baber/WOPTO huggingface dataset:
Patent CO-6321244-A2 (CO)
Title: Pirrolopiridinas como inhibidores de cinasa
Inventor: LE HUEROU YVAN
IPC: C07D471/04
Filed: 2010-11-30
Abstract: 1.- Un compuesto seleccionado de la Fórmula Iy estereoisómeros, tautómeros y sales farmacéuticamente aceptables de ellos, en donde:A se selecciona de un enlace directo o CRaRb;R1 se selecciona de hidrógeno, halógeno, CN, alquilo de C1-C6, alquenilo de C1-C6, -O (alquilo de C1-C6), -S(alquilo de C1-C6), cicloalquilo de C3-C6, un heterocíclico de 4 a 6 miembros, fenilo, y un heteroarilo de 5 o 6 miembros, en donde los alquilos, alquenilo, cicloalquilo,heterocíclico, fenilo o heteroarilo se sustituyen optativamente con uno o más grupos seleccionados de halógeno, CN, CF3, alquilo de C1-C3, -O(alquilo de C1-C3), y NRcRd;R2 se selecciona de alquilo de C1-C6, -O(alquilo de C1- C6), -NH(alquilo de C1-C6), un cicloalquilo de C3-C6 saturado o parcialmente insaturado, fenilo, un heterocíclico de 4 a 6 miembros saturado o parcialmente insaturado, un heteroarilo de 5 o 6 miembros, un arilo bicíclico de 8 a 10 miembros, un heterocíclico bicíclico de 8 a 10 miembros, y un heteroarilo bicíclico de 8 a 10 miembros, en donde los alquilos, cicloalquilo, fenilo, heterocíclicos, heteroarilos y arilo se sustituyen optativamente con uno o más grupos seleccionados de OH, CN, halógeno, oxo (excepto no en fenilo, arilo o heteroarilo) CF3, ciclopropilo, ciclopropilmetilo, -SO2Ri, alquilo de C1-C6, -O(alquilo de C1-C6), -S(alquilo de C1-C6), NReRf, y fenilo, en donde el fenilo se sustituye optativamente con uno o más grupos seleccionados de OH, CN, halógeno, CF3, alquilo de C1-C3, -O(alquilo de C1-C3), y NRgRh;R3 y R4 se seleccionan independientemente de hidrógeno o alquilo de C1-C4 optativamente sustituido con OH, F, -O(alquilo de C1-C3) o cicloalquilo de C3-C6, oR3 y R4 junto con los átomos a los cuales están unidos forman un anillo de 5 o 6 miembros;R5 se selecciona de hidrógeno y CH3, oA es CRaRb, Ra y Rb son hidrógeno y R3 y R5 junto con losátomos a los cuales están unidos forman un anillo de 5 o 6 miembros;R6 se selecciona de hidrógeno, F, OH, -OCH3, alquilo de C1-C3 y ciclopropilo, o ...
Patent CO-6362005-A2 (CO)
Title: Compuestos de multiheteroarilo como inhibidores de prostaglandina d sintasa hematopoyetica y su uso para tratar enfermedades mediadas por prostaglandina d2
Inventor: ENDRES GREGORY W
IPC: C07D403/14
Filed: 2011-04-15
Abstract: Los compuestos multiheteroarilo, su preparación, composiciones farmacéuticas que comprenden estos compuestos, y su uso farmacéutico en la prevención y tratamiento de enfermedades y afecciones mediadas por prostaglandina D2 que pueden modularse por la inhibición de sintasa de prostaglandina D hematopoyética (H-PGDS).
Patent CO-6781532-A2 (CO)
Title: Kit de cuidado bucal incluyendo panel visible de calcomanías
Inventor: LEE DAVID K
IPC: B65D75/36
Filed: 2013-10-04
Abstract: Un kit de cuidado bucal (1000) incluyendo un producto de cuidado bucal (200) y un panel de calcomanías (300); en un aspecto, la invención puede ser un kit de cuidado bucal (1000) que comprende: un empaque (100) ; un cepillo de dientes (200) colocado dentro del empaque (100) ; y un panel de calcomanías (300) colocado dentro del empaque (100), el panel de calcomanías (300) comprende una pluralidad de calcomanías desmontables (301), el panel de calcomanías (300) formando una manga a través de la cual se extiende una porción del cepillo de dientes (200), la pluralidad de calcomanías (301) visible desde el exterior del empaque (100) a través de una porción sustancialmente transparente del empaque (100).
Patent EP-1036993-A2 (EP)
Inventor: ZWEERS WILHELM
IPC: F24D12/02
Filed: 2000-03-09
Abstract: The hydraulic switch (5) on the one hand is connected with the forward flow (23) and back flow (24) of all the boilers (2) and on the other hand with at least one heating circuit forward flow (55) and heating circuit back flow. The heating installation (1) has a horizontally running boiler forward flow collector (3) and a boiler back flow distributor (4).  The collector and the distributor have connections (33,44) suitable for a group of two or more boilers for connecting the heating boiler forward flows and back flows. The collector and the distributor are connected to the hydraulic switch (5) and with it form a prefabricated, transportable structural and installation unit (10).
Patent EP-1057919-A2 (EP)
Inventor: YANAI YUICHI
IPC: D06B3/08
Filed: 2000-05-31
Abstract: It is an object of this invention to provide a liquid ammonia
treatment technology for producing hank yarn without a dyeing
speck. This invention provides a processor for the liquid
ammonia treatment of hank yarn and a method, wherein liquid
ammonia is supplied to cellulose fibers, liquid ammonia is
removed from the hank yarn, the hank yarn is placed under a
pressure reduced condition, hot water or steam is supplied to
the hank yarn, and the hank yarn is placed under the pressure
reduced condition again.
Patent EP-1076325-A2 (EP)
Inventor: HESSING BERND
IPC: H04W28/00
Filed: 2000-07-21
Abstract: The method involves sending a traffic message request from a radio device and a service provider providing at least one message via a base station that is transmitted to the radio device. The traffic message is transmitted as a TMC message by radio, esp. as a short message. The request contains information about the intended use of the toll roads and/or the type of vehicle and/or the length of the position code and only corresp. return traffic messages are transmitted.
Patent EP-1085233-A2 (EP)
Inventor: PERES LASZLO
IPC: F16F9/48
Filed: 2000-08-03
Abstract: The shock absorber (1) has a piston rod (2) with a main piston (12) inserted in a fluid-filled cylinder (3), to divide into two working chambers (13,14). The main piston carries an auxiliary piston (14), which enters an auxiliary cylinder (16) fixed axially in the cylinder (3) at the end of the insertion movement of the main cylinder. The entry opening of the auxiliary cylinder leads to a fluid-filled chamber (18) with a volume varied against a spring force. When the entry opening is closed by the auxiliary piston, the pressure increase in the working chamber (14) assigned to the auxiliary piston opens a valve (19), which forms a connection from the working chamber to the fluid-filled chamber. The fluid exchange between the two working chambers of the cylinder is through a connection of the two working chambers, which run through the auxiliary piston. The opening cross-section to the working chamber is reduced by sliding the auxiliary piston in the auxiliary cylinder.
Patent EP-1084901-A2 (EP)
Inventor: OKANO NAOKI
IPC: A47C7/46
Filed: 2000-08-16
Abstract: A seat back supporting mechanism (5) for movably supporting
a seat back (3) on support members (15) is provided such that a
load exerted on the seat back (3) by a passenger's waist part
upon a rear crash of a vehicle causes a rotation of the entire
seat back (3) from its usual position about its instantaneous
center (5a to 5g) located above the load exerting position,
thereby moving a head rest (4) forward and upward. This seat
back supporting mechanism (5) is constructed to move the
instantaneous center (5a to 5g) of the seat back (3) upward and
forward as the seat back (3) rotates. The passenger's head can
be effectively received upon the rear crash of the vehicle by
moving the head rest (4) forward and upward.
Patent EP-1090871-A2 (EP)
Inventor: PUETTMANN LUDGER
IPC: B66B11/04
Filed: 2000-09-23
Abstract: The drive mechanism consists of a rotary current motor (1), a bolt-coupling/brake (2), a gear (3) and a driving disc (4) all forming an integral unit or machine. The motor is directly connected to the gear housing (7) by means of a coupling's container-lantern (6). The gear's input shaft (11) is in the form of a worm shaft engaging with a worm wheel (12) of the gear and positioned on an intermediate shaft (13).
Patent EP-1094516-A2 (EP)
Inventor: HIRATA KATSUHIKO
IPC: H01L23/373
Filed: 2000-10-17
Abstract: A thermally conductive composition comprises 100
parts by weight of a wax, 0 to 1000 parts by weight of a
tackifier and 10 to 1200 parts by weight of a thermally
conductive filler, and is a gel at room temperature or a
sol at a high temperature of 35 to 100° C and is
reversibly convertible in state. The composition is
used for forming a thermally conductive film on a heat
sink for use in electronic devices for releasing the
heat generated by an electronic component of the device.
Since the composition is in the form of a gel at room
temperature, the thermally conductive film formed from
the composition is unlikely to peel off easily,
rendering the heat sink having the film formed thereon
easy to handle. The film of the composition is
converted to a sol with the heat generated by the
electronic component in use, therefore completely fills
up the clearance between the electronic component and
the heat sink and becomes thinner, consequently
diminishing the thermal resistance between the heat-generating
electronic component and the heat sink and
ensuring heat transfer from the component to the heat
sink with an improved efficiency.
Patent EP-1102217-A2 (EP)
Inventor: KIMURA KENICHI
IPC: G07D7/20
Filed: 2000-11-16
Abstract: In a truth and falsehood determination device 1, a
multiplicity of perforations, which are so fine as to make it
difficult for them to be visually observed and composed of a
multiplicity of background perforations (5, 9) 5 and a multiplicity
of information perforations (6, 10) 6, are disposed in a sttaggered
arrangement with respect to the disposition of stripes having
colors of R, G, B which constitute a color element screen (2)
2 used to determine truth and falsehood as well as the information
perforations (6, 10) 6 are shifted from the backgropund
perforations 5 by a predetermined distance x. Further, the
background perforations (5, 9) 5 and the information perforations
(6, 10) 6 of each row are partially shifted vertically to provide
them with binarized data composed of "0" and "1". With this
arrangement, the truth and falsehood determination device 1 can
prevent forgery and alteration of precious prints.
Patent EP-1085426-A2 (EP)
Inventor: SHIGEMATSU SATOSHI
IPC: G06F15/80
Filed: 2000-09-12
Abstract: A parallel-processing apparatus includes a
plurality of cells, variable-delay circuits, a signal
output unit, a delay counter, and an accumulation unit.
Each cell has a processing circuit for performing
arbitrary processing. The variable-delay circuits are
respectively arranged in the cells, change the signal
propagation delay in accordance with the processing
results of the processing circuits, and are
series-connected over the plurality of cells. The
signal output unit outputs a measurement input signal to
the first variable-delay circuit of a variable-delay
circuit array constituted by series-connecting all the
variable-delay circuits. The delay counter receives the
measurement input signal output from the signal output
unit and a measurement output signal output from the
final variable-delay circuit of the variable-delay
circuit array upon input of the measurement input signal,
and obtains the signal propagation delay time of the
variable-delay circuit array on the basis of the
measurement input and output signals. The accumulation
unit accumulates the processing results of the
processing circuits in the cells on the basis of the
signal propagation delay time of the variable-delay
circuit array. A parallel processing method is also
disclosed.
Patent EP-1022699-A2 (EP)
Inventor: MONAGHAN ANDREW
IPC: G06Q20/00
Filed: 2000-01-13
Abstract: A plurality of self-service terminals (16a,b,c,d) are
connected in a network (18) which is connected by a
communication link (20) to a proxy unit (14). The network
(18) implements an obsolescent (legacy) protocol. A
manager unit (12) is provided to monitor the health of the
terminals and the manager unit (12) operates under the SNMP
standard, which requires that the manager unit (12)
communicates through a network operating under a later
protocol. To enable two-way communication to take place
between the manager unit (12) and the terminal network
(18), a proxy unit (14) is provided which is connected both
to the terminal network (18) and the TCP/IP network (22).
Proxy unit (14) has a table of addresses, one for each of
the terminals (16a,b,c,d) of the terminal network (18) and
receives messages from the manager unit (12) sent in IP
protocol which are intended for a terminal (16). These
messages are translated into a form suitable for
transmission over the terminal network (18). Likewise
messages from a terminal in legacy format are passed over
the terminal network (18) and are received in the proxy
unit (14) where they are converted for onward transmission
over the IP network (22) to the manager unit (12). Thus
the proxy unit (14) is transparent to both the terminal
network (18) and the manager unit (12).
Patent EP-1026685-A2 (EP)
Inventor: SASAKI KAZUO
IPC: G11B23/28
Filed: 2000-01-31
Abstract: A tape cassette is disclosed which includes an
erroneous erasing preventive or write protect device which
includes a plurality of discriminating detectable portions
provided in a cassette body or casing and a discriminating
plug for opening and closing at least one of the
discriminating detectable portions. The discriminating
detectable portions are formed collectively in a single
indented part with no separating walls.
Patent EP-1033205-A2 (EP)
Inventor: FUKUDA TAKANORI
IPC: B25B27/24
Filed: 2000-02-21
Abstract: A tire air valve (core) mounting and dismounting tool (20) includes
a tool head portion (21), a shank portion (22) and a grip portion (23). The tool
head portion (21) has a slot (32) for seizing and holding a valve core head
portion (16), an axial bore (33) for accepting a valve core shaft portion (14) and
its enlarged end (14a). The tool head portion (21) also has annular groove (34)
formed along a cylindrical peripheral surface thereof. Balls (36) are
retained in second bores (35) which are open to the annular groove (34) and
also communicate with the axial bore (33) through openings (37) of a
reduced diameter to allow the balls (36) to partially protrude into the axial
bore (33). A coil spring (38) is anchored and fastened in the annular groove
(34) to act to normally bias the ball (36) radially inwards and leave the balls
(36) protruding into the axial bore (33). When the balls (36) are hit and pushed
down by the valve core shaft's enlarged end (14a), the elasticity of the coil
spring (38) allows the balls (36) to move radially outwards, permitting the
valve core shaft end (14a) to move deeper beyond the balls (36) and then
permitting the balls (36) to restore their biased state, thereby holding the
valve core shaft end (14a) against moving back. Thus, the valve core is
caught by the tool.
Patent EP-1043849-A2 (EP)
Inventor: ARNEY SUSANNE
IPC: H04B10/02
Filed: 2000-03-28
Abstract: An optical communication system which conserves electrical power is
disclosed. Electrical power is conserved in the optical communication system by
coupling a splitter to an optical amplifier. The optical amplifier is configured to
receive optical signals as well as pump light. The splitter provides a portion of the
pump light used in the optical amplifier to other devices (e. g., optical amplifiers,
filters, modulators) of the optical communication system. Providing a portion of the
pump light used in the optical amplifier to other devices in the optical
communication systems conserves electric power by reducing the total electrical
power needed to operate the optical communication system.
Patent EP-1082990-A2 (EP)
Inventor: GREGER LARS
IPC: B01D53/04
Filed: 2000-08-29
Abstract: An assembly, a method and a motor vehicle for cleaning ambient air in the vicinity of an
internal combustion engine (102) having combustion air inlet means (103) and energy
emitting means (104). The assembly (101) further comprises adsorbent means (105) for
adsorbing at least one pollutant when in a first mode of operation and for desorbing the
pollutant when in a second mode of operation. The adsorbent means have an inlet (106) for
polluted ambient air (107, 107') and an outlet (108) for cleaned ambient air (109, 109').
Furthermore, the assembly (101) comprises a pollutant conduit (110) through which the
desorbed pollutant is transferred from the adsorbent means (105) to the combustion air inlet
means (103) when in the second mode of operation, and the adsorbent means (105) are
arranged for being brought into the second mode of operation by means of energy supplied
from the energy emitting means (104).
Patent EP-1165536-A2 (EP)
Inventor: MANZER LEO E
IPC: C07D307/33
Filed: 2000-03-16
Abstract: Cette invention concerne un procédé d'addition de formaldéhyde à l'atome de carbone α de lactones pour la production d'α-méthylènelactones, et spécifiquement d'α méthylène-η-butyrolactone.
Patent EP-1189934-A2 (EP)
Inventor: HILL FERGAL CONAN
IPC: C07K14/245
Filed: 2000-05-12
Abstract: L'invention concerne un monomère polypeptidique capable d'une oligomérisation. Ce monomère comprend un polypeptide qui active le repliement de la protéine, inséré dans la séquence d'une sous-unité d'une protéine d'échafaudage oligomérisable.
Patent EP-1187702-A2 (EP)
Inventor: DEGEN KLEMENS
IPC: B25B5/16
Filed: 2000-05-12
Abstract: The invention relates to a clamp clip, comprising a first clamping jaw support (2) which can be displaced along a slide bar (1) and fixed thereon by applying a tilting moment. Said clamping jaw support comprises a first clamping jaw (3), certain areas of which lie at a distance from the slide bar (1) and a second clamping jaw support (4) which is located and substantially fixed in the area of one end of the slide bar. The second clamping jaw support comprises a second clamping jaw (5) which is located opposite the first clamping jaw (3) and which is displaced towards said first clamping jaw (3) when the clamping jaw support is impinged upon by an eccentric pressure element (6), located at the end of the slide bar. An improvement is planned, whereby the second clamping jaw support (4) can be pivoted about a shaft (13) which fixes it to the slide bar (1). The eccentric pressure element (6) acts upon a pressure shoulder (7) of the second clamping jaw support (4) which obliquely crosses the slide bar (1).
Patent EP-1200559-A2 (EP)
Inventor: EDGE ALBERT
IPC: A61K35/12
Filed: 2000-07-24
Abstract: L'invention concerne des cellules musculaires et leurs méthodes d'utilisation. Dans un mode de réalisation, l'invention concerne des compositions de cellules musculaires du squelette transplantables et leurs procédés d'utilisation. Dans un autre mode de réalisation, les cellules musculaires peuvent être transplantées dans des patients présentant des troubles caractérisés par une fonction cardiaque insuffisante, par exemple une insuffisance cardiaque globale, par l'administration de myoblastes squelettiques audit sujet. Les cellules musculaires peuvent être autologues, allogéniques ou xénogéniques par rapport au receveur.
Patent EP-1272513-A2 (EP)
Inventor: BOCK ELISABETH
IPC: C12N5/0793
Filed: 2000-09-07
Abstract: La présente invention concerne la protéine Mts1, exprimée dans les astrocytes de la substance blanche de la moelle épinière. Ladite expression augmente de façon significative suite à une lésion du nerf grand sciatique ou à une lésion de la racine postérieure, en particulier dans les astrocytes entourant le funiculus dorsal contenant les principaux prolongements des neurones sensitifs primaires atteints. Les protéines Mts1 administrées de façon extracellulaire favorisent une excroissance des neurites des cellules neuronales. La présente invention concerne également des compositions et des méthodes utilisées dans le traitement de divers états neurologiques caractérisés par la mort, la dégénération ou la lésion des cellules neuronales.
Patent EP-1227894-A2 (EP)
Inventor: NASS RUEDIGER
IPC: C08J7/046
Filed: 2000-09-01
Abstract: La présente invention concerne la réalisation d'un revêtement en particulier sur de l'aluminium. Selon l'invention, une couche est déposée sur l'aluminium, ladite couche est traitée à la chaleur et subit finalement un traitement ultérieur. Le procédé permet d'obtenir de meilleures caractéristiques de surface.
Patent EP-1224316-A2 (EP)
Inventor: SINHA SUBHASH C
IPC: C07D493/04
Filed: 2000-10-06
Abstract: Cette invention a trait à de nouvelles épothilones d'alkyle - 13 inférieur correspondant à la formule (IA). Dans cette formule, R1 représente un méthyle, un hydroxyméthyle, un halométhyle, un méthylthio ou un méthoxy, R2 représente un hydrogène ou un méthyle, R3 représente un alkyle inférieur et Z représente un oxygène ou une liaison. L'invention concerne également des intermédiaires et un procédé de préparation de ces épothilones d'alkyle - 13 inférieur ainsi que de préparation d'épothilones en général. Elle porte, de surcroît, sur une composition pharmaceutique renfermant ces épothilones d'alkyle - 13 inférieur ainsi que sur l'utilisatio
Patent EP-1237555-A2 (EP)
Inventor: MOSELEY WILLIAM M
IPC: A61P15/18
Filed: 2000-12-04
Abstract: L'invention concerne une composition d'implant contenant de l'acétate de mélengestrol (MGA) et de l'acétate de trenbolone (TBA), qui augmente la performance de croissance, qui supprime l'oestrus et qui prévient la gestation chez les génisses. De préférence, l'acétate de mélengestrol (MGA) et l'acétate de trenbolone (TBA) peuvent être compris dans une même granule, ou dans des granules séparées.
Patent EP-1231897-A2 (EP)
Inventor: DRIZEN ALAN
IPC: A61K9/06
Filed: 2000-11-08
Abstract: L'invention concerne des compositions semi-solides de médicaments à libération lente basées sur l'acide hyaluronique et es sels, et concerne plus particulièrement la fabrication et l'utilisation de telles compositions.
Patent EP-1237506-A2 (EP)
Inventor: FITZ MATTHEW J
IPC: A61F2/966
Filed: 2000-12-12
Abstract: L'invention concerne un système de déploiement de stent à élément intérieur renforcé. Ce système comprend un stent auto-extensible dans une condition contractée placé sur une extrémité distale d'un cathéter d'administration et sur une gaine rétractable couvrant le stands. Le cathéter d'administration est introduit à travers un cathéter guide au niveau d'un emplacement désiré dans la lumière corporelle d'un patient. Un fois le stent placé dans l'emplacement cible, la gaine est retirée en tirant sur la tige afin d'exposer le stent auto-extensible. L'élément intérieur renforcé fournit une résistance de compression longitudinale au cathéter d'administration, tout en permettant une flexibilité de navigation à travers un réseau vasculaire sinueux.
Patent EP-1126368-A2 (EP)
Inventor: ANDERSON TIMOTHY D
IPC: G06F9/302
Filed: 2001-02-19
Abstract: A data processing system (1300) is provided with a
digital signal processor (DSP) (1301) that has an instruction
set architecture (ISA) that is optimized for intensive numeric
algorithm processing. The DSP has dual load/store units (.D1,
.D2) connected to dual memory ports (T1, T2) in a level one
data cache memory controller (1720a). The DSP can execute two
aligned data transfers each having a length of one byte, two
bytes, four bytes, or eight bytes in parallel by executing two
load/store instructions. The DSP can also execute a single
non-aligned data transfer having a length of four bytes or
eight bytes by executing a non-aligned load/store instruction
that utilizes both memory target ports.