baber/WOPTO huggingface dataset:
Patent EA-202091422-A1 (EA)
Title: Способ непрерывного производства продуктов на основе биспецифических антител
IPC: C07K16/28
Filed: 2018-12-11
Abstract: В настоящем изобретении предусмотрен способ непрерывного производства на этапе накопления для получения продуктов на основе биспецифических антител, содержащих по меньшей мере два связывающих домена. Способ включает, по меньшей мере, стадии (i) обеспечения в перфузионном биореакторе по меньшей мере одной культуры клеток млекопитающих, которая способна экспрессировать продукт на основе биспецифического антитела, (ii) выращивания культуры клеток млекопитающих при первой скорости перфузии до момента достижения заданного значения плотности жизнеспособных клеток и (iii) поддержания перфузионной культуры при второй скорости перфузии, где концентрацию продукта на основе биспецифического антитела в биореакторе поддерживают ниже порогового значения. Затем продукт на основе биспецифического антитела подвергают последующей обработке на этапе выделения и очистки. Более того, в настоящем изобретении предусмотрен продукт на основе биспецифического антитела, полученный с помощью способа непрерывного производства на этапе накопления.
Patent EA-202190459-A1 (EA)
Title: Способ и хроматографическая система для определения количества и чистоты мультимерного белка
IPC: G01N33/68
Filed: 2019-08-16
Abstract: Настоящее изобретение относится к хроматографической системе и способу оценки количества и/или чистоты мультимерного белка в образце, причем хроматографическая система предусматривает две разные матрицы для аффинной хроматографии, соединенные посредством переключающего клапана.
Patent EA-202190776-A1 (EA)
Title: Комбинация маломолекулярных ингибиторов cd-47 с другими противораковыми агентами
Filed: 2019-11-08
Abstract: Изобретение относится к композиции, содержащей агент, блокирующий CD47-SIRP, и один или более противораковых агентов, где агент, блокирующий CD47-SIRP, представлен соединением формулы (I). Изобретение также относится к способу лечения рака у субъекта путем введения терапевтически эффективного количества агента, блокирующего CD47-SIRP, представленного формулой (I), в комбинации с одним или более противораковыми агентами.
Patent ES-2159488-A1 (ES)
Title: Method for preparing pyrimidone derivatives with antifungal activity
Inventor: BARTROLI JAVIER
IPC: A61P31/10
Filed: 2000-03-07
Abstract: Process for the preparation of pyrimidone derivatives of formula I, which comprises reacting a compound of formula II with a compound of formula III in the presence of a base. The pyrimidone derivatives of formula I are useful as antifungal agents. < CHEM > < CHEM >
Patent ES-2180375-A1 (ES)
Title: Attachment device for adjustment mechanisms for vehicle external wing mirrors
Inventor: MENDOZA VICIOSO JOSE
IPC: B60R1/06
Filed: 2000-05-19
Abstract: Attachment device for adjustment mechanisms for vehicle external wing mirrors.This attachment device is applicable to adjustment mechanisms of the type that are comprised of a base body (1) adapted to house and hold a manual or automatic activation control device from the inside of the vehicle and of a cover containing the resources for attachment of a mirror holder plate that can be coupled to the base body (1) through a tab mode coupling, leaving the cover joined to the control device. The base body (1) and the chassis (2) of a vehicle external wing mirror are equipped with respective and additional first (3, 9) and second (13, 15) attachment organs that can be used alternatively or simultaneously.Applicable to the automobile industry.
Patent ES-2192948-A1 (ES)
Title: Sensor for measuring the firmness of fruit by impact.
Inventor: RUIZ ALTISENT MARGARITA
IPC: G01N3/307
Filed: 2001-07-20
Abstract: Sensor for measuring the firmness of fruit by impact.The invention consists of a sensor capable of making non-destructive measurements of the firmness of whole fruits in a classification line. The sensor is based on the response to the impact of a small hemispherical mass fixed to the end of a horizontal pivoting arm. The response of the fruit to the impact is measured by a miniature accelerometer mounted behind the impact head. The response to the impact consists of an acceleration-time signal during the time of contact between the impact head and the fruit. From analysis of this signal, a firmness index can be calculated. The impact arm is initially held by an electromagnet and is released by a spring when the electromagnet is switched off. The sensor, actuators and frame occupy a small space and the device can measure the firmness of at least 8 fruits per second and is thus suitable for use in a classification line.
Patent ES-2192984-A1 (ES)
Title: Method for preparing a candy having a stereoscopic picture by pad printing and a candy product prepared by using the same
Inventor: YOON JEONG MIN
IPC: A23G3/00
Filed: 2002-02-11
Abstract: The present invention relates to methods for preparing a candy having a stereoscopic picture therein comprising the step of pouring a measured amount of the first mixture, prepared by dissolving and concentrating the raw materials, for candy into a mold, while a temperature of the mixture is maintained at of about 130 to 150 DEG C. partially cooling the first mixture at about 30 to 45 DEG C. of its surface temperature printing desired pictures by using a pad printing method with one or more of black, yellow, red, and blue edible ink compositions onto the mixture at a temperature of about 15 to 25 DEG C. and a relative humidity of 40 to 60%, and then drying the mixture pouring a measured amount of the second mixture, prepared by dissolving and concentrating the raw materials, for candy into the mold atop the first mixture, while a temperature of the second mixture is maintained at about 120 to 135 DEG C. and cooling the resulting mixture.
Patent ES-2208129-A1 (ES)
Title: Stabilizer mixtures
Inventor: GUGUMUS FRANCOIS
IPC: C08K5/3462
Filed: 2001-05-22
Abstract: A stabilizer mixture containing (I) one low molecular weight alkylated sterically hindered amine compound and (II) one high molecular weight alkylated sterically hindered amine compound.
Patent ES-2247905-A1 (ES)
Title: Stucco plate manufacturing method, involves demolding plates by group shipper that is conformed by cross-sectional transferor, and evacuating shelves by dry stucco plates according to continuous process by group unloader
Inventor: MARTINEZ GARBAYO ALBERTO
IPC: B28B15/00
Filed: 2004-01-19
Abstract: The method involves incorporating a drying tunnel (8) with a series of shelves, which are being defined by respective transporting tapes. Plates (11) are demolded by a group shipper (7) that is fixed by a cross-sectional transferor (9). The shelves are evacuated by dry stucco plates according to a continuous process by a group unloader (14).
Patent ES-2242529-A1 (ES)
Title: Translator for translation of visual codification for disabled person, has sound reproduction unit adapted to receive electronic signals and to emit sonorous message to bar code based on result of processing of electronic signals
Inventor: CAMPOY CARMONA JUAN CARLOS
IPC: G09B21/00
Filed: 2004-04-20
Abstract: The translator has a codification reader (2), a conversion unit (3) for performing codification in electronic signals, and an electronic signals transmission unit (4). A programmable unit (5) is provided for processing of the electronic signals. The programmable unit includes a memory unit, in which average of codification is associated to a modifiable and rewriteable sonorous message. A sound reproduction unit is adapted to receive the electronic signals and to emit the sonorous message to a bar code based on result of the processing of the electronic signals.
Patent ES-2246714-A1 (ES)
Title: Multi-screen computer comprises field programmable gate array for processing compressed images that are received by communication adapter before displaying images on additional screen
Inventor: PARERA NUNEZ JORGE
IPC: G06F3/14
Filed: 2004-08-04
Abstract: The computer (1) comprises a communication adapter for receiving compressed images that are identical or different from images displayed on main screen (2). A field programmable gate array (FPGA) processes the received images before displaying the images on additional screen (6) in independent display device (3), and processes the data input by user through a module in the display device.
Patent ES-2255411-A1 (ES)
Title: Mutant g genes of the trout viral haemorrhagic septicaemia virus (vhsv) and applications thereof
Inventor: COLL MORALES JULIO
IPC: A61K35/13
Filed: 2004-08-27
Abstract: The invention relates to mutant G genes of viral haemorrhagic septicaemia virus (VHSV) in rainbow trout, which encode mutant G proteins of VHSV with defective or null binding to cells that can be infected by VHSV. Said mutant G genes of VHSV can be used, among other applications, to produce vaccines (DNA vaccines or attenuated live vaccines) for preventing disease caused by VHSV in animals that can be infected by VHSV, generating non-human transgenic animals, and developing reagents for the diagnosis of infection caused by VHSV.
Patent ES-2259560-A1 (ES)
Title: Cocoa powder processing system used in cocoa powder infusion machine, orients collector, which holds mixture of cocoa powder and water or milk, towards accessory conduit to direct discharge of cocoa mixture towards supply area
Inventor: LACASTA EGEA PEDRO JOSE
IPC: A47J31/40
Filed: 2005-03-23
Abstract: The system orients a collector, which holds a mixture of cocoa powder and water or milk, towards an accessory conduit to direct the discharge of cocoa mixture towards a supply area for the prepared cocoa product. The cocoa powder and water or milk are discharged from corresponding storage containers.
Patent ES-2322732-A1 (ES)
Title: Flag pole with revolving truck which returns to its starting position
Inventor: ARCOS REPISO VICENTE
IPC: E04H12/32
Filed: 2006-06-02
Abstract: The invention is composed of 4 semicircular magnets which are coupled, forming two circular arcs. One of these is placed in the end of the flagpole and the other in the truck, which revolves freely. When the wind stops the magnets are attracted and the truck and the flag it is holding turn to the predetermined starting position.
Patent ES-2324069-A1 (ES)
Title: Parking brake for use in brake system of vehicle, has lever apparatus operated by actuator and exerting force on control wire, where force is transferred from control wire to brake unit and brings brake unit into parking brake position
Inventor: ULMANN PETER
IPC: B60T7/10
Filed: 2006-09-05
Abstract: The brake has an actuator (2), a lever apparatus (7) and a control wire (12), which is connected with a brake unit of the brake and the lever apparatus. The lever apparatus is operated by the actuator and exerts a force on the control wire, where the force is transferred from the control wire to the brake unit and brings the brake unit into a parking brake position. Guide rollers are arranged between two sides (8, 9) of the lever apparatus and the control wire and are rotatably arranged in the sides. An independent claim is also included for a brake system of a vehicle with a parking brake.
Patent ES-2319153-A1 (ES)
Title: Wind turbine installation method and tool
Inventor: CHRISTENSEN MOGENS
IPC: F03D1/00
Filed: 2007-09-19
Abstract: The invention relates to a method for installing a wind turbine (1) that does not require the use of large cranes. The invention comprises the use of a supporting element (8) including: four legs (9), an upper element (10) for coupling same to a tower (5), a set of pulleys and two pivoting connectors. The wind turbine (1) is first assembled on the ground and then raised until the tower (5) is connected to the pivoting connectors of the supporting element (8), the latter step being performed using a capstan which pulls a cable (11) connected to means (6) for securing same to the tower (5) and which extends through the set of pulleys of the supporting element (8). Subsequently, another cable and a capstan located on the foundation (7) of the tower (5) are used to turn the wind turbine (1) until the base of the tower (5) is connected to the foundation (7) and the wind turbine (1) is connected to the supporting element (8).
Patent ES-2335075-A1 (ES)
Title: Materno-foetal monitoring system for remote diagnosis
Inventor: ELENA PEREZ MARIA DEL MAR
IPC: A61B5/344
Filed: 2008-09-15
Abstract: It has a local subsystem (6) which provides clean signals of the electrocardiograms relating to the foetus and the mother and is connected, via a communication network (7), to a monitoring centre (8) which can receive a plurality of signals from various local subsystems (6) and makes them available to corresponding medical centres or terminals (10) via a data network (9). Each local subsystem (6) has a capture device (1), which is composed of sensors (2) connected to a monitoring chip (3) and is accommodated in a textile carrier or band which can be applied to the pregnant woman, and a portable patient terminal (5) connected to the chip (3) and to the communication network (7).
Patent ES-2358142-A1 (ES)
Title: Method, system and computer program for obtaining the transformation of an image
Inventor: DE LOS AIRES ALVAREZ XAVIER
IPC: G06T3/00
Filed: 2009-10-21
Abstract: The invention relates to a system for obtaining the transformation (30) of an image, said system comprising means for capturing image proportions means for capturing the width of the transformation means for capturing the height of the virtual representation of the image means for establishing coordinate axes at the point on the surface, onto which the viewing point is orthogonally projected means for obtaining a first transformation angle (+-) from two parameters: the distance between the point on the surface onto which the viewing point is projected and the upper end furthest from the transformation and the distance corresponding to the coordinate of the upper end furthest from the transformation in relation to said viewing point, and the distance corresponding to the coordinate of the upper end furthest from the transformation in relation to the viewing point means for obtaining the lateral transformation longitude (L3) from the first transformation angle and the transformation width means for obtaining the longitude (L4) of the transformation (30) from the captured proportions and height of the virtual representation means for obtaining a second transformation angle ( ) from two parameters: the distance between the point on the surface onto which the viewing point is projected and the lower end closest to the transformation and the distance corresponding to the coordinate of the lower end closest to the transformation.
Patent ES-2383424-A1 (ES)
Title: Aircraft frame and method for obtaining it
Inventor: PINA LOPEZ JOSE MARIA
IPC: B64C1/06
Filed: 2009-09-29
Abstract: Aircraft frames and method for obtaining them, which frames are being made of composite material, and they comprise several partitions (20) that form, when joined, the aforementioned frame in its entirety, with these partitions (20) comprising sections (1) with a length (2), and sections (1) that are being arranged on the inside of the skin (3) that forms the fuselage of the aircraft. This fuselage is integrally embodied in a single piece, with the length (2) of the sections (1) being the maximum possible, in such a way that the maximum separation (5) between the frame section (1) and the skin (3), with said separation (5) being measured by the inside of the aforementioned skin (3), is lower than the limit value permitted for the use of sealant in liquid state.
Patent ES-2357063-A1 (ES)
Title: System for protecting wind turbines against atmospheric discharges
Inventor: ALMAZAN SANCHEZ JESUS
IPC: F03D11/00
Filed: 2009-10-06
Abstract: By means of a series of parameters taken by the plurality of sensors, the system of the invention makes it possible, via a central control unit provided with complementary programming firmware, to activate an electric-field compensating device (7) whenever there is a risk of lightning discharging over the wind turbine, in such a manner that, in the contrary case, said device remains inoperative. The electric-field compensating device (7) is associated not only with the nacelle (2) but also with the tower (1) and the blades (4) in such a manner that, between the rotor (3) and the nacelle unit (2) there is a first pair of rings (14), which are conducting, concentric and the dielectric of which is air, whilst, in the lower zone of the nacelle unit (2) there is a second pair of conducting rings (15) with similar features.
Patent ES-2365317-A1 (ES)
Title: Prosthetic band, in particular for repairing a mitral valve
Inventor: RUYRA BALIARDA XAVIER
IPC: A61F2/24
Filed: 2010-03-19
Abstract: Prosthetic band (1), in particular for repairing a mitral valve, comprising an elongate band (2) made of a flexible material for the fixation of artificial cords, and including a plurality of separable pads (4) that are joined along the trajectory of said elongate band (2) and protrude with respect thereto, said pads (4) being separated from each other and capable of receiving such artificial cords. In this way, the proper length of the artificial cords can be established, and they can be tied without slippage of the knots with the aim of applying them during an operation for the repair of a prolapse of the mitral valve
Patent JO-P20210256-A1 (JO)
Title: Bioconjugates of e. coli o-antigen polysaccharides, methods of production thereof, and methods of use thereof
Inventor: ABBANAT DARREN ROBERT
Filed: 2020-03-18
Abstract: A bioconjugate of an E. coli glucosylated O4 antigen polysaccharide covalently linked to a carrier protein and compositions thereof are provided. Also provided are recombinant host cells for producing the bioconjugate, and methods of producing the bioconjugate using the recombinant host cells. The recombinant host cells contain a nucleic acid encoding a glucosyl transferase capable of modifying the E. coli O4 antigen with glucose branching to produce the glucosylated O4 antigen polysaccharide. Bioconjugates of an E. coli glucosylated O4 antigen polysaccharide described herein can be used alone or in combination with one or more additional E. coli O-antigen polysaccharides to induce antibodies against an E. coli glucosylated antigen, and to vaccinate a subject against extra-intestinal pathogenic E. coli (ExPEC).
Patent SG-90758-A1 (SG)
Title: Sensor for the detection of a predetermined filling level of a container
Inventor: GUNTHER THOMAS
IPC: G01F23/26
Filed: 2000-11-01
Abstract: Sensor comprises three capacitor electrodes (5-7) arranged in parallel planes with a hole passing through the capacitor plates for a fluid container (1), the fluid level of which is to be measured. First and second capacitors (8, 9) formed between the three plates form part of first and second RC- members. The latter have different time constants and level measurement is by use of relative alteration of the two time constants, so that the sensors do not require setting or calibrating prior to use.
Patent SG-111913-A1 (SG)
Title: Interactive display system
Inventor: JULIAN GORING ARCHDALE ELLISON
IPC: H04N7/173
Filed: 1998-04-30
Abstract: An interactive display apparatus comprises an audio subsystem (4), a control subsystem (5) and a plurality of video subsystems (2, 3). The video subsystems (2, 3) have access locally to image data, including image files and live video. The video subsystems (2, 3) are controlled by the control subsystem (5) which then sends command messages to the video subsystems (2, 3). A person watching the display (22, 42) of one of the video subsystems (2, 3) can dial into the audio subsystem (4) and thereby control the operation of the video subsystem (2, 3). To do this, the audio subsystem (4) notifies the control subsystem (5) of incoming audio command signals. It is to be noted that when the system is on line, the control subsystem (5) does not transfer image data to the video subsystem (2, 3) but merely sends commands setting the format of the images displayed on the screens (22, 42). <IMAGE>
Patent SG-121888-A1 (SG)
Title: Knife
Inventor: DUMS ROLF
IPC: B26B9/02
Filed: 2004-05-28
Abstract: Knife (1), especially a household knife, comprises a cutting region (3) provided with an undulating section (6) and two knife surfaces (3a), each extending along one side of a central plane. The undulating section has recesses (6a, 6b) molded on both sides of the central plane alternately in one or the other knife surface. The recesses extend from one knife surface in the direction of the other knife surface as far as the central plane to form a cutting edge (5) that runs toward and away from the knife surface. Preferred Features: The recesses are rounded.
Patent SG-128532-A1 (SG)
Title: Power generator
Inventor: CHING-HUI KUO
Filed: 2005-08-18
Abstract: A power generator using batteries to drive the generator to rotate for power generation, and using the generated power to recharge the batteries is provided. The power generator includes a battery set to provide power to rotate a starting motor. The starting motor is connected to a first link device, which is connected to a first generator. The rotation of the starting motor enables, through the first link device, the rotation of the first generator to generate power for other electrical devices. The first generator, through a second link device, enables a second generator to rotate and generates power when the first generator is in operation. The power generated by the second generator recharges the battery set so that the power generation efficiency is improved.
Patent AR-022233-A1 (AR)
Title: Cable de fibras opticas
IPC: G02B6/44
Filed: 2000-01-10
Abstract: Cable de fibras opticas para aplicacion en instalaciones de líneas de alta tension, en el cual se ha aplicado sobre la camisa de cable (KM) una capapelicular (KS) resistente al efecto corona.
Patent AR-020024-A1 (AR)
Title: Composiciones para lavar platos que contienen agentes tensoactivos de bencensulfonato de alquilo
IPC: C11D1/22
Filed: 2000-01-19
Abstract: Una composicion para lavar platos a mano que comprende: i) desde aproximadamente 0,01% hasta aproximadamente 99,99% en peso de una composicion de unamezcla de agente tensoactivo: un sistema de agente tensoactivo de sulfonato de alquilarilo que comprende por lo menos dos agentes tensoactivos de sulfonato dealquilarilo que tiene la formula (1) en la cual L es un hidrocarbilo alifático acíclico de 6 a 18 átomos de carbono en total; M es un cation o una mezcla decationes y q es la valencia de los mismos; a y b son numeros seleccionados de modo que dicho agente tensoactivo de sulfonato de alquilarilo es electroneutro;R está seleccionado entre H y alquilo C1 a 3; R está seleccionado entre H y alquilo C1-3; R está seleccionado entre H y alquilo C1a 3; ambos R y Restán adheridos en forma no terminal a L y por lo menos uno de R y R es alquilo C1 a 3 y A es arilo; donde dicho sistema de agente tensoactivo de sulfonatode alquilarilo comprende dos o más isomeros con respecto a las posiciones de adhesion de R1. R y A a L; en por lo menos aproximadamente 60% de dicho sistemade agente tensoactivo de sulfonato de alquilarilo, A está unido a L en una posicion que está seleccionada entre las posiciones alfa- y beta - a cualquiera delos dos átomosde carbono terminales de L; y donde adicionalmente dicho sistema de agente tensoactivo de sulfonato de alquilarilo tiene por lo menos una de lassiguientes propiedades: dicho sistema de agente tensoactivo de sulfonato de alquilarilo tiene una relacionde átomos de carbono no cuaternarios a cuaternariosen L de por lo menos aproximadamente 5:1 en peso, cuando dichos átomos de carbono cuaternarios están presentes; o el porcentaje de biodegradacion medidomediante el ensayo SCAS modificado, que excedeel bensulfonato de tetrapropileno; ii) desde aproximadamente 0,0001% hasta aproximadamente 99,99% en peso de lacomposicion de un agregado para lavar platos a mano convencional; y iii) desde aproximadamente 0,01% hasta aproximadamente 7% en peso de la composicion deunion divalente seleccionado del grupo que consiste en magnesio, calcio y mezclas de los mismos.