baber/WOPTO huggingface dataset:
Patent EP-0820439-B1 (EP)
Inventor: DANVY DENIS
IPC: C07B53/00
Filed: 1997-02-04
Granted: 2000-05-03
Abstract: PCT No. PCT/FR97/00218 Sec. 371 Date Nov. 26, 1997 Sec. 102(e) Date Nov. 26, 1997 PCT Filed Feb. 4, 1997 PCT Pub. No. WO97/29086 PCT Pub. Date Aug. 14, 1997Process for the asymmetric synthesis of S-acyl derivatives of 2-mercaptomethyl-3-phenylpropanoic acid of formula (I): characterized in that it comprises the steps consisting in: a) preparing the diol (VI) by reduction of a malonic ester (V) in the presence of a hydride; b) preparing the monoacetates (VII R) or (VII S) respectively; c) subjecting these monoacetates to an oxidation in order to form the acids (IX S) or (IX R); d) saponifying the compounds (IX S) or (IX R) in order to form the hydroxy acids (X S) or (X R); e) thioacylating the hydroxy acids (X S) or (X R) with a mercapto acid R1SH (XI), according to a Mitsunobu-type reaction, in order to lead to the desired acids (I R) (I S) respectively and application to the synthesis of N-(mercaptoacyl)amino acid derivatives (II).
Patent EP-0943033-B1 (EP)
Inventor: HUOVILA JYRKI
IPC: D21F1/06
Filed: 1997-11-24
Granted: 2002-09-25
Abstract: A multi-layer headbox for a paper or board machine including stock inlet headers each providing one stock and coupled to a tube bank which in turn is coupled to a respective intermediate chamber. The stock flows from the intermediate chambers into a turbulence generator and through pipes in the turbulence generator into a slice cone to be discharged therefrom onto a forming wire. The multi-layer headbox includes distribution valves for regulating the flow of dilution water across the width of the headbox. Each distribution valve communicates with a distribution plate placed in connection with the tube bank. From each valve, the dilution liquid is distributed at the same time to all the stocks that form the different layers of the web in the multi-layer headbox at a specific position of width of the multi-layer headbox.
Patent EP-0938293-B1 (EP)
Inventor: WEI KARL SHIQING
IPC: A61Q19/10
Filed: 1997-06-17
Granted: 2001-12-12
Abstract: A process for preparing liquid personal cleansing compositions which provides enhanced perfume deposition on the skin and which provides increased on-skin fragrance longevity. The liquid personal cleansing compositions contain from about 0.01% to about 5% of a cationic polymer; from about 1% to about 80% of an anionic surfactant; from about 0.01% to about 5% of a volatile perfume; and water. The ratio of the cationic polymer to the anionic surfactant ranges from about 1:100 to about 1:2. The process involves first forming a premix comprising the cationic polymer, the volatile perfume and water, and then adding the premix to a personal cleansing base composition which comprises anionic surfactant and water.
Patent EP-0871746-B1 (EP)
Inventor: BLINKOVSKY ALEXANDER
IPC: A23L27/24
Filed: 1997-10-03
Granted: 2005-11-16
Abstract: The present invention relates to polypeptides having carboxypeptidase activity and isolated nucleic acid sequences encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid sequences as well as methods for producing the polypeptides. The present invention further relates to methods of obtaining protein hydrolysates useful as flavor improving agents.
Patent EP-0882794-B1 (EP)
Inventor: KAZUYASU NAKAMURA
IPC: C12N5/00
Filed: 1998-03-19
Granted: 2004-06-02
Abstract: A human CDR-grafted antibody which specifically reacts with ganglioside GM2, wherein said antibody comprises CDR 1, CDR 2 and CDR 3 of heavy chain (H chain) variable region (V region) comprising amino acid sequences described in SEQ ID NO:1, SEQ ID NO:2 and SEQ ID NO:3, and CDR 1, CDR 2 and CDR 3 of light chain (L chain) V region comprising amino acid sequences described in SEQ ID NO:4, SEQ ID NO: 5 and SEQ ID NO:6, and wherein at least one of the frameworks (FR) of said H chain and L chain V regions comprises an amino acid sequence selected from common sequences (HMHCS; human most homologous consensus sequence) derived from human antibody subgroups.
Patent EP-1018302-B1 (EP)
Inventor: PAVESE FRANCO
IPC: A23G9/32
Filed: 1998-11-05
Granted: 2003-10-29
Abstract: A hollow chocolate body e.g. Easter egg (2) containing a small toy or novelty has an inedible supporting shell (4) made of two e.g. polypropylene corresponding halves (6, 8) with rims (22, 24). Each rim (22, 24) has mirror-image interlocking faces (22, 24, 26, 28) by means of which the two halves are brought together or separated. The chocolate body has edible shell halves (10, 12) which may be removed from the inedible supporting shell (6, 8). The two edible shells (10, 12) are held apart by an inedible separator (18, 22, 24).
Patent EP-1010973-B1 (EP)
Inventor: DREWES ULFERT DIPL-PHYS
IPC: G01L9/12
Filed: 1998-12-14
Granted: 2001-07-18
Abstract: The measurement cell has a ceramic base body with a concave central surface (121) having a first electrode (122) and a peripheral convex surface to form an annular surface (126), on which a ceramic membrane (5) is connected, with a peripheral wedge zone of active brazing solder (10), to form a measuring chamber. The inner surface (51) of the membrane is connected to second electrode (52) contacting the wedge zone. The measurement cell has a ceramic base body with a peripheral area (11) and a concave central surface at a first surface. The concave central surface has a first electrode electrically connected to a second surface (13) and a peripheral convex surface, which has a smooth annular surface formed at its apex. A ceramic membrane lies on the annular surface and the base body and is connected to the annular surface to form a wedge zone (91) with an active brazing solder, to form a measuring chamber (M) that is leakproof under high vacuum. The smooth inner surface of the membrane that faces the base body is connected to a second electrode that contacts the wedge zone. An Independent claim is included for a method for manufacturing the measuring cell.
Patent EP-0880937-B1 (EP)
Inventor: CRITON ALINE LAURE
IPC: G01S15/89
Filed: 1998-05-28
Granted: 2002-09-04
Abstract: The method involves identifying the characteristics of a particular ultrasonic image line corresponding to that of a moving tissue. Then, the velocity of the image line is computed. Based on the computed velocity, the characteristics of the other image lines is evaluated.
Patent EP-1007549-B1 (EP)
Inventor: HAINES ADRIAN MARK
IPC: C12N5/10
Filed: 1998-02-12
Granted: 2006-12-27
Abstract: The invention encompasses a transfection complex comprising a polypeptide comprising the contiguous 29 amino acids: 6G's, 2F's, 2L's, 1W, 4R's, 2E's, 2N's, 3K's, 1T, 1S, 1A, 1Y, 1M, 1C, and 1I, and having additional cationic residues to provide a net number of positive charges of greater than or equal to 8, and an isolated nucleic acid, and methods of transfecting cells using this transfection complex. The invention also includes a polypeptide having an amino acid composition including these 29 amino acids, as well as mixtures of polypeptides in which this polypeptide is present.
Patent EP-1015687-B1 (EP)
Inventor: HAAVANLAMMI ARTO
IPC: D21F2/00
Filed: 1998-03-27
Granted: 2003-10-08
Abstract: A method and device for dewatering a paper or board web and passing the web as a closed draw from a lower wire of a web forming section, in which the web is formed between the lower wire and an upper wire, to the press section and through one or more dewatering press nips in the press section. The web is separated from the upper wire on a first suction zone or block of the suction roll, after which the web is affixed to the lower wire over a second suction zone or block of the suction roll. The web is then affixed, in a pre-press and transfer nip formed by the suction roll and a smooth-faced roll, onto the outer face of a substantially non-watering-receiving transfer belt, the web being passed on support of this belt into the first press nip. In the press nip, water is pressed out of the web into a water-receiving press felt.
Patent EP-1023663-B1 (EP)
Inventor: AGGARWAL SUDHANSHU
IPC: G06Q10/10
Filed: 1998-03-27
Granted: 2009-12-09
Abstract: Systems and methods for transmitting messages, such as real-time messages, from an entity outside a firewall to a recipient inside the firewall. The messages include the address of a bridgehead server exposed through the firewall and information identifying the recipient client. The network protected by the firewall can include one or more bridgehead servers, one or more messaging servers associated with each bridgehead server, and one or more clients assigned to each messaging server. When a bridgehead server receives a message, it resolves the address of the messaging server to which the recipient client is assigned. The message is forwarded to the messaging server and, in turn, to the recipient client. The sender of the message does not need to know the identity or address of the messaging server. Moreover, the sender, who may reside outside the firewall, does not need direct access to the messaging servers protected by the firewall in order to establish real-time communication with users inside the firewall. Thus, the messaging systems are compatible with conventional network security measures employed by many organizations. The messaging systems can be used by clients to monitor the online status of other clients or to receive notification of properties associated with other clients.
Patent EP-0979281-B1 (EP)
Inventor: ARATHOON ROBERT
IPC: C07K16/46
Filed: 1998-04-30
Granted: 2005-07-20
Abstract: The invention relates to a method of preparing heteromultimeric polypeptides such as bispecific antibodies, bispecific immunoadhesins and antibody-immunoadhesin chimeras. The invention also relates to the heteromultimers prepared using the method. Generally, the method provides a multispecific antibody having a common light chain associated with each heteromeric polypeptide having an antibody binding domain. Additionally the method further involves introducing into the multispecific antibody a specific and complementary interaction at the interface of a first polypeptide and the interface of a second polypeptide, so as to promote heteromultimer formation and hinder homomultimer formation; and/or a free thiol-containing residue at the interface of a first polypeptide and a corresponding free thiol-containing residue in the interface of a second polypeptide, such that a non-naturally occurring disulfide bond is formed between the first and second polypeptide. The method allows for the enhanced formation of the desired heteromultimer relative to undesired heteromultimers and homomultimers.
Patent EP-0988089-B1 (EP)
Inventor: ALT ECKHARD
IPC: A61N1/365
Filed: 1998-06-09
Granted: 2006-11-29
Abstract: An implantable medical interventional device responds to detection of any of a plurality of cardiac dysrhythmias in a human patient by performing an appropriate therapy which may include cardiac pacing, cardioversion or defibrillation according to the nature of the detected dysrhythmia. A first sensor detects whether and what type of dysrhythmia is occurring. A generator produces pulses and/or shocks for delivery to the patient's heart according to whether a detected dysrhythmia is bradycardia or slow pathologic tachycardia on the one hand, or fast tachycardia or fibrillation on the other hand. An optimizer in the device at all times maintains a substantial match of the cardiac pacing rate to the hemodynamic needs of the implant patient under conditions of rest and physical activity; including sensing and distinguishing periods of patient physical activity and rest, and generating a signal representative thereof to control the cardiac pacing rate accordingly. In this way, the device focuses on correction of cardiac pacing problems before they become sufficiently aggravated to require more aggressive cardioversion and defibrillation therapies.
Patent EP-0998509-B1 (EP)
Title: Systemes de semelles ameliorees en polyurethanne a expansion dans l'eau
Inventor: MADAJ EDMUND J
IPC: C08G18/08
Filed: 1998-07-14
Granted: 2001-10-31
Abstract: La présente invention concerne des articles moulés comprenant des mousses de polyuréthanne, de préférence des mousses à peau intégrée. Ces dernières sont dotées de propriétés améliorées et conviennent particulièrement dans des systèmes de semelles de chaussures. La présente invention concerne également un procédé de production de ces articles moulés. Ces articles moulés sont formés du produit de réaction de (A) un isocyanate comprenant un prépolymère stable à base de MDI liquide, contenant un MDI à allophanate modifié, avec (B) un composant de réaction d'isocyanate, en présence de (C) au moins un agent d'expansion.
Patent EP-0991855-B1 (EP)
Inventor: SCHMIDT ERWIN
IPC: F02B37/24
Filed: 1998-06-16
Granted: 2002-08-07
Abstract: A description is given of an internal combustion engine/turbocharger configuration for an internal combustion engine/turbocharger system, which configuration allows maximum braking power combined with low thermal loading.
Patent EP-1007910-B1 (EP)
Inventor: ROINE JOHANNES
IPC: G01P5/14
Filed: 1998-08-18
Granted: 2007-02-28
Abstract: The invention relates to a device and a procedure for measuring the flow of a gas or gas mixture in a flow channel (7), said device comprising a frame (10), which comprises measuring space (8), a measuring duct (6), which is mounted on the frame between the flow channel and the measuring space and which is open at both ends (2, 9) to pass the pressure wave generated by the flow from the measuring duct into the measuring space, and a measuring element (1) mounted on the frame and used to measure the pressure wave, said measuring element being disposed near the second end (9) of the measuring duct. According to the invention, the measuring duct is disposed in a substantially perpendicular orientation relative to the direction of flow the gas or gas mixture and so that it can rotate about its longitudinal axis, the measuring duct comprises a first orifice (4), which is disposed at the first end (2) of the measuring duct and faces alternately in the direction of flow and against the flow to pass a changing and cyclic pressure wave into the measuring duct, and the measuring duct comprises a second orifice (3), which is disposed in the part of the measuring duct extending into the measuring space to equalize the static pressures in the measuring space and measuring duct.
Patent EP-1019929-B1 (EP)
Inventor: SEMROV ANTON
IPC: H01H71/02
Filed: 1998-09-30
Granted: 2002-02-27
Abstract: A switch for devices, which can be arranged with a fuse with a fuse-link or without a fuse, basically consists of a housing (1) having two equal halves (2), whereat both housings differ in that the housing with a fuse is extended for the width of a bed (3) for a fuse-link (4). In both halves (2) of the housing (1) there are beds (6, 7, 8) in the shape of ribs for fixed contacts (9, 10) and a contact (11) of the fuse-link (4). A moving contact (12) is guided in rib guides (13), supported by a spring (14) and directly controlled by a rod (15). On its opposite side the rod (15) reaches into a break handle (17), with which the switch is manually broken. The handle (17) has bearings on an axle (18) lying in both halves (2) of the housing (1). The rod (15) is near the handle (17) guided in each half (2) of the housing (1) by an arch-shaped rib (21), the centre of which lies in the centre of the axle (18). In both halves (2) of the housing (1) there are arch-shaped wings (26) near the axle (18) with the centre of their arch lying concentrically to the axle (18) or to the rib (21), which are arranged with an indentation (27) as a bed of the rod (15) with the contacts open. An arch (19) is eccentrically positioned with respect to the axle (18) or to the wing (26) so that in the position of the handle (17) with the electric contacts open, one end of the arch (19) lies near the limit fence (20) between the indentation (27) and the axle (18) and the opposite end of the arch (19) lies near the limit fence (20') on the imaginary arch-shaped extension of the wing (26) via the indentation (27). In the most open position of the handle (17), the rod (15) perfectly fits into the indentation (27) and the handle (17) is free of the force of the spring (14) exerted via the rod (15).
Patent EP-1038386-B1 (EP)
Inventor: BALDWIN CURTIS KEITH
IPC: H04B7/26
Filed: 1998-06-24
Granted: 2004-05-06
Abstract: Dans un terminal (200) sans fil fixe, un émetteur-récepteur (210) est couplé à un processeur (208) d'appels qui comporte des informations d'état (218). Un raccord (202) de ligne téléphonique est couplé au processeur (208) d'appels. Un processeur (212) d'état est couplé au processeur (208) d'appels pour lire les informations d'état (218). Un générateur de signalisation (206) est couplé au processeur (208) d'état et au raccord (202) de ligne téléphonique afin de fournir des signaux qui représentent les informations d'état (218). Ces informations d'état (218) comportent des conditions de fonctionnement et des résultats d'essais dans le terminal sans fil fixe. Ces signaux comportent des signaux de type identification d'appelant et d'autres signaux sonores. Les signaux d'identification d'appelant peuvent être affichés sur un module (222) d'identification d'appelant ou un téléphone équipé d'une identification d'appelant. Une demande d'informations d'état (220) peut être entrée par un téléphone (220) connecté au terminal (200) sans fil fixe.
Patent EP-0956752-B1 (EP)
Inventor: GUETTLER FRITZ
IPC: A01B29/04
Filed: 1999-04-29
Granted: 2002-06-26
Abstract: The roller has several identical rolling rings set on an axis with a first zig-zag arrangement (13) whose tips are evenly spread over the circumference and lie on a common envelope diameter. A second zig-zag arrangement (15) is associated with the first arrangement mirror symmetric to the plane (11) at right angles to the axis but the axial extension of the second arrangement only corresponds to a fraction of the axial length (a) of the first arrangement. The second arrangement can be a toothed rim projecting axially over the support wall.
Patent EP-0981048-B1 (EP)
Inventor: GHERSON PAUL
IPC: G01N35/10
Filed: 1999-06-26
Granted: 2003-11-19
Abstract: The present invention relates to a blood clot detector which includes a pressure transducer on an aspiration line to provide output voltage data to a microprocessor corresponding to the vacuum level during aspiration. The microprocessor integrates the vacuum readings over time during the aspiration cycle to provide a pressure integral for each test sample aspiration. A pressure integral is determined for an unclotted aspiration and used as a reference for comparison with the pressure integrals of each test sample aspiration to determine whether a blood clot has interfered with the test sample aspiration. A valve (26) is provided across an analytical line (50,60) and an aspiration line (20,30) to provide selective communication between the aspiration line (20,30) and the analytical line (50,60) or to prevent such communication. Communication between the aspiration line (20,30) and the analytical line (50,60) permits transfer of a test sample from the aspiration line (20,30) to the analytical line (50,60) if the test sample is considered acceptable for sample analysis. Acceptability of the test sample for analysis is based upon a predetermined difference between the reference pressure integral and each test sample pressure integral. <IMAGE>
Patent EP-0987239-B1 (EP)
Inventor: GUERTLER CHRISTOPH DR
IPC: C07C29/00
Filed: 1999-08-24
Granted: 2003-10-29
Abstract: Alpha-substituted cycloalkenes are obtained by precious metal-catalysed metathesis of  alpha , omega -di-olefins in solvents selected from sec. or tert. alcohols, trihalomethane compounds, supercritical carbon dioxide and/or ethyl phenylacetate. A process for the production of at least  alpha -substituted ring systems of formula (II), in which the double bond may also be substituted with at least one group R, involves metathesis of a compound of formula (I) in presence of a precious metal catalyst, in a solvent selected from sec. alcohols, tert. alcohols, trihalomethane compounds, supercritical CO2 and/or ethyl phenylacetate. Y = H, acyl, alkyl, aryl or sulfonyl; R = other substituent(s); n = 1, 2, 3 or 4
Patent EP-1035051-B1 (EP)
Inventor: MADRZAK ZYGMUNT
IPC: B65H19/26
Filed: 1999-12-17
Granted: 2004-03-17
Abstract: The process for winding a paper or cardboard web (12) on to a drum (14, 14') comprises feeding it over a carrier roller (20). A nip (22) is formed between the carrier roller and drum and the web is separated from a full drum (14) and moved to a new drum (14'). The traction of the web during the transfer process between the full and new drums is controlled to keep it below the value at which uncontrolled tearing of the web could occur.  An Independent claim is included for a machine for carrying out the process.
Patent EP-1031802-B1 (EP)
Inventor: REINKE MICHAEL J
IPC: F25B39/00
Filed: 1999-02-22
Granted: 2005-08-10
Abstract: Distribution of liquid refrigerant in an evaporator having a pair of spaced headers (20,22) and a plurality of tubes (24) extending between the headers (20,22) to define a plurality of spaced refrigerant passages (42) is achieved through the use of at least one refrigerant inlet (30,32,34,36) within one of the headers (20). The inlet has a first port (49) adapted to be connected to a source of refrigerant to be evaporated, and oppositely directed second and third ports (50,54) connected to the first port (49). The second port (50) is directed away from one side (44) of the header (20) while the third port (54) is directed toward the side (44) of the header (20). <IMAGE>
Patent EP-0985565-B1 (EP)
Inventor: TIPREZ PHILIPPE
IPC: B60G15/06
Filed: 1999-09-08
Granted: 2002-11-20
Abstract: The upper fixing consists of a rod (3) with upper (20) and lower (30) domes, a limiter dome (40) and nuts (50, 60) and incorporates a two-position regulator (70) for the wheel steering error angle or transverse plane. The regulator comprises a ring (71), e.g. of plastic, fitted between the upper dome and a projecting portion (4a) of the vehicle structure (4), having an oblong outer shape and a cylindrical aperture offset relative to the ring's center along its lengthwise axis.
Patent EP-0996472-B1 (EP)
Inventor: SAMMLER ROLF
IPC: A61M60/135
Filed: 1999-04-24
Granted: 2005-02-09
Abstract: The intracardiac blood pump (10) comprises a drive section (11) and a pump section (12). A flexible pump hose (14) is connected to the pump section (12). To lay the pump hose (14) from the right atrium (21) to the pulmonary artery (26) the distal end of the pump hose (14) comprises a balloon (35) which acts as guide element in the blood flow and is entrained by the natural blood flow. This facilitates placing of the blood pump in the heart.
Patent EP-1084290-B1 (EP)
Inventor: WILJAN HARRY
IPC: D21B1/34
Filed: 1999-06-02
Granted: 2002-08-28
Abstract: A pulper device includes a vessel in which an annular flow can be generated. The flow acts upon a liquid-sold mixture located inside the vessel and effects a pulping of the same. The device also comprises a screening device for separating coarse materials from the suspension, whereby the screening device has the shape of a truncated cone. The truncated cone is provided with holes on the lateral surface thereof and can be mounted on the base of the vessel in such a way that the truncated cone points upward with the small circular surface thereof, and the lateral surface lies in an approximately tangential manner to the toroidal flow. The screening device is subdivided into different segments and these segments can be individually mounted from the external side of the vessel.