baber/WOPTO huggingface dataset:
Patent EP-0623127-B1 (EP)
Inventor: WILKERSON WENDELL WILKIE
IPC: A61K31/4418
Filed: 1992-12-30
Granted: 1997-04-02
Abstract: On a découvert que des composés de formule (I) stimulent la libération du neurotransmetteur acétylcholine et peuvent par conséquent être utiles dans le traitement de maladies humaines telles que la maladie d'Alzheimer et d'autres pathologies liées à l'apprentissage et à la cognition, dans lesquelles on a détecté des niveaux inférieurs à la normale de cette substance neurochimique. Les composés de cette invention sont décrits dans la formule (I) dans laquelle Q représente (a) ou (b), A et B sont indépendamment sélectionnés dans le groupe formé par H, R4, -OH et -OCOR4, ou A et B forment ensemble =O, =S, =CH¿2?, =CHR?4, =C(R4¿), =NOH, =NOR4, 1,3-dioxane, 1,3-dioxolane, 1,3-dithiane ou 1,3-dithiolane; R1 représente 4-, 3-, ou 2-pyridyle, pyrimidyle, pyrazinyle, 2-fluoro-4-pyridyle ou 3-fluoro-4-pyridyle; R2 représente alkyle comprenant de 1 à 10 atomes de carbone, cycloalkyle comprenant de 3 à 8 atomes de carbone, 2-, 3-, ou 4-pyridyle, Phe ou Phe-W, Phe représente un groupe phényle; W représente F, Cl, Br, R4, -OH, -OR4, -NO2, -NH2, -NHR?4, -NR4R4¿, -CN, -S(O)¿m?-R?4; R3¿ représente H, F, Cl, Br, -CN, -OH, -NO¿2?, -NH2, -CF3, -NHR?4, -NR4R4, R4, -OR4¿, -S(O)¿m?-R?4, R4 et R4'¿ représentent alkyle comprenant de 1 à 4 atomes de carbone, CH¿2?Phe-W ou Phe-W; R?5¿ représente -(CH¿2?)m-Y ou -OCOR?4¿; Y représente H, OH, NH¿2?, -NHR?4, -NR4R4¿, -NHCOR4, -NHCO¿2R?4, F, Cl, Br, OR4, -S(O)¿m?R?4, -CO¿2H, -CO2R4, -CN, -CONR4R4, -CONHR4, -CONH¿2?, -COR?4¿; -CH=CHCO¿2?R?4, -OCOR4¿, Phe, Phe-W, -C=CCO¿2R?4, -CH=CHR4, ou -C=CR4; m vaut 0, 1 ou 2; n est compris entre 1 et 7; à condition que lorsque Q représente indoxyle et R5 représente (CH¿2?)nY, Y ne représente pas OH. Les sels physiologiquement appropriés de ces composés sont également décrits dans cette invention.
Patent EP-0626969-B1 (EP)
Inventor: WINKLER JAMES DAVID
IPC: A61K31/421
Filed: 1993-02-11
Granted: 2000-05-24
Abstract: Coenzyme A-independent transacylase is required for the release of free arachidonic acid, and the production of arachidonic acid metabolites and platelet activation factor. Blocking of this enzyme inhibits the production of these inflammatory mediators and will be of therapeutic utility in a broad range of allergic and inflammatory diseases and disorders. Compounds are described herein which inhibit the action of CoA-IT and are therefore useful in the treatment of disease states caused thereby.
Patent EP-0640203-B1 (EP)
Inventor: KREBS GEORG
IPC: F26B25/00
Filed: 1993-05-19
Granted: 1996-04-03
Abstract: A sludge drying system using exhaust air from a furnace in a direct heat, rotary drum dryer to simultaneously dry and pelletize the sludge. The dried sludge particles exiting the dryer is entrained in the exhaust air. The sludge particles are separated from the exhaust air and then classified according to size. The exhaust air is treated in a treatment section, and then divided into two exhaust air streams or portions. A first portion of the exhaust air is discharged into the environment, while the second, larger portion of the exhaust air is recycled back to the furnace to be used to dry the sludge in the drier. In one embodiment, the exhaust air treatment section is provided with a spray condenser and a bio-filter. In another embodiment, the exhaust air treatment section is provided with a heat exchanger for exhaust air. In yet another embodiment, the exhaust air treatment section is provided with a heat exchanger for the cooling water of the condenser as well as a heat exchanger for the recycled exhaust air. In still another embodiment, the exhaust air treatment section is provided with a plurality of heat exchangers and the furnace is modified with an exhaust air deodorizing chamber.
Patent EP-0606432-B1 (EP)
Inventor: BATTERHAM ROBIN JOHN
IPC: B01F3/04
Filed: 1993-07-09
Granted: 1997-03-12
Abstract: PCT No. PCT/AU93/00340 Sec. 371 Date Mar. 16, 1994 Sec. 102(e) Date Mar. 16, 1994 PCT Filed Jul. 9, 1993 PCT Pub. No. WO94/01210 PCT Pub. Date Jan. 20, 1994.A reactor for introducing gas into a fluid comprises a mixing tank (12, 43) for the fluid and a partition means (13,45) for dividing the tank into at least two chambers (21, 89) and (23, 91). The reactor further comprises a first pump means (14, 47) located in one of the chambers for circulating the fluid downwards in one chamber and then upward in the other chamber and an aerator assembly (29, 49) for aerating a sidestream of the fluid and introducing the aerated fluid into the tank for mixing the aerated fluid with the circulating fluid in the tank. The aerator assembly comprises a bank of venturi aerators (38, 57) each having an aerator inlet; an aerator outlet; and a constriction intermediate the aerator inlet and the aerator outlet for creating a region of reduced pressure in the fluid, the constriction being elongate in a section transverse to the direction of flow of the fluid through the constriction; and a means for introducing the gas into the constriction to aerate the fluid.
Patent EP-0613491-B1 (EP)
Inventor: BUCHWEITZ JOERG
IPC: C09D11/10
Filed: 1993-09-09
Granted: 1997-01-08
Abstract: The invention concerns a water-based ink suitable for the printing of products which can be de-inked using a flotation process, the ink containing essentially (a) 1-50 % by wt. of one or more inorganic or organic pigments; (b) 1-50 % by wt. (solids) of one or more water-dilutable non-ionic and/or self-crosslinking resins; (c) 0-25 % by wt. of one or move low-boiling alcohols; (d) 10-90 % by wt. of water and (e) 0-20 % by wt. of auxiliaries.
Patent EP-0625905-B1 (EP)
Inventor: SUFFIS ROBERT
IPC: A61Q15/00
Filed: 1993-09-22
Granted: 2004-12-01
Abstract: Described is a fragrancing composition having fragrancing components that are not activated until, e.g., application to the skin of a human. The composition is alkaline or (if anhydrous) capable of producing an alkaline pH when in contact with water, prior to application, and includes (1) a vehicle such that when the composition is in contact with water, prior to application, the composition is at an alkaline pH; and (2) at least one potential fragrance that is at least one compound having little or no odor in the alkaline composition but which, e.g., is hydrolyzed in a lower pH environment to produce compounds having a relatively strong aroma. Upon application of the alkaline composition to the skin surface, the strong buffering capacity of the skin (the surface of which has a normal pH of 5.5-7.0) neutralizes alkalinity of the composition (lowers pH) so as to restore normal skin surface pH; the potential fragrance is then hydrolyzed at the lower pH to release the compound having relatively strong aroma. The potential fragrance can be incorporated as a component of a transparent (clear) deodorant stick composition for application to human axillary regions, the fragrance being released after application to the body.
Patent EP-0642072-B1 (EP)
Inventor: KIEHL OLIVER DR ING
IPC: G05F3/26
Filed: 1994-09-02
Granted: 1997-05-07
Abstract: A current mirror includes first through eighteenth transistors. The load paths of the first and second transistors are in series for carrying an input current to a first supply potential. The control terminals of the first through eighth transistors receive the input current. The load paths of the fourth, third, ninth and tenth transistors are in series between the first and a second supply potential. The third and ninth transistors form a tap being connected to the control terminals of the ninth, tenth, eleventh, twelfth and thirteenth transistors. The load paths of the fifth, sixth, eleventh and fourteenth transistors are in series between the first and second supply potentials. The sixth and eleventh transistors form a tap being connected to the control terminals of the fourteenth through sixteenth transistors. The load paths of the seventeenth, seventh, twelfth and fifteenth transistors are in series between the first and second supply potentials. The seventh and twelfth transistors form a tap being connected to the control terminals of the seventeenth and eighteenth transistors. The load paths of the eighteenth and eighth transistors are in series for tapping a first output current proportional to the input current from the first supply potential. The load paths of the sixteenth and thirteenth transistors are in series for tapping a second output current equal to the first from the second supply potential. The ninth through sixteenth transistors are of one, and the seventeenth, eighteenth and first through eighth transistors being of the other, conduction type.
Patent EP-0651225-B1 (EP)
Inventor: GOUBEAUD KARL-HEINZ
IPC: F41G1/34
Filed: 1994-09-22
Granted: 2000-01-12
Abstract: The invention relates to a sighting device (aiming device) which has one optical axis. In addition, the sighting device contains an illuminating device, which emits coloured light, in order to produce a coloured target marker, the target marker being imaged into the eye of the person using the sight. The invention comprises the illuminating device containing luminescent material which is illuminated by natural light (daylight, bright moonlight) or another light source. In this way, an illuminating device is obtained which can dispense with an artificial light source for producing a coloured target marker and without most of the intensity of the natural light being lost by a filter. <IMAGE>
Patent EP-0648733-B1 (EP)
Inventor: SCHWARZ FRANZ THOMAS DIPL-ING
IPC: C07C227/18
Filed: 1994-10-07
Granted: 1998-01-21
Abstract: Process for transesterification of dimethyl succinylsuccinate using one or more aliphatic alcohols, which in each case have at least 2 C atoms, in the presence of an acidic catalyst with or without the presence of a diluent which is inert under the reaction conditions, with exclusion of oxygen and under pressure, at least one of the two methoxy groups being replaced by the oxy group corresponding to the alcohol used, and use of the process in a process for preparation of terephthalic acid and of quinacridones.
Patent EP-0627008-B1 (EP)
Inventor: JUNINO ALEX
IPC: A61K8/00
Filed: 1993-11-19
Granted: 2000-05-31
Abstract: PCT No. PCT/FR93/01138 Sec. 371 Date Jul. 18, 1994 Sec. 102(e) Date Jul. 18, 1994 PCT Filed Nov. 19, 1993 PCT Pub. No. WO94/12653 PCT Pub. Date Jun. 9, 1994The present invention relates to a method for the preparation of a melanic pigment by enzymatic bioconversion, implementing a melanin precursor substrate and plant cells, characterized in that: (a) poppy (Papaver somniferum) plant cells previously cultivated are separated from their culture medium and subcultured in a culture medium with a concentration from 10 to 100 g/l; (b) the cells are ground at least partially, before or at the end of the latency time, (c) the at least partially ground cells are placed in a bioconversion medium in the presence with a melanin precursor substrate selected amoung indol, indolin, dihydroxyphenylalanin, tyramin and tyrosin; (d) the precipitated melanic pigment is collected. The invention also relates to the utilization of such resulting pigments for the preparation of cosmetic compositions.
Patent EP-0619702-B1 (EP)
Inventor: VAN DER LELY CORNELIS
IPC: A01K1/12
Filed: 1993-11-01
Granted: 2000-09-27
Abstract: A construction for automatically milking animals, such as cows, comprises a milking box (14) with a milking robot (41) and an area (1, 28) where the animals can freely move about. The construction further includes a system of doors, gates or suchlike means (8 -12) which open in one direction to define the path and the direction of walking of the animals to the milking box (14). The milking box (14) includes two adjacently arranged milking box compartments (15, 16). In this situation, the milking robot (41) is set-up in such a manner that the head (67) of the robot (41) can enter a first compartment from one side and a second compartment from another side.
Patent EP-0686127-B1 (EP)
Inventor: ZAHN ERICH MICHAEL
IPC: B65H31/30
Filed: 1994-01-27
Granted: 1997-04-09
Abstract: PCT No. PCT/EP94/00219 Sec. 371 Date Aug. 28, 1995 Sec. 102(e) Date Aug. 28, 1995 PCT Filed Jan. 27, 1994 PCT Pub. No. WO94/19270 PCT Pub. Date Sep. 1, 1994The invention relates to a device for the non-stop operation of a delivery unit of a rotary printing machine in which sheets in a flow of sheets are collated into individual stacks supported on a stack base with a surface interrupted by grooves and in which auxiliary stacks are borne by grid rods together forming a rack until their transfer to the stack base, the grid rods penetrating into the grooves during transfer. To prevent the stacks from being hampered by their weight, according to the invention a receiving plate catching the auxiliary stack from below is laid upon the grid rods in their reception position.
Patent EP-0655044-B1 (EP)
Inventor: GRAY ALAN
IPC: B65D85/73
Filed: 1993-08-24
Granted: 1999-04-14
Abstract: PCT No. PCT/GB93/01805 Sec. 371 Date Apr. 10, 1995 Sec. 102(e) Date Apr. 10, 1995 PCT Filed Aug. 24, 1993 PCT Pub. No. WO94/04433 PCT Pub. Date Mar. 3, 1994A fluid container and capsule therefor. The capsule comprises upper and lower parts, at least one of which has a dished formation and both of which have a peripheral rim, the rims being secured together so that the upper and lower parts are at least partially in register with one another to provide at least one vented chamber extending into the dished formation. The capsule includes a vent hole or like structure in at least one of the parts to communicate between the interior of the chamber and the exterior thereof. The lower part has its exterior so formed as to enable it to be held in stable engagement with a surface but so that a fluid may pass freely between those parts of the exterior of the lower part and the surface that are not in intimate engagement.
Patent EP-0691017-B1 (EP)
Inventor: BERGLOF FREDRIK
IPC: G09F7/04
Filed: 1994-03-25
Granted: 1998-07-01
Abstract: PCT No. PCT/SE94/00273 Sec. 371 Date Nov. 6, 1995 Sec. 102(e) Date Nov. 6, 1995 PCT Filed Mar. 25, 1994 PCT Pub. No. WO94/23409 PCT Pub. Date Oct. 13, 1994A magnetic fastening device comprises a magnetic attraction member (11, 12) including a permanent magnet (16, 17) and an elongate tubular sheath (13) which is made of nonmagnetic material and tightly encloses the magnetic attraction member (12, 13). Two magnetic attraction members may be interconnected by a flexible hinge member which is integral with the sheaths of the members and formed from a length (13) of shrink tubing.
Patent EP-0712278-B1 (EP)
Inventor: KIMURA TOKIYA
IPC: A01N43/40
Filed: 1994-08-10
Granted: 2001-06-13
Abstract: PCT No. PCT/JP94/01320 Sec. 371 Date Feb. 9, 1996 Sec. 102(e) Date Feb. 9, 1996 PCT Filed Aug. 10, 1994 PCT Pub. No. WO95/04460 PCT Pub. Date Feb. 16, 1995N-pyridyltoluidine-containing fungicidal water dispersible granule which comprises 3-chloro-N-(3-chloro-5-trifluoromethyl-2-pyridyl)- alpha , alpha , alpha -trifluoro-2,6-dinitro-p-toluidine as a fungicidal active component, a surfactant and a carrier, and of which a 1% water suspension is acescent.
Patent EP-0717598-B1 (EP)
Title: Coffee torrefaction process
Inventor: CLAUZURE ANDRE
IPC: A23F5/04
Filed: 1994-09-05
Granted: 1997-12-29
Abstract: PCT No. PCT/FR94/01037 Sec. 371 Date Mar. 7, 1996 Sec. 102(e) Date Mar. 7, 1996 PCT Filed Sep. 5, 1994 PCT Pub. No. WO95/07026 PCT Pub. Date Mar. 16, 1995A process for obtaining a ground roasted plant material is disclosed. The process includes the steps of subjecting the plant material to steam at a pressure greater than or equal to about 5 bar to roast the plant material, and releasing the pressure to expel the plant material through a grid to grind the roasted plant material.
Patent EP-0729494-B1 (EP)
Inventor: BENNETT GREGGORY S
IPC: C09J151/06
Filed: 1994-10-05
Granted: 1998-08-12
Abstract: A pressure sensitive thermosetting adhesive that is the polymerization product of a blend that includes: (a) a polymerizable monomeric or prepolymeric syrup comprising: (i) 10-80 parts by weight of an acrylic acid ester of a monohydric alcohol whose homopolymer has a Tg less than 0 °C; (ii) 20-90 parts by weight of a non-polar ethylenically unsaturated monomer whose homopolymer has a solubility parameter of no greater than 10.50 and a Tg greater than 15 °C; and (iii) 0-5 parts by weight of a polar ethylenically unsaturated monomer whose homopolymer has a solubility parameter of greater than 10.50 and a Tg greater than 15 °C; and (b) one or more thermosetting resins.
Patent EP-0678255-B1 (EP)
Inventor: RIOJA CALVO MIGUEL ANGEL D
IPC: A47B88/00
Filed: 1995-03-24
Granted: 1998-07-08
Abstract: The runner-rails (2,3) are joined to the drawer front (4). The drawer has a removable, single-piece shell (1) which has a collar (1a) on its long sides, extended by a protruding skirt (1b) containing assembly ducts. Each guide (2,3) has a front (6) and back (7) fixture fitting into the ducts with a seating for the top of the ducts. The back of the drawer front has a coupling (8). The front holders have a vertical cavity (10) opening forwards into the connecting plane with the drawer front. The two side surfaces of the cavity have guide rails matching guide grooves in the back couplings. <IMAGE>
Patent EP-0705599-B1 (EP)
Inventor: ASCIONE JEAN-MARC
IPC: A61Q11/00
Filed: 1995-08-23
Granted: 1996-09-25
Abstract: Use of carbamate esters of formula R1R2CHCH2OC(O)N(R3)A (I) as surfactants in cosmetic or pharmaceutical compsns. R1 = opt. unsatd. 4-6C alkyl; R2 = opt. unsatd. 2-4C alkyl; R3 = H or opt. unsatd. 1-6C alkyl; A = a hydrophillic non-ionic gp. The compsns. contain 0.1-10 (pref. 0.5-5) wt.% (I), opt. with another surfactant, which may be sodium lauryl sulphate or sodium laureth sulphate.
Patent EP-0731899-B1 (EP)
Inventor: WOOD JOHN
IPC: F24H9/00
Filed: 1994-11-25
Granted: 2000-03-29
Abstract: A condensing boiler (1) comprises a heat exchanger (5) having a cylindrical first heat exchange wall (6) surrounded by an outer water chamber (10). A plug (17) extends into the first heat exchange wall (6) and forms a combustion chamber (22) and an annular downwardly extending flue gas passageway (23) for accommodating flue gases from the combustion chamber (22). The plug (17) comprises an outer shell (18) which forms a second heat exchange wall (19) and an inner cylindrical shell (35) which forms with the outer shell (18) an inner water chamber (36). A connecting pipe (46) connects the inner water chamber (36) to the outer water chamber (10) so that water flows in series through the inner water chamber (36) and the outer water chamber (10) from a return water inlet (42) in the inner water chamber (36) to a flow water outlet (16) from the outer water chamber (10).
Patent EP-0738328-B1 (EP)
Inventor: BEHR JEAN-PAUL
IPC: A61K9/127
Filed: 1995-01-09
Granted: 2005-12-07
Abstract: The present invention relates to compositions comprising at least one nucleic acid and one lipopolyamine, and their utilisation in gene therapy, particularly for the transfert in vivo of nucleic acids.
Patent EP-0717722-B1 (EP)
Inventor: BORGSTEDT ERIC VON REHREN
IPC: C01B33/38
Filed: 1995-03-15
Granted: 2000-01-12
Abstract: A crystalline hydrated layered sodium and potassium silicate/amorphous sodium and potassium silicate composite material with predetermined hardness ion sequestration properties is achieved by controlling the process for forming the material. The process for producing the crystalline hydrated layered sodium and potassium silicate/amorphous is sodium and potassium silicate composite comprises hydrolyzing DB-1 crystalline sodium and potassium silicate glasses as a precursor material to produce the composite material known as DB-2. Hydrolysis of the DB-1 precursor material is achieved by adding typically up to 100.0 milliequivalents per gram of H3O+ ions or up to 50 milliequivalents per gram of OH- ions. The resulting DB-2 material can sequester CA2+ ions, Mg+ ions, or both, depending on the results desired, processing conditions, and starting materials used.
Patent EP-0761038-B1 (EP)
Title: Dispositif a oscillateur a frequence variable
Inventor: HOHMANN HENNING
IPC: H03B5/12
Filed: 1995-05-12
Granted: 1999-01-20
Abstract: Dispositif à oscillateur à fréquence variable, notamment pour syntoniseur, dans lequel le réseau de contre-réaction (100) pour l'amplificateur de l'oscillateur (1) comprend un circuit en série présentant deux inductances (6, 7) de circuit oscillant et un condensateur (8) de circuit oscillant, avec lequel le circuit en série d'un autre condensateur (15) de circuit oscillant à une capacité réglable (18, 20, 22) est monté en parallèle. Des moyens de commutation (9, 17, 21) sont connectés aux n÷uds de couplage (30) des deux inductances (6, 7), moyens grâce auxquels le premier condensateur (8) de circuit oscillant et l'inductance (7) de circuit oscillant connectés à ce condensateur peuvent être court-circuitées sous la commande d'un signal de commutation (S). Le réseau de contre-réaction (100) peut ainsi être commuté entre deux bandes de fréquence et est symétrique par rapport à l'effet haute fréquence.
Patent EP-0760687-B1 (EP)
Inventor: RIPAMONTI UGO
IPC: A61L27/00
Filed: 1995-05-24
Granted: 2002-08-28
Abstract: PCT No. PCT/NL95/00181 Sec. 371 Date Nov. 22, 1996 Sec. 102(e) Date Nov. 22, 1996 PCT Filed May 24, 1995 PCT Pub. No. WO95/32008 PCT Pub. Date Nov. 30, 1995This invention relates to a biomaterial useful in bone repair and replacement, and to implants for cranofacial, orthopaedic, and especially dental applications. The implants have a unique geometric configuration, their surfaces defining concavities having a shape and dimensions which induce or enhance the rate and/or amount of bone growth at the implant site. The biomaterial preferably has a specific porous configuration and the implant may be at least coated with such a biomaterial of hydroxyapatite, for example.
Patent EP-0802810-B1 (EP)
Inventor: MICHEL PETER
IPC: A61M5/315
Filed: 1995-11-09
Granted: 2001-10-10
Abstract: PCT No. PCT/CH95/00261 Sec. 371 Date Sep. 15, 1997 Sec. 102(e) Date Sep. 15, 1997 PCT Filed Nov. 9, 1995 PCT Pub. No. WO97/17095 PCT Pub. Date May 15, 1997The present invention provides an injection system including a disposable lower part and a reusable upper part wherein the lower part includes an ampoule holder for accommodating a container containing a liquid medicament and having an axially movable plug having a cross-section F for ejecting the liquid medicament from the container and a kinematic device for axially driving the plug forward by a number N of individual steps x, N being a natural number, and the reusable upper part includes a casing detachably connectable to the ampoule holder, and a dosing button for selecting the number N of individual steps x and for actuating the kinematic device of the lower part which thereby effects selectable ejection of a Volume V=NxF of the liquid medicament from the container.
Patent EP-0758620-B1 (EP)
Inventor: HAUCK ERICH
IPC: B65D90/507
Filed: 1996-08-10
Granted: 2003-04-09
Abstract: An inner lining for liquid tanks, esp. petrol tanks (1),comprises: (a) a petrol-resistant inner shell (6) with a diffusion- proof layer (6a), on the side facing the wall of the tank; and (b) an electrically conductive layer (6b) on the inside of the tank. Also claimed is a tank with an inner lining as above, in which the conductive layer (6b) is earthed.
Patent EP-0810981-B1 (EP)
Inventor: HUIJS MATHIJS JOHANNUS ANTHONI
IPC: D06M13/02
Filed: 1996-02-20
Granted: 2001-11-21
Abstract: PCT No. PCT/EP96/00718 Sec. 371 Date Nov. 14, 1997 Sec. 102(e) Date Nov. 14, 1997 PCT Filed Feb. 20, 1996 PCT Pub. No. WO96/26164 PCT Pub. Date Aug. 29, 1996The invention relates to a method for manufacturing a product on a basis of mineral wool, including the steps of: i) preparing a phenol-formaldehyde resin, ammonia and a sugar preparation containing aqueous preparation; ii) applying the preparation to the mineral wool; and iii) curing the mineral wool with forming of the product, and to a kit for preparing the mineral wool product, including a container holding the resin preparation and a container holding the sugar preparation.