baber/WOPTO huggingface dataset:
Patent AU-2019202036-A1 (AU)
Title: Identifying patient response to S1P receptor modulator administration
Inventor: BORELL HUBERT
IPC: G01N33/50
Filed: 2019-03-25
Abstract: 1:\dar\nterwovn\NRPortbl\DCC\DAR\13911369_l.docx-ll/04/2017 The invention provides a method of assessing the appropriate therapeutic dose of 1-{4-[1-(4 cyclohexyl-3-trifluoromethyl-benzyloxyimino)-ethyl]-2-ethyl-benzyl}-azetidine-3-carboxylic acid to administer to a patient in need thereof, comprising the steps of: (i) testing whether or not the patient has the poor metabolizer genotype; and (ii) if the patient does not have the poor metaboliser genotype, administering 1 {4-[1-(4-cyclohexyl-3-trifluoromethyl-benzyloxyimino)-ethyl]-2-ethyl-benzyl} azetidine-3-carboxylic acid, or a pharmaceutically acceptable salt thereof, to the patient at the standard therapeutic dose; and (iii) if the patient does have the poor metaboliser genotype, either (a) administering 1-{4-[1-(4-cyclohexyl-3-trifluoromethyl-benzyloxyimino) ethyl]-2-ethyl-benzyl}-azetidine-3-carboxylic acid, or a pharmaceutically acceptable salt thereof, to the patient at a therapeutic dose below that of the standard therapeutic dose; or (b) not administering 1-{4-[1-(4-cyclohexyl-3-trifluoromethyl-benzyloxyimino) ethyl]-2-ethyl-benzyl}-azetidine-3-carboxylic acid, or a pharmaceutically acceptable salt thereof, to the patient.
Patent AU-2019205203-A1 (AU)
Title: Port interface for drug delivery device
Inventor: RABOLLI CHRISTINA
IPC: A61M5/142
Filed: 2019-01-02
Abstract: A drug delivery device includes a housing, a cartridge received within the housing, with the cartridge configured to receive a medicament, a drive assembly received within the housing and configured to engage the cartridge and dispense medicament from the cartridge, and a needle actuator assembly received within the housing, with the needle actuator assembly including a patient needle configured to pierce a patient's skin. A bottom surface of the housing defines a port interface configured to receive an implanted injection port.
Patent AU-2019208322-A1 (AU)
Title: Topical capecitabine for the treatment of hyperproliferative skin conditions
Inventor: AVRAMOFF AVI
IPC: A61K31/167
Filed: 2019-01-18
Abstract: The present invention relates to a novel and unexpected method of using topical Capecitabine composition to obtain therapeutically effective amounts of fluorouracil (FU) within the skin of a subject afflicted with hyperproliferative or inflammatory skin condition. The method comprising topically administering a pharmaceutical composition comprising Capecitabine or a hydrate or solvate thereof to the affected area of the skin of the subject, to form therapeutically effective amounts of FU within the skin.
Patent AU-2019216707-A1 (AU)
Title: Modified release formulations of viloxazine
Inventor: VIEIRA MICHAEL L
IPC: A61K9/20
Filed: 2019-08-16
Abstract: MODIFIED RELEASE FORMULATIONS OF VILOXAZINE Modified release formulations of viloxazine and methods of administering the same are disclosed. High- drug load formulations of viloxazine are further disclosed.
Patent AU-2019236695-A1 (AU)
Title: Multi-fuel engine system
Inventor: FLYNN PAUL LLOYD
IPC: F02D35/02
Filed: 2019-09-26
Abstract: Various methods and systems are provided for an engine capable of receiving liquid and gaseous fuel. In one example, cylinder misfire may be identified based on a misfire monitor. The misfire monitor may detect misfire based on signals from a crankshaft sensor.
Patent AU-2019250612-A1 (AU)
Title: Kit, composition and combination therapy for fragile x syndrome
Inventor: BROWN DAVID
IPC: A61P25/00
Filed: 2019-04-12
Abstract: The present invention relates to a kit comprising: (i) at least one dose of sulindac, or a pharmaceutically acceptable salt thereof; and (ii) at least one dose of Compound A, or a pharmaceutically acceptable salt thereof, for the treatment of fragile x syndrome.
Patent AU-2019251260-A1 (AU)
Title: A display panel
Inventor: DAYARAM DINESH MUKESH
IPC: G09F19/00
Filed: 2019-04-10
Abstract: An information panel or display panel (100) suitable for mounting onto the top of a vehicle (301) is disclosed. Information such as advertisement can be changed automatically. Change of advertisement content is responsive to the speed of the vehicle (301).
Patent AU-2019254467-A1 (AU)
Title: Device and method for controlling the stability of a dental implant
Inventor: HAIAT GUILLAUME
IPC: A61B8/08
Filed: 2019-04-16
Abstract: The invention relates to a device for controlling the stability of a dental implant (1) in a bone (2), the implant having a free end (1a) and an end (1b) inserted in the bone (2). The device comprises an ultrasonic transducer (12) for emitting and collecting an ultrasonic wave reflected on a contact interface (4) between the implant (1) and the bone (2), and supplying a measuring signal representing the reflected ultrasonic wave. The device also comprises a processing unit for calculating, from the measuring signal, an indicator (IN) having a value that allows the evaluation of the integration of the implant (1) into the bone (2). The indicator (IN) corresponds to the average energy of the measuring signal over a time interval (t1-t2) starting at a first instant (t1) and ending at a second instant (t2). The first instant (1) is between 20 and 80 ps after the beginning of the emission of the ultrasonic wave.
Patent AU-2019272377-A1 (AU)
Title: Heteroaromatic compounds, pharmaceutical compositions and uses thereof
Inventor: ZHANG JIANCUN
IPC: A61P35/00
Filed: 2019-05-22
Abstract: The present invention provides a novel aromatic heterocyclic compound serving as an ATX (Autotaxin) inhibitor, a pharmaceutical composition containing the compound, and a use of the compound and the composition in treating a disease having a pathological characteristic of increased ATX expression in mammals. The compound has a structure as represented by formula (I), or a pharmaceutically acceptable salt thereof, a hydrate, a solvate, a stereoisomer, a tautomer, a nitrogen oxide, a metabolite, a prodrug, or a mixture. R
Patent AU-2019284031-A1 (AU)
Title: Antibodies to aripiprazole and use thereof
Inventor: HRYHORENKO ERIC
IPC: C07K14/00
Filed: 2019-12-23
Abstract: Disclosed is an antibody which binds to aripiprazole, which can be used to detect aripiprazole in a sample such as in a competitive immunoassay method. The antibody can be used in a lateral flow assay device for point-of-care detection of aripiprazole, including multiplex detection of aripiprazole, olanzapine, quetiapine, and risperidone in a single lateral flow assay device.
Patent AU-2019291965-A1 (AU)
Title: Computer vision systems and methods for modeling three dimensional structures using two-dimensional segments detected in digital aerial images
Inventor: ESTEBAN JOSE LUIS
IPC: G06K9/46
Filed: 2019-07-01
Abstract: A system for modeling a three-dimensional structure utilizing two-dimensional segments comprising a memory and a processor in communication with the memory. The processor extracts a plurality of two-dimensional segments corresponding to the three- dimensional structure from a plurality of images indicative of different views of the three- dimensional structure. The processor determines a plurality of three-dimensional candidate segments based on the extracted plurality of two-dimensional segments and adds the plurality of three-dimensional candidate segments to a three-dimensional segment cloud. The processor transforms the three-dimensional segment cloud into a wireframe indicative of the three-dimensional structure by performing a wireframe extraction process on the three-dimensional segment cloud.
Patent AU-2019300360-A1 (AU)
Title: Method for determining a dose of coagulant for treating raw water
Inventor: HASSANZADEH SEPIDEH
IPC: C02F1/52
Filed: 2019-07-12
Abstract: The invention concerns a method for determining an optimal dose of coagulant for raw water comprising: − a step of determining a value, for the raw water, of a first organic parameter; − a step of determining a value, for the raw water, of a second mineral parameter; − a step of determining a class of water for the raw water, characterised by the value of the first organic parameter and the value of the second mineral parameter; − a step of determining a value, for the raw water, of a third organic parameter; − a step of defining a target value, for the clarified water, of the third organic parameter; − a step of selecting a function between the third organic parameter and an added dose of coagulant, said function being selected for the class of water and for the value, for the raw water, of the third organic parameter; − a step of using the function to determine a first dose of coagulant in order to reach the target value.
Patent AU-2019302312-A1 (AU)
Title: System for realizing automated transport of goods and related apparatus
Inventor: WU NAN
IPC: G05B19/418
Filed: 2019-03-05
Abstract: A system for realizing the automated transport of goods and a related apparatus can realize the fully automated transport of goods in a specific area. The system comprises a management system (1), a loading and unloading control apparatus (3), and an automated driving control apparatus (2) disposed on an automated vehicle, wherein: the management system (1) is used to manage goods information and a transport state of the automated vehicle; the automated driving control apparatus (2) is used to generate a transport task according to the goods information and the transport state of each automated vehicle, and sending each of the transport tasks to the matching automated vehicle; the automated driving control apparatus (2) is used to control the automated vehicle to perform the transport according to the transport task upon receiving the transport task; the loading and unloading control apparatus (3) is used to control a loading and unloading apparatus to perform automated loading and unloading of goods to and from the automated vehicle.
Patent AU-2019304199-A1 (AU)
Title: Amino acid containing oral care composition for treating caries by reducing lactic acid release in oral biofilms
Inventor: SCHMID BRENDA
IPC: A61Q11/00
Filed: 2019-07-11
Abstract: The invention relates to a composition for use in a method of treating caries by reducing the lactic acid release of lactic acid producing bacteria in an oral biofilm of a human being or animal, the composition comprising one or more amino acid(s) dissolved or dispersed in water, the amino acid(s) being selected from glycine, leucine, isoleucine, lysine, methionine, phenylalanine, serine, threonine, valine, tryptophan and mixtures thereof. The invention also relates to a kit of parts for use in a method of treating caries by reducing the caries activity or reducing the lactic acid release of lactic acid producing bacteria in an oral biofilm, the kit of parts comprising Part A comprising certain amino acid(s), Part B comprising water, and optionally Part C comprising an application device.
Patent AU-2019315447-A1 (AU)
Title: Systems, apparatus and methods for collecting and separating floating debris and water from a body of water
Inventor: COVINGTON RUSSELL S
IPC: E02B15/10
Filed: 2019-07-31
Abstract: Systems, apparatus and methods useful for collecting and separating floating debris and water from a body of water on a vessel, the vessel including at least one inflow regulator (IFR) chamber at least partially separated from a main collection compartment and at least one fluid discharge pump.
Patent AU-2019322885-A1 (AU)
Title: Automatic fire sprinklers, systems and methods for suppression fire protection of high hazard commodities including commodities stored in rack arrangements beneath ceilings of up to fifty-five feet in height
Inventor: WORKMAN MARTIN H
IPC: A62C35/60
Filed: 2019-08-15
Abstract: System and methods to provide ceiling-only suppression fire protection of up to fifty feet (50 ft.) of rack storage of cartoned unexpanded plastic commodities and less hazardous commodities, such as for example, Class 1, Class 2, Class 3, Class 4 and/or combinations thereof beneath a ceiling having a maximum ceiling height up to fifty-five feet (55 ft.). The systems and methods provide for hydraulic and system parameters that include a hydraulic design area based upon five to no more than twelve hydraulically most remote sprinklers spaced at a preferred sprinkler-to-sprinkler spacing of eight to ten feet (8-10 ft.) coupled to two to four branch lines tied to a common cross main supply pipe of firefighting fluid.
Patent AU-2019370538-A1 (AU)
Title: CSI feedback and receiving methods, apparatus, device, and storage medium
Inventor: WU HAO
IPC: H04B7/0417
Filed: 2019-11-01
Abstract: Provided in the embodiments of the present invention are CSI feedback and receiving methods, an apparatus, a device, and a storage medium, the CSI feedback method comprising: a terminal determines PMI, the PMI comprising at least one of first base vector information, second base vector information, second coefficient amplitude information and phase information; for one transmission layer, a precoding vector corresponds to a frequency domain resource in a preset frequency domain unit, the precoding vector being a linear merging of first base vectors, and the weighting coefficient used for the linear merging of the first base factors being a first coefficient; on the multiple frequency domain units included in the CSI feedback bandwidth, the vector composed of the first coefficients corresponding to the same first base vector is a linear merging of the second base vectors, and the second coefficient is the weighting coefficient used for linear merging of the second base vectors; the terminal feeds back CSI comprising the PMI to a base station.
Patent AU-2019398753-A1 (AU)
Title: Cell composition comprising liver progenitor cells expressing HLA-E
Inventor: TCHELINGERIAN JEAN-LEON
IPC: C12N5/071
Filed: 2019-12-12
Abstract: The current invention concerns isolated liver progenitor cells, cell lines thereof, cell populations comprising such and compositions comprising such wherein the liver progenitor cells are HLA-E positive. In addition, the invention concerns methods of preparing these liver progenitor cells.
Patent AU-2019407909-A1 (AU)
Title: Substituted oxopyridine derivatives
Inventor: Röhrig Susanne
IPC: C07D491/044
Filed: 2019-12-18
Abstract: The invention relates to substituted oxopyridine derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular vascular disorders, preferably thrombotic or thromboembolic disorders and/or thrombotic or thromboembolic complications.
Patent AU-2019408048-A1 (AU)
Title: Lipopeptide building blocks and synthetic virus-like particles
Inventor: GHASPARIAN ARIN
IPC: C12N7/00
Filed: 2019-12-19
Abstract: The present invention relates to a lipopeptide building block consisting of (i) a peptide moiety comprising a coiled coil peptide chain segment, wherein said coiled coil peptide chain segment comprises 3 to 8 repeat units, and wherein said repeat unit consists of the sequence IEKKIE-XO (SEQ ID NO:58), wherein X0 represents an amino acid, and wherein preferably said repeat unit consists of the sequence selected from IEKKIEG (SEQ ID NO:59), IEKKIEA (SEQ ID NO:12) or IEKKIES (SEQ ID NO:13), and wherein further preferably said repeat unit consists of the sequence IEKKIES (SEQ ID NO:13); (ii) a lipid moiety comprising, preferably consisting of, the formula LM-I wherein R
Patent AU-2019418359-A1 (AU)
Title: Refrigerator and control method and control device thereof
Inventor: FANG RUIMING
IPC: F25C1/00
Filed: 2019-01-03
Abstract: Disclosed by the present application are a refrigerator and control method and control device thereof, said method comprising: detecting and confirming that a refrigerator is in a first control cycle after defrosting; detecting and confirming that an ice-making evaporator requests cooling, and controlling a control valve to be in communication with an ice-making circuit. The method controls the refrigerant to preferentially enter the ice-making circuit after the refrigerator defrosts, effectively reducing the time that an ice-making compartment is in a high-temperature state due to defrosting, and decreasing the risk of ice cubes melting and then re-freezing to cause ice cubes to stick, and is conducive to the long-term high-quality storage of ice cubes.
Patent AU-2020200214-A1 (AU)
Title: Organ protection in PSMA-targeted radionuclide therapy of prostate cancer
Inventor: BABICH JOHN W
IPC: A61K51/04
Filed: 2020-01-10
Abstract: A method of reducing radiation exposure of a non-cancerous tissue of a patient diagnosed with a cancer includes administering to the patient an agent capable of competing for binding sites on a surface of the non-cancerous tissue, provided that the administration is carried out after a waiting period that follows administration of a compound including a radionuclide to the patient, the compound having affinity for both a cancerous tissue and the non-cancerous tissue, and, further provided that the binding sites have an affinity for both the agent and the compound. [1251]MIP1095 PMPA CLEARANCEb 16h ~h 20hb22h 46-8h 16h 1h20h 22h 46-48h CONTROL: ~ 0.2mg/kg: I 4 ? I1mg/kg I10mg/kg: h 50mg/kg:
Patent AU-2020203534-A1 (AU)
Title: Pivot Block
Inventor: PELEKANOS STYLIANOS
IPC: E05D15/26
Filed: 2020-05-29
Abstract: :1\Interwovn\NRPortbl\DCC\KMIl\20257138_I.docx-28/05/2020 A pivot block including a first part for holding a bolt of an associated folding panel, and a 5 second part that is able to be fixed to a track so as to position the first part and the bolt at a location whereby the folding panel is able to pivot about pivot bolt, wherein the first part is moveable relative to the second part lengthwise of the track, for adjustment of the position of the pivot bolt. 04) LC)) C')4
Patent AU-2020212228-A1 (AU)
Title: Novel bispecific antibody molecule and bispecific antibody simultaneously combining PD-L1 and LAG-3
Inventor: NI HAIQING
IPC: A61P31/00
Filed: 2020-01-23
Abstract: A novel artificially designed antibody molecule. The novel artificially designed antibody molecule comprises a polypeptide chain of formula (I): VH-CH1-Fc-X-VHH; and a polypeptide chain of formula (II): VL-CL; wherein VH represents a heavy chain variable region; CH represents a heavy chain constant region; Fc contains CH2, CH3, and optional CH4; CH1, CH2, CH3, and CH4 respectively represent structural domains 1, 2, 3, and 4 of the heavy chain constant region; X may not exist, or represents a joint such as a flexible joint when existing; VHH represents a single structural domain antigen binding site, such as a single structural domain antibody; VL represents a light chain variable region; CL represents a light chain constant region; and optionally, a hinge region exists between CH1 and Fc.
Patent AU-2020220231-A1 (AU)
Title: Remotely controlling a hydraulic system
Inventor: LEWIS SHANE RUSSELL
IPC: G05B11/60
Filed: 2020-02-07
Abstract: In one aspect, a system (110) for performing an action is disclosed. In one arrangement and embodiment, the system (110) comprises: a tool (118) operable to perform at least the action; a controller (122); storage (124) storing electronic program instructions for controlling the controller (122); and an input/output means (126). In one form, the controller (122) is operable, under control of the electronic program instructions, to: receive input via the input means; process the input, and on the basis of the processing, control the tool to perform the action. In one embodiment, the action comprises a hydraulic tuning action in respect of a system, such as a hydraulic pump (114), comprising a hydraulic circuit.
Patent AU-2020225112-A1 (AU)
Title: A product dispensing system, holder and manufacturing method
Inventor: BULSINK DIRK JAN
IPC: A23P30/40
Filed: 2020-02-18
Abstract: A product dispensing system, including a holder (H) which contains a product (P) to be dispensed, the holder (H) having a product processing unit (PPU) for processing and discharging product coming from the holder (H), wherein the product processing unit (PPU) is provided with a microfiltration device (15) which is provided with a product entrance for supply of product (P), wherein the microfiltration device (15) is connectable to a gas supply for supplying gas to the product during product discharge, wherein the microfiltration device is provided with a housing (15c) defining an interior processing space, wherein the processing space is separated by a tubular microfiltration element (15a), having gas transmissive pores, into a gas supply space (15d) from a product feed-through channel (15b), wherein the gas supply space (15d) is associated with a gas inlet (8) of the housing and the product feed-through channel (15b) is associated with a product entrance (15i) of the housing, wherein the housing (15c) includes an exit (15u) for discharge of product provided with gas.
Patent AU-2020228134-A1 (AU)
Title: Fragile X mental retardation protein interfering oligonucleotides and methods of using same
Inventor: VITI FRANCESCA
IPC: C12N15/113
Filed: 2020-02-26
Abstract: Disclosed herein are antisense oligonucleotide sequences against fragile X mental retardation protein (FMRP) and methods of using the same for treating bowel diseases such as colorectal cancer and inflammatory bowel disease (e.g., Crohn's disease and ulcerative colitis), associated with elevated activity or expression of FMRP. Also disclosed are pharmaceutical compositions containing an FMRP antisense oligonucleotide useful for treating a bowel disease and manufacture of medicaments containing a disclosed FMRP antisense oligonucleotide to be used in treating a bowel disease.
Patent AU-2020237079-A1 (AU)
Title: Method and apparatus for video encoding or decoding
Inventor: ZHAO XIN
IPC: H04N19/10
Filed: 2020-03-11
Abstract: A method and apparatus for encoding or decoding a video sequence includes encoding or decoding the video sequence using a 4:4:4 chroma format, or encoding or decoding the video sequence using a 4:2:2 chroma format, wherein when encoding or decoding the video sequence using the 4:4:4 chroma format, copying an affine motion vector of one 4x4 chroma block using an operation other than an averaging operation, and when encoding or decoding the video sequence using the 4:2:2 chroma format, associating each 4x4 chroma block with two 4x4 co-located chroma blocks such that an affine motion vector of one 4x4 chroma block is an average of the motion vectors of the two co-located chroma blocks.
Patent AU-2020241059-A1 (AU)
Title: System for rail grinding
Inventor: BARTHEL BRIAN P
IPC: E01B31/17
Filed: 2020-03-03
Abstract: Rail grinders and related methods of rail grinding in which custom grinding patterns are continually updated based upon an operational status of the rail grinder. The rail grinder includes a plurality of individual grinding modules that are individually arranged to generate the custom grinding patterns for individual rail segments. The custom grinding patterns allow the rail grinder to grind a desired rail profile for each rail segment in a minimum number of grinder passes and at a maximum operating speed for the rail grinder. Utilizing a variety of inputs including current rail conditions, desired rail profile, rail segment type, available grinding modules and grinding module style, a processing system either on-board or remotely located from the rail grinder can iteratively develop a custom grinding pattern that is temporally unique to each rail segment.
Patent AU-2020243056-A1 (AU)
Title: Transglutaminase conjugation method with a glycine based linker
Inventor: SCHIBLI ROGER
IPC: A61P35/00
Filed: 2020-03-19
Abstract: The present invention relates to a method for generating an antibody-payload conjugate by means of a microbial transglutaminase (MTG). The method comprises a step of conjugating a linker comprising or having the peptide structure (shown in N->C direction) Gly-(Aax)