baber/WOPTO huggingface dataset:
Patent AT-E233593-T1 (AT)
Inventor: MUTTERER JAMES NELSON JR
IPC: B01J19/12
Filed: 1999-04-20
Granted: 2003-03-15
Abstract: A system for carrying out microwave assisted chemical reactions is disclosed. The system includes a source of microwave radiation; a cavity in communication with the source, an attenuator in communication with the cavity for providing access to the cavity while preventing microwaves from escaping through the attenuator, and a vessel positioned in the cavity and the attenuator and extending externally of the attenuator for holding materials in the cavity while microwaves from the source are applied thereto. The vessel includes a reaction chamber and a venting portion. The chamber portion is positioned entirely within the cavity, and the venting portion extends from the cavity and through the attenuator and externally of the attenuator and has a gas passage for permitting gases to flow to or from the reaction portion from gas sources external to the cavity, the attenuator, and the vessel.
Patent AT-E325196-T1 (AT)
Inventor: NIELSEN JENS
IPC: C12N9/00
Filed: 1999-07-12
Granted: 2006-06-15
Abstract: A recombinant microbial cell comprises at least one increased expressible enzyme activity controlling anabolic metabolism of ammonia as a nutrient source, the increased enzyme activity being an NADH-dependent activity catalysing the reaction (a) 2-oxoglutarate+NH<SUB>3</SUB>+NADH->glutamate+NAD or being an activity catalysing the reaction (b) 2-oxoglutarate+glutamine+NADH->2 glutamate+NAD or being an activity catalysing the reaction (c) glutamate+NH<SUB>3</SUB>+ATP->glutamine+ADP+Pi. The increased enzyme activity is encoded by a nucleic acid coding sequence linked to an expression signal not natively associated with the nucleic acid coding sequence and is increased as compared to the expression of the enzyme activity when the nucleic acid coding sequence is associated with its native expression signal.
Patent AT-E269204-T1 (AT)
Inventor: MURPHY JAMES C
IPC: B29C49/04
Filed: 1999-09-13
Granted: 2004-07-15
Abstract: A process for fabricating a composite vessel includes: A) preforming a composite shell (63) for the vessel (by, for example, winding fiberglass and a thermoplastic material onto a thermoplastic mandrel), the shell having at least one opening for access to the interior; B) introducing an inflatable liner (66) fabricated from a thermoplastic film (67) into the composite shell through the opening; C) surrounding the composite shell with an outer thermoplastic film; D) in a mold (60) (which may optionally itself be heated), heating the thermoplastic film liner, the composite shell and the outer thermoplastic film while applying at least one force (e.g., by evacuating the mold, pressurizing the interior of the thermoplastic film liner or both) which tends to urge the thermoplastic film liner, the composite shell and the outer thermoplastic film outwardly; E) continuing step D) until the thermoplastic film liner, the composite shell and the outer thermoplastic film consolidate and the resulting composite structure becomes fluid and flows to conform to the interior surface of the mold, thereby forming the composite vessel; F) allowing the formed composite vessel to cool; and G) removing the formed composite vessel from the mold. The resulting composite vessel exhibits superior mechanical and aesthetic properties.
Patent AT-E541962-T1 (AT)
Inventor: SHATROV ALEXANDR SERGEEVICH
IPC: C25D11/18
Filed: 1999-08-17
Granted: 2012-02-15
Abstract: A protective multi-functional composite coating on non-ferrous alloys (Al, Mg, Ti, Nb, Al-Ti, Al-Be, Ti-Nb), consisting of a strong, hard, porous oxide-ceramic layer in the form of a matrix, and a functional compounds introduced into the pores of the matrix. The functional compounds are selected from a series of metals (Ni, Cu, Co, Fe, Cr, Mo, Ti, Al, Sb, Ag, Zn, Cd, Pb, Sn, Bi, In, Ga) and/or refractory compounds (carbides, oxides, nitrides, borides and silicides of the metals of groups IVB-VTB of the periodic system of elements). The oxide-ceramic matrix layer is applied by the oxidation of the base by the method of plasma electrolytic oxidation, and has high adhesion to the base. By regulating the parameters of the oxidation process, the required porosity of the oxide layer is achieved. The functional compounds are introduced into the porous structure of the ceramic matrix using any of the following processes: chemical or electrochemical precipitation from solutions, chemical or physical precipitation from the gaseous phase, or the friction-mechanical method (rubbing on). After the introduction of the functional compounds, the composite coating is subjected to finishing treatment with the aim of laying bare the apexes of the ceramic layer capable of taking load. The strongly developed surface of the porous structure of the matrix layer, bonded to the functional compound, creates a new coating with high cohesion strength. The composite coating acquires a combination of increased strength, hardness, wear and corrosion resistance, along with a certain plasticity and resistance to contact dynamic loads and vibrations.
Patent AT-E280198-T1 (AT)
Inventor: STIEBER JOSEPH F
IPC: C07D277/80
Filed: 1999-12-15
Granted: 2004-11-15
Abstract: A process is disclosed for preparing an N-hydrocarbyl-bis-benzothiazolesulfenamide comprising reacting an N-hydrocarbyl-2-benzothiazolesulfenamide with a cyclic organic acid anhydride in situ in a polymeric matrix at elevated temperature.
Patent AT-E234601-T1 (AT)
Inventor: SOLIMAN NADIA
IPC: A61K8/42
Filed: 1999-10-13
Granted: 2003-04-15
Abstract: An aqueous liquid composition comprising: (a) at least about 1 wt.% of a surfactant and mixtures thereof; (b) about 0.01 to about 2 wt.% of a material selected from the group consisting of vitamin E, vitamin C, vitamin A, a precursor of any of these said vitamins which is converted to the respective vitamin E, C and A when said precursor is contacted with skin, and mixtures thereof; and (c) about 0.5 to about 2 wt.% of an alkyl or alkenyl mono or di alcohol amide, said alkyl or alkenyl having from about 8 to about 20 carbon atoms, inclusive and said alcohol having from about one to three carbon atoms and mixtures thereof.
Patent AT-E268742-T1 (AT)
Inventor: HUFF CARL L
IPC: A62D3/00
Filed: 1999-10-27
Granted: 2004-06-15
Abstract: A method for treatment of heavy metal contaminated surface coatings, heavy metal contaminated industrial byproducts and industrial effluents utilizing calcium phosphate compounds to render the heavy metal compounds immobile and biologically nonhazardous to humans. In a first embodiment surfaces contaminated with heavy metal compounds are decontaminated in situ during their removal. Solid calcium phosphate material is added to the liquid or chemical paint remover before the paint remover is applied to the heavy metal contaminated painted surface. After application of the paint remover, it is removed by suitable means as scraping or water blasting. The paint and paint remover mixture thus removed is rendered non-toxic with the heavy metal compounds in the paint immobile and biologically nonhazardous. In a second embodiment of the invention, the calcium phosphate compounds are used in a floor sweeping compound to treat the heavy metal contaminated dust generated during industrial processes. Another embodiment uses the calcium phosphate compounds to treat the effluents of industrial furnaces and smelters and render the heavy metal compounds therein non-toxic. A fourth embodiment utilizes the calcium phosphate compounds in a finely ground form to be added to paint to produce a paint that can be applied over previously applied heavy metal contaminated paint to render the underlying heavy metal contaminated paint non-toxic. Other embodiments are shown as well.
Patent DE-02425414-T1 (DE)
Title: Sauger oder Schnuller
Inventor: TESTA MAURO
IPC: A61J11/00
Filed: 2002-06-24
Abstract: Sauger oder Schnuller mit einem Element aus flexiblem Material, welches in der Mundhöhle zu platzieren ist, und mit einem vergrößertem Kopf (1, 1') und einem länglichen Verbindungselement (2) zu einer Endkupplung (3, 3') für einen Nahrungsbehälter und/oder einem Plattenelement (4) eines Schnullers, dadurch gekennzeichnet, dass der vergrößerte Kopf (1, 1') und/oder das längliche Verbindungselement (2) vom Kopf zur Endkupplung (3, 3') für den Behälter oder die Platte (4) und/oder der Abschluss (3, 3') oder die Platte (4) selbst eine solche Form oder Aufbau haben, dass beim Saugen das natürliche Verhalten der Brustwarze und der Brust simuliert wird, zumindest bezüglich des Stimulationsvorgangs und dementsprechend richtigen Gebrauchs eines oder mehrerer Organe und/oder Gesichts-, Lippen- und/oder Zungenmuskeln, ähnlich der Stimulation und dementsprechend richtigem Gebrauch des mindestens einen oder der mehreren Organe oder Muskeln beim Saugen an der natürlichen Brust.
Patent DE-18707959-T1 (DE)
Title: Vorrichtung und verfahren zur erzeugung von mikroschaum
Inventor: NICMANIS MARK
IPC: B01F13/00
Filed: 2018-02-22
Abstract: Vorrichtung zur Erzeugung eines Mikroschaums, wobei die Vorrichtung einen Kanal mit einem Einlass und einem Auslass, eine Quelle für schäumbare Flüssigkeit und unter Druck stehendes Gas umfasst, die zum Einspeisen in den Einlass angeordnet ist, wobei der Kanal aus einem räumlich oszillierenden Strömungskanal besteht, um eine oszillierende Strömungsrichtung zu schaffen, wobei der räumlich oszillierende Strömungskanal um eine Hauptströmungsrichtung oszilliert, wobei der räumlich oszillierende Strömungskanal eine Sequenz von planaren Querschnitten senkrecht zur Strömungsrichtung mit einer Untersequenz von planaren Querschnitten, die senkrecht zur Hauptströmungsrichtung in der betreffenden Ebene sind, bereitstellt, wobei die Untersequenz mindestens eine Ebene umfasst, die sich nicht mit mindestens einer anderen Ebene in der Untersequenz überlappt.
Patent DE-34104-T1 (DE)
IPC: D03D47/06
Filed: 1981-01-30
Abstract: A process for making a woven ribbon having stitched selvages on a ribbon loom by moving a single weft inserting member crosswise in two directions. The weft inserting member inserts a first auxiliary thread along each selvage and alternately drives a second auxiliary thread in the opposite direction outside the selvage.
Patent DE-502928-T1 (DE)
Inventor: EYRE DAVID R
IPC: C12N5/20
Filed: 1990-11-30
Abstract: The invention provides assays and kits for measuring bone resorption by determining in a sample of body fluid the presence of concentration of a carboxy-terminal type I collagen telopeptide comprising:whereinis lysyl pyridinoline or hydroxylysyl pyridinoline.
Patent ES-2693085-T1 (ES)
Title: Uso de estriol en bajas dosis
Inventor: ACEBRON FERNANDEZ AIVARO
IPC: A61P15/02
Filed: 2008-06-25
Abstract: Uso de bajas dosis de estriol por vía vaginal para tratamiento y/o prevención de atrofia urogenital por déficit estrogénico en mujeres.
Patent ES-2347938-T1 (ES)
Title: Ración de alimento para animales y métodos para reducir los niveles de amoniaco y fósforo en el estiercol.
Inventor: HALE EDWARD
IPC: A23K10/38
Filed: 2008-08-20
Abstract: Ración de alimento para animales que comprende: un intercambiador de cationes sustancialmente indigestible, cuyo intercambiador de cationes incluye cationes de metales fosfato reactivos intercambiables, y dentro del cual dicho intercambiador de cationes se encuentra presente en una cantidad de hasta el 2,5% por peso y un material acidógeno, donde un animal alimentado con dicha ración produce un producto de desecho que incluye cationes de amonio ligados a dicho intercambiador de cationes.
Patent ES-2584190-T1 (ES)
Title: Proceso para la fabricación de una preparación farmacéutica que contiene acetato de glatiramero
Inventor: COHEN RAKEFET
IPC: A61K9/00
Filed: 2015-09-24
Abstract: Un proceso para preparar una preparación farmacéutica de acetato de glatiramero y manitol en un recipiente adecuado que comprende las etapas de: (i) obtener una solución farmacéutica acuosa de acetato de glatiramero y manitol; (ii) filtrar la solución farmacéutica acuosa a una temperatura por encima de 0 °C a 17,5 °C para producir un filtrado; y (iii) llenar el recipiente adecuado con el filtrado obtenido después de realizar la etapa (ii), para preparar así la preparación farmacéutica de acetato de glatiramero y manitol en el recipiente adecuado.
Patent ES-2049700-T1 (ES)
Inventor: ARGESE MARIA
IPC: A61K31/195
Filed: 1992-10-09
Abstract: S-carboxymethylcysteine lysine salt monohydrate <CHEM> for the preparation of a medicament having mucolytic, bronchosecretolytic and antibronchospastic activities, and a process for the preparation thereof, characterized in that L(R)-S-carboxymethylcysteine is reacted with a L(S)-lysine aqueous solution, the obtained solution is diluted with ethanol and the product is crystallized by stirring.
Patent ES-2105998-T1 (ES)
Inventor: SAIKI RANDY
IPC: C12Q1/68
Filed: 1987-08-21
Abstract: A stable enzyme composition is disclosed that comprises a thermostable nucleic acid polymerase enzyme in a buffer comprising non-ionic polymeric detergents.
Patent CY-1107636-T1 (CY)
Inventor: CRIPPS ALLAN WILLIAM
IPC: C12P21/08
Filed: 2007-05-22
Abstract: Novel antigens of  B. catarrhalis  are provided, together with their use in vaccines as well as methods of diagnosis and/or detection.
Patent CY-1108608-T1 (CY)
Inventor: STAFIEJ ANDRZEJ
IPC: A63B22/02
Filed: 2008-07-17
Abstract: A ski-exercising and rehabilitation apparatus of the invention wherein the down-hill-run unit (22), has a system of rotatable rolls (25) mounted with bearings in external clamping beams (20) and (21) and in the central beam (26) so that their rotation axes lie in one arched plane, whereas said central beam (26) is supported on its ends with shock absorbers (27), whereas the ends of external clamping beams (20 and 21) are jointed at one end with the shorter articulated connecting rods (18 and 19) of variable lengths and at the other end with the longer articulated connecting rods (23 and 24) of variable lengths, the other ends of which are rotatably connected with respective discs of the gear wheels (13, 14, 15 and 16) mounted on the front drive shaft (11) and rear drive shaft (12), said external clamping beams (20 and 21) being also jointed to rocking levers (34 and 35) which are connected to actuators (36) mounted in the frame base (1) of the apparatus, whereas the light signs (54), imitating the positions of slalom poles, are located on the track mat (30) of said downhill-run unit (22) in form of bristled track mat banding arcwise the upper drive roll (32) and lower drive roll (31).
Patent CY-1111624-T1 (CY)
Inventor: NEUHAUSER ALAN R
IPC: G10L19/018
Filed: 2011-02-09
Abstract: Systems and methods are provided for decoding a message symbol in an audio signal. This message symbol is represented by first and second code symbols displaced in time. Values representing the code signals are accumulated and the accumulated values are examined to detect the message symbol.
Patent CY-1111313-T1 (CY)
Inventor: MüLLER HANS RUDOLF
IPC: A23L33/15
Filed: 2011-03-03
Abstract: Crystalline salts of 5-methyl-(6R,S)-, -(6S)- and -(6R)-tetrahydrofolic acid are new. Independent claims are also included for: (1) crystalline calcium salt of 5-methyl-(6S)- and -(6R)-tetrahydrofolic acid; and (2) the preparation of crystalline salts of 5-methyl-(6R,S)-, -(6S)- and 5-methyl-(6R)-tetrahydrofolic acid.
Patent CY-1112337-T1 (CY)
Title: Καινοφανης ενωση αλφα-(ν-σουλφοναμιδο) ακεταμιδιου ως αναστολεας της παραγωγης του βητα αμυλοειδους πεπτιδιου
Inventor: STARRETT JR JOHN E
IPC: C07D271/06
Filed: 2011-06-15
Abstract: Η παρούσα εφεύρεση παρέχει καινοφανή ένωση άλφα-(Ν-σουλφοναμιδο)ακεταμιδίου, την φαρμακευτική σύνθεση αυτής, τις διεργασίες εξ αυτής και μέθοδο για την αγωγή της νόσου του Αλτσχάιμερ και άλλων καταστάσεων που συσχετίζονται με το β-αμυλοειδές πεπτίδιο.
Patent CY-1112928-T1 (CY)
Inventor: SVINDLAND ALF
IPC: E21B33/13
Filed: 2012-05-11
Abstract: The invention relates to a method to hinder/reduce the migration of formation fluids in wells, primarily in connection with plugging of oil wells. A mass of particulate matter consisting of naturally occurring and/or synthetically produced granular material, which may be suspended in a suitable liquid, is placed in or around the well casings (10, 12, 14 and 16) and production tubing (28) to form a plug. The particulate material mentioned can replace conventional mechanical plugs (40, 44, 48) and cement plugs (42, 46, 50). The particulate material plug (52) must have a sufficient length in the well, the particulate material must be suitably sorted and packed and have suitable chemical/physical properties, such that the permeability of the plug (52) becomes sufficiently small that the well is effectively plugged since the time required for formation fluids, e.g. oil, to migrate through the plug may be several thousand years. The plug of particulate matter (52) can also change in shape and adapt to possible geometry changes in the well, for example as a consequence of displacements in the Earth's crust or corrosion of metals in the well, and thereby hinder/minimise possible leaks.
Patent CY-1113143-T1 (CY)
Title: Μεθοδος προσδιορισμου της νοσου toy alzheimer
Inventor: HOLTZMAN DAVID M
IPC: G01N33/68
Filed: 2012-09-19
Abstract: Διαγνωστικό τεστ της προκλινικής ή κλινικής νόσου του Alzheimer που βασίζεται στα επίπεδα του Αβ40, Αβ42, την αναλογία τους ή το ρυθμό εισόδου αυτών μετά τη χορήγηση αντισωμάτων που απομονώνουν το Αβ. Μεταβολή οιασδήποτε από αυτές τις παραμέτρους από τις τιμές ελέγχου προσδιορίζει προκλινική ή κλινική νόσο του Alzheimer.
Patent CY-1115585-T1 (CY)
Title: Κρυσταλλικες μορφες του αλατος του νατριου της 5-αμινο-2,3-διυδροφθαλαζιν-1,4-διονης, οι οποιες περιεχουν φαρμακευτικα σκευασματα και διαδικασιες για την παρασκευη τους
Inventor: BREU JOSEF
IPC: A61K31/502
Filed: 2014-08-04
Abstract: Η εφεύρεση σχετίζεται με την παροχή δύο νέων Κρυσταλλικών μορφών και I και II για 5-αμινο-2, 3-διυδροφθαλαζίν-1, 4-Διώνη νατρίου. Παραδόξως ανακαλύφθηκε ότι η μορφή I και η μορφή II έχουν διαφορετικές επιπτώσεις στο ανοσοποιητικό σύστημα. Αυτή η πλεονεκτική ιδιότητα είναι χρήσιμη για ειδικές ανοσοποιητικές εφαρμογές. Επιπλέον, και οι δύο μορφές έχουν πλεονεκτικές φυσιοχημικές ιδιότητες οι οποίες είναι χρήσιμες στην παραγωγή, την περαιτέρω επεξεργασία και/ή χρήση φαρμακευτικών παρασκευασμάτων της μορφής I, της μορφής II ή μία μίξη των δύο.
Patent CY-1116966-T1 (CY)
Title: Νεα σκευασματα που σταθεροποιουν κι αναστελλουν την καταβυθιση ανοσογονων συνθεσεων
Inventor: KHANDKE LAKSHMI
IPC: A61K39/09
Filed: 2015-11-26
Abstract: Η παρούσα εφεύρεση ασχολείται με μια υπάρχουσα ανάγκη της τεχνικής για βελτίωση της σταθερότητας ανοσογόνων συνθέσεων όπως συζευγμάτων πολυσακχαρίτη-πρωτεϊνης και πρωτεϊνικών ανοσογόνων. Η εφεύρεση σχετίζεται γενικά με νέα σκευάσματα που σταθεροποιούν κι αναστέλλουν την καταβύθιση ανοσογόνων συνθέσεων. Ειδικότερα, η εφεύρεση που περιγράφεται στη συνέχεια ασχολείται με μια ανάγκη στην τεχνική για σκευάσματα που σταθεροποιούν κι αναστέλλουν το σχηματισμό σωματιδίων (π.χ. συσσωμάτωση, καταβύθιση) ανοσογόνων συνθέσεων που έχουν υποστεί επεξεργασία, ανάπτυξη, παρασκευή σκευάσματος, παρασκευή, και/ή αποθήκευση σε μέσα περιέκτη όπως δοχεία ζύμωσης, βιοαντιδραστήρες, φιαλίδια, φιάλες, σάκους, σύριγγες, ελαστικά πώματα, σωληνώσεις κλπ.
Patent CY-1118661-T1 (CY)
Title: Φαρμακευτικη συνθεση, φαρμακευτικη δοσολογικη μορφη, διαδικασια για την παρασκευη τους, μεθοδοι για αντιμετωπιση και χρησεις αυτων
Inventor: SCHNEIDER PETER
IPC: A61K45/06
Filed: 2017-02-24
Abstract: Η παρούσα εφεύρεση αφορά φαρμακευτικές συνθέσεις που περιέχουν συνδυασμούς σταθερής δόσης ενός φαρμάκου αναστολέα SGLT-2 και ενός συνεργού φαρμάκου, διαδικασίες για την παρασκευή αυτών και τη χρήση τους στην αντιμετώπιση ορισμένων παθήσεων.
Patent CY-1119849-T1 (CY)
Title: Προ-συντηξης rsv f αντιγονα
Inventor: SWANSON KURT
IPC: C07K14/135
Filed: 2017-11-17
Abstract: Η εφεύρεση αφορά σε προ-σύντηξης RSV F πρωτεΐνη και πολυπεπτίδια που περιέχουν μία ή περισσότερες μεταλλάξεις αμινοξέος που σταθεροποιούν τη προ-σύντηξης διαμόρφωση ή αποσταθεροποιούν τη μετά τη σύντηξη διαμόρφωση. Η εφεύρεση επίσης αφορά σε μεθόδους για διέγερση ανοσοαπόκρισης προς προ-σύντηξης RSV F.
Patent CY-1124763-T1 (CY)
Title: Μεθοδος για την θεραπευτικη αντιμετωπιση της πρωτοπαθους αϋπνιας
Inventor: ZISAPEL NAVA
IPC: A61K9/20
Filed: 2021-08-31
Abstract: Η εφεύρεση σχετίζεται με ένα φάρμακο, για την θεραπευτική αντιμετώπιση και βελτίωση της αναζωογονητικής ποιότητας του ύπνου, σε έναν ασθενή που πάσχει από πρωτοπαθή αϋπνία, το οποίο περιέχει τουλάχιστον μια ένωση επιλεγμένη από μελατονίνη, άλλα μελατονινεργικά μέσα, αγωνιστές μελατονίνης και ανταγωνιστές μελατονίνης, σε μια αποτελεσματική ποσότητα σε εύρος 0.0025 ως 50 mg, και προαιρετικά ένα ή περισσότερα άλλα θεραπευτικός δραστικά μέσα.
Patent HR-P20100408-T1 (HR)
Inventor: ALMARIO GARCIA ANTONIO
IPC: A61K31/437
Filed: 2010-07-23
Abstract: Spoj formule (I): naznačen time štoR1 je: fenilna skupina ili naftilna skupina, gdje te dvije skupine mogu izborno biti supstituirane s jednim ili više atoma ili skupina, koje se, međusobno neovisno, bira između sljedećih atoma ili skupina: halogena, (C1-C6)alkila, (C3-C7)cikloalkila, (C3-C7)cikloalkil(C1-C3)alkilena, halogen(C1-C6)alkila, (C1-C6)alkoksi, (C3-C7)cikloalkoksi, (C3-C7)cikloalkil(C1-C3)alkilenoksi, halogen(C1-C6)-alkoksi, (C1-C6) tioalkila, -S(O)(C1-C6)alkila, -S(O)2(C1-C6-alkila), hidroksila, cijano, nitro, hidroksi (C1-C6)alkilena, NRaRb(C1-C6)alkilena, (C1-C6)alkoksi (C1-C6)alkilenoksi, NRaRb, CONRaRb, SO2NRaRb, NRcCORd, OC(O)NRaRb, NRcC(O)ORe, NRcSO2Re, aril(C1-C6)alkilena, aril ili heteroarila, gdje je aril ili heteroaril izborno supstituiran s jednim ili više supstituenata, koje se bira između halogena, ili (C1-C6)alkilne, (C3-C7)cikloalkilne, (C3-C7)cikloalkil(C1-C3)alkilenske, halogen(C1-C6)alkilne, (C1-C6)alkoksi, halogen(C1-C6)alkoksi, NRaRb, hidroksilne, nitro ili cijano skupine; R2 i R3 su, međusobno neovisno, atom vodika, (C1-C6)alkilna, (C3-C7)cikloalkilna ili (C3-C7)cikloalkil(C1-C3)alkilenska skupina, gdje je ta skupina izborno supstituirana s Rf skupinom; arilna skupina, gdje je aril izborno supstituiran s jednim ili više supstituenata, koje se bira između halogena ili (C1-C6)alkilne, (C3-C7)cikloalkilne, (C3-C7)cikloalkil(C1-C3)alkilenske, halogen(C1-C6)alkilne, (C1-C6)alkoksi, halogen(C1-C6)alkoksi, NRaRb, hidroksilne, nitro ili cijano skupine; R4 je: atom vodika, (C1-C6)alkilna, (C3-C7)cikloalkilna ili (C3-C7)cikloalkil(C1-C3)alkilenska skupina, gdje je ta skupina izborno supstituirana s Rf skupinom; arilna skupina, gdje je aril izborno supstituiran s jednim ili više supstituenata, koje se bira između halogena ili (C1-C6)alkila, (C3-C7)cikloalkila, (C3-C7)cikloalkil(C1-C3)alkilena, halogen(C1-C6)alkila, (C1-C6)alkoksi, (C3-C7)cikloalkoksi, (C3-C7)cikloalkil(C1-C3)alkilenoksi, halogen(C1-C6)alkoksi, NRaRb, hidroksilne, nitro, cijano, (C1-C6)alkil(CO)-, CONRaRb, NRcCORd, OC(O)NRaRb, NRcC(O)ORe ili arilne skupine, gdje je aril izborno supstituiran s jednim ili više supstituenata, koje se bira između halogena ili (C1-C6)alkilne, (C3-C7)cikloalkilne, (C3-C7)cikloalkil(C1-C3)alkilenske, halogen(C1-C6)alkilne, (C1-C6)alkoksi, halogen(C1-C6)alkoksi, NRaRb, hidroksilne, nitro ili cijano skupine; Ra i Rb su, međusobno neovisno, atom vodika ili (C1-C6)alkil, (C3-C7)cikloalkil, (C3-C7)cikloalkil(C1-C3)alkilenska, aril(C1-C6)alkilenska ili arilna skupina; ili Ra i Rb tvore, zajedno s atomom dušika koji ih nosi, azetidinsku, pirolidinsku, piperidinsku, azepinsku, morfolinsku, tiomorfolinsku, piperazinsku ili homopiperazinsku skupina, gdje je ta skupina izborno supstituirana s (C1-C6)alkilnom, (C3-C7)cikloalkilnom, (C3-C7)cikloalkilnom (C1-C6)alkilenskom, arilnom ili aril(C1-C6)alkilenskom skupinom; Rc i Rd su, međusobno neovisno, atom vodika ili (C1-C6)alkilna, (C3-C7)cikloalkilna, (C3-C7)cikloalkil(C1-C3)alkilenska, aril(C1-C