baber/WOPTO huggingface dataset:
Patent EP-2726501-A1 (EP)
Inventor: RABBANI JOSHUA
IPC: A61K38/08
Filed: 2012-06-21
Abstract: Provided is a composition comprising a peptide comprising amino acids and/or amino acid analogs comprising a continuous sequence of a sclerostin fragment comprising Tyr43 or Tyr213. Also provided is a composition comprising a peptide comprising less than about 75 amino acids and/or amino acid analogs including an amino acid or amino acid analog capable of being sulfated, where the composition is capable of inhibiting sclerostin binding to an LRP. Further provided is a composition comprising a peptide comprising less than about 75 amino acids and/or amino acid analogs including an amino acid or amino acid analog capable of being post-translationally sulfated, where the composition is capable of inhibiting binding of a protein ligand comprising a sulfation site to its binding partner. Additionally provided is a method of enhancing a Wnt signaling pathway comprising contacting an LRP5/6 receptor in the Wnt signaling pathway with either of the above-described compositions that comprise a sequence of a sclerostin fragment or is capable of inhibiting sclerostin binding to an LRP, where the tyrosine or tyrosine analog is not sulfated, in a manner sufficient to enhance the Wnt signaling pathway. Further provided is a method of treating a subject having a disease exacerbated by inhibition of a Wnt signaling pathway comprising administering either of the above-described compositions that comprise a sequence of a sclerostin fragment or is capable of inhibiting sclerostin binding to an LRP, where the tyrosine or tyrosine analog is not sulfated, to the subject in a manner sufficient to reduce the inhibition of the Wnt signaling pathway. Also, a method of inhibiting binding of a protein ligand comprising a sulfation site to its binding partner is provided. The method comprises adding the above-described composition that is capable of inhibiting binding of a protein ligand to its binding partner to the protein ligand and its binding partner in a manner sufficient to inhibit binding of the protein ligand to its binding partner.
Patent EP-2726998-A1 (EP)
Title: VERFAHREN UND VORRICHTUNG ZUR SERIELLEN DATENÜBERTRAGUNG MIT FLEXIBLER NACHRICHTENGRÖßE UND VARIABLER BITLÄNGE
Inventor: HARTWICH FLORIAN
IPC: H04L47/36
Filed: 2012-06-26
Abstract: Es wird ein Verfahren zur seriellen Datenübertragung in einem Bussystem mit mindestens zwei Busteilnehmern, die über den Bus Nachrichten austauschen, beschrieben, wobei die gesendeten Nachrichten einen logischen Aufbau gemäß der CAN-Norm ISO 11898-1 aufweisen, wobei bei Vorliegen einer ersten Kennzeichnung (EDL) das Control Field der Nachrichten abweichend von der CAN-Norm ISO 11898-1 mehr als sechs Bit umfasst und bei Vorliegen der ersten Kennzeichnung (EDL) das Datenfeld der Nachrichten abweichend von der CAN- Norm ISO 11898-1 mehr als acht Bytes umfassen kann, wobei zur Feststellung der Größe des Datenfeldes die Werte der vier Bits des Data Length Codes zumindest teilweise abweichend von der CAN-Norm ISO 11898-1 interpretiert werden, und wobei bei Vorliegen einer zweiten Kennzeichnung (BRS) die Bitlänge für wenigstens einen vorgegebenen oder vorgebbaren Bereich innerhalb der Nachricht einen gegenüber der vor dem Vorliegen der zweiten Kennzeichnung verwendeten Bitlänge verkürzten Wert annimmt, wobei der Bereich frühestens mit der zweiten Kennzeichnung beginnt und spätestens mit dem CRC Delimiter endet und die zweite Kennzeichnung (BRS) nur bei Vorliegen der ersten Kennzeichnung (EDL) auftritt und in dem abweichend von der CAN-Norm ISO 11898-1 mehr als sechs Bit umfassenden Control Field der Nachrichten erfolgt.
Patent EP-2729567-A1 (EP)
Inventor: SILVA GEORGE H
IPC: C12N15/82
Filed: 2012-07-03
Abstract: The present invention relates to a method for increasing double-strand-break induced mutagenesis at a genomic locus of interest in a cell, thereby giving new tools for genome engineering, including therapeutic applications and cell line engineering. More specifically, the present invention concerns the combined use of TALEN or meganucleases with TREX2, especially under the form of single-chain proteins.
Patent EP-2735119-A1 (EP)
Inventor: FARTHOFER MARTIN
IPC: H04M15/00
Filed: 2012-07-16
Abstract: A method of handling time information in a communications system (100) comprising: receiving a message at a proxy entity such as a P-CSCF (110, 112, 114) in an IP Multimedia Subsystem (IMS) core network (108); determining a time zone offset between a local time of a terminal and a core network time; providing the time zone offset to a network element (116) in the core network; and generating a time stamp in the network element adjusted to correspond to the local time.
Patent EP-2673040-A1 (EP)
Inventor: SONDEREGGER RALPH
IPC: A61M37/00
Filed: 2012-02-08
Abstract: An insulin infusion set (30) for use with an inserter (40) is disclosed. The infusion set (30) includes an extension set (50). The extension set (50) includes a housing (70), a base (90) and a latching device (82). The base (90) houses a base septum (120) and an infusion cannula (42). The latching device (82) releasably attaches the housing (70) to the base. When the housing (70) is attached to the base (90), a part of the housing (70) extends into and opens the base septum (120).
Patent EP-2739152-A1 (EP)
Inventor: PILZ MAURICE FREDERIC
IPC: A01N43/90
Filed: 2012-07-31
Abstract: The invention relates to compositions containing a) one or more compounds of the formula (I), in which R is a linear or branched saturated alkyl group with 5 to 11 carbon atoms or a linear or branched mono- or polyunsaturated alkylene group with 5 to 11 carbon atoms, and b) one or more alcohols that contain at least one aromatic group. The compositions are characterized in particular by an advantageous antimicrobial effect.
Patent EP-2675278-A1 (EP)
Inventor: LONG XIANGTIAN
IPC: C07D491/14
Filed: 2012-02-17
Abstract: L'invention concerne des procédés de synthèse pour préparer un composé de formule (I): Elle concerne également des procédés de synthèse pour préparer un composé de formule (XIII): L'invention concerne également des intermédiaires, des dérivés, des promédicaments utiles et des sels, des solvates et des hydrates des composés de formule (I) et de formule (XIII). Ces composés sont utiles pour traiter des maladies associées à une déficience en cofacteur à molybdène.
Patent EP-2732259-A1 (EP)
Title: Verfahren zum bestimmen der standsicherheit eines bestimmungsgemäss an einem einsatzort aufgestellten mastes
Inventor: SPALTMANN HORST
IPC: G01H13/00
Filed: 2012-07-11
Abstract: Die Erfindung betrifft ein Verfahren zum Bestimmen der Standsicherheit eines bestimmungsgemäß an einem Einsatzort aufgestellten Mastes wobei das Schwingungsspektrum des künstlich oder durch Umwelteinflüsse zum Schwingen angeregten Mastes erfasst und daraus wenigstens eine Eigenfrequenz des Mastes ermittelt wird.
Patent EP-2684712-A1 (EP)
Inventor: MIAO DONG
IPC: B29D30/48
Filed: 2012-01-30
Abstract: The pr esent invention prevents core deformation at a time of mounting a tire on a rim while cor r osi on r esi st ance and air-leak r esi st ance ar e assur ed in a tire made with a inner molding pr ocess. A bead cor e comprises axially inner and out er cor e pi eces, and a radially inner end par t of a car cass ply is held there between. The axially inner and out er bead pi eces ar e composed of a spi r al - wound body i n which a bead wire has been spirally wound and over lapped. The bead wire comprises a cor e part in which cor e st r ands have been twisted t oget her and a sheat h part in which sheat h st r ands have been twisted t oget her around the cor e part. The cor e strands and/or the sheat h st r ands comprise an errbossed st r and. The twisting direction and twisting pi t ch (Pc) of the core strands are the same as the t wi st i ng direction and t wi t chi ng pi t ch (Ps) of the sheath strands.
Patent EP-2694774-A1 (EP)
Title: Outil de coupe destiné à être utilisé dans des cavités remplies de fluide et utilisation de l'outil
Inventor: GARVIK KARL BERNER
IPC: E21B29/04
Filed: 2012-03-30
Abstract: L'invention porte sur un outil de coupe (1) agencé de façon à couper un corps allongé (8), le corps (8) s'étendant axialement dans la cavité allongée remplie de fluide (70) entourant l'outil de coupe (1) ; l'outil de coupe (1) comportant un dispositif de coupe (5) qui est agencé pour couper le corps allongé (8) complètement ou partiellement ; le dispositif de coupe (5) comprenant au moins un couteau (51, 51') avec un bord de coupe (52), le couteau (51, 51') étant agencé de façon à forcer le bord de coupe (52) complètement ou partiellement à travers le corps allongé (8) ; l'outil de coupe (1) comprenant au moins un piston mobile axialement (4) présentant une première surface de piston (43, 43') orientée à l'opposé du dispositif de coupe (5) et une seconde surface de piston (490) dirigée vers le dispositif de coupe (5) ; la seconde surface de piston (490) étant en communication fluidique avec le fluide dans la cavité allongée (70), et la section de la première surface de piston (43, 43') étant supérieure à la section de la seconde surface de piston (490) ; et une partie en forme de coin comportant une surface inclinée (54, 54') étant agencée de façon à déplacer le couteau (51, 51') contre le corps allongé (8) lorsque la partie en forme de coin est déplacée axialement le long de l'outil de coupe (1), et la première surface de piston (43, 43') étant en communication fluidique avec le fluide dans la cavité allongée (70). L'invention porte également sur une utilisation de l'outil de coupe (1).
Patent EP-2764211-A1 (EP)
Inventor: HAYES-PANKHURST RICHARD PAUL
IPC: F01C5/04
Filed: 2012-10-04
Abstract: A pump comprises a housing (10) and a rotor (11) that rotates in the housing. The housing (10) has a fluid inlet (14) and a fluid outlet (15). The rotor (11) includes two shaped surface (21, 22; 50a, 50b, 50c) radially inwardly of the housing (10) and forming with the interior surface of the housing respective chambers (23, 24; 51a, 51b, 51c) for conveying fluid from the inlet (14) to the outlet (15) on rotation of the rotor (11). A seal (12; 56) is provided between the outlet (15) and the inlet to engage the shaped surfaces (23, 24; 50a, 50b, 50c)) to prevent the passage of fluid from the outlet (15) to the inlet (14) as each shaped surface (23, 24; 50a, 50b, 50c) travels from the outlet (15) to the inlet (14). The shape of the surfaces (21, 22; 50a, 50b, 50c) provides an optimised volume for the chambers (23, 24; 51a, 51b, 51c) and the seal (12; 56) is urged into contact with the rotor (1 1) by spring arrangements (13, 39, 41, 59) that provide an even force along the axial length of surfaces (21, 22).
Patent EP-2904751-A1 (EP)
Inventor: BELLING THOMAS
IPC: H04L12/911
Filed: 2012-10-01
Abstract: There are provided measures for event based quality of service adjustment. Such measures exemplarily comprise applying a traffic management rule comprising a filter and first quality of service settings including a bandwidth amount, receiving a data packet of a service data flow, matching said data packet with said filter, and reserving, based on said bandwidth amount, bandwidth resources for a transport connection associated with said service data flow based on a matching result.
Patent EP-2620808-A1 (EP)
Inventor: WANG YONGCAN
IPC: G02F1/1343
Filed: 2012-08-15
Abstract: Embodiments of the present invention disclose an array substrate and a liquid crystal panel. An embodiment of the present invention provides an array substrate comprising a plurality of pixel units, with a pixel structure of each pixel unit comprising: a first electrode and a second electrodes, wherein the second electrode comprises a plurality of second electrode groups, each comprising a first common electrode group applied with a constant voltage and a second pixel electrode group applied with a first control voltage; the first electrode comprises a plurality of first electrode groups, each comprising a first pixel electrode group corresponding to the first common electrode group and applied with a second control voltage and a second common electrode group corresponding to the second pixel electrode group and applied with a constant voltage; the first pixel electrode group and the second common electrode group are composed of at least two sub-electrodes, respectively. The present invention can be applied in the field of display technology, such as a liquid crystal display.
Patent EP-2764282-A1 (EP)
Inventor: LAFRENZ CHRISTOPHER J
IPC: F16J15/08
Filed: 2012-10-05
Abstract: A multilayer metal gasket (40) having first (28) and second (30) functional layers. Each layer (28, 30) includes an opening (34, 38) for sealing a fluid passage or combustion chamber (26) Sealing beads (42, 44) are formed in each layer (28, 30) and, preferably, arranged to contact each other in crest-to-crest orientation to perfect a seal therebetween. A stopper feature (54) is provided to restrict compression of the sealing beads (42, 44) in use. The stopper feature (54) is arranged in a generally circular pattern and is composed of a plurality of discrete nesting embossments (56) which are closely spaced to one another but do not touch. Each discrete nesting embossment (56) is substantially identical in shape to the next adjacent discrete nesting embossment (56) but oriented approximately 180 degrees therefrom. The embossments (56) may be formed entirely on one of the functional layers (28, 30) or on both functional layers.
Patent EP-2885856-A1 (EP)
Title: Verfahren zur herstellung einer isolation eines leiters
Inventor: GRÜBEL ANDRÉ
IPC: H01B13/14
Filed: 2012-10-12
Abstract: Die Erfindung betrifft ein Verfahren zur Herstellung einer Isolation (4) eines Leiters (1), insbesondere für elektrische Maschinen, bei dem die Isolation (4) des Leiters (1) durch Extrusion eines Thermoplastes um den Leiter (1) aufgebracht wird. Dieses Verfahren ist dadurch gekennzeichnet dass die Isolation (4) des Leiters (1) in Form und Schichtdicke entlang des Leiters (1) in modulierter Weise erfolgt. Dadurch kann nach einem anschließenden Wicklungsprozess (9) die Wicklung (6) ein einheitliches äußeres Maß aufweisen. Zudem kann die Form und Schichtdicke der Isolation (4) so gestaltet werden, dass die in der Wicklung (6) innen liegenden Leiterflächen mit einer geringeren Schichtdicke isoliert werden als die, die sich an den Außenseiten der Wicklung (6) befinden.
Patent EP-2766781-A1 (EP)
Inventor: SIEFRING VERNON W
IPC: G08C17/02
Filed: 2012-10-05
Abstract: L'invention porte sur un véhicule de manipulation de matériaux, lequel véhicule effectue automatiquement des manœuvres de direction quand des objets entrent dans un environnement autour du véhicule. Une manœuvre de correction de direction est effectuée automatiquement par la direction du véhicule de façon à s'éloigner de l'objet détecté, un angle de correction de direction et/ou un taux de changement de l'angle de direction qui est réalisé pour obtenir une correction d'angle de direction désirée dépend de la distance à partir d'une coordonnée de référence associée au véhicule à partir de laquelle il est déterminé que se trouve l'objet détecté.
Patent EP-2909792-A1 (EP)
Inventor: RIME LAURENT
IPC: G06K9/20
Filed: 2012-10-16
Abstract: A method for capturing and processing an image, comprising: capturing a captured image with an image sensor; retrieving steganographic marks hidden in said captured image; processing said captured image based on said hidden marks, so as to generate a processed image; matching the processed image with a reference image from a set of reference images and superimposing elements on the captured image, depending on said reference image. A user device, comprising an image sensor suitable for capturing at least one image and a processor configured to at retrieve hidden marks in said captured image and generating a processed image based on said hidden marks retrieval and annotations processed remotely; the user device is part of a system with a remote server matching the image.
Patent EP-2782710-A1 (EP)
Inventor: QUINTARD JACQUES
IPC: B24C1/08
Filed: 2012-10-23
Abstract: The invention relates to a unit for performing working operations, using at least one jet of fluid at cryogenic temperature and at high pressure, such as liquid nitrogen. The unit includes: a source (1) of fluid at cryogenic temperature, fluidly connected to a moving tool (4) comprising one or more fluid-dispensing nozzles (11); and a protective enclosure (20) arranged around the moving tool (4) and fluidly connected to suction means (25), said protective enclosure (20) including a lower open end located on the side of the fluid-dispensing nozzle(s) (11) such as to form a suction bell around the moving tool (4). According to the invention, the unit also comprises heating means (22, 23) suitable for, and designed to produce and transfer heat to at least the lower end of the protective enclosure (20) and along at least part of the periphery of the enclosure (20), said heating means (22, 23) including at least one electric heating device (22) which is arranged around at least part of the protective enclosure (20) and which is open at the lower end of the protective enclosure (20). The invention further relates to a method for performing working operations, using a high-pressure cryogenic fluid, using the unit of the invention.
Patent EP-2716038-A1 (EP)
Inventor: ZASLAVSKY EDUARD
IPC: H04N21/658
Filed: 2012-05-29
Abstract: L'invention porte sur des procédés de rapport d'événements de téléspectateurs de système de mesure d'audience (AMS) sur un dispositif client et sur des systèmes mettant en œuvre le procédé. Le procédé comporte les étapes de réception d'au moins un message d'événement sur un dispositif client, chaque message d'événement étant un signal de données indiquant la survenue d'un événement, de traitement du ou des messages d'événement sur le dispositif client pour créer un rapport de téléspectateurs AMS, et de transmission du rapport de téléspectateurs AMS.
Patent EP-2756060-A1 (EP)
Inventor: RAND CYNTHIA L
IPC: C11D1/72
Filed: 2012-11-19
Abstract: The present disclosure provides a composition comprising at least one primary branched nonionic surfactant of Formula (I) wherein x is an integer from 1 to 11, y is an integer from 0 to 25, R 1  is an alkyl group having 1 to 5 carbon atoms, and R 2  is an alkyl group having 3 to 7 carbon atoms; and a secondary alcohol ethoxylate of Formula (II): wherein R 3  and R 4  are linear alkyl groups each having from 1 to 12 carbon atoms, and n is an integer from 1 to 20.
Patent EP-2718620-A1 (EP)
Title: Dispositif d'éclairage à modes multiples
Inventor: JOERGENSEN DENNIS
IPC: F21Y113/13
Filed: 2012-06-08
Abstract: La présente invention se rapporte à un dispositif d'éclairage comprenant un certain nombre de sources lumineuses produisant de la lumière et un certain nombre de moyens de collecte de lumière conçus pour collecter la lumière produite et pour convertir la lumière collectée en un certain nombre de faisceaux lumineux qui se propagent le long d'un axe optique. Les sources lumineuses sont réparties en un premier groupe et en un second groupe de sources lumineuses qui peuvent être individuellement commandées. Les moyens de collecte de lumière et les sources lumineuses peuvent être déplacés les uns par rapport aux autres entre une première position où les moyens de collecte de lumière collectent la lumière depuis le premier groupe de sources lumineuses et convertissent la lumière collectée en un certain nombre de premiers faisceaux lumineux, et une seconde position où les moyens de collecte de lumière collectent la lumière depuis le second groupe de sources lumineuses et convertissent la lumière collectée depuis le second groupe de sources lumineuses en un certain nombre de seconds faisceaux lumineux.
Patent EP-2605398-A1 (EP)
Inventor: NAKATA HIDEKI
IPC: H02P27/06
Filed: 2012-04-23
Abstract: A motor drive system comprising: an inverter that supplies power to a three-phase motor; and a control unit that controls switching elements of upper and lower arms included in the inverter by switching between supply control of controlling the switching elements so that alternating current is supplied to three phases of the three-phase motor and suspension control of controlling the switching elements so that the supply of current is stopped. The suspension control involves: putting and keeping, in a conduction state, a switching element of at least one upper arm each corresponding to one of one or more phases through which current flows in a direction entering the three-phase motor at a timing at which the supply of current is stopped, and putting and keeping switching elements of rest of the upper arms and switching elements of lower arms in a non-conduction state.
Patent EP-2794551-A1 (EP)
Inventor: KING STEPHEN W
IPC: C07C213/04
Filed: 2012-11-28
Abstract: La présente invention concerne un procédé amélioré pour fabriquer des composés aminés éthoxylés tels que des éthanolamines. L'amélioration comprend l'ajout d'un acide au composé aminé avant l'ajout d'oxyde d'éthylène à un réacteur dans lequel le composé aminé éthoxylé est préparé. L'amélioration réduit la concentration de sous-produits indésirables d'éthoxylate d'éther de glycol et/ou d'éther de vinyle qui peuvent contribuer à des propriétés indésirables, telles que la couleur et le moussage, des composés aminés éthoxylés.
Patent EP-2726613-A1 (EP)
Inventor: CHIN DANIEL
IPC: C12N15/113
Filed: 2012-06-28
Abstract: The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of a Hepatitis B Virus gene. The invention also relates to a pharmaceutical composition comprising the dsRNA or nucleic acid molecules or vectors encoding the same together with a pharmaceutically acceptable carrier; methods for treating diseases caused by Hepatitis B Virus infection using said pharmaceutical composition: and methods for inhibiting the expression of a Hepatitis B Virus gene in a cell.
Patent EP-2931407-A1 (EP)
Inventor: PEICHEL JOHN THOMAS
IPC: B01D65/08
Filed: 2012-12-14
Abstract: A filtering module, for example a nanofiltration or reverse osmosis module, is made of membranes arranged in a stack with flat sheets of feed channel spacer and permeate carrier. The stack has packs formed of two membrane sheets sealed on four sides and enclosing a permeate carrier. The packs alternate with sheets of feed channel spacer through the thickness of the stack. One or more permeate-collecting pipes pass through the thickness of the stack. The sheets of feed channel spacer have seals along two sides and around the permeate-collecting pipes. A module is formed by placing one or more stacks in a pressure vessel with a seal between the stack and the pressure vessel at a downstream end of the stack.
Patent EP-2849843-A1 (EP)
Inventor: CURTIN BARRY D
IPC: G16H20/30
Filed: 2012-12-21
Abstract: A defibrillator system (400) optimizes the timing and manner of applying a defibrillator charge to a patient based upon data provided to the defibrillator (410) from a utility module (455) or one or more external devices (494). A parameter module (460) on the utility module provides the defibrillator with patient parameter information. Devices external to the utility module may provide the utility module with coaching data that the utility module may pass through to the defibrillator as a proxy to the external devices. The utility module may also provide external devices with patient data that the utility module may pass through to the external devices as a proxy to the defibrillator on a scheduled or other basis. The utility module may additionally provide a reserve of power (415) to enable defibrillators to be used where power is unavailable and to enable defibrillators to deliver multiple charges more readily anywhere, anytime.