baber/WOPTO huggingface dataset:
Patent WO-2020237078-A1 (WO)
Title: Drug conjugates and methods of using same
Inventor: COCHRAN JENNIFER
IPC: C07K16/22
Filed: 2020-05-21
Abstract: Provided are conjugates. In certain aspects, provided are drug conjugates that include a knottin peptide comprising an engineered loop that binds to a cell surface molecule, and an anti-microtubule agent conjugated to the knottin peptide via a linker. In some aspects, provided are drug conjugates that include a fusion protein that includes a knottin peptide comprising an engineered loop that binds to a cell surface molecule, fused to an antibody subunit or fragment thereof. Such drug conjugates further include a drug conjugated to the fusion protein. Also provided are compositions and kits that include the conjugates of the present disclosure. Methods of using the conjugates, e.g., for therapeutic purposes, are also provided.
Patent WO-2020243513-A1 (WO)
Inventor: DAVIS BRADLEY
IPC: A63B23/12
Filed: 2020-05-29
Abstract: Provided herein are embodiments of a barbell spotting apparatus having all the benefits of a free-floating, unconstrained barbell in both the horizontal and vertical axes with the safety of a dedicated spotting mechanism, while addressing safety, noise, and space concerns raised by typical barbell apparatus. The embodiments herein permit a loaded barbell to be positioned in line with the axis of motion of the lift to be performed at both the beginning and end of the lift.
Patent WO-2020256944-A1 (WO)
Title: Lentille à ouverture interne
Inventor: JENKINS KURT
IPC: G02B1/04
Filed: 2020-06-03
Abstract: L'invention concerne une lentille à ouverture interne qui comprend une première région composée d'un matériau à capacité de transmission optique, une seconde région composée d'un matériau à capacité de transmission optique, et un élément formant ouverture interne. La première région composée d'un matériau à capacité de transmission optique définit une première surface de la lentille et la seconde région définit une seconde surface de la lentille qui est opposée à la première surface. L'élément formant ouverture interne est disposé d'un seul tenant entre la première région et la seconde région et définit l'ouverture de la lentille.
Patent WO-2021251965-A1 (WO)
Title: Automated injection device for administering antigens to animals
Inventor: ZHOU JUN
IPC: A61M5/32
Filed: 2020-06-11
Abstract: An syringe injection device for performing automated injections of antigen emulsions into animals to provoke an immune response. The injection device comprises an upper module and a lower module that are locked together. On the upper module, there is a syringe groove for receiving a syringe. The syringe injection device works by electric motor actuation, which spins a screw drive. The internal mechanism causes a push block to urge against the injection plunger of the syringe. This expels the antigen emulsion out of the syringe for injection into the animal.
Patent WO-2021003016-A1 (WO)
Inventor: WYATT KARYN
IPC: A41D27/10
Filed: 2020-06-16
Abstract: La présente invention concerne un vêtement comprenant une paire de manches de bras et une pièce de raccord interchangeable ou intégrée. La paire de manches de bras comprend une première manche de bras et une seconde manche de bras conçues pour recouvrir les bras d'un utilisateur. La pièce de raccord est configurée pour relier la première manche de bras au niveau d'une extrémité supérieure de celle-ci et la seconde manche de bras à une extrémité supérieure de celle-ci. La pièce de raccord est portée à l'arrière de l'utilisateur entre les régions d'épaules.
Patent WO-2021066913-A1 (WO)
Inventor: KLEIN CHRISTIAN
IPC: G06F9/445
Filed: 2020-06-30
Abstract: Technologies are disclosed herein for positioning application windows based on existing application layout and anticipated user workflows. When an existing application window and a recently launched application window are determined to be related to a workflow, and the default position of the recently launched application window is determined to overlap with the existing application window, the recently launched application window may be displayed in a non-default display region to avoid occlusion. By avoiding occlusion, the foldable device may provide a user-friendly application layout, reducing the number of times a user will move, resize, or switch between application windows in the workflow. This in turn may improve device performance and efficiency while reducing errors attributable to user input. The user-friendly layout may also enable a user to view more content at the same time, increasing productivity, reducing eye strain, facilitating operations such as cut and paste, etc.
Patent WO-2021066921-A1 (WO)
Inventor: SWEITZER ZACHARY
IPC: A61F2/46
Filed: 2020-07-15
Abstract: A surgical hammer (100) that includes a handle (102), a shaft (104) extending from the handle and a hammer head (106) connected to the shaft. The hammer head includes a slot (108) extending through the hammer head and in fluid communication with a distal end of the hammer head, a first internal cavity (612) within the hammer head spaced laterally from the slot, and a second internal cavity (614) within the hammer head spaced laterally from the slot.
Patent WO-2021026448-A1 (WO)
Inventor: MAY JASON
IPC: A61B17/60
Filed: 2020-08-07
Abstract: A technique for correcting a bone deformity, such as a bunion, may be performed using an instrument that defines a spacer body connected to a fulcrum. The spacer body portion of the instrument can be inserted into a joint space between opposed bone ends. The fulcrum body can be inserted between adjacent metatarsals. An angle set between the spacer body and fulcrum body can help properly position both features within different joint spaces for ensuring that subsequent steps of the surgical procedure are properly performed and instrumentation is appropriately aligned.
Patent WO-2021050216-A1 (WO)
Title: Beam-specific group delay per frequency lookup table signaling for high-precision multi-round-trip-time
Inventor: MANOLAKOS ALEXANDROS
IPC: H04B7/06
Filed: 2020-08-18
Abstract: Disclosed are techniques for reporting a group delay-per-frequency lookup table for transmit and receive beams. In an aspect, a user equipment (UE) receives, from a transmission-reception point (TRP), a first downlink reference signal on at least one downlink reference signal resource using a downlink receive beam, transmits, to the TRP, an uplink reference signal on at least one uplink reference signal resource using an uplink transmit beam, determines a parameter representing a difference between a reception time of the first downlink reference signal and a transmission time of the uplink reference signal, transmit the parameter to a network entity, and transmits, to the network entity, a first lookup table or an identifier of the first lookup table, wherein the first lookup table represents per-frequency group delay information for the downlink receive beam and/or the uplink transmit beam.
Patent WO-2021041988-A1 (WO)
Title: Outil en contact avec le sol et système de surveillance et procédés destinés à un équipement de terrassement
Inventor: CARPENTER CHRISTOPHER M
IPC: E02F9/28
Filed: 2020-08-28
Abstract: L'invention concerne un système et un outil de surveillance d'un équipement de terrassement observant des choses comme l'identification de pièce, les fissures, la déformation, le présence, les limites opérationnelles, les défaillances d'équipement, les violations de proximité d'équipement, les capteurs de système de localisation, l'état, l'utilisation et/ou la performance des produits sur un équipement de terrassement utilisé, par exemple, dans des environnements d'exploitation minière, de construction et/ou de dragage.
Patent WO-2021080702-A1 (WO)
Title: Spring-loaded fastening system for process chamber liners
Inventor: WEBB BENJAMIN
IPC: F16B2/06
Filed: 2020-09-10
Abstract: A spring-loaded fastening system for fastening a liner to a structure, including a spring- loaded fastener with a cleat defining an interior cavity, a spring element disposed on a floor of the interior cavity, and a shoulder bolt with head portion disposed on the spring element, with a shoulder portion of the shoulder bolt extending through a mounting aperture in a floor of the interior cavity and a threaded portion of the shoulder bolt fastened to the structure. The system further includes a hanger pocket in a rear surface of the liner including a first portion with an opening large enough to accommodate a diameter of a lower portion of the cleat and not large enough to accommodate a diameter of an upper portion of the cleat, and a second portion adjoining the first portion with an opening large enough to accommodate the diameter of the upper portion of the cleat.
Patent WO-2021055649-A1 (WO)
Title: Dual live valve shock having main damper and base valve actively controlled
Inventor: WOELFEL REGAN
IPC: F16F9/512
Filed: 2020-09-17
Abstract: A vehicle damper assembly is disclosed. The damper includes a reservoir, a cylinder having an inner diameter (ID) and fluidly coupled with the reservoir and a rod and a piston. The piston coupled to the rod and configured to divide the cylinder into a compression side and a rebound side. The damper further includes an active base valve to provide independent flow control for a reservoir flow path between the cylinder and the reservoir. The damper also includes an active main valve to provide independent flow control for a piston flow path fluidly coupling the compression side with the rebound side.
Patent WO-2021055847-A1 (WO)
Title: Computer-based systems, computing components and computing objects configured to implement dynamic outlier bias reduction in machine learning models
Inventor: RICHARD B JONES
IPC: G06F17/18
Filed: 2020-09-18
Abstract: Systems and methods include processors for receiving training data for a user activity; receiving bias criteria; determining a set of model parameters for a machine learning model including: (1) applying the machine learning model to the training data; (2) generating model prediction errors; (3) generating a data selection vector to identify non-outlier target variables based on the model prediction errors; (4) utilizing the data selection vector to generate a non-outlier data set; (5) determining updated model parameters based on the non-outlier data set; and (6) repeating steps (1)-(5) until a censoring performance termination criterion is satisfied; training classifier model parameters for an outlier classifier machine learning model; applying the outlier classifier machine learning model to activity-related data to determine non-outlier activity-related data; and applying the machine learning model to the non-outlier activity-related data to predict future activity-related attributes for the user activity.
Patent WO-2021061638-A1 (WO)
Title: Methods related to a structure of high-affinity human pd-1/pd-l2 complex
Inventor: TANG SHAOGENG
IPC: G16C20/64
Filed: 2020-09-22
Abstract: Variants of human PD-1 comprising one or more of amino acid substitutions in residues corresponding to N74, T76 and A132 of SEQ ID NO:1 are described. Also described are structures, obtained using X-ray crystallography, of the human PD-1/PD-L2 complex and mutant PD-1 variants. The structures of human PD-1 described in the present disclosure are useful in drug discovery, including small-molecule drug discovery. Accordingly, methods of using the structures in drug discovery are also described.
Patent WO-2021061706-A1 (WO)
Inventor: TAYLOR ALEXANDER
IPC: C07D491/20
Filed: 2020-09-23
Abstract: The disclosure is in part directed to crystalline forms of (R)- 1'-(3 -(3,4-dihydro- 1,5- naphthyridin-1(2H)-yl)-1H-pyrazolo[3,4-b]pyrazin-6-yl)-3H-spiro[benzofuran-2,4'- piperidin]-3 -amine, its salt, and variants thereof.
Patent WO-2021062354-A1 (WO)
Title: Systèmes de communication multi-faisceau multi-couche
Inventor: RAKIB SHLOMO SELIM
IPC: H04B7/0404
Filed: 2020-09-28
Abstract: Un dispositif de communication sans fil comprend un port d'alimentation comprenant de multiples alimentations d'entrée, un sous-système de précodage qui est électriquement connecté au port d'alimentation; et un sous-système d'antenne connecté électriquement au sous-système de précodage. Le sous-système d'antenne est configuré pour transmettre un signal de sortie du sous-système de précodage à de multiples stations sans fil au moyen de multiples faisceaux. Le sous-système de précodage est configuré pour effectuer une opération de précodage sur un signal d'entrée provenant du port d'alimentation, l'opération de précodage maximisant un niveau de signal souhaité pour le rapport d'interférence des transmissions vers les multiples stations sans fil.
Patent WO-2021071728-A1 (WO)
Title: Dosing regimen for injectable cetirizine
Inventor: DU JIE
IPC: A61P37/08
Filed: 2020-10-01
Abstract: Described herein is a method of administering injectable cetirizine or levocetirizine including intravenously injecting a mammal in need thereof with a therapeutically effective amount of an injectable cetirizine or levocetirizine composition, wherein the mammal receives a maximum daily dose of the cetirizine or levocetirizine that is no more than 15 times a maximum recommended daily clinical dose for the mammal.
Patent WO-2021092010-A1 (WO)
Title: Adaptive joint and non-joint qcl indication via ue report
Inventor: PEZESHKI HAMED
IPC: H04B7/08
Filed: 2020-11-04
Abstract: In one aspect, a method of wireless communication includes receiving, by a user equipment (UE), data from one or more beam pairs of a plurality of beams at least partially concurrently; determining, by the UE, one or more signal parameters for the one or more beam pairs; determining, by the UE, one or more joint quasi co-located (QCL) indicators for the one or more beam pairs and one or more non-joint QCL indicators for the one or more beam pairs; and transmitting, by the UE, a measurement report including the one or more joint QCL indicators and the one or more non-joint QCL indicators. In another aspect, a method of wireless communication includes determining a particular beam or beams for transmitting second data based on the measurement report; and transmitting the second data using the particular beam or beams. Other aspects and features are also claimed and described.
Patent WO-2021096864-A1 (WO)
Title: System and method for generating, and delivering to standing users, therapeutic acoustic vibrations
Inventor: CADWELL CARLTON M
IPC: A61H1/00
Filed: 2020-11-10
Abstract: A system of delivering multi -frequency acoustic vibrations into the body of a user for increasing a voltage of the cells of the user's body is provided. The system including: a base assembly including a space defined by a top plate and a bottom plate including voice coils, magnets and springs, wherein each voice coil is aligned with a magnet and the springs maintain a predefined thrust between the top and bottom plate, each voice coil lying within a magnetic flux of a magnet for producing acoustic waves of predefined frequencies for deliverance into the user's body through the user's feet when the user is standing on the base assembly; and a tower assembly tethered with the base assembly, and including at least one speaker, and one or more cell exciter pads for attaching with a portion of the user's body, the speaker and pads producing acoustic waves of predefined frequencies for deliverance into the user's body.
Patent WO-2021133533-A1 (WO)
Title: Systèmes de détection par fluorescence en temps réel destiné à des dispositifs médicaux
Inventor: SIPPLE DANIEL
IPC: A61M25/01
Filed: 2020-12-04
Abstract: L'invention concerne une sonde permettant la détection en temps réel d'un biomarqueur cible comprenant une aiguille, une sonde luminescente à l'intérieur de l'ouverture de l'aiguille, un revêtement comprenant un matériau luminescent biomarqueur en contact avec un tissu biologique, et un revêtement consommateur d'ions à l'intérieur de l'aiguille et adjacent au revêtement. La sonde selon l'invention permet l'analyse en temps réel de sang pendant des procédures médicales. De plus, l'invention concerne un système de détection de biomarqueur comprenant un matériau luminescent biomarqueur à la pointe ou à l'intérieur de la pointe d'une aiguille et un coupleur optique.
Patent WO-2021141819-A1 (WO)
Title: Adjustable balancing block for closed loop die control
Inventor: THADDAEUS SUNIL
IPC: B21J13/08
Filed: 2020-12-31
Abstract: A stamp tool assembly is provided that includes a forming cavity for shaping a blank into a formed part. The stamp tool assembly includes adjustable block assembly for modifying the amount of material draw-in from subsequently stamped blanks. A draw-in sensor measures the amount of material from the blanks that is not drawn-into the forming cavity during each stroke. Based on the readings from the draw-in sensor, the adjustable block assembly is expanded or reduced. The adjustable block assembly includes a pair of opposing inclined plates having interlocking teeth such that movement of one plate with respect to the other plate changes a vertical extension of the adjustable block assembly. The adjustable block assembly sets the spacing between two opposing draw-in surfaces, which, in turn, changes the amount of draw-in. Multiple adjustable block assemblies and draw-in sensors may be used in conjunction and controlled via a controlling system.
Patent WO-2021163597-A1 (WO)
Title: Multi-process analyte monitoring and communication system
Inventor: AHMADI FARHANEH
IPC: G16H50/20
Filed: 2021-02-12
Abstract: Systems and methods are provided for improved analyte processing with data that was captured by analyte monitors. Analyte data entries are processed with multiple child processes and the child processes pass results to a parent process. The parent process aggregates the children results to result in faster processing times. The analyte data is processed in a backend system that is linked to user computing devices with graphical user interfaces.
Patent WO-2021194668-A1 (WO)
Inventor: KELLY DOUGLAS JAMES
IPC: G11B7/0065
Filed: 2021-02-22
Abstract: A holographic data storage system comprises an emitter system, a holographic recording medium, and an input waveguide network formed of one or more multimode optical waveguides. The holographic recording medium has multiple recording regions, each optically coupled to a corresponding one of multiple out-coupling regions of the input waveguide network, the holographic data storage system arranged to persistently write data of an input beam, received at any one of the out-coupling regions, to the corresponding recording region. A controller is coupled to at least one of the emitter system and at least one controllable guiding element of the input waveguide network and controls at least one optical characteristic of the input beam or the at least one guiding element, so as to guide the input beam from an in-coupling region to any selected one of the multiple out-coupling regions. Similar waveguide networks are provided for carrying reference and output beams.
Patent WO-2021173580-A1 (WO)
Inventor: HARRIS JEFFREY
IPC: G06F16/583
Filed: 2021-02-23
Abstract: In a method for identification of an Internet meme, a plurality of sources is monitored for digital visual content comprising a visual moment and a caption. It is determined whether instances of digital visual content include a same visual moment. Provided the instances of digital visual content include the same visual moment, the instances of digital visual content including the same visual moment are identified as similar digital visual content. Each instance of the similar digital visual content is tracked. Provided a total number of instances of the similar digital visual content exceeds an Internet meme threshold, the similar digital visual content is identified as an Internet meme, wherein the same visual moment is a root visual moment and each caption corresponds to a different iteration of the Internet meme.
Patent WO-2021230954-A1 (WO)
Title: A wellbore servicing fluid and methods of making and using same
Inventor: JADHAV RAHUL
IPC: E21B43/26
Filed: 2021-03-02
Abstract: A method comprising (a) contacting a suspension composition, water, and optionally one or more additives to form a wellbore servicing fluid at a location proximate a wellsite; wherein the suspension composition comprises a particulate material, an organic carrier fluid, and a suspension viscosifier; and (b) placing the wellbore servicing fluid in a wellbore penetrating a subterranean formation. The wellsite comprises an offshore platform, a floating vessel, or combinations thereof; and wherein the wellbore is offshore. A suspension composition comprising a particulate material, an organic carrier fluid, and a suspension viscosifier; wherein the particulate material is substantially insoluble in the organic carrier fluid; wherein the particulate material comprises a water-interactive material and/or a water-insoluble material; and wherein the organic carrier fluid comprises a glycol and/or a glycol ether.
Patent WO-2021211654-A1 (WO)
Title: Recovery boiler startup burner assembly
Inventor: IMIG GREGORY ALAN
IPC: D21C11/12
Filed: 2021-04-14
Abstract: A startup burner assembly for a recovery boiler, the startup burner assembly includes a housing having a burner end and a second end distal to the burner end; a main fuel conduit disposed within the housing; and high-pressure air conduits disposed within the burner end of the housing. The high-pressure air conduits include angled air injection nozzles configured to direct high-pressure air exiting the burner end of the startup burner assembly in a rotational direction.
Patent WO-2021236993-A1 (WO)
Inventor: ABDUEVA DIANA
IPC: G16B30/10
Filed: 2021-05-20
Abstract: La présente invention concerne des méthodes et des systèmes destinés à diverses utilisations d'acides nucléiques acellulaires (ANcf). Un typage fonctionnel de motifs de fragmentation d'ANcf peut être utilisé pour la détection, le diagnostic et la surveillance non invasifs d'une maladie. Un mode de réalisation permet de déterminer un stade de cancer chez un sujet, la progression d'un cancer chez un sujet, ou la réactivité au traitement d'un cancer chez un sujet. Un autre mode de réalisation de l'invention peut faire appel à des méthodes de diagnostic sans séquençage.
Patent WO-2021237061-A1 (WO)
Title: Methods and compositions for treating a fibrotic disease
Inventor: GRINSTAFF MARK
IPC: A61K47/34
Filed: 2021-05-21
Abstract: The present invention provides compositions and methods for the treatment of diseases and disorders. In some embodiments the compositions and methods involve administration of a microparticle, or composition thereof that includes an antifibrotic.
Patent WO-2022173462-A1 (WO)
Title: Désagrégation de trajet de commande et trajet de données
Inventor: WANG QINGBO
IPC: G06F3/06
Filed: 2021-06-25
Abstract: Un dispositif de réseau comprend au moins un port de chemin de commande et des ports de chemin de données configurés pour communiquer sur un réseau. Une demande de connexion est reçue d'un hôte via un port de voie de commande, et une ressource du dispositif de réseau est attribuée à l'hôte. Un port de trajet de données est déterminé parmi la pluralité de ports de trajet de données pour une communication entre l'hôte et la ressource attribuée. Une indication du port de trajet de données déterminé est envoyée à l'hôte par l'intermédiaire du port de trajet de commande pour une communication sur un trajet de données entre l'hôte et la ressource attribuée. Selon un aspect, une interface réseau comprend au moins un port de trajet de commande et une première pluralité de ports de trajet de données configurés pour communiquer sur un réseau. Une demande de connexion est reçue en provenance d'un hôte par l'intermédiaire d'un port de trajet de commande, et un dispositif connecté localement est attribué à l'hôte.