baber/WOPTO huggingface dataset:
Patent DE-69623784-T2 (DE)
Inventor: PHILLIPS G
IPC: A61P25/20
Filed: 1996-06-06
Granted: 2003-05-15
Abstract: The present invention is directed to 1H-4(5)-substituted imidazole derivates of formula (I), wherein A is (a); (b); or (c) where R1 is lower alkyl or lower alkoxy; R2, R3, R4, R5, R7 and R8 are each independently hydrogen or lower alkyl; R6 is hydrogen, lower alkyl or lower alkoxy and R5 and R6 can be joined to form a 4, 5 or 6 membered ring. The compounds of formula (I) have H3 histamine receptor agonist activity. The pharmaceutically acceptable salts, and individual stereoisomers of compounds of formula (I) above, as well as mixtures thereof, are also contemplated as falling within the scope of the present invention. The present invention also provides pharmaceutical compositions comprising a pharmaceutically acceptable carrier in combination with an effective amount of a compound of formula (I). The present invention also provides a method of treating conditions in which activation of histamine H3 receptors may be of therapeutic importance such as allergy, inflammation, cardio or cerebrovascular disease (i.e., hyper or hypotension, ischemia, stroke, migraine), gastrointestinal disorders (acid secretion, motility) and CNS disorders involving psychiatric disorders (i.e., including anxiety, manic/depressive disorder, schizophrenia, obsessive-compulsive disorders, etc.).
Patent DE-69631668-T2 (DE)
Inventor: DUTTON JANE
IPC: C08J5/18
Filed: 1996-09-09
Granted: 2005-02-17
Abstract: Poly(lactones) are provided. The poly(lactones) are obtained by polymerization of a lactone with an initiator system comprising at least one polyfunctional initiator. The poly(lactones) have a shear viscosity at some temperature in the range of from 35 to 45° C. above the melting temperature of the poly(lactone) of at least 6 kPas at 0.1 s-1 shear rate and no greater than 3.5 kPas at 100 s-1 shear rate, and a shear viscosity activation energy of greater than 40 kJ/mol. Preferably, the poly(lactone) is poly(caprolactone).
Patent DE-69632926-T2 (DE)
Inventor: GETMAN DANIEL P
IPC: C07D263/56
Filed: 1996-03-07
Granted: 2005-07-21
Abstract: Selected sulfonylalkanoylamino hydroxyethylamine sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease. The present invention relates to such retroviral protease inhibitors and, more particularly, relates to selected novel compounds, composition and method for inhibiting retroviral proteases, such as human immunodeficiency virus (HIV) protease, prophylactically preventing retroviral infection or the spread of a retrovirus, and treatment of a retroviral infection.
Patent DE-69703943-T2 (DE)
Inventor: CHRISTIANSEN NIELS
IPC: H01M8/00
Filed: 1997-02-04
Granted: 2001-05-23
Abstract: A lanthanide oxide ceramic material having the general formula: LaaLnbM'cM''dO3- delta , wherein   Ln   is a combination of Ce, Pr and Nd; M'   is at least one alkaline earth metal; M''   is at least one metal selected from the group consisting of Co, Fe, Ni, Zn, Cu, Mn, Al, V, Ir, Mo, W, Pd, Pt, Mg, Ru, Rh, Cr and Zr; and  0 ≤ a ≤ 1; 0.01< b ≤ 1;  0 ≤ c ≤ 0.6; 0 ≤ d ≤ 1; and -1 <  delta  < +1 o
Patent DE-69704101-T2 (DE)
Inventor: BOOT ADRIAAN JOHAN
IPC: H04B10/572
Filed: 1997-11-20
Granted: 2001-08-30
Abstract: Optical stabilisation system having a signal source (1) connected to a transmission line (2) and a noise source (3). The signal source (1) comprises a laser having a number of laser modes within a first wavelength band for generating an optical transmission signal (S). The noise source generates a narrow-band noise signal which is inserted into the transmission line via coupling means (5) and is injected into the laser of the signal source (1). The noise signal forces the laser to operate in a laser mode within the noise band. Via a power distributor (11), a portion of the noise signal can also be injected into a laser of a further signal source (9) for stabilisation in a laser mode within the same noise band. Any signals outside the noise band are removed from the transmission signal by a narrow-band filter (8). The stabilisation system is applied in passive optical networks for groupwise wavelength assignment to network terminals. <IMAGE>
Patent DE-69706188-T2 (DE)
Inventor: MERCER W
IPC: C08L101/00
Filed: 1997-10-28
Granted: 2002-05-02
Abstract: A highly thermally conductive but yet highly conformable composition is made from gel filled with alumina. The use of  alpha -alumina in which at least 10 weight % of the  alpha -alumina particles have a particle size of at least 74  mu m makes possible the high filler levels needed to attain high thermal conductivity, without causing the decrease in elongation and softness normally associated with high filler levels. Further improvements are observed if the  alpha -alumina and the gel (or precursor thereof) are mixed with a specific energy input of at least 10 Joule/g. The input of such specific energy has the effect making the resulting composition more conformable than it otherwise would be. The composition may be internally supported by a flexible matrix such as a fabric or open-celled foam.
Patent DE-69707925-T2 (DE)
Inventor: DAVARZAN HAMID
IPC: C12Q1/04
Filed: 1997-03-05
Granted: 2002-06-20
Abstract: The present invention concerns a device for testing resistance in microorganisms present in e.g. urine. The device comprises a cylindric container (1) fitted with a spout (3) of a considerably lesser diameter and a plunger (2) making a tight seal against the wall of the container (1), having a radially extending gasket (6) and being partly coated with nutrients for growing microorganisms, the coated part being arranged at the front part of the plunger (2) and comprising at least three angularly arranged test laminate (4A, 4B, 4C), at least one of which is coated with nutrients and antibiotics of different kinds and concentrations. The lower end surface (Ä) of the container (1) is conically shaped with a peak turning into the spout (3) preventing urine from remaining on the surface (Ä) when the container (1) is emptied after the laminae (4A, 4B, 4C) have been wetted with urine and before the device is incubated.
Patent DE-69717338-T2 (DE)
Inventor: BRIERE PAUL
IPC: F42B5/15
Filed: 1997-03-10
Granted: 2003-09-18
Abstract: A decoy flare comprises: (i) a tubular shell (1) with a cover (3) and a movable closure (7); (ii) front and rear rupturing discs (2,4) sealing in a pyrophoric liquid (17); (iii) a gas generating energetic material disc (11) adjacent to the rear disc for generating a force which ruptures one disc directly and the other through a piston (18); and (iv) an initiating device to activate the gas generator (11) and eject the pyrophoric liquid.
Patent DE-69725014-T2 (DE)
Inventor: LIU CHIN
IPC: C07C213/04
Filed: 1997-12-19
Granted: 2004-06-09
Abstract: In a method of preparing an aminoepoxide wherein a protected aminoaldehyde is reacted with a halomethyl organometallic reagent in an appropriate solvent at a temperature above -80 DEG  C., wherein said halomethyl organometallic reagent is formed by reaction between an organometallic reagent and a dihalomethane, the improvement comprising flowing said protected aminoaldehyde into a mixing zone maintained at a temperature below 0 DEG  C., also flowing said halomethyl organometallic reagent in said mixing zone for contacting in said mixing zone with said protected aminoaldehyde and also withdrawing from said mixing zone reaction products of said protected aminoaldehyde and said halomethyl organometallic reagent.
Patent DE-69731060-T2 (DE)
Inventor: SCHADE III
IPC: G05B11/42
Filed: 1997-11-26
Granted: 2005-11-17
Abstract: A feedback control system which includes a disturbance estimator and controller which takes account of and corrects for non-linear disturbances. A simple state model representative of the controlled plant is provided. A plant controller responds to a command signal and a process feedback signal for producing a controller output. The controller output drives both the plant and the state model. A sensed signal representing a state of the plant is compared with a corresponding output state of the model to produce an error signal which is representative of disturbances applied to the system. The disturbance estimator and controller responds to the error signal to produce a disturbance control output which is adapted to compensate for the non-linear disturbance. In a preferred embodiment the plant is an actuator and the non-linear disturbances are friction related. The disturbance control output in the preferred embodiment has an initial constant magnitude summed with an increasing ramp, and the disturbance estimator senses polarity reversals in the error signal to reverse the polarity of at least the constant component of the disturbance output. <IMAGE>
Patent DE-69806582-T2 (DE)
Inventor: JENSEN STEEN
IPC: A61K9/00
Filed: 1998-03-20
Granted: 2003-02-13
Abstract: A process for the preparation of a therapeutic powder formulation comprising particles composed of insulin or an analogue or derivative thereof and an enhancer which enhances the absorption of insulin in the lower respiratory tract is provided. The obtainable powder formulation of insulin and enhancer has a better stability profile than powders of essentially the same composition prepared by spray drying, freeze-drying, vacuum drying and open drying.
Patent DE-69820466-T2 (DE)
Inventor: BOLLING F
IPC: A61M60/873
Filed: 1998-10-09
Granted: 2004-10-28
Abstract: An extracardiac pumping system for supplementing the circulation of blood through a patient without any component thereof being connected to the patient's heart, and method of using same. The extracardiac system comprises a pump implanted subcutaneously at or about the patient's groin in a minimally-invasive procedure, wherein the pump is powered by a battery, and means for charging the battery extracorporeally, wherein the pump draws blood through an inflow conduit fluidly coupled to the patient's femoral artery via a subcutaneous anastomosis connection, and discharges blood through an outflow conduit fluidly coupled to a peripheral artery that stems from the patient's aortic arch via a subcutaneous anastomosis connection. The pump may be operated continuously or in a pulsatile fashion, synchronous with the patient's heart, thereby potentially reducing the pumping load on the heart.
Patent DE-69821196-T2 (DE)
Inventor: DEAN JEFFREY A
IPC: G06F12/08
Filed: 1998-11-25
Granted: 2004-09-02
Abstract: An apparatus for sampling states of a computer system having a hierarchical memory arranged at a plurality of levels, the hierarchical memory storing data at addresses. The apparatus includes a selector for selecting memory transactions based on first state and transaction information. The memory transactions are to be processed by the hierarchical memory. A trigger activates the selector based on second state and transaction information. A sampler stores states of the computer system that are identified with the selected instructions while processing the selected memory transactions in the hierarchical memory. <IMAGE>
Patent DE-69822501-T2 (DE)
Inventor: LAKER PAUL
IPC: B65D5/06
Filed: 1998-10-29
Granted: 2005-02-03
Abstract: A boxed end container is shown having one end closed by a transverse ridge seal and carrying a pull tab. The pull tab allows a separating force to be applied to the ridge seal of the sealed container to separate at least part of the ridge seal and thus open the container and allow discharge of its contents. The pull tab is a generally planar member having an axially extending shank member with a proximal end portion which can be gripped and pulled by a user and a distal end portion having foot members extending transversely to each side of thereof. The shank and foot members are substantially co-planar with one another. The pull tab is secured by the foot members externally to a wall of the container at or adjacent to the ridge seal of the container.
Patent DE-69828811-T2 (DE)
Inventor: ELLENBERGER PETER
IPC: C09K17/18
Filed: 1998-09-15
Granted: 2005-12-22
Abstract: A method of boring a tunnel through a stratum utilizing a shield tunneling apparatus, the process comprising the injection into the stratum at the cutting face of an aqueous material comprising (a) from 0.005-0.05% by weight of a polyethylene oxide of weight-average molecular weight from 2,000,000 to 8,000,000 (b) from 0.05-0.5% by weight of a sulphate-containing anionic surfactant. The method is effective even in difficult soils.
Patent DE-69834311-T2 (DE)
Inventor: SCHWAB MANFRED
IPC: B21J15/04
Filed: 1998-12-09
Granted: 2007-01-18
Abstract: In a device for clamping a stem to the traction mandrel of a riveting tool, the traction mandrel has a traction sleeve (11) loosely fitted in the enclosing sleeve (12) and mutually secured with the enclosing sleeve against axial shifting and turning. Between the enclosing sleeve and the peripheral recess in the traction sleeve (11) there is a compression spring (10). The traction sleeve (11) has an inner thread, onto which is screwed the stem (1), whose collar has at least one flattened plane on its outer circumference corresponding to an inner peripheral surface of the adjacent part of the enclosing sleeve (12). The device is fitted together with the traction mandrel (13) in the nozzle (5) of the riveting tool, wherein the nozzle has a passage opening in the area of the enclosing sleeve (12). Without the use of a tightening instrument as for example a key, it is possible to change easily and very quickly the mandrels for rivets in the riveting tool. <IMAGE>
Patent DE-69903550-T2 (DE)
Inventor: DE ALMEIDA RODRIGUES CARLOS
IPC: B65G51/03
Filed: 1999-07-05
Granted: 2003-06-26
Abstract: The air conveyor comprises a guide rail (3) on which the articles (1) are to be suspended, and along which the articles are to be transported in a given direction of transport. The conveyor system provides a pneumatic means to move the articles in the direction of transport and further includes additional pneumatic means (10) that are designed to generate, when operated, a plurality of reverse air jets orientated onto the articles in a direction opposite that of their direction of transport. The user of the reverse jets makes it possible, in particular, to free without manual intervention articles accidentally immobilised in the course of transport, or, to slow down, immobilise or impart a rhythm to the articles as they are transported.
Patent DE-69907127-T2 (DE)
Inventor: ROESGEN ALAIN EMILE FRANCOIS
IPC: B60C3/00
Filed: 1999-01-20
Granted: 2004-02-12
Abstract: A run-flat radial ply pneumatic tire (20) having a carcass (30) reinforced with elastomeric crescent shaped sidewall fillers (42) and two bead cores (41,41') is disclosed. A cord reinforced hoop (21) extends radially inwardly of one or more belt plies (50,51) about halfway between the lateral tread edges (14,16). A rubber insert (22) is interposed between the radially inner belt (50) and the hoop (21). The tire (20) made according to the invention provides excellent run-flat capability and exhibits improved ride over conventional run-flat tires. <IMAGE>
Patent DE-69910777-T2 (DE)
Inventor: FREEMAN NEVILLE JOHN
IPC: G01N21/77
Filed: 1999-05-27
Granted: 2004-07-08
Abstract: A device for housing a planar optical component such as a chemical sensor comprising a holder for mounting a planar optical component, a housing adapted to receive internally said holder along a longitudinal axis, and guiding means for correlating the position of said planar optical component and of a source of electromagnetic radiation when said holder is located within said housing.
Patent DE-69915013-T2 (DE)
Inventor: MAZZOLI ERNESTO
IPC: A01K1/015
Filed: 1999-10-29
Granted: 2004-10-21
Abstract: A method of animal husbandry and rearing which provides for the use of a bedding constituted by a composition including at least 40% by weight of coconut fibre of the type known as "cocopeat". The method of rearing animals forming the subject of this invention as well as providing good welfare conditions is utilised to reduce or eliminate the development of mycotoxins and improve the yield and quality of the meat.
Patent DE-69920802-T2 (DE)
Inventor: KOIVUROVA MARKKU
IPC: F16C11/06
Filed: 1999-05-21
Granted: 2006-03-02
Abstract: A spring articulation structure particularly for play, fitness training and sports instruments, said structure comprising a core element (1) supported in between two rubber rings (2) and provided with a shaft element (5) fitted in said core element; a shell compactly surrounding the core element and the rubber rings and attached to a bottom plate (9), the top part (3') of said shell being in the middle provided with a aperture (8) with a downwardly narrowing conical surface (7) for the shaft element (5); and a cylindrical element (4) resting on top of the top part (3') of the shell and surrounding the shaft element (5). <IMAGE>
Patent DE-69929459-T2 (DE)
Inventor: TALISH J
IPC: A61F2/36
Filed: 1999-11-12
Granted: 2006-08-24
Abstract: A bone prosthesis (10) includes a first portion for engaging a first bone segment and at least one channel (34) disposed within the first portion for propagating acoustic energy through the channel to the first bone segment. The channel includes an interior reflective surface which defines a resonating chamber disposed through the first portion which propagates acoustic energy to the first bone segment to stimulate bony ingrowth. The present disclosure also relates to a method for measuring the stability of an implanted prosthesis which includes the steps of: a) providing a source (11) having a probe for sending and receiving signals and a comparator for comparing and analyzing prior signal data with newer signal data; b) placing the probe (15) adjacent the prosthesis; c) transmitting an initial signal through the probe to the prosthesis; d) receiving a return signal from the probe after the signal propagates and returns through the prosthesis; e) storing the return signal data; f) repeating steps (a) through (e); and g) comparing and analyzing stored return signal data to determine implant stablilization.
Patent DE-69933014-T2 (DE)
Inventor: RUTH M
IPC: F16D41/12
Filed: 1999-02-23
Granted: 2007-02-15
Abstract: A hub for a torque-transmitting member comprising a planar clutch. The clutch includes a pocket plate and a notch plate located within the hub. One plate is integrated within the hub, such as by casting or molding, to form an integral assembly, the other plate being splined or otherwise secured to a shaft. The pocket plate has strut pockets disposed about the axis of the hub. The notch plate has recesses at angularly spaced positions about the axis. Struts pivotally anchored in the strut pockets engage the notch plate recesses to effect one-way torque transfer between the plates.
Patent DE-69937893-T2 (DE)
Inventor: SEKIYA KUNIO
IPC: D21F5/02
Filed: 1999-09-14
Granted: 2008-04-17
Abstract: The invention provides a method of preventing contamination of a dryer of a paper machine so that a predetermined anti-fouling effect can always be ensured over a long term while maintaining satisfactory drying efficiency. With the method of preventing contamination of the surface of a drum dryer used in a paper machine, according to the invention, a predetermined amount of a surface forming agent P is continuously supplied to the surface of the drum dryer D1 in rotation, facing a paper strip W, while the paper strip W is being fed by the paper machine in operation. <IMAGE>
Patent HU-E028143-T2 (HU)
Title: Novel bacillus thuringiensis crystal polypeptides, polynucleotides, and compositions thereof
Inventor: BERMUDEZ ERICKA
IPC: C12N5/04
Filed: 2005-02-25
Abstract: The present invention provides insecticidal polypeptides related to  Bacillus  Cry2 polypeptides. Nucleic acids encoding the polypeptides of the invention are also provided. Methods for using the polypeptides and nucleic acids of the invention to enhance resistance of plants to insect predation are encompassed.
Patent HU-E030591-T2 (HU)
Title: Anti-Abeta antibodies and their use
Inventor: BARDROFF MICHAEL
IPC: G01N33/68
Filed: 2003-02-20
Abstract: The present invention relates to antibody molecules capable of specifically recognizing two regions of the β-A4 peptide, wherein the first region comprises the amino acid sequence AEFRHDSGY as shown in SEQ ID NO: 1 or a fragment thereof and wherein the second region comprises the amino acid sequence VHHQKLVFFAEDVG as shown in SEQ ID NO: 2 or a fragment thereof. Furthermore, nucleic acid molecules encoding the inventive antibody molecules and vectors and hosts comprising said nucleic acid molecules are disclosed. In addition, the present invention provides for compositions, preferably pharmaceutical or diagnostic compositions, comprising the compounds of the invention as well as for specific uses of the antibody molecules, nucleic acid molecules, vectors or hosts of the invention.
Patent TR-200003502-T2 (TR)
Title: Bir Piperidin Maddesi P Antagonistini İçeren Mikroemülsiyon Prekonsantratları
Inventor: LANG STEFFEN
IPC: A61K9/22
Filed: 1999-05-26
Abstract: Bir piperidin, mesela, 1-asil-piperidin madde P antagonistini içeren mikroemülsiyon ve  söz konusu mikroemülsiyonun, merkezi sinir sistemi rahatsizliklari, mesela, depresyon ve sosyal fobi ve solunum hastaliklari, mesela, astim ve kronik bronsitin tedavisinde kullanimi.
Patent TR-200100368-T2 (TR)
Title: Sert hedefler için yangın roketi.
Inventor: JONES JOHN WILLIS
IPC: F42B12/44
Filed: 1999-06-16
Abstract: Bu bulus sert hedefler için bir yangin çikarici rokete yönelmistir. Bu roket yangin çikarici malzemeyle doldurulmus ve bir kapakla kapatilmis bir arka deligi haiz bir delici muhafaza içerir. Roket bir hedefe çarptiginda ve içeri girdiginde bir fünye yangin çikarici malzemeyi tutusturur. Yanmakta olan yangin çikarici malzemenden çikan sicak gazlar muhafaza içinde basinci arttirir; böylece fünyenin ateslenmesini izleyen mili-saniyeler içinde muhafaza içindeki basinç güçlü bir darbesiyle kapagi arka delikten firlatir; basinç darbesi yangin çikarici malzemenin yanmakta olan parçalarini hedef içine atar. Roket kimyasallar, radyoaktif malzemeler ve elektrik/elektronik cihazlar gibi hedef içine firlatilabilecek ek yükler tasiyabilir.
Patent DE-602004000433-T2 (DE)
Inventor: FLINT LUDGER
IPC: H04W4/029
Filed: 2004-07-19
Granted: 2006-08-31
Abstract: A method of operating a portable communication device (101), wherein: in response to receiving a paging request (PREQ) from a cellular network (100) over a first communication channel (GSM) the portable communication device (101) i) discards the paging request (PREQ), or ii) delays transmitting a paging response (PRES), if the portable communication device (101) has an established GPRS PDP context on a second communication channel (GPRS) requiring an action (K1) that can be performed within a predefined time.
Patent DE-602004007093-T2 (DE)
Inventor: MELANDER PER
IPC: H03M7/30
Filed: 2004-12-06
Granted: 2008-02-21
Abstract: In a method of processing data to be transferred in an SMS message, each group of the data that comprises six bits or less is converted into one of sixty-four SMS characters in accordance with a predetermined conversion table, and each group of the data that comprises more than six bits is divided into separate 6-bit groups and each separate 6-bit group is converted into an SMS character in accordance with the predetermined conversion table. To process data transferred as SMS characters, the SMS characters are converted into 6-bit groups in accordance with the predetermined conversion table, and the bits of the 6-bit groups are regrouped into groups corresponding to the original structure of the transferred data. <IMAGE>
Patent DE-602005005917-T2 (DE)
Inventor: LAURENT LUDIVINE
IPC: A61Q5/06
Filed: 2005-10-21
Granted: 2009-05-20
Abstract: Cosmetic composition (A), comprises sulfonic polyester (I) (dispersible in water) and polyurethane (II) (having a number average molecular weight of 400000-5000000 g/mol) in a medium.