baber/WOPTO huggingface dataset:
Patent EA-023574-B1 (EA)
Title: 6-CYCLOBUTYL-1,5-DIHYDROPYRAZOLO[3,4-d]PYRIMIDIN-4-ONE DERIVATIVES AND THEIR USE AS PDE9A INHIBITORS
Inventor: HEINE MIKLAS
IPC: C07D487/04
Filed: 2012-02-13
Abstract: The invention relates to novel pyrazolopyrimidinones according to formula (I)wherein Ris a pyridyl or pyrimidinyl group and D is optionally substituted cyclopentyl, cyclohexyl, tetrahydrofuranyl, tetrahydropyranyl or 2-, 3-or 4-pyridyl. The new compounds are for use as the active entity of medicaments or for the manufacture of medicaments respectively, in particular medicaments for the treatment of conditions concerning deficits in perception, concentration, learning or memory. Such conditions may for example be associated with Alzheimer's disease, schizophrenia and other diseases. The new compounds are also for example for the manufacture of medicaments and/or for use in the treatment of these diseases, in particular for cognitive impairment associated with such disease. The compounds of the invention show PDE9 inhibiting properties.
Patent EA-025401-B1 (EA)
Title: Attachment system for attaching an insert to a glass panel, attachment element for said system and method for manufacturing said system
Inventor: GRANDGIRARD BASTIEN
IPC: B60J10/00
Filed: 2011-09-28
Abstract: The present invention relates to a glass panel (1) including a vitreous element (2), at least a profiled joint portion (3), at least one insert (4) such as a bezel, and at least one attachment element (5) for attaching said insert (4) to said profiled joint portion (3), characterized in that the attachment element (5) comprises a sole plate (7) having a longitudinal axis, wherein the sole plate is at least partially overmolded into the profiled joint portion (3) and has at least two flanges (8, 8') that are located outside said profiled joint portion (3) in order to attach said insert (4) to said attachment element (5), said flanges being longitudinally offset.
Patent EA-025569-B1 (EA)
Title: Compositions and methods for modulating fxr
Inventor: TULLY DAVID C
IPC: C07D487/04
Filed: 2011-11-30
Abstract: The present invention relates to compounds of Formulas I and II, pharmaceutically acceptable salts thereof:The invention relates to a pharmaceutical composition comprising a therapeutically effective amount of the compounds of Formulas I and II or a pharmaceutically acceptable salt thereof for treating a farnesoiod X receptor mediated condition and the use of the above mentioned compounds for treating a farnesoiod X receptor (FXR) mediated condition. A process for the production of a compound of Formula I or a pharmaceutically acceptable salt thereof, comprising reacting a compound of Formula II with a compound III Y-Z-R, is disclosed herein. The meanings of radicals for the compounds I, II and III are defined in the claims.
Patent EA-026024-B1 (EA)
Title: Method for remote determination of mass concentrations of atmospheric aerosol fractions
Inventor: LYSENKO SERGEY ALEXANDROVICH
IPC: G01N15/06
Filed: 2014-07-01
Abstract: The invention is related to the field of environment protection and analytical instrument engineering. The objective of the invention is improvement of accuracy in remote determination of concentrations PMand PM, broadening of functional capabilities of the method by determining PMand total mass concentration of industrial and city aerosols. The objective is attained by that a known method of remote determining mass concentration comprises the following additional steps: radiation at λ=2,13 μm is sent and the corresponding signal P(r, λ) is registered, on the basis of signals P(r, λ), a spatial profile of aerosol attenuation factor ε(λ) at λ=0.355, 0.532, 1.064, 2.13 μm is determined, linearly independent components of spectral coefficient ε(λ) for every point of the path are calculated as projections of ε(λ) on the space of eigenvectors of the covariance matrix ε(λ), and concentrations PM, PM, PMand total mass concentration of aerosol are determined on the basis of their regression links with linearly independent components ε(λ).
Patent EA-030814-B1 (EA)
Title: Anthelmintic compounds, compositions and methods of use thereof
Inventor: MENG CHARLES Q
IPC: C07D417/12
Filed: 2013-11-19
Abstract: The present invention relates to novel anthelmintic compounds of formula (IA-1)Variables in formula (IA-1) are as defined herein. The invention also provides for veterinary compositions comprising the anthelmintic compounds of the invention, and their uses for the treatment and prevention of parasitic infections in animals.
Patent EA-037909-B1 (EA)
Title: Immunogenic compositions and vaccines derived from bacterial surface receptor proteins
Inventor: SCHRYVERS ANTHONY B
IPC: C12N15/63
Filed: 2014-12-01
Abstract: The invention provides immunogenic compositions comprising a polypeptide comprising a C-lobe domain or an N-lobe domain of a HIBP (host iron binding protein) surface receptor protein obtainable from or obtained from a Gram-negative bacterial species. The HIBP surface receptor proteins have been modified in such a manner that they are unable to bind host iron binding protein. Methods of making and using these immunogenic positions to prepare animal and human vaccines are also provided.
Patent EA-036228-B1 (EA)
Title: Refractory tube wall lining for an incinerator
Inventor: VAN DER HOEFF JOSEPH ADRIANUS MARIA
IPC: F23M5/08
Filed: 2015-06-04
Abstract: Refractory lining of a tube wall (2) for an incinerator, comprising at least four refractory tiles (3) of ceramic material, which are arranged next to and above one another, wherein the tiles at their rear side, which is facing the tube wall (2), are provided with a vertical insertion channel (10) for mounting the tiles upon the holders (7) of the tube wall, wherein a free space (11) is formed between the tiles (3) and the tube wall (2), which space is filled with a curable pouring compound, and wherein a spacer (20) is provided adjacent to four mutually adjoining edges (12) of the at least four refractory tiles (3). Alternative embodiments are characterized by the use of a head bolt, and/or a wedge element (50) and/or a clip-element (60).
Patent EA-034635-B1 (EA)
Title: Method of two-stage surgical treatment of newborns with large-size omphalocele
Inventor: ZAPOLYANSKY ANDREY VALENTINOVICH
IPC: A61B17/00
Filed: 2017-09-28
Abstract: The invention relates to medicine, in particular to pediatric surgery, and can be used for surgical treatment of congenital malformation of the anterior abdominal wall - large omphalocele. Omphalocele is a ventral defect in the umbilical ring and is one of the most common congenital malformations of the anterior abdominal wall in newborns. A method is claimed of two-stage surgical treatment of newborns with large omphalocele, in which a defect is closed with skin flaps during the first operation and loops are sutured to muscular-aponeurotic edges, to be further used to gradually extend all the layers of the anterior abdominal wall and skin within the postoperative period; in 7-8 days after the first operation, when the volume of the abdominal cavity becomes sufficient for layer-by-layer plastic surgery of the anterior abdominal wall, the second operation is performed, during which the postoperative cicatrix is excised with bordering incision and traction loops are removed, skin flaps are dissected from both sides to the outer edge of the rectus abdominis muscles, starting from the lower corner of the wound, individual muscular-aponeurotic nodal sutures are applied until the defect is completely closed, the skin is sutured with nodular sutures without tension.
Patent EA-032936-B1 (EA)
Title: Method of providing an image through a multiple lens array
Inventor: VAN DEN BERG JAN
IPC: B42D25/00
Filed: 2014-12-10
Abstract: The invention relates to a method of providing an image on a carrier, comprising the steps of providing the carrier comprising an array of lenses having a predetermined focal length, a distance between adjacent lenses being P micron, providing a removable optically active layer over the lenses whereby the focal length of the combined lenses and layer is increased, providing an image of an object in an image processing unit, providing the image through the array of lenses and through the optically active layer, and removing the active layer from the lenses, defining an array of target areas on the carrier and providing the image onto each target area via a projection lens system, a distance between adjacent target areas being L micron, and wherein the image is composed of pixels, the pixels of a first image being imaged via a laser onto a predetermined target area.
Patent EA-031966-B1 (EA)
Inventor: CHRISTENSEN HANS JOERGEN
IPC: F24S10/50
Filed: 2015-08-14
Abstract: Предложена панель (1) солнечного коллектора, выполненная для сбора тепловой энергии посредством нагревания воздуха. Панель (1) солнечного коллектора содержит воздушный канал (2) для направления воздуха через панель (1) между воздушным впуском (3) и воздушным выпуском (4), и панель (1) содержит средство (5) обеспечения воздушного потока, выполненное с возможностью создания воздушного потока через воздушный канал (2) от воздушного впуска (3) к воздушному выпуску (4). Панель (1) дополнительно содержит средство (6) поглощения света, расположенное в воздушном канале (2) или на нем для нагревания проходящего воздуха и средство (7) осушения воздуха, расположенное между воздушным впуском (3) и средством (6) поглощения света, причем средство (7) осушения воздуха выполнено с возможностью снижения абсолютной влажности проходящего воздуха. Также предложен способ работы панели (1) солнечного коллектора.
Patent EA-033448-B1 (EA)
Title: Modified release composition of orlistat and acarbose for the treatment of obesity and related metabolic disorders
Inventor: ALDERBORN GOERAN
IPC: A61K31/702
Filed: 2015-12-17
Abstract: The present invention relates to a modified release dosage form for the delivery of the drug substances orlistat and acarbose, wherein the dosage form comprises individually distinct parts with different release patterns: a) a first part, G1, comprising from about 5 to about 70% w/w of the total dose of acarbose and one or more of a hydrophobic polymer, a lipid and a wax; b) a second part, G2, comprising from about 30 to about 95% w/w of the total dose of acarbose and from about 10 to about 90% w/w of the total dose of orlistat, an enteric polymer and a surfactant; and c) a third part, G3, comprising from about 10 to about 90% w/w of the total dose of orlistat and one or more of a surfactant and a water-soluble polymer; and the total concentration of acarbose and orlistat, respectively, in the composition is 100% w/w. The invention provides improved therapeutic effect and reduction of side-effects.
Patent EA-034509-B1 (EA)
Title: Bentazone-based herbicidal composition for protection of leguminous crops
Inventor: SLAVASHEVICH MARINA ALEXANDROVNA
IPC: A01P13/02
Filed: 2018-02-06
Abstract: The present invention relates to the field of agrochemical compositions based on bentazone. In particular, the invention relates to a herbicidal composition of hydrophobic pesticides that are stable during storage and have increased efficiency in the protection of leguminous crops compared to common compositions. The obtained technical result consists in that bentazone is in a finely dispersed state, which provides high biological activity, the composition has a high chemical stability during storage, stability of the working fluid during use. The solve the set technical problem it is necessary to use a herbicidal composition including, as an active compound, 3-(1-methylethyl)-1H-2,1,3-benzothiadiazine-4(3H)-one 2,2-dioxide (bentazone) and an auxiliary substance. Bentazone is used in the form of an acid dissolved in an adjuvant, for which carboxazylic acid is used at a mass ratio of 1:(0.2-10)%, respectively.
Patent EA-037004-B1 (EA)
Title: Method for gradual sealing of a gas
Inventor: HOEFEL TORBEN
IPC: F04D29/58
Filed: 2017-02-20
Abstract: The invention relates to a method for gradual sealing of a gas in a compressor arrangement (100, 200, 300, 400) having a plurality of compression stages (I-VI), sequentially connected to each other via a main line (1), in which compression stages the gas conducted through the main line (1) is compressed from a suction-side pressure level to a pressure-side pressure level and heated from a suction-side temperature level to a pressure-side temperature level via said compression, wherein a return volume of the gas conducted through the main line (1) is extracted at least temporarily from the main line (1) downstream of one of the compression stages (V), supplied to a decompression, and supplied back into the main line (1) upstream of the same compression stage (V). It is provided that the pressure-side pressure level of the compression stage (V), downstream of which the return volume is extracted from the main line (1), is a supercritical pressure level, the decompression of the return volume occurs to a subcritical pressure level, the return volume is supplied to the decompression to the pressure-side temperature level of the compression stage (V), downstream of which the return volume is extracted from the main line (1), and the return volume is cooled only after the decompression and before and/or after the return into the main line (1). The invention further relates to a compressor arrangement (100, 200, 300, 400).
Patent EA-039476-B1 (EA)
Title: Magnetic coupling assembly
Inventor: Fuglesang Alexander
Filed: 2018-04-11
Abstract: The invention relates to a magnetic coupling assembly (1), comprising a rotatable male coupling member (2) comprising magnets (3), a rotatable female coupling member (4) comprising magnets (5), a static separation member (6) arranged between the male and female coupling members, a first channel (7) in a gap between the male coupling member and the separation member, a second channel (8) in a gap between the female coupling member and the separation member, an axial internal channel (9) in the male coupling member, a magnetic coupling section (10) of the static separation member, wherein said magnetic coupling section is the section of the static separation member between the magnets of the male coupling member and the magnets of the female coupling member, wherein the female and male coupling members are rotatable coupled by the magnets through the magnetic coupling section of the static separation member. The magnetic coupling assembly is distinguished in that the first channel, the second channel and the axial internal channel contain fluid (11) forced to flow through said channels for cooling and rotodynamic stabilization, and the magnetic coupling section of the static separation member has a length to diameter ratio larger than 1.
Patent EA-038556-B1 (EA)
Title: High temperature pyrolysis with a molten salt based catalyst system
Inventor: SPANU LEONARDO
Filed: 2019-04-04
Abstract: A catalyst system, which is active in pyrolyzing methane at reaction temperatures above 700°C, comprising a molten salt selected from the group consisting of the halides of alkali metals; the halides of alkaline earth metals; the halides of zinc, copper, manganese, cadmium, tin and iron; and mixtures thereof, the molten salt having dispersed therein one or more catalytically active forms of iron, molybdenum, manganese, nickel, cobalt, zinc, titanium, and copper in the form of finely divided elemental metals, metal oxides, metal carbides or mixtures thereof.
Patent ES-2165795-B1 (ES)
Title: Pastillero para cadena de reloj, pulseras cinturones y similares.
Inventor: CUNILL AMOROS MIGUEL ANGEL
IPC: A44C5/00
Filed: 2000-01-27
Granted: 2003-05-16
Abstract: Pastillero para cadena de reloj, pulseras, cinturones y similares. Que comprende un cuerpo de caja (1) y una tapa (2); y se caracteriza porque el cuerpo de caja (1) es solidario de la base (3a-3c) que sobresale respecto al cuerpo de caja (1), y que se fija a la cadena (6) mediante al menos un elemento elástico (5, 12). Cuenta con medios de enganche (4) del elemento elástico (5). También cabe la posibilidad de que el elemento elástico esté constituido por una pestaña (12) que se presenta como prolongación de la base (3c) tras sendos acodamientos (11).
Patent ES-2188378-B1 (ES)
Title: Procedimiento para la colocacion y/o instalacion de una bañera sobre otra bañera.
Inventor: MASCARELL SOLER JESUS
IPC: A47K3/04
Filed: 2001-06-04
Granted: 2005-06-16
Abstract: Procedimiento para la colocación y/o instalación de una bañera sobre otra bañera que comprende: desempalmar el desagüe y rebosadero de la bañera original, presentar sobre la bañera original otra bañera rígida nueva, insertando la misma con ajuste, retirar la bañera nueva, cortar, en su totalidad o en parte, la bañera original dejando, al menos, el ala perimetral de la misma, aplicar una sustancia adhesiva sobre el ala y partes no cortadas de la bañera original; aplicar la misma sustancia adhesiva en la bañera nueva, al menos, en las zonas de contacto con la bañera original, insertar con ajuste la bañera nueva en la bañera original, empalmar el desagüe y el rebosadero de la bañera nueva a los conductos correspondientes de la bañera original, llenar la bañera nueva, efectuar un sellado perimetral de tapado de los espacios entre el borde del ala de la bañera nueva y los paramentos y/o bordes del ala de la bañera original adyacentes.
Patent ES-2184634-B1 (ES)
Title: Barrera flexible para un lanzador de serpentinas o confeti.
Inventor: WILKINSON ROBERT A
IPC: F42B12/56
Filed: 2001-08-24
Granted: 2004-09-01
Abstract: Barrera flexible para un lanzador de serpentinas o confeti. La invención reemplaza un círculo de cartón suelto en el interior de un lanzador de serpentinas o confeti, un artículo de fiesta ya conocido. La invención tiene la forma de un cuenco. Su base es flexible (5) y es introducido al interior de la carcasa del lanzador (2). El borde del cuenco (1) es rígido y tiene zonas para acoplarse al lanzador. El lanzador emplea un dispositivo pirotécnico (4) muy pequeño capaz de ser iniciado estirando un cordón desde el exterior. La iniciación de la pirotecnia deforma la base flexible del cuenco (6). Esta deformación repentina sólo expulsa los contenidos del cuenco, es decir las serpentinas (3). El desgaste y detritus del componente pirotécnico es completamente contenido por la base del cuenco y su fijación rígida, el lanzador no expulsa cartón suelto del interior, cumpliendo el objeto principal de la invención.
Patent ES-2212889-B1 (ES)
Title: Plancha a vapor.
Inventor: URIEN ETXANIZ KARMELO
IPC: D06F75/18
Filed: 2002-06-17
Granted: 2005-10-01
Abstract: Plancha de vapor. La plancha incorpora un vaporizador (10) independiente de la suela, que está constituido por un cuerpo intercambiable y se ubica en un cajeado (9) establecido al efecto en la suela (3) de la plancha (1), bajo el depósito (5) de ésta, manera que mediante una pequeña bomba (13) prevista en el cuerpo de la plancha (1), se inyecta agua desde el depósito (5) al vaporizador (10) calentándose en ésta a la temperatura apropiada para convertirse en vapor que, después de pasar por los canales de distribución de la suela (3) salen al exterior a través de los orificios (7) establecidos en la superficie de planchado. El vaporizador (10) y la suela (3) quedan, en su acoplamiento, aislados térmicamente. Dicho vaporizador (10) es un cuerpo de aluminio inyectado sobre una resistencia tubular (11), al igual que la suela de la plancha (3) con su resistencia (4), con la particularidad de que los medios de regulación de la temperatura tanto de la suela como del vaporizador son independientes.
Patent ES-2217956-B1 (ES)
Inventor: TERRICABRAS BELART EMMA
IPC: C07D495/04
Filed: 2003-01-23
Granted: 2006-04-01
Abstract: New 4-aminothieno[2,3-d]pyrimidine-6-carbonitrile derivatives having the chemical structure of general formula (I), and pharmaceutically acceptable salts thereof are disclosed, as well as processes for their preparation and to pharmaceutical compositions containing them and their use in the treatment, prevention or suppression of pathological conditions, diseases and disorders susceptible of being improved by inhibition of PDE7.
Patent ES-2306541-B1 (ES)
Title: Trasplante funcional de la maquinaria de sumoilacion a escherichia coli.
Inventor: MENCIA CABALLERO MARIO
IPC: C07K1/00
Filed: 2004-04-16
Granted: 2009-09-28
Abstract: Trasplante funcional de la maquinaria de
sumoilación a  Escherichia coli . 
     La presente invención proporciona un método de
sumoilación  in vivo  de proteínas susceptibles de sumoilación 
mediante la transformación de células hospedantes con los
componentes de la maquinaria de sumoilación eucariota E1,  E2, de
SUMO y con dicha proteína, quimérica o no, susceptible de
sumoilación. Este método permite obtener proteínas  sumoiladas que
se encuentran implicadas en múltiples mecanismos de acción biológica
por lo que son de gran utilidad  en procesos de la industria
biotecnológica-farmacéutica, y además permite su
aplicación para la expresión, obtención y  purificación de proteínas
de interés comercial, dentro de una proteína quimérica susceptible
de sumoilación, al ser un  nuevo método de expresión génica.
Patent ES-2288346-B1 (ES)
Title: Aparato de tipo ciclon de recogida de polvo.
Inventor: OH JANG-KEUN
IPC: F15D1/00
Filed: 2005-02-14
Granted: 2008-11-16
Abstract: Aparato de tipo ciclón de recogida de polvo que presenta un cuerpo de ciclón provisto de una entrada de aire para succionar aire cargado de contaminantes y una salida de aire conectada con una fuente de aspiración al vacío. El vacío proporcionado por la fuente de vacío succiona aire desde la salida de aire, que discurre a través del cuerpo de ciclón desde la entrada de aire. Cuando el aire circula por el cuerpo de ciclón, forma una corriente turbulenta en éste. La corriente turbulenta crea una fuerza centrífuga sobre las partículas en suspensión en el aire que, por su mayor masa, hace que se separen del aire succionado desde la corriente turbulenta y hacia la salida de aire por la fuente de vacío. La salida de aire presenta un elemento de guía de paso, que disminuye la velocidad del aire descargado por ella y guía un flujo de forma aerodinámica.
Patent ES-2293790-B1 (ES)
Title: Sistema de calefaccion por circuito hidraulico.
Inventor: BLANCO FERNANDEZ PEDRO
IPC: F24D19/10
Filed: 2005-09-05
Granted: 2009-03-16
Abstract: El sistema consiste en establecer, entre un colector de ida (1) y un colector de retorno (2), convenientemente conectados a la caldera de calefacción, una pluralidad de líneas hidráulicas independientes (3), de alimentación de respectivas zonas o habitáculos (5) asistidos por respectivos termostatos, de manera que el radiador o radiadores de cada zona (5) actúan de forma independiente a los de las demás, en función de sus propias necesidades, determinadas por el termostato correspondiente a dicha zona y en su caso un programador de tiempo que controla los ciclos operativos en dicha zona. Se consigue de esta manera adecuar la temperatura de cada zona (5) a las necesidades específicas de la misma, con independencia de los demás, y consecuentemente un drástico ahorro energético.