as temperature, associated with the primary enclosure also in the foreground area. Secondary enclosure selections, representing enclosures other than the primary enclosure, are visually deemphasized in the background area of the user interface when compared with the primary enclosure selection displayed in the foreground area of the interface.
Patent CA-3057774-A1 (CA)
Title: Systems and methods for automatically assessing fault in relation to motor vehicle collisions
Inventor: SKALJIN ROBERT
IPC: G06Q40/08
Filed: 2019-10-07
Abstract: A computer-implemented method of providing a recommendation as to a fault determination for a motor vehicle collision is disclosed. The method may include receiving unstructured text describing the circumstances of the collision. The unstructured text is evaluated an associated intent related to the circumstances of the motor vehicle collision is identified. The intent is mapped to an internal node of a decision tree corresponding to a set of fault-determination rules. The computer then successively prompts and receive input responsive to the prompting that corresponds to details of the circumstances of the collision. The computer may identify, based on the received input, a path through the decision tree ending at a leaf node that corresponds to a fault-determination rule governing motor vehicle collisions that matches the circumstances of the motor vehicle collision. The recommendation is then provided based on that rule. Related systems and computer-readable media are also disclosed.
Patent CA-3057842-A1 (CA)
Title: Nasal delivery tools, systems, and methods of use
Inventor: ROSENTHAL MICHAEL H
IPC: A61B17/24
Filed: 2018-03-28
Abstract: A nasal implant delivery tool includes an inner handle, an outer handle, a needle, and a push rod. The inner handle includes a loading chamber configured to receive a nasal implant. The outer handle is configured to move axially relative to the inner handle. The needle extends distally from the inner handle and has a central lumen and a distal opening. The push rod is configured to move the nasal implant from the loading chamber, through the central lumen, and out the distal opening of the needle. The push rod is coupled to the outer handle such that the push rod moves axially relative to the inner handle when the outer handle is moved axially relative to the inner handle. Also described herein are nasal implant guides and methods of using nasal implant delivery tools and nasal implant guides.
Patent CA-3059097-A1 (CA)
Title: Planar mop configuration with adjustable spacing
Inventor: LECOMPTE PHILLIP
IPC: B08B1/00
Filed: 2018-04-03
Abstract: A biplanar cleaning tool includes adjustable spacers having nested, telescoping or concentric bosses providing for adjustability of the spacing between planar elements of the biplanar cleaning tool.
Patent CA-3061712-A1 (CA)
Title: Methods for treating dravet syndrome
Inventor: MARICICH YURI
IPC: A61K31/00
Filed: 2018-04-26
Abstract: Provided herein are methods of treating Dravet syndrome that include administering an effective amount of a T-type calcium channel antagonist to a subject in need of the treatment.
Patent CA-3062722-A1 (CA)
Inventor: XIA JUPENG
IPC: G06F21/57
Filed: 2018-09-03
Abstract: Implementations of the present specification disclose a method and an apparatus for detecting model security and an electronic device. The method includes the following:  obtaining a discriminator through training by using a GAN framework, a to-be-detected model, and a sample, and discriminating, by using the discriminator, intermediate result data and/or output result data computed by using the to-be-detected model for current input data, to detect whether the to-be-detected model is currently secure.
Patent CA-3064856-A1 (CA)
Title: A holding arrangement for an acoustic transmitter in an acoustic spectroscopy system
Inventor: KOCHER JOHANNES
IPC: G01N29/34
Filed: 2018-06-19
Abstract: There is provided a holding arrangement (100, 200) for holding an acoustic transmitter (101) in place in relation to a container. The arrangement comprises: a body (102) comprising a cavity (104) for holding an acoustic transmitter, the cavity comprising an opening (106) arranged to face said container when said arrangement is attached to a container, wherein the body comprises acoustic damping material, and wherein the cavity is configured to permit movement of an acoustic transmitter in a direction perpendicular to a container surface and to restrict movement of the acoustic transmitter in directions not perpendicular to the container surface when an acoustic transmitter is arranged in said cavity and when said arrangement is attached to a container. There is also provided a measurement arrangement comprising such a holding arrangement.
Patent CA-3067590-A1 (CA)
Inventor: KELLNER JUSTIN
IPC: F16K17/40
Filed: 2018-06-27
Abstract: L'invention concerne un appareil destiné à être utilisé dans une chaîne d'éléments tubulaires comprenant un premier raccord double femelle comportant un alésage, un second raccord double femelle fixé au premier raccord double femelle, le second raccord double femelle comportant un alésage en communication fluidique avec l'alésage du premier raccord double femelle, et un ensemble barrière comportant un élément cassable conçu pour rompre sous l'application d'une pression de fluide à la barrière.
Patent CA-3068896-A1 (CA)
Title: Battery supply circuits, devices to be charged, and charging control methods
Inventor: CHEN SHEBIAO
IPC: H02J7/00
Filed: 2018-12-21
Abstract: The present disclosure provides a battery supply circuit, a device to be charged, and a charging control method, and relates to the field of battery technologies. In the circuit, a first end of a second cell is coupled to a first end of a second switching unit, and a second end of the second cell is coupled to a first end of a switch, a second end of the second switching unit is coupled to a second end of the switch; a first end of a first cell is coupled to the second end of the switch, a second end of the second cell is coupled to a first end of a first switching unit, and a second end of the first switching unit is coupled to the first end of the switch. The disclosure is capable of accommodating various charging schemes for the same device to be charged.
Patent CA-3069604-A1 (CA)
Inventor: WENG ALEXANDER
IPC: A61K31/704
Filed: 2018-07-10
Abstract: The present invention relates to the novel use of saponins comprising acetyl residues on one of their sugar residues. These saponins are able to enhance the transfection efficiency to a surprisingly much higher extent than already known saponins and even than Lipofectamin.
Patent CA-3072452-A1 (CA)
Title: Compositions et methodes de detection de staphylococcus aureus
Inventor: PETERSON PATRICK
IPC: C12Q1/689
Filed: 2018-08-09
Abstract: L'invention concerne des compositions, des kits et des méthodes de détection d'acides nucléiques de Staphylococcus aureus résistant à la méthicilline (SARM). Dans certains modes de réalisation, les compositions, les kits et les méthodes peuvent être utilisés pour détecter un ou plusieurs acides nucléiques SARM à jonction d'extrémité droite SCCmec (MREJ) de type i, ii, iii, iv, v, vi, vii, viii, ix, xii, xiii, xiv, xv, ou xxi, et un ou plusieurs mecA, mecC, et/ou un gène spécifique de S. aureus supplémentaire.
Patent CA-3073995-A1 (CA)
Title: Cartouche de chromatographie et procede de production correspondant
Inventor: ESALA JUHA
IPC: G01N30/60
Filed: 2018-08-29
Abstract: La présente invention concerne une cartouche de chromatographie pré-remplie (10) destinée à une chromatographie flash. La cartouche de chromatographie (10) comprend un cylindre (20) possédant une extrémité scellée à l'aide d'un capuchon (40), un filetage (23) disposé sur la surface cylindrique externe du cylindre (20) et en prise avec un filetage d'accouplement (43) sur la surface cylindrique interne du capuchon (40). Le cylindre comprend au moins une saillie (24) disposée sur la surface cylindrique externe et au-dessous du filetage (23) dans la direction depuis l'extrémité scellée par le capuchon (40). La saillie (24) s'étend sensiblement radialement vers l'extérieur depuis la surface cylindrique externe du cylindre (20). Le capuchon (40) comprend une bride cylindrique (44) disposée en dessous du filetage (43) du capuchon (40). Un élément de verrouillage (46) est disposé sur la bride (44) et s'étend sensiblement radialement vers l'intérieur depuis la surface cylindrique interne de la bride (44). Conjointement avec la saillie (24) du cylindre (20), l'élément de verrouillage (46) forme une liaison mécanique qui fixe le capuchon (40) de telle sorte qu'il ne puisse pas être dévissé du cylindre (20).
Patent CA-3074244-A1 (CA)
Inventor: CAZENEUVE CECILE
IPC: C12Q1/68
Filed: 2018-08-28
Abstract: The present invention belongs to the field of methods to validate genotyping results obtained by Next-Generation Sequencing (NGS) for a series of patients, to detect sample mix-ups and prevent misdiagnosis. In particular, the present invention relates to a method to validate Next-generation sequencing (NGS) genotyping results of a panel of genes tested in a series of at least 2 patients characterized in that said validation is provided by SNP profiling assay,adapted for allele-specific multiplex PCR, allowing accurate validation of NGS data by sample pairing. The present invention also relates to a kit comprising PCR multiplex reagents and/  or NGS oligonucleotide probes or primers designed to capture or amplify sequences comprising a combination of at least 8 SNPs and its use for validating NGS genotyping results.
Patent CA-3086018-A1 (CA)
Inventor: VAITHILINGAM PANCHALINGAM
IPC: E21B41/02
Filed: 2019-01-08
Abstract: An additive, such as an aminal, a dibutylamine, or combinations thereof, may treat a system having a corrosion inhibitor in the form of at least one sulfur species and/or at least one phosphorous-containing compound. The additive may be introduced or added to the corrosion inhibitor within an aqueous system, an aerobic system, and/or an anaerobic system to inactivate the sulfur species and/or the phosphorous-containing compounds.
Patent CA-3087171-A1 (CA)
Inventor: AFZAL DANIAL
IPC: G06Q50/30
Filed: 2018-12-20
Abstract: La présente invention concerne un système perfectionné de mise en correspondance de transport, ainsi que des procédés et des supports lisibles par ordinateur correspondants. Selon des modes de réalisation de l'invention, un système de mise en correspondance de transport reçoit des informations de session en provenance d'un dispositif informatique de demandeur en réponse à un ou plusieurs événements de session. Le système utilise les informations de session reçues pour déterminer la probabilité que la session associée sur le dispositif informatique de demandeur entraîne une demande de transport. Si la probabilité déterminée est supérieure à une quantité seuil, le système génère une distribution à l'avance, qui correspond à la session associée, à un dispositif informatique de fournisseur. Le système réserve ensuite le dispositif informatique de fournisseur et génère une distribution prédite pour le dispositif informatique de fournisseur réservé.
Patent CA-3087567-A1 (CA)
Inventor: ISAACSON S RAY
IPC: A61M25/06
Filed: 2019-01-03
Abstract: A medical instrument or device, such as a catheter, has echogenic properties, in addition to or as an alternative to radiopaque properties, to facilitate detection of the medical instrument or device during medical procedures using suitable imaging methods, such as ultrasound imaging and/or x-ray imaging methods. In example embodiments, an example catheter has a relatively increased radiopacity and echogenicity to facilitate a clinician with detecting the catheter with ultrasound imaging and/or x-ray imaging methods to assist the clinician with the insertion, placement, and/or maintenance of the catheter, for example.
Patent CA-3091218-A1 (CA)
Title: Article revetu ayant un revetement protecteur contenant du nitrure de silicium et/ou de l'oxynitrure de silicium
Inventor: GANJOO ASHTOSH
IPC: C03C17/34
Filed: 2019-02-13
Abstract: Un article revêtu comprend un substrat, une couche fonctionnelle sur au moins une partie du substrat, et un revêtement protecteur sur au moins une partie de la couche fonctionnelle, une couche supérieure de la couche fonctionnelle étant une couche d'oxyde métallique, et le revêtement protecteur comprenant une couche de nitrure métallique et une couche d'oxynitrure métallique qui est disposée entre et en contact avec au moins une partie de la couche de nitrure métallique et de la couche d'oxyde métallique de la couche fonctionnelle.
Patent CA-3092078-A1 (CA)
Inventor: LIU LU
IPC: C12N15/62
Filed: 2019-03-12
Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.
Patent CA-3092239-A1 (CA)
Title: Argon associe a une thrombectomie en cas d'accident vasculaire cerebral ischemique
Inventor: FARJOT GERALDINE
IPC: A61P9/10
Filed: 2020-09-04
Abstract: L'invention concerne un médicament gazeux inhalable contenant de l'argon gazeux pour une utilisation en association avec une thrombectomie mécanique pour, traiter, atténuer ou résorber des lésions cérébrales consécutives à un accident vasculaire cérébral ischémique (AVCi) chez un individu. De préférence, la proportion volumique d'argon est comprise entre 30 et 79%. La thrombectomie mécanique peut s'accompagner d'une thrombolyse médicamenteuse pour dissoudre le caillot et fluidifier le sang du patient.
Patent CA-3094326-A1 (CA)
Inventor: TAKAHASHI KENZO
IPC: H02K44/06
Filed: 2019-03-18
Abstract: A molten metal pump provided with a pump chamber unit and a drive unit, wherein ejection and suction are performed by driving molten metal in a pump chamber of the pump chamber unit by means of the drive unit. The pump chamber unit comprises an outer cylinder and an inner cylinder detachably accommodated in the outer cylinder. The outer cylinder is configured as a bottomed cylindrical body having an outer cylinder bottom wall and an outer cylinder side wall. The inner cylinder is configured as a bottomed cylindrical body having an inner cylinder bottom wall and an inner cylinder side wall. The molten metal pump is further provided with a ring-shaped spacer which is interposed between an inner surface of the outer cylinder bottom wall and an outer surface of the inner cylinder bottom wall in a sealed state and detachably. The spacer defines and forms a space between the inner surface of the outer cylinder bottom wall and the outer surface of the inner cylinder bottom wall into a pump chamber. The spacer can be replaced with another spacer with a different height to vary the interval between the outer cylinder bottom wall and the inner cylinder bottom wall, whereby the volume of the pump chamber can be changed and pumping capacity can be adjusted.
Patent CA-3095137-A1 (CA)
Inventor: XIONG MAY
IPC: A61K31/724
Filed: 2019-03-26
Abstract: Disclosed herein are a polyrotaxane conjugated metal chelators and selectively cleavable linkers. The compositions have prolonged plasma residence time, and upon contact with the appropriate chemical environment, are cleaved and then renally and fecally cleared.
Patent CA-3095255-A1 (CA)
Title: Systems, apparatus and methods for separating actinium, radium, and thorium
Inventor: ROBERTSON ANDREW KYLE HENDERSON
IPC: G21G1/10
Filed: 2019-03-26
Abstract: A method of separating actinium and/or radium from proton-irradiated thorium metal. The thorium metal is irradiated to produce isotopes including thorium, actinium and/or radium. The resultant product is dissolved in solution and a selective precipitant is used to precipitate a bulk portion of the thorium. The precipitated thorium can be recovered. Chromatography is carried out on the remaining solution to remove residual thorium and to separate the actinium from the radium.