baber/WOPTO huggingface dataset:
Patent EP-2261336-B1 (EP)
Inventor: FIEBIG HELMUT PROF
IPC: A61K38/095
Filed: 2004-12-01
Granted: 2013-10-16
Abstract: DNA molecules (I), corresponding to the sequence of the major allergens of cereal pollen are new. (I) have sequences (1; 1603 nucleotides (nt)); (3; 1644 nt); (5; 1608 nt); (7; 1603 nt) or (9; 1603 nt), all reproduced. DNA molecules (I), corresponding to the sequence of the major allergens of cereal pollen comprise sequences comprising 1603 nucleotides (SEQ ID No.:1) (nt)); 1644 nucleotides (SEQ ID No.:3; ); 1608 nucleotides (SEQ ID No.:5; ); 1603 nucleotides (SEQ ID No.:7; ) or 1603 nucleotides (SEQ ID No.:9; ). Independent claims are also included for: (1) DNA (Ia) that hybridizes to (I) under stringent conditions and is derived from DNA of Poaceae; (2) DNA (Ib) that encodes a polypeptide that is immunologically cross-reactive with the major allergens Sec c 4 ( Secale cereale); Hor v 4 ( Hordeum vulgare) or Tri a 4 ( Triticum aestivum) and derived from Poaceae; (3) DNA fragment, or combination of fragments, of (I), (Ia) or (Ib) that encodes an immunomodulatory T-cell reactive fragment (X) of Group 4 Poaceae allergens; (4) a DNA corresponding to any of the new DNAs or fragments that encodes an (X) but is modified by targeted mutation of individual codons, deletion or addition; (5) recombinant DNA expression vector or cloning system containing any of the new DNAs linked to expression control sequences; (6) host organism transformed with any of the new DNAs or the vector of (5); (7) preparing a polypeptide (II) encoded by the new DNAs by culturing the organisms of (6); and (8) (II) having any of the sequences, comprising 518 amino acids (SEQ ID No.:2; 520 amino acids (SEQ ID No.:4; ); 518 amino acids (SEQ ID No.:6; ); 518 amino acids (SEQ ID No.:8) or 518 amino acids (SEQ ID No.: 10; ) or their mature forms. ACTIVITY : Antiallergic. No biological data given. MECHANISM OF ACTION : Vaccine.
Patent EP-2202340-B1 (EP)
Inventor: SCHNEIDER UWE
IPC: B32B5/26
Filed: 2004-06-02
Granted: 2011-08-17
Abstract: An apparatus and method for producing an elastomeric nonwoven laminate including a plurality of elastic strands joined to a nonwoven web in a controlled distribution is provided. The apparatus includes an extruder for extruding a plurality of elastic strands onto a cooled surface of a rotating drum, which transports the strands in parallel alignment to a nip formed between two rollers rotating about parallel axis. The drum transfers the plurality of strands to the nip in a controlled distribution where it is bonded with the nonwoven.
Patent EP-2280070-B1 (EP)
Inventor: KAY MARK
IPC: C12Q1/68
Filed: 2002-07-19
Granted: 2015-05-20
Abstract: Methods and compositions are provided for modulating, e.g., reducing, coding sequence expression in mammals. In the subject methods, an effective amount of an RNAi agent, e.g., an interfering ribonucleic acid (such as an siRNA or shRNA) or a transcription template thereof, e.g., a DNA encoding an shRNA, is administered to a non-embryonic mammal, e.g., via a hydrodynamic administration protocol. Also provided are RNAi agent pharmaceutical preparations for use in the subject methods. The subject methods and compositions find use in a variety of different applications, including academic and therapeutic applications.
Patent EP-2415317-B1 (EP)
Inventor: HULTHEN PER
IPC: H04W16/14
Filed: 2010-03-30
Granted: 2013-11-20
Abstract: The present invention relates to a method for selecting operating frequency channels having frequency parameters, such as a frequency interval or at least one carrier frequency, for a network communicating data over a shared medium. The network is configured to communicate within a frequency range, and the frequency range is divided into a plurality of frequency channels f1-fn, each frequency channel defines a predetermined frequency parameter. The data to be communicated over the network is divided into sequences FS, each sequence having a plurality of positions SP1-SPm. The method further comprises regularly scanning the frequency range to identify interfering frequencies generated by interfering networks operating within said shared medium, and assigning a frequency channel fk to each position SPi within the sequences FS based on the identified interfering frequencies, whereby the use of interfering frequencies is limited.
Patent EP-2504089-B1 (EP)
Inventor: VON BRIEL UWE
IPC: B01F7/00
Filed: 2010-11-04
Granted: 2013-11-20
Abstract: Example apparatus and methods for homogenizing liquid manure in a cesspool are disclosed. One example device includes a pontoon to float in or on the liquid manure and a stirring unit held on the pontoon and to be immersed in the liquid manure. The example stirring unit includes a first stirring screw to rotate around a first rotational axis and a second stirring screw to rotate around a second rotational axis. The example first and second stirring screws are oriented such that the first rotational and the second rotational axis are substantially orthogonal to a direction of motion of the pontoon.
Patent EP-2333811-B1 (EP)
Inventor: SUZUKI YOSHIKAZU
IPC: G05F1/02
Filed: 2005-07-25
Granted: 2012-05-09
Abstract: To positionally stabilize the arc spot in a super-high pressure discharge lamp which is filled with at least 0.20 mg/mm 3  of mercury and to prevent the formation of so-called flicker, in an operation device having a high pressure discharge lamp and a feed device, the feed device of the high pressure discharge lamp supplies a frequency in the range from 60 Hz to 1000 Hz as the stationary operating frequency and a low frequency, in a frequency range of from 5 Hz to 200 Hz is inserted which has an insertion length of from one half period to five periods, and an inserting period of from 0.01 seconds to 120 seconds, into the alternating current of the stationary operating frequency. Furthermore, insertion length of the low frequency is changed according to changes of the operating voltage of the discharge lamp.
Patent EP-2529787-B1 (EP)
Inventor: BLOMQVIST ANDREAS
IPC: A61N1/362
Filed: 2011-05-31
Granted: 2014-01-29
Abstract: The present invention relates generally to implantable medical devices and more particularly to systems and methods for stimulating a heart of a patient. At least one left atrial pressure, LAP, signal over a cardiac cycle is obtained. The A-wave is identified using the LAP signal and a maximum positive rate of change of the A-wave of the LAP signal is determined. The maximum positive rate of change of the A-wave corresponds to the rate which the pressure in the atrium raises as the atria contraction forces more blood into the ventricle during the very last stage of diastole. Further, AV and/or VV delay is adjusted in response to the maximum positive rate of change of the A-wave, wherein a reduction of the maximum positive rate of change of the A-wave indicates an AV and/or VV delay providing an enhanced hemodynamic performance.
Patent EP-0010146-B1 (EP)
IPC: F42D5/04
Filed: 1979-08-31
Granted: 1981-12-02
Abstract: 1. A protective mat for covering articles which are to be explosively blasted, characterized in that it consists of a nonwoven textile sheet-like structure of synthetic continuous filaments or staple fibres, which on determination of the tension-elongation behaviour according to DIN 53857 has a tensile strength of 30-100 n/5 cm at 10 % elongation, a tensile strength of 100-400 N/5 cm at 30 % elongation, a tensile strength of 300-800 N/5 cm at 50 % elongation, a tensile strength of 500-950 N/5 cm at 70 % elongation and a tensile strength of 600-1100 N/5 cm at 90 % elongation, and a weight per unit area of at most 800 g/m**2, or that it consists of a plurality of such nonwoven textile sheet-like structures joined side by bonding, such as welding or stitching.
Patent EP-0015291-B1 (EP)
Title: Piece de raccordement pour fibres optiques
IPC: G02B6/24
Filed: 1980-04-08
Granted: 1984-02-15
Abstract: Une piece de raccordement pour tenir en alignement axial le long d'une direction axiale une paire de fibres optiques (22) avec les extremites de fibres optiques en relation bout a bout, comprend une paire de pieces de support de fibres (13). Chaque piece de support (13) possede au moins un canal, incline, en forme de V en alignement axial pour se conformer a la fibre (22) et des moyens (15) pour tenir ces dites fibres avec les extremites depassant d'une longueur predeterminee depuis l'extremite du canal incline, en forme de V, respectif (21). Une piece separee pour la reception des fibres (17) possede une region pour la jonction des fibres (29) comprenant au moins un canal en forme de V (31) de longueur suffisante ayant une section de niveau dans la region pour la jonction afin de supporter lesdites fibres qui depassent (22) en relation bout a bout. Les canaux inclines en forme de V (21) respectifs desdites pieces de support (13) etant inclines vers le bas le long d'une direction axiale vers cette region de jonction (29) pour forcer les fibres vers le bas dans la section de niveau. La piece receptrice (19) presente une partie receptacle (39) et chacune desdites pieces de support (13) ont une surface extreme et une paire de fourches (37) qui en depassent vers l'exterieur en direction axiale. Les fourches respectives (37) de l'une des pieces de support (1) sont en relation d'aboutement dans ledit receptacle (39) avec les fourches respectives de l'autre piece de support (17) de maniere a ce que les pieces de support (17) soient positionnees en d'opposition assemblee a ladite piece receptrice de fibre (19) alors que lesdits canaux inclines respectifs (21) sont alignes avec ladite section de niveau dudit canal de chaque cote de celui-ci. Un moyen transversal amovible est fourni pour engager les fibres respectives (22) dans ladite section de niveau du canal en forme de V (31).
Patent EP-0021244-B1 (EP)
IPC: C07J41/00
Filed: 1980-06-10
Granted: 1983-01-12
Abstract: The present invention provides 12-dehydrodigoxin oximes of the general formula:   <IMAGE>   wherein R1 and R2, which can be the same or different, are hydrogen atoms, lower acyl radicals or lower alkyl radicals or R1 and R2 together can represent an alkylidene radical containing 2 to 6 carbon atoms and R3 is a hydrogen atom or a lower alkyl or aralkyl radical. The present invention also provides a process for the preparation of these oximes and pharmaceutical compositions containing them and is also concerned with the use of these oximes for the preparation of pharmaceuticals for the treatment of cardiac insufficiency.
Patent EP-0024364-B1 (EP)
Title: Retaining device for a cell in an electronic wrist-watch
IPC: H01M2/10
Filed: 1980-08-04
Granted: 1984-02-01
Abstract: A battery is placed in a recess in the plate of an electronic wrist watch movement. The battery cover presses against a spring contact fixed to a plate bearing a printed circuit. An insulating sheet insulates the battery from an inner flange of the movement plate. Disposed on the bottom of the battery casing is a pressure bracket having arms which resiliently grip the sidewall of the casing. Resilient radial tongues of the bracket are bent so as to be in contact with the back of the watch case which presses against the assembly at the time of casing-up so as to hold the battery in place. The connection to ground is established by a contact part and a screw, as well as by the contact between the battery casing and the movement plate and via the back of the watch case.
Patent EP-0050793-B1 (EP)
IPC: A61K9/00
Filed: 1981-10-14
Granted: 1984-06-13
Abstract: A synthetic protein-free lung surfactant composition is utilized to temporarily substitute for natural lung surfactant in the mammalian lung where such natural lung surfactant is absent or in low concentration. The synthetic surfactant composition consists essentially of a major amount of 1,2-dipalmitoyl-sn-3-glycerophosphoryl choline (DPPC), and a minor amount of a fatty alcohol, preferably a fatty alcohol having from 14 to 18 carbon atoms, and especially n-hexdecan-1-ol. The synthetic surfactant composition is administered directly into the lungs of a distressed subject to create a film on the alveolar interfacial surfaces and reduce surface tension. Expansion of the alveolar spaces is thereby facilitated.
Patent EP-0054801-B1 (EP)
IPC: A61K35/74
Filed: 1981-12-04
Granted: 1985-04-10
Abstract: An antibiotic AM-5344-A2 substance, and a process for the preparation of the antibiotic AM-5344-A2 substance are described. The antibiotic AM-5344-A2 substance is prepared by cultivating an AM-5344-A2 substance-producing strain belonging to the genus Streptomyces, for example, Streptomyces sp. Am-5344 in a nutrient medium, and recovering the Am-5344-A2 substance from the culture.
Patent EP-0048048-B1 (EP)
IPC: B01J8/18
Filed: 1981-08-27
Granted: 1983-05-11
Abstract: Heat exchanger having a plurality of vertical pipes for upward passage of a first heat-exchanging medium, at least one compartment for passage of a second heat-exchanging medium through which compartment said pipes extend, a lower chamber through which said first medium passes and into which said pipes open for admission to the pipes of said first medium, and a flow distribution element adapted to distribute the flow of said first medium in said lower chamber to the pipes. A fluidizable particulate material is in operation, is maintained in a fluidized state in the pipes by the flow of the first medium. The pipes have inlet elements extending downwardly into said lower chamber with their lowermost ends open. Stabilization openings are provided into said inlet elements above said open lowermost ends thereof. To prevent blocking of the stabilization openings by dirt, these are separated, outside the inlet elements, from the said open lowermost ends of the inlet elements by at least one screen which allows flow of the first medium to the stabilization openings.
Patent EP-0051455-B1 (EP)
IPC: B65D71/00
Filed: 1981-10-29
Granted: 1985-01-30
Abstract: For use primarily in article carriers, interlocking structure for securing a pair of face contacting overlapping panels in interlocked relation includes a locking aperture formed in one of the panels and having an anchoring edge and a spaced securing edge disposed in generally parallel relation and including side edges together with a locking tab having a body portion, a heel portion, and a toe portion and being struck from the other of said panels and folded through an angle of approximately 180 DEG  toward an adjacent edge thereof and into face contacting relation with the part of the other panel which is disposed adjacent the edge thereof and so as to cause the heel portion to enter the locking aperture and to engage the anchoring edge and to cause the toe portion to enter the locking aperture adjacent the securing edge.
Patent EP-0100787-B1 (EP)
IPC: B23K9/20
Filed: 1982-08-16
Granted: 1988-01-07
Abstract: 1. A stud welding process comprising tip initiation between a stud (5) and a workpiece with a welding head with a pressure device (61) with a spring (62) presettable to an initial spring force (Ko) for pressing the tip (52) of the stud (5) from a presettable distance (do) onto a workpiece surface (53) and with a welding cable (31), which connects the stud (5) to a welding capacitor arrangement (C1, C2, C3) via switching means (TH1) corresponding to an adjustable preselected capacitance (Cv, Mu1), which welding capacitor arrangement (C1, C2, C3) is to be connected on the other side with the workpiece and which is chargeable by means of an adjustable charging device (Tr) to the initial welding-arc voltage (Uo), characterized in that the welding head comprises measuring means (RMi, 70) for recording the time behaviour of welding signals, that is of the welding current (I(t)), the welding arc voltage (U(t)) and the stud shaft path (d), the signals from which measuring means are conveyed to a measured value analyzer in a control device (MP), which derives the following characteristic values (Mw) therefrom, a tip contact time t0 , a tip explosion time t1 , a stud short-circuit time t2 , a maximum current time tm , a stud melting penetration depth d3 , a stud shaft rebound path d4 and continuity of current behaviour, and supplies the characteristic values to the control device (MP), which compares these characteristic values or combinations thereof with previously input recommended values or with values derived during previous welding for these characteristic values (Mw) or combinations (t2 -t1 ; t1 -t0 ; d3 +d4 ) thereof and calculates from this comparison via tendential allocations, determined previously by series of tests, analyses and mathematical evaluation, between a characteristic value (Mw) or one of the combinations and a correcting variable (BP; Ko, Cv, Uo) and the measured point contained therein of the optimum welding result an alteration of the correcting variables (BP) in existence at the time of measurement for the initial spring force (Ko), the capacitance (C1, C2, C3) and the initial welding arc voltage (Uo), which it transmits directly or indirectly for the subsequent welding to the corresponding correction devices for spring adjustment (67), capacitance preselection (Mu1) and charging devices (Tr).
Patent EP-0080120-B1 (EP)
IPC: B31F1/00
Filed: 1982-11-11
Granted: 1986-03-26
Abstract: Disclosed is a process and apparatus for forming a tube from a flat web by overlapping the edge zones of the web with one another or with a flexible strip while maintaining distance between the adhering, overlapping surfaces in order to provide horizontally straight edges, and thus a circumferentially constant diameter.
Patent EP-0070587-B1 (EP)
Title: Rinse aid composition
IPC: C11D17/00
Filed: 1982-07-01
Granted: 1985-11-06
Abstract: A liquid rinse aid for use in automatic dishwashing machines comprises a low foaming ethoxylated nonionic surfactant, an organic chelating agent, a hydrotrope-water solubilizing system and 0.1-10%, by weight of the rinse aid, of magnesium, zinc, tin, bismuth or titanium ions, added in the form of a water soluble salt.
Patent EP-0060097-B1 (EP)
Title: Split phase stereophonic sound synthesizer
IPC: H04S5/00
Filed: 1982-03-04
Granted: 1985-01-09
Abstract: A stereophonic sound synthesizer system is presented which utilizes a phase splitter in the form of a transformer to develop two oppositely phased audio signals from an applied monaural signal. One of the two oppositely phased signals is applied to a transfer function circuit of the form H(s), which modulates the intensity of a monaural signal as a function of the frequency. The intensity modulated H(s) signal may be applied to an amplifier for subsequent amplification and reproduction. The H(s) signal is also combined with the other of the two oppositely phased signals to produce a difference signal which is the complement of the H(s) signal. The difference signal may be applied to an amplifier for subsequent amplification and reproduction. No differential amplifier is necessary to produce the difference signal because the necessary selective phase opposition of the signals combined in that channel is provided by the use of the oppositely phased transformer output signals. In addition, the transformer electrically isolates the television's electrical system from the stereo synthesizer system's signal outputs.
Patent EP-0065943-B1 (EP)
IPC: B22D41/02
Filed: 1982-05-19
Granted: 1986-10-08
Abstract: 1. A method of realizing the inner lining of the tap hole of a metallurgical container, especially when the latter has a very great diameter, e.g. greater than 300 mm, characterized by the following steps : (a) achieving the inner refractory lining (13) of the metallurgical container at least up to the portion thereof (14) located at the upper level of the tap hole to be formed, (b) core drilling a hole (1) through the mass (14) of said refractory lining located where the tap hole has to be formed, (c) placing inner sleeves (16) inside the drilled hole (1) by using centring means, and (d) introducing pise ou clay (17) having a sufficient refractoriness into the space between the outer surface of the sleeve (16) and the wall (18) of the drilled hole (1).
Patent EP-0090334-B1 (EP)
IPC: F16L59/00
Filed: 1983-03-22
Granted: 1986-11-12
Abstract: An improved method and apparatus for fabricating mobile cryogenic storage vessels insulated with fiberglass batting, a layer of which is non-compressively secured to the outer shell and to the inner vessel in such manner as to fill all spaces between the support members so as to leave an annular evacuable space between the layers of insulation.
Patent EP-0096852-B1 (EP)
IPC: B02C25/00
Filed: 1983-06-09
Granted: 1986-01-15
Abstract: 1. A bow mill with vertical axis, the bowl rotating relative to means (4) pressing the material against the surface of the bowl (1) and being controlled by hydraulic cylinders (9), with a control and adjusting circuit depending on the material to be ground, comprising a means (20) for indicating the rate at which materials is being fed into the mill and a means (24) for indicating the pressure of the hydraulic fluid in the cylinders, characterized in that it further comprises a means (22) for indicating the power absorbed by the mill, a means (21) for indicating the height of the layer of material between the pressing means and the bowl, and (19, 17) for sensing the data of the indicating means in order to maintain a variation of the height of the layer of material according to the throughput rate of the mill according to a predetermined linear law between 30 % and 100 % of the maximum throughput rate.
Patent EP-0114193-B1 (EP)
Title: Ceramic substrate
IPC: H01L23/14
Filed: 1983-09-29
Granted: 1986-06-18
Abstract: A heat conductive ceramic substrate for semiconductor circuits, comprising polycrystalline aluminum nitride of high density containing as an additive boron nitride or oxides of calcium, magnesium, aluminum, titanium, zirconium, chrome, silicon, and/or rare earth metals. The boron nitride additive concentration ranges between 0.1 and 3% by weight, preferably between 0.5 and 2% by weight. The oxide additive concentration ranges between 0.1 and 5% by weight. The substrate has a significantly higher thermal conductivity than aluminum oxide substrates and is more economincal to manufacture than beryllium oxide substrates.
Patent EP-0115613-B1 (EP)
IPC: A61K38/21
Filed: 1983-12-20
Granted: 1991-03-27
Abstract: The present invention relates to the combination of the promoter/operator region of the tryptophan operon of Serratia marcescens with a synthetic ribosome binding sequence, an expression plasmid which contains this sequence and in which the above sequence is followed by the only Hind III cleavage site in the plasmid, into which site the gene to be expressed can be inserted, and to production plasmids for the expression of eukaryotic gene products in prokaryotes, especially for the preparation of leucocyte interferon.
Patent EP-0094708-B1 (EP)
IPC: G11B5/127
Filed: 1983-05-06
Granted: 1986-08-06
Abstract: A magnetic head (32) includes a magnet core (30) of ferrite and a layer of a bonding material (28) consisting of glass in the gap-forming area of the magnet core (38). In order to ensure that the ferrite is not attacked by the glass during the bonding process and that the temperature adjustment during the bonding process is not too critical, double layer diffusion barriers are provided between the layer of bonding material (28) and the core parts (10), (10'), respectively. Each barrier is formed by a layer of silicon nitride (26) on the side of the bonding layer (28) and a layer of silicon oxide (24) on the side of the core.
Patent EP-0091216-B1 (EP)
IPC: B65H19/10
Filed: 1983-03-11
Granted: 1986-07-09
Abstract: Web splicing apparatus for use in a reelstand having static positions for at least two reels comprising means for rotating a fresh reel on the reelstand, means for guiding a portion of the expiring web into a position adjacent to the periphery of the fresh reel, and means for moving the expiring web into contact with the periphery of the fresh reel to cause web splicing when the speeds of the fresh reel and the expiring web have been synchronized.