baber/WOPTO huggingface dataset:
Patent CA-2980692-A1 (CA)
Title: Method of spot welding
Inventor: MIYAZAKI YASUNOBU
IPC: B23K11/16
Filed: 2016-03-30
Abstract: Provided is a spot welding method with which liquid metal embrittlement cracking during spot welding of a plated steel sheet can be easily prevented, wherein the method is characterized in that, prior to spot welding, the plating is removed in at least: a range which is centered at the planned location where the center of the nugget is to be formed, the outer perimeter of the range including the interior of a circle inside the outside edge of the weld-affected part; or, from a superposition surface of the welded steel sheet, a range which has a center in common with the planned location at which the center of the nugget formed on the superposition surface of the welded steel sheet is to be formed, the outer perimeter of the range including the interior of a circle inside the outside edge of the weld-affected part.
Patent CA-2982694-A1 (CA)
Inventor: MACGREGOR ALEXANDER JOHN
IPC: E21B21/08
Filed: 2016-04-13
Abstract: A riser pressure relief apparatus comprising a tubular riser having a main passage and a side port to connect the main passage with the exterior of the riser, a pressure relief valve including a valve member which is movable between a first position in which the valve member substantially prevents flow of fluid through the side port and a second position in which flow of fluid through the side port is permitted, a hydraulic actuator (10) which is operable to move the valve member, a source of pressurised fluid (12), and a pilot valve assembly controlling the flow of pressurized fluid to the actuator, wherein the pilot valve assembly includes a valve part (14) which is fluidly connected to the main passage of the riser and moves from a first position to a second position when the fluid pressure in the main passage of the riser exceeds a predetermined amount.
Patent CA-2983753-A1 (CA)
Inventor: WALTERS DAVID
IPC: C09D201/02
Filed: 2016-05-11
Abstract: A curable film-forming composition is provided, comprising: (a) a curing agent comprising reactive functional groups; (b) a compound comprising functional groups reactive with the reactive functional groups in (a); and (c) a photothermally active material. The composition may further include a catalyst component. Coated substrates are also provided using the compositions described, as well as methods for coating a substrate using the compositions.
Patent CA-2983971-A1 (CA)
Inventor: COX CHRISTOPHER PAUL
IPC: B62D7/22
Filed: 2017-10-27
Abstract: Generally described, aspects of the disclosed subject matter are directed to through-shaft dampers. In accordance with aspects of the present disclosure, the through-shaft dampers generally include a shaft having a piston traveling within a body, a first chamber for a damping fluid, and a second chamber for a gas. The chambers are separated by a movable wall associated with an insert and configured to provide a volumetric change of the second chamber that is inverse to a volumetric change of the damping fluid. The insert is configured such that the sealing surfaces of the movable wall do not interface the shaft during use of the damper. In this regard, a significant reduction in the total displacement traveled by the seals is realized.
Patent CA-2986687-A1 (CA)
Title: Fabrication de vaccins multidoses prets a injecter a base de cellules dendritiques
Inventor: CZERNIECKI BRIAN J
IPC: A61K39/395
Filed: 2016-03-05
Abstract: Les présents modes de réalisation concernent un vaccin injectable multidose approuvé par la FDA à base de cellules dendritiques (CD) à impulsions antigéniques. Dans un mode de réalisation, le vaccin à base de CD chargées d'antigènes activés comprend une dose d'immunisation initiale et plusieurs doses de rappel. L'invention concerne également un procédé de traitement permettant d'inhiber à la fois HER-2 et HER-3, ce qui provoque une sénescence permanente de la tumeur dans les cancers du sein exprimant HER-2. L'invention concerne également un traitement combiné associant thérapie anti-strogénique et vaccination anti-HER2 à base de cellules dendritiques pour les patients atteints d'un cancer du sein de type carcinome canalaire in situ ERpos/HER2pos.
Patent CA-2989404-A1 (CA)
Inventor: DENBOER HUIBERT
IPC: H04W4/21
Filed: 2016-05-26
Abstract: Methods and apparatuses for establishing a wireless connection are disclosed. In an embodiment, a first communication device transmits a first advertising signal for a first period of time, the first advertising signal configured to advertise that the first communication device is available to establish a first wireless connection, scans for a second advertising signal for a second period of time, the second advertising signal transmitted by a second communication device and configured to advertise that the second communication device is available to establish a second wireless connection, and listens for a third signal for a third period of time, the third signal transmitted by a third communication device in response to the first advertising signal, the third period of time occurring during the second period of time.
Patent CA-2991723-A1 (CA)
Inventor: BALATCHEV STEFAN
IPC: G08B23/00
Filed: 2018-01-15
Abstract: A resistance temperature detector (RTD) emulator that provides a low-power, variable resistance output that is indicative of a state of a monitored sensor. The RTD-output emulator is integrated into the existing infrastructure of the process control of an industrial site. The emulator output reflects the reading of the monitored sensor and this output is compatible with RTD-input devices (i.e., the output is reflected through a variable resistance).
Patent CA-2994238-A1 (CA)
Title: Commutateur d'identification par radiofrequence (rfid) rotatif
Inventor: BARNEY CLIFFORD S
IPC: H04Q5/22
Filed: 2016-07-29
Abstract: L'invention concerne divers modes de réalisation de procédés et d'appareils impliquant une identification par radiofréquence (RFID). Un mode de réalisation de procédé, parmi d'autres, consiste à recevoir un signal d'excitation au niveau d'un commutateur rotatif associé à une pluralité d'étiquettes d'identification par radiofréquence (RFID) et un matériau de masquage radiofréquence (RF), et orienter le matériau de masquage RF par rapport à toutes les étiquettes RFID de telle sorte qu'une étiquette RFID est rendue détectable par un lecteur RFID à proximité.
Patent CA-2997203-A1 (CA)
Title: Procede de preparation de promedicaments de phosphoramidate de nucleoside et produits intermediaires correspondants
Inventor: YUAN JIANDONG
IPC: C07F9/24
Filed: 2016-09-13
Abstract: La présente invention se réfère à un nouveau procédé de préparation de promédicaments de phosphoramidate de nucléoside et à des produits intermédiaires correspondants. En particulier, le procédé permet de mettre en oeuvre une séparation d'isomères sur un produit de réaction issu d'une première étape, et de mettre ensuite en oeuvre une synthèse chimique en deux étapes afin de préparer un composé de pureté élevée Sp-1. Le procédé, simple et pratique, présente un faible coût. L'isomère unique Sp-1 résultant ainsi préparé présente une pureté élevée, sa pureté HPLC est supérieure à 95 %, et en particulier supérieure à 99 %. Le procédé convient pour une production industrielle et peut répondre aux exigences d'études cliniques. De plus, la présente invention concerne également un réactif intermédiaire du phosphore essentiel en vue de la préparation du composé de pureté élevée Sp-1 et un procédé de préparation correspondant.
Patent CA-2999355-A1 (CA)
Inventor: SHOLEV MORDEHAI
IPC: A61B17/00
Filed: 2008-10-22
Abstract: The present invention provides a fixating means adapted for use in hernia repair surgeries in attaching a mesh and mesh deployment means; said fixating means are attached to said mesh deployment means; said fixating means comprising: (a) a first portion coupled to said deployment means; and, (b) a second portion, comprising a coil having a predetermined retracted shape; said coil is reconfigurable from a plurality of unretracted positions to a plurality of retracted positions and from said plurality of retracted positions to said plurality of unretracted positions; wherein said attachment between said deployment means and said mesh is obtained by reconfiguration of said coil from at least one of said unretracted positions to at least one of said retracted positions.
Patent CA-3000170-A1 (CA)
Inventor: QUAKE STEPHEN R
IPC: C12N9/22
Filed: 2016-05-27
Abstract: The invention relates to systems and methods for removing viral genetic sequences from host genomes by using a computer system to read a nucleotide string next to a protospacer adjacent motif (PAM) in the viral sequence, determine that the host genome lacks any region that matches the nucleotide string according to a predetermined similarity criteria and is adjacent to the PAM, and provide a guide sequence at least partially complementary to the nucleotide string. Providing the guide sequence may include synthesizing a guide RNA that includes a portion that is complementary to the nucleotide string.
Patent CA-3004644-A1 (CA)
Inventor: XU YILING
IPC: H04N21/84
Filed: 2016-02-02
Abstract: A method for implementing personalized presentation of associated multimedia content, and an application. The method is specifically: a multimedia content provider completes full file content in a unified manner when creating a multimedia file, and meanwhile grades fragments in the content according to the importance and/or association of the content by means of labeling, so as to produce different versions of multimedia files; and a user performs selective preview and/or play according to the versions. The method is a flexible, efficient and scalable organization, storage and transmission method in an Internet on demand system, so as to add a flexible media content organization mechanism that is absent in existing multimedia protocols, and solve the problems of low transmission efficiency, storage resource waste and poor user experience in existing multimedia systems.
Patent CA-3006563-A1 (CA)
Title: Compositions and methods for otologic prophylaxis and treatment
Inventor: Turkel Catherine Crisp
IPC: A61K9/00
Filed: 2016-11-30
Abstract: A prophylactic method for preventing otitis media or Eustachian tube dysfunction, or reducing the severity of symptoms thereof, decreasing the risk of future otitis media, with or without ear infection, and associated effects including acute or permanent hearing loss, speech and balance problems, behavior problems and sleep problems caused by acute, intermittent episodic, recurrent or chronic otitis media, and the need for surgical interventions involving myringotomy such as ear tubes for chronic middle ear effusions, or tympanic membrane perforation for acute drainage of effusion from the middle ear and ventilation of the middle ear, through the nasal delivery of surfactant to the Eustachian tube(s).
Patent CA-3007486-A1 (CA)
Title: Multibeam element-based backlight and display using same
Inventor: FATTAL DAVID A
IPC: G02B27/42
Filed: 2016-06-08
Abstract: A multiview backlight and a multiview display employ multibeam elements configured to provide a plurality of light beams having different principal angular directions corresponding to different view directions of the multiview display. The display includes multiview pixels that include sub-pixels. A size of the multibeam element is comparable to a size of a sub-pixel in a multiview pixel of the multiview display.
Patent CA-3011126-A1 (CA)
Inventor: GOVARI ASSAF
IPC: H02J7/00
Filed: 2018-07-12
Abstract: Apparatus, consisting of a power supply having a first electrical connection to a relatively high voltage source and connectable to ablation circuitry in a catheter via a second electrical connection. There are rechargeable first and second subsidiary power sources in the power supply. The apparatus also has a control unit, and a first switch alternately connecting the ablation circuitry to the first and second subsidiary power sources responsively to control signals from the control unit. The apparatus also has a second switch alternately connecting one of the first and second subsidiary power sources to the high voltage source for recharging thereof responsively to the control signals while the one of the first and second subsidiary power sources is disconnected from the ablation circuitry and another of the first and second subsidiary power sources is connected to the ablation circuitry by the first switch.
Patent CA-3011238-A1 (CA)
Inventor: COHN WILLIAM E
IPC: A61M25/06
Filed: 2017-01-15
Abstract: La présente invention concerne des systèmes et des procédés destinés à positionner un fil pour le faire avancer à travers une paroi de vaisseau, et le faire avancer à travers une ou plusieurs parois de vaisseaux, qui comprennent généralement un cathéter de pose et un cathéter d'alignement ou un cathéter de réception, et un fil de guidage. Dans certaines variantes, les systèmes et les procédés peuvent être utilisés pour contourner une occlusion ou une autre barrière qui peut empêcher de faire avancer un fil ou des outils à travers un espace endoluminal. Dans ces variantes, les systèmes et les procédés comprennent un cathéter de pose, un cathéter de contournement, un cathéter de réception, et un fil de guidage. Les cathéters de pose et de réception comprennent chacun généralement une ouverture latérale, une surface de déflexion, et un élément d'alignement, et le cathéter de contournement comprend généralement deux ouvertures latérales, deux déflecteurs, et deux éléments d'alignement. Dans certaines variantes, les systèmes et les procédés peuvent faciliter le traitement d'un patient souffrant d'une ischémie critique des membres.
Patent CA-3012743-A1 (CA)
Title: Portable attachment of fiber optic sensing loop
Inventor: NGUYEN GARY
IPC: E21B47/01
Filed: 2014-02-24
Abstract: The subject matter of this specification can be embodied in, among other things, a system for removably attaching an optical fiber sensor loop onto a tubular member, which includes an optical fiber sensor loop having a continuous optical fiber positioned arranged in a plurality of loops, each of said loops having a first end turn and a second end turn, a first and a second turn guide each including a plurality of turn grooves increasing outwardly in increasing radii, each of said turn grooves configured to receive an end turn portion of the optical fiber, a first and a second mounting wedge each having a planar first surface configured to receive a turn guide and a curved second surface configured to be received on the tubular member, and a connector configured to couple the first mounting wedge to the second mounting wedge.
Patent CA-3012951-A1 (CA)
Inventor: PENA CAROL
IPC: C12Q1/68
Filed: 2017-01-31
Abstract: This invention provides biomarkers based on the gene expression profiling which can discriminate between patients who response to and/or with longer progression free survival and patients who do not response to and/or with shorter progression free survival from copanlisib treatment in lymphoma including indolent and aggressive NHLs and CLLs. The present invention relates to the use of genes from the BCR, PI3K, NFkB, IL6, inflammation and stromal processes as predictive biomarkers for various human cancers including but not limited to NHLs.
Patent CA-3014560-A1 (CA)
Inventor: PENG YUXING
IPC: G01N3/56
Filed: 2017-12-04
Abstract: A self-detection device for a middle trough of a scraper conveyor and a detection method is disclosed. The device comprises a frame, a baffle hoist conveyor. a horizontal conveyor, a loading hopper, an unloading hopper, and a sliding friction mechanism. A liner and an eccentric motor are mounted in the sliding friction mechanism. The eccentric motor is slidably connected to a scraper through a slide bar.  The scraper is disposed on the liner, and an impact force sensor is disposed on the scraper. A pull-pressure sensor is mounted on the slide bar. The self-detection device for a middle trough can simulate the wear behavior from impact and friction between a scraper and a middle trough of a scraper conveyor, and can measure in real time an impact force applied to the scraper as materials fall and a frictional force between the scraper and the liner and a friction factor.
Patent CA-3019145-A1 (CA)
Inventor: LI YUN-LONG
IPC: A61K31/519
Filed: 2017-03-27
Abstract: Cette application décrit des composés de Formule I : et des sels acceptables sur le plan pharmaceutique, qui sont des inhibiteurs de kinases TAM et peuvent ainsi être utiles dans le traitement de maladies comme le cancer. Dans certaines réalisations, il est décrit des composés de Formule (llbl) ou (llb2) : et des sels acceptables sur le plan pharmaceutique.
Patent CA-3022649-A1 (CA)
Inventor: MULLER BERNHARD
IPC: B23P15/00
Filed: 2017-03-29
Abstract: L'invention concerne un procédé de fabrication d'un élément de raccordement tubulaire cintré, qui comprend au moins les étapes de fabrication suivantes consistant : à réaliser un usinage par enlèvement de copeaux sur une pièce tubulaire (10) métallique rectiligne d'une longueur prédéfinissable en prenant en compte des géométries de raccordement (12, 14) destinées à recevoir des éléments de raccordement séparés (18, 20) servant au raccordement d'un tubage d'acheminement de fluide, à réaliser un cintrage sur la pièce tubulaire (10) créée par enlèvement de copeaux avec un rayon de cintrage prédéfinissable, de préférence de 90 degrés maximum, et à monter l'élément de raccordement respectif (18, 20) sur la géométrie de raccordement d'extrémité associable (12, 14) de la pièce tubulaire (10).
Patent CA-3023984-A1 (CA)
Inventor: SKOKOS DIMITRIS
IPC: A61N5/00
Filed: 2017-05-12
Abstract: The present disclosure provides methods for treating, reducing the severity, or inhibiting the growth of cancer (e.g., solid tumors). The methods of the present disclosure comprise administering to a subject in need thereof a therapeutically effective amount of a programmed death 1 (PD-1) antagonist (e.g., an anti-PD-1 antibody), optionally, in combination with radiation therapy. In certain embodiments, the methods comprise administering hypo-fractionated radiation in combination with an anti-PD-1 antibody or a fragment thereof to achieve a prolonged abscopal effect in tumor inhibition.
Patent CA-3024436-A1 (CA)
Inventor: MOLOODI SINA
IPC: B61F5/04
Filed: 2018-11-16
Abstract: A rail road car truck has a bolster having the form of a hollow beam that has a deep central portion and shallow ends. The bolster has a top flange, a bottom flange and internal and external webs extending between, intersecting and merging with the top and bottom flanges. A center plate bowl is located in the middle of the top flange, and brake rod passages are defined transversely through the bolster. In some embodiments, transverse ribs run underneath the center plate bowl. The ribs may be curved. The ribs may be flush with the brake rod openings in the various webs. There may be upwardly standing ribs running transversely across the bottom flange. Those lower ribs may terminate upwardly flush with the brake rod openings. Alternatively, the bottom portion of the bolster may by cast with a greater thickness, up to the bottom of the break rod openings. In other embodiments, the bolster may have partial or fully tubular brake rod opening liners or tubes that extend across the bolster beneath the center plate.
Patent CA-3025434-A1 (CA)
Inventor: SNYDER KRISTINA
IPC: A61F2/46
Filed: 2017-06-01
Abstract: Disclosed is a system for trialing implants used in orthopedic surgery. The invention is directed to a composite trial implant that employs a polymer substrate having a size and shape to approximate a bone plate, and radio-opaque indicia disposed thereon. The trial implant allows a surgeon to determine the correct size, hole configuration, and cross-sectional profile with a simulated device, that permits more rapid and accurate selection of a permanent implant.
Patent CA-3025754-A1 (CA)
Inventor: NODA KUNIAKI
IPC: G01C21/26
Filed: 2016-05-30
Abstract: An object detection method according the present invention includes: acquiring three-dimensional data on an area around a host vehicle by use of a distance measurement sensor; based on map data on an area around a current position of the host vehicle, setting a planned travel area where the host vehicle is going to travel in the future; estimating crossing object existence areas where there currently exist objects which are likely to cross the host vehicle in the future in the set planned travel area; and detecting the object by use of the three dimensional data on insides of the estimated crossing object existence areas.
Patent CA-3026220-A1 (CA)
Inventor: MURRAY GEORGE M
IPC: C08J3/24
Filed: 2016-06-02
Abstract: Ion exchange resin macroporous beads for the highly selective extraction of univalent anions from aqueous solutions. A specific example is the removal of dicyanoaurate and dicyanoargentate from cyanide leach solutions and tailings. The beads have a maximum number of ligands specific for the desired univalent anion, while maintaining sufficient separation to minimize binding of polyvalent ions. The beads are prepared using a functionalized monomer with the use of a specifically tuned coordinator. The beads can be used as a sensor for detecting the amount of anions captured when interrogated by an appropriate light source.
Patent CA-3027396-A1 (CA)
Inventor: BEWLAY BERNARD PATRICK
IPC: B22C1/00
Filed: 2014-11-05
Abstract: The disclosure relates generally to mold compositions and methods of molding and the articles so molded. More specifically, the disclosure relates to silicon carbide-containing mold compositions, silicon carbide-containing intrinsic facecoat compositions, and methods for casting titanium-containing articles, and the titanium-containing articles so molded. A slurry containing silicon carbide and calcium aluminate is introduced in a mold cavity that contains a fugitive pattern. The slurry is cured in the mold, sintered and used for casting a titanium turbine blade.
Patent CA-3027435-A1 (CA)
Title: Methods and systems for detecting and quantifying peroxyacid and peroxide in fluids
Inventor: RICHARDSON JOHN
IPC: C12Q1/30
Filed: 2017-07-19
Abstract: Methods and systems are disclosed for analyzing and treating a fluid containing a peroxyacid and/or peroxide. Method of analyzing the fluid includes introducing into the fluid a decomposition agent that catalyzes decomposition of the peroxyacid and/or peroxide into decomposition products including oxygen, then directly or indirectly measuring an amount of oxygen produced after introduction of the decomposition agent, and determining an amount of the peroxyacid and/or peroxide present in the fluid. The amount of peroxyacid and/or peroxide in the fluid can also be monitored and controlled by further adjusting the amount of the peroxyacid and/or peroxide in the fluid based on the determined amount thereof. A system for performing the methods includes a decomposition agent infusion device for introducing the decomposition agent into a fluid sample, and a sensor for directly or indirectly measuring an amount of oxygen produced after introduction of the decomposition agent.
Patent CA-3027651-A1 (CA)
Inventor: CONG FENG
IPC: A61K39/395
Filed: 2017-06-13
Abstract: The present invention relates methods of treatment using BMP6 antagonists.