baber/WOPTO huggingface dataset:
Patent PT-1375076-E (PT)
Inventor: DROSTE MANFRED
IPC: B25D11/06
Filed: 2003-06-19
Abstract: An electrically powered hammer comprising a hammer housing (10) with a hollow cylindrical spindle (4) mounted within it. The hammer has a tool holder arrangement (36) located at a forward end of the spindle for releasably holding a tool or bit (34) within the spindle so as to enable limited reciprocation of the tool or bit within the spindle. An air cushion hammering mechanism is mounted within the spindle for generating repeated impacts on the tool or bit which hammering mechanism includes a piston (24). A motor is mounted within the housing for rotatingly driving an intermediate shaft (6) rotatably mounted in the housing. A wobble drive arrangement (12, 16, 18, 20) reciprocatingly drives the piston (24) and includes a wobble sleeve (12) rotatably mounted on the intermediate shaft (6). A mode change element (72) is selectively engageable, by movement along the intermediate shaft, with a set of drive teeth (74) provided on the intermediate shaft and a set of driven teeth provided on the wobble sleeve, such that when the mode change element (72) is engaged with both sets of teeth it transmits rotary drive from the intermediate shaft (6) to the wobble sleeve (12) so that the wobble sleeve arrangement reciprocatingly drives the piston (24). The mode change ring (72) is formed integrally with at least one axial stop surface (86) and the or each axial stop surface (86) is engageable with a cooperating end stop surface formed integrally with one of the intermediate shaft and the wobble sleeve to limit the movement of the mode change element along the intermediate shaft. <IMAGE>
Patent PT-1405861-E (PT)
Title: Analogs of parathyroid hormone
Inventor: DONG ZHENG XIN
IPC: A61P19/00
Filed: 1996-07-03
Abstract: Peptide variants of fragment (1-34) of parathyroid hormone, in which at least one of the amino acid residues at positions 7, 11, 23, 24, 27, 28 and 31 is cyclohexylalanine, or at least one of the amino acid residues at positions 3, 16, 17, 18, 19 and 34 is  alpha -aminoisobutyric acid; or, alternatively, at least the amino acid residue at position 1 is  alpha , beta -diaminopropionic acid, the amino acid residue at position 27 is homoarginine, or the amino acid residue at position 31 is norleucine.
Patent PT-1495119-E (PT)
Title: Method and apparatus for extracting nucleic acids from a complex mixture
Inventor: HALLIER-SOULIER SYLVIE
IPC: G01N30/88
Filed: 2003-04-09
Abstract: The invention relates to a method for extracting nucleic acids of microorganisms contained in a complex mixture, particularly a food mixture, comprising at least the following steps: the mixture (10) is clarified; the microorganisms are retained on a filtering cartridge (12); said microorganisms are lysed (14); the nucleic acids are recovered (16), concentrated, and purified (18). The invention also relates to a filtering cartridge and an apparatus used for carrying out the inventive extraction method. Also disclosed is a device for extracting, detecting, and if necessary quantifying the nucleic acids of microorganisms contained in a complex mixture.
Patent PT-1523330-E (PT)
Title: Vaccine against salmonid rickettsial septicaemia based on arthrobacter cells
Inventor: SALONIUS KIRA
IPC: A61K45/00
Filed: 2003-07-14
Abstract: A vaccine based on live Arthrobacter cells is useful in preventing piscirickettsiosis in fish.
Patent PT-1603941-E (PT)
Title: Inhibitors of extracellular hsp90
Inventor: JAY DANIEL G
IPC: G01N33/50
Filed: 2004-03-09
Abstract: The present invention describes the inhibitors of extracellular Hsp90. The inhibition of extracellular Hsp90 leads to a reduction of the invasiveness of the tumor cells. Furthermore, the invention relates to the use of molecules inhibiting extracellular Hsp90 function for the manufacture of a medicament for the treatment or prevention of invasion and/or metastatic potential of cancer cells.
Patent PT-1610766-E (PT)
Title: Amoxicillin trihydrate
Inventor: GROENENDAAL JAN WILLEM
IPC: A61K9/14
Filed: 2004-03-22
Abstract: The present invention relates to a product of amoxicillin trihydrate, having a free water content of less than 0.1 wt.%, preferably less than 0.07 wt.%, more preferably less than 0.05 wt.%, measured at an equilibrium relative humidity of 30% and at a temperature of 25 °C. The product is advantageously used in mixture with clavulanic acid. The invention also relates to a process for the preparation of the new product.
Patent PT-1636325-E (PT)
Title: Corrosion reduction with amine scavengers
Inventor: STARK JOSEPH L
IPC: C10G7/10
Filed: 2004-05-19
Abstract: Corrosive amine salts in hydrocarbon streams such as desalted crude oil streams can be prevented or avoided by adding certain amine scavenging chemicals to the streams. Suitable amine scavengers include, but are not necessarily limited to, carboxylic anhydrides and copolymers of carboxylic anhydrides, aromatic anhydrides, isocyanates, polyisocyanates, and epoxides. The non-corrosive reaction products of the amines and/or ammonia with these scavengers are preferably oil-soluble, non-basic and thermally stable. The amine scavengers bind up and react with the amines and/or ammonia to keep them from reacting with materials such as acids (e.g. HCl) to form corrosive amine salts.
Patent PT-1644679-E (PT)
Title: Device for treating damp waste
Inventor: LEVASSEUR JEAN-PIERRE
IPC: C05F7/00
Filed: 2004-06-29
Abstract: The material is spread successively in layers forming a moist mass (M). Each layer is mechanically-mixed (4) immediately after spreading, with the immediately-underlying layer : Layers are formed as strips, mixing (4) being carried out along them. Odd numbers of strips are formed; spreading taking place in one direction on a first, then in the opposite direction on the next, and so on to the end, then back to the first. Mixing forms a swathe. The mass is 0.5-3 m high and several meters wide. It is formed in a glasshouse, with five changes of air per hour. Internal recirculation is 10-50 times per hour. Temperature, moisture and gas content of the air are measured, controlling its replacement rate from the results. The material is sewage sludge. Layers are spread and mixed as described, with a frequency between once an hour and once a week. Between several spreading operations, the mass is turned once. An independent claim is included for the plant carrying out the method.
Patent PT-1735345-E (PT)
Title: Processes for preparing eptifibatide and pertinent intermediate compounds
Inventor: HO GUOJIE
IPC: C07D213/71
Filed: 2005-04-08
Abstract: The present invention provides, inter alia, convergent processes for preparing eptifibatide that involve coupling a 2-6 eptifibatide fragment to an activated cysteinamide residue to form a 2-7 eptifibatide fragment, attaching a mercaptopropionic acid residue to the 2-7 eptifibatide fragment through disulfide bond formation, coupling the peptide intramolecularly, and removing the protecting group, to form eptifibatide. The invention further provides products produced by the described processes, novel compounds that can be used as synthetic intermediates for the preparation of eptifibatide, and novel compounds that are structurally similar to eptifibatide.
Patent PT-1810523-E (PT)
Title: Method and products for aligning data between a manager and an agent in a management network
Inventor: HIRSCH LUCIAN
IPC: H04L12/24
Filed: 2005-10-06
Abstract: A method for operating a management network comprising a manager (NMC1,NMC2) and an agent (OMC1), in which the manager and the agent use an object model for intercommunication and by means of this, objects (MOLi, MOLj,k,m) are assigned object classes (MOCj,MOCk, MOCm) and with which the manager sends to the agents a request for information exchange. The manager receives information for the request from the agent and exclusively for the objects and/or alarms, regarding a change since a given time point (t0,t1,t6). Independent claims are included for the following: (A) A manager in a management network. (B) An agent in a management network. (B) A management network.
Patent PT-1685965-E (PT)
Title: Liquid container
Inventor: SEINO TAKEO
IPC: B41J2/175
Filed: 2004-03-05
Abstract: The cartridge (11) has several ink storing bags arranged such that the bags are shifted from each other by partially overlapping the adjacent bag along the base of ink cartridge case (13). The space between adjacent ink outlet ports (45) is gradually increased due to the flow of ink towards the center of outlet port. Independent claims are also included for the following: (1) ink ejection device; (2) ink cartridge case.
Patent PT-1879901-E (PT)
Title: Pyrrolobenzodiazepines
Inventor: HOWARD PHILIP WILSON
IPC: A61P35/00
Filed: 2006-04-21
Abstract: Compounds of the formula I: or solvate thereof, wherein: R2 is an optionally substituted C5-20 aryl group; R6 and R9 are independently selected from H, R, OH, OR, SH, SR, NH2, NHR, NRR', nitro, Me3Sn and halo; where R and R' are independently selected from optionally substituted C1-12 alkyl, C3-20 heterocyclyl and C5-20 aryl groups; R7 is selected from H, R, OH, OR, SH, SR, NH2, NHR, NHRR', nitro, Me3Sn and halo; R'' is a C3-12 alkylene group, which chain may be interrupted by one or more heteroatoms and/or aromatic rings; X is selected from O, S, or NH; z is 2 or 3; M is a monovalent pharmaceutically acceptable cation; R2', R6', R7', R9', X' and M' are selected from the same groups as R2, R6, R7, R9, X and M respectively, or M and M' may together represent a divalent pharmaceutically acceptable cation.
Patent PT-1940305-E (PT)
Title: Distance-keeping inter-process implant
Inventor: CIUPIK LECHOSLAW FRANCISZEK
IPC: A61B17/70
Filed: 2006-09-01
Abstract: The invention concerns a distance-keeping inter-process implant with a body ending in its posterior part with two opposite-situated resistance protrusions. In the anterior part of the body there are situated at least two wings, at least one of which is a mobile wing connected with the body by an articulated joint. Each wing is provided with at least one guide of the tensioning band. The articulated joint between the mobile wing and the body is formed by the mutually collaborating shaped surface of the. wing (and the shaped surface of the body and is usefully secured by the pin that constitutes the axis of rotation of the mobile wing. In an alternative version of the implementation of the implant, the mobile wing connected with the body is provided with at least one arm situated with respect to the wing at the angle α amounting to from 30° to 150°.
Patent PT-2066659-E (PT)
Title: Substituted sulfonamide derivatives
Inventor: CHRISTOPH THOMAS
IPC: C07D401/12
Filed: 2007-09-27
Abstract: N-heterocyclic sulfonamide derivatives with aminocarbonyl-methoxymet hyl or aminocarbonyl-methoxyethyl groups on the ring carbon adjacent to the sulfonamide nitrogen atom are new. Substituted sulfonamide derivatives of formula (I) in the form of racemates, enantiomers or diastereoisomers of the bases, mixtures of the last two, and/or their salts with physiologically-tolerable acids are new. n : 0, 1, 2 or 3; m : 1 or 2; R 1>aryl or heteroaryl; R 2a-c>, R 3>, R 4>H, or these groups plus an adjacent group may form a 5- or 6-membered ring (saturated or unsaturated, optionally substituted and containing N or O as hetero-atoms; R 5> and R 6> together form (a) a 4- to 8-membered non-aromatic ring (optionally condensed with a 4- to 10-membered aromatic, saturated or unsaturated ring, with either or both rings being substituted or condensed with a basic residue and optionally substituted with other basic residues selected from 1-6C alkyl, 1-3C alkoxy, 3-8C cycloalkyl, : O, aralkyl or aryl), or (b) a 4- to 8-membered ring containing another N or O atom and optionally substituted with a basic or non-basic residue, the ring N-atom being optionally substituted also with 1-6C alkyl, aryl or aralkyl if the basic or non-basic residue is not attached to the ring via the hetero-atom, or (c) R 5>= H, 1-6C alkyl, 3-8C cycloalkyl, aryl or aralkyl and R 6>= aryl 3-8C cycloalkyl or an aryl or 3-8C cycloalkyl group linked via a 1-3C alkyl chain, the aryl or cycloalkyl group being optionally condensed with a 5- to 10-membered optionally unsaturated ring (optionally containing hetero-atom(s)) and substituted with a basic residue (or this alkyl substitution may be on the 1-3C alkyl bridge), or (d) R 5>= H, 1-6C alkyl, 3-8C cycloalkyl, aryl or aralkyl and R 6>= 4-8C heterocyclyl (optionally linked via a 1-3C alkyl chain), optionally substituted on one or two ring members with a basic or non-basic residue, or (e) R 5>, R 6>= H, aralkyl or optionally branched, optionally substituted 1-10C alkyl containing 1-3 N atoms (R 5> and R 6> cannot both be H), or (f) R 5>= H, alkyl, cycloalkyl, aryl or aralkyl as above and R 6>= a basic heteroaryl group, optionally linked via 1-4C alkylene and optionally substituted, in which the 1-4C chain may also be substituted with a basic residue; . Independent claims are also included for (1) a method for the production of (I) by reacting carboxylic acids of formula (L) with prim. or sec. amines of formula R 5>R 6>NH (M) in presence of dehydrating agents such as sodium or magnesium sulfate, phosphorus pentoxide or reagents such as CDI, DCC, TBTU and EDCI, and in presence of HOAt or HOBt and an organic base, e.g. DIPEA or pyridine, in a solvent such as THF, dichloromethane, diethyl ether, dioxan, DMF or acetonitrile (2) drugs containing (I), optionally with suitable additives, auxiliary substances and/or other active ingredients. [Image] [Image]
Patent PT-2336359-E (PT)
Title: 1l1rl-1 as a cardiovascular disease marker
Inventor: RICHARD T LEE
IPC: C07H21/00
Filed: 2003-05-09
Abstract: This invention pertains to methods and compositions for the diagnosis and treatment of cardiovascular conditions. More specifically, the invention relates to isolated molecules that can be used to diagnose and/or treat cardioivascular conditions including cardiac hypertrophy, myocardial infarction, stroke, arteriosclerosis, and heart failure.
Patent PT-575875-E (PT)
Inventor: ALBIZZATI ENRICO
IPC: C08F4/659
Filed: 1993-06-16
Abstract: A catalyst for the polymerization of olefins comprises the product obtained by contacting:   (A) a titanium, zirconium or hafnium mono- or bis-cyclopentadienyl compound, this latter optionally containing a bridging group which links the two cyclopentadienyl compounds; (B) an alkyl aluminium wherein at least one alkyl is different from a straight alkyl; and   (C) water. The molar ratio aluminium/water is higher than 1:1 and lower than 100:1.
Patent PT-745221-E (PT)
Inventor: GIANNOBILE WILLIAM V
IPC: G01N33/50
Filed: 1995-01-13
Abstract: A method of diagnosing severity of periodontal disease or peri-implant disease in a human patient, involving a) obtaining a sample of tissue or gingival crevicular or other fluid from the mouth of said patient, or a blood or urine sample from the patient, and b) measuring a pyridinoline crosslinked compound in the sample as a measure of severity of disease.
Patent PT-751774-E (PT)
Inventor: DAGE RICHARD C
IPC: A61P9/10
Filed: 1995-02-28
Abstract: PCT No. PCT/US95/02448 Sec. 371 Date Nov. 24, 1997 Sec. 102(e) Date Nov. 24, 1997 PCT Filed Feb. 28, 1995 PCT Pub. No. WO95/25519 PCT Pub. Date Sep. 28, 1995The present invention relates certain mercaptoacetylamide disulfide derivatives of the formula useful in treating patients suffering from hypertriglyceridemia, atherosclerosis and hypercholestrolemia.
Patent PT-846199-E (PT)
Inventor: GERMGARD ULF
IPC: D21C9/10
Filed: 1996-08-09
Abstract: A method of chlorine-free bleaching of pulp where metals are removed by means of a chelating agent. The chelating agent is admixed to the pulp in at least two subsequent mixing steps without intermediate washing. The stay-time between the mixing steps shall be less than 15 minutes, and the pulp is washed after the last mixing step.
Patent PT-865594-E (PT)
Inventor: NYSTROM BERNT
IPC: F24F3/052
Filed: 1996-11-28
Abstract: PCT No. PCT/SE96/01562 Sec. 371 Date Jun. 5, 1998 Sec. 102(e) Date Jun. 5, 1998 PCT Filed Nov. 28, 1996 PCT Pub. No. WO97/21963 PCT Pub. Date Jun. 19, 1997A dual-channel mixing box (1) is arranged in series with other such mixing boxes in order to regulate the temperature of the air in one room each or in several rooms. Each mixing box is provided with supply pipes (3,4) running through it, in which air of different temperatures flows. Each supply pipe is provided with a damper (5), the dampers in a mixing box (1) being adjustable by means of a motor-operated rod (6) so that when one damper is moved in closing direction, the other damper is moved in opening direction, and vice versa. A mixing chamber (11) for the air from both supply pipes is formed between the supply pipes (3,4). The mixing chamber is in controllable communication with one or two outlet chambers (12) communicating through pipes with the room(s) in which the temperature is to be regulated via the mixing box in order to supply a mixture of air with the desired temperature. The controllable connection between the mixing chamber and each outlet chamber comprises a screw mechanism (9) arranged in each supply pipe in order to clamp the supply pipe to form a gap (10) between the chambers.
Patent PT-900227-E (PT)
Inventor: DAVIS EDWARD MARK
IPC: C07F9/6506
Filed: 1997-04-01
Abstract: PCT No. PCT/US97/05307 Sec. 371 Date Oct. 15, 1998 Sec. 102(e) Date Oct. 15, 1998 PCT Filed Apr. 1, 1997 PCT Pub. No. WO97/41132 PCT Pub. Date Nov. 6, 1997An improved process for the preparation of a diester of phosphoric acid 2,5-dioxo-4, 4-diphenyl-imidazolidin-1-ylmethyl ester is described where an alkali metal phosphate is treated with a 3-(chloromethyl)- or 3-(bromomethyl)-5,5-diphenyl-2,4-imidazolidinedione to afford the desired product, as well as valuable intermediates used in the process.
Patent PT-985043-E (PT)
Title: Lactic acid bacterial starter cultures and compositions thereof
Inventor: NILSSON DAN
IPC: C12N1/21
Filed: 1998-05-25
Abstract: Methods of enhancing the growth rate and/or controlling the metabolic activity of lactic acid bacteria and of improving the shelf life and/or the quality of an edible product using lactic acid bacterial organisms which are defective in their pyruvate metabolism. There is also provided starter culture compositions comprising such defective lactic acid bacteria as helper organisms and lactic acid bacterial starter culture strains. Useful helper organisms are Lactococcus strains which are defective with respect to pyruvate formate lyase (Pfl) and/or lactate dehydrogenase (Ldh) activity. The helper organisms may overexpress a gene coding for an NADH regenerating enzyme such as NADH oxidase encoded by nox gene.
Patent PT-1141640-E (PT)
Inventor: KAISER MARIO
IPC: F25D25/02
Filed: 1999-12-10
Abstract: A refrigerating unit includes a cooling chamber, a storage compartment removably guided within the chamber as far as a closing position, and a disengagement device. The chamber has a parallel-guide disposed on its sides. The guide has a mating toothed configuration, two rollers rigidly coupled, lying opposite each other, and each having an external toothed configuration with a pitch circle diameter to be rollingly coupled to the mating toothed configuration. The guide has an end section reached by the rollers near the closing position. One of the mating toothed configuration and the rollers is positionally fixed. The disengagement device disengages the mating toothed configuration from the external toothed configuration of the rollers and is at the end section and has a disengagement length compensating for oblique positioning of the compartment in and counter to a movement direction arising from an offset of the rollers along the mating toothed configuration.
Patent IE-840022-L (IE)
Title: Pyrimidines.
IPC: C07F9/6512
Filed: 1984-01-06
Abstract: Heterocyclic compounds of the formula <IMAGE> I wherein R1, R2, R3, R4, R5 and X are as defined hereinafter, process for their preparation, as well as pesticidal compositions containing these compounds as the active ingredient and methods for using the pesticidal compositions for the control of pests are described.
[US4584295A]
Patent IE-36071-L (IE)
Title: Furylmethyl - benzomorphane derivatives
IPC: C07D231/26
Filed: 1972-02-08
Abstract: 1384115 Furylmethyl-benzomorphan derivatives BOEHRINGER INGELHEIM GmbH 7 Feb 1972 [8 Feb 1971 25 Feb 1971] 5594/72 Heading C2C [Also in Division A5] Novel compounds of the general formula (wherein R is H, CH 3 or CH 3 CO; R 1 is H, CH 3 , C 2 H 5 , n- or iso-C 3 H 7 or C 4 H 9 ; R 2 is H or CH 3 or C 2 H 5 , and R 3 is H, CH 3 and C 2 H 5 ) and acid addition salts thereof, may be obtained (a) by reducing a compound of Formula II in which Z<SP>1</SP> is halogen, -CHO, -CH 2 OH, -COCH 3 or -CH 2 CHO, or by decarboxylating a compound of Formula II in which Z<SP>1</SP> is -COOH; (b) by methylating or acetylating a compound of Formula I in which R is H; (c) by dealkylating, dearylating or deacylating a compound of Formula I in which R is alkyl, aralkyl or acyl; (d) by reacting a compound of the Formula (VI) in which R 4 is H, alkyl, aralkyl or acyl, with a compound of the Formula (VII) where X is a halogen atom or an alkyl- or arylsulphonyloxy group and Z represents R 3 or Z<SP>1</SP>, and where necessary converting Z or R 4 , (e) by reacting a compound of Formula VI with formaldehyde and a compound of Formula VIII (f) by reacting a compound of Formula VI with a compound of Formula IX in the presence of catalytically activated hydrogen or formic acid, (g) or by reducing a compound of the Formula X and where necessary converting Z into R 3 , dealkylating, dearylating or deacylating R 4 and subseqently, if desired methylating or acetylating to form a compound of Formula I wherein R is methyl or acetyl.
[GB1384115A]
Patent IE-830208-L (IE)
Title: Preservative and fixative preparations for biological¹systems
IPC: G01N33/48
Filed: 1983-02-03
Abstract: A fixative composition for histological, cytological, immunological and proteinaceous preparations comprising a mixture of pyrrolid-2-one, a polyol, a urea and a zinc salt of a non-oxidizing organic or inorganic acid. Also disclosed are devices utilizing such compositions.
[US4493821A]
Patent IE-33207-L (IE)
Title: Pharmaceutical compositions containing diazacarbazole
IPC: C07D239/42
Filed: 1969-03-28
Abstract: 1,262,864. Antiviral compositions. GLAXO LABORATORIES Ltd. 25 March, 1969 [29 March, 1968], No. 15328/68. Heading A5B. [Also in Division C2] Therapeutic compositions for oral, topical, rectal intravaginal or parenteral administration contain as antiviral agent a 1, 3- or 1, 8-diazacarbazole (or their physiologically acceptable salts), together with a carrier, excipient and/or further medicinal agent; the latter may be a steroid such as betamethasone-21-phosphate or an antibiotic such as tetracycline.
[GB1262864A]
Patent IE-40847-L (IE)
Title: Pyridazine derivatives
IPC: A61P9/12
Filed: 1974-03-04
Abstract: 6-SUBSTITUTED 3-CARBETHOXYHYDRAZINOPYRIDAZINES OF THE GENERAL FORMULA:
[US3925381A]
Patent IE-780507-L (IE)
Title: 4-acylaminophenyl-ethanolamines
IPC: C07C239/00
Filed: 1978-03-13
Abstract: Compounds of the formula <IMAGE> wherein R1 is hydrogen, halogen or cyano; R2 is fluorine, cyano, trifluoromethyl, nitro or alkyl of 1 to 4 carbon atoms; R3 is alkoxy of 1 to 5 carbon atoms, alkenyloxy of 2 to 5 carbon atoms, aryloxy of 6 to 10 carbon atoms, aralkoxy of 7 to 11 carbon atoms, or -NR5R6, where R5 and R6 are each hydrogen, alkyl of 1 to 5 carbon atoms, alkenyl of 2 to 5 carbon atoms, aryl of 6 to 10 carbon atoms or aralkyl of 7 to 11 carbon atoms; and R4 is cycloalkyl of 3 to 5 carbon atoms or alkyl of 3 to 5 carbon atoms; and non-toxic, pharmacologically acceptable acid addition salt thereof. The compounds as well as the salts are useful as analgesics, uterospasmolytics and antiasthmatics.
[US4214001A]