Patent SG-11201809474T-A (SG)
Title: Compositions and methods for bioengineered tissues
Inventor: HANSON ARIEL DAWN
IPC: C12N7/00
Filed: 2017-05-05
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization MUNIIIIIMUMINHOHMEHIMMEMIN International Bureau (10) International Publication Number (43) International Publication Date ....0\". WO 2017/196668 Al 16 November 2017 (16.11.2017) WIPO I PCT (51) International Patent Classification: more Road, Chapel Hill, North Carolina 27514 (US). C12N 5/00 (2006.01) C12N 5/071 (2010.01) DINH, Timothy Anh-Hieu; 210 Ridge Trail, Chapel Hill, A61L 27/24 (2006.01) C12N 5/09 (2010.01) North Carolina 27516 (US). SETHUPATHY, Praveen; A61L 27/36 (2006.01) C12N 7/00 (2006.01) 512 Rollesby Court, Hillsborough, North Carolina 27278 (21) International Application Number: (US). REID, Lola M.; 3621 Sweeten Creek Road, Chapel PCT/US2017/031320 Hill, North Carolina 27514 (US). (22) International Filing Date: (74) Agent: VILLACORTA, Gilberto M. et al.; FOLEY & LARDNER LLP, 3000 K Street N.W., Suite 600, Washing- 05 May 2017 (05.05.2017) ton, District of Columbia 20007-5109 (US). (25) Filing Language: English (81) Designated States (unless otherwise indicated, for every (26) Publication Language: English kind of national protection available): AE, AG, AL, AM, (30) Priority Data: AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, 62/335,013 11 May 2016 (11.05.2016) US CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, 15/586,061 03 May 2017 (03.05.2017) US DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, (71) Applicant: THE UNIVERSITY OF NORTH CAROLI- KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, NA AT CHAPEL HILL [US/US]; Office of Commer- MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, cialization and Economic Development, 100 Europa Drive, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, Suite 430, Chapel Hill, North Carolina 27517 (US). SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, — TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. — (72) Inventors: HANSON, Ariel Dawn; 55 Hall Ave., Apt. = 3, Sommerville, Massachusetts 02144 (US). YAMAUCHI, (84) Designated States (unless otherwise indicated, for every Mitsuo; 208 Silver Creek Trail, Chapel Hill, North Car- kind of regional protection available): ARIPO (BW, GH, olina 27514 (US). WAUTHIER, Eliane Lucie; 720 Ken- GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, = = (54) Title: COMPOSITIONS EE EE EE 2000- 1800- - 1600- 1400- = 1200- 1000- = 800- _ g 600- = = 1 4 AND , t METHODS FOR BIOENGINEERED TISSUES , i lt 1 1 IlfAii IMFRESH 0.,,,,..P_., 4 ,. FIG IA TISSUE IE titiltifattttikttil BIOiAATRIX SCAFFOLD = GROWTH FACTORS = = — ,-1 'i FIG. 18 FIE IC GC ,tD ,D ,tD t:T ,-1 IN N (57) : The present disclosure positions employed in generation ' FIG. ID provides methods for producing bioengineered thereof. FIG. IE tissue along apparatus and other relevant com- [Continued on next page] WO 2017/196668 Al MIDEDIM1111011111111111111111111111111111111111111111111111011110111110111111111111 UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3))