baber/WOPTO huggingface dataset:
Patent NZ-513893-A (NZ)
Title: Pyrimidine compounds
Inventor: BREAULT GLORIA ANNE
IPC: C07D239/48
Filed: 2000-03-02
Abstract: A pyrimidine derivative of formula (I) or (I'): wherein: R<x >is a substituent as defined within; Q1 is optionally substituted phenyl, and Q1 bears a substituent of formula (Ia) wherein: X, Y<1>, Y<2>, Z, n, and m are as defined within; -NQ2 is an optionally substituted heterocyclic moiety containing one hydrogen heteroatom and optionally containing a further heteroatom; or a pharmaceutically acceptable salt in vivo hydrolysable ester thereof; are useful as anti-cancer agents. Processes for their manufacture and pharmaceutical compositions containing them are described.
Patent NZ-516269-A (NZ)
Title: Pharmaceutical compositions comprising cyclosporine
Inventor: SHERMAN BERNARD CHARLES
IPC: A61K38/13
Filed: 2001-12-20
Abstract: A pharmaceutical composition comprising cyclosporine dissolved in a solvent-surfactant system, which disperses in water at 37°C to form an emulsion in which more than 50 percent of the cyclosporine is in droplets of diameter less than 0.45 microns, and wherein the solvent-surfactant system comprises: a hydrophilic surfactant, and a lipophilic surfactant, and optionally further comprises a hydrophilic solvent, with the further provisos that: i)  the amount of cyclosporine by weight is greater than 10 percent of the total of cyclosporine, hydrophilic surfactant, lipophilic surfactant and hydrophilic solvent; ii)  the composition is free of lipophilic solvent or comprises less than 1 part lipophilic solvent per part cyclosporine by weight; iii)  if the composition comprises ethanol, the amount of cyclosporine by weight is greater than 15 percent of the total of cyclosporine, hydrophilic surfactant, lipophilic surfactant and hydrophilic solvent; iv)  if the composition comprises glycofurol, the amount of glycofurol is less than 1 part per part cyclosporine by weight, or alternatively the amount of cyclosporine by weight is greater than 19.25 percent of the total of cyclosporine, hydrophilic surfactant, lipophilic surfactant and hydrophilic solvent; v)  if the composition comprises proplylene glycol and does not comprise ethanol, the amount of propylene glycol is less than 1.2 parts per part cyclosporine by weight, or alternatively the amount of lipophilic surfactant exceeds 0.55 parts per part cyclosporine by weight. Addition to 516269
Patent NZ-519103-A (NZ)
Title: Gutter protector and guttering incorporating same
Inventor: WEST DAVID LAURISTON
IPC: E04D13/076
Filed: 2000-03-29
Abstract: Gutter protector (10) comprises a profiled sheet (28) that extends over a gutter invert (24A) above a gutter floor (24) for collecting water and debris that would otherwise directly collect in the gutter invert (24A).  The gutter protector (10) includes a spacer (30) for spacing adjacent profiled sheets (28) by a first gap (32) that allows water to the substantial exclusion of leaves and debris to fall through the gap (32) into the underlying gutter invert (24A).  The profiled sheet (28) includes a planer liquid impervious portion (34) having an outer edge (36) adjacent an outer wall (22) of gutter (12) and an inner edge (38) disposed to lie adjacent or in substantial alignment with a lower edge (40) of a roof covering (18).  A channel (48) is disposed adjacent to and extends along the inner edge (38) of planar portion (34).  Channel (48) has a base (50) below the planar portion and a first wall (52) that extends between the base (50) and inner edge (38).  The first wall (52) is provided with a plurality of holes (54) and a series of spaced apart ribs (56).  A second wall (60) extends upwardly from the opposite side of channel (48) and sits inside inner wall (20) of the gutter (12).
Patent NZ-523675-A (NZ)
Title: Adjustable sinker mould with one part movable relative to another part for different sized sinkers
Inventor: DAHYA DAVID DIPAK
IPC: A01K95/00
Filed: 2003-01-17
Abstract: Disclosed is a sinker mould with one or more parts movable relative to the main part of the mould so as to produce different sized sinkers.
Patent NZ-524971-A (NZ)
Title: Stereoscopic video capturing device and dual receiver with a three-dimensional viewer
Inventor: GUTIERREZ NOVELO MANUEL RAFAEL
IPC: H04N13/239
Filed: 2001-03-13
Abstract: A method for transmitting and receiving three-dimensional video images of a scene, using conventional transmission channels, comprises: (a) producing two independent video images taken from different view angles; (b) encoding, modulating and amplifying the data corresponding to the video image without any loss in frames, without any loss in color polarisation and without any field or frame multiplexion; (c ) transmitting the corresponding data from both video signals, with no mixing of the same, by independent and different video channels, left and right; (d) receiving and decoding the transmitted video data; (e) independently and simultaneously displaying one of the video images from the stereoscopic camera on a left display of a viewer and the other of the video images from the stereoscopic camera on a right display of the viewer; and (f) recording the video images in coordinated recording systems , be they analog or digital.
Patent NZ-526142-A (NZ)
Title: Constructive arrangement for the starting system of an electric motor
Inventor: MEDEIROS NETO LUIZ MAGALHAES
IPC: H02P23/00
Filed: 2001-11-30
Abstract: A constructive arrangement for the starting system of an electric motor, comprises: a basic body (10) to which are mounted a cover, a starting device (30) and a motor protector (40), characterized in that the basic body (10) is provided, on an external face (11), with: a projecting rod (12) for affixing the capacitor ; a pair of first openings (13), for the fitting of respective terminals of a capacitor (2) to be coupled to the projecting rod (12), the pair of first openings (13) are arranged in alignment with a pair of first electric connectors (52) provided inside the basic body (10); a first energizing opening (15) for electric connection to the starting device (30); and a second energizing opening (16), for electric connection to the motor protector (40), the basic body (10) defining a first housing (17) for receiving the starting device (30) and is closed by the cover (20) opposite to the projecting rod (12) and provided with two receiving openings (21), which are aligned with a pair of female connectors (51) respectively and electrically connected to the first electric connectors (52) and lodged inside the basic body (10) for receiving two pins for electric connection to the motor, the motor protector (40) is provided with a female connector (41) for the introduction of a third pin for electric connection of the motor and which is mounted inside a second housing (18) laterally affixed to the first housing(17), the motor protector (40,40') is electrically associated with a contact pin (42) aligned with the second energizing opening (16).
Patent NZ-528034-A (NZ)
Title: Isothiazoloanthrones, isoxazoloanthrones, isoindolanthrones and derivatives thereof as JNK inhibitors and compositions and methods related thereto
Inventor: SAKATA STEVEN T
IPC: A61P13/12
Filed: 2002-02-13
Abstract: Isothiazoloanthrones, isoxazoloanthrones, isoindolanthrones, and derivatives thereof having the general formula (I) are disclosed. RO is -CH2-, -SO-, -O-, -SO2-, or -S-. Pharmaceutical compositions comprising a compound of formula (I) are also described. The use of a compound of general formula (I) for the manufacture of a composition, for treating or preventing a disease associated with modulation of JNK, is also disclosed. Compounds of general formula (I) are useful for the manufacture of a composition, for treating or preventing a disorder; wherein the disorder is rheumatoid arthritis; rheumatoid spondylitis; osteoarthritis; gout; asthma;; bronchitis; cystic fibrosis; inflammatory bowel disease; irritable bowel syndrome; mucous colitis; ulcerative colitis; Crohn's disease; gastritis; esophagitis; hepatitis; multiple sclerosis; endotoxin shock; psoriasis; eczema; dermatitis; atherosclerosis, restenosis following angioplasty; left ventricular hypertrophy; myocardial infarction; stroke; ischemic damage to heart, kidney, liver, or brain; transplant rejection; systemic lupus erythomatosus; pancreatitis; chronic obstructive pulmonary disease; conjunctive heart failure; a central or peripheral neurological degenerative disorder or for treating or preventing cancer. The cancer may be a solid tumor or leukemia.
Patent NZ-529758-A (NZ)
Title: A method comprising selecting corn hybrids of specific endosperm type and NDF content for use as a silage and/or a grain supplement
Inventor: BECK JAMES FREDERICK
IPC: A23K50/10
Filed: 2002-05-28
Abstract: A method for enhancing ruminant feed ration digestibility and utilization comprising selecting particular corn hybrids of specific endosperm type and NDF(neutral detergent fibre) content for use as corn silage and combining a supplemental corn grain, corn silage and other components to form a feed ration. The supplemental grain and corn silage are combined in amounts to provide environment for starch degradation and energy utilization.
Patent NZ-534018-A (NZ)
Title: Output shaft assembly for power tool, and power tool incorporating such assembly
Inventor: MILLION PHIL
Filed: 2004-07-09
Abstract: An output shaft for a jigsaw which is driven in a reciprocating motion relative to the tool housing while supporting a jigsaw blade is disclosed. The output shaft assembly includes an output shaft 20 of flat cross section and a pair of inserts 94 to form a region of circular cross section in order to allow the shaft 20 to pivot relative to scotch yoke mechanism 54 for driving the output shaft in a reciprocating motion relative to the tool housing. The shaft is supported by bearings at the non-circular regions, allowing the use of smaller bearings and a more compact arrangement than if a circular shaft of similar strength was used. A jigsaw incorporating the output shaft assembly is also disclosed.
Patent NZ-538052-A (NZ)
Title: Composition based on substituted 1,3-diphenylprop-2-en-1-one derivatives
Inventor: NAJIB JAMILA
IPC: A61P25/00
Filed: 2003-07-08
Abstract: Disclosed is a composition comprising at least one substituted 1, 3-diphenylprop-2-en-1-one derivatives of formula (I) for the treatment or prophylaxis of a pathology related to inflammation, neurodegeneration, deregulations of lipid and/or glucose metabolism, cell proliferation and/or differentiation and/or skin or central nervous system ageing.
Patent NZ-539836-A (NZ)
Title: Mask and components thereof
Inventor: BERTHON-JONES MICHAEL
IPC: A61M16/06
Filed: 2003-11-06
Abstract: A comfortable low-leak mask assembly for use with Non-Invasive Positive Pressure Ventilation (NIPPV) is provided to improve patient compliance and/or treatment. The mask system may include headgear having straps that are substantially inextensible and/or micro-adjustable; and/or a mask and/or cushion that includes various structures to allow enhanced/tailored sealing and/or fit at selected locations on the patient's face.
Patent NZ-541122-A (NZ)
Title: Polymer conjugates of cytokines, chemokines, growth factors, polypeptide hormones and antagonists thereof with preserved receptor-binding activity
Inventor: BHASKARAN SHYAM S
IPC: A61K6/00
Filed: 2003-12-23
Abstract: Disclosed is a method for synthesizing conjugates of one or more synthetic water-soluble polymers with a cytokine, a chemokine, a growth factor or a polypeptide hormone, or an antagonist thereof, that preserves more of the in vitro receptor-binding potency of said cytokine, chemokine, growth factor or polypeptide hormone, or antagonist thereof, than is preserved when such polymers are randomly coupled, comprising:
Patent NZ-542352-A (NZ)
Title: Polymeric modifiers and pharmaceutical compositions
Inventor: KASUYA YUJI
IPC: A61K47/48
Filed: 2004-03-24
Abstract: Disclosed is a copolymer or a pharmacologically acceptable salt thereof, which contains, as constitutional units: One or more structural units which may be the same or different from each other represented by formula (I) wherein: m is an integer from 3 to 100, and Alk represents an alkylene group; and R1 and R2 are the same or different and represent H or optionally substituted alkyl; and One or more structural units which may be the same or different from each other represented by the formula (II) wherein: R3 represents an OH, optionally substituted alkoxy, optionally substituted aryloxy, or -NR4R5 wherein R4 and R5 are as defined in the specification. Also disclosed are complexes of the said copolymer with proteins and the use of the copolymer in the manufacture of medicaments for retaining administered proteins in the bloodstream.
Patent NZ-550119-A (NZ)
Title: Method for storing biological material in a dissolvable matrix
Inventor: HERRNSTADT CORINNA
IPC: G01N35/00
Filed: 2005-04-08
Abstract: Disclosed is a method for storing biological material, comprising loading a liquid biological sample or biological material onto a matrix comprised of a material selected from polyvinylpyrrolidone, polyvinyl alcohol, polyethylene glycol, agarose, poly-N-vinylacetamide, poly(4-vinylpyridine), polyphenylene oxide, crosslinked acrylamide, polymethacrylate, polyactide, hydroxymethacrylate copolymer, and hydroxypropyl methylcellulose acetate succinate, the matrix material further including a stabilizing agent, wherein the matrix material is capable of absorbing, adsorbing or entrapping the biological sample and wherein the material dissolves in a solvent that allows at least 50 percent recovery of the dried sample after hydration, rehydration or other solvent reconstitution of the sample.
Patent NZ-550241-A (NZ)
Title: Container with portion adjacent to aperture that is deformable to allow handle flange to be moved inwardly and then into aperture
Inventor: CROOK ROSS
Filed: 2006-09-29
Abstract: A container has a portion 12, typically a skirt portion on a pail, that has an aperture 14 to receive a carry handle which has a handle 22 connected to a flange 20 via a shaft 4. In order to install the carry handle the container portion below the aperture 13 is resiliently deformable inwardly so that the flange inwardly and then upwardly to be captured by the container portion 12.
Patent NZ-551640-A (NZ)
Title: Process for the production of an influenza vaccine
Inventor: TREPAINIER PIERRE
IPC: C12N7/02
Filed: 2005-05-20
Abstract: A serially passaged and cloned Madin-Oarby Canine Kidney (MOCK)-derived cell line characterized in that it has a higher susceptibility to viral infection than its parental MOCK cell line, wherein said higher susceptibility is the capability to produce at least 1.2 fold greater titer of virus than produced in said parental cell line.
Patent NZ-556481-A (NZ)
Title: Abrasive articles comprising abrasive grains and colloidal composite binders
Inventor: YOU XIAORONG
IPC: B24D3/28
Filed: 2006-01-27
Abstract: Disclosed is an abrasive article comprising abrasive grains and a colloidal composite binder, the colloidal composite binder comprising at least about 5 wt% of a submicron particulate filler based on the weight of the composite binder.
Patent NZ-564044-A (NZ)
Title: Drill bit
Inventor: DURFEE LAVERNE
Filed: 2007-12-05
Abstract: A drill bit comprises a shank defining a longitudinal axis. A cutting head is formed at one end of the shank. At least one cutting edge and a centering point are formed on the cutting head. The shank and a portion of the cutting head are formed of a first material. The cutting edge, centering point and a portion of the cutting head are formed of a second material. A weld joins the first material and the second material. A first blank is welded to a second blank. A cutting head is milled into the first blank and second blank such that the cutting head is formed of the first material and the second material.
Patent NZ-569403-A (NZ)
Title: Spiroketals
Inventor: REDDELL PAUL WARREN
IPC: A61K31/02
Filed: 2006-12-22
Abstract: Disclosed is a spiroketal compound of formula (II) wherein Y and Z are -O- R50 is selected from methyl, cycloalkyl, aryl, heterocyclyl and heteroaryl and the further substituents are defined in the specification or a pharmaceutically, agriculturally or pesticidally acceptable salt thereof. Which can be extracted from a plant of family Lauraceae e.g. from the genus Litsea, Cinnamomum, Cryptocarya, Beilschmiedia, Endiandra, Neolitsea and Lindera. Also disclosed is a composition comprising said compound, the use of said compound in the manufacture of a medicament for treating disorders e.g. infections and cancer and a method to control pests by applying said compound to the environment.
Patent NZ-577902-A (NZ)
Title: Method and arrangement for damping of tower-oscillations
Inventor: BJERGE MARTIN
IPC: F03D11/00
Filed: 2009-06-23
Abstract: Method for damping the effects of tower-oscillations on delivered electrical power of a wind turbine is disclosed. Rotation of blades of the wind turbine is transformed into electrical power by a generator, which is located on top of the tower. The electrical power is transformed from AC to DC and back to AC by a converter, and a power-reference signal is used by the converter to control the delivered electrical power. A variable power-offset signal is added to the power-reference signal before it is used for control. The variable power-offset signal is calculated by a multiplication of a first signal, which represents the mean value of the power-reference-signal, and a second signal, which represents the side-to-side-oscillation of the tower.
Patent NZ-583350-A (NZ)
Title: Heteroaryl-hydantoin derivatives as bitter taste inhibitors
Inventor: LI XIAODONG
IPC: A23L27/20
Filed: 2008-08-19
Abstract: Disclosed are heteroaryl-hydantoin derivatives as represented by the general formula (I), wherein: Ar6 and Ar7 are the same or different, and independently one from the other are an optionally substituted five-membered heteroaryl group; Alk is an alkyl group; R?36 and R37 together with the atoms to which they are attached, form an optionally substituted five-membered heterocycle; and R38 is H, substituted or unsubstituted alkyl, substituted or unsubstituted cycloalkylalkyl, substituted or unsubstituted heterocycloalkylalkyl, substituted or unsubstituted aryl, substituted or unsubstituted arylamidoalkyl, substituted or unsubstituted heteroarylamidoalkyl, substituted or unsubstituted arylalkyl, substituted or unsubstituted arylalkoxy, substituted or unsubstituted heteroaryl, substituted or unsubstituted heteroarylalkyl, or haloalkyl. Representative compounds include 3-(1-((3,5-dimethylisoxazol-4-yl)methyl)-1H-pyrazol-4-yl)imidazolidine-2,4-dione; 5-benzyl-3-(1-((3,5-dimethylisoxazol-4-yl)methyl)-1H-pyrazol-4-yl)-1-methylimidazolidine-2,4-dione. Further disclosed is a food, beverage, or medicament composition having a bitter taste wherein said bitter taste is alleviated or eliminated by the addition of an effective amount of a compound as defined above or a salt or N-oxide thereof.
Patent NZ-584497-A (NZ)
Title: Assay system which includes an evaporation or freezing step
Inventor: SHEPHERD PETER ROBIN
IPC: A61K31/417
Filed: 2010-04-08
Abstract: Disclosed is a method of forming a plurality of re-constitutable doses of at least one drug in a plurality of wells, the method including the steps of (i) placing a known amount of said drug in a suitable carrier to form a first composition having a known concentration (ii) placing at least two selected amounts of that first composition into individual wells and (iii) converting the first composition into a transportable form by evaporation of the carrier or by freezing so that the first composition can later be converted into a second composition having a known concentration and (iv) sealing the wells.
Patent NZ-588240-A (NZ)
Title: Intermediate holder for the safety rope of an overhead rope system of a fall protection device, and arrangement consisting of the intermediate holder and a runner cooperating therewith
Inventor: MAHR THORSTEN
IPC: E04G21/32
Filed: 2009-03-27
Abstract: The intermediate holder (10) for a safety rope (38) of an overhead safety rope system comprises a base (12) and a yoke (14) which bears a guide tube (16), in which the safety rope (38) can be secured, and which is articulated at its upper end on the base (12) at an articulation point. At its lower end, the yoke (14) supports the guide tube (16) from below at an angle of 0 to 90° to the connection line between the articulation point of the yoke (14) on the base (12) and the guide tube (16). The yoke (14) is cut out in the form of a C such that it can engage laterally around a runner (not shown) guided on the safety rope (38)
Patent NZ-595917-A (NZ)
Title: Methods for improving pharmacokinetics
Inventor: TRAN JONATHAN Q
IPC: A61P31/12
Filed: 2010-04-22
Abstract: 595917 The disclosure relates to co-administration a compound of formula I (R7227) a NS3/NS4A protease inhibitor with a cytochrome P450 inhibitor wherein the cytochrome P450 inhibitor is ritonavir, to elevate the blood levels of the compound of formula I. The use of these compositions to treat Hepatitis C (HCV) is also disclosed.
Patent NZ-597256-A (NZ)
Title: Single stage, axial symmetric blower and portable ventilator
Inventor: CHALVIGNAC PHILIPPE AUGUSTE
IPC: A61M16/00
Filed: 2010-08-11
Abstract: A blower is disclosed. The blower (10) includes a housing including a proximal opening (23) and a distal opening (25) that are co-axially aligned, a stator component (30) provided to the housing, an impeller (60) positioned between the proximal opening of the housing and the stator component, and a motor adapted to drive the impeller (60). The impeller (60) includes a plurality of impeller blades. The stator component (30) includes a plurality of air directing grooves (35) along its exterior surface. The leading edge of the air directing grooves (35) extend tangentially outwards from the outer tips of the impeller blades and are configured to collect the air exiting the impeller blades and direct it from a generally tangential direction to a generally radial direction by dividing the air from the impeller and directing the air along a curved path towards the distal opening so that airflow becomes substantially laminar.
Patent NZ-598455-A (NZ)
Title: Compounds as tyrosine kinase modulators
Inventor: GUO XIALING
IPC: A61K31/4365
Filed: 2010-09-03
Abstract: ABSTRACT - 598455 The disclosure relates to a compound represented by Formula (I) e.g. 7-[3-fluoro-4-({ [(2-fluoro-5-methylphenyl)amino]carbonyl} amino)phenoxy]thieno[3,2-b]pyridine-2-carboxylic acid, wherein the variables are as defined in the specification. These compounds are suitable for the treatment of one of the diseases or conditions selected from the group consisting of colorectal cancer, lung cancer, hematological cancer, renal cancer, liver cancer, breast cancer, diabetic retinopathy, macular degeneration, age-related macular degeneration, retinopathy of prematurity, ocular angiogenesis, retinal edema, retinal ischemia, diabetic macular edema, cystoid macular edema, retinal vein occlusion, branch vein occlusion, preretinal neovascularization, laserinduced choroidal neovascularization, neovascularization associated with keratoplasty, glaucoma and ocular tumors, arthritis, restenosis, hepatic cirrhosis, atherosclerosis, psoriasis, diabetes mellitus, wound healing, inflammation, neurodegenerative diseases and immune disorders.