baber/WOPTO huggingface dataset:
Patent UY-23484-A1 (UY)
Title: Procedimiento para la preparacion de heteroarilaminas como nuevos inhibidores de la acetilcolinterasa.
Inventor: YUHPYNG L CHEN
IPC: A61P25/28
Filed: 1992-10-02
Abstract: Esta invención se refiere a métodos de preparación de heteroarilaminas de fórmula (I) (figura 1) y a sales farmacéuticamente aceptables de las mismas, donde: R1 es fenil, fenil-alquilo o un radical heteroarilmetilo; R2 y R3 entre otras posibilidades, unidos a átomos de carbono adyacentes, forman junto a los átomos de carbono a los que están enlazados, un anillo de 5 o 6 miembros donde cada átomo del anillo es carbono, nitrógeno u oxígeno, por ejemplo un anillo de metilendioxi, etilendioxi o lacatama; X es nitrógeno; Y es azufre; Z es oxígeno o azufre. El procedimiento consiste en hacer reaccionar un compuesto de fórmula (XV) (figura 2), con un compuesto R1L, donde L es un grupo desplazable en presencia de una base. Ejemplo no limitante: 1-(2-metil-1H-bencimidazol-5-il)-3-[1-(fenilmetil)-4-piperidinil]-1-propanona. Los compuestos de fórmula (I) son inhibidores de la acetilcolinterasa y se utilizan para aumentar la memoria en los pacientes de demencia y enfermedad de Alzheimer.
Patent UY-26372-A1 (UY)
Title: "imidazo-3-il-aminas bicíclicas procedimiento para su preparación y medicamentos que las contienen "
Inventor: GERLACH DR MATTHIAS
IPC: A61K31/53
Filed: 2000-10-05
Abstract: Imidazo-3-il-aminas bicíclicas de la fórmula generamente aceptables, procedimiento para su preparación y medicamentos que contienen como sustancia activa al menos un imidazo-3- il-amina bicíclica de la fórmula general I en forma de su base o una sal farmacéuticamente aceptable.
Patent UY-26375-A1 (UY)
Title: Virosomas dosper cationicos
Inventor: WRLTI ERNST RUDOLF
Filed: 2000-10-06
Abstract: La presente invención está relacionada con un virosoma catiónico que incluye al menos un péptido activo indeuctor de la fusión que es una hemaglutinina de un virus distinto del Sendai y donde la membrana del virosoma incluye entre 5% y 30% en peso, con respecto a los lípidos totales, de 1, 3-dioleoiloxi-2-(6-carboxi-espermil)-pripilamida (DOSPER) en combinación con otros lípidos incluyendo la fosfatidilcolina (FC) o un derivado suyo y opcionalmente fosfatidiletanolamina (FE) y/u otros lípidos catiónicos. Los virosomas son altamente eficaces en el transporte de material cargado negativamente, especialmente compuestos de ácido nucleicos, a las células diana. Esta invención también está relacionada con un procedimiento para la fabricación de los virosomas y los usos de estos para propósitos de diagnósticos, m cosméticos, médicos o científicos.
Patent UY-27474-A1 (UY)
Title: Formulación de dosificación oral de fusion instantanea.
Inventor: KOTHARI SANJEEV S
IPC: A61K9/00
Filed: 2002-10-07
Abstract: Una forma de dosificación farmacéutica de fusión instantánea que comprende un medicamento, un superdesintegrante, un agente de dispersión y un aglutinador, en donde el medicamento es aripiprazol, entecavir, cefprozil, pravastatina, captopril, gatifloxacina, desquinolona, omapatrilat o irbesartan y en donde el agente de dispersión es silicato de calcio y en donde el superdesintegrante está comprendido de dos o más agentes seleccionados del grupo que consiste de crospovidona, croscarmelosa sodio, glicolato de sodio y almidón, hidroxipropil celulosa substituida a un nivel bajo o almidón pregelatinizado.
Patent UY-27639-A1 (UY)
Title: Composiciones farmacéuticas de inhibidores de la proteína de transferencia de ésteres de colesterilo
Inventor: WILLIAM CURATOLO
IPC: A61K47/38
Filed: 2003-01-31
Abstract: Una composición farmacéutica comprende una dispersión amorfa sólida de un inhibidor de la proteína de transferencia de ésteres de colesterilo y un polímero que aumenta la concentración.
Patent UY-28329-A1 (UY)
Title: Dispositivos de tratamiento oral que incluyen una barrera en forma de capa delgada y flexible y una composición de tratamiento o una composicion de adhesion tipo endoesqueleto.
Inventor: MCLEAN BRUCE S
IPC: A61C19/06
Filed: 2004-05-21
Abstract: Dispositivos de tratamiento oral que incluyen una barrera en forma de capa y una composición de tratamiento oral, y opcionalmente una composiciónb de adhesión auxiliar, que actúa como un endoesqueleto y contribuye asi, al menos parcialmente, en el mantenimiento de laforma de platillo dental de la barrera en capa, o de configuración de tipo platillo de la misma, antes de su uso. La barrera de capa protege a la composición de tratamiento oral y/o de adhesión del contacto con la saliva o la humendad durante su uso. Las composiciones de tratamiento y/o de adhesión auxiliares pueden ser desde pegajosas, hasta geles viscosos o incluso sólidas. Las mismas incluyen, preferiblemente, agentes de adhesión a los tejidos como poklímeros hidrofílicos.
Patent ES-160198-A1 (ES)
Title: DISPOSICIoN DE RUEDA GEMELA PARA RUEDAS DE PROA O PATINES DE COLA DE AVIONES
Filed: 1943-02-02
Abstract: Disposición de rueda gemela para ruedas de proa o patines de cola de aviones caracterizada por el hecho de que las cámaras de aire de ambas ruedas están unidas entre sí por una tubería compensadora de presión.
Patent ES-179284-A1 (ES)
Title: MEJORAS INTRODUCIDAS EN LA FABRICACIoN DE APARATOS PULVERIZADORES
Filed: 1947-08-09
Abstract: Mejoras introducidas en la fabricación de aparatos pulverizadores caracterizadas porque dichos aparatos llevan una polongación del gorrón sobre el que se articula la palanca de accionamiento de la bomba pulverizadora que sirve para accionar simultáneamente la palanca motriz del mecanismo agitador.
Patent ES-184496-A1 (ES)
Title: UN PROCEDIMIENTO Y APARATO PARA LA OBTENCIoN DE CINC PARTIENDO DE COMPUESTOS DE DICHO METAL
IPC: C22B19/04
Filed: 1948-07-07
Abstract: Procedimiento y aparato para la obtención de cinc partiendo de compuestos de dicho metal caracterizándose el procedimiento porque en la reducción de compuestos de cinc en condiciones de fluidificación para obtener el metal citado se mantiene la masa desmenuzada sometida a reducción en forma de un lecho o capa de sección transversal horizontal creciente en dirección ascendente.
Patent ES-189043-A1 (ES)
Title: Un sistema de montaje y desmontaje rapido para cubos de bicicletas y similares
Filed: 1949-07-12
Abstract: Sistema de montaje y desmontaje rápido para cubos de bicicletas y similares] caracterizado porque un freno de desatornillado actúa sobre el casquillo no acoplado con la palanca; siendo constituido por un muelle helicoidal de fricción dispuesto en un alojamiento circular del casquillo alrededor del eje; y apoyándose este muelle por una parte contra el fondo del alojamiento circular y por otra contra la cabeza de un tornillo de regulación de la fricción por atornillado o desatornillado en el extremo del eje.
Patent ES-192914-A1 (ES)
Title: Un procedimiento para corregir el factor de potencia en las instalaciones de lamparas o tubos fluorescentes
Filed: 1950-05-03
Abstract: Procedimiento para corregir el factor de potencia en las instalaciones de lámparas o tubos fluorescentes que comprenden un transformador de tensión cuyo primario está conectado a la. línea caracterizado por unir por medio de un puente uno de los bornes del primario del. transformador con uno de los bornes del secundario y tomar la corriente para las lámparas o tubos del otro borne del secundario y de uno de los bornes del primaria intercalando además en la instalación uno o varios condensadores de reducida capacidad.
Patent ES-195975-A1 (ES)
Title: Sembradora perfeccionada
Filed: 1950-12-29
Abstract: Sembradora perfeccionada caracterizada por un depósito para las semillas dividido en dos compartimientos el cual va unido a un chasis y con un tabique separador con pieza de madera y regletas distribuidoras con las que se puede sembrar a un mismo tiempo dos clases de semillas en perfecta regularidad y en forma alterna perfectamente distanciadas unas de otras.
Patent ES-196886-A1 (ES)
Title: PERFECCIONAMIENTOS EN LAS MáQUINAS PARA MONTAR CALZADO CON ALAMBRE
Filed: 1951-02-21
Abstract: Perfeccionamientos en las máquinas para montar calzado con alambre que se caracterizan por dotarlas de un dispositivo para graduar a voluntad el avance del alambre que penetra. en la máquina. para formar las grapas y de un dispositivo a doble cremallera invertida con piñón central único para graduar a voluntad la longitud total de la grapa acercando o separando sincronicamente sus extremos en forma simétrica y equidistante respecto al eje del punzón central que forma la grapa.
Patent ES-268414-A1 (ES)
Title: New stilbene-naphthotriazoles and their use as brighteners for fine fabrics
IPC: C07D/
Filed: 1961-06-20
Abstract: Compounds of formula <FORM:0917880/IV(a)/1> wherein R1 and R2 are hydrogen, chlorine or bromine atoms or alkyl or alkoxy groups containing 1-4 carbon atoms (see Group IV(b)) are used as optical brightening agents in polyamides, polyesters and polyurethanes. In an example the compound of formula <FORM:0917880/IV(a)/2> is added to the intermediate low molecular weight polymer obtained during the polymerization of dimethyl terephthalate and ethylene glycol. The final polymer is obtained and formed into fibres in the usual manner.ALSO:The invention comprises compounds of formula:-<FORM:0917880/IV (b)/1> wherein R1 and R2 are hydrogen, chlorine or bromine atoms or alkyl or alkoxy groups containing 1-4 carbon atoms. They are used as optical brightening agents (see Groups IV(a) and IV(c)). The compounds are prepared by diazotising a suitable 4-amino-2-carbamylstilbene coupling the diazo compound with 2-naphthylamine and oxidising the o-amino-azo compound. In an example 5-nitro-o-tolunitrile and p-chlorobenzaldehyde are condensed in glacial acetic acid and the product saponified with aqueous caustic soda to give 4-nitro-2-carbamyl-41-chloro-stilbene which is reduced to the 4-amino compound. The diazo compound of the amine is coupled with 2-naphthylamine and the amino-azo compound heated in picoline in the presence of copper sulphate to give the compound of formula <FORM:0917880/IV (b)/2> The following compounds are similarly prepared <FORM:0917880/IV (b)/3>ALSO:Compounds of the formula <FORM:0917880/IV (b)/1> wherein R1 and R2 are hydrogen, chlorine or bromine atoms or alkyl or alkoxy groups containing 1-4 carbon atoms (see Group IV(b)), are used as brightening agents on films, fibres and fabrics made from polyesters, polyamides, polyvinyl chloride, polyvinylidene chloride, polystyrene, polyurethanes and polyethylene. In examples, polyamide and polyester fabrics are treated in aqueous baths containing brighteners of the above formula dissolved in dimethyl formamide.
Patent ES-275003-A1 (ES)
Title: Process for the manufacture of fluorubines
IPC: C09B/
Filed: 1962-02-27
Abstract: Fluorubines are made by heating a 2:3-diamoniquinoxaline of the formula:- <FORM:0935630/IV(a)/1> where A is an arylene residue, to bring about the splitting off of ammonia. Quinoxalines specified wherein A is an anthraquinone, anthracene, naphthalene or benzene residue or a benzene residue substituted by chloro-, methylor methoxyradicals. Substances which lower the melting-point such as benzoic or naphthoic acid, zinc chloride or inert organt solvents such as nitrobenzene, trichlorobenzene or dimethylformamide may be present during the heating. Examples are given. The products are pigments which colour polyamides in yellow shades. Those containing a vattable residue may be used as vat dyes.
Patent ES-297884-A1 (ES)
Title: Fluid pressure system and control valve
IPC: F16K31/143
Filed: 1964-03-21
Abstract: A valve for use in a vehicle braking system has a casing 10 with an inlet 12, outlet 14 and an exhaust port 16, the casing housing a plunger 20 with a ring seal 22 and the plunger having a closure member 28 secured thereto by a bolt 32 a depending guide tube 34 causes a slow upward motion of the plunger to eliminate the impact of another valve closure 38 on its seat 42, and gradually release air from the spring actuator 18 connected to the outlet 14. Closures 28, 38 have seat engaging beads 35, 40, respectively. The closure 38 incorporates a skirt 46 which serves as a check valve, whilst a spacer 50 separates the two closures, the chamber between which is open to the outlet 14. The plunger 20 is spring-loaded and has an operating knob 56. In the brake release position shown, the effective area defined by the bead 40 is less than that of the seal 22 so that inlet pressure maintains the valve in the illustrated portion with the outlet 14 open to exhaust. The valve may be moved manually to connect the outlet 14 to the inlet 12 the effective area of bead 35 is the same as that of the skirt 46 so when the closure 28 is seated the pressure in the outlet 14 acts in both the skirt 46, to urge it outwardly into sealing contact with the body 10, and on the closure 28 whereby the valve is balanced. Any drop in inlet pressure below the given minimum causes the closure 28 to unseat, this pressure multiplied by the area difference between chamber 26 and 19 produces a force which balances that of the loading spring.
Patent ES-336007-A1 (ES)
Title: Ozone-resistant composition
IPC: C08L9/00
Filed: 1967-01-24
Abstract: A composition comprises (1) a conjugated diene elastomer, (2) a 1-alkene copolymer elastomer, and (3) 6-ethoxy-1,2-dihydro-2,2,4-trimethyl quinoline or an N,N1-disubstituted p-phenylene diamine of the formula <FORM:1101240/C3/1> wherein R1 is phenyl, cyclohexyl or a C4-C8 branched alkyl group and R2 is cyclohexyl or a C4-C8 branched alkyl group, said compounds (2) and (3) being present together in an amount sufficient to resist attack by ozone on the conjugated diene elatomer.
Patent ES-337176-A1 (ES)
Title: Polymerization of vinyl chloride
IPC: C08F14/06
Filed: 1967-02-22
Abstract: Vinyl chloride is polymerized in bulk at - 15 DEG to 35 DEG C. in the presence, as catalyst, of an alpha-halo-lauroyl peroxide of the formula R-C(XY)-CO-O-O-CO-C(XY)-R where X and Y are respectively hydrogen and halogen or are both halogen and R is a n-decyl radical or halogenated derivative thereof. Homopolymers or copolymers with vinyl acetate, laurate, or stearate, 1,1-or 1,2-dichloroethylene, trichloroethylene, propenylchloride, chlorotrifluoroethylene, chloroprene or acrylonitrile can be prepared. There may optionally be added molecular oxygen and a reducing agent to form a redox system, e.g. triethylboron hydrazine. In terms of active oxygen, the catalyst is used in proportions of 0.001-0.012% of the monomer(s). Unreacted monomer is removed after stopping the polymerization.
Patent ES-339358-A1 (ES)
Title: Apparatus and process for the continuous production of foamed glass and foamed ceramic
IPC: C03B19/06
Filed: 1967-04-15
Abstract: Foamed or sintered mouldings of ceramic or vitreous materials are produced by mixing pulverulent or granular materials, e.g. expandable clay or foamable porcelain, and necessary additives or insertions and depositing the mixture on an endless lower metal band which is moved through a muffle furnace having a cross-section, defined by muffles, which determines the cross-section of the product, wherein the mixture is treated first at foaming or sintering temperatures above about 500 DEG C. and then in one or more cooling zones. There is also an upper metal band moving through the furnace. A multi-layer product may be formed by depositing several different starting materials on the band consecutively, filler and reinforcing fabrics such as steel wool, being simultaneously introduced into or under the starting material, if required. The continuously emerging material may be cut into lengths, the saw being initiated by a limit switch on leaving the furnace or after cooling. The cross-section of the product may be varied by changing the dimensions of the furnace. The metal bands are lubricated as by talc, and cooled towards the end of the furnace.
Patent ES-339394-A1 (ES)
Title: Novel halo-substituted tetrahydro-quinazolines
IPC: D01G21/00
Filed: 1967-04-17
Abstract: Novel 1,2,3,4 - tetrahydroquinazoline derivatives of the general formula wherein Hal represents a chlorine or bromine atom R1 represents a hydrogen, chlorine or bromine atom R2 represents a straight or branched chain C 1 -C 5 alkyl group, a hydroxyalkyl, alkoxyalkyl, dialkylamino, cycloalkyl, hydroxycycloalkyl, pyridalkyl or aralkyl group and R3 represents a hydrogen atom, an alkyl or an aryl group and physiologically compatible acid addition salts thereof are prepared (a) when R3 represents a hydrogen atom, by reaction of a 2-amino-benzylamine derivative of the formula with formaldehyde, (b) by reduction of a quinazoline derivative of the formula wherein X represents two hydrogen atoms or an oxygen atom with a metal hydride (c) when R3 represents a hydrogen atom or an alkyl group and R1 is a chlorine or bromine atom, by chlorination or bromination of a 1,2,3,4-tetrahydroquinazoline of the formula wherein R3 represents a hydrogen atom or an alkyl group or (d) when R5 is a hydrogen atom, by reduction of a 1,2,3,4, - tetrahydroquinazolone-(2) of the formula with a metal hydride followed by optional conversion to a physiologically compatible acid addition salt of the product. Pharmaceutical compositions having antipyretic, anti-tussive and secretolytic activity comprise as active ingredient at least one 1,2,3,4 - tetrahydroquinazoline derivative of the first general formula above or a physiologically compatible acid addition salt thereof in association with a pharmaceutical carrier or excipient. 1,2,3,4 - Tetrahydroquinazolones - (2) of the fifth formula above are prepred by reaction of 2-amino-benzyl-amines of the second formula above with phosgene.
Patent ES-340528-A1 (ES)
Title: Heat-Exchanger
IPC: F28F1/10
Filed: 1967-05-13
Abstract: A heat exchange element comprises two twisted hollow metal rods 1 and 2 having wires 4 constituting fins disposed in planes perpendicular to the axis of the rods and arranged in a spiral path extending longitudinally along the rods. Such an element may be incorporated in various heat exchange assemblies (see Figs. 2-9). The heat exchanger may consist of one (Fig. 2) or a plurality (Fig. 3) of such elements disposed within a tubular casing wherein the wires 4 are arranged to contact both the casing wall and the wires of adjacent elements. As shown, in Fig. 4, a tube 14 containing elements 12a, 12b is disposed concentrically within a casing 18 containing further elements 16 so defining a plurality of fluid flow ducts wherein more than two fluids may exchange heat simultaneously. The spirals of the elements 12a, 12b preferably have opposite pitches. Additional tubes may be arranged either concentrically around the tube 18 (Fig. 6) or be disposed in spaced relationship within the tube 18 (Fig. 5). A tubular casing (30, Fig. 7), e.g. in the form of a coil and carrying two elements (31) may be immersed in a liquid further elements may be attached to the outer casing (Fig. 8). In another embodiment (Fig. 9) a plurality of elements may be attached to a solid heating conducting mass which is immersed in a liquid.
Patent ES-342485-A1 (ES)
Title: Manufacture of sodium phosphate
IPC: C01B25/30
Filed: 1967-06-30
Abstract: Sodium phosphate is manufactured by reacting phosphate rock (4CaO.P 2 O 5 ) with H 3 PO 4 or H 2 SO 4 or a mixture thereof, in the presence of sodium sulphate and at a temperature of 50- 95 C. the mineral acid being used in a concentration equivalent to at least 38% P 2 O 5 . The sodium phosphate solution produced has a low SO 4 = content while the CaSO 4 .H 2 O (hemihydrate) which precipitates out is separated from the solution by filtration. Preferred mineral acid concentration corresponds to 38-40% P 2 O 5 while the temperature range is 55-80 C. 75% of ground Moroccan phosphate rock and 32À7% Na 2 SO 4 (powdered) are used as solid mixture reacted upon by 39% P 2 O 5 as H 3 PO 4 having free SO 4 = content of 1À8 gm./ 100 gm. P 2 O 5 at 60 C. in some examples. The SO 4 = content of the filtered solution was 0À96 gm./100 gm. P 2 O 5 .
Patent ES-345690-A1 (ES)
Title: 2-aminomethyl benzofuran derivatives
IPC: C07D307/81
Filed: 1967-10-03
Abstract: The invention comprises compounds of formula and their pharmaceutically acceptable acid addition salts, wherein R 1 is 2-, 3- or 4-pyridyl, 3- or 4-methoxyphenyl, 3- or 4-chlorophenyl, or 3- or 4-tolyl R 2 is Et, Pr or Me 2 CH substituted by an Me 2 N, Et 2 N, piperidino, N-methylpiperazino, N - (2 - Me 2 NC 2 H 4 -)-piperazino or N-(3-Me 2 NC 3 H 6 -)-piperazino R 3 is H or Me R 4 is H, Cl or piperidinomethyl and R 5 is H, or when R 3 is H and R 4 is not Cl, R 5 may be H or MeO. These compounds are prepared by reacting either the alkali metal salt of A-CH 2 - NH-R 1 with R 2 Cl or R 2 Br, or A-CH 2 Cl with NHR 1 R 2 , A being the benzofuran residue shown. Antitussive and antihistaminic compositions for oral or parenteral administration comprise the above compounds with pharmaceutical carriers.
Patent ES-346194-A1 (ES)
Title: 1-(5-nitrofurfurylideneamino)-3-nitroso-2-imidazolidinone
IPC: A61K31/415
Filed: 1967-10-18
Abstract: The novel compound 1-(5-nitrofurfurylideneamino) - 3 - nitroso - 2 - imidazolidinone is prepared by nitrosating 1-(5-nitrofurfurylideneamino)-2-imidazolidinone. Antibacterial compositions comprise the novel compound together with a carrier or diluent. The compositions may be in the form of solutions, suspensions, sprays, dusts and ointments.
Patent ES-361348-A1 (ES)
Title: Process for preparation of peresters from organo-peroxyborates
IPC: C07C409/38
Filed: 1968-12-12
Abstract: Peresters of carboxylic acids are obtained by reacting the appropriate carboxylic acids with organo-peroxyborates, e.g. ortho- or metaperoxyborates of the Formul[mu] I and II respectively, wherein each of R 1 , R 2 and R 3 is a hydrogen atom or a group -R or -OR, R being an optionally substituted alkyl, alkenyl, cycloalkyl, cycloalkenyl, aralkyl, aralkenyl, or aryl group, provided that at least one of them is an OR group. The ortho-peroxyborate starting materials of the above formula may be obtained by reacting organic hydroperoxides with alkoxyboranes (e.g. trimethyl borate), boric acid or boron oxide.
Patent ES-367145-A1 (ES)
Title: 2-benzoxazolyl n-methyl-n-naphthyl-dithiocarbamate
IPC: C07D263/58
Filed: 1969-05-12
Abstract: A novel, therapeutic dithiocarbamate (I) is obtained by reacting a salt of 2-mercaptobenzoxazole with an N - methyl - N - naphth- 1-ylthiocarbamic acid halide (e.g. the chloride which is prepared by the interaction of thiophosgene and N-methyl-[alpha]-naphthylamine) or by reacting N-methyl-[alpha]-naphthylamine with a benzoxazol-2-yldithiocarbonic acid halide.
Patent ES-389409-A1 (ES)
Title: Air cushion seismic vibrator
IPC: G01V1/133
Filed: 1971-03-08
Abstract: A seismic vibrator is designed for use over all kinds of terrain including marshy areas where conventional land or sea vibrators cannot be used. The vibrator is an air cushion vehicle modified by the addition of an air flow modulator which pressure modulates the air cushion. The pressure modulations are passed on to the material beneath the vehicle.
Patent ES-393840-A1 (ES)
Title: Anhydrous hydrogen peroxide solutions
IPC: C01B15/017
Filed: 1971-07-31
Abstract: Anhydrous solutions of hydrogen peroxide, containing about 3 to 60 percent by weight of H2O2 in a saturated nitrogen heterocyclic compound having 4 to 6 ring members and a carbonyl group adjacent to the nitrogen atom are obtained by adding the heterocyclic compound to an aqueous solution of hydrogen peroxide and removing the water, as by distillation. The heterocyclic compound is a lactam or N-acylated structure, N-methyl-pyrrolidone being preferred.
Patent ES-407671-A1 (ES)
Title: Camera positioning apparatus
IPC: B01J13/16
Filed: 1972-10-16
Abstract: Apparatus including a camera preferably having a fixed focus lens adapted to be directed toward an object to be photographed, with the camera carrying a structure which projects generally toward the object and mounts a focus indicator for indicating to a user the location of a predetermined plane in which a photographic object may be positioned for proper focusing of its image on the camera film. A positioning unit projects beyond the focus indicator for engagement with a support, and is adjustable to vary the spacing of the focus indicator from the support.