baber/WOPTO huggingface dataset:
Patent CA-2897334-A1 (CA)
Inventor: HUNTER JEFFREY W
IPC: A61K48/00
Filed: 2014-03-28
Abstract: The disclosure features compositions and methods for increasing the half-life of a therapeutic agent (e.g., a C5 antagonist) in the serum of a subject (e.g., a human). Also featured are compositions and methods for: (i) decreasing the frequency by which a therapeutically effective amount of a therapeutic agent must be administered to a human having, suspected of having, or at risk for developing, a medical condition for which the therapeutic agent is effective and (ii) decreasing the dosage of the therapeutic agent required for therapeutic efficacy in a human having, suspected of having, or at risk for developing, a medical condition for which the therapeutic agent is effective. The methods include reducing the serum concentration of the antigen to which the therapeutic agent binds.
Patent CA-2898021-A1 (CA)
Title: Laminate compaction using magnetic force
Inventor: CHILDRESS JAMES J
IPC: B29C43/36
Filed: 2014-01-03
Abstract: A device (40) uses magnetic force generated by a magnet to intensify compaction pressure applied to a composite laminate.
Patent CA-2898717-A1 (CA)
Title: Short bio-active peptides for promoting wound healing
Inventor: ZHANG LIJUAN
IPC: A61K38/16
Filed: 2014-01-21
Abstract: Peptides having four to six amino acid residues are disclosed that possess biological activity. These peptides constitute short fragments of the peptide HB-107 (MPKEKVFLKIEKMGRNIRN), which itself is a fragment of the antimicrobial protein cecropin B, and exhibit cell stimulatory and migratory properties. The inventive peptides comprise four to six contiguous amino acid residues located between position 11 and 16 of HB107 (MPKEKVFLKIEKMGRNIRN), namely EKMGRN. The disclosed peptides comprise a useful agent for the medical treatment of injury to the skin, such as from diabetic ulcers. The peptides also are effective in preventing and reversing skin surface damage resulting from various environmental insults. Importantly, the therapeutic effects of the peptides manifest at concentrations equal to or greater than those of peptide HB-107, and thus represent a less expensive, more versatile means for developing effective therapies. Methods for the production and use of these peptides are also disclosed.
Patent CA-2900526-A1 (CA)
Inventor: CHIRINOS JULIO A
IPC: A61K33/00
Filed: 2014-02-07
Abstract: The present invention relates to the discovery that the administration of nitrate and/or nitrite is an effective therapy for improving short-term and long-term outcomes in patients with heart failure, including heart failure with preserved ejection fraction (HFpEF). Thus, the present invention provides compositions and methods for the treatment or prevention of heart failure, including HFpEF, in a subject in need thereof.
Patent CA-2900675-A1 (CA)
Inventor: SANDLER REUBEN
IPC: A61F5/00
Filed: 2014-03-12
Abstract: An exoskeleton (100; 204; 304; 404; 504; 602; 702; 802; 902; 1002) includes a control system (120; 205; 305; 405; 505; 603; 703; 803; 903; 1003; 1010) which incorporates a feedback system used to establish and communicate orthosis operational information to a physical therapist (202, 302, 402) and/or to an exoskeleton user (109; 201; 301; 401; 501; 601; 701; 801; 901; 1001). The feedback system can take various forms, including employing sensors (704; 804; 1004; 1010) to establish a feedback ready value and communicating the value through one or more light sources (206; 306; 503; 608) which can be in close proximity to joints of the exoskeleton joints.
Patent CA-2901143-A1 (CA)
Inventor: BUDDA ELIYAHU
IPC: B23C5/10
Filed: 2014-01-16
Abstract: An end mill (10) for machining titanium includes a cutting portion (14) having blunt teeth alternated with flutes (22). Each flute (22) includes, in order from the cutting edge (30), a rake surface (28), a concavely shaped bending portion (38), a convexly shaped ejecting portion (36) and a tooth relief edge (32). The convexly shaped ejecting portion (36) has an ejection height E, which is measurable between an apex of the ejecting portion (36) to an imaginary straight line extending from a nadir of the adjacent bending portion (36) of the flute (22) to the adjacent tooth relief edge (32). In a plane perpendicular to a rotation axis (AR) of the end mill (10), the ejection height E and a cutting portion diameter DE, fulfill the condition 0.01 ODE < E < 0.031 DE.
Patent CA-2902952-A1 (CA)
Title: Vehicle-mounted inspection system
Inventor: KANG KEJUN
IPC: B60S5/00
Filed: 2015-09-01
Abstract: The present invention discloses a vehicle-mounted inspection system. The vehicle-mounted inspection system comprises: a chassis; a rotation mechanism disposed on the chassis; a first ray emission device connected to the rotation mechanism and configured to emit a ray; a first detection device connected to the rotation mechanism and configured to receive the ray emitted by the first ray emission device; and a second ray emission device connected to the rotation mechanism and configured to emit a ray. The rotation mechanism is configured to rotate the first ray emission device, the first detection device and the second ray emission device substantially around an upright axis between a retracted position and an operating position. The vehicle-mounted inspection system according to the embodiments of the present invention comprises a plurality of ray emission devices and a plurality of detection devices, which acquires transmission images of an object under inspection viewed from a plurality of angles.
Patent CA-2905318-A1 (CA)
Title: Syntonisation automatisee pour imagerie ionique a desorption/ionisation laser assistee par matrice
Inventor: BROWN JEFFERY MARK
IPC: H01J49/00
Filed: 2014-03-14
Abstract: Cette invention concerne un procédé d'imagerie ionique, comprenant les étapes consistant à : tester une première partie d'un échantillon en faisant varier automatiquement un ou plusieurs paramètres d'un dispositif à laser ou autre moyen d'ionisation et déterminer manuellement ou automatiquement à partir de ladite première partie un ou plusieurs paramètres optimaux ou préférés du dispositif à laser ou autre moyen d'ionisation. Une seconde partie de l'échantillon est par la suite analysée au moyen dudit/desdits paramètre(s) optimaux ou préférés.
Patent CA-2907039-A1 (CA)
Inventor: SOLINA BRENT A
IPC: H01M8/16
Filed: 2014-03-11
Abstract: Disclosed herein are methods, systems, and devices for generating electricity from an effluent source. In the presence of electrogenic bacteria and substrate electrodes, an electroactive biofilm is produced which possesses bioconductive capacity for efficiently producing an electric current while treating an effluent source such as, e.g., wastewater. This disclosure relates generally to the production of electricity from a biological source. In particular, this disclosure relates to microbial fuel cells (MFCs) and other bioelectrochemical systems (BES) that exploit an exogenous fuel source.
Patent CA-2907095-A1 (CA)
Title: A novel rnai molecule delivery platform based on single-sirna and shrna nanocapsules
Inventor: YAN MING
IPC: A61K9/51
Filed: 2013-03-15
Abstract: Novel siRNA and shRNA nanocapsules and delivery methods are disclosed herein. These siRNA and shRNA nanocapsules and delivery methods are highly robust and effective. This invention provides a platform for RNAi delivery with low toxicity and long intracellular half-life for practical therapeutic applications.
Patent CA-2907915-A1 (CA)
Inventor: SOSIN HOWARD
IPC: A61K39/00
Filed: 2014-04-03
Abstract: La présente invention porte, entre autres, sur des compositions de nanoparticules comprenant une pluralité de nanoparticules, chacune étant constituée d'un polymère biodégradable ou biocompatible disposé en une structure de nanoparticule délimitant une lumière interne et une surface externe et d'une préparation de composants cellulaires hydrophiles et/ou d'une préparation de composants cellulaires hydrophobes. Dans certains modes de réalisation, la préparation de composants cellulaires hydrophiles est encapsulée à l'intérieur de la lumière interne, et la préparation de composants cellulaires hydrophobes est associée à la surface externe. L'invention porte également sur divers procédés de fabrication et d'utilisation des compositions de nanoparticules selon l'invention.
Patent CA-2908848-A1 (CA)
Title: Downhole electric submersible pump with hydrodynamic bearing
Inventor: DELGADO MARQUEZ ADOLFO
IPC: H02K5/132
Filed: 2014-03-28
Abstract: An electric submersible pump is provided which has improved vibrational characteristics relative to conventional electric submersible pumps. The improved electric submersible pumps comprise an electric motor mechanically coupled to a pumping section. The improved vibrational characteristics of the electric submersible pump are attributed to the presence of one or more rotor bearings selected from the group consisting of herringbone patterned rotor bearings, pressure dam rotor bearings, circumferential groove rotor bearings, and combinations of two or more of any of the foregoing rotor bearings.
Patent CA-2910468-A1 (CA)
Inventor: SU HUAIZHI
IPC: G01M11/08
Filed: 2014-12-26
Abstract: The present invention relates to a distributed sensing optical fiber performance multi-objective multi-degree-of-freedom static and dynamic test integrated platform and a test method. In a distributed sensing optical fiber multi-objective multi-degree-of-freedom static and dynamic test device, an optical fiber multi-degree-of-freedom fixing system is sequentially connected with an artificial loading and unloading device and an oil pressure control loading and unloading device, and an optical fiber under test is connected with the optical fiber multi-degree-of-freedom fixing system and a distributed optical fiber Brillouin frequency shift acquisition system; and test on performance of optical fiber is achieved by controlling devices in the optical fiber multi-degree-of-freedom fixing system. All parts of the test platform can be freely dissembled and assembled, and in order to complete different test requirements, a multi-objective test platform is set up, which provides large secondary development space for possible test and exploration; the device of the present invention has a large number of advantages such as a simple structure, a low cost, convenient operation, less disturbance, many test classes, strong adaptability, stable performance and convenient loading and unloading.
Patent CA-2912285-A1 (CA)
Inventor: DAVIE REBECCA LOUISE
IPC: C07D471/04
Filed: 2014-05-23
Abstract: The present invention provides compounds of formula (I): compositions comprising such compounds; the use of such compounds in therapy (for example in the treatment or prevention of a disease or condition in which plasma kallikrein activity is implicated); and methods of treating patients with such compounds; wherein R5, R6, R7, A, B,W, X, Y and Z are as defined herein.
Patent CA-2912419-A1 (CA)
Inventor: POMERLEAU DANIEL
IPC: B07B1/28
Filed: 2014-03-24
Abstract: The invention relates to improvements in vacuum shakers and more specifically to the integration of multiple shaker units to a common vacuum pump system, to apparatus for controlling the airflow through shaker screens, optimization of slurry transport, and to methods of separating drilling fluid from drill cuttings.
Patent CA-2917580-A1 (CA)
Inventor: HALL LEE J
IPC: G01V1/42
Filed: 2013-08-19
Abstract: The methods described are for determining distribution, orientation and dimensions of networks of hydraulically-induced fractures within a subterranean formation containing fluids. Detectable signals are generated by particles introduced into the fractures. In an exemplary method proppant-like particles are positioned in the formation during fracturing and allowed to generate a signal during or after fracturing activity. The detectable signals generated by the proppant-like particles are used to map fracture space.
Patent CA-2918493-A1 (CA)
Inventor: LUNEBURG CATALINA MARIA
IPC: G06F19/00
Filed: 2014-08-15
Abstract: Systems and methods for generating a custom reservoir from multiple compartments representing one or more geological structures by performing custom reservoir generation on each compartment to generate one or more combined compartments.
Patent CA-2921935-A1 (CA)
Inventor: NODEHI FARD HAGHIGHI KHASHAYAR
IPC: H04L12/16
Filed: 2014-08-19
Abstract: A process/method is provided, which authenticates electronic devices allowing the installation and utilization of encryption enabling software capable of facilitating a public key infrastructure in combination with electronic devices without need for such encryption enabling software capable of facilitating a public key infrastructure to be installed at the same time as manufacture of the electronic device. The disclosed process/method may then provide a system for monitoring various metrics and statuses of the electronic devices through the manufacturing chain, distribution chain and product lifecycle.
Patent CA-2922204-A1 (CA)
Inventor: GONG HAO
IPC: H04L45/42
Filed: 2013-08-31
Abstract: The method in the embodiments of the present invention comprises: in a storage system, a switch receiving an operation request, the operation request carrying a request identifier; the switch querying a flow table of the switch according to the request identifier, so as to obtain a flow table entry matching the operation request; and the switch forwarding the operation request to a target storage device in the storage device according to a forwarding rule of the matched flow table entry, so as to use software to define characteristics of a network to process the operation request according to the forwarding rule of the flow table entry of the switch, so that the load balancing of the storage device is realized, and the information interaction between storage devices is reduced.
Patent CA-2923941-A1 (CA)
Title: Air conditioning system having actively controlled and stabilized hot gas reheat circuit
Inventor: DOWNIE JAMES PATRICK
IPC: F25B49/02
Filed: 2016-03-17
Abstract: A method for controlling an air conditioning system comprises routing refrigerant through an evaporator to cool air in a space, proportioning refrigerant flow from the evaporator between a condenser circuit and a hot gas reheat circuit that heats air leaving the evaporator, routing refrigerant flow from the condenser circuit and the hot gas reheat circuit through an expansion device and back to the evaporator, monitoring a first temperature at the evaporator, stabilizing proportioning of refrigerant flow between the condenser circuit and the hot gas reheat circuit based on the monitored first temperature.
Patent CA-2924839-A1 (CA)
Title: Calendrier en reseau sur des ordinateurs
Inventor: GAUTHIER ANDRE
IPC: G06Q10/10
Filed: 2013-09-25
Abstract: La présente invention concerne un système de calendrier qui permet à un utilisateur de créer son propre compte, de rejoindre ou d'être rattaché à une organisation à des fins d'emploi et/ou de planification, d'utiliser le compte de calendrier ou de planification hors de l'organisation, et de conserver au moins une partie de la base de données de calendrier une fois les liens avec l'organisation rompus. Des modes de réalisation de la présente invention permettent à un utilisateur d'indiquer différemment sa disponibilité de travail ou de participation pour les diverses organisations auquel l'utilisateur appartient.
Patent CA-2926488-A1 (CA)
Inventor: HAZEL WILLIAM
IPC: E02B15/04
Filed: 2016-04-11
Abstract: Apparatus for recovering spilled oil in water infested with floating ice or other debris comprises a fence having an upper rail and lower rail encircling an area to receive an oil skimmer. A plurality of buoyancy units maintain the fence at an appropriate water level. An ice-deflecting cone covers the bottom of the fence when the apparatus is deployed. A plurality of cables may be attached to the upper rail of the fence to raise and lower the apparatus into the water. The fence is preferably circular, with a diameter in the range of 10 to 50 feet. The fence preferably includes a plurality of spaced-apart vertical supports between the upper and lower rails to keep chunks of ice or other debris from entering into the encircled area, and the lower barrier structure is perforated, with openings in the range of less than an inch to several inches.
Patent CA-2926522-A1 (CA)
Title: Catalyst system for polymerizing olefinic monomers
Inventor: BERTHOUD ALEXANDRA
IPC: C08F210/16
Filed: 2014-10-07
Abstract: A catalyst system comprising: a) a metal complex of the formula CyLMZp, wherein M is a group 4 metal Z is an anionic ligand, p is number of 1 to 2, preferably 2 Cy is a cyclopentadienyl-type ligand and, L is a ligand of the formula (A) wherein each A is independently selected from the group consisting of nitrogen and phosphorus and R1, R2, R3 and R4 are independently selected from the group consisting of hydrogen, unsubstituted or substituted hydrocarbyl, unsubstituted or substituted silyl and unsubstituted or substituted germyl residues, and b) a boron containing activator, characterized in that the molar ratio of the boron of the activator to M of the metal complex is greater than 2.5.
Patent CA-2927012-A1 (CA)
Title: Method of treating conditions of the eye with an anti-vegf darpin
Inventor: HOHMAN THOMAS
IPC: A61K47/48
Filed: 2014-11-04
Abstract: Disclosed herein are methods for the treatment of a patient having an exudative age-related macular degeneration and other conditions of the retina by administering a binding protein comprising an ankyrin repeat domain, wherein the binding protein is first administered in 2 to 5 doses, with an interval of 25 to 35 days between each dose, and then is administered in additional doses with a longer interval between doses.
Patent CA-2927100-A1 (CA)
Title: Air dispersion of mineral fibers in ceiling tile manufacture
Inventor: BROWN MARTIN W
IPC: D21B1/06
Filed: 2014-10-14
Abstract: A method of forming a dilute water slurry for water felting a basemat for an acoustical ceiling tile comprising delivering a bale of compressed mineral wool with a density of at least 8 lbs. per cubic foot at an unbaling station, releasing a binding holding the bale in compression, mechanically separating the fibers of a mineral wool bale with mechanical instrumentalities arranged to disperse the fibers to a generally uniform density of less than 2 lbs. per cubic foot prior to passage of the fibers through the tank inlet, and causing the separated mineral fibers to pass into the mixing tank for contact with water suspended binder.
Patent CA-2927329-A1 (CA)
Title: Method for the production of beverages by means of capsules
Inventor: RAPPARINI GINO
IPC: A47J31/36
Filed: 2014-10-17
Abstract: A method is provided for the production of beverages by means of a capsule comprising a side wall (5), an entry surface (6) for the entrance of water under pressure into the capsule (1), the side wall (5) and the entry surface (6) forming the containment volume (V) for containing the infusion or soluble product (P), and the entry surface (6) comprising one or more reduced thickness areas (3), wherein the method comprises the following steps: pushing the entry surface (6) of the capsule (1) using pushing means (S) and injecting a flux of water under pressure so as to open the one or more reduced thickness areas (3) of the entry surface (6) so as to allow the water under pressure to enter the capsule (1).
Patent CA-2927447-A1 (CA)
Title: Three-dimensional virtual environment
Inventor: ROGERS JOSEPH D
IPC: G06F3/048
Filed: 2013-10-23
Abstract: Systems and methods of rendering a three-dimensional virtual environment rendering are disclosed. The system comprises a central processing device, a plurality of user devices in data communication with the central processing device, a plurality of application servers in data communication with the central processing device, and software executing on the central processor. The software creates and renders a 3D virtual environment, receives user data from each of the plurality of user devices, renders the user data received from each of the user devices in the 3D virtual environment, receives application data from each of the application servers, renders the application data received from each of the application servers in the 3D virtual environment, and outputs the rendered 3D virtual environment to each of the user devices. The 3D virtual environment serves as a direct user interface with the Internet by allowing users to visually navigate the world wide web.
Patent CA-2928570-A1 (CA)
Title: Improved methods and systems for jacket joints
Inventor: ROBERTS JAMES MARTIN
IPC: F16L3/00
Filed: 2014-09-17
Abstract: A system comprising a protective jacket for insulating pipe is provided. The protective jacket comprises a first metal shell comprising an interior surface and an exterior surface, wherein the interior surface comprises a moisture protective coating, and the exterior surface comprises a film adhered to the exterior surface by an adhesive, and wherein the adhesive provides for a toolless removal of the film.
Patent CA-2929675-A1 (CA)
Title: Composition for weight management
Inventor: O'HARA STEPHEN PATRICK
IPC: A23L33/00
Filed: 2014-11-05
Abstract: The present invention relates to compositions for weight management comprising: a) a microbiome modifying component; b) a satiety modifying component; and c) a metabolic modifying component. The composition may also be used for the treatment of obesity, elevated cholesterol, diabetes, hypertension or heart disease.
Patent CA-2930472-A1 (CA)
Title: Systeme d'aeration pour turbine hydraulique
Inventor: BEAULIEU SEBASTIEN
IPC: F03B3/12
Filed: 2014-10-28
Abstract: L'invention porte sur un système d'aération (100) pour la roue mobile (10) d'une turbine hydraulique, la roue mobile (10) comprenant une pluralité de pales (2), de telle sorte que des canaux entre pales (11) sont conçus entre chaque paire de pales (2) pour l'admission d'air dans l'écoulement d'eau circulant à travers la turbine hydraulique, de telle sorte que le système d'aération (100) comprend au moins un profil hydraulique (12) situé dans le canal entre pales (11) de la roue mobile (10) venant en contact avec la paire de pales (2) constituant le canal entre pales (11) où est situé le profil hydraulique (12), de telle sorte que le profil hydraulique (12) a un profil symétrique non axial, et de telle sorte qu'au moins l'une des pales (2) en contact avec le profil hydraulique (12) comprend un canal d'aération (20) fournissant de l'air au profil hydraulique (12).
Patent CA-2930581-A1 (CA)
Title: Composes pour la tomographie par emission de positrons
Inventor: VLAHOV IONTCHO R
IPC: A61K51/04
Filed: 2014-11-13
Abstract: L'invention concerne des composés, des compositions et des méthodes pour diagnostiquer et/ou surveiller une maladie pathogène au moyen de la tomographie par émission de positrons. L'invention porte également sur des conjugués de formule B-L-P dans lesquels B représente un radical d'un agent de ciblage sélectionné parmi les ligands de liaison au récepteur de vitamine (comme le folate), les ligands de liaison PSMA ou les inhibiteurs PSMA; L représente un liant divalent comprenant l'acide aspartique, la lysine ou l'arginine, et P représente un radical d'un agent d'imagerie ou agent de radiothérapie, tel qu'un radionucléide ou un groupe contenant un radionucléide ou un radical d'un composé capable de se lier à un radionucléide, tel qu'un groupe chélateur métallique.
Patent CA-2930974-A1 (CA)
Inventor: MCNEILLY CECIL
IPC: F16G15/00
Filed: 2014-11-18
Abstract: An anchor point for a lever binder is disclosed herein. The anchor point includes a collar. The anchor point also includes a cap including a base and at least one arm. The collar and the cap cooperate to form an aperture for receiving a handle of a lever binder.