baber/WOPTO huggingface dataset:
Patent PT-1245674-E (PT)
Title: Nucleic acid purification
Inventor: KVEDERAS RIMANTAS
IPC: C12N15/10
Filed: 2002-03-27
Abstract: A process for purifying plasmid DNA from a nucleic acid containing sample comprising plasmid DNA and contaminants, which process comprises a step of contaminant removal, comprising:  (a) treating the sample to form a nucleic acid solution having a concentration of monovalent cations; (b) contacting the nucleic acid solution with an ultrafiltration membrane having a molecular weight exclusion limit of at least 30kDa under conditions in which substantially no gel-layer forms and in which the concentration of monovalent cations is sufficiently high for a time sufficient to remove substantially all RNA and form a retentate containing plasmid DNA; and (c) collecting the retentate.
Patent PT-1325746-E (PT)
Title: Controlled release oxycodone salt compositions
Inventor: KAIKO ROBERT FRANCIS
IPC: A61K47/44
Filed: 1992-11-25
Abstract: (A) Controlled release oxycodone formulation for oral admin. to human patients, comprises (i) 10-40mg oxycodone or its salt, the formulation providing a mean max. plasma conc. of oxycodone of 6-60 ng/ml from a mean of 2-4.5 hrs.. After admin., and a mean min. plasma conc. of 3-30 ng/ml from a mean of 10-14 hrs. after repeated admin. every 12 hrs. through steady state conditions. (ii) 10-160 mg oxycodone or its salt, the formulation providing a mean max. plasma conc. of oxycodone of 6-240 ng/ml from a mean of 2-4.5 hrs. after admin., and a mean min. plasma conc. from 3-120 ng/ml from a mean of 10-14 hrs. after repeated admin. every 12 hrs. through steady-state conditions. (B) Also claimed is a solid controlled release oral dosage form comprising (i) oxycodone or its salt in amt. of 10-160 mg; a controlled release matrix selected from hydrophilic hydrophobic polymers, digestible opt. substd. 8-50C hydrocarbons, and/or polyalkylene glycols; and a diluent; wherein the compsn. provides a mean max. plasma conc. of oxycodone of 6-240 ng/ml from a mean of 2-4.5 hrs. after admin, and mean min. plasma conc. of 3-120 ng/ml from a mean of 10-14 hrs. after repeated admin. every 12 hrs. through steady-state conditions; or (ii) an analgesically effective amt. of spheroids comprising oxycodone or its salt and either a spheronising agent or an acrylic polymer or copolymer, such that the total dosage of oxycodone in the dosage form is 10-160 mg; a film coating which controls the release of the oxycodone or its salt at a controlled rate in an aq. medium, wherein the compsn. provides an in vitro dissolution rate of the dosage form.
Patent PT-1569780-E (PT)
Inventor: THOMAS FRESER-WOLZENBURG
IPC: B29C44/34
Filed: 2003-12-02
Abstract: A method for manufacturing a foamed polyurethane molded article, that includes the steps of introducing an expandable polyurethane reactive mixture into a mold and evacuating the mold, expanding the reactive mixture expands so as to fill the mold, and exhausting gases liberated during the expanding step through one or more expansion openings disposed at one or more points of maximum height in a top mold region, each of the expansion openings being closeable by a needle valve disposed in a valve capillary. In addition the method includes sensing a temporal pressure characteristic in the valve capillary, controlling each of the one or more needle valves using the temporal pressure characteristic, so as to close the respective expansion opening in response to a pressure drop occurring when the expanding reactive mixture penetrates into the valve capillary, opening the mold, and ejecting the molded article.
Patent PT-1640601-E (PT)
Title: Intake manifold with air vessel for an internal combustion engine
Inventor: ARPERT KLAUS PETER
IPC: F02B27/02
Filed: 2004-09-28
Abstract: An intake manifold (3) for an internal combustion engine (1) having a number of cylinders (2); for each cylinder (2), the intake manifold (3) has a respective intake pipe (4) connecting the intake manifold (3) to the cylinder (2) and regulated by an intake valve (5); and the intake manifold also has an air vessel (16) having, for each intake pipe (4), a respective hollow body (17) defining an empty chamber (18), which communicates with the intake pipe (4) by means of a high-speed compensation valve (19).
Patent PT-1601387-E (PT)
Title: A new bone substitute composition
Inventor: LIDGREN LARS
IPC: A61L27/58
Filed: 2004-03-05
Abstract: An injectable bone mineral substitute material composition with the capability of being hardened in a body fluid in vivo, which comprises at least one calcium phosphate component and at least one calcium sulfate component as a dry mixture mixed with an aqueous liquid, and at least one accelerator, the at least one calcium sulfate component being particulate hardened calcium sulfate, which has a specified particle size that is in order to confer injectablity to the composition. The invention also concerns the bone mineral substitute material produced from the composition as well as methods and uses thereof.
Patent PT-1651693-E (PT)
Title: Aqueous dispersions of hydrosoluble polymerisates of ethylenically unsaturated anionic monomers, method for the production and use thereof
Inventor: CLAASSEN PETER
IPC: C08F251/00
Filed: 2004-07-17
Abstract: An aqueous dispersion of water-soluble polymers obtained by free radical polymerization of ethylenically unsaturated anionic monomers in an aqueous medium in the presence of a stabilizer, wherein the stabilizer comprises: (a) at least one water-soluble polymer selected from the group consisting of a graft polymer of vinyl acetate and/or vinyl propionate on polyethylene glycol, a polyethylene glycol blocked at one or both terminal groups with an alkyl, a carboxyl or an amino group, and a copolymer of alkyl polyalkylene glycol methacrylate and methacrylic acid; and (b) at least one water-soluble polymer selected from the group consisting of a hydrolyzed copolymer of vinyl alkyl ether and maleic anhydride in the form of free carboxyl groups or in the form of salts at least partially neutralized with one or more alkali metal hydroxides or one or more ammonium bases, a cationically modified potato starch, an anionically modified potato starch, a degraded potato starch and maltodextrin.
Patent PT-1663244-E (PT)
Title: Pteridine derivatives for the treatment of tnf-alpha-related diseases.
Inventor: WAER MARK JOZEF ALBERT
IPC: A61P39/00
Filed: 2004-09-13
Abstract: This invention relates to the use of a group of pteridine derivatives, their pharmaceutically acceptable salts, N-oxides, solvates, dihydro- and tetrahydroderivatives and enantiomers, for the manufacture of a medicament for the prevention or treatment of TNF-alpha related disorders.
Patent PT-1764890-E (PT)
Title: Suspension clamp for a low-voltage cable
Inventor: JULKUNEN SEPPO
IPC: H02G7/05
Filed: 2005-09-16
Abstract: The invention relates to a suspension clamp for a low-voltage cable, comprising a body (1) provided with a suspension loop (2) and a hook-like or C-shaped base member (3) adapted to receive a suspended cable through its open side. A clamping arm (4) is adaptable to close the base member's open side and made movable towards the base member (3) by means of a manually operated clamping mechanism (8) which includes a screw (9) provided with a tightening wing (10). The body (1) has between the suspension loop (2) and the base member (3) a slot or recess (6) for accommodating the closing clamp's first end (4a). The slot or recess (6) includes several successive adjustment grooves (7) which are dimensioned to receive the closing clamp's axle pin or pins (5) in optional grooves (7). The clamping mechanism (8) is mounted on the clamping arm's second end (4b) and provided with a spring (13) for loading the clamping arm (4) such that the axle pins (5) are biased towards retreating into the adjustment grooves (7).
Patent PT-1763423-E (PT)
Title: Reversible floating punch retainer for punch change retainer tool
Inventor: GOEDEKING LYNN VAN
IPC: B26F1/14
Filed: 2005-06-30
Abstract: A punch change retainer (8) for positioning a floating punch (74) in a retracted, disengage position and an extended, engage position. The change retainer includes a change retainer body (10) and a punch retainer receiving aperture (20) extending upwardly through the change retainer body from a bottom surface thereof A gagging member (50) is located in the change retainer body and is actuable by an actuator (14) between a retracted position distal from a nose portion (12) of the change retainer body and an extended position adjacent the nose portion of the change retainer body. A floating punch retainer (64) is receivable within the punch retainer receiving aperture, and includes an upper end positioned for engagement with the gagging member. A punch receiving hole (72) is defined in the floating punch retainer; where the punch receiving hole is adapted to be rotatably positioned about a longitudinal center line (68) of the floating punch retainer within the punch retainer receiving aperture.
Patent PT-659412-E (PT)
Inventor: FONTANA STEVEN ANTHONY
IPC: A61P25/20
Filed: 1994-12-19
Abstract: The use of 2-phenyl-3-benzoylbenzothiophenes of formula (I) and their salts to inhibit the symptoms of premenstrual syndrome (PMS) or late luteal phase dysphoric disorder (LLPDD) is new. R1, R3 = H, Me, C(O)(1-6C)alkyl or CO-Ar; Ar = opt. substd. phenyl; R2 = pyrrolidine, hexamethyleneimino or piperidino.
Patent PT-728057-E (PT)
Inventor: RAMANATH SRINIVASAN
IPC: C22C26/00
Filed: 1994-09-23
Abstract: The present invention is a metal bond comprising a filler with a Vickers hardness from about 300 kg/mm2 to about 800 kg/mm2 wherein the Vickers hardness of the filler is maintained above 300 kg/mm2 upon firing of the bond at a temperature above 700 DEG  C. for at least about 10 minutes. The present invention further is an abrasive tool comprising a metal core; an abrasive composition comprising diamond and the above metal bond, bonded to the metal core.
Patent PT-729453-E (PT)
Inventor: WITZEL TOM
IPC: C07D201/08
Filed: 1994-11-15
Abstract: PCT No. PCT/EP94/03782 Sec. 371 Date May 16, 1996 Sec. 102(e) Date May 16, 1996 PCT Filed Nov. 15, 1994 PCT Pub. No. WO95/14665 PCT Pub. Date Jun. 1, 1995Cyclic lactams are prepared by reacting amino carbonitriles with water in liquid phase in a fixed bed reactor in the presence of heterogeneous catalysts which have no soluble constituents under the reaction conditions.
Patent PT-731694-E (PT)
Inventor: GOLDENHEIM PAUL
IPC: A61K9/54
Filed: 1994-11-22
Abstract: Oral sustained release opioid formulation comprises: an opioid analgesic, a retardant material to cause the opioid analgesic to be released at a rate to provide an analgesic effect after oral admin. to a human patient for 24 hrs, the formulation when administered in humans providing an initially rapid rate of rise in the plasma conc. of the opioid characterised by providing an absorption half-life of 1-8 hrs. in the fastened state. Method for titrating human patients with a sustained release oral opioid formulation comprises: 1) administering to a human patient on a once-a-day basis a unit dose of an oral sustained release formulation comprising a dose of an opioid analgesic and a retardant material as described above, 2) monitoring pharmacokinetic and pharmacodynamic parameters elicited by the formulation in the human patient and determining whether the pharmacokinetic and/or pharmacodynamic  parameters are appropriate to treat the patient on a repeated basis, 3) titrating t he patient by adjusting the dose of the opioid analgesic administered to the patient by administering a unit dose of the sustained release opioid analgesic formulation if it is determined that the pharmacokinetic and/or the pharmacodynamic parameters are not satisfactory or maintaining the dose of the opioid analgesic in the unit dose at a previously administered amt. if the pharmacokinetic and/or pharmacodynamic parameters are deemed appropriate, 4) continuing the step 3 titration by adjusting the dose of the opioid analgesic until appropriate steady state pharmacokinetic and/or pharmacodynamic parameters are achieved in the patient, and 5) continuing the admin. of the dose of the opioid analgesic in the oral sustained release formulation on a once-a-day basis until treatment is terminated.
Patent PT-750614-E (PT)
Inventor: LEONARDI AMEDEO
IPC: A61P43/00
Filed: 1995-03-17
Abstract: PCT No. PCT/EP95/01001 Sec. 371 Date Sep. 17, 1996 Sec. 102(e) Date Sep. 17, 1996 PCT Filed Mar. 17, 1995 PCT Pub. No. WO95/25726 PCT Pub. Date Sep. 28, 1995New qunazolinyl-amino derivatives useful as  alpha 1-adrenoreceptor blockers are described. These compounds can be used as therapeutic agents for treating afflictions and diseases related to hyperactivity of the  alpha -adrenergic system, such as, for example, arterial hypertension, prostate benign hyperplasia, high intraocular pressure and hpercholesterolemia. Processes for the preparation of the above said compounds are also described.
Patent PT-758890-E (PT)
Inventor: OLESEN JES
IPC: A61P43/00
Filed: 1995-05-10
Abstract: The present invention relates to the use of a NO scavenger or an inhibitor or antagonist in the prophylactic or acute treatment of migraine or other vascular headaches in mammals including humans.
Patent PT-796153-E (PT)
Inventor: CORMACK ALEXANDER D
IPC: B07B1/48
Filed: 1995-10-31
Abstract: A tensioning member for a blade screen that permits simultaneous tensioning of a plurality of blades in a blade screen, such as for wood chip sorting. The blades may be provided with a sawtooth detail on a bottom edge to reduce the build-up of wood ribbons or fines that would otherwise occur. An elastomeric joint is also provided which allows a dual-frame blade screen to be assembled, while compensating for any phase angle error between eccentric shafts provided to agitate the wood chips by moving the screens.
Patent PT-823851-E (PT)
Inventor: ROZGA JACEK
IPC: A61F2/958
Filed: 1996-04-30
Abstract: An implantable catheter comprises a flexible elongated catheter body having an inflatable balloon positioned near its distal end. At least one distal delivery port is located distal of the balloon and at least one proximal delivery port is located proximal of the balloon. The balloon and the distal and proximal delivery ports are connected in fluid communication with individual lumens. The lumen connected to the balloon is connected to a balloon inflation port at the proximal end of the catheter. The lumens connected to the distal and proximal delivery ports are connected to distal and proximal injection ports. Preferably, the balloon inflation port and the distal and proximal injection ports are all built into an integrated port assembly adapted for implantation under the skin of a medical patient. In use, the distal end of the catheter is inserted and fed into a passageway such as a blood vessel until the balloon and delivery ports lie within a region of interest. The port assembly is then implanted under the patient's skin. Once in place, the balloon can be inflated to occlude the flow of fluid through the passageway, and therapeutic agents can be delivered either distal or proximal of the balloon by injection into the appropriate injection port. It is believed that the catheter is particularly suited to the delivery of hepatocytes and an anticoagulant during a course of cell therapy directed to a patient's liver.
Patent PT-810022-E (PT)
Inventor: GUSSGEN OLAF
IPC: B01D53/46
Filed: 1997-05-16
Abstract: The plant for a wet process to clean aluminium dust from process air passes the air into a washer through a number of pipes into which a sodium hydroxide solution is sprayed. The reaction product, sodium aluminate, is collected in the base of the washer whilst clean air is drawn off the top by a fan. Also claimed is the cleaning process using the above plant.
Patent PT-867179-E (PT)
Inventor: MELAMED ELDAD
IPC: A61K31/216
Filed: 1993-12-24
Abstract: A composition which comprises a pharmaceutically acceptable carrier and an active ingredient, such active ingredient comprising L-DOPA ethyl ester in an amount which is at least 97%, by weight, of the active ingredient, and L-DOPA in an amount which is less than 1% by weight of such active ingredient is provided by this invention. This invention also provides a process for preparing such a composition. Further, this invention provides a method of treating a patient suffering from Parkinson's disease which comprises administering to a patient a pharmaceutical composition comprising a therapeutically effective amount of L-DOPA ethyl ester and a pharmaceutically acceptable carrier.
Patent PT-1036297-E (PT)
Inventor: GUEN LOIC LE
IPC: B60K15/01
Filed: 1998-11-25
Abstract: The invention provides an air-liquid heat exchanger for a motor vehicle fluid-flow circuit (2, 3), the heat exchanger comprising a plurality of tubes (4) extending between two fixing and distribution blocks (5, 6) to which the ends of the tubes are coupled, each of said two blocks comprising:a face (10, 13) facing the other block and carrying internal coupling members (15) for coupling the corresponding ends of the tubes (4) to the block in question;an internal distribution channel (17) interconnecting the internal coupling members (15); andan external coupling member (19) for coupling the block in question and its internal distribution channel (17) to the fluid-flow circuit (2, 3) of the vehicle. At least one (5) of the two blocks has at least one ventilation nozzle (23) passing therethrough between its face (10) carrying the internal coupling members (15) for coupling tubes (5) to said block, and its opposite face (9).
Patent PT-1046978-E (PT)
Inventor: HUSSEIN SALLAM
IPC: G06F1/16
Filed: 1999-08-04
Abstract: Each module (1) is constructed as a closed compartment in to which computer components fit, with at least one sidewall (2) containing a heat sink. Each module contains part(s) of a conventional computer such as storage, processor, input and output devices, activation systems and peripheral connections. The activation systems include audio, pen, eye tracking, head, arm and brain wave activation. The modules connect together using a mechanical clasp (4,5) and electrical connectors for the parts in the module.
Patent PT-994772-E (PT)
Inventor: BOIS HENRI GEORGES
IPC: B31B19/90
Filed: 1999-05-04
Abstract: A method for automatically making bags equipped with matching closure profiles comprising the steps of: unwinding a supply of at least a film for forming the bag walls; unwinding a supply of closure assembly comprising a W-shaped support sheet, constituting an inner U-shaped tear band provided on its inner surface opposite respectively the matching closure profiles, and the external lateral webs extending beyond the closure profiles and the U-shaped inner band, the closure assembly being further pre-equipped with a series of sliders actuating the closure profiles distributed over the length of the unwinding closure assembly; and fixing the resulting closure assembly via the external lateral webs on the film forming the bag walls.
Patent PT-1096934-E (PT)
Inventor: FORD CHARLES W
IPC: A61K9/06
Filed: 1999-07-07
Abstract: The present invention involves a method of treating an ophthalmic infection in a useful warm blooded mammal who is in need of such treatment which comprises topical administration of an ophthalmologically effective amount of an OXAZOLIDINONE.
Patent PT-1098893-E (PT)
Inventor: JEAN-JACQUES BERTHELON DR
IPC: A61K31/4035
Filed: 1999-07-09
Abstract: The present invention relates to cyclic compounds which are of the class of compounds of formula I wherein X and Y represent an oxygen atom and to processes for preparing such compounds. The compounds are useful in the treatment of dyslipidemia, atherosclerosis, and diabetes.
Patent PT-1139728-E (PT)
Inventor: HEBRANK JOHN H
IPC: G01N33/08
Filed: 1999-12-23
Abstract: A method of injecting a plurality of bird eggs comprises: (a) orienting a plurality of avian eggs in a predetermined position; (b) forming an opening in the shell of each of the eggs; (c) extending an elongate delivery device through each of the openings and into the eggs, each of the delivery devices comprising a detector and an injection needle, with the injection needle having a lumen formed therein; (d) detecting with the detector information from the interior of each of the plurality of eggs; and (e) injecting a substance into each of the plurality of eggs through the lumen of said injection needle. The detected information can be used for a variety of purposes, including adjusting the depth of penetration of the injection needle to more precisely control the location of the injection, identifying the gender of the eggs for subsequent sorting of the eggs, distinguishing viable from non-viable eggs, etc. When used for controlling depth penetration, the method positions the needle tip for any purpose, including withdrawing biological material as well as injecting substances. Apparatus, particularly high-speed apparatus, for carrying out the method is also disclosed.
Patent SG-29295-G (SG)
Title: Apparatus for ironing laundry
Inventor: JENSEN JORN MUNCK
IPC: D06F67/08
Filed: 1995-02-20
Abstract: An apparatus for ironing laundry, said apparatus comprising at least one semi-circular open dished bed (1), provided with a double wall with feed (5) and outlet (6) opening for passage of a heating medium, such as steam, and a roll (2) rotatably driven in each dished bed (1), wherein the outlet opening (6) of a dished bed (1) is placed in direct connection to the feed opening (5) of the following dished bed (1), what requires a high flowspeed, preventing eventual condensation of the heat medium in the flow ducts in the dished bed wall, and so preventing an uneven temperature distribution in the inner wall of the dished bed.
Patent SG-23421-G (SG)
Title: Bimetallic catalyst
IPC: B01J27/135
Filed: 1987-08-03
Abstract: Process of preparing a bimetallic catalyst comprising     a) applying a titanium compound to an inorganic carrier; b) applying, simultaneously with or after applying the titanium compound, to the inorganic carrier at least one additive which is selected from the group consisting of a bromine compound, a fluorine compound and an iodine compound; c) applying, simultaneously with or after applying the additive, to the inorganic carrier a vanadium compound;   d) drying the carrier; and e) subjecting the carrier to a heat treatment at a temperature between 200  DEG C and 800  DEG C. c
Patent IE-890046-L (IE)
Title: Producing green diamond
IPC: C01B31/06
Filed: 1989-01-09
Abstract: PURPOSE: To obtain green diamond, containing only the H2 center and having bright color and transparency, by irradiating specific bright yellow Ib type diamond with electron rays and heat-treating the irradiated diamond under a vacuum. CONSTITUTION: Bright yellow Ib type diamond having 5×1016W3×1019atoms/cm3 nitrogen content in crystals is irradiated with electron rays at =1×1018electrons/ cm2 at 2W4MeV accelerated voltage and then heat-treated at 1500W1800°C under a vacuum of =10-3Torr for =10hr. Alternatively, heat treatment is carried out at =6000°C under a superhigh pressure of =3.0GPa for =10hr. Thereby the aimed green diamond having 5×1016W3×1019atoms/cm3, 0.3W6cm-1 absorption coefficient at 800nm wavelength of the H2 center, 0.05W1.5cm-1 absorption coefficient at 500nm wavelength of Ib type nitrogen and =0.2cm-1 absorption coefficient of other absorptions within the visible region is obtained[JP1183409A]
Patent IE-36148-L (IE)
Title: Making edge-plates for receptacles
IPC: B31B50/70
Filed: 1972-03-08
Abstract: This disclosure has to do with the forming of fittings for wood containers and the like from continuously fed strip material. Mechanism is provided for performing various stamping and working operations on this strip material in a manner to keep pace with the movement of the strip material and after each work operation is performed on the strip material, the tool performing the work operation is returned to its initial position and subsequent performance of a further work operation.
[US3797428A]