baber/WOPTO huggingface dataset:
Patent PH-12015500398-A1 (PH)
Title: Ethynyl derivatives as modulators of mglur5 receptor activity
Inventor: GEORG JAESCHKE
IPC: A61P25/16
Filed: 2015-02-24
Abstract: The present invention relates to ethynyl derivatives of formula (I) wherein Y is N or CH R1 is fluoro or chloro R2 is hydrogen or methyl or to a pharmaceutically acceptable acid addition salt, to a racemic mixture, or to its corresponding enantiomer and/or optical isomer and/or stereoisomer thereof. It has now surprisingly been found that the compounds of general formula I are metabotropic glutamate receptor antagonists (negative allosteric modulators) for use in the treatment of anxiety and pain, depression, Fragile-X syndrom, autism spectrum disorders, Parkinson's disease, and gastroesophageal reflux disease (GERD).
Patent PH-12015500716-A1 (PH)
Title: N-prop-2-ynyl carboxamide derivatives and their use as trpa1 antagonists
Inventor: RIINA ARVELA
IPC: C07D209/08
Filed: 2015-03-30
Abstract: Compounds of formula I, wherein A, B, X, Z and R1-R6, are as defined in the claims, exhibit TRPA 1 activity and are thus useful as TRPA1 modulators.
Patent PH-12015501117-A1 (PH)
Title: Substrate for mounting semiconductor element and method for manufacturing said substrate
Inventor: SHIGERU HOSOMOMI
IPC: H01L23/12
Filed: 2015-05-20
Abstract: Provided is a substrate for mounting a semiconductor element, said substrate having improved adhesion between an electrode layer and a resin due to said electrode layer having roughened side surfaces and a cross-section shaped substantially like an inverted trapezoid. Also provided is a method for manufacturing said substrate, said method being characterized by containing the following steps, in this order: a) a step in which a two-layer resist layer comprising a bottom resist layer and a top resist layer is formed, from resists having different main photosensitivity wavelengths, on the surface of a metal plate; b) a step in which, with the bottom resist layer unexposed, the top resist layer is exposed using a prescribed pattern; c) a developing step in which a prescribed pattern of openings is formed in the top resist layer and the same prescribed pattern of openings is formed in the unexposed bottom resist layer, thereby partially revealing the surface of the metal plate; d) a step in which the bottom resist layer is exposed and cured; e) a step in which a prescribed plating layer is formed on the parts of the metal-plate surface revealed by the bottom resist layer; f) a step in which the entire two-layer resist layer, i.e. the bottom resist layer and the top resist layer, is removed; and g) a step in which the side surfaces of the plating layer formed in step e) are roughened.
Patent PH-12015502100-A1 (PH)
Title: Reducing the risk of autoimmune disease
Inventor: DIRK HONDMANN
IPC: A61P37/06
Filed: 2015-09-14
Abstract: The present disclosure provides a method for reducing the risk of autoimmune disease by administering a composition comprising peptides selected from a casein hydrolysate. Such a composition, may reduce the symptoms of autoimmune disease and may be a treatment for autoimmune disease, especially type 1 diabetes. Preferably, the hydrolysate consists of peptides with a molecular weight of more than 500 Da.
Patent PH-12016000243-A1 (PH)
Title: A digital odometer for distribution system design
Inventor: PANGILINAN BERNARDO A
IPC: G01B7/14
Filed: 2016-06-28
Abstract: A digital odometer has a casing, a distance wheel and a handle. The handle has a grip in the upper portion of the handle. The lower portion of the handle is fixed using a screw in the distance wheel. The casing has power supply, a LCD display, a mini speaker, keypad encoder, and microcontroller. The LCD display and keypad are mounted on the upper half-casing which are electrically connected to the power supply. The lower half-casing holds the power supply, the keypad encoder, the mini speaker and the microcontroller. The lower portion of the lower half-casing has a metallic base for support. The shaft encoder sensor is actuated holes punctured the distance wheel and electrically connected to the power supply. The keypad encoder, the mini speaker and the microcontroller are electrically connected to the power supply.
Patent PH-12016000355-A1 (PH)
Title: Use of xanthophylls for the treatment of cancers
Inventor: LU CHUEN WEI
IPC: A61P35/00
Filed: 2016-10-07
Abstract: The present invention relates to a novel use of xanthophylls, particularly astaxanthin and/or an ester thereof, for inhibiting tumor cell growth. Therefore, the present invention provides a method for preventing or treating cancers, comprising administering to a subject in need thereof a composition comprising a therapeutically effective amount of at least one type of xanthophyll.
Patent PH-12017500332-A1 (PH)
Title: Antigen binding proteins that bind cxcr3
Inventor: SWANSON BARBARA A
IPC: G01N33/566
Filed: 2017-02-22
Abstract: There is disclosed compositions and methods relating to or derived from anti- CXCR3 antibodies. More specifically, there is disclosed fully human antibodies that bind CXCR3, CXCR3-binding fragments and derivatives of such antibodies, and CXCR3-binding polypeptides comprising such fragments. Further still, there is disclosed nucleic acids encoding such antibodies, antibody fragments and derivatives and polypeptides, cells comprising such polynucleotides, methods of making such antibodies, antibody fragments and derivatives and polypeptides, and methods of using such antibodies, antibody fragments and derivatives and polypeptides, including methods of treating or diagnosing subjects having CXCR3 related disorders or conditions, including various inflammatory disorders and various cancers.
Patent PH-12017502179-A1 (PH)
Title: Substituted heterocyclyl derivatives as cdk inhibitors
Inventor: SAMAJDAR SUSANTA
IPC: A61K31/00
Filed: 2017-11-29
Abstract: The present invention provides substituted heterocyclylderivatives of formula (I), which are therapeutically useful, particularly as selective transcriptional CDK inhibitors including CDK7, CDK9, CDK12, CDK13 and CDK18, more particularly transcriptional CDK7 inhibitors. These compounds are useful in the treatment and prevention of diseases and/or disorders associated with selective transcriptional CDKs in a mammal. The present invention also provides preparation of the compounds and pharmaceutical formulations comprising at least one of the substituted heterocyclyl derivatives of formula (I) or a pharmaceutically acceptable salt or a stereoisomer thereof.
Patent PH-12018500469-A1 (PH)
Title: Sulfonamide compounds as voltage-gated sodium channel modulators
Inventor: RAMDAS VIDYA
IPC: C07D417/14
Filed: 2018-03-05
Abstract: The present invention relates to sulfonamide compounds Formula (I) wherein the substituents are as described herein, and their use in a medicine for the treatment of diseases, disorders associated with the inhibition of Voltage-gated sodium channels (VGSC) particularly NaV1.7. It further relates to the compounds herein and their pharmaceutically acceptable salts thereof, pharmaceutical compositions thereof useful in treating diseases, disorders, syndromes and/or conditions associated with the inhibition of Voltage-gated sodium channels (VGSC) particularly NaV1.7. The invention also relates to process for the preparation of the compounds of the invention. (I)
Patent PH-12018501564-A1 (PH)
Title: Lighting system
Inventor: GAWEL MAREK
IPC: F21V33/00
Filed: 2018-07-23
Abstract: The invention relates to a lighting system (1) comprising a lighting panel (2), wherein at least one light source (7), assigned to a narrow side of the lighting panel (2), is provided for coupling light into the lighting panel (2). The lighting system (1) also comprises a reflector (5) facing a flat side (8) of the lighting panel (2), wherein the flat side (8) of the lighting panel (2) facing the reflector (5) and/or the reflector (5) and/or an intermediate layer between the reflector (5) and the lighting panel (2) is provided with a surface structure (6). Said surface structure (6) is formed as a line grid made of continuous and intersecting grid lines (9). According to the invention, a high level of homogenisation of the light emission from the lighting panel (2) can be achieved in a simple manner. In this way, in particular, greater transmission losses in the edge regions of the lighting panel (2) are prevented.
Patent PH-12018501622-A1 (PH)
Title: Copanlisib biomarkers
Inventor: PENA CAROL
IPC: C12Q1/68
Filed: 2018-07-31
Abstract: This invention provides biomarkers based on the gene expression profiling which can discriminate between patients who response to and/or with longer progression free survival and patients who do not response to and/or with shorter progression free survival from copanlisib treatment in lymphoma including indolent and aggressive NHLs and CLLs. The present invention relates to the use of genes from the BCR, PI3K, NFkB, IL6, inflammation and stromal processes as predictive biomarkers for various human cancers including but not limited to NHLs.
Patent PH-12019050161-A1 (PH)
Title: A pcs type side entering stereo garage with multidimensional and intelligent transport function
Inventor: ZHOU SANYUAN
IPC: E04H6/18
Filed: 2019-08-17
Abstract: This invention discloses PCS type side entering stereo garage with multidimensional and intelligent transport function, including a main body 11; a sliding cavity 12 is arranged in the main body 11; 132 groups of garages 13 in a rectangular array are symmetrically arranged at front and rear inner walls of the sliding cavity 12; vehicle moving mechanisms 100 are arranged in the garages 13 for parking vehicles. The present invention is simple in structure, convenient in operation and maintenance, and this apparatus can automatically park vehicles in spared garages which doesn't need a manual operation and has a high efficiency. In addition, there is no potential safety problems when parking. Therefore, this apparatus has a high value of using and promotion
Patent PH-12019500042-A1 (PH)
Title: VACUUM ASSISTED SEALING PROCESSES and SYSTEMS FOR INCREASING AIR CAVITY PACKAGE MANUFACTURING RATES
Inventor: ROSS RICHARD
IPC: H01L23/36
Filed: 2019-01-04
Abstract: The present disclosure describes a sealing processes and structure for sealing air cavity electronic packages using a thermosetting, thermal plastic, other known or as yet unknown adhesives, or hybrid combinations of such adhesive(s). Processes disclosed comprise steps of providing a base and a lid, with at least one of the base and the lid having a mating surface coated with the adhesive. Initially, an air gap is maintained between the base, the lid, and the adhesive and a vacuum is generated around the base, the lid, and the adhesive.  Once the vacuum has been generated, the base and the lid are mated to create a mated package assembly with a vacuum therein. After the mating, the mated package assembly is heated to a curing temperature to cure the adhesive, and pressure may be applied as well. Because the air within the mated package assembly has been evacuated prior to heating, there is no air pressure build-up therein, reducing or eliminating the presence of blowouts and pin holes.
Patent PH-12019500445-A1 (PH)
Title: Wear-resistant rubber compositions, systems, and methods
Inventor: GOZALO FRANCISCO A
IPC: C08L15/00
Filed: 2019-02-28
Abstract: This disclosure relates to wear-resistant rubber compositions, such as those, for example, comprising at least one hydroxy-terminated polybutadiene, at least one natural rubber, at least one polymerization accelerant; at least one sulfur; and at least one polybutadiene, wherein the wear-resistant rubber composition may have an effective cross-linking density of at least about 30 x 10-5 moles/cm3.
Patent PH-12019500785-A1 (PH)
Title: Method and apparatus for anti-repackaging
Inventor: CHEN YAOGUANG
IPC: G06F21/14
Filed: 2019-04-11
Abstract: A software repackaging prevention method and device. The method comprises: operating a target file in an installation package, and loading a security dynamic library in the installation package (301); executing codes in the target file to perform the following step: acquiring digital watermark information embedded in the target file, and verification information stored in the security dynamic library (302); and verifying, according to the digital watermark information and the verification information, whether the installation package is a repackaged installation package (303). The method resolves problems of low verification efficiency, and being unable to effectively verify whether an installation package is repackaged.
Patent PH-12019501126-A1 (PH)
Title: Bispecific antibodies binding to coagulation factor ix and ciagulation factor x
Inventor: PETERS ROBERT T
IPC: C07K16/36
Filed: 2019-05-21
Abstract: The present disclosure provides antibodies that selectively binds to specific forms of clotting factors, in particular, antibodies that specifically binds to activated factor IX (FIXa) wherein the anti-FIXa antibody or an antigen binding portion thereof preferentially binds to FIXa in the presence of FIXa and factor IX zymogen (FIXz), and antibodies that specifically bind to factor X zymogen (FXz) wherein the anti-FXz antibody or antigen binding portion thereof preferentially binds to FXz in the presence of FXz and activated factor X (FXa). Also provided are bispecific molecules (e.g., antibodies) comprising, e.g., an anti-FIXa antibody or antigen binding portion thereof and/or an anti-FXz antibody or antigen binding portion thereof. The disclosure also provides compositions encoding the disclosed antibodies and bispecific molecules, vectors, cells, pharmaceutical and diagnostic compositions, kits, methods of manufacture, methods of use, and immunoconjugates.
Patent PH-12019501871-A1 (PH)
Title: Performing a change of primary node in a distributed system
Inventor: LIN PENG
IPC: H04L69/40
Filed: 2019-08-13
Abstract: A method of performing a change of a primary node in a blockchain network includes a backup node of the blockchain network determining that an epoch change needs to be performed, determining a respective weight of the backup node associated with each of three phases of a consensus process in a current epoch, determining a weight sum for the backup node based on the respective weights, sending an EPOCH_CHANGE message to the other network nodes to apply for a new primary node in a new epoch, receiving NEW_EPOCH messages from the other network nodes, determining whether a number of valid NEW_EPOCH messages exceeds a second predetermined threshold, and determining the backup node to be the new primary node in the new epoch in response to determining that the number of valid NEW_EPOCH messages exceeds the second predetermined threshold.
Patent PH-12021550084-A1 (PH)
Title: Solid forms of an azolopyrimidine compound
Inventor: JEFFREY JENNA LEIGH
IPC: A61K31/4192
Filed: 2021-01-13
Abstract: The present invention provides solid forms, solvates and hydrates of 3-[2-amino-6-(1-{[6-(2-hydroxypropan-2-yl)pyridine-2-yl]methyl}-1H-1,2,3-triazol-4-yl)pyrimidin-4-yl]-2-methylbenzonitrile, and methods of making and using the same.
Patent PH-12021550722-A1 (PH)
Title: Scotch replicas produced from individual components
Inventor: SHULMAN TAYLOR
IPC: C12G3/04
Filed: 2021-03-31
Abstract: Materials and methods for producing Scotch-like alcoholic beverages from individual components are provided herein.
Patent DE-102004004603-A1 (DE)
Title: Medical imaging patient movement compensation procedure registers first image with known calibration and compares subsequent images to determine differences for compensation
Inventor: BOESE JAN
IPC: G06T7/00
Filed: 2004-01-29
Abstract: A medical imaging patient movement compensation procedure registers the first image of a set with a 3 D data set or known calibration and uses registration of subsequent images to determine the differences and compensate the deviation. Independent claims are included for a medical C ray imaging system using the procedure.
Patent DE-102004008117-A1 (DE)
Title: Befestigungsvorrichtung für eine Gleit- oder Führungsschiene
Inventor: PABST THOMAS
IPC: E05F3/22
Filed: 2004-02-18
Abstract: Die Erfindung betrifft eine Befestigungsvorrichtung für eine Gleit- oder Führungsschiene, welche aus einem stirnseitig in das Profil der Gleit- oder Führungsschiene eingesetzten Klemmstück besteht, welches einstückig mit einer Anschlussplatte ausgebildet ist. Die Erfindung richtet sich darauf, dass das Klemmstück an wenigstens einer Außenwandung eine einer Innenwandung des Profils der Gleit- oder Führungsschiene unter Presspassung anliegende Verzahnung aufweist.
Patent DE-102004009924-A1 (DE)
Title: Picture processing method for motor vehicle, involves processing picture based on determination of real position of obstacle in vicinity of vehicle and determination of position from picture provided by camera device
Inventor: MEYER THORSTEN
IPC: G08G1/16
Filed: 2004-02-23
Abstract: The method involves determining a real position of an obstacle in the vicinity of a motor vehicle. A position of the obstacle corresponding to the real position in the actual vicinity of the motor vehicle is determined from a picture that is provided by a camera device (310).The picture is processed based on the determined positions of the obstacle. Independent claims are also included for the following: (A) a data medium characterized by a computer program with a program code for a warning device of a motor vehicle (B) a warning device for a motor vehicle.
Patent DE-102004011139-A1 (DE)
Title: Verfahren und Vorrichtung zur Körper-Klimaregelung
Inventor: KOCH JOCHIM
IPC: A41D13/002
Filed: 2004-03-08
Abstract: Eine neuartige Vorrichtung zur adaptiven individuellen Körper-Klimaregelung in Abhängigkeit von der aktuellen Körpertemperatur des Trägers (1) weist auf: DOLLAR A a) ein speziell als Weste (4) ausgebildetes Kleidungsstück mit Lüftungskanälen (2), welche an deren Ein- und Ausgang mit der Umgebung verbunden sind, DOLLAR A b) mindestens einen die Körpertemperatur des Trägers (1) des Kleidungsstücks erfassenden Temperatursensor (11, 12; 17), DOLLAR A c) ein die Lüftungskanäle (2) mit Umgebungsluft (7) beaufschlagendes Gebläse (5) und DOLLAR A d) eine Mess- und Auswerteeinheit (13), welche mit dem mindestens einen Temperatursensor (11, 12) und dem Gebläse (5) verbunden ist.
Patent DE-102004011251-A1 (DE)
Title: Verdichter, Brennkraftmaschine mit einem Verdichter und Verfahren zum Betrieb einer Brennkraftmaschine
Inventor: FINGER HELMUT
IPC: F02B37/24
Filed: 2004-03-09
Abstract: Ein Verdichter weist ein in einem Verdichtereinlasskanal drehbar gelagertes Verdichterrad und einen Zusatzkanal auf, der in Höhe des Verdichterrades in den Verdichtereinlasskanal einmündet. Über ein Stellglied ist die Gaszufuhzr in den Verdichtereinlasskanal und in den Zusatzkanal zu regulieren. Das Verdichterrad ist von einem Elektromotor antreibbar und mit einer Schwungmasse gekoppelt.
Patent DE-102004012371-A1 (DE)
Title: Adaptervorrichtung zum Prüfen von elektrischen Verbrauchern, insbesondere für oder in einem Kraftfahrzeug
Inventor: FEIERER MARIO
IPC: G01R31/74
Filed: 2004-03-13
Abstract: Adaptervorrichtung (1) zum Prüfen von elektrischen Verbrauchern, insbesondere für oder in einem Kraftfahrzeug, welche ein Gehäuse (2), mindestens eine Zuleitung (4) und Prüfspitzen (7) beinhaltet, wobei das Gehäuse (2) eine Halteeinrichtung (3, 15) zum Ankoppeln und Halten der Adaptervorrichtung (1) an einer externen Sicherung (10) aufweist.
Patent DE-102004014246-A1 (DE)
Title: Determining load-dependent supporting mechanism deformations, especially for bridges, involves applying loads in stages using multiple axle vehicles certified for normal road use with known force effects, dimensions by axle or axle group
Inventor: SCHWESINGER FRANK
IPC: G01M5/00
Filed: 2004-03-24
Abstract: The method involves introducing defined loads into the supporting mechanisms to be investigated with vehicles of known weight and geometric parameters and measuring the resulting deformations. The loads can be applied in stages using one or more multiple axle vehicles certified for normal road use and with known force effects and dimensions by axle or axle group : An independent claim is also included for an arrangement for determining load-dependent supporting mechanism deformations.
Patent DE-102004015153-A1 (DE)
Title: Verfahren zur Funktionsüberprüfung eines Pumpenmotors, insbesondere eines in eine Heizrichtung integrierten Pumpenmotors
Inventor: VEGTER DERK
IPC: F24D19/10
Filed: 2004-03-27
Abstract: Die Erfindung betrifft ein Verfahren zur Funktionsüberprüfung eines Pumpenmotors, insbesondere eines in eine Heizeinrichtung integrierten Pumpenmotors. Unmittelbar nach dem Einschalten des Pumpenmotors wird eine Ableitung eines Pumpenmotorstroms, insbesondere des zeitlichen Pumpenmotorstromverlaufs, ermittelt, wobei aus der ermittelten Ableitung des Pumpenmotorstroms geschlossen wird, ob der Pumpenmotor läuft oder blockiert ist.
Patent DE-102004016257-A1 (DE)
Title: Verfahren zum Aufwickeln eines Fadens sowie eine Aufspulmaschine
Inventor: WESTRICH HERMAN
IPC: B65H54/32
Filed: 2004-04-02
Abstract: Die Erfindung betrifft ein Verfahren zum Aufwickeln eines Fadens zu einer Kreuzspule und eine Aufspulmaschine. Hierbei wird der Faden vor Auflauf auf die Oberfläche der Spule durch ein Fadenführungsmittel oszillierend innerhalb eines Changierhubes parallel zur Spule mit einem Führungsabstand hin- und hergeführt. Um die Ablagebreite auf der Spule, in welcher der Faden abgelegt wird, zu verändern, wird erfindungsgemäß der Führungsabstand an dem Faden vergrößert oder verkleinert. Somit tritt infolge der Verschleppung eine Änderung der Ablagebreite ein. Die erfindungsgemäße Aufspulmaschine zum Aufwickeln mehrerer Fäden weist hierzu ein bewegliches Haltemittel auf, um den Abstand zwischen den Spulen und den Fadenführungsmitteln der Changiermittel zu verändern.
Patent DE-102004017186-A1 (DE)
Title: Medienregistrierungsmechanismus für eine Bilderzeugungsvorrichtung
Inventor: JEWELL ROBERT W
IPC: B41J3/60
Filed: 2004-04-07
Abstract: Bei einem Ausführungsbeispiel ist eine Bilderzeugungsvorrichtung vorgesehen, die einen Medienweg, der konfiguriert ist, um ein Druckmedium durch die Bilderzeugungsvorrichtung zu tragen, einen Ausrichtungsmechanismus, der eine Mehrzahl von Ausrichtungswänden umfaßt, und einen Bilderzeugungsmechanismus umfaßt, der konfiguriert ist, um ein Bild auf dem ausgerichteten Druckmedium zu erzeugen, das von dem Ausrichtungsmechanismus empfangen wird. Der Ausrichtungsmechanismus kann dynamisch konfigurierbar sein, um das Druckmedium gegen eine ausgewählte Ausrichtungswand von der Mehrzahl von Ausrichtungswänden auszurichten, wenn das Druckmedium entlang des Medienwegs getragen wird.
Patent DE-102004018770-A1 (DE)
Title: Scraper blade pneumatic clamp for papermaking assembly incorporates secondary expansion hose
Inventor: WOZNY ECKHARD
IPC: B05C11/04
Filed: 2004-04-17
Abstract: In a papermaking process a semi-liquid suspension of fibrous material is spread evenly over a flat moving surface by a scraper blade (22) secured within a clamp. The clamping action is effected by two inflatable hoses (14, 26). The clamp action is supported by a rubber hose (29) whose contraction distance is less than that of the second hose (28). The supplementary hose (29) can also be retro-fitted to existing machinery.
Patent DE-102004020602-A1 (DE)
Title: Plate heat exchanger for internal combustion engine, has plate gaps with another two plate gaps, which guide one of three heat exchange fluids, where fluids are exchanged with each other in adjoining gaps in respective same row sequence
Inventor: GRUENER ANDREAS
IPC: F28D9/00
Filed: 2004-04-27
Abstract: The exchanger has a plate core with heat exchange plates, and inlets and outlets for heat exchange fluids (A, B, C). Inlet and outlet channels are formed with plate gaps that communicate with one another and guide the same fluid. The gaps include another two plate gaps, which guide another fluid. The fluids (A,B,C) are exchanged with each other in adjoining gaps in respective same row sequence.