baber/WOPTO huggingface dataset:
Patent CA-2249320-A1 (CA)
Title: Glycosylated humanized b-cell specific antibodies
Inventor: QU ZHENGXING
IPC: A61K38/00
Filed: 1997-03-19
Abstract: A humanized specific monoclonal antibody or antibody fragment, especially a B-cell specific antibody or antibody fragment, is engineered to contain a glyxosylation site in the non-Fc constant region. The glycosylated antibody is useful for diagnosis and/or therapy whenever a targeting antibody or fragment is used, especially for B-cell malignancies. The carbohydrate moiety allows conjugation of labeling or therapeutic agents of increased size, without affecting the binding affinity or specificity of the antibody.
Patent CA-2250418-A1 (CA)
Inventor: DRANE MARK R
IPC: F16L55/035
Filed: 1998-10-13
Abstract: An assembly for supporting a pipe to a structural channel includes a pipe cushion having a deformable pipe cushion body and a base for positioning on the structured channel. The base includes a slot therethrough. The body includes a continuous tubular wall extending from the base and is divided by the slot. The tubular wall forms a pipe supporting passageway through the body. The slot is in communication with the passageway and permits insertion of the pipe therein. The assembly also includes a pair of pipe clamp elements. The pipe clamp elements have a first end attachable to the channel and a second end for mutual connection to each other about the pipe cushion. The second ends of the pipe clamp elements are connectable at a crest of the body spaced from the slot.
Patent CA-2256178-A1 (CA)
Title: Postage metering system and method for a stand-alone meter operating as a meter server on a network
Inventor: PIERCE PERRY A
IPC: B65G61/00
Filed: 1998-12-16
Abstract: A postage metering system includes a plurality of printer modules operatively connected as part of a network and operating as client printer modules on the network. A postal security device (PSD) is coupled directly to a local one of the client printer modules. The PSD includes unique identification, postal value storage and a digital signature generator. The client printer modules function as a postage metering network wherein a one of the client printer modules remote to the PSD requests evidence of postage payment from the PSD through the local client printer module for concluding postage metering transactions. The local client printer module function as a stand-alone meter when requests for evidence of postage payment from the PSD are initiated at the local client printer module. The local client printer module initiates local requests for evidence of postage payment to be printed at the local client printer modules and receives remote requests for evidence of postage payment from the remote client printer modules. The remote requests include identification of the remote client printer modules. The local client printer module sends each request for evidence of postage payment to the PSD and receives from the PSD the evidence of postage payment including a digital signature corresponding to each request for evidence of postage payment;. The local client printer module sends the evidence of postage payment to the remote client printer modules in response to the remote request, and prints the evidence of postage payment in response to the local request.
Patent CA-2256951-A1 (CA)
Inventor: FORTIER DAVID R
IPC: B01D17/032
Filed: 1998-12-23
Abstract: An apparatus 46 for receiving metalworking fluid from a sump 12 of a machine 10 is disclosed. Various construction details are developed which provide for the collection of fluid and increasing the concentration of tramp oil in the collected fluid. In one embodiment of the invention, the apparatus includes a colllection chamber 48 having an interior 54 which is in flow communication through an opening 58 in a wall 56 of the chamber with the top most layer of the metalworking fluid.
Patent CA-2258559-A1 (CA)
Title: Indoline derivatives useful as 5-ht-2c receptor antagonists
Inventor: BROMIDGE STEVEN MARK
IPC: C07D401/14
Filed: 1997-06-16
Abstract: The invention relates to heterocyclic compounds of formula (I) or a salt thereof wherein R1 is hydrogen or C1-6 alkyl; R2, R3 and R4 groups are independently hydrogen, halogen or C1-6 alkyl optionally substituted by one or more fluorine atoms, having pharmacological activity, processes for their preparation, to compositions conta ining them and to their use in the treatment of CNS disorders such as anxiety.
Patent CA-2258758-A1 (CA)
Inventor: SYMONS MICHAEL WINDSOR
IPC: C08L97/02
Filed: 1997-06-26
Abstract: A method of making a composite product, such as a basin or a tile, includes the steps of impregnating particles of an exfoliated vermiculite or a lignocellulosic material with an impregnating composition comprising a first thermosetting resin, an extending liquid for the thermosetting resin, if necessary a catalyst for the thermosetting resin and a colouring agent for the particles; removing the extending liquid; subjecting the impregnated particles to suitable conditions, generally of temperature and for pressure, to polymerise or cross-link the first thermosetting resin; coating the particles so produced with a binder composition comprising a second thermosetting resin and if necessary a catalyst for the second thermosetting resin; forming the particles into a desired shape, either in a mould or on a plate of a press;  and subjecting the particles to suitable conditions to polymerise, condense or cross-link the second thermosetting resin to bind the particles together to form the composite product.
Patent CA-2261057-A1 (CA)
Title: Synthesis of polyol fatty acid polyesters using column with inert gas stripping
Inventor: GRANBERG ERIC PAUL
IPC: C07H13/06
Filed: 1997-07-16
Abstract: Processes for the synthesis of polyol fatty acid polyester by transesterifiataion of a polyol comprise reacting polyol with a first portion of fatty acid lower alkyl ester to provide a first step reaction product in which substantially all of the polyol is reacted with at least one fatty acid lower alkyl ester. The processes then employ a multistage column providing substantial plug flow of liquid therein for further transesterification of the first step reaction product. Partially esterified polyol, a second portion of fatty acid lower alkyl ester and catalyst are fed to the column to form a mixture and cause further transesterification of the partially esterified polyol and fatty acid lower alkyl ester, with lower alkylalcohol being formed as a by-product. The resulting liquid mixture of reactants and product is passed in a first direction between adjacent stages through the column for further reaction of partially esterified polyol with fatty acid lower alkyl ester. An inert stripping or sparging gas is fed through the column in a second direction between adjacent stages, counter current to the flow of the liquid mixture between adjacent stages in the first direction, with radial shear agitation. The lower alkyl alcohol by-product of the polyol-fatty acid lower alkyl ester reaction is transferred from the liquid mixture to the inert gas.
Patent CA-2261596-A1 (CA)
Title: Opposed piston combustion engine
Inventor: HOWELL-SMITH BRADLEY DAVID
IPC: F01B9/02
Filed: 1996-07-17
Abstract: An engine (1) comprises two counter rotating multilobate cams (8, 9) which are acted upon by a pair of diametrically opposed pistons (4, 5) which are rigidly interlinked by connecting rods (6a, 6b). Differential gearing is provided to time the counter rotation of the cams (8, 9).
Patent CA-2263340-A1 (CA)
Inventor: YUAN JUN
IPC: C07D209/88
Filed: 1997-08-12
Abstract: L'invention concerne des composés utiles pour le tratiemetn de troubles affectifs, (schizophrénie, dépression, maladie d'Alzheimer, par exemple), troubles de la fonction motrice (parkinsonisme ou dystonie, par exemple) ou d'autres troubles qui réagissent au blocage dopaminergique comme l'abus d'intoxicants ou les troubles obsessivo-compulsifs. Les composés de l'invention sont en outre utiles pour le traitement des effets secondaires extrapyramidaux associés à l'utilisation d'agents neuroleptiques classiques. Lesdits composés sont de la formule (I) and laquelle (a) représente un noyau aromatique ou alicyclique; R¿1? et R¿2? sont égaux ou différents et représentent hydrogène, alkyle C¿1?-C¿6?, halogène, hydroxy, amino, cyano, nitro, trifluorométhyle, trifluorométhoxy, alcoxy C¿1?-C¿6?, -O¿2?CR', -NHCOR', -COR', -SO¿m?R', R' étant alkyle C¿1?-C¿6?, m étant égal à 0, 1 ou 2; ou R¿1? et R¿2? représentent, indépendamment, -CONR'R'', ou -NR'R'', R' et R'' représentant indépendamment hydrogène ou alkyle C¿1?-C¿6?; R¿3? is hydrogène, alkyle C¿1?-C¿6?, ou -COR''', R''' étant alkyle C¿1?-C¿6?; R¿4? est hydrogène, alkyle C¿1?-C¿6?, et R répresente un groupe azacycloalkyalkyle.
Patent CA-2263403-A1 (CA)
Title: Transport container
Inventor: HALL DANIEL JOHN
IPC: B65D88/12
Filed: 1997-08-11
Abstract: A container (10) for use in the transportation of goods includes a floor (12) and a pair of opposed side walls (14, 16) each of which is supported for displacement about a pivotal axis adjacent its upper edge. The container (10) also includes hinge means (26) whereby one side wall (14) is disconnectably connectable adjacent its lower edge to the floor (12). The container (10) further includes first displacement means (52) for displacing the floor (12) laterally between a rest position in which goods can be contained within the container (10), and a displaced position. When the side wall (14) is connected to the floor (12). However, the floor (12) is displaced independently of the side wall (14) when the hinge means (26) is disconnected.
Patent CA-2264688-A1 (CA)
Title: Apparatus and methods for active biological sample preparation
Inventor: JACKSON THOMAS R
IPC: B01J19/00
Filed: 1997-07-31
Abstract: Systems and methods for the electronic sample preparation of biological materials utilize the differential charge-to-mass ratio and/or the differential affinity of sample constituents to separation materials for sample preparation. An integrated system is provided for performing some or all of the processes of: receipt of biological materials, cell selection, sample purification, sample concentration, buffer exchange, complexity reduction and/or diagnosis and analysis. In one embodiment, one or more sample chambers adapted to receive a buffer solution are formed adjacent to a spacer region which may include a trap or other affinity material, electrophoretic motion of the materials to be prepared being effected through operation of electrodes. In another aspect of this invention, a transporter or dipstick serves to collect and permit transport of materials, such as nucleic acids, most preferably DNA and/or RNA. In one embodiment, a membrane or trap is held in a frame which is adapted to mate with a channel formed in the spacer region. In another aspect of this invention, an electrophoretic system for biological sample preparation is operated in a manner so as to utilize the differential charge-to-mass ratio so as to control the migration of materials within the solution. In one aspect, bunching of selected materials is achieved by operation of two electrodes in a manner so as to reduce the spatial dispersion of those materials. In another aspect of this invention, a vertically disposed sample preparation unit includes an upper reservoir and a collection chamber. A sample is preferably pre-prepared and densified, applied to the conductive polymer, electrophoresed so as to move nucleic acids into the conductive polymer and move undesired material away from the conductive polymer. Integrated systems are described in which cell separation, purification, complexity reduction and diagnosis may be performed together. In the preferred embodiment, cell separation and sample purification are performed in a first region, the steps of denaturation, complexity reduction and diagnosis being performed in a second region.
Patent CA-2265140-A1 (CA)
Inventor: SAVOJI SEINA
IPC: F16B35/04
Filed: 1999-03-10
Abstract: An anti-cross threading fastener including a shaft portion having a first leading end portion with a first end, a first threaded shaft portion having a first tapered threaded shaft portion narrowing toward the first end, and screw threads of the first tapered threaded shaft portion have a flank angle greater than a flank angel of the screw threads of a first non-tapered threaded shaft portion.  The screw threads of the first tapered threaded shaft portion preferably have the same pitch as the screw threads of the first non-tapered threaded shaft portion.  A cylindrical shaft portion having a diameter less than a major diameter of the first threaded shaft portion may be disposed between the first end of the shaft portion and the first threaded shaft portion.  The first leading end portion may have a first tip portion with a partially substantially curved surface, or a driving tool engagement surface.
Patent CA-2265819-A1 (CA)
Inventor: PATTERSON HUBERT A
IPC: G08B13/24
Filed: 1997-09-26
Abstract: An apparatus for data communication and deactivating an electronic article surveillance tag comprising an antenna (54) for communicating with a transponder located within a predetermined area and a deactivation coil (52) for deactivating an electronic article surveillance tag located within the predetermined area.
Patent CA-2272613-A1 (CA)
Title: A flexible wideband architecture for use in radio communications systems
Inventor: BEXTEN RONALD L
IPC: H04L5/06
Filed: 1997-10-28
Abstract: A wideband digital architecture for use in radio communications systems. In an exemplary embodiment, a central hub station is coupled by high speed digital data transports to multiple distributed radio transceivers. The radio transceivers are designed to perform relatively little signal processing, while the central hub is designed to perform computationally intensive signal processing tasks. By exchanging wideband data between the radio transceivers and the hub, by centralizing key system resources at the hub, and by adaptively allocating the system resources in accordance with actual system usage, the radio architecture of the present invention maximizes overall system capacity, flexibility, and resource usage efficiency while minimizing overall system cost.
Patent CA-2272981-A1 (CA)
Inventor: SHELLENBERGER TIMOTHY J
IPC: F24H9/20
Filed: 1999-05-20
Abstract: A water heater heating element including a base member adapted to extend through and sealingly engage a wall of a water heater tank, the base member having a recess; a thermistor positioned in the recess; members connected to the thermistor and extending outwardly of the base member to transmit temperature information; a sheathing sealed to and extending outwardly from the base member; a heating coil positioned within the sheathing; cold pins connected to opposed ends of the heating coil and to the base member, the cold pins being sufficiently long that heat generated by the heating coil is not detected by the thermistor; and members connected to the cold pins and extending outwardly of the base member to transmit power to the heating coil.
Patent CA-2277503-A1 (CA)
Title: Method to render a hard surface hydro-philic
Inventor: SRAMEK JOHN A
IPC: C11D1/79
Filed: 1999-07-12
Abstract: A composition, that imparts or enhances hydrophilic properties to a surface on which the composition is applied, comprises i) an associative polymeric thickening agent; and ii) a compound represented by the chemical structure:   (see formula I) wherein Z = H, CH3, or C2H5; Y = H, CH3, or C2H5; M = 1 to 30;      N = 0 to 30; R1 = H, CH3, C2H5, a branched or unbranched C~-22 alkane or alkene substituent, or nothing; R2 = H, CH3, C2H5, a branched or unbranched C~-22, alkane ar alkene substituent, O, or nothing; X = N, O, S, P, Si, PO3, or SO3; and Y=R2 when N=0.
Patent CA-2277820-A1 (CA)
Inventor: WILLEY ALAN DAVID
IPC: D06L4/75
Filed: 1998-01-22
Abstract: The present invention relates to photochemical singlet oxygen generators having enhanced fabric substantivity, said photochemical singlet oxygen generators useful as photobleaches in laundry detergent compositions. The present invention is also directed to methods for removing stains on fabric by contacting dirty and stained fabric with the photobleaching agents described herein.
Patent CA-2281038-A1 (CA)
Title: Communication terminal apparatus, internet facsimile apparatus, and e-mail receiving method
Inventor: AKIMOTO MASAO
IPC: H04N1/00
Filed: 1999-08-30
Abstract: In an Internet facsimile apparatus, a mail header receiving section receives a list n-th mail header portion of e-mail. Next, a header analyzing section analyzes the mail header portion and checks whether or not the e-mail is fragments of the e-mail obtained by dividing the e-mail. A table generating section registers the fragments in processing into a table. Thereafter, the fetching determination; section checks whether or not the all fragments having the same ID are prepared. If all fragments are prepared, a data receiving section reads the fragments from a mail server sequentially from the first. Text codes of attached files included in the fragments are binary converted sequentially so as to be stored in a buffer section. A printing determination section instructs a print processing section to execute printing when there is image data corresponding to one page of an original in the buffer. This makes it possible to receive a division mail at low cost in the Internet facsimile apparatus.
Patent CA-2281695-A1 (CA)
Title: Process for the preparation of substituted thiazolidinedione
Inventor: MOORE STEPHEN
IPC: C07D417/12
Filed: 1998-02-13
Abstract: A process for preparing a compound of formula (I) or a tautomeric form thereof or a pharmaceutically acceptable salt thereof or a pharmaceutically acceptable solvate thereof, wherein: J represents O or S; T  represents a substituted or unsubstituted aryl group and T1 is O or S; which process comprises reducing a compound of formula (II) or a tautomeric form thereof or a salt thereof or a solvate thereof, wherein T and T1 are as defined in relation to formula (I), with a complex hydride reducing agent or a source of a complex hydride reducing agent; and thereafter, as required, preparing a pharmaceutically acceptable salt or a pharmaceutically acceptable solvate of the compound of formula (I) or a tautomeric form thereof.
Patent CA-2284779-A1 (CA)
Title: Controlled fluid transport in microfabricated polymeric substrates
Inventor: PARCE J WALLACE
IPC: B01L3/00
Filed: 1998-04-14
Abstract: Microfluidic devices (202) are provided for the performance of chemical and biochemical analyses, syntheses and detection (230). The devices of the invention combine precise fluidic control systems with microfabricated polymeric substrates to provide accurate, low cost miniaturized analytical devices that have broad applications in the fields of chemistry, biochemistry, biotechnology, molecular biology and numerous other fields.
Patent CA-2286328-A1 (CA)
Title: Noninvasive detection of colonic biomarkers using fecal messenger rna
Inventor: LUPTON JOANNE R
IPC: C12Q1/6883
Filed: 1998-04-03
Abstract: A noninvasive method utilizing feces, containing sloughed colonocytes, as a sensitive technique for detecting diagnostic colonic biomarkers. By incorporating the sensitivity of semi-quantitative RT-PCR, this novel method is capable of isolating and quantitating specific eukaryotic mRNAs as candidate biomarkers in feces. In particular, measurement of the relative expression of fecal PKC .beta.II and  serves as a biomarker for development of colon tumors.
Patent CA-2288536-A1 (CA)
Inventor: BROCK RONNIE J
IPC: A63B67/06
Filed: 1999-10-25
Abstract: A disc toss game, offering a game of skill and fun for all ages, indoors or outdoors. This game requires two to four players to toss a game disc into a cup inset on a rectangular game board. This inventive device includes a target board with three target cups and ten round discs (eight discs required to play and two spares) There are five black discs and five white discs. Each player is given four discs, choosing their own color. These discs are tossed by the player at the target board from a pre-determined distance so that the game discs may land in the target cups. Each cup is assigned a given amount of points: Cup #1 - 1 point, Cup #2 -3 points, Cup #3 - 5 points. The object of the game is to obtain a total assigned amount of points.
Patent CA-2294154-A1 (CA)
Title: Cd154 blockade therapy for pancreatic islet tissue transplantation
Inventor: THOMAS DAVID W
IPC: A61P3/10
Filed: 1998-06-19
Abstract: Methods and compositions for inhibiting rejection of insulin-producing tissue in a graft recipient, as well as methods and compositions for prolonging graft survival or function; for reversing graft rejection or restoring function of an impaired graft; and, for inducing immunological tolerance to grafted, insulin-producing tissue. The present methods and compositions are suitable for treatment or prophylaxis of defects in metabolic control of blood glucose homeostasis, including defects manifested as diabetes melitus (DM).
Patent CA-2294169-A1 (CA)
Title: Therapeutic method for management of diabetes mellitus
Inventor: RAMAMURTHY NUNGAVARAM S
IPC: A61K31/155
Filed: 1998-04-08
Abstract: A method for treating diabetes in a mammal by moderately controlling blood glucose concentration in the mammal together with administering to the mammal an amount of a tetracycline compound effective to reduce complications associated with diabetic hyperglycemia. The method enables long term management of diabetes by avoiding the problems associated with tight control of blood glucose concentrations, i.e., hypoglycemia tolerance and seizures, while simultaneously avoiding the problems associated with conventional moderate control of blood glucose concentrations, i.e., pathological complications associated with hyperglycemia, such as nephrophathy, retinopathy, etc. Blood glucose concentration can be controlled by moderate administration (e.g, fewer injections per day) of insulin or another glucose-modulating agent, while pathological complications characteristic of diabetic hyperglycemia are ameliorated through the activity of tetracycline compound, the latter preferably administered in an amount that is substantially non-antimicrobial.
Patent CA-2294316-A1 (CA)
Inventor: RISER ANDREW P
IPC: G02B6/42
Filed: 1998-02-18
Abstract: A light guide illumination system having a metal-halide double-ended illumination source is disclosed. The light guide illumination system includes at least one light guide (42, 28, 28a) and two curved reflectors (14) disposed in proximity to the double-ended illumination source. The two curved reflectors (14) are adapted to reflect the emitted light from the double-ended illumination source (12) into the light guide (42, 28, 28a). The light guide illumination system further includes at least one multi-sector lens (38) adapted to receive light from the light guide and at least one output light guide. The multi-sectored lens (38) is adapted to receive the reflected light from the light guide and to focus the light into the output light guide (40).