baber/WOPTO huggingface dataset:
Patent ES-8801838-A1 (ES)
Title: Peptides.
IPC: A61P43/00
Filed: 1985-10-18
Abstract: New peptides of the formula I X-Z-NH-CHR-CHOH-CH2-CO-NH-CHR1-CH2-NH-CHY-CnH2n-R2 I in which X is H, R3-O-CH2-CO-, R3-O-CO-, R3-CH2-O-CO- or R3-CmH2m-CO-, Z is 1 to 4 aminoacid residues which are bonded together in the manner of peptides and are selected from the group comprising Abu, Ala, Arg, Asn, Dab, Gln, Gly, His, Ile, Leu, Lys, Met, NLeu, Orn, Phe, Pro, Trp, Tyr and Val, is A, Ar-alkyl (in which the group -alkyl contains 1-4 C atoms) or cycloalkyl-alkyl having 4-11 C atoms, R1 is H or A, Y is H, A, -CpH2p-OR4, -CpH2p-NHR4, -COOR4, -CONHR4 or -CONA2, R2 is A, cycloalkyl having 3-7 C atoms, Ar, pyridyl, indolyl, imidazolyl, piperidyl, N-benzylpiperidyl or piperazinyl, R3 is A, cycloalkyl having 3-7 C atoms or Ar, R4 is H, A or cycloalkyl having 3-7 C atoms, A is alkyl having 1-6 C atoms, Ar is phenyl which is unsubstituted or substituted once or several times by A, AO, F, Cl, Br, I, CF3 and/or NH2, or is unsubstituted naphthyl, and m, n and p each are 0, 1, 2, 3, 4 or 5, and their salts inhibit the activity of the renin in human plasma.
Patent ES-8702736-A1 (ES)
Title: Remote control circuit breaker having a retractable switch contact
IPC: H01H3/02
Filed: 1986-01-22
Abstract: A circuit breaker is provided with at least one switching arrangement having a mobile contact and a retractable contact, this latter being supported by a pivoting lever a tripping mechanism for causing the rapid opening of the mobile contact, an electromagnetic actuator having an element movable in translation under the effect of a control signal applied to the actuator and a mechanical coupling for transmitting the movement of the mobile element to the retractable contact, wherein the mechanical coupling is rigid and moves in translation according to a translation plane parallel to the movement of the mobile element and it is coupled to said pivoting lever at a point offset with respect to the plane of translation.
Patent ES-8706834-A1 (ES)
Title: Method for producing L-sorbose.
IPC: C12P19/02
Filed: 1986-04-21
Abstract: In a method for producing L-sorbose by microbial oxidation of D-sorbitol, a competent microorganism is cultivated in a medium in which the concentration of dissolved oxygen is controlled in the range of about 1 to about 4 ppm throughout the growth phase of said microorganism. Thus, L-sorbose can be produced in much greater yield, compared with known methods.
Patent ES-8800136-A1 (ES)
Title: Process for the preparation of pyrrolidone derivatives.
IPC: C07D207/273
Filed: 1986-05-16
Abstract: A process for preparing compounds (1) < IMAGE > (1) where Y is NR1R2 or OR, R1 and R2 are hydrogen or C1-3 alkyl, and R is C1-3 alkyl, which comprises protecting the hydroxy group of a compound (2) < IMAGE > (2) cyclising the product under basic conditions and removing the protecting group.
Patent ES-8801913-A1 (ES)
Title: 5-Amino-1-pyridyl-pyrazoles.
IPC: C07D401/04
Filed: 1987-05-14
Abstract: Herbicidally active novel 5-amino-1-pyridyl-pyrazoles of the formula < IMAGE > in which R1 represents hydrogen or represents alkyl with 1 to 12 carbon atoms, R2 represents hydrogen, nitro, nitroso or halogen, or represents a radical < IMAGE > wherein R5 represents hydrogen, hydroxyl, alkyl, alkenyl, alkinyl, halogenoalkyl, alkoxyalkyl or alkylthioalkyl, or represents optionally substituted cycloalkyl, or represents optionally substituted aryl, or represents alkoxy or alkylthio, or represents optionally substituted aryloxy, or represents optionally substituted arylthio, or represents alkylamino or dialkylamino, or represents optionally substituted arylamino, R3 represents hydrogen, or represents a radical < IMAGE > or represents a radical -S(O)n-R7, R4 represents hydrogen, or represents alkyl, or represents a radical < IMAGE > or represents a radical -S(O)n-R7, and, in the case where R3 represents an -SO2-R7 radical, also represents an inorganic or organic cation bonded in salt form, and R6 represents hydrogen, alkyl, alkenyl, alkinyl, halogenoalkyl, alkoxyalkyl or alkylthioalkyl, or represents optionally substituted cycloalkyl, or represents optionally substituted aryl, or represents alkoxy or alkylthio, or represents optionally substituted aryloxy, or represents optionally substituted arylthio, or represents alkylamino or dialkylamino, or represents optionally substituted arylamino, X represents oxygen or sulphur, n represents the number 0, 1 or 2, R7 represents alkyl, halogenoalkyl or optionally substituted aryl and Py represents substituted C-linked pyridyl. Some of the intermediates wherein the 5-position of the pyrazole carries a halogen atom are also new.
Patent ES-8801315-A1 (ES)
Title: Novel THF compositions.
IPC: C07K5/08
Filed: 1987-09-16
Abstract: Novel peptide materials having thymic humoral activity are disclosed having the respective amino acid sequences of: Leu-Glu-Asp-Gly-Pro-Lys-Phe-Leu His-Pro-Leu-Pro-Asp-Leu-Tyr and Phe-Val-Leu These novel peptides can be isolated from natural thymus glands or can be prepared synthetically.
Patent IE-902978-A1 (IE)
Title: 5-methyl-isoxazole-4-carboxylic acid anilides and¹2-hydroxyethylidene-cyano acetic acid anilides for the¹treatment of ocular diseases
IPC: A61K31/42
Filed: 1990-08-17
Abstract: The use of 5-methyl-isoxazole-4-carboxylic acid anilides and 2-hydroxyethylidene-cyano acetic acid anilides for treating ocular diseases with immune etiology is disclosed.
Patent IE-903169-A1 (IE)
Title: Inhibition of lymphocyte adherence to vascular endothelium¹utilizing a novel extracellular matrix receptor-ligand¹interaction
IPC: A61P37/00
Filed: 1990-08-31
Abstract: The present invention relates to a method for inhibiting the adhesion of one cell to another comprising interfering with the interaction between the extracellular matrix receptor and its ligand. The invention is based upon the discovery that the  alpha 4 beta 1 extracellular matrix receptor promotes adhesion of lymphocytes to endothelial cells via attachment to a defined peptide sequence. Prior to the present invention, the ligand of the  alpha 4 beta 1 receptor had not been identified, nor had the function of the  alpha 4 beta 1 receptor in lymphocyte attachment been known. By preventing the interaction between the  alpha 4 beta 1 receptor and its ligands using antibodies or defined peptide sequences, the present invention enables, for the first time, specific intervention in the migration of lymphocytes through the vascular endothelium and into tissues. The present invention, therefore, has particular clinical utility in suppression of the immune response, in various specific embodiments of the invention, the adherence of lymphocytes to endothelium may be inhibited systemically, or may, alternatively, be localized to particular tissues or circumscribed areas. Accordingly, the present invention provides for treatment of diseases involving autoimmune responses as well as other chronic or relapsing activations of the immune system, including allergy, asthma, and chronic inflammatory skin conditions.
Patent IE-903380-A1 (IE)
Title: Nmda antagonists
Inventor: WHITTEN JEFFREY PAUL
IPC: A61K31/66
Filed: 1990-09-18
Abstract: The present invention is directed to a new class of beta-­ketone, beta oxime and beta hydrazine phosphonate NMDA antagonists.
Patent IE-903686-A1 (IE)
Title: Polyol polyester synthesis
Inventor: HOUSTON ROBERT
IPC: C07B63/00
Filed: 1990-10-15
Abstract: Polyol polyesters are purified by a process comprising bleaching with a specific silica gel and/or treating with oxygen followed by heat treatment and removal of volatile products by steam deodorization. Any steam deodorization is accomplished at reduced temperatures or in admixture with triglycerides to minimize thermal degradation of the polyol polyesters.
Patent IE-920304-A1 (IE)
Title: Improvements relating to smoking articles
Inventor: LUKE JOHN ANTHONY
IPC: A24D1/00
Filed: 1992-01-30
Abstract: This invention provides a smoking article (1) having reduced sidestream smoke in the inter-puff period. A smoking article (1) according to the invention may comprise segments of a high level of tobacco-containing material (5) interconnected by segments of low level of tobacco-containing material(6) which are capable of maintaining smoulder in the inter-puff period and re-igniting the segments of a high level of tobacco-containing material(5) in the puff period. Alternatively, a smoking article according to another aspect of the invention may comprise a lengthwise, axially extending, tobacco-containing fuse portion (46) which sustains smoulder in the inter-puff period when surrounding tobacco material (45) is substantially extinguished and which re-ignites the extinguished material on puffing of the smoking article(1). <IMAGE>
Patent IE-920324-A1 (IE)
Title: Paper article dispenser
Inventor: CORNELL ROBERT G
IPC: B42D5/00
Filed: 1992-02-11
Abstract: This invention relates to dispensers for stacks of paper articles. The problem with such dispensers is the need for additional space for the biasing spring which biases the stack of articles toward the dispensing opening. The invention eliminates the need for additional space to accommodate the biasing spring. A paper article dispenser (10) including a housing (12, 14) for storing a stack (16) of paper articles (18) therein and a mechanism (such as a leaf spring) (20) for urging the stack (16) toward an opening (22) in the housing to facilitate removal of one of the paper articles (18) through the opening (22). The spring (20) is configured and positioned to lie substantially flat within the housing when the spring is fully compressed. In another aspect, the base of the housing is constructed with integral, resilient members (102, 104) that bias the stack toward the opening.
Patent IE-921291-A1 (IE)
Title: Improvement of the yield when disulfide-bonded proteins are secreted
Inventor: GLOCKSHUBER RUDOLF
IPC: C12P21/04
Filed: 1992-04-22
Abstract: The invention relates to a method for enhancing the development of the natural protein conformation on secretion of proteins with a disulphide bridge by a prokaryotic host organism which contains a recombinant DNA which codes for the secreted protein, in which the host organism is cultured in a suitable nutrient medium under suitable conditions for the expression of the recombinant DNA, which is characterised in that a nutrient medium containing 0.1 to 20 mmol/l of one or more thiol reagents is used.
Patent IE-921559-A1 (IE)
Title: Composition and method of treating depigmentation disorders
Inventor: SCHALLREUTER KARIN UTA
IPC: A61K33/32
Filed: 1992-07-01
Abstract: PCT No. PCT/GB92/00878 Sec. 371 Date Nov. 15, 1993 Sec. 102(e) Date Nov. 15, 1993 PCT Filed May 15, 1992 PCT Pub. No. WO92/20354 PCT Pub. Date Nov. 26, 1992.Vitiligo and other tyrosinase-positive depigmentation disorders are treated by topical application of a pseudocatalase and subsequent exposure to a sub-minimal erythema dose of UVB light. After a course of treatment, pigmentation of the affected areas can be maintained by treatment with the pseudocatalases without UVB light treatment. The preferred pseudocatalases are transition metal co-ordination complexes, especially manganese (II) bicarbonate.
Patent IE-930983-A1 (IE)
Title: Scraper apparatus for cylindrical tanks
Inventor: DAVIDSON ERIC SAMUEL
IPC: B01D21/04
Filed: 1993-12-20
Abstract: A cylindrical tank (10) has a scraper apparatus for removal fo deposit from its bottom. The bottom of the tank (10) has an outer peripheral path (14), an inwardly sloping floor (16) and a central sump (18). The apparatus comprises two pairs of radial scraper arms (20) each having a series of depending blades (22) to sweep across and against said floor(16) to direct any deposit thereon into the sump (18) for removal therefrom. Each arm (20) is supported at or adjacent to its inner end centrally of the tank (10) and has a low friction rotatable wheel (24) at its outer end tracking the path (14). The tank (10) has inlet and outlet facilities. Means are provided to move the arms (20) around the tank (10).
Patent WO-9610942-A1 (WO)
Title: Faitout-cuisiniere polyvalent
Inventor: STEPHANOU A M
IPC: A47J37/00
Filed: 1995-10-01
Abstract: Faitout-cuisinière polyvalent constitué d'un récipient chauffant (1), d'un récipient de cuisson (2) apte à s'emboîter dans le récipient chauffant, et d'accessoires permettant d'effectuer différentes opérations de cuisine. Ce dispositif peut servir de cuisinière, de poêle à frire, de gril, de 'braai' (gril typique d'Afrique du Sud), de wok chinois, de pocheuse, de marmite à vapeur, de réchaud pour fondue, de friteuse ou de four à pain ou analogue, et, avec quelques petites modifications, il pourra même servir d'autocuiseur. Le récipient chauffant (1) contient un organe chauffant tel qu'un corps de chauffe électrique ou un brûleur à gaz. Des parties saillantes sont formées par emboutissage dans sa paroi latérale légèrement au-dessus du corps chauffant, et elles permettent l'aération et servent de support. Les accessoires principaux sont un couvercle, une grille, un panier à frire, un wok chinois, un récipient dont le fond est percé de grandes ouvertures dans lesquelles s'emboîtent de petits éléments cupuliformes, et un disque de cuisson à la vapeur muni de petits trous et d'une cloison. Pour faire une grillade, on place la grille au fond du récipient de cuisson, on retourne le récipient chauffant et on le place sur le récipient de cuisson. Sinon, on introduit le récipient de cuisson dans le récipient chauffant de sorte qu'il repose sur les parties saillantes, et, le cas échéant, on place le couvercle sur le récipient de cuisson. Pour pocher des oeufs, on place dans le récipient de cuisson le récipient muni de grandes ouvertures, et on place les petits éléments cupuliformes dans lesdites ouvertures. Pour la cuisson à la vapeur, on place le disque muni de petits trous au fond du récipient muni desdites grandes ouvertures.
Patent AT-515853-A1 (AT)
Title: Leuchtrahmen
Inventor: MÜLLER RAIMUND
IPC: G09F13/04
Filed: 2015-05-21
Abstract: Die Erfindung geht aus von einem Leuchtrahmen (10) zur Aufnahme eines Bilds, mit zumindest einer LED (12) zur Beleuchtung des Bilds, mit zumindest einer Außenscheibe (14), und mit zumindest einer Streuscheibe (20), die eine Schmalseite (22), die zur Einkopplung von Licht der LED (12) vorgesehen ist, und eine Oberfläche (24), die zur Hinterleuchtung des Bilds vorgesehen ist, aufweist. Es wird vorgeschlagen, dass die Schmalseite (22) der Streuscheibe (20) konkav gekrümmt ausgeführt ist und dass die zumindest eine LED (12) mit einem Neigungswinkel (32) gegenüber der Schmalseite (22) angeordnet ist. Die Erfindung betrifft ferner ein Verfahren zur Herstellung einer Lichtauskoppelstruktur (46) in einem erfindungsgemäßen Leuchtrahmen (10), bei dem zur Herstellung der Lichtauskoppelstruktur (46) Linien (48) in die Streuscheibe (20) eingeritzt werden.
Patent WO-8707220-A1 (WO)
Title: Handstamp with several selectable printing plates
Inventor: SKOPEK KARL
IPC: B41K1/08
Filed: 1987-02-13
Abstract: Handstamp with several selectable printing plates (2) which are applied to a rotatable polygonal cylinder (1), which, when turned, brings the desired printing plate (2) into the position of use; the stamp includes a display with indications of the content of the printing plate, said display being provided with a cylinder (3) carrying this information on its periphery, and being linked with the printing-plate carrying cylinder via a gear system (15, 16, 17). The information-carrying cylinder (3) of the display is arranged in the housing (5) of the stamp with the axle (35) running parallel to the axle (34) of the cylinder (1) carrying the printing plates under or above the latter. Preferably the cylinder (3) of the display together with the printing plate carrying cylinder (1) are accommodated in a slide (4) which can be moved in the housing (5) of the stamp.
Patent WO-0108604-A1 (WO)
Title: Compositions biomedicales hydrophiles
Inventor: CLAYTON ANTHONY BRIAN
IPC: A61L27/16
Filed: 2000-08-02
Abstract: L'invention concerne un macromonomère hydrophile insaturé en éthylène, élaboré en polymérisation par addition de monomères pouvant être soumis à ce type de polymérisation. Lesdits monomères englobent des monomères à groupes fonctionnels hydroxyle ou amino, dont certains peuvent être soumis ultérieurement à une réaction visant à établir une insaturation (méth)acryle éthylénique. Il est possible d'utiliser les macromonomères considérés pour former des lentilles intraoculaires in situ, par polymérisation.
Patent WO-0177804-A1 (WO)
Title: Appareil permettant de controler un equipement de jeu electronique
Inventor: YII PATRICK ANTHONY
IPC: A63F13/20
Filed: 2001-04-05
Abstract: L'invention concerne un appareil permettant de contrôler un équipement de jeu électronique, cet appareil possédant une base et un siège. Le siège est monté de manière à pouvoir pivoter selon un axe vertical par rapport à la base. Un appareil de détection de la position du siège, qui sert d'interface avec l'installation de jeu électronique, permet de détecter la position en rotation du siège et des moyens qui y sont connectés de manière fonctionnelle et qui se déplacent simultanément au siège. Ces moyens permettent par ailleurs de monter plusieurs moyens de contrôle accessibles pour l'opérateur servant d'interface avec l'installation de jeu électronique. Selon l'un des modes de réalisation de la présente invention, on trouve également un moyen de réglage permettant aux opérateurs de différentes tailles de s'asseoir sur ledit siège. Dans un mode de réalisation différent, un seul et même dispositif permet de régler la taille de l'opérateur et de faire pivoter ledit siège.
Patent WO-03088889-A1 (WO)
Title: Massage lymphatique auto-administre
Inventor: PILLER NEIL
IPC: A61H23/02
Filed: 2003-04-17
Abstract: La présente invention a trait à un ensemble de compresse comportant un boîtier de moteur d'entraînement (11) relié à un bâti vibratoire (12) situé au sein d'un ensemble de coussins (13) caché. Un moteur à courant continu (14) entraîne l'arbre (15) qui porte un poids (16) de sorte que l'arbre est déséquilibré. L'arbre se déplace dans des paliers autocentrés et est entraîné à une fréquence thérapeutique fixe de 47 hertz pour imiter un massage de drainage lymphatique manuel.
Patent WO-03089762-A1 (WO)
Title: Haveuse a disque oscillant a paliers de regulation de vitesse
Inventor: SUGDEN DAVID BURNET
IPC: E21D9/10
Filed: 2003-04-22
Abstract: L'invention concerne une haveuse à disque oscillant (10), comprenant un disque de coupe (602) et un mécanisme d'entraînement. Ce mécanisme d'entraînement comprend un arbre d'entraînement (612), conçu pour entraîner le disque de coupe dans un mouvement d'oscillation excentrique, et un palier radial (609) installé de manière à permettre une rotation entre l'arbre d'entraînement et le disque de coupe. Cette haveuse comprend également un palier axial hydrostatique (700), installé de façon à réagir à des forces axiales tout en adaptant la rotation induite du disque de coupe, une fois mis en contact avec la roche pour la couper, et à freiner la rotation afin de limiter, ainsi, la vitesse de rotation du disque de coupe en oscillation libre. Un palier à eau sous pression (605) induit une charge axiale prédéterminée dans le palier hydrostatique, de sorte qu'un jeu fonctionnel maximal prédéterminé dans ce palier hydrostatique est maintenu.
Patent WO-2004003315-A1 (WO)
Title: Element de construction universel d'angle
Inventor: MUCCI ANTONIO
IPC: E04F21/04
Filed: 2003-06-24
Abstract: Cette invention se rapporte à un élément de construction qui comprend une paire de côtés plats allongés parallèles espacés (10) moulés à partir d'un enduit de ciment léger renforcé par fibres et joints le long de bords allongés adjacents (13) par une toile de verre électrique (15). La toile traverse les côtés et forme une aile (16) s'étendant à partir des bords allongés opposés (13) qui sont biseautés. Cet élément de construction est fixé à la surface d'un mur au niveau d'un angle interne ou externe par clouage ou par collage de ses côtés allongés aux surfaces du mur sur les côtés correspondants de l'angle. La surface du mur peut ensuite être recouverte d'un revêtement appliqué affleurant la face externe des côtés (10).
Patent WO-2004016284-A1 (WO)
Title: Methode d'immunomodulation
Inventor: KATO MASATO
IPC: C07K16/28
Filed: 2003-08-15
Abstract: L'invention concerne, de façon générale, une méthode servant à moduler l'activité de cellules du système immunitaire, y compris des cellules répondantes et stimulantes et des agents utiles. Elle concerne, plus particulièrement, une méthode servant à prévenir ou à réguler en négatif une ou plusieurs activités fonctionnelles de ces cellules stimulantes et répondantes telles que, respectivement, des cellules présentant des antigènes et des lymphocytes entre autres. Elle concerne, de plus, des anticorps entrant en interaction spécifique avec des déterminants antigéniques présents sur la surface des cellules présentant des antigènes et des lymphocytes, ce qui permet d'obtenir un appauvrissement, une régulation négative ou la destruction de cellules présentant des antigènes et de lymphocytes ciblés in vivo ou in vitro. Elle concerne également une méthode servant à moduler une réponse immune chez un sujet et, en particulier, à réguler en négatif l'immunoactivité d'un greffon halogène immuno-compétent et/ou la réponse immune du récepteur d'une transplantation d'organe solide. Cette capacité de modulation de l'immunoactivité de cellules stimulantes et répondantes peut être utile, entre autres, dans une variété de traitement immuno-thérapeutiques et immuno-prophylactiques tirant des avantages de la suppression immune.
Patent AU-2001231947-A1 (AU)
Title: Method for preparing plant extracts, plant extracts obtained by said method and uses thereof
Inventor: JEAN DANIEL
IPC: A61K36/28
Filed: 2001-01-31
Abstract: The invention concerns a method for preparing a plant extract, which consists in: freezing the whole plant or its active parts at a temperature </= -10  DEG C; grinding said plant or its active parts at a temperature of said plants or active parts thereof </= -20  DEG C; at least an operation which consists in expressing juice from the ground material at a ground material temperature ranging between about  5 and 0  DEG C; at least leaching the residue of said expression with a water miscible organic solvent at a temperature of said residue ranging between about 0 and 25  DEG C; and mixing into one single extract the juice and the extractives derived from leaching, after optionally concentrating said extractives. The invention also concerns a plant extract obtainable by said method and the uses of said extract as medicine, cosmetic product or food supplement or for preparing formulations for medicinal, cosmetic or food purposes.
Patent AU-2001240470-A1 (AU)
Title: Methods and systems for navigating under water
Inventor: LARSEN MIKAEL BLIKSTED
IPC: G01S5/18
Filed: 2001-03-02
Abstract: In a method for determining absolute position under water of a submersible vessel ( 1 ) having a dead reckoning navigation system and receiving acoustic signals from a reference station ( 19 ), signals are received from one reference station in several positions ( 15-18 ) of the vessel. Estimated absolute positions of the vessel are calculated using range data and relative position data. Range rate data derived from the signals are preferably utilised. In a method for scanning an underwater survey area, the absolute position of a vessel ( 1 ) is intermittently being determined according to said method. The reference station may be placed at a fixed absolute position ( 19 ), or on the surface of the water, preferably in a buoy or a vessel. A system for determining the absolute position under water of a vessel comprises: acoustic communication means in a reference station and on board the vessel; a dead reckoning navigation system on board the vessel; and computing means.