baber/WOPTO huggingface dataset:
Patent IL-82352-A0 (IL)
Title: 1,4-disubstituted piperazine derivatives,their preparation and pharmaceutical compositions containing them
IPC: C07D295/185
Filed: 1987-04-28
Abstract: The invention relates to novel 1,4-disubstituted piperazine derivatives of the general formula (I), pharmaceutically acceptable acid addition and quaternary ammonium salts thereof, pharmaceutical compositions containing them and a process for their preparation. In the general formula (I)    <IMAGE>  (I)  R1, R2, R3 and R4 are the same or different and stand for hydrogen or halogen or a trihalomethyl, lower alkyl, lower alkoxy, nitro, hydroxyl, aralkyloxy or an 1-(2-propenyl-4-piperazinyl) group; R5 stands for hydrogen or a C1-4 alkyl group; R6 represents a C3-6 alkyl, alkenyl, alkynyl group or a   <IMAGE>   group, wherein R7 means a C2-5 alkyl, alkenyl or alkinyl group; and is 2 or 3, with the provisos that: R6 is different from isopropyl, n-butyl and isobutyl group when R2, R3, R4 and R5 stand for hydrogen, R1 means 2-chloro and n is 2; R6 is different from isopropyl group when R2, R3, R4 and R5 stand for hydrogen, R1 means 2-chloro and n is 2; or when R2, R3, R4 and R5 stand for hydrogen, R1 means 2-methyl group and n is 2; and R6 is different from propionyl group when R1, R2, R3, R4 and R5 are hydrogen and n means 2. The compounds of the general formula (I) are therapeutically useful for the treatment of diseases arising from a hypofunction of the dopaminergic system.
Patent IL-85229-A0 (IL)
Title: Novel imidazo-and triazolothiadiazines,a process for the preparation thereof,pharmaceutical compositions containing same,and the use thereof
IPC: A61P37/00
Filed: 1988-01-28
Abstract: Imidazo- and triazolothiadiazines of the formula I 
<IMAGE>
 in which R<1> = C1-C4-alkyl,
 R<2> = H or C1-C3-alkyl
 and the structural element -A-B-
 = -CH2-CH2-, -CH=CH-, -CH=N-, -CH2-CO- or -CO-CH2-,
 and their physiologically tolerable acid addition salts are prepared by reaction of 2-halo-1-phenylalkanones of the formula II 
<IMAGE>
 with compounds of the formula III 
<IMAGE>
 and, if desired, conversion of the compounds of the formula I formed into their physiologically tolerable acid addition salts by means of suitable acids. 
<??>The compounds of the formula I and their physiologically tolerable acid addition salts are mainly suitable for the prevention and treatment of inflammatory diseases - in particular of inflammatory rheumatic diseases. 
<??>Some of the intermediates formed during the preparation of the compounds of the formula I are also new, i.e. 1-amino- 2-mercaptoimidazole 
<IMAGE>
 and 1-amino-2-thioxo-5-imidazolidinone 
<IMAGE>
Patent IL-90691-A0 (IL)
Title: Press-fit electrical terminal
IPC: H01R13/41
Filed: 1989-06-20
Abstract: An electrical contact terminal having a mounting section designed for press-fit insertion into a hole of a substrate such as a circuit board. The mounting section comprises an oblong base portion to which is secured at least one separately formed flexible fin. While the base portion and fin are both electrically conductive, they are not formed integrally from the same material and may be formed of two different materials. The fin or fins are secured to opposite sides of said base portion and are secured to said base portion at one or both ends. At one end, the fins are narrowed in width and thickness and secured to the base portion by means of electrical or laser welding. The fins may be mechanically clamped to the base portion at the other end. The terminals may be carried by a carrier strip and the fins may be preferably formed by punching a portion of said carrrier strip and bending it around said base portion of the terminal to form parallel fins extending on opposite lateral sides of the base portion. A process for manufacturing the electrical terminal is also disclosed.
Patent SE-8901609-A0 (SE)
Title: Strålsamlare för vattenkranar
Inventor: SVENSSON KJELL INGVAR
Filed: 1989-05-05
Abstract: Uppliuningen nvser en fungernnde straisamlare fOr tappkrsinar vat ten °eh andrn vatskor.
Patent SE-8901690-A0 (SE)
Title: Anordning vid ett fjädrande system
Inventor: BO LINDQUIST
IPC: F16F15/02
Filed: 1989-05-11
Abstract: iiciduliddoXuT (L1 '91) IIPIW VuelPults9; urtge;suolinPit Jelle/IP0 lucolleJduRP 4PnaPnlilduge wawa Wooed Unlei91 AM VPIAPTIVIdttle MVP OPUTIMAPAQ mild= tu Pew t uonexat4939 00 AV *PuePtiaddn 130 NA 31* agleu9I PAM '41)20911411dury ltuclexi Pueni91 VI 13* nadtrisx0Pun 'Mid= 1:44uW41114) Pew o truemilmi rift MuTou9/ poto As1.193 TIA WIRD euunli Ile VI Pegged= .111 Puol WIN deltsuegit Pinutnii (z) suoP *Poem* focanik;Imw4sAs ; 1W luins(s soputtwiddlt ) ants ue 'no put Immo= no JOSAV weatvuuddil
Patent AU-PP795498-A0 (AU)
Title: Object and document control system
IPC: G06K17/00
Filed: 1998-12-24
Abstract: An electronic tag for the identification and/or secure control of an object or document includes a microcircuit (15), means (13, 14) for communicating with an interrogator, and presence detection means such as a tuned circuit (16, 17). The presence detection means (16, 17) may be reversibly activated and deactivated, for example, via a programmable transistor (75) with a floating gate (77). The presence detection means (16, 17), when activated, can be operated at a lower interrogation signal power than is required for energising the microcircuit (15). The electronic tag may also have a second presence detecting means, such as a soft magnetic strip, which cannot be deactivated.
Patent FI-20020865-A0 (FI)
Inventor: KARJALAINEN MATTI
IPC: H04R3/04
Filed: 2002-05-07
Abstract: The present invention relates to a method for designing a modal equalizer ( 5 ) for a low frequency audible range, typically for frequencies below 200 Hz for a predetermined space ( 1 ) (listening room) and location ( 2 ) (location in the room) therein, in which method modes to be equalized are determined at least by center frequency and decay rate of each mode, creating a discrete-time description of the determined modes, and determining equalizer filter coefficients on the basis of the discrete-time description of the determined modes, and forming the equalizer ( 5 ) by means of a digital filter by defining the filter coefficients on the basis of the properties of the modes. In accordance with the invention following method steps are used: forming a mode detection function (G(Omega)), defining the highest peak angular frequency Omega<SUB>p </SUB>of the function (G(Omega)), making AR analysis of predefined order for solving the poles of the mode representing the highest peak angular frequency, selecting the pole closest to point e<SUP>jOmegap </SUP>on the unit circle, determining the decay time of the mode and if is over a predetermined level, designing a modal correction filter for this mode, and repeating this procedure until no decay time exceeds over the predetermined level, and each individual filter obtained in previous stages of the method is combined to a cascaded filter.
Patent IL-101352-A0 (IL)
Title: Topical preparation containing a suspension of solid lipid particles and its manufacture
IPC: A61K8/30
Filed: 1992-03-24
Abstract: An aqueous suspension of solid lipoid nanoparticles, comprising at least one lipid and preferably also at least one emulsifier, is provided for topical application to the body, wherein the lipid is a solid lipid, selected from the group consisting of:     higher saturated alcohols;   sphingolipids;   synthetic esters;   higher fatty acids of 12-30 carbon atoms and mono-, di- and triglycerides of higher saturated fatty acids having 10 - 30 carbon atoms.   Optionally the suspension of solid lipoid nanoparticles contains a drug. A manufacturing method for the said aqueous suspension of solid lipoid nanoparticles is also provided.
Patent IL-115007-A0 (IL)
Title: Process for making sulfonyl isocyanates
IPC: C07C303/36
Filed: 1995-08-21
Abstract: This invention relates to an improved method of making sulfonyl isocyanates from the corresponding sulfonamides and phosgene.
Patent IL-122716-A0 (IL)
Title: System and method for in vivo delivery of autonomous capsule
IPC: A61B17/28
Filed: 1997-12-22
Abstract: A device for delivering autonomous capsules into the G.I. tract is provided. The device includes an endoscope (10) having a longitudinal axis (25) and a clamp (14) for releasably holding the capsule (12) whereby the longitudinal axis of the capsule (24) lies along the same axis as the longitudinal axis of the endoscope. The clamp (14) is held in the front of the endoscope by at least one support (16). A forward looking imaging unit (20) is also situated at the front end of the endoscope.
Patent IL-128127-A0 (IL)
Title: System for electric generation heating cooling and ventilation
IPC: H02N/
Filed: 1997-07-16
Abstract: An energy system that couples or integrates an electrochemical converter, such as a fuel cell for the production of electricity, with a Heating, Ventilation and Cooling (HVAC) system, is disclosed. Waste heat generated by the fuel cell is radiatively, convectively, or conductively directed to a thermal component, such as a heat-actuated chiller or a boiler, of an HVAC system. The HVAC system receives the waste heat to produce a conditioned fluid, e.g. heated or cooled air or water, or steam, for heating, cooling, or industrial uses. The invention provides an improved efficiency energy system capable of providing electricity, heating and cooling, such as for a commercial facility or for residences. Also disclosed in an interface exchange element for convectively coupling an electrochemical converter to the HVAC system. The interface exchange element receives heated exhaust gases generated by the fuel cell and extracts heat therefrom for transfer to a thermal component, such as heat-actuated chiller or a boiler, of an HVAC system.
Patent IL-128809-A0 (IL)
Title: Characterising dna
IPC: C12Q1/6837
Filed: 1997-09-05
Abstract: A method for characterizing cDNA, which comprises: (a) cutting a sample comprising a population of one or more cDNAs or isolated fragments thereof, each having a strand complementary to the 3' poly-A terminus of an mRNA and bearing a tail, with a first sampling endonuclease at a first sampling site of known displacement from a reference site proximal to the tail to generate from each cDNA or isolated fragment thereof a first and second sub-fragment, each comprising a sticky end sequence of predetermined length and unknown sequence, the first sub-fragment bearing the tail; (b) sorting either the first or second sub-fragments into sub-populations according to their sticky end sequence and recording the sticky end sequence of each sub-population as the first sticky end; (c) cutting the sub-fragments of each sub-population with a second sampling endonuclease, which is the same as or different from the first sampling endonuclease, at second sampling site of known displacement from the first sampling site to generate from each sub-fragment a further sub-fragment comprising a second sticky end sequence of predetermined length and unknown sequence; and (d) determining each second sticky end sequence; wherein the aggregate length of the first and second sticky end sequences of each sub-fragment is from 6 to 10; and wherein the sequences and relative positions of the reference site and first and second sticky ends are utilized to characterize said cDNA or cDNAs.
Patent IL-129829-A0 (IL)
Title: Method for chemical vapour infiltraton of refractory substances especially carbon and silicon carbide
IPC: C04B41/50
Filed: 1997-11-07
Abstract: A method for isothermic, isobaric chemical vapor infiltration (CVI) of refractory substances, especially of carbon (C) and silicon carbide (SiC), based on diffusion in a porous structure, whereby the pressure of the gas or partial pressure of an educt gas contained in the gas and the dwell time of the gas in the reaction zone are set at a given temperature in the reaction zone so that a deposition reaction occurs in the porous structure in the area of pressure or partial pressure of the saturation adsorption of the gaseous compounds forming the solid phase, saturation adsorption meaning that the deposition speed remains substantially constant at increased pressure of the gas or partial pressure of the educt gas. The reaction of the educt gas is limited in such a way that no more than 50% of the elements in the educt gas as it flows through the reaction zone are deposited as a solid phase in the porous structure.
Patent IL-130433-A0 (IL)
Title: A medicament container of polymer of linear olefin for storing a liquid medicament
IPC: A61J1/05
Filed: 1997-12-16
Abstract: A medicaments, container for storing a liquid medicament comprising one or more active medicaments, water and at least one preservative has a preferably cylindrical wall defining an interior space for such liquid medicament. The wall includes at least two opposed portions composed of a polymer material with a thickness of between 0.3 mm and 3 mm, a light transmission at 400 nm of 25% or more measured through the opposed container wall portions when the container is filled with water, using a standard spectrophotometer and air as reference. The polymer wall portions are of a material comprising at least 70% by weight of a linear optionally branched polyolefin material, the olefin monomer being selected from ethylene, propylene, butylene or a mixture thereof The polyolefin material has a crystallinity above 35% by weight, measured by differential scanning calorimetry, by cutting pieces from the container walls and heating them in an aluminum pan from 10 DEG  C. to 270 DEG  C. at the scanning rate of 10 DEG  C./min, recording and integrating the melting endotherms, and using the value of 209 J/g for 100% crystalline polypropylene as a reference.
Patent IL-135752-A0 (IL)
Title: Use of cellulose microfibrils in dry form in food formulations
IPC: A23L29/262
Filed: 1998-10-16
Abstract: The invention concerns the use, in dry form, of a combination of substantially amorphous microfibrils with a crystallinity index not more than 50%, with at least a polyhydroxylated compound, as additive for food formulations, the content of this combination being more than 0% and less than 20% by weight relative to the total weight of the food formulation.
Patent IL-155367-A0 (IL)
Title: NOVEL 2,4,8-TRISUBSTITUTED-8h-PYRIDO[2,3,-d]PYRIMIDIN-7-ONE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, PROCESSES FOR THE PREPARATION THEREOF, AND USE THEREOF IN THE PREPARATION OF MEDICAMENTS FOR TREATING CSBP/p38 KINASE MEDIATED DISEASES
IPC: A61P31/12
Filed: 2001-10-23
Abstract: Novel substituted 2,4,8-trisubstituted -8H-pyrido[2,3-d]pyrimidin-7-one compounds and compositions for use in therapy as CSBP/p38 kinase inhibitors.
Patent IL-156204-A0 (IL)
Title: Method and apparatus for selection of inkjet printing parameters
IPC: B41J2/01
Filed: 2001-12-20
Abstract: Methods and apparatus for inkjet printing include automated techniques for selecting and/or adjusting printing parameters. The techniques include methods for altering test pattern images received on a substrate for assessing certain characteristics, such as adhesion of a particular ink to a particular substrate. A computer selects certain printing parameters based on an assessment of the altered test pattern images.
Patent IL-159474-A0 (IL)
Title: 1,2,4-trioxolane derivatives and pharmaceutical compositions containing the same
IPC: C07D493/10
Filed: 2002-06-21
Abstract: A means and method for treating malaria using a spiro or dispiro 1,2,4-trioxolane is described. The preferred 1,2,4-trioxolanes include a spiroadamantane group on one side of the trioxolane group, and a spirocyclohexyl or spiropiperidyl ring on the other side of the trioxolane group, whereby the spirocyclohexyl ring is preferably functionalized or substituted at the 4-position or a spiropiperidyl ring that is functionalized or substituted at the nitrogen atom. In comparison to artemisinin semisynthetic derivatives, the compounds of this invention are structurally simple, easy to synthesize, non-toxic, and potent against malarial parasites.
Patent IL-188610-A0 (IL)
Title: Novel anti-allergic agents
IPC: A61P25/06
Filed: 2008-01-06
Abstract: The present invention discloses novel complex molecules useful as anti-allergic agents. These complex molecules include in particular, peptidic or peptidomimetic molecules, having a first segment which is competent for cell penetration and a second segment which is able to reduce or abolish mast cell degranulation, and in particular to reduce or abolish allergy mediators such as histamine secretion from mast cells. Specific examples of peptides with the desired activity are disclosed.
Patent IL-188905-A0 (IL)
Title: Container closure assembly
Filed: 2008-01-21
Abstract: A closure assembly has a closure cap (2) adapted to be fitted to the neck of a container to close the container. The cap (2) has an upper wall (4) and a cylindrical skirt (5) depending therefrom. A reservoir (7) is formed on the underside of the upper wall (4) radially within the skirt (5) and has a dispensing opening (9). A sealing member (3) is fitted into the closure cap (2) to close the dispensing opening in the reservoir. When the assembly is fitted to the container the sealing member fits into the neck of the container with an interference fit such that when the closure cap (2) is removed from the container, the sealing member (3) remains held within the neck of the container and is separated from the closure cap so that the dispensing opening is opened and material contained therein is dispensed into the container.
Patent IL-210782-A0 (IL)
Title: Cross-flow filtration apparatus with biocidal feed spacer
Filed: 2011-01-20
Abstract: A cross-flow filtration apparatus is provided. The cross-flow filter is a spiral wound filter that includes a semi-permeable membrane wrapped around a perforated central tube. The semi-permeable membrane includes a feed spacer and a membrane. The feed spacer is a biocidal feed spacer with a biocidal agent impregnated within the feed spacer to prevent biofouling of the feed spacer and the membrane.
Patent RO-128326-A0 (RO)
Title: Architecture for optimizing the manufacturing processes in enterprises
Inventor: ITU ALINA
IPC: G05B19/042
Filed: 2012-10-04
Abstract: The invention relates to an architecture for optimizing the manufacturing processes in enterprises, both relating to the manufacturing time and to the installing time. According to the invention, the architecture consists of three main components: the first one is an OPC UA server (OLE for Process Control Unified Architecture) which models a series of data at the level of the devices used during the manufacturing process, and for efficiently carrying out the address space there was designed a set of algorithms which automatically generate the UA nodes of the address space based on the data source content; the second component consists of a series of software services organized on two levels, having the role of offering an easier communication between the higher level CSP (Constraint Satisfaction Problems) and the lower level OPC UA, these services being introduced at the second level, because they guarantee the flexibility and the reuse of the entire architecture; and the third component consists of a set of CSP models which determine the optimized production solutions and which are automatically used by means of the architecture.
Patent RO-132691-A0 (RO)
Title: System for motor-actuation of the carriage with the cut-out switch for connecting/disconnecting the same in medium voltage cells
Inventor: TUREAC VASILE
IPC: H01H3/42
Filed: 2017-12-11
Abstract: The invention relates to a carriage actuation system used in order to connect and disconnect the cut-out switch located on a carriage, in medium voltage electrical cells. According to the invention, the system comprises a housing (B) which consists of a bottom plate (5), side walls (6, 8), a frontal plate (10), and in which there are a direct current motor (24), provided with a reducer (25), a direct current motor for driving a cam (30), mounted on a support (18) and provided with a reducer (31) which mechanically blocks the cut-out switch while connecting/disconnecting, where the motor for driving a cam (30) is provided with a driving shaft (32) on which a grooved coupling (D), is mounted and is coupled when a cam shaft (E) is automatically actuated and which is uncoupled by means of a shaft (33) when the cam shaft (E) is manually actuated.
Patent AP-2000002016-A0 (AP)
Title: 2-(Purin-9-yl) Tetrahydrofuran-3,4-diol derivatives.
Inventor: ALLEN DAVID GEORGE
IPC: C07H19/16
Filed: 1999-06-23
Abstract: There are provided according to the invention, novel compounds of formula (i)wherein R1, R2 and R3 are as defined in the specification, processes for preparing them, formulations containing them and their use in therapy for the treatment of inflammatory diseases.
Patent IE-910147-A1 (IE)
Title: A novel vector to produce biologically important peptides
IPC: C07K14/245
Filed: 1991-01-17
Abstract: In this patent application we have described the construction of a novel secretion vector based on E.coli enterotoxin coding sequence. We have shown categorically that pre and pro region of toxin gene are absolutely necessary for extracellular secretion of the stable toxin. We have also shown with specific examples that when the nucleotide coding sequence of a heterologous peptide is fused in frame to the end of the pro region in the st gene, the resultant vector in an E.coli host secretes extracellularly correctly processed heterologous peptide. This application also includes construction of suitable vectors where this gene fusion can be achieved. General methods to create such fusions involving a) recombinant DNA technology and b) the use of site directed in vitro mutagenesis, have also been described. A general method of purification of heterologous peptides is also described in this application. This novel vector system can be used for hyperproduction and extracellular secretion of peptides of biological importance.
Patent MA-18866-A1 (MA)
IPC: C10G1/02
Filed: 1980-06-02
Abstract: The invention pertains to a process of pyrolysis of shale capable of producing hydrocarbons. It comprises associating at least two retorts and causing their respective operational phases to be so coordinated as to achieve simultaneous pyrolysis of said materials in one of said retorts and treatment of the hot residues subsequent to an earlier pyrolysis in another of said retorts, said treatment comprising the discharging of the residues, the admission or supply into said other retort of crude or raw material as well as the recovery of the heat contained in the pyrolysis residues by means of a circulation therethrough of an oxidant gas, preferably air, and of initially pulverized or atomized water, the resulting mixture of oxidant gas and steam being then supplied into a retort in which a phase of pyrolysis is being run to assist the combustion of the carbonaceous residues formed as a result of the pyrolysis of the load of materials treated or pyrolyzed therein. When said pyrolysis in one of said retorts and the treatment of the residue in said other retort are both completed the modes of operation of said two retorts are alternated.
Patent MA-23068-A1 (MA)
Inventor: GUIDO BOLD
IPC: C07C243/20
Filed: 1993-12-23
Abstract: Compounds of the formula <IMAGE>  in which   R1 and R9, independently of each other, denote hydrogen, acyl or unsubstituted or substituted alkyl; sulpho; or sulphonyl which is substituted by unsubstituted or substituted alkyl, aryl or heterocyclyl, with the proviso that at most one of the radicals R1 and R9 denotes hydrogen; and R2 and R8, in each case independently of each other, denote hydrogen or unsubstituted or substituted alkyl; R3 and R4, independently of each other, denote hydrogen, unsubstituted or substituted alkyl, unsubstituted or substituted cycloalkyl or aryl;   R5 denotes acyloxy;   R6 denotes hydrogen; and R7 denotes unsubstituted or substituted alkyl, unsubstituted or substituted cycloalkyl or aryl; are described, as are salts of the said compounds, insofar as salt-forming groups are present; these compounds exhibit anti-retroviral activity.