Patent SG-11201804100U-A (SG)
Title: Pharmaceutical composition comprising a potent inhibitor of urat1
Inventor: REILAND WAKEMAN JOANNE
IPC: A61K9/14
Filed: 2016-12-07
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau 111111111M 1111111111111111111111111111111111111111111111111111111111111R111111111111111 (43) International Publication Date 15 June 2017 (15.06.2017) (10) International Publication Number WO 2017/097845 Al WIPO I PCT (51) International Patent Classification: A61K 9/14 (2006.01) (21) International Application Number: PCT/EP2016/080111 (22) International Filing Date: 7 December 2016 (07.12.2016) English English (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Declarations under Rule 4.17: — of inventorship (Rule 4.17(iv)) Published: with international search report (Art 21(3)) (25) Filing Language: (26) Publication Language: (30) Priority Data: 62/264,792 8 December 2015 (08.12.2015) US (71) Applicants: ARDEA BIOSCIENCES, INC. [US/US]; 9390 Towne Centre Drive, San Diego, California 92121 (US). ASTRAZENECA AB [SE/SE]; S-151 85 Sodertalje (SE). (72) Inventors: REILAND WAKEMAN, Joanne; 10952 Riesling Drive, San Diego, California 92131 (US). ROWLINGS, Colin; 5484 Shannon Ridge Lane, San Diego, California 92130 (US). LIU, Sha; 5827 Lopez Canyon Way, San Diego, California 92126 (US). BURKE, Gerry; 4427 Corte Morea, San Diego, California 92129 (US). VON CORSWANT, Christian; AstraZeneca R&D, 431 83 Molndal (SE). TANNERGREN, Christer; As- traZeneca R&D, 431 83 Molndal (SE). HJARTSTAM, Johan; AstraZeneca R&D, 431 83 Molndal (SE). (74) Agents: MATHARU, Balvinder Singh et al.; HGF Lim- ited, 4th Floor, Merchant Exchange, 17-19 Whitworth Street West, Manchester M1 5WG (GB). W O 20 17 /097 8 45 Al (54) Title: PHARMACEUTICAL COMPOSITION COMPRISING A POTENT INHIBITOR OF URAT1 (57) : The present invention relates to pharmaceutical compositions containing 2-((3-(4- cyanonaphthalen- 1 -yl)pyridine-4- yl)thio)-2-methylpropanoic acid or a pharmaceutically acceptable salt (hereinafter referred to as the \"Agent\"), more particularly to orally deliverable compositions containing the Agent; to the use of said compositions as a medicament; and to processes for the pre- paration of said compositions.