baber/WOPTO huggingface dataset:
Patent AU-2006236489-C1 (AU)
Title: Elimination of heterogeneous or mixed cell population in tumors
Inventor: ERICKSON HANS K
IPC: C12N5/09
Filed: 2006-04-14
Granted: 2012-04-12
Abstract: Methods of killing or inhibiting tumors comprising of heterogeneous or mixed cell populations is described. The killing or inhibition of tumors is achieved by selectively targeting a unique ligand suspected of being expressed on a particular cell population to also kill a cell population lacking the unique ligand. These conjugates have therapeutic use as they are delivered to a specific cell population to kill these cells and the cytotoxic drug is released to kill non-targeted cells, thereby eliminating the tumor.
Patent AU-2012233313-C1 (AU)
Title: Method for altering plasma retention and immunogenicity of antigen-binding molecule
Inventor: IGAWA TOMOYUKI
IPC: C12P21/08
Filed: 2012-03-30
Granted: 2017-08-03
Abstract: The present invention involves the discovery that by modifying the Fc region of an antigen-binding molecule to an Fc region in which a heterocomplex containing a bimolecular FcRn and four activating Fcγ receptors does not form in the neutral pH range, pharmacokinetics improve due to the antigen-binding molecule, and immune response decreases due to the antigen-binding molecule. In addition, the present invention resulted in the discovery of a method for manufacturing antigen-binding molecules having the abovementioned characteristics, and also resulted in the discovery that when a drug composition, which contains such antigen-binding molecules or antigen-binding molecules manufactured according to the manufacturing method of the present invention as an active ingredient, is administered, the antigen-binding molecules have excellent characteristics, such as improving pharmacokinetics and decreasing immune response by a living organism that has been administered the drug, compared to antigen-binding molecules of the prior art.
Patent AU-2013255013-C1 (AU)
Title: Conducting device and socket
Inventor: LIU JIE
IPC: H01R13/02
Filed: 2013-04-01
Granted: 2016-01-07
Abstract: A conducting device and a socket are disclosed. The conducting device and the socket with stable electrical-connection ability are provided. Said socket includes a socket body (5), the conducting device arranged in an accommodating slot (7) of said socket body (5), and an ending cap (6) arranged on said socket body (5). Said conducting device includes a movable spring plate (1), a stationary spring plate (2) and a reset spring member (3). Said movable spring plate (1) is rotatablely connected with said stationary spring plate (2). The reset spring member (3) is located in the outer side of said movable spring plate (1) and contacts with said movable spring plate (1). An inserting slot (4) is formed between said movable spring plate (1) and said stationary spring plate (2). The width of said inserting slot (4) is gradually decreased from inner part to outer part. Said ending cap (6) blocks said reset spring member (3) and is adaptive with said socket body (5). The present invention can be widely used in the field of electrical connection.
Patent AU-2013299562-C1 (AU)
Title: Shockwave valvuloplasty with multiple balloons
Inventor: ADAMS JOHN
IPC: A61B17/22
Filed: 2013-08-08
Granted: 2017-11-30
Abstract: Described herein are shock wave devices and methods for the treatment of calcified heart valves. One variation of a shock wave device includes three balloons that are each sized and shaped to fit within a concave portion of a valve cusp when inflated with a liquid and a shock wave source within each of the three balloons. Each balloon is separately and/or independently inflatable, and each shock wave source is separately and/or independently controllable. Methods of treating calcified heart valves using a shock wave device can include advancing a shock wave device having one or more balloons and a shock wave source in each of the balloons to contact a heart valve, inflating the one or more balloons with a liquid such that the balloon is seated within a concave portion of a valve cusp, and activating the shock wave source.
Patent RU-2177178-C1 (RU)
Title: Device for determining probability of airborne target detection by search party
Inventor: MAKARYCHEV A V
IPC: G01S5/00
Filed: 2000-06-02
Granted: 2001-12-20
Abstract: FIELD: computer engineering. SUBSTANCE: device designed for selecting best ways of searching airborne targets has multipliers, dividers, subtracters, square-root computer, and initial parameters setting unit. EFFECT: enhanced accuracy. 3 dwg
Patent RU-2179528-C1 (RU)
Title: Method of processing of sphene concentrate
Inventor: MASLOVA M V
IPC: C22B3/08
Filed: 2000-07-05
Granted: 2002-02-20
Abstract: FIELD: chemical technology of inorganic materials, more particularly manufacture of paper, plastic materials and paintwork materials. SUBSTANCE: concentrate is decomposed with sulfuric acid solution having concentration of 500-650 g/l of H 2 SO 4  under boiling conditions till concentrate is decomposed to 70-80% with respect to TiO 2 . Solid calcium-silicate residue is separated by filtration. Silicon-containing solution in amount of 20-40% SiO 2  with respect of TiO 2  in solution is introduced into titanium-containing solution. Titanium-containing product in pigment composition form is isolated by thermohydrolysis. Solid residue is treated with aluminium phosphate in amount of 1-5% Al 2 O 3  with respect to weight of residue to prepare calcium-silicate pigment filler. Silicon-containing solution is filtrate resulting from decomposition of sulfuric with sulfuric acid having concentration of 200-250 g/l of H 2 SO 4  at S:L ratio of 1:5. The resulting products have high paint and technical characteristics which are useful paintwork materials used for various purposes. EFFECT: increased recovery of titanium from sphene concentrate into final products up to 98% and greater safety of process due to lowering sulfuric acid concentration by 2 times due decomposition temperature by 20-40 C. 2 cl, 3 ex
Patent RU-2180584-C1 (RU)
Title: Cerebroprotecting agent and method of its preparing
Inventor: KHAZANOV V A
IPC: B01D11/04
Filed: 2000-10-11
Granted: 2002-03-20
Abstract: FIELD: medicine, phytotherapy, pharmacy. SUBSTANCE: invention relates to development of cerebroprotecting agent of vegetable origin eliciting an antihypoxic activity and used for prophylaxis of states accompanying with hypoxia. Invention proposes the cerebroprotecting agent including all species of crowberry extract. Extract is prepared by three-stage extractions with chloroform in the ratio raw : extractant = 1:10, then with acetone in the ratio extract : extractant = 1:10 and then with hexane in the ratio extract : extractant = 1:5. Invention proposes also method of cerebroprotecting agent preparing. The proposed cerebroprotecting agent shows an antihypoxic activity in the range of large doses - up to 200 mg/kg. EFFECT: improved method of preparing, valuable medicinal property, low adverse effects, low toxicity. 5 cl, 4 tbl, 13 ex
Patent RU-2176399-C1 (RU)
Inventor: PAKHOMOV V M
IPC: G01S13/44
Filed: 2000-10-30
Granted: 2001-11-27
Abstract: FIELD: radiolocation engineering. SUBSTANCE: device has the first and the second phase manipulators, the first adder, high frequency amplifier, mixer, linear amplifier of intermediate frequency, demodulation unit, integration unit, unit for selecting azimuth error signal, unit for shaping range tracking signal and code generator. The third phase manipulator, the first and the second phase rotation unit, the second adder and unit for selecting angular location system error signal additionally introduced into the design are connected to each other in known way. EFFECT: high accuracy and improved noise immunity in following targets. 8 dwg
Patent RU-2192571-C1 (RU)
Inventor: LEVIT M Z
IPC: F16D69/02
Filed: 2001-02-26
Granted: 2002-11-10
Abstract: FIELD: machine engineering, namely friction discs. SUBSTANCE: disc includes frictional cover plates made of composite material. On friction surface of frictional cover plates there are grooves made in limits of working thickness of cover plates fixed to metallic carcass along outer contour of which there are alternating holes and recesses. Grooves of cover plates are arranged in zones of recesses of carcass. EFFECT: lowered possibility for breaking disc by action of centrifugal loads, increased working angular velocity values due to reduced mass of carcass also providing improved reinforcement of cover plates in groove zones. 1 dwg
Patent RU-2189980-C1 (RU)
Title: Method of purification of tocopherol acetate synthesized by organic synthesis from organic impurities
Inventor: NADTOCHIJ M A
IPC: C07D311/72
Filed: 2001-03-15
Granted: 2002-09-27
Abstract: FIELD: chemical technology, vitamins. SUBSTANCE: invention relates to the improved method of purification of tocopherol acetate synthesized by chemical synthesis from organic impurities. Invention describes a method of purification of tocopherol acetate from organic impurities that involves purification by selective extraction of impurities with carbon-containing extractant. Ethyl alcohol in concentration 90%, not less, per a volume unit of extractant is used as an extractant and the process of purification is carried out at temperature in the range from 20 C to +30 C. EFFECT: improved method of purification, enhanced output of process of purification by tocopherol acetate and extractant. 2 ex
Patent RU-2187336-C1 (RU)
Title: Method of producing preparation based on strontium-89
Inventor: KAJURIN O JU
IPC: A61K41/17
Filed: 2001-06-01
Granted: 2002-08-20
Abstract: FIELD: medicine, pharmaceutical technology. SUBSTANCE: invention relates to medicinal preparations containing radioactive substances. Method involves irradiation of yttrium oxide by fast neutrons, dissolving the obtained mixture of isotopes in acid and chemical isolation of the end product from solution with acidity from 1.5 to 4.5 M by sorption on strontium-specific sorbent. In special cases the following crown-ethers applied on a solid carrier are used as strontium-specific sorbents: 18-crown-6, dicyclohexano-18-crown-6, dicyclo-hexano-18-crown-6 with hydrophobic substitutes. It is possible to use the following crown-ethers applied on a solid carrier as strontium-specific sorbents: dicyclohexano-18- crown-6 containing alkyl substitutes, in part, crown-ether 4,4'(5')-di-(tert.-butylcyclohexano)-18-crown-6. Polymer of polyacrylate structure or copolymer of styrene with divinylbenzene is used as a solid carrier. Invention can be used for therapy of oncological diseases and for production of β-sources using in instrument making and biological investigations. EFFECT: increased yield of product, decreased consumption of reagents. 8 cl, 1 dwg
Patent RU-2187756-C1 (RU)
Title: Газовая многофакельная горелка
Inventor: EGOROV V A
IPC: F23D14/20
Filed: 2001-09-28
Granted: 2002-08-20
Abstract: Изобретение относится к энергетическому машиностроению, в частности к горелочным устройствам, работающим на природном газе с принудительной подачей воздуха, предназначенным преимущественно для использования в топках водогрейных котлов. Техническим результатом изобретения является уменьшение потерь напора в воздушном тракте, снижение уровня шума, более рациональная организация воздушного и газовых потоков, сокращение габаритов, упрощение конструкции и монтажа горелки. Газовая многофакельная горелка с принудительной подачей воздуха содержит камеру для подвода воздуха, камеру для подачи газа, в торцовых стенках которой выполнены соосно расположенные отверстия, смесители, выполненные в виде цилиндрических трубок с отверстиями в боковых стенках, и жаровую трубу, полость внутри которой сообщена с камерой для подвода воздуха. Согласно изобретению камера для подачи газа расположена между камерой для подвода воздуха и жаровой трубой, при этом полость внутри жаровой трубы сообщена с камерой для подвода воздуха посредством цилиндрических трубок смесителей, герметично установленных в отверстиях торцовых стенок камеры для подачи газа, и отверстия в боковых стенках цилиндрических трубок расположены внутри камеры для подачи газа. 2 ил.
Patent RU-2185286-C1 (RU)
Inventor: OSTRIKOV A N
IPC: B29C48/325
Filed: 2001-10-26
Granted: 2002-07-20
Abstract: FIELD: processing of thermoplastic materials, applicable in the branches of industry using extrusion. SUBSTANCE: moulding device has an extruder working chamber and an extrusion head consisting of a die with channels, core and a disk with holes. The disk is installed for turning. A cone-shaped deflector engageable with the core is installed in the predie zone of the extruder working chamber on guides. The deflector interior has a saddle shape with a cone and two holes. The core consists of a disk and a cylindrical shaft with bulges. The disk has two oval holes and stops on the side surface. A configurated hole is made in the center of the die, which receives the core cylindrical shaft. The shaft bulges form oval moulding channels in the die hole. Installed in the diametrical annular slot of the die are springs with one side engageable with the core disk stops, and with the other - with thrust washers. The washers are installed in symmetrically located slots of the die and working chamber so that the core could rotate in the die with formation of a different flow area of the oval moulding channels. EFFECT: stabilized pressure in the predie zone of the extruder at variation of the process parameters in the course extrusion of various feedstock. 8 dwg
Patent RU-2192393-C1 (RU)
Title: Состав для очистки воды
Inventor: PAVLOV M V
IPC: C02F103/42
Filed: 2001-11-20
Granted: 2002-11-10
Abstract: Изобретение относится к области обработки воды, к составам для очистки и обеззараживания воды, в том числе и в плавательных бассейнах. Предложен состав для обеззараживания воды, включающий полигексаметиленгуанидина фосфат, метиленовый синий и воду, причем он дополнительно содержит алкилдиметилбензиламмоний хлорид, изопропиловый спирт при следующем соотношении компонентов, мас. %: алкилдиметилбензиламмоний хлорид 6-10; метиленовый синий 0,05-0,5; изопропиловый спирт 0,5-1,5; полигексаметиленгуанидина фосфат 0,5-2,0; вода - остальное. Состав обеспечивает уничтожение болезнетворных бактерий, водорослей, при его использовании не происходит образования пены, а также состав ускоряет процесс очистки воды.
Patent RU-2201900-C1 (RU)
Title: Method of sewage treatment from heavy metal ions
Inventor: AKHMEDOV ARTYK
IPC: C02F1/28
Filed: 2001-12-04
Granted: 2003-04-10
Abstract: FIELD: sewage treatment. SUBSTANCE: invention relates to sewage treatment from heavy metal ions, mainly zinc ions, in metallurgy, electroplating, electric engineering, polygraphy and paper and pulp manufacture. Method involves treatment of sewage with sodium boron hydride as a reducing agent taken in the amount 10-50 mg/l of sewage. Then cellulose-containing milled hydrophilic sorbent that is product of waste of newspaper and typographic paper is added to the treatment zone in air medium of hammer crusher. Sorbent shows the following fraction composition, wt.%: small fraction of size 0.5-0.9 mm, 15-25; large fraction of size 1.0-1.5 mm, 75-85 in the amount 1-5 g/1 l of sewage. Method provides possibility of directed isolation of not only iron but other metals, mainly zinc, from sewage. EFFECT: improved method and enhanced effectiveness of treatment. 1 tbl
Patent RU-2209652-C1 (RU)
Inventor: GOLUB V V
IPC: B01D27/08
Filed: 2002-03-04
Granted: 2003-08-10
Abstract: FIELD: filtering processes; cartridge filters; water supply systems; food-processing and pharmaceutical industries. SUBSTANCE: proposed filter has housing with flow changeover unit rigidly connected with bush provided with longitudinal passage for communication with cavity of flow change-over unit. Longitudinal passage is stepped: larger diameter forms inlet hole and lesser diameter forms outlet hole. Mounted in inlet hole is bush with cavity having contraction coaxially relative to outlet hole widening in form of diffuser. Smaller diameter of cavity has longitudinal extension directed towards outlet hole, thus forming ejector together with it. Flow change-over unit is provided with filter element which is cleaned by reverse flow of liquid and air due to ejection effect every time during opening of outlet hole of housing. EFFECT: increased service life of filter; ease in use; simplified construction. 3 dwg
Patent RU-2219610-C1 (RU)
Title: Single-action thermal switch (alternatives) and electric heating element incorporating single- action thermal switch (alternatives)
Inventor: KOTOV V I
IPC: H05B3/46
Filed: 2002-04-19
Granted: 2003-12-20
Abstract: FIELD: electrical engineering; tubular electric heating elements protected against overheating in abnormal operation ( poor heat dissipation conditions). SUBSTANCE: thermal switch is proposed of three alternatives with respect to its mechanical design. Thermal switch of first alternative has temperature sensor in the form of open easy- melting metal or alloy tube filled with promoting agent whose fusing temperature and electric conductivity are lower than those of temperature sensor; two contacts made of metal tube and partially fitted onto opposing ends of temperature sensor and soldered to its outer surface. Contacts are spaced minimum 0.6 mm apart. Thermal switch of second alternative has its temperature sensor non-filled with promoting agent. Thermal switch has definite optimal dimensions. Thermal switch of third alternative is characterized in that its outer and/or inner surface, or all its surfaces are coated with thin layer of promoting agent. Electric heating element incorporating proposed single-action thermal switch is proposed of two alternatives. Heating element of first alternative has two contact leads and high-resistance spiral wire one of whose ends is rigidly fixed to one of contact leads and other end, to thermal switch. The latter has temperature sensor in the form of easy-melting conducting material tube and two contacts. Spiral wire end fixed to thermal switch is inserted in one of its contacts and clamped therein. Hole at end of spiral wire part inserted in thermal switch contact is closed with plug. Distance from spiral wire and plug to temperature sensor is minimum 0.1 mm. Second contact lead is partially inserted in second contact of thermal switch and clamped therein. Electric heating element of second alternative incorporating proposed thermal switch is provided with second spiral wire one of whose ends is fixed to contact lead and other one is inserted in contact of thermal switch and clamped therein. EFFECT: enhanced quality, simplified design. 14 cl, 17 dwg
Patent RU-2223645-C1 (RU)
Title: Insecticides sticker for pesticides
Inventor: ISHMURATOV A S
IPC: A01C1/06
Filed: 2002-05-27
Granted: 2004-02-20
Abstract: FIELD: agriculture, organic chemistry. SUBSTANCE: invention relates to chemical production used in agriculture. Sticker for pesticides comprises oligomeric polyalkoxysiloxanes, non-ionogenic surface-active substance and water-soluble organic solvent. As oligomeric polyalkoxysiloxanes mixture of oligoalkoxysiloxanes of the general formula: R[-O-Si(OR) 2 -O] n R wherein R means C 2 -C 3 -alkyl; n = 1-10 is used. As non-ionogenic surface-active substance mixture of polyethylene glycol esters of saturated alcohols of the general formula: HO(-CH 2 -CH 2 -O-) m R 1  wherein m = 2-10; R 1  is C 6 -C 12 -alkyl is used in the volume ratio polyalkoxysiloxanes to surface-active substance = 1 : (0.2-13). Sticker comprises a water-soluble solvent taken in the volume ratio to polyalkoxysiloxanes = 1 : (1-10) mainly. EFFECT: enhanced biological effectiveness of pesticides. 2 cl, 7 tbl
Patent RU-2206330-C1 (RU)
Inventor: KULEMIN L M
IPC: A61P37/00
Filed: 2002-05-30
Granted: 2003-06-20
Abstract: FIELD: medicine, microbiology. SUBSTANCE: agent comprises sterile bran, bacterial cells of strain Saccharomyces cerevisiae (vini) VKMP Y-511 grown on bran, biologically active substances and trace elements. Agent comprises bacterial cells of strain Saccharomyces cerevisiae (vini) VKMP Y-511 taken in the amount 2.55 x 10 10  - 2.65 x 10 10  microbial bodies/1 g of bran. Agent comprises food wheat sterile, red-yellow color bran without foreign odor as bran with concentration of trace elements 4.8-5.5%. Agent comprises, wt.-%: calcium, 0.10-0.15; phosphorus, 1.00- 1.40; sodium, 0.08-0.10; zinc, 106-109 x 10 -6  and iron, 114-118 x 10 -6 . Method for preparing agent involves culturing Saccharomyces cerevisiae (vini) VKMP Y-511 with bran by their preliminary wetting with water and the following heat treatment of medium and sterilization of the end product. Bran are wetted with water without any additional taste and odor before culturing, cloudness value is less 0.1, pH is 8.7, without chlorine and value of permanganate oxidizability mgO/dm 3  1.6 mg/dm 3 , not above, hardness 1.5 mg/dm 3 , total mineralization 384 mg/dm 3 , not above. Heat treatment in the process of culturing is carried out by uniform heating all culturing medium. EFFECT: valuable medicinal properties of agent, improved preparing method. 2 cl, 4 tbl
Patent RU-2224580-C1 (RU)
Title: Filter member for gases cleaning and drying
Inventor: CHERNORUBASHKIN ALEKSANDR IVAN
IPC: B01D53/04
Filed: 2002-08-01
Granted: 2004-02-27
Abstract: FIELD: different gases cleaning and drying. SUBSTANCE: the invention presents a filter member, that may be used for different gases cleaning with simultaneous drying. The offered filter member includes: two or more concentrically inserted one into another cylinders, the walls of which are made of the thermoplastic polymer fibers thermally fixed in places of the fibers intersections. At that a diameter of fibers, that form the first cylinders (along the run of the cleaned gas) is bigger and the density of their laying is lower, than in the following cylinders. Spaces between the cylinders are filled in with the granular hygroscopic material, which particles sizes are within the limits from 0.05 up to 1 mm, and the mean diameter of pores of the first (along the run of the cleaned gas) cylinder is no more than 0.05 mm to prevent the granular material pouring out. Total thickness of all layers with the granular material of the filter member is no less than 60 mm. In the capacity of a thermoplastic polymer it is possible to use polyethylene or polypropylene, and in the capacity of the granular material - silica gel or calcium chloride. The service life of such filter members may be increased by replacement of the first cylinders (along the run of the cleaned gas) and by regeneration of the granular material (using calcination). EFFECT: high efficiency and a long term of operation. 3 cl, 1 tbl
Patent RU-2232669-C1 (RU)
Inventor: SOKOLOV G N
IPC: B23K25/00
Filed: 2002-11-11
Granted: 2004-07-20
Abstract: FIELD: manufacture of parts of machines and tools with use of surfacing operation. 
     SUBSTANCE: method comprises step of creating slag bath in volume restricted by surfaced face and sectional crystallizing pan; keeping temperature of surface of crystallizing pan higher than temperature of sharp raising of viscosity of used slag; realizing electroslag surfacing at introducing to rotating slag bath non-consumable hollow electrode connected with autonomous power source and having cone working portion; submerging electrode into slag bath by depth equal to height of electrode cone; providing high temperature region with size 2 - 2.5 diameters of electrode in slag bath; feeding surfacing material into high-temperature region through cavity of non-consumable electrode; selecting ratio of welding electric current and electric current applied to non-consumable electrode in range 1.3 - 2.0. High heating temperature and intensified agitation provide uniform melting of surfacing materials containing refractory components. 
     EFFECT: enhanced quality of surfaced ends. 
     3 cl, 4 dwg, 1 tbl, 4 ex