baber/WOPTO huggingface dataset:
Patent EP-0284547-B1 (EP)
Inventor: KLAR ULRICH DR
IPC: C07C405/00
Filed: 1988-03-11
Granted: 1994-01-05
Abstract: PCT No. PCT/DE88/00151 Sec. 371 Date Nov. 23, 1988 Sec. 102(e) Date Nov. 23, 1988 PCT Filed Mar. 11, 1988 PCT Pub. No. WO88/07037 PCT Pub. Date Sep. 22, 1988.The invention relates to 6-oxo-prostaglandin E1 derivatives of formula I,   <IMAGE> (I)  in which R1 means the radical COOR2 with R2 meaning a hydrogen atom, C1-C10 alkyl, a C5-C6 cycloalkyl or a C6-C10 aryl group or a heterocyclic radical, or the radical CONHSO2 R5 as C1-10 alkyl, C5-6 cycloalkyl or C6-10 aryl, A means an E-configuration CH=CH or a -C=C group, W means a free or functionally modified hydroxymethylene group or a free or functionally modified group, and the OH group in each case can be in the alpha or beta position, D means a straight-chain or branched-chain alkylene group with 1-5 C atoms, E means a -C=C group or a C2-C4 alkenylene group, R3 means C1-C10 alkyl, C3-C10 cycloalkyl or an optionally substituted C6-C10 aryl group or a heterocyclic group, R4 means a free or functionally modified hydroxy group, and if R2 means a hydrogen atom, its salts with physiologically compatible bases as well as alpha, beta or gamma cyclodextrin clathrates of the compounds of formula I, process for their production and their pharmaceutical use.
Patent EP-0417069-B1 (EP)
IPC: B01D39/14
Filed: 1988-01-05
Granted: 1992-11-25
Abstract: Des milieux filtrants consistent en des nappes formables appliquées par jet d'air et comprenant une résine liante thermoplastique ou thermodurcissable et un mélange de fibres comportant des fibres grossières, telles que des fibres cellulosiques et artificielles, ayant un diamètre d'au moins 20 microns, et des fibres de verre ou d'autres fibres ayant un diamètre inférieur à environ 3 microns.
Patent EP-0309558-B1 (EP)
Inventor: KAEMPFER RAYMOND
IPC: C12Q1/6806
Filed: 1988-04-05
Granted: 1994-11-02
Abstract: A method allowing accurate and sensitive detection of a transient expression of bioregulatory genes in microcultures of eukaryotic cells. The method comprises the steps of (a) isolating and culturing the cells under conditions inducing the expression of at least one of the said genes, (b) lysing the cells with guanidinium hydrochloride, (c) selectively precipitating ribonucleic acid by adding to the homogenised cell preparation a sodium or potassium acetate solution followed by absolute ethanol, (d) recovery and blotting RNA onto a support matrix, (e) hybridizing recovered and blotted RNA with a labelled riboprobe specific for at least one of said genes, and (f) quantitatively determining the extent of binding of the labelled riboprobe to the blotted RNA. The use of varying induction processes on separate aliquots of a cell sample allows an understanding to be obtained of the dynamic functionality of the said gene or genes in the cells.
Patent EP-0332704-B1 (EP)
Inventor: KANEKO TAKEHIRA ODAWARA RESEAR
IPC: C08J5/12
Filed: 1988-07-29
Granted: 1994-12-21
Abstract: A process for producing a conductive polymer film, which comprises preparing a homogeneous, stable precursor solution containing an aromatic compound such as pyrrole, thiophene, aromatic amine or a derivative thereof, an oxidizing agent and a solvent and not immediately causing polymerization, and casting the precursor solution onto a base material to obtain uniform and touch conductive polymer film upon removal of the solvent by evaporation.
Patent EP-0328932-B1 (EP)
Title: Body fluid sample collection tube assembly
IPC: B01L3/14
Filed: 1989-02-01
Granted: 1993-07-14
Abstract: An assembly (10) is provided for receiving, maintaining and storing blood samples taken from individuals some of whom may have a disease which can contaminate anyone handling the sample. The assembly (10) includes a glass tube (14) which may be evacuated for facilitating and receiving a blood sample coaxially retained within a plastic tube (12) which retains the sample and the general integrity of the assembly (10) in the event that the glass tube (14) cracks or breaks during handling. Thus, the glass tube (14) maintains a long shelf-life for the evacuated tube, and does not react adversely or interfere with blood chemistries, while the outer plastic sleeve (12) protects the user from broken glass and/or contamination. A special interlock ring (18) holds the glass tube (14) coaxially in place relative to the plastic tube (12).
Patent EP-0407650-B1 (EP)
IPC: A61F2/66
Filed: 1989-07-20
Granted: 1993-10-06
Abstract: Within its plantar area, the artificial foot for a leg prosthesis is provided with a plate-shaped reinforcing member (10) embedded in the molded foot part. The member 10 includes two superimposed upper and lower leaf springs (15a, 15b) possessing different lengths, between which a carbon fiber-reinforced plastic leaf spring (18) is disposed extending. The latter extends into the ball of the foot area and is offset at the front end. Sliding inserts (17a, 17b) of polyethylene and each face of the plastic leaf spring and between the upper and lower leaf springs produce a constant metatarsal elasticity even during continuous stress.
Patent EP-0373335-B1 (EP)
Inventor: HEINZEL-WIELAND REGINA DR
IPC: C12N15/15
Filed: 1989-10-31
Granted: 1997-12-10
Abstract: The invention relates to serine protease inhibitor proteins, medicaments containing them, DNA sequences coding for these proteins and methods for producing these proteins, medicaments and DNA sequences. These proteins correspond to the formula <IMAGE> or sections thereof which comprise at least the sequence of positions 53-101, in which W is tyrosine or glutamic acid, X1, X2 and X3 are identical or different and each of these radicals is methionine or leucine, it also being possible for X3 to be phenylalanine, Y is proline or arginine, and Z is leucine or, if W is tyrosine and X1, X2 and X3 are leucine, is also isoleucine, and fusion proteins of these serine protease inhibitor proteins. The proteins are particularly distinguished by a strong inhibitory action against human leukocyte elastase and pronounced stability to oxidative breakdown. DNA sequences which code for the serine prolease inhibitor proteins and the expression of these proteins in suitable host organisms by means of various vectors, and the isolation of these proteins in pure biologically active form, and medicaments containing these products, are described. <IMAGE> (Oligonucleotid = oligonucleotide> Figure 1a: DNA oligonucleotides D11, D12, D13, D11a, D12a and D13a (listed in the 3'->5' direction of synthesis) which are used in the synthesis of the DNA sequence "ALP gene 230" (Figure 2a). <IMAGE> Figure 1b: DNA oligonucleotides D21, D22, D23, D21a, D22a and D23a (listed in the 3'->5' direction of synthesis) which are used in the synthesis of the DNA sequence "ALP gene 230" (Figure 2a). <IMAGE> Figure 1c: DNA oligonucleotides D24, D25, D24a and D25a (listed in the 3'->5' direction of synthesis) which are used in the synthesis of the DNA sequence "ALP gene 240" (Figure 2b) commencing from the DNA sequence ALP gene 230.
Patent EP-0336483-B1 (EP)
Inventor: KOENHEN DIRK MARINUS
IPC: B01L3/00
Filed: 1989-03-23
Granted: 1994-06-29
Abstract: A process and device for the separation of a body fluid from particulate materials in said fluid to be used for a chemical analysis of the components present therein. Said process and device are in particular suitable for the separation of plasma from whole blood. Furthermore the present invention relates to a testing kit for the above mentioned separation and analysis purposes. Because of the simplicity of the present process and device as well as the testing kit a routine examination may be carried out not only in clinical laboratories but also by general practitioners.
Patent EP-0342026-B1 (EP)
Inventor: FISHER HAROLD MANLY
IPC: C08J9/00
Filed: 1989-05-11
Granted: 1995-10-18
Abstract: Disclosed are a process for forming an open-celled microporous membrane (e.g., in film or fiber form) and a novel microporous membrane formed thereby. The process generally includes sequential cold and hot stretching operations, whereby the cold stretching operation is preferably accomplished in a plurality of discrete cold stretching steps. In this regard, the total cold stretch extension is of greater than about 30 percent, and advantageously greater than about 40 percent based upon the initial unstretched length of the nonporous precursor, with this total cold stretch ratio being distributed among a plurality of discrete cold stretching steps. The novel membranes of this invention are characterized by decreased pore sizes and increased pore densities. For example, the membranes of this invention will have an average pore radius as determined by mercury porosimetry of less than about .040 micron. The membranes of this invention, moreover, exhibit a distinctive "bluish" color hue (i.e., a Macbeth Coloreye TM  b* value of less than about -10 as determined by placing a single ply sample of the membrane against a black background).
Patent EP-0343986-B1 (EP)
Inventor: VICARI RICHARD
IPC: C08F12/24
Filed: 1989-05-25
Granted: 1996-02-28
Abstract: Poly(4-hydroxystyrene) is prepared by aqueous suspension polymerization of 4-acetoxystyrene monomer followed by hydrolysis with ammonium hydroxide.
Patent EP-0350313-B1 (EP)
IPC: F16H1/16
Filed: 1989-07-06
Granted: 1992-09-09
Abstract: The platform includes: (a) a stage (2) having two opposite end portions (3) for conveying objects thereon; (b) a pair of elongated arms (11) attached to the respect end portions of the stage, slidable and rotatable with respective to the stage (2) in a horizontal plane; (c) a plurality of holding means (14, 15) installed in the arms, the holding means being adapted to hold hanging means of the structure, to hang therefrom; (d) driving means (31) to slide and rotate the elongated arms (11) with respect to the stage (2) and the hanging means (14, 15); and (e) a control means for sliding and rotating the driving means (31) and for holding and releasing the holding means (14, 15), whereby the stage (12) is conveyed with respect to the structure.
Patent EP-0364130-B1 (EP)
Inventor: BECKMANN ROBERT JOHN
IPC: C12N15/52
Filed: 1989-09-27
Granted: 1995-08-02
Abstract: Gene sequences are provided encoding tylosin biosynthetic gene products. In particular, recombinant DNA vectors comprising DNA sequences encoding the tylA, tylB, tylI and tylG activities of Streptomyces fradiae are provided. Also provided are host cells transformed with the noted vectors and a method for increasing the tylosin-producing ability of a tylosin-producing organism.
Patent EP-0341100-B1 (EP)
Inventor: MIZUNO DEN ICHI
IPC: C12N15/62
Filed: 1989-04-03
Granted: 1994-03-16
Abstract: Anti-tumor polypeptides represented by the amino acid sequence: (The amino acid sequence of TH beta 4)-Asp-Pro-x-(the amino acid sequence corresponding to the base sequence constructed by linking guanine with the beginning of the base sequence of the fourth exon of TNF- alpha  ) wherein X is a part of the linkage or represents any of the following amino acid sequences:   1) Val-Ser-Ser-Ser-Arg-Thr-Pro-Ser-Asp-Lys-Pro-Val-Ala-His-Val-Val;   2) Val-Arg-Ser-Ser-Ser-Arg-Thr-Pro-Ser-Asp-Lys-Pro-Val-Ala-His-Val-Val; 3) Val-Lys-Ser-Cys-Thr-Arg-Thr-Pro-Ser-Arg-Lys-Pro-Val-Ala-His-Val-Val; 4) Val-Arg-Ser-Ser-Thr-Arg-Thr-Pro-Ser-Arg-Lys-Pro-Val-Ala-His-Val-Val; and 5) Val-Arg-Ser-Cys-Thr-Arg-Thr-Pro-Ser-Arg-Lys-Pro-Val-Ala-His-Val-Val. and, novel DNAs coding them, processes for their preparation, and anti-tumor agents comprising them are disclosed.
Patent EP-0383848-B1 (EP)
Inventor: SCHUSTER RICHARD LEE
IPC: B65D71/20
Filed: 1989-03-24
Granted: 1994-05-18
Abstract: A wrap-around carton with overlapping flaps overlying a substantially flat surface of the packaged article. A tab on the outer flap extends into a slot in the inner flap, with shoulders formed from a slot in the outer flap engaging the edge of the slot in the inner flap to mechanically connect the flaps together. In addition, a tab on the inner flap is inserted into the slot in the outer flap, whereby the inner flap tab urges the shoulders down so as to hold the locking mechanism in place and the edge of the slot in the outer flap holds the inner flap tab in place.
Patent EP-0422054-B1 (EP)
IPC: C10K1/12
Filed: 1989-06-21
Granted: 1992-03-18
Abstract: La désulfuration du gaz de fours à coke dans un laveur à H2S (1) ou un laveur à NH3 (51), le gaz brut ayant le même degré de purification, se fait de manière beaucoup plus rationnelle et produit des vapeurs de NH3 nettement plus adaptées au traitement ultérieur si l'on utilise une colonne de rectification (72) supplémentaire, si les vapeurs de NH3 sont redirigées (82) vers la partie centrale du laveur à H2S (1) et si l'on a recours à de l'eau ammoniacale concentrée (78) dans la partie centrale du désacidificateur (15).
Patent EP-0383879-B1 (EP)
IPC: B05B7/18
Filed: 1989-07-27
Granted: 1993-04-14
Abstract: Die Erfindung betrifft eine Drahtpistole mit einer Vorschubeinrichtung für den Draht mit einem von einem Motor angetriebenen Antriebsrad für den Draht und einer den Draht gegen das Antriebsrad drückenden Gegenrolle, sowie mit einer Einrichtung für die Regelung der Vorschubgeschwindigkeit des Drahtes. Bekannte Drahtpistolen dieser Art haben den Nachteil, daß die Regelung der Drahtvorschubgeschwindigkeit nicht genau genug erfolgt, und sich beim Flammspritzen kein ausreichend gleichmäßiger Ausstoß des zu verspritzenden Drahtmaterials ergibt. Es ist die Aufgabe der Erfindung, eine Drahtpistole mit genauer Regelung der Vorschubgeschwindigkeit zu schaffen. Diese Aufgabe wird dadurch gelöst, daß ein den Draht abtastendes Meßrad für die Messung des Istwerts der Vorschubgeschwindigkeit vorgesehen ist, und daß die Einrichtung zur Regelung der Vorschubgeschwindigkeit des Drahtes eine Vorrichtung zur Änderung des Anpreßdrucks der Gegenrolle in Abhängigkeit von einer durch Einwirkung der Regelungseinrichtung auf den Motorantrieb nicht einregelbaren Sollwertabweichung umfaßt.
Patent EP-0406348-B1 (EP)
Inventor: JOHANSSON HARRY
IPC: B03C3/45
Filed: 1989-11-02
Granted: 1994-01-12
Abstract: L'invention concerne un agencement dans un filtre électrostatique liquide (1) destiné à purifier un gaz chargé d'humidité et de poussière. Le filtre électrostatique liquide (1) comprend une unité de refroidissement à condensation (21) qui est intégrée à l'élément de précipitation (20) du filtre électrostatique liquide. Une pluralité d'électrodes d'émission (4) sont situées à l'intérieur des électrodes collectrices (5) et les électrodes collectrices traversent le dispositif de refroidissement (21). Des moyens en forme de tuyaux de distribution (50, 60) sont disposés à l'intérieur des extrémités supérieure et inférieure de l'élément de précipitation, de façon à créer une répartition uniforme du milieu de refroidissement (23) sur les surfaces externes des électrodes collectrices (5), le gaz s'écoulant vers l'avant à l'intérieur des électrodes collectrices (5). Cette distribution uniforme du milieu de refroidissement a pour conséquence une réduction du taux de corrosion sur les surfaces internes des électrodes collectrices (5), suite à la formation de condensation sur ces surfaces et suite à la température uniforme et basse des électrodes collectrices et également suite à une concentration plus faible de substances corrosives à l'intérieur du condensat. Cette structure présente des avantages d'ordre technique et économique et permet également de fabriquer des électrodes collectrices en un acier à teneur rélativement basse en alliage.
Patent EP-0383037-B1 (EP)
Inventor: VITS HILMAR
IPC: F26B13/20
Filed: 1990-01-18
Granted: 1993-12-15
Abstract: The invention relates to an apparatus for the floatable guiding of webs of material by air blown against the web. The apparatus comprises blowing boxes 2-6 disposed offset in relation to one another above and below the web 1 of material. Each blowing box 2-6 has two opposite rows of blowing apertures 21 whose blowing direction encloses an acute angle a2 with a deflecting surface 25, 26 which adjoins the edge of the blowing aperture 21 remote from the web 1 of material. The deflecting surface 25 also encloses an acute angle a3 with the web 1 of material. The two acute angles a2, a3 are so selected that the air blown out of the blowing apertures 21 is guided away the deflecting surfaces 25 and against the web 1 of material, where it spreads out in the form of a source flow 30. In this way both a strong air cushion supporting the web 1 of the material is obtained and also a high heat transfer at the web 1 of material and a clearly-defined flow of the blown air from the air cushion.
Patent EP-0389783-B1 (EP)
Title: Fastener assembly with sealing grommet
IPC: F16B41/00
Filed: 1990-02-20
Granted: 1993-03-17
Abstract: A threaded fastener assembly (10) which includes a threaded fastener (12) over which is securely held an axially movable washer (14) with a resilient grommet fitted thereover (16). The threaded fastener assembly (10) is adapted to be preassembled in a first apertured work piece (50) such as a rocker arm cover which is to be mounted on a second apertured work piece (52) such as an engine block. The threaded fastener assembly (10) is retainable within the first apertured work piece (50) while holding the fastener in a freely axially movable configuration which permits the fastener to be moved into an elevated position to prevent the fastener from projecting through the bottom surface of the work piece, thus preventing interference with other surfaces and the structure provides seals for preventing fluid from leaking through the apertures.
Patent EP-0400356-B1 (EP)
Inventor: FISCHER KLAUS DR
IPC: A01N43/90
Filed: 1990-05-07
Granted: 1994-08-10
Abstract: Sulphonamides of the general formula I <IMAGE>  in which the substituents and indices have the following meanings:  R<1> represents hydrogen or C1-C4-alkyl,  R<2> represents hydrogen, optionally substituted C1-C6-alkyl; C3-C4-alkenyl; C3-C4-alkynyl or optionally substituted saturated or monounsaturated 5- to 7-membered heteroaryl; R<3> and R<4> represent halogen; optionally substituted C1-C4-alkoxy, C1-C4- alkylthio, C2-C6-alkenyl, C2-C6-alkenyloxy, C2-C6-alkenylthio, C2-C6- alkynyl, C2-C6-alkynyloxy, C2-C6-alkynylthio, C3-C6-cycloalkyl, C3-C6- cycloalkylthio, C5-C6-cycloalkenyl, C3-C6-cycloalkoxy, C5-C6- cycloalkenyloxy, C5-C6-cycloalkenylthio, phenyl, phenoxy, phenylthio, benzyl, benzyloxy or benzylthio;  the groups mentioned under R<2> or  NR<7>R<8> in which R<7> and R<8> represent hydrogen, C1-C6-alkyl, C3-C6-alkenyl, C3-C6-alkynyl, C3-C6-cycloalkyl, C5-C6-cycloalkenyl, optionally substituted phenyl and/or benzyl, or represent optionally substituted C4-C6-alkylene which can be interrupted by oxygen, sulphur or nitrogen; X represents nitrogen or =CR<5>- in which R<5> represents one of the radicals R<3>,  n represents 0 or 1 and A represents optionally substituted aryl with one or two rings, containing one to two nitrogen, oxygen and/or sulphur atom(s), and their agriculturally useful salts, and herbicidal and plant- growth-regulating compositions containing them.
Patent EP-0432372-B1 (EP)
Inventor: FILSER HELMUT
IPC: A47B57/42
Filed: 1990-09-03
Granted: 1996-05-15
Abstract: The cantilever shelf serves for the accommodation and storage of products, in particular made of wood, metal and the like, in elongate, plate-type or similar shape, and of pallets or similar crates provided with articles. The shelf consists of vertically arranged uprights (1), in particular in the form of profiles, into which horizontally projecting cantilevers (2) can be inserted detachably. For this purpose, the uprights (1) have at least one contact surface (3) which extends in the longitudinal direction of said uprights, is provided with openings (4) arranged at regular intervals, and on which the cantilever (2) rests with a supporting surface (5). The cantilever (2) has at least one claw (6) which projects over its supporting surface (5), is essentially of right-angled construction, whose free end (6.1) extends approximately parallel to the supporting surface (5), and which extends through one of the openings (4) when the cantilever (2) is inserted in the upright (1), thereby gripping with its free end (6.1) behind the edge of the opening (4). Seen in the longitudinal direction of the upright (1), the openings (4) have an elongate shape, the length of which corresponds essentially to the length of the free end (6.1) of the claw (6) on the cantilever (2). Projecting from the supporting surface (5) of the cantilever (2) is at least one pin (7) provided for engagement in an adjacent opening (4), the spacing between the claw (6) and the pin (7) being such that, when the cantilever (2) is inserted, the edges of the openings (4) form stops on both sides for the claw (6) and the pin (7), with the result that the displaceability of the cantilever (2) in the longitudinal direction of the upright (1) is blocked. <IMAGE>
Patent EP-0417793-B1 (EP)
Title: Method for packaging solid foodstuffs and packaging thereof
IPC: B65B25/16
Filed: 1990-09-13
Granted: 1993-09-22
Abstract: The invention relates to a method of packaging solid foodstuffs for improved shelf life and quality, utilising a reaction between the components glucose and oxidase, in particular for packaging baked products, the first reaction component, if appropriate fixed on a separate mechanical carrier, being first introduced into the packaging and the second component being added only just before packaging, the packaging preferably being carried out additionally in the presence of an inert gas, especially nitrogen or carbon dioxide, as a protective gas. The invention also relates to a packaging material which is provided for receiving a reaction system consisting of the components glucose and oxidase, one component of the reaction system being present as a layer on a carrier.
Patent EP-0427176-B1 (EP)
Inventor: GONZALES ENTERRIA D JOSE JAVIE
IPC: F03B7/00
Filed: 1990-11-05
Granted: 1995-02-01
Abstract: This machine consists of an impeller formed by a right prism with a minimum weight/volume ratio and which has an irregular hexagonal section, three sides of which are bigger than the other three, and with said hexagon's vertexes belonging to a single circumference. The second body of said machine is formed by an open cylindrical chamber, concentric to the impeller, with an angle of approximately 83 degrees. Its basic characteristic is its high performance in obtaining energy produced by minimum height waterfalls.
Patent EP-0399622-B1 (EP)
IPC: A01B29/00
Filed: 1990-05-23
Granted: 1993-01-13
Abstract: The invention relates to a soil working device, comprising a substantially cylindrical soil working member (7), which is mounted between two main supporting arms (2) for rotation about a substantially horizontal axis and is axially composed of a number of sections which are mutually connected and connected with two shaft end sections (23) journalled in said main supporting arms (2) respectively through couplings of the universal type, the coupling between each two sections being supported by an auxiliary supporting arm (27) which extends into the travelling direction and pivotally engages a connecting bar (31) extending between said main supporting arms (2) parallel to and in front of said soil working member. According to the invention both the axis (10) of the soil working member and the connecting bar (31) are located at substantially the same level, so that the auxiliary supporting arms (27) are a substantially horizontal position and the rotational axis of the working member will be kept - as seen in the horizontal plane, substantially straight.