baber/WOPTO huggingface dataset:
Patent RU-2679596-C2 (RU)
Title: Nuclear reactor design
Inventor: ENGREMO Zhan-Zhak
IPC: G21C13/032
Filed: 2015-06-23
Granted: 2019-02-12
Abstract: FIELD: physics.SUBSTANCE: invention relates to the design of a nuclear reactor. Design of a nuclear reactor includes a reactor tank, at least one cylindrical steam generator comprising a tubular heat exchanger, the ends of which are connected to the inlet and outlet compartments of the means forming the water chamber, connected to the tank by means of forming a line containing the first channel for transporting the heated fluid from the tank to the steam generator through the inlet compartment of the means forming the water chamber. Design also comprises a second passage for transporting the cooled fluid from the steam generator to the tank through the outlet compartment of the means forming the water chamber. Means forming the line contain a single pipeline, the internal volume of which is divided to form the first and second channels.EFFECT: technical result is to minimize the size of the structure, facilitate the natural convection of the fluid and ensure the use of devices to prevent displacement between the reactor tank and the steam generator, in order to eliminate the possibility of the above-mentioned large gaps.14 cl, 4 dwg
Patent RU-2723018-C2 (RU)
Title: Способы лечения пациентов с высоким риском возникновения сердечно-сосудистых заболеваний, имеющих гиперхолестеринемию
Inventor: HANOTIN CORINNE
IPC: A61K39/00
Filed: 2015-07-16
Granted: 2020-06-08
Abstract: Изобретение относится к лечению гиперхолестеринемии. Раскрыто применение антитела или его антигенсвязывающего фрагмента, которые специфически связывают пропротеиновую конвертазу субтилизин/кексинового типа 9 (PCSK9) человека, содержащих три CDR тяжелой цепи: SEQ ID NO: 2, 3 и 4, и три CDR легкой цепи: SEQ ID NO: 7, 8 и 10, для лечения пациента, который имеет гиперхолестеринемию и уровень холестерина липопротеинов низкой плотности (LDL-C) выше 70 мг/дл, несмотря на лечение при помощи максимально переносимой терапии статинами; и установленное коронарное заболевание сердца (CHD) или эквивалентные риски возникновения CHD, где одна или несколько начальных доз в 75 мг антитела или его антигенсвязывающего фрагмента вводятся пациенту и где одна или несколько дополнительных доз в 75 мг антитела или его антигенсвязывающего фрагмента вводятся пациенту приблизительно через каждые две недели, если уровень LDL-C ниже 70 мг/дл; или одна или несколько дополнительных доз в 150 мг антитела или его антигенсвязывающего фрагмента вводятся пациенту через каждые две недели, если уровень LDL-C превышает или равен 70 мг/дл. Изобретение обеспечивает лечение гиперхолестеринемии, которая резистентна к терапии статинами. 11 з.п. ф-лы, 15 ил., 50 табл., 3 пр.
Patent RU-2709211-C2 (RU)
Inventor: SOUTHBY MARK CLIFT
IPC: C10M141/06
Filed: 2015-09-21
Granted: 2019-12-17
Abstract: Настоящее изобретение относится к применению беззольного модификатора трения, содержащего С 12 -С 24  жирную кислоту и С 12 -С 24  жирный амин, в моторном масле, содержащем базовое масло, для использования в картере двигателя для получения пониженного износа, а также для получения пониженного износа в присутствии нагара. 2 н. и 13 з.п. ф-лы, 3 табл.
Patent RU-2678391-C2 (RU)
Inventor: FUKUDA YUKO
IPC: A61F13/49
Filed: 2015-09-03
Granted: 2019-01-28
Abstract: FIELD: hygiene.SUBSTANCE: disposable pull-on diaper 10 includes absorbent core 23. Absorbent core 23 includes central absorbent portion 23c and pair of side absorbent portions 23d and has an opening as a flexural hinge between central absorbent portion 23c and each side absorbent portion 23d. Absorbent core 23 is covered with top sheet 21. Extension 21E of top sheet 21 extending to non-skin-facing-side of absorbent core 23 is joined to element 42, adjacent to outer-coating-facing-side of extension side 21E in joint 43, which is located in the transverse direction outside the bending part. Absorbent core 23 has an elastic element 25' located along its both lateral edges so that each lateral absorbent portion 23d must be bent between elastic element 25' and joint 43.EFFECT: disposable diaper in the form of underwear is disclosed.23 cl, 10 dwg
Patent RU-2691364-C2 (RU)
Title: Коричневая мешочная бумага, способная к разложению
Inventor: RENNEL WENNBERG CAMILLA
IPC: D21H11/08
Filed: 2015-12-22
Granted: 2019-06-11
Abstract: Изобретение относится к мешочной бумаге и ее производству. Способ изготовления мешочной бумаги включает этапы, на которых смешивают небеленую целлюлозу с отбеленной целлюлозой для получения смеси целлюлозы и формируют мешочную бумагу из указанной смеси целлюлозы. При этом крахмал добавляют в количестве 1-7 кг/т бумаги. Отношение массы в сухом состоянии небеленой целлюлозы к массе в сухом состоянии отбеленной целлюлозы в смеси целлюлозы составляет от 7:1 до 1:1. Полученная бумага обладает пористостью по методу Герли (в соответствии с ISO 5636-5) менее чем 25 с. Обеспечивается улучшение способности к разложению мешочной бумаги. 5 н. и 22 з.п. ф-лы, 1 ил., 5 табл.
Patent RU-2727715-C2 (RU)
Title: Слитый белок, содержащий вариант CCL3, и его применение
Inventor: NAM SU YOUN
IPC: A61P35/00
Filed: 2017-04-19
Granted: 2020-07-23
Abstract: Изобретение относится к области биотехнологии, конкретно к слитым белкам, и может быть использовано в медицине для ингибирования роста опухоли. Получен слитый белок, включающий область Fc иммуноглобулина; и вариант лиганда-3 типа CC (CCL3), имеющий последовательность SEQIDNO: 3, в которой A или AP делетированыс N-конца и аспарагиновая кислота в положении аминокислоты 27 с N-конца CCL3 заменена на аланин. В полученной конструкции слитого белка вариант CCL3 связан c Fc областью иммуноглобулина через линкер, содержащим последовательность SEQIDNO: 5, в порядке от N-конца к С-концу: вариант CCL3, линкер, область Fc иммуноглобулина. Изобретение обеспечивает получение слитого белка, обладающего связывающей активностью CCL3. 5 н. и 4 з.п. ф-лы, 5 табл., 4 пр., 6 ил.
Patent RU-2746045-C2 (RU)
Title: Crystal of pyrrolopyrimidine for obtaining jak inhibitor
Inventor: CHZHOU Chzhou
IPC: A61K31/5377
Filed: 2017-06-15
Granted: 2021-04-06
Abstract: FIELD: chemistry.SUBSTANCE: invention relates to crystal A and crystal B of acetonitrile of the compound represented by formula I, pharmaceutical compositions based on them, their use for the preparation of a medicament for the treatment or prevention of Janus kinase-mediated disease.EFFECT: crystal A and crystal B of the compound represented by formula I have high purity and good stability and are suitable for industrial production.13 cl, 6 dwg, 6 tbl, 5 ex
Patent RU-2768479-C2 (RU)
Inventor: BEKKER PETRUS
IPC: A61P35/00
Filed: 2017-06-13
Granted: 2022-03-24
Abstract: FIELD: medicine; pharmaceutics. 
     SUBSTANCE: invention relates to a method of treating pancreatic cancer in a patient, comprising administering to a patient in need thereof, an effective amount of a compound of Formula I or a pharmaceutically acceptable salt thereof, where R 1  is a halogen; R 2  is C 1-6  haloalkyl; R 3  is hydrogen or C 1-6  alkyl; R 4  is hydrogen; n is 0 and A 1  is -CH- or -N-, A 2  is -CH- and A 3  is -N-. Invention also relates to a pharmaceutical combination for treating pancreatic cancer, comprising a compound of Formula I and one or more additional therapeutic compounds selected from FOLFIRINOX or gemcitabine and paclitaxel. 
       . 
     EFFECT: effective method of treating pancreatic cancer based on the compound of Formula I. 
     11 cl, 2 dwg, 4 tbl, 3 ex
Patent RU-2756803-C2 (RU)
Title: Aerosol generating system containing several aerosol forming substrates and piercing element
Inventor: REEVELL TONY
IPC: A24F40/44
Filed: 2017-12-11
Granted: 2021-10-05
Abstract: FIELD: tobacco industry. 
     SUBSTANCE: invention relates to the tobacco industry, namely to aerosol generating systems. The aerosol generating system contains a cartridge. The cartridge contains a cartridge case. The cartridge contains solid aerosol forming substrate and liquid storage case, each of which is located in the cartridge case. The cartridge also contains liquid aerosol forming substrate located inside the liquid storage case. The cartridge includes a seal provided on the liquid storage case. The aerosol generating system contains an aerosol generating device. The aerosol generating device contains a device case that forms a cavity for placing the cartridge. The aerosol generating device contains an electric heater and a power supply unit and a controller for controlling the power supply from the power supply unit to the electric heater. The aerosol generating device includes a piercing element made with the possibility of piercing the seal when the cavity accommodates the cartridge, wherein the electric heater is located outside the piercing element.  
     EFFECT: technical result is simplifying the design of the aerosol generating system. 
     14 cl, 9 dwg
Patent RU-2751783-C2 (RU)
Inventor: SHAMUKOV STANISLAV IVANOVICH
IPC: C02F1/66
Filed: 2019-07-17
Granted: 2021-07-16
Abstract: Изобретение относится к способу очистки сточных вод. Способ очистки сточных вод включает обработку сточных вод гидроокисью кальция и связывание образовавшихся гидроокисей тяжелых металлов карбонатом кальция. Карбонат кальция вводят в массовом соотношении к гидроокиси кальция 1:4-8 в пересчете на сухое вещество, при достижении показателя рН значения 10-11 вводят флокулянт, отделяют осадок, а осветленную часть водной системы подкисляют диоксидом углерода до достижения показателя рН значения 6,5-8,5. В случае присутствия в исходной сточной воде ионов магния после обработки диоксидом углерода в водную систему дополнительно вводят флокулянт и отделяют образовавшийся осадок. Технический результат заключается в повышении степени очистки сточных вод, соответствующих нормам ПДК, установленным для вод рыбохозяйственного назначения. 2 з.п. ф-лы, 6 пр., 1 табл.
Patent RU-2761028-C2 (RU)
Title: Device for packing balls for reaction vessels for analytical device
Inventor: BROSSAR MATE
IPC: B65D83/04
Filed: 2018-04-10
Granted: 2021-12-02
Abstract: FIELD: packaging.SUBSTANCE: invention relates to a device for packing balls for reaction vessels for an analytical device, such as an automatic analytical device for analyzing chemical or biological samples. The device contains case (21) containing at least one hole (27) and used for placing balls, closing element (61) made with the possibility of moving relatively to case (21) between a closed position, in which closing element (61) closes hole (27) of case (21), and an open position, in which hole (27) of case (21) is opened in such a way that to provide the possibility of issuing balls from case (21).EFFECT: ensuring safer operation of the claimed device.11 cl, 43 dwg
Patent RU-2764991-C2 (RU)
Inventor: MARCHETTI STEFANO
IPC: B02C13/00
Filed: 2018-09-27
Granted: 2022-01-24
Abstract: FIELD: crushing. 
     SUBSTANCE: invention relates to impact crushers applicable for grinding loose material. The crusher comprises a first body defining a crushing chamber, located wherein is at least one main rotor configured to rotate around a first axis, a second body defining an inlet chamber for the material subject to crushing, in communication with the crushing chamber, located wherein is at least one secondary rotor configured to rotate around a second axis. The secondary rotor is intended for supplying the material subject to crushing into the inner part of the crushing chamber, wherein the inlet and crushing chambers are restricted by at least two side walls located substantially transversely to the first and second axes, respectively, and by at least one connecting wall placed between the corresponding side walls at least partially surrounding the corresponding rotor. The first and second axes are therein located substantially horizontally and parallel to each other. The inlet chamber is located laterally relative to the crushing chamber and said chambers are in communication by means of a connecting hole defined in the corresponding connecting walls, wherein the connecting hole is located in the lower part of the inlet chamber so that the material supplied from the secondary rotor is directed from the bottom of the inlet chamber in the direction of the crushing chamber, and the connecting wall of the inlet chamber has at least one adjustable part configured to rotate around the adjustment axis to vary the direction of intake of the material subject to crushing into the inner part of the crushing chamber. 
     EFFECT: crusher is characterised by high manufacturability. 
     15 cl, 3 dwg
Patent RU-2741599-C2 (RU)
Inventor: LEITNER ANDREAS
IPC: B01D17/06
Filed: 2017-01-27
Granted: 2021-01-27
Abstract: FIELD: chemistry. 
     SUBSTANCE: invention relates to a method of breaking at least one emulsion and separation of light and heavy phases. Method of separating at least one liquid/liquid emulsion (L/L), with water content of up to 70 wt. %, is carried out by applying at least one DC field (DC) and at least one alternating current (AC) field in the following sequence: DC-field prior to HF/AC-field action along the treated emulsion flow direction. At that at least one alternating current (AC) field is applied with electric field intensity from 2,000 to 100,000 V/m and frequency (HF) from 10,000 to 50,000 Hz. Method is carried out in an apparatus comprising at least one vessel with at least one module, at least one first electrode which is arranged along the wall of at least one vessel module, and at least one second electrode, which is located inside at least one module of vessel. 
     EFFECT: technical result is providing degree of demulsification of more than 95 % in only one device (module) in less than 5 minutes. 
     9 cl, 3 tbl, 7 ex, 13 dwg
Patent UA-72448-C2 (UA)
Title: Azabenzimidazole-based compounds, methods for their synthesis and pharmaceutical composition, method for modulating function of serine/threonine protein kinases with azabenzimidazole-based compounds, method for identifying compounds modulating functioning of serine/threonine protein kinase, method for preventing and treating serine/threonine protein kinase-related abnormal conditions with azabenzimidazole-based compounds
IPC: C07D/
Filed: 1998-09-23
Abstract: The present invention is directed in part towards methods of modulating the function of serine/threonine protein kinases with azabenzimidazole-based compounds. The methods involve cells that express a serine/threonine protein kinase, such as RAF. In addition, the invention describes methods of preventing and treating serine/threonine protein kinase-related abnormal conditions in organisms with a compound identified by the invention. Furthermore, the invention pertains to azabenzimidazole compounds and pharmaceutical compositions comprising these compounds.
Patent UA-71903-C2 (UA)
Title: Telescope boom of crane
Inventor: OKHRYMOVYCH VOLODYMYR MARKIIAN
IPC: B66C23/04
Filed: 2000-07-13
Abstract: A telescopic crane boom contains a box-shaped fixed root section, a mobile intermediate and load-bearing sections and the drive for the extension of the mobile sections. The mobile intermediate and load-bearing sections are mounted in the fixed root section with the possibility of pulling out the bases of mobile sections from the cavity of fixed section right through for the rear end of fixed section. Such execution of the invention increases the performance properties of crane.
Patent UA-62003-C2 (UA)
Title: Data processor and the method for the authentication of data in a nonvolatile memory unit
IPC: G06F21/79
Filed: 1999-09-14
Abstract: The proposed data processor contains one or more electrically programmable read-only memory units (SB1 ... SBn) and a data authentication unit (DAS). To each of the read-only memory units, a flag register (FS1 ... FSn) corresponds. The flag registers are connected to the corresponding read-only memory units via address buses (BL1 ... BLn), to a programming unit (PSQ) via a programming bus (PL), and to the authentication unit (DAS) via a common data bus. The proposed method for the authentication of data in a nonvolatile read-only memory unit consists in changing the state of the corresponding flag register (FS1 ... FSn) if the contents of the certain read-only memory unit changes, and recovering the state of the flag register after the data authentication.
Patent UA-83616-C2 (UA)
Title: Sustained-release preparations of quinolone antibiotics and method for the preparation thereof
Inventor: KANIKANTI VENKATA-RANGARAO
IPC: A61P31/04
Filed: 2001-06-13
Abstract: The invention relates to an orally dosable preparation containing a quinolone antibiotic, which releases the active ingredient in a sustained manner. A preferred embodiment concerns preparations comprising a mixture of a quinolone free base and the salt thereof. Particularly preferred are mixtures of ciprofloxacin hydrochloride and ciprofloxacin betaine.
Patent UA-76449-C2 (UA)
Title: Methods for producing camptothecin analogs and intermediary compounds
IPC: C07C225/00
Filed: 2002-02-21
Abstract: To more efficiently provide CPT, which is a starting compound for irinotecan hydrochloride and various camptothecin derivatives, by a practically usable total synthesis, a means whereby 2'-amino-5'-hydroxypropiophenone corresponding to the AB cycle moiety of the camptothecin (CPT) skeleton and a tricyclic ketone corresponding to the CDE cycle moiety thereof can be efficiently produced and thus CPT and its derivatives can be stably supplied is provided.
Patent UA-79588-C2 (UA)
Title: Method for producing crystals containing hydrated aluminum oxide from caustic mother liquors, and composition based thereon
Inventor: KUBOTH DETLEF
IPC: C01F7/145
Filed: 2002-02-02
Abstract: The invention relates to a method for producing crystals containing hydrated aluminum oxide, whereby a liquid hydrated aluminum oxide phase is brought into contact with an auxiliary agent phase containing an organic auxiliary agent having at least one of the following properties: (A) a cloud point ranging from 40 to 80 DEGREE C; (B) a viscosity ranging from 100 to 1000 mPa*s, (C) an HLB value ranging from 1 to 19; (D) an OH number ranging from 50 to 250 mgKOH/g; (E) a solidification point lower than 10 DEGREE C, and, (F) a flash point of > 70 DEGREE C in accordance with DIN 51758. The invention also relates to crystals containing aluminum hydrate, which can be obtained by using said method, to a composition containing an aluminum hydrate phase, and to the use of crystals containing aluminum hydrate and of aluminum hydrate phases.
Patent UA-81448-C2 (UA)
Title: Method for control changes of insulation conditions in distribution network
Inventor: KOSHMAN VSEVOLOD IVANOVYCH
IPC: H02H3/17
Filed: 2005-07-04
Abstract: The method for control changes in insulation condition in distribution network includes superimposition a zero-sequence to network of non-commercial frequency current. In mode with normal conditions of insulation in distribution network it is determined initial mutual values of a phase angles of non-commercial frequency current between each control sections of network. It is determined a current mutual values of those angles and compared those values with measured initial values with normal conditions of insulation. It is determined a deviation in mutual values of phase angles of imposed current and compared with given values. If deviations of mutual values of phase angles are exceeded given values, insulation resistance of some sections of controlled network has changed.
Patent UA-74316-C2 (UA)
Title: A consortium of bifidobacteria bifidobacterium bifidum vkpm аs-1688, bifidobacterium longum vkpm аs -1689, bifidobacterium adolescentis vkpm аs-1690, bifidobacteruim infantis vkpm аs -1692, bifidobacterum breve vkpm аs -1691, which are used for the preparation of sour and dairy, non-fermented products, biologically active additives, bifido-containing preparations, cosmetic and hygienic agents
IPC: C12N1/20
Filed: 2005-07-15
Abstract: The invention concerns a consortium of strains of bifidobacteria : Bifidobacterium bifidum VKPM As-1688, Bifidobacterium longum VKPM As -1689, Bifidobacterium adolescentis VKPM As -1690, Bifidobacterium infantis VKPM As -1692, Bifidobacterium breve VKPM As -1691 having high antibiotic, superoxidedismutase and expressed antioxidant activity, and can be used for the preparation of different forms of bacterial agents, agents-probiotics based thereon, functional foodstuffs, biologically active additives, non-fermented products, sour –dairy products, cosmetic and hygienic agents. Specific activity being revealed, capability to the utilization of a wide spectrum of amino acids, a high antibiotics resistance allowed to increase the stability of consortium to damaging factors of aggressive media of gastro-intestinal tract while passing bifidobacteria in gastrointestinal tract and in this manner to increase colonizing activity thereof.
Patent UA-80351-C2 (UA)
Title: Crystallizer for continuous casting metals
Inventor: LARIONOV OLEKSANDR OLEKSIIOVYC
IPC: B22D11/04
Filed: 2006-01-11
Abstract: The invention relates to the ferrous metallurgy. A crystallizer for continuous casting metals contains fastened to the steel housing with fastening pins two narrow walls with copper layer and steel cladding layer, moreover in the copper layer cylindrical and rectangular water-cooled channels are located, in which fastening pins are located out of copper and steel cladding layer, they are passed through the steel housing and fixed inside the extensions rigidly connected to the steel cladding layer and fixed inside the steel housing. The rectangular water-cooled channels are placed near the extreme lateral faces of the copper layers of narrow walls, and the cylindrical water-cooled channels are concentrated between the rectangular ducts mentioned above. The invention improves the process of crystallizer walls cooling.
Patent UA-82399-C2 (UA)
Title: Air-cushion ship
Inventor: ALEKSIEEV VIKTOR HENNADIIOVYCH
IPC: B60V1/00
Filed: 2006-04-03
Abstract: The invention relates to the shipbuilding, in particular to the design of air-cushion ships. A ship has a pontoon, a superstructure with pressuring installations and onboard sections of rigid receiver with flexible enclosure. The pontoon has built-in receiver with cuts for passage of air. The external casing of each onboard section of rigid receiver has an onboard section inclined at sharp angle toward the reference plane of the ship and parallel to the reference plane a deck section, which adjoins the appropriate board of superstructure above the level of the deck of pontoon. The compartments of dust separators of air-intake system of main engines are located downstream of built-in receiver in the superstructure along its boards. The inlets of the latter are made in onboard walls of superstructure in the space on the height between the deck of pontoon and the line of contiguity to them of the deck sections of onboard sections of rigid receiver. The invention contributes to increase of reliability and safety of operation of air-cushion ships.
Patent UA-84462-C2 (UA)
Title: Crystalline polymorphs of methanesulfonic acid addition salts of imatinib
Inventor: SZCZEPEK WOJCIECH
IPC: C07D401/04
Filed: 2005-02-04
Abstract: The invention relates to the methanesulfonic acid addition salts of Imatinib and to the processes for their preparation. In particular, the invention relates to the process for the preparation of Imatinib methanesulfonate α-crystal form. Furthermore, the invention is directed to a novel acid addition salt of 4-(4-methylpiperazin-l-ylmethyl)-N-[4-methyl-3-[(4-pyridin-3-yl)pyrimidin-2-ylamino)phenyl]benzamide with two molecules of methanesulfonic acid and the polymorphic forms thereof as well as their pharmaceutical compositions.
Patent UA-87151-C2 (UA)
Title: Method of refinishing aged surfaces
Inventor: CONNELLY BRUCE A
IPC: C08J7/046
Filed: 2005-06-23
Abstract: Compositions for refinishing aged surfaces, and methods of refinishing aged surfaces by applying compositions comprising at least one chlorinated polyolefin are disclosed.