baber/WOPTO huggingface dataset:
Patent CA-2477207-A1 (CA)
Inventor: HAACK SCOTT GRAHAM
IPC: A61N1/05
Filed: 2004-08-11
Abstract: A cardiac pacing lead for attaching a pulse generating device, such as a pacemaker or defibrillator to the heart, and a method for attaching and using the same. The cardiac pacing lead includes a passive fixation, such as tines for engaging trabecular tissue; and an active fixation, such as a helical screw, for engaging myocardial tissue. The active fixation is selectively movable between a first position where it lies within the flexible tube, and a second position where it extends at least partially from the tube at one end of the flexible tube and can be screwed into the heart tissue. The active fixation is only engaged once heart tissue with suitable conductivity properties is located by tests conducted through the electrically active tip of the active fixation. The cardiac pacing lead is secured to the patient's heart by providing an incision in the patient's body, threading the pacing lead through the circulatory system, locating suitable heart tissue by conducting tests via the active fixation, securing the passive fixation to the suitable heart tissue; securing the active fixation to the suitable heart tissue; generating an electrical pulse from a pulse generating device and passing the same through the conductor and active fixation into the patient's heart.
Patent CA-2478298-A1 (CA)
Title: Microarrays of cellulose binding chimeric proteins and methods of use thereof
Inventor: MORAG ELY
IPC: G01N33/543
Filed: 2003-03-06
Abstract: The present invention provides microarrays of proteins comprising a cellulose binding region as a means for binding to a cellulase substrate such as cellulose. The cellulose binding region may further contain biologically active exogenous moieties introduced therein while maintaining the ability to bind cellulase substrates with high affinity. In addition, methods of construction of the microarrays and using said microarrays are disclosed. The microarrays of the invention are particularly useful for displaying peptide libraries, random or rationally designed, and for high throughput screening for ligands, epitopes or ligand binding sites.
Patent CA-2478940-A1 (CA)
Title: A noise suppression system and method for phased-array based systems
Inventor: MCKERRACHER RICK
IPC: G01S7/292
Filed: 2003-03-07
Abstract: This invention relates to a system and method for suppressing external interference in radar data provided by a plurality of sensors from a main sensor array, the data being pre-processed. The noise suppression system includes a first processing module and a second processing module. The first processing module receives the radar data and produces matched radar data while the second processing module receives the radar data and produces mis-matched radar data. The system further includes a beamformer that is in communication with the first processing module and an adaptive beamformer that is in communication with the second processing module and the beamformer. The beamformer receives the matched radar data and produces beamformed matched radar data.
Patent CA-2481657-A1 (CA)
Title: Cells of which genome is modified
Inventor: SATOH MITSUO
IPC: A61P9/00
Filed: 2003-04-09
Abstract: Cells wherein the genome has been modified so that the activity of an enzyme relating to the sugar chain modification of binding the 1-position of fucose to the 6-position of a N-acetylglucosamine at the reducing end of a complex N-glycoside linked sugar chain via an .alpha.-bond is lowered, compared with the activity in the parent strain cells, or deleted; and a process for producing an antibody composition using these cells.
Patent CA-2483097-A1 (CA)
Inventor: MAZE MERVYN
IPC: A61K47/08
Filed: 2003-05-01
Abstract: L'invention concerne des méthodes de surveillance des déficits neurologiques chez des patients ayant subi une circulation extracorporelle (CPB), qui consistent à leur administrer du xénon.
Patent CA-2483143-A1 (CA)
Inventor: MEIER KEVIN C
IPC: A61B19/00
Filed: 2003-05-06
Abstract: La présente invention concerne un dispositif qui permet de mesurer la longueur d'une stomie. Un procédé d'utilisation du dispositif de mesure des stomies est également présenté.
Patent CA-2483378-A1 (CA)
Title: A digital controller for dc-dc switching converters that allows operation at ultra-high constant switching frequencies
Inventor: PRODIC ALEKSANDAR
IPC: H02M3/02
Filed: 2004-10-01
Abstract: A digital controller for low-power DC-DC switch mode power supplies (SMPS) suitable for on-chip implementation and use in portable battery-powered systems is provided. The digital controller allows operation at relatively high constant switching frequencies and can be implemented with a simple low-power digital hardware.  The digital controller includes a digital pulse width modulator (DPWM), based on a multi-bit sigma-delta (.SIGMA.-.DELTA.) principle, and a dual-sampling mode PID  compensator. The output voltage is either sampled at a frequency lower than the switching frequency (undersampled) or sampled at the switching rate. In steady-state, undersampling results in reduced power consumption, while during transients, sampling at the switching rate provides fast transient response. Another aspect of the present invention is a dual sampling/clocking scheme, which is relied on by the DPWM described. A method is also provided for controlling low power DC-DC switch mode power supplies at relatively high constant switching frequencies.
Patent CA-2487220-A1 (CA)
Title: Filling valve apparatus for a beverage filling machine
Inventor: STAVRAKIS JAMES
IPC: B67C3/26
Filed: 2004-11-10
Abstract: A filling valve apparatus for filling a container with a fluid. The apparatus includes a body portion and a stem. A sleeve is disposed over the stem and is removable from the stem and the body portion when the filling valve apparatus is serviced. A seal is mounted to the bottom of the sleeve. At least one component is movably connected to the sleeve and remains connected to the sleeve when the sleeve is removed from the stem and the body portion during the servicing of the filling valve apparatus. Similarly, a valve assembly, having a housing and a movable plunger is removable from the body portion. At least one member is mechanically connected to one of the housing and plunger for creating a unitary valve assembly that remains intact when the valve assembly is removed from the body portion during servicing of the filling valve apparatus.
Patent CA-2487734-A1 (CA)
Inventor: ANNONI GIORGIO
IPC: C12Q1/68
Filed: 2003-05-30
Abstract: Il est suggéré qu'un processus inflammatoire soit impliqué dans la pathogenèse de la maladie d'Alzheimer (AD), trouble neurodégénératif caractérisé par la présence de plaques névritiques dans le cortex cérébral, lesquelles sont composées principalement d'une petite protéine insoluble de 40-42 aminoacides (protéine amyloïde). Les corrélations biologiques de ce processus sont cependant douteuses. L'interleukine 10 (IL-10) est une cytokine qui supprime les lymphocites T et l'immunité à médiation cellulaire chez l'homme et la souris et présente de puissantes propriétés anti-inflammatoires. Afin de vérifier si la production de IL-10 est affaiblie chez des patients AD, on a stimulé le PBMC de 47 patients et de 25 témoins en bonne santé, appariés suivant l'âge, au moyen de mitogène, d'un antigène de rappel ou de peptides amyloïdes. La production de IL-2 a été mesurée dans le même environnement culturel. Les résultats ont montré que la génération de IL-10 spécifique d'amyloïde est réduite sélectivement et de manière significative chez des patients AD (p = 0,023). Des analyses effectuées sur des allèles du gène IL-10 ont révélé que le génotype associé à une production élevé de IL-10 est extrêmement rare chez des individus AD (2 % par rapport à 28%). La présence de génotypes de production faible/intermédiaire d'IL-10 (GCC/ATA ; ATA/ATA) a été associée à un âge précoce, à l'apparition de la maladie, et de (ACC/ACC ; ACC/ATA), à une vitesse accélérée de progression de la maladie. Ces données fournissent un nouvel éclairage de la biologie du processus inflammatoire impliqué dans la pathogenèse de AD, en montrant que la présence d'isoformes faiblement alléliques d'IL-10 provoque un affaiblissement, spécifique de l'amyloïde, de la production d'IL-10, et est associée à la sévérité clinique de AD. Ces résultats parlent en faveur de l'utilisation de composés anti-inflammatoires dans le traitement de cette maladie.
Patent CA-2490007-A1 (CA)
Inventor: LEONG KAM W
IPC: A61L27/52
Filed: 2003-07-18
Abstract: La présente invention concerne un système de délivrance de médicament qui comprend un hydrogel formé de cyclodextrine et d'un copolymère amphiphile renfermant un bloc de polymère A comprenant un oxyde de polyalkylène et un bloc de polymère B comprenant un polyhydroxyalcanoate, et une quantité thérapeutiquement efficace d'au moins un agent thérapeutique intimement contenu à l'intérieur de l'hydrogel. Dans un mode de réalisation préféré de l'invention, le bloc de polymère A est un oxyde de polyéthylène (PEO) et le bloc de polymère B est un poly[(R)-3-hydroxybutyrate] (PHB), et le copolymère est le copolymère tribloc ABA PEO-PHB-PEO. L'invention se rapporte également à un procédé de synthèse du copolymère tribloc amphiphile précité.
Patent CA-2490432-A1 (CA)
Inventor: DE HAAN JACOB
IPC: G01N33/86
Filed: 2004-12-16
Abstract: A cartridge for monitoring the function of a device for blood platelet diagnosis has a housing 1 which includes a test chamber 3 and a holding chamber 5. A fluid volume 7 of a test fluid 4 is present inside the holding chamber 5. An air cushion 6 is arranged above the fluid volume 7. A measurement cell 8, which has a capillary tube 9, is fitted in the upper part of the test chamber 3.
Patent CA-2490608-A1 (CA)
Inventor: BERKELEY JAMES E
IPC: A01D34/47
Filed: 2004-12-20
Abstract: A reel type mower having a mobile structure and a ground engaging traction member rotatably coupled to the mobile structure. The ground engaging traction member imparts traction movement to the mobile structure for movement on the ground at a ground speed. A power device is supported on the mobile structure and outputs a driving force to the ground engaging traction member. A bed knife is supported by the mobile structure having a cutting edge that cooperates with a grass cutting reel rotatably supported on the mobile structure. A collection apparatus is engagable with the mobile structure or removable from the mobile structure for collecting the grass clippings. A  guard device is pivotally coupled to the mobile structure and is positionable in a closed position concealing the grass cutting reel and an opened position revealing the grass cutting reel. An actuation system drives the guard device into the closed position when the collection apparatus is removed from the mobile structure and drives the guard device into the opened position when the collection apparatus is engaged with the mobile structure.
Patent CA-2492888-A1 (CA)
Title: Modification of media with common attributes on a digital nonlinear editing system
Inventor: LAIRD MICHAEL D
IPC: G11B27/034
Filed: 2000-04-14
Abstract: A system and method permitting a modification to be specified for several segments sharing a common attribute. Such shared modification may be combined with other separately specified modifications made to a composition or part of a composition. A method and system for processing a modification to be applied to sections of digital media on a digital nonlinear editing system is provided, where a first segment of a media composition represents at least a section of a digital media source. An induction of a modification to be applied to the first segment is received, and a first attribute of the first segment is identified. A first indication of the image modification is stored such that the modification is applied to other segments on the system having the first attribute in common with the first segment. A method and system for applying image modification to a first section of a digital media source on a digital nonlinear editing system also is provided, where a first segment of a media composition represents the first section. The first segment is accessed, and a first source data structure from which the first segment originates is accessed, where the first source data structure represents at least the first section of the digital media source. It is determined whether the first source data structure includes a first indication that defines a first modification to be applied to sections of the digital media source represented by segments that originate from the first source data structure. If the first source data structure includes the first indication, the first modification is applied to the first section of media represented by the first segment.
Patent CA-2494658-A1 (CA)
Inventor: ROBERTSON DAVID W
IPC: A61K9/22
Filed: 2003-08-22
Abstract: L'invention concerne l'utilisation du bupropion ou d'un sel pharmaceutiquement acceptable de celui-ci dans le traitement du syndrome des jambes sans repos chez les humains.
Patent CA-2495595-A1 (CA)
Title: Procede et appareil de congelation de produits alimentaires avec formation d'une croute superficielle
Inventor: NEWMAN MICHAEL D
IPC: F25D13/06
Filed: 2003-08-15
Abstract: La présente invention concerne un appareil et un procédé de congélation d'un produit alimentaire avec formation d'une croûte superficielle dans lesquels on utilise un corps (21) de réfrigération qui entoure et renferme une chambre (40) de congélation, ladite chambre de congélation comportant une cavité (37) dimensionnée pour contenir et s'adapter sensiblement à la forme de la surface extérieure du produit alimentaire, ladite cavité communiquant avec le corps de réfrigération; un substrat (44) de transport prévu pour transporter le produit alimentaire dans la chambre de congélation; une alimentation en liquide cryogénique; et un dispositif (33) de circulation de gaz qui est prévu à l'intérieur du corps de réfrigération et qui communique avec l'alimentation en liquide cryogénique pour introduire dans la cavité un flux de gaz (47) de refroidissement contenant du liquide cryogénique de sorte que ce dernier entre en contact avec le produit alimentaire sur sa surface extérieure.
Patent CA-2498013-A1 (CA)
Inventor: THIEBEN LAWRENCE
IPC: C08G59/56
Filed: 2003-07-01
Abstract: La présente invention concerne une composition de revêtement pigmentée, qui comprend un polymère filmogène renfermant un polymère époxyde. Le revêtement de l'invention contient un mélange d'agents de réticulation, au moins un des agents de réticulation étant un composé fonctionnel polyamide et au moins un agent de réticulation étant un composé phénalkamine. Le mélange d'agents de réticulation permet de stabiliser le pigment dans la composition de revêtement.
Patent CA-2498130-A1 (CA)
Inventor: PARK KYUSUNG
IPC: C12Q1/68
Filed: 2003-09-05
Abstract: L'invention concerne des compositions destinées à être utilisées de préférence dans la synthèse d'acides nucléiques, qui comprennent un ou plusieurs anticorps anti-transcriptase inverse (RT) et/ou un ou plusieurs anticorps anti-ADN polymérase et/ou des protéines de liaison simple brin (SSB). Certaines compositions de l'invention comprennent un ou plusieurs anticorps anti-ADN polymérase et/ou un ou plusieurs anticorps anti-RT et une ou plusieurs protéines SSB. D'autres compositions de l'invention comprennent au moins deux protéines SSB. Lesdites compositions de synthèse d'acides nucléiques peuvent également comprendre une ou plusieurs ADN polymérases, une ou plusieurs RT, un ou plusieurs nucléotides, une ou plusieurs amorces, et/ou une ou plusieurs matrices. L'invention concerne également des procédés d'utilisation desdites compositions dans la synthèse, l'amplification et le séquençage d'acides nucléiques, selon lesquels diverses combinaisons d'anticorps anti-RT, anti-ADN polymérase et protéines SSB peuvent améliorer la production et/ou l'homogénéité des produits d'extension d'amorce.
Patent CA-2498606-A1 (CA)
Inventor: GAGLIARDI IVANO
IPC: A61L15/58
Filed: 2003-09-24
Abstract: La présente invention se rapporte à une composition thermoplastique absorbant les liquides qui renferme des particules d'un matériau superabsorbant présentant des formes sensiblement dépourvues d'angles. La composition est particulièrement appropriée pour être utilisée dans des articles absorbants d'hygiène personnelle, spécifiquement dans des articles absorbants jetables, qui comprennent de préférence une ou plusieurs régions dans lesquelles ils sont transparents. Le noyau absorbant de ces articles absorbants transparents peut notamment être réalisé à partir de la composition thermoplastique absorbant les liquides selon la présente invention.
Patent CA-2500652-A1 (CA)
Inventor: BAR-OR DAVID
IPC: A01N37/18
Filed: 2003-10-02
Abstract: The present invention relates to the diagnosis and monitoring of diseases an d conditions by quantifying markers, including degradation products of disease - associated proteins, such as diketopiperazines composed of the two N-termina l amino acids or the two C-terminal amino acids of such proteins. The methods are useful for diagnosing or monitoring various diseases, including multiple sclerosis, Alzheimer~s disease and ischemia. The invention further provides binding partners specific for the markers and compositions and kits for conducting the methods of the invention.
Patent CA-2501752-A1 (CA)
Title: Compositions, organisms and methodologies employing a novel human kinase
Inventor: LIU WEI
IPC: C12N9/12
Filed: 2003-10-10
Abstract: This invention provides compositions, organisms and methodologies employing a novel human protein kinase, HPK3P23. The novel human kinase has sequence homology to the catalytic domains of several protein kinases. The gene encoding this novel protein kinase is localized in or near the 3p23 locus of the human chromosome 3.The sequence similarity between the novel human prote in and the catalytic domain of protein kinases indicates that the novel human protein may function as a protein kinase.
Patent CA-2502654-A1 (CA)
Inventor: AESCHBACHER WILLIAM EDWARD JR
IPC: E21B37/06
Filed: 2003-08-14
Abstract: A system monitors and controls the injection of additives into formation fluids recovered through a subsea well. The system includes a chemical injection unit (150) and a controller (152) positioned at a remote subsea location. The injection unit uses a pump to supply one or more selected additives from a subsea and/or remote supply unit. The controller operates t he pump to control the additive flow rate based on signals provided by sensors measuring a parameter of interest. A one mode system includes a surface facility (110) for supporting the subsea chemical injection and monitoring activities. In one embodiment, the surface facility is an offshore rig that provides power and has a chemical supply that provides additives to one or more injection units. In another embodiment, the surface facility includes a relatively stationary buoy and a mobile service vessel. When needed, the service vessel transfers additives to the chemical injection units via the buoy.
Patent CA-2503317-A1 (CA)
Title: Method of transferring gene into t cells
Inventor: HASEGAWA MAMORU
IPC: C12N15/86
Filed: 2003-10-22
Abstract: It is intended to provide a method of transferring a gene into T cells which comprises the step of contacting a paramyxovirus vector with activated T  cells. It is also intended to provide a method of producing T cells having a foreign gene transferred thereinto which comprises the step of contacting a paramyxovirus vector with activated T cells. Moreover, it is intended to provide T cells having a foreign gene transferred thereinto which are produced by the above method. Thus, a gene can be efficiently delivered specifically into activated T cells, which is expected as applicable to immunological modification strategies through T cell-directed gene delivery.
Patent CA-2504895-A1 (CA)
Title: Solid wood block
Inventor: SOUX JACQUES
IPC: E04B2/02
Filed: 2003-10-14
Abstract: The heavy wood construction block has two lumps (1) on its upper part and two flutings (2) in its lower part. Its end to end assembly is made by a false tongue housing (8). Two holes (10) are reamed in the upper part and at the two ends enabling the passage of a screw for connecting the block to the support.
Patent CA-2508895-A1 (CA)
Title: Method and system for encapsulating packets
Inventor: ROSENGARD PHILLIP I
IPC: H04L12/56
Filed: 2003-10-01
Abstract: Encapsulating packets includes receiving packets at a queue of an encapsulator. The following operations are repeated until certain criteria are satisfied. A number of packets are accumulated at the queue. A current encapsulation efficiency associated with the accumulated packets is determined. A next encapsulation efficiency associated with the accumulated packets and a predicted next packet is determined. If the current encapsulation efficiency satisfies an encapsulation efficiency threshold and if the current encapsulation efficiency is greater than the next encapsulation efficiency, the accumulated packets are encapsulated. Otherwise, the packets continue to be accumulated at the queue.
Patent CA-2511748-A1 (CA)
Inventor: BRAATEN NILS ARNE
IPC: G01F1/86
Filed: 2003-07-10
Abstract: Flow measuring method and device for measuring the velocity of a single-phase or multi-phase flow, such as a multi-phase flow in a process pipe etc. The method comprises calculating the flow velocity U only by measuring consecutive values of pressure p, temperature T and momentum D, and then calculating the change in pressure .DELTA.p, change in temperature .DELTA.T and change in momentum .DELTA.D. The device comprises a probe (1) with a housing (2) comprising electronic components connected to different sensors in the probe (1). The probe comprises a long, hollow momentum tube (3), fastened by its first end (3A) to the housing (2) and a hollow, cylindrical sensor tube (4), located inside the momentum tube (3) fastened by its first end (4A) to the first end (3A) of the momentum tube (3). The sensor tube (4) comprises plate capacitors (CA1, CA2, CA3, CA4) located on the outside of the second end (B), thereby being able to measure the conductance between the momentum tube (3) and the plate capacitors (CA1, CA2, CA3, CA4) on the sensing tube (4). The probe comprises a pressure sensor and a temperature sensor.
Patent CA-2513333-A1 (CA)
Title: Aluminium alloy with increased resistance and low quench sensitivity
Inventor: HOLLRIGL GUNTHER
IPC: C22F1/053
Filed: 2003-12-20
Abstract: The invention relates to an aluminium alloy with increased resistance and lo w quench sensitivity, said alloy containing between 4.6 and 5.2 wt. % of Zn, between 2.6 and 3.0 wt. % of Mg, between 0.1 and 0.2 wt. % of Cu, between 0. 05 and 0.2 wt. % of Zr, a maximum of 0.05 wt. % of Mn, a maximum of 0.05 wt. % of Cr, a maximum of 0.15 wt. % of Fe, a maximum of 0.15 wt. % of Si, a maximum of 0.10 wt. % of Ti, and aluminium as the remainder with impurities created during production, individually corresponding to a maximum of 0.05 wt. %, an d together a maximum of 0.15 wt. %. A preferred method for producing plates having a minimum thickness of 300 mm for producing plastic injection mouldin g moulds comprises the following steps: the alloy is continuously cast to form bars having a minimum thickness of 300 mm; the bars are heated at a maximum heating speed of 20 ~C/h between 170 and 410 ~C to a temperature of between 470 and 490 ~C; said bars are homogenised over between 10 and 14 hours at a temperature of between 470 and 490 ~C; the bars are cooled with still air to an intermediate temperature of between 400 and 410 ~C; the bars are cooled with air in motion (forced air cooling) from the intermediate temperature of between 400 and 410 ~C to a temperature of less than 100 ~C; and the bars ar e cooled to room temperature, and then thermoset. The thermoset bars can be us ed as plates for producing plastic injection moulding moulds.