baber/WOPTO huggingface dataset:
Patent CA-2378933-A1 (CA)
Title: Iterative probe design and detailed expression profiling with flexible in-situ synthesis arrays
Inventor: FRIEND STEPHEN H
IPC: G16B25/20
Filed: 2000-07-14
Abstract: Methods and compositions are provided that are useful for detecting and reporting a plurality of different target polynucleotide sequences in a sample, such as polynucleotides corresponding to a plurality of different genes expressed by a cell or cells. In particular, the invention provides methods for screening a plurality of candidate polynucleotide probes to evaluate both the sensitivity and the specificity with which each candidate probe hybridizes to a target polynucleotide sequence. Candidate polynucleotide probes can then be ranked according to both their sensitivity and specificity, and probes that have optimal sensitivity and specificity for a target polynucleotide sequence can be selected. In one embodiment, polynucleotide probes can be selected according to the methods described herein to prepare "screening chips" wherein a large number of target polynucleotide sequences are detected using a single microarray have a few (e.g., 1-5) probes for each target polynucleotide sequence. In a particularly preferred embodiment, the invention provides a screening chip that can detect genetic transcripts from the entire genome of an organism. In an alternative embodiment, polynucleotide probes can be selected according to the methods described herein to prepare "signature chips" to more accurately detect certain selected "signature genes"  using several polynucleotide probes (e.g., 10-20) for each signature gene. The invention additionally provides microarrays containing polynucleotide probes for a large number of genes expressed by a cell or organism. Further, methods for detecting a plurality of polynucleotide molecules, including a large number of genes expressed by a cell or organism, are also provided.
Patent CA-2379285-A1 (CA)
Inventor: ASO OSAMU
IPC: H04B10/50
Filed: 2002-03-27
Abstract: A multi-frequency light producing method and apparatus multiplies the number of optical channels present in an incident wavelength division multiplexed (WDM) signal light source by four-wave mixing (FWM) the WDM signal with at least one pump lightwave at least one time. By FWM the WDM light and a pump lightwave multiple times, wherein each FWM process is executed with a pump lightwave having a different frequency, either in series or parallel, the number of optical channels produced as a result of FWM  effectively increases the number of optical channels present in addition to those from the WDM  signal. The light producing method and apparatus can be employed in a telecommunications system as an inexpensive light source producing a plurality of optical frequencies.
Patent CA-2381663-A1 (CA)
Title: Toilet reservoir water discharge control device
Inventor: WING DONALD W
IPC: E03D1/14
Filed: 2002-04-18
Abstract: In a tool for controlling the escape of water from a toilet reservoir it is known to have a rod float is guided through a bracket attached to the overflow vent and controls the up and down motion of the ball cock that when down shuts off the water escape.        In this invention a coil spring is affixed to the rod between the ball cock and the guide bracket.        In contrast to the ball cock floating down on top of released water the ball cock is projected through the. water to the escape aperture immediately upon release of the toilet flush handle, prohibiting the escape of unnecessary waste water.
Patent CA-2384558-A1 (CA)
Title: High temperature super-conducting coils supported by an iron core rotor
Inventor: LASKARIS EVANGELOS TRIFON
IPC: H02K3/46
Filed: 2002-05-02
Abstract: A rotor for a synchronous machine is disclosed comprising: a cylindrical magnetic solid rotor core; a race-track super-conducting coil winding extending around the rotor core; a coil support extending through the core and attaching to opposite long sides of the coil winding, and a pair of end shafts extending axially from said core and attached to the core.
Patent CA-2386084-A1 (CA)
Inventor: BECKER ECKHARD
IPC: B65B9/02
Filed: 2001-08-02
Abstract: The invention relates to a method and a device for packaging a block of material consisting of a compressible material. According to said method, a block of material is compressed by bringing together two compression units (120, 122) and in its compressed state is either pushed against a stretched film web and enveloped by the same, or alternatively the film web is pushed against the block of material and pulled over the latter. The ends of the fi lm web are welded together.
Patent CA-2386657-A1 (CA)
Inventor: CONEY STUART SHEPPARD
IPC: C03C17/00
Filed: 2000-10-05
Abstract: A glass coating hood (10) includes a housing (12) with conveyor belts (14) running through it and loops of high speed air flow carrying entrained glass coating composition for deposition on glass containers (16) riding the belts.  Adjacent to the belts (14) are hollow tubes (116, 118) cooled by coolant flowing therein. Behind the coolant tubes (116, 118) are sets of vertical vents (112) and control orifice panels (120). Vertically adjustable side walls (130, 132, 134, 136) enable the receiving side of the conveyor belt (14) to be slightly higher than the issuing side to capture the oxide laden air. Baffles (148, 154, 156) formed in the housing (12) above the conveyor belts (14) create a dead space (140) that traps coating-free air injected from above to prevent oxide laden air from up-welling from below.
Patent CA-2387860-A1 (CA)
Inventor: OTTENBERG MATTHIAS J
IPC: G01N21/49
Filed: 2000-10-20
Abstract: A flow cytometry apparatus (1) and methods to process information incident to particles or cells entrained in a sheath fluid stream allowing assessment, differentiation, assignment, and separation of such particles or cells even at high rates of speed. A first signal processor (18) individually or in combination with at least one additional signal processor (17) for applying compensation transformation on data from a signal (15). Compensation transformation can involve complex operations on data from at least one signal (15) to compensate for one or numerous operating parameters. Compensated parameters can be returned to the first signal processor (18) for providing information upon which to define and differential particles (3) from on another.
Patent CA-2388343-A1 (CA)
Inventor: CLAPP WADE D
IPC: A61P25/28
Filed: 2000-11-10
Abstract: La présente invention concerne une méthode pour identifier les inhibiteurs de Raf, MEK, protéine ERK1, protéine ERK2, phosphatidylinositol triphosphate kinase (P13K), protéine PAK2, protéine PAK3, Rac, CDC42, protéine PAK1, protéine kinase B (PKB), Akt, de c-protéine JNK, ou du couplage parasite entre P13-K et le trajet Ras-Raf-MEK-ERK, utilisés pour traiter les troubles tels que la neurofibromatose de type 1, ou au moins un de ses signes cliniques.
Patent CA-2389978-A1 (CA)
Title: System and method for pushing encrypted information between a host system and a mobile data communication device
Inventor: LAZARIDIS MIHAL
IPC: G06Q10/10
Filed: 2002-06-10
Abstract: A system and method for pushing information from a host system to a mobile data communication device upon sensing a triggering event is disclosed. A redirector program operating at the host system enables a user to continuously redirect certain user-selected data items from the host system to the user's mobile data communication device upon detecting that one or more user-defined triggering events has occurred. The redirector program operates in connection with event-generating applications and repackaging systems at the host system to configure and detect a particular user-defined event, and then to encrypt and repackage the user-selected data items in an electronic wrapper prior to pushing the data items to the mobile device.
Patent CA-2391027-A1 (CA)
Inventor: MARCHAND RENE
IPC: D03D3/04
Filed: 2002-06-19
Abstract: A press felt that can have a reduced tendency to fray at the seam cut includes: a paper side batt layer; a machine side batt layer; and a base fabric layer sandwiches between the paper side batt layer and the machine side batt layer.  The base fabric layer comprises a first fabric and a second fabric. The first fabric includes machine direction yarns and cross machine direction yarns interwoven with the machine direction yarns. The first fabric has first and second ends with loops, wherein the loops of the first end are interdigitated with the loops of the second end, and the loops of said first and second ends receive a pin to form the first fabric into an endless belt having a seam. The second fabric is formed into an endless belt overlying the first fabric and includes machine direction yarns and cross machine direction yarns interwoven with the machine direction yarns, wherein the machine direction yarns are formed of a low melt material. In this configuration, the low melt machine direction yarns of the second fabric may have a reduced tendency to fray at the seam cut during prolonged operation.
Patent CA-2395392-A1 (CA)
Inventor: DANG VU A
IPC: C08F255/02
Filed: 2001-10-26
Abstract: L'invention porte sur la fabrication de copolymères greffés présentant des chaînes latérales à faible masse moléculaire, comprenant les étapes suivantes : (1) irradiation, sans oxygène, d'un polypropylène ; (2) addition d'une quantité contrôlée d'oxygène dans le matériau polymère irradié afin d'exposer celui-ci à une quantité d'oxygène supérieure à 0.004 % mais inférieure à 15 % en volume, à une température comprise entre 40 ·C et 140 ·C, dans le but d'obtenir un polypropylène oxydé contenant plus d'1 millimole de peroxyde totale par kilogramme de polypropylène ; (3) éventuellement chauffage de polypropylène oxydé dans des conditions de non-oxydation, à une température d'au moins 80 ·C mais en-dessous du seuil de ramollissement du polymère ; (4) traitement du polypropylène oxydé dans des conditions de non-oxydation avec au moins un monomère de greffage qui peut être polymérisé par des radicaux libres, en présence d'au moins un additif, cela afin de contrôler la masse moléculaire des chaînes latérales du monomère de greffage polymérisé choisi parmi : (a) au moins un agent inhibiteur de polymérisation dérivé d'hydroxylamine ; et (b) au moins un composé aromatique ou aliphatique substitué par halogène, nitro ou thio, ou un dérivé de phosphine aromatique ou aliphatique ; (5) désactivation des radicaux libres résiduels dans le polypropylène greffé, et retrait, du matériau, de tout monomère de vinyle intact.
Patent CA-2395825-A1 (CA)
Inventor: LINDEN JOHAN
IPC: E21B17/042
Filed: 2001-02-13
Abstract: The present invention relates to a martensitic, corrosion resistant steel for rock drilling with properties adjusted essentially with regard to resistance against corrosion fatigue. This has been obtained in that an elongated element for percussive rock drilling which includes at least a thread and a flush channel has been made in a corrosion resistant steel with a mainly martensitic structure.
Patent CA-2399059-A1 (CA)
Inventor: GILL PETER JOHN
IPC: F01L1/22
Filed: 2001-01-31
Abstract: L'invention concerne un dispositif de réglage de jeu de soupape automatique, comprenant un logement femelle fileté (1) et une vis mâle filetée (3) s'étendant dans le logement. Le filetage (4) de la vis (3) est complémentaire au filetage interne (2) du logement et s'ajuste à l'intérieur du logement avec un jeu axial prédéterminé. Le filetage possède une forme trapézoïdale, symétrique en section transversale axiale et présentant une résistance de frottement de même force contre le mouvement dans les deux directions axiales. Les angles de pression, l'angle d'hélice et le nombre d'entrées de filet sont sélectionnés de manière à assurer que la vis puisse tourner et sortir axialement du logement sous l'effet unique d'une force axiale appliquée sur son extrémité, dans le logement. L'extrémité émergente (7) de la vis est conçue pour coopérer avec un élément adjacent exerçant une force de résistance de frottement de sens opposé à la force de rotation de la vis.
Patent CA-2399209-A1 (CA)
Title: Process for preparation of indolopyrrolocarbazole derivative, intermediates in the preparation and process for preparation of the intermediates
Inventor: NAKANO FUMIO
IPC: C07H19/044
Filed: 2001-02-22
Abstract: This invention relates to a process for preparation of an indolopyrrolocarbazole derivative [I] by treating a compound[V]  with a base in an inert solvent to prepare a compound [IV], reacting the obtained compound [IV] with a compound [III] to prepare a compound [II] and then removing the protective groups of the compound [II], the preparation intermediates compound [II], compound [III] and compound [IV], and processes for preparation of the compound [III].     (see formula V) (see formula IV) (see formula I) (see formula III) (see formula II) wherein Y1 represents a hydrogen atom, an alkyl group having 1 to 4 carbon atoms, a phenyl group, a benzyloxymethyl group or an aralkyl group, R1, R2, R3, R4, R5 and R6 may be the same or different and each represent a protective group of a hydroxyl group, R7 and R8 may be the same or different and each represent a hydrogen atom or a protective group of a hydroxyl group, and X represents an acid molecule.     This invention provides a safe and easy industrial preparation process of the indolopyrrolocarbazole derivative [I] useful as an antitumor agent.
Patent CA-2399302-A1 (CA)
Inventor: SOLIOZ ROGER
IPC: G07C9/00
Filed: 2001-01-16
Abstract: Passwords consisting in symbols selected from a third set of third symbols, whereof a first set constitutes a subset of first symbols, can be created from a data structure. The invention concerns a method for obtaining said structure comprising the following steps: preparing a second set of at least two second symbols; creating a first number of first lists of first symbols each contained in a third list consisting of third symbols; creating a second list of second symbols, each symbol appearing only once in said list; associating a first list with each symbol of a second list; associating a second symbol with each symbol of the first lists. With the use of said structure (27), it is possible to create numerous pseudo-random passwords by using a code comprising a second symbol, a sub-code of at least a first symbol and a path (51) for reading the symbols in the third lists of the structure from the first symbol found by using the second symbol and the sub-code.
Patent CA-2400545-A1 (CA)
Title: Method of displaying three dimensional vector orientations on a two dimensional surface
Inventor: KOMARECHKA ROBERT GERALD
IPC: G01V3/38
Filed: 2002-08-30
Abstract: A method for generating, displaying and manipulating the orientation of three- dimensional vectors on a two dimensional surface for visualization, statistical analysis and correlation. The method involves collecting vector data, transforming each vector into spherical co-ordinates, then assigning, a unique colour related to a position on a spherical colour model. A two- dimensional raster image filled with this unique colour is centred at the point of measurement for each vector orientation as obtained from calculations or instrumentation. A user may also discriminate the location of specific orientations as well as the ability to define an enhanced full colour gamut gradation for a specific range of orientation. This rendering of colour coded vector orientation enables easier understanding by the viewer of large data sets.
Patent CA-2401916-A1 (CA)
Title: Recombinant anti-tumor rnase
Inventor: RYBAK SUSANNA M
IPC: A61P35/00
Filed: 1999-03-26
Abstract: This invention provides for new recombinant proteins linked to an antibody directed against a cell surface antigen on a cancerous B cell, to form cytotoxic fusion proteins.  These proteins are more active than ribonucleases currently available even though the proteins of this invention lack an N-terminal pyroglutamic acid, which has been found to be necessary for ribonucleolytic activity. Because these proteins are recombinant proteins, mutations which increase cytoxicity can be engineered.
Patent CA-2402584-A1 (CA)
Title: Dosing form for a polymer support, use of said dosing form in organic chemical synthesis and method for production of said dosing form
Inventor: EGESKOV HOLM JANNIE
IPC: C07C217/60
Filed: 2001-03-16
Abstract: A dosing form for a polymer support for organic chemical synthesis in a solvent medium comprising a fixed weight amount of beads of a polymer containing functional groups, which polymer is insoluble in the solvent for the intended synthesis, is provided as compressed tablets of essentially equal weight and composition wherein the polymer beads are essentially intact and are released as such when the tablets are disintegrated in said solvent. Use of the dosing form is made in conventional synthesis, in parallel synthesis, in split and mix synthesis and/or combinatorial chemistry. In a method for producing the dosing form, beads of a polymer having functional groups are compressed into tablets after pre-treatment with an aprotic organic solvent.
Patent CA-2403346-A1 (CA)
Title: Scalpel blade having high sharpness and toughness
Inventor: MECKEL NATHAN K
IPC: B26B9/00
Filed: 2001-03-14
Abstract: A scalpel blade (20) is made by depositing a coating (32) onto a tapered region (26) of a substrate (22) which is tapered with an included angle of from about 10 to about 25 degrees to an edge. The substrate (22) is made of surgical-grade stainless steel hardened to a Rockwell C hardness of at least 54 and then annealed to a Rockwell C hardness of from about 46 to less than about 53. The coating (32) overlying the tapered region (26) has a thickness of from about 0.1 to about 2.5 micrometers and includes a first coating layer (34) of a first metal, and a second coating layer (36) overlying the first coating layer (34). The first coating layer (34) is preferably zirconium or a zirconium-base alloy, and the second coating layer (36) is preferably zirconium nitride. The edge may be atomically sharpened by applying a large negative voltage to the substrate (22) relative to the deposition source while a portion of the thickness of the second coating layer (36) is being deposited.
Patent CA-2404047-A1 (CA)
Title: Packet network transfer apparatus, packet network transfer system and packet network transfer method
Inventor: MIYAMOTO REI
IPC: H04L47/2491
Filed: 2002-09-18
Abstract: An identifier distinguishing unit 14 distinguishes what the identifier contained in a packet is. A VC search processing unit 13 searches the identifier/VC management table 12 using that identifier as the search character sequence. A VC selecting unit 15 selects an ATM VC for use in transmission on the basis of the ID information on ATM VCs resulting from the search. A cell formation processing unit 16 subjects the packet to ATM self format conversion processing. A frame formation processing unit 24 regenerates individual packets from packet information. A VC distinguishing unit 25 distinguishes the ID information on ATM VCs pertaining to each individual packet.    An identifier search processing unit 23 searches the VC/identifier management table 22 using the ID information on ATM VCs as the search character sequence. An identifier assigning unit 26 assigns the identifier resulting from the search to the packet, and supplies that packet. This makes it possible to comprehensively manage packets transferred across a plurality of packet networks having different identifier management policies.
Patent CA-2404642-A1 (CA)
Title: Recess arrangement for blister pack
Inventor: NOTTINGHAM JOHN R
IPC: B65D75/36
Filed: 2001-03-21
Abstract: A package for an article (10) incorporating an on/off switch (16) having a momentary-on position and a continu-ously-on position is disclosed. The package includes a cover (24) such as a blister-type cover (24) at least partially enclosing the article (10), and a recess arrangement formed in the cover (24) proximate the switch (16). The recess arrangement prevents the switch (16) from being slid into the continuously-on position while permitting the switch to be depressed into a momentary-on position. The recess arrangement includes a first recess (26) positioned directly over the switch (16), and a second recess (30) positioned directly adjacent the switch (16).
Patent CA-2404703-A1 (CA)
Title: Novel crystal form of pyrrolidylthiocarbapenem derivative
Inventor: TAKAHIRA MASAYUKI
IPC: F04D29/00
Filed: 2001-03-30
Abstract: A novel crystal form of a pyrrolidylthiocarbapenem derivative which has excellent stability. It is a crystal of (+)-(4R,5S,6S)-6-[(1R)-1-hydroxyethy l]- 4-methyl-7-oxo-3[[(3S,5S)-5-(sulfamoylaminomethyl)pyrrolidin-3-yl]thio]-1- azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid which, in X-ray powder diffractometry, gives a diffraction pattern preferably having main peaks at diffraction angles (2.theta.) of 13.04, 14.98, 15.88, 16.62, 20.62, 21.06, 22.18, 23.90, 26.08, 28.22, and 28.98 degrees.
Patent CA-2407378-A1 (CA)
Inventor: TATSUMISAGO MASAHIRO
IPC: G02B1/10
Filed: 2002-02-22
Abstract: A method for preparing an article having a predetermined shape wherein a sol-gel material is disposed in a film form between a substrate and a mold being closely contacted with both of them and then is heated, to thereby prepare an article having the substrate and, covering the surface thereof, a gelled film having a surface of a shape obtained by reversing the surface shape of the mold, characterized in that the sol-gel material comprises a metal compound represented by M1Xm, a hydrolyzed product thereof or a hydrolyzed and polycondensed product thereof and a metal compound represented by R1M2Yn, a hydrolyzed product thereof or a hydrolyzed and polycondensed product thereof, wherein at least one of M1and M2 is a metal atom of Ti, Zr, Al, Ge, Sn or Sb, and the above specified metal atom accounts for at least 10 atom % of the sum of M1 and M2.
Patent CA-2416325-A1 (CA)
Inventor: BAUDIN GISELE
IPC: C09D4/06
Filed: 2001-08-07
Abstract: L'invention concerne des composés des formules (Ia), (Ib) et (Ic), dans lesquelles R, R¿1? et R¿2? sont, par exemple, phényle, naphtyle, anthracyle, phénanthryle ou un radical hétérocyclique. Ces composés conviennent comme photoamorceurs qui s'accumulent à la surface de revêtements.
Patent CA-2416894-A1 (CA)
Inventor: BARANSKI JOHN R
IPC: C08F110/14
Filed: 2001-08-08
Abstract: A liquid polyalphaolefin homo- or copolymer, preferably 1-decene, which is substantially amorphous is obtained by a polymerization process employing hydrogen and a particular type of metallocene catalyst. Additionally, liquid  polyalphaolefin homo- or copolymer containing from 2 to about 12 carbon carb on atoms possess a unique combination of properties, i.e., low molecular weight  (Mw), low polydispersity index (Mx/Mn), controllable kinematic viscosity (Kv100), low Iodine Number (I2) and low glass transition temperature (Tg) an d are substantially amorphous. The liquid polyalphaolefin homo- or copolymers provided herein are useful for manufacturing a variety of products including  lubricating oils in which the polyalphaolefin functions as a viscosity modifier.