baber/WOPTO huggingface dataset:
Patent EC-SP972114-A (EC)
Title: Biarilacetilenos como inhibidores de la metaloproteasa de matriz
Inventor: CHEN JINSHAN
IPC: C07C209/00
Filed: 1997-05-12
Abstract: Se presentan compuestos inhibidores de la metaloproteasa de matriz, composiciones farmacéuticas de los mismos y un método de tratamiento de enfermedades mediante el uso de dichos compuestos. Los compuestos de la presente invención tiene la fórmula generalizada (gráfico), donde R15 es seleccionado entre el grupo que consiste en HOCH2, MEOCH2, (N-Pr)2Nch2, CH3CO2CH2, EtOCO2CH2, HO(CH2)2CH3CO2 (CH2)2, HO; C(CH2)2, OHC(CH2)3, HO(CH2)4, Ph, y 3 -HO-Ph, y Ph y PhCH2OCH2:y (gráfico), Estos compuestos son útiles para inhibir las metaloproteasas de matriz y, por lo tanto, para combatir los trastornos a los cuales contribuyen las MMP, tales como la osteoartritis reumatoidea, la artritis séptica, las enfermedades periodontales, las úlceras de córnea, la proteinuria, la enfermedad de aneurisma aórtico, la epidermólisis vesicular distrófica, los trastornos que producen respuestas inflamatorias, la osteoporosis en las que media la actividad de MMP, la enfermedad de la articulación temporomandibular, las enfermedades desmielinizantes del sistema nervioso; las metástasis de tumores o la pérdida degenerativa de cartilago posterior a la lesión articular traumática, y la trombosis coronaria a partir de la ruptura de placa ateroesclerótica. La presente invención presenta asi mismo composiciones farmacéuticas y métodos para tratar dichos trastornos.
Patent EC-SP993164-A (EC)
Title: Nuevos antibioticos macrolidos
Inventor: KANEKO TAKUSHI
IPC: C07G11/00
Filed: 1999-10-04
Abstract: Esta invención se refiere a compuestos de fórmula (gráfico), en la que a, R1, R2, R3, R4, R5, R6 y X son cada uno como se han definido antes, y a sus sales farmacéuticamente aceptables, útiles como potentes agentes antibacterianos y antiprotozoos que se pueden usar para tratar diversas infecciones bacterianas y provocadas por protozoos y trastonos relacionados con dichas infecciones. La invención también se refiere a composiciones farmacéuticas que contienen los compuestos de fórmula I y a procedimientos para tratar infecciones bacterianas y provocadas por protozoos administarndo los compuestos de fórmula I.
Patent FI-20021983-A (FI)
Inventor: GUEVORKIAN DAVID
IPC: G06F17/16
Filed: 2002-11-06
Abstract: The present invention relates to a method for performing calculation operations using a pipelined calculation device comprising a group of at least two pipeline stages. The pipeline stages comprise at least one data interface for input of data and at least one data interface for output of data. In the method, data for performing calculation operations is input to the device. Selective data processing is performed in the calculation device, wherein between at least one input data interface and at least one output data interface a selection is performed to connect at least one input data interface to at least one output data interface for routing data between at least one input data interface and at least one output data interface and for processing data according to the selection. The invention further relates to a system and a device in which the method is utilized.
Patent FI-20031818-A (FI)
Inventor: PERE JAAKKO
IPC: D21B1/02
Filed: 2003-12-11
Abstract: The invention relates to a method for the pre-treatment of chips, which can be used to reduce the specific energy consumption of mechanical pulp and to improve the technical properties of the fibres. In the treatment, chips in a liquid phase are brought into contact with an enzyme preparation containing cellobiohydrolase and endoglucanase
Patent GB-1051099-A (GB)
IPC: G01F11/10
Abstract: 1,051,099. Sowing seeds in pots. W. S. BENTLEY. Oct. 13, 1965 [July 17, 1964], No. 29236/64. Heading A1D. [Also in Division B8] An apparatus for delivering measured quantities of material, such as peat moss, to containers C comprises a hopper 2 from which the material is fed between a pair of drums 9, 10 adapted to be rotated in contra-directions to pass material to a compartmented wheel from which the material subsequently falls in measured quantities into containers passing beneath the wheel. As applied to a machine for sowing seeds from a device 29, 30, peat moss is fed by a conveyer 3 from the hopper 2 until it falls through a shoot 8 and then between the drums 9, 10, the moss then falling into the compartmented wheel. As the wheel rotates, the material in each compartment is emptied into containers on a moving conveyer 22.
Patent GB-1053156-A (GB)
IPC: C08C1/02
Abstract: 1,053,156. Preserving latex against coagulation. KEPONGS PLANTATIONS Ltd. Sept. 21, 1965 [May 4, 1965], No. 18760/65. Heading C3E. Concentrated rubber latex is prevented from coagulating as a result of freezing by the addition of a non-ionic surface-active agent to the latex prior to exposure of the latex to freezing conditions, the proportion of surface-active agent being sufficient to stabilize the latex against coagulation on freezing but insufficient to protect the latex against coagulation on the addition of an acid.
Patent GB-1053595-A (GB)
IPC: B60P1/38
Abstract: 1,053,595. Discharging vehicles; discharging material from hopper bottoms. GEORGE WHITTAKER & SONS (KNUTSFORD) Ltd., [trading as CRANFORD ENGINEERING CO.]. Aug. 25, 1965 [Sept. 18, 1964], No. 38125/64. Headings B8E and B8S. A bulk unloading body comprises a hopper 11, Fig. 1, the bottom of which is closed by an endless conveyer belt 15 adapted to unload the hopper through an exit port 18 and extending over rollers 16, 17, the roller 16 being driven and a tensioning roller 19 being provided which is vertically adjustable. The hopper is supported on a wheeled chassis 10. The roller 19 is rotatably mounted on an axle 20, Fig. 2 (not shown), carried by arms 21 which are adjusted by screw means 22.
Patent GB-1053793-A (GB)
IPC: C07C205/12
Abstract: 1,053,793. Polychloronitrobenzenes and tetrachloro - o - phenylenediamine. FISONS PEST CONTROL Ltd. Oct. 23, 1963 [Nov. 10, 1962], No. 40957/63. Divided out of 1,053,792. Heading C2C. 1,2,3,4-Tetrachloro-5-nitrobenzene is made by chlorinating 1,2,4-trichloro-5-nitrobenzene by treatment with chlorine in the presence of chlorosulphonic acid and iodine. The chlorination is preferably effected in the temperature range 30-150‹ C., the chlorosulphonic acid being present in amount comprising 0À2 to 4À0 mols., and the iodine 0À15-2% by weight, on the basis of the 1,2,4-trichloro-5-nitrobenzene. The latter may be made by mono-nitration of 1,2,4-trichlorobenzene with nitric acid or with a mixture of nitric acid and sulphuric acid. 1,2,3,4 - tetrachloro - 5,6 - dinitrobenzene may be made by nitration of the 1,2,3,4-tetrachloro- 5-nitrobenzene using mixed nitric and sulphuric acids at elevated temperature, preferably using 80-100% HNO 3  and 90-100% H 2 SO 4 , in the range 50‹ to 115‹ C. Tetrachloro-o-phenylenediamine may be made by reducing 1,2,3,4-tetrachloro-5,6-dinitrobenzene, for example with stannous chloride and hydrochloric acid or an alcohol, with sodium hydrosulphite, or with zinc and an acid.
Patent GB-1084336-A (GB)
IPC: C08K5/38
Abstract: 1,084,336. Stabilizing polyurethanes with disulphides. DUNLOP RUBBER CO. Ltd. June 10, 1964 [July 2, 1963], No. 26121/63. Addition to 976,901. Heading C3R. A polyurethane contains, as an antioxidant, a xanthogen disulphide compound of formula ROCS-SS-SCOR 1  where R and R 1  each represent an alkyl group, an alicyclic group, an aralkyl or aryl group. The antioxidant may be present in amount 0À01- 5% and may be e.g. dimethyl, diisopropyl, diisobutyl or diamyl xanthogen disulphide and may be added at any stage during the preparation of the polyurethane. The polyurethane may be obtained by reacting a polyol, e.g. polyether, with a polyisocyanate or polyisothiocyanate. In the example, hexamethylene diisocyanate was added in two stages to polytetramethylene ether glycol followed by trimethylolpropane, dibutyltin dilaurate and diisopropyl xanthogen disulphide.
Patent GB-1143587-A (GB)
IPC: G02B27/28
Abstract: 1,143,587. Polarizing apparatus. PHILIPS ELECTRONIC & ASSOCIATED INDUSTRIES Ltd. March 28, 1966 [March 31, 1965], No. 13550/66. Heading G2J. A deviation prism, particularly for use in a multi-stage digital light deviation system, comprises two prisms 1<SP>1</SP>, 1<SP>11</SP>, Fig. 1, having an incident face ABCD and interface CDFG, and interface PRTV and emergent face QSTV respectively, the two interfaces being in contact with each other and the incident face being parallel to the emergent face. The edges k, k<SP>1</SP>, forming the intersection between the interface and the incident face or the emergent face respectively, are parallel and the optic axis O of prism 1<SP>1</SP> lies in the plane of the incident face and forms an acute angle γ with edge k, whilst the optic axis O<SP>1</SP> of prism 1<SP>11</SP> lies in the plane of the emergent face and forms an angle y Œ 90 degrees with the edge k<SP>1</SP>. Both prisms 1<SP>1</SP>, 1<SP>11</SP> may be of calcite with y = 45 degrees.
Patent GB-1230512-A (GB)
IPC: B23Q7/14
Filed: 1969-09-17
Abstract: 1,230,512. Machine tool details. BUHR MACHINE TOOL CORP. 17 Sept., 1969, No. 45923/69. Heading B3B. A reciprocating bar 10 for moving work pallets P between machine tools, comprises lengths of overlapped and interlocked portions 15-20, carrying pallet engaging dogs 14, the bar being moved along rods 60, and rollers 62, by an hydraulic piston 53. After engaging and moving a pallet to the machine tool, bar 10 is either moved transversely, or pivoted about its own axis, so as to disengage the dog 14 from the pallet, and then retracted. The ends of the bar portions are connected by screws 34, and located by projections and recesses 46, 39, and 38, 47, and two keys and keyways 50, 48. The bar may be of circular or rectangular cross-section.
Patent GB-1231670-A (GB)
IPC: A47C3/30
Filed: 1969-05-05
Abstract: 1,231,670. Fluid pressure jacks. FICHTEL & SACHS A.G. 5 May, 1969 [7 May, 1968], No. 22702/69. Heading B8J. [Also in Division F2] A pneumatic or hydropneumatic piston-andcylinder spring may be mechanically locked in any relative position of piston and cylinder by operating a device 6 inside the cylinder 1 in the vicinity of the pisron 2 which jams part 7 of the piston against the cylinder wall. As shown, the piston is both mechanically and fluidically locked relative to the cylinder, because of the position of the operating device 6, which both causes clamp pins 10 to press a clamp ring 7 against the wall of the cylinder, and closes the through-piston fluid passages 11. To unlock, an operating bar is pressed in and the device 6 moves down, thus releasing both locks. The piston 2 will then rise owing to the lower surface of the piston having a larger area, or can be pushed further into the cylinder if required, and then relocked by releasing the operating bar 5, the operating device 6 then rising into its locking position because of the excess pressure. In Fig. 2 (not shown), the piston may be mechanically locked only. As the piston-rod is rotated relative to the cylinder, it screws into or out of the piston, thus raising or lowering the operating device relative to the piston. In Fig. 3 (not shown), the piston may be both mechanically and fluidically locked and is provided with slits.
Patent GB-1232292-A (GB)
IPC: C01G49/10
Filed: 1968-09-11
Abstract: 1,232,292. Ferric chloride. BADISCHE ANILIN- & SODA-FABRIK A.G. 11 Sept., 1968 [12 Sept., 1967], No. 43109/68. Heading C1A. Anhydrous ferric chloride is produced by reacting scrap iron with a chlorine gas containing 0À5 to 20% by volume of CO with reference to its Cl 2  content and preferably also an inert gas, e.g. N 2 . The reaction may be carried out at temperatures of more than 700‹ C., preferably 800‹ to 1000‹ C. Oxidic constituents of the iron are also converted to FeCl 3 . The process may be operated continuously.
Patent GB-1238800-A (GB)
IPC: G05B19/404
Filed: 1969-08-04
Abstract: 1,238,800. Automatic control. IKEGAI TEKKO K.K. 4 Aug., 1969 [29 Aug., 1968 (2)], No. 38889/69. Heading B3B. [Also in Division G3] A numerically controlled machine tool is responsive to the output of a tape reader as modified by values derived from a controller storing the output of a measuring element sensing a workpiece dimension with respect to a ring gauge mounted coaxially on a main spindle of the machine tool. As shown, a ring gauge G is secured to a chuck F by a screw H and has two reference surfaces G1, G2. After a preliminary programmed machining operation by tools B1-Bm of a turret C on a cross-slide B a tip of a feeler E of a measuring device D also mounted on the cross-slide B, is brought to engage, in succession, surfaces G1, G2 in response to numerical commands from a controller N, responsive to a tape-reader T. The feeler is then caused to move and engage points W1, W2, W3 on a workpiece W mounted in the chuck. The positional deviation from programmed values of surfaces W1-W3 are derived as described in Specification 1,211,418 and the parallel and axial displacements of a spindle S on which the chuck F is mounted are determined from the positional deviations detected from surfaces G1, G2. The respective positional deviations are memorized as pulses at the positions corresponding to tools B1-B3 in controller N and used in succeeding machining operations to compensate the position of the selected tool. For machining between centres the displacement of the spindle axis, as detected by the engagement of the feeler tip with the ring gauge G, is used to (1) modify the stored deviations corresponding to dimensions W1-W3 in dependence on the axial positions of these dimensions, between centres or, alternatively, (2) rotate the co-ordinate axes of the tool turret.
Patent GB-1239628-A (GB)
IPC: E02D3/068
Filed: 1968-07-18
Abstract: 1,239,628. Tamping machines. VIBROVERKEN A.B. 18 July, 1968 [19 July, 1967], No.34153/68. Heading B4C. [Also in Division E1] A portable machine for tamping earth or a like material comprises a motor unit 1, a compactor unit 2 and a parallel linkage arrangement which connects the motor and compactor units. The arrangement comprises members 10, 11 fixed to the motor unit and compactor unit respectively and pairs of links 8, 9 pivotally connected by resilient means 12-15, e.g. shear stressed rubber elements to the member 10 and compactor unit 2 and the member 11 and the motor unit respectively. Two hand grips are attached to a frame 16 by rubber bushes 19. The motor unit includes a drive motor 4, e.g. a petrol or diesel motor which imparts a reciprocating movement to a connecting rod 5. Alternatively the compactor unit may be driven by a pistoncylinder system.
Patent GB-1251386-A (GB)
IPC: G09F21/02
Filed: 1968-03-29
Abstract: 1,251,386. Mechanical interrupters. JOSEPH LUCAS (INDUSTRIES) Ltd. 21 March, 1969 [29 March, 1968], No. 15175/68. Heading H1N. A contact breaker assembly for use in ignition distributors comprises a plate 10, a fixed contact 12 carried by plate 10, on insulating heel member 13 mounted for pivotal movement relative to plate 10, a movable contact 19 carried by heel member 13 and a spring 21 urging heel member 13 to pivot in a direction to engage movable contact 19 with fixed contact 12. Movable contact 19 is secured to a metal shell 17 engaged with heel member 13, and spring 21 is in the form of a metal strip, one end of spring 21 being engaged in a groove 23 in heel member 13 and being formed adjacent its end with a projection 22 which extends through shell 17 into engagement with the wall of an aperture in heel member 13 and thereby seems to secure spring 21 and shell 17 to heel member 13, the other end of the metal strip being anchored to plate 10. In a second embodiment, Fig. 5 (not shown) the end of spring 21 is bifurcated, the two fingers thus formed projecting into groove 23 and projection 22 is formed integral with spring 21 at the base of the fingers.
Patent GB-1258043-A (GB)
IPC: A62B7/14
Filed: 1967-10-25
Abstract: 1,258,043. Valves. HAWKER SIDDELEY AVIATION Ltd. 27 Jan., 1969 [25 Oct., 1967], No. 48559/67. Heading F2V. [Also in Division F4]  An air supply nozzle mounted on a duct 1 comprises a duct 18 and a body member 5 which are rotatable within a mounting 3, the duct 18 being threadedly movable axially within the member 5 from the position shown in which all the air is delivered through a gap 9 to a position in which all the air flows through holes 11, 15 in the duct 18 and member 5 respectively.
Patent GB-1258102-A (GB)
IPC: C21C5/36
Filed: 1969-03-28
Abstract: 1,258,102. Slag forming agent. NIPPON STEEL CORP. March 28, 1969 [March 30, 1968],  No.16285/69. Heading C7M. A slag-forming agent for use in steel-making comprises lumps of a mixture of CaO, 29-60 wt. per cent, FeO or Fe 2 O 3 , 25-60%, and SiO 2 , 6-30%, said lumps being formed by partially melting particles of said ingredients at 1000-1700‹C. to produce a glassy material covering the boundaries of said particles and bonding them to one another. The agent may also contain less than 25% (aggregate) of Al 2 O 3 , CaF 2 , TiO 2 , MgO, MnO, or alkali metal oxide, e.g. Na 2 O or K 2 O.
Patent GB-1258671-A (GB)
IPC: C10K1/12
Filed: 1969-07-29
Abstract: 1,258,671. Removing H 2 S and CO 2  from gas streams. H. E. BENSON, J. H. FIELD and W. M. EPES. 29 July, 1969, No. 38046/69. Addition to 1,255,201. Heading B1L. CO 2  and/or H 2 S are removed from gas streams, e.g. natural gas or gas from the water gas shift of natural gas, by passing the gas by line 15 to absorber 10 which is operated at superatmospheric pressure. In zone A, the gas flows in countercurrent to scrubbing liquid which enters by line 12, and in zone A' in countercurrent to liquid which enters by line 11, the purified effluent leaving by line 16, condenser 17 and line 19. Rich scrubbing liquid which collects in the sump of absorber 10 passes by line 14 to valve 21 where it is divided into two streams, one passing to the head of regenerator B and the other to the head of regenerator C. Zone B is maintained at a higher temperature and pressure than zone C, but in both zones stripping and regeneration is effected with steam entering zones B and C by lines 39, 35 respectively. This steam is raised by heating stripped scrubbing liquid in sumps 30, 28 by means of hot feed gas which enters by line 40 and passes sequentially through reboilers 36, 32 before passing by lines 44, 15 to absorber 10. Regenerated liquid from sump 30 of zone B passes by line 31 to flash tank 54 where pressure is partly released; steam produced thereby passes to zone C to form part of the stripping steam used therein. The residual regenerated stripping liquid passes by lines 57, 11 to zone A' of absorber 10; less highly regenerated liquid from sump C passes directly by lines 29, 12 to zone A of absorber 10. Stripped acid gas leaves zones B, C by lines 49, 52 and 45, 48 respectively. In other embodiments, (a) condensate from condensers 46, 50 is used to generate steam for zone C in the reboiler associated therewith, and zone A' of absorber 10 is split into two zones, the upper of which is supplied with the same regenerated liquid from zone B as the lower, but at a lower temperature (see Fig. 2, not shown); and (b) where the feed gas is cool, it is passed directly to an additional preheater section at the base of the absorber the rich cool liquid therefrom being heat exchanged with highly regenerated liquid passing to the uppermost zone of the absorber proper (which has three zones), the middle zone being fed with uncooled highly regenerated liquid from zone B and the lower zone with less highly regenerated liquid from zone C (see Fig. 3, not shown). In all these embodiments, flow in the absorber between gas being treated and scrubbing liquid is countercurrent. The scrubbing solution is suitably aqueous potassium carbonate, preferably containing diethanolamine; alkali metal borate, arsenious oxide, or an amino acid such as glycine may however be included.
Patent GB-1264681-A (GB)
IPC: A62D1/00
Filed: 1969-04-18
Abstract: 1,264,681. Fire-protective films for hydrocarbon liquids. MINNESOTA MINING & MFG. CO. 18 April, 1969 [19 April, 1968], No. 20038/69. Heading ASA. An aqueous composition capable on dilution with water of forming a vapour-barrier film on the surface of hydrocarbon liquids to suppress vaporisation therefrom comprises a fluorocarbon surfactant which contains a water-soluble fluoroaliphatic group and a compatible fluorine free film-promoting surfactant which is water-soluble to at least 0.02% by wt. in water at 25‹C, the composition being free from volatile flammable materials. In this context "compatible" means that the two surfactants do not interact to an inactive product. Specified fluorinated surfactants include C 8 F 17 SO 2 N(C 2 H 5 )C 2 H 4 OPO(OH) 2 ; C 8 F 17 SO 2 N(C 2 H 5 )COOK; C 7 F 15 COOH(CH 3 ) 2 NC 3 H 6 NHC 2 H 4 COOH; and several of the type C 7 F 15 CONHC 3 H 6 N(or N<SP>+</SP>)A. Numerous fluorine-free surfactants are specified. A water-soluble electrolyte, e.g. NaCl or MgSO 4  may also be present, e.g. as in sea water. If required, some of the compositions may be foamed per se by admixture with air or vaporised propellant to form extinguishant compositions. Others form stable foams when mixed with an auxiliary foaming agent, e.g. a hydrolysed protein or a perfluoroaliphatic carbonamido betaine, and/or a foam stabiliser, e.g. a polyoxyethylene glycol or butoxy hydroxyethoxy ethane. Glycerol or ethylene glycol anti-freeze may be added. The foamed compositions are compatible with solid extingishants, e.g. KHCO 3 . Film-forming properties of the compositions of the invention are tested on cyclohexane. The compositions can be used on, e.g. toluene, xylene, gasoline, kerosene and fuel oil.
Patent GB-1265459-A (GB)
IPC: A43B23/20
Filed: 1970-11-24
Abstract: 1,265,459. Boots, &c. S. CHELMINSKI. 24 Nov., 1970 [25 Nov., 1969; 2 July, 1970], No. 55928/70. Heading A3B. A wear-resistant and non-skid sole 12 or heel 30 has a plurality of perforated holes 20 or 40 and plurality of polyurethane plugs 28 or 42 which are exposed on the tread surface of the sole of heel. The holes 20 and plugs 28 extend through the tread sole 14 and intermediate sole 16 and the holes 40 and plugs 42 extend through the two lower layers 34, 36 of the heel 30. The plugs 28, 42 may be secured in the holes 20, 40 by (1) inserting pre-formed plugs in the holes (ii) injecting molten thermoplastic polyurethane into the holes and allowing it to cool and harden or (iii) casting a polyurethane forming mixture into the holes and heating to cure the mixture. In each case the holes may be pre-coated with an adhesive primer. The plugs 28 may be cylindrical, as shown, or may be tapered or stepped. The plugs may project beyond the tread surface of the sole or heel. In a modification (not shown) a shoe has a plugged sole and a heel which is not plugged but which has a top lift made entirely of polyurethane.