baber/WOPTO huggingface dataset:
Patent JP-2000509386-A (JP)
IPC: C07H15/10
Filed: 1997-04-30
Abstract: PCT No. PCT/SE97/00735 Sec. 371 Date Apr. 27, 1999 Sec. 102(e) Date Apr. 27, 1999 PCT Filed Apr. 30, 1997 PCT Pub. No. WO97/40838 PCT Pub. Date Nov. 6, 1997The invention refers to the use of a sulpholipid SQDG having formula (I), wherein R1 and R2, which are the same or different, are hydrogen or saturated or unsaturated, optionally hydroxy-substituted acyl groups, protonated or as a salt, for the preparation of a pharmaceutical composition for the treatment of inflammatory skin diseases or disorders, especially psoriasis. A pharmaceutical composition comprising an SQDG compound in combination with a polyunsaturated fatty acid and a therapeutically acceptable carrier is also described.
Patent JP-2001519704-A (JP)
Title: 骨成長促進内植組織
IPC: A61F2/30
Filed: 1998-04-14
Abstract: (57)【要約】
軸状の骨内植組織（１０）は、縦構造部材（１６Ａ）と、曲率制御及び支持、並びに、曲げ及び座屈に抵抗する剛性を供給する引張りケーブル（３１）とを含む。縦構造部材（１６Ａ）と引張りケーブル（３１）は、自然骨に比して実質的により大きな強度を有する複合再生骨と一体な部分になることができる。骨内植組織（１０）の柔軟性は、骨内植組織の特定の部分の構造形状を特に変えることと、移植手術前か、移植手術中か、移植手術後に、引張りケーブル（３１）の張力を調節することによって骨内植組織の剛性を調整することとによって、制御することができる。引張りケーブル（３１）は、縦構造部材（１６Ａ）に、非対称または非均一な張力を発生させるように調節することができる。
Patent JP-2001523327-A (JP)
Title: 特に軌道車両用のブレーキライニングの取付け装置
IPC: F16D65/092
Filed: 1999-02-24
Abstract: (57)【要約】
この発明は、長手方向の端部で案内部によって、好適には摩擦ライニング（３）を保持するライニングホルダ（５）のプレートによって少なくとも部分的に囲まれたライニングサポート（１）を備えてなる、特に軌道車両用のブレーキライニング取付け装置に関する。ライニングサポート（１）の前端部にはピン（７）が備えられている。前記ピンはライニングサポート（１）に対して垂直に移動可能であり、ライニングホルダ（５）がライニングサポート（１）へと押し上げられてばね付勢されると、ライニングホルダ内に設けられた開口部（９）を貫いて延び、この単一のピン（７）によってライニングホルダ（５）がライニングサポート（１）上にロックされ、これに対して移動できないようにする。ばねクリップ（１９）の形の少なくとも１つのばねがピン（７）に作用する。ばねクリップ（１９）はその固有引張力に抗してピン（７）を同伴して、隆起した解放位置へと移動可能である。このようにしてピン（７）は、ピンが解放位置にある場合には開口部（９）との嵌合状態から解放され、ライニングホルダをライニングサポートから押し外すことができる。
Patent JP-2001523352-A (JP)
Title: 投写型ディスプレイ用プリズム光ビーム・ホモジナイザー
IPC: G06Q50/10
Filed: 1998-03-27
Abstract: (57)【要約】
光源からの光線を一様化するデバイスに関する。このデバイスは、第１のマルチプリズム面と、第２のマルチプリズム面と、前記第１のマルチプリズム面と前記第２のマルチプリズム面とを接続する反射ハウジングとを含む。前記デバイスは、液晶ディスプレイ投写システムに採用してもよい。このシステムは、前記デバイスに加えて、放物形反射コリメータと、この放物形反射コリメータの中央に配置され、放物形反射コリメータにより反射された光線を放射するランプと、前記第１のマルチプリズム面と前記反射ハウジングと前記第２のマルチプリズム面とを通過した光線を受けるように配置された液晶ディスプレイとを含む。
Patent MD-20020160-A (MD)
Title: Waterproof luminaire for luminescent lamps with built-in reflector creating a directed light flux
Inventor: PARAVANTSOS ANTONIOS
IPC: F21V7/22
Filed: 2001-03-22
Abstract: The present invention relates to a waterproof luminaire for luminescent lamps with built-in catoptric or diffuse reflector, creating a directed light flux with a view of increasing the luminaire luminous efficiency. The metal bracket (3) for electric elements of the waterproof luminaire (1) is fixed into the base of the plastic box (4) so that it has small dimensions and, accordingly, it needs less material and less time for assembly compared with the metal bracket, which would be fixed in the capacity of cover onto the open upper part of the plastic box. The metal bracket (3), being fixed onto the base of the luminaire plastic box (4), creates free space in the open upper part of the plastic box (4), that allows to dispose the reflector (2) at an optimal distance from the luminescent lamps (5) in order to attain the preset concentration and direction of the light flux. The reflector (2), creating the directed light flux, is made of a thin thermoplastic film with at least one reflecting surface.Reduction of expenses for the construction of the reflector (2) and the metal bracket (3) for the electric elements as well as the fact that the reflector (2) is disposed at an optimal distance from the luminescent lamps (5) allow to simplify the assembly and to provide for the reliability of the reflector (2), creating the directed light flux into the waterproof luminaire (1), as a result of which the luminous efficiency thereof increases by 15%.Claims: 5Fig.: 4<IMAGE>
Patent MX-159651-A (MX)
Inventor: BUCKING HEINZ LUDWIG
IPC: B22D19/00
Filed: 1982-04-28
Abstract: The invention provides a method and a set-up for production of castings containing cast-in steel tubes, preferably to provide cooling elements for metallurgical furnaces. The castings are from cast steel and the steel tubes are cast-in with a superheated cast steel melt. Before the casting the tubes are filled with a granular, highly thermal conductive, refractory material. In order to assure that the cast-in steel or respectively cooling tubes remain free from leaks, the invention provides to employ as a filling material one or more of the materials: burned magnesite (sintered magnesite), corundum, sintered aluminum oxide, chromite, silicon carbide, silicon nitride.
Patent MX-155195-A (MX)
Inventor: WILKINSON RICHARD L
IPC: G11B7/258
Filed: 1980-06-11
Abstract: A video disc (11) is made by using the heat of a modulated focussed laser beam (13) as in prior proposals, but in order to get a more accurate record track, the medium on which the video disc record is made includes nitro-cellulose, or some other explosive material which is heated to its autoignition point when the heat in the focussed laser beam is above the critical level at which a pit is to be formed in the surface of the record.
Patent MX-154385-A (MX)
Inventor: BHAGWAT ANIL GOPALRAO
IPC: G03G15/00
Filed: 1983-09-20
Abstract: A sheet feeding apparatus for a copying machine includes two sheet trays (1, 2) and a frictional feeding device (3) in a fixed location for topfeeding sheets from either one of the stacks. The trays are carried one above another by a tray carriage and are arranged for independent slideable withdrawal from the tray carriage towards the front of the machine. The tray carriage is mounted for vertical movements, and the upper tray is slideably mounted on a sub-frame for movements thereover in the sheet feed direction, i.e. across the machine, so that the top sheet in either one of the two trays may be brought into feeding engagement with the feeder device.
Patent MX-160267-A (MX)
Inventor: MCHENRY ROBERT J
IPC: B65D81/18
Filed: 1984-01-03
Abstract: Methods are provided for obtaining an acceptable configuration of a thermally processed plastics container packed with food; improvements in container configuration are attained by proper container design, by maintaining a proper headspace of gases in the container during thermal processing by establishing a vacuum in the container as it is sealed and/or by controlled reforming of the bottom wall of the container. Reforming is achieved by creating an excess external pressure on the container which is sufficient to cause the bottom wall but not any portion of the sidewall to move inwardly. Further improvements are attained by controlling the thermal history of the empty container, such as by pre-shrinking the container before it is filled with food and sealed.
Patent NZ-196507-A (NZ)
Title: Method for evaporating a solution using mechanical recompression of the vapour
Inventor: EVERSDIJK B P
IPC: B01D1/28
Filed: 1981-03-16
Abstract: A liquid solution is passed through a multi-stage evaporation plant while using recirculated vapor, fed through a mechanical compressor in order to increase the pressure and temperature of the vapor. The plant comprises a number of evaporators connected in series and split up into a plurality of groups, which comprise a decreasing number of evaporators; as seen in the flow direction-the vapor being fed in parallel, streams through said groups.
Patent NZ-229175-A (NZ)
Title: High frequency induction heating of thin filaments
Inventor: SIDKY PAULETTE SHAFIK
IPC: C23C16/46
Filed: 1989-05-17
Abstract: PCT No. PCT/GB89/00505 Sec. 371 Date Dec. 27, 1990 Sec. 102(e) Date Dec. 27, 1990 PCT Filed May 11, 1989 PCT Pub. No. WO89/11770 PCT Pub. Date Nov. 30, 1989.A contactless heating apparatus for thin filaments comprises means to linearly support a length of filament (10), an induction coil (11) provided adjacent to the filament with its axis substantially parallel to the length of filament, a source (15) of alternating current in the frequency range from HF to UHF connected to the coil, and a conducting rod (16) connected to one of the end turns of the indication coil (11) and disposed substantially parallel to the length of filament (20); the arrangement being such that heating of the filament occurs adjacent to the conducting rod. The filament (20) is run through a vertical cylindrical chamber (21) in which a reducing atmosphere is maintained. The coil (11) is non-uniform in diameter, the diameter being larger at the end (14) to which the rod (16) is attached and the end (12) of the coil opposite to that to which the rod is attached is earthed (13). The rod (16) may be shaped such that the separation between rod and filament varies along the length of the rod to thereby vary the temperature profile along the heated portion of the filament. The AC power source (15) used is a Class C oscillator valve located in the induction furnace. This power source is rich in harmonics.
Patent NZ-230625-A (NZ)
Title: Pentapeptide with inhibitory effect on dna synthesis in regenerating liver and malignant hepatoma
Inventor: PAULSEN JAN ERIK
IPC: C07K7/06
Filed: 1989-09-12
Abstract: New pentapeptide with the general formula <CHEM>  wherein  Z is CH2 or CO,  Y is H or OH, and X<1>, X<2> and X<3> are each independantly OH or NH2, provided that X<2> and X<3> are not both NH2. The pentapeptide can be used as active component in compositions. The preparation of the pentapeptide is described.
Patent NZ-232687-A (NZ)
Title: 1(substituted alkyl)oxy-2-(methoxymethylidinyl or methoxyimino)carboxy methyl naphthalene methyl ester derivatives
Inventor: WENDEROTH BERND
IPC: A01N37/50
Filed: 1990-02-26
Abstract: Ortho-substituted 1-napthyl ethers of the formula   <IMAGE> (I) where X is CH or N, Y is saturated or unsaturated alkylene and R is aryl, aryloxy, arylthio or arylalkoxy, the aromatic ring being substituted or unsubstituted, and fungicides containing these compounds.
Patent NZ-239246-A (NZ)
Title: #a#1-microglobulin peptide, antibodies against it and their use in #a#1-microglobulin determination
Inventor: KOPETZKI ERHARD
IPC: C07K14/47
Filed: 1991-08-02
Abstract: A peptide according to the invention is a maximum of 40 amino acids long and contains a sequence which is at least 6 amino acids long from the amino-acid part-sequence between amino acids 144 and 183 of human  alpha 1-microglobulin and/or a sequence which is at least 6 amino acids long from the amino-acid part-sequence between amino acids 1 and 20 of human  alpha 1-microglobulin. An antibody according to the invention is able to bind specifically both to one of the peptides according to the invention and to human alpha 1-microglobulin. To determine human  alpha 1-microglobulin in a sample liquid by an immunoassay, the sample liquid is contacted simultaneously or sequentially with defined amounts of the antibody and peptide components, one of the components being labelled and the determination taking place via this label. <IMAGE>
Patent NZ-243590-A (NZ)
Title: Adaptive digital equalisation with iteration
Inventor: DESPERBEN LYDIE
IPC: H04L27/01
Filed: 1992-07-17
Abstract: The field of the invention is that of the equalising of digital signals, in particular in order to combat intersymbol interference, for example in the sphere of cellular radio communication. The invention relates to a method of equalising a digital signal, intended to combat intersymbol interference, of the type consisting in associating with each received sample (xk) an estimated symbol (Ek) representative of the transmitted symbol (Xk), the said method comprising an iterative step for suppressing intersymbol interference, each iteration consisting, for each sample (xk) of a set of received samples whose value was not determined during a preceding iteration, in:   - comparing (34) the said sample with at least one confidence threshold and, if the said sample exceeds one of the said thresholds:   - associating (36) with the said sample (xk) an estimated symbol (Ek) whose value depends on the said exceeded threshold, the value of the said sample (xk) then being determined; - suppressing (37) the intersymbol interference engendered by the said estimated symbol (Ek) in regard to the other samples belonging to the said set of received samples.   <IMAGE>
Patent NZ-265177-A (NZ)
Title: Cd8 suppressor molecules that suppress hiv-1, their detection, encoding cell lines and compositions thereof
Inventor: BOLOGNESI DANI P
IPC: C12Q1/6897
Filed: 1994-03-29
Abstract: The present invention relates to a bioactive molecule, herein referred to as the CD8 suppressor molecule, that is produced by the CD8 subset of human T-lymphocytes and suppresses type-1 human immunodeficiency virus (HIV-1) replication through inhibition of vital transcription. The invention relates to isolation of clonal CD8 cells lines that produce the antiviral activity and the development of an assay system for detection of the antiviral activity. The clonal cell lines and the assay system, described herein, may be utilized to purify, characterize and clone the CD8 suppressor molecule. The CD8 suppressor molecule may have therapeutic applications for treatment of diseases associated with HIV-1 infection.
Patent NZ-268513-A (NZ)
Title: A process for preparing a diphenylmethyl substituted piperidine derivative
Inventor: D AMBRA THOMAS E
IPC: C07D211/20
Filed: 1994-06-21
Abstract: The invention relates to compounds of the formulae I, II and IX <CHEM>  wherein     R3 is -COOH or -COOR4;   R4 is an alkyl with 1 to 6 carbon atoms; A is the substituents of its ring, each of which may be different or the same, and are selected from the group consisting of hydrogen, halogens, alkyl, hydroxy or alkoxy.   X<+> is a Lewis acid   X is halogen.   The compounds are useful as intermediates and processes for their preparation are also disclosed.
Patent NZ-310420-A (NZ)
Title: Recombinant hexose oxidase, a method of producing the same and use of such enzyme
Inventor: STOUGAARD PETER
IPC: A23L7/104
Filed: 1996-06-04
Abstract: method of producing hexose oxidase by recombinant DNA technology, recombinant hexose oxidase and the use of such enzyme, in particular in the manufacture of food products such as doughs and dairy products, animal feed, pharmaceuticals, cosmetics, dental care products and in the manufacturing of lactones are disclosed. Suitable sources of DNA coding for the enzyme are marine algal species including Chondrus crispus, Lridophycus flaccidum and Euthora cristata. In useful embodiments, the recombinant hexose oxidase is produced by Pichia pastoris.
Patent NZ-313474-A (NZ)
Title: Root cortex specific gene promoter
Inventor: CONKLING MARK A
IPC: C12N15/82
Filed: 1996-07-24
Abstract: An isolated DNA molecule which comprises a DNA promoter sequence which directs root cortex specific transcription of a downstream heterologous DNA segment in a plant cell. A DNA construct which comprises an expression cassette comprising, in the 5' to 3' direction, a promoter of the present invention and a heterologous DNA segment positioned downstream from the promoter and operatively associated therewith. Transformed plants, such as tobacco plants, comprise transformed plant cells containing a heterologous DNA construct comprising an expression cassette as described above.
Patent NZ-332315-A (NZ)
Title: Nitrone free radical trapping compounds and their use in the treatment of dementia associated with aids virus (HIV-1) infection
Inventor: FLOYD ROBERT
IPC: A61K31/167
Filed: 1997-04-17
Abstract: The used of nitrone-based free radical traps are disclosed to have activity as therapeutic and prophylactic agents in the treatment of neuronal damage associated with HIV-1 virus infection, referred to in advanced stages as dementia associated with AIDS infection or AIDS Dementia Complex (ADC).  The nitrone-based active agent is defined by the above formula wherein: X is phenyl, imidazolyl, phenothiazinyl or as defined in the specification Y is a tert-butyl group that can be hydroxylated or acetylated on one or more positions, phenyl or as described in the specification.
Patent NZ-503389-A (NZ)
Title: Vitronectin receptor antagonists comprising substituted dibenzo[a,d]cycloheptene or dibenzo[b,f]oxepine and their use as antagonists of alpha-v-beta-3 receptors or alpha-v-beta-5 receptors
Inventor: BONDINELL WILLIAM E
IPC: A61K31/47
Filed: 1998-09-18
Abstract: A compound of formula (I), wherein: A is CH2 or O; R1 is H, halo or alkyl; R2 is H, alkyl or CH2NR"R"; X is O or CH2; Y is of the formula (II), (III), (IV), (V), (VI), (VII) or (VIII); wherein G is NR", S or O; R' is H, alkyl, -Oalkyl, -Salkyl, NR"R" or halo; each R" independently is H or alkyl; and s is 0, 1 or 2. Pharmaceutical compositions comprising the compounds of formula (I) are also described. The compounds of formula are useful for the treatment of disease in which antagonism of the anb3 receptor or the anb5 receptor is indicated.
Patent NZ-504116-A (NZ)
Title: Detergent containing aqueous lye and one or more alcoholates, used for laundry or for cleaning surfaces and tableware
Inventor: STROTHOFF WERNER
IPC: C11D17/06
Filed: 1998-09-12
Abstract: The paste-form to solid, water-containing alkaline detergent contains: i) aqueous lye, preferably potash or soda lye, preferably with a concentration of 42 to 55%, in a quantity of 21 to 70% by weight and preferably 35 to 55% by weight, based on the detergent, and ii) one or more alcoholates of ethanol, propanol, isopropanol, glycerol and butyleneglycol, preferably as potassium or sodium alcoholate, in a total quantity of 0.5 to 40% by weight, preferably 1 to 10% by weight and more preferably 2 to 8% by weight (where all percentages by weight  are based on the detergent as a whole), and iii) optionally the alcohols corresponding to the alcoholate b) and/or foam inhibitors and/or builder components and/or paraffin oil and/or surfactants and/or alkali metal hydroxide in solid form. The detergent is used for cleaning surfaces and tableware or for washing laundry.
Patent NZ-509226-A (NZ)
Title: Propoxylate-containing fuel compositions for cleaning the intake system in an internal combustion engine
Inventor: GUNTHER WOLFGANG
IPC: C10L1/14
Filed: 1999-07-08
Abstract: A  fuel composition used as intake valve cleaners  for internal combustion engines comprising a main quantity of  a liquid  hydrocarbon fuel and a pure portion of at least  one propoxilate additive of formula (I) is disclosed, wherein  n is  an  integer ranging from 10 to 20, and R1  represents  a straight-chain  or branched C8-C18 alkyl radical  or  C8-C18 alkenyl  radical; optionally in combination  with  at  least one   detergent   additive   such   as,   for   example,   a polyalkylamine   of   formula  (II)   R2-NH2,   wherein   R2 represents  a  straight-chain or branched polyalkyl  radical having  a  numerical average molecular weight  ranging  from approximately 500 to approximately 5000. Also disclosed  are fuel  additive  compositions that  contain  propoxilates  of formula  (I)  and  optionally contain  additional  additives such as the polyalkylamines of formula (II).
Patent NZ-512817-A (NZ)
Title: A wrapping material comprises a cellulosic fibrous substrate coated with a clay layer and a resin coating which is printed with a aluminium ink
Inventor: OLSEN LAWRENCE JOSEPH
IPC: B32B29/04
Filed: 2001-07-05
Abstract: A wrapping material for wrapping a substance is disclosed, wherein it comprises: i) a substrate of a cellulosic fibrous material; ii) a clay layer on a side of the substrate distal to the substance to be wrapped; iii) a coating on the clay layer; iv) a continuous or discontinuous printed surface on the coating (either on the entire coating or part thereof); and comprising a resin or resin including system, and wherein the printed surface is applied in the form of an aluminium paste or an aluminium paste based ink.
Patent NZ-513449-A (NZ)
Title: Oxamic acids and derivatives as thyroid receptor ligands
Inventor: CHIANG YUAN-CHING PHOEBE
IPC: C07C235/74
Filed: 2000-02-21
Abstract: An oxamic derivative or a prodrug, isomer, or a pharmaceutically acceptable salt thereof has the formula (I) wherein: W is O, S(O)d, CH2 or NR9; R1, R2 and R3 are independently hydrogen, halogen, alkyl, trifluoromethyl, -CN, -OCF3 or -O-alkyl; R4 is as defined in the specification or R3 and R4 together form an optionally substituted carbocyclic ring A of the formula -(CH2)b- or an optionally substituted heterocyclic ring A of formula -Q-(CH2)c- or (CH2)j-Q-(CH2)k- Q is O, S or NR17; R5 is fluoro, hydroxy, alkoxy or OC(O)R9 or R4 and R5 may be taken together to form a heterocyclic ring B of formula - CR9=CR10-NH-, -N=CR9-NH-, -CR9=CH-O- or -CR9=CH-S-; R6 is hydrogen, halogen, alkyl or trifluoromethyl; R7 is hydrogen or alkyl; R8 is -OR9 or-NR19R20 and R9, R10 and R17 are as defined in the specification. The compounds are useful for treating obesity, hyperlipidemia, glaucoma, cardiac arrhythmia, skin disorders, thyroid disease, hypothyroidism, diabetes mellitus, atherosclerosis, hypertension, coronary heart disease, hypercholesteremia, depression or osteoporosis.
Patent NZ-515168-A (NZ)
Title: Polymorph of 5-[4-[2- (n-methyl-n-( 2-pyridyl)amino) ethoxy]benzyl] thiazolidine-2,4-dione, maleic acid salt
Inventor: BLACKLER PAUL DAVID JAMES
IPC: A61P/
Filed: 2000-04-19
Abstract: A polymorphic form of 5-[4-[2- (N-methyl-N-( 2- pyridyl)amino) ethoxy]benzyl] thiazolidine-2, 4-dione, maleic acid salt (the "Polymorph") characterised in that it provides: (i) an infra red spectrum containing peaks at 1763, 912, 856 and 709 cm-1; and/or (ii) a Raman spectrum containing peaks at 1762, 1284, 912 and 888 cm-1; and/or (iii) a solid-state 13C nuclear magnetic resonance spectrum containing peaks at 111.0, 113.6, 119.8, 129.1, 130.9, 131.8, 134.7, 138.7, 146.5, 152.7, 157.5, 169.5, 171.0, 178.7 ppm; and/or (iv) an X-ray powder diffraction (XRPD) pattern which gives calculated lattice spacings at 5.87, 5.30, 4.69, 4.09, 3.88, 3.61, 3.53 and 3.46 Angstroms; a process for preparing such a compound, a pharmaceutical composition containing such a compound and the use of such a compound in medicine.
Patent NZ-517982-A (NZ)
Title: Changeable camber sail on gantry rotating mast
Inventor: WARD DENNIS HAROLD
IPC: B63H9/06
Filed: 2002-03-25
Abstract: A rotating gantry mast 10 supports the sail or sails 5 and rotates with a support structure 16, 17 connected to the mast.  Attachment booms 18, 19 are pivotally mounted on the support structure at one end 20, 21 and attached to the clew or clews of the sail at the other end 8, 9.  The angles of the booms with respect to the support structure is controlled by suitably arranged control lines to assure suitable sail shape and angle of attack to the apparent wind.
Patent NZ-519465-A (NZ)
Title: A method of continuous separation of vegetable biomass into a fluid phase and a solids containing phase of pulpy consistence
Inventor: HANSEN GRAEME
IPC: A23K30/00
Filed: 2000-12-13
Abstract: Moist vegetable biomass is fed to a mixing zone equipped with stirring means of a conditioning vessel.  Aqueous juice recycled from a subsequent step is also fed to the mixing zone.  The mixture is stirred while any denser material is allowed to sink to a settling zone located below the mixing zone to eventually be disposed of.  The mixture is fed to a rotary comminutor whose operation produces a slurry that is fed to a separator for partitioning into aqueous juice and mush.  The mush is removed.  The aqueous juice is divided into major and minor portions whose ratio provides for balance between water entering and leaving the process, considering that the major portion is recycled to the mixing zone and the minor portion removed.  Preferably, the ratio is greater than about 4:1.  Preferably, the comminutor has an effective shearing gap whose width is larger than 1 mm.
Patent NZ-519747-A (NZ)
Title: Quaternary ammonium and their use as anti-tussive agent
Inventor: CHOI LEWIS SIU LEUNG
IPC: C07C217/30
Filed: 2000-12-15
Abstract: The use of a compound of formula (I) in the manufacture of a medicament for the treatment of a cough in a warm-blooded animal, wherein: J is selected from formula (II), (III), or (IV), The other substituents are as defined herein.