baber/WOPTO huggingface dataset:
Patent JP-3910635-B2 (JP)
IPC: A61P3/06
Filed: 1996-06-05
Granted: 2007-04-25
Abstract: The present invention provides a method for increasing HDL cholesterol in a mammal by stimulating an immune response that inhibits the function of CETP. Such an immune response can be induced by immunizing with CETP or fragments of CETP (together termed "CETP Peptides") which contain an epitope capable of stimulating such a response. The peptides can be conjugated to a carrier, such as KLH or ovalbumin, in order to increase immunogenicity. Adjuvants can also be administered.
Patent JP-3474574-B2 (JP)
IPC: A61K47/48
Filed: 1994-06-14
Granted: 2003-12-08
Abstract: The present invention relates to disulfide-stabilized recombinant polypeptide molecules which have the binding ability and specificity for another peptide, such as the variable region of an antibody molecule. Methods of producing these molecules and nucleic acid sequences encoding these molecules are also described. In particular, the invention discloses Fv antibody fragments stabilized by a disulfide bond connecting the VH and VL regions of the Fv fragment. The alpha and beta chains of T cell receptors may be similarly stabilized by means described in the invention.
Patent JP-3124031-B2 (JP)
IPC: F04D13/08
Filed: 1992-01-10
Granted: 2001-01-15
Abstract: PCT No. PCT/AU92/00008 Sec. 371 Date Jul. 7, 1993 Sec. 102(e) Date Jul. 7, 1993 PCT Filed Jan. 10, 1992 PCT Pub. No. WO92/13243 PCT Pub. Date Aug. 6, 1992A thermoelectric system (10) includes a thermoelectric module (12) and volume defining manifolds (14) attached to opposed faces of the module (12). Fluid pumps (44) circulate fluid from remote heat exchangers (46) and through the manifolds (14). The module (12) provides opposing hot and cold faces with respective manifolds (14) attached thereto. The cold faces and manifolds (14) are connected to a first fluid pump (44) and heat exchanger (46), and the hot faces and manifolds (14) are connected to a second fluid pump (44) and heat exchanger (46). The manifolds (14) include an outer wall spaced from the module (12) and side walls abutting the respective faces thereby defining an open face wherein the side walls and outer wall and outer face define a volume for receiving fluid.
Patent JP-3343348-B2 (JP)
IPC: A61N1/30
Filed: 1992-03-30
Granted: 2002-11-11
Abstract: Methods for delivering therapeutic agents by iontophoresis with reduced or mitigated sensation are disclosed. The methods generally involve the step of delivering therapeutic agent by iontophoresis in the presence of an intentionally added sensation reducing amount of a multivalent ion. Preferred multivalent ions useful to mitigate sensation are calcium, magnesium, phosphate and zinc.
Patent JP-4338057-B2 (JP)
IPC: A01N63/20
Filed: 1997-08-27
Granted: 2009-09-30
Abstract: A method for killing pests (e.g. insects) comprising administering material from Xenorhabdus species (e.g. X. nematophilus) such as cells or supernatants orally to the pests, either alone or in conjunction with Bacillus thuringiensis or pesticidal materials derived therefrom. Also disclosed is an isolated pesticidal agent (and compositions comprising the same) characterized in that it is obtainable from cultures of X. nematophilus or mutants thereof, has oral pesticidal activity agent Pieris brassicae, Pieris rapae and Plutella xylostella, is substantially heat stable to 55° C., is proteinaceous, acts synergistically with B. thuringiensis cells as an oral pesticide and is substantially resistant to proteolysis by trypsin and proteinase K. DNA encoding pesticidal activity is also disclosed.
Patent JP-3042880-B2 (JP)
IPC: F16L55/165
Filed: 1991-06-27
Granted: 2000-05-22
Abstract: An existing pipeline (1) is relined by introducing an inner tube (2) of thermoplastic material, particularly of polyethylene terephthalate, and enlarging thereafter its diameter until the inner tube (2) tightly engages the inner wall of the pipeline (1). During the introduction of the inner tube (2) the ratio of the external diameter of the inner tube (2) to the internal diameter of the pipeline is less than 0.6. This method is particularly suitable for relining existing pipelines compressing in their wall substances which can be released into a medium transported through such a pipeline, e.g. a pipeline of lead for drinking water transport. An installation for introducing an inner tube (2) into a pipeline (1) comprises a coupling piece (3) having an inlet (16) for a pressurized fluid and a vent opening (7), and a bush (14) for fixing the inner tube (2).
Patent JP-3162073-B2 (JP)
IPC: C07D241/04
Filed: 1993-02-16
Granted: 2001-04-25
Abstract: The (6S &cir& _) stereoisomer of folinic acid is obtained in high optical purity by salification of (R, S) folinic acid with di- or polyamines and subsequent selective crystallization of the desired diastereomeric salt.
Patent JP-4335316-B2 (JP)
IPC: A61K35/34
Filed: 1997-09-19
Granted: 2009-09-30
Abstract: Materials which contain polysaccharide chains, particularly alginate or modified alginate chains. The polysaccharide chains may be included as side chains or auxiliary chains from a backbone polymer chain, which may also be a polysaccharide. Further, the polysaccharide chains may be cross-linked between side chains, auxiliary chains and/or backbone chains. These materials and non-modified or otherwise modified alginate materials are advantageously modified by covalent bonding thereto of a biologically active molecule for cell adhesion or other cellular interaction. Processes for preparation of these alginate materials and methods for using them, particularly for cell transplantation and tissue engineering applications.
Patent JP-3150967-B2 (JP)
IPC: A61P31/04
Filed: 1990-10-09
Granted: 2001-03-26
Abstract: The present invention details the use of double-stranded RNA (dsRNA) for reactivation of natural defense systems within human cells, tissues and organs reduced to inadequate function subsequent to injury. Specific treatments for acquired immune deficient states are described. dsRNA stimulates the release of an immune lymphokine, tumor necrosis factor (TNF) and protects against the toxic effects associated with increased TNF levels.
Patent JP-3512802-B2 (JP)
IPC: H01M8/02
Filed: 1994-04-20
Granted: 2004-03-31
Abstract: An electrocatalyst material for use in an acid electrolyte environment, comprising platinum or a platinum alloy supported on a conductive support, and gold, gives unexpectedly improved performance over similar electrocatalysts without gold.
Patent JP-3078017-B2 (JP)
IPC: D21D5/00
Filed: 1996-02-09
Granted: 2000-08-21
Abstract: This invention relates to a process for recovering raw materials from a stream of residual or collected material (R) which comprises a plurality of different materials and which arises during the manufacture of paper (P) in a paper mill (1) and/or in a material processing installation (2) and/or in a paper machine (3) and which is discharged therefrom, wherein the stream of residual or collected material (R) is fed to an installation (4) for separating at least one fiber fraction contained in the stream of residual or collected material (R) via a screening operation and for separating an ash fraction (A) comprising black particles. In order to achieve cost-effective recovery of the raw materials, it is specified according to the invention firstly that the separation of the fiber fraction via screening is effected, in accordance with the process, before the separation of the ash fraction (A) containing black particles, and secondly that the paper fraction is classified, depending on the desired paper size, into at least two different classes of fiber, preferably into long fibers (LF), short fibers (KF) and/or broken fibers (BF), by a screening operation in each case.
Patent MD-3432-B2 (MD)
Title: Alcoholic brandy-type drink
Inventor: PARASCA PETRU
IPC: C12H6/02
Filed: 2005-10-31
Abstract: The invention refers to the wine industry, namely to a process for producing aged strong alcoholic brandy-type drinks. The alcoholic brandy-type drink comprises grape distillate aged at least 6 months on heat-treated oak stave, sugar syrup, caramel, rectified ethyl alcohol, softened water, tincture of nuts in the milky-wax ripeness stage aged at least 6 months on heat-treated oak stave, the components being taken in the following ratio, vol. % :grape distillate�48,0à49,0nut tincture��0,2à0,3sugar syrup��0,8à1,2caramel���0,1à0,2rectified ethyl alcohol and softened water�the rest, up to the strength of 40?0,3 vol. %.the grape distillate and nut tincture ageing being carried out on oak stave heat-treated at different temperatures: 45à50% at 115à125?C during 10à15 days, 35à40% at 145à155?C during 8à12 hours, 10à15% at 1260à165?C during 1à2 hours; the nut tincture is obtained by nut maceration in the milky-wax ripeness stage on grape distillate in two stages: on the first stage the maceration is carried out in the ratio of 1:10 and on the second stage in the ratio of 1:5.
Patent ES-2325349-B2 (ES)
Title: Procedimiento y sistema para el tratamiento de aguas contaminadas con metales pesados.
Inventor: ALBA ELIAS FERNANDO
IPC: C02F3/32
Filed: 2007-07-31
Granted: 2010-04-16
Abstract: Procedimiento y sistema para el tratamiento de
aguas contaminadas con metales pesados. 
     El procedimiento comprende la extracción de
metales pesados en aguas contaminadas,  habitualmente provenientes
de procesos industriales, mediante la actividad  de atrapamiento
biológico que desarrolla el micelio del hongo. Este micelio  del
hongo está presente en el sustrato empleado en el cultivo de
champiñones  o de otros hongos comestibles. La invención también se
refiere a un sistema  para llevar a cabo dicho procedimiento.
Patent ES-2325524-B2 (ES)
Title: Molde modular para obtencion de prototipos rapidos.
Inventor: LORENZO YUSTOS HECTOR
IPC: B29C33/50
Filed: 2008-07-10
Granted: 2010-03-01
Abstract: Molde modular para la obtención de prototipos
rápidos, que está subdividido  en al menos dos partes acoplables
entre sí. 
     Cada una de las partes tiene: una impronta
flexible interna que define,  al acoplar entre sí las partes que
conforman el molde, al menos parte de  la cavidad de la pieza a
obtener; una contraforma de naturaleza rígida,  que aloja a al menos
parte de la impronta flexible y sirve como soporte  de la misma; una
placa rígida externa que define la superficie exterior  de la parte
correspondiente del molde y constituye un elemento reutilizable  e
intercambiable entre moldes para piezas diferentes; y una serie de
elementos  intermedios rigidizadores y de acoplamiento, dispuestos
entre la impronta  flexible y la placa posterior rígida, parte de
los cuales, al menos, son  reutilizables e intercambiables entre
moldes para piezas diferentes.
Patent ES-2350347-B2 (ES)
Title: Sistema de almacenamiento de aire frio para uso en centrales termicas.
Inventor: MONTES PITA MARIA JOSE
IPC: F02C6/16
Filed: 2010-09-30
Granted: 2011-10-21
Abstract: Sistema de almacenamiento de aire frío para uso
en centrales térmicas que necesiten aire, particularmente para la
combustión, constituido por un compresor (12) de aire que funciona
nocturnamente, y que inyecta el aire comprimido en el primario de un
intercambiador (24), en el que se enfría por la acción del propio
aire nocturno, que fluye por el secundario del intercambiador (24);
siendo inyectado el aire comprimido frío en un depósito o tanque
(17), desde el cual se puede descargar el aire almacenado cuando la
temperatura del aire ambiental suba por encima de un punto de
consigna, inyectándose el aire descargado en el compresor (4) del
ciclo termodinámico de la central, lo que mejora ostensiblemente las
prestaciones de éste.
Patent ES-2413908-B2 (ES)
Title: Estaciones de pulverización para control de temperatura en calderas solares
Inventor: PLOTKIN ANDREW
IPC: F24S90/00
Filed: 2010-02-08
Granted: 2014-07-25
Abstract: Caldera para un receptor solar que incluye una pluralidad de paneles de receptores solares. Los paneles están conectados de manera fluídica entre sí mediante un circuito de vapor. Por lo menos una estación de pulverización está en comunicación fluídica con el circuito de vapor y está configurada y adaptada para proporcionar una pulverización de enfriamiento de la temperatura al circuito de vapor con el fin de controlar las temperaturas de los paneles.
Patent ES-2610511-B2 (ES)
Title: Procedimiento para preparar un composite cementiceo, morteros y hormigones micro-nanoestructurados de larga vida en servicio, que comprenden dicho composite
Inventor: FERNANDEZ LOZANO JOSÉ FRANCISCO
IPC: C04B28/00
Filed: 2015-09-25
Granted: 2017-10-09
Abstract: Procedimiento para preparar un composite cementíceo, morteros y hormigones micro-nanoestructurados de larga vida en servicio, que comprenden dicho composite.#La presente invención se refiere a un procedimiento para la preparación de un composite cementíceo que comprende:#1) una primera etapa de acondicionamiento de nanopartículas de sílice, en la que se calientan a una temperatura entre 85-235°C, durante un intervalo de tiempo suficiente para conseguir un porcentaje de humedad máximo del 0,3% respecto al peso total del material resultante de esta primera etapa,#2) una etapa de dispersión en seco en la que las partículas acondicionadas según la etapa 1) se dispersan sobre cemento y en la que se usan bolas inertes de molienda,#3) una etapa de acondicionamiento del composite cementíceo obtenido en la etapa 2), en la que se separan las bolas de molienda utilizadas del composite cementíceo obtenido,#al composite obtenido, a derivados de cemento que comprenden este composite, preferentemente morteros y hormigones, a su método de preparación y al uso de estos materiales en la industria.
Patent IE-S87060-B2 (IE)
Title: Butyraldehyde oxime drug itermediates synthesis method
Inventor: RUER LIAO
IPC: C07C251/00
Filed: 2018-08-16
Abstract: The present invention discloses drug intermediates butyraldehyde oxime drug intermediates synthesis method, comprises the following steps: 1-chlorobutane and potassium sulfate solution were added to the reaction vessel, raised the temperature of the solution, controlled the stirring speed, added aqueous solution and ethyl vinyl ether solution, added bromosuccinic acid imide in batches, continued to react; then added chromium acetate powder, raised the temperature of the solution, continued to react, washed with potassium bromide solution, washed with hexafluoroethane solution, recrystallized in chloropropene solution, dehydrated with dehydration, got the finished product butyraldehyde oxime.
Patent AU-2001244903-B2 (AU)
Title: Inhaler
Inventor: RASMUSSEN JORGEN
IPC: A61M15/00
Filed: 2001-03-16
Granted: 2005-05-05
Abstract: An inhaler for delivery of medicament from a canister (2) which is compressible to deliver a dose of medicament. The inhaler comprises: a housing (1) for holding a canister (2); a canister engagement lever (10) engageable with a canister (2) held in the housing to compress the canister (2); a loading mechanism for loading a resilient loading element (7) which is arranged, when loaded, to bias the canister engagement lever (10) to compress the canister (2); and a triggering mechanism arranged to hold the canister engagement lever (10) against compression of the canister (2) and triggerable to release the canister engagement lever (10). The linkage between the resilient loading element (7) and the canister engagement lever (10) is arranged to reduce the force applied by the canister engagement lever (10) to the triggering mechanism when held by the triggering mechanism.
Patent AU-2001278992-B2 (AU)
Title: System and method for automatic placement of labels for interactive graphics applications
Inventor: AZUMA RONALD
IPC: G06T11/60
Filed: 2001-07-24
Granted: 2006-03-02
Abstract: A method and apparatus for positioning labels on a graphical display, which, in an illustrative embodiment, can include labels for aircraft icons in an air traffic control system's computer graphics display. The present invention advantageously identifies clusters of overlapping labels and objects, and calculates non-overlapping label positions on a cluster by cluster basis. In another aspect of the present invention, the movement of labels is accomplished in a smooth, incremental fashion so that cognitive distraction to the user of the graphical display terminal is kept to a minimum.
Patent AU-2002226955-B2 (AU)
Title: Pharmaceutical dosage form with multiple coatings
Inventor: NEWBY DANIEL GARY
IPC: A61K31/606
Filed: 2001-11-23
Granted: 2006-04-27
Abstract: The present invention relates to a pharmaceutical composition in a solid unit dosage form for oral administration in a human or lower animal comprising: a. a safe and effective amount of a therapeutically active agent; b. an inner coating layer selected from the group consisting of poly(methacrylic acid, methyl methacrylate) 1:2, poly(methacrylic acid, methyl methacrylate) 1:1, and mixtures thereof; and c. an outer coating layer comprising an enteric polymer or film coating material; wherein the inner coating layer is not the same as the outer coating layer; wherein if the inner coating layer is poly(methacrylic acid, methyl methacrylate) 1:1 then the outer coating layer is not poly(methacrylic acid, methyl methacrylate) 1:2 or is not a mixture of poly(methacrylic acid, methyl methacrylate) 1:1 and poly(methacrylic acid, methyl methacrylate) 1:2; and wherein the inner coating layer and the outer coating layer do not contain any therapeutically active agent. This invention further relates to a method of maintaining the desired site of delivery of a therapeutic agent in the gastrointestinal tract by administering the above compositions to a human or lower animal.
Patent AU-2002229873-B2 (AU)
Title: Provisional dental implant for preparing an alveolus
Inventor: GAULT PHILIPPE
IPC: A61C19/06
Filed: 2002-01-11
Granted: 2007-01-04
Abstract: The present invention relates to a temporary dental implant intended to prepare the alveola of an extracted tooth so that a selected dental implant can be inserted later. It also involves the use of this temporary dental implant from a functional and/or aesthetic point of view. It has, in addition, as its object kits, methods and tools, notably resin models, that can be used for the application or preparation of the above implants.
Patent AU-2002251029-B2 (AU)
Title: Coated biomedical devices
Inventor: HUGUES TIMOTHY CHARLES
IPC: A61L27/00
Filed: 2002-02-27
Granted: 2007-01-04
Abstract: The present invention is concerned with biomedical device comprising (a) a biocompatible organic or inorganic bulk material and (b) a coating comprising polymerizable carbon-carbon double bonds covalently attached to at least part of the bulk surface. The biomedical devices of the invention are radiation sensitive and may be used, for example, as ready-to-use corneal onlay in ophthalmic surgery.
Patent AU-2002254855-B2 (AU)
Title: Method of separating suspension, in particular for waste water treatment, and an apparatus for performing the same
Inventor: MACKRLE VLADIMIR
IPC: C02F3/34
Filed: 2002-05-07
Granted: 2007-06-14
Abstract: Arrangement for separating suspension, in particular for treatment of wastewater. A flocculating suspension is separated from the liquid by filtration in a fluidized layer in a sludge blanket, wherein the flocks are created from the separated suspension and fluidization is maintained by the rising stream of liquid while liquid with suspension enters the fluidized layer from the bottom and the liquid freed from suspension is discharged above the surface of the sludge blanket represented by the interface between the fluidized layer and the liquid without suspension. Thickened separated suspension in the form of flocks from a sludge blanket is withdrawn from a zone of the fluidized layer the velocity of upward flow in the fluidized layer decreasing in the upward direction.
Patent AU-2002301988-B2 (AU)
Title: Thiol compound, method for producing the same and optical product comprising the same
Inventor: OKUBO TSUYOSHI
IPC: C08G75/04
Filed: 2002-11-14
Granted: 2004-04-22
Abstract: The invention relates to a novel thiol compound useful as a starting material for optical materials that have a high refractive index and a high Abbe's number; and a method for efficiently producing the same. The thiol compound is represented by the general formula (1) : <CHEM>  wherein n is 1 or 2, and the method for producing a thiol compound represented by the general formula (1) comprises the use of 1,3,5-trithiane having a methylene or vinyl group simultaneously at the 2,4,6-positions thereof as an intermediate.
Patent AU-2002341266-B2 (AU)
Title: Use of HMGB1 for the activation of dendritic cells
Inventor: BIANCHI MARCO
IPC: C12N5/0784
Filed: 2002-09-25
Granted: 2007-11-15
Abstract: Use of the protein HMGB1 or a variant or fragment thereof or a polynucleotide encoding therefor for inducing the activation of an antigen presenting cell (APC).
Patent AU-2003288169-B2 (AU)
Title: Synergistic combination comprising roflumilast and (R,R) -formoterol
Inventor: WOLLIN STEFAN-LUTZ
IPC: A61P11/00
Filed: 2003-11-26
Granted: 2010-01-07
Abstract: The invention relates to the combined administration of roflumilast and R,R-formoterol for the treatment of respiratory tract disorders.
Patent AU-2003291412-B2 (AU)
Title: Material mover having a fluid film reservoir
Inventor: JOHNSON RAYNOR A
IPC: B60V1/06
Filed: 2003-11-10
Granted: 2007-01-04
Abstract: A material mover includes substantially rectangular top and bottom sheets connected to perimeter sidewalls defining at least one chamber. The bottom sheet is perforated with orifices at least in a central portion and has a greater width than that of the top sheet at least in middle and lower regions of the top and bottom sheets. A plurality of partition members connect at least portions of the top and bottom sheets to one another within the chamber, extend parallel to lateral edges of the top and bottom sheets, and are spaced from the perimeter sidewalls. A fluid weir is defined along an outer periphery of the bottom sheet to provide a fluid film reservoir at least under the central portion of the bottom sheet including the orifices. Fluid in the fluid reservoir is substantially contained by the fluid weir.
Patent AU-2004202407-B2 (AU)
Title: Print engine controller with dithering and compositing circuitry
Inventor: WALMSLEY SIMON ROBERT
IPC: B41J2/205
Filed: 2004-06-01
Granted: 2006-01-05
Abstract: A print engine/controller (10) to drive an ink drop print head has an interface (22) at which to receive compressed page data, decoders (28,88) to decode respective types of image planes in the received compressed page data, and a half-toner/compositor to (29) composite image plane data, the half-toner/compositor including a dot merger unit (58) taking bits from the respective planes as inputs and a color mask register (61) holding masking bits in number equal to the number of image planes, respective input bits to the dot merger unit being ANDed with respective color mask register bits and the resultant bits Ored together to form an output bit in a channel for which there is an ink at the print head. The respective planes to the dot merger unit may include three contone color planes and a high resolution spot plane, and the color mask register is loaded with bits that are selected to place the high resolution spot plane into any one of the respective color channels at the print head. A fixative channel may be generated from any one or more of the respective planes and selected by what bits are loaded to the color mask register. The respective planes to the dot merger unit (58) may include three contone color planes and a bi-level spot plane and the color mask register (61) may be loaded with bits that are selected to split a K plane into C, M, and Y channels for output to a print head without K.