Patent SG-11201407028W-A (SG)
Title: St2l antagonists and methods of use
Inventor: DUFFY KAREN
IPC: C07K16/24
Filed: 2013-04-29
Abstract: (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 7 November 2013 (07.11.2013) WIPOIPCT (10) International Publication Number WO 2013/165894 A3 (51) International Patent Classification: A61K39/395 (2006.01) C07K16/24 (2006.01) (21) International Application Number: (22) International Filing Date: (25) Filing Language: (26) Publication Language: PCT/US2013/038637 29 April 2013 (29.04.2013) English English (30) Priority Data: 61/640,238 61/640,407 13/798,204 13/798,226 30 April 2012 (30.04.2012) US 30 April 2012 (30.04.2012) US 13 March 2013 (13.03.2013) US 13 March 2013 (13.03.2013) US (71) Applicant: JANSSEN BIOTECH, INC. [US/US]; 800/850 Ridgeview Drive, Horsham, Pennsylvania 19044 (US). (72) Inventors: DUFFY, Karen; 1400 McKean Road, Spring House, Pennsylvania 19477 (US). HEALY, Catherine; 1400 McKean Road, Spring House, Pennsylvania 19477 (US). LAMB, Roberta; 1400 McKean Road, Spring House, Pennsylvania 19477 (US). MALAVIYA, Ravi; 1400 McKean Road, Spring House, Pennsylvania 19477 (US). PRATTA, Michael; 1400 McKean Road, Spring House, Pennsylvania 19477 (US). FURSOV, Natalie; 1400 McKean Road, Spring House, Pennsylvania 19477 (US). LUO, Jinquan; 1400 McKean Road, Spring House, Pennsylvania 19477 (US). NASO, Michael; 1400 McKean Road, Spring House, Pennsylvania 19477 (US). TOR- NETTA, Mark; 1400 McKean Road, Spring House, Pennsylvania 19477 (US). WHEELER, John; 1400 McK­ ean Road, Spring House, Pennsylvania 19477 (US). WU, Sheng-Jiun; 1400 McKean Road, Spring House, Pennsylvania 19477 (US). HALL, LeRoy; 1000 Route 202S, Raritan, New Jersey 08869 (US). (74) Agents: JOHNSON, Philip S. et al.; Johnson & Johnson, One Johnson & Johnson Plaza, New Brunswick, New Jer­ sey 08933 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available)'. AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available)'. ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3)) — before the expiration of the time limit for amending the claims and to be republished in the event of receipt of amendments (Rule 48.2(h)) — with sequence listing part of description (Rule 5.2(a)) (88) Date of publication of the international search report: 27 March 2014 (54) Title: ST2L ANTAGONISTS AND METHODS OF USE PBS/PBS PBS/I L-33 CNT03914/IL-33 . . CNT05516/IL-33 m o\ 00 T-H rn i-H (57) Abstract: The present invention relates to ST2L antagonists, polynucleotides encoding the antagonists or fragments thereof, O and methods of making and using the foregoing. 10 15 20 25 MCH