baber/WOPTO huggingface dataset:
Patent NZ-572199-A (NZ)
Title: Therapeutic intervention in a genetic disease in an individual by modifying expression of an aberrantly or abnormally expressed gene
Inventor: T HOEN PETER ABRAHAM CHRISTIAAN
IPC: A61K38/18
Filed: 2007-04-20
Abstract: Disclosed is the use of a BMP-4 anti-sense oligonucleotide in the manufacture of a medicament for alleviating a symptom of Duchenne Muscular Dystrophy wherein the oligonucleotide inhibits or antagonises expression of BMP-4 in a cell. Also disclosed is an in vitro method for stimulating differentiation of a myoblast cell or precursor from an individual having Duchenne Muscular Dystrophy using a BMP-4 anti0sense oligonucleotide.
Patent NZ-579929-A (NZ)
Title: Improvements in water heaters
Inventor: ECHTNER GEORGE
IPC: F24H1/08
Filed: 2008-04-08
Abstract: A method of calibrating a water heater and a controller for a boiling water heater are disclosed. The controller (12) including a processor programmed to implement the method calibrating a water heater (100). The method comprises the steps of A. adding water to the tank to a first predetermined water level; B. heating the water to a first temperature threshold; C. maintaining the temperature at approximately the first temperature threshold for a first time period; D. heating the water until the rate of temperature change is less than a first predetermined rate; E. measuring the temperature (T1) of the water when the state of step D is achieved to determine a first iteration temperature.
Patent NZ-581369-A (NZ)
Title: Fermenter for generating biogas from pumpable organic material
Inventor: GANTEFORT WILHELM
IPC: B01J8/02
Filed: 2008-05-16
Abstract: A fermenter 10 for generating biogas from pumpable organic material with a low content of organic dry matter (oTS), comprises at least one inlet 11 for the pumpable organic material, at least one fixed bed reactor for the pump able organic material with at least one primary section 12a and one secondary section 12b, at least one outlet 20 for the remaining fermentation residue, at least one recycling section 15 for the pumpable material, the recycling section 15 being located between the primary and secondary section of the fixed bed reactor 10, and at least one sedimentation chamber 14 which is connected to the recycling section 15. The chamber 14 is designed in such a way that specific lighter fractions of the pumpable organic material can be recovered and, if required, can be re-supplied to the rising (primary) section 12a of the fixed bed reactor.
Patent NZ-589106-A (NZ)
Title: Substituted quinazolines
Inventor: GOLDING BERNARD
IPC: A61K31/517
Filed: 2009-05-13
Abstract: Provided is quinalonin compound of Formula (I) or a pharmaceutically acceptable salt or solvate thereof, substituted at positions 3 and /or 5 and with defined other substituents. The compound is a derivative of anagrelide, with improved properties and can be used to treat myeloproliferative diseases, high blood pressure and brondhodilation.
Patent NZ-591030-A (NZ)
Title: Combination of hcv ns3 protease inhibitor with interferon and ribavirin
Inventor: HUANG DAVID
IPC: A61K31/7056
Filed: 2009-09-14
Abstract: Disclosed is the use of a combination of: a compound of formula (1), interferon alpha, and ribavirin for the manufacture of a medicament for the treatment of hepatitis C virus (HCV) infection or alleviating one or more symptoms thereof. The compound of formula (1) is a selective and potent inhibitor of the HCV NS3 serine protease, and comprised quinoline, thiophene and cyclopropane moieties.
Patent NZ-596295-A (NZ)
Title: Anti-5T4 antibodies and uses thereof
Inventor: BOGHAERT ERWIN R
IPC: A61K39/395
Filed: 2007-03-09
Abstract: An anti-5T4 antibody that comprises a heavy chain variable region having the amino acid sequence of SEQ ID NO: 10 and a light chain variable region having the amino acid sequence SEQ ID NO: 12.
Patent NZ-596780-A (NZ)
Title: Immunoregulatory peptides and methods of use
Inventor: MCCOY SHARON L
IPC: A61K38/00
Filed: 2010-06-04
Abstract: Disclosed are peptides for the treatment of inflammation, and therapeutic uses and methods of using the same are disclosed. Peptides including a transducing sequence are effective for inhibiting cytokine activity and TNF-? secretion through interaction with toll-like receptors. Experiments are described illustrating the efficacy of the compounds in treating otitis media.
Patent NZ-601113-A (NZ)
Title: Carboxylic acid derivatives having a 2,5-substituted oxazolopyrimidine ring
Inventor: KADEREIT DIETER
IPC: A61K31/519
Filed: 2011-01-12
Abstract: 601113 Disclosed are oxazolo[5,4-d]pyrimidine compounds of formula (I) where the substituents are as disclosed in the specification. Examples of compounds of formula (I) are: [2,6-dimethyl-4-(5-phenoxy-oxazolo[5,4-d]pyrimidin-2-yl)-phenoxy]-acetic acid, (E)-3-{ 4-[5-(2-fluoro-phenoxy)-oxazolo[5,4-d]pyrimidin-2-yl]-phenyl} -acrylic acid, { 4-[5-(2,4-difluoro-phenoxy)-oxazolo[5,4-d]pyrimidin-2-yl]-2,6-dimethyl-phenoxy} acetic acid. The compounds are useful in treating wound healing in diabetes and the treatment of diabetic foot syndrome. Also disclosed are pharmaceutical compositions comprising a compound of formula (I).
Patent NZ-601523-A (NZ)
Title: Ruminant dietary supplement compositions and methods of manufacturing and using the same
Inventor: JOHNSTON JAMES D
IPC: A23K50/15
Filed: 2011-02-15
Abstract: Disclosed is a dietary supplement composition that is protein rich but not histidine-enriched, wherein the composition comprises about 5-10% nitrogen, about 30-60% crude protein, and about 0.5% to about 1.5% ammonia on a dry matter basis, and wherein said composition is made up of dried particles of 0.100-0.500 mm in size, and wherein said composition is free of a protective barrier derived from physical or chemical treatment of the composition.
Patent NZ-609023-A (NZ)
Title: Containers and seals therefor
Inventor: ELLIOTT HOWARD
IPC: B65D83/04
Filed: 2011-09-26
Abstract: 609023 Disclosed is a seal for use with a container and a container for storing and dispensing consumer products. The containers can be used in place of conventional blister packs for packaging of medication. Patients can experience difficulty with current seals associated with packaged medication. The seal is suitable for use with a container for storing and dispensing consumer products. The container includes a tray having a planar top surface into which has been formed one or more discrete cavities. The seal includes a cover film (1) which has a pattern of electrically conductive tracks (14) defining a circuit per cavity and preformed lines (4) of separation defining a removable portion (2) per cavity. Each removable portion (2) is attached to the remainder of the cover film (1) by a frangible bridge region defined by a gap in the associated pre-formed line (4) of separation which provides a pathway for the associated circuit.
Patent NZ-609141-A (NZ)
Title: Self-propelled orbital irrigator with speed-controlled sprinkler
Inventor: GARY JOHN BLEEKER
IPC: A01G25/09
Filed: 2009-10-07
Abstract: An orbital irrigator having the ability to travel in a circular direction around a central pivoting rotary joint, by means of two driven wheels (3) powered by a liquid powered driving mechanism (2), connected to a lateral arm (14) being also attached to a speed controlled rotating singular sprinkler nozzle (1) mounted upon the liquid powered driving mechanism. A liquid feed pipe (4), a stabiliser (13) and a lower half of the rotary joint, the feed pipe, stabiliser and rotary joint lower half each being stationary, provide a relocatable anchorage point forcing the orbital irrigator to travel in a circular direction around the anchorage point utilising the rotating driven wheels as the propelling method.
Patent NZ-616897-A (NZ)
Title: Foodstuff spread
Inventor: WASSELL PAUL
IPC: C11C3/02
Filed: 2012-06-08
Abstract: The disclosure relates to a foodstuff in the form of a spread, wherein the spread is a water in oil emulsion containing: (a) a continuous fat phase; and (b) a dispersed aqueous phase, wherein the spread comprises (i) triglycerides in an amount of from 41 to 90 wt.% based on the foodstuff; and (ii) a mono or di ester of glycerol and Moringa oil, wherein the mono or di ester of glycerol and Moringa oil is present in the high fat spread in an amount of from 0.01 to 2% w/w based on the total weight of the high fat spread.
Patent NZ-624510-A (NZ)
Title: Electrically stimulated respiratory assistance components
Inventor: FORMICA JUSTIN JOHN
IPC: A61M16/00
Filed: 2012-11-08
Abstract: Disclosed is a respiratory assistance component comprises a first and a second conduit that are each configured to supply breathable gas to an airway of a patient. The first and second conduits each comprises electro active polymer that causes the respective conduit to change shape and/or size between a first non-energized state, when no electrical voltage or current (126) is applied to the electro active polymer, and a second energized state, when voltage or current (126) is applied to the electro active polymer. The electro active polymer of the first conduit and the electro active polymer of the second conduit are selectively energisable so as to change the shape and/or size of the respective conduit so as to modify an aspect of the respiratory assistance provided to the patient.
Patent NZ-626744-A (NZ)
Title: Derivatives of aza adamantane and uses thereof
Inventor: RAO JAGANNATH MADANAHALLI RANGANATH
IPC: C07D471/08
Filed: 2012-12-21
Abstract: Disclosed herein are compounds of formula I where the substituents are as defined herein, that have the ability to inhibit 11-β-hydroxysteroid dehydrogenase type 1 (11β-HSD-1) and which are intended for use in the treatment of certain disorders that can be prevented or treated by inhibition of this enzyme. In addition the invention relates to the compounds, methods for their preparation, pharmaceutical compositions containing the compounds and the uses of these compounds in the treatment of certain disorders. It is expected that the compounds of the invention will find application in the treatment of conditions such as non-insulin dependent type 2 diabetes mellitus (NIDDM), insulin resistance, obesity, impaired fasting glucose, impaired glucose tolerance, lipid disorders such as dyslipidemia, hypertension and as well as other diseases and conditions. Examples of the compounds of formula I include 1-(2-azatricyclo[3.3.1.1 3,7]dec-2-yl)-3-(1H-indol-3-yl)propan-1-one and 1-(4-hydroxy-2-azatricyclo[3.3.1.1 3,7]dec-2-yl)-3-(1H-indol-3-yl)butan-1-one.
Patent NZ-630641-A (NZ)
Title: Alloy coated workpieces
Inventor: COOK PETER CHARLES
IPC: C23F17/00
Filed: 2013-12-12
Abstract: A process for cold welding, mechanical or peen plating a ferrous (iron) surface with a zinc powder coating to create a solid-solid diffusion alloy or intermetallic. The process includes adhering the coating to the iron substrate, heating the substrate to create the alloy, and subsequent cooling. The method works at lower temperatures than existing methods, thus using less energy.
Patent NZ-630700-A (NZ)
Title: Indole and indazole compounds that activate ampk
Inventor: BHATTACHARYA SAMIT KUMAR
IPC: C07D309/04
Filed: 2013-04-01
Abstract: Disclosed are 5-phenyl-indole-3-carboxylic acid derivatives as represented by general formula (II), wherein X is CH; L is a bond; R1 is -C(O)ORA; RA is H; R2 is H or F; R3 is Cl, F, or CN; R4 and R5 are H; R6 and R7 are independently H, F, or methoxy; R9 and R10 are H; R8 is alkoxy; hydroxyalkoxy; hydroxyalkyl; cyclopropyl or cyclobutyl substituted with hydroxy or hydroxyalkyl; hydroxyphenyl; azetidinyl, morpholinyl, oxetanyl, piperazinyl, piperidinyl, pyrrolidinyl, tetrahydrofuran, tetrahydro-2H-pyran, or triazolyl, wherein each of the heterocycles is optionally substituted with 1 substituent that is alkoxycarbonyl, alkyl, alkylcarbonyl, alkylsulfonyl, hydroxy, hydroxyalkyl, or oxo; heterocyclealkoxy, wherein the heterocycle is azetidinyl, morpholinyl, oxetanyl, piperazinyl, piperidinyl, pyrrolidinyl, tetrahydrofuran, tetrahydro-2H-pyran, or triazolyl, wherein each is optionally substituted with 1 substituent that is alkoxycarbonyl, alkyl, alkylcarbonyl, alkylsulfonyl, hydroxy, hydroxyalkyl, or oxo. Representative compounds include 6-chloro-5-(4-(1-hydroxycyclobutyl)phenyl)-1H-indole-3-carboxylic acid, 6-fluoro-5-(4-(1-hydroxycyclobutyl)phenyl)-1H-indole-3-carboxylic acid, 4,6-difluoro-5-[4-(1-hydroxy-2-methylpropan-2-yl)phenyl]-1H-indole-3-carboxylic acid, 4,6-difluoro-5-(4-(1-(hydroxymethyl)cyclobutyl)phenyl)-1H-indole-3-carboxylic acid, 6-chloro-5-[3-fluoro-4-(1-hydroxy-2-methylpropan-2-yl)phenyl]-1H-indole-3-carboxylic acid, 4,6-difluoro-5-{ 4-[1-(hydroxymethyl)cyclobutyl]phenyl)-1H-indole-3-carboxylic acid, 4,6-difluoro-5-[4-(tetrahydro-2H-pyran-2-yl)phenyl]-1H-indole-3-carboxylic acid, 6-fluoro-5-[4-(tetrahydro-2H-pyran-2-yl)phenyl]-1H-indole-3-carboxylic acid, 6-chloro-5-{ 4-[tetrahydro-2H-pyran-2-yl]phenyl} -1H-indole-3-carboxylic acid and 6-chloro-5-[4-(oxetan-2-ylmethoxy)phenyl]-1H-indole-3-carboxylic acid. Also disclosed is a pharmaceutical composition comprising a compound as defined above and at least one pharmaceutically acceptable excipient, diluent, or carrier, for treating or preventing chronic kidney disease, diabetic nephropathy, acute kidney injury, polycystic kidney disease, Type II diabetes, dyslipidemia or obesity in a mammal.
Patent NZ-727997-A (NZ)
Title: Structural element
Inventor: MELLAND TRISTAN
IPC: E04C2/34
Filed: 2015-06-03
Abstract: A structural element (10) is made from sheet material that is deformed at intervals along its length and width to provide pods (16) that protrude from the plane of the sheet. The walls of the pods (16) slope obliquely relatively to the plane of the sheet. At least two sheets (12, 14) are formed with such pods, and two of the sheets are juxtaposed to each other in mirror-image, or facing, fashion, with floors of the pods engaging in contact zones. The walls of engaged pods (16) form diamond beam formations with adjacent engaged pods such that multiple diamond beam structures are formed in the structural element in the negative spaces immediately between pairs of engaged pods. A related structural element is in the form of a structural panel consisting of two outer sheets that act as the tensile and compression chords, both with multiple inwardly orientated pods throughout the panel and whose inward orientated apexes are joined together and which have a close proximity one to another in order to be mechanically interdependent creating a double depth space-frame lattice type matrix where loads placed on the panel’s surface are resisted and transferred through the chords. The pods act as interconnecting diagonal braces. The walls of joined pods form diamond beam formations with adjacent joined pods such that multiple diamond beam structures are formed in the structural element in the negative spaces immediately between pairs of joined pods. Also provided is a method of producing the structural element 10 via a pressing method. The invention addresses the problem of the creation of a structural element where, compared to a sheet of material, the strength can be increased without the addition of further material and weight. The proximity of the pods results in the joined points of the diamond beam structure and provides the necessary strength for the structural element.
Patent NZ-731512-A (NZ)
Title: Compositions comprising cyclosporin
Inventor: COULTER IVAN
IPC: A61K9/107
Filed: 2015-11-06
Abstract: The present invention relates to a formulation comprising a pharmaceutically active ingredient, a hydrogel forming polymer matrix, a surfactant and an oil phase being dispersed in the hydrogel forming polymer matrix, and coating. The invention also relates to the use of the formulation in the treatment and prevention of disorders of the gastrointestinal tract. Also disclosed are methods for preparing the formulations.
Patent NZ-735290-A (NZ)
Title: Enhanced delivery of viral particles to the striatum and cortex
Inventor: STANEK LISA
IPC: C12N15/86
Filed: 2016-02-09
Abstract: Provided herein are novel methods for delivering recombinant adeno-associated viral (rAAV) particles to the central nervous system of a mammal (e.g., a human). In aspects, the methods involve administering rAAV particles containing a heterologous nucleic acid to the striatum and causing expression of the heterologous nucleic acid in at least the cerebral cortex and the striatum of the mammal.
Patent NZ-741758-A (NZ)
Title: Culinary seasoning or bouillon tablet
Inventor: HABEYCH NARVAEZ EDWIN ALBERTO
IPC: A23L7/10
Filed: 2016-10-31
Abstract: The present invention relates to a seasoning or bouillon tablet used as cooking aid for the preparation of culinary food products. The seasoning or bouillon tablet comprises salt, oil and/or fat and a culinary flavoring, characterized in that the tablet further comprises 5 to 25 dry wt% of a cereal bran.
Patent NZ-752829-A (NZ)
Title: Animal spraying devices, systems and methods of use
Inventor: AVILA VERNON
IPC: A01K7/02
Filed: 2018-02-08
Abstract: A method and apparatus for spraying animals in hot or dry weather comprising the steps of: a. detecting that pressure from a water source has reached a threshold level, and activating a microprocessor when said threshold is reached; b. while said pressure is at or above-said threshold level, i. said microprocessor activating a proximity sensor for detecting the presence of an animal in a given area; ii. said microprocessor opening a valve to a water sprayer if at least one animal of sufficient size is detected by said proximity sensor, and closing said valve if said at least one animal is no longer detected; and c. when said water pressure drops below-said threshold level, i. said microprocessor deactivating said proximity sensor, and ii. said microprocessor closing said valve.
Patent NZ-759411-A (NZ)
Title: Pharmaceutical compositions comprising dimethyl fumarate
Inventor: PLANELLS JIMENEZ MARIA
IPC: A61P37/00
Filed: 2014-12-05
Abstract: Pharmaceutical compositions are described comprising (a) dimethyl fumarate, (b) a diluent selected from monosaccharides, disaccharides, starch and starch derivatives, calcium and magnesium inorganic salts, sugar alcohols, and mixtures thereof, (c) microcrystalline cellulose and (d) croscarmellose sodium, wherein the dimethyl fumarate is not covered with a gastro-resistant coating. These compositions are intended for the treatment of some inflammatory autoimmune diseases or disorders.
Patent NZ-773759-A (NZ)
Title: Respiratory pressure therapy device
Inventor: SHADIE TIMOTHY NICHOLAS
IPC: A61M16/00
Filed: 2016-03-14
Abstract: Apparatus for generating a supply of air at positive pressure for the amelioration or treatment of a respiratory disorder, comprising: a first chamber; a second chamber; a plurality of inlet tubes structured and configured to allow ambient air to enter the first chamber; a plurality of flow tubes structured and configured to allow air to pass from the first chamber to the second chamber; a blower structured and configured to produce a flow of air at positive pressure, wherein the blower is positioned in the first chamber and structured and configured to receive air from the second chamber; an inlet end suspension to support the blower adjacent a blower inlet of the blower; and an outlet end suspension to support the blower adjacent a blower outlet of the blower, wherein the first chamber, the second chamber, the inlet tubes, the flow tubes, and the blower are arranged to form an air flow path extending from an inlet to the blower inlet of the blower and from the blower outlet of the blower to an outlet, wherein the air flow path includes a general U-shape from the inlet to the outlet.
Patent NZ-779017-A (NZ)
Title: Mutated acetohydroxyacid synthase genes in brassica
Inventor: SCHOPKE CHRISTIAN
IPC: A01H1/00
Filed: 2008-10-03
Abstract: Disclosed is an isolated nucleic acid encoding a Brassica acetohydroxyacid synthase (AHAS) protein comprising a mutation at one or more amino acid positions corresponding to a position selected from the group consisting of: A205, D376, W574, R577, and S653 of SEQ ID NO: 1.
Patent PT-101965-A (PT)
Title: New stable pharmaceutical formulations of microgranules containing omeprazole
Inventor: REIS ANA CATARINA FERNANDES RO
IPC: A61K31/415
Filed: 1997-02-06
Abstract: The present invention deals with new stable pharmaceutical formulations containing omeprazole. The formulations contain omeprazole in a quantity comprised between 1 mg and 50 mg and consist of an inert core consisting of starch and sugar, coated with a layer containing omeprazole, the latter being in turn coated with an insulating layer which, finally, is coated with a gastro-resistant layer. The pharmaceutical product is free of organic solvents and/or impurities generally associated with them, because the application of the various layers makes use of aqueous solvents alone. The resulting product is stable for a period of time consistent with pharmaceutical requirements and presents gastro-resistance and dissolving characteristics adequate for the shelf life generally established for the product, three years.
Patent PT-103806-A (PT)
Title: Utilização de óleos essenciais extraídos de viburnum tinus l. subsp. subcordatum (trelease) p. silva como agente antimicrobiano e antitumural
Inventor: MEDEIROS JORGE MANUEL ROSA DE
IPC: A61K36/185
Filed: 2007-08-09
Abstract: DIZ RESPEITO A COMPOSIÇÕES QUÍMICAS DE ORIGEM NATURAL, OBTIDAS A PARTIR DE FOLHAS DE V. TINUS SUBS. SUBCORDATUM POR HIDRODESTILAÇÃO, E QUE ACTUAM DE FORMA BIOCIDA OU BIOSTÁCTICA SOBRE MICRORGANISMOS E LINHAS TUMURAIS. OS ÓLEOS DAS COMPOSIÇÕES BIOCIDAS OU BIOSTÁTICAS SÃO EXTRAÍDOS DE VIBURNUM TINUS L. SUBSP. SUBCORDATUM (TRELEASE) P. SILVA, E TÊM ACTIVIDADE CONTRA AS BACTÉRIAS LYSTERIA MONOCYTOGENES, ESCHERICHIA COLI, OS FUNGOS CANDIDA ALBICANS E CANDIDA GLABRATA, E AINDA CONTRA AS LINHAS TUMORAIS HELA (CANCRO DO COLO DO ÚTERO) E HEP2 (CANCRO DA LARINGE). ESTAS COMPOSIÇÕES REVELAM GRANDE UTILIDADE NAS INDÚSTRIAS FARMACÊUTICA E AGRO-ALIMENTAR.
Patent PT-103978-A (PT)
Title: Blocos de encaixe e processo para construção de edificações empregando esses blocos
Inventor: GONCALVES JOAQUIM A
IPC: E04B2/08
Filed: 2008-02-27
Abstract: A PRESENTE INVENÇÃO REFERE BLOCOS DE ENCAIXE PARA ALVENARIAS EXTERIORES, INTERIORES, PROCESSO DE CONSTRUÇÃO E/OU AUTO-CONSTRUÇÃO. ESTES BLOCOS CONSTITUEM UM SISTEMA MODULAR DE ENCAIXE NOS QUATROS LADOS, DERIVADOS DO BLOCO PRINCIPAL. ESTE E SUAS VARIANTES PRETENDEM ABRANGER TODAS AS HIPÓTESES DE APLICAÇÃO EM CONSTRUÇÃO. A INVENÇÃO PERMITE: CONSTRUÇÃO DE ALVENARIA DE ENCHIMENTO INTER-ESTRUTURAL DE GRANDES EDIFICAÇÕES COM ESTRUTURAS EM BETÃO ARMADO OU AÇO; MANUSEAMENTO DOS BLOCOS DE FORMA RÁPIDA, EFICIENTE REDUZINDO ESFORÇO FÍSICO OU MECÂNICO, REDUZINDO O SEU PESO; PROPORCIONAR ENCAIXES NAS FACES DE JUNTA DOS BLOCOS, PARA QUE SE MONTEM E JUSTAPONHAM COM FACILIDADE E RAPIDEZ; PROPORCIONAR O EFICAZ TRAVAMENTO DOS BLOCOS ATRAVÉS DOS ENCAIXES E A ELIMINAÇÃO DO ASSENTAMENTO COM ARGAMASSAS; POSSIBILITAR A CRIAÇÃO DE ESTRUTURAS CONSTITUÍDAS POR PILARES E VIGAS INTEGRADOS NAS ALVENARIAS; TORNAR POSSÍVEL A INTEGRAÇÃO DE CANALIZAÇÕES NAS ALVENARIAS; REFORÇAR O ISOLAMENTO TÉRMICO E SONORO, ATRAVÉS DE PAREDE DUPLA, PERMITINDO A EXISTÊNCIA DE UMA CAIXA-DEAR.