baber/WOPTO huggingface dataset:
Patent CA-2698755-A1 (CA)
Inventor: KHAN SHAHARYAR
IPC: A61K31/66
Filed: 2008-09-08
Abstract: Compositions and methods for treating mitochondrial disorders are provided.  The compositions include compounds having a mitochondrial targeting moiety, for example a lipophilic cation. Certain compounds are effective for increasing the ratio of phosphocreatine/creatine in a host, for example a mammal. Other compounds decrease the ratio of phophocreatine/creating in a host. An exemplary compound is defined by the following structure (Formula Ia): wherein R1 is H or phosphate and the double bond is between N1 and C1 or between N2 and C1; R2 is a mitochondrial targeting moiety; R3 an alkyl, alkylaryl, alkylheteroaryl spacer group, a cleavable linker, or absent; R4 is H or an alkyl, aryl, or heteroaryl group; and R5 is alkyl, aryl, or heteroaryl; or N1 C1, and N3 together form a heterocyclic ring containing at least 5 atoms, wherein N1, N3, and R1-R5 are as defined above, or N3 and R5 together form a heterocyclic ring containing at least four atoms; or a pharmaceutically acceptable salt or prodrug thereof.
Patent CA-2701328-A1 (CA)
Inventor: GASPERS HEINZ-JUERGEN
IPC: F16D65/12
Filed: 2008-07-15
Abstract: The invention relates to a brake disc (100) having a face-end friction ring portion (10) on which a brake disc cam (17) provided with a cam bore (20) is moulded. In order to further develop the brake disc (100) in such a manner that adequate safeties with respect to the permissible material values on brake discs (100) for high-energy application cases are provided and material stresses in the region of the brake disc cam (17) of the brake disc (100), which are caused through temperature differentials within the brake disc (100) as a consequence of high braking energy inputs, are reduced, the invention proposes that the brake disc cam (17) comprises two arm parts (18, 19) which extend spaced from each other from the face-end friction ring portion (10) in the direction of the cam bore (20) and converge in front of the cam bore (20).
Patent CA-2703125-A1 (CA)
Inventor: GUERIN DAVID J
IPC: C07D471/04
Filed: 2008-10-21
Abstract: The present invention relates to pyrazine substituted pyrrolopyridines which are inhibitors of JAK kinases (JAK1, JAK2, JAK3 and/or TYK2) and/or PDK1 and are thus useful for the treatment of myeloproliferative disorders or cancer.
Patent CA-2706872-A1 (CA)
Title: Intermediates for the preparation of lipoxin a4 analogs
Inventor: BAUMAN JOHN G
IPC: A61P37/00
Filed: 2002-11-05
Abstract: This invention is directed to lipoxin A4 analogs of the following formulas (I) and (II), wherein R1, R2, R3, R4 and R5 are described herein. These analogs are useful in treating inflammatory and autoimmune disorders in humans. These analogs are also useful in treating pulmonary or respiratory tract inflammation in humans.   (see formula I); and (see formula II)
Patent CA-2709534-A1 (CA)
Title: Method of preparing amidoamine alkoxylates and compositions thereof
Inventor: STERN ALAN J
IPC: C09K8/36
Filed: 2008-12-19
Abstract: A method of producing an amidoamine alkoxylate is disclosed that involves reacting a triglyceride, a carboxylic acid, or a combination of triglyceride and carboxylic acid with an alkyleneamine to produce an amidoamine and alkoxylating the amidoamine with an alkylene oxide. Also disclosed are amidoamine alkoxylate compositions and their use in agricultural formulations.
Patent CA-2710411-A1 (CA)
Inventor: HOFACKER STEFFEN
IPC: A61Q11/00
Filed: 2008-10-08
Abstract: The invention relates to a process for the preparation of novel aromatized chewing foams for the oral care sector based on polyurethane-polyureas and aromatizing compositions.
Patent CA-2712674-A1 (CA)
Title: Mobile station apparatus, mobile communication system and communication method
Inventor: YAMADA SHOHEI
IPC: H04W24/10
Filed: 2009-04-14
Abstract: In a mobile communication system in which an space of a physical downlink control channel for a mobile station apparatus to search is defined based on a mobile station identity assigned from a base station apparatus, the base station apparatus places a physical downlink control channel including a first mobile station identity or a physical downlink control channel including a second mobile station identity in a search space of a physical downlink control channel corresponding to the first mobile station identity when the base station apparatus assigns a plurality of mobile station identities to the mobile station apparatus, and when a plurality of mobile station identities is assigned from the base station apparatus, the mobile station apparatus performs decoding processing of the physical downlink control channel including the first mobile station identity and the physical downlink control channel including the second mobile station identity in the search space of the physical downlink control channel corresponding to the first mobile station identity.
Patent CA-2713620-A1 (CA)
Title: Revetement de gaine isole contre les rugosites
Inventor: YEUNG KAM YUEN RICKY
IPC: A41D27/00
Filed: 2010-08-25
Abstract: Connecteur de fixation de vêtement disposant d'une couche de ramollissement. Le connecteur inclut : un membre de connexion ayant un premier côté disposant de structures de connexion, et ayant au moins une paire de bords disposés à l'opposé; une couche de couverture isolante à la rugosité molle ayant une zone de support fendue incluant une pluralité de fentes à travers lesquelles les structures de connexion s'étendent, et une zone non fendue. La couche de couverture isolante à la rugosité molle disposant d'une paire de bords disposés à l'opposé joints ensemble afin de former une poche ayant un bord d'extrémité entre la paire de bords disposés à l'opposé, et enveloppant le membre de connexion pour entourer et empocher le membre de connexion tout en permettant aux structures de connexion du membre de connexion de dépasser à travers les fentes de la couche de couverture isolante à la rugosité molle.
Patent CA-2714502-A1 (CA)
Inventor: EVERLAND HANNE
IPC: A61L27/56
Filed: 2009-03-02
Abstract: The present invention provides for a composition, for augmentation and regeneration of living tissue in a subject, comprising a population of porous microparticles of a biodegradable polymer, one or more mammalian cell populations, and optionally, a biocompatible adhesive.
Patent CA-2715251-A1 (CA)
Inventor: BRADSHAW JEFF
IPC: F16F5/00
Filed: 2009-02-05
Abstract: A hydromount assembly includes a first fluid chamber and a second fluid chamber that communicate with one another through an inertia track. The inertia track is interposed between the first and second fluid chambers, and is used as a fluid actuating plunger to move relative to at least one of the first and second chambers in response to vibration to pump fluid from the first chamber to the second chamber, and vice versa, through the inertia track. An opening extends through the first and second fluid chambers and the inertia track and receives a shaft therein. The inertia track is secured to the shaft so that axial movement of the shaft results in axial movement of the inertia track. Elastomeric portions of the hydromount may be differently tuned from one another. The center mount hydromount may be selectively assembled with a body mount, or the body mount integrated into the hydromount whereby the center mount arrangement increases the functionality of the damper.
Patent CA-2716635-A1 (CA)
Inventor: SCODA ENRICO
IPC: G06F17/21
Filed: 2009-02-26
Abstract: A method, computer readable medium and system for web content optimization in single page display environment includes receiving in a system with a single page display environment an engagement of an activator for a data picker for at least one form field in a form page. The form page is replaced with a data picker web page associated with the engaged activator in the single page display environment. A selection for the at least one form field from the data picker web page is received. The data picker web page is replaced with the form page in the single page display environment. The form page is filled with any previous-ly entered data and the at least one form field with the received selection.
Patent CA-2716890-A1 (CA)
Inventor: ADAMZIK MICHAEL
IPC: C07C67/08
Filed: 2010-10-06
Abstract: The present invention relates to a process for preparing polyol esters by reacting polyols with linear or branched aliphatic monocarboxylic acids having 3 to 20 carbon atoms by partial recycling of the aliphatic monocarboxylic acid removed into the esterification reaction or into subsequent esterification batches.
Patent CA-2719239-A1 (CA)
Inventor: KAWASETSU NOZOMU
IPC: F03D1/06
Filed: 2009-08-26
Abstract: A wind-turbine blade that prevents foreign matter from entering the inside thereof during transportation and that can be efficiently assembled in good condition is provided. A  wind-turbine blade (9) includes a skin (14) that forms a long and hollow shape, and a main spar (16) that extends in the longitudinal direction and reinforces the skin (14) from the inside thereof. The main spar (16) is divided into a blade--root-side main spar (31) and a blade-tip-side main spar (33) in the longitudinal direction; the blade-root-side main spar (31) and the blade-tip-side main spar (33) have connection sections (50) that are connected to each other; the skin (14) is divided into a connection-section skin (25), located at a position corresponding to the connection sections (50), a blade-root-side skin (21), and a blade-tip-side skin (23); and openings (43) formed in the blade-root-side skin (21) and the blade-tip-side skin (23) are blocked off by blanking plates (45).
Patent CA-2720393-A1 (CA)
Inventor: HATA SEIJI
IPC: C12P19/14
Filed: 2009-03-31
Abstract: The inventive process converts cellulosic biomass into a gel-like state that is readily hydrolyzed by appropriate enzymes. First the biomass is mechanically reduced in size. The biomass is then mixed and kneaded with an aqueous solution of a hydrophilic polymer that acts as a conditioning agent or as a co-solvent.  During mixing the cellulose (and hemicellulose) in the biomass swells and becomes hydrated forming a viscous gel-like material. The processed material can then be thinned through the addition of water whereupon hydrolytic enzymes are mixed into the material and rapid hydrolysis into free sugars takes place. Dextrins are effective hydrophilic polymers for conditioning biomass. Polyvinyl alcohol is a particularly effective conditioning agent for use with biomass when converted into a viscous gel by adding bo-rate ions.
Patent CA-2721283-A1 (CA)
Inventor: AHLERS MICHAEL
IPC: A23L29/20
Filed: 2009-04-15
Abstract: The present invention relates to a method for manufacturing a rapidly wetting material containing natural hydrocolloid, said material in the shape of a molded body, in which a material in the shape of a molded body containing a natural hy-drocolloid is subjected to a plasma. (57) Zusammenfassung: Die vorliegende Erfindung betrifft ein Verfahren zur Herstellung eines schnell benetzbaren, naturliches Hydrokolloid enthaltenden Materials in Gestalt eines Formkorpers, bei dem ein naturliches Hydrokolloid enthaltendes Material in Gestalt eines Formkorpers einem Plasma ausgesetzt wird.
Patent CA-2722098-A1 (CA)
Title: Dam construction method utilizing freezing technique
Inventor: YANG JU
IPC: E02B7/02
Filed: 2009-04-16
Abstract: A dam construction method utilizing refrigerating technology is provided, the method takes natural water as the material to construct the dam and constructs an ice dam body by utilizing the refrigerating technology. The method includes the following steps:  choosing the forms and quantity of ice unit bodies, determining the positions and quantity of frozen contact: points, manufacturing sufficient ice unit bodies by frozen units, choosing heat insulating material with high performance as the heat preservation layer to cover on the outside of the frozen ice unit bodies; temporarily fixing the ice unit bodies; quickly freezing the seams of the ice unit bodies to form a whole ice dam; mounting temporary generating equipment and completing the temporary dam body; thawing the ice dam body after a permanent dam body is completed.
Patent CA-2724020-A1 (CA)
Inventor: GOLDING BERNARD
IPC: A61P35/00
Filed: 2009-05-13
Abstract: This invention relates to the discovery of substituted analogues of the selective platelet lowering agent anagrelide with reduced potential for cardiovascular side-effects which should lead to improved patient compliance and safety in the treat-ment of myeloproliferative diseases. More specifically, the present invention relates to certain imidazoquinazoline derivatives which have the general formula shown below wherein the substituents have the meanings defined in claim 1: and which have utili-ty as platelet lowering agents in humans. The compounds of the present invention function by inhibiting megakaryocytopoeisis and hence the formation of blood platelets.
Patent CA-2724045-A1 (CA)
Title: Foldable walker apparatus
Inventor: LIU JULIAN
IPC: A61H3/04
Filed: 2008-10-09
Abstract: The present invention relates to, in combination, a foldable walker and a collapsible basket. The walker includes a pair of spaced-apart, operatively interconnected frame members, each having an upper end for placing one's hand and a lower end. The walker has ground-engaging wheels rotatably mounted to the lower end of the frame members.  The walker has means for bringing together the frame members for folding the walker.  The collapsible basket includes a pair of spaced-apart end members. Each end member has a rigid peripheral portion and is connectable with a respective one of the frame members. The collapsible basket includes a basket member. The basket member is made of flexible fabric. The basket member extends between and is supported by the rigid peripheral portions of the end members. The end members are moveable towards each other, the basket member thereby folding to collapse the basket when folding the walker.
Patent CA-2724404-A1 (CA)
Inventor: JABLONSKI JASON DIRK
IPC: G05D16/16
Filed: 2009-04-21
Abstract: Apparatus to regulate fluid flow are disclosed. The apparatus includes an example regulator valve and an example automatically-adjusting or self- adjusting amplifier valve to maintain fluid flow during low downstream demand fluid flow conditions, and to maintain the operational accuracy and stability of the regulator valve during higher downstream demand fluid flow conditions.
Patent CA-2725069-A1 (CA)
Inventor: COUSINEAU ROBERT
IPC: E21D20/00
Filed: 2010-12-10
Abstract: A seismic tool assembly for effecting a drill hole and enlarging a lowermost end thereof whereby an anchor can be set more securely therein. A drill bit is inserted through an opening in a drill stop member, which is mounted on a stabilizer surrounding the hole. The bit is then inserted through each of the drill stop member and the stabilizer to attain a drilling position. The lower end of the bit has a cutting portion having a cutting radius greater than that of the bit body whereby, when the bit is inserted fully into a lowermost end of the hole and rotated, the cutting portion enlarges the lowermost end, whereby flanged portions of an anchor will rest within the enlarged area, retaining the anchor in place. A cap portion and an upper end of the stabilizer are threaded for permitting threaded engagement of the cap portion to the threaded upper portion of the stabilizer so as to prevent disengagement of the drill stop member from the stabilizer during a drilling process.
Patent CA-2730302-A1 (CA)
Title: Utilisation de derives d'indole comme activateurs de nurr-1, pour le traitement de la maladie de parkinson
Inventor: BOUBIA BENAISSA
IPC: A61P25/16
Filed: 2009-07-09
Abstract: La présente invention concerne un composé dérivé de l'indole, notamment utile en thérapeutique, caractérisé en ce qu'il est choisi parmi iii) les composés de formule (I) dans laquelle : R1 représente un halogène ou un groupe trifluorométhyle, R2 représente un atome d'hydrogène ou un groupe alkyle en C1-C4, R3 représente un groupe isopropyle (1-méthyléthyl) ou un groupe tertio-butyle (1,1-diméthyléthyl), n = 3 ou 4 les sels pharmaceutiquement acceptables desdits composés de formule (I). Application : Traitement des maladies neurodégénératives et en particulier de la maladie de Parkinson.
Patent CA-2733283-A1 (CA)
Title: Clostridial neurotoxins with altered persistency
Inventor: FREVERT JUERGEN
IPC: C07K14/33
Filed: 2009-08-28
Abstract: The invention relates to a polypeptide comprising: (a) a HC-domain or fragment thereof of the neurotoxic component of a clostridial toxin; and (b) a first LC domain or fragment thereof of the neurotoxic component of a clostridial toxin; and (c) at least one further LC domain or fragment thereof of the neurotoxic component of a clostridial toxin wherein the first and the at least one further LC domain may be the same or different from each other, and wherein each of said fragments of said first and of said at least one further LC domain still exhibits proteolytic activity.
Patent CA-2735101-A1 (CA)
Inventor: MARQUILLAS OLONDRIZ FRANCISCO
IPC: C07C213/10
Filed: 2009-10-09
Abstract: The present invention describes a novel process for the preparation of optically active (S)-(-)-2-(N-propylamino)-5-methoxytetraline and (S)-(-)-2-(N-propylamino)-5-hydroxytetraline compounds based on the optical resolution of mixtures of the enantiomers of 2-(N-propylamino)-5-methoxytetraline and 2-(N-propylamino)-5-hydroxytetraline respectively.  This process comprises (a) reacting a mixture of the enantiomers of said compounds with an optically active organic acid to form diastereoisomeric salts and separating the salts by crystallization. Said compounds are useful in the preparation of (6S)-(-)-5,6,7,8-tetrahydro-6-[propyl-(2-thienyl)ethyl]amino-1-naphthol (Rotigotine).  Rotigotine is a dopamine agonist and is indicated for the treatment of Parkinson's disease.
Patent CA-2736591-A1 (CA)
Title: Procede de recherche d'au moins un analyte dans un milieu susceptible de le contenir
Inventor: CAU JEAN-CHRISTOPHE
IPC: G01N21/47
Filed: 2009-09-10
Abstract: L'invention concerne un procédé pour rechercher la présence d'un analyte lié à une sonde, dans lequel un motif géométrique périodique (24), constituant un système diffractant (2), est formé par une alternance de zones comportant une sonde A, et de zones ne comportant pas la sonde A. Le système diffractant (2) est réalisé pour être diffractant avant une étape de sensibilisation, c'est-à-dire une étape au cours de laquelle une sonde est mise en contact temporairement avec un milieu susceptible de contenir un analyte et au cours de laquelle l'éventuel analyte se fixe à la sonde. Le procédé comporte au moins les étapes de : - mesure d'une puissance P1 d'un faisceau de diffraction d'ordre 1 d'un champ de diffraction produit par le système diffractant, sonde non sensibilisée, - sensibilisation de la sonde A, - mesure d'une puissance P1a d'un faisceau de diffraction d'ordre 1 d'un champ de diffraction produit par le système diffractant, - comparaison des puissances mesurées P1 et P1a.
Patent CA-2736638-A1 (CA)
Inventor: VEREGIN RICHARD P N
IPC: G03G13/01
Filed: 2011-04-06
Abstract: The present disclosure provides processes for producing images with toner particles. In embodiments, toner particles of a certain diameter in size are applied to a substrate as an incomplete monolayer, and then fused to form an image that is a complete monolayer and possesses a thickness less than the diameter of the particles utilized to form the image.
Patent CA-2738438-A1 (CA)
Inventor: BIRAU MARIA
IPC: C09K11/07
Filed: 2011-04-27
Abstract: A fluorescent solid ink, and a method for making such ink, including an ink vehicle and a fluorescent particle. The fluorescent particle includes a fluorescent pigment, such as a trans-dicarboxylic-indenofluorenone, and at least one stabilizing wax chemically attached to the fluorescent pigment. The stabilizing wax includes an amine group at its terminal end and the fluorescent pigment includes at least one carboxylic acid group, where the amine group reacts with the carboxylic acid group to form an amide bond.
Patent CA-2739660-A1 (CA)
Inventor: SMETANNIKOV ANDREI FILIPPOVICH
IPC: C22B11/00
Filed: 2009-09-08
Abstract: The invention relates to methods for producing a bulk enrichment concentrate for extracting noble metals from clay-salt waste (slurries) from plants which process potassium-magnesium ores and rock salt. The method for producing a bulk concentrate for extracting noble metals involves the three-stage hydrocyclone separation of the slurries and the isolation of the concentrate. The bulk concentrate produced by the hydrocyclone separation in the form of a mixture of sedimentary and floating material with a 1:1 solid-to-liquid ratio is desiccated, pre-dried, granulated and then dried.
Patent CA-2741129-A1 (CA)
Inventor: STEMP MICHAEL
IPC: C25B1/02
Filed: 2009-10-23
Abstract: A system for distributing electric power from a wind farm generating medium to high voltage AC electricity to multiple electrolyser modules for producing hydrogen. A system for distributing electric power from a wind farm generating medi-um voltage DC electricity to multiple electrolyser modules for producing hydrogen.
Patent CA-2744567-A1 (CA)
Inventor: BEASLEY PATRICK DAVID LAWRENCE
IPC: G01S7/292
Filed: 2009-11-19
Abstract: A DDS based system, such as a radar, includes means for generating a plurality of transmission signals using a DDS, and means for integrating signals derived therefrom, such as received signals. The system further includes means for varying the relative starting phase of the plurality of transmission signals, or adjusting the DDS input clock whilst maintaining similar primary output frequency characteristics of the transmission signals. The approach has the effect of changing the location of unwanted frequency spurs in each of the transmission signals, and hence the effects of these are decreased in the integration process. An improvement in the sensitivity of the system results. Although primarily suited to radar applications the invention may find utility in other systems such as sonar or lidar systems.
Patent CA-2745283-A1 (CA)
Inventor: VORONOV ALEX
IPC: H01J61/20
Filed: 2011-07-06
Abstract: Known mercury-vapor discharge lamps for planar irradiation are provided with a lamp bulb made of quartz glass, which encloses a closed discharge space having a non-linear gas-discharge channel. In order to provide a structurally simple lamp, which also guarantees a highest possible homogeneity of the UV irradiation even for a small distance to the surface to be treated, it is proposed according to the invention that the lamp bulb is formed as a quartz-glass chamber defined by straight walls and having bottom, top, and side walls and is divided into sub-chambers by several separating webs made of quartz glass and projecting from the bottom wall to the top wall, wherein these sub-chambers include a front-most sub-chamber and a rear-most sub-chamber and form in series interconnection the non-linear gas-discharge channel, wherein the separating webs extend alternately from one side wall up to close to the opposite side wall, while leaving open a gap connecting adjacent sub-chambers in a fluid-communicating manner, wherein one electrode is allocated to the front-most sub-chamber and the other electrode is allocated to the rear-most sub-chamber.