baber/WOPTO huggingface dataset:
Patent TW-202325669-A (TW)
Title: Method for making agricultural chemicals using biological sludge capable of fully utilizing resource ingredients beneficial for agriculture contained in biological sludge
Inventor: LIN ZHI-YAN
IPC: A01N63/23
Filed: 2021-12-28
Abstract: A method for making agricultural chemicals using biological sludge includes a pre-processing step, a separation step, a solid state processing step, and a liquid state processing step. The pre-processing step is to place biological sludge in a processing space, and introduce ozone and provide high-pressure hydraulic power, in order to destroy the cell walls of the cells contained in the biological sludge by ozone reaction and hydraulic oscillation and dissolve intracellular substances. The separation step is to separate a cell lysis slag and a cell lysate. The solid state processing step includes a hydraulic sub-step for further thinning the cell lysis slag, a dehydration sub-step for removing the moisture contained in the cell lysis slag, and a drying sub-step for drying the cell lysis slag to produce a high protein substance. The liquid state processing step includes a concentration sub-step for filtering the cell lysate to increase the concentration of the cell lysate, and thus to produce a biostimulant.
Patent TW-202237156-A (TW)
Inventor: NAYAK SUBHENDU
IPC: A61K35/744
Filed: 2015-12-31
Abstract: This document provides bacterial compositions. For example, bacterial compositions having a combination of different bacterial strains formulated in a manner to maintain the stability of the bacteria are provided.
Patent TW-202337072-A (TW)
Inventor: HSIAO CHI-CHENG
IPC: H01M50/249
Filed: 2022-03-02
Abstract: 一種電源供應裝置包含一第一電池模組及一第二電池模組。第一電池模組包含一第一殼體及一第一電池組。第一殼體具有一第一容置空間及一第一開口。第一開口連通第一容置空間。第一電池組固定於第一容置空間內。第二電池模組包含一第二殼體及一第二電池組。第二殼體具有一第二容置空間及一第二開口。第二開口連通第二容置空間。第二電池組固定於第二容置空間內。其中，第一殼體裝設於第二殼體，且第一殼體與第二殼體各為一體成型之結構以及第一殼體與第二殼體的形狀與尺寸相同。
Patent TW-202300414-A (TW)
Title: Packaging bag for filling crushed polysilicon material and polysilicon package
Inventor: ASANO TAKUYA
IPC: B65D77/04
Filed: 2022-03-03
Abstract: This packaging bag for filling crushed polysilicon material is a packaging bag for directly packaging crushed polysilicon material, the packaging bag being configured of a multilayer film in which a polyethylene resin layer without additives is arranged as the innermost layer and at least a gas barrier layer and a reinforcing material layer are laminated on the polyethylene-based resin layer.
Patent TW-202225804-A (TW)
Inventor: MIYAIRI HIDEKAZU
IPC: H01L29/786
Filed: 2009-11-19
Abstract: 當顯示裝置具有更高的清晰度時，像素的數目會增加，且因此，閘極線及信號線的數目會增加；當閘極線及信號線的數目增加時，很難以藉由接合法或其類似方法來安裝包含用以驅動閘極線及信號線之驅動器電路的IC晶片。像素部及用以驅動像素部的驅動器電路係設置於同一基板之上，且驅動器電路之至少一部分包含具有氧化物半導體的薄膜電晶體，該氧化物半導體係插置於閘極電極之間，通道保護層係設置於氧化物半導體與設置在該氧化物半導體之上的閘極電極之間。像素部及驅動器電路係設置於同一基板之上，而產生製造成本的降低。
Patent TW-202330010-A (TW)
Title: Saffron flower fermentate, topical skin composition including the same with effects of oil-controlling and redness relieving and use thereof
Inventor: FANG HSIANG-MING
IPC: A61K36/88
Filed: 2022-03-22
Abstract: The present invention is related to a saffron flower fermentate, a topical skin composition including the same with effects of oil-controlling, redness reliving and the use thereof, in which the saffron flower fermentate is made by performing a fermenting step on the saffron flower with yeast. The saffron flower fermentate contains high amounts of hydroxysafflor yellow A. Moreover, the saffron flower fermentate has antioxidant activities, and has the effects such as oil-controlling and/or redness-reducing on the skins.
Patent TW-202247500-A (TW)
Title: Thermoelectric conversion module
Inventor: NAKAI HIROSHI
IPC: H01L35/04
Filed: 2022-04-08
Abstract: This thermoelectric conversion module (1) comprises: a lower substrate (10) and an upper substrate (20) that are a pair of support substrates arranged facing each other; a plurality of thermoelectric conversion elements (30) arranged between the lower substrate (10) and the upper substrate (20); a temperature detection element (40) arranged on one support substrate of the lower substrate (10) and the upper substrate (20); and a sealing member (50) positioned between the peripheral edge part of the lower edge substrate (10) and the upper substrate (20), and formed to surround the plurality of thermoelectric conversion elements (30) in top view. In top view, the temperature detection element (40) is positioned between the plurality of thermoelectric conversion elements (30) and the edge of one support substrate, and the sealing member (50) covers the temperature detection element (40), and contacts at least one of the plurality of thermoelectric conversion elements (30).
Patent TW-202300334-A (TW)
Title: Laminate and manufacturing method thereof characterized in that a thermoplastic resin layer, a primer layer, and a metal layer are sequentially laminated on the insulating substrate
Inventor: FURUTANI Akinori
IPC: H01B1/02
Filed: 2022-04-19
Abstract: The present invention provides a laminate having a smooth interface between an insulating substrate having a thermoplastic resin on its outermost layer and a metal layer formed thereon, and excellent in adhesion between an insulator and the metal layer, and further provides a manufacturing thereof and a printed wiring board manufactured by using the laminate. A laminate excellent in adhesion can be found by using the following laminate, which is characterized in that a thermoplastic resin layer (B), a primer layer (C), and a metal layer (D) are sequentially laminated on an insulating substrate (A).
Patent TW-202303996-A (TW)
Inventor: CHEN WENLIANG
IPC: H01L29/92
Filed: 2022-05-18
Abstract: 本發明提供一種電容結構。所述電容結構包括基板、中段製程(MEOL)結構和金屬化結構。所述基板具有第一表面以及與第一表面相對的第二表面。MEOL結構位於基板的第一表面上。所述MEOL結構包括電容器，所述電容器包括底板和位於底部金屬板上的頂板。所述金屬化結構位於MEOL結構上。所述基板還包括從基板的第二表面延伸至底部金屬板的多個第一貫穿通路。本發明還提供了一種包括所述電容結構的半導體結構以及製造所述半導體結構的方法。
Patent TW-202306064-A (TW)
Inventor: NISHIWAKI KAZUHIRO
IPC: H01L23/467
Filed: 2022-06-21
Abstract: 揭示一種基材處理設備。一例示性基材處理設備包括一反應室；一基座板，其定位於反應室內，經建構及配置以支撐一基材，且設有一或多個孔洞；一基材升降機構，其包含：用以支撐基材的複數個升降銷；及用以移動升降銷的一升降銷支撐構件；在一垂直方向上通過一或多個孔洞；一基材轉移機器人，其設有一或多個機械手臂，用以將基材轉移至在升降銷上方之一位置；及一氣體供應單元，其經建構及配置以面向基座板；其中氣體供應單元經建構及配置以在垂直方向上移動，藉此將氣體供應單元定位在反應室中之一處理位置中。
Patent TW-202314837-A (TW)
Title: Polishing apparatus and polishing method
Inventor: ITO MASAYOSHI
IPC: H01L21/304
Filed: 2022-06-23
Abstract: The present invention provides a polishing apparatus and a polishing method capable of monitoring the distribution of the amount of liquid such as polishing liquid and chemical liquid on the polishing surface of a polishing pad and polishing an object to be polished such as a wafer under appropriate polishing conditions. A polishing device is provided with: a polishing table (5) that supports a polishing pad (2); a polishing head (7) that presses an object (W) to be polished against the polishing surface (2a) of the polishing pad (2); a liquid supply device (8) for supplying a liquid onto the polishing surface (2a); a liquid monitoring device (12) that acquires optical information included in light from a plurality of dots on the polishing surface (2a); an optical information analysis unit (13) that determines the distribution of the amount of liquid on the polishing surface (2a) on the basis of the optical information; and an operation control unit (47) that controls the operation of the polishing device.
Patent TW-202310374-A (TW)
Title: Semiconductor device
Inventor: HUANG YEN-CHIEH
IPC: H01L29/04
Filed: 2022-07-15
Abstract: A semiconductor device is described. The semiconductor device includes a substrate and a metal layer disposed on the substrate. A seed layer is formed on the metal layer. A ferroelectric gate layer is formed on the seed layer. A channel layer is formed over the ferroelectric gate layer. The seed layer is arranged to increase the orthorhombic phase fraction of the ferroelectric gate layer.
Patent TW-202304436-A (TW)
Title: Pharmaceutical combination and application thereof
Inventor: Li yong-guo
IPC: A61K31/444
Filed: 2022-07-27
Abstract: A pharmaceutical combination and an application thereof. The pharmaceutical combination comprises a PI3K inhibitor and an immune checkpoint inhibitor, wherein the PI3K inhibitor is selected from a compound represented by formula (I), linperlisib, samotolisib, copanlisib, SHC014748M, pilaralisib, buparlisib, taselisib, YZJ-0673, gedatolisib, omipalisib, bimiralisib, voxtalisib, AL58805, and HEC68498, and pharmaceutically acceptable salts thereof, and the immune checkpoint inhibitor is a PD-1/PD-L1 inhibitor. The compound represented by formula (Ia) has a high inhibitory effect on PI3K[delta] and PI3K[gamma] kinases, and the pharmaceutical combination uses a PI3K inhibitor and a PD-1 inhibitor in combination, thereby effectively improving the inhibitory effect on tumors, and solving the problem of drug resistance of PD-1/PD-L1 inhibitors.
Patent TW-202322362-A (TW)
Inventor: HARADA NOZOMU
IPC: H01L27/108
Filed: 2022-08-09
Abstract: Material layers including first and second poly-Si layer are formed on a P-layer substrate. Holes which are parallel to each other and each of which is continuous in a first direction are formed in the material layers. The first and second poly-Si layers are each divided by the holes in a second direction orthogonal to the first direction in plan view. Gate insulating layers and P-layer Si pillars are formed in the holes. The P-layer Si pillars are isolated from one another by the gate insulating layers. A dynamic flash 
memory is formed in which a first gate conductor layer is connected to a plate line, a second gate conductor layer is connected to a word line, the P-layer Si pillars serve as channels, and one of the N +  layers below and above the P-layer Si pillars is connected to a source line.
Patent TW-202314136-A (TW)
Title: Limited stroke linear guide device
Inventor: MIYAJIMA AYAKO
IPC: F16C29/04
Filed: 2022-08-15
Abstract: A limited stroke linear guide device comprising: a guide member (3) which has a guide groove (30) and is formed in a channel shape; a shaft member (4) which moves in the guide groove (30) along the longitudinal direction of the guide groove (30); multiple rolling elements which roll between the guide member (3) and the shaft member (4) while bearing a load; and a cage (5) which is disposed in the guide groove (30) of the guide member (3) so as to be present in a gap between the guide member (3) and the shaft member (4) and in which the multiple rolling elements are rotatably arranged. Stoppers (6) against which the cage (5) abuts are provided at both ends of the guide member (3) in the longitudinal direction. In the shaft member (4), a long restriction hole (42) is formed along the moving direction of the shaft member (4). Meanwhile, a locking protrusion (50) having a tip portion for insertion in the restriction hole (42) is erected on the cage (5).
Patent TW-202326308-A (TW)
Title: 腔室控制的自動調諧和處理性能評估方法
Inventor: CIMINO MAURO
IPC: G05B11/42
Filed: 2022-08-18
Abstract: 本文揭示的實施例包括一種用於自動調諧系統的方法。在一實施例中，該方法包含確定系統是否處於穩態。此後，該方法包括激發系統。在一實施例中，該方法包含儲存來自激發系統的製程反饋測量以提供一組儲存資料。在一實施例中，該組儲存資料為由激發系統產生的所有可用資料的子集。在一實施例中，該方法進一步包含確定該激發系統何時返回穩態，並且使用該組儲存資料調諧系統。
Patent TW-202324201-A (TW)
Title: Rfid arrangement, piece of jewelry, local sending arrangement, and methods
Inventor: KOH THONG HEE
IPC: G06K19/077
Filed: 2022-08-25
Abstract: The invention relates to an RFID arrangement comprising an RFID tag and a housing at least partially enclosing the RFID tag, wherein the RFID tag has a first contact and a second contact, and wherein the first contact is electrically connected to the housing. The invention relates further to a corresponding piece of jewelry, to corresponding methods, and to a corresponding local sending arrangement.
Patent TW-202319140-A (TW)
Title: Metal plate and wiring implement
Inventor: YOSHIMURA YO
IPC: B21J1/04
Filed: 2022-10-14
Abstract: This metal plate (10) comprises a rectangular base plate (11) and a plurality of side walls (12) rising from a peripheral edge portion (11b) of the base plate (11). The plate thickness of a corner portion (13) formed by two adjacent side walls (12) among the plurality of side walls (12) or formed by one side wall (12) and the base plate (11) is greater than or equal to 40% of a reference thickness of the base plate (11).
Patent TW-202320192-A (TW)
Title: Wire tension adjustment method and wire tension adjustment device
Inventor: TOYAMA TOSHIHIKO
IPC: H01L21/60
Filed: 2022-10-18
Abstract: A wire tension adjustment device (60) adjusts the tension (T) applied to a wire (18) of a wire bonding device (100). The wire tension adjustment device: supplies air to a wire tensioner (40), while the wire (18) is being clamped by a wire clamper (17), so as to detect the height position (H) of a distal end (14f) of a bonding arm (14); and adjusts the flow rate (G) of the air supplied to the wire tensioner (40) on the basis of the detected height position (H), to thereby adjust the tension (T) imparted to the wire (18).
Patent TW-202336861-A (TW)
Title: Seal assembly, semiconductor device manufacturing method, substrate processing method, and program
Inventor: YACHI Masamichi
IPC: H01L21/31
Filed: 2022-11-24
Abstract: Provided is a technology that includes: a seal ring that seals the flanges of a joint; an inner ring that is disposed on the inner circumferential side of the seal ring and regulates movement or deformation of the seal ring toward the inner circumferential side, and an outer ring that is disposed on the outer circumferential side of the seal ring and regulates movement or deformation of the seal ring toward the outer circumferential side. A plurality of spaces for accommodating thermal expansion of the volume of the seal ring are provided between the inner ring and the outer ring in the circumferential direction.
Patent TW-202335645-A (TW)
Title: Controller arrangements for robotic surgical systems
Inventor: LEE JEIHAN
IPC: A61B34/30
Filed: 2022-11-29
Abstract: A controller system for a robotic surgical system can include a first instrument controller comprising a first plurality of motors configured to steer a first attachable robotically controlled medical device, a second instrument controller comprising a second plurality of motors configured to steer a second attachable robotically controlled medical device, and a camera controller comprising a plurality of motors and configured to steer an attachable robotically controlled endoscopic camera.
Patent TW-202327093-A (TW)
Title: Multi gate semiconductor device
Inventor: CHO NAM-KYU
IPC: H01L29/41
Filed: 2022-12-15
Abstract: A semiconductor device includes a first active pattern having a first lower pattern and a first sheet pattern on the first lower pattern. First gate structures include a first gate electrode. A second active pattern includes a second lower pattern. A second sheet pattern is on the second lower pattern. Second gate structures include a second gate electrode that surrounds the second sheet pattern. A first source/drain recess is between adjacent first gate structures. A second source/drain recess is between adjacent second gate structures. A first source/drain pattern extends along the first source/drain recess. A first silicon germanium filling film is on the first silicon germanium liner. A second source/drain pattern includes a second silicon germanium liner extending along the second source/drain recess. A second silicon germanium filling film is on the second silicon germanium liner.
Patent TW-202332771-A (TW)
Inventor: Wang xian-jin
IPC: C12N15/13
Filed: 2022-12-19
Abstract: 本發明涉及CART技術領域，尤其是涉及轉基因免疫細胞及其構建方法和應用。本發明提供了含有三個編碼區的基因。含有該基因的重組核酸、生物材料和轉基因免疫效應細胞能夠編碼三種功能蛋白，三種蛋白的表達使得免疫效應細胞具有多種功能，從而降低實體瘤微環境對免疫效應細胞抑制作用，延長免疫效應細胞的殺傷作用時間；同時增強免疫效應細胞抗腫瘤療效。
Patent TW-202313089-A (TW)
Inventor: LIN YUNG-HSIANG
IPC: A61K36/896
Filed: 2019-10-18
Abstract: 一種金針花萃取物用於製備提升抗醣化活性組成物的用途，金針花萃取物是以溶劑萃取金針花(
         Hemerocallis fulva Linn.)所獲得，溶劑為水、醇、或醇水混合物。
Patent TW-202329939-A (TW)
Title: Salt form and crystal form of complement factor b inhibitor and preparation method and use thereof
Inventor: LUAN LIN-BO
IPC: A61K31/40
Filed: 2023-01-18
Abstract: The present disclosure belongs to the field of medicine, and specifically relates to a pharmaceutically acceptable salt form, crystal form, preparation method and use of the following formula (I) compound:.
Patent TW-202329109-A (TW)
Title: Sram單元
Inventor: Lu chao-chun
IPC: G11C11/41
Filed: 2022-03-09
Abstract: SRAM單元包括多個電晶體、耦接多個電晶體的一組接點、電耦接多個電晶體的字元線、電耦接多個電晶體的位元線和位元線條、電耦接多個電晶體的VDD接線，電耦接多個電晶體的VSS接線。其中，隨著SRAM單元，在不同技術節點的最小特徵尺寸（λ）逐漸變小，由最小特徵尺寸的平方表示之該SRAM單元的面積尺寸相同或基本相同。
Patent UA-56371-A (UA)
Title: "mitsnyi horishok" bitter liqueur
Inventor: Khulapova Halyna Mykolaivna
Filed: 2000-03-27
Abstract: The bitter liqueur contains a walnut infusion and a water-alcohol liquid. The liqueur contains additionally a wine not rectified ethyl alcohol, a lemon alcohol infusion or a lemon ester oil.
Patent UA-48367-A (UA)
Title: Disk-harrow
Inventor: HUKOV YAKIV SERAFYMOVYCH
Filed: 2001-02-19
Abstract: Disk-harrow is composed of front trailed implement, central section (frame) and hinged lateral sections with batteries of disks and hydraulic line with hydraulic cylinders. Disk-harrow is equipped with rear trailed implement hinged with central section (frame), hydraulic line being equipped with a device for shutoff of oil flowing into hydraulic cylinders lifting lateral sections. The rollers are connected to the batteries of disks, lateral sections are additionally connected with central section by buckles, and levers of hydraulic cylinders are connected with lateral sections by buckles made in the form of plates with longitudinal slot.
Patent UA-51134-A (UA)
Title: Ingredient composition for aromatization of strong and soft drinks
Inventor: YALANETSKYI ANATOLII YAKOVYCH
Filed: 2002-01-15
Abstract: An ingredient composition for aromatization of strong and soft drinks contains lemon wormwood, Italian immortelle, thyme, clary sage, rose, lavandin, Origanum, alcohol-wine liquor, fortified wine material or concentrated juice of fruits or berries.
Patent UA-53217-A (UA)
Title: Processor for fast hartley transform of real sequences
Inventor: VOLYNETS VIKTOR IVANOVYCH
Filed: 2002-04-08
Abstract: The proposed processor for fast Hartley transform of real sequences 14 switching units, 4 random-access memories, 3 summing units, 3 subtracting units, a unit for multiplying complex numbers, 2 registers, a read-only memory, 2 counters, and 2 triggers.
Patent UA-56597-A (UA)
Title: Method for producing a composite piezoceramic transducer
Inventor: PAERAND YURII EDUARDOVYCH
Filed: 2002-07-29
Abstract: The proposed method for producing a composite piezoceramic transducer consists in that the soldering of piezoceramic elements and metallic resonators is accomplished concurrently with the polarization of the piezoceramic elements. The polarization voltage pulses are applied in the process of cooling the piezoceramic structure. The amplitude of the polarization voltage pulses shall be less than the breakdown voltage of the piezoceramic material at a maximal temperature. The polarization voltage pulse length shall be less than the time interval within which the polarization current is equal to the value corresponding to the current at the breakdown of the piezoceramic material. The length of the interval between the polarization voltage pulses shall be selected so that the relaxation of the free charges in the piezoceramic material is provided. The polarization voltage pulses are terminated when the temperature of the piezoceramic material is within a range between the Curie temperature and 0 dC.
Patent UA-56640-A (UA)
Title: Matrix for making high-pressure hoses
Inventor: HUPKA BOHDAN VASYLIOVYCH
Filed: 2002-08-06
Abstract: Matrix for making high-pressure hoses is made as a plate, it has a punch with punch-holder, pressing mechanism, pin, buffer, pressure flange, vertical stand, support, M-like levers, forming punches and forming elements.
Patent DO-P2006000008-A (DO)
Title: Terapia combinada para el tratamiento de la diabetes y afecciones relacionadas y para el tratamiento de afecciones que mejoran mediante un incremento de la concentración sanguínea de glp-1
Inventor: CHU ZHI-LIANG
IPC: A61K31/00
Filed: 2006-01-05
Abstract: La presente invención se ocupa de la combinación de una cantidad de un agonista de GPR119 con una cantidad de un inhibidor de la dipeptidil peptidasa IV (DPP-IV) tal que la combinación proporcione un efecto en reducir una concentración sanguínea de glucosa o en aumentar una concentración sanguínea de GLP-1 en un sujeto ma allá de la proporcionada por la cantidad del agonista de GPR119 o la cantidad del inhibidor de la DPP-IV por si solo, y el de dicha combinación para el tratamiento o la prevención de la diabetes y sus afecciones relacionadas o de afecciones que mejoran al aumentar una concentración sanguínea de GLP-1. La presente invención también se relaciona con el uso de un receptor acoplado a una proteína G para detectar secretagogos de GLP-1
Patent DO-P2007000099-A (DO)
Title: Compuestos bicíclicos antidiabéticos
Inventor: GE MIN
IPC: A61K31/421
Filed: 2007-05-14
Abstract: Los compuestos tricíclicos que contienen ácido ciclopropil carboxílico o un derivado de ácido carboxílico (p. ej., amida) condensado con un anillo bicíclico, incluidas las sales farmacéuticamente aceptables y profármacos de las mismas, que son agonistas del receptor 40 acoplado 5 oplado a proteína G (GPR40) y son útiles como compuestos terapéuticos, particularmente en el tratamiento de la diabetes mellitus tipo 2, y de afecciones que a menudo se asocian con esta enfermedad, incluidas la obesidad y los trastornos lipídicos, tales como la dislipidemia mixta o diabética, la hiperlipidemia, la hipercolesterolemia y la hipertrigliceridemia.
Patent DO-P2011000048-A (DO)
Title: Derivados de purina para usarse en el tratamiento de enfermedades alergicas, inflamatorias e infecciosas
Inventor: BIGGADIKE KEITH
Filed: 2011-02-08
Abstract: Se describen compuesto de la formula (I): en la que R1 es alquil C1-6-amino, alcoxi C1-6 o cicloalquiloxi C3-7, m es un numero entero que tiene un valor de 3 a 6, n es un numero entero que tiene un valor de 0 a 4, y las sales de los mismos son inductores de interferon humano. Los compuestos que inducen interferon humano puede ser utiles en el tratamiento de diversos trastornos, por ejemplo, el tratamiento de enfermedades alergicas y otras afecciones inflamatorias, por ejemplo, rinitis alergica y asma, el tratamiento de enfermedades infecciosas y cancer, y tambien pueden ser utiles como adyuvantes de vacunas.
Patent DO-P2016000173-A (DO)
Title: Heteroarilos y usos de estos
Inventor: FLEMING PAUL E
IPC: C07D401/04
Filed: 2016-07-12
Abstract: LA PRESENTE INVENCIÓN PROPORCIONA UN COMPUESTO DE LA FÓRMULA I: I Y SALES FARMACÉUTICAMENTE ACEPTABLES DE ESTE, DONDE X, R1, R2, R3, R4, R5, L1, L2, M Y N SON COMO SE DESCRIBIÓ EN LA MEMORIA DESCRIPTIVA.DICHOS COMPUESTOS SON INHIBIDORES DE VPS34 Y, POR LO TANTO, SON ÚTILES PARA TRATAR TRASTORNOS PROLIFERATIVOS, INFLAMATORIOS O CARDIOVASCULARES.
Patent DO-P2016000282-A (DO)
Title: Anticuerpos humanizados contra la molécula de adhesión celular relacionada al antígeno carcinoembriónico 1 (ceacam1)
Inventor: BEN-MOSHE TEHILA
IPC: G01N33/577
Filed: 2016-10-19
Abstract: Se proporcionan anticuerpos humanizados, capaces de unión específica a moléculas de CEACAM1 humana que contienen mutaciones restauradoras de humano a murino en regiones variables distintas de CDR, y sus secuencias codificadoras de polinucleótidos; también se proporcionan composiciones farmacéuticas que comprenden estos anticuerpos, así como sus métodos de su uso para tratar y diagnosticar cáncer y otras condiciones.