baber/WOPTO huggingface dataset:
Patent WO-2023173116-A1 (WO)
Title: Il-12 liée à la membrane pour immunothérapie cellulaire
Inventor: PRICEMAN SAUL J
IPC: C12N5/078
Filed: 2023-03-10
Abstract: La présente invention concerne, entre autres, <i />des cellules exprimant à la fois un récepteur antigénique chimérique (CAR) et une IL-12 liée à la membrane et l'utilisation de ces cellules pour cibler et traiter des cancers (par exemple, des tumeurs solides et des cancers exprimant CD19, CD22, BCMA, PSCA, HER2, TAG-72 et PSCA). L'invention concerne également des cellules exprimant une IL-12 liée à la membrane.
Patent WO-2023178130-A1 (WO)
Title: Agents de dégradation de protéine sos1, compositions pharmaceutiques et applications thérapeutiques
Inventor: ERDMAN PAUL E
IPC: A61K31/519
Filed: 2023-03-15
Abstract: L'invention concerne des agents de dégradation de protéine SOS1, par exemple, un composé de formule (I) comprenant une fraction de liaison à l'ubiquitine ligase E3, et des compositions pharmaceutiques de ceux-ci. L'invention concerne également des procédés d'utilisation de ceux-ci pour traiter, prévenir ou améliorer un ou plusieurs symptômes d'un trouble, d'une maladie ou d'un état à médiation par SOS1, notamment le cancer du côlon, le cancer colorectal, le cancer du poumon ou le cancer du pancréas.
Patent WO-2024015779-A1 (WO)
Title: Informing a user of anticipated insulin delivery actions and providing recommended user actions
Inventor: LEE JOON BOK
IPC: G16H20/17
Filed: 2023-07-11
Abstract: Exemplary embodiments may determine anticipated basal insulin delivery action to a user from an insulin delivery device over a future time window. Indications of the anticipated basal insulin delivery action over the future time window may be output to the user. The exemplary embodiments may determine the anticipated basal insulin delivery action over the future time window based on a rate of change (ROC) of glucose level of the user by the insulin delivery device, a most recent ("current") glucose level for the user and insulin on board (IOB) for the user. The exemplary embodiments may also determine whether the user is likely to experience a undesired high glucose level (e.g., hyperglycemia) and/or an undesired low glucose level (e.g., hypoglycemia) during the future time window. The exemplary embodiments may output recommendations based on the projected glucose levels of the user over the future time window.
Patent WO-2024020490-A1 (WO)
Title: Foveated down sampling of image data
Inventor: WU CHIHSIN
IPC: G06T1/20
Filed: 2023-07-20
Abstract: A foveated down sampling (FDS) circuit for down sampling of pixels in images. The FDS circuit down samples a first subset of pixels of a same color in an image using first scaling factors to generate first down sampled pixels in a first down sampled version of the image. The FDS circuit further down samples a second subset of the first down sampled pixels of the same color using second scaling factors to generate second down sampled pixels of the same color in a second down sampled version of the image. Pixels from the first subset are arranged in a first direction, and pixels from the second subset are arranged in a second direction.
Patent WO-2024020533-A1 (WO)
Title: Immunogenic compositions for treating or preventing actinomycetia infections
Inventor: HOLDER JASON
IPC: A61K39/04
Filed: 2023-07-21
Abstract: The present disclosure features methods for treatment or prevention of actinomycetia (e.g., corynebacteriales) infections, e.g., caused by mycobacterial cells, residing within a host cell (e.g., a mammalian cell, e.g., immune cell, e.g., macrophage or dendritic cell). The methods include contacting actinomycetia cells with a mixture of lytic enzymes to rupture the bacterial cells, thereby releasing biological particles and fragments thereof. The degradation products can be used as an immunogenic composition to treat or prevent future infection.
Patent WO-2013082636-A1 (WO)
Title: Exploitation de dépôts carbonés
Inventor: HAHN HANS HELMUT
IPC: E21B43/24
Filed: 2012-11-28
Abstract: L'invention concerne un procédé d'exploration et/ou d'exploitation de dépôts carbonés tout en réduisant les dommages causés à la surface et les caractéristiques de morts-terrains et/ou d'autres effets négatifs accompagnant l'exploitation de dépôts carbonés. La première étape prépare le dépôt pour l'extraction de méthane, suivie de l'extraction et de l'utilisation du méthane relâché et d'autres espèces volatiles. Une étape intermédiaire évalue les informations collectées dans la première étape pour une étape ultérieure suivant de façon synergique la première étape et utilisant la même infrastructure pour une gazéification souterraine  in situ , en utilisant des techniques de gazéification/vaporisation thermochimiques et/ou microbiologiques. Les gaz des deux étapes sont utilisés localement ou sont transportés ailleurs par conduite comme source d'énergie ou comme matière première chimique.
Patent DK-201470285-A1 (DK)
Title: Pelt board
Inventor: PEDERSEN KURT
IPC: C14B15/06
Filed: 2014-05-15
Abstract: A pelt board (11) is disclosed for stretching and drying of tubular pelts (5), the pelt board (11) having a tip end (4) from which the pelt is drawn onto the pelt board (11) and a foot end (2), wherein the pelt board (11) has a lower part (8) nearest the foot end (2) w5here the outer cross-sectional circumference of the pelt board (11) is substantially constant and an upper part (9) between the lower part (8) and the tip end (4), where the outer cross-sectional circumference of the upper part (9) gradually decreases towards the tip end (4), wherein the longitudinal extent (L1) of the lower part (8) is in the range of 36 to 50 cm, more preferably in the range of 40 to 45 cm and the lon1g0itudinal extent (L1) of the lower part (8) constitutes more than 0.25 and no more than 0.35 of the of the overall extent of the pelt board (11). Furthermore is disclosed an extension piece for connecting with a standard pelt board and fat-absorbing inner bags (13, 19) for use with the pelt board (11).
Patent DK-201570782-A1 (DK)
Title: Hearing aid with a flexible carrier antenna and related method
Inventor: RASMUSSEN BENNY
IPC: H04R25/00
Filed: 2015-12-01
Abstract: A hearing aid having an electrical assembly, the electrical assembly includes a printed circuit board having a first board surface and a second board surface, the printed circuit board having a first pad in a first pad region on the first board surface, the first pad region having a first board normal; a flexible printed circuit board comprising an antenna, the antenna having a first terminal in a first terminal region on a first flexfilm surface of the flexible printed circuit board, the first terminal region having a first terminal normal; and first electrically conductive material connecting the first pad and the first terminal, and wherein the first terminal normal and the first board normal forms a first angle that is anywhere from 30° to 150°.
Patent DK-202000168-A1 (DK)
Title: Lifting Apparatus
Inventor: JOSEF FAHOUM
IPC: E01C19/52
Filed: 2020-02-11
Abstract: A lifting apparatus (100) for lifting an object (102) is disclosed. The lifting apparatus (100) comprises an elongated member (104) and an intermediate member (106). The elongated member (104) having a pair of slots (122 and 124), which are separated by a wedge section (110) at a bottom portion. The intermediate member (106) is bisected at its middle portion (130) into two members (126 and 128) with each barb (118). The intermediate member (106) is disposed within a recess (105) of the elongated member (104) by applying force, whereby the applied force causes the barbs (118) to expand outwards via the slots (122 and 124) for securing the object (102). The elongated member (104) and the intermediate member (106) are secured via a locking rod (108) and a chain sling (120) is secured to both ends of the locking rod (108) for safely lifting the object (120).
Patent DK-202070679-A1 (DK)
Title: Marine seismic acquisition with a support vessel
Inventor: Erik GODØY
IPC: G01V1/38
Filed: 2020-10-07
Abstract: The present invention relates to a system for towing a tow (12) comprising seismic sensor cables (2) in completely or partly ice-covered water (8), where a towing vessel (1) tows the tow, and the tow at one side comprises a deflector (4) pulling sideways away from the tow (12), where a support vessel (7) is connected to and tows the deflector (4). The invention also relates to a method for towing a tow (12) comprising seismic sensor cables (2) in completely or partly ice-covered water (8), where a towing vessel (1) tows the tow, and the tow on one side comprises a deflector (4) pulling sideways away from the tow (12), where a support vessel (7) is connected to the deflector (4), and the deflector is towed by the support vessel.
Patent DK-202100544-A1 (DK)
Title: Tower deformation zone
Inventor: PETER SIGFRED MORTENSEN
IPC: F03D13/20
Filed: 2021-06-28
Abstract: A tower for supporting a nacelle to form a wind turbine is provided. The tower comprises: a plurality of tower sections connected together to form the tower, wherein at least one tower section is a deformation tower section configured such that it is predisposed, relative to the remaining plurality of tower sections, to deform if the nacelle should be dropped onto the tower while being mounted thereon, such that energy transferred to the tower resulting from the impact of the nacelle on the tower can be absorbed by the deformation tower section in a predictable and controlled manner.
Patent PH-12014501456-A1 (PH)
Title: Pyrazinecarboxamide compound
Inventor: TAKAHIRO MATSUYA
IPC: C07D471/10
Filed: 2014-06-24
Abstract: [Problem] To provide a compound that is useful as an inhibitor of EGFR T790M mutation kinase activity. [Solution] The inventors studied compounds having an inhibiting effect against EGFR T790M mutation kinase and perfected the invention upon confirming that a pyrazine carboxamide compound has an inhibiting effect against EGFR T790M mutation kinase. The pyrazine carboxamide compound of the invention has an inhibiting effect against the EGFR T790M mutation kinase and can be used as a prophylactic and/or therapeutic agent for EGFR T790M mutation-positive cancer, EGFR T790M mutation-positive lung cancer, EGFR T790M mutation-positive non-small cell lung cancer, EGFR T790M mutation protein-positive cancer, and EGFR T90M mutation protein-positive lung cancer.
Patent PH-12014502221-A1 (PH)
Title: Prasugrel-containing immediate release stable oral pharmaceutical compositions
Inventor: FEH�R, ANDR�S
IPC: A61K9/16
Filed: 2014-10-02
Abstract: Prasugrel containing quickly released stable oral pharmaceutical compositions containing micronized prasugrel base, and starch or a starch derivative, and processes for the preparation thereof, and the use thereof for treating atherothrombotic events of patients suffering from acute coronary syndrome in which patients were subjected to percutaneous.
Patent PH-12014502228-A1 (PH)
Title: Plants having one or more enhanced yield-related traits and method for making same
Inventor: CHRISTOPHE REUZEAU
IPC: C07K14/195
Filed: 2014-10-02
Abstract: A method for enhancing yield-related traits in plants by modulating expression in a plant of a nucleic acid encoding a flavodoxin polypeptide in a specific way is provided and unkown constructs useful in performing the method are provided. Plants having the expression of a nucleic acid encoding a flavodoxin polypeptide modulated by a particular type of promoter, which plants have enhanced yield-related traits compared with control plants, are also provided.
Patent PH-12014502876-A1 (PH)
Title: Pharmaceutical composition containing fimasartan and hydrochlorothiazide
Inventor: HAK KIM JE
IPC: A61K31/4422
Filed: 2014-12-23
Abstract: The present invention provides: a pharmaceutical composition having a superior physical property since fimasartan and hydrochlorothiazide, which are main components of a composite, have superior content uniformity; and a preparation method thereof.
Patent PH-12015501957-A1 (PH)
Title: Pharmaceutical composition of s-ketamine hydrochloride
Inventor: BASSTANIE ESTHER D G
IPC: A61P25/24
Filed: 2015-09-04
Abstract: The present invention is directed to an aqueous formulation of S-ketamine hydrochloride, preferably for nasal administration, wherein the formulation does not contain an antimicrobial preservative.
Patent PH-12016501452-A1 (PH)
Title: Flux machine
Inventor: KEITH KLONTZ
IPC: H02K1/17
Filed: 2016-07-22
Abstract: A flux machine includes a stator and a rotor. A set of electrical coil assemblies with side surfaces and sets of plural permanent magnets are arranged circularly. Pole faces of the magnets are positioned adjacent to and spaced apart from side surfaces of permeable cores of the coil assemblies. In each coil assembly a pair of like pole faces of the magnets mutually face across the permeable core and a third magnet pole face faces transversely relative to the mutually facing pole faces of the pair of magnets.
Patent PH-12016502481-A1 (PH)
Title: Image coding method, image coding apparatus, image decoding method and image decoding apparatus
Inventor: HISAO SASAI
IPC: H04N19/91
Filed: 2016-12-13
Abstract: An image encoding method comprising: a binarization step (S401) in which the LAST position information is binarized to generate either (i) a binarized signal which includes a first signal having a length equal to or shorter than a predetermined maximum length and which does not include a second signal, or (ii) a binarized signal which includes a first signal having a predetermined maximum length and a second signal; a first encoding step (S402) in which the context for each binary symbol in the first signal is switched according to the bit position of the binary symbol, and the binary symbols are arithmetically encoded; and a second encoding step (S404) in which if the binarized signal includes a second signal, the second signal is arithmetically encoded using a fixed probability. In the first encoding step, if the first signal has the predetermined maximum length, the binary symbol at the final bit position in the first signal is arithmetically encoded using a context exclusive to the final bit position.
Patent PH-12017050124-A1 (PH)
Title: Exhaust gas control apparatus for internal combustion engine
Inventor: TSUKAMOTO YOSHIHISA
IPC: F01N3/20
Filed: 2017-12-04
Abstract: PROBLEM The present invention has an object to suitably recover ionic valence of transition metal ions included in an SCR catalyst, in an exhaust gas control apparatus including the SCR catalyst. SOLUTION TO PROBLEM In an exhaust gas control apparatus for an internal combustion engine in the present invention includes: an SCR catalyst including transition metal ions for reducing NOX in exhaust gas with NH3 as a reducing agent; detection means for detecting temperature of the SCR catalyst; and a heater configured to heat the SCR catalyst, when NOX does not flow into the SCR catalyst, and the temperature detected by the detection means is below a first temperature that is a temperature causing exhibition of valence recovery of transition metal ions, the heater is controlled such that the SCR catalyst is heated up to a first temperature or above and that the SCR catalyst is maintained at or above the first temperature for a prescribed period so as to achieve valence recovery of the transition metal ions put in a deteriorated state.
Patent PH-12018000163-A1 (PH)
Title: Viral molecular network architecture and design
Inventor: FORDE RICHARD A
IPC: H04W88/00
Filed: 2018-06-13
Abstract: The present disclosure relates to a wireless communication device, a high-speed, high capacity dedicated mobile network system, and a method for transmitting information streams across a molecular network to end users utilizing a Millimeter Wave RF [the frequency band is in the order of 30 to 3300 gigahertz (GHz)range, at the upper end of the millimeter wave spectrum and into the infrared spectrum] system architecture that use a Gyro TWA ultra-high power amplifier repeating device in a special design grid fashion across cities, suburbs, and villages around the world that receives and re-amplifies and retransmits the V-ROVERs, Nano-ROVERs, Atto-ROVERs, Protonic Switches, Nucleus Switches RF signal and certain Touch Point devices that are equipped with the Attobahn IWIC chips. The present enclosure carry out aforementioned functions without using IEEE 802 LAN, ATM or TCP/IP connection-oriented standards and protocols.
Patent PH-12018500475-A1 (PH)
Title: Control device, control method, program, and control system
Inventor: TAKATSUKA HIROMASA
IPC: H04Q9/00
Filed: 2018-03-05
Abstract: A control device having an acquisition unit for acquiring the state of a vehicle upon receiving a control request, an execution feasibility determination unit for determining whether the acquired vehicle state is a state in which the control request can be safely executed, an execution control unit for executing the control request when determined that the state is a state in which safe execution is possible, and a transition control unit for controlling so as to transition the vehicle state to a state in which safe execution is possible, wherein the execution feasibility determination unit operates the transition control unit when determined that the state is a state in which safe execution is not possible, and after the execution feasibility determination unit determines that the state is a state in which safe execution is possible, the execution control unit executes the control request.
Patent PH-12018501373-A1 (PH)
Title: Novel phosphinane and azaphosphinane derivatives, method for preparing same and pharmaceutical compositions containing same
Inventor: GLOANEC PHILIPPE
IPC: C07F9/6584
Filed: 2018-06-26
Abstract: Compounds of formula (I) in which: Ak1 represents an alkyl chain, X represents -(CH2)m-, -CH(R)-, -N(R)-,-CH2-N(R)-, -N(R)-CH2- or -CH2-N(R)-CH2-, m and R are as defined in the description, R1 and R2 each represent H when X represents -(CH2)m-, -CH(R)-, -N(R)-, -CH2-N(R)- or -N(R)-CH2-, or indeed together form a bond when X represents -CH2-N(R)-CH2-, R3 represents NH2, Cy-NH2, Cy-Ak3-NH2 or piperidin-4-yle, Cy and Ak3 are as defined in the description, R4 and R5, identical or different, each represent H or F, the optical isomers of same, and the pharmaceutically acceptable acid addition salts thereof. The invention also relates to drugs containing same.
Patent PH-12018501909-A1 (PH)
Title: Hair dyeing instrument
Inventor: ASAKURA HIROMI
IPC: A45D24/00
Filed: 2018-09-07
Abstract: A hair dyeing instrument 1 is equipped with: a comb member 10 that has a plurality of comb teeth 12; and a nipping member 20 that is rotatably mounted to the comb member 10 so as to nip hair between itself and the comb member 10, and which is capable of scooping hair in a stripe-like manner with the tips of a plurality of comb teeth 12, wherein: the comb member 10 is provided with a support member 30 which rotatably supports the nipping member 20 and a moving member 40 which is mounted to the support member 30 in a reciprocally movable manner; the support member 30 and the moving member 40 each have a plurality of first protrusions 32 and second protrusions 42; the comb teeth 12 are constituted with the first protrusions 32 and second protrusions 42; and the width of an overlap between the first protrusions 32 and the second protrusions 42 changes in response to a movement of the moving member 40 relative to the support member 30.
Patent PH-12019500683-A1 (PH)
Title: Method and device for determining areas of interest based on geolocation data
Inventor: ZHANG DEPIN
IPC: H04L29/08
Filed: 2019-03-28
Abstract: The present application provides a method and a device for determining an area of interest based on geolocation data. The method comprises: performing gridding on a map area to be processed; recording a grid value of each grid within a preset duration, the grid value being the number of users that report geolocation data within a corresponding grid; selecting a grid value greater than a preset threshold from the recorded grid values; determining location points in the grid corresponding to the selected grid value; calculating, according to the location points and based on a preset algorithm, to obtain a curve comprising all of the location points; and determining an area in the curve as an area of interest. By using embodiments of the present application, areas of interest are automatically determined by using geolocation data accurately reported by users, thus avoiding low efficiency and high costs associated with having to manually demarcate areas of interest.
Patent PH-12019501254-A1 (PH)
Title: Small molecule inhibitors of the jak family of kinases
Inventor: KREUTTER KEVIN D
IPC: C07D471/14
Filed: 2019-06-06
Abstract: 2-((1r,4r)-4-(imidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(6H)-yl)cyclohexyl)acetonitrile compounds, pharmaceutical compositions containing them, methods of making them, and methods of using them including methods for treating disease states, disorders, and conditions mediated by JAK, such as inflammatory bowel disease.
Patent PH-12019502204-A1 (PH)
Title: An apparatus for detecting fire and preventing explosion of transformer and a method thereof
Inventor: WAKCHAURE V K
IPC: H01F27/40
Filed: 2019-09-24
Abstract: The present disclosure provides an apparatus for detecting fire and preventing explosion of a transformer. The apparatus comprises at least one voltage variation detection unit and an over current detection unit for providing first and second input signal to at least one control unit. Also, at least one surge detection unit and at least one Rapid Pressure Rise Relay is provisioned in the apparatus, to provide a third input signal the control unit. One or more circuit breakers is configured to provide a fourth input signal to the control unit. The at least one control unit receives either one of the first input signal, the second input signal, the third input signal and the fourth input signal, thereby generating a control signal for operating a drain valve and a gas release valve.
Patent PH-12020550215-A1 (PH)
Title: P38 Kinase Inhibitors Reduce Dux4 And Downstream Gene Expression For The Treatment Of Fshd
Inventor: CACACE ANGELA MARIE
IPC: G01N33/15
Filed: 2020-04-03
Abstract: The disclosure relates to methods and compositions including p38 kinase inhibitors and agents that regulate expression of DUX4 and downstream genes including but not restricted to ZSCAN4, LEUTX, PRAMEF2, TRIM43, MBD3L2, KHDClL, RFPL2, CCNAl, SLC34A2, TPRXl, PRAMEF20, TRIM49, PRAMEF4, PRAME6, PRAMEFl5, or ZNF280A. Methods useful for treating a disease associated with abnormal DUX4 and downstream gene expression (e.g., Fascioscapulohumeral muscular dystrophy) are disclosed.
Patent PH-12020550520-A1 (PH)
Title: Aqueous gel-like composition
Inventor: TAIJI YOSHIMI
IPC: A61L9/01
Filed: 2020-04-30
Abstract: Provided is an aqueous gel-like composition which is capable of increasing the intensity of a fragrance, and which has excellent emulsion stability and gel stability even when containing a relatively high concentration of a volatile oily component. By using a gelling agent in combination with organic bentonite, a relatively large amount of a volatile oily component is stably emulsified and dispersed in an aqueous solvent while suppressing the amount of a surfactant added, and a gel having a high gel strength and excellent stability is formed.
Patent PH-12020550966-A1 (PH)
Title: Liver specific delivery-based entecavir prodrug, nucleoside cyclic phosphate compound, and application thereof
Inventor: XI ZHIJIAN
IPC: A61P31/12
Filed: 2020-06-22
Abstract: Disclosed is a liver specific delivery (LSD)-based entecavir antiviral prodrug, i.e., a nucleoside cyclic phosphate compound, and the application thereof. Specifically, disclosed are a compound as represented by formula (I) and isomers, pharmaceutically acceptable salts, hydrates, and solvates of the compound, and a corresponding pharmaceutical composition. Also disclosed is the application of the compound of the present invention, used separately or used in combination with other antiviral drugs, against viruses, especially the application against hepatitis B virus (HBV).