baber/WOPTO huggingface dataset:
Patent TW-202328454-A (TW)
Title: Optimized cyp4v2 gene and use thereof
Inventor: CAO QING
IPC: C12N15/63
Filed: 2022-12-22
Abstract: The disclosure relates to an optimized CYP4V2 gene and the use thereof. The gene relates to a polynucleotide encoding a CYP4V2 protein, which contains nucleotide sequences that are 90% or more identical to those shown in SEQ ID NO 5, SEQ ID NO 6, SEQ ID NO 7, SEQ ID NO 8, or SEQ ID NO 9. The disclosure also relates to an expression vector containing the gene that achieves efficient, persistent and stable expression in the retinal pigment epithelium of the eye to effectively reduce the dose and potential side effects of gene therapy reagents in treating Bietti crystalline corneorteinal dystrophy (BCD) and to improve the therapeutic effect.
Patent TW-202331107-A (TW)
Inventor: KIM CHANG-KYUM
IPC: F04D25/08
Filed: 2020-11-27
Abstract: An air conditioner of the present disclosure includes a base case configured to include a suction port through which air is sucked and accommodate a filter therein, a tower case configured to be disposed above the base case and to include a discharge port through which the air sucked from the suction port is discharged, and a heater configured to be disposed inside the tower case to heat the air.
Patent UA-38245-A (UA)
Title: Siphon plug
Filed: 2000-06-09
Abstract: A siphon plug has a form of cap with screw thread on internal cylindrical surface and seal on the internal surface of the bottom. Plug has a seal over internal cylindrical surface at the end of the thread and has an opening directed towards external surface of the bottom and connected by channel with internal threaded surface. The invented device can be used at pouring of gassed beverages for drinking.
Patent UA-39487-A (UA)
Title: remover of ROLLs
Filed: 2000-09-12
Abstract: A remover of coils contains a stationary frame with located on it platform, cradle, drives of vertical and horizontal displacement and guides, and also tightening roller with the drive. The cradle is installed with possibility of horizontal displacement on the guides located on the platform, which is installed with possibility of vertical displacement. Drives of horizontal displacement of cradle, vertical displacement of platforms and pressing of roller are installed in steady-state and are connected with the last lever systems. The invention relates to the branch of working metal by pressure, rolling equipment and it can be used for removing the coils from the drum of the winder of bar mill.
Patent UA-40430-A (UA)
Title: Спосіб лікування гастродуоденальних захворювань у дітей, пов'язаних із підвищеною секреторною функцією шлунка
Inventor: NECHYTAILO YURII MYKOLAIOVYCH
Filed: 2001-01-25
Abstract: Реферат Спосіб лікування гастродуоденальних захворювань у дітей, пов`язаних із підвищеною секреторною функцією шлунка шляхом призначення лікарського препарату-блокатора Н2-рецепторів гістаміну. Препарат приймають у перорально ізотонічному сольовому розчині. Одночасно впливають гальванічним струмом на енігастральну ділянку черевної стінки.
Patent UA-50637-A (UA)
Title: Automatic laundry washer of drum type
Inventor: MYKHAILOV VOLODYMYR IVANOVYCH
Filed: 2002-03-15
Abstract: Automatic laundry washer of drum type has a drum with rows of perforated apertures formed at its surface. Perforated apertures are arranged at the side and/or end surfaces of the drum, at that the apertures are made as intakes, in the shape of semi-cones, or of any other figure, inscribed with respect to that semi-cone; at that the intakes of each row are placed in opposite direction with respect to the intakes of the other row.
Patent UA-60136-A (UA)
Title: Method for preventing caries
Inventor: POMOINYTSKYI VIKTOR HRYHOROVYCH
Filed: 2003-02-04
Abstract: The method for preventing the caries comprises rinsing the oral cavity immediately after the consumption of the sweets. 0.25-0.40% solution of acarbose as the inhibitor of glucosidases is used for this purpose (5-10 ml for 30-60 seconds).
Patent DO-P2023000110-A (DO)
Title: MATERIAL TERAPÉUTICO CON BAJO pH Y DE BAJA TOXICIDAD ACTIVA CONTRA AL MENOS UN PATÓGENO PARA EL TRATAMIENTO DE PACIENTES CON ENFERMEDADES RESPIRATORIAS
Inventor: LAWRENCE CARLSON
IPC: A61K33/04
Filed: 2023-06-02
Abstract: Método y composición para el tratamiento o la prevención de enfermedades respiratorias. El método incluye la administración al menos una dosis de una forma farmacéutica líquida con un pH inferior a 3,0, en contacto con al menos una región del tracto respiratorio presente en el paciente que lo necesite. Las enfermedades respiratorias que pueden ser tratadas incluyen COVID-19.
Patent EC-SP11011371-A (EC)
Title: Inhibidor de la map cinasa p38
Inventor: ITO KASUHIRO
IPC: A61K31/415
Filed: 2011-10-03
Abstract: La presente invención se refiere a un compuesto de la Fórmula (I):o una sal farmacéuticamente aceptable del mismo, incluyendo todos los estereoisómeros y tautómeros, que es un inhibidor de las enzimas de proteína cinasa activadas por mitógeno p38 (en adelante se mencionan como inhibidores de la MAP cinasa p38), en particular sus subtipos de alfa y gamma cinasa, y su uso en terapia, incluyendo en combinaciones farmacéuticas, especialmente en el tratamiento de enfermedades inflamatorias, incluyendo las enfermedades inflamatorias del pulmón, como la EPOC.
Patent GB-189700449-A (GB)
Title: Improvements in connection with Projecting Lanterns.
Inventor: HUGHES WILLIAM CHARLES
Filed: 1897-01-07
Granted: 1897-02-13
Abstract: 449. Hughes, W. C. Jan. 7. Magic-lanterns.-In order that the light may be concentrated directly upon the centre of the picture (or in kinematographs upon the travelling ribbonlike film) K, an improved condenser of small diameter and short focus is employed, consisting preferably of a double convex lens and meniscus J<1>.
Patent GB-189703286-A (GB)
Title: An Improved Automatic Apparatus for Playing a Game of Skill, with Coinfreed and Coin Operated Mechanism.
Inventor: GALLEY FREDERICK GEORGE
Filed: 1897-02-08
Granted: 1898-01-08
Abstract: 3286. Galley, F. G., and Robey, P. W. Feb. 8. Game of skill, apparatus for.-The coin rolls down an incline E, and either falls off at the side or rolls into one of four mouths a, a', a<11>, a<111>, where either a shoot which connects the outer pair of mouths conveys it to a goods' delivery mechanism or a shoot which connects the inner pair of mouths returns it to the patron. Skill is required to set the coin at the entry slot so that it will roll into the delivery mechanism. Fraud, preventing.-To prevent the introduction of guides, the entrance slot is guarded by a pocket, but the coin can be manipulated through side slots. If a coin falls flat on the incline, it slides to a trap H and falls therefrom.
Patent GB-189710470-A (GB)
Title: Improvements in Cleaning Trunks for Use in connection with Cotton-openers.
Inventor: POTTER JAMES CHARLES
Filed: 1897-04-27
Granted: 1897-06-12
Abstract: 10,470. Potter, J. C. April 27. Openers; feeding-trunks.-The object is to facilitate the discharge of dirt, dust, &c. from the chambers or pockets 9 below the grating of the trunk. The chambers are formed by the transverse partitions 8, much deeper at one end than the other as shown, and are closed by doors 10. Each door is hinged at one side of the trunk to hanging brackets 11, and at the other side is provided with a spring latch 15, which engages behind a cross-bar 14, and will hold the door either in the closed position shown in full lines, or in the open position shown at A in dotted lines. When in the latter position, the space beneath the grating communicates with an exhaust tube 13, through which the dirt &c. is drawn into a suitable receptacle &c., the cotton being prevented from being drawn through the grating, by reason of air being admitted to the chamber 9 at the hinged end of the door 10. When the grating is desired to be thoroughly cleaned, the door 10 may be swung vertically into the dotted position B.
Patent GB-189710980-A (GB)
Title: An Improvements in Screw Propeller Blades.
Inventor: FLEMING CHARLES
Filed: 1897-05-03
Granted: 1897-06-12
Abstract: 10,980. Fleming, C., and Thomson, J. R. May 3. Burning or uniting metals.-Relates to moans for preventing pitting and corrosion on the backs and tips of screw-propeller blades. The propeller is cast in any usual manner, and moulds M are taken of the tips for casting other tips of incorrodible metal. The blades D are now drilled at the tips C and broken off, exposing a clean surface for uniting the incorrodible metal ones, which are inserted in a mould M and fused or burnt on by pouring molten metal into the gutter E of the mould C.
Patent GB-189711619-A (GB)
Title: Improvements in and connected with Engines actuated by Mixed Products of Combustion and Steam.
Inventor: PILCHER PERCY SINCLAIR
Filed: 1897-05-10
Granted: 1898-04-16
Abstract: 11,619. Pilcher, P. S. May 10. Steam and furnace-gas engine furnaces.-The combustion chamber B of the generator is surrounded by the water space A'. Water or steam enters the coil C in the top of the combustion chamber, and the steam issues through the nozzle C<2> and passes with the combustion products through the pipe B<2> to the cylinder K of the motor. Some of the products may be conveyed by a perforated pipe B<3> below the surface of the water in A'. The air supplied to the furnace is pumped by the direct-acting pump G driven by the motor, and is heated in a jacket surrounding the generator before it issues with the fuel at F.
Patent GB-189711738-A (GB)
Title: Improvements in Mail Marking Machines.
Inventor: WAITE HENRY EDWARD
Filed: 1897-05-11
Granted: 1897-06-26
Abstract: 11,738. Waite, R. E. May 11. Postmarking-machines.-A packing-apparatus for postmarking-machines is shown in plan in Fig. 1. The marked letters p<1> are dropped edgewise upon an endless travelling band a, whence they pass along a vertical guide consisting of two straight portions 2 and 6 connected by a curved portion 3. The letters are packed against stops by discs e<1> which have portions cut away as shown in Fig. 1, and are mounted upon a vertical shaft e. When long letters are being packed, a fixed end stop f<1> is employed, and when short letters are being packed a removable end stop f is used.
Patent GB-189713503-A (GB)
Title: A New or Improved Spanner or Key.
Inventor: HEULLE PAUL GASTON
Filed: 1897-06-01
Granted: 1898-03-26
Abstract: 13,503. Heulle, P. G. Dec. 1, A.D. 1896, [date claimed under Sec. 103 of Patents &c. Act, A.D. 1883]. Spanners. - The head c of the spanner is pivoted at b to the handle a, and can be fixed i n a n y inclined position b the spring pawl e engaging the teeth f<1>. The jaw may be fixed or adjustable, as shown, by a worm k engaging with the toothed stem j of the sliding jaw i.
Patent GB-189805752-A (GB)
Title: A Detachable Axle Cylinder for Cycles.
Inventor: THORNHILL GEORGE
Filed: 1898-03-09
Granted: 1898-09-17
Abstract: 5752. Thornhill, G. March 9. Frames.-Bottom brackets or crank-axle cylinders are detachably secured to the cycle frames. The cylinder A has two tapered projections G which fit in holes in a downward extension H of the cycle frame, and are secured therein by screws as shown. The upper side of the cylinder r e s t s against the stays E, and is secured by screws to a piece connecting the stays.
Patent GB-189812097-A (GB)
Title: Appliance for Heating Objects, more particularly applicable to Tins Containing Preserves.
Inventor: SCHINDLER FRIEDRICH
Filed: 1898-05-27
Granted: 1899-03-25
Abstract: 12,097. Schindler, F. May 27. Cans.-Relates to means for heating objects such as tins containing preserves. ' In the form shown in Fig. 1, the hollow casing A is filled with caustic lime, or a mixture of lime and fragments of earthenware, a small annular water vessel C being arranged at the top. The casing is exhausted through a small opening, and then hermetically sealed. On driving a nail or the like through the casing and bottom of the vessel C, the water flows on to the lime, and the heat generated serves to warm a can or object D. In a modified arrangement, the heater consists of a vessel divided into compartments for lime and water and adapted to be placed in a vessel to be heated. The heater and object to be heated may be combined to form one tin.
Patent GB-189822452-A (GB)
Title: Improved Means and Appliances or Apparatus for the Supply of Refreshments after Receipt of Coin in Hotels, Boarding Houses and the like.
Inventor: SCOTT JOHN TWEEDY
Filed: 1898-10-25
Granted: 1899-08-26
Abstract: 22,452. Scott, J. T. Oct. 25. Sale apparatus; storage; coin action; delivery mechanism.-Supplying mineral waters, brandy, cigars, &c. in hotels and the like. The articles for sale are contained in racks A, B, in a case which may be on wheels, and they can be removed when flaps C, normally locked by spring bolts F, are turned down. A coin Q inserted in the slot D rests on a plate I and in a slot in the bolt F and spindle H of a milled head. On turning the milled head, therefore, the bolt F is withdrawn, allowing the flap C to open. The coin, on being freed from the slot E in the bolt F, falls into the coin receptacle.
Patent GB-189823812-A (GB)
Title: Improvements relating to the Joining or Connecting of Pipes.
Inventor: CLOUTIER NICOLAS
Filed: 1898-11-11
Granted: 1899-09-16
Abstract: 23,812. Cloutier, N., [known as Cloutier- Colson]. Nov. 11. Jointing with internal ferrules; sleeve joints.- The ends of lead and like pipes a, Fig. 1, are expanded into conical sleeves C, D by means of conical plugs or ferrules A. Washers F, G are screwed into the sleeves, and the joint is completed by screwing up the nut E. In a modification, a double-ended conical ferrule is used. Glass and other non-malleable pipes are fitted with conical sleeves A, Fig. 2.
Patent GB-189908414-A (GB)
Title: Improvements in Apparatus for Heating, Evaporating and Condensing, applicable for Heating Feed Water, Generating Steam, Condensing Exhaust in Steam Engines, or other Purposes.
Inventor: MAKIN EDWARD
Filed: 1899-04-22
Granted: 1900-03-03
Abstract: 8414. Makin, E. April 22. Instantaneous generators; feedwater, heating ; superheaters, steam.-Relates to apparatus for heating and evaporating, which is applicable for heating feedwater, generating or superheating steam, and other purposes, and consists of improvements on the steam-generator jacketed cones described in Specification No. 17,358, A.D. 1896. The cones a are formed of coiled tubing as shown in Fig. 1, and may be jacketed by suitable cast metal. Several such cones may be formed out of one length of pipe. These multiple cones c may be connected at the bottom to a common water supply, and at the top to a steam pipe or chest. For instantaneous steam generation or superheating, the coils are placed preferably inside flues or chambers and heated in any convenient way. Feedwater-heaters, as shown in Fig. 2, are similarly formed by the multiple coiled cones.
Patent GB-189910705-A (GB)
Title: Improvements in and connected with Incandescence Gas Burners.
Inventor: LERY JOSEPH BLASCO DE
Filed: 1899-05-23
Granted: 1899-06-24
Abstract: 10,705. LÚry, J. B. de. May 23. Incandescent gas burners.-Relates to improvements on the " tassel " burners described in Specification No. 9940, A.D. 1897, whereby the tassels may be more readily renewed, the deposition of soot upon the burners prevented, and economy effected in the quantity of the incandescent material used. According to the present invention, tassels, formed by rolling a strip d of the impregnated cotton or other material to the form shown in Fig. 3, bending it over the horizontal member of a U-shaped hook e, Fig. 4, and securing by a thread d<1>, are supported by the hooks e from a ring c, which is carried by thin arms b<1> from a stem b on the burner a. The ring c is of rectangular cross-section, and may be notched on its upper edge, to ensure the tassels being so placed relatively to the gas orifices a<2> that the flames impinge upon the curled edges of the strip d. The use of the ring c and the thin arms b<1> permits of the ready escape of the products of combustion, and, as on the inner side of the tassel the material only extends slightly beyond the binding thread d<1>, less material is required.
Patent GB-189915950-A (GB)
Title: Artificial Backgrounds for Photographs.
Inventor: WATSON THOMAS ROSS
Filed: 1899-08-04
Granted: 1900-06-09
Abstract: 15,950. Watson, T. R. Aug. 4. Mounting; finishing.-Consists in painting over the original backgrounds in photographs with paint or metallic composition. After the paint has been applied, a roughened or embossed appearance is given to it. The paint or composition may be applied to the back of a glass plate ; the print is then cut out and mounted on the glass.
Patent GB-189918232-A (GB)
Title: A New or Improved Coinfreed Game of Skill.
Inventor: PESSERS JOHN GERARD CORNELIUS
Filed: 1899-09-09
Granted: 1900-09-08
Abstract: 18,232. Pessers, J. G. C. M. Sept. 9. Games of chance and skill, apparatus for.-A ball B is shot np from the centre of the basin Y with the intention of sending it through a ring w, hung above in gimbals x, so that the vibration due to the operation causes it to swing and so increases the difficulty of the shot, for which purpose the whole apparatus may also be mounted so as to wobble. After passing through the ring the ball falls on a plate X, from which it returns to the basin by a pipe U. Actuating-mechanism.-The ball is projected by a plunger p when a lever L', after being depressed into the position shown in broken lines, is pulled up by a spring s' to strike the plunger. The striking-lever is depressed for action by a second lever L under a thrust-bar b, which is reset by a spring S. A lever may replace the thrust-bar. Coin action.-The coin Z dropped down a shoot s connects the two levers. In a modification, the coin lies flat in a pan formed by the lever ends. Fraud, preventing.-A pivoted ratchet bar L<11>, pulled by a spring S', engages a lug z on the etriking-lever L<1>, and must be struck away by a pin v on the operating-lever L. Delivery mechanism.-The following arrangement may be added :-A slide for delivering a prize is normally held by a snap latch H, Fig. 9, upon which rests a lever J having a leg K<1>, A rod K rising from the lever J bears a cup at the bottom of the return pipe U, into which the ball falls, and by its weight disengages the latch. In the manual operation of the slide to obtain the prize the ball is pushed out of the cup, and returns into position above the rod p.
Patent GB-189918489-A (GB)
Title: Process for Forming a Conducting Connection between Electrical Incandescence Bodies of Second Class Conductors with Conductors of the First Class.
Filed: 1899-09-13
Granted: 1899-10-28
Abstract: 18,489. Siemens Bros. & Co., [Siemens & Halske Aktiengesellschaft]. Sept. 13. Incandescent lamps.-Incandescence bodies which conduct only when hot are connected with metal wires, strips, tubes, or the like, by repeatedly coating the ends of the bodies with a suitable material, and heating them to white heat, before an oxyhydrogen blowpipe or otherwise, until the ends become plastic so that the metal wires &c. can be pushed into them. On cooling, the wires &c. are firmly held, and the joints conduct so well that in use they do not soften. The materials applicable are silicon, boron, and refractory metals such as manganese, molybdenum, chromium, titanium, nickel, and the platinum metals and alloys ; solid oxygen-free compounds of these may also be used, such as sulphides, phosphides, nitrides, or carbides. The ends are coated by heating them and dipping them in the powdered material, or by applying a paste of the material mixed with water or hydrocarbons.
Patent GB-189924917-A (GB)
Title: Improved Dental Forceps, Shears, Clippers, or the like, with Interchangeable Bits.
Inventor: BUDIN AUGUSTIN PIERRE
Filed: 1899-12-15
Granted: 1900-03-31
Abstract: 24,917. Budin, A. P. Dec. 15. Pliers, cutters, and pincers; handles. - Dental forceps are formed with detachable gripping - bits, the improvements being also applicable to any o t h e r instruments such as shears, clippers, &c. The handles a, b are pivoted together by a pin i, so that a projection h on a raised part f on one handle fits loosely into a socket g on a similarly-raised portion c on the other handle. The bits j, k are formed with flat portions which fit together so that a projection o on one bit fits into one of two recesses n on the other bit. When fitted together in this way, sockets m formed in the bits coincide, and can be fitted over the raised parts e, f of the handles when the handles are turned into the position shown. On now actuating the handles, the projections hand o slide into the sockets n and g respectively, and secure the parts together.
Patent GB-190001559-A (GB)
Title: Improvements in Devices for Automatically Closing and Opening Railway Gates.
Inventor: SIEGMANN HEINRICH
Filed: 1900-01-24
Granted: 1900-03-31
Abstract: 1559. Siegmann, H. Jan. 24. Crossing-gates opened and closed by trains. Treadles A, B, inclined towards both ends, are mounted on spring boxes 7 or on leaf or other springs and guided by vertical pins &c., and are adapted to be depressed by the wheel flanges or otherwise. Their motion is transmitted by bent levers 1 or by rack and pinion or other multiplying-gear through cords 2 or by pneumatic &c. means to the drums 17, 19, which drive the central drum 18 by projections K, and this drum winds up the cord 23 which pulls down the counterbalanced gate 22. The drum 18 is loose on a sleeve 21, which also, like the drums 17, 19, runs loose on a common shaft 16, but the ends of the sleeve and the hubs of the drums are inclined so that rotation of one drum forces the other sideways until it engages a disc 30 fast on the shaft 16. When the train passes the second treadle, the second drum drives the shaft so that a pin 31 on the disc 30 strikes a lever 32, which pulls the cord 15 so as to liberate the catch 13, which has engaged a pin 12 on the first-operated treadle to hold it down. The drums then can run freely, and are returned to their normal position by counterweighted cords 25 connected to their peripheries, and by levers 36<a>, 37<a> operated by counterweights. A fixed guide 20 holds the central drum 18 in the mid position. Springs may be used instead of counterweights, and other arrangements of clutches &c. for working the drums and the pull-off for the catches. Contacts 48 may be closed by the treadles to complete an electric circuit giving warning of the gates.
Patent GB-190002795-A (GB)
Title: Improvements in Apparatus for Drawing Off Measured or Unmeasured Quantities of Liquid.
Inventor: BRAKE ALFRED
Filed: 1900-02-12
Granted: 1901-02-05
Abstract: 2795. Brake, A. Feb. 12. Emptying jars &c.-The apparatus shown in Fig. 3 is for delivering measured quantities of beer or the like under pressure, but any quantity up to the measured quantity may be delivered, and inflow and outflow may take place simultaneously. The apparatus is also useful for delivering small quantities of syrups and the like, and a modified form is adapted to the delivery of liquids under less than atmospheric pressure from glass vessels or jars. The main principle of the invention is, that the measuring- vessel i is given a downward movement for delivery by means of a handle o, and an upward movement for refilling, by means of a spring g, about a valve rodj which moves with it a short distance and is then arrested so as to allow the discharge valve j<2> to open. A valve j' cuts off supply before the discharge begins. The supply pipe a' is lined with non-corrosive material, and the valve tube c with silver. k is a rubber seating for the top of the measure i, between which and the vessel, when depressed, the air under pressure escapes to the snift holes i<2>.