baber/WOPTO huggingface dataset:
Patent NZ-630826-A (NZ)
Title: Anti-egfr antibody drug conjugate formulations
Inventor: VINEET KUMAR
IPC: C07K16/28
Filed: 2014-03-14
Abstract: Discloses lyophilized pharmaceutical formualtions comprising an anti-EGFR antibody drug conjugate (ADC). The antibody has the HCDR sequences of SEQ ID NO: 15-17 and the LCDRs of SEQ ID NO: 20-22 or the HCVR of SEQ ID NO: 13 and the LCVR of SEQ ID NO: 18. The auristatin can be monomethylauristatin F (MMAF). The formulation further comprises a sugar, histidine and a surfactant. In a further embodiment the formulation comprises sucrose, histidine and polysorbate 80.
Patent NZ-707183-A (NZ)
Title: Child car seat having active protection means
Inventor: GARNIER NICOLAS
IPC: B60N2/427
Filed: 2013-10-25
Abstract: The invention concerns a child car seat, comprising active protection means and means for triggering the active protection means, in case of need. According to the invention, the triggering means deliver a command for triggering the active protection means according to a combination of at least two signals: - at least one first signal delivered by a piece of equipment of said seat, indicating a use of said seat in a vehicle, and - at least one second signal delivered by detection means, indicating the detection of an accident situation. The detection means includes mechanical means and electronic means, the mechanical means activating the electrical power supply of the electronic means when a force of inertia greater than a first acceleration threshold, called the waking threshold, is detected. The electronic means delivers the second signal when an acceleration force that is greater than a second threshold is detected, said second threshold being greater than the first threshold and corresponding to an accident situation.
Patent NZ-711009-A (NZ)
Title: Method and preparation system for preparing a brewed product
Inventor: DEUBER LOUIS
IPC: B65D85/804
Filed: 2013-04-03
Abstract: Disclosed is a coffee beverage brewing method to provide an improved brew flavour. The method comprises the steps of providing the capsule (1) as a closed capsule with a capsule wall, which has a covering surface on the extraction side and a covering surface on the injection side and a circumferential lateral surface extending between the extraction-side covering surface and the injection-side covering surface, introducing the capsule into a brewing module with an injector for introducing a brewing liquid into the capsule and a discharging device for discharging a brewed product, wherein the injector comprises at least one injection-side perforation element (12) and the discharging device comprises at least one extraction-side perforation element, closing a brewing chamber of the brewing module so that the at least one injection-side perforation element pierces the injection-side covering surface along a cutting line, introducing under pressure a brewing liquid into the region between the injection-side supporting surface and the injection-side covering surface, in such a manner that the pressure of the liquid causes the extraction-side covering surface to be displaced towards the interior of the capsule whilst an encompassing capsule seal (43) holds the circumferential lateral surface, and brewing liquid enters the capsule interior, and maintaining the pressure on the brewing liquid at least until the brewed product emerges from discharge openings produced in the extraction-side covering surface as a result of piercing by the at least one extraction-side perforation element.
Patent NZ-711398-A (NZ)
Title: Liquid containment system for use with load-supporting surfaces
Inventor: MCDOWELL JAMES KERWIN
IPC: E01H1/00
Filed: 2013-04-19
Abstract: System for containing liquid introduced onto a reusable load-supporting surface includes a plurality of interconnectable berm members configured to releasably sealingly engage the load-supporting surface to prevent leakage of liquid from the load-supporting surface around its perimeter without the use of any liners beneath the load-supporting surface. Temporary or semi-permanent support surfaces have been used for roadways, remote jobsites, industrial staging areas and the like in an ever-increasing myriad of industries, such as construction, military, oilfield, transportation, disaster response, utilities and entertainment.
Patent NZ-716275-A (NZ)
Title: An immunoglobulin fc conjugate which maintains binding affinity of immunoglobulin fc fragment to fcrn
Inventor: KWON SE CHANG
IPC: C07K19/00
Filed: 2014-07-14
Abstract: The present invention relates to a physiologically active polypeptide - immunoglobulin Fc fragment conjugate in which a physiologically active polypeptide is linked to an immunoglobulin Fc fragment including an FcRn binding region via a non-peptide linker, wherein the non-peptidyl linker is a polyethylene glycol polymer having a repeating unit of 10 to 480, is linked to the N-terminus of the immunoglobulin Fc fragment, and wherein the conjugate maintains the inherent binding strength of the immunoglobulin Fc fragment; a method for manufacturing the conjugate; a method for maintaining the inherent binding force of the conjugate to FcRn; and a composition comprising the conjugate and maintaining the inherent binding strength of the immunoglobulin Fc fragment to FcRn.
Patent NZ-717489-A (NZ)
Title: Production of galacto-oligosaccharides.
Inventor: BENJAMINS FRÉDÉRIC
IPC: C13K5/00
Filed: 2014-09-04
Abstract: The invention relates to the enzymatic preparation of galacto-oligosaccharides (GOS). Provided is a method for preparing GOS from lactose, comprising (i) contacting a lactose feed with immobilized beta- galactosidase (EC 3.2.1.23) and (ii) allowing for GOS synthesis, wherein said lactose feed is an aqueous slurry of crystalline lactose.
Patent NZ-719313-A (NZ)
Title: Interchangeable adapter for in-can and on-can fuel cells
Inventor: GIBSON ERIC S
IPC: F16L35/00
Filed: 2008-01-17
Abstract: An adapter 84 configured for use in combination with a cap or metering valve on a fuel cell having a closure formation, the cap having at least one leg portion and a corresponding foot extending from the leg comprising a ring portion 92 configured for engagement upon the closure formation of the fuel cell and including a top edge, a bottom edge, and a sidewall therebetween having an inner sidewall and an outer sidewall. The top edge defines at least one indentation constructed and arranged for receiving a corresponding projection of the cap or metering valve for properly aligning and securing the cap to the adapter. The projection is in vertical alignment with the cap or metering valve leg. The adapter further comprises a grooved portion defined by the inner sidewall, a convex gripping formation 106 on the outer sidewall complementary to the closure formation, and at least one recessed formation adjacent the grooved portion for receiving the foot.
Patent NZ-723674-A (NZ)
Title: A drilling jig device
Inventor: REELICK JOHANNES CANISIUS MARIE
IPC: E02D27/01
Filed: 2015-08-28
Abstract: An assembly jig for assembling a foundation structure comprised of a first layer of a plurality of parallel timber poles and a second layer of a plurality of parallel timber poles at an angle to and resting on said first layer of poles, the first and second layer poles at at least one intersection thereof being secured together by a dowel located in a hole in the second layer pole and in an axially aligned hole in the first layer pole, said assembly jig comprising: (i) a substructure to be temporarily secured to a first layer pole at said intersection, (ii) an attachment to be temporarily or permanently secured to said substructure and thereby be held securely relative the first layer pole, the attachment selected from at least one of a) a boring attachment that supports a borer for guided movement to create the hole to receive the dowel through the second layer pole and the axially aligned hole into the first layer pole at said intersection, and b) an assembly attachment that (i) functions to compress the first layer pole and second layer pole before the dowel is secured and/or (ii) provides at least one drill guide for a drill to create a hole to receive a pin to pass laterally into the dowel to thereby secure the dowel as part of the foundation structure.
Patent NZ-737786-A (NZ)
Title: Methods for treating autism spectrum disorder and associated symptoms
Inventor: ADAMS JAMES
IPC: A61K35/38
Filed: 2016-05-23
Abstract: The present disclosure relates to compositions and methods for treating autism spectrum disorder (ASD) by restoring an ASD patient’s gut microbiota. These methods can be used with ASD patient with or without ongoing gastrointestinal symptoms. Provided here is a method for ASD treatment in a subject in need thereof comprising or consisting essentially of administering a therapeutic composition comprising a fecal microbe or a fecal microbiota preparation to the subject. Also provided here is a method comprises administering an antibiotic to a human subject; subjecting the human subject to a bowel cleanse; and administering purified fecal microbiota to the human subject. Further provided are evaluation and quantitative characterization of patient symptom improvements upon treatment described here. In a particular embodiment, the fecal microbe preparation comprises a substantially complete fecal microbiota from a stool sample of a neurotypical donor for treating an impairment in social interaction related to ASD, wherein it is to be orally administered according to a first and second dosing schedule wherein the first dosing schedule comprises an induction dose and the second dosing schedule comprises a lower maintenance dose.
Patent NZ-739521-A (NZ)
Title: Pharmaceutical compositions
Inventor: VALCARCE LOPEZ MARIA CARMEN
IPC: A61P25/28
Filed: 2013-10-02
Abstract: The present invention relates to methods of treatment using [3-(4-{ 2-butyl-1-[4-(4-chloro-phenoxy)-phenyl]-1H-imidazol-4-yl} -phenoxy)-propyl]-diethyl amine (”COMPOUND I”) or a pharmaceutically acceptable salt thereof. In various embodiments, the methods of treatment include treatment of mild-to-moderate dementia of Alzheimer’s type, diabetes, insomnia, and other indications. The present invention also relates to pharmaceutical compositions comprising COMPOUND I or a pharmaceutically acceptable salt thereof.
Patent NZ-741421-A (NZ)
Title: Methods for freeze-drying and rehydrating biologics
Inventor: GENIN NOEL YVES HENRI JEAN
IPC: A61K9/19
Filed: 2015-05-13
Abstract: The present disclosure pertains to lyophilized compositions comprising elements of the culture medium of protozoa and at least one cryoprotectant as well as processes for obtaining lyophilized compositions containing freeze-dried protozoa of an intracellular nature and being devoid of protozoal host cells, the composition containing a moisture content of less than 12% by weight and being capable of reconstitution to restore said protozoa to viable and infectious states. Said lyophilised compositions comprise a culture medium selected from: DMEM, RPMI or PBS; a cryoprotectant selected DMSO, a monosaccharide, a disaccharide, an oligosaccharide, a polysaccharide or a mixture thereof; and further comprising one or more of: an osmoprotectant which is ectoine, an anti-oxidant selected from GSH, EGCG, ascorbic acid or a mixture thereof, and/or another additive which is proline.
Patent NZ-746202-A (NZ)
Title: Probiotic fortified food products and methods of manufacture
Inventor: SHANTANU DAS
IPC: A21D13/00
Filed: 2014-06-25
Abstract: The present invention relates to probiotic fortified food products and methods of manufacturing same. More specifically, the invention relates to a probiotic fortified food product wherein at least a portion of a surface of the food product includes an applied composition including at least one probiotic microorganism, wherein, other than the probiotic microorganism(s), the composition only includes components which are either fully milk-derived or are inherently found in milk; and wherein the composition has a probiotic microorganism cell count of above 7 log CFU ml-1.
Patent NZ-750131-A (NZ)
Title: Microorganism having acyltransferase activity and uses thereof
Inventor: LEE SUNG GUN
IPC: C12N15/70
Filed: 2017-07-19
Abstract: The present invention relates to a novel polypeptide of acyltransferase or a microorganism comprising the same; a composition for preparing N-acetyl-L-methionine comprising the polypeptide or microorganism; and a method for preparing N-acetyl-L-methionine using the polypeptide or microorganism. In addition, the present invention relates to a polynucleotide encoding the polypeptide and an expression vector comprising the polynucleotide. Since the microorganism comprising the novel acyltransferase of the present invention enhances the activity of the acyltransferase, the microorganism of the present invention can be efficiently used to produce N-acetyl-L-methionine by acetylating L-methionine.
Patent NZ-754448-A (NZ)
Title: Post driver improvements
Inventor: BENJAMIN CLIVE MCLEAN
IPC: E02D7/08
Filed: 2018-06-12
Abstract: Described is a block for the post driver configured to move along a driving axis, the block having a top end and a bottom end, and a pathway substantially parallel to the driving axis and between the top end and the bottom end; and a slider configured to move along the pathway, the top end including a barrier that prevents the slider moving in a substantially upwards direction above the top end. Also described is post driver including a post cap configured to cooperate with a top of a post; a block configured to move along a driving axis and to impact the post cap to drive the post in a substantially downwards direction; and a connector configured to releasably connect the post cap to the block, wherein when the connector is connecting the post cap to the block a gap between the post cap and the block decreasing causes the link to release, disconnecting the post cap from the block.
Patent PT-102721-A (PT)
Inventor: GONCALVES ANTONIO M D A ROCHA
IPC: A61P35/00
Filed: 2002-02-01
Abstract: The invention refers to macrocyclic tetrapirrolic compounds of the family of porphyrins (structure I), chlorins (structure II) and bacteriochlorins (structure III) characterized by the presence of hydrogen or halogen atoms and/or phenyl groups with halogens in the ortho position (with or without hydroxyl groups in the meta position) in positions 5,10,15 and 20 of the macrocycle, and hydrogen or halogen atoms or akyl, vinyl, carboxy, carboxyalkyl, alkoxycarbonyl, alkoxycetoalkyl, alcoxycetoaryl, acetoxy or hydroxyalkyl groups in positions 2,3,7,8,12,13,17 and/or 18.
Patent PT-106424-A (PT)
Title: Sistema e método para estimulação proprioceptiva, monitorização e caracterização de movimento
Inventor: CUNHA JOAO PAULO TRIGUEIROS DA SILVA
IPC: A61H23/00
Filed: 2012-07-02
Abstract: SISTEMA E MÉTODO PARA ESTIMULAÇÃO PROPRIOCEPTIVA, MONITORIZAÇÃO E CARACTERIZAÇÃO DE MOVIMENTO QUE COMPREENDE: UM COMPONENTE PARA INTERVENÇÃO PROPRIOCEPTIVA E OUTRO PARA CARACTERIZAÇÃO DE MOVIMENTO. OS DOIS COMPONENTES ESTÃO ACOPLADOS DE FORMA A PODEREM SER UTILIZADOS (VESTIDOS) EM AMBULATÓRIO SOBRE OS MEMBROS SUPERIOR E INFERIOR DO LADO DO CORPO QUE APRESENTA O DÉFICE MOTOR. ESTE DISPOSITIVO PODE SER APLICADO NA ÁREA DA SAÚDE, NOMEADAMENTE EM NEURORREABILITAÇÃO, EM ÁREAS DE ACTIVIDADE CIENTÍFICA BÁSICA OU CLÍNICA, EM PRODUTOS DIRIGIDOS A SEGMENTOS DE MERCADO LÚDICOS (E.G. DANÇA, VIDEOJOGOS, TV INTERACTIVA, CINEMA 3D) E NA ÁREA DE DESPORTO E MELHORIA DE PERFORMANCE MOTORA EM COMPETIÇÃO. O SISTEMA COMPREENDE UM MÓDULO PRINCIPAL PARA CONTROLO, ESTIMULAÇÃO PROPRIOCEPTIVA E QUANTIFICAÇÃO DE MOVIMENTO (1), MÓDULOS DE CONTROLO, ESTIMULAÇÃO PROPRIOCEPTIVA E QUANTIFICAÇÃO DE MOVIMENTO (2, 3) E ELEMENTOS DE ESTIMULAÇÃO PROPRIOCEPTIVA (16).
Patent PT-108225-A (PT)
Title: Matéria plástica multicamadas com revestimento exterior de cortiça
Inventor: JOÃO TOMÁS FRAÚSTO DE MASCARENHAS GAIVÃO
IPC: B65D53/00
Filed: 2015-02-13
Abstract: O PRESENTE PEDIDO DE PATENTE É RELATIVO A MATÉRIA PLÁSTICA MULTICAMADAS COM REVESTIMENTO EXTERIOR DE CORTIÇA (1). O PRESENTE PEDIDO DE PATENTE COMPREENDE AINDA A UTILIZAÇÃO DA MATÉRIA PLÁSTICA MULTICAMADAS COM REVESTIMENTO EXTERIOR DE CORTIÇA (1) NA FORMA DE PELÍCULA FLEXÍVEL REMOVÍVEL PARA O FECHO E SELAGEM DE RECIPIENTES CONTENDO PRODUTOS ALIMENTARES, NOMEADAMENTE VINHO.
Patent PT-108763-A (PT)
Title: Método de poupança de energia para redes sem fios de localização tridimensional em tempo-real e sistema que o implementa
Inventor: OLIVEIRA JOSÉ EDUARDO GOMES
Filed: 2014-04-10
Abstract: PRESENTE INVENÇÃO ENQUADRA-SE NA ÁREA DOS SISTEMAS DE LOCALIZAÇÃO EM TEMPO-REAL DE PESSOAS E/OU BENS MÓVEIS, COM RECURSO A COMUNICAÇÕES SEM FIOS.É OBJECTO DA PRESENTE INVENÇÃO UM MÉTODO QUE PERMITE DIMINUIR SUBSTANCIALMENTE O CONSUMO DE DISPOSITIVOS MÓVEIS DE LOCALIZAÇÃO EM REDES SEM FIOS, POR VIA DA RECONFIGURAÇÃO AUTOMÁTICA DA POTÊNCIA DE TRANSMISSÃO DE CADA DISPOSITIVO MÓVEL (11) AO LONGO DE UM PROCESSO DE LOCALIZAÇÃO.NO MÉTODO DE POUPANÇA DE ENERGIA PARA REDES SEM FIOS DE LOCALIZAÇÃO TRIDIMENSIONAL EM TEMPO-REAL DA PRESENTE INVENÇÃO A POTÊNCIA DE TRANSMISSÃO DE PELO MENOS UM DISPOSITIVO MÓVEL (11) É CONFIGURADA, SENDO QUE O VALOR DE POTÊNCIA DE TRANSMISSÃO CONFIGURADO NO, PELO MENOS UM, DISPOSITIVO MÓVEL (11) VARIA INVERSAMENTE COM O NÚMERO DE LEITORES (12) QUE INTEGRAM UMA ZONA VIRTUAL (119) DEFINIDA.É TAMBÉM OBJECTO DA PRESENTE INVENÇÃO UM SISTEMA QUE IMPLEMENTA O MÉTODO.
Patent RU-94001223-A (RU)
Inventor: SURKOVA V K
IPC: A61K35/34
Filed: 1994-01-13
Abstract: FIELD: medicine, ophthalmology. SUBSTANCE: eye drops have water-soluble mixture of glycoseaminoglycans isolated from cattle eye cornea and sclera and, additionally, nipagin, sodium carboxymethylcellulose at the following ratio of components, wt.-%: mixture of glycoseaminoglycans, 0.1-1; nipagin, 0.1; sodium carboxymethylcellulose, 1; and physiological solution, the balance. Eye drops can be used for treatment of traumatic damages, trophic disorders and chemical burns. EFFECT: enhanced effectiveness.
Patent RU-94002712-A (RU)
Title: Method for increasing human organism resistance by applying phytoaeroions
Inventor: DUBINSKIJ R A
IPC: A61K36/84
Filed: 1994-02-04
Abstract: FIELD: medicine. SUBSTANCE: method involves administering phytoaeroions by inhaling finely dispersed electrically charged aerosol having water emulsion of essential oils or water decoctions of various analkaloid plants having no adaptogenic activity, electric charge carriers. The essential oils are introduced into the emulsion in 1:1000 proportion. The water decoctions are prepared in 1:50 proportion of water to raw materials. The emulsion or decoction are mechanically processed to prepare fine aerosol and additionally receive electric charge in leaving phytoaeroionizer device. Biologically active substance concentration in the room air, where the treatment takes place, is to be 1-2 mg/m. A treatment course has 25-30 treatments to be taken daily. When needed, the treatment course is repeated 2-3 months later as prophylaxis. EFFECT: enhanced effectiveness of treatment; reduced disease incidence.
Patent RU-94009944-A (RU)
Inventor: BERKOVSKIJ B S
IPC: B64C39/00
Filed: 1994-03-22
Abstract: FIELD: aeronautical engineering; ground-effect take-off and landing aeroplanes. SUBSTANCE: ground-effect machine has crew cabin 1 located inside wing 2, flap 3, elevens 4; fitted at wing tips are end plates 5; fairing panel or soft envelope - form-shaping member are mounted on upper surface of wing. Engines 8 are arranged inside wing. Weights 11 are located over entire wing span. Delta-shaped wing has straight trailing edge and flat upper and lower surfaces; to this end, wing profile has constant relative thickness over entire chord, but for rounded-off nose and wedge-shaped trailing-edge piece. EFFECT: enhanced transportation efficiency and development of high speeds; enhanced trimming and stability at take-off, landing and cruising; vehicle may be used for transportation of large cargoes without disassembly to hard-to-reach regions of country and planet. 2 cl, 7 dwg
Patent RU-94012997-A (RU)
Inventor: KULAGIN V F
IPC: A61K41/17
Filed: 1994-04-12
Abstract: FIELD: medicinal industry, virology. SUBSTANCE: sealed ampoules containing dry interferon preparation were put in casettes and subjected for twice gamma-irradiation at total dose 15-25 kGr. This treatment provides the complete inactivation of viral contaminants and safety with regard to lymphotropic viruses. Antiviral activity of interferon is retained. Preparation shows virological and bacteriological sterility, nontoxicity and harmless. EFFECT: improved method of inactivation.
Patent RU-94020920-A (RU)
Inventor: LINKEVICHJUS S P
IPC: G01S13/00
Filed: 1994-06-03
Abstract: FIELD: radar engineering; radar systems using linear frequency-modulated signals. SUBSTANCE: echo signals of target accepted by receiving antenna, passed through high-frequency amplifier, and converted in mixer are additionally stretched prior to being processed in optimal string due to their addition in adders to their copies obtained at input of each optimal filter of strip by delaying received echo signals in group of (M-1) delay lines for time equal to sounding signal length; to eliminate phase difference between echo signals and their copies, initial oscillation phases of echo-signal copies are eliminated by means of groups of (M-1) phase shifters at input of each optimal filter. EFFECT: improved range measurement accuracy without increasing signal frequency deviation.
Patent RU-94027013-A (RU)
Inventor: MINASJAN M A
IPC: F16F7/14
Filed: 1994-07-18
Abstract: FIELD: mechanical engineering. SUBSTANCE: vibration insulation support has flexible member 1 made up as arc-like pieces of a steel rope that form a rotation body like a hyperboloid, three plates 2,3,4 made up as rings two of which, 2 and 3, are in the end oppositely-lateral planes of the hyperboloid with fixed ends of the rope pieces of the flexible member and are secured to foundation. The third ring 4 is mounted in the central lateral plane of symmetry and can move longitudinally or be fixed to an engine. EFFECT: enhanced vibration insulation. 3 cl, 9 dwg
Patent RU-94029841-A (RU)
Inventor: KIRILJUK A KH
IPC: E02F3/80
Filed: 1994-08-17
Abstract: FIELD: earth-moving machinery, single-bucket loaders. SUBSTANCE: support frame of loader working equipment has longitudinal beams with rear end fasteners and units to fasten front ends of longitudinal beams to base vehicle, and cross beam secured to front portions of longitudinal beams. Length of cross beam exceeds distance between outer sides of longitudinal beams. Ends of cross beam projecting beyond longitudinal beams are provided with holes. Front ends of longitudinal beams have additional members to fasten beams to base vehicle. Rear ends of longitudinal beams are arranged apart and are furnished with coaxial holes on end sections. Longitudinal beams are braced by rigid members at place of bending. Rigid members can have eyes for additional fastening of frame to base vehicle. Front ends of longitudinal beams have additional eyes for connecting bulldozer equipment. EFFECT: enhanced reliability of fastening the working equipment. 2 dwg