Patent SG-11201809161U-A (SG)
Title: Anti-microbial compositions comprising quaternary organosilane compounds
Inventor: KEMP ANDREW
IPC: A01N55/00
Filed: 2017-04-24
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 09 November 2017 (09.11.2017) WIP0 I PCT IillIIIIIIII011101110VIII110um o om 11°111E1 VIII oimIE (10) International Publication Number WO 2017/190972 Al (51) International Patent Classification: MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, A01N 33/12 (2006.01) A01N 55/00 (2006.01) TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, (21) International Application Number: KM, ML, MR, NE, SN, TD, TG). PCT/EP2017/059676 Published: (22) International Filing Date: with international search report (Art. 21(3)) 24 April 2017 (24.04.2017) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 1607699.4 03 May 2016 (03.05.2016) GB (71) Applicant: Q SURGICAL LTD [GB/GB]; Unit la, Sum- merlands Trading Estate, Endmoor, Kendal Cumbria LA8 OFB (GB). (72) Inventors: KEMP, Andrew; Unit la, Summerlands Trad- ing Estate, Endmoor, Kendal Cumbria LA8 OFB (GB). PIL- LANS, Charles Melville; Unit la, Summerlands Trading Estate, Endmoor, Kendal Cumbria LA8 OFB (GB). (74) Agent: PROBERT, Gareth David; Potter Clarkson LLP, The Belgrave Centre, Talbot Street, Nottingham NG1 5GG (GB). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, (54) Title: ANTI-MICROBIAL COMPOSITIONS COMPRISING QUATERNARY ORGANOSILANE COMPOUNDS (57) : An antimicrobial composition comprising at least two quaternary ammonium compounds selected from: (i) a quaternary 1-1 ammonium compound having the formula: A4_„Si(R- Ntl a R l bZ)n and (ii) a quaternary ammonium compound having the formula: NHcR l dZ wherein in each of the at least two quaternary ammonium compounds A, R, R, a, Z and n are independently selected, and: 1 . A is a member selected from the group consisting of alkoxy radicals, alkylether alkoxy radicals, and alkyl radicals; R is a divalent C:N hydrocarbon radical; each R 1 is independently a member selected from the group consisting of benzyl, alkyl radicals, alkyl ether hydrocarbon radicals, hydroxyl-containing alkyl radicals, and nitrogen-containing hydrocarbon radicals; Z is a member selected from 1 -1 the group consisting of chloride, bromide, iodide, tosylate, hydroxide, sulfate and phosphate; a is 0, 1 or 2, b is 1, 2 or 3, and the sum IN of a and b is 3; c is 0, 1, 2 or 3, d is 1, 2, 3 or 4, and the sum of c and d is 4; and n is 1, 2 or 3; and wherein the composition comprises at least two quaternary ammonium compounds of formula (i). A method of making an anti-microbial composition, and a method of \" reducing the number of micro-organisms on a surface, are disclosed.