baber/WOPTO huggingface dataset:
Patent AU-2007293774-C1 (AU)
Title: Acyclic amine inhibitors of nucleoside phosphorylases and hydrolases
Inventor: EVANS GARY BRIAN
IPC: C07D487/04
Filed: 2007-09-07
Granted: 2014-12-18
Abstract: The invention relates to compounds of the general formula (I) which are inhibitors of purine nucleoside phosphorylases (PNPs) and/or nucleoside hydrolases (NHs). The invention also relates to the use of these compounds in the treatment of diseases and infections including cancer, bacterial infections, protozoal infections, and T-cell mediated disease and to pharmaceutical compositions containing the compounds.
Patent AU-2009302945-C1 (AU)
Title: Heart help device, system, and method
Inventor: FORSELL PETER
IPC: A61M60/876
Filed: 2009-10-12
Granted: 2016-04-21
Abstract: An implantable device for improving the pump function of the heart of a human patient by applying an external force on the heart muscle is provided. The device comprises at least one heart contacting organ. The heart contacting organ is adapted to be movable to change the position of said force exerted on the heart after the implantable device has been implanted in the human patient. The invention further relates to a method of using said device.
Patent AU-2012217070-C1 (AU)
Title: Detecting a level of use in a communications network
Inventor: DECARREAU GUILLAUME
IPC: H04W72/04
Filed: 2012-02-15
Granted: 2016-08-11
Abstract: A level of use of a first radio resource is detected and a flag is set in system information if the level of use of the first radio resource is above a predetermined threshold. The system information is updated to the network.
Patent AU-2012308416-C1 (AU)
Title: Impact extruded containers from recycled aluminum scrap
Inventor: SILES JOHN L
IPC: C22C21/00
Filed: 2012-09-14
Granted: 2016-11-24
Abstract: Novel aluminum alloys are provided for use in an impact extrusion manufacturing process to create shaped containers and other articles of manufacture. In one embodiment blends of recycled scrap aluminum are used in conjunction with relatively pure aluminum to create novel compositions which may be formed and shaped in an environmentally friendly process. Other embodiments include methods for manufacturing a slug material comprising recycled aluminum for use in the impact extraction process.
Patent AU-2013204018-C1 (AU)
Title: Framework-shuffling of antibodies
Inventor: WU HERREN
IPC: C12P21/08
Filed: 2013-04-11
Granted: 2015-11-19
Abstract: The present invention relates to methods of reengineering or reshaping antibodies to reduce the immunogenicity of the antibodies, while maintaining the immunospecificity of the antibodies for an antigen. In particular, the present invention provides methods of producing antibodies inmmunospecific for an antigen by synthesizing a combinatorial library comprising complementarity determining regions (CDRs) from a donor antibody fused in frame to framework regions from a sub-bank of framework regions. The invention also provides method of producing improved humanized antibodies. The present invention also provides antibodies produced by the methods of the invention.
Patent AU-2013364757-C1 (AU)
Title: Laver-snack made of laver and cereal sheets and process of producing the same
Inventor: CHUNG SUYEON
IPC: A23L17/60
Filed: 2013-11-25
Granted: 2016-10-06
Abstract: Provided is a laver-snack produced by attaching a cereal sheet to a laver sheet to obtain a double-layer sheet and then roasting the double-layer sheet, and a method of producing the laver-snack.
Patent AU-2018244592-C1 (AU)
Title: Chimeric polypeptides and methods of altering their localisation in the cell membrane
Inventor: SANTORO STEPHEN
IPC: A61K38/17
Filed: 2018-03-28
Granted: 2021-07-08
Abstract: Methods and compositions are provided for reversibly localizing proteins to the exterior part of the cell surface. Essentially, the protein must comprise, in addition to a transmembrane domain, also a hormone receptor like the estrogen receptor alpha or the progesterone receptor. Compositions provided herein can include nucleic acids that encode polypeptides of interest and the ligand binding domain (LBD) of a nuclear hormone receptor. Medical applications are provided, including controlling the toxicity of CAR T cells.
Patent AU-2020230264-C1 (AU)
Title: Cytotoxic and anti-mitotic compounds, and methods of using the same
Inventor: WINTERS GEOFFREY C
IPC: A61P35/00
Filed: 2020-09-09
Granted: 2022-09-22
Abstract: CYTOTOXIC AND ANTI-MITOTIC COMPOUNDS, AND METHODS OF 
USING THE SAME 
Abstract 
Compounds having cytotoxic and/or anti-mitotic activity are disclosed.  
Methods associated with preparation and use of such compounds, as well as 
pharmaceutical compositions comprising such compounds, are also disclosed. Also 
disclosed are compositions having the structure: (T)-(L)-(D), wherein (T) is a 
targeting moiety, (L) is an optional linker, and (D) is a compound having cytotoxic 
and/or anti-mitotic activity.
Patent RU-2167790-C1 (RU)
Inventor: KISELEV V I
IPC: B64G1/34
Filed: 2000-02-21
Granted: 2001-05-27
Abstract: FIELD: space engineering; designing and development of artificial satellites injected into orbits at altitude of 200 to 700 km. SUBSTANCE: according to invention, overall dimensions, mass and aerodynamic characteristics of satellite are selected depending on apogee and perigee altitudes of working orbit, as well as on preset satellite existence time. These characteristics ensure ballistic coefficient of satellite whose upper bound is found from special relationship. Relative maximum permissible random deviations due to technological errors, deviations of drag coefficient and mass of satellite are introduced into this relationship. EFFECT: extended operational capabilities of satellite due to avoidance of premature recovery from working orbit because of atmospheric braking. 1 dwg, 2 tbl
Patent RU-2162442-C1 (RU)
Inventor: TATARINOV A N
IPC: C01G15/00
Filed: 2000-07-03
Granted: 2001-01-27
Abstract: FIELD: recovery and purification of thallium including isotope enriched thallium prepared by electromagnetic separation method. SUBSTANCE: pure metallic thallium is dissolved in concentrated nitric acid by addition of concentrated hydrochloric acid at   ratio of 3:1, and solution is maintained at 80-90 C till it becomes disclosed. Thallium (I) is oxidized to thallium (III). Thallium hydroxide is deposited by addition of ammonia. After washing and filtration, Tl 2 O 3 ×H 2 O dehydration is carried out at 200-300 C. Method makes it possible to recover 99.6-99.8 of thallium in the form of oxide. Method uses standard equipment, inexpensive reactants and insignificant amount of electric energy. EFFECT: more efficient preparation method. 6 ex
Patent RU-2167071-C1 (RU)
Inventor: GALKA V L
IPC: H02M7/5387
Filed: 2000-09-21
Granted: 2001-05-20
Abstract: FIELD: railway transport; power supply equipment. SUBSTANCE: proposed invention is designed for use in power dc/ac conversion circuits. Device has current receiver, choke, converter with A, B, C phase conversion units, PLUS and MINUS poles circuit capacitors, converter control unit, converter parameters intelligent sensor, electric motor instantaneous position intelligent sensor with ballast resistor, converter and electric motor parameters comparator unit, threshold devices unit, two switching units of balancing capacitors and discharge resistors, two banks of balancing capacitors and two banks of discharge resistors. Device provides operative protection against self-excitation and hunting of induction motor at initial stage and several times reduces changes of voltage, current and frequency in stator circuit. EFFECT: reduced requirements to circuit isolation, improved conditions of motor control, increased service life of equipment. 2 dwg
Patent RU-2177132-C1 (RU)
Title: Melting furnace
Inventor: GOTOVCHIKOV V T
IPC: G21F9/00
Filed: 2000-10-19
Granted: 2001-12-20
Abstract: FIELD: metallurgy, in particular, meting furnaces for production of metals and alloys, processing of metal and solid mixed radioactive waste, as well as of irradiated heat-producing elements and heat-producing assemblies containing used nuclear fuel. SUBSTANCE: the melting furnace has a metal melting cooled pot that is translucent for electromagnetic field, and a bottom plate with cooled. The bottom plate and/or side wall of the melting pot accommodates one or several draining devices made in the form of induction melting assemblies. The draining devices positioned in the bottom plate are made in the form of metal sectionalized cooled melting ports that are translucent for electromagnetic field with inductors arranged around the melting pots. The draining devices positioned in the side wall of the melting pot are made in the form of inclined metal sectionalized cooled chutes that are translucent for electromagnetic field, with inductors arranged around the chutes. The melting furnace provides for maintaining the temperature of the drained melt at the preset level; preserves homogeneity of the drained melt as a result of its electromagnetic stirring at drainage, prevents pollution of the obtained metal by material of which the draining device is made as a result of absence of some metals and slags that are not resistant to corrosion, prevents absorption of the melt components by the draining device, and thus does not form a new type of waste in the form of used structural materials, provides for continuous process of melting without crystallization and cooling of the products of melting inside the melting pot at a complete automatic and remote control and durability of the draining devices, since they can work for several years and need no intermediate surface conditioning and repairs with participation of the attending personnel. EFFECT: enhanced efficiency and durability. 15 cl, 6 dwg
Patent RU-2182234-C1 (RU)
Title: Valve actuating mechanism
Inventor: SMOL SKIJ L A
IPC: F01L1/28
Filed: 2000-11-28
Granted: 2002-05-10
Abstract: FIELD: mechanical engineering; internal combustion engines; piston machines. SUBSTANCE: ring 9 of intake valve 8 enclosing ting bridge 6 of cylinder head 1 separating outlet channel 2 and intake ring channel 5 in zone of valve adjoining is provided with air flow stabilizers 11 at side of channel 5. Stabilizers are directed along axis of ring 9 to reduce hydraulic resistance. For higher effect, intake channel including inlet channel 4 and ring channel 5 connected to channel 4 is provided with at least one fixed air flow stabilizer 12. EFFECT: reduced hydraulic resistance of valves in valve actuating mechanism. 3 dwg
Patent RU-2174432-C1 (RU)
Title: Membrane apparatus with nonstationary hydrodynamics
Inventor: KRETOV I T
IPC: B01D63/06
Filed: 2000-12-04
Granted: 2001-10-10
Abstract: FIELD: separation, concentration and desalination of various solutions by reverse osmosis and ultrafiltration; food-processing, pharmaceutical and microbiological industries and agroindustrial complexes. SUBSTANCE: membrane apparatus includes tubular membrane modules made in form of porous bodies with semi-permeable membranes applied on inner surface, branch pipes for introducing starting solution and discharge of filtrate and concentrate, semi-permeable hose located coaxially relative to membrane surface, members interconnected by chain links which are spherical in shape and are set in motion by means of drive and driven sprockets. Spherical members are movable in impermeable hose along membrane surface. EFFECT: increased productivity of apparatus due to improved hydrodynamic conditions of flow of separable solution. 3 dwg
Patent RU-2179237-C1 (RU)
Title: Method of oil pool development
Inventor: MINNULLIN R M
IPC: E21B43/20
Filed: 2001-03-06
Granted: 2002-02-10
Abstract: FIELD: oil-producing industry. SUBSTANCE: method includes injection of working agent through injection wells and periodic withdrawal of product through producing wells. Periodic withdrawal of product through producing wells is carried out from at least every producing well. For selection of well, it is shut-in and annulus pressure is measured. With rise of annulus pressure for 1-2 MPa, periodic withdrawal of product is carried out under cyclic conditions: operation - shut-in. Well is shut in when annulus pressure drops by a factor of 1.5-2.0 and it is started to operate with annulus pressure rise by a factor of 1.5-2.0. Proposed method is used in development of water-flooded oil pool. EFFECT: higher rate of oil recovery.
Patent RU-2191583-C1 (RU)
Title: Method for correcting hemorrhagic shock
Inventor: LESKOVA G F
IPC: A61K31/66
Filed: 2001-03-28
Granted: 2002-10-27
Abstract: FIELD: medicine. SUBSTANCE: one should intravenously inject the preparation of multilayer liposomes at the dosage of 1.0 mg/kg body weight taken at the concentration of 0.5 mg/ml distilled water. The method provides the restoration of hepatic lipids peroxidation, phospholipid composition of plasmatic membranes of hepatocytes, and membranous fractions of medulla oblongata mitochondria and frontal lobes of large cerebral hemispheres. EFFECT: higher efficiency of correction. 3 dwg, 5 ex, 2 tbl
Patent RU-2176691-C1 (RU)
Title: Method for determination of compression stress in elastic clamp of drawing rollers
Inventor: KAPITANOV A F
IPC: D01H5/80
Filed: 2001-04-05
Granted: 2001-12-10
Abstract: FIELD: equipment for spinning of natural and chemical fibres for determination of compression stress in a typical mechanism of spinning production-elastic clamp of the drawing rollers. SUBSTANCE: dactyloscopic film repeating the shape of the roll of the drawing rollers in the zone of contact is used as the measuring member. The dactyloscopic film is introduced in the elastic clamp with the sensitive layer turned towards the fibrous product, the contacts are fixed on it in the form of roll marks. The compression stress in the elastic clamp of the drawing rollers is determined according to the quantity of contacts per unit of area of the dactyloscopic film and according to the preliminarily determined dependence between the number of contacts per unit of area of the dactyloscopic film and the compression stress. Determination of the preliminary dependence is accomplished by placement of dactyloscopic film on the device bottom, then a fibrous product is laid on it, and the load placed above the fibrous product provides for a fixed compression stress, which then is varied. The quantity of contacts per unit of area of the dactyloscopic film is determined for each fixed compression stress. EFFECT: expanded potentialities due to determination of the compression stress over the entire width of the land. 2 cl, 3 dwg
Patent RU-2193332-C1 (RU)
Inventor: NOVIKOVA M V
IPC: A23L17/00
Filed: 2001-05-15
Granted: 2002-11-27
Abstract: Изобретение относится к рыбной промышленности, а именно к производству продуктов переработки гибробионтов для диетического питания. Диетический продукт содержит фарш рыбный, крахмал, сухое, молоко, яйцо, компоненты переработки моллюсков, а также сахар-песок, кислоту аскорбиновую, фосфат натрия, нитрит натрия и масло растительное. В качестве компонентов переработки моллюсков берут гонады кальмара и мидийный гидролизат МИГИ-К ЛП. Способ получения диетического продукта включает подбор компонентов, измельчение и смешивание. Рыбное сырье измельчают до получения фарша с разной степенью измельчения от 1 мм до 1 см, смешивание проводят в куттере в течение 5-8 мин, при этом компоненты вносят в следующей последовательности: фарш рыбный мелко измельченный, нитрит натрия, кислоту аскорбиновую, мидийный гидролизат, гонады кальмара, фосфат натрия, сахар-песок, молоко сухое, яйцо куриное свежее, крахмал, фарш рыбный крупно измельченный, масло растительное. Полученную массу формуют в колбасную оболочку и подвергают термообработке до достижения в центре батона 70-75 o С с последующим охлаждением. Изобретение позволит повысить биологическую и пищевую ценность продукта и расширить ассортимент диетических продуктов в виде колбасно-ветчинных изделий. 2 с. и 2 з. п. ф-лы, 1 табл.
Patent RU-2193633-C1 (RU)
Title: Reinforced-concrete half-frame
Inventor: NOVIKOVA O N
IPC: E04B1/38
Filed: 2001-06-05
Granted: 2002-11-27
Abstract: FIELD: construction engineering; designed for prefabricated building frames. SUBSTANCE: reinforced-concrete half-frame includes post and crossbar, supporting parts of post and cross-bar, embedded parts of post and cross-bar supporting parts. Post supporting part in tension zone has reinforcing member with thread on its end, and in compression zone has pin with protruding conical part whose body has through hole and circular projection. Cross-bar supporting part in tension zone has through hole, and in compression zone has metal tube with rubber ring fitted on its lower base. Diameter of pin conical part lower base exceeds inner diameter of metal tube. EFFECT: reduced labor input in production processes. 3 dwg
Patent RU-2197837-C1 (RU)
Inventor: NIKIFOROV E A
IPC: A23K1/175
Filed: 2001-08-16
Granted: 2003-02-10
Abstract: FIELD: agriculture, particularly, fodder production. SUBSTANCE: method involves using, as a mineral silicon-containing feed additive, is diatomite with 81.30-85.60% content of silica or opoka with 84.10-89.62% content of silica. Proposed opal-christobalit rocks (diatomite, opoka), as natural formations, contain a number of chemical elements, and it allows to use them as biologically active additives to animal's ration. EFFECT: broadened raw material base for feed production. 2 cl, 1 tbl
Patent RU-2199287-C1 (RU)
Inventor: STARYKH V S
IPC: A61L27/24
Filed: 2001-08-27
Granted: 2003-02-27
Abstract: FIELD: medicine, neurosurgery. SUBSTANCE: defect's osseous edges should be refreshed to fix a defect-shaped rigid plate overlapped. Then dura mater should be fixed with ligatures made of prolongly resolving material to the plate through drilled canals and at the distance equal to defect's thickness value. Moreover, at first, one should lubricate refreshed osseous edges with collapane gel, then osseous defect should be filled with collapane-made granules covered with its gel, then cranial defect should be covered with a collapane-made plate with gentamicin antibiotic. The method enables to decrease complications and increase reliability of osseous tissue regeneration. EFFECT: higher efficiency of operation.
Patent RU-2201726-C1 (RU)
Inventor: PETRAKOVA R K
IPC: A61F5/01
Filed: 2001-09-11
Granted: 2003-04-10
Abstract: FIELD: medicine, in particular, traumatology and orthopedics. SUBSTANCE: reclinator has two parts, each made in the form of shoulder loop connected to profiled base joined to shoulder belt, and fastener whose parts are positioned on belts. Bases with belts are manufactured from layered cotton. Shoulder loops are made from felt-layered cotton, are stitched to respective bases and their top parts are connected to base by means of elastic tape. Parallel lines are stitched on bases and plates are inserted between stitched lines. Fastener has metal frame and velcro tape, which are arranged on belts. Reclinator is used for treating kyphoic spine deformation, child's disturbed posture, deformed winged scapula. EFFECT: increased efficiency by creating substantial correcting forces while retaining form of jacket even after prolonged wearing. 1 dwg
Patent RU-2199901-C1 (RU)
Title: Method of preparing candied berries
Inventor: KVASENKOV O I
IPC: A23L21/10
Filed: 2001-10-08
Granted: 2003-03-10
Abstract: FIELD: food-concentrates industry. SUBSTANCE: prepared berry raw material is saturated with sugar in syrup with content of dry substances of 50-75% by mass and with addition of a preparation. The preparation is produced by successive extraction of biomass of Mortierella sclerotiella micromycete with nonpolar extracting agent under above-critical condition with water, alkali, water, acid, alkali and water with the following combination of the first extract with solid residue. Saturation is conducted at temperature lower than that of syrup boiling up to content of dry substances in raw material equal to 50-55%. Drying of candied berries is carried out up to moisture content of 20-25%. Using of extract of biomass of Mortierella sclerotiella micromycete allows to strengthen cell structure of raw material, and it preserves form and volume of berries in end product. Method provides for production of candied berries with less stickiness, more mild taste, and pronounced aroma of initial raw material without caramel tints, mild consistency, and products do not subjected to color changing. EFFECT: improved organoleptical properties and reduced losses of native biologically active substances with simultaneous improvement of chemical composition of end product, and its increased output. 3 cl
Patent RU-2198704-C1 (RU)
Title: Method for treating the cases of pharyngitis
Inventor: SHIKINA L A
IPC: A61N7/00
Filed: 2001-10-16
Granted: 2003-02-20
Abstract: FIELD: medicine. SUBSTANCE: method involves irrigating rhinopharynx by means of low frequency ultrasonic radiation produced by an apparatus with 0.01% Miramistin solution with Dimexin added in 50:1 ml concentration, respectively. Irrigation lasts for 1-5 min including pause time. Then, rhinopharyngeal mucous membrane is treated with ultrasonic radiation by means of apparatus wave guide end face during 3-5 s 2-3 mm far from mucous membrane. EFFECT: enhanced effectiveness of treatment. 2 cl, 1 dwg
Patent RU-2197606-C1 (RU)
Title: Gas-liberating foaming composition
Inventor: RAGULIN V V
IPC: E21B43/22
Filed: 2002-02-08
Granted: 2003-01-27
Abstract: FIELD: oil producing industry; applicable in foam treatment of wells and bottom-hole formation zones. SUBSTANCE: gas-liberating foaming composition including water, sodium nitrite, sulfamic acid and foaming agent contains additionally reagent neutralizing sulfamic acid, with the following ratio of components, wt.%: sodium nitrite, 0.9-20.9; sulfamic acid, 0.9-16.4; reagent neutralizing sulfamic acid, 0.2-7.9; foaming agent, 0.1-2.5; water the balance. Reagent neutralizing sulfamic acid is used in the form of aqua ammonia, ammonium carbonate or hydrocarbonate or their mixture. Said neutralizing reagent is sufficient for neutralization of sulfamic acid up to 50-97%. Gas-liberating foaming composition has foam stabilizer in amount of 0.05-0.2 wt. % for 100% of composition. Foam stabilizer is used in the form of water-soluble polymer, for instance, polyacrylamide. EFFECT: higher gas-liberating foaming ability of composition, reduced corrosiveness and extended assortment of chemical substance for production of foaming composition. 5 cl, 2 tbl