baber/WOPTO huggingface dataset:
Patent CA-3118031-A1 (CA)
Title: Synthese du (s)-6-hydroxy-tryptophane et de derives de celui-ci
Inventor: SIMON WERNER
IPC: C07D209/20
Filed: 2019-12-11
Abstract: La présente invention concerne de nouveaux procédés et composés pour synthétiser des dérivés d'amanitine. L'invention concerne en particulier des procédés de synthèse de dérivés du (S)-6-hydroxy-tryptophane qui peuvent être utilisés en tant que synthons pour synthétiser des dérivés d'amanitine ou des conjugués médicamenteux d'amatoxine. L'invention concerne en outre des composés intermédiaires desdites voies de synthèse destinés à être utilisés dans la synthèse de dérivés d'amanitine et de conjugués médicamenteux d'amatoxine et l'utilisation de catalyseurs particuliers appropriés pour la médiation desdites voies de synthèse.
Patent CA-3118829-A1 (CA)
Title: Pivot hinge
Inventor: MITCHELL BRETT
IPC: F25D23/00
Filed: 2021-05-17
Abstract: A pivot hinge includes a spring housing with a central tube, a spring assembly, an upper mounting plate, and a lower mounting plate. The bottom end includes a knurled outer surface. A stop cam is positioned about the knurled outer surface and has an inner surface that conform to the knurled outer surface so that it may be positioned in a plurality of rotatable positions relative to the central tube. The stop cam also has an exterior surface which includes a detent. The different rotational positions of the stop cam upon the knurled outer surface changes the relative position of the detent in relationship to the central tube. A cam follower assembly is coupled to the lower mounting plate and has a cam follower plate with a cam follower that rides upon the stop cam and engages the detent recess to hold the door in an open position.
Patent CA-3127003-A1 (CA)
Title: Joint rotation stop structures for articulated support arms
Inventor: BORLOZ PAUL RENE
IPC: F16M11/08
Filed: 2020-02-28
Abstract: Improved support structures and systems are disclosed for installing tablet devices, display screens, flat screen monitors, or medical devices within a wide variety of environments. A core arm extends from a rear end, toward a front end, in which the rear end is configured to be pivotably mounted either directly to a mount structure, or to an extension arm that in turn is mounted to a mount structure. The front end is configured to be pivotably mounted to a front-end panel mount structure. The structures and systems can be configured for light or heavy configurations, with or without the use of an extension arm, and can provide fully concealed cable routing, in which one or more cables are readily accessible, via snap fit covers, for easy installation and maintenance, which can provide a clean structure that can readily be serviced and cleaned as desired.
Patent CA-3128660-A1 (CA)
Title: Compositions and methods for the prevention and/or treatment of covid-19
Inventor: MARCUSSON ERIC G
IPC: A61P37/04
Filed: 2021-08-19
Abstract: The present disclosure relates to compositions and methods for the preparation, manufacture and therapeutic use of nucleic acid vaccines comprising polynucleotide sequences encoding one or more structural proteins of SARS-CoV-2 and variants for the treatment and/or prevention of COVID-19.
Patent CA-3131274-A1 (CA)
Inventor: BELLOS MICHAEL
IPC: G02B5/22
Filed: 2020-03-03
Abstract: Apparatus and methods relating to attenuating excitation radiation incident on a sensor (1-122) in an integrated device that is used for sample analysis are described. At least one semiconductor film (1-336) of a selected material and crystal morphology is located between a waveguide (1-115) and a sensor (1-122) in an integrated device that is formed on a substrate (1-105). Rejection ratios greater than 100 or more can be obtained for excitation and emission wavelengths that are 40 nm apart for a single layer of semiconductor material (1-135).
Patent CA-3131411-A1 (CA)
Inventor: LI SHUZHEN
IPC: G06T1/00
Filed: 2019-03-12
Abstract: Methods and systems for tracking image senders using client devices are described herein. A computing system may receive an image containing a first watermark vector corresponding to a user account of an image sender. The computing system may convert the image to a frequency domain image that contains the first watermark vector. From the frequency domain image, the computing system may identify the first watermark vector. The computing system may compare the first watermark vector to each of a plurality of stored watermark vectors, each corresponding to a known user account, to determine a probability of a match. The computing system may determine the user account of the sender of the image by determining which of the plurality of stored watermark vectors has a highest probability of a match, and may send, to a workplace administrator platform, an indication of the user account.
Patent CA-3131530-A1 (CA)
Inventor: PENG SHENG
IPC: C07C17/354
Filed: 2020-04-03
Abstract: Processes for producing Z-1,1,1,4,4,4-hexafluorobut-2-ene and intermediates for producing same. A process for producing 2-chloro-1,1,1,4,4,4-hexafluorobutane comprises contacting 1,1,2,4,4-pentachlorobuta-1,3-diene with HF in the liquid phase in the presence of a fluorination catalyst. A process for producing 2,2-dichloro-1,1,1,4,4,4-hexafluorobutane comprises contacting 2-chloro-1,1,1,4,4,4-hexafluorobutane with a chlorine source. A process for producing 1,1,1,4,4,4-hexafluoro-2-butyne comprises contacting 2,2-dichloro-1,1,1,4,4,4-hexafluorobutane with a base. A process for producing Z-1,1,1,4,4,4-hexafluorobut-2-ene comprises contacting 1,1,1,4,4,4-hexafluoro-2-butyne with hydrogen.
Patent CA-3132685-A1 (CA)
Title: A neural-network-driven topology for optical coherence tomography segmentation
Inventor: HE YUFAN
IPC: G06N3/08
Filed: 2020-03-25
Abstract: A device receives a two-dimensional (2-D) image that depicts a cross-sectional view of a macula comprised of layers and boundaries to segment the layers, and determines spatial coordinates of the 2-D image that include x-coordinates and y-coordinates. The device uses a data model, that has been trained using a deep learning technique, to process the 2-D image and the spatial coordinates to generate boundary maps that indicate likelihoods of voxels of the 2-D image being in positions that are part of particular boundaries. The device determines, by analyzing the boundary maps, an initial set of boundary positions, and determines a final set of boundary positions by using a topological order identification technique to refine the initial set of boundary positions. The device determines thickness levels of the layers of the macula based on the final set of boundary positions, and performs one or more actions based on the thickness levels.
Patent CA-3135553-A1 (CA)
Title: Amino acid compositions and uses thereof
Inventor: VIDYASAGAR SADASIVAN
IPC: A61P17/04
Filed: 2017-10-04
Abstract: The present disclosure provides compositions and methods for promoting stem cell and/or progenitor cell proliferation and/or differentiation. The provided compositions may be useful in treating a disease or condition that is related to mucosal barrier function, e.g., wound healing, treating skin conditions (e.g., atopic dermatitis, psoriasis, bed sores, or condition related to the aging of skin), treating a lung disorders (e.g., asthma), a condition related to improving mucosal barrier function, and/or treating injury to GI mucosa in a subject in need thereof. The present disclosure also provides methods for promoting the proliferation and/or differentiation of stem cells and/or the progenitor cells in a subject in need of such treatment by administering a composition. The ability to stimulate the proliferation and/or differentiation of stem cells and/or the progenitor cells in vivo, ex vivo and/or in vitro provides tremendous benefit. The present disclosure can be used to increase stem cell populations in in vivo, ex vivo and/or in vitro. Stem cell transplantation provides treatments and/or cures of many disease states, degeneration and/or injury.
Patent CA-3135869-A1 (CA)
Inventor: WALKER ADAM
IPC: C08B1/00
Filed: 2020-05-01
Abstract: The present invention provides a process for separating cellulose from a feedstock, comprising the steps of: a) wetting the cellulose with a first solvent system to form wet cellulose; b) contacting the wet cellulose with a second solvent system to form a mixture; c) maintaining the mixture at a first temperature for a first period of time; d) maintaining the mixture at a second temperature for a second period of time to dissolve the cellulose; and e) removing the first and second solvent system containing the dissolved cellulose.
Patent CA-3137603-A1 (CA)
Title: High speed high performance delineator system
Inventor: HANNAH GREGORY
IPC: E01F9/658
Filed: 2020-05-19
Abstract: A traffic delineator system having a flexible delineator body member, a base member, a cylindrical load-collar attached to the body member at a first end and having a second end with rigid tapering threaded shoulder members to be releasably interlocked within a receiving space in the base member. The collar has tapering side walls with a varying thickness from a first end to a second end.
Patent CA-3137651-A1 (CA)
Inventor: GERWE DAVID RODERICK
IPC: G01C11/02
Filed: 2021-11-04
Abstract: A combined multi-spectral and polarization (CMSP) sensor is disclosed that enhances contrast-to-noise ratio (CNR). The CMSP sensor comprises a multi-spectral and polarization (MSP) filter, a single focal plane array (FPA), and a controller.  The FPA  comprises a plurality of detectors and the MSP filter comprises at least a first bandpass filter having a first frequency range and a second bandpass filter having a second frequency range that is distinct from the first frequency range and a first polarization filter having a first polarization value and a second polarization filter having a second polarization value that is distinct from the first polarization value.
Patent CA-3139964-A1 (CA)
Title: System and method for performing equality and less than operations on encrypted data with quasigroup operations
Inventor: KOLTE PRIYADARSHAN
IPC: G06F21/60
Filed: 2020-05-07
Abstract: An encryption system and method that addresses private computation in public clouds and provides the ability to perform operations of encrypted data (including equality determinations and compare for less than operations) are provided.
Patent CA-3141527-A1 (CA)
Title: Composition for the treatment of muscle wasting
Inventor: ALLEGRETTI MARCELLO
IPC: A61P21/00
Filed: 2020-06-29
Abstract: The present invention relates to compositions comprising branched-chain amino acids (BCAA) and the amino acid L-Alanine and their use in the prevention and/or treatment of muscle wasting associated to pathological or age-related conditions.
Patent CA-3143798-A1 (CA)
Title: Access door for a storage unit
Inventor: KUTER-ARNEBECK OTTOLEO
IPC: A47B55/00
Filed: 2021-12-23
Abstract: A storage unit having an interior containment space. The storage unit includes a connection member, an access door coupled to the storage unit via a hinge and adapted to cover at least a portion of the interior containment space, and a biasing member having opposing first and second ends. The first end is coupled to the access door, and the second end is releasably coupled to the connection member. The second end is adapted to be released from the connection member when the access door is overextended or opened with too great a force.
Patent CA-3144924-A1 (CA)
Title: Cable d'attache d'equipement
Inventor: BESSAC GRANT DENTON
IPC: B65H75/40
Filed: 2018-01-22
Abstract: Un cordon d'attache d'équipement comprend un carter, une bobine située dans le carter, un cordon enroulé autour de la bobine, un élément de contrainte de bobine couplé à la bobine, un verrou de mousqueton, et un mousqueton couplé au câble. Le carter définit une ouverture pour cordon dans laquelle le cordon peut passer. La bobine peut tourner sur un axe de bobine dans un sens de bobinage ou de débobinage. L'élément de contrainte de bobine applique une force à la bobine pour la faire tourner dans le sens de débobinage de façon à rétracter le cordon. Le verrou de mousqueton comprend une protubérance pouvant passer d'une position rétractée à une position déployée pour libérer le mousqueton du verrou de mousqueton. Le mousqueton couple de façon sélective le cordon d'attache à un autre objet. Un opérateur peut utiliser le câble d'attache d'équipement pour y attacher un objet (p. ex., un couteau) de façon à pouvoir accéder à cet objet en cas de besoin.
Patent CA-3145873-A1 (CA)
Title: Systemes d'attache de sangle, attaches rapides et systemes et procedes associes
Inventor: BUGEAUD JASON P
IPC: A63B21/055
Filed: 2020-07-02
Abstract: L'invention concerne un système d'attache rapide mâle-femelle, ainsi que des procédés et des utilisations associés. Des exemples d'applications comprennent l'utilisation de la sangle en tant que bande de résistance pour exercice physique, attache d'amarrage nautique, dispositifs de retenue de remplacement ou complémentaires pour le transport de fret, et autres. L'invention concerne un système d'attache de sangle interchangeable, comprenant : une attache mâle ; une sangle reliée à l'attache mâle ; une pluralité d'embouts femelles espacés les uns des autres et fixés à un substrat, chaque embout femelle présentant une structure permettant à l'attache mâle de s'attacher rapidement à l'embout femelle et de s'en détacher tout aussi rapidement et ce, de manière interchangeable.
Patent CA-3146844-A1 (CA)
Title: Relachement de fin de course dans un systeme de direction assistee
Inventor: TIPTON JEFFREY
IPC: B62D5/06
Filed: 2020-07-10
Abstract: La présente invention concerne un ensemble direction assistée amélioré. L'ensemble direction assistée comprend un mécanisme de fin de course et une cartouche de soupape qui est actionnée par des anneaux d'actionneur gauche et droit du mécanisme de fin de course, les anneaux d'actionneur s'étendant partiellement autour d'un arbre de sortie. Les anneaux d'actionneur peuvent être réglés individuellement pour le relâchement de fin de course souhaité pour limiter la pression de système maximale lorsque l'ensemble direction approche du réglage d'arrêt d'essieu souhaité. La cartouche de soupape fournit une fonction de fin de course et une fonction de relâchement de pression et est en communication fluidique avec les chambres de pression gauche et droite pour faire recirculer un fluide hydraulique en cas de condition de mise hors tension.
Patent CA-3149120-A1 (CA)
Title: Treatment of sebaceous gland disorders
Inventor: VERBAKEL JOOST
IPC: A61K31/357
Filed: 2020-07-29
Abstract: The present invention provides a topical formulation for use in a method of treating or preventing a sebaceous gland disorder selected from acne, seborrhea, rosacea, perioral dermatitis, corticosteroid-induced acneiform lesions and oily skin and/or for use in a method of inhibiting growth of Priopionibacterium Acnes, said method comprising topically administrating a formulation comprising (i) cannabidiol and (ii) triterpenes selected from asiaticoside, madecassoside, asiatic acid, madecassic acid and combinations thereof. The invention further relates to a topical formulation comprising:  cannabidiol;  triterpenes selected from asiaticoside, madecassoside, asiatic acid, madecassic acid and combinations thereof;  flavonolignans selected silibinin, isosilibinin, silicristin, silidianin and combinations thereof, the concentrations of these flavonolignans being calculated as silibinin.
Patent CA-3149827-A1 (CA)
Title: Cut-resistant multi-ply twisted yarns and fabrics
Inventor: HU YINGXIANG
IPC: D02G3/44
Filed: 2020-09-01
Abstract: The present invention provides a multi-ply twisted yarn for a cut- resistant fabric, and the multi-ply twisted yarn comprises (i) at least a first single yarn (1) having a skin-core structure, wherein the skin comprises aromatic polyamide staple fibers (11) and the core comprises tungsten filaments (12), and (ii) at least a second single yarn (2) having a skin-core structure, wherein the skin comprises cut- resistant staple fibers (21), the core comprises at least an elastomer filament (22), and the cut-resistant staple fibers of the second single yarn are selected from one or more of aromatic polyamide staple fibers, aliphatic polyamide staple fibers and polyethylene staple fibers. The present invention further provides a cut-resistant fabric comprising the multi-ply twisted yarn and a protective product comprising the cut-resistant fabric.
Patent CA-3155369-A1 (CA)
Inventor: DANEK MARIO
IPC: A24F40/10
Filed: 2020-10-20
Abstract: A liquid-filled cartridge for use with an electronic device for delivery of a substance into a body through respiration includes a liquid container; and a liquid contained within the container for aerosolizing and inhaling by a person using the electronic device. The liquid includes a plurality of nanoparticles in a nanoemulsion, the nanoparticles including the encapsulation of the substance to be delivered into the body through respiration. The nanoemulsion preferably is produced using a microfluidizing machine.
Patent CA-3158494-A1 (CA)
Inventor: GOETZ FLORIAN
IPC: B23B51/04
Filed: 2020-12-07
Abstract: The invention relates to an apparatus (10) for transmitting a torque from a drill device to a core bit, having an insertion end (14) and a tool holder (13). The insertion end (14) is composed of a first outer cone region, a groove region and a second outer cone region and has first longitudinal grooves and second longitudinal grooves. The tool holder (13) is composed of a main body (41), which has first outer rotary driving grooves, an intermediate element (42), which comprises first inner rotary drivers, second inner rotary drivers and first outer rotary drivers, and a locking device (43). In the connected state , the first inner rotary drivers engage the first longitudinal grooves, the second inner rotary drivers engage the second longitudinal grooves and the first outer rotary drivers engage the first outer rotary driving grooves.
Patent CA-3159008-A1 (CA)
Inventor: ZHANG RIKUI
IPC: F02C7/141
Filed: 2022-02-23
Abstract: A turbine engine gas-inlet cooling system and a turbine engine apparatus are provided.  The turbine engine has a gas-inlet end and a gas-outlet end, and the turbine engine gas-inlet cooling system includes a gas-inlet cooling device, the gas-inlet cooling device includes a gas-input end and a gas-output end, and is configured to cool working gas input from the gas-input end, and the gas-output end is connected with the gas-inlet end of the turbine engine.
Patent CA-3164693-A1 (CA)
Title: Human plasma kallikrein inhibitors
Inventor: KOTIAN PRAVIN L
IPC: C07D417/12
Filed: 2015-03-09
Abstract: Disclosed are compounds of formula (I), as described herein, and pharmaceutically acceptable salts thereof. The compounds are inhibitors of plasma kallikrein. Also provided are pharmaceutical compositions comprising at least one compound of the invention, and methods involving use of the compounds and compositions of the invention in the treatment and prevention of diseases and conditions characterized by unwanted plasma kallikrein activity.
Patent CA-3164768-A1 (CA)
Inventor: MA QINGLONG
IPC: G06F3/01
Filed: 2020-08-28
Abstract: L'invention concerne un dispositif et un procédé d'interaction homme-machine pour un appareil intelligent, permettant d'améliorer l'expérience d'utilisateur d'une interaction homme-machine. Le dispositif comprend une interface d'identification, une unité de modèle d'interaction, une unité d'identification d'intentions et une interface de commande. L'interface d'identification sert à lancer une demande d'identification en lien avec un canal d'identification. L'unité de modèle d'interaction comprend un dispositif de commande de canaux, un dispositif de commande de focalisation et un gestionnaire de politiques. Le dispositif de commande de focalisation sert à acquérir une logique de commande pour la demande d'identification selon une priorité en matière de politique d'identification de la demande d'identification. Le dispositif de commande de canaux sert à exécuter une action de commande sur la demande d'identification dans le canal d'identification selon la logique de commande, de façon à acquérir des données de tâche. L'unité d'identification d'intentions sert à identifier une instruction d'intention des données de tâche, de façon à générer une demande de commande, de sorte que le dispositif de commande de focalisation acquière la logique de commande pour la demande de commande selon une priorité en matière de politique de commande de la demande de commande. Le dispositif de commande de canaux sert en outre à agir sur la demande de commande dans le canal de commande selon la logique de commande, de façon à acquérir une action de comportement. L'interface de commande commande et délivre en sortie l'action de comportement.
Patent CA-3166735-A1 (CA)
Inventor: LI MENG
IPC: A61P1/06
Filed: 2021-01-04
Abstract: L'invention concerne l'utilisation d'inhibiteurs de PRMT5 tels que et comprenant (1S,2S,3S,5R)-3-((6-(difluorométhyl)-5-fluoro-1,2,3,4-tétrahydroisoquinolin-8-yl)oxy)-5-(4-méthyl-7H-pyrrolo[2,3-d]pyrimidin-7-yl)cyclopentane-1,2-diol: (I) ou un sel pharmaceutiquement acceptable de celui-ci, pour traiter le psoriasis, le lupus érythémateux disséminé (SLE), la polyarthrite rhumatoïde (RA), l'arthrite psoriasique et d'autres affections ou troubles auto-immuns.
Patent CA-3169473-A1 (CA)
Title: Acetate monohydrate sodique 2-[(4s)-8-fluoro-2-[4-(3-methoxyphenyl)) piperazin-1-yl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]-4h-quinazolin-4-yl], sa preparation et son utilisation
Inventor: BUSCHMANN HELMUT
IPC: A61P31/22
Filed: 2021-03-01
Abstract: La présente invention concerne le nouvel acétate monohydrate 3,4-dihydroquinazoline sodique 2-[(4S)-8-fluoro- 2-[4-(3-méthoxyphényl)pipérazin-1-yl]-3-[2-méthoxy-5-(trifluorométhyl)phényl]-4H-quinazoline-4-yl], des procédés pour sa préparation ainsi que des compositions pharmaceutiques contenant ladite 3,4-dihydroquinazoline. Ledit composé est particulièrement utile pour le traitement et la prévention de maladies associées au cytomégalovirus (CMV), en particulier le cytomégalovirus humain (HCMV).
Patent CA-3170652-A1 (CA)
Inventor: SATHE BALAJI DASHRATH
IPC: A61P35/00
Filed: 2021-02-17
Abstract: L'invention concerne de nouveaux composés de formule (1) : ou un sel de celui-ci, X, Y, R1, R2, R3, R4 et R5 étant tels que définis dans la description, et leur utilisation dans le traitement, la prévention, l'amélioration, le contrôle ou la réduction du risque de troubles associés à la kinase 2 non dépressible de régulation générale (GCN2).
Patent CA-3171028-A1 (CA)
Inventor: BECK TODD
IPC: A47B47/00
Filed: 2022-08-24
Abstract: The technology described herein includes a four-column shelving unit. One or more improved tie bars run between the front and rear shelf-support beams. The one or more tie bars are installed perpendicular to the shelf-support beams. The improved tie bar may take the overall fonn of a V-channel with a novel tri-notch connection on either end. The tri-notch connection allows the tie bar to connect with a front shelf-support beam on one end and a back shelf-support beam on the other end. The tri-notch connection includes two bottom notches and a top notch. The top notch may fonn a gap in the V-channel that allows the end of the tie bar to slip under a shelf-support flange on a shelf-support beam during installation. The two bottom notches are sized and shaped to receive an upward facing retention flange located on the bottom flange of the shelf-support beam.