Patent SG-11201807402P-A (SG)
Title: Compositions
Inventor: CROWE SCOTT
IPC: A61K38/00
Filed: 2017-03-31
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property -, Organization 1111111101111011101010111110101111 10111 0111 100111111101 11101111111110111 OE 1111 International Bureau ... .... ..Yjd (10) International Publication Number (43) International Publication Date ..... ...,/ WO 2017/167997 Al 5 October 2017 (05.10.2017) WIP0 I PCT (51) International Patent Classification: ness Park, Cambridge Road, Cambridge Cambridgeshire A61K 9/14 (2006.01) A61K 9/20 (2006.01) CB22 3GN (GB). FRODSHAM, Mike; c/o Quay Pharma- A61K 38/00 (2006.01) A61K 9/50 (2006.01) ceuticals Limited, Quay House 28 Parkway, Deeside Indus - A61K 9/16 (2006.01) A61K 31/00 (2006.01) trial Park, Deeside Clwyd CH5 2NS (GB). (21) International Application Number: (74) Agents: RUSCOE, Peter et al.; Sagittarius IP, Three PCT/EP2017/057775 Globeside, Fieldhouse Lane, Marlow Buckinghamshire SL7 1HZ (GB). (22) International Filing Date: 31 March 2017 (31.03.2017) (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, (25) Filing Language: English AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, (26) Publication Language: English BZ, DO, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, (30) Priority Data: HN, 16163178.3 31 March 2016 (31.03.2016) EP KP, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, (71) Applicant: VHSQUARED LIMITED [GB/GB]; 1 Lower MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, Court, Copley Hill Business Park, Cambridge Road, Bab- NI, NO, raham, Cambridge Cambridgeshire CB22 3GN (GB). RU, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, (72) Inventors: CROWE, Scott; c/o VHsquared, 1 Lower ZA, ZM, ZW. Court, Copley Hill Business Park, Cambridge Road, Cam- _ bridge Cambridgeshire CB22 3GN (GB). WEST, Mike; (84) Designated States (unless otherwise indicated, for every c/o VHsquared, 1 Lower Court, Copley Hill Business Park, kind Cambridge Road, Cambridge Cambridgeshire CB22 3GN GM, of regional protection available): ARIPO (BW, GH, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, — _ (GB). ROBERTS, Kevin; c/o VHsquared, 1 Lower Court, TZ, rt, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, Copley Hill Business Park, Cambridge Road, Cambridge TJ, TM), Cambridgeshire CB22 3GN (GB). CARLTON, Tim; c/o DK, European (AL, AT, BE, BG, CH, CY, CZ, DE, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, = VHsquared, 1 Lower Court, Copley Hill Business Park, LV, Cambridge Road, Cambridge Cambridgeshire CB22 3GN SM, (GB). MAGGIORE, Luana; c/o VHsquared, 1 Lower GW, KM, ML, MR, NE, SN, TD, TG). Court, Copley Hill Business Park, Cambridge Road, Cam- Published: MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, = — bridge Cambridgeshire CB22 3GN (GB). CUBITT, Mari- - on; c/o VHsquared, 1 Lower Court, Copley Hill Business with international search report (Art. 21(3)) = Park, Cambridge Road, Cambridge Cambridgeshire CB22 — with sequence listing part of description (Rule 5.2(a)) = 3GN (GB). WHALE, Gary; c/o VHsquared, 1 Lower with information concerning incorporation by reference of Court, Copley Hill Business Park, Cambridge Road, Cam- missing parts and/or elements (Rule 20.6) bridge Cambridgeshire CB22 3GN (GB). WAHLICH, John; c/o VHsquared, 1 Lower Court, Copley Hill Busi- _ = = = = = Il IN C:r C:r IN 1-1 IN 1-1 © (54) Title: COMPOSITIONS ei r .-. ) (57) : There is provided a solid pharmaceutical composition for delivering by oral administration a pharmaceutically active '° binding polypeptide to a region of the intestinal tract comprising a compressed core, wherein the compressed core comprises a phar - .,- maceutically active binding polypeptide and wherein the compressed core is coated with a pH sensitive enteric coating.