baber/WOPTO huggingface dataset:
Patent NZ-254326-A (NZ)
Title: An anti-cholesterol egg, its production and use
Inventor: STOLLE RALPH J
IPC: A23L15/00
Filed: 1993-05-28
Abstract: The present invention is directed to the treatment of vascular disorders particularly arteriosclerosis and atherosclerosis in warm-blooded animals. The invention encompasses the ingestion, by warm-blooded animals, of eggs or egg fractions derived from female avians that have been hyperimmunized with specific bacterial antigens or groups of bacterial antigens. The invention is directed to methods of controlling cholesterol levels, lipid deposits, and the development of atheromatous lesions in warm-blooded animals by the ingestion of eggs or fractions thereof produced in female avians hyperimmunized with specific bacterial antigens. The invention is also directed to methods of producing the eggs and to vaccines for hyperimmunization of the female avians.
Patent NZ-267222-A (NZ)
Title: Quinazolinone derivatives and fungicidal compositions
Inventor: BEREZNAK JAMES FRANCIS
IPC: A01N43/84
Filed: 1994-05-10
Abstract: This invention pertains to compounds of Formulae (I), (II), and (III) including all geometric and stereoisomers, N-oxides, agriculturally-suitable salts thereof, agricultural compositions containing them and their use as fungicides, wherein: Q is O or S; and n, R1, R2, R3, R4, R5, R6, R7, R8, and R9 are described in the text.
Patent NZ-267921-A (NZ)
Title: Phenylalanine derivatives prepared by nitration of phenylalanine, followed by reduction and reaction with diphenylcyanocarbonimidate; peptide synthesis
Inventor: HOEGER CARL A
IPC: A61K38/00
Filed: 1994-06-13
Abstract: Methods of making unnatural amino acids are provided which unnatural amino acids can be incorporated into peptides which either inhibit or promote the secretion of gonadotropins by the pituitary gland and inhibit the release of steroids by the gonads. These unnatural amino acids are useful in the synthesis of peptides and have the formula (a):   <IMAGE>   where W is (CH2)n or   <IMAGE>   n is an integer from 1 to 6; j=1, 2 or 3, and preferably, Y is N-CN, X is NH and R2 is alkyl, modified alkyl, alkenyl, alkynyl, aryl or methyl pyridyl. Disclosed are peptides that are analogs of the decapeptide GnRH wherein there is at least one residue of an unnatural amino acid in the 3-, 5-, 6- and/or 8-positions.
Patent NZ-331040-A (NZ)
Title: Taxoids, preparation thereof and pharmaceutical compositions containing them
Inventor: BOUCHARD HERVE
IPC: C07D413/12
Filed: 1997-03-05
Abstract: The specification describes taxoids of above general formula (I), the preparation thereof and pharmaceutical compositions containing them. In general formula (I), Z is a hydrogen atom or a radical of above general formula (II), wherein R1 is an optionally substituted benzoyl radical or a radical R2-O-CO-, where R2 is an alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, bicycloalkyl, optionally substituted phenyl or heterocyclyl radical; R3 is an alkyl, alkenyl, alkynyl, cycloalkyl, phenyl, naphthyl or aromatic heterocyclic radical; R4 is a hydroxy radical or an alkoxy, alkenyloxy, optionally substituted alkynyloxy, alkanoyloxy, alkenoyloxy, alkynyloxy, alkoxyacetyl or alkyloxycarbonyloxy radical, or a cycloalkyloxy, cycloalkenyloxy, arylcarbonyloxy or heterocyclylcarbonyloxy radical; and R5 is an optionally substituted alkoxy radical or a cycloalkyloxy or cycloalkenyloxy radical. The compounds are reported to have remarkable antitumoral and antineoplastic properties.
Patent NZ-334477-A (NZ)
Title: Amino acid ester containing azole antifungals
Inventor: MEERPOEL LIEVEN
IPC: A61K/
Filed: 1998-02-03
Abstract: Disclosed is a compound of formula (I), an N-oxide form, a pharmaceutically acceptable addition salt or a stereochemically isomeric form thereof wherein: A-B forms a bivalent radical of formula -N=CH- (a), -CH=N- (b) or -CH=CH- (c), wherein one hydrogen atom in the radicals (a) and (b) may be repla ced with a C1-6 alkyl-radical and up to two hydrogen atoms in radical (c) may be replaced by a C1-6 alkyl-radical. L represents the acyl moiety of an amino acid D is a radical of formula (D1) and (D2) wherein: X is N or CH R1 is halo R2 is hydrogen or halo Also disclosed is the use and process of preparation of the above compound in the treatment of fungal infections.
Patent NZ-336613-A (NZ)
Title: Oxazoline, imidazoline or thiazoline derivatives useful for inhibiting beta-amyloid peptide
Inventor: THORSETT EUGENE D
IPC: A61K31/41
Filed: 1998-02-27
Abstract: A compound has the formula A-B-D wherein: A is a group of formula (2); R1, R2, R5 and R6 are independently optionally substituted alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, aryl, heteroaryl or heterocyclic; Z is  -CX'X"C(O)-, -T-CH2-C(O)-, -T-C(O)-C(O)-  or -CX'X"-T-C(O)-; X' and X" are independently hydrogen, hydroxy or fluoro, or X' and X" together form an oxo group; T is oxygen, sulphur or -NR3; R3 is hydrogen, acyl, alkyl, aryl or heteroaryl group; m and p are independently is 0 or 1; T' is a bond covalently linking R' to -CX'X"-, oxygen, sulphur or -NR3; W and X are independently -(CR7R7)q-, oxygen, sulphur or -NR8; q is 1 or 2; each R7 and R8 is independently hydrogen, optionally substituted alkyl, cycloalkyl, aryl, heteroaryl, acyl, acyloxy, carboxyl, carboxyl esters or heterocyclic and further, when q is 2, an R7 group on each of the carbon atoms can optionally be fused to form an aryl, heteroaryl, heterocyclic or cycloalkyl group with the ethylene group with the proviso that when unsaturated, the remaining R7 group on each carbon atom participates in the unsaturation; R4 is hydrogen, optionally substituted alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, aryl, heteroaryl or heterocyclic; B is (i) -C(O)-N(H)-CH(R5) or a group of formula 3 or when A is either formula (ii) or (iii) as defined above, then B can also be a covalent bond linking A to D; D is (i) -C(O)Y, (ii) -C(S)Y or (iii) a group of formula 4; Y is optionally substituted alkyl, alkoxy, thioalkoxy or is cycloalkyl, hydroxy, aryl, heteroaryl, heterocyclic, -NR'R", -NHSO2-R8, -NR9NR10R10, -ONR9[C(O)O]zR10, -CR11R11Y' R' and R" are independently hydrogen, optionally substituted alkyl, alkenyl, alkynyl, cycloalkyl, aryl, heteroaryl or heterocyclic provided that one of R' or R" is hydroxy or alkoxy, or R' and R" are joined to form an optionally substituted cyclic group optionally containing 1 to 2 additional heteroatoms of oxygen, sulphur or nitrogen; R9 is hydrogen or alkyl; each R10 and R11 is independently hydrogen, optionally substituted alkyl, alkenyl, cycloalkyl, aryl, heteroaryl or heterocyclic; z is 0 or 1; Y' is hydroxyl, amino, thiol, optionally substituted alkoxy or thioalkoxy, -OC(O)R9, -SSR9 or -SSC(O)R9; A*, together with -C=N-, forms a heterocyclic group which is optionally fused to form a bi- or multi-fused ring system with one or more ring structures selected from optionally substituted cycloalkyl, cycloalkenyl, heterocyclic, aryl or heteroaryl group limited by the provisos listed in the specification. A pharmaceutical composition thereof is useful for inhibiting the cellular release and/or synthesis of b-amyloid peptide, preventing the onset of Alzheimer's disease or inhibiting further deterioration in the condition.
Patent NZ-501838-A (NZ)
Title: Retentate chromatography and protein chip arrays with applications in biology and medicine
Inventor: HUTCHENS T WILLIAM
IPC: G06F19/00
Filed: 1998-06-19
Abstract: This invention provides methods of retentate chromatography for resolving analytes in a sample. The methods involve adsorbing the analytes to a substrate under a plurality of different selectively conditions, and detecting the analytes retained on the substrate by laser desorption spectrometry.   The different selectivity conditions can comprise either different adsorbents, different eluants, or both. The methods are useful in biology and medicine, including clinical diagnostics and drug discovery.
Patent NZ-506175-A (NZ)
Title: Hydroformed hose fitting and die for preparation
Inventor: JUEDES MARVIN
IPC: B21D26/033
Filed: 1999-01-08
Abstract: A hose assembly comprising a unitary hose fitting (10) of hydroformed metal is disclosed. The fitting has at least one hydroformed metal barb without loss of structural rigidity and integrity of the fitting (10). Also, the fitting is said to be from a stock void of brazing and without a machine line. The hose assembly also comprises a hose functionally and dimensionally compatible with said hose fitting (10). The hose connects with the hose fitting (10) by engaging with the hydroformed barb.
Patent NZ-506964-A (NZ)
Title: Trivet to support hot cookware over protected surface with pairs of end and middle supports being adjustable to alter spacing between each portion of respective pair
Inventor: KARI KATHY
IPC: A47G23/00
Filed: 1999-02-26
Abstract: An adjustable trivet has two substantially identical components slideably coupled to permit use with various size cookware is provided. Each component is equipped with an edge support having affirmative retaining means, a middle support having affirmative retaining means, and an extension for connecting the complementing supports. The adjustability feature provides greater support in the central area of larger containers, while moving the support toward the ends of the container as the size decreases.
Patent NZ-507508-A (NZ)
Title: Use of a system allowing the expression of one or two neurotrophic factors to treat amyotrophic lateral sclerosis
Inventor: MALLET JACQUES
IPC: A61K48/00
Filed: 1997-09-10
Abstract: The use of neurotrophin-3 (NT3) expression system for the preparation of pharmaceutical composition to treat amyotrophic lateral sclerosis (ALS) by intravenous administration.  .The expression system expresses consists of two expression cassettes, one coding for NT3 and the other coding for a different neurotrophic factor, chosen from GDNF, CNTF and BDNF.  Both expression cassettes are under the control of a unique transcriptional promoter (bicistronic unit).  In another preparation, riluzole and the expression system is used in the preparation of a medicament for the treatment of ALS
Patent NZ-507999-A (NZ)
Title: Control circuit for solenoid valve
Inventor: JANSSEN ERIC P
IPC: F16K31/08
Filed: 2000-07-03
Abstract: A circuit for controlling a valve 10 includes a solenoid 14 having a coil 56 and a permanent magnet 90.  A pair of switching circuits is connected to the first and second ends of the coil.  When the first switching circuit is activated, current passes through the coil in one direction to move the permanent magnet in a first axial direction.  When the second switching circuit is activated, current passes through the coil in a second direction to move the permanent magnet in a second axial direction.
Patent NZ-515762-A (NZ)
Title: Method of producing a heparin-binding protein by expressing it in a mammalian cell that can be cultured in anaerobic conditions
Inventor: FLODGAARD HANS JAKOB
IPC: C12N5/10
Filed: 2000-04-28
Abstract: A method for producing a mammalian heparin-binding protein in a mammalian cell that can be cultured under anaerobic conditions after introducing a nucleic acid encoding as heparin-binding protein into said cell with comprising (a) introducing into said mammalian cell a nucleic acid encoding said heparin-binding protein; (b) culturing the cell of step (a) under conditions conducive to expression of said HBP; and (c) recovering said HBP from the culture medium. Furthermore, the invention relates to the recombinant mammalian cell used in the method.
Patent NZ-519722-A (NZ)
Title: Treatment of diabetic ulcers
Inventor: WOOD RALPH E
IPC: A61P17/02
Filed: 2001-01-11
Abstract: A method of treating a non-human patient suffering from diabetic ulcers, such as foot ulcers, which comprises treating said non-human patient with an effective amount of a cGMP PDE5 inhibitor, such as sildenafil, or a pharmaceutical composition thereof. Also disclosed is the use of a cGMP PDE5 inhibitor, such as sildenafil, for the manufacture of a pharmaceutical composition for the treatment of diabetic ulcers, such as foot ulcers.
Patent NZ-520283-A (NZ)
Title: Use of enoxaparin, a low molecular weight heparin, for the preparation of medicaments containing between 5 and 280 mg for the treatment of cerebral ischaemia
Inventor: VERONIQUE MARY
IPC: A61P9/10
Filed: 2001-01-03
Abstract: The use of enoxaparin (Lovenox(r), Clexane(r)), a low-molecular weight heparin, for treating cerebral ischemia is described, wherein the enoxaparin makes it possible to reduce cerebral ischemic sequelae.
Patent NZ-522911-A (NZ)
Title: A composition for reducing dental plaque and/or preventing root caries comprising an exogenous lactic acid bacterial strain
Inventor: COMELLI ELENA-MARIA
IPC: A61K8/99
Filed: 2001-05-30
Abstract: Described is the use of a lactic bacteria strain that is exogenous to the oral microflora, which has been selected for its ability to adhere the pellicle of the teeth and to produce a growth inhibition factor.  The preparation of a composition intended for reducing dental plaque and for treating or preventing root caries and other diseases related to Actinomyces naeslundii in mammals is also described.
Patent NZ-523397-A (NZ)
Title: Reciprocating saw
Inventor: WHEELER THOMAS J
IPC: B23D49/16
Filed: 2002-12-24
Abstract: A reciprocating saw (10) includes a carrier (16) operable to cooperate with a motor to translate rotational movement of the motor into reciprocal linear actuation of a saw blade (20). A carrier (16) is slidably disposed within the housing (14) and includes a first portion adapted to receive a saw blade (20) and a second portion having a slot therethrough. A rotatable element is fixed for rotation about an output shaft of the motor. A follower operably interconnects the carrier (16) and the rotatable element wherein rotation of the rotatable element provides reciprocal linear motion of the carrier (16) whereby the follower follows a reciprocal linear path within the slot.
Patent NZ-526576-A (NZ)
Title: Flat water hose and hose connectors for flat water hose
Inventor: LIN PEI-YING
IPC: F16L11/22
Filed: 2003-06-20
Abstract: A hose connector on one end of a flat water hose with a plurality of water passages arranged in parallel and with a fitting. The hose connector comprising of a mounting base member (20) with a mounting hole (21) in one end and a connecting member (31) on the other end to secure it to the plug member (41), which consists of a hollow shell with a plurality of tubular plug rods in fluid communication with the water passages of the flat water hose. The connecting member has at least one locating notch (311) and is engaged with the locating block (411) of the plug member.
Patent NZ-526898-A (NZ)
Title: Scaffold bracket
Inventor: HARD NORMAN ALLAN
IPC: E04B1/18
Filed: 2003-07-09
Abstract: A bracket assembly (100) for rigidly connecting an elongate upright member (1); a first elongate lateral member (2), and a second elongate lateral member (3), comprises: a first channel portion (4) configured for receiving the upright member (1), a second channel portion (5) configured for receiving the first lateral member (2), a third channel portion (6) configured for receiving the second lateral member (3), wherein locking means (23) are fixed to at least the first channel portion (4) for releasably clamping the upright member (1) to the bracket (100) and the first (4), second (5)and third channel (6) portions are permanently fixed together.
Patent NZ-527940-A (NZ)
Title: Leporipox-based vector vaccines
Inventor: SPIBEY NORMAN
IPC: A61K48/00
Filed: 2002-03-07
Abstract: The use of a live, recombinant leporipox virus comprising exogenous DNA, which is operably linked to at least one expression control element and which is incorporated in a non-essential region of the virus genome, in the manufacture of a vector vaccine for the treatment and/or prophylaxis of infectious diseases in non-lepori species is disclosed. The disclosure furthermore relates to a live, recombinant leporipox virus comprising exogenous DNA operably linked to at least one expression control element and incorporated in a non-essential region of the virus genome characterized in that said exogenous DNA encodes at least one antigen of a non-lepori pathogen. Due to its restricted host-range the recombinant leporipox virus is non-pathogenic in non-susceptible hosts such as non-lepori vertebrates. Vaccination with said recombinant leporipox virus induced an antigen or immunogenic response in the vaccinated non-lepori host even though productive replication of the virus was not observed in the host. The vector vaccine disclosed is for the treatment and/or prophylaxis of infectious diseases in felines or canines.
Patent NZ-533137-A (NZ)
Title: Spacer for use electric fence insulator, with passageway for fasteners
Inventor: POWELL KERRY JOHN
Filed: 2004-05-24
Abstract: A spacer 1 for an electric fence insulator 6 is disclosed having apertures 2, allowing it to be attached by fasteners to a support (not shown). Typically, the spacer 1 is nestable with respect to the insulator 6 and the fasteners pass through both insulator 6 and spacer 1.
Patent NZ-533609-A (NZ)
Title: kayak with aperture between upper and lower skins to accommodate removable propulsion device
Inventor: HOPKINS ALAN GERARD
IPC: B63B35/71
Filed: 2002-11-29
Abstract: A watercraft comprising a shell having an upper skin adapted to support at least one person, a lower skin (15) defining a hull (23) for contact with the water, an aperture extending through the upper and lower skin and defined by a sidewall enclosure between the lower skin (15) and the upper skin to maintain the integrity of the shell, wherein the aperture removably secures a propulsion means (31) for propelling the watercraft, such that a cavity within the shell remains watertight to allow for practical functioning when the propulsion means is removed. The watercraft may also include an outrigger (not shown) on either side for greater stability in the water. (61) Addition to 533609
Patent NZ-538021-A (NZ)
Title: Benzothiazole derivatives having beta-2-adrenoreceptor agonist activity
Inventor: CUENOUD BERNARD
IPC: A61P17/06
Filed: 2003-08-08
Abstract: Compounds of Formula (I) in free or salt or solvate form, wherein X has the meaning indicated in the specification, are useful for treating conditions that are prevented or alleviated by activation of the ss2-adrenoreceptor. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.
Patent NZ-539574-A (NZ)
Title: A method and a device for making images of the quantum efficiency of the photosynthetic system with the purpose of determining the quality of plant material and a method and a device for measuring, classifying and sorting plant material
Inventor: JALINK HENDRIK
IPC: G01N33/483
Filed: 2003-10-31
Abstract: A method for determining the quality of plant material is achieved by determining a chlorophyll fluorescence image of said plant material. The plant material is irradiated with a beam of electromagnetic radiation comprising one or more such wavelengths that at least a part of the chlorophyll present is excitated by at least a part of the radiation. The beam of electromagnetic radiation has such a shape that only a small part of the plant material is irradiated, and the beam is moved over the plant material such that a larger part of the plant material is measured. The fluorescence radiation originating from the plant material associated with the chlorophyll transition, is measured with an imaging detector for obtaining a chlorophyll fluorescence image. In any order, during a certain duration of time several fast scans are made over the plant material with the electromagnetic beam for obtaining a chlorophyll fluorescence image Ffast, and during a certain duration of time a slow scan is made over the plant material with the electromagnetic beam for obtaining a chlorophyll florescence image Fslow, and subsequently the characteristic chlorophyll fluorescence image that is a measure for the efficiency of the photosynthetic system of plant material is calculated from the chlorophyll fluorescence images Ffast and Fslow.
Patent NZ-540067-A (NZ)
Title: A purified preparation of antibodies that specifically bind to a high mobility group box protein (HMGB) B box but do not specifically to non-B box epitopes of HMGB
Inventor: NEWMAN WALTER
IPC: C07K14/47
Filed: 2003-11-20
Abstract: A purified preparation of antibodies that specifically bind to a high mobility group box protein (HMGB) B box but do not specifically bind to non-B box epitopes of HMGB, wherein said antibodies can inhibit release of a proinflammatory cytokine from a cell treated with HGMB, wherein said HMGB B box is selected from HMG1L5 B box, an HMG1L1 B box, an HMGB1L4 B box, and an HMGB box polypeptide of BAC clone RP11-395A23. Also disclosed is the use of the purified preparation of antibodies for the manufacture of a medicament for a condition characterized by activation of an inflammatory cytokine cascade.
Patent NZ-541290-A (NZ)
Title: Nutritional supplement composition containing a mixture of whey protein, amino acids, and other beneficial constituents, and a method for making the composition in a nutritionally compact, easy-to-use form
Inventor: DOPSON MINTER H
IPC: A23L33/00
Filed: 2003-10-24
Abstract: A nutritional supplement composition comprising a mixture of whey protein and amino acids, and a method for making the composition in a nutritionally compact, easy-to-use form is described. The composition is made by processing a mixture of whey protein, amino acids, minerals, vitamins, and other selected ingredients at an appropriate temperature and pH. By adjusting the pH of the mixture to within the approximate range of 2.5 - 5.0, and by processing at an appropriate temperature, it is possible to obtain a gel composition that contains a large fraction of whey proteins (and other beneficial constituents) in readily bioavailable form. The composition can be packaged into conveniently-sized containers that are as easy to store or transport as they are easy to use.
Patent NZ-543194-A (NZ)
Title: Oral hygiene apparatuses
Inventor: BOWSHER M WILLIAM
IPC: A61C15/04
Filed: 2004-03-25
Abstract: A dental hygiene apparatus (10) for enabling a flossing of teeth. The apparatus includes a dispensing member (12) in the form of an annular dispensing ring with an aperture for receiving a finger of a user, and an accumulating member (14), which can also include an aperture for receiving a finger of a user. Activating switches (18, 20, 254) can selectively enable a dispensing of dental floss from the dispensing member and a retraction of dental floss relative to the accumulating member. A bobbin (38) within the accumulating member can be rotated by a coil spring (32) that can be rewound. The apertures in the rings can be varied. A floss retaining member (12, 14, 250) can alternatively be retained by a ring (260), an opposed hook arrangement (268), or any other arrangement coupled to the dispensing member. Dental floss can be dispensed from a distal end of a post (266). The dental hygiene apparatus can further include as part of a unified system a finger shield arrangement (150), which can comprise first and second tubular members (152, 154).
Patent NZ-546174-A (NZ)
Title: Propagation agent and propagation methods for natural killer cell
Inventor: KUHARA TETSUYA
IPC: G01N33/50
Filed: 2005-09-07
Abstract: Disclosed is a drug combination for proliferating non-human animal natural killer cells, which comprises lactoferrin as a first agent and polyinosinic-polycytidylic acid as a second agent, wherein the first agent comprises doses for 7 days in an amount of 10 to 2000 mg/day/kg body weight, and the second agent comprises one dose at 5 days after beginning of administration of the first agent in an amount of 10 to 1000 µg/day/kg body weight.