baber/WOPTO huggingface dataset:
Patent CA-2668131-A1 (CA)
Title: Antagonists of pcsk9
Inventor: HAMMOND HOLLY A
IPC: C07K16/40
Filed: 2007-11-02
Abstract: Antagonists of human proprotein convertase subtilisin-kexin type 9 ("PCSK9") are disclosed. The disclosed antagonists are effective in the inhibition of PCSK9 function and, accordingly, present desirable antagonists for the use in the treatment of conditions associated with PCSK9 activity. The present invention also discloses nucleic acid encoding said antagonists, vectors, host cells, and compositions comprising the antagonists. Methods of making PCSK9-specific antagonists as well as methods of using the antagonists for inhibiting or antagonizing PCSK9 function are also disclosed and form important additional aspects of the present disclosure.
Patent CA-2671273-A1 (CA)
Title: Aerial grapple apparatus and method for handling loose material
Inventor: FANDRICH HELMUT
IPC: B66C3/12
Filed: 2009-07-13
Abstract: A grapple, designed to grab, ferry, and dump loads of loose material such as mulch, comprising left and right frame members and finger assemblies with specially adapted curved fingers. Load arms connect the grapple to a supporting means, typically a helicopter, and also serve as anchors for finger cables and connecting arms cooperating with the finger assemblies to open and close the grapple. The method of grabbing prominently features using the shape of the fingers and the weight of the grapple and load to penetrate into and under the load. A latching mechanism cooperating with the connecting arms ensures stable ferrying until the remot e operator, generally the helicopter pilot, activates an electrical control switch to release the latch and dump the load.
Patent CA-2671351-A1 (CA)
Title: Compounds and methods for synthesis and purification of oligonucleotides
Inventor: WILL STEPHEN G
IPC: C07F9/02
Filed: 2007-12-21
Abstract: The present invention provides methods of extending nucleic acids and purifying target nucleic acids. The methods include the use of capping reagents to effect chain termination and provide a handle for purification via fluorous affinity methods.
Patent CA-2674308-A1 (CA)
Inventor: LORENZ WOLFGANG
IPC: C08G18/58
Filed: 2007-10-23
Abstract: A substance for coating metal surfaces, comprising organic resin components that are dissolved or dispersed in an organic solvent, or solvent mixture, having at least the following organic resin components: a) epoxy resin, present as polyether comprising hydroxyl groups, based on a bisphenol epichlorohydrin polycondensation product, b) blocked aliphatic polyisocyanate, c) unblocked aliphatic polyisocyanate, d) at least one reaction component, selected from polyesters comprising hydroxyl groups and poly(meth)acrylates comprising hydroxyl groups. The substance may also comprise at least one conductivity pigment. The invention further provides a method for coating a sheet metal with this substance, the respectively coated sheet metal, and the use thereof.
Patent CA-2674330-A1 (CA)
Title: Air pollution control apparatus and air pollution control method
Inventor: HONJO SHINTARO
IPC: B01D53/86
Filed: 2007-07-18
Abstract: An air pollution control apparatus according to the present invention reduces nitrogen oxides and oxidizes mercury in flue gas 16 discharged from a boiler by an ammonia denitrating catalyst. The air pollution control apparatus includes an economizer bypassing unit 15a that diverts high-temperature combustion gas 11 to a downstream side while bypassing an economizer 15 provided in a gas flue l0a for combustion gas 11 from the boiler, provided with an ammonium-chloride supply unit 101 that supplies powdery ammonium chloride (NH4Cl) to the economizer bypassing unit 15a. The air pollution control apparatus sublimates the ammonium chloride in an atmosphere at a high temperature of the combustion gas 11, and supplies hydrogen chloride and ammonium into the flue gas flue 102.
Patent CA-2675231-A1 (CA)
Inventor: YANG SHULING
IPC: C07K1/18
Filed: 2008-01-10
Abstract: A medicament useful for treating tumors or angiogenesis mediated diseases, medical compositions and kits comprising the medicament and a method for preparing the medicament are provided. The medicament contains complexes of a modifier and angiostatin or its fragments, which have longer in vivo half-life than non-modified angiostatin or its fragments. The modifier is selected from high molecular polymers, proteins or their fragments, polypeptides, small molecules and any other type of compounds.
Patent CA-2675326-A1 (CA)
Title: Double-cone sphincter introducer assembly and integrated valve assembly
Inventor: BLANCO ERNESTO E
IPC: A61M5/178
Filed: 2007-11-08
Abstract: A seal assembly includes a first seal, a second seal, and a positioning element. The first seal includes at least one longitudinal slot therein. The second seal includes at least one longitudinal slot therein and is positioned coaxially with the first seal. The positioning element is positioned coaxially with the first seal. The at least one longitudinal slot of the first seal is offset from the at least one longitudinal slot of the second seal in a radial direction from a longitudinal axis of the seal assembly. The seal assembly can be integrated with a closing valve. The seal assembly can also be integrated with a capsule.
Patent CA-2675603-A1 (CA)
Title: Methods and device for limiting battery power consumption in a wireless communication device
Inventor: JACKSON BRUCE KELLY
IPC: H04M1/73
Filed: 2008-02-19
Abstract: Systems, methods and apparatus are provided for limiting power consumption in a wireless communication device. The described aspects provide for power limiting thresholds to reserve power for, or limit power usage by, one or more predetermined applications executable by the wireless communications device. The described aspects are highly user-configurable, allowing a device user and/or a third party to define which applications have a battery power consumption limit or reserve, and the amount of battery power associated with the limit or reserve.
Patent CA-2676444-A1 (CA)
Title: Prodrugs of substituted 1,3-dioxanes and their uses
Inventor: ALBERTS PETERIS
IPC: A61K31/70
Filed: 2008-01-18
Abstract: The present invention relates to prodrugs of compounds containing 1,3-dioxane moiety, pharmaceutical compositions thereof, and the use of the compounds and compositions for the modulation of thromboxane A2 or a peroxisome proliferator-activated receptor. The prodrugs of the compounds, analogs, and pharmaceutically acceptable salts thereof, and pharmaceutical compositions can be used in the treatment and prevention of cancer.
Patent CA-2676891-A1 (CA)
Inventor: SIDOROV VLADIMIR
IPC: G09B15/00
Filed: 2009-08-28
Abstract: L'invention a pour nom CD audio/partitions et se caractérise par un CD de musique conventionnel sur lequel se trouvent les partitions des pièces musicales que comporte le CD. Cette invention est nouvelle en ce qu'elle rassemble sur un seul support, deux outils indispensables au musicien ou à l'amateur, qui existent séparément, soit la musique et la partition. Cette invention est utile car elle permet à l'auditeur d'avoir accès rapidement à la partition dont il a besoin pour jouer la musique qu'il écoute sur le CD. Cette invention est pratique et fiable car elle se présente sur un support d'usage courant, le CD audio, et garantit l'accès à une information de qualité qui demeurera présente sur le support aussi longtemps que la durée de vie du CD audio. Cette invention a aussi une valeur éducative qui va changer les pratiques d'usage du CD de musique, car elle fournit la méthode pour jouer et interpréter la musique du CD.
Patent CA-2678253-A1 (CA)
Title: Catheter anchoring system
Inventor: BIERMAN STEVEN F
IPC: A61M25/02
Filed: 1999-04-27
Abstract: An anchoring device for use with a medical article having an extending member projecting therefrom, the device comprises a retainer having a channel section extending along a longitudinal axis of the retainer and configured to receive at least a portion of the medical article, a longitudinal slot along said retainer through which the medical article can pass, the slot having a lateral width less than a diameter of the channel section, and at least one projection extending towards the longitudinal axis of the retainer and being configured to engage the extending member of the medical article in a manner inhibiting longitudinal motion of the medical article through the retainer and a flexible anchor pad having an adhesive bottom surface and a top surface, said retainer being supported by said anchor pad.
Patent CA-2680467-A1 (CA)
Title: Inhibitors of histone deacetylase
Inventor: PAQUIN ISABELLE
IPC: A61K31/4025
Filed: 2008-03-12
Abstract: The invention relates to the inhibition of histone deacetylase. The invention provides compounds and methods for inhibiting histone deacetylase enzymatic activity. The invention also provides compositions and methods for treating cell proliferative diseases and conditions. One aspect of the invention provides compounds of formula (1): (1), in which T, A and X are as described herein.
Patent CA-2680684-A1 (CA)
Inventor: MURAKAWA YUSUKE
IPC: A61K9/20
Filed: 2008-03-12
Abstract: The present invention provides a solid preparation containing 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-4-fluorobenzonitrile (compound (A)) or a salt thereof as a pharmaceutically active ingredient. Specifically, the present invention provides a solid preparation containing a granule composed of compound (A) or a salt thereof and an additive (excluding microcrystalline cellulose) and a tablet containing (a) a granule containing compound (A) or a salt thereof and microcrystalline cellulose, and (b) a tableting aid containing magnesium stearate and microcrystalline cellulose.
Patent CA-2680716-A1 (CA)
Inventor: KANJO WAJIH
IPC: B61H13/02
Filed: 2008-03-14
Abstract: A release holding mechanism for a railcar hand brake (10) includes a release shaft (70) rotatably mounted in the housing(14). A quick release handle (78)is rigidly secured to an external end of the release shaft for rotation therewith and manually rotatable into a release position to initiate the quick release of the railcar brake application. A release lever (110) cooperates with a driving mechanism (20) of the hand brake to effect quick release of the railcar brake application. A release ratchet wheel (102) is mounted for rotation with the driving mechanism. A release pawl (150) operably engages the release ratchet wheel when the driving mechanism rotated for releasing the brake application. A gravity weighted member (146) is disposed on and rigidly secured to the release lever for maintaining the release pawl, due to gravity, in a disengaged position relative to the release ratchet wheel when the driving mechanism is manually operable for effecting the brake application.
Patent CA-2682764-A1 (CA)
Title: Modular access control system
Inventor: SLAGEL ROBERT
IPC: B65D88/10
Filed: 2008-03-11
Abstract: An access control system includes first and second portable containers. The first portable container comprises a first sidewall opening and the second portable container comprises a second sidewall opening. The portable containers are arranged such that the first sidewall opening in the first portable container communicates with the second sidewall opening in the second portable container. The first portable container comprises a passing room disposed in the first portable container. The passing room includes a barrier device located in the walkway defining a first space between a first passing room opening and the barrier device, and a second space between the barrier device and a second passing room opening. The access control system is constructed such that when the access control system is disposed between a first area and an enclosed second area ingress and egress from and to the second area is controlled by the access control system.
Patent CA-2684309-A1 (CA)
Title: Painting pail system
Inventor: KENNEDY SAMUEL
IPC: B44D3/12
Filed: 2009-11-04
Abstract: A painting pail system includes a bucket, a bucket support, and a brace for the support. The bucket has an open top. The open top has a rod mounted thereacross. The support may be a U-shaped support having a pair of arms extending from a base, where the base is mounted to the substantially vertical brace so as to extend the arms substantially horizontally from the brace. The rod is mounted at its ends to distal ends of the arms, that is, distal from the base. The upper end of the brace includes a pair of mounting hooks spaced apart laterally so as to hook over an upper rung. The brace is elongate and its lower end is adapted to engage against a lower rung. A selectively engageable third hook latches the pair of mounting hooks onto the upper rung. The bucket may be removed from the support by releasing a latch arm mounted on the support.
Patent CA-2686662-A1 (CA)
Title: Method for manufacturing processed fish and processed fish
Inventor: DURAN VILA SALVADOR
IPC: A23L29/10
Filed: 2008-05-08
Abstract: The invention relates to a method for producing a processed fish product and to the resulting processed fish product. According to the invention, frozen raw fish is inserted into a vacuum cutter in which it is mixed together with concentrated fish stock in order to form a homogeneous paste of kneaded, minced, frozen raw fish paste. Food additives, such as phosphates that act as emulsions, and water in the form of ice are added to the mincer and mixed to form a homogeneous slurry. Said slurry is mixed with pre-cooked fish crumbs and/or chunks. The product can then be presented in two different ways, i.e. it can be dosed into a traditional can using a shaper and sterilised as in the normal manner for producing canned fish or shellfish or it can be frozen in moulds using plate freezers and subsequently cut and packaged in a manner suitable for a later final sterilisation treatment for the purpose of preservation.
Patent CA-2688002-A1 (CA)
Title: Managing status of search index generation in handheld book reader device
Inventor: REZTLAFF JAMES R
IPC: G06Q30/00
Filed: 2008-05-21
Abstract: Electronic items may be searched using search indices. Search indices may be generated for electronic items at a user device. In that case, a list of one or more electronic items stored in memory of the user device may be dis played, and a status of index generation for the electronic items stored in memory of the device may be presented.
Patent CA-2688594-A1 (CA)
Inventor: MARTIN RAINER E
IPC: C07D413/12
Filed: 2008-05-30
Abstract: This invention relates to compounds of the formula (I) wherein X is O or NR8, Y is CR7 or N, and R1 to R8 are as defined in the specification, and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are associated with the modulation of SST receptors subtype 5.
Patent CA-2688917-A1 (CA)
Inventor: KIM JIN PIL
IPC: H04N7/015
Filed: 2000-10-06
Abstract: A virtual channel table for broadcasting protocol and a method for broadcasting by using the virtual channel table includes identification information identifying and permitting discrimination of active and inactive channels contained in the virtual channel table. At a receiver, the virtual channel table transmitted from the transmitting side is parsed, thereby determining whether the current received channel is an active or inactive channel.
Patent CA-2689650-A1 (CA)
Title: Systeme et procede permettant l'inhibition de detection d'etiquettes desactivees au moyen de filtres de detection presentant un seuil adaptatif
Inventor: SOTO MANUEL A
IPC: G08B13/24
Filed: 2008-05-20
Abstract: La présente invention concerne un procédé, un système et un progiciel permettant l'inhibition de détection d'étiquettes désactivées. Le procédé, système et progiciel comprennent la réception d'un signal comportant un bruit d'environnement provenant d'au moins une étiquette, l'extraction d'une information de détection de signal comportant une valeur d'énergie de détection de signal à partir du signal reçu, l'extraction d'une information de désactivation de signal comportant une valeur d'énergie de désactivation à partir du signal reçu, et la détermination d'un échec de rapport de désactivation correspondant à la valeur d'énergie de détection de signal divisé par la valeur d'énergie de désactivation de signal. La génération d'un événement d'alerte est inhibée lorsque le rapport de désactivation est inférieur au seuil sélectionnable et la génération d'un facteur de bruit pour ajuster le seuil sélectionnable.
Patent CA-2690972-A1 (CA)
Inventor: PAPI DOMINIQUE
IPC: G06Q30/00
Filed: 2008-06-05
Abstract: L'invention concerne un procédé de fourniture d'assistance à  un utilisateur final d'une application logicielle en ligne s'exécutant à  partir d'un serveur Web. Alors que l'utilisateur final et le serveur  Web communiquent par l'intermédiaire d'au moins un réseau  de données, pendant une session Web lancée par l'utilisateur final  à partir d'une application logicielle client, l'application logicielle  en ligne fournit un moyen pour demander l'assistance d'un service  de dépannage sur au moins l'une des pages Web renvoyées à  l'application client. Lorsque l'utilisateur final active le moyen  pour demander une assistance, il obtient du serveur de l'application logicielle  en ligne un mot-clé associé à la session Web. L'utilisateur final  obtient en outre au moins un numéro de téléphone du service de  dépannage à appeler. Lorsque l'utilisateur final appelle le  service de dépannage par l'intermédiaire d'un réseau téléphonique,  le mot-clé est communiqué à un assistant. Une fois que l'assistant  s'est connecté avec succès au serveur Web, la session Web lancée  par l'utilisateur final est partagée avec l'assistant. Ensuite,  une transaction en cours avec l'application logicielle en ligne peut être  transférée à l'assistant qui l'achèvera  pour le compte de l'utilisateur final. Lorsque l'utilisateur final  d'une application logicielle en ligne rencontre des difficultés,  ou a des demandes spéciales, le transfert au service de dépannage  d'une transaction est grandement facilité par la seule communication  d'un mot-clé permettant à l'assistant de récupérer  rapidement la session Web afin d'aider l'utilisateur final ou d'achever  la transaction pour le compte de l'utilisateur final.
Patent CA-2691344-A1 (CA)
Inventor: MOLINE ANDREW J
IPC: C25D3/04
Filed: 2007-06-27
Abstract: An improved direct current chrome plating process which results in increased corrosion resistance as compared to conventional processes. Particularly, in comparison with conventional processes, an improved process as broadly contemplated herein can preferably include an additional processing step involving the application of a distinct chemical solution. This additional step, consequently, will lead to a chrome plated product having variant layers of chrome plating rather than the single layer as pro-duced conventionally.     An improved direct current chrome plating process which results in increased corrosion resistance as compared to conventional processes. Particularly, in comparison with conventional processes, an improved process as broadly contemplated herein can preferably include an additional processing step involving the application of a distinct chemical solution. This additional step, consequently, will lead to a chrome plated product having variant layers of chrome plating rather than the single layer as pro-duced conventionally.
Patent CA-2693622-A1 (CA)
Inventor: ALLEN LLOYD JR
IPC: G06F9/44
Filed: 2008-11-07
Abstract: Enabling end users to add their own hover help to extend hover help that is provided in a user interface, without having access to the code of the application. An end user can extend the application-provided hover help information to make it more helpful or tailored to his own needs.  The originally-provided hover help is retained, and may be rendered in addition to the user's appended hover help. Or, by specifying that the user-provided hover help is displayed in the same location as the originally-provided hover help, the user-provided hover help can be rendered such that the originally-provided hover help is at least partially obscured.
Patent CA-2694449-A1 (CA)
Inventor: FREEBURG THOMAS A
IPC: H04B7/15
Filed: 2008-07-31
Abstract: In accordance with the principles of the present invention, a radio system is provided. A master multiplexer is adapted to receiving an input signal. A slave multiplexer is adapted to send an output signal A timing master radio is connected to the master multiplexer and a timing slave radio is connected to the slave multiplexer, with the timing master radio and the timing slave radio adapted to communicate over a wireless connection. The timing master radio and timing slave radio use complementary TDD frame structures, controlled by the timing master radio, as is common in the art. The master multiplexer further comprising the timing mechanism that recovers timing embedded in the input signal, keeps track of the total number of bits received, and utilizes the total number of bits received thereby maintaining timing. The master multiplexer comprises a packet mechanism that generates a packet.
Patent CA-2696887-A1 (CA)
Inventor: CROCE CARLO M
IPC: G01N33/53
Filed: 2008-08-22
Abstract: Methods for assessing a pathological condition in a subject include measuring one or more markers where a difference is indicative of acute lymphoblastic leukemia (ALL) or a predisposition to ALL, uses and compositions are disclosed.
Patent CA-2698369-A1 (CA)
Inventor: LEVINE ZURIT
IPC: A61K39/00
Filed: 2008-09-03
Abstract: This invention relates to a novel target for production of immune and non-immune based therapeutics and for disease diagnosis. More particularly, the invention provides therapeutic antibodies against VSIG1, ILDR1, LOC253012, AI216611, C1ORF32 or FXYD3 antigens, which are predicted co-stimulatory family members and which are differentially expressed in cancers including, lung cancer, ovarian cancer, and colon cancer, and diagnostic and therapeutic usages. The use of these antibodies for modulating B7 costimulation and related therapies such as the treatment of autoimmunity are also provided. This invention further relates to the discovery of extracellular domains of VSIG1 and its variants, FXYD3 and its variants, ILDR1 and its variants, LOC253012 and its variants, AI216611 and its variants, and C1ORF32 and its variants awhich are suitable targets for immunotherapy, cancer therapy, and drug development.
Patent CA-2702281-A1 (CA)
Title: Imidazo[1,2-a]pyrimidine derivatives
Inventor: KLEIN MARKUS
IPC: A61K31/519
Filed: 2008-09-13
Abstract: The invention relates to new compounds of Formula (I), wherein W, T, R1, R2, R3, R4, R5, R6 and X7 have the meanings given in claim 1, the new compounds being suitable as antidiabetic drugs.
Patent CA-2702747-A1 (CA)
Inventor: LETA DANIEL P
IPC: C10G45/00
Filed: 2008-10-24
Abstract: This invention relates to an ultrafiltration process for separating a heavy hydrocarbon stream to produce an enriched saturates content stream(s) utilizing an ultrafiltration separations process.  The enriched saturates content streams can then be further processed in refinery and petrochemical processes that will benefit from the higher content of saturated hydrocarbons produced from this separations process. The invention may be utilized to separate heavy hydrocarbon feedstreams, such as whole crudes, topped crudes, synthetic crude blends, shale oils, oils derived from bitumen, oils derived from tar sands, atmospheric resids, vacuum resids, or other heavy hydrocarbon streams into enriched saturates content product streams. The invention provides an economical method for separating heavy hydrocarbon stream components by molecular species instead of molecular boiling points.