baber/WOPTO huggingface dataset:
Patent IE-39908-L (IE)
Title: Polymer supported synthesis of penicillins and¹cephalosporins
IPC: C08F8/34
Filed: 1974-07-30
Abstract: 1482922 Polymer-drug reaction products GLAXO LABORATORIES Ltd 30 July 1974 [31 July 1973] 36386/73 Headings C3P and C3R [Also in Division C2] Carboxylic acid derivatives of penicillin or cephalosporin are attached via the carboxy groups by ester linkages to reactive polymers, each polymer molecule carrying a plurality of drug molecules. Suitable reactive polymers include (1) styrene/divinyl benzene copolymers containing diazomethylene groups, prepared by reacting the copolymer first with acetyl, benzoyl or alkoxy-substituted benzoyl chloride, then converting the acyl derivative to the hydrazone derivative by reaction with hydrazine, and finally oxidizing this, e.g. with peracetic acid; (2) a polymer containing benzhydrylamine groups prepared by reductive amination of benzoylated styrene/divinyl benzene copolymer, reaction with the drug being effected in the presence of nitrosyl chloride which nitrosates the amine groups; (3) styrene/ divinyl benzene copolymer substituted with alpha-hydroxybenzyl groups; (4) atyrene/allyl alcohol copolymer; (5) the diazomethylene polymer prepared by oxidizing poly(benzyl) to form poly(benzoyl), converting this to the hydrazone form by reaction with hydrazine, and oxidizing the hydrazone with peracetic acid; and (6) the diazomethylene polymer prepared by a similar sequence starting from styrene/methyl vinyl ketone/divinyl benzene copolymer. Numerous different penicillin and cephalosporin acids which may be so reacted are specified. The purpose of the above polymer attachment is to immobilize the drug so that further reactions may be effected thereon. Exemplified reactions include (i) oxidation of sulphide to sulphoxide groups; (ii) reduction of sulphoxide to sulphide groups; (iii) de-acylation of N-acylated compounds; (iv) re-acylation with different groups, e.g. with thienylacetyl chloride; (v) ring expansion of penicillin acid 1-oxide compounds to corresponding cephalosporin compounds; and (vi) reaction of 3- hydroxymethyl groups with isocyanates. The thus-modified polymer-drug reaction products may be treated to release the modified drug, e.g. with formic acid or trifluoroacetic acid-for drugs so obtained, see Division C2.
[GB1482922A]
Patent IE-38420-L (IE)
Title: Endoprosthetic knee joint.
IPC: A61F2/38
Filed: 1973-09-18
Abstract: 1448818 Prosthetic knee joints NATIONAL RESEARCH DEVELOPMENT CORP 18 Sept 1973 [18 Sept 1972] 43151/72 Heading A5R An artificial knee joint comprises a femoral component, Fig. 5, having a generally concave bearing surface and a tibial component 2, Fig. 7, having a generally convex bearing surface adapted to engage the concave bearing surface, said convex bearing surface being generally saddle-shaped with a pommel 4d at one end and in longitudinal section having at least one portion which diverges from the adjacent portion of the concave member. In use the longitudinal axis of the saddle-shaped member lies along a front-to-back axis of the knee joint, the pommel 4d being located posteriorly. In a position (shown dotted bottom left of Fig. 5) to facilitate standing, the part 4a-4b of the upper surface 4 of the tibial component engages the lower surface of the femoral component between the regions 3a and 3b, in which regions the two surfaces are complementary in both longitudinal and lateral shaping, thus providing a relatively large area of contact maximising the stability of the joint. The bearing surfaces diverge from each other beyond points 3b and 4b and in a second position (dotted right Fig. 5), the pommel 4d engages the femoral member as in a ball-and-socket joint. Relative rotation in the horizontal plane is allowed in this position. The surfaces of both the femoral and the tibial components are extended into flared portions along the longitudinal side peripheries. The lower surface of said tibial component comprises two ridge portions 6b and a groove (6a) Fig. 10, (not shown), between them which extends longitudinally relative to the associated saddle shaping, the ridge portions being bridged across one end of said groove by an apertured web 6c. The femoral component may be of palstics material and the tibial component of metal, such as a chrome-cobalt alloy.
[GB1448818A]
Patent IE-781823-L (IE)
Title: Picture storage box and viewer device
IPC: B42F7/14
Filed: 1978-09-11
Abstract: A picture viewer for displaying, progressively, all of the pictures in a pile of pictures, including a housing with a viewing window, a pile support in the housing beneath the window, leaf springs urging the support toward the window, a spring-disabling control on the housing to disable such springs, a slider to be withdrawn and returned to the housing, a rotary transporter in the housing adjacent the window engaging the top picture in the pile, a driver on the slider to revolve the rotary transporter, and a separator to hold the pile in the housing while the one picture is stripped off and moved out upon withdrawal of the slider, the one picture being pushed back into the housing and under the pile by the slider upon its return, the rotary transporter being non-revolving or spaced from the pile during slider return.
[US4238898A]
Patent IE-40521-L (IE)
Title: Amusement device
IPC: A63F5/04
Filed: 1974-09-25
Abstract: 1478693 Fruit-machines SEEBURG CORP OF DELAWARE 23 Sept 1974 [27 Sept 1973] 41238/74 Heading G4V An amusement device has reels 8, 10 and 12 mounted on a shaft 42 by means of one-way clutches 50. Thus the reels are free to rotate after they have been driven by shaft 42 which has subsequently been stopped. A motor 60 drives a shaft 74 via chain 66. At one end of the shaft there is a cam wheel 76 having a follower 82 fixed to a link 84. The link is in contact with a stud 90 on wheel lever 92 which is biased clockwise by spring (96) Fig. 5 (not shown). Thus as motor 60 rotates shaft 70 clockwise link 84 is rotated clockwise and lever 92 is rotated anticlockwise against spring (96). When follower 82 reaches offset (80) on the cam the spring rotates wheel lever 92 rapidly which causes the reels 8, 10, 12 to rotate clockwise. The reels are attached to star plates 100, 102 and 104. Associated with the star plates are, respectively, stop levers 108, 110 and 112. These levers are pivotally mounted on shaft 114 and are biased by springs 118 so that rollers 126, 128 and 130 engage the star wheels. Control of such engagement is by cam followers 120, 122 and 124 and stop cams 132, 134 and 136 which are mounted on and rotated by shaft 70. Each cam has a high portion that engages the cam followers prior to rotation of the reels and releases the levers to stop the reels in the order, reel 8, reel 10, then reel 12. To determine a winning combination the star plates have holes 140 with pins 142 positioned in some of them. Associated with each star wheel is a feeler arm 140 mounted on shaft 144. At one end of the shaft a lever 148 has a cam follower 150 which can engage with feeler cam 152 mounted on shaft 70. The feeler arms are biased toward the star wheels by a spring engaging hooks 154. In operation the cam rotates the shaft 144 so that feelers 146 are moved clear of the star wheels, prior to rotation of the reels. After stopping of the reels a step in the cam allows shaft 144 to be rotated by the springs and the feelers move toward the star wheel until they engage a pin 142. Each feeler arm has a feeler wiper (234) Fig 2 (not shown) which contacts a strip (236) on each side of a printed circuit board (238) to provide an electrical circuit to determine if a winning combination has been obtained. Slots in the end walls 34, 36 enable the shaft assemblies to be put together externally of the device and then mounted in the device. Electronic circuitry allows up to 5 coins to be used successively to increase a winning score if a winning combination has been obtained by a user. A cam (240) Fig. 6 (not shown) controls the sequential operation of the machine and a variation of the time duration that the reels spin is controlled by a varistor cam (262).
[GB1478693A]
Patent IE-811995-L (IE)
Title: Security transfer apparatus
IPC: E05G7/00
Filed: 1981-08-31
Abstract: A security transfer unit includes a hollow box-structure that has open ends on opposite sides of a security barrier and is supported from side-frames with a clearance underneath. A rolling shutter encircles the box-structure to block access to either end to the chamber through openings in the unit casing. The shutter is driven to bring an aperture therein into register with the openings in turn so that access to the chamber can be gained through only one of them at a time. Drive is in one direction only and is interrupted with the shutter blocking both openings when the aperture is located in register with an aperture in the box-structure, so as to enable viewing of the contents of the transfer chamber through a window above.
[US4418628A]
Patent IE-792015-L (IE)
Title: Containers for vending machines
IPC: A47J31/44
Filed: 1979-10-22
Abstract: The invention relates to an ingredient container for a vending machine having a dispensing assembly wherein the container neck 11 carries a collar 12 incorporating a dispensing nozzle 23, interengagement means 25 and 18 being provided between the collar and the container neck and a valve guide member 30 being dimensioned to permit ingredients to pass to the dispensing nozzle 23 said valve guide member having a blind bore 33 therein and adapted to receive a valve member 34 movable between an open position and closed position and baffle means located generally at 38 based upwardly of the valve seat 24 for the valve 47 when the latter is in the closed position in order to control the ingredient flow to dispensing nozzle 23.
Patent IE-46001-L (IE)
Title: Process for the manufacture of 5-methyl isoxazole-4-¹carboxylic acid anilide derivatives
IPC: C07D261/18
Filed: 1977-12-02
Abstract: Preparation of novel 5-methylisoxazole-4-carboxanilides of the formula I <IMAGE> in which the individual symbols have the meaning given in Patent Claim 1, by reaction of a 5-methylisoxazole-4-carboxylic acid derivative with an appropriately substituted aniline. The compounds of the formula I are pharmacologically active. They exhibit potent anti-inflammatory and analgesic action.
[GB1572309A]
Patent IE-832455-L (IE)
Title: Aluminium hydroxide of mediandiameter 2-100 microns
IPC: C01F7/144
Filed: 1983-10-19
Abstract: PCT No. PCT/FR83/00209 Sec. 371 Date Jun. 13, 1984 Sec. 102(e) Date Jun. 13, 1984 PCT Filed Oct. 18, 1983 PCT Pub. No. WO84/01568 PCT Pub. Date Apr. 26, 1984.A process for the production of aluminum trihydroxide having controlled median diameter of 2 to 100 microns, with a unimodal distribution and minimum deviation, by decomposing a hot supersaturated sodium aluminate solution in the presence of seed aluminum trihydroxide, separating the resultant solid and liquid phases and recovering the solid phase constituted by precipitated aluminum trihydroxide. The process comprises grinding aluminum trihydroxide until the aluminum trihydroxide has a specific BET surface area of at least 1 m2/g, introducing the ground aluminum trihydroxide into a hot fraction of the supersaturated sodium aluminate solution to precipitate trihydroxide seed and then decomposing the remaining fraction of the supersaturated sodium alimuniate solution in the presence of the seed. This decomposition leads to the precipitation of aluminum trihydroxide having the required median diameter.
[US4582697A]
Patent IE-862748-L (IE)
Title: Biochemical retting of fibrous bast plants
IPC: D01C1/04
Filed: 1986-10-17
Abstract: The process for biochemical retting of phloem-fiber plants such as hemp, flax, ramie, jute, kenaf, etc. permits separation of the fibers of the bundle for subsequent utilization in the textile or paratextile industry.  The process comprises treating the fibrous plants with at least one SPS-ase enzyme and preferably a mixture of enzymes comprising  beta -glucanase, pectinase and SPS-ase.
Patent IE-883833-L (IE)
Title: Healing an external wound using platelet-derived growth¹factor
IPC: A61K38/00
Filed: 1988-12-21
Abstract: Healing an external wound or regenerating bone of a mammal by administering to the mammal a composition containing purified platelet-derived growth factor and purified transforming growth factor alpha.
[US4874746A]
Patent NO-790501-L (NO)
Title: Fremgangsmaate ved fremstilling av et limet papirprodukt
Inventor: SEROTA SAMUEL
IPC: D21J1/08
Filed: 1979-02-14
Abstract: Fremgangsmåte ved fremstilling av et limet papirprodukt.
Patent NO-792761-L (NO)
Inventor: LAMBOT JOSEPH HONORE
IPC: E21B3/02
Filed: 1979-08-24
Abstract: The invention relates to a drive mandrel for a drilling stem. The mandrel comprises a tubular element traversed by the drilling stem and having openings for the passage of jaws urged against the stem under the action of wedges. The wedges are spring biased against the jaws, and repelled from said jaws by hydraulic thrust. The wedges are mounted on an axially adjustable flange.
Patent NO-820364-L (NO)
Inventor: CORRIGAN FRANCIS RAYMOND
IPC: C25D5/54
Filed: 1982-02-08
Abstract: Boron rich cubic boron nitride suitable for use in electroplating processes (e.g. nickel plating) has been made by an acid leaching process. Boron rich aggregated cubic boron nitride grinding grits are leached in a mixture of nitric and sulfuric acids, the following conditions being typical; (a) volume ratio of 67% nitric acid to 98% sulfuric acid of 10:20; (b) temperature of 250 DEG  C; and (c) for a time of 1 hour. The process removes sufficient free surface boron to reduce the conductivity at the surface, resulting in an abrasive which does not overplate. FIG. 1 is a photomicrograph of a typical plated surface containing the improved CBN grinding grit of this invention, and FIG. 3 is an X-ray diffraction pattern characteristic of this new product.
Patent NO-820714-L (NO)
Inventor: AXMANN ARNOLD
IPC: B66C13/46
Filed: 1982-03-08
Abstract: An arrangement for controlling movement of the grab bucket of a grabbing crane used for loading and unloading bulk material into and from ships is disclosed. Collisions of the grab bucket with the ship's superstructure and the hatch edges are avoided according to the invention by approaching the hatch edges with the grab bucket open and displaying the actual values so obtained as bars representing the horizontal position and width of the hatch on a display. To avoid collisions, the grab bucket drives are switched off if any desired value, set manually or by a marking line computer, exceeds an actual value.
Patent NO-830599-L (NO)
Inventor: GASSER KURT
IPC: H03K17/62
Filed: 1983-02-21
Abstract: 1. A digital signal multiplexer for high data rates comprising AND-gates (U1 to U4), whose inputs (I1 to I4 ) are respectively supplied with a data signal (D1 to D4) and whose second inputs are supplied with phase-shifted clock pulses (T1 to T4 ) for switching the data signals (D1 to D4), and comprising an OR-gate (OR), whose inputs are supplied with the output signals of the AND-gates (U1 to U4), characterised in that between the outputs of the AND-gates (U1 to U4) and the inputs of the OR-gates (OR) is respectively arranged a pulse forming network having an ohmic resistor (R1 to R4 ) and an electrical conductor (Lk1 to Lk4 ), whose characteristic impedance corresponds to the resistance of the ohmic resistor (R1 to R4 ) in terms of value, that the input terminals (EL1, EL2) of the electrical conductor are connected to the ohmic resistor in series or in parallel, that the output terminals (A1, A2) of the electrical conductor are open or short-circuited, and that digital pulses of a predetermined duration are produced at the output (Ao ) of the pulse forming network by superimposition of an input pulse and a pulse reflected at the end of the electrical conductor, where the length of the electrical conductor, determines the duration of the digital pulses.
Patent NO-863545-L (NO)
Inventor: EK KURT LENNART
IPC: A23L7/157
Filed: 1986-09-04
Abstract: A process for the production of a crumb coating characterised in that a layer of liquid batter is formed on a heated surface, dried on the heated surface in such a way that it forms a coherent sheet, which sheet is detached from the heated surface, deep-fat fried, dried and finally milled to give crumbs of the desired particle size.
Patent NO-881734-L (NO)
Inventor: TURNER STEPHEN
IPC: C07D285/12
Filed: 1988-04-21
Abstract: Thiadiazole guanidines of formula 1 <CHEM>  wherein R is hydrogen or C1-4 alkyl and their non-toxic salts. Processes for their preparation and pharmaceutical compositions thereof. The compounds exhibit anti-convulsant activity and are indicated for use in the treatment of epilepsy.
Patent NO-892511-L (NO)
Inventor: HALLSTROEM STIG
IPC: F42B3/10
Filed: 1989-06-16
Abstract: An arrangement in explosive devices, e.g. shells, mines, bombs or the like, including a fuse (3), a main charge (1) and an auxiliary charge (4) which is disposed between the fuse and the main charge and effective in detonating the main charge. The main charge (1) is encapsulated in a safety casing and separated from the auxiliary charge (4) by different mechanical obstructions. In accordance with the invention, the auxiliary charge (4) comprises a charge having directed explosive action of the type which on being detonated produces a mass jet of high-order energy and high velocity. The auxiliary charge is oriented such that after penetrating an intermediate mechanical obstruction the jet will penetrate into the main charge, therewith detonating the main charge. To this end, the auxiliary charge (4) is spaced from the mechanical obstruction (11) by a distance sufficient to enable the jet to develop to the extent required, before meeting the obstruction.
Patent NO-894740-L (NO)
Inventor: DZIABO ANTHONY J
IPC: A61K47/02
Filed: 1989-11-28
Abstract: Stabilized chlorine dioxide is a preservative for ophthalmic formulations. The stabilized chlorine dioxide, when employed as a preservative or in the formulation of aqueous saline ophthalmic solutions is present in an amount of from about 0.0002 to about 0.02 weight/volume percent. The aqueous saline ophthalmic solutions, in addition to the stabilized chlorine dioxide and the water which functions as a vehicle for the solutions, contains from about 0.5 to about 0.9 weight/volume percent of an ophthalmically acceptable inorganic salt and an effective minor amount of a buffering agent to stabilize the ophthalmic solution with an acceptable physiological pH. A method for preserving aqueous saline ophthalmic solutions utilizing stabilized chlorine dioxide is also set forth.
Patent NO-901482-L (NO)
Inventor: SAKAI SHUZO
IPC: C12P19/18
Filed: 1990-04-02
Abstract: A method is provided for purifying 2-0-alpha-D-glucopyranosyl-L-ascorbic acid. The method comprises: providing a mixture containing 2-0-alpha-D-glucopyranosyl-L-ascorbic acid together with a water-soluble contaminant; and separating said mixture using a water-insoluble carrier in accordance with molecular weight or affinity into at least two fractions. The fractions comprise:   (i) a first fraction which is rich in 2-0-alpha-D-glucopyranosyl-L-ascorbic acid, and (ii) a second fraction which is rich in the contaminant. The first fraction is recovered.
Patent NO-902444-L (NO)
Inventor: CHRISTOPHERS ENNO
IPC: C12N15/81
Filed: 1990-06-01
Abstract: Polypeptides, in particular the polypeptide of formula I: Ala-Gln-Glu-Pro-Val-Lys-Gly-Pro-Val-Ser-Thr-Lys-Pro-Gly-Ser-Cys-Pro-Il e-Ile-Leu- Ile-Arg-Cys-Ala-Met-Leu-Asn-Pro-Pro-Asn-Arg-Cys-Leu-Lys-Asp-Thr-Asp-Cy s-Pro-Gly- Ile-Lys-Lys-Cys-Cys-Glu-Gly-Ser-Cys-Gly-Met-Ala-Cys-Phe-Val-Pro-Gln and analogues thereof which possess inhibitory activity against human leukocyte elastase. The polypeptides may be obtained by expression using plasmidic expression systems in hosts such as E. Coli and yeast, the polypeptide of formula I being also obtainable from psoriatic plaques.
Patent NO-921944-L (NO)
Title: Benzofuran-derivater
Inventor: ROSS BARRY CLIVE
IPC: C07D405/14
Filed: 1992-05-15
Abstract: Ifølge oppfinnelsen tilveiebringes en forbindelse med den generelle formel (I): Het-CH, eller et fysiologisk godtagbart salt, solvat eller metabolsk labil ester derav, hvor R1 er hydrogen, halogen, alkyl, alkenyl, fluor-alkyl, alkoksy, -CHO, -COOH eller COR Ar betyr gruppen 2 R2 er alkyl, alkenyl, alkoksy eller -NR13N14; R3 er -COOH, -NHSO.CF. eller en C-bundet tetrazolyl-gruppe; R4 og R5 er hver hydrogen, halogen eller alkyl, Het betyr gruppen R er hydrogen eller alkyl, alkenyl, alkyltio, alkoksy, cyklo- alkyl eller cykloalkylalkyl; R7 er hydrogen, halogen, cyano, nitro, alkyl, alkenyl, fluor- alkyl, -(CH_% "9 eller cykloalkyl-alkyl; R8 er hydrogen, halogen, cyano, nitro, alkyl, alkenyl, fluor- alkyl, -(CH_) R9, -(CH,) COR10 eller -(CH2) NR11COR12, og R9, R10, R11, R , R13 og R1 er en rekke grupper og substitu- , -(CH2) '¿ -(CH2)r,NRllcoRl2' cykloalkyl enter; med det forbehold at når R er hydrogen eller alkyl, alkenyl eller alkyltio, er R7 cykloalkyl eller cykloalkyl- alkyl. forbindelsene kan anvendes for behandling eller profy- lakse av hypertensjon og sykdommer forbundet med kognitive forstyrrelser.
Patent NO-922148-L (NO)
IPC: C07F5/00
Filed: 1992-05-29
Abstract: Gallium(III)komplekser med den generelle formel I hvor X = 0_CR2, halogen, NO eller -OA, R1 = H, alkyl, alkyl, alkoksy eller R5 og R6 = H eller alkyl og n = O, l alkoksy, halogen, N0_ eller amino, R aryl, hver av R3, R4 eller 2; eller når n = O og R og R begge = H, danner R og R5 sammen tetrametylen, og A er identisk med det galliumkompleks som X er knyttet ttl, absorberes godt ved peroral tilførsel og er indisert som medikamenter ved hyperkalsemi og cancerkjemoterapi.
Patent NO-922761-L (NO)
Title: Fremgangsmaate til gradering av materiale, samt tilhoerendeapparat
Inventor: LERNER MOISEI MIKHAILOVICH
IPC: B65G47/64
Filed: 1992-07-13
Abstract: En fremgangsmåte for sortering av gjenstander, samt apparat for utøvelse av fremgangsmåten. Apparatet omfatter en enhet (1) for enkeltvis mating av gjenstander (2), en transporter (3) med bæreelementer (4), en innretning (5) for føring av gjenstandene til bestemmelsessteder, en innretning (6) for å returnere bæreelementene til utgangsstillingen, et automatisk styresystem (7) med en anordning (8) for måling av fortløpende verdier av sorteringskarakteristikkene, og aktuatorer (9), en enhet (10) for å bestemme antallet bæreelementer hvorpå gjenstanden som skal håndteres legges, og en enhet (11) for å registrere bevegelsen til bæreelementene. Anordningen (8) for måling av de fortløpende verdier av sorteringskarakteristikkene er tilknyttet enheten (10) for bestemmelse av antallet bæreelementer. Apparatet har mulighet for ulike utførelser av transportøren, dvs. lineære, langsgående, og horisontale, roterende sløyfetransportører. Bæreelementene kan monteres horisontalt på en tran-sportør, på to parallelle transportører, eller ved en vinkel til hverandre for slik å danne en U-formet kanal som er tilpasset for opptak av gjenstanden som skal håndteres. Driften av apparatet utføres med det automatiske styresystem ved bruk av en algoritme i samsvar med brukerens behov eller krav.
Patent NO-923681-L (NO)
Title: Fremgangsmaate for fremstilling og anvendelser av hoeytemperatur-broennsementsammensetninger
Inventor: TOTTEN PATTY L
IPC: C04B24/26
Filed: 1992-09-22
Abstract: Forbedrede størkningsretarderte sementsammensetninger og fremgangsmåter for å anvende slike sammensetninger, som i det vesentlige er lkke-fortynnende ved høye temperaturer og som kan inkludere ferskvann eller saltvann. Sammensetningene omfatter hydraulisk sement, tilstrekkelig vann til å danne en pumpbar oppslemming, en størkningsretarderer og et forsinket viskosifiser-ingsmiddel som gir viskositet ved heye temperaturer og er omfattet av en behandlet depolymerisert galakto-mannangummi.