baber/WOPTO huggingface dataset:
Patent NZ-270300-A (NZ)
Title: Endoparasiticidal compositions containing praziquantel and epsiprantel together with certain cyclic depsipeptides
Inventor: MENCKE NORBERT
IPC: A61K38/08
Filed: 1995-01-06
Abstract: Endoparasitic activity of cyclic depsipeptides (I) comprising amino acid and hydroxycarboxylic acid units and having 6-30 ring atoms is increased by praziquantel (II) and epsiprantel (III). An endoparasitic agent contg. (I) together with (II) and (III) is also claimed. Known cpds. (I) are disclosed in EP382173 (depsipeptide PF 1022), WO9319053, J. Antibiotics 45 (1992) pp. 1207-1255 and pp 1273-1277, Helv. Chimn. Acta 46 (1963) pp 927-935 and pp 1715-1720, ibid, 47 (1964) pp. 166-173, Tetrahedron Letters 2 (1971) pp. 159-162, Biochem. Biophys. Res. Commun. 57 (1974) pp. 554-561 and Zh. Obshch. Khim. 41-(10) (10972) pp. 2320-2334. (II) is known from GB1441554 and (II) is known from EP134984 and EP185012.
Patent NZ-279309-A (NZ)
Title: Hemming paperboard method and apparatus to hem the edge of sheet material; a tongue, a recess inwardly of the tongue, a land inwardly of the recess and a groove being milled in the edge
Inventor: SAGVIK RAGNAR HARALD
IPC: B29C65/00
Filed: 1995-02-21
Abstract: PCT No. PCT/IB95/00113 Sec. 371 Date May 12, 1997 Sec. 102(e) Date May 12, 1997 PCT Filed Feb. 21, 1995 PCT Pub. No. WO95/23061 PCT Pub. Date Aug. 31, 1995A skiving method comprises forming by milling, along an edge zone of a packaging blank comprised of a liquid-absorbent layer and at least two liquid-barrier layers thereon, a tongue, a recess inwardly of the tongue, a land inwardly of the recess, and a groove inwardly of the land, folding over the edge zone to insert the tongue into the groove, and sealing the edge zone to the remainder of the sheet material, preferably by mechanical pressure alone.\!
Patent NZ-281715-A (NZ)
Title: Cooking food in inert-gas filled packages: food cooked by passing hot water around packages in pressure chamber
Inventor: ONO TAKUJI
IPC: A23L3/10
Filed: 1995-03-06
Abstract: An inert gas-filled cooking system is disclosed which provides for quick sterilization of food in inert gas-filled packages in a manner that prevents deterioration of food quality as well as assures a long taste guaranteed period by raising the temperature of a hot water to be applied onto the food packages in a sterilization tank so as to satisfy the retort sterilization requirements. The sterilization tank is pressurized at a predetermined value by control of an analog pressure regulating valve. The temperature of the hot water flowing from a heat exchanger into the sterilization tank is varied in a multi-staged fashion to follow a predetermined sterilization temperature-time curve by control of an analog steam regulating valve and a steam superheater. The hot water is applied onto the packaged food for sterilization. <IMAGE>
Patent NZ-302445-A (NZ)
Title: Housing portions, for gas valve or fluid control component, held together with a spring clip
Inventor: VAN DER ZEE JAN
IPC: F16K27/00
Filed: 1996-03-04
Abstract: A housing for a gas valve or the like, said housing comprising a first housing portion, which is connected to a second housing portion with the interposition of a flexible sealing element, whereby each housing portion is provided with a substantially circular contact surface, against which the sealing element abuts. The sealing element and/or either one or both contact surfaces are shaped in such a manner that only part of a contact surface is in contact with a part of the surface of the sealing element at the location of the contact surfaces. The two housing portions are kept a predetermined distance apart by connecting means, so that there will only be local deformation in the part of the sealing element that is located between the contact surfaces. The sealing element is provided with at least one annular rib, which abuts against a contact surface with part of its surface. The rib may taper off from the surface of the sealing element and be oriented towards the central axis of the ring, seen in cross-sectional view.
Patent NZ-331948-A (NZ)
Title: Determining presence and desnity of object using two radiation sources
Inventor: KULLENBERG RAGNAR
IPC: G01N33/46
Filed: 1996-03-21
Abstract: device for determining the size and density of an object includes at least one source 5 of electromagnetic radiation and at least one sensor 6 for measuring the intensity of the radiation.  The source 5 emits radiation of at least two wavelengths.  The size of the object is determined by measuring the distance between the source and the sensor, which abut the object.  The object is then irradiated, and the information from the sensor used to calculate the density of the object.  The radiation may be X-rays, with the wavelength varied by varying the voltage supplied to the X-ray source 5.
Patent NZ-332879-A (NZ)
Title: Use of fragments of leptin (ob protein) in medicaments for treating obesity or diabetes
Inventor: AL-BARAZANJI KAMAL A
IPC: A61K38/00
Filed: 1997-06-04
Abstract: The specification describes  the use of a leptin or ob peptide or a functional derivative, analogue or variant thereof, to modulate body weight substantially by means of modulating energy utilisation.  Pharmaceuticals containing the ob protein, or functional fragments of it, are formulated for treating obesity or diabetes.
Patent NZ-333198-A (NZ)
Title: Precipitated silicas contain an active substance for delayed release
Inventor: ESCH HEINZ
IPC: A61K8/25
Filed: 1998-12-07
Abstract: Oral hygiene compositions, particularly toothpastes, comprise precipitated silica which contains an active substance in delayed release form.  The active substance can contain fluoride ions.
Patent NZ-333214-A (NZ)
Title: IL-1/TNF-alpha-activated kinase (ITAK), and methods of making and using the same
Inventor: SIMS JOHN E
IPC: C12R1/91
Filed: 1997-06-09
Abstract: An isolated nucleic acid comprising a sequence selected from the group consisting of a) the sequence of nucleotides in SEQ ID NO:1, from nucleotide number 1 to nucleotide number 2940 or a sequence complementary to b) nucleic molecules capable of hybridization to a nucleic acid molecule of a) under conditions of moderate stringency and which encode a polypeptide that is capable of phosphorylating a b-casein substrate; and c) nucleic acid molecules which are degenerate as a result of the genetic code with respect to the nucleic acid molecules of a) or b). Also claimed is a recombinant expression vector, host cell containing the vector, isolated polypeptide comprising SEQ ID NO:2 and a method of screening for an agent that modulates the kinase activity of the polypeptide, and finally a kit for detecting kinase activity of the polypeptide.
Patent NZ-501270-A (NZ)
Title: Pharmaceutical composition comprising hyaluronan (Mr less than 750,00) and a disease modifier (cytokine, a peptide mimicking a cytokine or a protein mimicking a cytokine) to enhance delivery of disease modifiers
Inventor: TURLEY EVA ANNE
IPC: A61K47/66
Filed: 1998-05-11
Abstract: A pharmaceutical composition component comprising hyaluronan binding motif (HBM) peptide of the formula B(X7)B, in which B is either arginine (R) or lysine (K) and X7 contains no acidic residues and at least one basic amino acid interposed between a form of hyaluronan having a molecular weight (protein standard) less than 750,000 daltons and a disease modifier which comprises a peptide or protein. The HBM protects the therapeutic peptide or protein from protease attack or immune system recognition.
Patent NZ-502918-A (NZ)
Title: Selection and extraction of packets from MPEG stream in accordance with packet identity and assigned priority
Inventor: MERIC JEROME
IPC: H04N21/4147
Filed: 1998-07-23
Abstract: A device for use in a receiver/decoder for a broadcast digital television system in which received signals are passed through a receiver to the receiver/decoder and then to a television set. The receiver/decoder decodes a compressed MPEG-type signal, and is controlled by a remote controller handset, through an interface in the receiver/decoder. The receiver/decoder includes a plurality of interfaces to external units, and logical driver devices for the interfaces. The device produces a partial transport stream or an encapsulated data stream from the received broadcast digital data stream under the control of an application. This may allow a desired data stream, for example containing selected programmes to be recorded by a digital video recorder coupled to receive the output of the device or may facilitate communication with a computer.
Patent NZ-503729-A (NZ)
Title: Secreted mammary-specific breast cancer protein (mammaglobin) and vaccines
Inventor: WATSON MARK A
IPC: C12N15/09
Filed: 1998-09-18
Abstract: A purified and isolated DNA sequence and the encoded mammary-specific secreted protein, mammaglobin, are provided. Immunotherapy-based methods for treating a breast cancer patient with a mammaglobin-expressing tumour are also disclosed. Vaccines comprising mammaglobin antigens may be used for inducing a humoral and/or cell-mediated immune response against the tumour.
Patent NZ-505086-A (NZ)
Title: Dipeptide and tripeptide hemiasterlin analogs
Inventor: ANDERSEN RAYMOND
IPC: C07K5/065
Filed: 1998-12-18
Abstract: The compound of formula (I) is useful as an antimitotic agent.  In the compound of formula I: R1, R2, R3 and R4 are independently H, R or ArR-, or R1 and R2 and/or R3 and R4 are joined to form a 3-7 membered non-aromatic ring, the ring being within the definition of R; R5 is H, R, ArR- or Ar; R6, R7 and R8 are H, R or ArR-; R9 is Z-C(=O)-Y-; R is a saturated or unsaturated moiety having a linear, branched or non-aromatic cyclic skeleton containing one to ten carbon atoms, zero to four nitrogen atoms, zero to four oxygen atoms, and zero to four sulfur atoms, and the carbon atoms are optionally substituted with: =O, =S, -OH, OR10, O2CR10, -SH, -SR10, -SOCR10, -NH2, -NHR10, -N(R10)2, -NHCOR10, -NR10COR10, I, Br, Cl, F, CN, -CO2H, -CO2R10, -CHO, -COR10, -CONH2, -CONHR10, -CON(R10)2, -COSH, COSR10, -NO2, -SO3H, -SOR10, SO2R10, where R10 is a linear, branched or cyclic, one to ten carbon saturated or unsaturated alkyl group; X is -OH, -OR, =O, =S, -O2CR, -SH, -SR, -SOCR, -NH2, -NHR, -N(R)2, -NHCOR, -NRCOR, -I, -Br, -Cl, -F, -CN, -CO2H, -CO2R, -CHO, -COR, -CONH2, -CONHR, -CON(R)2, -COSH, -COSR, -NO2, -SO3H, -SOR, or -SO2R; Ar is an aromatic ring selected from phenyl, naphthyl, anthracyl, phenanthryl, furyl, pyrrolyl, thiophenyl, benzofuryl, benzothiophenyl, quinolinyl, isoquinolinyl, imidazolyl, thiazolyl, oxazolyl, and pyridinyl all optionally substituted with R or X; Y is a linear, saturated or unsaturated, one to six carbon alkyl group, optionally substituted with R, ArR-, or X; and, Z is -OH, -OR; -SH; -SR; -NH2; -NHR; -N(R)2; -NHCH(R11)COOH; and -NRCH(R11)COOH, where R11 is a moiety having the formula: R, or -(CH2)nNR12R13, where n=1-4 and R12 and R13 are independently H; R; or -C(NH) (NH2).  The compound of formula (I) is also described, but the following provisos apply: If R8 is H and Y is optionally substituted one carbon alkyl group, R1 and R2 are not joined to form imidazolidine, and If R8 is H, Y may only be substituted with RÆ or ArÆRÆ (where RÆ is a saturated linear, branched, or cyclic skeleton containing one to ten carbon atoms; and ArÆ is phenyl, naphthyl, anthracycl or phenanthryl, optionally substituted with RÆ).  Also described is a dipeptide intermediate of the formula (II), where R3-R7 are as defined for the compound of formula (I); Q and T are R1 or R2 as defined for the compound of formula (I) or Q and/or T is a protecting group, where at least one of Q and T is a protecting group.
Patent NZ-505436-A (NZ)
Title: Volatile dispenser with battery powered fan visible to indicate low battery voltage
Inventor: DAVIS BRIAN T
IPC: A61L9/12
Filed: 2000-06-27
Abstract: A battery powered dispenser for dispensing a volatile material from the cartridge 38 situated in the airflow created by the fan 20 between the inlet 14 and the outlet 16 of the dispenser housing, includes an electrical power cut-out that activates to cut off power to the fan motor 32 when the voltage of the battery 22 drops below a non-zero threshold level.  Because the fan is unrestrictedly visible to a user of the dispenser, the stopping of the rotation of the fan as the battery voltage gets low, implying a depletion of the volatile material, provides a prominent visual clue to the user of battery and volatile depletion.
Patent NZ-506820-A (NZ)
Title: Energy conversion apparatus using a free spherical rotor with recessed portions and a permanent magnet
Inventor: FIELDING FRANK JOHN
IPC: H02K15/02
Filed: 2000-12-08
Abstract: A rotor includes at least one substantially recessed portion and at least one spherical portion. The spherical portion forms a first half of the rotor and the recessed portion forms a second half of the rotor. The weight of the spherical portion and the weight of the substantially recessed portion are adapted to place the centre of mass of the rotor at an equal distance to all points on the surface of the spherical portion of the rotor. The rotor may further include at least one magnet. An energy conversion apparatus includes at least one rotor. The rotor is adapted to rotate with a substantially circular motion within a housing.
Patent NZ-507391-A (NZ)
Title: The compound ((3-(2-amino-1,2-dioxoethyl)-2-methyl-1- (phenylmethyl)-1H-indol-4-yl)oxy)acetic acid N-morpholino ethyl ester and its use as a sPLA 2 inhibitor
Inventor: DENNEY MICHAEL LYLE
IPC: A61K31/5377
Filed: 1999-04-20
Abstract: Described is the compound ((3-(2-amino-1,2-dioxoethyl)- 2-methyl-1-(phenylmethyl)-1H-indol-4-yl)oxy)acetic acid N- morpholino ethyl ester. Also described is a pharmaceutical composition comprising the above-described compound. The above-described compound is useful for treating conditions induced or maintained by overproduction of sPLA2 in patients in need thereof.
Patent NZ-508477-A (NZ)
Title: Antihistaminic piperidine derivatives and intermediates
Inventor: AYERS TIMOTHY ALLEN
IPC: C07C259/06
Filed: 1999-06-17
Abstract: Antihistaminic piperidine derivatives of formula shown herein and a process for the preparation thereof is disclosed, wherein R1 is H or C1-C6alkyl wherein the C1- C6alkyl moiety is straight or branched; R2 is -COOH or - COOalkyl wherein the alkyl moiety has from 1 to 6 carbon atoms and is straight or branched; or stereoisomers or pharmaceutically acceptable acid addition salt thereof.
Patent NZ-508785-A (NZ)
Title: Stable gene formulations
Inventor: NAGAHARA SHUNJI
IPC: A61K48/00
Filed: 1999-05-19
Abstract: A process for preparing a formulation for gene therapy, whereby a saccharide and/or a non-hydrophobic amino acid and/or an organic acid are added to a preparation comprising a desired gene or a vector incorporated with a desired gene, the resultant preparation is lyophilized to give a stable gene formulation, wherein degradation of the gene or vector is prevented.
Patent NZ-512292-A (NZ)
Title: Sulfonamide hydroxamates that inhibit procollagen C- proteinase
Inventor: BILLEDEAU ROLAND JOSEPH
IPC: A61P21/00
Filed: 1999-12-14
Abstract: Compounds of formula (Ia) are disclosed, for which the substituents are defined herein. The compounds are used in the manufacture of medicaments for the inhibition of procollagen C-proteinase.
Patent NZ-518049-A (NZ)
Title: A construction for automatically milking animals
Inventor: FRANSEN RENATUS IGNATIUS JOSEP
IPC: A01J5/017
Filed: 2002-03-27
Abstract: A construction for automatically milking animals is provided with a milking robot and a computer which is capable of being connected with one or more measuring instruments which are related to a number of functions of the construction. A monitoring programme for the functions is installed in the computer, with the aid of which the computer is suitable for determining, on the basis of a comparison of data from one or more of the measuring instruments with reference data related to the functions, a diagnosis in relation to an anticipated fault in one or more of the functions. The early determination of a diagnosis enables to warn a user and/or a service mechanic, who is then able to take in time the possibly required measures to avoid the anticipated malfunction.
Patent NZ-518079-A (NZ)
Title: Method in connection with the production of mechanical pulp
Inventor: MOBERG ANDERS
IPC: D21B1/32
Filed: 2000-09-06
Abstract: A method in connection with the production of mechanical pulp from a cellulose containing material, wherein the material is processed in at least one refining step to produce pulp. According to the invention, the pulp is fractionated (4), after a first refining step (1), in order to separate primary fines (5) from the pulp. The invention also relates to a mechanical pulp, produced by the method, and to a paperboard, which at least partly consists of such mechanical pulp.
Patent NZ-518663-A (NZ)
Title: Heterocyclic dihydropyrimidines as potassium channel inhibitors
Inventor: ATWAL KARNAIL S
IPC: A61P11/00
Filed: 2000-12-04
Abstract: A compound of formula I* where it is used to treat atrial arrhythmias such as atrial flutter, control heart rate, gastrointestinal disorders such as reflux oesophagitis and motility disorders, diabetes, chronic obstructive pulmonary disorder (COPD), migraine, epilepsy and conditions associated with Ikur-.
Patent NZ-520468-A (NZ)
Title: Aminomethyl-phenyl-cyclohexanone derivatives
Inventor: PUETZ CLAUDIA
IPC: A61P23/00
Filed: 2000-12-27
Abstract: Aminomethyl-phenyl-cyclohexanone derivatives of formula I or Ia, their diastereomers, enantiomers and salts formed with a physiologically tolerated acid. Also disclosed are processes for preparing the same, pharmaceutical compositions comprising the same, and methods of using the same for the treatment of pain, inflammatory reaction, allergic reactions, depression, drug abuse, alcohol abuse, gastritis, cardiovascular disease, respiratory tract disease, coughing, mental illness, epilepsy, urinary incontinence, itching, and diarrhoea.
Patent NZ-528501-A (NZ)
Title: Aromatase inhibition to enhance assisted reproduction
Inventor: CASPER ROBERT F
IPC: A61K31/56
Filed: 2002-04-17
Abstract: The use of at least one aromatase inhibitor in the production of a medicament for improving the implantation and pregnancy rates for a female undergoing assisted reproduction treatment, which comprises one or more daily doses of an aromatase inhibitor (AI) for administration during assisted reproduction cycles or ovarian stimulation cycles, wherein the doses of AI are selected from amounts effective to reduce serum estradiol levels. Also disclosed are related pharmaceutical preparations and packages.
Patent NZ-529345-A (NZ)
Title: The use of a melagatran and inogatran and their derivatives for the manufacture of a medicament for the treatment of idiopathic pulmonary fibrosis (IPF) and pulmonary fibrosis
Inventor: KIRK IAN
IPC: A61K38/05
Filed: 2002-05-16
Abstract: Use of a gatran, such as inogatran or melagatran, or a pharmaceutically-acceptable derivative thereof, for the manufacture of a medicament for the treatment of pulmonary fibrosis is disclosed.
Patent NZ-531520-A (NZ)
Title: Tricyclic imidazopyridines
Inventor: ZIMMERMAN PETER JAN
IPC: C07D491/147
Filed: 2002-07-31
Abstract: Tricyclic imidazopyridine compounds of the formula (I) are disclosed, wherein the substituents and symbols are as defined in the specification. These compounds inhibit the secretion of gastric acid and thus are useful for the prevention and treatment of gastrointestinal disorders.
Patent NZ-531905-A (NZ)
Title: Fastening system and components therefor
Inventor: FERNANDO SAMAN
Filed: 2004-03-23
Abstract: A fastener assembly for fastening the foot of a top hat section batten 46 to a structural member 44 and a method of fastening the assembly are disclosed. The assembly includes a self drilling screw 42 and an oblong shaped washer 60 captively held on the shank of the screw. The washer is elongated and substantially flat with a stiffening portion extending across the width of the washer on each side of the washer's hole.
Patent NZ-536519-A (NZ)
Title: Modified hydroxypropyl methyl cellulose polymeric films
Inventor: AYERS VICTORIA JANE
IPC: C08J5/18
Filed: 2003-05-12
Abstract: A hydroxypropyl methyl cellulose film is disclosed, which comprises hydroxypropyl methyl celiulose plasticised with a plasticiser comprising a carboxylic acid such as maleic acid, fumaric acid or adipic acid and/or one or more of benzyl alcohol; ethanol; propanol; isopropanol; butanol; structural isomers of butanol; pentanol; structural isomers of pentanol; hexanol; structural isomers of hexanol; and/or a salt of any of the preceding acids or alcohols. The film is safe for human consumption and finds use as a wall material of an ingestible delivery capsule, e.g. containing a dose of a pharmaceutical preparation.
Patent NZ-537803-A (NZ)
Title: Improved method of making nevirapine
Inventor: BOSWELL ROBERT F
IPC: C07D471/10
Filed: 2003-06-02
Abstract: Disclosed is a process for preparing nevirapine, comprising the steps of: (a) reacting a 2-halo-3-pyridinecarbonitrile of formula (I) with cyclopropylamine, to yield 2-(cyclopropylamino)-3-pyridinecarbonitrile, (b) hydrolysing the 2-(cyclopropylamino)-3-pyridinenitrile to yield 2-(cyclopropylamino)-3-pyridine carboxylic acid, (c) isolating the 2-(cyclopropylamino)-3-pyridine carboxylic acid from the reaction medium, (d) treating the 2-(cyclopropylamino)-3-pyridine carboxylic acid with a chlorinating agent to yield 2-(cyclopropylmino)-3-pyridinecarbonyl chloride, (e) reacting the 2-(cyclopropylamino)-3-pyridine carbonyl chloride with a 2-halo-4-methyl-3-pyridinamine of formula (II), and (f) cyclising the N-(2-halo-4-methyl-3-pyridinyl)-2-(cyclopropylamino)-3-pyridinecarboxamide by treatment with a strong base, to yield nevirapine.
Patent NZ-542754-A (NZ)
Title: Glazing compositions
Inventor: PURDY KEVIN GRANT
Filed: 2003-10-07
Abstract: Disclosed is a glazing composition or a composition having characteristics or a characteristic of a glazing composition, said composition comprising or including: at least one particulate material; a polymeric material capable of polymerising (at least over time when, for example, exposed to the ambient air) or a resin; an oil and/or glyceride; a drier; a thixotroping agent; and a biocide; wherein the composition has one or more of the following characteristics: (i) is toolable; (ii) is, or becomes upon manipulation and/or application to a suitable substrate to be encountered when used as a glazing composition, tacky and self-priming; (iii) skin forms rapidly; (iv) by polymerisation skin forms rapidly; (v) minimal oil migration to surface of composition upon application to the substrate; (vi) by polymerisation hardens from a toolable state to allow painting, and/or (vii) hardens from a toolable state to allow painting.
Patent NZ-548358-A (NZ)
Title: Method of identifying agonists of insulin-like growth factor-1
Inventor: SCHAFFER MICHELLE
IPC: C07K14/65
Filed: 2002-02-01
Abstract: Disclosed is a method of identifying indirect agonists of IGF-1, comprising co-crystallizing a candidate indirect agonist of IGF-1 with IGF-1 to form a co-crystalline structure and determining if the candidate agonist binds to one or both of two patches on IGF-1, wherein one patch has the amino acid residues GIu 3, Thr 4,Leu 5, Asp 12, Ala 13, Phe 16, Val 17, Cys 47, Ser 51, Cys 52, Asp 53, Leu 54 and Leu 57, and the second patch has the amino acid residues Val 11, GIn 15, Phe 23, Phe 25, Asn 26, Val 44, Phe 49, and Arg 55, and wherein binding occurs if there is at least one contact between each listed amino acid residue of a given patch and the candidate agonist that is less than or equal to 6 angstroms in the co-crystalline structure. Also disclosed is a co-crystalline complex of IGF-1 and N, N-bis(3-D-gluconamidopropyl)-deoxycholamine. (62) Divided Out of 526672