baber/WOPTO huggingface dataset:
Patent JP-3404397-B2 (JP)
IPC: C10L1/16
Filed: 1993-12-08
Granted: 2003-05-06
Abstract: Gel-free dispersant additives for lubricating and fuel oil compositions comprise at least one adduct of (A)  alpha -olefin homopolymer or interpolymer of 700 to 10,000 number average molecular weight, free radically grafted with an average of from about 0.5 to about 5 carboxylic acid producing moieties per polymer chain, and (B) at least one non-aromatic nucleophilic post-treating reactant selected from (i) amine compounds containing only a single reactive amino group per molecule, (ii) alcohol compounds containing only a single hydroxy group per molecule, (iii) polyamine compounds containing at least two reactive amino groups per molecule, (iv) polyol compounds containing at least two reactive hydroxy groups per molecule, (v) aminoalcohol compounds containing at least one reactive amino group and at least one reactive hydroxy group per molecule, and (vi) mixtures of (i) to (v); provided that when said post-treating reactant includes one or more of (iii), (iv) or (v), the reaction between (A) and (B) is conducted in the presence of sufficient chain-stopping or end-capping co-reactant (C) to ensure that the grafted and post-reacted product mixture is gel-free.
Patent JP-3694523-B2 (JP)
IPC: C12N15/09
Filed: 1993-03-08
Granted: 2005-09-14
Abstract: A method of altering the receptor binding properties and the stability of neurotrophic factors is set forth. Mutant neurotrophic factors having altered receptor binding specificities are described. Specific embodiments include neurotrophic factors that bind trk receptors but do not bind to the low affinity NGF receptor.
Patent JP-3469234-B2 (JP)
IPC: C12R1/125
Filed: 1991-09-13
Granted: 2003-11-25
Abstract: Lipases comprising a trypsin-like catalytic triad including an active serine located in a predominantly hydrophobic, elongated binding pocket of the lipase molecule, which pocket forms part of and is surrounded by a lipid contact zone, are mutated by deletion or substitution of one or more amino acid residues in the lipid contact zone so as to change the electrostatic charge and/or hydrophobicity of the lipid contact zone or so as to change the surface conformation of the lipid contact zone of the lipases.
Patent JP-3468526-B2 (JP)
IPC: A61P21/00
Filed: 1996-10-25
Granted: 2003-11-17
Abstract: PCT No. PCT/FR96/01674 Sec. 371 Date Sep. 14, 1998 Sec. 102(e) Date Sep. 14, 1998 PCT Filed Oct. 25, 1996 PCT Pub. No. WO97/15304 PCT Pub. Date May 1, 1997The present invention relates to the use of 1-(2-naphth-2-ylethyl)-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine or its addition salts with pharmaceutically acceptable acids for the preparation of drugs intended for the treatment of amyotrophic lateral sclerosis (ALS).
Patent JP-4149511-B2 (JP)
IPC: A61K9/06
Filed: 1994-09-02
Granted: 2008-09-10
Abstract: A stable, effcacious therapeutic cream wherein principal therapeutic compounds are one or more C-20 to C-28 long chain aliphatic alcohols, of which n-docosanol is exeplary, comprising sucrose cocoate, sucrose stearates or sucrose distearate, or mixtures thereof, is disclosed.
Patent JP-4089920-B2 (JP)
IPC: C07K14/31
Filed: 1995-01-16
Granted: 2008-05-28
Abstract: Novel proteins obtainable by mutagenesis of surface-exposed amino acids of domains of natural bacterial receptors, said proteins being obtained without substantial loss of basic structure and stability of said natural bacterial receptors; proteins which have been selected from a protein library embodying a repertoire of said novel proteins; and methods for the manufacture of artificial bacterial receptor structures.
Patent JP-3377212-B2 (JP)
IPC: G01R15/20
Filed: 1995-01-17
Granted: 2003-02-17
Abstract: PCT No. PCT/GB95/00081 Sec. 371 Date Sep. 17, 1996 Sec. 102(e) Date Sep. 17, 1996 PCT Filed Jan. 17, 1995 PCT Pub. No. WO95/20167 PCT Pub. Date Jul. 27, 1995The invention concerns magnetic sensors and, particularly, a magnetic sensor arrangement for use in an electrical measuring device. In the device, magnetic sensors are provided within recesses formed in the arms of the device. The recesses are typically formed within laminations and act so as to shield the magnetic sensors from interference, whilst enabling them to detect a magnetic field of an electrical conductor placed between the two arms.
Patent JP-4091111-B2 (JP)
IPC: A61P31/18
Filed: 1996-03-07
Granted: 2008-05-28
Abstract: Selected amino acid hydroxyethylamino sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease. The present invention relates to such retroviral protease inhibitors and, more particularly, relates to selected novel compounds, composition and method for inhibiting retroviral proteases, such as human immunodeficiency virus (HIV) protease, prophylactically preventing retroviral infection or the spread of a retrovirus, and treatment of a retroviral infection.
Patent JP-4244072-B2 (JP)
IPC: B23B51/00
Filed: 1997-02-17
Granted: 2009-03-25
Abstract: PCT No. PCT/GB97/00437 Sec. 371 Date Aug. 14, 1998 Sec. 102(e) Date Aug. 14, 1998 PCT Filed Feb. 17, 1997 PCT Pub. No. WO97/29877 PCT Pub. Date Aug. 21, 1997A machining tool and method of making same includes a blank that is formed to a shank and which is provided with machining faces. The machining faces are configured to expose material of a PCD or PCBN element that is formed in a recess in the blank and fused to the blank using material from the transition group of elements, such as cobalt. The recess has a configuration that is defined by side walls, a base wall, and end walls, so as to define a mold in which the PCD or PCBN material is formed into an element that becomes fused with the blank. Such fusing is achieved by leaching of the cobalt into the PCD or PCBN element during the application of heat. Thus, no additional fabrication process is required for joining the PCBN or PCD material to the blank.
Patent JP-2988730-B2 (JP)
IPC: A61K8/97
Filed: 1997-02-03
Granted: 1999-12-13
Abstract: Pressurised vessel equipped with a distributor head and containing a transparent monophase composition comprising (A) 0.5-10 wt. % of a propellant gas and (B) 90-99.5 wt. % of an aqueous composition comprising a mixture of surfactants selected from nonionic and amphoteric surfactants, wherein the vessel delivers a foam when the distributor head is activated.
Patent JP-3515130-B2 (JP)
IPC: B65G47/84
Filed: 1998-01-06
Granted: 2004-04-05
Abstract: An automated conveyor sortation and item (20) discharge system (10) for sorting items of varying sizes and weights to designated output destinations along a conveyor. A serpentine configuration is provided by use of a continuous notched conveyor belt (70) layer, which can have no discharge capabilities, or can include. <IMAGE>
Patent JP-3763846-B2 (JP)
IPC: C07K19/00
Filed: 1996-04-26
Granted: 2006-04-05
Abstract: The present invention relates to a fusion polypeptide which comprises a polypeptide having G-CSF activity and a polypeptide having TPO activity and DNA which codes for the fusion polypeptide, to a fusion polypeptide in which a polypeptide having G-CSF activity and a polypeptide having TPO activity are fused via a spacer peptide and DNA which codes for the fusion polypeptide and to a polypeptide in which the fusion polypeptide comprising a polypeptide having G-CSF activity and a polypeptide having TPO activity is chemically modified with a polyalkylene glycol derivative. It also relates to an anemia-treating composition containing the fusion polypeptide as an active ingredient.
Patent JP-4293639-B2 (JP)
IPC: H03H17/02
Filed: 1998-04-28
Granted: 2009-07-08
Abstract: A digital finite impulse response bandpass filter is described. Analog to digital conversion (A/D) of an input signal uses a Sigma-Delta ( SIGMA - DELTA ) converter, resulting in a digital sequence representation of the input signal. A low-pass FIR filter convolves the binary sequence to produce a low-pass vector, and a digital comb filter defined by at least one set of weighted and time-shifted unit impulses convolves the low-pass vector with the comb filter weights. An envelope detector detects a bandpass envelope of the digital FIR bandpass filter. Also described is a filter bank of a plurality of such digital FIR filters arranged in parallel. A square root of a sum of squares of the convolution products of the low-pass vector with the comb filter weights is calculated to estimate the bandpass envelope. The square root of the sum of two squares is estimated by determining the greater of the roots of the two squares and the lesser of the roots of the two squares, calculating a sum of one half the lesser of the roots of the two squares and one half a product of the greater of the roots of the two squares and the square root of three, and selecting whichever is larger between the greater of the roots of the two squares and the sum of one half the lesser of the roots of the two squares and one half the product of the greater of the roots of the two squares and the square root of three.
Patent ES-2394628-B2 (ES)
Title: Sistema de evaluación térmica de prendas ignífugas.
Inventor: YANEZ ALFONSO JORGE
IPC: G01N25/18
Filed: 2010-07-22
Granted: 2014-01-07
Abstract: Sistema de evaluación térmica de prendas ignífugas que comprende:#- un equipo de generación de calor (1) radiante, de convección y de conducción, que comprende un conjunto de barras de carburo de silicio (8), al menos un quemador de gas (9) un brazo con extremo calefactable (10)#- un equipo de obturación (2) por el que atraviesa el flujo de calor producido en el equipo de generación de calor (1),#- un equipo de calibración y medida (3) al que llega el flujo de calor obtenido en el equipo de generación de calor y sobre el que se deposita la muestra a ensayar, que comprende un calorímetro (14) y un dispositivo de medida (15) unidos por una estructura motorizada (13).
Patent ES-2404733-B2 (ES)
Title: Andamiaje híbrido bioactivo, método de fabricación y uso para ingeniería de tejido óseo.
Inventor: MIRANDA GONZALEZ PEDRO
IPC: A61F2/28
Filed: 2011-10-05
Granted: 2013-09-17
Abstract: Andamiaje híbrido bioactivo, método de fabricación y uso para ingeniería de tejido óseo.#La presente invención describe un método de fabricación de un andamiaje híbrido que comprende la obtención de una estructura biocerámica porosa bioactiva utilizando una técnica de conformado libre, y la infiltración de la misma parcial o totalmente con un polímero biodegradable obtenido por polimerización in situ de un monómero precursor del mismo. La invención describe asimismo al andamiaje híbrido obtenido mediante este procedimiento. Además la invención describe un método ex vivo para generar o regenerar un tejido óseo usando el andamiaje híbrido de la invención y uso del andamiaje híbrido, opcionalmente tratado mediante dicho método ex vivo para su uso en un tratamiento de generación o regeneración de tejido óseo.
Patent ES-2516566-B2 (ES)
Title: Procedimiento de espumación-modificación conjunta de betunes para su uso en pavimentación
Inventor: ABAD CUADRI VEGA ANTONIO
IPC: C10M107/00
Filed: 2013-04-29
Granted: 2015-05-20
Abstract: La presente invención se refiere a un procedimiento de obtención de betún espumado, sin adición de agua, empleando yeso o fosfoyeso que liberan el agua de hidratación en presencia de un agente activador. La espumación puede realizarse in situ, mezclando los componentes anteriores en el medio bituminoso a temperatura alta o intermedia. Otro aspecto de la invención se refiere a un procedimiento de recubrimiento de áridos donde el yeso/fosfoyeso se añade conjuntamente con el árido mineral al que se adiciona betún con el agente activador. En ambos casos, el ligante resultante es un betún modificado que presenta un comportamiento mejorado tanto a altas como a bajas temperaturas de servicio.
Patent ES-2640053-B2 (ES)
Title: Carro, máquina y método de impresión digital de planchas de vidrio en su contorno
Inventor: FERNANDEZ VAZQUEZ JUAN JAVIER
IPC: B41J3/407
Filed: 2016-04-29
Granted: 2018-02-15
Abstract: Carro, máquina y método de impresión digital de planchas de vidrio en su contorno.#El carro (2) de la máquina presenta un soporte principal (50) que soporta una serie principal (100) de módulos de impresión (10) y un soporte auxiliar (40) con una serie auxiliar (100') de módulos de impresión. Estando dichas series principal y auxiliar dispuestas perpendicularmente.
Patent AU-2001248588-B2 (AU)
Title: Hybrid glycosylated products and their production and use
Inventor: LEADLAY PETER FRANCIS
IPC: C12N1/21
Filed: 2001-04-17
Granted: 2006-02-02
Abstract: The present invention relates to hybrid glycosylated products, and in particular, to natural products such as polyketides and glycopeptides, and to processes for their preparation. The invention is particularly concerned with recombinant cells in which a cloned microbial glycosyltransferase can be conveniently screened for its ability to generate specific glycosylated derivatives when supplied with polyketide, peptide, or polyketide-peptides as substrates. The invention demonstrates that cloned glycosyltransferases when rapidly screened for their ability to attach a range of activated sugars to a range of exogenously supplied or endogenously generated aglycone templates, show a surprising flexibility towards both aglycone and sugar substrates, and that this process allows the production of glycosylated polyketides in good yield. This overcomes the problem not only of supplying novel sugar attachments to individual polyketides, including polyketides altered by genetic engineering, but also of increasing the diversity of polyketide libraries by combinatorial attachment of sugars.
Patent AU-2001263456-B2 (AU)
Title: Recombinant bacterial phytases and uses thereof
Inventor: BARTON NELSON ROBERT
IPC: A23L29/00
Filed: 2001-05-24
Granted: 2007-02-01
Abstract: A purified and modified phytase enzyme from  Escherichia coli  K12 appA phytase is provided. The enzyme has phytase activity and improved thermal tolerance as compared with the wild-type enzyme. In addition, the enzyme has improved protease stability at low pH. Glycosylation of the modified phytase provided a further improved enzyme having improved thermal tolerance and protease stability. The enzyme can be produced from native or recombinant host cells and can be used to aid in the digestion of phytase where desired. In particular, the phytase of the present invention can be used in foodstuffs to improve the feeding value of phytase rich ingredients.
Patent AU-2001290540-B2 (AU)
Title: Photodynamic therapy light diffuser
Inventor: STEPHENS PATRICK
IPC: A61N5/06
Filed: 2001-08-17
Granted: 2005-07-28
Abstract: A method of obtaining controlled light diffusion from an optical fiber is disclosed. The optical fiber has an abraded section at its distal end that allows transmitted radiation to escape uniformly over the abraded section, forming a generally cylindrical pattern of diffuse light that surrounds the distal end of the optical fiber. <IMAGE>
Patent AU-2002211222-B2 (AU)
Title: Therapeutic use of aerosolized S-nitrosoglutathione in cystic fibrosis
Inventor: GASTON BENJAMIN
IPC: A61K31/7008
Filed: 2001-10-15
Granted: 2006-02-09
Abstract: The present invention is directed to the treatment of cystic fibrosis that involves administration of a nitrosylating agent, such as S-nitrosoglutathione or ethyl nitrite.
Patent AU-2002239315-B2 (AU)
Title: Apparatus and method for filling and sealing valved bags
Inventor: SEARLE DAREN KAY
IPC: B65B51/22
Filed: 2001-11-19
Granted: 2006-11-23
Abstract: A method and apparatus for filling and sealing of containers, such as sealable valved bags are provided. A sealable valved bag is placed in an upright, erect position, with its sealable valve structure presented to the apparatus, in a slightly open position, amenable to receipt of a filling nozzle of a filling tube. A bag sealing apparatus is placed at the same position along a processing path as a filling apparatus. The filling apparatus and the sealing apparatus are both configured for reciprocable movement into and out of engagement with successive ones of the bags, to enable filling, and subsequent sealing of each of such bags, without intermediate indexing of bags from a filling station to a sealing station.
Patent AU-2002318169-B2 (AU)
Title: Modified antibodies to prostate-specific membrane antigen and uses thereof
Inventor: CARR FRANCIS J
IPC: A61P13/08
Filed: 2002-05-30
Granted: 2007-10-18
Abstract: Modified antibodies, or antigen-binding fragments thereof, to the extracellular domain of human prostate specific membrane antigen (PSMA) are provided. The modified anti-PSMA antibodies, or antigen-binding fragments thereof, have been rendered less immunogenic compared to their unmodified counterparts to a given species, e.g., a human. Pharmaceutical compositions including the aforesaid antibodies, nucleic acids, recombinant expression vectors and host cells for making such antibodies and fragments are also disclosed. Methods of using the antibodies of the invention to detect human PSMA, or to ablate or kill a PSMA-expressing cell, e.g., a PSMA-expressing cancer or prostatic cell, either in vitro or in vivo, are also provided.
Patent AU-2002351267-B2 (AU)
Title: Superoxide dismutase mimics for the treatment of ocular disorders and diseases
Inventor: HELLBERG MARK R
IPC: A61K31/555
Filed: 2002-12-06
Granted: 2007-04-05
Abstract: The use of SOD mimics particularly pentaazacycle Mn(II) complex SOD mimics, for the treatment of AMD, DR, and retinal edema is disclosed.
Patent AU-2003222087-B2 (AU)
Title: Novel curcumin analogues and uses thereof
Inventor: WANG HUI-KANG
IPC: C07C49/255
Filed: 2003-03-27
Granted: 2008-08-21
Abstract: The present invention relates to compounds capable of acting as androgen receptor antagonists, pharmaceutical formulations containing the same, and methods of use thereof. Such uses include, but are not limited to, use as antitumor agents, particularly for the treatment of cancers such as colon, skin and prostate cancer and to induce androgen receptor antagonist activity in a subject afflicted with an androgen-related affliction. Examples of androgen-related afflictions include, but are not limited to, baldness, hirsutism, behavioral disorders, acne, and uninhibited spermatogenesis wherein inhibition of spermatogenesis is so desired.
Patent AU-2003231160-B2 (AU)
Title: Salt solution for colon cleansing
Inventor: CLEVELAND MARK VB
IPC: A61K45/06
Filed: 2003-04-28
Granted: 2009-01-22
Abstract: The field of colonic diagnostic and surgical procedures in hampered by the lack of optimal means available to cleanse the colon. A compromise between convenient, distasteful, solid or low volume, hyperosmotic solutions which cause considerable fluid and electrolyte imbalances in patients and large volume, difficult to consume, iso-osmotic solutions has had to be made heretofore. This invention describes a low volume, hyperosmotic solution consisting of sulfate salts with and with out polyethylene glycol. Unlike prior art, this composition is useful for the cleansing of the bowel and, in lower volumes, as a laxative, without producing clinically significant changes in bodily function.
Patent AU-2003244284-B2 (AU)
Title: Electronic directing system
Inventor: PETERSSON ULF
IPC: A01D34/00
Filed: 2003-06-03
Granted: 2008-08-28
Abstract: The invention relates to a method for manoeuvring a self-propelling device (5) towards the middle of a navigational control station, by means of an electronic navigational control system, wherein said self-propelling device (5) comprises: at least one motor, wherein said electronic navigational control system comprises: said navigational control station (3) comprising at least one signal generator (1), at least one conductor loop connected to said at least one signal generator, one sensing unit (14, 15, 16) arranged at the self-propelling device (5), and comprising a receiving unit (14), a control unit (15), a motor control unit (16), said method comprising the following steps: enabling the signal generator to send a current through said at least one conductor loop, said current generating a magnetic field varying in time and space (43, 44, 52, 54), enabling the sensing unit (14, 15, 16) to sense said magnetic field propagating in the air-medium which is transmitted by the at least one conductor loop, enabling the sensing unit (14, 15, 16) to process a signal, enabling the sensing unit (14, 15, 16) to transmit the processed signal to said at least one motor for contributing to the device's (5) movements across a surface, said method further comprising the steps of: causing the sensing unit (14, 15, 16) to manoeuvre the device (5) towards the middle of the navigational control station based on the properties of the sensed magnetic field (43, 44, 52, 54), causing the self-propelling device (5) to move in a course direction that corresponds to that the sensed magnetic field (54) is constant, so that the self-propelling device (5) can be brought into such a position that a charging device at the navigational control station can charge the batteries of the self-propelling device (5), and a corresponding control system.
Patent AU-2003279996-B2 (AU)
Title: Substituted tetralins and indanes and their use
Inventor: MATTHEWS JAY M
IPC: C07C323/44
Filed: 2003-10-17
Granted: 2009-07-09
Abstract: The invention features tetralin and indane compounds, compositions containing them, and methods of using them as PPAR alpha modulators to treat or inhibit the progression of, for example, diabetes.
Patent AU-2003287289-B2 (AU)
Title: Promotion of peroxisomal catalase function in cells
Inventor: TERLECKY STANLEY R
IPC: A61K38/00
Filed: 2003-10-30
Granted: 2009-05-28
Abstract: The molecular mechanisms of peroxisome biogenesis have begun to emerge; in contrast, relatively little is known about how the organelle functions as cells age. The present inventors characterized age-related changes in peroxisomes of human cells and showed that aging compromises peroxisomal targeting signal 1 (PTS1) protein import, with the critical antioxidant enzyme, catalase, especially affected. The number and appearance of peroxisomes are altered in these cells, and the organelles accumulate the PTS1-import receptor, Pex5p, on their membranes. Concomitantly, cells produce increasing amounts of the toxic metabolite, H2O2, and this increased load of reactive oxygen species (ROS) may further reduce peroxisomal protein import and exacerbate the effects of aging. Disclosed are novel compositions and methods for restoring catalase in peroxisomes by use of targeted catalase modified at its C-terminus and/or N-terminus, optionally in combination with polypeptides which promote cellular uptake of proteins, to prevent or overcome the changes that follows aging or that are associated with a number of diseases or disorders.
Patent AU-2004213937-B2 (AU)
Title: Method and module for blocking or unblocking money accounts
Inventor: CANTINI RENATO
IPC: H04W4/50
Filed: 2004-02-20
Granted: 2009-05-21
Abstract: Method for blocking or unblocking of at least one money account that is connected to an identification module (10), whereby the latter is typically a SIM card, intended for identification of a mobile phone (1) within a mobile phone network (3) and the account is for payment of services provided by a supplier (2). The money account can be blocked or unblocked, dependent on the dynamically determined location of the mobile phone. An independent claim is made for a blocking module for blocking financial transactions linked to a mobile phone, based on the location of the mobile phone.