baber/WOPTO huggingface dataset:
Patent NZ-542336-A (NZ)
Title: Quinoline and quinoxaline compounds as PDGF-R and/or Lck tyrosine kinase inhibitors
Inventor: SPADA ALFRED P
IPC: A61F2/06
Filed: 1999-11-23
Abstract: Disclosed is a use of a compound in the preparation of a medicament for treating a pathology linked to a hyperproliferative disorder in a patient in need thereof, wherein said pathology is restenosis, and wherein said medicament is formulated as a coating on a stent device, and wherein said compound is of formula I, where: X is L,OH or L2Z2; L1 is (CR3aR3b)r or (CR3aR3b)m-Z3-(CR3aR3'b)n; L2 is (CR3aR3b)p-Z4-(CR3'aR3'b)q or ethenyl; Z1 is CH or N ; Z2 is optionally substituted hydroxycycloalkyl, optionally substituted hydroxycycloalkenyl, optionally substituted hydroxyheterocyclyl or optionally substituted hydroxyheterocyclenyl; Z3 is O,NR4, S, SO or SO2; Z4 is O, NR4, S, SO, SO, or a bond; m is 0 or 1; n is 2 or 3, and n + m = 2 or 3; p and q are independently 0,1,2,3 or 4, and p + q = 0,1,2,3 or 4 when Z4 is a bond, and p + q = 0,1,2 or 3 when Z4 is other than a bond; r is 2, 3 or 4; R1a and R1b are independently optionally substituted alkyl, optionally substituted aryl, optionally substituted heteroaryl, hydroxy, acyloxy, optionally substituted alkoxy, optionally substituted cvcloalkyloxy, optionally substituted heterocyclyloxy, optionally substituted heterocyclylcarbonyloxy, optionally substituted aryloxy, optionally substituted heteroaryloxy, cyano, R5R6N or acylR5N, or one of R1a and R1b is hydrogen or halo and the other is optionally substituted alkyl, optionally substituted aryl, optionally substituted heteroaryl, hydroxy, acyloxy, optionally substituted alkoxy, optionally substituted cycloalkyloxy, optionally substituted heterocyclyloxy, optionally substituted heterocyclylcarbonyloxy, optionally substituted aryloxy, optionally substituted heteroaryloxy, cyano, R5R6N or acylR5N. R1c is hydrogen, optionally substituted alkyl, optionally substituted aryl, optionally substituted heteroaryl, hydroxy, acyloxy, optionally substituted alkoxy, optionally substituted cycloalkyloxy, optionally substituted heterocyclyloxy, optionally substituted heterocyclylcarbonyloxy, optionally substituted substitutedheteroaryloxy,halo, cyano, R5R6N or acylR5N;optionally R3a R3b, R3'a and R3'b are independently hydrogen or alkyl; R4 is hydrogen, alkyl or acyl; and R5 and R6, are independently hydrogen or alkyl, or R5 and R6 taken together with the nitrogen atom to which R5 and R6 are attached form azaheterocyclyl.
Patent NZ-545159-A (NZ)
Title: Method of treating viral infections
Inventor: SMITH HOWARD J
IPC: A61P31/12
Filed: 2004-08-03
Abstract: Provided is the use of interferon, and ribavirin at a dose of less than 400mg/day, in the preparation of a medicament for treatment of viral infection in a patient by co-administration of interferon and ribavirin to the patient wherein said ribavirin is in a slow-release formulation to provide a clinically effective blood level of ribavirin in the portal vein and less than required to provide a clinically effective blood level in the peripheral circulation to thereby provide a dose delivery rate having a selective antiviral and interferon potentiating effect in the liver. Further provided are similar uses with specified dose ranges and viral diseases and corresponding kits with specified unit doses.
Patent NZ-547462-A (NZ)
Title: Heterocyclic aspartyl protease inhibitors
Inventor: ZHU ZHAONING
IPC: C07D405/10
Filed: 2004-12-13
Abstract: Disclosed are compounds of the formula (I) or a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof. These heterocyclic compounds are suitable for inhibiting aspartyl protease, and are particularly used for the treating cardiovascular diseases, cognitive and neurodegenerative diseases, and the methods of inhibiting of Human Immunodeficiency Virus, plasmepins, cathepsin D and protozoal enzymes. Also disclosed are methods of treating cognitive or neurodegenerative diseases using the compounds of formula (I) in combination with a cholinesterase inhibitor or a muscarinic antagonist.
Patent NZ-548107-A (NZ)
Title: A respiratory syncytial virus with a genomic deficiency complemented in trans
Inventor: LUYTJES WILLEM
IPC: A61K38/00
Filed: 2004-12-24
Abstract: Disclosed is a virion of a pneumovirus comprising a viral genome that has a mutation in a gene coding for a G attachment protein or a fusion protein F or a mutation in both genes, said proteins being essential for infectivity of the pneumovirus, whereby the mutation causes a virus produced from only the viral genome to lack infectivity, and whereby the virion comprises the protein in a form and in an amount that is required for infectivity of the virion.
Patent NZ-552659-A (NZ)
Title: Fungicidal compositions for controlling phytopathogenic diseases on crop plants
Inventor: WALTER HARALD
IPC: A01N43/56
Filed: 2005-08-11
Abstract: Disclosed is a method of controlling phytopathogenic diseases on useful plants or on propagation material thereof, which comprises applying to the useful plants, the locus thereof or propagation material thereof a combination of components A and B in a synergistically effective amount, wherein component A is a compound of formula (I), wherein R1 is trifluoromethyl or difluoromethyl and R2 is hydrogen or methyl; or a tautomer of such a compound; and component B is a compound selected from the group consisting of Azoxystrobin, Fludioxonil, Difenoconazole, Cyproconazole or Thiabendazole.
Patent NZ-554493-A (NZ)
Title: Aryl sulfonamide peri-substituted bicyclics for occlusive artery disease
Inventor: SINGH JASBIR
IPC: C07D209/08
Filed: 2005-10-11
Abstract: Disclosed are aryl sulphonamide peri-substituted bicyclics of the formula shown wherein A and B represent a pair of fused 5-, 6- or 7-membered rings, said fused A/B ring system containing from zero to four heteroatoms chosen from nitrogen, oxygen and sulfur and said rings additionally substituted with from zero to four substituents chosen independently from halogen, -OH, loweralkyl, -O-loweralkyl, fluoroloweralkyl, -O-lowerfluoroalkyl, methylenedioxy, ethylenedioxy, alkoxy-Ioweralkyl, hydroxyloweralkyl, oxo, oxide, -CN, nitro, -S-loweralkyl, amino, loweralkylamino, diloweralkylamino, diloweralkylaminoalkyl, carboxy, carboalkoxy, acyl, carboxamido, loweralkylsulfoxide, acylamino, phenyl, benzyl, spirothiazolidinyl, phenoxy and benzyloxy; a and b represent points of attachment of residues Y and D respectively and a and b are in a peri relationship to one another on said fused A/B ring system; d and e represent points of fusion between ring A and ring B in said fused A/B ring system; D is an aryl or heteroaryl ring system, said ring system additionally substituted with from zero to four substituents chosen independently from halogen, -OH, loweralkyl, -O-loweralkyl, fluoroloweralkyl, -O-lowerfluoroalkyl, methylenedioxy, ethylenedioxy, alkoxy-Ioweralkyl, hydroxyloweralkyl, -CN, nitro, -S-loweralkyl, amino, loweralkylamino, diloweralkylamino, diloweralkylaminoalkyl, carboxy, carboalkoxy, acyl, carboxamido, loweralkylsulfoxide, acylamino, phenyl, benzyl, phenoxy and benzyloxy; Y is chosen from -CH2-, -O-, -OCH2-, -S-, -SO-, and -SO2-, wherein the left-hand bond indicated the point of attachment to ring A or B; M is chosen from aryl, substituted aryl, heterocyclyl, substituted heterocyclyl, C6 to C20 alkyl and substituted C6 to C20 alkyl; R1 is chosen from aryl, substituted aryl, heteroaryl, substituted heteroaryl and CF3; and when Y is CH2-, -O-, -S-, -SO-, or -SO2-, R1 may additionally be lower alkyl. Compounds of the invention are useful in the treatment of prostaglandin-mediated diseases.
Patent NZ-565511-A (NZ)
Title: Compositions and methods of treating disease with FGFR fusion proteins
Inventor: WILLIAMS LEWIS T
IPC: C07K14/71
Filed: 2006-07-24
Abstract: Disclosed is an FGFR fusion protein comprising a fusion partner and a FGFR polypeptide. The FGFR polypeptide consists of an extracellular domain of a FGFR protein, wherein the extracellular domain comprises a C-terminus, wherein the C-terminus comprises a variant of a wildtype FGFR extracellular domain C-terminus which comprises a deletion of 1 - 22 amino acid residues present in a wildtype FGFRl, FGFR2, FGFR3, or FGFR4 extracellular domain C-terminus. The FGFR fusion protein binds at least one FGF ligand or a biologically active fragment thereof. Compositions, vectors and recombinant host cells comprising the FGFR fusion protein are also disclosed as well as methods for producing the FGFR fusion protein.
Patent NZ-569985-A (NZ)
Title: Simulcast radio system using time slots
Inventor: HORN CLIVE DOUGLAS
IPC: H04J3/00
Filed: 2008-07-23
Abstract: A method of operating a simulcast radio system is disclosed. The method includes: allocating a radio channel having a channel frequency for broadcasting of signals between base stations and terminals, defining a frame having two or more time slots for use on the channel, setting up a call between two or more terminals in the system, transmitting data from a first base site to one or more terminals in the call, using the channel frequency and a first time slot in the frame, and transmitting the same data to one or more terminals in the call from a second base site adjacent the first site using the channel frequency and a second time slot in the frame.
Patent NZ-570081-A (NZ)
Title: Phosphopantetheinyl transferases from bacteria
Inventor: VALENTIN HENRY
IPC: C12N9/12
Filed: 2007-01-30
Abstract: Disclosed is an isolated polynucleotide comprising a sequence selected from the group consisting of: (a) a polynucleotide hybridizing to SEQ ID NO:6 or SEQ ID NO:8, or a complement thereof, under conditions of 5X SSC, 50% formamide and 42 degrees C, wherein the polynucleotide encodes polypeptide with phosphopantetheinyl transferase activity; (b) a polynucleotide encoding the polypeptide sequence of SEQ ID NO:5 or SEQ ID NO:7; and (c) a polynucleotide encoding a polypeptide with phosphopantetheinyl transferase activity and having at least 75% sequence identity to a polypeptide sequence of SEQ ID NO:5 or SEQ ID NO:7. Also disclosed are host cells, plants and seeds containing the said polynucleotide sequence. Also disclosed is a transgenic plant comprising a DNA molecule encoding a polypeptide having phosphopantetheinyl transferase activity operably linked to a promoter functional in said plant, wherein the DNA molecule comprises the said isolated polynucleotide sequence
Patent NZ-573656-A (NZ)
Title: Stomach held bolus string for animal dosing
Inventor: LEECH WAYNE FREDERICK
IPC: A61K9/00
Filed: 2011-02-07
Abstract: A treatment device 1, in particular to be swallowed by animals to treat intestinal parasites and worms, includes a plurality of discrete solid treatment devices 2, 3, 4, each in the form of a mini-bolus with a head 6 and a tail 7 shaped so that each mini-bolus can be partially nested together with adjacent boluses when the boluses are linked together by a flexible material 5 so that the treatment device forms a single articulated object that can be articulated in a plurality of different orientations. The boluses can be held together by a string passing through a hole through the body of each bolus or a tape along the sides of the boluses.
Patent NZ-576474-A (NZ)
Title: A printing system with individually controllable printing heads and continuous printing head positioning
Inventor: WRIGHT JEFFREY
IPC: B41J2/005
Filed: 2007-10-30
Abstract: A controller and a method for a coding and marking printing system are disclosed. The controller has a central processing unit and a second controller for driving a plurality of print heads for printing. The central processing unit provides a plurality of instructions for defining a plurality of instructions for the second controller to individually control the release of the ink of each print head nozzle according to an image and a determined dot formation representation of the image. The second controller includes a plurality of modules with each module having a print drive interface connectable to the print heads and a control system including encoder and printer logic core having core printer functions, and which through a jet drive interface communicates with a jet bank interface to drive the print heads. The printer logic core can control the initiation of the release and the time of the release of the ink of each print head nozzle. The printer logic core receives a rendered image and is connected to the print drive interface for controlling the print heads such that the control system initially receives the plurality of instructions of the rendered image from the central processing unit and individually controls each print head according to the inputted rendered image and a determined dot formation representation of the rendered image by logic and core printer functions without further recourse to the central processing unit.
Patent NZ-576879-A (NZ)
Title: Herbicide combinations containing amidosulphurones and a pyridine herbicide
Inventor: MARCELES PALMA VICTOR JOSE
IPC: A01N43/40
Filed: 2007-10-27
Abstract: Disclosed is an herbicide combination comprising components (A) and (B), where (A) denotes 1-(4,6-dimethoxypyrimidin-2-yl)-3-mesyl(methyl)sulfamoylurea (amidosulfuron) of the formula (I) and its salts and (B) denotes one or more herbicides selected from the group of the chloropyridines of the formula (II) and their salts and esters, in which R1 = is fluorine or chlorine, R2 = is H or chlorine, R3= is H or amino, and R4 = is COOH, OCH2COOH, OCH2COOCH(CH3)CH2O(CH2)3CH3 or OCH2COOCH(CH3)(CH2)5CH3, where at least one of the radicals R2 and R3 is different from H. Also disclosed is a method to control harmful plants that comprises applying said combination
Patent NZ-577821-A (NZ)
Title: Thioxanthene derivates useful to treat infectious diseases
Inventor: GIWERCMAN BIRGIT KJAELGAARD
IPC: A61P33/00
Filed: 2008-01-07
Abstract: Disclosed is the use of an anti-infective agent of formula (I) where the substituents are as disclosed in the description, in the manufacture of a medicament for the treatment or prophylaxis of an infectious disease, the medicament comprising 0.1 to 3000 mg of the anti-infective agent. Examples of compound of formula (I) include N-dealkyl-flupenthixol and N-dealkyl-clopenthixol. Also disclosed is the method of treating a non-human animal by administering a compound of formula (I). Further disclosed is a pharmaceutical composition comprising 0.1 to 3000 mg of an agent as defined by formula (I) and at least one pharmaceutically acceptable carrier or excipient, wherein said composition is in a unit dosage form.
Patent NZ-580394-A (NZ)
Title: Heteroaryl amide analogues as p2x7 antagonists
Inventor: IHLE DAVID
IPC: C07D519/00
Filed: 2008-04-09
Abstract: Disclosed are heteroaryl amide analogues of formula (I), wherein W-X-Y, Z?1-Z3, T, U and V are defined in the claims. The compounds are antagonists of the P2X7 receptor and can be used for the treatment of pain.
Patent NZ-581214-A (NZ)
Title: Processing audible and ultrasonic sound inputs using a sensor with a wide frequency response
Inventor: TURBAHN ODED
IPC: G06F3/033
Filed: 2008-04-18
Abstract: A method and an apparatus configured for processing of both audible and ultrasonic sound inputs are disclosed. The apparatus comprises a sensor with a frequency response spanning both audible and ultrasonic frequencies; and processing electronics configured to separate the audible and ultrasonic input frequencies for independent use. The processing electronics comprises a first filter (101) configured to filter audible frequencies and a second filter (101) configured to filter ultrasonic frequencies and a multiplexer for switching between the separated frequencies. The multiplexer allows for simultaneous processing of audible and ultrasonic output from the sensor. A system comprising the above described apparatus and a stylus configured to emit ultrasonic sound configured to emit ultrasonic sound is disclosed. This system can further comprises a touch-screen, in which placing a tip of the stylus on the touch-screen produces output corresponding to a location of the tip of the stylus on the touch-screen, and moving the tip of the stylus along the touch-screen surface produces output corresponding to the movement of the tip of the stylus along the touch-screen surface. A system comprising the above described apparatus and pointing device configured to emit ultrasonic sound is disclosed.
Patent NZ-585023-A (NZ)
Title: Manufactured seed having packing material
Inventor: HARTLE JEFFREY E
IPC: A01H4/00
Filed: 2008-09-25
Abstract: A manufactured seed that comprises: (a) a seed shell (20) housing a nutritive medium (26); (b) a cylcap (22), which is a restraint having a cavity (32) disposed within the seed shell; (c) a totipotent plant embryo (42) disposed within the cavity of the cylcap; (d) a fill material (120) disposed within the cavity of the cylcap; and (e) a seal disposed (43) on the seed shell to seal the embryo with the seed shell. The fill material is an adsorbent material that increases the surface area of the plant embryo that is in functional contact with the nutritive medium. The fill material can be activated charcoal.
Patent NZ-589061-A (NZ)
Title: Automatic configuration of inter-domain access technology neighbor relations
Inventor: RUNE JOHAN
IPC: H04W48/10
Filed: 2009-02-25
Abstract: Disclosed is a method of operating an Access Network Discovery and Selection Function (ANDSF) apparatus which receives neighbour relations reports from wireless terminals. The method includes automatically configuring a neighbor relations map based on neighbour relations data from the wireless terminals. The neighbor relations data can be data on non-domain cells neighboring a domain or non-domain cell, and/or domain cells neighboring a non-domain cell. Information maintained in the neighbor relations map includes extra-domain neighbor relations, each of which is a neighbour relation between a domain cell and its extra-domain neighbor and vice versa, and/or non-domain neighbor relations each of which is a neighbour relation between two non-domain neighbors. The step of automatically configuring the neighbor relations map includes providing steering instructions to the reporting terminals receiving the neighbor relations data from the reporting terminals; and updating the neighbor relations map based on the neighbor relations data from the reporting terminals, which data involves information of success and failure of access, handover or movement in idle mode. The steering instructions specify neighbor relations data recording and reporting behaviors of the reporting terminals. Further disclosed are the wireless terminals and ANDSF apparatus for use with the above method.
Patent NZ-590670-A (NZ)
Title: Key operated cylinder lock with spring biased pins for securing a shaft with a notch or head
Inventor: BURMESCH GARY
IPC: B60D1/02
Filed: 2009-08-25
Abstract: 590670 Disclosed is a locking device for a trailer hitch or coupling. The lock comprises a shaft having a first end, a second end, and a recessed portion between the first end and the second end and a locking head joined to the second end of the shaft, the locking head extending radially outward from the shaft. A lock body has a lock opening for receiving the first end of the shaft and a latch member is disposed within the lock body. An arcuate notch defines an arcuate edge portion spring biased radially inward of the lock opening to permit insertion of the first end of the shaft against the arcuate edge portion and past the latch member, and to engage the recessed portion of the shaft with the arcuate edge portion. A locking mechanism is disposed within the lock body, the locking mechanism including a locking member rotatable about a locking member axis between a locked condition and an unlocked condition, the locking member axis being substantially perpendicular to the shaft when the shaft is inserted in the lock opening. Rotation of the locking member from the locked condition to the unlocked condition rotates the latch member about the locking member axis to move the arcuate edge portion of the latch member out of engagement with the recessed portion of the shaft to permit withdrawal of the-first end of the shaft from the lock opening. The arcuate edge portion is rotationally spring biased radially inward of the lock opening.
Patent NZ-591141-A (NZ)
Title: Agricultural chemical composition and fruit bag
Inventor: NISHIMURA KAORU
IPC: A01N43/40
Filed: 2009-08-24
Abstract: Disclosed is an agricultural chemical composition comprising an agricultural chemical active ingredient A, an agricultural chemical active ingredient B, a sorbitan fatty acid ester and a wax, wherein the agricultural chemical active ingredient A is a neonicotinoid-based compound, preferably selected from the group consisting of nidenpyram, imidacloprid, acetamiprid, thiamethoxam, clothianidin and dinotefuran, and the agricultural chemical active ingredient B is an iminoctadine triacetate or an iminoctadine albesilate. A process for the production of said agricultural chemical composition is also disclosed, wherein the process comprises: mixing a heat-melted mixture of an agricultural chemical active ingredient A, an agricultural chemical active ingredient B and a sorbitan fatty acid, with a heat-melted wax, wherein the agricultural chemical active ingredient A is a neonicotinoid-based compound, and the agricultural chemical active ingredient B is an iminoctadine triacetate or an iminoctadine albesilate. A production process of an agricultural chemical sheet or a fruit bag is also disclosed, which comprises: melting said agricultural chemical composition by heating, and coating or impregnating the melt in paper, vinyl sheet or fabric.
Patent NZ-596790-A (NZ)
Title: Encapsulated switchgear
Inventor: HYRENBACH MAIK
IPC: H01B3/56
Filed: 2009-09-29
Abstract: An encapsulated switchgear (2) designed be operated in an environmentally friendly manner and which at the same time allows for a very simple and cost-effective design. The switchgear (2) has a housing (4) defining an insulating space (6) and an electrical active part (8) arranged in the insulating space (6). The insulating space (6) has an insulation medium with a dielectric compound having a boiling point of above -25°C and being a fluoroketone having from 4 to 12 carbon atoms.
Patent NZ-597769-A (NZ)
Title: Proteins and nucleic acids from meningitis/sepsis-associated Escherichia Coli
Inventor: PIZZA MARIAGRAZIA
IPC: A61K39/02
Filed: 2012-01-20
Abstract: Disclosed is the use of a peptide from a strain of E.coli responsible for neonatal meningitis (MNEC) and its related nucleic acid sequences, antibodies, medicaments and vaccines. The peptide can be used to treat infection by extraintestinal pathogenic E. coli (ExPEC), and meningitis/sepsis-associated E. coli infection.
Patent NZ-598557-A (NZ)
Title: Aptamers to tissue factor pathway inhibitor and their use as bleeding disorder therapeutics
Inventor: KURZ JEFFREY C
IPC: A61K48/00
Filed: 2010-08-17
Abstract: 598557 Disclosed is an aptamer or a salt thereof comprising the nucleic acid sequence set forth below: mG-mG-mA-mA-mU-mA-mU-mA-dC-mU-mU-mG-mG-dC-mU-dC-mG-mU-mU-mA-mG-mG-mU-mG-dC-mG-mU-mA-mU-mA-mU-mA-3T (SEQ ID NO: 2) (ARC17480), wherein "3T" is an inverted deoxythymidine, "dN" is a deoxynucleotide and "mN" is a 2'-OMe containing nucleotide.