baber/WOPTO huggingface dataset:
Patent AU-2019210656-C1 (AU)
Title: MHC class I epitope delivering polypeptides
Inventor: POMA ERIC
IPC: C12N15/62
Filed: 2019-08-02
Granted: 2023-06-22
Abstract: The present invention is directed to T-cell epitope delivering polypeptides which deliver one or 
more CD 8+ T-cell epitopes to the MHC class I presentation pathway of a cell, including 
toxin- derived polypeptides which comprise embedded T-cell epitopes and are de-immunized.  
5 The present invention provides cell-targeted, CDS+ T-cell epitope delivering molecules for the 
targeted delivery of cytotoxicity to certain cells, e.g., infected or malignant cells, for the 
targeted killing of specific cell types, and the treatment of a variety of diseases, disorders, and 
conditions, including cancers, immune disorders, and microbial infections. The present 
invention also provides methods of generating polypeptides capabl e of delivering one or more 
10 heterologous T- cell epitopes to the MHC class I presentation pathway, including polypeptides 
which are I ) B- cell and/or CD4+ T-cell de-immunized, 2) comprise embedded T-cell 
epitopes, and/or 3) comprises toxin effectors which retain toxin functions.
Patent RU-2168628-C1 (RU)
Title: Способ разработки пластовых месторождений
Inventor: SHESTAKOV V A
IPC: E21C41/18
Filed: 2000-03-20
Granted: 2001-06-10
Abstract: Изобретение относится к горной промышленности, в частности к системе разработки длинными столбами, и предназначено для повышения качества добываемого угля и улучшения условий поддержания подготовительных выработок. Способ разработки пластовых месторождений состоит в том, что вначале на месте будущего штрека проходится по углю камера шириной, равной ширине будущего штрека. Параллельно с ней через целик угля шириной 2-4 м проходится еще одна камера для складирования породы шириной достаточной для размещения в ней породы от последующей проходки и ремонта штрека. При складировании породы в камере через определенное расстояние выкрепляются выработки от массива угля до штрека (сбойки), чтобы обеспечить в будущем проветривание лавы нижнего этажа. Использование предлагаемого способа разработки пластовых месторождений позволяет повысить устойчивость подготовительных выработок за счет применения комбинированной охраны "целик-бутовая полоса", исключить утечки воздуха, снизить не только зольность добываемого угля за счет оставления породы в шахте, но и более полно извлечь его запасы. 1 ил.
Patent RU-2185659-C1 (RU)
Title: Device for separating object image edges
Inventor: DEGTJAREV S V
IPC: G06K9/46
Filed: 2000-12-28
Granted: 2002-07-20
Abstract: FIELD: computer engineering; computer vision systems. SUBSTANCE: device that may be used in systems for input and processing of data transmitted to computer has image sensor, buffer memory, AND gate, generator, neuron-matrix processor unit, analog-to-digital converter, horizontal and vertical pulse separating unit, and PCI bus controller. EFFECT: enhanced precision and speed of image edges separation. 5 dwg
Patent RU-2190759-C1 (RU)
Title: Hydraulic perforator
IPC: E21B43/114
Filed: 2001-04-23
Granted: 2002-10-10
Abstract: FIELD: oil, gas and water extraction, perforation of wells. SUBSTANCE: perforator has body with cylinders and conduit, piston with hole coming in the form of conical or cylindrical sections with common axis. Piston is located in one cylinder with degree of freedom to move along and around own axis and limited axial movement. It is supported by butt and cylindrical bearings. Rotation axis crosses axis of hole in parallel planes at angle chosen on basis of assignment of number of revolutions of piston and maintenance of perforation potential of outgoing jet. Distance between points of crossing of these axes with internal surface of perforated column is equal to planned radius of perforation conduit. To limit axial movement of piston which maximum value is computed on condition of its non-power contact with internal surface of column during its maximum stroke internal butt of piston carries flange along which holes inside conical section of hole are drilled. External butt surface of piston comes in the form of part of sphere with conduits and recess in its butt around through cylindrical hole in piston and radius equal to radius of internal surface of column. Conical transitions to conduit supplying liquid are made inside body in front of piston. EFFECT: reduced perforation time. 1 cl, 4 dwg
Patent RU-2195197-C1 (RU)
Inventor: ASEEV A V
IPC: A61B17/00
Filed: 2001-06-29
Granted: 2002-12-27
Abstract: FIELD: medicine, operative surgery. SUBSTANCE: in area of an jugular fossa one should bluntly form a foramen into anterior mediastinum with the help of a Fyodorov's clamp. Sternotomy is started from an angle parallel to the body by cutting a circumferential lamella and spongiose layer under a finger control along the whole sternal length up to posterior cortical lamella. The latter is crossed with a guillotine sternotome in area of a handle. At the level of the first intercostal space one should insert the branches of stomatological mouth dilator to separate the edges for 5-10 mm. In retrosternal cellular tissue of sternotomy area a canal is formed with fingers. The cutting of posterior cortical lamella is carried out under a sharp angle to a sternum under a finger control from the side of anterior mediastinum by replacing a mouth dilator into other intercostal spaces, if necessary. EFFECT: decreased duration terms and traumaticity of operation. 1 ex
Patent RU-2197820-C1 (RU)
Title: Method of protection of vegetating solanaceae crops from destructive insects
Inventor: IVAKHNENKO O A
IPC: A01N63/12
Filed: 2001-07-12
Granted: 2003-02-10
Abstract: FIELD: agriculture. SUBSTANCE: method involves spraying plants with suspension of endomopathogenic nematodes with addition of "Biostat". Nematode of strain Heterorhabditis bacteriophora is used as endomopathogenic nematodes. EFFECT: enhanced effectiveness of control of pests.
Patent RU-2192366-C1 (RU)
Title: Aircraft control system
Inventor: SIMONOV M P
IPC: B64C15/02
Filed: 2001-07-13
Granted: 2002-11-10
Abstract: FIELD: aircraft control systems. SUBSTANCE: proposed system includes aircraft position selectors showing change of aircraft position relative to axes of body-axis coordinate system, sensors of angular rate relative to coordinate system, angle- of-attack and side-slip sensors, flight altitude sensors, ram air pressure sensors and g-load sensor, undercarriage leg position and compression sensors, drives of aerodynamic aircraft position control members relative to axes of coordinate system, devices changing direction of engine thrust vector and drive control unit which is connected to selectors and sensors including computers of pitch, heading and roll control channels, adders of signals of computers of pitch, roll and heading control channels, control signal correctors of units changing direction of thrust vector which may be provided with devices for forming computers, correctors and adders or may be made for performing functions corresponding to combinations of computers, correctors and adders. EFFECT: possibility of controlling aircraft at super-low flying speeds, performing maneuvers at high angles of attack at increased rate of change of position. 5 cl, 1 dwg
Patent RU-2194853-C1 (RU)
Title: Устройство для исследования скважин
Inventor: CHESNOKOV V A
IPC: E21B47/06
Filed: 2001-07-26
Granted: 2002-12-20
Abstract: Изобретение относится к эксплуатации нефтяных скважин, а именно к исследованиям эксплуатирующихся скважин. Техническим результатом является повышение эффективности и надежности устройства. Для этого устройство содержит струйный насос с активным соплом, камерой смешения, диффузором и каналом подвода откачиваемой из пласта жидкости и запорный элемент с седлом, установленным параллельно струйному насосу. Причем через осевой канал запорного элемента пропущен каротажный кабель с подсоединенным к нему геофизическим прибором. Активное сопло с камерой смешения направлено вверх, а в зазоре между корпусом струйного насоса и стенкой обсадной колонны против камеры смешения установлена самоуплотняющаяся манжета. 1 ил.
Patent RU-2195717-C1 (RU)
Title: Energy generating device
Inventor: KIRKINSKIJ V A
IPC: G21B3/00
Filed: 2001-08-23
Granted: 2002-12-27
Abstract: FIELD: nuclear physics; theoretical estimates of rate of nuclear reaction in palladium deuteride. SUBSTANCE: device used for energy generation due to deuterium sorption-desorption in fine-grain palladium depends for its operation on nuclear reaction between deuterium atoms, its rate rising in crystalline structures of working materials suffering reversible isostructural phase transforms involving changes in their deuterium content. Device has working medium reactor, gas pressure measuring and control system, heating and temperature control system, and released heat transfer and application system. Reactor is made in the form of coaxially disposed tubes equipped with locks which pressurize space accommodating working medium in the form of powder or film on substrate. Heaters are mounted in end parts of tubes for building up temperature gradient variable in direction along reactor axis. Heat-transfer apparatus of primary circuit abuts against reactor directly or through heat-transfer bushing on side radially opposite to position of heaters. Device is available of various modifications ensuring simultaneous sorption of deuterium in working material within heated part of reactor and desorption in its cooled part. EFFECT: enhanced effectiveness of using released energy; enhanced reliability and ability of automating the process. 26 cl, 9 dwg, 1 tbl
Patent RU-2191239-C1 (RU)
Inventor: VOLKODAEV JU K
IPC: E04C2/26
Filed: 2001-10-23
Granted: 2002-10-20
Abstract: FIELD: construction engineering and building materials; applicable in construction, in enclosing structures of residential, public and industrial buildings. SUBSTANCE: three-layer wall panel consists of external and internal reinforced concrete layers between which intermediate warmth-keeping layer is located. Concrete layers are interconnected by flexible ties. Three-layer wall panel has a window opening. Upper horizontal end of external concrete layer forms rain ridge with α angle of inclination of its working surface equaling 40-50 deg, and lower horizontal end of external concrete layer has a projection in the form of tooth with β angle of inclination of its working surface equaling 55-65 deg. Warmth-keeping intermediate layer is made in the form of composite core from polyurethane foam plates edged with semirigid mineral wool members over outer and inner perimeters. Width S of each mineral wool member equals to 0.5-2.2 of thickness L1 of composite core. Upper end of internal concrete layer is deflected downward relative to upper ends of opposite ridge of external concrete layer and composite core through value T1 equaling 0.9-4.0 of thickness L2 of internal concrete layer. Lower end of internal concrete layer is also deflected downward relative to lower end of tooth of concrete external layer through value T2 equaling 0.35-0.45 of thickness L2 of internal concrete layer. EFFECT: higher quality and accuracy of manufactured articles of prefabricated concrete and reinforced concrete, elimination of cold bridges in joints between adjacent enclosing panels, increased rigidity of building structures, higher seismic stability and prolonged serviced life of buildings. 3 cl, 8 dwg
Patent RU-2206450-C1 (RU)
Title: Method for adobe brick piling for thermal treatment
Inventor: GALEEV I A
IPC: B28B15/00
Filed: 2001-11-22
Granted: 2003-06-20
Abstract: FIELD: production of brick. SUBSTANCE: the method consists in transference of bricks to an accumulating conveyer, stepwise setting on it of a layer of bricks, subsequent piling. Before the beginning of work of the piler it is displaced to a position providing for a grip of the first layer, and before the next lifting and transference of bricks to the buggy the position of the initial row is determined with the aid of a computer-controlled unit. The rated coordinate in the zone of action of the piler of the final row of the next layer is determined in accordance with the piling chart, the actual position of the initial row of the next layer after displacement of the accumulating conveyer is determined with the aid of a registering device. The coordinate of the final row of the next layer is corrected with due account made for the actual position of the initial row, and the piler is automatically displaced to a position providing for a grip of the next layer of bricks. EFFECT: enhanced speed of piling. 2 cl
Patent RU-2207065-C1 (RU)
Inventor: ASEEV A V
IPC: A61B17/56
Filed: 2002-05-27
Granted: 2003-06-27
Abstract: Изобретение относится к торакальной хирургии. Разрез кожи проводят параллельно медиальному краю лопатки, отступя на 2-3 см, и продлевают его на 5-6 см ниже нижнего угла лопатки. После полного освобождения ребра от надкостницы его пересекают на расстоянии 5 см от головки. Производят этапное поднадкостничное удаление верхних четырех ребер с задними отделами 5-9 ребер на протяжении 5 см. Фрагментацию переднебоковых отделов 5-9 ребер производят вторым этапом через 2-3 недели из отдельных разрезов по краю большой грудной и широчайшей мышцы спины с поднадкостничным удалением каждого ребра в каждом разрезе до 5 см. Способ позволяет снизить травматичность и кровопотерю.
Patent RU-2222085-C1 (RU)
Title: Phase mismatch speed relay
Inventor: PUKHOV I K
IPC: H02J3/40
Filed: 2002-06-07
Granted: 2004-01-20
Abstract: FIELD: supply mains voltage control. SUBSTANCE: phase mismatch relay designed for operation in response to inadmissible speed of phase mismatch between generator and supply mains has three comparators, two AND gates, clock generator, algebraic adder, short-pulse shaper, shift register, averaging filter, and final element. EFFECT: enlarged functional capabilities of relay. 2 cl, 3 dwg
Patent RU-2227512-C1 (RU)
Title: Method for preparing combined fodder premix
Inventor: KVASENKOV O I
IPC: A23K1/00
Filed: 2002-10-23
Granted: 2004-04-27
Abstract: FIELD: fodder industry. SUBSTANCE: method involves milling a filling agent comprising grains or products of its processing and addition of special supplements to a filling agent using the preparation from biomass of micromycetes of genus Mortierella nigrescens as a component of special supplements. The preparation is prepared by sequential extraction of biomass of micromycetes Mortierella nigrescens with nonpolar extractant in supercritical state, water, alkali, water, acid, water, alkali and water and the following combination of the first extract with solid residue. Invention provides enhancing stability in storage. EFFECT: improved preparing method. 2 ex
Patent RU-2231574-C1 (RU)
Inventor: AFANAS EV S V
IPC: C23F11/14
Filed: 2003-04-23
Granted: 2004-06-27
Abstract: FIELD: corrosion protection. 
     SUBSTANCE: aqueous carbon steel corrosion inhibitor, which may be used in production and transportation of formaldehyde products such as urea-formaldehyde concentrate, is added in amounts from 0.1 to 3% on the weight of urea-formaldehyde concentrate and 10-40% polyamine, 0.01-4% formaldehyde, and 0.01-3.5% ammonia, said polyamine having general formula    
     wherein n = 0 or 1, m = 0 or 1, and n+m = 0-2. 
     EFFECT: expanded corrosion protection possibilities. 
     1 tbl
Patent RU-2226608-C1 (RU)
IPC: E21F15/00
Filed: 2003-06-23
Granted: 2004-04-10
Abstract: Изобретение относится к горной промышленности и может быть использовано при проходке и погашении горных выработок. Оно направлено на обеспечение возможности передвижения щита как вперед, так и назад для погашения выработки после ее проходки без просадки земной поверхности. Способ включает разработку породы, ее транспортирование, возведение крепи и передвижение щита к забою. Для погашения выработки щит передвигают в обратном направлении к устью выработки с одновременной подачей забутовочного материала. В щите со стороны забоя устанавливают опорный элемент, удаляют часть крепи, образовавшееся пространство перед опорным элементом заполняют забутовочным материалом. Затем одновременно передают усилие на щит для его передвижения к устью выработки и на опорный элемент для его перемещения вдоль выработки в сторону забоя и подпрессовки забутовочного материала. Устройство представляет проходческий щит с корпусом из трех частей. Передняя часть выполнена в виде ножевой оболочки, в средней по ее периметру размещены гидродомкраты перемещения щита, а хвостовая часть корпуса выполнена в виде оболочки для возведения крепи. Щит имеет опорный элемент, установленный с возможностью перемещения относительно продольной оси корпуса и выполненный с возможностью перекрытия всего сечения ножевой оболочки корпуса. Гидродомкраты перемещения опорного элемента установлены в средней части корпуса с возможностью одновременного отталкивания его от щита. Ножевая оболочка выполнена из внутреннего конического и наружного цилиндрического ножевых колец. Гидродомкраты перемещения щита установлены с возможностью соединения с неподвижно закрепленными на устье горной выработки стержнями с возможностью подтягивания его в сторону крепи. 2 с.п. ф-лы, 2 ил.
Patent RU-2238808-C1 (RU)
Inventor: IVANOV A A
IPC: B21B1/02
Filed: 2003-06-26
Granted: 2004-10-27
Abstract: FIELD: manufacture of rolled products, in particular, methods for rolling of blanks with increased stretch extent. 
     SUBSTANCE: method involves rolling blanks by means of pair of rolls rotating in opposite directions; providing deflection of vectors of circumferential speed of rolls from rolling axis in plane of said axis combined with turning of blank around rolling axis; providing alternate rolling process with intervals between reduction processes at relative reciprocation movement of rolls and blank rotation axes along axis of rolling resulting in formation of deformation cone on blank. Rolling process is performed with the use of rolls of variable radius, said rolls defining round pass, with angle of deflection of circumferential speed vector of each roll from rolling axis being regulated by mathematical dependence taking into account such parameters, as angle of turning of blank around longitudinal axis, roll shaft spacing, rolling radius of rolls, and length of deformation cone. 
     EFFECT: increased efficiency of step-by-step rolling process and elimination of employment of special tilting devices synchronized with rolling stand drive. 
     3 dwg
Patent RU-2255659-C1 (RU)
Inventor: LAZEBNIK L B
IPC: A61B8/00
Filed: 2003-12-04
Granted: 2005-07-10
Abstract: FIELD: medicine. 
     SUBSTANCE: method involves carrying out ultrasonic examination. Hepatic cholestasis being observed, morphologic examination of hepatic bioptate is carried out. Intralobular lymphoid cellular infiltrate on the hepatic cells necrosis place and nonuniform thickness of central vein wall, moderately marked pericentral and focal perihepatocellular fibrosis being available in combination with lipofuscin deposit and epitheliocyte desquamation in biliary ducts, TTV-caused chronic hepatitis is considered to be diagnosed. 
     EFFECT: high accuracy of diagnosis.
Patent RU-2250374-C1 (RU)
Title: Driving shield rotor
Inventor: STOGOV S N
IPC: E21D9/08
Filed: 2003-12-17
Granted: 2005-04-20
Abstract: FIELD: mining industry. 
     SUBSTANCE: rotor is made in form of cylindrical body, on working surface of which cutter holders are radially placed, each of which is made in form of shaft, freely placed in cylindrical groove of rotor body. Along whole length of each cutter holder cutting elements are mounted with hard-alloy inserts. Between cutter holders cutting elements are placed, made in form of rectangular prisms with hard-alloy inserts. 
     EFFECT: higher efficiency. 
     3 dwg
Patent RU-2250074-C1 (RU)
Title: Oxiorespirator
Inventor: PIL SHCHIKOVA A S
IPC: A61B5/08
Filed: 2003-12-29
Granted: 2005-04-20
Abstract: FIELD: medical engineering. 
     SUBSTANCE: device has inlet tube having temperature gage which output is connected to input of unit for calculating breathing period and indication unit. It has infrared transducer placed on inlet tube bite-board. Unit for calculating blood saturation with oxygen is connected to infrared transducer output. The integrator and indicator are connected in series to the unit to additionally enable blood saturation with oxygen and controlling dependency on breathing period. Keyboard which output is connected to the second input of the integrator is available. The third input is connected to output of unit for calculating breathing period. 
     EFFECT: wide range of functional applications. 
     1 dwg
Patent RU-2254001-C1 (RU)
Inventor: OSTRIKOV A N
IPC: A23B7/02
Filed: 2003-12-31
Granted: 2005-06-20
Abstract: FIELD: food-processing industry, in particular, production of food concentrates. 
     SUBSTANCE: method involves washing, inspecting, gauging, cleaning, cutting, blanching and drying; providing drying in two sequential repeatedly alternating short-time stages: first stage including processing potato cubes in dense 55-mm high layer with overheated steam of atmospheric pressure, and second stage including processing in fluidized bed at predetermined velocity and temperature of overheated steam. 
     EFFECT: increased heat efficiency and intensity of drying process and improved quality of ready product. 
     2 dwg, 6 tbl
Patent RU-2257285-C1 (RU)
Inventor: STOLJAROV I I
IPC: B23K26/34
Filed: 2004-01-14
Granted: 2005-07-27
Abstract: FIELD: working metal by laser beam. 
     SUBSTANCE: method comprises supplying fusing material by means of a jet of transporting gas to the nozzle of laser installation coaxially to the laser beam. The laser installation is adjusted to focus the laser beam inside the nozzle at a distance of 3-7 mm from the nozzle exit. The focus of the flow of the powder fusing material is outside of the nozzle at a distance of 6-10 mm. The particles of the zirconium dioxide are embedded into the melt of the heat-resistant high alloy and are distributed homogeneously through the bulk of the plated metal. 
     EFFECT: enhanced resistance to heat. 
     1 ex
Patent RU-2255117-C1 (RU)
Inventor: LEONT EV L I
IPC: C21B13/02
Filed: 2004-04-12
Granted: 2005-06-27
Abstract: FIELD: ferrous metallurgy; production of sponge iron in shaft furnaces with the use of converted natural gas. 
     SUBSTANCE: proposed method includes reduction of descending iron ore materials in counter-flow with reducing gas at temperature of 800-1050°C at simultaneous recirculation and heating of process blast-furnace gas and catalytic reforming of natural gas in external return cycle with addition of oxidizing agent. Introduced into reformer as oxidizing agent is vapor-and-oxygen mixture at flow rate of up to 30 m 3 /t. Prior to mixing the vapor with oxygen, it is superheated to temperature not below 110°C; content of oxygen introduced into mixture does not exceed 40%. Blast-furnace gas is dehumidified before compression for obtaining required moisture content. 
     EFFECT: increased output of shaft furnace; reduced power requirements. 
     5 cl, 2 dwg, 2 tbl