baber/WOPTO huggingface dataset:
Patent WO-2021194491-A1 (WO)
Title: Peptides immunomodulateurs modifiés de manière covalente avec des petites molécules
Inventor: MASCARENHAS DESMOND
IPC: A61P9/10
Filed: 2020-03-26
Abstract: Cette invention concerne des peptides dérivés de l'IGFBP modifiés, collectivement appelés "peptides immunomodulateurs", et des compositions et des procédés associés. Les modifications chimiques apportées aux peptides à l'aide de petites molécules, et des extensions de séquence à des séquences de noyaux immunomodulateurs présentent de nouvelles activités biologiques surprenantes. L'invention construit la puissance combinatoire de la classe des peptides immunomodulateurs en mettant en évidence les séquences de noyaux qui se lient à un métal ou à des glycosaminoglycanes tels que l'héparine. L'invention divulgue des propriétés biologiques surprenantes de compositions dérivées de ces modifications, comprenant de nombreuses nouvelles utilisations thérapeutiques et diagnostiques (par exemple, la modulation immunitaire de la signalisation TLR, la synthèse améliorée du collagène par les fibroblastes de la peau, et la synergie avec un agoniste de RIG-1 dans la destruction de cellules de mélanome). L'invention concerne également des procédés pour améliorer les utilisations divulguées précédemment des peptides immunomodulateurs en montrant comment les modifications de l'invention peuvent accroître l'efficacité des peptides immunomodulateurs dans un modèle de traumatisme par brûlure.
Patent WO-2020206346-A1 (WO)
Inventor: CZAPLICKI MICHAEL
IPC: C08L63/00
Filed: 2020-04-03
Abstract: The present teachings provide for a two-part system and a method of using the two-part system, the two-part system comprising: a first component including one or more epoxy resins; a second component including one or more phosphate esters; and wherein, upon mixing the first component and second component a cured elastomeric composition is formed in a temperature of about 0 °C to about 50 °C.
Patent WO-2020223611-A1 (WO)
Inventor: HOGUE GRANT D
IPC: A61B17/08
Filed: 2020-05-01
Abstract: Certain embodiments are directed to a scoliosis treatment device, an internal elastic brace (IEB) for scoliosis, and methods of using or deploying the same to treat scoliosis. The scoliosis treatment device includes various components that are assembled and deployed to provide a compressive force to the convex side of an abnormally curved spine by tethering the ribs on the convex side of the spinal curvature.
Patent WO-2020231651-A1 (WO)
Inventor: BUEHLER MICHAEL J
IPC: B60R19/34
Filed: 2020-05-01
Abstract: A crash attenuator includes a frame having a first frame member and a second frame member rigidly connected with a hinge assembly in a pre-impact configuration. The first and second frames are hingedly connected with the hinge assembly in an impact configuration. The hinge assembly includes a release plate fixedly connected to the first frame member, wherein the release plate comprises a fastener opening and a slot extending between the fastener opening and an edge of the release plate, and a fastener extending through the fastener opening and connecting the release plate to the second frame member when the first and second frames are in the pre-impact configuration. A hinge assembly, and method of using the crash attenuator, are also provided.
Patent WO-2021011081-A1 (WO)
Inventor: NGUYEN PHILIP D
IPC: C09K8/62
Filed: 2020-05-22
Abstract: A variety of systems, methods, and compositions are disclosed, including, a method for treating a subterranean formation, the method comprising: injecting a pad fluid into the subterranean formation at a pressure sufficient to create at least one fracture in the subterranean formation; injecting a first treatment fluid into the at least one fracture, wherein the first treatment fluid comprises: an aqueous base fluid, and a first proppant particulate; allowing the first proppant particulate to gravitationally migrate into a portion of the at least one fracture; injecting a second treatment fluid into the at least one fracture, wherein the second treatment fluid comprises: a suspension base fluid comprising a viscosity of about 50 cP to about 10,000 cP, and a second proppant particulate; and allowing the fracture to close, thereby forming a full proppant pack and a partial proppant pack in the at least one fracture.
Patent WO-2020256917-A1 (WO)
Inventor: TALBERT JOSHUA
IPC: A61B1/06
Filed: 2020-06-01
Abstract: Systems, methods, and devices for laser scanning in a light deficient environment. A system includes an emitter for emitting pulses of electromagnetic radiation and an image sensor comprising a pixel array for sensing reflected electromagnetic radiation. The system includes a controller comprising a processor in electrical communication with the image sensor and the emitter, wherein the controller synchronizes timing of the pulses of electromagnetic radiation during a blanking period of the image sensor. The system is such that at least a portion of the pulses of electromagnetic radiation emitted by the emitter comprises a laser scanning pattern.
Patent WO-2020247463-A1 (WO)
Inventor: STEPHAN ERICH KAI
IPC: H01L31/048
Filed: 2020-06-03
Abstract: A multi-rail system for mounting solar modules to a surface, such as a roof, uses two rails to support a first row of solar modules, and a single rail to support each subsequent row of solar modules. Splices connect edges of solar modules between rows, providing support along one edge of the solar modules for the subsequent rows.
Patent WO-2021015947-A1 (WO)
Title: Automated audio-to-text transcription in multi-device teleconferences
Inventor: GORNY THOMAS
IPC: G10L15/26
Filed: 2020-07-08
Abstract: A system and method are disclosed for generating a teleconference space for two or more communication devices using a computer coupled with a database and comprising a processor and memory. The computer generates a teleconference space and transmits requests to join the teleconference space to the two or more communication devices. The computer stores in memory identification information, and audiovisual data associated with one or more users, for each of the two or more communication devices. The computer stores audio transcription data, transmitted to the computer by each of the two or more communication devices and associated with one or more communication device users, in the computer memory. The computer merges the audio transcription data from each of the two or more communication devices into a master audio transcript, and transmits the master audio transcript to each of the two or more communication devices.
Patent WO-2021016254-A1 (WO)
Title: Estrogen receptor-modulating compounds
Inventor: MILLER CHRIS
IPC: C07D487/04
Filed: 2020-07-21
Abstract: Described herein are compounds that are estrogen receptor modulators. Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such estrogen receptor modulators, alone and in combination with other compounds, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.
Patent WO-2021026205-A1 (WO)
Inventor: BANSAL ASHISH
IPC: C07K16/28
Filed: 2020-08-05
Abstract: Methods for treating moderate-to-severe or severe atopic dermatitis in a pediatric subject are provided. In one aspect, the methods comprise administering to the subject one or more doses of an interleukin-4 receptor (IL-4R) antagonist, such as an anti-IL-4R antibody or antigen-binding fragment thereof.
Patent WO-2021034663-A1 (WO)
Title: Method for dynamic categorization through natural language processing
Inventor: ROBERTS GREGORY
IPC: G06F40/00
Filed: 2020-08-14
Abstract: Dynamic categorization of documents from a semi-static classification taxonomy through the use of key terms, concepts, and entities. Dynamic categorization is a method for retrieving documents that are relevant to a specific category, which can be defined at the time the documents are needed. This is in contrast to a priori sorting and tagging (identifying) documents as to what categories they belong. The categories can be defined not just as a set of key words but may also include phrases, entities and/or relationships found in the document(s), complex field queries, weighted queries against words, as well as exclusion conditions.
Patent WO-2021050555-A1 (WO)
Inventor: ZHANG YING
IPC: C07D261/18
Filed: 2020-09-09
Abstract: La présente invention concerne des compositions et des procédés pour le traitement de troubles qui conduisent à l'accumulation d'oxalate, telle que l'hyperoxalurie primaire 1.
Patent WO-2021118663-A1 (WO)
Inventor: KADAKIA PALAK
IPC: B25J9/16
Filed: 2020-09-09
Abstract: A system and method provide an automation solution for guiding a contact center agent during a communication session by providing contextual in-line assistance. Robotic process automation (RPA) is used for automating workflows and processes with robots that capture information from multiple applications of a contact center system and generate contextual guidance for the contact center agent via callout activities during the communication session.
Patent WO-2021091624-A1 (WO)
Title: Method and device for safe percutaneous pericardial drainage
Inventor: DOBRILOVIC NIKOLA
IPC: A61B17/34
Filed: 2020-09-22
Abstract: A safe, reliable, reproducible system and method for entry into the pericardial sac. The method and system described generally includes penetration of the subcutaneous tissue with a guide sheath or a relatively blunt stylet contained within a sheath. The stylet is removed from the sheath and a hook mechanism is installed. Once in contact with the pericardium, the hook is engaged with the pericardial tissue, allowing the hook mechanism to draw the pericardium away from the heart to create a greater space between the heart and pericardium allowing needle insertion onto the pericardial cavity in a much safer and controlled manner.
Patent WO-2021061980-A1 (WO)
Title: Methods for diagnosing and treating uveitis
Inventor: MAHAJAN VINIT
IPC: C12Q1/68
Filed: 2020-09-24
Abstract: Compositions, methods, and kits are provided for diagnosing and treating uveitis. In particular, biomarkers have been identified that can be used to distinguish infectious uveitis from noninfectious uveitis, and further discriminate among bacterial, viral, and fungal uveitis. These biomarkers can be used alone or in combination with one or more additional biomarkers or relevant clinical parameters in prognosis, diagnosis, or monitoring treatment of uveitis.
Patent WO-2021067221-A1 (WO)
Inventor: BANSAL TANYA
IPC: G06N20/20
Filed: 2020-09-29
Abstract: Techniques for automated machine learning (ML) pipeline exploration and deployment are described. An automated ML pipeline generation system allows users to easily construct optimized ML pipelines by providing a dataset, identifying a target column in the dataset, and providing an exploration budget. Multiple candidate ML pipelines can be identified and evaluated through an exploration process, and a best ML pipeline can be provided to the requesting user or deployed for production inference. Users can configure, monitor, and adapt the exploration at multiple points in time throughout.
Patent WO-2021162755-A1 (WO)
Title: Multi-domain chatbot
Inventor: RAMACHANDRAN MUKUND
IPC: H04L12/58
Filed: 2020-10-06
Abstract: A multi-domain chatbot is used to service a message of a user. An automated agent of the multi-domain chatbot may act as an intermediary between the user and a plurality of domain-specific modules of the multi-domain chatbot. The automated agent may receive the message from the user, determine an intent of the message, and based on the intent, determine a group of the domain-specific modules that should be investigated. The automated agent may then investigate the group of domain-specific modules by sending the user message to and receiving responses from the domain-specific modules within the group. Based on the received responses, the automated agent may determine whether to provide, to the user, one of the domain-specific responses or a null response, in the event that none of the domain-specific responses is aligned with the intent of the message.
Patent WO-2021076606-A1 (WO)
Title: Conceptual, contextual, and semantic-based research system and method
Inventor: BEHTASH ALIREZA
IPC: G06F15/18
Filed: 2020-10-14
Abstract: Systems are described in the field of machine learning such as natural language processing for use in researching and searching a corpus of documents in various topical areas such as physical and social sciences. The systems may utilize training, testing, and deployment of models representing a defined space within the corpus. A network of computers and user input devices may be used for receiving research queries via human-computer interface devices and application programming interfaces. Queries may be processed and used as input to the machine learning models. Outputs from the models may include ranking of results reflecting the queries.
Patent WO-2021080924-A1 (WO)
Title: Personal protective equipment fitting device and method
Inventor: GUGINO MICHAEL
IPC: G06K9/00
Filed: 2020-10-19
Abstract: A system and method for performing automated respirator mask fit testing are described. An example embodiment is configured to obtain, with one or more processors, at least one three-dimensional facial image of an individual; convert the facial image to numerical data for analysis, the numerical data representative of facial features, facial dimensions, and/or facial locations on the face of the individual; determine, based on the numerical data, a head form category for the individual; determine, based on the head form category and the numerical data, a face volume for the individual; and generate a mask fit pass (or fail) indication responsive to the face volume satisfying (or not satisfying) face volume fit criteria for the head form category. The principles described herein may also be applied for other personal protective equipment such as industrial head protection, eye and face protection, hand protection, and clothing.
Patent WO-2021091902-A1 (WO)
Title: Combination pharmacological interventions for multiple mechanisms of obstructive sleep apnea
Inventor: MILLER LAWRENCE
IPC: A61K31/433
Filed: 2020-11-03
Abstract: In general, the invention relates to pharmaceutical compositions comprising a norepinephrine reuptake inhibitor (NRI), muscarinic receptor antagonist, and carbonic anhydrase inhibitor and methods of treating Sleep Apnea comprising the administration of these pharmaceutical compositions.
Patent WO-2021097141-A1 (WO)
Title: System and method for implementing design system to provide preview of constraint conflicts
Inventor: WICHARY MARCIN
IPC: G06T11/60
Filed: 2020-11-12
Abstract: A computing system that can operate to implement an interactive graphic design system that enables users to preview and resolve input actions that cause conflict with predefined constraints.
Patent WO-2021102411-A1 (WO)
Inventor: FEINSTEIN GREGORY
IPC: A61K48/00
Filed: 2020-11-23
Abstract: Provided herein are ionizable lipids represented by the Formula (I): or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5, R6, R1, R2, R3, R4, R5,R6, m, and n are as defined herein. Also provided herein are lipid nanoparticle (LNP) compositions comprising an ionizable lipid of the invention and a capsid-free, non-viral vector (e.g., ceDNA). These LNPs can be used to deliver a capsid-free, non-viral DNA vector to a target site of interest (e.g., cell, tissue, organ, and the like).
Patent WO-2021113484-A1 (WO)
Title: Unwrinkling systems and methods
Inventor: BAKER MICHAEL J
IPC: B65H5/36
Filed: 2020-12-03
Abstract: Due to rapid advancement in computing technology of both hardware and software, the labor intensive sewing process has been transformed into a technology-intensive automated process. During an automated process, product materials may become wrinkled or folded, which can slow down the automated process or result in human intervention. Various examples are provided related to the automation of sewing robots, and removal of wrinkles from products. Images of material on a work table can be captured and analyzed to determine if there are wrinkles or folds in the product. The robot can remove the wrinkle or fold by manipulating the material through the use of end effectors such as, e.g., budgers.
Patent WO-2021119513-A1 (WO)
Inventor: CLAUSON LUKE
IPC: A61F9/007
Filed: 2020-12-11
Abstract: A device for delivering a volume of fluid to an eye including a base having a drive mechanism and a disposable fluid cartridge configured to releasably couple to the base to form the device. Related systems, devices, compositions, and methods of use are provided.
Patent WO-2021221730-A1 (WO)
Inventor: CHO ALEX
IPC: B22D11/00
Filed: 2020-12-21
Abstract: A new 7 xxx aluminum alloy provides a unique combination of quantifiable physical characteristics. The alloy may be generally described as a corrosion resistant aluminum-zinc- magnesium based alloy that is copper free or only includes slight amounts of copper as an impurity.
Patent WO-2021138194-A1 (WO)
Title: Pharyngorofacial expander appliance and protocol
Inventor: YOUSEFIAN JOSEPH
IPC: A61C7/10
Filed: 2020-12-23
Abstract: Embodiments of bone anchored expander devices described herein along with the protocol provide improved orthodontic/orthopedic appliances (10) and protocol for expanding or contracting, protracting or retracting, extruding or intruding the upper jaw and dental arch unilaterally or bilaterally in a parallel or a non-parallel way, as well as enlarging the nasal cavity and nasopharyngeal airway. In some embodiments, forces applied are muted by a spring section (20) of force applying arm (18). This expander design and protocol gives the clinician the ability to direct expansion or constriction, protraction or retraction, extrusion or intrusion forces to various segments of the maxillary jaw and arch in parallel or nonparallel configuration minimizing the need for major osteotomies.
Patent WO-2021142003-A1 (WO)
Title: Methods of making monocoques of land vehicles using modular mold systems
Inventor: WILLISON ROBERT
IPC: B62D29/04
Filed: 2021-01-06
Abstract: Land vehicles, modular systems for forming monocoques of land vehicles, and methods of forming monocoques of land vehicles using modular systems are disclosed herein. In certain embodiments, the land vehicles are provided as delivery vehicles and/or utility vehicles. A land vehicle includes a monocoque supporting a plurality of wheels to permit movement of the vehicle relative to an underlying surface in use of the land vehicle.
Patent WO-2021146276-A1 (WO)
Title: Multidirectional apparatus
Inventor: MARECKI ANDREW
IPC: A61B17/00
Filed: 2021-01-13
Abstract: The present disclosure is directed to a multidirectional apparatus that can be attached to a stapler reload apparatus. The multidirectional apparatus can include at least two articulation elements each comprising a cylindrical proximal end, a hemispherical distal end, a central lumen, a wall surrounding the central lumen, and a first pull wire lumen within the wall surrounding the central lumen, wherein the hemispherical distal end of a first articulation element of the at least two articulation elements is nested in the cylindrical proximal end of a second articulation element of the at least two articulation elements and a first pull wire positioned within the first pull wire lumen, and wherein tension applied to the first pull wire causes the second articulation element to move away from a longitudinal axis of the at least two articulation elements in a direction of the first pull wire which is experiencing the tension.
Patent WO-2021154549-A1 (WO)
Title: Accelerator for dense and sparse matrix computations
Inventor: RASHID LAYALI
IPC: G06F9/30
Filed: 2021-01-20
Abstract: A method of increasing computer hardware efficiency of a matrix computation. The method comprises receiving at a computer processing machine, digital signals encoding one or more operations of the matrix computation, each operation including one or more operands. The method further comprises, responsive to determining, by a sparse data check device of the computer processing machine, that an operation of the matrix computation includes all dense operands, forwarding the operation to a dense computation device of the computer processing machine configured to perform the operation of the matrix computation based on the dense operands. The method further comprises, responsive to determining, by the sparse data check device, that an operation of the matrix computation includes one or more sparse operands, forwarding the operation to a sparse computation device configured to perform the operation of the matrix computation.
Patent WO-2021154600-A1 (WO)
Title: Robust spoofing detection system using deep residual neural networks
Inventor: CHEN TIANXIANG
IPC: G10L15/06
Filed: 2021-01-22
Abstract: Embodiments described herein provide for systems and methods for implementing a neural network architecture for spoof detection in audio signals. The neural network architecture contains a layers defining embedding extractors that extract embeddings from input audio signals. Spoofprint embeddings are generated for particular system enrollees to detect attempts to spoof the enrollee's voice. Optionally, voiceprint embeddings are generated for the system enrollees to recognize the enrollee's voice. The voiceprints are extracted using features related to the enrollee's voice. The spoofprints are extracted using features related to features of how the enrollee speaks and other artifacts. The spoofprints facilitate detection of efforts to fool voice biometrics using synthesized speech (e.g., deepfakes) that spoof and emulate the enrollee's voice.
Patent WO-2021167999-A1 (WO)
Title: Device for anti-fog endoscope system
Inventor: CIFELLI DAN
IPC: A61B1/07
Filed: 2021-02-17
Abstract: A device for maintaining an optical path of an optical imaging system free of fog includes an elongated member having a distal end and a proximal end, a near-infrared (NIR) light-absorbing optical window disposed at the distal end, and an optical system disposed along the optical path. The device also includes a coupling module coupled to the elongated member at the proximal end and configured to transmit near-infrared light to the NIR light-absorbing optical window along the optical path and receive a light beam from an area of interest along the optical path.
Patent WO-2021183278-A1 (WO)
Title: Sidecar architecture for stateless proxying to databases
Inventor: MITAL MANAV
IPC: H04L29/06
Filed: 2021-02-22
Abstract: A mechanism for providing connection to a database is described. A connection to the database is intercepted. The connection is assigned to an instance of the database. A sidecar is configured to proxy the connection to the database. The sidecar is stateless and passes all communications for the connection to the instance of the database.
Patent WO-2021188274-A1 (WO)
Title: Automated alert system using unmanned aerial vehicles
Inventor: MCLAUGHLIN Brent
IPC: G08B21/22
Filed: 2021-02-25
Abstract: An automated alert system using unmanned aerial vehicles is described where the system is configured to monitor a selected area via one or more sensors configured to monitor the selected area for an anomaly. A processor in communication with the one or more sensors may be programmed to create or alter a flight path of an unmanned aerial vehicle upon receiving an alert from the one or more sensors for investigating or verifying the anomaly.