baber/WOPTO huggingface dataset:
Patent NO-1996016-I1 (NO)
IPC: C07K14/535
Filed: 1996-12-18
Abstract: A method for preparing and isolating a transformation vector containing CSF/cDNA is described. The method comprises:  preparing RNA from a cell that produces CSF;  preparing polyadenylated messenger RNA from said RNA;  preparing single stranded cDNA from said messenger RNA;  converting the single stranded cDNA to double stranded cDNA; inserting the double stranded cDNA into transformation vectors and transforming bacteria with said vector to form colonies; picking pools of 200 to 500 colonies each and isolating plasmid DNA from each pool; transfecting the plasmid DNA into suitable host cells for expressing CSF protein; culturing the transfected cells and assaying the supernatant for CSF activity; and selecting CSF positive pools and screening the colonies used to make the pool to identify a colony having CSF activity. Also described are a cDNA coding for a protein having CSF activity (i.e. CSF/cDNA), a microorganism or cell line transformed with a recombinant vector containing such CSF/cDNA, and a method for producing CSF protein by expressing said CSF/cDNA by culturing a microorganism or cell line. The invention also provides a method of purifying the CSF proteins and the purified proteins so produced.
Patent LU-92154-I2 (LU)
IPC: C07D409/14
Filed: 2013-02-20
Abstract: Indazole compounds that modulate and/or inhibit the activity of certain protein kinases are described. These compounds and pharmaceutical compositions containing them are capable of mediating tyrosine kinase signal transduction and thereby modulate and/or inhibit unwanted cell proliferation. The invention is also directed to the therapeutic or prophylactic use of pharmaceutical compositions containing such compounds, and to methods of treating cancer and other disease states associated with unwanted angiogenesis and/or cellular proliferation, such as diabetic retinopathy, neovascular glaucoma, rheumatoid arthritis, and psoriasis, by administering effective amounts of such compounds.
Patent NL-301031-I2 (NL)
IPC: A61K31/33
Filed: 2020-01-22
Abstract: Methods to elevate progenitor and stem cell counts in animal subjects using compounds which bind to the chemokine receptor CXCR4 are disclosed. Preferred embodiments of such compounds are of the formula Z-linker-Z' (1) or pharmaceutically acceptable salt thereof wherein Z is a cyclic polyamine containing 9-32 ring members of which 3-8 are nitrogen atoms, said nitrogen atoms separated from each other by at least 2 carbon atoms, and wherein said heterocycle may optionally contain additional heteroatoms besides nitrogen and/or may be fused to an additional ring system; or Z is of formula (a), wherein A comprises a monocyclic or bicyclic fused ring system containing at least one N and B is H or an organic moiety of 1-20 atoms, Z' may be embodied in a form as defined by Z above, or alternatively may be of the formula -N(R)-(CR<sub>2</sub>)<sub>n</sub>-X wherein each R is independently H or straight, branched or cyclic alkyl (1-6C), n is 1 or 2, and X is an aromatic ring, including heteroaromatic rings, or is a mercaptan; "linker" represents a bond, alkylene (1-6C) or may comprise aryl, fused aryl, oxygen atoms contained in an alkylene chain, or may contain keto groups or nitrogen or sulphur atoms.
Patent ES-2514965-R1 (ES)
Title: Tubo de recirculación de gas de un motor de combustión y método para fabricar dicho tubo
Inventor: AZPIAZU ECHAVE IÑAKI
IPC: F16L59/00
Filed: 2013-04-25
Abstract: Tubo (1) de recirculación de gas de un motor de combustión que comprende un conducto (2) que es apto para que por su interior circule dicho gas. El conducto (2) comprende una superficie externa (3) que está cubierta al menos parcialmente por un material aislante (4) para aislar térmicamente el tubo (1) de recirculación. Dicho material aislante (4) está sobremoldeado sobre dicho conducto (2). El método para fabricar dicho tubo (1) de recirculación de gas comprende una etapa inicial en donde el conducto (2) es introducido en la cavidad de un molde, una etapa de mezclado en donde una base y un reactivo son mezclados, una etapa de llenado en donde dicha mezcla es conducida a la cavidad del molde, y una etapa de curado y extracción en donde el tubo (1) es extraído de la cavidad del molde tras el tiempo de curado.
Patent CL-2008002259-S1 (CL)
Title: Aparato para diagnostico de cuerpo tronco conico con casquete esferico superior; presenta rebaje aplanado eliptico frontal, con resalte perimetral biselado y abertura central; el sector superior posterior posee una depresion circular con puente cruzado y resaltes cilindricos verticales inferiores sobre planos triangulares esquinados.
Inventor: KRISHNAN SRINIVASAN
Filed: 2008-07-31
Abstract: Aparato de diagnóstico.
Patent CL-2010000507-S1 (CL)
Title: Dispositivo conector para cables formado por dos cilindros apaisados, uno sobre el otro, unidos por zona cóncava inclinada; al frente posee rebaje cilíndrico superior con facetas, y arista resaltada convexa inferior con abertura, bajo la cual hay un sector rectangular vertical rehundido con cara opuesta idéntica e invertida a esta.
Inventor: GIEMZA LEE MARK
Filed: 2010-05-18
Abstract: Dispositivo conectador para cables.
Patent HN-2012002056-S1 (HN)
Title: Paquete blister en forma de concha teniendo los blister recibidos en el mismo
Inventor: NANCY GAIL LIMBACK
Filed: 2012-09-28
Abstract: LA FIGURA 1 ES UNA VISTA EN PERSPECTIVA DE UN PAQUETE BLISTER EN FORMA DE CONCHA TENIENDO LOS BLISTER RECIBIDOS EN EL MISMO QUE DEMUESTRA EL NUEVO DISEÑO FIGURA 2. ES UNA VISTA FRONTAL DEL MISMO. FIGURA 3 ES UNA VISTA TRASERA DEL MISMO FIGURA 4 ES UNA VISTA LATERAL IZQUIERDO DEL MISMO FIGURA 5 ES UNA VISTA LATERAL DERECHO DEL MISMO. FIGURA 6 ES UNA VISTA POR ARRIBA DEL MISMO Y FIGURA 7 ES UNA VISTA POR DEBAJO DEL MISMO.
Patent SI-0669204-T1 (SI)
Title: A self-adhesive label for resealable packaging
Inventor: PEDRINI MAURIZIO
IPC: G09F3/10
Filed: 1995-02-08
Abstract: A self-adhesive label (6) for resealable packaging (1) which is both simple and cheap to manufacture and a method for its production are described, the label (6) including a structurally independent tongue (10) which is removably attached to a limited area of the self-adhesive surface (8) including a portion of edge (9) and which can be gripped for its easy removal. <IMAGE>
Patent SI-1007686-T1 (SI)
Title: Tuberculosis vaccine
Inventor: KAUFMANN STEFAN H E
IPC: C07K14/35
Filed: 1998-08-12
Abstract: The present invention relates to novel recombinant vaccines providing protective immunity against tuberculosis. Further, the present invention refers to novel recombinant nucleic acid molecules, vectors containing said nucleic acid molecules, cells transformed with said nucleic acid molecules and polypeptides encoded by said nucleic acid molecules.
Patent TR-199701190-T1 (TR)
Inventor: MARTORELL MR IGNACIO FERNANDEZ
IPC: A01M1/20
Filed: 1997-02-19
Abstract: Kokulu, dezenfektan ve böcek öldürücü buhar ve koku yayan tabletler için gelistirilmis destekli kutu. Adi geçen tasiyici kabin gövdesi (1) boylamasina ve paralel açikliklara (5) sahiptir ve bunlar ne kutunun (1) üst kenarina (4) uzanmaz ne de kutunun alt kenarina (3) uzanmaz ve çentik açikliklari (7) vardir. Dahili çitçit seklindeki çengeller (11) kapaktan (8) asagiya dogru sarkar ve açikliklara (7) girerek kilitlenir.
Patent TR-199701478-T1 (TR)
Inventor: HINKE V THOMAS
IPC: B01D53/34
Filed: 1996-05-29
Abstract: A system and method for the reduction of NOx in a flue gas are disclosed. A P4 in water liquid/liquid emulsion is injected into a flue gas having a temperature of about 180 DEG  C. to about 280 DEG  C. to induce phosphorus-accelerated oxidation of the NO in the flue gas. NO2 and phosphorus oxides are subsequently removed from the flue gas stream at a location sufficiently downstream of the injection site that the oxidation of NO in the flue gas is substantially complete prior to the removal of NO2. This significantly improves the NOx recovery rate of the present system and method over those of the prior art. The system can be retrofitted to the waste gas stream of any stationary combustion source regardless of the fuel burned. The system is advantageously used in connection with a wet scrubber for the removal of NO2 and other water soluble flue gas components. Injection of the emulsion results in the creation of ozone by means of the controlled oxidation of white phosphorus. The ozone reacts with nitrogen oxide (NO), which generally accounts for 90% of flue gas NOx, to produce nitrogen dioxide (NO2). The reaction products (NO2 and the P4O10,) can be removed from the flue gas together with SO2 and particulates in the wet scrubber wherein they are efficiently transferred from the gaseous phase to the buffered scrubbing liquid. In the scrubber, the temperature gradient is preferably set through the dew point, so that it recovers both latent as well as sensible heat energy from the flue gas which energy can be sold to commercial or residential consumers to recover at least a part of the capital costs (purchase and operation) associated with the system.
Patent AT-E340618-T1 (AT)
Inventor: FLECK UTE
IPC: B01J20/30
Filed: 2000-01-20
Granted: 2006-10-15
Abstract: The invention relates to a process for preparing a highly loaded adsorbent, which process comprises the steps of   a) extracting an oil from an oil crude product by means of supercritical fluid extraction thus, obtaining a loaded supercritical fluid (SCF); b) expanding the loaded SCF of step a) followed by heating to obtain a liquid phase and a in-loading reduced SCF phase; c) optionally decreasing the pressure and/ or raising the temperature of the SCF phase of step b) to conditions of adsorption; d) introducing the SCF of step b) or step c) into a fixed bed adsorber to obtain an adsorbent loaded with the purified oil and pure SCF; e) feeding the liquid phase of step b) as a reflux to the extraction device of step a) ; f) compressing and tempering the pure SCF of step d) to extraction conditions;   g) recycling the pure SCF to the extraction device of step a).   The invention further comprises a process for purifying an oil from an oil crude product by desorbing the adsorbed oil. The invention further comprises 16 A process for purifying an oil, optionally combined with a process for preparing a highly loaded adsorbent, which process comprises the steps of:   A) extracting a fraction containing the oil together with high volatile components from a crude synthetic or natural oil mixture by means of supercritical fluid extraction (SFE) thus, obtaining a loaded supercritical fluid (SCF) and a raffinate containing the low volatile components of the crude product; B) expanding the loaded SCF of step A) followed by heating to obtain a liquid phase containing the oil and high volatile components and an unloaded gas phase (step B-1) or to obtain an in-loading reduced SCF and a liquid phase (step B-2); C) optionally decreasing the pressure and/ or raising the temperature of the in-loading reduced SCF phase of step B-2) to conditions of adsorption; D) optionally introducing the in-loading reduced SCF of step B-2) or of step C) into a fixed bed adsorber to obtain an unloaded gas phase and an adsorbent loaded with oil; E) collecting the unloaded gas phase of step B-1) or of step D) in a vessel and controlling the content of the gas components; F) optionally feeding pure gas into the vessel of step E) to guarantee the same gas composition over the whole process time; G) feeding part of the liquid phase of step B-1) or all of the liquid phase of step B-2) at the same temperature and pressure of the column as a reflux to the extraction device of step A); H) pressurizing the gas phase of step E) or of step F) followed by cooling to separation conditions; I) recycling the SCF of step H to the extraction device of step A);   J) optionally feeding the liquid phase of step B-1) to a second extraction device; K) extracting a fraction of high volatile components from the extract of step B-1) by means of SFE thus obtaining a loaded SCF and the pure oil as raffinate; L) treating the reflux and the SCF as described in the steps B-1 - I); M) collecting the oil at the bottom of the column as a raffinate.
Patent AT-E330149-T1 (AT)
Inventor: HOERMANN MICHAEL
IPC: F16H1/16
Filed: 2000-09-15
Granted: 2006-07-15
Abstract: The screw drive has a supporting wheel (7) for support of the worm shaft (2) on the opposite side of the worm wheel (5). The worm wheel is in meshed contact with the worm shaft and is at the same height as the support wheel in the longitudinal direction on the worm shaft. A drive motor (1) is attached to the worm shaft for driving the system.
Patent AT-E292572-T1 (AT)
Inventor: STEINMANN MARKUS
IPC: B61L5/00
Filed: 2000-10-05
Granted: 2005-04-15
Abstract: The device has a drive rod and cam rods (5) connected to switch blades. The rods are positively locked together by locking elements (13,11), and are relatively moveable within a pattern when the locking elements are released. The cam rods are coupled to a central working flange (2). The flange and a working part (1) on the drive rod are relatively moveable within a first pattern, and positively locked via the locking elements. The drive rod is connected to the working part via a bearing pin (11). A second pattern is formed by two bores (9,10), through which the bolt is inserted.
Patent AT-E249948-T1 (AT)
Inventor: STUBBE INGOLF
IPC: B60P7/15
Filed: 2000-12-13
Granted: 2003-10-15
Abstract: The freight securing device is in the form of a beam with connected, preferably and extruded hollow bean with hook connectors on both ends and movable clamping webs. A push-in body (28) of the clamping element (26) carrying the clamping web can be inserted into the end of the beam, in the cavity of which it can move.
Patent AT-E333517-T1 (AT)
Inventor: HALLING KEVIN C
IPC: C12N15/09
Filed: 2000-03-03
Granted: 2006-08-15
Abstract: Methods for detecting cancer that include hybridizing a set of chromosomal probes to a biological sample obtained from a patient, and identifying if aneusomic cells are present in a selected subset of cells obtained from the biological sample are described. A set of chromosomal probes and kits for detecting cancer that include sets of chromosomal probes, are also described.
Patent AT-E342772-T1 (AT)
Inventor: IMHOF RAINER DR
IPC: B03D1/14
Filed: 2000-08-31
Granted: 2006-11-15
Abstract: A separating device (10) especially for use in a pneumatic flotation system comprises an annular channel (18), at least one nozzle (16) for introducing aerated pulp substantially horizontally and tangentially into the annular channel (18), froth extraction means (26) for the removal of separated froth from the annular channel (18), and pulp extraction means (24) for the removal of separated pulp from the annular channel (18), the at least one nozzle (16) being configured so that the aerated pulp introduced into the annular channel (18) rotates therein with centrifugal forces of between 5 and 20 ms<-2>.  <IMAGE>
Patent AT-E401640-T1 (AT)
Inventor: VENZANT KENNETH
IPC: G08B17/107
Filed: 2000-01-12
Granted: 2008-08-15
Abstract: Smoke alarms that incorporate dust repelling screens exhibit improved performance with fewer false alarms. Effective screens include conductive strands combined with non-conductive elements.
Patent AT-E246711-T1 (AT)
Inventor: POLICELLO GEORGE A
IPC: A01N25/30
Filed: 2000-02-16
Granted: 2003-08-15
Abstract: The present invention teaches heterocyclic amine modified siloxanes and their use, a preferred of which is as adjuvants for pesticides. The heterocyclic amine modified siloxanes have siloxane backbones with pendant, terminal or intermediate heterocyclic amine groups, which may contain one or more heteroatoms, i.e., nitrogen, sulfur or oxygen. The heterocyclic amine groups or the siloxane may be functionalized further with alkyl or alkyleneoxide groups.
Patent AT-E254091-T1 (AT)
Inventor: COSTA FULVIO
IPC: G02B6/00
Filed: 2000-03-08
Granted: 2003-11-15
Abstract: A sol-gel process is described that allows dry gels to be produced, and where necessary, the corresponding dense vitreous bodies, around an incompressible insert. A particular feature of the process is the step of rotating a container holding the sol and incompressible insert throughout the gelling step under such conditions that a wet gel adhering to the insert is produced, which is then dried. The process is useful particularly for the production of preforms for optical fibers, which are also claimed.
Patent AT-E271515-T1 (AT)
Inventor: BEHLE FRITZ
IPC: B66B29/06
Filed: 2000-03-03
Granted: 2004-08-15
Abstract: The invention relates to a profile for comb supports of escalators and moving walkways comprising a plurality of segments for being connected to a comb support, the segments having respective front faces juxtaposed to one another, wherein the front face of a first segment of the plurality of segments comprises a nose shaped projection and the front face of a second segment of the plurality of segments comprises a groove for receiving said projection of the first segment, forming a tongue and groove arrangement for releasably interlinking the segments outside of the comb support.
Patent AT-E386997-T1 (AT)
Inventor: O'CONNOR MICHAEL
IPC: G08G1/123
Filed: 2000-05-12
Granted: 2008-03-15
Abstract: A host system (2) receives uploaded real time bus progress data (20) for bus systems (13). This is determined by the bus system (13) detecting a beacon short range radiation signal from a bus stop systems (11). Uploads are only made if the bus is not running according to the timetable. The host system (2) downloads bus status data (21) for remaining stops (12) on the route. The host system (2) also downloads advertising content to both the bus stop systems (11) and the bus systems (13). This is intelligently processed to select that which is applicable.
Patent AT-E232418-T1 (AT)
Inventor: KOWALLIS REID BURTON
IPC: G01N35/02
Filed: 2000-05-25
Granted: 2003-02-15
Abstract: Generally, the present invention provides a device and method for accurately locating a multi-well plate at a plate-support location, e.g., a work surface, of an automated laboratory machine, such that one or more acting members of the machine, such as an array of pipette tips, optical sensors, or the like, can accurately address and operate on the individual wells. Interior and/or exterior surface regions of one or more wells of a multi-well plate are used as the primary plate features engaged by locating structure of the machine. In one particular embodiment one or more upwardly tapered projections extend from a plate-support surface of a plate-handling machine for mating engagement with the exterior surface regions of one or more wells. In another embodiment, the exterior surface regions along one or more well bottoms are engagingly received within bores, or other receiving structure, formed on the plate-support surface of a machine. In a further embodiment, one or more downwardly extending projections depend from an acting-member support, along with the acting members of a machine. Introduction of the projections into some of the wells of a multi-well plate serves to align the acting members with the plate's other wells. A biasing assembly can be used to press together the engaging surface regions of the wells and the locating structures of the machine.
Patent AT-E267532-T1 (AT)
Inventor: ROSEN HENRI E
IPC: A43B17/00
Filed: 2000-06-14
Granted: 2004-06-15
Abstract: A shoe bottom assembly is described in which the transverse angle of the foot-supporting surface is manually adjustable.
Patent AT-E233937-T1 (AT)
Inventor: BILL COLIN
IPC: G11C16/06
Filed: 2000-08-01
Granted: 2003-03-15
Abstract: A method of and a flash memory device for quenching bitline leakage current during programming and over-erase correction operations. The flash memory cells are organized in an array of I/O blocks with each block having columns and rows. An array of resistors is connected between the common array source connection and ground. The array of resistors is made up of sets of resistors, each set having a programming mode resistor and an APDE mode resistor. A data buffer switches either a programming mode resistor or APDE mode resistor into the circuit when a bitline is selected for either programming or APDE. The values of the resistors are selected to raise the voltage at the source above a selected threshold voltage of the memory cells so that over-erased cells will not provide leakage current to the bitline during either programming or APDE.
Patent AT-E265241-T1 (AT)
Inventor: FRANCIS RALPH T
IPC: A61L27/00
Filed: 2000-09-14
Granted: 2004-05-15
Abstract: A non-crosslinked, decellularized and purified mammalian tissue (e.g., bovine pericardium) having particular use as an implantable resorbable material. The material is treated by alkylating its primary amine groups in a manner sufficient to reduce the antigenicity of the tissue, permitting the treated tissue to be used in vivo and without crosslinking, and in turn, permitting it to be resorbable. The material can be used in surgical repair of soft tissue deficiencies for a certain period of time while the implant itself is gradually remodeled or absorbed by the host. Also provided are a method of preparing such a material, as well as a method of using such a material for surgical repair.
Patent AT-E418613-T1 (AT)
Inventor: BURNIE JAMES
IPC: G01N33/53
Filed: 2000-10-09
Granted: 2009-01-15
Abstract: The present invention concerns antimicrobial compositions in particular compositions which affect Burkholderia cepacia, together with diagnostic test for same and uses of same.
Patent AT-E259360-T1 (AT)
Inventor: BUSSE JULIETTE KHARSA
IPC: C07D217/26
Filed: 2000-10-19
Granted: 2004-02-15
Abstract: Methods for the preparation of chemical intermediates in the synthesis of HIV-protease inhibitors related to and including nelfinavir mesylate are disclosed. The method of this invention comprises converting tetrohydran derivatives into oxazolines to provide key reaction intermediates for the preparation of nelfinavir. Also disclosed is a method for the preparation of a chiral amino alcohol from an epoxy-tetrahydrofuran.
Patent AT-E326900-T1 (AT)
Inventor: MARRO DOMINIC P
IPC: A61B5/00
Filed: 2000-10-27
Granted: 2006-06-15
Abstract: A patient module comprising an 8 channel EEG pre-amplifier whose signal acquisition and processing characteristics are optimized for use in the operating room and intensive care unit. This patient module comprises at least an optimized multistage input filter, an optimized input stage circuit topography, ultra-isolation, oversampling, a multiplexer inter-sample charge dump, and high performance low-frequency-enhanced shielding.
Patent AT-E318511-T1 (AT)
Inventor: ERNEUX CHRISTOPHE
IPC: A01K67/027
Filed: 2000-10-31
Granted: 2006-03-15
Abstract: The present invention is related to an inhibitor of the inositol polyphosphate 5-phosphatase SHIP2 protein or its encoding sequence identified by SEQ ID NO. 1. The present invention is also related to a pharmaceutical composition comprising said inhibitor and an adequate pharmaceutically acceptable carrier or diluent and to a non-human knock-out mammal comprising homozygously or heterozygously a partial or total deletion in its genome of the inositol polyphoshate 5-phosphatase SHIP2 nucleotide sequence.
Patent AT-E341342-T1 (AT)
Inventor: PRESSLER MILLTON LETHAN
IPC: A61K31/403
Filed: 2000-11-30
Granted: 2006-10-15
Abstract: Combinations of ACE inhibitors and vasopressin antagonists are useful to slow and reverse the process of ventricular dilation, and CHF in mammals.