baber/WOPTO huggingface dataset:
Patent EA-017271-B1 (EA)
Title: Method for detecting permissible tralcoxidime doses for human and animals and derivatives thereof
Inventor: LITVINKO NATALIYA MIKHAILOVNA
IPC: C12Q1/44
Filed: 2009-12-03
Abstract: The invention relates to clinical biochemistry, biotechnology and medicine, in particular to a method of detecting permissible tralkoxydim doses and derivatives thereof in humans and animals based on reproduction in vitro lipolytic components of digestion action and can be used for pre-testing toxicity of novel biologically active compounds having pesticide activity. According to the invention a method is disclosed for detecting permissible tralkoxydim doses for humans and animals based on modeling digestion conditions characterized in detecting change of activity of pancreatic phospholipase Aby determining the content of phospholipase metabolites involving methemoglobin in kinetic regime using difference spectophotometry (AD) and including: a) preparation of first check sample comprising micellae of phosphatidylcholine of egg yolk or natural phosphatidylserine emulsified by bile acid with ratio phospholipid/bile acid 1:2-3 in buffer solution at pH 7.4-8.2 in the presence of CaCland solution of methemoglobin in tris-HCl buffer, preparation of second test sample comprising phospholipase Aand micellae of phosphatidylcholine of egg yolk or natural phosphatidylserine emulsified by bile acid in buffer solution at pH 7.4-8.2 in the presence of CaCland solution of methemoglobin in tris-HCl buffer, and recording the difference spectophotometry (AD) of said samples; b) preparation of third test sample pesticide being tested in suitable solvent, phospholipase A, micellae of phosphatidylcholine of egg yolk or natural phosphatidylserine emulsified by bile acid in buffer solution at pH 7.4-8.2 in the presence of CaCland solution of methemoglobin in tris-HCl buffer, and forth test sample comprising said solvent and, if necessary pesticide being tested, micellae of phosphatidylcholine of egg yolk or natural phosphatidylserine emulsified by bile acid in buffer solution at pH 7.4-8.2 in the presence of CaCland solution of methemoglobin in tris-HCl buffer, and recording the difference spectophotometry (AD) of said samples; c) subsequent calculation of change of the enzyme activity level established in the control by known arts and determining pesticide as safety provided the change of the enzyme level in its presence within at least 20% of the control. A reactant or a preparative pesticide form can be used as a compound to be tested, 3α,12α-di- and 3α,7α,12α-trihydroxycholanic acids (deoxycholic and cholic acids correspondingly). The use of phospholipotic reaction as a simple model of a process for destruction of food phospholipids provides to reliably evaluate pesticide safety for organisms of humans and animals. The inventive express-method has an obvious advantage since there is no need to perform durable tests using laboratory animals and creates favourable conditions for determining pesticides of new generations among a wide range of plants protection means safety for a human.
Patent EA-018122-B1 (EA)
Title: Method for atomic absorption measurements
Inventor: BUZUK ALEXANDER ALEXANDROVICH
IPC: G01J3/42
Filed: 2010-06-29
Abstract: The invention relates to atomic absorption spectrophotometry and is suitable for use during atomic absorption analysis and spectral instrument engineering. The object of the invention is to increase the accuracy of measurement. The object in the method of atomic absorption measurements is realized by defining the upper and lower limits of atomic vapor density variation and by is inserting into the electrothermal atomizer a probe, while the temperature of the electrothermal atomizer is changed to acquire the target density of the atomic vapor therein. At the same time the atomizer temperature is abruptly increased after lowering the density of the atomic vapor to equal with or lower than the minimal limit and is set no higher than the atomizer destruction temperature, whereby the high temperature maintenance duration is set no longer than the lifetime of atomic vapors in the atomizer.
Patent EA-016974-B1 (EA)
Title: Package with double hinged connector
Inventor: WEISS JACQUES
IPC: B65D85/10
Filed: 2008-07-18
Abstract: A container for smoking articles comprises at least two hingedly connected packs, each for housing a separate bundle of smoking articles. The container comprises a first pack having a first wall; a second pack having a first wall; and a separate connector (10). The separate connector comprises a first panel (12) with opposed first and second edges; a second panel (14) comprising a first sub-panel (16) hingedly connected to the first panel (12) along the first edge and a second sub-panel (18) hingedly connected to the first sub-panel (14) along a first fold line; and a third panel (20) comprising a first sub-panel (22) hingedly connected to the first panel (12) along the second edge and a second sub-panel (24) hingedly connected to the first sub-panel (22) along a second fold line.; The first panel (12) of the separate connector (10) is affixed to the first wall of the first pack and the second sub-panels (14, 24) of the second (14) and third (20) panels of the separate connector (10) are affixed to the first wall of the second pack.
Patent EA-017099-B1 (EA)
Title: Wedge and socket assembly
Inventor: KUBO KENNETH
IPC: F16G11/00
Filed: 2009-06-19
Abstract: A socket and wedge assembly that securely holds wire rope and is easy to release includes a collapsible wedge. The wedge collapses at the front, narrowed end to utilize the high pressures at the front end of the wedge in effecting the collapse and releasing the rope. The wedge includes a movable element that pivots and/or translates to facilitate a quick and reliable collapse of the wedge and release of the wire rope. The wedge includes a cavity to at least partially exhaust the fumes created from cutting the support with a torch for release of the wire rope.
Patent EA-038542-B1 (EA)
Title: Fusion proteins for treating gram-positive bacterial infections
Inventor: MILLER STEFAN
IPC: C12N9/52
Filed: 2010-06-28
Abstract: The invention relates to antimicrobial agents against Gram-positive bacteria, in particular to fusion proteins composed of an enzyme having the activity of degrading the cell wall of Gram-positive bacteria and an additional peptide stretch fused to the enzyme at the N- or C-terminus. Moreover, the invention relates to nucleic acid molecules encoding said fusion protein, vectors comprising said nucleic acid molecules and host cells comprising either said nucleic acid molecules or said vectors. In addition, the invention relates to said fusion protein for use as a medicament, in particular for the treatment or prevention of Gram-positive bacterial infections, as diagnostic means or as cosmetic substance. The invention also relates to the treatment or prevention of Gram-positive bacterial contamination of foodstuff, of food processing equipment, of food processing plants, of surfaces coming into contact with foodstuff, of medical devices, of surfaces in hospitals and surgeries. Further, the invention relates to pharmaceutical compositions comprising said fusion protein.
Patent EA-025736-B1 (EA)
Title: Apparatus and process for producing crystals
Inventor: MIZRAHI YOSEF
IPC: C01D9/04
Filed: 2012-03-30
Abstract: A reactor for producing crystals from soluble salts wherein carrying out reaction and/or solvent extraction and/or crystallization are provided. The reactor consists of three sections. An upper section includes a decanter comprising a vertical vessel having a horizontal weir at the top of the decanter and an outlet for removing a light phase at the top of the decanter. A lower section is a crystallizer comprising a coaxial draft tube and further comprising at least one feed pipe, an agitator located inside the draft tube and one or more outlets at the bottom for crystal slurry removal. An intermediate section includes at least one coaxial vertical baffle, there being a gap between the draft tube and the coaxial vertical baffle, where the gap is adjustable by moving the vertical baffle up or down.
Patent EA-030226-B1 (EA)
Title: Antibodies reactive with b7-h3, immunologically active fragments thereof and uses thereof
Inventor: LOO DERYK T
IPC: C07K16/00
Filed: 2011-03-01
Abstract: The present invention relates to antibodies and their fragments that are immunoreactive to the mammalian, and more particularly, the human B7-H3 receptor and to uses thereof, particularly in the treatment of cancer and inflammation. The invention thus particularly concerns humanized B7-H3-reactive antibodies and their immunoreactive fragments that are capable of mediating, and more preferably enhancing the activation of the immune system against cancer cells that are associated with a variety of human cancers.
Patent EA-021301-B1 (EA)
Title: Pharmaceutical composition as aqueous suspension or semi-solid paste containing smectite
Inventor: HACHER BEATRICE
IPC: A61K35/02
Filed: 2011-04-29
Abstract: The present invention relates to liquid and semi-solid pharmaceutical compositions, more specifically to an aqueous pharmaceutical suspension or semi-solid paste containing natural mineral clays as active ingredients. These compositions are particularly useful for the treatment of acute and chronic diarrhea.
Patent EA-023934-B1 (EA)
Title: Process and reactor system for production of methane rich product gas
Inventor: WIX CHRISTIAN
IPC: C10L3/08
Filed: 2011-10-13
Abstract: A process is disclosed for production of a methane rich product gas comprising the steps of: (a) providing a feed comprising carbon oxide such as carbon monoxide and/or carbon dioxide, hydrogen and at least 1% C2+ hydrocarbons. (b) adding a flow comprising steam to said feed forming a reacting feed mixture, (c) reacting said reacting feed mixture in the presence of a catalyst forming a product gas rich in methane (d) withdrawing the methane rich product gas wherein the ratio of water molecules to carbon atoms in higher hydrocarbons, S/HHC, is below 25, the maximum catalyst temperature T is at least 460°C, preferably at least 480°C, and even more preferably 500°C, and the maximum catalyst temperature is less than the critical carbon formation temperature for the S/HHC value for said catalyst. In a preferred embodiment the recycle is driven by an ejector with steam feed as motive gas.
Patent EA-025729-B1 (EA)
Title: Compositions and methods for treatment of well bore tar
Inventor: LIVANEC PHILIP WAYNE
IPC: C09K8/524
Filed: 2012-12-14
Abstract: Of the many compositions and methods provided herein, one method includes contacting tar resident in a well bore with a tar stabilizer comprising an acrylonitrile-butadiene copolymer; and allowing the tar stabilizer to interact with the tar to at least partially reduce the tendency of the tar to adhere to a surface.
Patent EA-029082-B1 (EA)
Title: Equipment for separating at least one substance present in a liquid
Inventor: MARIN ADRIANO
IPC: B01J19/00
Filed: 2013-06-12
Abstract: Provided is an equipment for separating at least one substance present in a liquid, comprising a container (101, 701), arranged to internally contain a mass of said liquid (102, 702), wherein there is present an amount of said at least one substance, and heating means (103), arranged to heat said mass of said liquid (102, 702) at a temperature such as to give rise to an appreciable evaporation of said liquid (102, 702); wherein the upper part of the container (101, 701) is dome-shaped and has an opening (105) from which steam generated due to the heating of said mass of said liquid (102, 702) can escape, and wherein the perimeter wall of the container (101, 701) is internally arranged to establish an appreciable concave meniscus of said liquid (102, 702). The perimeter wall of the container (101, 701) has an internal flange (711) at said meniscus, above said meniscus, that protrudes towards the inside of the container and is preferably bent downwards, arranged such that the steam rising upwards from the meniscus is retained by said internal flange (711); wherein the steam originating from the surface of the meniscus can be kept separate from the steam originating from the flat surface of the liquid and from the steam originating from the rising bubbles of steam.
Patent EA-029721-B1 (EA)
Title: System and method for hydraulic fracturing of oil and gas reservoirs
Inventor: BREKKE KRISTIAN
IPC: E21B43/26
Filed: 2013-09-20
Abstract: The invention discloses a system and a method for hydraulic reservoir fracturing. The system may comprise a base pipe comprising a first hydraulic fracturing port, a port for insertion and accommodation of a stop ball, said stop ball being located partially in the cavity of said base pipe; a sliding device comprising a first sleeve disposed around said base pipe and having a second hydraulic fracturing port, said first sleeve having a pocket on its inner surface. Said first sleeve is movable to a first position where said pocket is located above the surface of said base pipe that does not include the port for the stop ball insertion and accommodation, which prevents said stop ball from leaving said base pipe cavity, and to a second position where said pocket is located above said stop ball insertion and accommodation port, which provides the possibility of the stop ball leaving said base pipe cavity and entering said pocket.
Patent EA-029568-B1 (EA)
Title: Biheteroaryl compounds and uses thereof
Inventor: CHEN KEVIN X
IPC: C07D403/14
Filed: 2014-04-30
Abstract: The present invention provides for compounds of Formula I-I and embodiments and salts thereof for the treatment of diseases (e.g., neurodegenerative diseases). R, R, R, X, X, A and Cy variable in Formula I-I all have the meaning as defined herein.
Patent EA-030671-B1 (EA)
Title: Preparation for treating bone lesions caused by malignant neoplasms
Inventor: IVANOVA EKATERINA ALEKSEEVNA
IPC: A61P35/00
Filed: 2016-07-20
Abstract: The present invention relates to oncology, and specifically to a novel medicinal preparation and method for treating bone lesions caused by malignant neoplasms. In order to achieve the above, a medicinal preparation is proposed which is in the form of a lyophilizate for preparing a solution for parenteral administration and includes the following ingredients: a pharmaceutically acceptable salt of a divalent metal and 1-(((((2R,3S,4S,5R)-5-(4-amino-2-oxopyrimidine-1(2H)-yl)-3,4-dihydroxytetrahydro-furan-2-yl)methoxy)(hydroxy)phosphoryloxy)(hydroxy)phosphoryl)-1-hydroxyethyl phosphonic acid or a pharmaceutically acceptable salt thereof with a molar ratio of components ranging from 1:1 to 20:1. A treatment method involves introducing a solution of the medicinal preparation according to the invention, in the form of intravenous drip infusions, with a dose of between 0.01 and 5 mg/kg of the active ingredient per 1 kg of mass of the patient, in the form of intravenous drip infusions. Treatment using the medicinal preparation according to the invention allows for reducing the metabolic activity of bone lesions caused by malignant neoplasms by up to 100%.
Patent EA-029533-B1 (EA)
Title: Brake pad for a railway vehicle (embodiments)
Inventor: VINSTROT BERND UWE
IPC: F16D69/02
Filed: 2016-01-19
Abstract: The invention is related to the field of railway transport, in particular, to brake pads for railway vehicles. A brake pad for a railway vehicle comprises a composite friction element fixed on a metal frame made in the form of a curved strip that carries on its surface a central boss with a hole for accommodation of a key and side bosses; means for mechanical fixing of the composite friction element made of an asbestos-free material; a reinforcement plate, and metal inserts. In one embodiment of the invention, the inserts are fastened to the metal frame by means of a threaded joint, and in another embodiment they are fixed on the metal frame by means of a mechanical fixture provided by cutouts hewed in the metal frame, and by curved edges of the reinforcement plate that enter the recesses made on at least one side surface of the inserts. The friction element has transverse slots made on both sides of each insert so that they are restricted on one side by side surfaces of the inserts. The inserts are disposed so that they divide the entire working surface of the pad into three parts, the length of the working surface arc of each outer part of the friction element being (0.9:1.3) of the total length of working surface arc of the friction element inner part. The total length of the working surface arc of the inserts is about 15-25% of the total length of the working surface arc of the entire friction element. The invention provides better operating reliability and wear resistance of the pad in a wide range of braking modes, and ensures stability of the working surface friction properties during the entire service life of the pad.
Patent EA-035335-B1 (EA)
Title: Methods of treating ocular disorders using varenicline
Inventor: ACKERMANN DOUGLAS MICHAEL JR
IPC: C07D487/04
Filed: 2015-10-19
Abstract: Described herein are methods and uses of pharmaceutical formulations for treating ocular disorders using varenicline.
Patent EA-031545-B1 (EA)
Title: Method for preparing double-sealed-end glycol ether
Inventor: NI YOUMING
IPC: C07C43/10
Filed: 2014-12-22
Abstract: Disclosed is a method for preparing a double end capped glycol ether, the method comprising introducing into a reactor a raw material comprising a glycol monoether and a monohydric alcohol ether, and enabling the raw material to contact and react with an acidic molecular sieve catalyst to generate a double end capped glycol ether, a reaction temperature being 50-300°C, a reaction pressure being 0.1-15 MPa, a WHSV of the glycol monoether in the raw material being 0.01-15.0 h, and a mole ratio of the monohydric alcohol ether to the glycol monoether in the raw material being 1-100:1. The method of the present invention enables a long single-pass lifespan of the catalyst and repeated regeneration, has a high yield and selectivity of a target product, low energy consumption during separation of the product, a high economic value of a by-product, and is flexible in production scale and application.
Patent EA-032763-B1 (EA)
Title: PYRAZOLO[3,4-d]PYRIMIDIN DERIVATIVE AND ITS USE FOR THE TREATMENT OF LEISHMANIASIS
Inventor: MILES TIMOTHY JAMES
IPC: A61P33/00
Filed: 2016-01-21
Abstract: The compound 3,3,3-trifluoro-N-((1,4-trans)-4-((3-((S)-2-methylmorpholino)-1H-pyrazolo[3,4-d]pyrimidin-6-yl)amino)cyclohexyl)propane-1-sulfonamide having the Formula (I) or a salt thereof, its opposite enantiomer, compositions comprising the compound and its use in the treatment or prevention of leishmaniasis, particularly visceral leishmaniasis.
Patent EA-037737-B1 (EA)
Title: Collection device for diagnostics of vaginal discharge
Inventor: NASERI SARA
IPC: G01N33/50
Filed: 2017-03-20
Abstract: A method of analyzing vaginal fluid includes collecting vaginal fluid in a vaginal fluid collecting system and transporting the collected vaginal fluid to a location for analysis. The analysis can be stored in and retrieved from a secure cloud storage data base.
Patent EA-036316-B1 (EA)
Title: Cleaning robot and method for controlling a cleaning robot
Inventor: HE HANG
IPC: A47L11/24
Filed: 2017-05-04
Abstract: A method for controlling a cleaning robot includes the following: acquiring a marked position of a charging station in a map; controlling the cleaning robot to travel to a front position of the marked position and identifying the charging station; when the charging station is not identified, generating a finding path based on the marked position; and controlling the cleaning robot to travel in accordance with the finding path and identifying the charging station in a traveling process.
Patent EA-038809-B1 (EA)
Title: Device for heating a vapour forming substance such as tobacco
Inventor: ROGAN ANDREW ROBERT JOHN
IPC: A24F40/465
Filed: 2018-05-18
Abstract: A device (1) for heating tobacco. The device comprises a compartment (2) for receiving tobacco (3). The compartment is divided into plural regions. A heater (4) is provided for heating tobacco in the compartment in use to generate vapour therefrom. The device further comprises means for controlling the heater such that a region adjacent to the heater can be selectively heated and so that vapour from that selectively heated region passes out from the device during operation of the heater. The heater (4) extends in the longitudinal direction of the compartment.
Patent EA-039660-B1 (EA)
Title: Bipyrazole derivatives as jak inhibitors
Inventor: LI YUN-LONG
Filed: 2014-05-16
Abstract: The invention relates to a solid form of 4-[3-(cyanomethyl)-3-(3',5'-dimethyl-1H,1'H-4,4'-bipyrazol-1-yl)azetidin-1-yl]-2,5-difluoro-N-[(1S)-2,2,2-trifluoro-1-methylethyl]benzamide phosphate (phosphate of compound 1) having the formulawherein the solid form is crystalline and has at least two XRPD peaks, in terms of 2-theta, selected from 6,80,2°, 16,50,2°, 20,70,2° and 23,60,2°. Said solid form inhibits the activity of Janus kinase (JAK) and is useful in the treatment of diseases related to the activity of JAK.
Patent ES-2253024-B1 (ES)
Title: Buzon publicaciones desechable y autoadhesivo.
Inventor: GONZALEZ GARCIA JOSE ALBERTO
IPC: A47G29/12
Filed: 2003-05-16
Granted: 2007-07-01
Abstract: Buzón publicaciones desechable. Consiste en un buzón de papel, cartón o plástico (1), precargado con documentación o publicaciones en pequeñas cantidades (3). Lleva un adhesivo (2) débil o cinta magnética para aplicarlo en cualquier soporte. El buzón es desechable y de fácil retirada. Resuelve el problema, tanto en coste como en estética, de la colocación de información en otro tipo de soporte permanente.
Patent ES-2237337-B1 (ES)
Title: "procedimietno y dispositivo para la realizacion de soleras en pozos circulares".
Inventor: PUITDOLLERS NOBLON JUAN-IGNACI
IPC: E21D11/38
Filed: 2004-12-21
Granted: 2006-10-01
Abstract: Procedimiento y dispositivo para la realización de soleras en pozos circulares. Procedimiento para la realización de soleras o contracúpulas en pozos circulares, caracterizado porque comprende los pasos de descenso hasta el fondo del pozo de una bolsa de un material elástico, de forma general cilíndrica o cilíndrico-cónica cerrada; inflado de la bolsa mediante la introducción en la misma de un fluido adecuado, menos denso que el hormigón, preferentemente una bentonita líquida, de tal manera que las paredes de la bolsa hagan contacto con las paredes del fondo del pozo y se adapten a las mismas; y rellenado de la bolsa con hormigón por desplazamiento del fluido con el que ha sido inflada la bolsa y dispositivo para llevar a cabo dicho procedimiento.
Patent ES-2265755-B1 (ES)
Title: Tipo de hilatura.
Inventor: PALASI MARTINEZ JORGE
IPC: D02G3/42
Filed: 2005-02-08
Granted: 2008-02-01
Abstract: Hilatura que consiste en mezclar un 95% de hilo de chenilla con un 5% de elastano. Dicha composición podrá sufrir variación en función del tipo de tejido que se quiera realizar.
Patent ES-2303400-B1 (ES)
Title: Dispositivo modular de encofrado para escalera.
Inventor: GINESTOS VERDAGUER JOSE
IPC: E04G13/06
Filed: 2005-05-30
Granted: 2009-06-02
Abstract: Dispositivo modular de encofrado para
escalera. 
     La presente invención tiene por objeto un
dispositivo modular  de encofrado para escalera que debido a su
especial  configuración permite su adaptabilidad a cualquier forma
de  escalera que se desee conformar, donde cada uno de los 
elementos modulares que componen el encofrado de la escalera, 
debido a un sistema de elevación-descenso, permiten
colocar  los módulos a la altura deseada, permiten una fácil y
rápida  instalación en obra, así como un fácil y rápido desmontaje,
y  una vez que el hormigón ha fraguado, separarlos de este para  su
posible utilización en otra escalera, donde además estos  elementos
modulares están constituidos por un reducido número  de componentes,
que unido a su fácil montaje y desmontaje  permiten disminuir en
gran manera los costes de la escalera  final.