baber/WOPTO huggingface dataset:
Patent CA-2421683-A1 (CA)
Title: Microparticles for delivery of the heterologous nucleic acids
Inventor: BARNETT SUSAN
IPC: A61K47/48
Filed: 2001-09-28
Abstract: Microparticles with adsorbent surfaces, methods of making such microparticles, and uses thereof, are disclosed. The microparticles comprise a polymer, such as a poly(.alpha.-hydroxy acid), a polyhydroxy butyric acid, a polycaprolactone, a polyorthoester, a polyanhydride, and the like, and are formed using cationic, anionic, or nonionic detergents. Also provided are microparticles in the form of submicron emulsions of an oil droplet emulsion having a metabolizable oil and an emulsifying agent. The surface of the microparticles efficiently adsorb polypeptides, such as antigens, and nucleic acids, such as ELVIS vectors and other vector constructs, containing heterologous nucleotide sequences encoding biologically active macromolecules, such as polypeptides, antigens, and adjuvants. Methods of stimulating an immune response, methods of immunizing a host animal against a viral, bacterial, or parasitic infection, and uses of the microparticle compositions for vaccines are also provided.
Patent CA-2422271-A1 (CA)
Inventor: KNIGHTON MARK S
IPC: G06T1/00
Filed: 2001-07-11
Abstract: The three-dimensional imaging system providing distribution over a distribut ed network. A low-cost convenient three-dimensional imaging system having a digitizer and orientation fixture which automatically acquires and calibrate s to each other. Automatic acquisition and calibration provide vastly improved  ease of use. The system interfaces with a distributed network, such that authorization for operation and/or access to data captured may be controlled  at a remote node on the distributed network.
Patent CA-2424643-A1 (CA)
Title: Cd38 modulated chemotaxis
Inventor: PARTIDA-SANCHEZ SANTIAGO
IPC: C12N15/09
Filed: 2001-10-17
Abstract: The present invention relates to methods for modulating the migratory activity of cells expressing CD38 for the treatment of disorders including, but not limited to, inflammation, ischemia, asthma, autoimmune disease, diabetes, arthritis, allergies, infection with pathogenic organisms and transplant rejection. Such cells include, for example, neutrophils, lymphocytes, eosinophils, macrophages and dentritic cells. The invention further relates to drug screening assays designed to identify compounds that modulate the ADP-ribosyl cyclase activity of CD38 and the use of such compounds in the treatment of disorders involving CD38 modulated cell migration. The invention is based on the discovery that CD38 ADP-ribosyl cyclase activity is required for chemotaxis. Furthermore, the invention relates to methods for identifying compounds that modulate the enzyme activity of the S. mansoni CD38 homologue and using those compounds in the treatment of pathologic disorders caused by helminth infection. This is based on the discovery that helminths such as S.  mansoni express CD38 homologues.
Patent CA-2425040-A1 (CA)
Title: Novel rice gene controlling tolerance to salt stress
Inventor: MIYAO AKIO
IPC: C12N15/29
Filed: 2002-08-06
Abstract: It is intended to provide a gene encoding a protein which regulates toleranc e to salt stress. Namely, polynucleotides encoding a plant gene which regulate s the tolerance to salt stress. These polynucleotides involve a polynucleotide  having a nucleotide sequence encoding the amino acid sequence of from methionine at the 1-position to asparagine at the 243-position in SEQ ID NO: 2 in Sequence Listing and a polynucleotide having a nucleotide sequence encodi ng an amino acid sequence derived from the above amino acid sequence by deletio n, substitution and/or addition of one to several amino acids and having a function of regulating the salt stress tolerance.
Patent CA-2425666-A1 (CA)
Inventor: GERLACH MATTHIAS
IPC: A61P29/00
Filed: 2001-10-10
Abstract: L'invention concerne des 3,4-dihydro-pyrido[1,2-a]pyrimidines substituées de formule générale (I), leur procédé de production, des bibliothèques de substances les contenant, des médicaments comportant ces composés, l'utilisation de ces composés pour la préparation de médicaments destinés au traitement de la douleur, de l'incontinence urinaire, des démangeaisons, du tinnitus auriculaire et/ou de la diarrhée, ainsi que des préparations pharmaceutiques contenant ces composés.
Patent CA-2430432-A1 (CA)
Inventor: SUDO SATORU
IPC: H04N7/15
Filed: 2000-12-01
Abstract: L'invention permet d'optimiser les configurations des écrans mère et fille en fonction des types d'images affichées sur ces écrans. On décrit un terminal vidéo capable de présenter un écran fille dans un écran mère, qui comprend une partie de contrôle de signal (15) pour l'optimisation des deux écrans en fonction des types d'images affichées sur ces écrans. Si l'écran mère est un écran composite partagé à plusieurs écrans, la partie de contrôle de signal (15) présente l'écran fille dans un écran de contrôle (11) sur un écran de l'écran composite, et si l'écran mère est l'écran complet, la partie de contrôle de signal (15) présente l'écran fille en format réduit.
Patent CA-2433079-A1 (CA)
Inventor: GREENLAND ANDREW JAMES
IPC: C12N15/82
Filed: 2002-02-13
Abstract: The present invention relates to novel AlcR regulatory elements and nucleic acid sequences coding therefor, and their use in controlling gene expression in organisms such as plants. DNA constructs containing such nucleic acids, in particular, expression cassettes comprising inducible promoter elements and regulatory elements of the invention, which are capable of acting as "gene switches", form further aspects of the invention.
Patent CA-2433600-A1 (CA)
Inventor: ARNOLD BRAD
IPC: H04W72/04
Filed: 2003-06-26
Abstract: There is provided a method for improving an allocation of resources, i.e., frequency and power, to terrestrial services and satellite services that use a same frequency band. The method includes determining a demand (D S) for a resource by users of a satellite system, determining a demand (D T) for the resource by users of a terrestrial system, and allocating the resource between the satellite system and the terrestrial system based on a ratio of D S to D T.
Patent CA-2433909-A1 (CA)
Title: Apparatus and method for reducing papr in an ofdm mobile communication system
Inventor: JIN BYOUNG-IL
IPC: H04J11/00
Filed: 2002-11-09
Abstract: Disclosed is an apparatus and method for reducing a peak-to-average power ratio (PAPR) due to multiple subcarriers in an OFDM (Orthogonal Frequency Division Multiplexing) mobile communication system. In the OFDM mobile communication system, a transmitter pre-emphasizes an output signal of an IFFT  (Inverse Fast Fourier Transform) block, and a receiver de-emphasizes a received signal before FFT (Fast Fourier Transform), thereby efficiently reducing PAPR due to multiple subcarriers.
Patent CA-2437582-A1 (CA)
Inventor: HEINRICH RUSSELL
IPC: A61B17/28
Filed: 2002-02-08
Abstract: An ultrasonic surgical instrument is provided which includes a handle assembly (218), a body (220) extending distally form the handle assembly and an end effector (222) configured to effect cutting, dissection, coagulation and/or ligation of tissue. The end effector (222) includes an ultrasonic member (226). A transducer (32, 132) is supported adjacent, on or within the ultrasonic member (226) and is connected to a power source. Upon actuation of Th. power source, the transducer (32, 132) effects vibration of the ultrasonic member (226). In one preferred embodiment, the end effector (222) is mounted for articulation about the distal end of the instrument.
Patent CA-2446290-A1 (CA)
Title: Fischer-tropsch process
Inventor: SHARP CHRISTOPHER
IPC: C10G2/00
Filed: 2002-05-17
Abstract: A process which comprises contacting a gaseous reactant stream comprising synthesis gas at elevated temperature and pressure with a suspension of a particulate Fischer-Tropsch catalyst comprising cobalt in a liquid medium in a reactor system comprising at least one high shear mixing zone and a reactor vessel wherein the process comprises the steps of: a) contacting the particulate Fischer-Tropsch catalyst with a reducing gas at elevated temperature and pressure outside of the high shear mixing zone(s) and the reactor vessel and subsequently suspending the particulate Fischer-Tropsch catalyst in the liquid medium; b) passing the suspension from step a) throug h the high shear mixing zone(s) where the gaseous reactant stream comprising synthesis gas is mixed with the suspension; c) discharging a mixture comprising the synthesis gas and the suspension from the high shear mixing zone(s) into the reactor vessel; and d) converting the synthesis gas to liqu id hydrocarbons in the reactor vessel to form a product suspension comprising t he particulate Fischer-Tropsch catalyst suspended in the liquid medium and liqu id hydrocarbons.
Patent CA-2446631-A1 (CA)
Title: Anisotropic stochastic screen
Inventor: XU BEILEI
IPC: H04N1/405
Filed: 2003-10-24
Abstract: A system and method for the halftoning of gray scale images by utilizing a pixel-by-pixel comparison of the image against an anisotropic stochastic screen is disclosed. The anisotropic stochastic screen comprises a non-deterministic, non-white noise function which, when thresholded, is designed to produce anisotropic dot patterns having a power spectrum characterized as having negligible low frequency components and a high-frequency region which has an absence of stronger dominant spikes.
Patent CA-2446730-A1 (CA)
Title: Alkyl hydrazide additives for lubricants
Inventor: NALESNIK THEODORE E
IPC: C10M133/16
Filed: 2002-05-03
Abstract: Disclosed herein is a composition comprising: (A) a lubricant, and (B) at least one alkyl hydrazide compound of the formula: formula (I) wherein R1 is a hydrocarbon or functionalized hydrocarbon of from 1 to 30 carbon atoms, R2 a nd R3 are independently selected from the group consisting of hydrocarbon or functionalized hydrocarbons of from 1 to 30 carbon atoms and hydrogen.</SDOA B>
Patent CA-2449972-A1 (CA)
Inventor: PACKER SCOTT M
IPC: B23K20/12
Filed: 2002-06-12
Abstract: A friction stir welding anvil (14) and method of producing a friction stir welding anvil (14) that precludes diffusion or mechanical bonding of the anv il (14) to the work pieces (10A, 10B) are provided. The alternatives for producing such an anvil (14) comprise coating the anvil (14) with diffusion barriers such as oxides, nitrides, intermetallics, and/or refractory metals; manufacturing an anvil (14) either completely or partially from the same; or placing a coating (26) of such materials in the form of a thin sheet or a powder between the anvil (14) and the work pieces (10A, 10B). The anvil (14) disclosed herein exhibits high strength and hardness even at elevated temperatures, such as those greater than 800 ~C, so as to prevent the anvil (14) from mechanically or diffusion bonding to the work pieces (10A, 10B) an d so as to minimize, or eliminate altogether, anvil deformation.
Patent CA-2450163-A1 (CA)
Inventor: SINGH NANKISHORE
IPC: E05F5/08
Filed: 2003-12-04
Abstract: A doorstop having a tapered shape flexible elastomer plastic body, mounted onto a round flat disk shaped tough plastic base. The body is easily locked into position by four T-shaped locking studs. The Plastic base has with one centered hole to accommodate a flat head self-tapping metal screw. The cored out body forms four triangular wedges and a flat disk with four cutouts holes. The flexible body upon impact force of door yields to withstand a cushion and stop to the door. The body will literally bend at the neck with side impact force and return back to its original position and shape without deforming. The doorstop is made with flexible material which will deflect preventing injuries if accidentally hit by feet particularly children who come into contact with stop. The body allows a spring bending effect and instantly returns to its origin al position with minimum or no noise. Body can be removed from base by unlockin g the four T-shaped locking studs.
Patent CA-2450416-A1 (CA)
Inventor: KATAYAMA GOICHI
IPC: F02D41/04
Filed: 2003-11-21
Abstract: An internal combustion engine comprising an engine body. A combustion chamber is formed in the engine body and has at least one valve seat. A valve is configured to move between an open position and a closed position of the valve seat. A valve actuator is configured to actuate the valve. A variable valve timing mechanism is configured to change an actuating timing of the valve actuator at which the valve actuator actuates the valve. At least one sensor configured to sense anal operational condition of the engine. A control device is configured to determine if the engine is operating in a cruising mode. The control device is also configured to reduce engine speed fluctuations during the cruising mode by adjusting the actuating timing of the valve actuator.
Patent CA-2450560-A1 (CA)
Title: Pipe molding system with vacuum and temperature controls of cooling plugs
Inventor: LUPKE MANFRED A A
IPC: B29C48/09
Filed: 2003-11-24
Abstract: A pipe mold produces plastic pipe with an internal wall having a first wall portion and a second wall portion. The pipe mold, includes a cooling plug to assist in setting the pipe wall. The first wall portion of the pipe wall travels over and is in contact with the cooling plug applying heat directly to and providing a first temperature control to prevent access of cooling of the cooling plug. The second wall portion of the internal pipe wall travels over and is spaced outwardly away from the cooling plug. The pipe mold includes a second temperature control which operates in preventing the access of plug cooling as the second wall portion of the internal wall of the pipe travels over the cooling plug.
Patent CA-2451943-A1 (CA)
Inventor: JUBINVILLE LEONARD A
IPC: B68B3/02
Filed: 2003-12-31
Abstract: A single shaft harness device for a horse-drawn vehicle includes a saddle having opposed sides. A ball hitch extends vertically from a saddle. A breast strap is provided to limit rearward movement of the saddle. At least one stabilizer bar is provided having a first end and a second end. The first end of the at least one stabilizer bar is secured to the saddle. In a working position, the stabilizer bar extends substantially horizontally with the second end of the at least one stabilizer bar terminating at a buttocks of the horse. A lower stabilizer bar strap maintains the stabilizer bar in the working position. A rear stabilizer bar strap limits forward movement of the saddle.
Patent CA-2453027-A1 (CA)
Inventor: BEDNAREK MARIA A
IPC: C07K14/68
Filed: 2002-07-08
Abstract: L'invention concerne des peptides cycliques de formule I qui sont des agonistes puissants et sélectifs de récepteurs de mélanocortine-4, et qui, en tant que tels, constituent des outils de recherche utiles pour la détermination des rôles physiologiques du récepteur de MC-4, ainsi que pour les diagnostics, le traitement ou la prévention de troubles ou de maladies dont la médiation est effectuée par le récepteur de MC-4.
Patent CA-2453420-A1 (CA)
Inventor: CLARKE MARK S F
IPC: B82B3/00
Filed: 2002-06-19
Abstract: Methods of aligning single walled carbon nanotube structures into selected orientations for a variety of different applications are achieved by initially dispersing the nanotube structures in aqueous solutions utilizing a suitable dispersal agent. The dispersal agent coats each individual nanotube strzcture in solution. The dispersal agent may be substituted with a suitable functional group that reacts with a corresponding binding site. Dispersed nanotube structures coated with substituted dispersal agents are exposed to a selected array of binding sites such that the nanotubes align with trhe binding sites due to the binding of the substituted functional groups with such binding sites. Alternatively, crystalline nanotube material is formed upon deposition of dispersed nanotube structures within solutions into channels disposed on the surface of the substrate. Combining dispersal agent chemical modification techniques with deposition of the nanotubes into substrate channels is also utilized to produce useful structures.
Patent CA-2454343-A1 (CA)
Inventor: HENDERSON JACK V
IPC: B60K11/04
Filed: 2002-07-18
Abstract: A panel assembly (10) is securable to a front end of a motor vehicle for positioning and securing a plurality of elements thereto. The panel assembly has a core (22) connectable to the front end of a motor vehicle. A skin (24) covers the core (22). A component mounting structure is molded to the skin (24). The component mounting structure is adapted to have the plurality of elements attached thereto in spaced relation. The panel assembly (10) may be assembled to the motor vehicle with the plurality of elements secured thereto.
Patent CA-2454837-A1 (CA)
Inventor: BARBAS-FREDERICKSON SHANA
IPC: C12N15/10
Filed: 2002-04-29
Abstract: A phage genome is engineered to include a novel restriction site at one of two different positions. In a first embodiment, a restriction site is inserted into the phage genome between the end of gene IV and the MOS hairpin which serves as a phage packaging signal for newly synthesized single strands of phage DNA. In a second embodiment, a restriction site is inserted into the phage genome after the MOS hairpin and prior to the minus strand origin. Once the phage genome is modified to contain the new restriction site, the vector can be engineered to be a "88" vector by inserting at the new restriction site a nucleotide sequence encoding at least a functional domain of pVIII and at least a first cloning site for receiving a gene encoding a polypeptide to be displayed and, optionally a second cloning site for receiving to be displayed.  In particularly useful embodiments, the novel vectors are engineered to produce phage particles that display antibodies.
Patent CA-2456743-A1 (CA)
Title: Tocopherol enriched compositions and amelioration of inflammatory symptoms
Inventor: DREON DARLENE M
IPC: A61P31/04
Filed: 2002-08-21
Abstract: The present invention provides non-alpha-tocopherol enriched tocopherol compositions and non-alpha-tocopherol metabolite enriched compositions for u se in the reduction of inflammatory markers associated with inflammation and fo r use in the treatment and/or amelioration of symptoms of inflammation associated with for example, cardiovascular diseases or disorders, infectiou s diseases, diabetes, SIRS, asthma, neurodegenerative disorders, PMS; muscle fatigue or inflammation; and dermal conditions.
Patent CA-2457368-A1 (CA)
Title: A server, system and method for providing access to a public network through an internal network of a multi-system operator
Inventor: SMALL KEITH MACPHERSON
IPC: H04L12/12
Filed: 2004-02-11
Abstract: A network service management server is provided for an internal network operated by a multi-system operator, at a selected location of the internal network, such as a network head-end. The server registers a client connecting to one of the network entities. It also assigns to the client an address associated with the one of the network entities to which the client is connected. The server manages network services by handling information relating to network services for the client based on the assigned address. The server can handle network services for the client based solely on the clients assigned IP address.
Patent CA-2462341-A1 (CA)
Title: Microwave dielectric spectroscopy method and apparatus for assays of proteins and other biological molecules
Inventor: VAN DER WEIDE DANIEL W
IPC: G01N22/00
Filed: 2002-10-11
Abstract: Dielectric spectroscopy is carried out by coupling non~radiated microwave energy from an antenna to a sample to detect changes in the permittivity of the sample within the antenna's near field. The frequency response of the antenna exhibits resonant frequencies in a frequency range of interest.  Changes in the sample as a result of changes in environmental conditions of the sample are exhibited as changes in the antenna's resonant frequency or frequencies. The changes in the positions of the peaks with changes in environmental conditions can be correlated to changes in the condition of the sample, such as unfolding of proteins with increases in temperature of the sample.
Patent CA-2463275-A1 (CA)
Inventor: KOVANKO THOMAS E
IPC: G01R15/20
Filed: 2004-04-05
Abstract: A magneto-striction based, passive optical current sensor is provided that is located at high voltage and communicates to ground level via an optical fiber.  The optical current sensor includes a ferromagnetic core, a modulator of magnetostrictive material, e.g. Terfenol-D in a preferred embodiment, that responds to the magnetic field, and two or more matched fiber Bragg gratings that convert this response into a wavelength modulated optical signal that is transmitted via an optical fiber to ground level electronics. To linearize the output of the optical current sensor, the optical sensor includes arrangements to provide both mechanical and magnetic bias to the modulator.
Patent CA-2466362-A1 (CA)
Inventor: TSOU YU-MIN
IPC: H01M4/88
Filed: 2002-11-07
Abstract: L'invention porte sur un nouveau catalyseur amélioré de sulfure de rhodium utilisé dans la réduction de l'oxygène dans des électrolyseurs industriels et qui est extrêmement résistant à la corrosion et à l'empoisonnement des espèces organiques, ce qui le rend particulièrement approprié pour être utilisé dans l'électrolyse de l'acide chlorhydrique aqueux et également lorsqu'on utilise des contaminants organiques contenant un acide technique. En modifiant ce procédé de préparation, on améliore l'activité et la consistance du catalyseur.
Patent CA-2469040-A1 (CA)
Title: Multi-ply tissue products
Inventor: HU SHENG-HSIN
IPC: B32B29/00
Filed: 2002-09-24
Abstract: In the practice of the invention, a multi-ply paper product or tissue having hardwood layers on the outside and on the inside provides reduced amounts of undesirable sloughing. The multi-ply product includes at least two plies, with three layers in each ply. Hardwood layers, such as for example eucalyptus- containing fiber layers, are provided on the outside surfaces of each ply and also on the interface of one or more plies. The resulting paper product may exhibit reduced sloughing, with little or no sacrifice in softness. A product having two, three, four, or more plies is shown.
Patent CA-2469458-A1 (CA)
Title: Low molecular weight heparin assay, system and reagent therefor
Inventor: MIZE PATRICK D
IPC: B01L3/00
Filed: 2002-12-09
Abstract: A method, kit, system and reagent for measuring low molecular weight heparin in a whole blood sample is provided which involves the use of a Factor Xa activator, such as Russell's Viper Venom, as the coagulation assay initiator .
Patent CA-2469888-A1 (CA)
Inventor: HONG LILY
IPC: A22C29/02
Filed: 2001-12-12
Abstract: La présente invention concerne des procédés de traitement de crustacés morts. Dans un de ces procédés, une étape essentielle du traitement d'un crustacé mort consiste à découper le thorax de ce crustacé. La partie antérieure de ce crustacé est éviscérée par aspiration à travers le thorax découpé. La suppression de ce qui reste du contenu viscéral du crustacé est achevée par la seule étape de rinçage à l'eau de la partie antérieur du crustacé. La partie postérieure du crustacé est éviscérée par aspiration. La suppression de ce qui reste du contenu intestinal de ce crustacé est achevée par la seule étape de rinçage à l'eau de la partie postérieure de ce crustacé. On obtient un crustacé intact possédant une chair de crustacée comestible crue intacte, sur site, cette chair de crustacé comestible crue intacte n'étant pas souillée par les viscères et/ou par la concentration d'impuretés en métaux lourds présentes dans ces viscères.