baber/WOPTO huggingface dataset:
Patent PT-1114819-E (PT)
Title: Process to prepare oxazolidinones
Inventor: PEARLMAN BRUCE A
IPC: C07D521/00
Filed: 1997-03-28
Abstract: A 5-aminomethyl-substituted oxalidine amide is prepared by reacting a 5-hydroxymethyl-substituted oxazolidinone alcohol with a sulfonylating agent, and reacting the resultant oxazolidinone sulfonate ammonia. The sulfonates are new conpounds.
Patent PT-1255716-E (PT)
Title: Segment synthesis
Inventor: SLOOTSTRA JELLE WOUTER
IPC: C40B40/06
Filed: 2001-02-16
Abstract: The invention relates to the field of molecular recognition or detection of discontinuous or conformational binding sites or epitopes corresponding to a binding molecule, in particular in relation to protein-protein protein-nucleic acid, nucleic acid-nucleic acid or biomolecule-ligand interactions. The invention provides a synthetic molecular library allowing testing for, identification, characterisation or detection of a discontinuous binding site capable of interacting with a binding molecule, said library having been provided with a plurality of molecules, each molecule of said molecules comprising at least one first segment linked to a second segment, each segment having the capacity of being a potential single part of a discontinuous binding site.
Patent PT-1286594-E (PT)
Inventor: TOMATIS STEFANO
IPC: A21C11/00
Filed: 2001-05-08
Abstract: A flattening roller (38) is supported on horizontal guides (32, 34) and rolls alternately in opposite directions along the guides. A tray (30) is arranged horizontally between the guides, and is progressively lifted to approach to the cylindrical surface of the roller. The tray turns by a quarter turn around a vertical axis at the end of each stroke of the roller along the guides. A lump of dough placed on the tray is progressively flattened to a thin, round shape.
Patent PT-1285098-E (PT)
Inventor: ZAHN ANDREAS
IPC: C21D9/30
Filed: 2001-05-15
Abstract: In a process for the induction hardening of crankshafts with at least one connecting-rod pin and with at least two main bearings, in particular for the hardening of the at least one connecting-rod pin, by means of a contactlessly operating inductor, the crankshaft performs a rotational movement during the hardening of the at least one connecting-rod pin. The center axis of the at least one connecting-rod pin to be hardened is used as the axis for the rotational movement of the crankshaft.
Patent PT-1323665-E (PT)
Inventor: YANG HENG-TE
IPC: B67B7/04
Filed: 2002-10-24
Abstract: A telescoping barrel (4) is provided on the mouth of a bottle to make the needle penetrate through a cork (90) sealing the bottle mouth. A press-in member (71), provided on a cover (7), is depressible to propel a gas container (8) downward and force gas flow from the gas container through the gas inlet (50) of a needle (5) such that the cork can be extracted upwardly.  The gas container is placed into an interior barrel (3) to align the gas container with the gas inlet of the needle. The cover is provided at the upper portion of an exterior barrel (2).
Patent PT-1259088-E (PT)
Title: Method for notifying the arrival of an event to a mobile terminal, and mobile terminal for this method
Inventor: ERIC VALADE
IPC: H04M1/7243
Filed: 2002-05-06
Abstract: The incoming event type is compared with an incoming event type identifier contained in the activated incoming event management profile. A notification message is sent to the terminal, whose identifier is contained in the profile, if the incoming event type matches with the event type of the profile. An independent claim is included for mobile telephone.
Patent PT-1357901-E (PT)
Title: Process for preparing particles
Inventor: SUNDHOLM GORANN ERIC
IPC: A61K31/167
Filed: 2002-01-21
Abstract: A process for preparing particles of a substance, such as a protein or polypeptide, comprising: (a) preparing a first liquid comprising water, the substance and a modulator, wherein the modulator has a solubility in water which decreases with increasing temperature; and (b) contacting the first liquid with a second liquid comprising a fluid gas and an organic solvent using an anti-solvent fluid gas technique under conditions of temperature and pressure which result in the precipitation of particles comprising the substance, wherein the temperature of the first liquid is at or above the cloud point temperature of the first liquid when the first liquid contacts the second liquid. Also claimed are particles obtained according to the process and compositions containing the particles.
Patent PT-1385762-E (PT)
Title: Container gripping clamp
Inventor: GRAFFIN ANDRE
IPC: B65G47/84
Filed: 2002-05-03
Abstract: The invention relates to a gripping clamp for receptacles, each comprising a body and a neck having a projecting collar presenting a substantially radial bearing face beside the body, the clamp having first and second jaws, the first jaw being arranged to co-operate with the bearing face of the collar and the second jaw being arranged to co-operate with a zone of the neck that extends in the vicinity of the bearing face on its side facing away from the body, when the clamp is in a closed, gripping position.
Patent PT-1411960-E (PT)
Inventor: HOFFPAUER DIANE WRIGHT
IPC: A23L33/155
Filed: 2002-06-21
Abstract: A fortified rice bran food product for preventing and/or treating cardiovascular disease in animals, contains in admixture:(a) rice bran as a carrier;(b) at least about 12.5 milligrams of vitamin B1 per 30 grams of the rice bran;(c) at least about 250 milligrams of vitamin C per 30 grams of the rice bran;(d) at least about 12.5 milligrams of vitamin B6 per 30 grams of the rice bran;(e) at least about 75 micrograms of vitamin B12 per 30 grams of the rice bran;(f) at least about 100 International Units of vitamin E per 30 grams of the rice bran;(g) at least about 0.25 milligrams of folic acid per 30 grams of the rice bran; and(h) at least about 250 milligrams of omega-3-fatty acids per 30 grams of the rice bran.A method for preventing and/or treating cardiovascular disease in an animal involves orally administering a therapeutically effective amount of the fortified rice bran food product to the animal for a therapeutically effective period of time.
Patent PT-1430220-E (PT)
Inventor: DAVIS BARRY V
IPC: F03B13/10
Filed: 2002-09-16
Abstract: An apparatus is disclosed for a turbine for generating electrical power from water or air flow comprising at least one rotor disk having a plurality of hydrofoil blades, guide vanes, a cylindrical housing, and a generator means. A rim generator comprising a magnet race rotor rim and fixed stator coils in the housing is used. The apparatus is fitted with a screen to stop the ingress of debris and marine life, and a skirt augmenter device to reduce the Betz effect. The apparatus is preferably for sub-sea deployment and driven by tidal currents, but may be powered by river current or wave driven air or by wind. The apparatus may be deployed on at least one telescoping pole, tethered to the sea-bed and kept buoyant by buoyant concrete in the housing, or inserted in a dam, under a barge or in a tidal power array.
Patent PT-1432779-E (PT)
Title: Method and apparatus for the gasification of fuel in a fluidised bed reactor
Inventor: KURKELA ESA
IPC: C10J3/54
Filed: 2002-10-01
Abstract: The invention relates to a method and apparatus for gasifying fuel in a fluidised bed reactor (1) containing fluidised solid material particles. The fuel (8) is introduced into the reactor bottom part, and product gas (10) formed in gasification is led from the reactor top to a separator, such as a cyclone (11), which separates solid particles from the gas for recirculation to the reactor. In accordance with the invention, a bubbling fluidised bed (2) containing coarser particles, and above this, a circulating bed containing finer particles are maintained in the reactor by recirculating the particles separated from the product gas to the reactor, to the top of the bubbling fluidised bed or above this. The reactor may comprise a lower part (2) for the bubbling fluidised bed and an upper part (4) larger in cross-section for the circulating fluidised bed, the speed of the ascending gas flow in the circulating bed being equal to or lower than that of the bubbling bed. The separating limit in the cyclone may be adjusted such that the discharged product gas flow entrains solid particles, which have a binding effect on tacky ash particles. The product gas is cooled in two successive heat exchangers (19, 20) before filtration of the gas. The method is suitable for gasification of biomasses and recycled fuels forming tars and/or containing chlorine, thus providing a solution to the problems of fouled and clogged gas ducts.
Patent PT-1487748-E (PT)
Title: Electrochemical process for decontamination of radioactive materials
Inventor: BRADBURY DAVID
IPC: G21F9/12
Filed: 2002-10-24
Abstract: A system for decontamination of radioactive components includes an acidic decontamination solution which is exposed to radioactive components to remove a layer of contaminated material and an ion exchange cell which removes the radioactive contamination from the decontamination solution. The ion exchange cell has cathode, anode and central compartments. The decontamination solution flows into the central compartment and the radioactive cations in the solution are drawn towards the cathode. The acidity in the cathode chamber is controlled so that small radioactive metal particles are deposited on the cathode. A cathode solution flows over the cathode which removes the deposited radioactive particles. The cathode solution and small particles flow into a waste collection container where the metal particles settle to the bottom of the container where they are easily separated from the solution. The only waste product produced by the system are the small radioactive metal particles which are easily disposed of. All liquids used in the decontamination process may be recycled.
Patent PT-1406040-E (PT)
Title: Base for an immersed motor agitator with rotor blades
Inventor: DIRLA MANFRED
IPC: F16F15/02
Filed: 1999-07-16
Abstract: The base structure (5) is intended for a stirring unit (4) with rotor blades and comprises a base section attached to the bottom of a basin (2), and a substantially vertical guide element (3). The element is made of a first material and has a sufficient height for fixing the stirring unit so that its rotor blades do not come into contact with the basin bottom. The base structure comprises at least one second material whose vibrational characteristics differ from those of the first material in such a way that vibrations induced by the stirring process are damped.
Patent PT-1461359-E (PT)
Title: Novel anti-igf-ir antibodies and uses thereof
Inventor: CORVAIA NATHALIE
IPC: G01N33/53
Filed: 2003-01-20
Abstract: An isolated antibody (Ab), and its functional fragments, that bind to human insulin-like growth factor-1 receptor (IGF-1R) and optionally: (i) inhibit natural binding of insulin-like growth factors (IGF)-1 and/or -2; and/or (ii) inhibit specifically tyrosine kinase activity of IGF-1R. An isolated antibody (Ab), and its functional fragments, that bind to human insulin-like growth factor-1 receptor (IGF-1R) and optionally inhibit natural binding of insulin-like growth factors (IGF)-1 and/or -2 and/or inhibit specifically tyrosine kinase activity of IGF-1R, is new. Ab comprises: (a) a light chain containing at least one complementarity-determining region (CDR) of one of 3 fully defined sequences comprising 16, 7 or 9 amino acids as given in the specification; or (b) a heavy chain containing at least one of the CDRs of one of 3 fully defined sequences comprising 6, 16 or 8 amino acids as given in the specification or sequences with 80% identity after optimal alignment. Independent claims are also included for the following: (1) murine hybridomas that secrete Ab; (2) an isolated nucleic acid (I) that: (a) is RNA or DNA and encodes Ab or its fragments; (b) is the complement of (a); or (c) has at least 18 nucleotides that can hybridize under stringent conditions with any of six sequences fully defined in the specification that encode the specified CDR, or with sequences having 80% identity after optimal alignment; (3) a vector containing (I); (4) a host cell containing the vector of (3); (5) a non-human transgenic animal containing at least one cell transfected with the vector of (3); (6) producing Ab or its fragments; (7) in vitro diagnosis of diseases induced by over- or under-expression of IGF-1R and or EGFR (epidermal growth factor receptor) by reaction with optionally labeled Ab; and (8) kit for performing method (7). ACTIVITY : Cytostatic; Antipsoriatic. The murine antibody 7C10, specific for IGF-1R, was tested (at 250 Microgram twice a week, intraperitoneally) against MCF-7 breast cancer cells, implanted in nude mice. After 37 days, the mean tumor volume was about 150 mm 3>; compared to about 800 mm 3> for controls and 300 mm 3> for animals treated with 10 Microgram tamoxifen. MECHANISM OF ACTION : Inhibition of signal transduction pathways mediated by IGF-1R, optionally also by epidermal growth factor (EGF) receptor, thus inhibiting growth and/or proliferation of tumor cells, especially where dependent on IGF, EGF, estrogens and/or HER2/neu.
Patent PT-1517862-E (PT)
Title: Method for treating an effluent in three biological steps
Inventor: KRIER JEAN
IPC: C02F3/12
Filed: 2003-06-11
Abstract: The invention concerns a method for biological treatment of an effluent in order to purify it comprising treating said effluent in a first step which consists in an anaerobic biological treatment ( 13 ), with sulphate-reducing biomass fixed on a mobile support ( 13 ), producing a first effluent, then treating the first effluent in a second which consists in an anoxic biological treatment ( 14 ), with stationary sulphur-oxidizing biomass ( 14 ), producing a second effluent, and finally treating the second effluent in a third step which consists in an aerobic biological treatment ( 15 ), with stationary nitrifying biomass, producing a third purified effluent. Said method further comprises recycling part of the effluent present in the third step to the second step. The biomass present in the first step comprises sulphate-reducing bacteria, the biomass present in the second step comprises sulphur-oxidizing bacteria and the biomass present in the third step comprises nitrifying bacteria. The invention also concerns a device for implementing said method.
Patent PT-1583748-E (PT)
Title: Process for the preparation of 1,2-dichloroethane free crystals of zonisamide and the highly pure crystals of zonisamide
Inventor: UENO YOSHIKAZU
IPC: A61P25/08
Filed: 2003-07-28
Abstract: A process for the preparation of crystals of zonisamide containing residual 1,2-dichloroethane of not more than 5 ppm, by adding an aqueous C<SUB>2-4 </SUB>alcohol to crystals of zonisamide containing residual 1,2-dichloroethane of more than 5 ppm, removing the 1,2-dichloroethane by azeotropic distillation, followed by collecting the precipitated crystals from the residual mixture.
Patent PT-1524678-E (PT)
Title: Electrolytic capacitors with polymeric outer layer
Inventor: JONAS FRIEDRICH
IPC: H01G9/028
Filed: 2004-10-05
Abstract: Solid electrolyte condensers with a dielectric-coated porous electrode, a solid electrolyte and a layer containing a polymeric anion plus a polyaniline or polythiophene, in which this outer layer also contains a binder. Electrolytic condensers containing a porous electrode, a dielectric on the surface of the electrode material, a solid electrolyte containing a conductive material covering some or all of the dielectric surface and a layer (A) on the covered parts containing polymeric anion(s) and optionally substituted polyaniline(s) and/or polythiophene(s) with repeating units of formula (I) and/or (II). Layer (A) also contains binder(s). [Image] A : optionally substituted 1-5C alkylene; R : 1-18C alkyl, 5-12C cycloalkyl, 6-14C aryl, 7-18C aralkyl or 1-4C hydroxyalkyl (all optionally substituted), or a hydroxyl group; x : 0-8. An independent claim is also included for a method for the production of electrolytic condensers in which a solid electrolyte is obtained by coating the dielectric layer with precursors of conductive polymers, plus oxidising agents and optionally counter-ions (optionally in the form of solutions) and then polymerising by chemical oxidation at -10 to 250[deg]C, or by coating with precursors of conductive polymers plus counter-ions (optionally from solution) and then polymerising by electrochemical oxidation at -78 to 250[deg]C, after which the layer containing a polymeric anion, polymer(s) with units (I) and/or (II) and binder(s) is applied from a dispersion containing these components.
Patent PT-1701730-E (PT)
Title: Method and vaccine comprising copolymer 1 for treatment of psychiatric disorders
Inventor: EISENBACH-SCHWARTZ MICHAL
IPC: C07K/
Filed: 2004-12-09
Abstract: Copolymer 1, a Copolymer 1-related peptide, a Copolymer 1-related polypeptide, and T cells activated therewith are useful in methods and compositions for treatment of psychiatric disorders, diseases and conditions.
Patent PT-1820022-E (PT)
Title: Use of flow-cytometric analysis to optimize cell banking strategies for cho cells
Inventor: OTTO RALF
IPC: A01N1/02
Filed: 2005-11-07
Abstract: Production of biopharmaceuticals from CHO cells requires generation of master-, working- and post-production cell banks of high quality, partly under GMP conditions. An optimal cryopreservation strategy is needed for each new production cell line, particularly with regard to the desire to establish production processes that are completely devoid of serum or even any animal components and to ensure robust thaw performance for reliable production. Here we describe a novel strategy employing flow cytometric (FC) analysis of Annexin V-stained cells for high-throughput characterization of CHO cell banks. Our data show that this method enables evaluation of a cryopreservation procedure just 6 h after thaw.
Patent PT-2032299-E (PT)
Title: Device for vacuum tight soldering an evacuated flat panel solar collector
Inventor: BENVENUTI CRISTOFORO
IPC: B23K1/00
Filed: 2006-06-26
Abstract: Device for vacuum tight soldering together a perimeter metal coating (5) of a transparent wall (4) to a perimeter metal frame (3) of a holding structure (2) of an evacuated solar collector (1), in particular a flat solar collector, said collector comprising a joining ribbon (6), preferably a soft metal strip or ribbon, in particular a lead and/or copper strip or ribbon, which is adapted to vacuum tight seal the gap (7) between said transparent wall (4) and said metal frame (3) and which is adapted to be soldered, in particular soft soldered, to said perimeter metal frame (3) and said perimeter metal coating (5) of the transparent wall (4), said joining ribbon comprising a soldering alloy, said device comprising heating means (24) for heating: a first part (5A) of said transparent wall (4) comprising at least a portion of said perimeter metal coating (5), a second part (3A) of said holding structure (2) comprising at least a portion of said perimeter metal frame (3), and said joining ribbon (6) to at least the melting temperature of said soldering alloy, when said transparent wall (4) is positioned in said holding structure (2) with said joining ribbon (6) overlapping at least partially said perimeter metal frame (3) and said metal coating (5), and pressure means (25) for applying at least on said first (5A) and second (3A) parts and said joining ribbon (6) a force which guarantees a mechanical contact of the melted soldering alloy to said metal frames (3) and said metal coating (5) throughout the solidification process of said soldering alloy.
Patent PT-2207809-E (PT)
Title: Heparin-binding epidermal growth factor-like growth factor antigen binding proteins
Inventor: ROTHE MIKE
IPC: A61K33/24
Filed: 2008-09-26
Abstract: Provided herein are antigen binding proteins, e.g., human and/or monoclonal antibodies that have affinity for heparin-binding epidermal growth factor-like growth factor (HB-EGF) and neutralize the biological functions of this growth factor.
Patent PT-711163-E (PT)
Inventor: CIOLI VALERIO
IPC: A61K31/415
Filed: 1994-07-14
Abstract: Use of benzydamine and physiologically acceptable acid addition salts thereof for preparing a medicament for the treatment of pathological conditions caused by TNF.
Patent PT-812205-E (PT)
Inventor: SCOTT KLEIN I
IPC: C07K5/072
Filed: 1994-10-17
Abstract: PCT No. PCT/US94/12135 Sec. 371 Date May 2, 1996 Sec. 102(e) Date May 2, 1996 PCT Filed Oct. 17, 1994 PCT Pub. No. WO95/10295 PCT Pub. Date Apr. 20, 1995The present invention relates to azacycloalkylalkanoyl peptides and pseudopeptides which inhibit platelet aggregation and thrombus formation thereby being useful in the prevention and treatment of thrombosis associated with disease states such as myocardial infarction, stroke, peripheral arterial disease, and disseminated intravascular coagulation, to methods for the prevention or treatment of thrombosis in a mammal in need of such therapy comprising the administration of a therapeutically effective amount of such compounds, and to pharmaceutical compositions comprising such compounds.
Patent PT-812190-E (PT)
Inventor: LEVY RUTH
IPC: A61P25/30
Filed: 1994-10-12
Abstract: The subject invention provides R(+)-N-propargyl-1-aminoindan and pharmaceutically acceptable salts thereof, as well as pharmaceutical compositions containing same. The subject invention also provides methods of treating a subject afflicted with Parkinson's disease, a memory disorder, dementia, depression, hyperactive syndrome, an affective illness, a neurodegenerative disease, a neurotoxic injury, brain ischemia, a head trauma injury, a spinal trauma injury, schizophrenia, an attention deficit disorder, multiple sclerosis, or withdrawal symptoms, using R(+)-N-propargyl-1-aminoindan or the pharmaceutically acceptable salt of the subject invention. The subject invention further provides a method of preventing nerve damage in a subject. Finally, the subject invention provides methods of preparing R(+)-N-propargyl-1-aminoindan, a salt thereof, and racemic N-propargyl-1-aminoindan.
Patent PT-766668-E (PT)
Inventor: HENTON DANIEL R
IPC: A61K/
Filed: 1995-04-28
Abstract: The present invention is related to novel processes for preparing anhydrous and hydrated forms of piperidine derivatives, polymorphs and pseudomorphs thereof of the formulas   
which are useful as antihistamines, antiallergic agents and bronchodilators.
Patent PT-833158-E (PT)
Inventor: PRIOR MICHAEL EVANS
IPC: G01N33/558
Filed: 1996-09-27
Abstract: A process of manufacturing test strips of the type comprising a length of porous carrier material capable of acting as a liquid flow path for a sample liquid and having at least zone downstream from a first end of the strip which zone contains an immobilised specific binding agent to act as a capture means during an assay to reveal the presence of an analyte in applied sample liquid, and in which process the specific binding agent is deposited onto a sheet of the porous carrier material which is then blocked and subdivided into a plurality of individual identical test strips, wherein blocking of the porous carrier material is achieved by applying a solution of blocking agent to the sheet upstream from the zone in an amount sufficient to ensure that the solution permeates downstream to beyond the zone. Preferably there is a plurality of zones of immobilised agent arranged in series on the strip, and wherein blocking is achieved by applying a solution of blocking agent to the sheet upstream from the first of the plurality of zones in an amount sufficient to ensure that the solution permeats downstream to beyond the last of the plurality of zones. <IMAGE>