baber/WOPTO huggingface dataset:
Patent EP-1021167-B1 (EP)
Inventor: SHIRLEY BRET A
IPC: A61P3/10
Filed: 1998-09-08
Granted: 2009-02-18
Abstract: Disclosed are multivesicular liposomes (MVLs) containing IGF-I with substantially full bioavailability, wherein the loading of the IGF-I into the liposomes is modulated by adjusting the osmolarity of the aqueous component into which the agents are dissolved prior to encapsulation. In the making of MVLs, the process involves dissolving the IGF-I, an osmolarity excipient, and a pH modifying agent sufficient to solubilize the IGF-I in a first aqueous component used during manufacture of the MVLs. To increase the loading of the IGF-I, the osmolarity of the aqueous component used during manufacture of the MVLs is reduced, whereas the osmolarity of the aqueous component is increased to obtain the low load formulations. The rate of release of the active agent into the surrounding environment in which the liposomes are introduced can be simultaneously controlled by incorporating into the lipid component used in the formulation at least one long chain amphipathic lipid. Use of the long chain amphipathic lipid in the lipid component is particularly helpful in controlling the release rate from high drug load formulations.
Patent EP-1037531-B1 (EP)
Inventor: RODGERS MICHAEL A J
IPC: A61K41/00
Filed: 1998-11-12
Granted: 2004-09-29
Abstract: The present invention in general terms includes a method of treating cancerous cells containing a pigment, the method including irradiation of the cells with light of comprising the steps: (1) subjecting the cancerous cells to relatively high power light so as to substantially reduce the amount of the pigment in the cells; (2) treating the cancerous cells with one or more photosensitizing agent; followed by (3) subjecting the cancerous cells to relatively low power light so as to activate the photosensitizing agent(s).
Patent EP-0957944-B1 (EP)
Inventor: MAYER HUBERT
IPC: A61K35/12
Filed: 1998-11-30
Granted: 2004-05-06
Abstract: The invention relates to a bone matrix which can be obtained by: (a) starting out from an explantation and obtaining osteogenic precursor cells or starting out from an osteogenic cell line; (b) optionally expanding the obtained osteogenic precursor cells or the osteogenic cell line in-vitro; (c) permitting the osteogenic precursor cells to propagate, said cells being obtained according to (a) or expanded according to (b), or permitting the cell line to propagate, said cell line being inserted according to (a) or expanded according to (b), and optionally obtaining osteogenic cells; (d) separate from step (c), permitting the osteogenic cells to synthesize in-vitro in an extracellular matrix, said cells being obtained according to (a) or expanded according to (b), or permitting the cell line to synthesize in-vitro in an extracellular matrix, said cell line being introduced according to (a) or expanded according to (b); (e) optionally liberating the synthesized matrix from cells and optionally obtaining a cell-free bone matrix; (f) populating the obtained cell-free bone matrix once more with osteogenic cells which have been obtained according to (c) and optionally obtaining a populated bone matrix by using osteogenic cells.
Patent EP-1045832-B1 (EP)
Inventor: MAIER ROLAND
IPC: C07C271/24
Filed: 1998-12-08
Granted: 2005-03-23
Abstract: La présente invention concerne des uréthanes, ainsi que leurs analogues thio et dithio, correspondant à la formule générale (I), dans laquelle m, n, A, X, Y et les groupes R1 à R8 correspondent à la définition donnée dans la revendication 1, leurs énantiomères, leurs diastéréomères et leurs sels, en particulier, leurs sels d'addition d'acide physiologiquement compatibles, qui présentent de précieuses caractéristiques, en particulier, un effet inhibiteur vis-à-vis de la biosynthèse du cholestérol. L'invention concerne également des médicaments contenant ces composés, leur utilisation et leur procédé de production.
Patent EP-1040687-B1 (EP)
Inventor: MACDANIEL DAVID
IPC: H04M3/42
Filed: 1998-12-15
Granted: 2004-08-11
Abstract: A system is provided for logging digital messages and forwarding them outside a proprietary telecommunications network. The system includes a service logic program ('SLP') which determines whether the message is to be forwarded outside the proprietary system. If the message is to be forwarded outside the system, the SLP (102) sends it to the main relay, which logs the message to a log file, and forwards it to a discriminator. The discriminator forwards the message to a sub-relay (105-106), which is connected to a vendor application. The sub-relay (105-106) forwards the message outside the proprietary telecommunication system, to the vendor application.
Patent EP-0933187-B1 (EP)
Inventor: REES HERBERT
IPC: B29C43/00
Filed: 1999-01-14
Granted: 2003-10-08
Abstract: A compression mold (10) and blow mold (12) are provided in spaced relationship to each other. A preform (18) is formed from a preform precursor (16) in the compression mold (10) and transferred to a blow mold (12) while maintaining the spaced relationship between the compression mold (10) and blow mold (12), and a container (32) is formed from the preform (18) in the blow mold (12). <IMAGE>
Patent EP-0950550-B1 (EP)
Inventor: BRAUN DIETER DIPL-ING
IPC: B60D1/06
Filed: 1999-03-10
Granted: 2003-05-28
Abstract: The coupling includes a mechanically actuated coupling element (6). When the coupling carrier housing (1) is in a coupling position, the coupling element is positioned behind the coupling ball (2), and a hydraulically actuated coupling element (5) is positioned in front of the coupling ball. The hydraulic coupling element is connected to a unit of hydraulic master cylinder (10) and a gas spring, coupled to the cylinder via a pressure compensator (14). The spring acts on the coupling element after the mechanical coupling element is moved into coupling position with the coupling ball.
Patent EP-0958910-B1 (EP)
Inventor: FINKE UDO
IPC: B29C48/10
Filed: 1999-05-19
Granted: 2003-02-12
Abstract: The properties of the cooled film (12') are continuously measured and process variables relating to the film production (2,3,4) are controlled in real time according to the measured quality parameters.   An Independent claim is included for the apparatus for the production of the plastic film by a tube blowing process. The apparatus comprises an extruder (4) with a blowing die (5) with an annular plastics extrusion nozzle (11) and internal air nozzles (21,22) for forming a tube and a tube cooling area enclosed by a housing (45) attached to the blowing die. Preferred Features: Cooling air conditioning, strength and flow rate are also controlled according to the measured film properties. Film transparency is also determined and used as a process control variable. Purified, temperature-controlled flushing air envelopes the entire tubular film in the air treatment zone and moves in the same direction as the film.
Patent EP-0976453-B1 (EP)
Inventor: GAMBLE KIMBERLY R
IPC: B01L3/00
Filed: 1999-06-25
Granted: 2004-05-19
Abstract: A microplate assembly with closure comprises a microplate base 101 having a geometric array of wells 103. Vials 113 of borosilicate glass inserted into the wells comprise flanges on the top portion of the vials. Closure 117 comprises an array of caps 119 having a complementary geometric pattern to the wells of the microplate base. The caps each comprise a septum and are connected by a thin membrane 121. Each cap comprises a sidewall 403 having a vial engagement ring which snaps over the flange 115 of the vials. Septum openings 135 in the caps extend through the top of the caps and provide a means to fill and evacuate the vials with a penetration device passing through the septa of the caps of the closure. <IMAGE>
Patent EP-0987070-B1 (EP)
Inventor: WURMBACH LOTHAR
IPC: B44B5/00
Filed: 1999-08-09
Granted: 2002-01-23
Abstract: A press for the stamping of plates, in combination with a cutting apparatus, provided with two magazines that are formed on the press table, while the magazines accommodate registers that are positioned horizontally with respect to one another, whereby each register encompasses a series of holders for stamping tools that have the same or differing width. The holders are positioned vertically with respect to one another. The stamping tools are combined in pairs and, by computer control, can be positioned at the height of the press table by vertical drives and horizontal drives and into correspondence with the plate design that is to be stamped into a sheet metal strip. The stamping tool pairs can also be slid into the press, and be removable therefrom, by additional horizontal drives using the press, it is possible to stamp out plates, particularly vehicle license plates, having a design in which the individual symbols are either in registered layout or in a free (or non-registered) layout.
Patent EP-1001338-B1 (EP)
Inventor: ZGARBA TONY
IPC: G06F9/06
Filed: 1999-11-10
Granted: 2007-10-17
Abstract: A method of round-trip engineering source code from a software model, and in particular a method of forward engineering code previously reverse engineered into a software model whereby to generate updated source code without any changes to the code not changed in the model, and without using obtrusive code markers in the source code. Elements from the original source code represented by the model are placed in a meta-model, and compared to a similar meta-model of the software model. Appropriate changes and additions are made in the source code to elements which have been changed in the software model. The rest of the code in the software model remains untouched.
Patent EP-1049746-B1 (EP)
Title: Procedes relatifs a la purification d'une dispersion et a la fabrication d'encre pour l'impression a jet d'encre
Inventor: CHAN MICHAEL K
IPC: C09C1/56
Filed: 1999-01-29
Granted: 2003-08-20
Abstract: L'invention concerne un procédé relatif à la purification et à la classification d'une dispersion renfermant des particules stabilisées comportant des contre-ions, des ions et une espèce libre. La solution peut comprendre un milieu aqueux, un milieu solvant, ou une combinaison des deux, et elle peut comprendre plus d'un type de milieux aqueux et/ou solvant. Le procédé comprend au moins les étapes suivantes, dans un ordre quelconque: action visant à éliminer sensiblement les particules dont la taille est supérieure à environ 5 micron, de préférence celles dont la taille excède 0,5 micron; action visant à éliminer sensiblement l'espèce libre; et échange d'au moins une partie des contre-ions faisant partie des particules stabilisées. Le procédé considéré est particulièrement utile dans la purification des dispersions dont les particules colloïdales ioniques stabilisées sont des particules de noir de carbone ayant des groupes organiques liés qui comprennent au moins un groupe ionique, ou au moins un groupe ionisable, ou des mélanges de ces groupes.
Patent EP-1055726-B1 (EP)
Inventor: KOMEDA TOSHIHIRO
IPC: C12N15/81
Filed: 1999-02-18
Granted: 2006-09-06
Abstract: This invention relates to a promoter for dihydroxyacetone synthase gene from Candida boidinii; an expression cassette or vector comprising the promoter and a heterologous gene; a transformant transformed with this vector, and a method for producing an expression product of the heterologous gene which comprises culturing the transformant to express the heterologous gene.
Patent EP-1052971-B1 (EP)
Title: Produit moussant pour le nettoyage de la peau
Inventor: VINSKI PAUL
IPC: A61Q19/10
Filed: 1999-01-19
Granted: 2003-08-27
Abstract: L'invention porte sur un produit moussant pour le nettoyage de la peau présenté dans un distributeur mécanique non générateur d'aérosols comportant un réservoir de liquide, une tête distributrice munie d'un logement abritant une pompe, et un matériau écran placé sur la trajectoire du liquide pour le convertir en mousse, et un tube plongeur transportant le liquide du réservoir à la tête distributrice. La composition de nettoyage, pratiquement exempte d'émollients hydroinsolubles, contient un tensio-actif anionique et un tensio-actif amphotérique de structure (I) où R est un alkyle gras C6 à C22; R1 est choisi parmi H, C¿2?H4COOH et C2H4COONa; et R?2¿ est choisi parmi COONa, CH¿2?CHOHCH2SO3Na, C2H4COONa, CH2COOCH2COOH et CH2COOCH2COONa.
Patent EP-1062477-B1 (EP)
Inventor: DALL AGLIO CARLO
IPC: G01B7/00
Filed: 1999-02-26
Granted: 2002-01-09
Abstract: A checking head (T) includes a casing (1), an arm (2) with a feeler, movable with respect to the casing, and a sensor, such as an inductive position transducer (5). An electronic identifier (27) is fixed to a frame coupled to the head (T), for storing identifying data relevant to the head, information relating e.g. to the configuration and calibration features of the head, and/or compensation values obtained in the 41 course of the calibration phase carried out on a suitable testing equipment.
Patent EP-1064531-B1 (EP)
Inventor: GOEHDE WOLFGANG
IPC: B01L3/02
Filed: 1999-03-15
Granted: 2003-11-19
Abstract: An apparatus for dispensing a measured quantity of a liquid has a container holding a quantity of liquid to be measured and dispensed and a conduit with an inlet end, an outlet end and a measuring section having a known volume. A sensor determines when the measuring section contains liquid. A passage with a first valve is provided for delivering liquid from the container to the conduit inlet end and air under pressure urges liquid from the container to the conduit. A source of air under pressure is connected to the conduit and a second valve controls delivery of air to the conduit from the source. A control connected to the sensor and to the first and second valves sequentially closes the second valve and opens the first valve to cause flow of liquid from the container to the conduit until the sensor determines that the measuring section contains liquid, and then closes the first valve and opens the second valve to admit air to the conduit, thereby expelling a measured quantity of liquid from the outlet end.
Patent EP-1082824-B1 (EP)
Title: Techniques de mesure pour le transfert intercellulaire assiste par station mobile (maho) en diversite et interfrequence
Inventor: RAJARAM RAMESH
IPC: H04B7/12
Filed: 1999-05-05
Granted: 2006-07-26
Abstract: La présente invention permet, grâce à une synchronisation stratégique et à des commutations optimisées, de réaliser le transfert intercellulaire assisté par station mobile (MAHO) en diversité et interfréquence dans des systèmes d'accès cellulaire à réception continue. On assure une synchronisation stratégique en évitant la non réception des bits de commande de puissance. Le terminal mobile peut par exemple effectuer les mesures de diversité sur les huit derniers bits d'une sous-trame de transmission descendante IS-95. On optimise la commutation, par exemple, en stockant les configurations d'antenne d'une première antenne avant de commuter sur une deuxième antenne de façon que les configurations d'antenne peuvent être réutilisées pour le retour sur la première antenne. Les techniques précitées et autres techniques de mesure de l'invention permettent de faire bénéficier les systèmes cellulaires à réception continue des avantages du transfert intercellulaire assisté par station mobile en diversité et interfréquence.
Patent EP-1095128-B1 (EP)
Inventor: BETTIOL JEAN-LUC PHILIPPE
IPC: C11D3/00
Filed: 1999-07-12
Granted: 2005-04-20
Abstract: The present invention relates to a product of reaction between a primary amine and one or more active ingredients. By the present invention, there is provided a release of the active component over a longer period of time than by the use of the active itself.
Patent EP-1128077-B1 (EP)
Inventor: PARES ISANTA ALBERT
IPC: B29C45/16
Filed: 1999-10-13
Granted: 2004-04-07
Abstract: Clip being constructed by combining a base body (1), plastic in nature, of noticeable stiffness, with the standard head (2) for coupling to the plate to be fastened, and the also standard locking boss (4) which can contract elastically, intended for coupling into the hole in the sheet or plate acting as support, and a collar (8) preferentially of rubber or similar material, serving as sealing element, formed between head (2) and locking boss (4), having the special characteristic that the base body (1) includes in the outside part of its head (2) an axial access (9) with channels (10) which are elbowed outwards and open into a perimetric neck (7) made in the section where the collar (8) is formed, all of the foregoing being such that first the base body (1) is injected into the mould corresponding and, afterwards, the collar is obtained in an over-moulding operation, in a second mould in which the previously obtained base body (1) participates. <IMAGE>
Patent EP-1128841-B1 (EP)
Inventor: SCHWARZ HANS-PETER
IPC: C12N15/85
Filed: 1999-11-10
Granted: 2004-04-28
Abstract: The invention relates to a pharmaceutical preparation for treating blood-clotting disorders which is characterized in that it contains at least one protein selected from the group of pro-proteins of the blood clotting and additionally contains a coagulation-physiologically inert receptor binding competitor. The invention also relates to the medical application of said preparation.
Patent EP-1124796-B1 (EP)
Inventor: FARNHAM WILLIAM BROWN
IPC: H01M6/22
Filed: 1999-10-26
Granted: 2004-12-22
Abstract: A process for synthesizing an olefinic composition represented by the formula: CF2=CF(CF2CF2)nSO2F where n = 1 to 5 comprising  (a) contacting CF2ClCFCl(CF2CF2)nI, wherein n = 1 to 5, with Na2S2O4 and NaHCO3 in a mixture of water and an aprotic polar solvent at a temperature in the range of room temperature to 110 DEG C, to form CF2ClCFCl(CF2CF2)nSO2Na; (b) contacting the said CF2ClCFCl(CF2CF2)nSO2Na with Cl2 in water or a mixture of water and an aprotic polar solvent at a temperature in the range of 0-200 DEG C to form CF2ClCFCl(CF2CF2)nSO2Cl; (c) contacting the said CF2ClCFCl(CF2CF2)nSO2Cl with a univalent metal fluoride in an anhydrous aprotic polar solvent to form CF2ClCFCl(CF2CF2)nSO2F; (d) contacting said CF2ClCFCl(CF2CF2)nSO2F with Zn in an alcohol or mixture of acetic acid and alcohol to form CF2=CF(CF2CF2)nSO2F; and, (e) separating the product.
Patent EP-1172428-B1 (EP)
Inventor: YAMANA MASAYUKI
IPC: C09K3/18
Filed: 1999-12-14
Granted: 2011-06-01
Abstract: L'invention concerne une dispersion aqueuse hydrophobe et oléophobe, renfermant A) un homopolymère ou un copolymère d'au moins un élément choisi parmi les composés polymérisables pourvus d'un groupe perfluoroalkyle ou perfluoroalkényle, et d'un groupe acrylate ou méthacrylate, ou un copolymère de ceux-ci avec un composé polymérisable, B) un solvant organique qui est du tripropylène glycol, et C) un tensioactif. Cette dispersion présente une hydrophobicité et une oléophobicité durables ainsi qu'une excellente stabilité au stockage.
Patent EP-1153043-B1 (EP)
Inventor: KRAMER ANDREAS
IPC: C08F2/38
Filed: 1999-09-18
Granted: 2004-10-13
Abstract: The invention relates to a process for the preparation of polymers containing N->O terminal groups and to compositions comprising polymers obtained by this process. The process comprises polymerizing by atom transfer radical polymerization (ATRP) an aliphatic monomer of oligomer containing ethylene groups in the presence of a polymerization initiator.
Patent IT-1280317-B1 (IT)
Title: Electric socket with incorporated interlock
Inventor: ANSIDERI MARCELLO
IPC: H02H/
Filed: 1995-01-20
Granted: 1998-01-15
Abstract: The invention consists of an electric socket with internal block capable of movement controlled by the electric plug inserted into it, following which there is movement from an "off" position - in which the plug electrodes are insulated from the phase electrodes of the socket and the plug is mechanically free for removal  - to an "on" position in which the plug electrodes are electrically connected to the socket electrodes and the mechanical parts of the plug are mechanically coupled with the corresponding parts of the socket to impede their release, except by means of the movement which returns the internal block of the socket to the "off" position. <IMAGE>
Patent IT-1264140-B1 (IT)
Inventor: TURRI STEFANO
IPC: C08G63/682
Filed: 1993-04-19
Granted: 1996-09-16
Abstract: Fluorinated thermoplastic elastomers having a block structure:    -[-Rf-H1-H2-H1-]-    where -Rf- is a perfluoropolyoxyalkylene sequence of formula:    -CF2O-(CF2CF2O)m-(CF2O)n-CF2-   with m/n = 0.2 + 5, H1 and H2, equal or different from each other, are bivalent radicals having arylene, alkylarylene, alkylene or cycloalkylene structure, optionally containing fluorine and/or other heteroatoms selected among oxygen, sulphur, nitrogen. Such products are obtainable by utilizing a perfluoropolyoxyalkylene diol having a functionality at least equal to 1.97, preferably at least equal to 1.99, and are characterized by a tensile strength at 23 DEG C at least 50% higher than that of the corresponding polyesters obtained starting from perfluoropolyoxyalkylene diols having a functionality not higher than 1.96.
Patent IT-1265320-B1 (IT)
Title: Procedimento per la preparazione di silico-allumine amorfe cataliticamente attive
Inventor: PEREGO CARLO
IPC: B01J21/12
Filed: 1993-12-22
Granted: 1996-10-31
Abstract: Un gel di silice e allumina amorfo e micro/mesoporoso con grandezza controllata dei pori, con area superficiale di almeno 500 m2/q e con un rapporto molare SiO2/Al2O3 di almeno 30% viene preparato mediante idrolisi e gelificazione di un tetraalchil ammonio idrossido, un alluminio trialcossido e un tetraalchil ortosilicato operando ad una temperatura di ebollizione, alla pressione atmosferica, di qualsiasi alcool che si sviluppa quale sottoprodotto di detta reazione di idrolisi, senza eliminazione o senza sostanziale eliminazione di detti alcoli dall'ambiente di reazione; e sottoponendo il gel così ottenuto ad essiccamento e calcinazione.Il gel così ottenuto è un catalizzatore attivo nelle reazioni di conversione degli idrocarburi, specie nella isomerizzazione ed oligomerizzazione delle olefine leggere, ad esempio nella oligomerizzazione di propilene a dare tagli idrocarburici liquidi utili nella formulazione di benzina e di jet fuel.
Patent IT-1275359-B1 (IT)
Title: Terminale per cavo elettrico
Inventor: CICOGNA FRANCESCO
IPC: H01B17/26
Filed: 1994-02-11
Granted: 1997-08-05
Abstract: In un terminale per cavo elettrico ad alta tensione si interrompe il cavo elettrico ad un'altezza predeterminata dall'ingresso nel terminale e si realizza il collegamento elettrico fino alla connessione con la linea aerea mediante un elemento conduttore rigido; l'elemento conduttore rigido, preferibilmente un tubo di rame, possiede un rivestimento elastomerico alettato ed è sostenuto da un basamento isolante preferenzialmente in resina epossidica; il complesso formato da basamento in resina epossidica ed elemento conduttore rigido porta il campo elettrico alla superficie ad un valore compatibile con la rigidità dielettrica dell'aria e possiede una lunghezza sufficiente a formare una linea di fuga adeguata all'ambiente di installazione.
Patent IT-1273787-B1 (IT)
Title: Dispositivo di propulsione con un motore idraulico e una trasmissione meccanica a valle
Inventor: ERWIN MEISINGER
IPC: A01D69/03
Filed: 1994-02-18
Granted: 1997-07-10
Abstract: L'invenzione si riferisce a un dispositivo di propulsione con un motore idraulico (1) ed una trasmissione meccanica inserita a valle.Sono previsti due innesti di frizione (7, 8) azionabili idraulicamente, attraverso i quali il motore elettrico può essere collegato con la trasmissione. Uno degli innesti di frizione agisce come freno ed adempie alla funzione di un freno ausiliario e/oppure di stazionamento. Secondo l'invenzione gli innesti di frizione (7, 8) sono azionabili attraverso una conduttura (6) comune della pressione di comando. L'azionamento ha luogo in modo tale che il primo innesto a frizione, servente al collegamento del motore idraulico con la trasmissione, nel caso di pressione di comando applicata viene chiuso e, nel caso di pressione di comando diminuente, é aperto. In tal modo il motore