baber/WOPTO huggingface dataset:
Patent TW-202317577-A (TW)
Title: Novel compounds
Inventor: JOHANSSON MARTIN HANS
IPC: C07D487/04
Filed: 2022-06-30
Abstract: The invention provides a compound according to formula (I)
         or a tautomer thereof, wherein R
         1 , R
         2 , R
         3 , W
         1 , W
         2 , W
         3 , A, X and Y are as defined in the specification. The compounds are potent inhibitors of the serine/threonine kinase, TAK1.
        The present invention further provides: a pharmaceutical composition comprising a compound of formula (I) and at least one pharmaceutically acceptable excipient; a compound of formula (I) for use as a medicament (for example for the treatment or prophylaxis of a condition selected from cancer, inflammatory diseases, autoinflammatory diseases and autoimmune diseases); and a method of treating or preventing a disease or disorder comprising administering a pharmaceutically effective amount of a compound of formula (I) to a subject in need thereof.
Patent TW-202319756-A (TW)
Inventor: TODOROKI TAKESHI
IPC: G01R1/067
Filed: 2022-07-15
Abstract: A probe card includes an insulating layer, a first conductor that at least a portion extends along a surface of the insulating layer, and a second conductor that at least a portion penetrates through at least a portion of the insulating layer.
Patent TW-202317433-A (TW)
Title: Apparatus and method for filling syringes
Inventor: KIM JIN-HO
IPC: B65B3/00
Filed: 2022-07-22
Abstract: The present invention relates to an apparatus for filling a syringe, comprising: a pipeline for delivering a low viscous material discharged from a container; at least one downwardly directed injection port to connect with a syringe to be filled with the material delivered through the pipeline; a piston disposed within the syringe to be linearly movable in a longitudinal direction of the syringe and sealing the injected material between the injection port and the piston; and a syringe rod coupled to the syringe so as to press the piston into the syringe and to indicate a position of the piston, wherein each injection port has a needle valve to open and close the injection port.
Patent TW-202308402-A (TW)
Title: Vibration sensor
Inventor: Yuan yong-shuai
IPC: G01H11/06
Filed: 2022-07-27
Abstract: The embodiments of the present disclosure may disclose a vibration sensor, including: an acoustic transducer and a vibration element connected to the acoustic transducer. The vibration element may be configured to transmit external vibration signals to the acoustic transducer to generate electrical signals. The vibration element may include one or more groups of diaphragms and quality blocks. The quality blocks may be physically connected to the diaphragms. The vibration element may be configured to make the vibration sensor more sensitive than the acoustic transducer in one or more target frequency bands.
Patent TW-202315290-A (TW)
Title: Radiation tolerant voltage feedforward mode pulse-width modulator control
Inventor: LAM CUON
IPC: H02M3/07
Filed: 2022-07-29
Abstract: A pulse-width modulation circuit includes an oscillator stage. The oscillator stage includes a first voltage comparator having a first input terminal, a second input terminal and an output terminal. A first capacitor is coupled to the first input terminal of the first voltage comparator. A charging path for the first capacitor is coupled between the first capacitor and the output terminal of the first voltage comparator, the charging path having a first resistance. A discharging path for the first capacitor is coupled between the first capacitor and the output terminal of the first voltage comparator, the discharging path having a second resistance that is different from the first resistance. A duty cycle of a clock signal generated by the oscillator stage is determined based on a first RC time constant for charging the first capacitor and a second RC time constant for discharging the first capacitor.
Patent TW-202311292-A (TW)
Inventor: WEISS BERTRAM
IPC: A61P35/00
Filed: 2016-04-18
Abstract: 本發明是有關於一種雙特異性抗體構築體，其包含結合至目標細胞表面上之人類CDH3的第一人類結合域以及結合至T細胞表面上之人類CD3的第二結合域。此外，本發明提供一種編碼該抗體構築體的聚核苷酸、包含該聚核苷酸的載體以及經該聚核苷酸或載體轉形或轉染的宿主細胞。另外，本發明提供一種用於生產本發明抗體構築體的方法、一種該抗體構築體的醫學用途以及一種包含該抗體構築體的套組。
Patent TW-202313314-A (TW)
Title: Method for producing fiber-reinforced composite material
Inventor: SASAI YUYA
IPC: B29C70/48
Filed: 2022-08-09
Abstract: This method for producing a fiber-reinforced composite material comprises: a fiber dispersion step for providing a fiber-dispersed resin by kneading a resin 10a with a fiber 10b to disperse the fiber 10b in the resin 10a; and a molecular weight reduction step in which, while transporting the fiber-dispersed resin along an outer peripheral surface of a screw body 37 provided with a passage 88 in the interior, the fiber-dispersed resin is passed from an entrance 91 to the passage 88 to an outlet 92 of the passage 88 and in combination therewith a shear force is applied to the fiber-dispersed resin by restricting the transport of the fiber-dispersed resin with a barrier element 82 disposed between the inlet 91 of the passage 88 at the outer peripheral surface and the outlet 92.
Patent TW-202309428-A (TW)
Title: Duct module and burn-in chamber equipment including same
Inventor: NOH JONG-KI
IPC: F16L55/07
Filed: 2022-08-22
Abstract: A duct module includes a duct configured to provide a passage through which the fluid sucked from the outside of the chamber frame flows; and a discharge unit configured to guide the flow of the fluid so that the fluid sucked into the duct is discharged toward the electronic components arranged in the chamber frame, wherein the discharge unit is movably supported along the up and down direction with respect to the duct. Moreover, the duct includes a plurality of suction units for introducing the fluid sucked from the outside of the chamber frame to pass through the suction units; and a confluence unit communicated with the plurality of suction units so that the fluid introduced to pass through the plurality of suction units flows into the confluence unit, wherein the discharge unit includes a plurality of discharge parts and the fluid flowing through the confluence unit flows into the plurality of discharge parts.
Patent TW-202301911-A (TW)
Title: Methods and apparatuses for protecting a seal in a pressure vessel of a photolithography system
Inventor: BESSEMS DAVID
IPC: H05H1/42
Filed: 2018-09-19
Abstract: A vessel having a seal that is protected from the liquid material within the vessel by a volume of gas. The vessel has a partition that divides the vessel into two volume spaces such that the seal that is in gaseous communication with the first volume space is protected from the liquid material in the second volume space by a volume of gas in the first volume space.
Patent TW-202317733-A (TW)
Title: Polishing solution, polishing method, component manufacturing method, and semiconductor component manufacturing method
Inventor: ARATA Shogo
IPC: C09K3/14
Filed: 2022-08-31
Abstract: This polishing solution is for polishing a resin-containing polishing target member and contains an ether compound having a hydroxy group, and abrasive grains containing cerium oxide. This polishing method is for polishing a resin-containing polishing target member by using the polishing solution. This component manufacturing method is for obtaining a component by using the polishing target member polished by the polishing method. This semiconductor component manufacturing method is for obtaining a semiconductor component by using the polishing target member polished by the polishing method.
Patent TW-202321619-A (TW)
Title: Stove burner, and heating stove equipped with stove burner capable of stabilizing combustion by suppressing mutual flame interference of a lower first flame port and an upper second flame port
Inventor: SATO SHUN
IPC: F23D14/06
Filed: 2022-09-07
Abstract: A first forming member (21) on the lower side of a flame port forming member (20), which is recessed and provided with a plurality of radially-arranged first grooves (21e) along a circumferential direction, is arranged on an upper end of a first annular wall (21d) erected upward from an outer edge portion, such that an upward-protruded first protrusion part (21s) is formed between adjacent first grooves. On the other hand, a second forming member (22) on the upper side, which is recessed and provided with a plurality of radially-arranged second grooves (22b), is arranged on a second annular wall (22a) vertically arranged downward from the outer edge portion, such that a downward-protruded second protrusion part (22s) is formed between adjacent second grooves. In addition, the second forming member is separately placed on the first forming member in the circumferential direction in such a manner that the first groove and the second groove do not overlap, so that a first flame port (22Ua) is formed by the lower end of the second protrusion part and the first groove, and a second flame port (22Ub) is formed by the upper end of the first protrusion part and the second groove. At this time, the upper end of the first protrusion part is located above the lower end of the second protrusion part.
Patent TW-202327621-A (TW)
Title: New combination drug for treating coronavirus infections, pharmaceutical composition and use thereof
Inventor: LI CHIANG-QIANG
IPC: A61K31/625
Filed: 2022-09-15
Abstract: A new combination drug or a new pharmaceutical composition containing nitazoxanide and used with atovaquone and/or ribavirin, and the use thereof in preventing or treating coronavirus infections, in particular the use in preventing or treating infections caused by SARS-CoV-2 and mutants thereof.
Patent TW-202328449-A (TW)
Inventor: FARLEY JONATHAN EDWARD
IPC: C12N15/113
Filed: 2022-09-23
Abstract: The disclosure relates to double stranded ribonucleic acid interference (dsRNAi) agents and compositions targeting a microtubule-associated protein tau (MAPT) gene, as well as methods of inhibiting expression of a MAPT gene and methods of treating subjects having a MAPT-associated disease or disorder, e.g., Alzheimer's disease, frontotemporal dementia, progressive supranuclear palsy, or other tauopathies, using such dsRNAi agents and compositions.
Patent TW-202321308-A (TW)
Title: 使用抗ｔｉｇｉｔ抗體、抗ｃｄ３８抗體及ｐｄ—１軸結合拮抗劑治療血液癌症的方法
Inventor: MENG RAYMOND D
IPC: C07K16/28
Filed: 2022-09-30
Abstract: 本發明涉及方法及組成物，其用於治療患者的血液癌症（例如，骨髓瘤（例如，多發性骨髓瘤 (MM)，例如，復發性或難治性 MM）或淋巴瘤（例如，非何杰金氏淋巴瘤 (NHL)，例如，復發性或難治性彌漫型大 B 細胞淋巴瘤 (DLBCL) 或復發性或難治性濾泡性淋巴瘤 (FL)）），例如，藉由向該患者投予：包括具有 Ig 和 ITIM 域的抗 T 細胞免疫受體 (TIGIT) 拮抗劑抗體（例如，替瑞利尤單抗 (tiragolumab)）、PD-1 軸結合拮抗劑（例如，阿替利珠單抗 (atezolizumab)）以及抗 CD38 抗體（例如，達雷木單抗 (daratumumab)）的治療方案；包括抗 TIGIT 拮抗劑抗體（例如，替瑞利尤單抗）及抗 CD38 抗體（例如，達雷木單抗）的治療方案；或者，包括抗 TIGIT 拮抗劑抗體（例如，替瑞利尤單抗）及抗 CD20 抗體（例如，利妥昔單抗 (rituximab)）的治療方案。
Patent TW-202321473-A (TW)
Title: Rolled copper foil for secondary batteries, secondary battery negative electrode using same, and secondary battery
Inventor: OKABE FUMIYA
IPC: C22C9/02
Filed: 2022-10-19
Abstract: The present invention provides a rolled copper foil for secondary batteries, the rolled copper foil having good heat resistance, thereby maintaining high strength even after a heat treatment. The present invention provides a rolled copper foil for secondary batteries, the rolled copper foil containing 0.05% by weight to 0.15% by weight of Zr and 0.05% by weight or less of oxygen, with the balance being made up of Cu and unavoidable impurities, while having a tensile strength in a direction parallel to the rolling direction of 500 MPa or more after a heat treatment at 350 DEG C for 3 hours, and a change ratio of the tensile strength in the direction parallel to the rolling direction of 15% or less between before and after the heat treatment.
Patent TW-202326832-A (TW)
Title: Laser processing apparatus
Inventor: MAEDA ATSUSHI
IPC: H01L21/301
Filed: 2022-12-13
Abstract: A laser beam irradiation unit of a laser processing apparatus includes a laser oscillator that emits a laser beam, a characteristic conversion optical element that converts a characteristic of the laser beam emitted from the laser oscillator, a mirror and a collecting lens that are optical elements that guide the laser beam to a workpiece, a detecting unit that detects the water retention state of the characteristic conversion optical element, and a drying unit that dries the characteristic conversion optical element.
Patent TW-202330091-A (TW)
Inventor: NEOH BENG HUAT
IPC: B01F23/23
Filed: 2022-12-14
Abstract: 本發明係關於一種藉由向連續流動的高純水中加入氣體來以該連續的高純水流連續生產超純水的方法。在兩個連續的步驟中加入氣體，以及在每個步驟之後測量水-氣溶液的電導率和/或電阻，以便調整所引入的氣體量以及達到目標值。本發明還關於一種藉由該方法所生產的連續的超純水流的用途。此外，本發明還關於一種用於連續生產超純水和用於實施該方法的設備（12）。還描述了一種用於切割部件的裝置（20）。
Patent TW-202334183-A (TW)
Title: 免疫球蛋白降解酶ｌｄｅＥ的突變體的用途
Inventor: Liu yan-jun
IPC: C07K14/315
Filed: 2022-12-22
Abstract: 本發明涉及一種免疫球蛋白降解酶IdeE的突變體、包含所述突變體的蛋白、組合物和套組在製備用於降低受試者中的IgG水準的藥物中的用途。其中所述突變體在SEQ ID NO: 2所示的胺基酸序列的位置8、10、24、59、97和280中的一位或者多位具有胺基酸取代、N端截短和/或C端截短，所述的突變體具備免疫球蛋白降解酶IdeE的功能，並具有高於或等於野生型IdeE的活性和熱穩定性。
Patent TW-202331444-A (TW)
Title: Voltage regulator
Inventor: KUNG NIEN-HUI
IPC: G05F1/10
Filed: 2023-01-16
Abstract: A voltage regulator with dynamic voltage and frequency tracking is provided. The voltage regulator has power switches converting an input voltage into an output voltage, a loop controller, a voltage comparator, and a target voltage generator. The loop controller is coupled to the power switches to control the power switches to perform voltage regulation. The voltage comparator compares the output voltage to the target voltage to generate a first control signal to control the loop controller. The target voltage generator generates the target voltage for the voltage comparator based on the frequency difference between the target frequency and the critical-path-related frequency, wherein the critical-path-related frequency depends on the output voltage. The power efficiency and response time are improved.
Patent TW-202337065-A (TW)
Title: Longitudinal constraints for energy storage devices
Inventor: BUSACCA ROBERT S
IPC: H01M10/0525
Filed: 2016-05-13
Abstract: A energy storage device for cycling between a charged state and a discharged state, the energy storage device including an enclosure, an electrode assembly and a non-aqueous liquid electrolyte within the enclosure, and a constraint that maintains a pressure on the electrode assembly as the energy storage device is cycled between the charged and the discharged states.
Patent TW-202330769-A (TW)
Title: Curative
Inventor: AMSTUTZ AARON KENNETH
IPC: C08K5/092
Filed: 2019-04-19
Abstract: A curative for epoxidized plant-based oils and epoxidized natural rubber is created from the reaction between a naturally occurring polyfunctional acid and an epoxidized plant-based oil is disclosed. The curative may be used to produce porosity-free castable resins and vulcanize rubber formulations based on epoxidized natural rubber. Materials made from disclosed materials may be advantageously used as leather substitutes.
Patent UA-51871-A (UA)
Title: Imitation game
Inventor: SHATAGINA OLEKSANDRA YAKIVNA
Filed: 2000-05-17
Abstract: Imitation game is used in gaming technique of teaching. Imitation game comprises game area and game figures. The game area is arranged as three normal to each other planes made of magnetic material. Imitation figures are made of wire, with possibility of bending those, and the bases of those have magnets. Game area may be provided with points, made at the inner bibs of the planes of those. Imitation figures may have connected to those arrows-pointers. Technical result consists in broadening of functional possibilities of game.
Patent UA-38107-A (UA)
Title: Photometer
Filed: 2000-05-30
Abstract: The invention relates to technology of control of quality of half-finished products and products of processing and food enterprises. The invention can be used at production of any direction where it is needed to control optical coefficient of passing liquids in visible region of optical spectrum. In the device for measurement of optical transparence of liquids one uses controlled high-frequency generator varicap matrix of frequency-master circuit of which is connected to output of photo-receiver. Output of controlled high-frequency generator is connected to first input of mixer to the second input of mixer output of standard generator is connected. To the output of the mixer through frequency detector secondary device is connected.
Patent UA-55763-A (UA)
Title: Method for optimization in treatment of bronchial asthma at hospital stage
Inventor: Malenkii Vasyl Pavlovych
Filed: 2002-06-07
Abstract: The method for optimization in the treatment of the bronchial asthma at the hospital stage provides for administering the broncholytic and mucolytic drugs in the complex with glucocorticosteroids. First Berodual in saline solution is administered employing the nebulizer, then Ambrobene is given in the same mode followed by Budesonid inhaled with the aid of the aerosol metered dose inhaler.
Patent DO-P2001000301-A (DO)
Title: Agonistas beta-3-adreno-receptores de derivados de aminometil cromano di-sustituido
Inventor: CORPORATION BAYER
Filed: 2001-12-10
Abstract: ESTA INVENCION SE REFIERE A NUEVOS DERIVADOS AMINOMETILO CROMANO DI-SUSTITUIDOS QUE SON UTILES EN EL TRATAMIENTO DE LAS CONDICIONES INTERMEDIADAS POR EL RECEPTOR BETA-3
Patent DO-P2003000598-A (DO)
Title: Terapias de combinacion para tratar celulas deficientes en metiltioadenosina-fosforilasa
Inventor: SKALITZKY DONALD JAMES
Filed: 2003-03-04
Abstract: La presente invencion se refiere a terapias de combinacion para tratar trastornos de proliferacion celular asociados con celulas deficientes en metiltioadenosina fosforilasa ("MTAP") en un animal mamifero. Las terapias de combinacion destruyen selectivamente las celulas MTAP-deficientes por administracion de un inhibidor de la sintesis de inosinato de novo y administrando un agente anti-toxico, en donde los inhibidores de la sintesis de inosinato de novo son inhibidores de glicinamidaribonucleotido-formiltransferasa ("GARFT") y/o aminoinidazolcarboximida ribonucleotido-formiltransferasa ("AICARFT"), y el agente anti-toxico es un sustrato de MTAP (p.ej., metiltioadenosina o "MTA"), un precursor de MTA, un analogo de un precursor de MTA o un profarmaco de un sustrato de MTAP.
Patent DO-P2014000137-A (DO)
Title: Nuevo uso terapéutico de antagonistas del receptor p75
Inventor: AVALLONE ROBERTA
IPC: A61K31/497
Filed: 2014-06-17
Abstract: La presente invención proporciona el uso de un antagonista del receptor p75 o sus sales farmacéuticamente aceptables para la preparación de un medicamento para uso en el tratamiento y/o prevención de vejiga sobreactiva.
Patent GB-189706218-A (GB)
Title: Improvements in Lenses.
Inventor: BARKER EDWARD WILLIAMS
Filed: 1897-03-09
Granted: 1897-05-01
Abstract: 6218. Barker, E. W. March 9. central lens a, which may be formed in segments, and annular rings b, d, e, f, g built around it, also in segments. The parts, although shown as simple, are each of them compound, and are held by a suitable framework (not shown) of radial and circular bars with adjustable clamps, all interstices being filled in with opaque cement. All the elements have the same principal focus, and the straight lines bounding any section are as indicated in Fig. 1.
Patent GB-189706567-A (GB)
Title: Pneumatic Tide Gauge.
Inventor: MENSING ADOLF
Filed: 1897-03-12
Granted: 1898-03-12
Abstract: 6567. Mensing, A. March 12. Tide gauges.-The apparatus is shown diagrammatically with the U tubes a, c, and b in two positions, but in practice the parts are compactly disposed within a cylinder and supported, with a thermograph, upon a gimballed table. The cylinder rests upon the sea-bottom on a stand, and can be drawn up when required by chains K in the containing-vessel, which is charged with air compressed approximately to the pressure at the bottom of the sea and is then lowered with the cock k closed. In this way, when the cock is opened very little water passes in or out. L is an air chamber having a differential recording pressure gauge and connected at first by the U tube a, c with the air in K through hygroscopic tubes V. A branch tube b has a mercury seal x and terminates in a funnel below a tilting vessel H filled with mercury. So long as L and K are thus freely connected the differential gauge shows zero. After a time, however, clockwork tilts the vessel H, discharging mercury into the tubes a, b, c, whereupon any variation of pressure in K due to the tide causes a displacement of the mercury in the tubes a, b, c and does not appreciably affect the pressure in L. The gauge M therefore records the variations.
Patent GB-189717806-A (GB)
Title: Improvements in Advertising or Signalling.
Inventor: RALEIGH CHARLES
Filed: 1897-07-29
Granted: 1898-07-29
Abstract: 17,806. Raleigh, C. July 29. Signals, electriclamp.-In advertising or signalling with the aid of letters or other signs delineated by means of electric lamps &c. the lamps are arranged in such a manner that the greatest number of letters or signs may be formed in the space occupied by one letter with a minimum number of lamps. Fig. 2 shows the manner in which fifty-one lamps may be arranged for producing at will any one of the letters of the alphabet, the greater number of the lamps being arranged symmetrically with regard to the horizontal or vertical axis of the figure. The lamps corresponding to any particular letter are illuminated by the use of a switchboard, Fig. 5, marked with the letters of the alphabet, and having a radial arm B which, when moved into the position corresponding to the letter desired, engages with a series of contacts arranged radially on the board and corresponding to the lamps required to form the letter. The arm B may be operated by spur or other gearing from a suitable transmitting- instrument, such as a board having letters round its circumference and provided with a suitable pointer, or, in the case of set advertisements, it may be rotated continuously by means of a motor. In Figs. 4<a> and 4<b> an alphabetical telegraph is electrically connected with the switch. In this case a radial arm W is provided for each radial set of contacts, and is normally kept out of engagement therewith by a spring. When a signal is transmitted, the arm Y<1> of the receiving-instrument moves into the position corresponding to the signal, and completes the circuit of a corresponding arm W<1>, which is forced into engagement with its contacts by means of a solenoid T<1>. To prevent those signals being illuminated corresponding to the contacts over which the arm Y must pass to reach the required position for the signal, the current for adjusting the arm Y' is of insufficient strength to bring into action a relay circuit in which the lamps are placed. This circuit is closed after the signal has been adjusted by means of an auxiliary switch. Modifications are described.
Patent GB-189722535-A (GB)
Title: Improvements in and relating to Supporting Devices and Driving Mechanism for Velocipedes.
Inventor: MACKLEY GEORGE THOMAS
Filed: 1897-10-01
Granted: 1898-08-20
Abstract: 22,535. Mackley, G. T. Oct. 1. S a f e t y-wheels ; driving-mechanism. -Bicycles are fitted with T-shaped frames A, A' carrying rollers C, to enable riders to mount and dismount when the machines are at rest. The T-shaped frame is formed as a part of the bicycle frame or is secured to it by clamps a. The wheels or rollers C are carried by forks B, the stems of which are mounted in spring sockets a<3> to allow the wheels to rise and fall. Pins b<1> fixed to the fork stems pass through shaped slots in the spring sockets a<3> and allow the wheels to turn slightly when the bicycle is rounding a curve. Curved plate springs E keep the wheels running normally in a straight line. Each of the wheels 0 may be inclined so as to be perpendicular to the ground when touching it. The forks B are slotted to enable the wheels C to be raised or lowered. The Provisional Specification describes a driving- mechanism consisting of rocking foot-levers or plates connected with cranks or clutches on the driving-wheel or axle.