baber/WOPTO huggingface dataset:
Patent CH-526529-A (CH)
Title: Prepn of steroids glucocorticoidal antiinflammatory
Inventor: PATRICK ANDREW DIASSI
IPC: C12P33/00
Filed: 1969-04-02
Abstract: - Cpds. (XI) are known and have glucocorticoidal-and anti-inflammatory activity. - Acetals and ketals (I) are subjected to 11-hydroxylating micro-organisms to give 11alpha-hydroxy (II) or 11beta-hydroxy cpds. (III).  To obtain (II), microorganisms such as those of the genus Colletotrichum, Tricothecium or Aspergillus are pref. used. - To obtain (III), microorganisms pref. used are of the genus Absidia, Curvularia or Cunninghamella. The microorganisms are cultured aerobically in the customary way using a nutrient medium contng. a nitrogen, carbon and energy source. The latter may be sucrose, molasses etc., a fatty acid, a fat or the steroid itself. Nitrogen sources are e.g. corn steep liquor, distillery extracts or synthetic sources such as ammonium salts, amino acids, urea etc. The culture is aerated submerged and the steroid added during fermentation in a preferred concentration of 0.01-0.1%. Fermentation for 6-96 hrs. and isolation in known manner. The cpds. are then acylated by reacting with acetic anhydride in pyridine to give the 21-acyl derivs. (IV). Reaction with e.g. sulphonyl chloride gives the 9,11-deshydro derivs. (VII).  When using 11alpha-hydroxy cpds. (II) these are first monoacylated to the 21-acyl derivs., followed by reaction with methanesulphonyl chloride to give (VI).  This is treated with glacial acetic acid and sodium acetate to give (VII). Reaction of (VII) with N-bromoacetonide or N-bromosuccinimide in the presence of dioxan and perchloric acid gives (VIII).  Reaction with potassium acetate gives the 9beta,11beta-epoxy derivs. (IX). - These are reacted with hydrofluoric acid to give (X) and hydrolysis in known manner gives (XI).  Cpds. (I) where Y = a double bond may be prepd. from (I) where Y = a single bond by various processes such as reaction with enzymes or dehydrogenating enzymes e.g. Corynebacterium simplex, Nocardia restrictus or Mycobacterium rhodochrous.
Patent CH-505732-A (CH)
Title: Applying labels or plates to blown hollow
Inventor: ERHARD LANGECKER
IPC: B29C49/24
Filed: 1970-05-15
Abstract: Body is blown from tube or strip. A coloured and/or printed element of a thin film of weldable or gluable material is introduced into the blow mould and fixed to the body during blowing. Introduction is either from outside through orifices in the mould wall, or from within via the separation plane of the mould pieces. The element is held by a punch which slides in the mould opening and is curved to correspond to the curvatine of the body. The punch is held during blowing in a withdrawn position relative to the mould wall and is advanced when the element contacts the blow blank in the position corresponding to the finished body; this movement drives out air contained between the element and the blank. The element is curved outwards before its contact with the blank.
Patent DK-116996-A (DK)
Inventor: DAUGAARD KIM
IPC: G06F1/00
Filed: 1996-10-23
Abstract: A method for ensuring that modules (3, 4) to be connected to an apparatus comprising a processor of a specific type, includes providing these modules (3, 4) with a code circuit (6, 7, 13, 21, 24) capable of outputting one or more code words on request. When a module has been connected to the system, the processor of the apparatus reads one or more of the code words from the code circuit (6, 7, 13, 21, 24) of the module, compares the read code word or words with reference code words stored in the apparatus (2), and rejects the module if the read code word or words do not correspond to the reference code words. A large number of different code words are stored in the code circuit (6, 7, 13, 21, 24) of the specific type, and the code circuit is moreover adapted such that a code word can be output correctly only after the lapse of a prefixed period of time, which is considerably longer than a normal output time determined by the implementation of the code circuit, after a previous output of a code word.
Patent DK-183989-A (DK)
Inventor: MONSTREY JOOST
IPC: C08L61/06
Filed: 1989-04-17
Abstract: A phenol foam and a method for preparing substantially closed cell shaped resins on the basis of the condensation product between, on the one hand an either or not substituted phenol and/or phenol derivative and, on the other hand an aldehyde by using a blowing means for forming a hard phenol foam, whereby a physical blowing means comprising chloropropane is used.
Patent DK-189682-A (DK)
Inventor: JONES M
IPC: C07D401/14
Filed: 1982-04-28
Abstract: Compounds of the formula (I) :- 
<CHEM>
 and pharmaceutically acceptable salts thereof and a process for their preparation are disclosed in formula (I).
 W is a 4-imidazolyl group optionally substituted in the 5-position with methyl or bromine; a 2-pyridyl group optionally substituted in the 3-position with C1-4 alkyl, C1-4 alkoxy, halogen, amino or hydroxy; a 2-thiazolyl group; a 2-guanidino-4-thiazolyl group; a 2-furanyl or 2-thienyl group optionally substituted in the 5-position with a group R<1>R<2>N(CH2)m- (where R<1> and R<2> which are the same or different are C1-4 alkyl or together with the nitrogen atom represent a piperidyl, pyrrolidyl or morpholinyl group, and m is an integer from 1 to 4); or a phenyl group substituted in the 3- or 4-position with a group R<1>R<2>N(CH2)m;
 X is methylene (CH2) or sulphur, and
 Y is methylene or, provided X is methylene and W is a substituted phenyl group, oxygen;
 R<3> is a carboxy or hydroxy group; R<4> is hydrogen or a C1-4 alkyl group;
 R<5> is hydrogen, a C1-4 alkyl group, a benzyl group or with R<4> a C3-5 alkylene group; and
 R<6> is hydrogen or a C1-4 alkyl group. The compounds of the invention are histamine H2-antagonists.
Patent DK-245086-A (DK)
Inventor: SCHULZE HERMANN
IPC: F16C27/06
Filed: 1986-05-26
Abstract: 1. A plain bearing of ceramic material for use with pump shafts, in the case of which a bearing bushing (6) rotating with the shaft (5) runs within a bearing (1) made of the same material and the bearing is secured within a housing (9) elastically and more especially silicon carbide is used as the bearing material, characterized in that at its outer periphery the bearing (1) is provided with one or more individual grooves (2 and 3) which are not connected together and have a round cross section, in that the individual grooves extend and/or end at a distance from the end face (4) of the bearing, in that the bearing (1) is externally covered with a hose-like rubber element (7) and in that projections (8) arranged on the inner side of the same snap into the individual grooves (2 and 3) to keep it in place.
Patent DK-257888-A (DK)
Inventor: SCHAECNTER FRIEDRICH
IPC: F23Q2/16
Filed: 1988-05-10
Abstract: A fuel burning lighter, optionally having an adjustable flame height, comprising a supply of liquified gaseous fuel burner means communicating with the fuel supply, valve means positioned between the fuel supply and the burner means, means to provide first force to retain the valve means in a closed position to prevent gaseous fuel from passing therethrough, and means to provide second force less than the first force biasing the valve means toward an open position. The second force providing means normally provides sufficient force to move the valve means to an open position when the first force is relieved or released from acting upon the valve means.
Patent DK-275483-A (DK)
Inventor: RICHARDSON KENNETH
IPC: C07D249/08
Filed: 1983-06-15
Abstract: Triazole antifungal agents of the formula:- 
<CHEM>
 and their O-esters and O-ethers;
 where R is naphthyl, biphenylyl or phenyl optionally substituted by 1 to 3 substituents each independently selected from halo, CF3, C1-C4 alkyl and C1-C4 alkoxy; and R<1> is
 -@NR<2>R<3>

 or -@R<3>

 where X is O or S;
 R<2> is hydrogen of C1-C4 alkyl; and
 R<3> is hydrogen, C1-C4 alkyl, C3-C6 cycloalkyl, aryl, aralkyl, or heteroaryl; or
 R<2> and R<3> taken together with the N atom to which they are attached represent a 1-pyrrolidinyl or piperidino group; and their pharmaceutically acceptable salts. The compounds are useful as human veterinary and agricultural fungicides.
Patent DK-442782-A (DK)
Inventor: ARCHIBALD JOHN LEHEUP
IPC: C07D455/06
Filed: 1982-10-05
Abstract: The invention concerns N-methyl-N-(1,3,4,6,7,11b alpha -hexahydro-2H-benzo[a]quinolizin-2 beta -yl)-iso-butanesulp honamide and the pharmaceutically acceptable acid addition salts thereof. The compounds possess high  alpha 2-adrenoceptor antagonistic activity with a good  alpha 2/ alpha 1 adrenoceptor antagonistic selectivity.
Patent DK-466286-A (DK)
Inventor: HOEFT PETER
IPC: B65D17/34
Filed: 1986-09-30
Abstract: There is provided a tin lid for use with cans of oblong shape in Hansa format, which includes in its lid image section a tear-open portion defined by a self-contained recessed line capable of being broken up at one end of the lid by means of a pull-open ring attached to this end. At the other end, said recessed line includes a straight recessed line portion which extends in chordal-type fashion with respect to the core wall shaped like an arc of a circle and which is positioned perpendicular and symmetrically to the longitudinal lid center line and is further connected with the other recessed line components through an also chordal-type or polygonal recessed line connecting portion. This tear-open portion area defined by the polygonal arrangement of the recessed line, above all, is stiffened by a group of like and completely uniformly distributed beads, which are further associated with the chordal-type recessed line portion in predetermined manner, to so ensure the tear-open portion's final separation from the remaining lid section virtually without any remarkable capacity of the lid image section to undergo spring movement itself.
Patent DK-630686-A (DK)
Inventor: CAVALLERI BRUNO
IPC: C07D513/18
Filed: 1986-12-29
Abstract: The present invention concerns new 2'-substituted-4-deoxy-thiazolo[5,4-c]rifamycin SV derivatives having antibacterial activity.These compounds are obtained by chemical modification of thiazolo[5,4-c]rifamycin SV.
Patent FI-862422-A (FI)
Inventor: PINZA MARIO
IPC: C07D233/32
Filed: 1986-06-06
Abstract: Compounds of Structure (1): 
<CHEM>
 in which
 R<1> is H, C1-5 alkyl (straight or branched), or phenyl;
 W is a bond, -NHC.HR<6>CO- or -NHCHR<6>CONH-CHR<7>CO-, where R<6> and R<7>, which can be the same or different are H or C1-5 alkyl (straight or branched);
 R<2> is H, C1-5 alkyl (straight or branched), aryl or a benzyl group optionally substituted by C1-5 alkyl (straight or branched), C1-4 akoxy (straight or branched) or hydroxy;
 R<3> and R<4>, which can be the same or different, are H, C1-5 alkyl (straight or branched) or phenyl, or R<3> and R<4> can together form a 1,4-butylene or 1,5-pentylene group;
 R<5> is H or -CHR<8>CONR<9>R<1><0>, where R<8>, R<9> and R<1><0>, which can be the same or different, are H or C1-5 alkyl (straight or branched);
 R<1><1> and R<1><2>, which can be the same or different, are H, C1-5 alkyl (straight or branched), or acyl or together with the nitrogen atom shown form a 2-oxo-pyrrolidino group optionally substituted in the 4-position by a hydroxy or C1-5 (straight or branched) alkoxy group, or a 5-oxo-1-imidazolidine group optionally substituted at the 2- position by one or two C1-5 alkyl groups or a 1,4-butylene or 1,5-pentylene group, or optionally substituted at the 4-position by C1-5 alkyl,
 or a pharmaceutically acceptable salt thereof, processes and intermediates for making them, pharmaceutical compositions containing them and their use as nootropic agents.
Patent FI-871356-A (FI)
Inventor: FORSBERG JOHN WESLEY
IPC: C08G65/48
Filed: 1987-03-27
Abstract: A composition is disclosed which comprises a water-dispersible reaction product of (A) at least one compound represented by the formula  <IMAGE>  wherein R is a hydrocarbyl group of from about 8 to about 40 carbon atoms, with (B) at least one water-dispersible amine terminated poly(oxyalkylene). Aqueous concentrates and water-based functional fluids comprising these compositions are also disclosed. These reaction products are useful as shear-stable thickeners for such functional fluids.
Patent FI-872526-A (FI)
Inventor: ARATHOON WILLIAM R
IPC: C12N9/48
Filed: 1987-06-05
Abstract: Biologically active human tissue-type plasminogen activator is produced in a host cell culture by removing from the medium of the culture all medium components which are detrimental to recovery and activity of the plasminogen activator. For example, cross filtration may be used to carry out medium exchange during culture, or the detrimental components may be removed prior to culturing. The cells retain their expression capability after exclusion of the harmful substances so that production of active plasminogen activator can be effected.
Patent FI-874168-A (FI)
Inventor: WILSON GARY LINDSAY
IPC: B27L5/02
Filed: 1987-09-23
Abstract: A veneer lathe (10) having a fixed roller (20), a slidably positionable pressure roller (30) and a slidably positionable following roller (28). A following roller (28) positioning means selectably positions the following roller with respect to the fixed and pressure rollers in response to a following roller position control signal. The rollers are rotated against a block (26) positioned between the rollers, thereby rotating the block with respect to a knife (44), which peels veneer from the block. The pressure roller (30) is slidably positionable in a first plane, and the following roller (28) is slidably positionable into a selected location in a second plane, thereby affording precise control over peeling of the block. A knife positioning means controllably advances the knife into the rotating block in response to a knife position control signal. A knife angling means controllably positions the knife at a selectably variable angle with respect to the rotating block (26) in response to a knife angle control signal.
Patent FI-881331-A (FI)
Inventor: LIEBE-HERZING FRITZ
IPC: B65H5/24
Filed: 1988-03-21
Abstract: Device for separating overlapping and essentially leaf-shapped items moving in a flow on a belt conveyer (1), at the end of which is connected another belt conveyor (5) moving in the same direction and whose transport surface is located below that of the first conveyer. A counting sensor (6) arranged in the region of the step formed by the two conveyors senses the products to be separated and a catch arrangement (7, 8) associated with the lower conveyer and movable in the direction of transport of the latter can be brought into contact with the rear edge of the last item counted, after counting of a predetermined number of items to be separated. Associated with the return drum (3) of the upper conveyer (1) is a conveyor system which exerts a counter-pressure (9) on the items (2) moving on that drum, said system comprising an endless, elastically deformable pressure belt, guided on two return drums (10, 11) and pressing on the items. The forward return drum (10) of said belt is located at a horizontal distance upstream of the return drum (3) of the belt conveyer (1), essentially at the same height as said drum (3), and is preloaded in an adjustable and/or elastic manner against the region of the step formed by the two conveyors (1, 5).
Patent FI-891245-A (FI)
Inventor: MAZUR ROBERT H
IPC: A23L27/30
Filed: 1989-03-16
Abstract: Substituted guanidines containing a tetrazole moiety are provided as high potency sweetening agents.
Patent FI-912677-A (FI)
Inventor: HUIMASALO EINO JOHANNES
IPC: E03C/
Filed: 1991-06-04
Abstract: The subject matter of the invention is a method for the installation of service water and/or heating pipes in a building, in which the mains pipes for incoming water and return water 15 are coupled by way of shut-off valves to distribution parts 12, 13, which are in turn connected by means of plastic pressurised water pipes 19, 21 to the service points using protective pipes 20, 22. Before preparing the floor, for example before pouring concrete, the plastic mains pipes for incoming water and return water are led by means of protective pipes 16 to each apartment on the first floor below the floor level, and a prefabricated coupling and distribution unit 1, 2, 23 moulded into a casing 6 and intended for embedding in the floor is installed for each apartment. T-joints 9, shut- off valves 10 and branch pieces 12 are fixed and permanently coupled to the said unit to form a finished unit, which with T-joints 9 is coupled to the main water pipes 15, and these are led, as required, to the casing 6. After installation of distribution units 1, 2, 23 for the apartment, the said pressured water pipes 19, 21 are installed between the distribution unit and the service points. In this method the protective pipes 16, 19, 21 are taken some distance, preferably 20 mm, into the casing 6. <IMAGE>
Patent FI-914569-A (FI)
Inventor: STAUBER HANS-ULRICH
IPC: B65H29/51
Filed: 1991-09-27
Abstract: The winding apparatus comprises an elevationally adjustable bearing arrangement for rotatably mounting and driving a winding core. Underneath the bearing arrangement, there is provided a conveyor-belt arrangement which is driven by partially training or wrapping around the winding core or, as the case may be, a product package wound up thereon. The conveyor-belt arrangement conveys printed products, which are to be wound up, to the winding core. Prior to winding up the printed products, a winding band is unwound from the winding core and wound onto a winding-band spool. For this purpose, the winding-band spool is connected by means of a slip friction coupling with respective rolls and thus with the conveyor-belt arrangement. During the winding-up of the winding band in conjunction with the printed products onto the winding core, the winding-band spool is braked. A detaching roller for detaching the free end of the winding band wound-up on the winding core as a winding-band supply is drivably coupled with the winding-band spool by means of an endless belt. The endless belt takes the free end of the winding band from the detaching roller to the winding-band spool.
Patent FI-921681-A (FI)
Inventor: KAWAMOTO ISAO C O SANKYO COMPA
IPC: C07D477/00
Filed: 1992-04-14
Abstract: The invention relates to a process for preparing 2 (heterocyclylthio)carbapenem derivatives which can be used as medicaments and which are of the formula (I): <IMAGE> in which: Ra is a group of the formula I-8a or I-9a: <IMAGE> and in which: R1 is a methyl group R3 is a hydrogen atom or a C1-C4-alkyl group, -COOR5 is a carboxyl group or a protected carboxyl group, and the compound of the formula (I) also contains an anion; l is zero or an integer from 1 to 3; p is the integer 1 or 2; or to a pharmaceutically acceptable salt or ester thereof.
Patent FI-924651-A (FI)
Inventor: SEDELMEIER GOTTFRIED
IPC: C07C43/23
Filed: 1992-10-14
Abstract: Compounds of the formula I 
<IMAGE>
 in which R4 is lower alkyl and R1 is either hydroxyl, halogen, a group of the formula -P(=O)(R5)R6 (Ia), a group of the formula -P<+)<R7)(R8)R9X <-> (Ib) or a group of the formula -Si(R7)(R8)R9 (Ic), M is methylene, R2 is hydrogen or a group of the formula 
<IMAGE>
 and R3 is hydrogen or halogen or R1 is hydroxyl or lower alkoxy, M is carbonyl, R2 is hydrogen and R3 is halogen, R5 and R6 in each case independently of one another represent lower alkyl, lower alkoxy, N,N-di-lower alkylamino or benzyl, benzyloxy, phenyl or phenoxy, each of which is unsubstituted or mono- or disubstituted on the phenyl ring, it being possible for the substituents of the phenyl ring in each case to be selected from the group which consists of lower alkyl, lower alkoxy, nitro and halogen, R7, R8 and R9 in each case independently of one another represent lower alkyl, unsubstituted or mono- or disubstituted phenyl, it being possible for the substituents of the phenyl ring in each case to be selected from the group which consists of lower alkyl, lower alkoxy, nitro and halogen, or represent furyl, X<-> is the anion of a hydrohalic acid, a lower alkane-sulphonic acid, a halo-lower alkanesulphonic acid or a benzenesulphonic acid which is unsubstituted or monosubstituted by lower alkyl or halogen and in which Y either represents a direct bond and R10 is lower alkyl, allyl, cyano, lower alkanesulphonyl, halo-lower alkanesulphonyl, benzyl which is unsubstituted or mono- or disubstituted on the phenyl ring, it being possible for the substituents of the phenyl ring to be selected from the group which consists of lower alkyl, lower alkoxy, nitro and halogen, or is benzenesulphonyl which is unsubstituted or monosubstituted by lower alkyl or halogen, or in which Y is a group of the formula -(C=O)- (Ie) or a group of the formula -(C=S)- (If) and R10 is halogen, lower alkyl, halo-lower alkyl, lower alkoxy, lower alkenyloxy, phenyl-lower alkenyloxy, halo-lower alkoxy, lower alkylthio or phenyl, phenoxy, phenylthio, benzyl, benzyloxy or benzylthio, each of which is unsubstituted or mono-or disubstituted on the phenyl ring, it being possible for the substituents of the phenyl ring in each case to be selected from the group which consists of lower alkyl, lower alkoxy, nitro and halogen, with the proviso that in a compound I in which R1 is a group Ib in which R7, R8 and R9 in each case denote unsubstituted phenyl and X<-> is the bromide ion, M is methylene, R2 is hydrogen and R4 is methyl, R3 is other than hydrogen, and with the further proviso that in a compound I in which R1 is hydroxyl, M is methylene, R2 is hydrogen and R4 is methyl or ethyl, and R3 is other than hydrogen, can be used for the preparation of compounds of the formula 
<IMAGE>
 in which R3 is halogen and R4 is lower alkyl and R10 and Y have the abovementioned meanings, and their salts. They are prepared by methods known per se.
Patent FI-925285-A (FI)
Inventor: SEABERG LEONARD JOSEPH
IPC: C12Q1/68
Filed: 1992-11-20
Abstract: An element has been prepared which is useful for the detection of nucleic acids in various formats. The element has a sealable support on which is disposed a nucleic acid reagent composition. The composition is a mixture of a nucleic acid reagent composed of polymeric particles to which an oligonucleotide is covalently attached. The particles are prepared from a first polymer having a glass transition temperature of at least 70  DEG C and have an average diameter of from 0.1 to 3 micrometers. The reagent is adhered to the support using a water insoluble adhesive comprising a second polymer which has a glass transition temperature which is at least 30 DEG C less than the glass transition temperature of the first plymer. The adhesive is present in the composition at from 1 to 20 weight percent. This element provides high sensitivity and low background in hybridization and other nucleic acid assays.
Patent FI-925574-A (FI)
Inventor: BONNEAU LIONEL
IPC: C01F17/00
Filed: 1992-12-08
Abstract: The invention relates to compositions based on ceric oxide, whose specific surface has been stabilised by addition of silicon. These compositions have, after calcination at 800 DEG C for 6 hours, a specific surface of at least 40 m<2>/g and, after calcination at 1000 DEG C for 6 hours, a specific surface of at least 20 m<2>/g. Their silicon content is preferably less than 1 % by weight. They have a remarkably low crystallite size, even at high temperatures. They are obtained according to one of the processes consisting in autoclaving a cerium hydroxynitrate suspension in basic medium and in the presence of a silicon compound, in recovering the product obtained and in then calcining it. The compositions can be used as catalysts and/or as catalyst supports.