baber/WOPTO huggingface dataset:
Patent DE-69022744-D1 (DE)
Inventor: ALKER DAVID
IPC: C07D401/06
Filed: 1990-11-28
Granted: 1995-11-02
Abstract: PCT No. PCT/EP90/02039 Sec. 371 Date Jul. 2, 1992 Sec. 102(e) Date Jul. 2, 1992 PCT Filed Nov. 28, 1990 PCT Pub. No. WO91/10650 PCT Pub. Date Jul. 25, 1991.According to the invention there is provided a compound of formula (I): R1-O(CH2)mA(CH2)nXR or a pharmaceutically acceptable salt thereof, wherein R1 is a group of formula (a or b) where Z is -(CH2)2-, -CH=CH-, -CH2-S- or -CH2-O-; R is a group of formula (c, d or Het) and A is a group of formula (e, f or g) in which the N atom is attached to the group (CH2)n; m is 1 or 2; n is an integer of from 1 to 4; p is 1, 2 or 3; R2 and R3 are each independently hydrogen, C1-C4 alkyl, hydroxy-(C1-C4 alkyl), hydroxy, C1-C4 alkoxy, halo, trifluoromethyl, nitro, cyano, sulphamoyl, -CO(C1-C4 alkyl), -OCO(C1-C4 alkyl), carboxy, -CO2(C1-C4 alkyl), -CH2)qCONR4R5, - (CH2)qOCONR4R5, -CH2)qNR6R7 or -NHSO2NH2 in which R4 and R5 are each independently H or C1-C4 alkyl, q is 0, 1 or 2, and either R6 and R7 are each independently H or C1-C4 alkyl or R6 is hydrogen and R7 is -SO2(C1-C4 alkyl), -CO(C1-C4 alkyl) or -CONH(C1-C4 alkyl); X is a direct link, O or S; Y and Y1 are each independently O or CH2; and Het is pyridyl, pyrazinyl or thienyl. The compounds are useful as muscarinic receptor antagonists, particularly in the treatment of irritable bowel syndrome.
Patent DE-69029745-D1 (DE)
Inventor: JAMIESON JAMES GERARD
IPC: B65D25/02
Filed: 1990-11-22
Granted: 1997-02-27
Abstract: When dispensing carbonated beverages, particularly beers, it is desirable to obtain a close-knit creamy head. To achieve this a container (1) includes a separate closed hollow insert (5) containing substantially no oxidising gas and means (6) responsive to opening of the container (1) to provide communication between the inside of the insert (5) and beverage (7) contained in the body of the container (1) upon opening it to jet gas from the insert (5) into the beverage (7). The means (6) preferably has the form of a pressure responsive valve. The insert (5) floats on the surface of the beverage (7). <IMAGE>
Patent DE-69034182-D1 (DE)
Inventor: HOUGHTON MICHAEL
IPC: C07K14/18
Filed: 1990-03-16
Granted: 2005-03-03
Abstract: A pharmaceutical composition comprising a hepatitis C virus (HCV) antisense polynucleotide which is selectively hybridizable for the sense strand of the genome of an HCV, wherein the polynucleotide comprises a contiguous sequence of at least 8 nucleotides complementary to the sense strand of the genome of an HCV and a pharmaceutically acceptable excipient, wherein HCV is characterized by:  (i) a positive stranded RNA genome; (ii) said genome comprising an open reading frame (ORF) encoding a polyprotein; and (iii) said polyprotein is encoded by an HCV genome wherein the HCV genome has an homology at the polypeptide level of at least 40% to the 169 amino acid sequence shown in Figure 11.
Patent DE-69105379-D1 (DE)
Inventor: ENAC S A EPONE
IPC: F16F9/30
Filed: 1991-06-21
Granted: 1995-01-12
Abstract: This device employs a viscoelastic material (8) which dissipates the energy of vibration via a coupling means. According to the invention, the viscoelastic material (8) is first arranged and fixed to a support member (7) to form a single removable assembly that can be coupled to the emitter (1) by its own means. The device also comprises a pressure component (9) which, together with the support member (7), clamps the viscoelastic material (8). Application to sound-proofing materials. <IMAGE>
Patent DE-69109857-D1 (DE)
Inventor: BAECKERUD STIG
IPC: C21C1/08
Filed: 1991-02-25
Granted: 1995-06-22
Abstract: PCT No. PCT/SE91/00144 Sec. 371 Date Oct. 22, 1992 Sec. 102(e) Date Oct. 22, 1992 PCT Filed Feb. 25, 1991 PCT Pub. No. W091/13176 PCT Pub. Date Sep. 5, 1991.A melt sample is taken in a sampling vessel which is in thermic equilibrium with the sample quantity prior to solidification commencing, the sampling vessel having been provided with at least one thermoelement and containing a determined and calibrated quantity of inoculating agent based on FeSi and sufficient to produce a maximum inoculating effect. The sample melt is allowed to solidify while temperature changes per unit of time are recorded. The difference between the minimum temperature in the undercooling phase, the maximum temperature in the eutectic reaction phase, and the eutectic equilibrium temperature Te, are determined. To the base melt are added thermodynamically stable particles of the type spinels, oxides or oxysulphides of elements such as magnesium, aluminium, potassium, zirconium, strontium, titanium and rare earth metals when the difference between eutectic equilibrium temperature Te and the minimum temperature in the undercooling phase exceeds 10 DEG  K. and when the difference between Te and the maximum temperature in the eutectic reaction phase exceeds 5 DEG  K. If found suitable, these method steps are repeated until those differences fall beneath 10 DEG  K. and 5 DEG  K., respectively.
Patent DE-69112625-D1 (DE)
Inventor: MAURINUS MARTIN
IPC: G03B17/02
Filed: 1991-06-19
Granted: 1995-10-05
Abstract: A recycleable element includes a means for visually indicating the number of times the element has been recycled whereby the indicating means is updateable each time the element is recycled, up to a maximum recycleable life of the element. Such a recycleable element is particularly useful in a recycleable film pack single-use camera having a built-in electronic flash unit.
Patent DE-69112901-D1 (DE)
Inventor: WITT DONALD REINHOLD
IPC: C08F10/00
Filed: 1991-05-13
Granted: 1995-10-19
Abstract: An improved supported chromium oxide catalyst, a process for preparing the catalyst and a process for polymerizing olefin monomers utilizing the catalyst are provided. In accordance with the preparation process, chromium oxide and a support containing one or more of silica, titania, thoria, alumina, zirconia or aluminophosphates are combined, impregnated with a metal salt and activated. The metal salt is selected from the group consisting of alkali metal salts, alkaline earth metal salts and mixtures thereof.
Patent DE-69122737-D1 (DE)
Inventor: NOTESS PETER C
IPC: H04L12/26
Filed: 1991-07-18
Granted: 1996-11-21
Abstract: Disclosed is a system for collecting and displaying statistical data for a plurality of local area networks (LANs). The data is collected in several remote nodes, each of which is attached to a local area network (103). The data is obtained by using a LAN driver (104) that intercepts all records on the LAN. The records are sent to a collector process (100) where statistics are accumulated into a shared memory area and then transferred to an archiver process (112) in a management node (102). The archiver process writes the statistics to a history file while compressing older data to prevent the file from growing too large. Several display processes run currently in the management node to display the history data. The data is displayed while allowing the user of the system to dynamically select the point in time of the data being displayed, the range of dates and times of the data being displayed as well as the resolution of the graphical screen display. <IMAGE>
Patent DE-69125725-D1 (DE)
Inventor: EVANS ROWLAND FRANK
IPC: B29C45/78
Filed: 1991-11-14
Granted: 1997-05-22
Abstract: A temperature regulating system for a cyclic processor (10), for example an injection moulding machine, the machine having a mould with an internal passageway (17) for receiving temperature regulating fluid such as a coolant. The invention teaches intermittent flow of the temperature regulating fluid, the flow being permitted during certain parts only of the processing cycle, so that for example coolant cannot flow whilst hot melt material is being injected. The systems includes temperature control means (14) and cycle response means, characterised in that the cycle response means initiates operation of the temperature control means at a predetermined stage in a cycle. <IMAGE>
Patent DE-69203133-D1 (DE)
Inventor: HODGE STEVE
IPC: F04D29/60
Filed: 1992-03-27
Granted: 1995-08-03
Abstract: Oil pump manufacture is simplified by providing the pump body with a planar unstepped face and achieving radial location by the provision of a bush 22 (Fig.2) on the pump driven shaft 14, which bush is received in the counterbore 24 of the part journalling the drive shaft 16, i.e. the cylinder block adjacent the end of the drive shaft (crankshaft). <IMAGE>
Patent DE-69213009-D1 (DE)
Inventor: CARR JOHN
IPC: A61M31/00
Filed: 1992-06-11
Granted: 1996-09-26
Abstract: The invention provides a dispensing device comprising a loading dose (first agent delivery means) for short-term and continuous delivery of an agent having a high potency, retained together with a long-term dispensing device (second agent delivery means) capable of a long-term and continuous delivery of agent. The combination of first and second agent delivery means provides a device in which a substantially constant dose of beneficial agent may be delivered to the environment of use over time. A rapid initial delivery of beneficial agent is followed by continuous and prolonged delivery of agent.
Patent DE-69225593-D1 (DE)
Inventor: HOUSEHOLDER WILLIAM R
IPC: B65D25/18
Filed: 1992-06-26
Granted: 1998-06-25
Abstract: A reusable container unit for flowable materials, having enhanced puncture resistance and leak containment characteristics, and being readily handleable by conventional fork lift or the like equipment, comprising a metallic, substantially closed and continuous first wall providing a containment vessel for flowable material, a metallic, substantially closed and continuous second wall providing a protective shell surrounding the vessel and spaced therefrom over at least a major portion of the outer surface thereof to provide protective spacing therebetween, spacer elements positioned between the vessel and shell for substantially maintaining the spacing therebetween, at least one aperture in adjacent portions of each of the vessel and shell and adapted to provide one or more access ports for of the vessel, individual closurer devices for each of the apertures, a tubular wall extending between and connecting the apertures forming each access port to provide a conduit for the flow of materials into and out of the vessel, and at least one base affixed to the shell for stabilizing the container unit in at least one operative position.
Patent DE-69231835-D1 (DE)
Inventor: HADLACZKY GYULA
IPC: C12N5/071
Filed: 1992-09-14
Granted: 2001-06-28
Abstract: Non-human cell lines are disclosed which contain functional centromeres comprising human DNA sequences linked to a dominant marker gene. The centromeres are carried on stable chromosomes which carry no centromeres other than those comprising human DNA sequences. The cell lines can be used to isolate the chromosomes as well as for use in inserting genes into mammalian cells. Methods are taught for generating such cell lines from cell lines carrying dicentric chromosomes. <IMAGE>
Patent DE-69309468-D1 (DE)
Inventor: EBERSOLE RICHARD
IPC: C12Q1/04
Filed: 1993-07-09
Granted: 1997-05-07
Abstract: A composition is provided which is a transducing polymer having from 1 to 20 crosslinks per polymer molecule and selected from the group consisting of amphoteric co- or ter-polymers of pI between 6.2 to 8.0 of acrylic acid, alkyl methacrylate, and N,N-dimethly-aminoethyl methacrylate, the amphoteric co- or ter-polymer immobilized on a surface. Also provided is a method for the preparation of an analyte-responsive polymer immobilized on a surface in which the steps are a. mixing a solution of a crosslinker and the claimed transducing polymer, b. applying the solution of step a to a surface, and c. then curing the polymer to a ratio of from 1 to 20 crosslinks per transducing polymer molecule. Acoustic and optical methods for detecting analtyes are also provided which use an analyte-responsive polymer.
Patent DE-69322708-D1 (DE)
Inventor: SUM PHAIK-ENG
IPC: C07C/
Filed: 1993-05-12
Granted: 1999-02-04
Abstract: The invention provides a novel method for producing compounds of the formula I: <CHEM> wherein X and R are defined in the specifications. The invention also provides a method for making intermediates useful to produce the compounds of formula I. Utilizing a common intermediate, the novel method efficiently produces compounds of the formula I.
Patent DE-69325573-D1 (DE)
Inventor: VARDIMON SLESS HADARA
IPC: A61F13/56
Filed: 1993-11-10
Granted: 1999-08-12
Abstract: Underpants (1) with menses excretion absorbing element as an integral part (2), which do not inflate the woman's figure (9) which is reflected through the clothing as diapers do. These underpants do not have the disadvantage of causing poisoning as tampons do. These underpants do not move out of place or fold in the pudenda, nor do they stick its hair with moist adhesiv and enable menses flowing and staining the clothing as hygienic pads do. These underpants prevent menses from staining the clothing in any pose, also when menses flowing backwards while lying on the back. <IMAGE>
Patent DE-69326243-D1 (DE)
Inventor: MCNEIL KEVIN
IPC: B31F1/07
Filed: 1993-05-27
Granted: 1999-10-07
Abstract: An embossed paper laminate having two laminae. The laminae are embossed so that each embossed site of one lamina is adhesively joined to the nonembossed region of the other lamina. The laminate is made by two close tolerance pattern rolls juxtaposed to form a nip. Each pattern roll has radially extending protuberances which contact the periphery of the other pattern roll intermediate its protuberances. The laminae are fed through the nip in face-to-face relationship and are embossed and adhesively joined to the other lamina by the radially extending protuberances.
Patent DE-69403459-D1 (DE)
Inventor: COOK NIGEL SCOTT
IPC: A61K38/00
Filed: 1994-03-01
Granted: 1997-07-03
Abstract: Peptidomimetics of formula (I), wherein W, Y, R4, R5, Q1 and Q2 are defined in claim 1 are potent thrombin inhibitors.
Patent DE-69405023-D1 (DE)
Inventor: SIEGRIST URS
IPC: C07D253/06
Filed: 1994-02-21
Granted: 1997-09-25
Abstract: A process for the preparation of an aqueous medium of nicotinaldehyde by the catalytic reduction of 3-cyanopyridine under hydrogen in the presence of Raney-nickel.
Patent DE-69415405-D1 (DE)
Inventor: MANEVAL RENE
IPC: D04B15/34
Filed: 1994-06-14
Granted: 1999-02-04
Abstract: Knitted jacquard velvet made on a weft-stitch circular knitting machine, comprising a cylinder (C) equipped with latch needles and a plate (P) equipped with sinkers (13) displaceable between the needles (7) of the cylinder and making it possible to form loops of different heights, characterised in that each row comprises, in addition to a jersey or structured ground thread, various colour threads distributed successively to the needles as a function of the selection of a design to be produced, this being carried out by means of sinkers making it possible to obtain loops of different heights likewise selected as a function of the design, thus making it possible, after a finishing treatment (shearing), to obtain a relief velvet with non-sheared and sheared and multi-coloured loops. <IMAGE>
Patent DE-69416163-D1 (DE)
Inventor: STEPHAN RONAN
IPC: H01G4/008
Filed: 1994-12-01
Granted: 1999-03-04
Abstract: Method for the manufacture of a stacked-type capacitor and/or resistance consisting of alternating dielectric layers and conducting layers. The dielectric layers are deposited by polymerization of the elements derived from the dissociation, by remote nitrogen plasma, of an organo-siliceous or organo-germanium gas. The conducting layers are formed simultaneously by the deposition of a conducting polymer derived from the dissociation, by remote nitrogen plasma, of hydrogen sulphide or sulphur dichloride. The dielectric and conducting layers are deposited on a dielectric substrate placed on the surface of a rotating drum, the rotation being such that the same portion of dielectric substrate is successively opposite at least one dielectric deposition device and at least one conducting polymer deposition device, each dielectric or conducting deposition being preceded by masking of the areas where no layer is to be deposited.
Patent DE-69428590-D1 (DE)
Inventor: SEYBOLD JOHN L C
IPC: G06V30/32
Filed: 1994-11-10
Granted: 2001-11-15
Abstract: In a handwriting recognition process, a list of candidate recognized words is identified (202) as a function of both comparison of dictionary entries to various combinations of recognized character combinations, and through a most likely character string and most likely string of digits analysis as developed without reference to the dictionary. The process selects (301) a word from the list and presents (302) this word to the user. The user then has the option of displaying (303) this list. When displaying the list, candidate words developed with reference to the dictionary are displayed in segregated manner from the most likely character string words and the most likely string of digits. The user can charge the selected word by choosing from the list, or edit the selected word. When the user selects the most likely character string as the correct representation of the handwritten input to be recognized, the process automatically updates (310) the dictionary to include the most likely character string The same process can occur when the user selects the most likely string of digits.
Patent DE-69432662-D1 (DE)
Inventor: KRAUTSCHNEIDER WOLFGANG
IPC: H01L27/02
Filed: 1994-02-03
Granted: 2003-06-18
Abstract: In order to restrict the voltage across the gate oxide of an input pass-through transistor which operates as an input signal source to a MOS inverter, an MOS transistor wired as a MOS diode is connected between the source and gate electrode of the pass-through transistor. The diode connected transistor allows the use of a thin oxide device for the pass-through transistor which enables a high transconductance device to be employed while restricting the voltage across the gate oxide of the pass-through transistor to an acceptable value. <IMAGE>
Patent DE-69433111-D1 (DE)
Inventor: O'BRIEN W
IPC: G01N29/00
Filed: 1994-06-07
Granted: 2003-10-09
Abstract: PCT No. PCT/AU94/00307 Sec. 371 Date Aug. 31, 1995 Sec. 102(e) Date Aug. 31, 1995 PCT Filed Jun. 7, 1994 PCT Pub. No. WO94/29694 PCT Pub. Date Dec. 22, 1994A method and device is disclosed for determining the distribution of charge and size in a colloidal system. The arrangement disclosed is adapted to measure these characteristics in an inhomogeneous colloid. A colloid is subjected to a steady or slowly varying force which moves the particles at a rate that depends on their radius or charge and thereby sets up spatial inhomogeneities in the suspension, and to either a unsteady mechanical force or an unsteady electrical force, and the resulting electrical or acoustic effects sensed. Monitoring these characteristics over time and subsequent calculation allows the determination of charge and size distribution, for each species present.
Patent DE-69433945-D1 (DE)
Inventor: SCRIVEN ERIC F V
IPC: C08F2/06
Filed: 1994-10-25
Granted: 2004-09-16
Abstract: Described are preferred processes for producing linear polyvinylpyridines. The processes involve the use of hydrogen peroxide to initiate polymerization of vinylpyridine monomers in an aqueous solvent. Processes of the invention provide good reaction rates and conversions, and are particularly advantageous in achieving control of the MW's of the final product polymers.
Patent DE-69509039-D1 (DE)
Inventor: MANNING KEVIN
IPC: B07C5/10
Filed: 1995-05-25
Granted: 1999-05-20
Abstract: PCT No. PCT/GB95/01198 Sec. 371 Date Dec. 27, 1995 Sec. 102(e) Date Dec. 27, 1995 PCT Filed May 25, 1995 PCT Pub. No. WO95/33181 PCT Pub. Date Dec. 7, 1995An apparatus for the measurement of the curvature of a surface is provided. The apparatus has at least one source of electromagnetic radiation, a two-dimensional electromagnetic radiation detector and a lens, positioned to focus source radiation reflected from the surface onto the detector. A beam splitter is positioned between the detector and the surface via which radiation from the source is directed onto the surface. A calculating device is provided for calculating the measurement from signals detected by the detector. A scanning device is provided which causes a beam of radiation from the source to be scanned across the surface, thereby producing a multiplicity of beams which are reflected from the surface via the lens where a reflected angle of each beam is transformed in a physical displacement on the detector. The scanning device may be a scanning mirror prism or a light shutter used in combination with a further lens.
Patent DE-69516605-D1 (DE)
Inventor: YAEGASHI TAKASHI
IPC: C07D209/00
Filed: 1995-09-05
Granted: 2000-06-08
Abstract: New camptothecin derivatives of the general formula (1), preparations thereof and antitumor agents comprising the same, <CHEM> wherein R<1> represents a hydrogen atom or a C1-C6 alkyl group, R<2> represents a hydrogen or a C1-C6 alkoxy group, R<3> represents a hydrogen or halogen atom or a C1-C6 alkyl, C1-C6 alkoxy, hydroxyl, C2-C6 acyloxy or methoxyethoxymethoxy group, R<4> represents a hydrogen or halogen atom, and R<5> represents a C1-C6 alkyl, C3-C6 unsaturated alkyl, alkylthioalkyl, alkoxyalkyl, pyridyl or substituted phenyl group, with the proviso that all of the R<2>, R<3> and R<4> substituents should not be a hydrogen atom.
Patent DE-69522275-D1 (DE)
Inventor: SASSI IVES
IPC: E01C21/00
Filed: 1995-06-12
Granted: 2001-09-27
Abstract: The implement is intended to be coupled to a motor-driven towing vehicle and comprises a roller-cutter (10) of substantially horizontal axis, to the cylindrical surface of which there is fixed a plurality of tools (11) able to crush and shift the ground (A) to be treated; means for rotating said roller-cutter about its axis are also provided, as are means for supporting the roller-cutter (10) arranged with its axis substantially perpendicular to or possibly inclined to the direction of advancement and for maintaining the lower surface of the roller-cutter (10) at the required depth below the surface of the ground to be treated; finally, means are provided for distributing the material crushed by the roller-cutter (10) in such a manner as to fill any recesses and flatten any projections. <MATH>
Patent DE-69531420-D1 (DE)
Inventor: NEILL PAUL
IPC: A61K8/41
Filed: 1995-02-08
Granted: 2003-09-11
Abstract: A mild permanent wave reducing agent-containing composition includes two ionic compounds, one cationic and the other anionic, that complex in solution over a molar ratio of cationic compound to anionic compound in the range of 1:1.2 to 1.2:1. The cationic compound, in solution, forms a cation of formula I or formula II, or a mixture of two or more thereof; <CHEM>   <CHEM> wherein R1, R2, R3, R5, R6 and R7, same or different, are H, an alkyl group or hydroxyalkyl group having 1 to 5 carbon atoms; and R4 is OH, -OR8 or -NR9R10, wherein R8, R9 and R10, same or different, are H, an alkyl group or hydroxyalkyl group having 1 to 4 carbon atoms, A is an alkylene group having 1 to 5 carbon atoms; and B is O or S; and the anionic compound. in solution, forms an anion of formula III: <CHEM> wherein A is nonexistent or an alkylene group having 1 to 5 carbon atoms, and Y is H, OH, NH2 or <CHEM> wherein R12 is an alkyl group having 1 to 5 carbon atoms. Examples of cationic compounds include thiocholine, choline, cysteineamide, cysteamine, and combinations thereof. Examples of anionic compounds include cysteine, N-acetylcysteine, thioglycolic acid or its salts, and combinations thereof.
Patent DE-69532122-D1 (DE)
Inventor: BERKA M
IPC: C12N1/15
Filed: 1995-06-23
Granted: 2003-12-18
Abstract: Novel methods are disclosed for the enhanced expression and secretion of lactase from filamentous fungi. Specifically the novel processes cause enhanced production of lactase from an Aspergillus and preferably enhanced production of A. oryzae lactase from A. oryzae host strains transformed with necessary DNA. Also described are the DNA sequence encoding the lactase gene from A. oryzae and the deduced amino acid sequence of the lactase therefrom.