baber/WOPTO huggingface dataset:
Patent CA-2252670-C (CA)
Title: Low ph acidic compositions
Inventor: GARCIA SILVERIO M
IPC: A61K47/12
Filed: 1996-04-29
Granted: 2002-11-05
Abstract: Low pH acidic compositions for chemical, pharmaceutical and cosmetic uses comprise two phases in solution. Phase I comprises about 2 to 98 weight % of several chemical, pharmaceutical and cosmetic substances. Phase II comprises about 2 to 98 weight % of an active aqueous acidic component having a pH value of less than about 1. This phase II aqueous acidic component is produced by:  (a) admixing 5 to 20 weight % of a strong acid having a high degree of dissociation with from 5 to 20 weight % of another strong acid having a lower degree of dissociation for an effective period of time to produce a substantially homogeneous acidic mixture; and (b) admixing from about 1 to 5 weight % of weaker acids with low degrees of dissociation selected from hydroxycarboxylic acids or alpha hydroxy acids and about 1 to 5 weight % of a dicarboxylic acid with the aqueous acidic mixture in an effective amount of water to provide an aqueous acidic mixture.
Patent CA-2254143-C (CA)
Inventor: KILGORE PATRICK M
IPC: H04N5/365
Filed: 1998-04-15
Granted: 2002-12-17
Abstract: Ce procédé adaptatif, destiné à enlever un bruit stable à partir d'images de cible focale, consiste à appliquer un ensemble facteurs de correction (26) à l'image focalisée, à partir de la cible focale et à appliquer un filtre (24C) à l'image corrigée et focalisée. On peut également appliquer l'ensemble facteurs de correction à une version floue de l'image de cible focale et appliquer le filtre à l'image corrigée et floue. Le procédé consiste ensuite à calculer les erreurs de bruit stable au moyen des images filtrées, à utiliser ces erreurs pour mettre à jour les facteurs de correction, puis à employer ces facteurs mis à jour pour traiter l'image suivante. Dans un mode de réalisation, le filtre est un filtre anti-médian, et dans un autre mode de réalisation, le filtre est un filtre anti-moyenne.
Patent CA-2255220-C (CA)
Title: Efficient high latitude service area satellite mobile broadcasting systems
Inventor: BRISKMAN ROBERT D
IPC: H04B7/19
Filed: 1998-12-21
Granted: 2011-11-29
Abstract: Satellite audio broadcasting systems include orbital constellations for providing high elevation angle coverage of audio broadcast signals from the constellation's satellites to fixed and mobile receivers within service areas located at geographical latitudes well removed from the equator.
Patent CA-2255946-C (CA)
Title: Dispositif d'insonorisation pour voies ferrees
Inventor: NEUMANN BERNHARD
IPC: E01B19/00
Filed: 1997-05-23
Granted: 2006-03-14
Abstract: L'invention concerne un dispositif d'insonorisation de voies ferrées (1), comportant des plaques (3) à absorption acoustique montées au niveau des rails (2) de la voie ferrée (1), qui s'appuient sur les rails par l'intermédiaire de profilés (5) élastiques et recouvrent de manière non soutenue l'espace entre les rails (2). Pour améliorer l'insonorisation des plaques (3), il est prévu que lesdites plaques (3) se composent de particules (9) en matériau poreux pour construction légère, agglomérées avec un liant. Les plaques (3) présentent une armature (11) encastrée. Avantageusement, il est également prévu dans les plaques (3), des cavités résonnantes (14) amortissant le bruit. Dans un mode particulier de réalisation, il est prévu que l'espace entre les rails (2) d'une voie soit recouvert de plaques partielles (3a, 3b) appariées, qui s'appuient mutuellement les unes sur les autres au niveau de leurs bords adjacents.
Patent CA-2263481-C (CA)
Inventor: VAN HOUTEN RONALD
IPC: F21S8/00
Filed: 1997-07-31
Granted: 2006-05-30
Abstract: An apparatus and a method for prompting pedestrians to look and listen for turning vehicles includes an animated pictorial message formed in the image of a pair of scanning eyes (46, 48) and generated by a pedestrian signal control (54) connected to a pedestrian signal display (32). The image (46, 48) can be activated by a traffic control (52) or a motion detector (64) connected to the pedestrian signal control (54).      A voice circuit (56) and speakers (58) connected to the pedestrian signal control (54) generate an audible message at the same time the image (4b, 48) is being displayed.
Patent CA-2266363-C (CA)
Inventor: IWAKI YOICHI
IPC: A61K9/08
Filed: 1997-09-24
Granted: 2007-05-22
Abstract: The present invention relates to a corneal subepithelial opacity (haze) inhibitor comprising as the active ingredient N-(3,4-dimethoxycinnamoyl)anthranilic acid represented by the formula: (see formula I) or a pharmaceutically acceptable salt thereof, is useful for the prevention or treatment of corneal subepithelial opacity (haze) caused by a wound during the operation of refractive surgery such as keratectomy and radial keratotomy, and an external wound.
Patent CA-2269053-C (CA)
Title: Crystals of benzimidazole derivatives and their production
Inventor: KATO MASAYASU
IPC: A61K31/4439
Filed: 1997-11-13
Granted: 2006-07-18
Abstract: A substantially solvent-free and stable crystal of the compound of formula (I) wherein the ring A may optionally be substituted R1 represents hydrogen or an N-protecting group, each of R2, R3 and R4 is (1) a hydrogen atom, (2) an alkyl group which may optionally be substituted with halogen atom(s) or (3) an alkoxy group which may optionally be substituted with halogen atoms(s) or alkoxy; or its salt, is produced by subjecting a solvate of the compound (I) or its salt to de-solvent treatment, in an industrially advantageous method.</SDOAB >
Patent CA-2274258-C (CA)
Inventor: KRESNYAK STEVE
IPC: C02F1/04
Filed: 1998-01-14
Granted: 2006-10-17
Abstract: There is disclosed a method and apparatus for removing a contaminant from a fluid feed stream containing the contaminant. The method includes comprising the steps of providing a feed stream (10) and heating it in a first step (18) to at least partially remove some of the contaminants and recover energy from a concentrate and distillate generate. Further heating the feed stream in a second heating step (20) in a heated separator generates a saturated vapour fraction (30) and a concentrate liquid contaminant fraction. The vapour fraction may be compressed (32) to generate a temperature differential in the reboiler exchanger (34) with the vapour fraction being passed into contact with a reboiler exchanger to provide a stream of condensed vapour from the reboiler. The stream may be circulated through the reboiler exchanger and the heated separator to maintain from about 1 % to about 50 % by mass vapour in the stream. The apparatus includes a unique configuration of a vapour compressor, heated separator in combination with a forced circulation (42, 44, 38) circuit to generate the decontamination result.
Patent CA-2275272-C (CA)
Inventor: FASSKE WAYNE C
IPC: B23D35/00
Filed: 1997-12-23
Granted: 2001-10-30
Abstract: Dans un appareil de cisaillement de pièces à parois multiples, notamment des montants d'ossature métallique, un support de base (16) définit un espace pour lame (18) et une lame du type guillotine (30) qui se loge de façon coulissante dans l'espace, afin de cisailler les pièces à usiner. Cet appareil comprend: une paire de premiers supports (20) dont chacun est monté de manière coulissante sur un support (16, 18) de base respectif, et une paire de seconds supports (22) également montés de manière coulissante sur le support de base, séparés entre eux et faisant face aux premiers supports, la distance qui les sépare définissant un canal (28) de largeur réglable. Chacun des supports définit un bord du type lame destiné à entrer en contact avec une pièce allongée et à parois multiples, et les premières et secondes surfaces du support sont chacune déplacées pour entrer en contact avec une paroi respective de la pièce. Les supports peuvent être orientés les uns par rapport aux autres de sorte que l'axe du canal et l'axe longitudinal de la pièce déposée dans le canal puissent former un angle désiré par rapport à la lame. La lame de type guillotine est alors dirigée vers le bas afin de pénétrer la pièce et la cisailler selon une ligne de contact.
Patent CA-2279806-C (CA)
Title: Non-linear optical silica thin film manufacturing method and non-linear optical silica element
Inventor: KOMEDA OSAMU
IPC: C03C17/245
Filed: 1999-08-09
Granted: 2004-11-16
Abstract: A non-linear optical silica thin film whose main material is SiO2-GeO2 is formed by irradiating with positive or negative polar particles such that polarization orientation is carried out in the silica thin film. A silica thin film is deposited on a substrate. At stages during deposition the silica thin film is irradiated with positive particles, neutral particles or non-irradiation of particles, and negative particles, thereby forming a plurality of regions having different states of polarization orientation that are in a direction of film thickness of the silica thin film. Thus, without carrying out a post process of polarization orientation, such as an application of voltage, a polarization orientation process is completed with formation of the silica thin film.
Patent CA-2279883-C (CA)
Title: Adaptive frequency reuse plan
Inventor: HENSON STEVEN RAY
IPC: H04W16/12
Filed: 1998-02-06
Granted: 2005-08-09
Abstract: A cell pattern for use with a frequency reuse plan is disclosed. Seven clusters (5) each comprising N cells per cluster are grouped together as a modified cluster (40). Each cell is further divided into three sectors (70). The total number of available frequency channels are divided into a F times seven (F*7) number of groups. Frequency channels associated with a group are then assigned to each of the cells within the modified cluster. In order to increase call capacity within a particular sector, a frequency channel previously assigned to a corresponding sector within the same cell group is reused.      Within a continuing increase in channel re-usage within a particular modified cluster, the (N*7)/(F*7) reuse plan is gradually lowered to the original N/F reuse plan without re-configuring the frequency allocation throughout the network.
Patent CA-2288417-C (CA)
Inventor: CHANG SHU-CHIEH
IPC: G01G19/08
Filed: 1999-11-03
Granted: 2004-01-13
Abstract: A structure which supports a device holding the material to be lifted is movable to locate the device in loaded and unloading positions. Apparatus for measuring the quantity of material delivered by the device comprises means to provide a processable position signal indicative of a determined position of the device, means to produce a processable load signal indicative of the determined load at a location within the structure, and processing means to receive the position and load signals for a plurality of interval determinations and calculate therefrom a number of weight determinations of the device and device contents, to select a sample of less than all of the weight determinations based upon the dynamic influences on the machine when the signals are processed, and to average the sample of selected weight determinations to provide a final weight determination of the device and device contents.
Patent CA-2290485-C (CA)
Inventor: ADAIR FIONA SUZANNE
IPC: C07K16/46
Filed: 1998-05-21
Granted: 2008-08-05
Abstract: Selon cette invention, des protéines, ou parties de protéines, peuvent être rendues non immunogènes, ou moins immunogènes, vis à vis d'une espèce donnée et ce, d'une part, grâce à l'identification dans les séquences d'acides aminés de ces protéines, d'un ou de plusieurs épitopes potentiels associés aux lymphocytes T de l'espèce donnée et, d'autre part, par modification de la séquence d'acides aminés dans le but d'éliminer au moins un des épitopes associés aux lymphocytes T. Ce procédé élimine ou réduit l'immunogénicité de la protéine lorsqu'elle est exposée au système immunitaire de l'espèce donnée. Des anticorps monoclonaux et d'autres molécules du type immunoglobulines peuvent présenter un avantage particulier après avoir été ainsi rendues non immunogènes, ou moins immunogènes, par exemple, les immunoglobulines extraites de souris peuvent être rendues non immunogènes, ou moins immunogènes, aux fins d'une utilisation thérapeutique chez l'être humain.
Patent CA-2300991-C (CA)
Title: Appareillage de sechage des corps poreux humides a des temperatures et pressions sous-critiques
Inventor: KIRKBIR FIKRET
IPC: F26B21/14
Filed: 1998-07-16
Granted: 2007-10-09
Abstract: L'invention concerne un dispositif perfectionné, ainsi que le mode de fonctionnement de celui-ci, permettant de sécher rapidement de grands monolithes de verre, de céramique et/ou de matériau composite, dans des conditions sous-critiques, le risque de craquage du monolithe étant minimisé lors du processus de séchage. Ce dispositif comprend une chambre de pression (15), dans laquelle le monolithe (11) à sécher est porté, sans limitation importante de la dimension du monolithe par rapport à celle de la chambre. On immerge d'abord le monolithe (11) dans un solvant de séchage approprié (23) et on élève la température de la chambre de pression (15) jusqu'à ce qu'elle atteigne une valeur déterminée se situant en dessous de la température critique du solvant, ce qui a pour effet d'élever la pression à une valeur déterminée se situant également en dessous de la pression critique du solvant. A un moment choisi pendant le processus de séchage, on relie la chambre de pression (15) à une chambre de diffusion (23), afin de retirer de la première chambre la vapeur de solvant et de la condenser dans la seconde chambre. Cet enlèvement de la vapeur de solvant continue jusqu'à ce que le monolithe (11) soit sec, moment auquel on purge la chambre de pression (15) à l'aide d'un gaz inerte et on abaisse la pression de manière régulée dans cette chambre. Ce dispositif est donc conçu pour sécher le monolithe à une pression sous-critique encore plus basse que celle utilisée dans des dispositifs de ce type existants, et il offre en conséquence des conditions de sécurité accrues et ces coûts de fonctionnement réduits.
Patent CA-2302230-C (CA)
Inventor: JEONG DEOG-KYOON
IPC: G09G3/36
Filed: 1998-09-04
Granted: 2004-11-16
Abstract: Switches and capacitors are efficiently used to passively change the voltag e level on column electrodes without active driving by the column driver circuit. This significantly reduces the power needed by the column driver circuit to drive voltages of alternating polarity onto the column electrodes. In this way, significant power is saved in both the pixel inversion and the row inversion schemes. The average power savings of various of the embodiments exceeds 50 % compared with a simple conventional implementation of a column driver circuit. Another aspect similarly reduces the power used by the column driver circuit in the back plane switching scheme.
Patent CA-2306692-C (CA)
Title: Dipeptide apoptosis inhibitors and the use thereof
Inventor: KEANA JOHN F W
IPC: A61P29/00
Filed: 1998-10-09
Granted: 2010-09-21
Abstract: The present invention is directed to novel dipeptides thereof, represented by general Formula (I) where R1-R3 and AA are defined herein. The present invention relates to the discovery that compounds having Formula (I) are potent inhibitors of apoptotic cell death. Therefore, the inhibitors of this invention can retard or block cell death in a variety of clinical conditions in which the loss of cells, tissues or entire organs occurs.
Patent CA-2315669-C (CA)
Title: Apparatus and method for cleaning debris from wells
Inventor: WAGG BRIAN
IPC: E21B21/00
Filed: 2000-08-11
Granted: 2007-06-12
Abstract: The invention consists of a system and method for restarting a downhole pump that has seized due to an accumulation of sediment above the pump and around the pump intake. The system consists of a flexible sealing element fitted on a joint of production tubing where the se al can be activated by pumping fluid down the well annulus. The tool includes tubing and check valv e arrangements such that fluid from the well annulus can enter the production tubing immediately above the downhole pump and circulate debris back to surface as well as introduce fluid to the pump intake to mobilize sand accumulated at the pump intake.
Patent CA-2322248-C (CA)
Title: A brush assembly
Inventor: RUUSKA MAUNO
IPC: E01H1/05
Filed: 2000-10-04
Granted: 2009-05-05
Abstract: A brush assembly in a movable sweeper said sweeper having a vehicle frame to which a rotatable cylindrical brush is connected, said brush having a rotation axle, a rotation motor, a frame and a shield to guide the brushed particles, said brush frame being coupled to the vehicle frame with a vertical axle wherein said brush frame being able to be turned to throw, when rotating, the particles to the right or left in relation to the vehicle driving direction, the sweeper moreover comprising a turning equipment to turn said brush frame round the vertical axle wherein the turning equipment comprises: a first hydraulic cylinder by means of which an articulated auxiliary bar is turned around its vertically directed articulating joint, a second hydraulic cylinder being fixed to said auxiliary bar from its one end and being fixed to the brush frame from its other end, the working positions of the brush are obtained by driving the second cylinder to its longest or correspondingly shortest position and the transporting position for the brush is obtained by driving the first cylinder to its extreme position.
Patent CA-2326045-C (CA)
Title: Pde iv inhibiting pyridine derivatives
Inventor: FREYNE EDDY JEAN EDGARD
IPC: A61P37/08
Filed: 1999-03-24
Granted: 2008-12-09
Abstract: The present invention concerns pyridine derivatives having formula (I), the N-oxide forms, the pharmaceutically acceptable addition salts and the stereochemically isomeric forms thereof, wherein L is hydrogen;  C1-6alkyl; C1-6alkyl carbonyl; C1-6alkyloxycarbonyl;  substituted C1-6alkyl; C3-6alkenyl; substituted C3-6alkenyl; piperidyl;  substituted piperidyl; C1-6alkylsulfonyl or arylsulfonyl; -A-B-is -CR4-CR5- or -CHR4-CHR5-; D is O or NR6; R1 is a hydrogen or C1-4alkyl; R2 is hydrogen; halo; C1-6alkyl; trifluoromethyl;  C3-6cycloalkyl; carboxyl; C1-4alkyl oxycarbonyl; C3-6cycloalkylaminocarbonyl;  aryl; HET1; or substituted C1-6alkyl; or R2 is aR9 or NH-R10; R3 is hydrogen, halo, hydroxy, C1-6alkyl or C1-6alkyloxy; or R2 and Ri, or R2 and R3 taken together may form a bivalent radical; Q is disubstituted pyridine; R7 and R8 each independently are hydrogen; C1-6alkyl; difluoromethyl; trifluoromethyl;  C3-6cyclo alkyl; a saturated 5-, 6- or 7-membered heterocycle containing one or two heteroatoms selected from oxygen, sulfur or nitrogen; indanyl; 6,7-dihydro-5H-cyclopentapyridyl; bicyclo[2.2.1)-2-heptenyl; bicyclo[2.2.1]heptanyl; C1-6alkylsulfonyl; arylsulfonyl; or substituted C1-10alkyl; having PDE IV and cytokine inhibiting activity. The invention also relates to processes for preparing the compounds of formula (I), pharmaceutical compositions thereof and their use as a medicament.
Patent CA-2329161-C (CA)
Inventor: FLISRAM DENNIS GERHEART
IPC: B24B3/36
Filed: 2000-12-20
Granted: 2009-11-10
Abstract: An apparatus and method for honing, sharpening or grinding a curved peripheral cutting surface of a slicer blade are provided. Included is the use of one of a set of interchangeable cams that generally follows the curved shape of the blade cutting surface, whether same has a constant radius or varying radii. The honing is accomplished off-line of the slicer equipment, and the movement of two honing or grinding wheels is closely controlled so as to provide honed or ground cutting edges which are of substantially uniform width throughout their respective peripheries. The two honing or grinding wheels operate independently of each other on opposing edges of the blade, a large blade load area is provided therebetween, precision gib adjustments are provided between the wheel and the cam follower, and a single tool is needed to make adjustments of the apparatus.
Patent CA-2331459-C (CA)
Title: Dispositif tampon
Inventor: HAAB KARL
IPC: E05F5/00
Filed: 2000-03-14
Granted: 2008-08-12
Abstract: L'invention concerne un dispositif tampon (10) présentant un corps (11) qui peut être monté dans un rail (4), un élément d'amortissement (12) pour amortir un mécanisme de roulement (6) qui est guidé dans le rail (4) et sert à supporter et à guider des éléments de battant (2) coulissants, ainsi qu'un ressort de maintien (13) servant à maintenir ledit mécanisme de roulement. Le corps (11) du dispositif tampon (10), qui est cintré et découpé dans un élément métallique et présente au moins approximativement la forme d'un profilé en U, comprend un premier et un deuxième bras (14 ; 18) qui sont reliés par un élément central (20) dont le prolongement en forme de languette forme le ressort de maintien (13) servant à maintenir ledit mécanisme de roulement. Les parties terminales (17, 19, 26; 17*, 19*) des bras (14; 18) sont conçues de sorte qu'elles puissent maintenir l'élément d'amortissement (12). Ce dispositif (10) peut être produit de manière économique à partir d'une seule plaque métallique et complété par un élément d'amortissement (12). Le dispositif tampon (10) présente une stabilité élevée car le ressort de maintien (13) fait partie intégrante du corps (11) du dispositif tampon.
Patent CA-2334047-C (CA)
Inventor: WALDMANN HERMAN
IPC: A61K39/395
Filed: 1999-07-21
Granted: 2015-11-24
Abstract: An IgG antibody is provided having a binding affinity for the CD3 antigen complex in which in the heavy chain has a variable region framework together with at least one CDR selected from the amino acid sequences of SEQ ID No 2, 4 and 6 and respective conservatively modified variants thereof and the light chain has a variable region framework together with at least one CDR selected from the amino acid sequences of SEQ ID No 8, 10 and 12 and respective conservatively modified variants thereof characterised in that the heavy chain variable region framework corresponds in sequence to the human type sequence and the light chain variable region framework includes one or more of the specific amino acids characteristic of the rodent type sequence. The novel antibody is capable of being expressed by mammalian cell expression systems at enhanced yields.
Patent CA-2339690-C (CA)
Inventor: KUHN STEPHEN R
IPC: B61L5/02
Filed: 2001-03-08
Granted: 2007-08-28
Abstract: An improved railroad trackwork spring wing frog assembly having a selectively releasable hold-open subassembly for the spring wing rail is provided with a combined compressible shock absorber and compression spring that are functionally connected to the assembly spring wing rail and to the assembly base plate, and that function to generate an opposing force in connection with opening movement of the spring wing rail and an augmented force in connection with closing movement of the spring wing rail.