baber/WOPTO huggingface dataset:
Patent AU-2019386792-A1 (AU)
Title: Histone acetylase p300 inhibitor and use thereof
Inventor: FAN LEI
IPC: C07D277/60
Filed: 2019-11-27
Abstract: Provided are a histone acetylase p300 inhibitor and a use thereof, belonging to the field of medicinal chemistry technology. A compound represented by formula (I), or a stereochemical isomer thereof, or a solvate thereof, or a pharmaceutically acceptable salt thereof, can inhibit the activity of histone acetylase p300 and inhibit the proliferation activity of a variety of tumor cells. <img file="577633dest_path_image001.jpg" he="80.79" img-content="drawing" img-format="jpg" inline="yes" orientation="portrait" wi="88.19"/>
Patent AU-2019391397-A1 (AU)
Title: Vitamin D micro-emulsions and uses thereof
Inventor: EZRA RAFAEL
IPC: C07F9/10
Filed: 2019-12-06
Abstract: Pharmaceutical compositions designed to deliver Vitamin D efficiently to the eyes and methods for using same are described herein. More particularly, ophthalmic pharmaceutical compositions for use in protecting eyes from the harmful effects of light exposure, in maintaining a healthy ocular state, and in treating disorders of the eye are described herein. The composition may also be used as a medical device which, once on the surface of the eye, creates a layer that filters electro-magnetic radiation in different wave lengths. The composition may also be used as a medical device which eases the symptoms and signs of eye-surface conditions.
Patent AU-2019391601-A1 (AU)
Title: A heliostat sub-assembly
Inventor: DREWES KURT FRIEDRICH
IPC: F24S25/63
Filed: 2019-12-04
Abstract: The invention relates to a heliostat sub-assembly and to a method of forming such a sub-assembly. The method of mounting a concave mirror to a supporting structure of a heliostat includes the steps of bonding a plurality of risers at predetermined spaced intervals to a rear face of the mirror, each riser having a bonding pad and a stem extending from the bonding pad, and applying a predetermined concave curvature to the mirror by conforming the front face of the mirror with a convex forming jig or die. The supporting structure and curved mirror are then aligned, and the supporting structure is clinched to the stems of the risers when the curved mirror is conformed with the forming die. The riser stems may be coupled to the bonding pads via multi-axial joint assemblies to enable limited multi-pivotal movement of the stems relative to the bonding pads to facilitate alignment of faces of the stems with the faces of the ribs defined by webs, and relative expansion and contraction of the mirror and supporting structure, the overlap between the riser stems and the webs being sufficient to accommodate clinching with variations in curvature of the glass sheet.
Patent AU-2019399499-A1 (AU)
Title: Floor mats and methods of producing the same
Inventor: TRIMBLE CRAIG
IPC: B32B3/02
Filed: 2019-11-12
Abstract: Various implementations include a mat having a lower surface and first and second edge portions that define at least a portion of a perimeter of the mat. The mat also includes a plurality of ribs that extend away from the lower surface of the mat for contacting the floor. Each rib has a longitudinal axis that extends between ends of the rib, and at least a portion of the plurality of ribs includes one or more branches that extend transversely to the longitudinal axis and are axially spaced apart from each other. The ribs are spaced apart from each other over the lower surface such that adjacent ribs define a valley therebetween. Water and/or debris can flow through the valleys. In addition, the longitudinal axis of each rib intersects the first and second edge portions of the mat at angles that are greater than 0˚ and less than 90˚.
Patent AU-2019444480-A1 (AU)
Title: Determining and identifying anomalies in fork meters
Inventor: SMITH KEVIN F
IPC: G01N9/00
Filed: 2019-05-09
Abstract: A method for determining a process anomaly in a fluid flow system, the system having a meter with immersed elements immersed in a fluid of a fluid flow is disclosed. The method includes determining, using a data processing circuit (132), a measured density of the fluid in the fluid flow system, determining, using the data processing circuit (132), whether the fluid flow system is experiencing a density anomaly based on a relationship between the measured density and an expected density of the fluid in the fluid flow system, determining, using the data processing circuit (132), a measured phase difference of vibrations of the immersed elements of the meter, determining, using the data processing circuit (132), whether the fluid flow system is experiencing a phase anomaly based on a relationship between the measured phase difference and a target phase difference of the vibrations of the immersed elements in the fluid flow, and identifying an anomaly of the fluid flow system based on the determination of whether there is a density anomaly and the determination of whether there is a phase anomaly.
Patent AU-2019448769-A1 (AU)
Title: Sensor units for use with fire suppression systems
Inventor: PRAT JORDI ABAD
IPC: A62C35/13
Filed: 2019-05-31
Abstract: A sensor unit for a fire suppression system includes a sensor module, a display module, a controller, and an antenna. The sensor module includes a first housing including a fitting configured to be coupled to a tank containing a fluid, a pressure sensor located within the first housing and configured to sense a pressure of a fluid and provide pressure data related to the pressure of the fluid, and a temperature sensor located within the first housing and configured to sense a temperature and provide temperature data related to the temperature of the fluid. The display module includes a second housing selectively attached to the first housing such that the display module is selectively removable from the display module, and a user interface. The controller is operatively coupled to the pressure and temperature sensors. The antenna is configured to transfer the pressure data and the temperature data to a network.
Patent AU-2020202838-A1 (AU)
Title: Vista regulatory T cell mediator protein, vista binding agents and use thereof
Inventor: NOELLE RANDOLPH J
IPC: A61P19/02
Filed: 2020-04-29
Abstract: The present invention relates to a novel regulatory T cell protein. This protein, designated PD-L3 OR VISTA resembles members of the PD-L1 family, identified a novel and structurally-distinct, Ig-superfamily inhibitory ligand, whose extra-cellular domain bears homology to the B7 family ligand PD-Ll. This molecule is designated as PD-L3 OR VISTA or V-domain Immunoglobulin Suppressor of T cell Activation (VISTA). Expression of VISTA is primarily within the hematopoietic compartment and is highly regulated on myeloid APCs and T cells. Therapeutic intervention of the VISTA inhibitory pathway represents a novel approach to modulate T cell-mediated immunity for the treatment of a wide variety of cancers, e.g., ovarian, bladder cancer and melanomas. Also, VISTA proteins, especially multimeric VISTA proteins and antibodies may be used to suppress T cell immunity in autoimmune disease, allergy, infection and inflammatory conditions, e.g. multiple sclerosis and arthritic conditions such as RA. FULL LENGTH SEQUENCE OF MURINE PD-XL MGVPAVPEASSPRWGTLLLAIFLAASRGLVAAFKVTTPYSLYVCPEGQNA 50 TLTCRILGPVSKGHDVTIYKTWYLSSRGEVQMCKEHRPIRNFTLQHLQHH 100 GSHLKANASHDQPQKHGLELASDHHGNFSITLRNVTPRDSGLYCCLVIEL 150 KNHHPEQRFYGSMELQVQAGKGSGSTCMASNEQDSDSITAAALATGACIV 200 GILCLPLILLLVYKQRQVASHRRAQELVRMDSSNTQGIENPGFETTPPFQ 250 GMPEAKTRPPLSYVAQRQPSESGRYLLSDPSTPLSPPGPGDVFFPSLDPV 300 PDSPNSEAI* ALIGNMENT OF EXTRACELLULAR DOMAINS OF MURINE PD-XL WITH B7-H1 (PD-Li), B7-DC (PD-L2), B7-H3, AND B71. PD-XL ---- F ITPYSLY C-- PEGGS LGPVSKGHDVTIYKTWYLSSRGEVQM B7-H1(PD-L) ---- APKDL ----- EY'S --PVERELDLLALVVYWEKE-DEQ- B7-DC_(PD-L2) L--- APKEVY ------DVSV t ------------------------- DRRE B7-H3_(CD276) ---- VSEDP a---LV1iDA F S--SPEPGFSLAQLNLIWQLT-DTKQL B7-H4(B751) LII GKHFI TFTSAGNI ---- EPDIKLNGIVIQWLKE-GIKGL PD-XL C RPIRN-FTSLQHHGSHL ASH QPQKHGLELASDHH S P B7-H1_(PD-Li) VIFVA GEEDLK SNFRG--- PK K--------- B7-DC (PD-L2)CT EGIRASLQKVENDTSLQSE PL---------- l 8 B7-H3(CD276) VitFTEGRD---- SAYSN--- f VQ--------- S B7-H4(B751) VH FKEGKDDLS & EMFAG--- V B7H_(B7Si ki n PD-XL ---------- HHPEQRF--------------YGSME 0VO KG---- B7-H1_(PD-LI) V IlSYGGA-M PYRKINQRSVDPA---TSEHEL- -EGYEA B-C(PD-L2) ,I YSYMRIDTRILEVPG ----- TGEVQI -RZi B7-DC_(PD-L2) I AW1YKYV_ B7-H3_(CD276) IQDF-Yt A PYSK--PS LEPNKDLRPGMVT _(B781) TSKG SM---P -NDYN-----ASSES R PD-XL ------------ ST--------------- S EQDSDSIT B7-Hi_(PD-L) VI. N--SDHQP 1GKRSVTTSRTEGMLLNVTSS VNAT SQPGQNHT B7-DC (PD-L2) VQN------- PANTSHIRTPEGLYQS KPQPRS MKELTS ~7D_(PDL) "INSMERGV HS QNV iI B7-H3_(CD276) EgKD--GQGVP NVTQMANERGLFDV VVLGANG QQDA 7-4_(B71) ASQVDQGANF VS .ELNSENVTMKVVMYNVTIEi IAK--ATG PD-XL A------------------- B7-H1_(PD-Li) ELIIPELPATHPPQNRTH-- B7-DC_(PD-L2) IIDPLSRMEPKVPRTW---- B7-H3_(CD276) SVTITGQPLTFPPEA----- B7-H4_(B7S1) DIKVTDSEVKRRSQLQLLNSG
Patent AU-2020203728-A1 (AU)
Title: Survival platform
Inventor: WESCOTT BRETT
IPC: B63B7/08
Filed: 2020-06-05
Abstract: A survival platform, comprising two flexible outer sheets (4, 5), the outer sheets each having a circumference (2) and being sealed together at their circumferences (2) to 5 define a void (18) therebetween, the survival platform further comprising an inner flexible sheet (6) interposed between the outer sheets (4, 5) and dividing the void (18) into two sub-voids (18a, 18b), and means (8) for inflating the survival platform by introducing a gas into the void to increase a gas pressure therewithin, in which the inner sheet (6) is arranged such that, should one of the outer sheets (4, 5) be breached 10 at a breach, the gas pressure within the void will tend to force the inner sheet (6) through the breach, thereby to block the breach and reduce the level to which gas escapes through the breach.
Patent AU-2020242921-A1 (AU)
Title: Supraparticle formulations
Inventor: WISE ANDREW
IPC: A61K9/16
Filed: 2020-03-19
Abstract: The present disclosure relates to supraparticles loaded with high levels of payload and having controlled payload release profiles. In particular, supraparticles made of mesoporous silica nanoparticles and elecrosprayed with alginic acid which is then coated or formulated with biodegradable materials is disclosed. Such supraparticles may be used in a range of therapeutic applications.
Patent AU-2020248987-A1 (AU)
Title: Magnetic assemblies and processes for producing optical effect layers comprising oriented non-spherical magnetic or magnetizable pigment particles
Inventor: LOGINOV EVGENY
IPC: B42D25/41
Filed: 2020-02-17
Abstract: The present invention relates to the field of magnetic assemblies and processes for producing optical effect layers (OELs) comprising magnetically oriented non-spherical magnetic or magnetizable pigment particles on a substrate. In particular, the present invention relates to magnetic assemblies processes for producing said OELs as anti-counterfeit means on security documents or security articles or for decorative purposes.
Patent AU-2020250626-A1 (AU)
Title: Redox enzymes in animal feed compositions
Inventor: LI MING
IPC: C12N9/00
Filed: 2020-04-05
Abstract: Novel superoxide dismutases of fungal origin are active, gastric stable and thermal stable, and effective for use in animal feed additives. The use of superoxide dismutase in animal feed improve animal growth, animal health and intestinal health of animals.
Patent AU-2020252421-A1 (AU)
Title: Marker for objects that indicates the degree of release into the environment of elements that are difficult or slow to biodegrade (harmful elements)
Inventor: COSTA BOTEY JOSÉ MARÍA
IPC: A41D27/00
Filed: 2020-03-30
Abstract: The invention relates to a marker for objects that indicates the degree of release into the environment of elements that are difficult or slow to biodegrade (harmful elements), which consists of an element (1, 1', 1'') having a structure that ostensibly modifies its appearance at a rate in accordance with the wear of the fabric of a garment (2) for which it is intended, alerting the user. The element is a button (1) or a tag (1') comprising two different looking layers, a superficial layer (11) and a central or bottom layer (12), the external layer (11) being "wearable" and disappearing at a rate in accordance with the fabric of the garment (2). In another embodiment, the element is stitching (1'') consisting of a "wearable" thread that disappears at a rate in accordance with the deterioration of the fabric of the garment (2) for which it is intended.
Patent AU-2020260513-A1 (AU)
Title: Targeted ad redistribution
Inventor: BRENNER VADIM
IPC: G06Q30/02
Filed: 2020-10-29
Abstract: OF THE DISCLOSURE 
A user may view a video. The user may share a portion or the entirety of the 
video. The user may provide tags or comments with the shared video. The tags 
or comments may indicate a mood associated with the shared video. The server 
5 receiving the request to share the video may have metadata associated with the 
video. Additional metadata may be stored associated with smaller portions of 
the video. As an example, metadata may indicate the mood of a scene. The 
server may embed one or more advertisements into the shared video. The one or 
more advertisements may be targeted. Selection of advertisements may be based 
10 on a match between advertisement metadata and a user profile of the sharing 
user, a user profile of the receiving user, tags or comments provided by the 
sharing user, and metadata for the video or the clip.
4/9 
400 
160 
You are Select Clip 440 
410--- watching: 
American 
Idol on FOX Clip 1 Description - 445 
415--- Choose 
Friend 
420----- Friend1 C Clip 2 Description 
----- 450 
425--- Friend2 
Clip 3 Description 455 
430--- Friend3 
435 #LOL 460 
FIG. 4
Patent AU-2020276793-A1 (AU)
Title: Small molecules for treating cancer, inhibiting chemokine activity and/or inducing cell death
Inventor: PELED AMNON
IPC: C07D215/36
Filed: 2020-05-15
Abstract: Compounds capable of, or usable in, inducing death of cancer cells and/or modulating a biological activity of a chemokine e.g., cell migration, and/or treating diseases and disorders associated with a biological activity of a chemokine and/or cell migration, and/or in treating cancer, are provided herein. The compounds are collectively represented by Formulae (la) or (lb); wherein A, B, D, E, G and R1-R5 are as defined in the specification, with one or more of D, E and G, preferably E, is hydroxy.
Patent AU-2020277162-A1 (AU)
Title: Selective modification of polymer subunits to improve nanopore-based analysis
Inventor: GUNDLACH JENS H
IPC: C07H21/02
Filed: 2020-11-25
Abstract: The present disclosure provides method and systems for improving 
nanopore-based analyses of polymers. The disclosure provides methods for selectively 
modifying one or more monomeric subunit(s) of a kind a pre-analyte polymer that results 
5 polymer analyte with a modified subunit. The polymer analyte produces a detectable 
signal in a nanopore-based system. The detectable signal, and/or its deviation from a 
reference signal, indicates the location of the modified subunit in the polymer analyte 
and, thus, permits the identification of the subunit at that location in the original pre
analyte polymer.  
10
Patent AU-2020307390-A1 (AU)
Title: Reduced dose metaxalone formulations
Inventor: GANDE MUKTEESHWAR
IPC: A61K9/20
Filed: 2020-06-23
Abstract: Oral dosage forms of metaxalone having improved bioavailability in the fed and fasted states, including dosage forms that employ a reduced dose based on such improved bioavailability.
Patent AU-2020314494-A1 (AU)
Title: Stable AST-3424 injection preparation and preparation method
Inventor: DUAN JIANXIN
IPC: A61K47/10
Filed: 2020-07-14
Abstract: A stable AST-3424 injection preparation, being a solution containing 0.1-200 mg/ml or 1-200 mg/ml of AST-3424 active ingredients. A solvent in the solution contains a C2-C8 monohydric alcohol. The preparation method comprises the following steps: performing first dissolution preparation on the AST-3424 active ingredients and a partial prescription amount of ethanol; adding a prescription amount of propylene glycol for the second-time dissolution preparation; and then, adding the remaining prescription amount of ethanol for mixing and dissolving to obtain a solution containing 1-200 mg/ml of AST-3424 active ingredients. The solvent of the AST-3424 injection is water, or a glucose solution, ethanol, and a propylene glycol solute consist of the AST-3424 active ingredients, an isotonic regulator, and a pH regulator. The concentration of the AST-3424 active ingredients of the injection is 0.001-1.000 mg/ml, the pH of the injection is 6.8-10.5, and the solution is an isotonic solution.
Patent AU-2020315413-A1 (AU)
Title: Composition and method of treating bacterial and viral pathogens in plants
Inventor: EVELAND WINSOR GEBHARD
IPC: A01P1/00
Filed: 2020-07-16
Abstract: Antimicrobial compositions comprising gum rosin, pine oil, and salt water mitigate or eliminate detrimental plant microorganisms, and mitigate or reverse plant diseases such as Gram-negative bacterial diseases. The compositions are effective against Gram-negative bacterial diseases (including citrus greening disease or HLB caused by
Patent AU-2020328023-A1 (AU)
Title: Systems and methods for privacy-enabled biometric processing
Inventor: STREIT SCOTT EDWARD
IPC: G06K9/62
Filed: 2020-08-13
Abstract: In one embodiment, a set of feature vectors can be derived from any biometric data, and then using a deep neural network ("DNN") on those one-way homomorphic encryptions (i.e., each biometrics' feature vector) an authentication system can determine matches or execute searches on encrypted data. Each biometrics' feature vector can then be stored and/or used in conjunction with respective classifications, for use in subsequent comparisons without fear of compromising the original biometric data. In various embodiments, the original biometric data is discarded responsive to generating the encrypted values. In another embodiment, the homomorphic encryption enables computations and comparisons on cypher text without decryption of the encrypted feature vectors. Security of such privacy enable biometrics can be increased by implementing an assurance factor (e.g., liveness) to establish a submitted biometric has not been spoofed or faked.
Patent AU-2020328025-A1 (AU)
Title: Imidazolyl pyrimidinylamine compounds as CDK2 inhibitors
Inventor: YE MIN
IPC: C07D403/14
Filed: 2020-08-13
Abstract: The present application provides imidazolyl pyrimidinylamine inhibitors of cyclin-dependent kinase 2 (CDK2), as well as pharmaceutical compositions thereof, and methods of treating cancer using the same.
Patent AU-2020388636-A1 (AU)
Title: Substituted heterocyclics with therapeutic activity in HIV
Inventor: DEBNATH ASIM KUMAR
IPC: A61K31/437
Filed: 2020-11-19
Abstract: Substituted heterocyclic substituted pyrrole carboxamide compounds such as those represented by Formula I or Formula II are provided herein. Such compounds, or pharmaceutically acceptable salts thereof, can be used in the treatment of HIV infection and related conditions.
Patent AU-2020420252-A1 (AU)
Title: Control device and work machine
Inventor: MATSUI YUKI
IPC: G05D1/02
Filed: 2020-01-09
Abstract: A control device, for executing travel control of a self-propelled work machine, wherein are provided a rotation means that rotates the work machine so that the work machine travels on the inner side of a boundary of a work area, an evaluation means that evaluates the complexity of the shape of the boundary in the work area, and a changing means that changes the rotational state of the work machine before the work machine is rotated on the basis of evaluation results from the evaluation means.
Patent AU-2021200464-A1 (AU)
Title: Superconducting bi-directional current driver
Inventor: NAAMAN OFER
IPC: H03K3/38
Filed: 2021-01-25
Abstract: SUPERCONDUCTING BI-DIRECTIONAL CURRENT DRIVER 
ABSTRACT 
One example includes a superconducting bidirectional current driver. The current driver 
includes a first direction superconducting latch that is activated in response to a first activation 
signal and a second direction superconducting latch that is activated in response to a second 
activation signal. The second direction superconducting latch is activated to provide a first 
current path of an input current through the first direction superconducting latch and through a 
bidirectional current load in a first direction. The first direction superconducting latch is 
activated to provide a second current path of the input current through the second direction 
superconducting latch and through the bidirectional current load in a second direction opposite 
the first direction.
Patent AU-2021201668-A1 (AU)
Title: Botulinum neurotoxins with modified light chain specifity and methods for producing same
Inventor: DUNNING FRANCIS MARK
IPC: C07K14/705
Filed: 2021-03-17
Abstract: A protease directed to a non-neuronal SNARE protein is described. The protease is produced by 
selective mutation of a botulinum neurotoxin light chain, and is characterized utilizing a reporting 
construct that includes all or part of the non-neuronal SNARE protein. Such a protease has utility in the 
treatment of diseases associated with hypersecretion, where the hypersecretion is mediated by a non
neuronal SNARE protein. See Fig. 3.
Patent AU-2021209338-A1 (AU)
Title: Scalable modular cooling unit having voltage isolation
Inventor: INAM HAROON
IPC: H02J3/36
Filed: 2021-07-30
Abstract: A modular liquid-cooling block (LCB) is disclosed for cooling high-current switching 
devices deployed in power flow control systems (10). Liquid coolant maybe jetted directly 
onto a cooling plate of an IGBT switching module (direct impingement) or it may impinge 
indirectly onto a wall of the LCB that is thermally coupled to a cooling plate (indirect 
impingement). Indirect impingement may comprise jets of coolant impinging on the 
cooling plate, or a parallel flow of coolant past the cooling plate. Voltage isolation of 
switching modules is provided within each LCB and between LCBs, enabling many 
different series and parallel switching topologies.  
Figure 1 
10
3/7 
30 
24 
22 
31 
33a 33b 
32 
21 
FIG. 3
Patent AU-2021209746-A1 (AU)
Title: Anti-ANGPTL3 antibody and use thereof
Inventor: FU YAYUAN
IPC: C07K16/22
Filed: 2021-01-22
Abstract: The present invention relates to an anti-ANGPTL3 antibody and a use thereof. In particular, the present invention relates to the anti-ANGPTL3 antibody and an antigen binding fragment thereof, or a pharmaceutically acceptable salt or solvent thereof, and a use thereof as a medicine, in particular a use in the preparation of a medicine for treating hyperlipidemia.