baber/WOPTO huggingface dataset:
Patent AU-2018200587-A1 (AU)
Title: Fusion proteins comprising an engineered knottin peptide and uses thereof
Inventor: COCHRAN JENNIFER R
IPC: C12P21/04
Filed: 2018-01-24
Abstract: FUSION PROTEINS COMPRISING AN ENGINEERED KNOTTIN PEPTIDE AND USES THEREOF The present disclosure presents a general approach to engineering existing protein-protein interactions through domain addition and evolution. The disclosure teaches the creation of novel fusion proteins that include knottin peptides where a portion of the knottin peptide is replaced with a sequence that has been created for binding to a particular target. Such fusion proteins can also be bispecific or multi specific in that they can bind to and/or inhibit two or more receptors or receptor ligands. Knottins may be fused with an existing ligand (or receptor) as a general platform for increasing the affinity of a ligand-receptor interaction or for creating a multi specific protein. In addition, the fusion proteins may comprise a knottin peptide fused to another protein where the other protein facilitates proper expression and folding of the knottin.
Patent AU-2018202274-A1 (AU)
Title: Method for packaging fungal spores in a modified atmosphere with a view to increasing the shelf life of the fungi
Inventor: RODRIGUES DE FARIA MARCOS
IPC: C12Q3/00
Filed: 2018-03-29
Abstract: Patent of Invention: Title "METHOD FOR PACKAGING FUNGAL SPORES IN A MODIFIED ATMOSPHERE WITH A VIEW TO INCREASING THE SHELF LIFE OF THE FUNGI". The present invention relates to a packaging method for increasing the shelf life of fungal spores and to the packaging that contains such spores. The packaging method comprises the steps of pre-drying the spores to a water activity range viable for the fungus of interest, followed by packing of the spores into gas- and water-vapour impermeable packaging by means of the use of sachets, thereby providing an atmosphere of low relative humidity and low oxygen content, followed by keeping of the spores in the packaging for a certain period of time at the temperature suitable for the spores prior to the exposure thereof to high temperatures.
Patent AU-2018202424-A1 (AU)
Title: Method and apparatus for testing swellable materials
Inventor: NUTLEY KIM
IPC: G01N27/12
Filed: 2018-04-06
Abstract: METHOD AND APPARATUS FOR TESTING SWELLABLE MATERIALS The invention provides a method and apparatus (50) for use in testing the swell characteristics of swellable components (34) used in downhole exploration or production equipment, such as swellable packers. A method of measuring a test piece (30) using a testing apparatus with a fluid chamber (54) and a transducer (70) is described. Measured data can be compared with data measured from a sample section of a tool to determine a relationship between swell characteristics. The determined relationships can then be used to calculate or predict swelling characteristics of swellable components, for example particular packer designs, in specific fluid samples.
Patent AU-2018203038-A1 (AU)
Title: Systems and methods for managing money from multiple players
Inventor: MILLER KENNETH L
IPC: A63F9/00
Filed: 2018-05-01
Abstract: Various embodiments that may generally relate to one or more games at one or more venues. Gaming at a venue may qualify a player for a bonus game. A pool from which awards are paid for winning the bonus game may be funded through gaming activity that is not at the one or more venues.
Patent AU-2018208656-A1 (AU)
Title: Nanopore detection of target polynucleotides from sample background
Inventor: MORIN TREVOR J
IPC: C12Q1/68
Filed: 2018-07-24
Abstract: Disclosed herein are methods and compositions for detection of target polynucleotides in a mixed sample by amplification of the target polynucleotide and detection in a nanopore device.
Patent AU-2018214037-A1 (AU)
Title: Method for modulating galactosylation of recombinant protein through optimization of culture medium
Inventor: JUNG JUN
IPC: C07K16/18
Filed: 2018-08-08
Abstract: Disclosed are a method for preparing a target recombinant protein with modulated galactosylation or a method for modulating the galactosylation of a target recombinant protein, including increasing the osmolality of a culture solution of animal cells which express a target recombinant protein during the animal cell culture; a method for preparing a target recombinant protein with modulated galactosylation or a method for modulating the galactosylation of a target recombinant protein, including supplementing asparagine to a culture solution of animal cells which express a target recombinant protein during the animal cell culture; a method for preparing a target recombinant protein with modulated galactosylation or a method for modulating the galactosylation of a target recombinant protein, including increasing the osmolality of an animal cell culture which expresses a target recombinant protein and supplementing asparagine thereto during the animal cell culture; and a target recombinant protein with modulated galactosylation, which is prepared by the method.
Patent AU-2018219637-A1 (AU)
Title: Tumor-treating pharmaceutical composition
Inventor: OZAWA YOICHI
IPC: A61K31/47
Filed: 2018-02-06
Abstract: Provided is a tumor-treating pharmaceutical composition used in combination therapy of lenvatinib and (6S,9aS)-N-benzyl-8-({6-[3-(4-ethylpiperazin-1-yl)azetidin-1-yl]pyridin-2-yl}methyl)-6-(2-fluoro-4-hydroxybenzyl)-4,7-dioxo-2-(prop-2-en-1-yl)hexahydro-2H-pyrazino[2,1-c][1,2,4]triazin-1(6H)-carboxamide.
Patent AU-2018246761-A1 (AU)
Title: System and method for demodulation reference signal overhead reduction
Inventor: XIA PENGFEI
IPC: H04W72/04
Filed: 2018-03-22
Abstract: An embodiment method defines a demodulation reference signal (DMRS) pattern for transmitting DMRSs for rank 3 or rank 4 transmissions. The DMRS pattern specifies 12 REs in total per physical resource block (PRB) for carrying DMRSs on three or four antenna ports in antenna ports 7-14 for rank 3 or rank 4 transmissions. DMRS settings for transmitting DMRS according to the DMRS pattern may be specified using a downlink control information table.
Patent AU-2018251094-A1 (AU)
Title: Compositions and methods that attenuate cognitive aging in individuals who do not have dementia
Inventor: RIEKER CLAUS
IPC: A61K31/202
Filed: 2018-04-05
Abstract: A method of attenuating, treating or preventing cognitive aging in an individual who does not have dementia includes administering to the individual a therapeutically effective amount of a composition containing an omega-3 fatty acid, a nitric oxide releasing compound, Vitamin B12 and choline. The composition is administered in a daily dose that provides 0.1 to 50 times the recommended daily requirement (RDA) of Vitamin B12 per day, more preferably 0.1 to 40 times the recommended daily requirement (RDA) of Vitamin B12 per day and 0.01 to 10.0 times the recommended daily requirement (RDA) of choline. Optionally Vitamin B6 and/or Vitamin B9 can be included in the composition. The method can achieve a benefit that is one or more of decreasing brain atrophy, increasing or maintaining number of synapses, increasing amyloid-β phagocytosis, or decreasing or maintaining neuro inflammation in the non-demented individual. The method can prevent dementia in an individual at risk thereof, for example an elderly human.
Patent AU-2018276345-A1 (AU)
Title: Treatment method
Inventor: SARO JOSE
IPC: A61K39/395
Filed: 2018-05-29
Abstract: The present invention relates to the treatment of cancer, in particular to the prevention of adverse effects caused by the administration of CD3 antibodies in the course of said treatment.
Patent AU-2018288933-A1 (AU)
Title: Method for preparing intermediate of 4-methoxypyrrole derivative
Inventor: SHIN JEONG-TAEK
IPC: A61K31/4015
Filed: 2018-06-21
Abstract: The present invention relates to a.method for preparing intermediates of 4- methoxypyrrole derivatives. The preparation method according to the present invention has advantages that the production cost can be lowered by using inexpensive starting materials, a high-temperature reaction is not required as a whole, inexpensive and non-explosive reagents are used instead of (trimethylsilyl)diazomethane, and further an intermediate of 4-methoxypyrrole derivatives can be prepared as a whole at a high yield.
Patent AU-2018328759-A1 (AU)
Title: A drilling mud management system and method
Inventor: HAVENGA FRANS CHRISTIAAN
IPC: E21B49/08
Filed: 2018-09-10
Abstract: An automated batch sampling drilling mud management system (1) includes a a portable mud measurement system (10) and a communications system (120). The portable mud measurement system (10) has one or more measurement devices (14) arranged to measure at least one property and/or characteristic of drilling mud; and a pumping system (16) arranged to pump a batch sample of drilling mud from a supply of drilling mud to the one or more measurement devices. The pumping system (16) is also able to subsequently flush the batch sample of drilling mud from the one or more measurement devices (14). The communications system (120) enables bidirectional communications between the mud management system (10) and a remote location to enable transfer of data therebetween and the exertion of control from the remote location to the mud management system (10).
Patent AU-2018345769-A1 (AU)
Title: Earth-boring tools and related methods
Inventor: RUSSELL STEVEN CRAIG
IPC: E21B10/54
Filed: 2018-10-02
Abstract: An earth-boring tool comprising a body having first cutting elements mounted to an axially leading face, the first cutting elements each having a cutting face exposed to a height above the face of the body, the cutting faces of the first cutting elements back raked and facing a direction of intended rotation of the earth-boring tool. The earth-bring tool further comprises second cutting elements mounted to the axially leading face of the body adjacent first cutting elements in a cone region of the bit face, the second cutting elements each having a cutting face exposed to a height above the face of the body and configured for a shear-type cutting action, the cutting faces of the second cutting elements back raked to about a same or greater extent than the first cutting elements and generally facing the direction of intended rotation of the earth-boring tool.
Patent AU-2018364114-A1 (AU)
Title: Conjugates of biomolecule and use thereof
Inventor: LIU YUAN
IPC: A61K47/60
Filed: 2018-11-07
Abstract: Provided are conjugates of biomolecule and use thereof. The provided conjugates of biomoelculer contain a biomolecule and a functional moiety covalently linked to the biomolecule. The functional moiety contains a group that prevents the biomolecule from binding to its ligand or receptor, a cleavable linker arm that can be activated by proteolytic enzymes or can be acidically activated in a microenvironment of a disease, a linker arm that will automatically shed after the cleavable linker arm is cleaved, and a group that maintains or promotes the binding capacity of the biomolecule to its ligand or receptor. The conjugates of biomolecule can effectively reduce immunogenicity of the biomolecule, increase it's half-life, and breakthrough the immune barrier of an individual, reach a pathologic microenvironment and be activated and released in the pathologic microenvironment, selectively promoting proliferation or killing effect of T cells and the like in the tumor, thereby preventing on target off tumor toxicity or in the inflammatory microenvironment of autoimmune disease and achieving a low autoimmunity and high efficacy.
Patent AU-2018367450-A1 (AU)
Title: Metal level overshoot or undershoot mitigation at transition of flow rate demand
Inventor: SINDEN AARON DAVID
IPC: B22D11/20
Filed: 2018-11-14
Abstract: Automated processes and systems dynamically control the delivery rate of molten metal to a mold during a casting process. Such automated processes and systems can include automatically controlling a flow control device(such as a control pin) during a first phase of casting to modulate molten metal flow or flow rate, moving the flow control device in a transition time between the first phase and a second phase toward a substitute flow control device position determined based on a difference between a first projected flow rate of the first phase and a second projected flow rate of the second phase, and resuming automatic control of the flow control device during the second phase based on the detected metal level and the metal level setpoint. Overshoot and/or undershoot can additionally or alternatively be mitigated by translating the mold or altering the cast speed.
Patent AU-2018383023-A1 (AU)
Title: Dual detector with transverse coils
Inventor: MANNESCHI ALESSANDRO
IPC: H04B5/00
Filed: 2018-12-14
Abstract: The invention relates to a dual detector comprising a detection head (10) having: - a platform (11), and - an inductive sensor which is mounted on the platform (11) and includes a transmitter coil (12) and a separate receiver coil (13), the transmitter coil (12) and the receiver coil (13) each forming a loop, the loop of the transmitter coil (12) at least partially overlapping the loop of the receiver coil (13) so as to form a coupling region (14) which is elongate in a first longitudinal direction defining a first axis (X
Patent AU-2018388451-A1 (AU)
Title: System and method of floating point multiply operation processing
Inventor: DANYSH ALBERT
IPC: G06F7/523
Filed: 2018-12-11
Abstract: A processor includes an integer multiplier configured to execute an integer multiply instruction to multiply significand bits of at least one floating point operand of a floating point multiply operation. The processor also includes a floating point multiplier configured to execute a special purpose floating point multiply accumulate instruction with respect to an intermediate result of the floating point multiply operation and the at least one floating point operand to generate a final floating point multiplication result.
Patent WO-2019153033-A1 (WO)
Title: Silver fluoride solutions for dental compositions
Inventor: FARRAR PAUL
IPC: A61P31/04
Filed: 2019-02-07
Abstract: The present invention relates to an aqueous Silver Fluoride (AgF) containing solutions with pH 4.0 - 5.3.
Patent WO-2020097668-A1 (WO)
Inventor: HAMILTON ANDREW GRAHAM
IPC: B03B9/00
Filed: 2019-08-16
Abstract: An apparatus for processing magnetite iron ore, including a screen arranged to send oversize material to a regrind mill and undersize material to a high grade concentrate thickener and includes a CCD thickener type system for product grade improvements.
Patent AU-2019200990-A1 (AU)
Title: Picture decoding device, picture decoding method and picture decoding progam
Inventor: NAKAMURA HIROYA
IPC: H04N19/463
Filed: 2019-02-13
Abstract: In a picture coding device for coding picture signals including a brightness signal and a color-difference signal in a block unit using intra-prediction and coding information regarding an intra-prediction mode, when aspect ratios of pixels of the brightness signal and the color-difference signal are different from each other, a bitstream generator 113 converts a mode number of a first intra-color-difference prediction mode used when the aspect ratios are equal to each other into a scaled mode number and derives a second intra-color-difference prediction mode used when the aspect ratios are different from each other.
Patent AU-2019201853-A1 (AU)
Title: User interface for managing controllable external devices
Inventor: COFFMAN PATRICK L
IPC: H04L12/26
Filed: 2019-03-18
Abstract: An electronic device, with a display, a touch-sensitive surface, one or more processors, and memory, displays, on a first user interface screen, an indication of a location. The device displays, on the first user interface screen, a representation of a controllable external device at the location. The device detects a first user input corresponding to selection of the controllable external device, and in response to detecting the first user input, displays a user interface object indicating a plurality of possible states of the controllable external device. While displaying the user interface object indicating the plurality of possible states of the controllable external device, the device detects a second user input corresponding to selection of a designated state of the controllable external device. In response to detecting the second user input, the device sends instructions to set the controllable external device to the designated state.
Patent AU-2019204100-A1 (AU)
Title: Systems for treating pulmonary infections
Inventor: PERKINS WALTER
IPC: A61P11/00
Filed: 2019-06-12
Abstract: SYSTEMS FOR TREATING PULMONARY INFECTIONS Provided herein are systems for treating a subject with a pulmonary infection, for example, a nontuberculous mycobacterial pulmonary infection, a Burkholderia pulmonary infection, a pulmonary infection associated with bronchiectasis, or a Pseudomonas pulmonary infection. The system includes a pharmaceutical formulation comprising a liposomal aminoglycoside dispersion, and the lipid component of the liposomes consist essentially of electrically neutral lipids. The system also includes a nebulizer which generates an aerosol of the pharmaceutical formulation at a rate greater than about 0.53 gram per minute. The aerosol is delivered to the subject via inhalation for the treatment of the pulmonary infection.
Patent AU-2019211239-A1 (AU)
Title: Website creation system for creating websites having at least one series of directional webpages and related methods
Inventor: DICKERSON TODD
IPC: G06F16/957
Filed: 2019-01-22
Abstract: The present disclosure is directed towards systems and methods for creating a website and response actions via a website creation system. The systems and methods provide a plurality of website types for selection, and in response to receiving a selection of a website type, provide a plurality website templates specific to the selected website type. Each website type may include a series of directional webpages designed and intended to entice a particular user interaction with the website. Additionally, the systems and methods receiving a selection of a type of response action, a selection of at least one rule of a triggering condition, and an operand for the at least one rule of the triggering condition. Moreover, in response to the event of the triggering condition, the systems and method perform the response action.
Patent AU-2019229468-A1 (AU)
Title: Electronic device for determining an emergency stopping trajectory of an autonomous vehicle, related vehicle and method
Inventor: LE CORNEC OLIVIER
IPC: G05D1/02
Filed: 2019-09-16
Abstract: 5 Electronic device for determining an emergency stopping trajectory of an autonomous vehicle, related vehicle and method This device is able to be activated automatically in the presence of an emergency stopping instruction, and comprises: 10 - a module for calculating at least one automatic movement setpoint of the vehicle in order to follow an emergency stopping trajectory comprising a plurality of successive emergency stopping vectors each associated with a separate segment of a portion of the successive segments of the predefined trajectory, from at least for each emergency stopping vector: 15 o a stored last actual movement vector of the autonomous vehicle, o the predefined movement trajectory of the autonomous vehicle, and o a stored last location datum of the autonomous vehicle, and delivered by at least one sensor of the autonomous vehicle, - an emergency steering module capable of steering the vehicle according to said at least 20 one setpoint. Figure 2 VIDf 46 44 vi DET-CONS STOP S= </D-0 M-CONS -42 y ? ;-LOS 36 POS-A
Patent AU-2019247818-A1 (AU)
Title: Controlled release of radionuclides
Inventor: KELSON ITZHAK
IPC: C23C14/48
Filed: 2019-03-28
Abstract: A brachytherapy device (20, 21) including a base (22) adapted for being at least partially introduced into a body of a subject and a plurality of radionuclide atoms of a first alpha-emitting isotope, coupled to the base in a manner that not more than 15% of the radionuclide atoms leave the base in 24 hours, in methods other than radioactive decay. When installed in a human subject, the brachytherapy device emits radionuclide atoms of the first alpha-emitting isotope at a rate of at least 0.1% of the number of radionuclide atoms of the first alpha-emitting isotope coupled to the base, per 24 hours.
Patent AU-2019261771-A1 (AU)
Title: Inhibitors of lysine specific demethylase-1
Inventor: CHEN YOUNG K
IPC: C07D401/14
Filed: 2019-11-07
Abstract: INHIBITORS OF LYSINE SPECIFIC DEMETHYLASE-1 The present invention relates generally to compositions and methods for treating cancer and neoplastic disease. Provided herein are substituted heterocyclic derivative compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for inhibition of lysine specific demethylase-1. Furthermore, the subject compounds and compositions are useful for the treatment of cancer, such as prostate cancer, breast cancer, bladder cancer, lung cancer and/or melanoma and the like.
Patent AU-2019266407-A1 (AU)
Title: Automated dental drill
Inventor: CIRIELLO CHRISTOPHER JOHN
IPC: A61B34/20
Filed: 2019-05-09
Abstract: An automated dental drill includes a dental drill housing that includes a mouth piece housing section and a one or more degrees of freedom drive housing section; an end effector drive support having a shaft section that is at least partially positioned in the mouth piece housing section, and an end effector for the cutting of a native tooth or dental appliance to a desired tolerance. The end effector is positioned on the end effector drive support. The automated dental drill also includes a power source that drives the end effector and is coupled to the end effector and a one or more degrees of freedom drive assembly to direct the end effector along one or more degrees of freedom relative to the mouth piece housing section.
Patent AU-2019271028-A1 (AU)
Title: Chemical compositions and methods of using same
Inventor: DUNAWAY DWAYNE
IPC: C12Q1/6869
Filed: 2019-05-14
Abstract: The present disclosure relates to chemical compositions, kits, and apparatuses and methods for using these compositions, kits and apparatuses in various assays.
Patent AU-2019281200-A1 (AU)
Title: Electrochemical sensor
Inventor: PILETSKY SERGEY
IPC: G01N27/327
Filed: 2019-06-05
Abstract: An electrochemical sensor comprising first and second electrodes. The first electrode has a molecular imprinted polymer (MIP) immobilised thereon and the MIP comprises a redox label and is imprinted with an analyte. The disclosure also provides methods of producing such sensors, methods of detecting and determining the concentration of analytes and the use of the electrochemical sensors for the detection of analytes.
Patent AU-2019289248-A1 (AU)
Title: High spectral efficiency “Zero Bandwidth Modulation Process” without side bands
Inventor: AGGARWAL RAKESH
IPC: H04B1/02
Filed: 2019-06-17
Abstract: A method (1000) for transmission of signal, comprises the steps of receiving (1020) one or more modulating signals having features selected from a group comprising one or more amplitudes, one or more frequencies, one or more phase angles, one or more time periods and combinations thereof, generating (1040) one or more sinusoidal carrier waves, including one or more wave cycles that have a predetermined one or more properties, at one or more zero voltage crossing points in accordance with the one or more values of the one or more modulating signals. The one or more properties of each of the one or more wave cycles of the one or more sinusoidal carrier waves is configured to change in proportion to one or more values of the one or more modulating signals only after completion of each of the one or more wave cycles.
Patent AU-2019325411-A1 (AU)
Title: Devices, systems, and methods for remotely monitoring and treating wounds or wound infections
Inventor: BOGIE KATH M
IPC: A61N1/372
Filed: 2019-08-23
Abstract: Devices and methods for remotely monitoring and treating wounds or wound infections are disclosed. Systems including the described devices are also disclosed.