Patent SG-11201407115X-A (SG)
Title: Carboxylic acid compounds
Inventor: HORI SEIJI
IPC: C07D239/48
Filed: 2013-05-17
Abstract: (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 21 November 2013 (21.11.2013) WIPOIPCT (10) International Publication Number WO 2013/172479 A1 (51) International Patent Classification: C07D 239/48 (2006.01) A61K31/505 (2006.01) A61K31/506 (2006.01) A61P11/00 (2006.01) A61P 31/00 (2006.01) A61P 35/00 (2006.01) A61P 43/00 (2006.01) C07D 239/47 (2006.01) C07D 403/10 (2006.01) C07D 403/12 (2006.01) (21) International Application Number: (22) International Filing Date: (25) Filing Language: (26) Publication Language: PCT/JP2013/064420 17 May 2013 (17.05.2013) English (30) Priority Data: 61/648,816 61/806,158 18 May 2012 (18.05.2012) 28 March 2013 (28.03.2013) English US US (71) Applicants: DAINIPPON SUMITOMO PHARMA CO., LTD. [JP/JP] ; 6-8, Dosho-machi 2-chome, Chuo-ku, Osaka-shi, Osaka, 5418524 (JP). ASTRAZENECA AK- TIEBOLAG [SE/SE]; Sodertalje, SE15185 (SE). (72) Inventors: HORI, Seij i; c/o Dainippon Sumitomo Pharma Co., Ltd., 1-98, Kasugadenaka 3-chome, Konohana-ku, Osaka-shi, Osaka, 5540022 (JP). HASEGAWA, Futoshi; c/o Dainippon Sumitomo Pharma Co., Ltd., 1-98, Kasug­ adenaka 3-chome, Konohana-ku, Osaka-shi, Osaka, 5540022 (JP). URABE, Daisuke; c/o Dainippon Sum­ itomo Pharma Co., Ltd., 1-98, Kasugadenaka 3-chome, Konohana-ku, Osaka-shi, Osaka, 5540022 (JP). KURE- BAYASHI, Hirotaka; c/o Dainippon Sumitomo Pharma Co., Ltd., 1-98, Kasugadenaka 3-chome, Konohana-ku, Osaka-shi, Osaka, 5540022 (JP). (74) Agents: SAMEJIMA, Mutsumi et al.; AOYAMA & PARTNERS, Umeda Hankyu Bldg. Office Tower, 8-1, Kakuda-cho, Kita-ku, Osaka-shi, Osaka, 5300017 (JP). (81) Designated States (unless otherwise indicated, for every kind of national protection available)'. AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available)'. ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG). Declarations under Rule 4.17: — as to the applicant's entitlement to claim the priority of the earlier application (Rule 4.17(iii)) Published: — with international search report (Art. 21(3)) (54) Title: CARBOXYLIC ACID COMPOUNDS o\ l> •t CJ i> (i) i-H o CJ (57) Abstract: The present disclosure concerns at least one entity chosen from compounds of Formula (I) and pharmaceutically ac­ ceptable salts thereof: (I) wherein the variable groups X, Rl, R2, R3 m, n and p are as defined herein. The present disclosure also relates to methods for the preparation of at least one such entity, and intermediates useful in the preparation thereof, to pharmaceut - ical compositions containing at least one such entity, to the use of at least one such entity in the preparation of medicaments, and to the use of at least one such entity in the treatment of conditions such as, for example, allergic diseases, autoimmune diseases, viral diseases, and cancer.