Patent SG-11201903247V-A (SG)
Title: Microfluidic device, microfluidic system and method for the isolation of particles
Inventor: MEDORO GIANNI
IPC: B01L3/00
Filed: 2017-10-18
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property MD HIM 0 11101 HOE 3E1 0 0111011111 MR HIDE 1111 011 Organization International Bureau (10) International Publication Number (43) International Publication Date .....0\"\"\"1 WO 2018/073767 Al 26 April 2018 (26.04.2018) WIP0 I PCT (51) International Patent Classification: CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, BOIL 3/00 (2006.01) DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, (21) International Application Number: HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, PCT/IB2017/056481 KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, (22) International Filing Date: OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, 18 October 2017 (18.10.2017) SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, (25) Filing Language: Italian TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (26) Publication Language: English (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, (30) Priority Data: GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, 102016000104612 18 October 2016 (18.10.2016) IT UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, 102016000104645 18 October 2016 (18.10.2016) IT TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, (71) Applicant: MENARINI SILICON BIOSYSTEMS MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, S.P.A. [IT/IT]; Via Giuseppe Di Vittorio, 21 B/3, 40013 TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, Castel Maggiore (IT). KM, ML, MR, NE, SN, TD, TG). (72) Inventors: MEDORO, Gianni; Via della Badia, 9, 40033 Casalecchio Di Reno (IT). CALANCA, Alex; Via Statale Published: _ Nord, 134, 41037 Mirandola (IT). MANARESI, Nicoll); — with international search report (Art. 21(3)) Via Santo Stefano, 132, 40125 Bologna (IT). = (74) Agent: MANGINI, Simone et al.; Studio Torta S.p.A., Via = Viotti, 9, 10121 Torino (IT). (81) Designated States (unless otherwise indicated, for every _ kind of national protection available): AE, AG, AL, AM, = = AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, (54) Title: MICROFLUIDIC DEVICE, = — — = = = — \" = 4 0 MICROFLUIDIC SYSTEM AND METHOD FOR THE ISOLATION OF PARTICLES (57) : A microfluidic device (2) for the isolation of particles of at /1 least one specific type of a sample (C1) is described. The microfluidic device 7 (2) comprises: a first inlet (4) adapted to receive a sample (C1) comprising the particles of the specific type, at least part of a separation group comprising 39 a separation unit (5), which comprises a main chamber (6) and a recovery chamber (7) and being adapted to receive the sample (C1) and to transfer at least part of the particles of the specific type from the main chamber (6) to the recovery chamber (7) in a selective manner with respect to further particles =a, = z of the sample (C1), a first outlet (8) which is designed to allow the particles of the specific type to be collected outside of the device and a second outlet = = - -7a ... r-- (10) adapted to allow at least a portion (C3) of the sample to flow out of the main chamber (6) and out of the microfluidic device (2). IN 19 IN Cr) N --.... 3 0 11 0 ei F I G . 1 I F ----- - C3 --C ,r36 ' 37 C