baber/WOPTO huggingface dataset:
Patent BR-PI0815370-B1 (BR)
Title: anticorpos humanos de alta afinidade contra o fator de crescimento neural humano e seu uso, molécula de ácido nucleico, vetor de expressão, método para produção de um anticorpo anti-ngf humano e composiçao farmacêutica
Inventor: JOEL C REINHARDT
IPC: C07K16/22
Filed: 2008-08-08
Abstract: ANTICORPOS HUMANOS DE ALTA AFINIDADE CONTRA O FATOR DE CRESCIMENTO NEURAL HUMANO E SEU USO, MOLÉCULA DE ÁCIDO NUCLEICO, VETOR DE EXPRESSÃO, MÉTODO PARA PRODUÇÃO DE UM ANTICORPO ANTI-NGF HUMANO E COMPOSIÇÃO FARMACÊUTICA. A invenção refere-se a um anticorpo humano ou fragmento de ligação a antígeno de um anticorpo que especificamente se liga ao fator de crescimento neural humano (NGF) com KD de 5 pM ou menos, não reage cruzadamente com a neurotrofina-3 (NT-3), e liga-se a NGF humano com um KD de aproximadamente 2 a aproximadamente 10 vezes superior do que o anticorpo ou fragmento se liga ao NGF de rato e de camundongo. Os anticorpos são úteis no tratamento de dor, incluindo dor inflamatória, dor de incisão pós-operatória, dor neuropática, dor de fratura, dor de fratura osteoporótica, nevralgia pós-herpética, osteoartrite, artrite reumatoide, dor de câncer, dor resultante de queimaduras, dor de gota articular, bem como doenças, tais como carcinoma hepatocelular, câncer de mama e cirrose hepática.
Patent BR-PI0822214-B1 (BR)
Inventor: GERALD ROOS
IPC: H02K23/38
Filed: 2008-11-19
Abstract: The invention relates to a method for producing the rotor winding of an electrical machine having at least four exciter poles in the stator (11) and having a commutator rotor (13) with a number of slots (N) and pole teeth (Z) which deviates from the number of exciter poles, and having a number of individual tooth coils (S) and laminations (L) which is at least twice as high as the number of pole teeth, wherein the individual tooth coils are wound, starting from the first coil (S1) onto in each case that pole tooth with the lowest angular error (Wf) in relation to a pole division (Pt). In order to permit non-critical guidance of the winding wire (17) in the region of the lamination connections, provision is made, at least in the case of a last-wound section (B) of the coils (S), preferably in the case of all of the coils, for the winding wire (17), with which contact is made by a lamination (L) in each case between two coils (S), to be fed from one side of the lamination (L) and guided away from the other side, and for at least one pole tooth (Z), but at most two pole teeth (Z) to be situated between the slot (N) from which the winding wire (17) of the lamination (L) is fed and the slot (N) at which said winding wire is guided away from the lamination (L).
Patent BR-PI1104771-B1 (BR)
Title: método de produção de chapa de aço elétrico com grão orientado
Inventor: YOSHIYUKI USHIGAMI
IPC: C21D8/12
Filed: 2011-09-09
Abstract: método de produção de chapa de aço elétrico com grão orientado. no recozimento de descarburação, a tira de aço laminada a frio é aquecida em uma atmosfera com um grau de oxidação de 0,25 a 1,0 em uma faixa de temperaturas de 750<198>c a 800<198>c a uma taxa média de aquecimento de 2,5<198>c/s ou mais, e a seguir um primeiro tratamento de encharcamento é executado em uma atmosfera com um grau de oxidação de 0,25 a 1,0 em uma faixa de temperatura de 800<198>c a 900<198>c; e a seguir um segundo tratamento de encharcamento é executado em uma atmosfera com um grau de oxidação de 0,03 a 0,25 a uma temperatura de 800<198>c a 900<198>c.
Patent BR-PI1107036-B1 (BR)
Title: conjunto de alvião
Inventor: ADAM OSUSKI
IPC: B02C4/28
Filed: 2011-11-30
Abstract: SUPORTE DE ALVIÃO. Um suporte de alvião para um calibrador de rolo, o calibrador de rolo incluindo pelo menos um tambor de rolo que define um eixo geométrico de tambor, o tambor de rolo rodando em torno de um eixo geométrico de tambor. O suporte de alvião inclui uma base e um rebordo. A base incluir pelo menos um orifício para o recebimento de um prendedor para o acoplamento de forma removível do suporte de alvião ao tambor de rolo. O rebordo é acoplado à base.
Patent EA-000485-B1 (EA)
Title: Hydrotreating process
Inventor: BARRE GUY
IPC: B01J27/051
Filed: 1997-07-29
Abstract: 1. Process for hydrotreating a hydrocarbon distillate fraction in a single stage, which process comprises passing the hydrocarbon distillate fraction downwardly over a stacked bed of two hydrotreating catalysts in the presence of hydrogen, wherein the stacked bed comprises (a) an upper catalyst bed consisting of a hydrotreating catalyst comprising from 0.1 to 15% by weight of at least one noble metal selected from platinum, palladium and iridium, and from 2 to 40% by weight of at least one metal selected from tungsten, chromium, a Group VIIB metal and a metal of the actinium series supported on an acidic refractory oxide carrier, said weight percentages indicating the amount of metal based on the total weight of carrier, and (b) a lower catalyst bed consisting of a hydrotreating catalyst comprising from 1 to 15% by weight of a non-noble Group VIII metal and from 1 to 25% by weight, of a Group VIB metal on an amorphous inorganic refractory oxide carrier, said weight percentages indicating the amount of metal based on the total weight of catalyst, and recovering a liquid hydrocarbon oil product having a reduced content of aromatics and a reduced heteroatom content. 2. Process according to Claim 1, wherein the hydrocarbon distillate fraction has a 10% by weight boiling point of at least 100 degree C and a 90% by weight boiling point of at most 520 degree C. 3. Process according to Claim 1 or 2, wherein the upper bed hydrotreating catalyst comprises palladium and either rhenium or uranium. 4. Process according to any one of Claims 1 to 3, wherein the acidic refractory oxide carrier of the upper bed catalyst comprises a zeolite, alumina, amorphous silica-alumina, fluorinated alumina, phyllosilicate or mixtures of two or more of these. 5. Process according to Claim 4, wherein the refractory oxide carrier comprises modified zeolite Y with alumina as a binder. 6. Process according to any one of the preceding Claims, wherein the lower bed hydrotreating catalyst comprises nickel and/or cobalt as the Group VIII metal and molybdenum and/or tungsten as the Group VIB metal supported on an alumina carrier. 7. Process according to Claim 6, wherein the lower bed catalyst further comprises from 0.1 to 5% by weight of phosphorus.
Patent EA-004924-B1 (EA)
Title: Method for the treatment of infertility in women and use of fsh therefor
Inventor: LOUMAYE ERNEST
IPC: A61K38/24
Filed: 2001-01-09
Abstract: 1. A method for the treatment of infertility in women, comprising administering a patient in need thereof FSH and/or a biologically-active analogue at an initial dose in the range of from 100 to 600 IU followed by a second dose at least 3 days later in the stimulation phase. 2. The method as claimed in claim 1, wherein the FSH and/or a biologically-active analogue thereof is for administration at a dose in the range of from 300 to 600 IU on every third day of the first 6 days of the stimulation phase. 3. The method as claimed in claim 2, wherein the dose is in the range of from 400 to 500 IU. 4. The method as claimed in claim 3, wherein the dose is in the range of from 430 to 470 IU. 5. The method as claimed in claim 3, wherein the dose is about 450 IU. 6. The method as claimed in any one of claims 2 to 5, wherein the medicament is for administration on days 1 and 4, days 2 and 5 or days 3 and 6 of the stimulation phase. 7. The method as claimed in claim 1, wherein the initial dose is in the range of from 100 to 500 IU. 8. The method as claimed in claim 7, wherein the initial dose is in the range of from 200 to 400 IU. 9. The method as claimed in claim 8, wherein the initial dose is about 300 IU. 10. The method as claimed in any one of claims 7 to 9, wherein the second dose is administered between three and six days after the initial dose. 11. The method as claimed in claim 10, wherein the second dose is administered four days after the initial dose. 12. The method as claimed in any one of claims 7 or 8, wherein the second dose is in the range of from 50 to 200 IU. 13. The method as claimed in claim 12, wherein the second dose is in the range of from 70 to 100 IU. 14. The method as claimed in claim 13, wherein the second dose is about 75 IU. 15. The method as claimed in any one of claims 7 to 14, wherein the second dose is repeated daily for 1 to 4 days, preferably 2 days. 16. The method as claimed in any one of claims 7 to 15, wherein the initial dose is administered on day 1, 2, 4 or preferably 3 of the stimulation phase. 17. The method as claimed in any preceding claim, wherein the FSH is recombinant FSH (r-FSH). 18. The method as claimed in any preceding claim, wherein the FSH is human FSH (hFSH).
Patent EA-006767-B1 (EA)
Title: Use of il-18 inhibitors for preparing a medicament for the treatment and/or prevention of heart disease
Inventor: DINARELLO CHARLES
IPC: A61K45/06
Filed: 2002-01-28
Abstract: The invention relates to the use of an inhibitor of IL-18 in the preparation of a medicament for treatment and/or prevention of a heart disease, in particular ischemic heart disease. Combinations of an IL-18 inhibitor and/or a TNF antagonist are also considered for the treatment and/or prevention of a heart disease.
Patent EA-009054-B1 (EA)
Title: An award money payment system for paying out a predetermined award money to a user when the user wins an award in a game using a gaming machine
Inventor: OKADA KAZUO
IPC: G06Q20/00
Filed: 2005-01-21
Abstract: The present invention provides an award money payment system for paying out a predetermined award money to a user when the user wins an award in a game using a gaming machine. The award money payment system includes an award ticket issuing device which prepares and issues an award ticket which is related with identification information of an award winner when the award winner wins an award in a gaming machine; and an award ticket accounting device which reads out information stored in the award ticket and acquires identification of a bearer of the award ticket, and is instructed to perform the accounting of the award money by distributing an award money into the payout of the award money in cash and the transfer of the award money into an account in accordance with a distribution designation input on the condition that the identification of the bearer of the award ticket based on the identification information is established.
Patent EA-007621-B1 (EA)
Title: Process to prepare a particulated metallogene catalyst with a modified aluminoxane and use said catalyst in polymerization of olefins
Inventor: LINDROOS JARMON
IPC: C08F4/649
Filed: 2003-09-04
Abstract: A process for the preparation of an olefin polymerisation catalyst comprising: a) reacting an aluminoxane and a Lewis base in an optionally halogenated hydrocarbon solvent to form a particulate suspension; b) reacting said suspension with a metallocene complex in an optionally halogenated hydrocarbon solvent; and optionally c) isolating the olefin polymerisation catalyst.
Patent EA-009618-B1 (EA)
Title: Preparation for the treatment and prophylaxis of inflammotary skin diseases and muscous membranes
Inventor: BABADJANOVA GALINA ARKADYEVNA
IPC: A61K8/19
Filed: 2002-10-25
Abstract: Application: for skin and mucous membranes inflammatory diseases, ulcers, wounds, burns, tumors at human beings and animals treatment and prophylaxis and besides in cosmetic procedures. Goal: The expansion of medical preparations assortment. The essence of the invention: the preparations wherein the required solutions is recovered at autotrophic iron oxidizing bacteria cultivation, for example, Th. ferrooxidans on corresponding synthetic media or pulps, containing in a form of a solid substrate materials with sulfide minerals or minerals themselves are an active origin. As a result of bacteria growth and development in such media ions of heavy metals and/or metalloids, having toxic effect on pathogenic micro flora are accumulated in the solutions the oxygenation process in the pathological zone, promoting the acceleration of detachment of necrotic masses and damaged tissues reparation is considerably improved.
Patent EA-007367-B1 (EA)
Title: A method for dispensing a beverage and devices therefor
Inventor: RSMUSSEN JAN NORAGER
IPC: B67B7/86
Filed: 2004-05-06
Abstract: A method for dispensing a beverage from a collapsible container (2), in which a collapsible container (2) provided with a base unit (3) is mounted on a substantially flat base part (5) of a dispensing assembly (1) with the outlet (9) of the container facing downwards. A free end of a dispensing tube (10) is arranged at a closed dispensing tap (4) located outside the dispensing assembly (1), and a hollow piercer (11) connected to the dispensing tube is aligned with the outlet (9) of the collapsible container (2). A cover (6) is mounted on the base part (5) in a hermetically sealed manner to form a pressure chamber (8) between the collapsible container (2), the base unit (3), the base part and the cover. An increased pressure is provided in the pressure chamber (8), and the beverage is dispensed after the piercer has pierced the outlet of the container by opening the dispensing tap (4). A beverage dispensing assembly (1) and a container unit with a downwardly facing outlet adapted to such a dispensing assembly is also described.
Patent EA-007557-B1 (EA)
Title: A partition and method for controlling the temperature in an area
Inventor: VAN DIJK JACOBUS JOHANNES WILHELMUS
IPC: F24S10/50
Filed: 2004-07-12
Abstract: Partition for separating the interior of a building construction such as a greenhouse (1) from the surroundings. This partition is fitted at an inclination and is of multi-walled, such as double-walled, construction. According to the invention, the separation wall (5) facing the interior of the building construction is provided with a layer of water (10) with such a small thickness that a free space remains between the wall of the partition facing the outside (4) and the layer of water (10). It has been found that the temperature in the interior of the building (1) construction can be accurately controlled in this way. By means of the choice of the liquid used to build up the layer, it is possible either not to influence the transmission of light or to modify the transmission of light.
Patent EA-009684-B1 (EA)
Title: Rhenium catalyst supported on modified alumina and use thereof in the metathesis reaction of olefins
Inventor: QUERCI CECILA
IPC: B01J21/04
Filed: 2005-03-08
Abstract: A heterogeneous catalyst is described, active in the metathesis reaction of olefins comprising alumina as inert carrier and a rhenium compound as active component, characterized in that rhenium is present in an amount of less than 5% by weight with respect to the total preferably from 1 to 4% by weight, and the inert carrier is impregnated with at least one inorganic halide selected from FeC1, CuC, TiC1, RuC1, ZnC1and NHC1, and/or the corresponding bromides or iodides and, subsequently, treated at a high temperature.
Patent EA-014928-B1 (EA)
Title: Hydraulic metering valve for operation of downhole tools
Inventor: KIMPEL ROBERT P
IPC: E21B34/10
Filed: 2007-06-27
Abstract: Methods and systems for operating a sliding sleeve valve or other downhole well tool (14) that is axially shiftable among a finite number of increments between two extreme configurations such as open and closed configurations. A metering device is described having a pair of piston metering assemblies (36, 38) that operate in parallel fluid flow paths. The first piston metering assembly (36) moves the sleeve of the well tool from a fully closed position to the zero position. The second piston metering assembly can be repeatedly pressurized and depressurized to meter predetermined amounts of fluid from an actuator sequentially to move the sleeve of the sleeve valve in consecutive increments toward a fully open position.
Patent EA-014150-B1 (EA)
Title: Process for casting a magnesium alloy
Inventor: WESTENGEN HAKON
IPC: B22D17/08
Filed: 2007-08-16
Abstract: A process for casting a magnesium alloy consisting of 5 - 1300 % by weight of aluminium, 0.00 - 22.00 % by weight of zinc, also containing 0.10 - 0.5 % by weight of manganese, and the balance being magnesium and unavoidable impurities, the total impurity level being below 0.1 % by weight, wherein the alloy is cast in a die in which the temperature is controlled in the range of 150-340°C, the die is filled in a time which expressed in milliseconds is equal to the product of a number between 2 and 300 multiplied by the average part thickness expressed in millimeter, the static metal pressures being maintained during casting between 20-70 MPa and may subsequently be intensified up to 180 MPa.
Patent EA-017184-B1 (EA)
Title: Contact arrangement and method for assembling a fuel cell stack from at least one contact arrangement
Inventor: REINERT ANDREAS
IPC: H01M8/02
Filed: 2008-01-11
Abstract: The invention relates to a contact arrangement for a fuel cell stack, especially for an SOFC fuel cell stack, comprising an interconnector arrangement (10) which is arranged to establish an electrically conducting connection via at least on contact element (28, 32) on the anode side and at least one such element on the cathode side between an anode (12) of a first membrane electrode assembly (52) and a cathode (16) of a second membrane electrode assembly (52). The invention is characterized in that at least one component to be sintered is provided on only one side of the interconnector arrangement (10), on the side of the interconnector arrangement (10) facing the anode (12) or the one facing the cathode (16), the component being coupled to the first or second membrane electrode assembly (52) in such a manner that the electrically conducting connection can be established via the contact element (28, 32) on the anode side or via that on the cathode side by sintering the component (20) to be sintered. The invention also relates to a method for assembling a fuel cell stack from at least one such contact arrangement. The invention further relates to a fuel cell stack, especially an SOFC fuel cell stack, comprising said contact arrangement, the fuel cell stack preferably being assembled according to the aforementioned method.
Patent EA-017143-B1 (EA)
Title: System and process for production of nitrobenzene
Inventor: HASSAN ABBAS
IPC: B01F27/96
Filed: 2008-06-13
Abstract: A method for producing nitrobenzene is disclosed which comprises forming a dispersion comprising benzene-containing droplets or particles dispersed in a mixture of concentrated nitric acid and concentrated sulfuric acid, wherein said particles have a mean diameter less than one micron, and subjecting the dispersion to reaction conditions comprising a pressure in the range of about 203 kPa (2 atm) to about 6080 kPa (60 atm) and a temperature in the range of about 20 to about 230°C, whereby at least a portion of said benzene is nitrated to form nitrobenzene. A system for carrying out the method is also disclosed.
Patent EA-022755-B1 (EA)
Title: Methods for extended therapy with aminopyridines
Inventor: BLIGHT ANDREW R
IPC: A61K31/52
Filed: 2010-02-11
Abstract: Disclosed herein are methods related to use of aminopyridines, such as 4-aminopyridine, for use in a therapeutically effective manner for patients with a demyelinating condition, such as multiple sclerosis.
Patent EA-023214-B1 (EA)
Title: Device for water-mist sprinkling
Inventor: WILMER DETLEF
IPC: E21C35/23
Filed: 2011-03-25
Abstract: A sprinkling device 1 serves to load cutting heads 2 which are equipped with drilling bits 31-35 for use in mining, tunnelling and civil engineering. The sprinkling device 1 has a plurality of nozzles 21-25 which are arranged next to one another on a sprinkling pipe 3 and from which in each case one spray cone 41-45 emerges which is directed onto the cutting head 2 and comprises a water/air mixture. The centre lines 61-65 of the spray cones which emerge from the nozzles 21-25 are directed onto a position between tangentially onto the basic body 5 of the cutting head 2 and onto the tip 51-55 of the respective drilling bit 31-35.
Patent EA-021664-B1 (EA)
Title: Reflex lens
Inventor: MANVELYAN SVETLANA BAKHSHIEVNA
IPC: G02B17/08
Filed: 2012-12-12
Abstract: The invention relates to optic instrument engineering and can be used as a lens in optoelectronic instruments, for example in night vision devices (NVD). The invention proposes a reflex lens containing the following components in-series installed in the optic axis: the first convergent lens with a reflecting coating in the central zone of the second surface performing a function of a counter-mirror, a negative meniscus facing with its concavity to space of objects and provided on the second surface with a ring-shaped reflecting coating in the peripheral zone performing the function of the main mirror, as well as an aberration compensator including the second convergent and divergent lenses bonded to the first and second surfaces of the negative meniscus respectively. A new feature is that the first convergent lens is made as convex-concave and bonded in the central zone of the second surface to a biconvex lens or as convex-shallow and bonded in the central zone of the second surface to a shallow-convex lens and is located from the aberration compensator at distance of (0.26-0.34) F, and the divergent lens of the aberration compensator is double concave; with that, focal distances of the lens and the aberration compensator meet the following ratio: F=(1.25-1.67) F, where F and F- focal distances of the reflex lens and the aberration compensator respectively. The second convergent lens of the aberration compensator can be made in the form of a double-lens splice. The proposed design of the reflex lens provides reduction of its longitudinal dimensions, improvement of energy use efficiency of an entrance pupil of the lens at maintenance of high quality of an image.
Patent EA-024409-B1 (EA)
Title: Improved process for preparing an intermediate for rilpivirine synthesis
Inventor: GURJAR MUKUND KESHAV
IPC: C07D239/04
Filed: 2012-04-09
Abstract: The present invention relates to the preparation of a key Rilpivirine intermediate, namely (E)-4-(2-cyanoethenyl)-2,6-dimethylphenylamine hydrochloride (II) by a process comprising reaction of the tetrafluoroborate salt of the diazonium ion of 2,6-dimethyl-4-amino-1-carboxybenzyl phenylamine (VI) with acrylonitrile in presence of palladium acetate, followed by treatment with an acid and its subsequent conversion to the hydrochloride salt (II), wherein the undesired Z isomer is less than 0.5% and provides Rilpivirine hydrochloride having Z isomer less than 0.1%.
Patent EA-027867-B1 (EA)
Title: Decelerating device for air conveyed material
Inventor: CRUSON BRIAN
IPC: B65G53/58
Filed: 2012-04-18
Abstract: The decelerating device is designed for deceleration of air-conveyed products (seeds, pellets) placed in a furrow in soil, and is connected in series to a distribution tube in the immediate vicinity of an agricultural air-distribution system. The decelerating device comprises an inlet pipe connected to a distribution pipe for product receiving and air feeding. The inlet pipe is connected to the device central pipe through which excessive air is released upwards through an outlet opening, and the product to be placed into a furrow moves downwards and leaves the device through the outlet opening. A cap is fixed movably on an opening for excessive air release and is adjustable. The inlet pipe is inclined downwards and passes respectively into a screw channel inside the built-in channel in the central pipe to guide the product to the outlet opening.