baber/WOPTO huggingface dataset:
Patent CA-2879139-C (CA)
Inventor: CHU KATHERINE A
IPC: A61K47/24
Filed: 2013-07-17
Granted: 2021-05-11
Abstract: Liposomal compositions comprising peptide epoxyketone compounds are described, as well as methods of making and using such liposomal compositions. These liposomal compositions enhance the therapeutic window of peptide epoxyketone compounds by improving in vivo half-life relative to non-liposomal compositions comprising peptide epoxyketone compounds, providing desirable pharmacodynamic profiles, and providing anti¬ tumor activity in a human tumor xenograft model, greater than or equal to non-liposomal compositions comprising peptide epoxyketone compounds. Further, experiments performed in support of the present invention demonstrated improved tolerability of liposomal compositions comprising peptide epoxyketone compounds.
Patent CA-2879819-C (CA)
Inventor: IGNATCHENKO SERGEY
IPC: G06F12/14
Filed: 2013-06-18
Granted: 2021-04-20
Abstract: The systems, methods and apparatuses described herein provide a computing environment that includes secure time management. An apparatus according to the present disclosure may comprise a non-volatile storage to store a synchronization time and a processor. The processor may be configured to generate a request for a current time, transmit the request to a trusted timekeeper, receive a digitally signed response containing a current, real-world time from the trusted timekeeper, verify the digital signature of the response, verify that the response is received within a predefined time, compare a nonce in the request to a nonce in the response, determine that the current, real-world time received from the trusted timekeeper is within a range of a current time calculated at the apparatus and update the synchronization time with the current, real-world time in the response.
Patent CA-2881823-C (CA)
Inventor: FINKELSTEIN HOD
IPC: G01N21/64
Filed: 2013-03-08
Granted: 2019-06-11
Abstract: An integrated detection, flow cell and photonics (DFP) device (130) is provided that comprises a substrate (142) having an array of pixel elements (170) that sense photons during active periods. The substrate and pixel elements form an IC photon detection layer (155). At least one wave guide (118) is formed on the IC photo detection layer as a photonics layer. An optical isolation layer is formed over at least a portion of the wave guide. A collection of photo resist (PR) walls (132) patterned to define at least one flow cell channel (122) that is configured to direct fluid along a fluid flow path. The wave guides align to extend along the fluid flow path. The flow cell channel is configured to receive samples at sample sites that align with the array of pixel elements.
Patent CA-2892279-C (CA)
Title: Bone conduction apparatus and multi-sensory brain integration method
Inventor: REDFIELD RANDALL
IPC: H04R5/02
Filed: 2013-01-29
Granted: 2021-02-16
Abstract: The present disclosure provides a therapeutic method applicable to learning, attention, cognitive and developmental disorders. This method combines auditory, visual and vestibular stimuli into a systematic method which can be customized to address individual learning, attention and processing disorders. This method may be wirelessly implemented in a group setting. A device for providing vestibular and somatosensory stimulation through bone conduction of sound waves to skeletal bones is provided in the form of a pad that is applied to or wrapped around the individual in treatment, which is comfortable in use and may contain particulate filler material capable of providing bone conduction stimulation adjacent to the location of a bone conduction transducer and expand the sound conduction site over a larger area.
Patent CA-2896102-C (CA)
Title: Fluid bed coking process with decoupled coking zone and stripping zone
Inventor: DU BING
IPC: B01J8/18
Filed: 2014-02-21
Granted: 2019-09-17
Abstract: A fluid coking unit for converting a heavy oil feed to lower boiling products by thermal has a centrally-apertured annular baffle at the top of the stripping zone below the coking zone to inhibit recirculation of solid particles from the stripping zone to the coking zone. By inhibiting recirculation of the particles from the stripping zone to the coking zone, the temperatures of the two zones are effectively decoupled, enabling the coking zone to be run at a lower temperature than the stripping zone to increase the yield of liquid products.
Patent CA-2897031-C (CA)
Inventor: BAUDASSE YANNICK
IPC: B65H23/08
Filed: 2015-07-10
Granted: 2022-06-21
Abstract: A retractable tape spring in-building method for a deployable structure is provided. A main tape spring has an axis of deployment and of refurling substantially parallel to an unfurled axis X. A secondary tape spring has a winding mandrel carried by a shaft parallel to an axis Z perpendicular to the axis X. The main tape spring is wound around the mandrel. A first end of the main tape spring is fixed to the mandrel. A first end of the secondary tape spring is fixed spaced from a second end of the main tape spring. A second end of the secondary tape spring is fixed on the mandrel at a point distinct from the first end of the main tape spring. A deployable structure having a tape spring for a flexible structure is also provided. This is useful in space equipment, for example in optimizing volume.
Patent CA-2897221-C (CA)
Title: Controle de transporteur personnel fonde sur une position d'utilisateur
Inventor: KAMEN DEAN
IPC: A63C17/01
Filed: 2005-09-13
Granted: 2017-01-24
Abstract: Un contrôleur pour fournir une entrée dutilisateur dune direction voulue de déplacement ou dorientation pour un transporteur. Ce contrôleur présente une entrée pour recevoir une spécification dun utilisateur dune valeur en fonction dune orientation du corps détectée de lutilisateur. Lentrée spécifiée de lutilisateur peut être transmise par lutilisateur au moyen dune grande variété quelconque de modalités dentrée, notamment une détection de position corporelle ultrasonore, une détection de force de pied, une inclinaison de guidon, un guidon actif, une détection mécanique de position corporelle et une entrée directionnelle coulissante linéaire. Un appareil pouvant comprendre un guidon actif est prévu pour inviter un utilisateur à se positionner sur un véhicule de sorte à réduire une instabilité latérale causée par une accélération latérale du véhicule.
Patent CA-2911912-C (CA)
Title: Vehicle
Inventor: NADA MITSUHIRO
IPC: B60L7/20
Filed: 2015-11-13
Granted: 2017-12-19
Abstract: A vehicle includes: a fuel cell (100) that receives supply of fuel gas and generates electric power; a motor (150) that is driven by the generated electric power of the fuel cell (100); an electric power consuming auxiliary machine (135); a mechanical brake (190); a secondary cell (130), and a deceleration control unit (200). The deceleration control unit (200) limits the regenerative braking force to be obtained by the regenerative control, to an upper limit regenerative braking force corresponding to the maximum consumed electric power that the electric power consuming auxiliary machine (135) is capable of consuming such that regenerative electric power associated with regenerative braking is consumed by the electric power consuming auxiliary machine (135), and such that when the electric power consuming auxiliary machine (135) is incapable of consuming the regenerative electric power to the maximum consumed electric power, the residual regenerative electric power is consumed by charge of the secondary cell (130).
Patent CA-2916191-C (CA)
Title: A beverage apparatus and method
Inventor: WATSON BRIAN WAYNE
IPC: C12C13/00
Filed: 2014-06-30
Granted: 2021-11-23
Abstract: A beverage apparatus, system and methods for use are provided. The apparatus includes a pressure vessel configured to receive a flexible bag for containing a beverage. A pressure release valve is connected to the bag, and a pressure source connected to the pressure vessel. A temperature adjustment device is also provided to adjust temperature within the pressure vessel. A controller controls the temperature adjustment device and the pressure source to achieve a desired temperature and pressure within the pressure vessel according to a current mode of the apparatus, where the current mode is selected from a plurality of modes.
Patent CA-2919291-C (CA)
Inventor: ERICKSON DANIEL RAY
IPC: B62D55/08
Filed: 2016-01-28
Granted: 2018-05-01
Abstract: An off-highway vehicle has a front chassis portion, a rear chassis portion, a front ground drive system and a rear ground drive system. The front chassis portion has a front axle assembly having a front axle housing and a front axle shaft carrying a front wheel hub. The rear chassis portion has a rear axle assembly including a rear axle housing and a rear axle shaft carrying a rear wheel hub. The front ground drive system includes a front drive wheel mounted to the front wheel hub, a front idler wheel mounted to the front axle housing via a front drive frame member in front of the front drive wheel. The rear ground drive system has a rear drive wheel mounted to the rear wheel hub, a rear idler wheel mounted to the rear axle housing via a rear frame member behind the rear drive wheel.
Patent CA-2920797-C (CA)
Title: Form 2 crystalline polymorph of a salt of n-[1-6-(ethynyl-3-oxo-hexahydro-furo[3,2-b]pyrrole-4-carbonyl)-3-methyl-butyl]-4-[5-fluoro-2-(4-methyl-piperazinyl)thiazol-4-yl]-benzamide useful as cysteine protease inhibitor
Inventor: GRABOWSKA URSZULA
IPC: C07D491/048
Filed: 2014-08-13
Granted: 2021-06-15
Abstract: Abstract The cathepsin K inhibitor of the formula:   hl                             14' N  ¨N        0 S F has improved pharmaceutical properties as regards to crystallinity, moisture and thermal stability and solubility, and thereby utility in the oral treatment of osteoporosis, osteoarthritis and rheumatoid arthritis, when prepared as the Form 2 crystalline polymorph defined by N-[1-6-(ethynyl-3-oxo-hexahydro-furo[3,2-b]pyrrole-4-carbonyl)-3-methyl-butyl]-4-[5-fluoro-2-(4-methyl-piperazin-1-yl)thiazol-4-yl]-benzamide monohydrochloride and N41-6-(ethynyl-3-oxo-hexahydro-furo[3,2-b]pyrrole-4-carbonyl)-3-methyl-butyl]-445-fluoro-2-(4-methyl-piperazin-1-yl)thiazol-4-yl]-benzamide hydrate monohydrochloride with XRPD peaks including at least three peaks selected from 6.8, 14.9, 17.8, 24.1, 24.6 and 24.8 (  0.2 degrees, 2-theta values). The Form 2 crystalline polymorph can be prepared from the free base by reaction with HCI in the presence of a solvent selected from acetone, IPA, IPAc, Et0Ac, THF or MEK, and crystallisation by seeding or antisolvent addition. Date Recue/Date Received 2020-08-10
Patent CA-2923036-C (CA)
Title: Procede de regulation de la reactivite d'un reacteur a lit de boulets a haute temperature et refroidi au gaz, et barre de commande telescopique
Inventor: ZHANG ZUOYI
IPC: G21C7/10
Filed: 2014-09-03
Granted: 2018-06-05
Abstract: La présente invention concerne une barre de commande télescopique capable d'effectuer séparément un arrêt à froid et qui est agencée sur une couche réfléchissante latérale d'un réacteur. La barre de commande comprend une barre interne (1), une barre externe (2) et un ensemble cylindre de guidage (3) qui sont agencés verticalement et coaxialement, la barre externe (2) et l'ensemble cylindre de guidage (3) étant des objets cylindriques creux, l'extrémité supérieure de la barre interne (1) peut monter et descendre à l'intérieur de la barre externe (2), et son autre extrémité peut monter et descendre à l'intérieur d'un passage de barre de commande (6) qui est positionné en dessous de l'ensemble cylindre de guidage (3) et qui est agencé coaxialement avec l'ensemble cylindre de guidage (3) ; et l'extrémité supérieure de la barre externe (2) peut monter et descendre à l'intérieur de l'ensemble cylindre de guidage (3), et son autre extrémité peut monter et descendre à l'intérieur du passage de barre de commande (6). En partant du principe que la hauteur d'un récipient sous pression et les paramètres globaux de conception d'autres réacteurs modulaires à lit de boulets à haute température et refroidi au gaz existants sont inchangés, cette barre de commande peut en même temps augmenter la longueur effective d'une barre de commande jusqu'à un maximum, améliorer la valeur de réactivité d'un système à barres de commande et simplifier les opérations de commande de démarrage et de fonctionnement d'un réacteur modulaire à lit de boulets à haute température et refroidi au gaz, en créant ainsi une base technique permettant d'exploiter de manière sure et économique un centrale à réacteur à haute température.
Patent CA-2923755-C (CA)
Title: Filtrage automatique de variantes d'enzymes
Inventor: ZHANG XIYUN
IPC: C12Q1/00
Filed: 2014-09-26
Granted: 2023-03-14
Abstract: La présente invention concerne des procédés permettant d'identifier des biomolécules possédant des propriétés souhaitées (ou qui sont les plus appropriées pour une partie d'une évolution dirigée) à partir de bibliothèques de biomolécules complexes ou d'ensembles de ces bibliothèques. Certains modes de réalisation de la présente invention concernent des procédés permettant de filtrer virtuellement des protéines pour rechercher leurs propriétés bénéfiques. Certains modes de réalisation de la présente invention concernent des procédés permettant de filtrer virtuellement des enzymes pour rechercher une activité souhaitée et/ou une sélectivité souhaitée pour des réactions catalytiques impliquant des substrats particuliers. Certains modes de réalisation combinent le filtrage et l'évolution dirigée pour concevoir et développer des protéines et des enzymes possédant des propriétés souhaitées. L'invention concerne également des systèmes et des produits de programmes informatiques qui mettent en uvre les procédés.
Patent CA-2931796-C (CA)
Title: Robinet-vanne pour poussiere et materiaux abrasifs dote d'un siege de robinet incline
Inventor: SURPRENANT DEAN
IPC: F16K3/02
Filed: 2016-05-31
Granted: 2023-10-17
Abstract: Un robinet-vanne à poussière et à matériaux abrasifs comprenant un siège de corps en angle et un clapet installé en relation de pivot permet une grande zone détanchéité autour de la périphérie du siège de corps, qui peut être fermé de manière étanche par une action coinçage en raison de la force accrue appliquée par lactionneur de robinet. Le joint de robinet nest donc pas formé le long dune surface linéaire unique comme dans les robinets-vannes traditionnels et la force appliquée par le clapet sur le siège facilite la formation, même en cas dusure le long des surfaces détanchéité. En raison de la zone ouverte relativement grande autour de la périphérie du clapet juste avant la fermeture ou immédiatement à louverture, la vitesse des particules dans les systèmes sous pression est réduite et lérosion est réduite conséquemment.
Patent CA-2933307-C (CA)
Inventor: BUZZETTI ALEX
IPC: B60W50/14
Filed: 2014-12-09
Granted: 2021-10-19
Abstract: The present invention relates to a system (1) for estimating the driving style of a vehicle, comprising: - a device for measuring the longitudinal acceleration (ax) and lateral acceleration (ay) of a vehicle along a measuring path; - a memory module (7) in which pairs of the admissible limit values of the longitudinal and lateral accelerations are stored. Such values implement an admissible acceleration curve, closed in a longitudinal acceleration-lateral acceleration plane; - an elaboration module (6) configured for: - associating to each measured longitudinal acceleration - lateral acceleration pair of the vehicle a corresponding longitudinal acceleration - lateral acceleration pair on said admissible acceleration curve; - providing an indication of the driving style on the basis of the trend of position of the measured longitudinal acceleration - lateral acceleration pair with respect to the corresponding longitudinal acceleration - lateral acceleration pair on the admissible acceleration curve along the measuring path. The present invention also relates to a method for estimating the driving style of a vehicle.
Patent CA-2939044-C (CA)
Inventor: KLAMCZYNSKI KATHARINE
IPC: A01N47/24
Filed: 2015-02-19
Granted: 2022-09-20
Abstract: La présente invention concerne un procédé qui permet d'obtenir une co-formulation aqueuse de métalaxyl avec au moins un autre composé pesticide modérément organique PC ayant une solubilité dans l'eau d'au plus 1 g/l à 20 °C et un point de fusion compris dans la plage allant de 40 à 0 °C, ledit procédé comprenant les étapes suivantes : l'utilisation d'une composition aqueuse de métalaxyl, le métalaxyl étant essentiellement présent sous forme dissoute dans une phase aqueuse contenant de l'eau et au moins un tensioactif ; le mélange d'une suspension aqueuse du composé pesticide organique PC avec la composition aqueuse de métalaxyl.
Patent CA-2942043-C (CA)
Inventor: CHEN XIAO-GUANG
IPC: C22C21/00
Filed: 2015-03-31
Granted: 2017-04-25
Abstract: An aluminum alloy composition includes, in weight percent: less than or equal to 0.70 iron; less than or equal to 0.30 silicon; and less than or equal to 0.30 copper, with the balance being aluminum and other elements, with the other elements being present at up to 0.05 weight percent each and up to 0.15 weight percent total.  The alloy is homogenized at a temperature of 520°C to 570°C for 2-10 hours. The volume phase fraction of a-AlFeSi phase present in the homogenized aluminum alloy product may be at least 10%.
Patent CA-2943414-C (CA)
Inventor: FORD COLIN P
IPC: B65B43/26
Filed: 2015-06-26
Granted: 2019-06-18
Abstract: A packaging machine for placing articles into a carton includes rotating flight assemblies that receive a carton or carton blank, and rotate the carton blank and carton with articles while the flight assemblies move downstream. The flight assemblies each include two fixed segments and one segment that includes a block and associated bracket that rotate as the flight assembly is pulled through the machine by a conveying system. A method includes carton blanks being fed by a carton feeder onto the flight assemblies. Articles are formed into an article group, which is then placed onto a carton blank. As the blank and article group move in a downstream direction, the side panels of the carton blank are wrapped around the article group and the carton and article group are rotated to assist in closing the carton end flaps.
Patent CA-2945926-C (CA)
Inventor: SAKAI ATSUSHI
IPC: G01C21/00
Filed: 2016-02-29
Granted: 2018-09-25
Abstract: A control system for a work machine is provided with a position detecting device, a non-contact sensor, a map data generating unit, a first storage unit, a second storage unit, an integrated map data calculation unit, and a position calculation unit. The position detecting device detects the position of a work machine. The non-contact sensor detects an object in a non-contact manner. The map data generating unit generates map data based on detection data from the position detecting device and detection data from the non-contact sensor. The first storage unit stores past map data generated in the map data generating unit based on the detection data from the position detecting device and the detection data from the non-contact sensor acquired in a predetermined period in the past. The second storage unit stores current map data generated in the map data generating unit based on the detection data from the position detecting device and the detection data from the non-contact sensor. The integrated map data calculation unit calculates integrated map data by integrating the past map data stored in the first storage unit and the current map data stored in the second storage unit. The position calculation unit by matching the integrated map data calculated by the integrated map data calculation unit and the detection data from the non-contact sensor, calculates the position of the work machine.
Patent CA-2957364-C (CA)
Title: Sequencing batch facility and method for reducing the nitrogen content in waste water
Inventor: GINESTET PHILIPPE
IPC: C02F3/12
Filed: 2015-07-30
Granted: 2024-01-02
Abstract: A method for treating effluents containing nitrogen in the form of ammonium, implementing chemical reactions for oxidising and reducing the nitrogen in a sequencing batch reactor, the method comprising: -a feeding step, which involves introducing a volume of effluents to be treated into the reactor, -at least one first aeration step, which involves injecting oxygen or air into the reactor for partial oxidation of the ammonium into nitrites and/or nitrates, -a second anoxic step, which involves interrupting the injection of oxygen or air, thus producing gaseous nitrogen, -a settling step, during which the sludge is deposited at the bottom of the reactor and the content of the reactor is clarified close to the surface of same, -a draining step, which involves discharging a clarified fraction of the content of the reactor, said draining and feeding steps taking place simultaneously, in which, during the feeding step, the volume of effluents to be treated is introduced close to the bottom of the reactor, and in which, during the draining step, the clarified fraction of the content of the reactor is discharged at a predefined discharge level close to the surface of the content of the reactor.
Patent CA-2958349-C (CA)
Inventor: KERESTES JASON
IPC: B66F3/00
Filed: 2017-02-15
Granted: 2021-02-09
Abstract: A lifting support device that includes a linear actuator including a first end configured to support an object, and a load sensor positioned to determine application of a first load on the load sensor by at least the object. The linear actuator is maintained in equilibrium when supporting the first load. The lifting support device further includes a controller coupled in communication with the load sensor, and the controller is configured to selectively actuate the linear actuator in response to application of a second load on the load sensor.
Patent CA-2959441-C (CA)
Inventor: LAWLER JUSTIN
IPC: B67D1/07
Filed: 2014-08-27
Granted: 2022-07-19
Abstract: A cleaning system for a beverage dispenser, comprising a drainage conduit for connecting an outlet of the beverage to a drain, the drainage conduit comprising: an inlet at one end thereof connected to the outlet of the beverage dispensing system, an outlet at an opposite end of the conduit, a valve between the inlet and outlet, opening at a preset pressure. A method of cleaning a beverage dispensing system comprising a plurality of beverage dispensing conduits, using a cleaning system with pressure-actuated valves. A beverage dispensing tap comprising an inlet, an outlet and a valve between the inlet and outlet, opening at preset pressure. A beverage conduit cleaning system comprising a portable alarm device including a timer and an alarm, the alarm being activated after a predetermined time in response to the removal of the portable alarm, the alarm being removable from the beverage cleaning system.
Patent CA-2960086-C (CA)
Title: Digital radio broadcast receiver, broadcasting methods and methods for tagging content of interest
Inventor: DILLON ROBERT MICHAEL
IPC: H04H20/93
Filed: 2008-09-03
Granted: 2020-04-14
Abstract: A method for specifying content of interest using a digital radio broadcast receiver is described. A digital radio broadcast signal includes first audio content and first program data, wherein the first program data includes information identifying a first item, and includes second audio content and second program data, wherein the second program data includes information identifying a second item. A user command entered at a user interface during reception of audio content is registered, indicating a user's interest in either the first or second audio content. It is determined whether there is an ambiguity in the content of interest. If an ambiguity exists, a first data structure is stored for the first audio content, and a second data structure is stored for the second audio content. The first data structure includes the information identifying the first item, and the second data structure includes the information identifying the second item.