baber/WOPTO huggingface dataset:
Patent PT-924299-E (PT)
Inventor: SAILLAND ALAIN
IPC: C12N1/21
Filed: 1992-03-04
Abstract: A new ADN transit peptide sequence comprises at least one coding sequence for the transit peptide from a plant gene encoding an enzyme located in plastids, the mature part of the N-terminal sequence of the plant gene coding for an enzyme located in plastids, and/or a sequence coding for a second transit peptide from a plant gene coding for an enzyme located in plastids. Independent claims are also included for the following: (1) a chimeric gene useful in plants to confer herbicidal resistance having an EPSPS target comprising a promoter region, a transit peptide region (as above), a sequence coding for resistance to glyphosate and a polyadenylated signal region not 3' translated; (2) a process for the construction of the above chimeric gene comprising isolating at least 2 regions of the transit peptide and at least part a sequence of the mature plant plastid genes to achieve at least one sequence coding for glyphosate resistance and a polyadenylated signal region therefore altogether providing plant resistance; (3) a vector for the transformation of the plant comprising the above chimeric gene; (4) a transformed plant cell containing the above chimeric gene; (5) a transformed plant with an improved resistance to herbicides having an EPSPS target obtained using the above cell; (6) a transformed plant with an improved resistance to herbicides having an EPSPS target stems from crossing the above plants; (7) a process for obtaining hybrid cell lines having glyphosate resistance using the above plants as parent plants; and (8) a process for treating the above plants comprising applying a herbicide having an EPSPS target.
Patent PT-1028940-E (PT)
Title: Process to produce oxazolidinones
Inventor: PEARLMAN BRUCE A
IPC: C07D263/24
Filed: 1998-10-13
Abstract: The present invention includes a number of novel intermediates such as the (S)-secondary alcohol of formula (VIIIA) X 2 -CH 2 -C*H(OH)-CH 2 -NH-CO-R N  and processes for production of pharmacologically useful oxazolidinones.
Patent PT-979133-E (PT)
Inventor: ALLINGHAM PAUL
IPC: B01D46/02
Filed: 1998-10-22
Abstract: The disclosed apparatus is a filter bag cage which is modularly constructed from end caps, circumferential rings (circular or other shapes), and longitudinal wires which are individually manufactured with fastening joints to allow for later assembly. These components may be subsequently shipped and stored as an unassembled bundle and not assembled until reaching the point of use.
Patent PT-1175664-E (PT)
Inventor: LAUPER KARIN BUSCH
IPC: G07F7/02
Filed: 1999-05-03
Abstract: Method for distribution of value codes configured to be cashed in to obtain credit for services subject to charges. The value codes are generated and stored in a database of a value code issuer. A value code is ordered by a customer through transmission of order data, containing at least one monetary amount value, via an order channel, to the value code issuer. A delivery number, linked in the database with the value code, is transmitted via a delivery channel to the customer, and the receipt of the transmitted delivery number is confirmed by the customer through transmission of at least one part of the delivery number via a confirmation channel to the value code issuer. A value, linked in the database to the monetary amount value, is transmitted via a delivery channel to the customer, and a monetary amount value corresponding to at least the monetary amount value linked to the confirmed value code is charged to the customer.
Patent PT-1314436-E (PT)
Title: Antiviral composition comprising interferon in the form of nose drops
Inventor: GAPONYUK PETR YAKOVLEVICH
IPC: A61K9/00
Filed: 1999-09-06
Abstract: The present invention can be used in pharmacology specifically in the preparation of interferon-containing compositions, which are capable of conserving their biological activity and can be administrated intranasally, e.g. in the preparation of nasal drops. This invention essentially refers to an antiviral agent in the form of nasal drops that contains a genetically engineered alpha, beta or gamma interferon with a viscosity of (1,1 - 30.0) * 10 Pa*s, a biocompatible polymer and a buffer mixture. The agent may further include an antioxidant, and the ingredients are contained in the following amounts per ml buffer mixture: 1,000 to 500,000 IU of genetically engineered interferon; 0.005 to 0.714 g of biocompatible polymer; and 0.0001 to 0.0008 g of an antioxidant. Trilon B is used as the antioxidant, whereas polyvinilpyrrolidone and/or polyethylene oxide is (are) used as the biocompatible polymer(s) at polyvinilpyrrolidone/polyethylene oxide ratio is 1:1 - 50.
Patent PT-1126867-E (PT)
Inventor: GEORGE JACOB
IPC: A61K38/17
Filed: 1999-09-30
Abstract: An immunological oral tolerance-inducing composition for prevention and/or treatment of atherosclerosis, comprising an active component selected from the group consisting of modified low density lipoprotein, oxidized low density lipoprotein (Ox LDL), heat shock protein 60/65 (HSP 60/65), beta2-glycoprotein-1(?2GP-1), functional derivatives thereof and mixtures thereof, in combination with a pharmaceutically acceptable carrier for oral administration.
Patent IE-35956-L (IE)
Title: Fused ring indole derivatives
IPC: C07D233/04
Filed: 1972-01-08
Abstract: 1366133 Fused-ring indolines JOHN WYETH & BRO Ltd 14 Dec 1971 [11 Jan 1971 2 Sept 1971 6 Dec 1971] 1250/71 40959/71 and 56467/71 Heading C2C The invention comprises compounds of formula and their acid addition or quaternary ammonium salts, wherein R is OH (or its C 1-6 alkyl, aryl- C 1-6 -alkyl or tetrahydropyracyl ether, or ester derivative); R<SP>1</SP> is aryl (mono- or bicyclic), C 1-6 alkyl (possibly aryl- or amino-substituted), or up to C 6 alkenyl or alkynyl; or RR<SP>1</SP> is O=, or (when n is 1) its alkylene or di-(C 1-6 alkyl) ketal; R<SP>2</SP>, R<SP>5</SP> are each H, OH, halogen, NH 2 (possibly mono- or di-C 1-6 -alkyl substituted), or C 1-6 alkyl, haloalkyl or alkoxy, or (when RR<SP>1</SP> is O = or a ketal thereof) NO 2 ; R<SP>3</SP>, R<SP>4</SP> are each H or C 1-6 alkyl, or R<SP>3</SP> is H and R<SP>4</SP> is OH; n is 0-2; and R<SP>6</SP> (present only when the optional bond represented by the broken line is absent) is H, acyl, C 1-6 alkyl (possibly substituted by aryl, or up to C 6 alkenyl or alkynyl. In Examples, (1) the compounds containing the optional bond are prepared thus: (a) the ethylene ketals (A) by reductive ring-closure of corresponding 1-cyanoalkylizatin-3-ethyleneketals; (b) the ketones (B) by either hydrolysing ketals (A), or ring-closing corresponding 2-halophenyl/heterocyclyl ketones (C); (c) the alcohols by reacting ketones (B) with R<SP>1</SP>Mg-halide or R<SP>1</SP>-Li; (d) halogenation, nitration or esterification; ... (2) the compounds not containing the optional bond are prepared by reducing those containing it, possibly in the form of a quaternary ammonium salt. Ketones (C) are prepared by oxidizing the corresponding alcohols. 1 - (2 - Cyanoethyl) - 5 - methoxyizatin, bromo-tert-butyl cyanide and isatin-3-ethyleneketal are also prepared. Therapeutic compositions for oral or parenteral administration comprise compounds of the above formula (other than those where RR<SP>1</SP> is O= or a ketal thereof), which have antidepressant, antiinflammatory, antihistaminic, cardiovascular, diuretic and/or hypoglycaemic activity.
[GB1366133A]
Patent IE-860134-L (IE)
Title: Imidazole derivatives.
IPC: A61K31/66
Filed: 1986-01-16
Abstract: Compounds of formula (I): <IMAGE> (I) [wherein: m is 1-3; A and B are oxygen or sulfur; and one of R1 and R2 is C10-C22 alkyl and the other is a group of formula (II). <IMAGE> (II) where: n is 2 or 3; and -NR3R4R5 is an amino group] and salts thereof are effective anti-cancer agents.
[US4794183A]
Patent IE-790157-L (IE)
Title: Therapeutic agents
IPC: C07C67/00
Filed: 1979-01-30
Abstract: The invention is related to a process for the treatment of humans suffering from undesired urotoxic side effects caused by cytostatically active alkylating agents administered to them against malign tumors, comprising administering a pharmacologically acceptable salt of a dithiodi-(alkane sulfonic acid) having the general formula <IMAGE> to the human treated with the cytostatically active alkylating agent, in an amount ranging from 20% of the weight of the alkylating agent to the highest tolerated dosage of the salt of the dithiodi-(alkane sulfonic acid), simultaneously or separately in combination with the alkylating agent.
[US4218471A]
Patent IE-790165-L (IE)
Title: Oxabicyclo £3.1.0| hexanes
IPC: C07C67/00
Filed: 1979-01-30
Abstract: The invention provides compounds of the formulae: <CHEM> in which R is hydrogen or CX3, each X, which is the same as or different from the other, is a chlorine or bromine atom, R<1> is lower alkyl or lower alkoxy, R<2> is hydrogen, lower alkoxycarbonyl or lower alkanoyl, and R<3> is hydrogen or lower alkoxycarbonyl. The compounds of Formula III are made by intramolecular carbenoid cyclization of compounds of Formula II; the compounds of Formula II are made from compounds of Formula I, e.g. by treatment with azide followed by a base; the compounds of Formula I are prepared by reacting an alcohol of formula: <CHEM> with a hydrazone. Those compounds of Formula I in which R is CX3 can be converted to a compound of the formula: <CHEM> in which the carboxy and dihalovinyl groups are cis with respect to each other, which are insecticidal, by treatment with certain metals in selected solvents.
Patent IE-890206-L (IE)
Title: Immunotoxins from barley toxin
IPC: C07K16/00
Filed: 1989-01-24
Abstract: A process for making a conjugated immunotoxin by the steps of reacting barley toxin with a linking agent to introduce into the barley toxin not more than about two linking groups per barley toxin molecule to produce a bioactive, conjugable barley toxin, and reacting the conjugable barley toxin with an activated antibody to produce a bioactive immunotoxin.
[EP0327169A2]
Patent IE-840361-L (IE)
Title: Formation of fibre felts
IPC: D04H1/4209
Filed: 1984-02-16
Abstract: 1. A method of forming a felt of fibres in which the fibres are formed from a material which is in the drawable state, this material being carried over the peripheral surface of one or more wheels to which a rotary movement is imparted and from which the fibres become detached and are thrown into a gaseous current which is directed transversely of the direction in which the fibres are thrown and along the peripheral wall of the wheel or wheels, the fibres thus formed, entrained by the gaseous current, being carried into a receiving chamber in which the base is constituted by a perforated conveyor, the gaseous current carrying the fibres crossing the conveyor, the fibres becoming deposited on the conveyor in order to form the felt, the method being characterized in that one or a plurality of additional gas jets are created on either side of the gaseous current carrying the fibres substantially in the same direction as that of the current, these additional jets being emitted along lateral walls bordering the perforated conveyor.
Patent IE-870377-L (IE)
Title: Fungicidal composition
IPC: A01N43/653
Filed: 1987-02-13
Abstract: Combinations of the fungicides propiconazol and fenpropidin, which are both inhibitors of ergosterol biosynthesis, exhibit a synergistically enhanced activity against fungi. The active components may also be applied individually in immediate succession.
Patent IE-34226-L (IE)
Title: Sterile ampicillin suspensions
IPC: C07D499/68
Filed: 1970-05-26
Abstract: 1316625 Compositions containing ampicillin trihydrate E R SQUIBB & SONS INC 29 May 1970 [6 June 1969] 26124/70 Heading A5B [Also in Division C2] An antibacterial composition comprises sterile ampicillin trihydrate having a particle size in the range 5 to 50 microns, at least 50% of the particles of the ampicillin trihydrate having a particle size in the range 20 to 50 microns in admixture with a suspending agent e.g. sodium carboxymethylcellulose, and a dispersing agent e.g. lecithin, the composition being admixed with water before injection. Stable, long-acting injectable compositions comprise a suspension of the above ampicillin in water preferably containing an acidic buffer and having a pH from 4.0 to 7.0.
[GB1316625A]
Patent IE-860807-L (IE)
Title: Bone implant of fiber reinforced resin
IPC: A61F2/30
Filed: 1986-03-26
Abstract: In a method of producing implants of bone replacement material from resin reinforced with carbon fiber at least the fibers in the parts of the surface which are to come into contact with the bone tissue are exposed by mechanical treatment. This provides for an improved unification of the bone with the implant. The fibers at the surface may be fibers of a fabric which is wrapped around a basic member shaped to conform to the desired implant.
[US4714467A]
Patent IE-39226-L (IE)
Title: Desulphurisation of asphaltene-containing oils
IPC: B01J23/88
Filed: 1974-04-18
Abstract: 1458751 Hydrodesulphurization of heavy oils UOP Inc 29 April 1974 [30 April 1973] 18605/74 Heading C5E Asphaltene - containing hydrocarbonaceous oils are desulphurized by reacting with hydrogen in the presence of a catalyst comprising alumina, a sulphided Group VIb component and a sulphided Group VIII component and having a catalyst particle density of 1-05 to 1 30 g./c.c. The catalysts used in examples can contain 2 wt. per cent Co and 8 wt. per cent Mo and can be prepared from a hydrosol having an Al/Cl ratio of 1 09 to 1 27 by forming spheres by the oil drop method, drying, calcining, impregnating, reducing and sulphiding.
[GB1458751A]
Patent IE-820863-L (IE)
Title: Process of production of organic dithio-acids and their¹applications.
IPC: B03D1/00
Filed: 1982-04-14
Abstract: Process for the preparation of an organic dithio-acid by reaction of the corresponding dithio-ester and an alkali metal or alkaline earth metal hydrosulphide in a solvent in the presence of an excess of H2S and treatment with a mineral acid. The dithioic acids so obtained can be utilized as collectors for the flotation of minerals.
[US4455262A]
Patent IE-39549-L (IE)
Title: Ureido-aryl cephalosporins ureido-phenylglycines
IPC: A61P31/04
Filed: 1974-05-07
Abstract: Cephalosporins with a alpha -amino-(ureidophenyl)acetamido substituent at position 7 are prepared by acylation of a 7-aminocephalosporin with a derivative of alpha -amino-p(or m)-ureidophenylacetic acid. These compounds are antibacterial agents.
[US4007173A]
Patent IE-43845-L (IE)
Title: 4-thia-1-azabicyclo [4.2.0] oct-2-ene derivatives
IPC: C07D513/04
Filed: 1976-05-05
Abstract: Compounds of the formula I in which R and E have the meaning stated in Claim 1 are antibiotics which are effective against Gram-positive and Gram-negative bacteria. They are prepared by N-acylation of compounds of the formula II in which R<2> is hydrogen or a carboxyl protective group with compounds of the formula RX' in which X' has the meaning stated in Claim 1, and elimination of any carboxyl protective group present. During the reaction, intermediate protection of the sensitive substituents present in the radical R is also possible. The carboxylic acids of the formula II in which E is bromomethyl are prepared by bromination of compounds of the formula IV-b in which the substituents have the meaning stated in Claim 25 with a compound which provides bromine free radicals in the presence of an initiator which provides free radicals, with subsequent elimination of the amino protective group, or if E in the formula IV-b is a lower alkanoyloxymethyl group, by reaction of a compound of the formula VIII in which the substituents have the meaning stated in Claim 29 with a salt of a lower alkanecarboxylic acid and subsequent elimination of the amino protective group. <IMAGE>
[GB1553429A]
Patent FI-851544-L (FI)
Inventor: ANDREASSON KURT
IPC: G06K17/00
Filed: 1985-04-18
Abstract: when recording an inventory, a video-camera having a microphone and optics making possible total views, as well as detail views on a larger scale of the individual objects is used. When the recording is terminated the cassette (22) is sealed by means of a cylindrical body (32) introduceable in a cylindrical passage (27) in the cassette casing, the body being provided with at least one extending lip (38) engaging an opening in the side wall defining the passage (27).The lip may be forced outwards by depressing a piston (39) in the body (32). The piston is provided with at least one cam, which catches the lip (38) and will be retained thereby.An arm (34) directed sidewardly from the body (32) carries a member (335) at its distal end adapted to lock the lid (24) of the cassette.
Patent IE-34501-L (IE)
Title: Sulphonyl-imidazolidines
IPC: C07D233/46
Filed: 1970-09-03
Abstract: Compounds of the class of 1-[p-(acetoacetamidoalkyl)-phenylsulfonyl]-2-imino-imidazolidines and the pharmaceutically acceptable acid addition salts thereof, have hypoglycemic activity; the compounds are active ingredients of pharmaceutical compositions and can be used for the treatment of diabetes mellitus; a typical embodiment is 1-[p-(2-acetoacetamidoethyl)-phenylsulfonyl]-2-imino-3-methyl-imidazol idine.
[US3708493A]
Patent IE-45249-L (IE)
Title: Dibenzopyran derivatives
IPC: A61K31/352
Filed: 1977-07-05
Abstract: Reaction of a 5-substituted resorcinol with optically active apoverbenone in the presence of aluminum chloride affords an optically active trans-1-hydroxy-3-substituted-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9 H-dibenzo[b,d]pyran-9-one.
[US4075230A]
Patent IE-44351-L (IE)
Title: Ocular insert
IPC: A61K9/22
Filed: 1976-09-22
Abstract: 1526476 Ocular insert ALZA CORP 22 Sept 1976 [28 Oct 1975] 39320/76 Heading A5B Ocular inserts for treating dry eye comprise a therapeutic agent (a) capable of causing osmotic flow of water from the interstitial fluid to the tear film, (b) biologically compatible with the eye and (c) having no systemic or topical pharmacological or physiological effects at the dosage used except to induce aqueous flow, contained within a polymer body for insertion in the cul-de-sac of the eye, the polymer body releasing the therapeutic agent over a period of time and in sufficient quantity to produce the desired effect of inducing the said aqueous flow.
[GB1526476A]
Patent IE-812146-L (IE)
Title: Ethenylimidazole derivatives
IPC: C07D233/94
Filed: 1981-09-16
Abstract: The invention relates to new ethenylimidazoles of the formula <CHEM> in which n is 0, 1 or 2, R1 represents a halogen atom, a trifluoromethyl group or an alkyl or alkoxy group with at most 6 carbon atoms, the two substituents being the same or different when n is 2, R2 represents an alkyl group with 1 to 6 carbon atoms, an alkenyl group with 2 to 4 carbon atoms or a cycloalkyl group with 3 to 6 carbon atoms, R3 represents a hydrogen atom, an alkyl group with 1 to 6 carbon atoms or an alkenyl group with 2 to 4 carbon atoms and R4 represents a hydrogen atom, an alkyl group with 1 to 6 carbon atoms or a nitro group, and their acid addition salts. Other features of the invention are  - processes for the preparation of compounds of formula I,  - pharmaceutical compositions comprising a compound of formula I,  - novel phosphine oxides of the formula <CHEM> in which R5 and R6 are the same or different and each represents an unsubstituted or substituted phenyl group and R3 and R4 are as defined above, - a process for the preparation of phosphine oxides of formula XI.
Patent IE-38874-L (IE)
Title: N-organo-n-phosphonomethylglycine-n-oxide
IPC: C07F9/40
Filed: 1973-12-10
Abstract: This disclosure relates to N-organo-N-phosphonomethylglycine-N-oxides and derivatives thereof, to processes for producing same, and to herbicidal compositions and herbicidal methods. These compounds and the compositions containing them are useful as phytotoxicants or herbicides and as plant growth regulants.
Patent IE-802399-L (IE)
Title: Indolobenzoxazines
IPC: C07D498/06
Filed: 1980-11-19
Abstract: Novel Indolobenzoxazines of the formula 
<CHEM>
 and pharmaceutically acceptable salts thereof wherein
 (a) R is H, alkyl or aryl,
 R<1> is H, alkyl, aralkyl, cycloalkyl or alkenyl,
 R<2> is H, halogen or alkyl,
 R<3> is H, alkyl or aralkyl, and
 R<4> halogen, alkyl, hydroxy or alkoxy,
 and their preparation are disclosed. Those novel compounds having antihypertensive protactin inhibiting, and anti-Parkinson activity.
Patent IE-852472-L (IE)
Title: Autonomous yeast replication sequences
IPC: C12N15/81
Filed: 1985-10-08
Abstract: Novel autonomous replication sequences which are capable of maintaining plasmids as extrachromosomal elements in host strains of the genus Pichia are provided. In addition, novel constructs including these DNA sequences, as well as transformed organisms therewith are provided. Processes for producing the DNA sequences and constructs of the invention, as well as method for isolating such sequences from any source, are provided.
Patent IE-46108-L (IE)
Title: Cutting device
IPC: B26F3/02
Filed: 1977-12-15
Abstract: A cutting device for cutting sheets of material wherein a cutting member co-operates with a bed of upstanding pins which support the sheet. Although the cutting member may be a knife, it is preferably composed of a line of upstanding pins which are sufficiently long to penetrate through the material to be cut and to enter the bed of upstanding pins. The cutting device may comprise two drums mounted for rotation in opposite senses about parallel axes, one drum carrying the cutting member and the other the bed of pins, the tips of the pins being aligned with the cylindrical surface of their associated drum. (From US4184619 A) [FR2375012A1]
Patent IE-44672-L (IE)
Title: Production of cigarette filter units
IPC: A24D3/02
Filed: 1976-12-06
Abstract: Cigarette filter units are made in a long strip with alternate portions of fibrous and pourable filter material. The fibrous portions are first attached at spaced intervals to a sheathing strip which is wrapped practically right around them to form a cylinder with regular empty spaces between the fibrous portions and openings into the spaces. In a special unit, air is extracted from these spaces so that when the spaces enter a chamber containing pourable filter material, they suck the material in to fully fill the spaces. Excess filter material is brushed off the filter unit, and a sealing strip is stuck over the openings.
Patent IE-832917-L (IE)
Title: Electronic drainage systems
IPC: G05D16/20
Filed: 1983-12-12
Abstract: A system for electronically monitoring and controlling the drainage of fluids from a body cavity, including transducers for measuring suction, suction air flow, patient air flow, patient negativity and the like, and displays for rendering measured values in legible form. Various valves for regulating pressure and flow rates are electronically controlled according to desired values and direct measurements of the respective parameters.
Patent IE-893093-L (IE)
Title: Antiepileptic pyrazolopyridines
IPC: A61K31/44
Filed: 1989-09-27
Abstract: The disclosure pertains to certain pyrazolopyridin-carboxylates which are calcium channel blockers and possess anticonvulsant properties. By virtue of this activity, the compounds are useful in the treatment of epilepsy.
Patent IE-894057-L (IE)
Title: Use of ester oils in drilling fluids
IPC: E21B21/00
Filed: 1989-12-18
Abstract: Use of selected esters of monofunctional alcohols with 2 to 12, in particular 4 to 12, C atoms and aliphatically saturated monocarboxylic acids with 12 to 16 C atoms, which are fluid and pumpable in the temperature range of 0 to 5 DEG C, as the oil phase of invert drilling sludges, suitable for non-polluting exploitation of off-shore petroleum or natural gas deposits, and containing, in a closed oil phase, a disperse aqueous phase together with emulsifiers, loading agents, fluid-loss additives and, if necessary, other usual additives.
[EP0374672A1]