baber/WOPTO huggingface dataset:
Patent BG-65988-B1 (BG)
Title: Polymorphisms in the human mdr - 1 gene and their use in diagnostic and therapeutic applications
Inventor: BRINKMANN ULRICH
IPC: C12Q1/68
Filed: 2002-01-29
Abstract: Described are general means and methods of diagnosing and treating the phenotypic spectrum as well as the overlapping clinical characteristics with several forms of inherited abnormal expression and/or function of the Multi Drug Resistance-1 (MDR-1) gene. In particular, polynucleotides of molecular variant MDR-1 genes which, for example, are associated with unsufficient and/or altered uptake of drugs by a target cell, and vectors comprising such polynucleotides are provided. Furthermore, host cells comprising such polynucleotides or vectors and their use for the production of variant MDR-1 proteins are described. In addition, variant MDR-1 proteins and antibodies specifically recognizing such proteins as well as concerns transgenic non-human animals comprising the above-described polynucleotide or vectors are provided. Described are also methods for identifying and obtaining inhibitors for therapy of disorders related to the malfunction of the MDR-1 gene as well as methods of diagnosing the status of such disorders. Pharmaceutical and diagnostic compositions comprising the above-described polynucleotides, vectors, proteins, antibodies and inhibitors by the above-described method are provided. Said compositions are particularly useful for diagnosing and treating various diseases with drugs that are substrates, inhibitors or modulators of the MDR-1 gene product.
Patent BG-65084-B1 (BG)
Title: New class of bioactive glycoproteins
Inventor: YAMSKOVA VIKTORIYA
IPC: A61K35/413
Filed: 2002-03-13
Abstract: The invention relates to a bioactive chemical composition, more specifically to proteins and can be used in medicine, veterinary and cell biology. The inventive glycoproteins are extracted from an intercellular space of the tissue of various organs, blood serum and bile of vertebrates (human beings and animals). Said glycoproteins have a high biological activity in super low doses at a concentration ranging from 10-12 to 10-29 mol/liter and lower. It is thus possible to produce a pharmaceutical form including glycoprotein in an effective quantity and a pharmaceutically acceptable carrier. The glycoprotein protein produced finds application as a medicamentous form.
Patent BG-67406-B1 (BG)
Title: Ttwelve-rotor drone for remote sensing
Inventor: ZABUNOV SVETOSLAV
IPC: B64C27/08
Filed: 2019-08-23
Abstract: The invention relates to a twelve-rotor drone for remote sensing, the rotors of which are positioned below the plane of the frame. Due to the relative position of the rotors, their position relative to the plane of the glider and the configuration of the frame and the directions of rotation guarantee, minimum dimensions and mass, minimum power needed to generate the required aerodynamic force, maximum flight time, maximum mass of payload, and so forth. By means of the aerodynamic force created by the rotors, the flight of the drone and its movement in the airspace in vertical and horizontal directions is achieved. The airflow created by the rotors does not meet the planer that is above the rotors and does not create the undesireble downward resistance. On the other hand, the optimal configuration of the rotors relative to each other and the planer (frame) relative to the rotors guarantee a minimum mass of the aircraft. The direction of rotation of the rotors determines the minimum energy consumption for orienting the planer in space and for controlling the flight direction. Thus the flight time, flight range and payload are maximized. The application is in unmanned aircraft powered by electric motors and used for photographing and mapping and other activities in the fields of remote sensing as well as for military applications.
Patent CH-718818-B1 (CH)
Title: Procédé de fabrication d'un composant horloger en silicium
Inventor: Rémy Fournier
IPC: G04B13/02
Filed: 2021-05-05
Abstract: Le procédé de fabrication d'un composant horloger en silicium selon l'invention comprend les étapes suivantes : a) se munir d'une plaquette comprenant une première couche de silicium (2), une deuxième couche de silicium et, entre les deux, une couche intermédiaire d'oxyde de silicium ; b) graver la première couche de silicium (2) pour y former le composant horloger (5), au moins un élément de liaison (7) situé dans un évidement (6) du composant horloger (5) et au moins une attache (8) reliant cet élément de liaison (7) à une surface intérieure (6a) du composant horloger (5); c) éliminer la couche intermédiaire d'oxyde de silicium entre le composant horloger (5) et la deuxième couche de silicium et la laisser au moins partiellement entre l'élément de liaison (7) et la deuxième couche de silicium ; d) appliquer au moins un traitement au composant horloger (5) ; e) détacher le composant horloger (5) de la plaquette par rupture ou élimination de l'attache (8).
Patent CH-699694-B1 (CH)
Title: Sostanza colorante reattiva con gruppo ponte dialchiletere.
Inventor: CHEN CHIEN-YU
IPC: C09B62/01
Filed: 2009-09-01
Abstract: La presente invenzione si riferisce ad una sostanza colorante reattiva con gruppo ponte dialchiletere, rappresentata dalla formula seguente (I): in cui B, B´, E 1 , E 2 , Z, Z´, i, j, (R 1 ) 0 -3 , (R 2 ) 0 -3 , m ed n sono definiti così come nella descrizione brevettuale. La sostanza colorante reattiva della presente invenzione è adatta per tintura ad esaurimento, tintura in pezza a freddo, tintura in continuo, stampa e stampa a spruzzo digitale di materiali che contengono fibre di gruppo idrossile o di gruppo ammino.
Patent CH-710154-B1 (CH)
Title: Sitzeinrichtung.
Inventor: YILMAZ BODUK
IPC: A61B5/117
Filed: 2014-09-26
Abstract: Die Erfindung betrifft eine Sitzeinrichtung, insbesondere einen Bürosessel, mit einem Sitzelement, einer Rückenlehne, einem Trägergestell, an welchem das Sitzelement und die Rückenlehne bevorzugt mit einer Vielzahl von Gelenken angeordnet sind und an der Sitzeinrichtung angeordnete Sensoren. Die Sensoren erfassen von der Sitzeinrichtung erzeugte physikalische und/oder chemische Eigenschaften. Die Erfindung betrifft auch einen Nachrüstsatz für eine Sitzeinrichtung.
Patent CH-698425-B1 (CH)
Title: Anordnung zum Messen einer physikalischen Grösse.
Inventor: KAMM LARS
IPC: G01D3/036
Filed: 2006-12-01
Abstract: Die Erfindung betrifft eine Anordnung zum Messen einer physikalischen Grösse mit mehreren Messsensoren, bei der jedem Messsensor ein invertierender Messsignalverstärker (17.1, 17.2) nachgeschaltet ist, wobei je ein Ausgang eines Messsensors mit einem invertierenden Eingang des dem Messsensor nachgeschalteten invertierenden Messsignalverstärkers (17.1, 17.2) verbunden ist.
Patent EP-1034912-B1 (EP)
Inventor: SETA KUNIHITO
IPC: B29C45/77
Filed: 2000-03-07
Granted: 2002-11-27
Abstract: An injection molding machine includes a plasticating unit (B) for plasticating a thermoplastic resin, and an injecting unit (A) connected to the plasticating unit (B) through a connecting passage (3) to inject the plasticated resin into a mold (24). The injecting unit (A) includes a rotary pump (4) having a suction port (4a) connected to the plasticating unit through the connecting passage (3) and a discharge port (4b) connected to the mold (24). The plasticated resin is intermittently injected into the cavity of the mold (24) through the injection port by means of the rotary pump (4). In the connecting passage (3), an accumulator (C) is provided which reserves the resin plasticated in the plasticating unit (B) in an amount equal to or more than the shot capacity, and feeds the resin to the rotary pump (4). A pressure sensor (25) or a torque limiter (15) is being applied for detecting the moment when feeding by the rotary pump (4) should be stopped. <IMAGE>
Patent EP-1101613-B1 (EP)
Inventor: IIJIMA TAKASHI
IPC: B41F31/02
Filed: 2000-04-25
Granted: 2005-08-24
Abstract: It was difficult to precisely adjust the distance between an outer circumferential surface of a fountain roller F and an ink supplying surface of an ink rail 1. Therefore, an ink rail for a printing press has an ink rail body 4, a pedestal 3, a supporting member 2 and a distance adjusting means 7. The ink rail body 4 has a concave curved surface formed over two members 5, 6 joined on a joining face so as to be divided, and also has an ink supplying surface 40 having plural ink supplying ports 56 opened to the concave curved surface along the joining face. The pedestal 3 supports the ink rail body 4 in a supporting plane parallel to the joining face of the ink rail body 4. The supporting member 2 supports the pedestal 3 so as to be angularly displaced. The distance adjusting means 7 can reciprocate the ink rail body 4 along the supporting plane of the pedestal 3 in a direction perpendicular to a longitudinal direction of the ink rail body 4. The joining face of the ink rail body 4 approximately conforms to a plane including a rotation central line of the fountain roller F in an operating position Y, and the concave curved surface of the ink rail body 4 can be approached and separated from the outer circumferential surface of the fountain roller F so as to adjust the distance therebetween. <IMAGE>
Patent EP-1061268-B1 (EP)
Inventor: BUETER JOSEF
IPC: F15B15/22
Filed: 2000-05-09
Granted: 2005-06-15
Abstract: The cylinder (1) consists of a cylinder tube (3) and a damping tube (4) connected to the cylinder tube. The damping tube has a flow off notch (23) which extends along the entire length of the cylinder. The central axis (24) of the notch is inclined with respect to the central axis of the cylinder at a tangent of 0.02 to 0.3.
Patent EP-1095591-B1 (EP)
Inventor: JABBUSCH WOLFGANG DR
IPC: A46B15/00
Filed: 2000-10-21
Granted: 2003-09-10
Abstract: The oral hygiene device to clean between the teeth, has a disposable cleaning membrane (5) fitted to a holder, of a very thin and elastic material in a rectangular shape. One longitudinal edge is secured to a base (6) to be mounted at the handle. Its lateral edges are shaped into supports (9) at right angles to the base (6) and with a transit into the base section. The cleaning membrane (5) is of an elastic plastics material, and the shaped side supports (9) have a stiff elasticity. The surface of the cleaning membrane (5) is roughened and can be coated with a cleaning agent.
Patent EP-1108570-B1 (EP)
Inventor: HOERMANSDORFER OTMAR
IPC: B62D61/12
Filed: 2000-11-22
Granted: 2007-09-19
Abstract: The vehicle has an air sprung driven rear axle (1) with an associated air sprung leading or trailing axle (2) and an air spring circuit (3.4) with an air spring bellows (3/1,3/2,4/1,4/2,5/1,6/1) per axle dimensioned according to the corresponding technically permitted axle load. The vehicle has a device for automatically changing between legally and technically permissible axle load ratios.
Patent EP-1129907-B1 (EP)
Inventor: OCHS LOTHAR
IPC: B60R1/074
Filed: 2000-12-22
Granted: 2004-08-18
Abstract: The mirror head (4) with glass is movable relative to the mirror foot (3) fixed on the vehicle body and includes detent cams and recesses between the head and foot parts to prevent damage to the drive. A stopper (30) is provided on the mirror head and a counter stopper (31) on the mirror foot. In the driving position the stopper can stop against the counter stopper when the detent means are disengaged but when the detent means are engaged the stopper cannot stop in a swivel position between the driving position and parking position.
Patent EP-1111777-B1 (EP)
Inventor: RIISHOEJ JESPER
IPC: H03H7/42
Filed: 2000-12-19
Granted: 2007-07-25
Abstract: A circuit interfacing balanced RF Power Amplifier (1) with unbalanced load (15) has first shunt inductor (5) and series capacitor (6) connected to first output (2) and first shunt capacitor (17) and series inductor (7) connected to second output (3) of amplifier, and comprises second shunt inductor (9) connected to second output and feeding current to this output. First shunt capacitor may correspond to sum of capacitors required to resonate with series inductor and second shunt inductor. Second shunt inductor may exceed value to resonate with capacitance of first shunt capacitor less capacitor required to resonate with series inductor, by same amount as first shunt inductor exceeds value to resonate with series capacitor. Circuit may further comprise second shunt capacitor (27) connected to first output, whereby first shunt capacitor exceeds sum of capacitors required to resonate with series inductor and second shunt inductor. <IMAGE>
Patent EP-1153001-B1 (EP)
Inventor: CHAUFFRIAT HENRI
IPC: C09D5/16
Filed: 2000-01-25
Granted: 2003-01-02
Abstract: The invention concerns a method for treating substrates comprising the following steps which consist in: 1) treating the substrates with a dispersion of photocatalytic particles; 2) treating the substrate with at least a siliconized compound selected among the siliconates and the polyorganosiloxanes.
Patent EP-1072166-B1 (EP)
Inventor: BAKER MATTHEW P J
IPC: H04Q11/04
Filed: 2000-01-24
Granted: 2005-12-21
Abstract: In order to enable isochronous data to be transmitted over communications systems which may introduce timing jitter each packet of isochronous data is provided with a timestamp which indicates to a receiver the time at which a packet should be processed. The receiver notes the time the first packet of a data stream arrive and adds a given offset time which is greater than or equal to the maximum jitter to produce a time t1. Each succeeding packet is processed at a time t=t1+(Tn-T1), where T1 is the timestamp in the first data packet and Tn is the timestamp in the current packet. Thus the processing at the receiver is dependent on the relative times of arrival of the packets rather than the absolute times defined by the timestamps.
Patent EP-1227784-B1 (EP)
Inventor: SAKAI YUKITOSHI
IPC: A61Q5/00
Filed: 2000-03-22
Granted: 2007-07-04
Abstract: Disclosed is hair conditioning compositions comprising antidandruff agent wherein the hair conditioning composition is substantially free of the group selected from a chelating agent, methylchloroisothiazolinone, and methylisothiazolinone. The compositions comprise by weight: (a) from about 0.1% to about 15% of a high melting point fatty compound; (b) compounds selected of; (b1a) from about 0.1% to about 10% of an amidoamine having the following general formula: R<SUP>1</SUP>CONH(CH<SUB>2</SUB>)<SUB>m</SUB>N(R<SUP>2</SUP>)<SUB>2 </SUB>wherein R<SUP>1 </SUP>is a residue of C<SUB>11 </SUB>to C<SUB>24 </SUB>fatty acids, R<SUP>2 </SUP>is a C<SUB>1 </SUB>to C<SUB>4 </SUB>alkyl, and m is an integer from 1 to 4 ; (b1b) an acid selected from the group consisting of 1 glutamic acid, lactic acid, hydrochloric acid, malic acid, acetic acid, fumaric acid, 1 glutamic acid hydrochloride, tartaric acid, and mixtures thereof, at a level such that the mole ratio of amidoamine to acid is from about 1:0.3 to about 1:1; or (b2) the combination of; (b2a) from about 0.1% to about 10% of a cationic conditioning agent; and (b2b) from about 0.1% to about 10% of a low melting point oil having a melting point of less than 25° C.; (c) a safe and effective amount of an antidandruff agent; (e) a preservative system comprising, by weight of the entire composition, from about 0.1% to about 1.0% of benzyl alcohol, from about 0.1% to about 1.0% of phenoxy ethanol, from about 0.05% to about 1.0% of methyl paraben, and from about 0.05% to about 1.0% of mettryl paraben, and from about 0.01% to about 1.0% of propyl paraben; and (f) an aqueous carrier.
Patent EP-1218548-B1 (EP)
Inventor: OBERSTE STEVEN
IPC: C12Q1/68
Filed: 2000-03-24
Granted: 2005-05-11
Abstract: The present invention discloses a method for detecting the presence of an enterovirus in a clinical sample. The invention additionally discloses a method for typing an enterovirus in a clinical sample. Both methods employ a set of primer oligonucleotides for reverse transcription and amplification that hybridize to conserved regions of the enterovirus genome, and that provide amplicons that include significant portions of the VP1 region that are characteristic of the various serotypes. In the typing method, the invention further provides a database consisting of nucleotide sequences from prototypical enteroviral serotypes, which is used to type the clinical sample by comparing the sequence of its amplicon with each prototypical sequence in the database. The invention additionally provides mixtures of primer oligonucleotides, and a kit for use in conducting the typing method that includes a mixture of the primer oligonucleotides.
Patent EP-1180231-B1 (EP)
Inventor: PHILIPP RUDI
IPC: F26B21/02
Filed: 2000-03-10
Granted: 2004-06-16
Abstract: In known rack dryers, the drying effect is weaker in the outer area on the side of the air intake into the pipe chambers than in the other areas. Said weaker drying effect is caused by turbulence in this area, which leads to a drop in the static pressure. The aim of the invention is to provide a dryer which ensures even drying of the goods across the entire width, even in the problem areas. The rack dryer is equipped with conductive bodies (20, 26) which are located on the partition wall (5) and which streamline the current in the area of the air intake into the pipe chambers in such a way, that a predominantly even static pressure prevails throughout the entire pipe chamber. The invention can be used for drying sandwich-type plaster board or wood veneer.
Patent EP-1185934-B1 (EP)
Inventor: HITE THOMAS D
IPC: H04L29/08
Filed: 2000-05-01
Granted: 2007-07-25
Abstract: A controller, method and computer medium are provided for controlling communications between a control area network and a data network. The method includes receiving user input at a controller coupled to the control area network from a node coupled to the data network, receiving user input at the controller from a node coupled to the control area network, and instructing an internet appliance coupled to the control area network to perform a command based on at least one of the received user inputs.
Patent EP-1285282-B1 (EP)
Inventor: MECKLER PETER
IPC: G01R31/12
Filed: 2000-05-20
Granted: 2005-04-27
Abstract: The invention relates to a method for detecting accidental arcs (arc tracking) on a cable (1), especially on a cable of an aircraft electrical system. According to said method, an alternating current signal (I(t)) that has been detected is sampled time-discretely and a trigonometric function (I(k)) imitating the alternating current characteristic is determined by interpolation of a number of sampling values (y(k)). The current alternating frequency (omega) is then derived from this trigonometric function. The result of a comparison of the current alternating current frequency (omega) and a set or reference frequency (omega') is used to determine the presence of an accidental arc (ISA,IGA) and a warning signal (Sarc) is optionally generated. A device which functions according to this method is advantageously integrated into a circuit-breaker (7) for the aircraft electrical system, so that the latter is equipped to detect and deactivate accidental arcs that occur on the electrical system cable (1).
Patent EP-1183223-B1 (EP)
Inventor: MANZER LEO E
IPC: C25B3/28
Filed: 2000-06-02
Granted: 2005-04-27
Abstract: L'invention concerne un procédé permettant de produire des perfluorooléfines représentées par la formule CF(R1f)=CF2, R1f représentant F ou CF3. Ce procédé implique a) la perfluoration des cyclobutanes représentés par la formule (I) (dans laquelle R2f représente F ou CF3, un R1 représente H et l'autre R1 représente H lorsque R2f représente F et représente CH3 lorsque R1f représente CF3), au moyen d'un procédé de fluoration électrochimique de Simons, dans une cellule électrochimique, dans une solution de fluorure d'hydrogène liquide anhydre, dans des conditions de température et de pression suffisantes pour remplacer tous les atomes d'hydrogène du cyclobutane représentés par la formule ci-dessus par de la fluorine; et (b) le craquage du cyclobutane perfluoré. Ledit craquage consiste à mettre les cyclobutanes perfluorés en contact avec du carbone ou un matériau conducteur chauffé par chauffage à induction à une température suffisante pour craquer les cyclobutanes perfluorés.
Patent EP-1181433-B1 (EP)
Inventor: LIMBECK ACHIM
IPC: F24J3/08
Filed: 2000-05-29
Granted: 2005-11-23
Abstract: The inventive drill has its own drive mechanism. As a result, said drill can be driven in using the water column to which it is subjected. This provides a very economical means of extracting hot water whereby water is guided under the earth surface through a sealed bore and then guided back up in a thermally insulated ascending pipeline.
Patent EP-1210137-B1 (EP)
Inventor: VOJTASEK WILLIAM
IPC: A61M5/32
Filed: 2000-08-02
Granted: 2011-06-15
Abstract: A device for inhibiting unintentional contact with the tip of a needle that has a wire guide disposed in a lumen thereof. A housing of the device has an interior cavity. A portion of the needle extends through the cavity and a tip of the needle is located outside of the housing during use of the needle. A pivoting member is located within the cavity and defines a distal opening and a proximal opening which are sized to allow the needle to pass through the openings. When the needle tip is within the cavity and the needle is withdrawn from the distal opening of the pivoting member, a spring or a compressible member cants the pivoting member into locking engagement with the needle to prevent further movement of the needle. Alternatively, a spring is in locking engagement with the needle to prevent its further movement. When the pivoting member is canted about the needle, a slot of the pivoting member is generally aligned with the tip of the needle so that the wire guide can extend through the slot while further forward movement of the needle through the slot is prevented.
Patent EP-1165937-B1 (EP)
Title: Sealing arrangement
Inventor: KASSEL DIETER
IPC: F16J15/06
Filed: 2000-09-05
Granted: 2005-12-14
Abstract: A sealing arrangement which comprises at least two abutting components that form a gap therebetween and a seal that sealingly bridges the gap. The inventive sealing arrangement is characterized in that the seal entirely consists of a matrix or is provided with a matrix representing a composite system. The matrix is combined with a base body and is a pasty mixture comprising a water-soluble material. A lubricant and a swelling agent which can be activated by means of water as well as optionally additional additives are mixed into the material. In an advantageous embodiment, the matrix is introduced into the chamber. The wall of the chamber is configured in the form of a web that can be torn out. The web is removed before assembly. The base body consisting of an elastomeric material is provided with channels and grooves which extend in an extruded-like manner.
Patent EP-1223798-B1 (EP)
Inventor: TISSIER ALAIN
IPC: A01H1/06
Filed: 2000-10-27
Granted: 2004-09-08
Abstract: The invention concerns a method for producing a bank or collection of mutants enabling the study of the function of each gene, DNA fragment or specific sequence of a given plant species and its applications: banks of mutants and selection of a gene mutant.