baber/WOPTO huggingface dataset:
Patent DE-69533833-D1 (DE)
Inventor: KOJIRI KATSUHISA
IPC: A61K31/7056
Filed: 1995-05-02
Granted: 2005-01-05
Abstract: This invention relates to compounds of the general formula <CHEM> or pharmaceutically salts thereof, wherein R<1> and R<2> each represent an OH group, R<1> is located at the 1- or 2-position, R<2> is located at the 10- or 11-position, R<2> is located at the 11-position when R<1> is located at the 1-position, and R<2> is located at the 10-position when R<1> is located at the 2-position. The compounds of the present invention have an excellent antitumor effect and are hence useful as antitumor agents in the field of medicine.
Patent DE-69606531-D1 (DE)
Inventor: CLARK WILLIAM STEPHEN PATRICK
IPC: B32B5/26
Filed: 1996-05-20
Granted: 2000-03-09
Abstract: A reinforced fabric comprising one or more layers of fabric material backed by or sandwiching one or more yarn-based scrims wherein the or each scrim is a non-woven scrim is described. Non-woven scrims are stronger in the plane of the fabric and more simple to manufacture than woven scrims. Such fabrics are suitable for use as filtering felts. A process for preparing reinforced fabrics is also described. The scrim(s) for the process may be made on-line.
Patent DE-69613601-D1 (DE)
Inventor: DESOOMER JEAN-PAUL
IPC: A23L17/00
Filed: 1996-01-29
Granted: 2001-08-09
Abstract: Prepn. of deep frozen raw fish prod. which is free from gelling agent, starch, starchy matter, polyphosphate or material other than protein, salt or ingredients modifying the softness or taste and which comprises 90-75% of coarse pieces of fish (including connective tissue) coated by 10-25% of a fish paste consisting of ground and minced fish flesh, forming a binder and including the entire water content of the paste and pieces. The process pref. comprises: (i) partially defrosting blocks of frozen fish to between -10 and -2 (pref. between -5 and -2) degrees C; (ii) mincing 10-25% of the partly defrosted meat, opt. with addn. of a small amt. of salt and/or protein matter, to obtain a fine, sticky paste; (iii) mincing the rest of the partially defrosted meat coarsely to give coarse pieces; (iv) adding the pieces to the paste to form a uniform mixt.; and (v) moulding and deep-freezing the mixt. The coarse pieces measure 2-10 mm and are prepd. from fillets, whereas the paste is prepd. from minced fish meat. Coarse pieces and paste are made from white fish e.g. Alaskan hake, cod, French cod, opt. contg. a small amt. of salmon, trout, shellfish and/or crustacea.
Patent DE-69620314-D1 (DE)
Inventor: ACHTEREEKTE HENDRIKUS LEONARDU
IPC: A47G9/00
Filed: 1996-07-23
Granted: 2002-05-08
Abstract: The invention relates to a pillow (1) comprising a cover (2) containing filling material (3), wherein a firmness-providing element (5,7) is also arranged in the cover (2). This firmness-providing element (5,7) is preferably elongate in form and can for instance be manufactured from foam material. In order to prevent the firmness-providing element (5,7) from beginning to drift inside the cover, a number of variants are proposed in the application for fixing the element to the cover. <IMAGE>
Patent DE-69622912-D1 (DE)
Inventor: RUNKLE MARK ANDREW
IPC: H02K47/26
Filed: 1996-04-19
Granted: 2002-09-19
Abstract: A hydroelectric power generation system (20) generates electrical power for an electrical utilization system (72). A controller (42) obtains a requested output electrical power level from a hydro-turbine unit (70) by using a signal indicative of water head (hmeas) to control speed of an asynchrcnous rotary converter (50) coupled to the hydro-turbine unit and to control gate position of the hydro-turbine unit. The requested output electrical power level is applied from the hydro-turbine unit via the rotary converter to the electrical utilization system. In one embodiment, the controller (42B) accesses an updatable memory wherein Hydraulic Hill Chart intormation is stored. In another embodiment, the controller (42C) also includes a real-time automatic governor which uses a signal indicative of ac transmission frequency to the electrical utilization system to control the output electrical power level of the rotary converter. <IMAGE>
Patent DE-69623267-D1 (DE)
Inventor: RAUSCH W
IPC: C07K14/805
Filed: 1996-03-22
Granted: 2002-10-02
Abstract: A method for producing a stable polymerized hemoglobin blood-substitute from blood characterized in the use of a chromatographic column, is disclosed. The method of this invention includes mixing blood with an anticoagulant to form a blood solution, washing the red blood cells in the blood solution and then separating the washed red blood cells from the white blood cells. This method also includes disrupting the red blood cells to release hemoglobin and form a hemoglobin solution, which is then treated by high performance liquid chromatography to form a hemoglobin eluate. The hemoglobin eluate is then deoxygenated, contacted with a first reducing agent to form an oxidation-stabilized deoxygenated hemoglobin solution, and mixed with a cross-linking agent to form a polymerization reaction mixture, which is then polymerized. The polymerized hemoglobin solution is then diafiltered with a physiologic solution and with a reducing agent, whereby the polymerized hemoglobin solution is made physiologically acceptable, and whereby the reducing agent scavenges oxygen, to form a stable polymerized hemoglobin blood-substitute which is then packaged and stored in an atmosphere substantially free of oxygen. Compositions made by the methods are also disclosed, as are methods of therapeutically, or prophylactically, treating a vertebrate to increase tissue oxygenation, or prevent oxygen depletion, in tissue of the vertebrate.
Patent DE-69627532-D1 (DE)
Inventor: FERRARI K
IPC: A61K35/76
Filed: 1996-06-06
Granted: 2003-05-22
Abstract: A method for the production of adeno-associated virus stocks and recombinant adeno-associated virus stocks that are substantially free of contaminating helper virus is described. The method utilizes transfection with helper virus vectors to replace the infection with helper virus used in the conventional method.
Patent DE-69705524-D1 (DE)
Inventor: YAZAMI RACHID
IPC: C01B31/00
Filed: 1997-04-21
Granted: 2001-08-09
Abstract: The invention relates to new carbons containing fluorine. The carbons containing fluorine are obtained from a graphite or a mosaic textured graphitisable compound containing carbon. As a first step, the graphite or the carbon-containing compound is reacted with a gaseous mixture (HF+F2) in presence of an MFn fluoride at a temperature range between 15° C. and 80° C., M representing an element selected among I, Cl, Br, Re, W, Mo, Nb, Ta, B, Ti, P, As, Sb, S, Se, Te, Pt, Ir, and Os and n representing the valency of the element M, with n>=7. As a second step, the compound obtained at the end of the first step is reacted with fluorine for 1 to 20 hours at a temperature range between 20° C. and 400° C. The invention is useful as an active electrode material.
Patent DE-69706868-D1 (DE)
Inventor: CORTI MARCO
IPC: B41F35/00
Filed: 1997-11-14
Granted: 2001-10-25
Abstract: The branches of the channels for feeding the cleaning fluids, formed in the dispensing bar (1), continue to fork (B1, B2, B3, B4, B5, B6, B7, B8, B9, B10, B11, B12, B13, B14, B15), optionally finally splitting into three-way branches (T1, T2, T3, T4, T5, T6, T7, T8), until each dispensing hole (10) is fed by its own channel, so that the flow of fluids is distributed essentially in equal amounts and at the same pressure between the various dispensing holes (10) in the bar. The cleaning liquids are fed by respective reciprocating positive displacement pumps (63, 163) which are activated by pneumatic actuators (65, 165) having a piston which is suitably larger than the piston (64, 164) of the said pumps and being activated by the stream of air produced by the same source and at the same pressure as that conveyed to the dispensing bar, mixed together with the liquids dispensed by the pumps, in order to convey and atomize the said liquids. This ensures that the delivery pressure of the cleaning liquids is always correlated to and greater than the pressure of the stream of air, even when the latter is subject to variations in pressure. <IMAGE>   <IMAGE>
Patent DE-69709327-D1 (DE)
Inventor: NOWAKOWSKI Z
IPC: D21F5/00
Filed: 1997-02-19
Granted: 2002-01-31
Abstract: A Yankee hood comprises an integral air heating system combining the hood with circulating fans, air heaters and an air flow duct work distribution system into one assembly with the air system apparatus located inside the hood. Motors for circulating fans and the burner assemblies are mounted on the external face of the hood drive side.
Patent DE-69711893-D1 (DE)
Inventor: HOFMANN A
IPC: C12N15/87
Filed: 1997-01-27
Granted: 2002-05-16
Abstract: An electroporation method and apparatus generating and applying an electric field according to a user-specified pulsing scheme. Advantageously, one such pulse includes a low voltage pulse of a first duration, immediately followed by a high voltage of a second duration, immediately followed by a low voltage of a third duration. The low voltage electroporation field accumulates molecules at the surface of a cell, the appropriately high voltage field creates an opening in the cell, and the final low voltage field moves the molecule into the cell. The molecules may be DNA, portions of DNA, chemical agents, the receiving cells may be eggs, platelets, human cells, red blood cells, mammalian cells, plant protoplasts, plant pollen, liposomes, bacteria, fungi, yeast, sperm, or other suitable cells. The molecules are placed in close proximity to the cells, either in the interstitial space in tissue surrounding the cells or in a fluid medium containing the cells.
Patent DE-69728864-D1 (DE)
Inventor: PANDOLFO MASSIMO
IPC: C12Q1/68
Filed: 1997-03-04
Granted: 2004-06-03
Abstract: This invention relates generally to methods for the diagnosis and therapeutic treatment of Friedreich Ataxia. Friedreich ataxia (FRDA) is an autosomal recessive, degenerative disease that involves the central and peripheral nervous system and the heart. A gene, X25, was identified in the critical region for the FRDA locus on chromosome 9q13. The gene encodes a 210 amino acid protein, frataxin, that has homologues in distant species such as C. elegans and yeast. A few FRDA patients have been found to have point mutations in X25, but the vast majority are homozygous for a variable, unstable GAA trinucleotide expansion in the first X25 intron. Mature X25 mRNA was severely reduced in abundance in individuals with FRDA. Carriers and individuals at risk for developing FRDA can be ascertained by the methods of the present invention. Further, the methods of the present invention provide treatment to those individuals having FRDA.
Patent DE-69733204-D1 (DE)
Inventor: HIRATA YUICHI
IPC: C12N15/18
Filed: 1997-07-15
Granted: 2005-06-09
Abstract: A novel human gene having a significant homology with a VEGF-C gene, a member of the VEGF family, has been isolated by the PCR method using primers designed based on the sequence of EST that is assumed to be homologous with the C-termial region of the VEGF-C gene. Mouse and rat genes have been isolated based on the human gene isolated as above. A protein encoded by the above human gene has been isolated by introducing the gene into Escherichia coli and expressing it. The isolated protein and genes can be applied to, for example, gene therapy for the VEGF-D deficiency, wound healing, and promotion of collateral vessel formation. Furthermore, VEGF-D protein inhibitors can be used as a novel anticancer drug, etc.
Patent DE-69740029-D1 (DE)
Inventor: FOLEY KEVIN THOMAS
IPC: A61B17/00
Filed: 1997-03-14
Granted: 2010-12-02
Abstract: A method for accessing the spine includes making an incision in the skin of a patient. The skin and tissue can be dilated, and a cannula inserted through the dilated skin and tissue. The cannula includes a distal end positioned adjacent a first working space that includes paraspinous tissue. The cannula can be repositioned through the incision to a second working space adjacent the distal end of the cannula.
Patent DE-69828491-D1 (DE)
Inventor: ESKILDSEN CHRISTIAN
IPC: H05B6/12
Filed: 1998-03-13
Granted: 2005-02-10
Abstract: PCT No. PCT/DK98/00097 Sec. 371 Date Oct. 14, 1999 Sec. 102(e) Date Oct. 14, 1999 PCT Filed Mar. 13, 1998 PCT Pub. No. WO98/41062 PCT Pub. Date Sep. 17, 1998A core structure for induction heating apparatus consists of radially disposed core parts carrying cylindrical coils for energization. The core parts join the outer end to form a rim and at the center to form a central pole.
Patent DE-69829175-D1 (DE)
Inventor: EVERS MICHEL
IPC: C12P21/04
Filed: 1998-04-27
Granted: 2005-04-07
Abstract: Cyclosporin derivatives of formula (I) in which R is H or a radical (Ia) or (Ib) as defined herein; R' is a radical (Ic) or (Id) as defined herein; and R''represents H or OH, with the proviso that R and R'' are not simultaneously H, and pharmaceutically acceptable salts thereof, when they exist, are disclosed as useful for the treatment and/or prophylaxis of retrovirus infections.
Patent DE-69831411-D1 (DE)
Inventor: GROSS HERBERT
IPC: C08L71/02
Filed: 1998-06-19
Granted: 2005-10-06
Abstract: A composition comprising: (i) a homopolymer of ethylene made by a high pressure process, and, based on 100 parts by weight of component (i), (ii) about 2 to about 15 parts by weight of a copolymer of ethylene and an acrylic acid ester or methacrylic acid ester, said ester being present in the copolymer in an amount of about 10 to about 30 percent by weight based on the weight of the copolymer; and (iii) about 0.03 to about 0.3 part by weight of a polyethylene glycol having a molecular weight in the range of about 1000 to about 100,000.
Patent DE-69832302-D1 (DE)
Inventor: BALANDRIN F
IPC: A61P25/28
Filed: 1998-12-09
Granted: 2005-12-15
Abstract: Bis(Fluorophenyl)alkylamides have been chemically synthesized which possess beneficial pharmacological properties (e.g., anticonvulsant activity) useful for the treatment of neurological diseases or disorders, such as, for example, epilepsy, convulsions, and seizure disorders. The preferred compounds of the invention also cause little sedation and have high therapeutic and protective indices in animal models of epilepsy. These compounds further possess long pharmacologic half-lives, which, in practical clinical therapeutic application, should translate into once-a-day dosing, of great benefit to patients suffering from these diseases and/or disorders. These compounds may also be of further clinical utility in the treatment of other diseases and disorders of the central and peripheral nervous systems, or diseases or disorders affected by them, including, but not limited to, spasticity, skeletal muscle spasms and pain, restless leg syndrome, anxiety and stress, and bipolar disorder.
Patent DE-69832972-D1 (DE)
Inventor: MORELLI JOSEPH PAUL
IPC: C07D317/34
Filed: 1998-04-23
Granted: 2006-02-02
Abstract: The present invention relates to orthocarbonate pro-fragrances useful for delivery of sustained perfume or fragrance to fabric treated with a laundry detergent composition which comprises the herein described pro-fragrances. The orthocarbonate pro-fragrances are also suitable for use in hard surface cleaning compositions. The orthocarbonate pro-fragrances are further suitable for use in personal care compositions. The present invention also relates to method for delivering a pleasurable scent to fabric which has a lasting freshness quality by contacting the fabric with the fragrance-releasable orthocarbonate pro-fragrances of the present invention.
Patent DE-69834269-D1 (DE)
Inventor: BIEDERMANN ELFI
IPC: A61K31/44
Filed: 1998-12-16
Granted: 2006-05-24
Abstract: The invention relates to new piperidinyl-substituted pyridyl carboxamides of the general formula (I), wherein the structure element E has meanings (E1) or (E2) and whereby the heterocyclic ring can optionally have a double bond. These substances have especially high cytostatic activities and pronounced immunosuppressive properties which make them suitable for therapeutic treatment in broad tumor spectrum.
Patent DE-69839097-D1 (DE)
Inventor: JAEKAERAE JUKKA
IPC: D21C9/16
Filed: 1998-12-18
Granted: 2008-03-20
Abstract: The invention relates to a process for the bleaching of chemical pulp and the use of a bleaching solution. According to the invention the pulp is treated in a plurality of different steps by using at least in one step a bleaching solution which contains a peracid, and the essential idea of the invention is that the peracid is used in a post-bleaching which is the last step of the bleaching process, the post-bleaching being carried out in the presence of one or more earth-alkali metal compounds. By using a peracid the pulp is brought to its final brightness, and the purpose of the earth-alkali metal added is to combat the lowering of the viscosity of the pulp. According to the invention the post-bleaching can be carried out after the bleach plant steps in a pulp flow pipe, a storage tower or in the paper machine at a paper mill.
Patent DE-69900939-D1 (DE)
Inventor: GEMESIO DIEGO
IPC: B60R9/058
Filed: 1999-03-19
Granted: 2002-04-04
Abstract: A load-carrier device comprises a transverse bar (2) and a pair of supports (3) arranged towards the ends of the transverse bar (2). Each of the supports (3) is provided with a bearing foot (5) and with means for securing the support to the roof of the vehicle. Each of the securing means comprises an inextensible tensioning strip (20) to which a coupler (21) for engaging the edge of the vehicle roof is connected. The strip (20) is slidable on a bearing surface, the inclination of which can be varied or modified in such a manner that, irrespective of the shape of the edge region of the roof and for a whole range of distances between the support and the edge of the roof, the strip follows, between the support (3) and the coupler (21), a path in which the strip (20) is adjacent to the edge region of the roof, but does not come into contact therewith.
Patent DE-69907331-D1 (DE)
Inventor: NISHIGUCHI TSUTOMU
IPC: A01N43/90
Filed: 1999-07-23
Granted: 2003-06-05
Abstract: The present invention relates to a fungicidal composition obtained by mixing a 1,2,3-thiadiazole derivative of general formula (I) useful as a plant disease controller with at least one fungicide selected from the compounds having a fungicidal activity against plant diseases, and to a method for using the same: <CHEM> wherein R<1> is hydrogen, alkyl or cycloalkyl and R<2> is CO-Y-R<3>, wherein Y is O, S, NR<4> or the like and R<3> is hydrogen, alkyl, phenyl, 5- or 6-membered heterocycle or the like.
Patent DE-69910211-D1 (DE)
Inventor: JAHROMI SHAHAB
IPC: C08J7/048
Filed: 1999-04-15
Granted: 2003-09-11
Abstract: The invention relates to a composite material and a process for manufacturing the composite material by applying at least a single organic barrier  layer to a substrate. Depending on the intended application, the composite material may also include an outer cover layer over the barrier layer to improve moisture resistance. The preferred materials are triazines, particularly melamine, that are vapour-deposited onto the substrate to form a thin, durable, barrier layer. The layer may be transparent.
Patent DE-69912393-D1 (DE)
Inventor: ICHITANI NOBORU
IPC: B01J8/24
Filed: 1999-02-04
Granted: 2003-12-04
Abstract: A multi-chamber fluidized bed classifying apparatus is provided. In the apparatus, a main chamber having a fluidized bed 14 arranged on wind boxes 16, 17 through a perforated gas distributing plate 12 is divided into a drying chamber 13 and a classifying chamber 15 by a partition plate 11. A communication passage 19 is defined under the plate 11. The wind boxes 16, 17 have respective lower ends connected to "falls" discharge devices 29a, 29b, respectively. The wind box 16 is connected to a "processing" fluidization gas supply system for supplying the fluidization gas into the box 16, while the wind box 17 is connected to a "classifying" fluidization gas supply system for supplying the fluidization gas into the box 17. The "classifying" fluidization gas supply system is provided with a flow control unit which adjusts the quantity of gas supplied into the classifying chamber 15 to control the size of classified particles. The "processing" fluidization gas supply system is provided with a control unit; which adjusts the gas quantity and/or the temperature of gas supplied into the drying chamber 13. <IMAGE>
Patent DE-69934301-D1 (DE)
Inventor: AMAKAWA KOJI
IPC: G06F19/00
Filed: 1999-02-08
Granted: 2007-01-18
Abstract: A system is disclosed for determining a path in a network that decreases the number of disk accesses needed during the pathfinding computation. The network is divided in to a set of tiles. Certain sub-paths are pre-computed. The pre-computed sub-paths are grouped into webs. When finding a path, the system will perform a pathfinding exploration within the tile for the origin and a pathfinding exploration within the tile for the destination. A number of the webs will be used with the two explorations to determine a path from the origin to the destination.
Patent DE-69934327-D1 (DE)
Inventor: TERWILLIGER RICHARD
IPC: A61B10/00
Filed: 1999-07-13
Granted: 2007-01-18
Abstract: The present invention includes a biopsy needle for use in a biopsy gun or as surgical instrument, capable of taking multiple samples, and a guiding needle holder for holding a biopsy needle. The biopsy needle includes an inner needle, also called a stylet, and an outer needle, also called a cannula, and a guiding needle holder. The stylet has a recess in the vicinity of its distal end which receives the tissue sample. The guiding needle holder includes an integrated spacer, and first and second connecting elements. The first connecting element holds the proximal end of the cannula and is displaceably attached along the length of the integrated spacer. The second connecting element holds the proximal end of the stylet and is fixedly attached to the distal end of the integrated spacer. The connecting elements each have an opening that facilitates insertion of the biopsy needle into a known biopsy gun in either the cocked or uncocked position. In an alternate embodiment, the guiding needle holder includes an integrated spacer that fixedly holds the stylet, and a connecting element that displaceably holds the cannula.
Patent DE-69935449-D1 (DE)
Inventor: JETHMALANI JAGDISH M
IPC: A61F2/16
Filed: 1999-10-13
Granted: 2007-04-19
Abstract: The present invention relates to lenses that are capable of post-fabrication power modifications. In general, the inventive lenses comprise (i) a first polymer matrix and (ii) a refraction modulating composition that is capable of stimulus-induced polymerization dispersed therein. When at least a portion of the lens is exposed to an appropriate stimulus, the refraction modulating composition forms a second polymer matrix. The amount and location of the second polymer matrix may modify a lens characteristic such as lens power by changing its refractive index and/or by altering its shape. The inventive lenses have a number of applications in the electronics and medical fields as data storage means and as medical lenses, particularly intraocular lenses, respectively.
Patent DE-69936538-D1 (DE)
Inventor: FARROW STUART NEVILLE
IPC: C07K16/28
Filed: 1999-10-05
Granted: 2007-08-23
Abstract: The invention provides an isolated protein which is a member of the TNF ligand superfamily and comprising i) a polypeptide having the amino acid sequence of figure 1 or ii) a variant of the polypeptide of i).