baber/WOPTO huggingface dataset:
Patent IL-176021-A0 (IL)
Title: Stabilized interferon liquid formulations
IPC: A61K38/21
Filed: 2006-05-30
Abstract: Stabilized liquid pharmaceutical composition comprising an interferon (IFN) or an isoform, mutein, fused protein, functional derivative, active fraction or salt thereof, wherein said formulation is a solution that comprises a buffer, a cyclodextrin, an isotonicity agent and an anti-oxidant are described here. Preferably the interferon is interferon beta-1a and the cyclodextrin is HPBCD. These formulations are stable at room temperature, thus bringing the advantage of lower costs for formulation storage and increased safety for the patient with respect to possible “errors” during handling. As a matter of fact, having such formulations stable at room temperature reduces the risk of formation of degradation products potentially responsible for adverse events (e.g. immunogenicity).
Patent IL-184854-A0 (IL)
Title: Aluminum alloy products and artificial aging method
IPC: C22F1/053
Filed: 2007-07-26
Abstract: Aluminum alloy products, such as plate, forgings and extrusions, suitable for use in making aerospace structural components like integral wing spars, ribs and webs, comprises about: 6 to 10 wt. % Zn; 1.2 to 1.9 wt. % Mg; 1.2 to 2.2 wt. % Cu, with Mg (Cu + 0.3); and 0.05 to 0.4 wt. % Zr, the balance Al, incidental elements and impurities. Preferably, the alloy contains about 6.9 to 8.5 wt. % Zn; 1.2 to 1.7 wt. % Mg; 1.3 to 2 wt. % Cu. This alloy provides improved combinations of strength and fracture toughness in thick gauges. When artificially aged per the three stage method of preferred embodiments, this alloy also achieves superior SCC performance, including under seacoast conditions.
Patent MA-21721-A1 (MA)
IPC: B28B23/02
Filed: 1990-01-05
Abstract: The panel is noteworthy in that it is constituted by a prefabricated structure (1) made of reinforced polymer-concrete, one of the faces of the panel receiving over its entire height at least one reinforcement element (E). 
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Patent MA-25819-A1 (MA)
Inventor: KURT MEHMET
IPC: A01K15/02
Filed: 2002-12-13
Abstract: An automatic horse training system includes a horse training device with lateral and rear sides covered by a flexible material. The front side is closed by a locking arrangement thereof, and actuated by a tractor placed front or rear part thereof, and guided by rails or line located upper side of the training device. Electrodes or veterinarian arrangement are placed on different regions of the bodies of the horses for monitoring physical performances thereof by remote electronic signal transmission or alternatively by remote sensing. Movement of the whole mechanical components including stables and corridors in the training system is performed automatically.
Patent MA-26989-A1 (MA)
Title: Derives de pyridine inhibiteurs de metalloproteinases de matrice
Inventor: BARVIAN NICOLE CHANTEL
IPC: A61P/
Filed: 2003-08-05
Abstract: DEPOSANT Société dite : WARNER-LAMBERT COMPANY LLC REVENDICATION DE PRIORITES US	14 Février 2001	60/268,781 Voir en annexe le titre de l'invention et le texte de l'abrégé Dérivés de pyridine inhibiteurs de métalloprotéinases de matrice Des inhibiteurs sélectifs de MMP-13 sont des dérivés de pyridine de formule (I) ou un de leurs sels pharmaceutiquement acceptables, formule dans laquelle : R1 et R2 représentent indépendamment un atome d'hydrogène, un groupe halogéno, hydroxy, alkyle en C1 à C6, alkoxy en C1 à C6, alcényle en C2 à C6, alcynyle en C2 à C6, NO2, NR4R5, CN ou CF3 ; E représente indépendamment un atome de O ou S ; A et B représentent indépendamment un groupe OR4 ou NR4R5 ; R4 et R5 représentent indépendamment H, un groupe alkyle en C1 à C6, alcényle en C2 à C6, alcynyle en C2 à C6, (CH2)n-aryle, (CH2)n-cycloalkyle ou (CH2)n-hétéroaryle, ou bien R4 et R5, lorsqu'ils sont pris conjointement avec l'atome d'azote auquel ils sont fixés, complètent un noyau tri- à octogonal, contenant des atomes de carbone et contenant facultativement un hétéroatome choisi entre O, S et NH, facultativement substitué ou non substitué ; n a une valeur de 0 à 6.
Patent MA-27814-A1 (MA)
Title: Derives de pyridazinones en tant qu'inhibiteurs de gsk-3beta
Inventor: HOELDER SWEN
IPC: C07D401/12
Filed: 2005-05-17
Abstract: La présente invention concerne des nouveaux dérivés de pyridazinones de formule générale (I) dans laquelle A est A1 ou A2 ; R est C1-C10-alkyle, aryle, aryl-(C 1-C10-alkyl)- hétéroaryle. hétéroaryl-(C1-C10-alkyl)-, hétérocyclyle, hétérocyclyl-(C 1 -C10-alkyl)-, C3-C10-cycloalkyle, polycycloalkyle, C2-C10-alcényle ou C2-C10-alcynyle non substitué ou au moins monosubstitue, Ar est aryle or hétéroaryle non substitué ou au moins monosubstitue ;
Patent MA-28044-A1 (MA)
Inventor: URSEL VALERY
IPC: B01D21/00
Filed: 2006-03-16
Abstract: The two plates (2, 3) have the same corrugated profile and are fixed together in linking zones defining a plane of symmetry (P) for the tubes (4) defined by the plates. The crests and valleys of the corrugations are inclined with respect to a first edge of the plate by a non-zero angle and which surrounds with the other plate inclined decantation tubes : The angle of inclination alpha is between 45 and 65 degrees., preferably between 55 and 60 degrees. The crests and valleys are trapezoidal in form so the decantation tubes have a hexagonal section. The crests (2A, 3A) and valleys (2B, 3B) have identical shapes and the two plates are symmetrical with one another about the plane of symmetry of the tubes. The two plates are identical and are rectangular, with the tubes rectilinear over their whole length. An independent claim is made for a decantation block made of several plates of which at least one pair are as described above. The block has at least two modules joined together so the modules together define other tubes of the same section as the tubes in each module. The modules are identical. The block is in the form of a rectangular parallelepiped, with the plates parallel to one of the faces of the block. The plates extend perpendicular to the smallest dimension of the block and the block is arranged so that the plates are vertical and the first edge horizontal. The block has seating elements by which the block can be held suspended from or rested on a fixing system. At least two identical blocks can be juxtaposed so the tubes of one block are the extension of the tubes in the other. The block is placed near a vessel wall to which the plates are perpendicular, leaving a space between the wall and the block. The tubes have a hydraulic diameter of between 40 and 100 mm and their length is between 15 and 30 times their diameter.
Patent MA-28155-A1 (MA)
Title: Composition pharmaceutique
Inventor: AHLHEIM MARKUS
IPC: A61K9/16
Filed: 2006-05-11
Abstract: L'invention concerne des microparticules comprenant un analogue de somatostanine incorporé dans une matrice polymère biocompatible pharmaceutiquement acceptable à libération prolongée et des compositions pharmaceutiques comprenant lesdites microparticules.
Patent MA-20150195-A1 (MA)
Title: Procede de fabrication de bio-film par utilisation de plymere agro-ressource comme emballage intelligent pour l'agroalimentaire
Inventor: BENHIMA REDOUANE
IPC: C08L5/08
Filed: 2013-10-10
Abstract: La présente invention concerne le procédé de fabrication de bio film composites utilisables dans le domaine de l'emballage agroalimentaire à base de bio polymère et de molécules biologiquement actives liés par des liaisons covalents de type imine (c=n); le matériaux est renforcé par différents charges inorganique (argile: montmorillonite; sépiolite, hallyosite,...) ou organique (amidon, fibre de cellulose, nanocelluose...). Ces biomatériaux présentent des propriétés antibactériennes et antifongiques vis-à-vis des souches bactériennes et fongiques indicatrice de contamination des produits alimentaires.
Patent MA-20150297-A1 (MA)
Title: Composition de traitement de minerais de phosphate
Inventor: DA SILVA WAGNER CLAUDIO
IPC: B03D103/06
Filed: 2013-08-20
Abstract: L'invention concerne un agent de flottation pour minerai de phosphate, qui comprend au moins un acide gras et au moins un sarcosinate de formule (i), dans laquelle r est un groupe alkyle c
Patent UY-26362-A1 (UY)
Title: Nuevos derivados de la 2, 4, 6 - trione-pirimidina
Inventor: MENTA ERNESTO
IPC: C07D403/12
Filed: 2000-09-29
Abstract: Compuestos de la fórmula (I) en la cual r1 representa un radical fenoxilo, feniltio, fenilsufinilo, fenilsulfonilo, fenilamino o fenilmetilo, substituido o sin substituir y r2 representa un radical arilo o heteroarilo, opcionalmente substituido, con actividad como inhibidor de la metalo- proteinasa.
Patent UY-26644-A1 (UY)
Title: Pequenas esferas o glóbulos que contienen estavudina y permiten la liberación controlada de la misma
Inventor: ABRAMOWITZ ROBERT
Filed: 2001-03-29
Abstract: Formas de dosificación prolongada de estavudina que comprenden pequenas esferas o glóbulos formados por extrusión - formación preparadas de una mezcla seca de estavudina, un agente formador de pequenas esferas o glóbulos, un diluyente adecuado y una cantidad estabilizadora de estearato de magnesio y recubiertos con un sellado y otro recubrimiento de liberación modificada. También se incluye en el alcance de la invención cápsulas de gelatina rígida que contienen, además de las pequenas esferas o glóbulos de estavudina, pequenas esferas o glóbulos similares que contienen otros agentes terapéuticos utilizados para tratar infecciones retrovirales.
Patent UY-27579-A1 (UY)
Title: Derivados de ciclohexano sustituidos
Inventor: ACKERMANN JEAN
IPC: A61K31/505
Filed: 2002-12-11
Abstract: La presente invención se refiere a compuestos de fórmulas (I) en donde 1, A2, A3, A4, A5, A6, A7, A8, A9, A10, U, V, W, M, N, y P son como se definen en la descripción y reivindicaciones, y sales farmacéuticas aceptables de los mismos. Los compuestos son útiles para el tratamiento y/o prevención de enfermedades que están asociadas con 2,3- oxcidoescualenolanosterol ciclasa tal como hipercolesterolemia, hiperlipemia lanosterol ciclasa tal como hipercolesterolemia, hiperlipemia, artetiosclerosis, enfermedades vasculares, micosis, infecciones de parásitos, cálculos biliares, tumores y/o trastornos hiperproliferativos, y tratamientos y/o prevención de tolerancia a la glucosa disminuida y diabetes.
Patent ES-156443-A1 (ES)
Title: Aparato para homogenizar y esterilizar lna leche
Filed: 1942-03-18
Abstract: Aparato para homogenizar y esterilizar leche y lacticinios en el cual la esterilización integral de la leche se efectúa mediante ozono aire ozonizado u otro gas equivalente sin acción nociva para la leche; caracterizado por el hecho de que las dos operaciones homogenización y esterilización se efectúan simultáneamente a la temperatura del ambiente llegando la leche a un estado de difusión o de división tan avanzado que las partículas de grasa que contiene no puedan ya separarse del suero (homogenización) y porque el gas esterilizante se mezcla con leche así atomizada sin presión apreciable para que no exista gas retenido dentro de la leche líquida comprendiendo el aparato una cámara inferior dentro de la cual la mezcla gaseosa y en parte líquida de leche y de gas pasa por tabiques de choque con el fin de asegurar la condensación de la leche y la esterilización final de dicha leche líquida por el gas esterilizados saliendo la leche líquida por la parte baja de dicha cámara mientras que el gas se escapa a la armósfera.
Patent ES-173501-A1 (ES)
Title: PROCEDIMIENTO E INSTALACIoN PARA LA PREPARACIoN DE CAFÉ SIN CAFEiNA
IPC: A23F5/20
Filed: 1946-05-08
Abstract: Procedimiento e instalación apra la preparación de café sin cafeína por el tratamiento del café en grano por medio de una sustancia adecuada para disolver la cafeína caracterizándose por el hecho de que la extracción se realiza en un dispositivo consistiendo en un recipiente destinado a recibir el café y que está casi completamente lleno de un disolvente en cuyo fondo está empalmado un tubo conectado a la parte superior del recipiente por encima del nivel del líquido en cuyo tubo se introduce un gas a presión a una altura determinada lo cual provoca la puesta en circulación de la solución disolvente y del café en el recipiente y en el tubo de empalme sometiéndose el café en grano a un cambio periódico de presión.
Patent ES-179207-A1 (ES)
Title: Procedimiento para el tratamiento de fibras de vidrio
IPC: C03C25/10
Filed: 1947-08-05
Abstract: Procedimiento para el tratamiento de las fibras de vidrio con vistas a su coloración y a la mejora de sus propiedades consistente en recubrir las fibras de vidrio preferentemente durante la operación de formación por medio de una materia susceptible de formar una película teñida o coloreada en solución acuosa insolubilizando luego la tintura o la materia colorante de dicha película.
Patent ES-181850-A1 (ES)
Title: DISPOSITIVO DE DEMODULACIoN POR DESPLAZAMIENTO DE IMPULSOS EN SISTEMAS DE MODULACIoN SIMPLE
Filed: 1948-01-24
Abstract: En un sistema de impulsos múltiples en el cual la modulación se efectúa por desplazamiento de los impulsos de duración constante alrededor de su posición media, constando el canal de referencia de dos impulsos que no llevan el mensaje y que tienen una separación menor que cualquier otra separación existente en el sistema, siendo seguido cada par de impulsos de referencia, por un grupo de impulsos asignados cada uno a un canal portador de mensaje, un dispositivo detector que comprende medios para cambiar las señales recibidas en impulsos de igual duración medios para superponer los dos impulsos y formar un impulso único, medios para distribuir el referido impulso en circuitos particulares a cada canal, medios en cada circuito de canal, para superponer el referido impulso único sobre el impulso portador de mensaje y obtener un impulso de una duración proporcional a la modulación, medios para obtener de este último impulso una corriente que tenga una amplitud proporcional a la modulación, medios para bloquear el dispositivo para la distribución del impulso que resulta de la superposición de los impulsos de referencia después del último impulso de referencia, por un período igual al intervalo que separa al último impulso de referencia de un grupo, del primer impulso de referencia del grupo siguiente.
Patent ES-190792-A1 (ES)
Title: Perfeccionamientos en grifos esféricos accionados axialmente
Filed: 1949-12-12
Abstract: Perfeccionamientos en grifos esféricos accionados axialmente caracterizados porque permite la fácil apertura y cierre de la salida de los líquidos de los grifos volantes de la mano que sostiene el cuerpo del grifo merced a la simple maniobra de una palanca.
Patent ES-294323-A1 (ES)
Title: Method and apparatus for the continuous introduction of liquid into a staple fiber web or the like
IPC: D01G29/00
Filed: 1963-11-30
Abstract: Apparatus for continuously liquid treating a band or sliver of staple fire comprises a guide or support for the band or sliver and means for forcing the liquid through the fibres. As shown a flat web 11 coming from a drafting arrangement passes to a guide 10 whereby it is guided into tubular form (see Fig. 4, not shown), a tube 12 carrying the treatment liquid under pressure being arranged to lie in the centre of the tube of fibres. The tubular web passes via a nozzle 14 to a tapering wire spiral 15 between the turns of which liquid may be expelled from the centre of the web. The web next passes between calender rolls 5 having side confirming plates 19 to have excess liquid expelled therefrom and to be smoothed. The expelled liquid may be collected and pumped to the pressure vessel which feeds tube 12. The spiral 15 which is surrounded by a spray guard 16 is preferably coated with an antifriction material. Alternative guides to replace the spiral 15 comprise an internally threaded tube of tapering internal diameter or a stack of discs having progressively smaller holes therein, liquid outlet channels being formed in the surfaces of the discs. In an alternative arrangement the web passed directly from the drafting roller to a wire spiral guide having an oval cross-section at its upper end the largest diameter of the oval tapering so that the cross section becomes circular at the lower end. A hood to which pressurized liquid is led covers one side of this spiral and liquid is thus forced through the fibres contained therein.
Patent ES-322768-A1 (ES)
Title: Electronic oven
IPC: H05B6/80
Filed: 1966-02-08
Abstract: A microwave source, e.g. a magnetron 32, is matched to waveguides 41, 42 feeding a microwave oven 19 by means of a progressive variation in the impedance of the waveguide 40 in the neighbourhood of the T-junction with the co-axial feeder 38. This may take the form of arcuate inserts disposed against the narrow sides of the waveguide 40 on either side of the antenna 39 whereby the broad dimension of the waveguide is reduced to the diameter of the outer conductor 38 (Figs. 2, 3, not shown). The oven is fed with generally ellipticallypolarized microwave energy by means of mutually-orthogonal oblique slots 43, 44 covered with insulative tape 60. The magnetron 32 is cooled and the oven ventilated by means of a fan 35. Apertures 63 are provided in the wall of housing 10 and further apertures (not shown) in the wall 22 of the oven to allow circulation of air. A closure 26 for the oven comprises a layer 30 of dissipative material. The closure carries an arm, (65 Fig. 8, not shown) which short-circuits a pair of power switch contacts (68) outside the oven when the oven is closed. Food to be heated is supported upon a revolving table 55 of low-loss dielectric material.
Patent ES-336000-A1 (ES)
Title: Preparation of N-Aminoalkyl-2-Alkoxy-5-Halogenobenzamides and Benzimide Acid Derivatives for use in such Preparation
IPC: C07C233/00
Filed: 1967-01-16
Abstract: Novel benzamidines of the general formula wherein R1 is an alkylene radical R11 is a mono- or di-alkylamino group in the latter of which the alkyl radicals may be joined to form a cyclic group, the carbon atom chain of which may be interrupted by one or more nitrogen, oxygen or sulphur atoms R 1 is a C 1-5 alkoxy group R 2 is a nitro or amino group and X is a halogen atom, and acid addition salts thereof are prepared by reaction of a nitrile of the general formula with an alcohol of the general formula R 3 OH, wherein R 3 is a C 1-5 alkyl group, in the presence of an acid catalyst, followed optionally by salification, and reaction of the resulting novel alkyl ester of a benzimide acid of the general formula or an acid addition salt thereof with an amine of the general formula H 2 NR1R11, followed optionally by salification. The novel benzamidines of the first general formula above or acid addition salts thereof may be hydrolysed, followed optionally by salification, to form N-aminoalkyl-2-alkoxy-5- halogeno-benzamides of the general formula and acid addition salts thereof.
Patent ES-337421-A1 (ES)
Title: Panel mount fastener socket for and with a stud
IPC: F16B21/07
Filed: 1967-03-01
Abstract: A fastener socket for receiving a stud 3 has means for mounting the socket in a panel aperture, the socket being folded up from sheet metal and comprising a short entrance portion defining an opening of generally square shape, the entrance portion having a longitudinal open seam 9 at the corner, the four sides of the entrance portion at one end being formed with respective elongated extensions 12 defining cantilever springs supported by the entrance portion, free end portions of the extensions being turned in to define a stud engaging portion presenting a generally square opening smaller than that of the opening defined by the entrance portion. In the construction shown, the means for mounting the socket in the panel aperture comprises flanges 10 and detents 14 cut out of each extension 12. The stud shown is of octagonal cross-section, alternate sides being provided with slots 7 of triangular section, each slot having a side remote from the head extending perpendicular to the stud length and a side adjacent the head inclined inwardly in a direction away from a head 6 of the stud the other sides of the stud are flat. The stud is engageable with the socket by pushing it into the socket through the entrance portion so that the free end portions 13 of the extension engage in slots 7. It is released from the socket by rotating it through 45 degrees which brings the flat sides into engagement with the portion 13 after which it can be withdrawn axially. The stud can alternatively be provided with a screwthread in which case the free end portions of the extensions are each provided with an arcuate concave profile 18 for engaging the screw threads the extensions are also inclined at an angle corresponding to the angle of the screw threads and the end portions are suitably staggered.
Patent ES-342907-A1 (ES)
Title: N'-substituted n-arylsulfonyl urea
IPC: C07D221/22
Filed: 1967-07-11
Abstract: A novel compound (and inorganic and organic salts thereof) of the formula is prepared by the interaction of 2-aza-bicyclo- [2,2,2]-octane or an alkali metal derivative thereof and p-nitrophenyl-sulphonyl isocyanate or a reactive functional derivative of a carbamic acid of formula p-R-phenyl-SO 2 NH.COOH, wherein R represents an amino group or a group which can be converted to an amino group by hydrolysis reduction or reductive cleavage, and thereafter if necessary hydrolysing or reducing the product so obtained. Pharmaceutical preparations have a hypoglycaemic action, contain as active ingredient the above novel compounds and may be administered orally or parenterally.
Patent ES-343918-A1 (ES)
Title: Injection syringe
IPC: A61M5/34
Filed: 1967-08-08
Abstract: In a cartridge-type hypodermic syringe for receiving an ampoule 2 with a puncturable diaphragm closure 9 (12 Fig. 3), screwthreads 13, 17 of opposite hands secure the holder 3 of a double-pointed needle 4 and a needle cap 5, respectively, to the syringe body and a projection 15 on the holder engages the cap to prevent relative rotation of the holder and cap so that as the cap is unscrewed for removal, the needle is moved axially in the opposite direction to puncture the diaphragm. The projection 15, which extends axially from the holder, has one or more plane faces parallel to the axis, e.g. the projection is of square section, and engages a correspondingly shaped cavity 16 in the cap. The ampoule 2 may be mounted on a piston 10 by its closure 9 so that the contents are discharged through the needle as the ampoule is pushed further on to the piston. Alternatively the ampoule is contained in the syringe body (Fig. 3) and its contents are expelled by a plunger applied to a rear closure in conventional manner.