baber/WOPTO huggingface dataset:
Patent EP-4284363-A2 (EP)
Inventor: SHUAI KE
IPC: A61K31/4015
Filed: 2022-01-25
Abstract: L'invention concerne des procédés et des compositions pour cibler des protéines SV2, comprenant SV2A, SV2B et SV2C. Certains aspects comprennent des procédés de traitement d'états associés aux cellules lymphoïdes innées du groupe 2 (ILC2s) comprenant, par exemple, les troubles auto-immuns, la pneumonie COVID-19, l'obésité et le cancer. L'invention concerne également des procédés de réduction de l'expression d'un récepteur de surface cellulaire par réduction de l'expression d'une protéine SV2 dans la cellule.
Patent EP-4253959-A2 (EP)
Inventor: SIEVERS STUART A
IPC: G01N33/68
Filed: 2019-02-14
Abstract: Isolated antigen binding molecules that specifically bind to a BCMA binding molecule are provided. The antigen binding molecules may be used in the methods provided herein. Specifically, monoclonal anti-idiotypic antibodies are provided which bind to the antigen-binding portion of a BCMA-binding molecule, in particular of anti-BCMA CARs.
Patent EP-4303419-A2 (EP)
Title: Systems and methods for bleed valve control in fuel systems
Inventor: MASTROCOLA NAISON E
IPC: F02C7/14
Filed: 2023-06-27
Abstract: A fuel system (100) includes a fuel metering unit (101) having a fuel inlet (108) and a fuel outlet (110) defining a flow path therebetween. The fuel system includes a bleed valve (106) in fluid communication with the flow path of the fuel metering unit (101). The fuel system includes a controller (104) in communication with the fuel metering unit (101) and the bleed valve (106) to send data thereto and/or receive data therefrom. The bleed valve (106) is configured and adapted to open or close depending on a command from the controller (104). The flow path is configured and adapted to be in selective fluid communication with a fuel system interstage (102) through the bleed valve (106).
Patent EP-4242838-A2 (EP)
Title: Instructions and logic to perform floating-point and integer operations for machine learning
Inventor: KAUL HIMANSHU
IPC: G06F9/30
Filed: 2018-03-26
Abstract: One embodiment provides for a processing unit comprising fetch and decode circuitry to fetch and decode a floating-point multiply-accumulate instruction; and execution circuitry to execute the floating-point multiply-accumulate instruction. The execution circuitry comprises mantissa multiplication circuitry, wherein the mantissa multiplication circuitry is shared with an integer datapath of the execution circuitry, wherein responsive to the floating-point multiply-accumulate instruction, the mantissa multiplication circuitry is to perform a multiplication operation with a mantissa value of each 16-bit floating-point data element of a first plurality of 16-bit floating-point data elements and a mantissa value of a corresponding 16-bit floating-point data element of a second plurality of 16-bit floating-point data elements to generate a corresponding plurality of mantissa results; exponent processing circuitry, responsive to the floating-point multiply-accumulate instruction, to perform an operation with an exponent value of each 16-bit floating-point data element of the first plurality of 16-bit floating-point data elements and an exponent value of each corresponding 16-bit floating-point data element of the second plurality of 16-bit floating-point data elements to generate a corresponding plurality of exponent results; circuitry to process the plurality of mantissa results and the plurality of exponent results to generate a corresponding floating-point product; and adder circuitry to generate a plurality of result floating-point values, each result floating-point value comprising a sum of one or more floating-point products of the plurality of floating-point products and a corresponding accumulated floating-point value of a plurality of accumulated floating-point values.
Patent EP-4300969-A2 (EP)
Inventor: CHEN JIANLE
IPC: H04N19/70
Filed: 2020-05-27
Abstract: A method of decoding includes receiving the coded video bitstream, the coded video bitstream containing reference picture lists; obtaining reference pictures for a current picture from the reference picture lists; setting a motion vector refinement flag to a first value to enable motion vector refinement for a current block of the current picture when the reference pictures are in a same layer as the current picture; setting the motion vector refinement flag to a second value to disable the motion vector refinement for the current block of the current picture when the reference pictures are in a different layer than the current picture; and refining a motion vector corresponding to the current block when the motion vector refinement flag is set to the first value.
Patent EP-0004588-A2 (EP)
Inventor: TRUNNER JOSEF
IPC: A62C13/00
Filed: 1979-03-16
Abstract: Auslösevorrichtung zur Oeffnung eines Ventils einer Brandlöschanlage durch einen linear beweglichen Auslösestössel (10) oder Auslösestift (20) bei Entriegelung einer vorgespannten Schraubenfeder (2), an deren einem Ende eine bewegliche Kugeldruckplatte (6) angeordnet ist, zwischen der und einer weiteren, fest angeordneten Kugeldruckplatte (9) Kugeln (7) angeordnet sind. Ein Spannstift (11) in der beweglichen Kugeldruckplatte (6) hält die Schraubenfeder (2) unter einer Torsionsspannung und die bewegliche Kugeldruckplatte (6) in einer solchen Winkelposition, dass die Kugeln (7) die beiden Kugeldruckplatten (6, 9) auf einer Ausgangsdistanz halten können. Bei elektromagnetischer Entriegelung des Spannstiftes (11) und Rückdrehung der Schraubenfeder (2) verdreht sich die bewegliche Kugeldruckplatte (6), so dass sich die Feder (2) axial entspannen kann und der Auslösestössel (10) auf das Auslöseelement des Ventils drückt und dieses öffnet. Konzentrisch zur ersten Schraubenfeder (2) ist ein weiterer Auslösestift (20) vorgesehen, der durch einen Handauslöseknopf (17) unabhängig von der elektromagnetischen Auslösung (4) manuell betätigt werden kann. Der Betriebszustand der Einrichtung ist visuell und durch Mikroschalter (16 und 24) überwachbar.
Patent EP-0005514-A2 (EP)
Inventor: BUSSING JURGEN DR
IPC: C08K9/04
Filed: 1979-05-11
Abstract: Feste Kombination eines flüssigen Kunststoff-Additivs in inniger Mischung mit einem festen Gleitmittel für die Verwendung in Polymeren.
Patent EP-0004396-A2 (EP)
Inventor: MULLER HASSO
IPC: B65D30/24
Filed: 1979-03-06
Abstract: 1. Bottom valve bag including a tube-shaped interior or exterior valve (20) substance-affixed to the charging aperture in the bottom which is, in particular, of the cross bottom type and which may be covered by an outer sheet (40), wherein said valve (20) comprises magnetic closure means (24).
Patent EP-0036924-A2 (EP)
Inventor: REICHERT GUNTER DIPL-ING
IPC: C01B25/14
Filed: 1981-01-26
Abstract: In einem Verfahren zur Kontrolle und gegebenenfalls Regelung der Standhöhe von flüssigem P2S5 in einem Kühlaggregat wird am unteren Ende eines geneigten Kühlaggregats, in der Nähe des dort zufließenden P2S5 ein inertes Gas eingeleitet, das man durch das flüssige P2S5 perlen läßt. Die sich dabei in Abhängigkeit von der jeweiligen Höhe des P2S5-Flüssigkeitsspiegels ergebende Druckdifferenz mißt man und benutzt die Änderungen dieser Druckdifferenz gegebenenfalls in bekannter Weise zur Regelung des Zuflusses an flüssigem P2S5 in das Kühlaggregat auf einen vorher bestimmten Bereich der Höhe des Flüssigkeitsspiegels in dem Kühlaggregat.
Patent EP-0037931-A2 (EP)
Inventor: SIMONS KAI PROF DR
IPC: A61K39/145
Filed: 1981-03-24
Abstract: Zur Herstellung von immunogen wirksamen lipid- und detergensfreien löslichen Aggregaten von amphiphilischen Membranproteinen von Parainfluenza-, Influenza- und Rhabdo-Viren mischt man den Virus mit einem nicht-ionischen oder Gallensäuren-Detergens, schichtet die Mischung in gepufferter wäßriger Salzlösung über einen detergensfreien Zuckergradienten, welcher seinerseits mit einer detergenshaltigen Zuckerlösung überschichtet ist, zentrifugiert bei mindestens 150 000 g, isoliert die proteinhaltige Fraktion, dialysiert gegen Pufferlösung und lyophilisiert die erhaltene Proteinmizellenlösung.
Patent EP-0039448-A2 (EP)
Inventor: LELING MENNO
IPC: E04C1/39
Filed: 1981-04-23
Abstract: For the production, in particular, of noise protection walls, simple and therefore economically producible slab-shaped concrete elements are used which are assembled by pressing together in such a way that all the concrete elements lie in planes which are at an acute angle to the plane of the wall. This results in a very irregular wall structure on the visible surfaces, and this structure offers a high degree of noise absorption, on the one hand, and is also aesthetically satisfying on the other. Planting of plants is also possible. <IMAGE>
Patent EP-0050187-A2 (EP)
Inventor: ROTH ADRIAN W DR
IPC: H01H33/91
Filed: 1981-06-26
Abstract: Ein bewegliches Kontaktstück (21) steht in Einschaltstellung mit einem festen Kontaktstück (15) im Eingriff und zugleich unter der Wirkung einer das bewegliche Kontaktstück (21) in die Ausschaltstellung drängenden Kraft. Das bewegliche Kontaktstück (21) ist mittels einer durch Überstrom auslösbaren Verriegelung (26) in Einschaltstellung arretierbar. Um die Anzahl beweglicher Teile auf ein Mindestmaß zu reduzieren, sowie erhebliche Verlustwärme erzeugende Teile zu vermeiden, weist die Verriegelung (26) einen im wesentlichen U-förmigen Riegel (27) aus einem weichmagnetischen Material auf, der das bewegliche Kontaktstück mit Spiel umgreift und quer zum Stromfluß in demselben verschiebbar gelagert ist. Mindestens eines der freien Schenkelenden (30, 31) des Riegels (27) ist mit einem Anschlag versehen, der in Einschaltstellung mit einer mit dem beweglichen Kontaktstück (21) mitbeweglichen Anschlagnase (34) zusammenwirkt. Der Schutzschalter eignet sich zum Einbau in Mittel- und Hochspannungsschaltanlagen.
Patent EP-0048382-A2 (EP)
Title: Röntgenaufnahmeeinrichtung mit einem von einer Bereitschaftsstellung in eine Aufnahmestellung verfahrbaren Filmträger
Inventor: ADELMEYER DIETER
IPC: G03B42/02
Filed: 1981-09-07
Abstract: Die Erfindung bezieht sich auf eine Röntgenaufnahmeeinrichtung mit einem von einer Bereitschaftsstellung in mindestens eine Aufnahmestellung und wieder zurück verfahrbaren Filmträger (4) mit verschiebbaren Spannbacken (40, 41, 42, 43) für die Halterung von Röntgenflmkassetten (44) unterschiedlichen Formats. Bei solchen Röntgenkassettenwechslern ist es erforderlich, daß die Einblendung des Strahlenkegels den Maßen der eingelegten Röntgenfilmkassette entspricht. Dabei sollte der Filmträger im Falle der Durchleuchtung ohne Schwierigkeiten aus dem Untersuchungsgerät herausgenommen werden können. Hierzu sieht die Erfindung vor, daß der Filmträger (4) und die Spannbacken (40, 41, 42, 43) mit Gebern (45, 46, 47) gekuppelt sind, wobei die Geber (45, 47) der Spannbacken (40, 43) in Abhängigkeit von der Spannweite eines jeden Spannbackenpaares in Verschiebungsrichtung des Filmträgers relativ zu letzterem verstellbar sind. Den Gebern sind dann Abnehmer (54, 56) zugeordnet, die zusammen mit einem Istwertgeber (32, 38, 39) für den Stellweg des Filmträgers an einer Meßwertverarbeitungsanordnung (57) angeschlossen sind. Eine ertindungsgemäße Aufnahmeeinrichtung ist insbesondere für den Einsatz in Flachblenden und Untertischzielgeräten geeignet.
Patent EP-0055348-A2 (EP)
Inventor: O'HARA ALMERIN CARTWRIGHT JR
IPC: H03K19/177
Filed: 1981-10-20
Abstract: A described dynamically reprogrammable logic array system includes an AND array (1) and an OR array (2) having an output register (3) at the output of the OR array. Commands stored in a load directory (9) specify subarrays within an array for repersonalization, an addressable location In load storage (10) containing the personality to be loaded into the subarrays. The load commands stored in the load directory are selectable by logic array output (R;r), by chaining or externally.
Patent EP-0045604-A2 (EP)
Inventor: SHIMAMOTO SUSUMU
IPC: H01F6/06
Filed: 1981-07-24
Abstract: A superconductive coil comprises pancake coils made of superconductive wires has cooling surface on which first and second fine grooves are respectively formed in different directions wherein said first fine grooves are formed in a step of preparing said superconductive wires and said second fine channels are formed on said pancake coils which is constructed by winding said superconductive wires having said first fine grooves in the form of a pancake.
Patent EP-0045212-A2 (EP)
Inventor: CHANGANI PUSHPKUMAR
IPC: H01R4/70
Filed: 1981-07-27
Abstract: A process for the production of a hollow heat-recoverable article provided with a functional insert which comprises:
     (a) deforming at least part of a body of fusion bondable polymeric material at a temperature below the softening point of the material to render it heat-recoverable,   (b) disposing the functional insert in contact with an exposed portion of the body,   (c) bonding one or more parts of the body to a substrate of fusion bondable polymeric material to produce the configuration of at least one hollow heat recoverable article with the functional insert located therein, and   (d) cross-linking the bond forming parts of the deformed body and the substrate to each other.   
     This provides a highly efficient way of installing the inserts in the recoverable articles.
Patent EP-0047588-A2 (EP)
Inventor: BLACK DAVID HAROLD ALEXANDER
IPC: H04J3/17
Filed: 1981-08-13
Abstract: A DSI transmission system is described in which noise signal contrast is mitigated by transmitting not only active channels but also channels which carry background noise, the resolution of the background noise channels being varied in dependence upon the number of channels transmitted. In the described system, the DSI transmission is effected in superframes each of which consists of an overhead information frame (Frame 1) and a plurality of digital message frames (Frames 2-28). The overhead information frame contains a word (ACW) indicating the transmission status of each channel during the superframe, a code (W1, W2) indicating the number of bits of each digital message, and maximum segment value information bits for each of the active channels which are transmitted using nearly instantaneous companding. Each of the remaining frames contains a digital message in respect of each active channel. Remaining space in these frames is occupied by digital messages in respect of the background noise channels, which are allocated to the frames by cyclic assignment and are transmitted using compact PCM encoding. For each superframe, active and background noise channels are determined using speech, echo, and off-hook detectors (109,111, and 113), and the number of bits of each digital message in the superframe is determined in dependence upon the total number of active and background noise channels.
Patent EP-0049627-A2 (EP)
Title: Byte-to-bit synchronizing circuitry
Inventor: HOLTEY THOMAS O
IPC: G06F13/00
Filed: 1981-10-05
Abstract: The circuitry synchronizes byte boundaries in a serial bit stream from a communications processor 10 with a byte timing signal BYTE from a device 26, the signal BYTE being in synchronism with bit timing pulses CLK but not byte boundaries. The bit stream starts with two all 1's bytes and an all 0's byte. The number of 1's in the second all 1's pulse following the BYTE signal is counted by a counter 200; the data bit stream is fed into a shift register 202; and the appropriate output is selected by a multiplexer 204 controlled by the stored count in counter 200, to achieve synchronization. 
     The unit 10 may be coupled to several devices 20, 22, 26 having differently timed BYTE signals, with the count from the counter in the active adapter 12, 14, 20 being fed to unit 10 to identify the active one of the devices.
Patent EP-0078962-A2 (EP)
Inventor: FERRI ERMANNO
IPC: G07C9/00
Filed: 1982-10-23
Abstract: The system provides means suited for distance operation with centralized control of a motor-vehicle accesses safety lock device, warning and antitheft installation and other relevant functions connection, including among said means at least one portable device for distance control and devices installed on the motor-vehicle to receive the control signal and to transform it for operation of said devices.
Patent EP-0082486-A2 (EP)
Inventor: KRONER KARL-HEINZ
IPC: C12Q1/00
Filed: 1982-12-16
Abstract: 1. Method for the kinetic process control of enzymatic reactions, characterised in that the reaction mixture, which contains the substrate to be hydrolysed and the hydrolytic enzymes, is divided into two streams by means of an ultrafiltration membrane, the ultrafiltration stream containing the cleavage products and the retentate stream containing the substrate, and the enzyme concentration is subsequently determined from the change in the substrate or product concentration in the retentate or ultrafiltration stream respectively.
Patent EP-0089666-A2 (EP)
Inventor: SEEBURG PETER H
IPC: C12P21/02
Filed: 1983-03-21
Abstract: Variants of human growth hormone, differing therefrom in structure but not essential activity, from a basis of the present invention and disclosure. In addition, the present invention involves a novel approach for isolating cDNA for a protein of unknown identity or detectability in native state.
Patent EP-0128239-A2 (EP)
Inventor: BACHMANN WOLFGANG
IPC: D21F1/10
Filed: 1983-10-11
Abstract: Beim Wickeln und Formen von Wendeln aus elastischem Kunststoff- oder Metalldraht, deren Windungen aus im wesentlichen geraden Windungsschenkeln und diese verbindenden Kopfbögen bestehen, vorzugsweise zum Fügen von Flächengebilden wie beispielsweise Sieb- bzw. Gliederbänder für Papiermaschinen od.dgl., wird der Draht aus einem Drahtvorrat zunächst zu von einem Wickelkegel wegwandernden Windungen mit dicht aneinanderliegenden Kopfbögen und parallelen, geraden Windungsschenkeln gewickelt. Daraufhin werden die Windungen einer Wärmeeinwirkung unterzogen und anschließend vereinzelt, woraufhin alle ihre auf einer Seite liegenden geraden Windungsschenkel abgeflacht und - nach Maßgabe der durch die Vereinzelung verwickelten Windungsabstände - verbreitert und dann zu einem Wendelvorrat gesammelt.
Patent EP-0114936-A2 (EP)
Inventor: HOEFERT PAUL
IPC: G01D11/26
Filed: 1983-10-13
Abstract: A display instrument having a housing (1) has a flange (2) on which a dial (3) and a covering disc (4) rest. A front ring (6) encompasses the covering disc (4), the dial (3) and the flange (2) and is joined to a clamping ring (5) on the opposite side of the flange (2) by a snap joint (8). This design makes it possible to assemble the covering disc (4) and the dial (3) extremely simply without a special machine. <IMAGE>
Patent EP-0097994-A2 (EP)
Inventor: PESSI ANTONELLO
IPC: C07K1/04
Filed: 1983-06-17
Abstract: This invention relates to a method for the solid-phase synthesis of polypeptides containing retro-inverted peptide bonds, using polydimethylacrylamide-co-acryloylsarcosi- methylester resin cross-linked with N, N'-ethylene-bisacrylamide as the insoluble support for lengthening the polypeptide chain in stages by the addition of suitable amino acid derivatives and/or peptides in succession. In particular, the method described in the present invention allows the easy preparation, on the polymer matrix, of monoacylated gem-diamino residues using the reagent I, I-bis (trifluoroace- toxy) iodobenzene in mixed aqueous-organic solvents.
Patent EP-0109147-A2 (EP)
Inventor: PETRIC PAUL FRANCIS
IPC: H01J37/317
Filed: 1983-09-08
Abstract: A charged particle beam lithography machine includes a beam source and beam steering and forming elements within an evacuated column (10). A stage assembly (30) for supporting a semiconductor wafer or mask is positioned in ambient and proximate the exit end of said beam steering and forming elements. A vacuum envelope apparatus (20) is affixed to the exit end of the beam steering and forming elements so that the outer surface or tip (23) of the vacuum envelope apparatus rests in spaced apart, close coupled opposition to the wafer or mask (28) supported on the stage. The vacuum envelope apparatus includes internal structural members (22) which define an internal vacuum processing zone and at least one surrounding intermediate vacuum zone (21). A graded vacuum seal is formed between the tip of the vacuum envelope and the mask or wafer. The seal extends from the internal vacuum processing zone to the external ambient. Lithographic operations are conducted on the mask or wafer as relative motion between the I stage assembly and beam steering and forming elements is accomplished.
Patent EP-0101330-A2 (EP)
Inventor: ENOMOTO HIROSHI
IPC: A61K31/47
Filed: 1983-06-10
Abstract: The invention relates to 2-quinolone derivatives represented by the following formula and salts thereof as well as manufacture methods therefor and pharmaceuticals consisting of one or more of said compounds as main ingredients 
<CHEM>
 wherein R<1>, R<2>, R<3>, R<4> and R<5> are same or different and are hydrogen, straight or branched lower alkyl with one to eight chain length, halogen, straight or branched lower alkoxy with one to five chain length, nitro, cyano, straight or branched halogeno lower alkyl with one to three chain length or COOR<6> where R<6> is hydrogen or straight or branched lower alkyl with one to three chain length, excluding the case where all of R<1>, R<2>, R<3>, R<4> and R<5> are hydrogen.
Patent EP-0109326-A2 (EP)
Inventor: DRAHOSLAV LIM
IPC: B29D11/00
Filed: 1983-10-27
Abstract: This disclosure describes the treatment of cellulose ad etate butyrate contact lenses which are rendered hydrophilic by contacting said lenses with a treating agent which increases the hydrophilicity of said lenses.
Patent EP-0121219-A2 (EP)
Inventor: BLOCK DALE A
IPC: G05G1/00
Filed: 1984-03-27
Abstract: A concealed mounting arrangement for attaching a handle to a rotatable stem without the need for using an exposed attachment screw is disclosed. In one embodiment, there is an adapter element fixedly mountable on the stem, and a handle element mountable on the adapter with a fit that allows relative rotational and axial movement therebetween. One of these elements is provided with a connecting pin that extends towards the other element and has an enlarged head near its outer end. The other of these elements is provided with a mounting slot comprising an access opening that faces said one element and receives the head therethrough when the elements are moved axially toward one another, an intermediate portion leading from the access opening in a direction of relative rotation between the elements and the intermediate portion has a shoulder engageable with the underside of the head during such rotation to prevent the elements from moving axially apart. An outwardly facing pocket portion is formed adjacentthefarend of the intermediate portion. It can receive the head when the head is aligned therewith after the elements have been moved axially apart. The engagement of the head and the pocket then serve to prevent relative rotation of the elements. A spring acts to hold the head in the pocket.
Patent EP-0147689-A2 (EP)
Inventor: KAIEDA TAKEJI
IPC: A61K39/00
Filed: 1984-12-05
Abstract: A method of inducing antitumor immunocytes which is simple in operation and suitable for inducing antitumor immunocytes having not only excellent cytotoxic activity against tumor cells but also high safety, which method comprises contacting leucocytes with an insoluble, antitumor immunocyte-inducing material capable of linking with T cells, said antitumor immunocyte-inducing material comprising an insoluble carrier and a ligand linked therewith. The induced antitumor immunocytes can be simply separated in substantially ligand-free form from the insoluble, antitumor immunocyte-inducing material. The obtained antitumor immunocytes have not only excellent cytotoxic activity against tumor cells but also high safety.