baber/WOPTO huggingface dataset:
Patent JP-5324093-B2 (JP)
IPC: A61K47/48
Filed: 2005-07-25
Granted: 2013-10-23
Abstract: The present invention relates to novel materials based on biodegradable polyamino acids that are useful especially for the vectorization of active principle(s) (AP). The invention further relates to novel pharmaceutical, cosmetic, dietetic or phytosanitary compositions based on these polyamino acids. The object of the invention is to provide a novel polymer starting material that is capable of being used for the vectorization of AP and makes it possible on the one hand to achieve high polymer/AP ratios, and on the other hand optimally to satisfy all the specifications required in the case in point: biocompatibility, biodegradability, ability to associate easily with numerous active principles or to solubilize them, and ability to release these active principles in vivo. This object is achieved by the present invention, which relates first and foremost to linear polyamino acids comprising aspartic units or glutamic units and having hydrophobic grafts comprising hydrophobic groups containing from 8 to 30 carbon atoms, at least one of these hydrophobic grafts having at least one anionic charge and/or one or more mutually identical or different ionizable groups each capable of giving rise to at least one anionic charge. These polymers are amphiphilic and anionic and are capable of being converted easily and economically to particles for the vectorization of active principles, these particles themselves being capable of forming stable aqueous colloidal suspensions.
Patent JP-4884387-B2 (JP)
IPC: A61P25/00
Filed: 2005-08-08
Granted: 2012-02-29
Abstract: The present invention is directed to novel 2-amino-3,4-dihydro-quinazoline derivatives, pharmaceutical compositions containing them and their use in the treatment of Alzheimer's disease (AD) and related disorders. The compounds of the invention are inhibitors of beta-secretase, also known as beta-site cleaving enzyme and BACE.
Patent JP-4974890-B2 (JP)
IPC: A61P35/00
Filed: 2005-05-24
Granted: 2012-07-11
Abstract: A therapeutic oligomer-peptide conjugate, and methods of using the conjugate are disclosed. The conjugate includes (a) a substantially uncharged oligonucleotide analog compound having a base sequence that includes a string of bases that are complementary to four or more contiguous cytosine bases in a target nucleic acid region to which the compound is intended to bind, and (b) conjugated to the compound, an arginine-rich peptide effective to enhance the uptake of the compound into target cells. The string of bases in the compound includes at least one inosine base positioned in the string so as to limit the number of contiguous guanine bases in said string to three or fewer. The conjugate has greater cellular uptake than the compound alone, by virtue of the arginine-rich peptide, and substantially greater antisense activity greater activity than the conjugate in the absence of inosine-for guanine substitutions.
Patent JP-5324096-B2 (JP)
IPC: D01F6/04
Filed: 2005-09-01
Granted: 2013-10-23
Abstract: A polyethylene multi-filament yarn is provided, which comprises a polyethylene having an intrinsic viscosity in decalin at 135°C of from 5 dl/g to 35 dl/g, fewer than two methyl groups per thousand carbon atoms, and less than 2 wt. % of other constituents. The yarn has a tenacity of at least 17 g/d as measured by ASTM D2256-02. The filaments of the yarn have a peak value of the ordered-sequence length distribution function, F(L), as determined at 23°C from the low frequency Raman band associated with the longitudinal acoustic mode (LAM-1), at a straight chain segment length L of at least 40 nanometers.
Patent JP-5032327-B2 (JP)
IPC: H04B10/00
Filed: 2005-10-11
Granted: 2012-09-26
Abstract: A device that detects an effect which distorts a communication signal in a serial communication channel comprises an input, a detector connected to the input, a demultiplexer having a data input connected to the output of the detector, and an evaluator at each output of the demultiplexer. The input receives the distorted communication signal from the communication channel. The detector detects a feature in a symbol of the distorted communication signal and outputs the detected feature. The demultiplexer outputs the detected feature and has a plurality of control inputs. A differently delayed symbol (i−1, 1, i+1) of the communication signal is applied to each input to switch the detected feature present at the input of the demultiplexer to an output of the demultiplexer specified by the symbols present at the control inputs.
Patent JP-4988606-B2 (JP)
IPC: C12N15/09
Filed: 2006-02-28
Granted: 2012-08-01
Abstract: Disclosed herein are methods and compositions for treatment of conditions requiring inhibition of angiogenesis, said methods and compositions involving the use of zinc finger proteins that bind to particular target sites of the pigment epithelium-derived protein (PEDF) gene and regulate its expression. Such conditions include those characterized by neovascularization, such as retinopathies, macular degeneration and various malignancies.
Patent JP-5343359-B2 (JP)
IPC: H01L23/12
Filed: 2008-01-09
Granted: 2013-11-13
Abstract: <P>PROBLEM TO BE SOLVED: To reduce formation cost compared to conventional methods by obtaining conduction between an upper and lower layers.  <P>SOLUTION: The conduction between the upper and the lower layers can be obtained by a semiconductor device 10 including: a semiconductor chip 11 on the surface of which a circuit layer 12 is formed; a re wiring layer 15 formed on the circuit layer 12; a conductive post part 16 as a protruded electrode formed on the rewiring layer 15; a wire 17 having a first end and a second end, and the first end of which is connected to the rewiring layer 15; and a sealing resin 18 for sealing the semiconductor chip 11, rewiring layer 15, conductive post part 16 and wire 17, in which the upper part of the conductive post 16 and the second end are exposed outside.  <P>COPYRIGHT: (C)2009,JPO&INPIT
Patent JP-5276856-B2 (JP)
IPC: A63F5/04
Filed: 2008-02-20
Granted: 2013-08-28
Abstract: <P>PROBLEM TO BE SOLVED: To prevent an unexpected privilege from being imparted to a player, in a slot machine which determines whether or not to impart a privilege (control to a specified state) to the player after the end of a special game state in the special game state.  <P>SOLUTION: In a game while control is executed to a big bonus based on the winning of the independently won big bonuses (A)-(C), RT navigation drawing for determining whether or not to execute RT navigation (winning reporting of a role for controlling a game state to advantageous RT) after the end of the big bonus is performed corresponding to the kind of a character selected by the player at the start. While the big bonus is ended when the putout total number of medals from the start exceeds 465, even when the putout total number of medals does not exceed 465 and the big bonus continues, the RT navigation drawing is not executed when the putout assumed number of medals in the case of assuming that all internally won small roles are won exceeds 466.  <P>COPYRIGHT: (C)2009,JPO&INPIT
Patent JP-5311861-B2 (JP)
IPC: H01M10/0587
Filed: 2008-03-31
Granted: 2013-10-09
Abstract: <P>PROBLEM TO BE SOLVED: To provide a lithium secondary battery having high energy density, high discharge-rate characteristics, and excellent charge discharge cycle characteristics.  <P>SOLUTION: In the lithium secondary battery having an electrode body 5 formed by spirally winding a laminated body including a negative electrode in which a negative active material layer containing an element having a coefficient of cubic expansion by charge of 1.9 times or more is formed on a negative current collector, a positive electrode in which a positive active material layer containing a lithium transition metal oxide is formed on a positive current collector, and a separator, and housing the electrode body 5 in a cylindrical battery container with a nonaqueous electrolyte impregnated, two positive current collector tabs 7, 7 are arranged at intervals of at least 1/4 or more of the total length of the positive electrode in a position from an inner peripheral side end part in the winding direction of the positive electrode to 2/3 of the total length of the positive electrode, and one negative current collector tab 8 is arranged in an outer peripheral side end part in the winding direction of the negative electrode.  <P>COPYRIGHT: (C)2010,JPO&INPIT
Patent JP-5095473-B2 (JP)
IPC: H04W64/00
Filed: 2008-04-08
Granted: 2012-12-12
Abstract: Provided is a radio communication device including a reception unit that receives a radio signal, a measurement unit that measures a field intensity of the radio signal received by the reception unit, a determination unit that determines whether the radio signal received by the reception unit satisfies a predetermined condition for a noise component, and an estimation unit that estimates a distance from a transmission source device of the radio signal based on the field intensity of the radio signal determined by the determination unit to satisfy the predetermined condition.
Patent JP-4621268-B2 (JP)
IPC: C07K14/47
Filed: 2008-05-07
Granted: 2011-01-26
Abstract: The present invention relates to a method for diagnosing cancers by measuring proteins associated with tumorigenesis and metastasis, and more particularly provides a method for diagnosing cancers by measuring the changes of glycosylation of tissue inhibitor of matrix metalloproteinase-1 (TIMP-1), and a kit for diagnosis of cancers using the said method. The method and kit of the present invention can effectively be used for the sensitive diagnosis of cancers comprising colon cancer, stomach cancer, lung cancer and liver cancer.
Patent JP-5298636-B2 (JP)
IPC: H01L29/786
Filed: 2008-05-21
Granted: 2013-09-25
Abstract: <P>PROBLEM TO BE SOLVED: To provide a heterocyclic oligomer compound having a pentafluorosulfanyl group which has high electron stability and electron mobility and is stable in the atmosphere, and to provide a method for producing the same.  <P>SOLUTION: Provided are the heterocyclic oligomer compound having a pentafluorosulfanyl group and the pentafluorosulfanyl group-having heterocyclic oligomer compound which is a pentafluorosulfanyl group-having thiophene oligomer compound represented by general formula (1) [wherein, R is a 1-6C alkyl group or pentafluorosulfanylphenyl group; (n) is an integer of 2 to 4].  <P>COPYRIGHT: (C)2010,JPO&INPIT
Patent JP-5187005-B2 (JP)
IPC: B60L50/16
Filed: 2008-06-04
Granted: 2013-04-24
Abstract: <P>PROBLEM TO BE SOLVED: To more properly maintain a state of a battery when selection of an EV mode is cancelled in a plug-in type hybrid car.  <P>SOLUTION: In the hybrid vehicle 20, residual capacity "SOC" (residual capacity at the cancel) of a battery 50 at a selection cancel of an EV mode is set as a control center "Scc" when selection of the EV mode is cancelled, and charge and discharge request power "Pb*" which is target charge and discharge power of the battery 50 is basically set so as to be maintained within a target range (control center "Scc"±α) which makes the control center "Scc" to be a center (step S1120, S1140, S1155 to S1175). Moreover, the engine 22 is started if the residual capacity "SOC" of the battery 50 becomes to be not larger than a lower limit value ("Scc"-α) of the target range which makes the residual capacity at the cancel to be the center when the selection of the EV mode is cancelled and an operation of the engine 22 is stopped.  <P>COPYRIGHT: (C)2010,JPO&INPIT
Patent JP-5345344-B2 (JP)
IPC: B01D61/12
Filed: 2008-06-20
Granted: 2013-11-20
Abstract: <P>PROBLEM TO BE SOLVED: To provide a supply control method for a scale inhibitor, which can reduce the amount of a scale inhibitor supplied to water to be treated in a water treatment system such as a recovery system of industrial wastewater.  <P>SOLUTION: In the supply control method for a scale inhibitor, which controls the supply of a scale inhibitor to water to be treated in a water treatment system, the water to be treated contains at least one of calcium, magnesium and silica, and an electrolyte other than these; the electric conductivity of the water to be treated is measured; and the amount of the scale inhibitor supplied to the water to be treated is adjusted in response to the electric conductivity measured.  <P>COPYRIGHT: (C)2010,JPO&INPIT
Patent JP-5359054-B2 (JP)
IPC: A63F13/52
Filed: 2008-06-24
Granted: 2013-12-04
Abstract: <P>PROBLEM TO BE SOLVED: To easily make an optional color correction in response to the moving position of a movable body.  <P>SOLUTION: The CPU 101 of a control apparatus 20 reads each control program which is stored in a storage apparatus 104, and acquires a color correction label which is set in the index of the applicable point when the movable body 50 passes a correction value switching point of a path 60 which is formed along a course 40. Then, the CPU 101 performs a color data correction process for correcting the luminosity by composing the correction value of color correction data corresponding to a color correction level to the correction value of the applicable color data. In the storage apparatus 104, various control programs as a color correction data setting means 120, a correction value switching point setting means 130, a correction value switching determining means 140, a color correction data acquiring means 150, and a color data correcting means 160 are stored. In addition, in the storage apparatus 104, an image database 170, a color correction index database 180, and a color correction value database 190 are stored.  <P>COPYRIGHT: (C)2010,JPO&INPIT
Patent JP-5270232-B2 (JP)
IPC: G01C9/06
Filed: 2008-06-25
Granted: 2013-08-21
Abstract: <P>PROBLEM TO BE SOLVED: To provide a measuring system and a clinometer capable of improving specific accuracy of a dangerous spot, while suppressing power consumption maximumly.  <P>SOLUTION: A signal processing part 11 has a mode switching means 14 for switching a normal mode for measuring a tilt angle at the first sampling period to/from an alert mode for measuring the tilt angle at the second sampling period which is shorter than the first sampling period. The mode switching means 14 switches an operation mode to the alert mode when the tilt angle is changed over the first threshold during operation in the normal mode, and switches the operation mode to the normal mode when a tilt angle change over the second threshold is not generated as long as an alert time during operation in the alert mode. When being switched from the normal mode to the alert mode, a synchronizing means 15 transmits an alert signal from a communication circuit 7 to another clinometer A in a measuring area, to thereby switch the operation mode to the alert mode also relative to another clinometer A.  <P>COPYRIGHT: (C)2010,JPO&INPIT
Patent JP-5374965-B2 (JP)
IPC: G06F11/22
Filed: 2008-08-25
Granted: 2013-12-25
Abstract: <P>PROBLEM TO BE SOLVED: To reduce a load of a designer and to shorten the design work.  <P>SOLUTION: A control serialization processing part 601 creates a management thread (main thread) 700 when branch_call command is called. A management mechanism 710 is placed in the management thread 700. The management mechanism 710 starts a first sub-thread 701 and a second sub-thread 702, and gives an execution instruction to a control program 602. In response to a restoration instruction from the control program 602, restoration is performed. The management mechanism 710 has a restoration time table which shows the time when control should be returned to a first script 201 and a second script 202.  <P>COPYRIGHT: (C)2010,JPO&INPIT
Patent JP-5359130-B2 (JP)
IPC: H04B1/3822
Filed: 2008-09-03
Granted: 2013-12-04
Abstract: <P>PROBLEM TO BE SOLVED: To solve the following problem: when another system is additionally employed in the conventional radio base station system where a certain system is already employed, etc., a radio controller and a radio device for each system are required in the conventional system.  <P>SOLUTION: A radio base station device has a rate conversion part which samples a base band signal of a first communication system at a clock rate of common multiples of a clock rate of the first communication system and a clock rate of a second communication system different from the clock rate of the first communication system. The another radio device has a frequency discrimination part which receives the base band signal of the first communication system sampled at the clock rate of the common multiples of the clock rate of the first communication system and the clock rate of the second communication system different from the clock rate of the first communication system and a base band signal of the second communication system, discriminates frequencies, and divides the received base band signals to the base band signal of the first communication system and the base band signal of the second communication system.  <P>COPYRIGHT: (C)2010,JPO&INPIT
Patent JP-5276397-B2 (JP)
IPC: B29C45/00
Filed: 2008-09-25
Granted: 2013-08-28
Abstract: <P>PROBLEM TO BE SOLVED: To provide a sandwich molded product which can be fastened by easily driving a screw without elaborately drilling a hole, and a method for manufacturing a sandwich molded product.  <P>SOLUTION: The sandwich molded product 3 is constituted of a core layer 1 composed of an expandable synthetic resin 1a and a skin layer 2 composed of a synthetic resin 2a covering the core layer 1. In addition, an exposed part 4 in the core layer where the synthetic resin 1a of the core layer 1 is located pushing the synthetic resin 2a in the skin layer 2 aside, and is exposed to the surface, is arranged in part of the surface and also, part of the surface, on the opposite side, of the skin layer 2, which is opposed to the above part of the surface of the skin layer 2, with the core layer 1 sandwiched in between.  <P>COPYRIGHT: (C)2010,JPO&INPIT
Patent JP-5329892-B2 (JP)
IPC: B61C17/12
Filed: 2008-09-29
Granted: 2013-10-30
Abstract: <P>PROBLEM TO BE SOLVED: To provide an underfloor device for a rolling stock and a method of manufacturing the same excellent in assembling workability with good manufacturing efficiency.  <P>SOLUTION: The underfloor device includes a bottom wall unit 30, a side wall unit 40, a ceiling wall unit 50 and a partition wall unit. Each side wall unit is joined with the bottom wall unit by fastening a side wall 41 to a bottom wall 31 with a fastening member, a wiring 44 of the side wall unit is connected to an electric component of the bottom wall unit, the partition wall unit is joined with the bottom wall unit by fastening a partition wall to the bottom wall with a fastening member, a first cutout of the partition wall is overlapped to a wiring 36 on the bottom wall, and a wiring of the partition wall unit is connected to the electric component of the bottom wall unit. The ceiling wall unit is joined with the side wall unit and the partition wall unit by fastening a ceiling wall 51 with the side wall and the partition wall with a fastening member, a second cutout of the partition wall is overlapped to wiring 53 of the ceiling wall, and the wiring of the ceiling unit is connected to the electric component of the bottom wall unit.  <P>COPYRIGHT: (C)2009,JPO&INPIT
Patent JP-4989625-B2 (JP)
IPC: A61F2/06
Filed: 2006-04-14
Granted: 2012-08-01
Abstract: A catheter system and method are described for stenting a vessel at a bifurcation or sidebranch of the vessel. The catheter system includes a first balloon catheter, a second balloon catheter and a releasable linking device for holding the first and second balloon catheters arranged in a side-by-side configuration and aligned with one another along a longitudinal axis. The linking device allows the catheter system to be advanced as a unit and helps prevent premature or inadvertent dislodgement of the stent from the catheters, yet is releasable so that one or both of the balloon catheters can be released from the linking device and maneuvered separately from the rest of the catheter system when desired. The method utilizes the described catheter system for stenting bifurcated vessels using a modified “kissing balloons” technique.
Patent JP-4700731-B2 (JP)
IPC: H05K3/46
Filed: 2006-06-27
Granted: 2011-06-15
Abstract: According to embodiments of the present invention, an XFP optical transponder module includes a dual board flexible circuit. In embodiments, the dual board flexible circuit includes two printed circuit boards coupled together via a connector. In one embodiment, the connector is a flexible printed circuit. In an alternative embodiment, the connector is a plug-socket assembly.
Patent JP-5043020-B2 (JP)
IPC: B60R16/02
Filed: 2006-09-28
Granted: 2012-10-10
Abstract: The method for diagnosing possible faults in vehicle components, e.g. a fuel injector (2.1) or gearbox (2.2), comprises memorizing the distance traveled when a symptom linked to the possible failure occurs. A second distance is memorized, which is either a fixed distance, when the symptom is looked for again, or the distance after which it disappears. Independent claims are included for: (A) a computer (C) programmed to carry out the method; (B) an engine (1) fitted with the computer; and (C) a system comprising the engine and a separate diagnostic unit (4).
Patent JP-4996621-B2 (JP)
IPC: B65D25/42
Filed: 2006-12-27
Granted: 2012-08-08
Abstract: There is described a spout (4) for opening devices (3) of sealed packages (1) of pourable food products. The spout (4) has an annular flange (7) fixable to a respective package (1), and a tubular neck portion (8) projecting from the flange (7) and defining, with the flange, a through opening (6) through which to pour the food product; and the spout (4) also has, at least at a section crosswise to the axis (A) of the opening (6), a constriction (13) constricting flow of the pourable food product.
Patent JP-5270388-B2 (JP)
IPC: B22D17/26
Filed: 2009-01-27
Granted: 2013-08-21
Abstract: <P>PROBLEM TO BE SOLVED: To provide a device for rotating tie bar nut, where the attaching and removing of a tie bar nut are performed in a short period of time, and the drawing-out operation of the tie bar can be efficiently performed.  <P>SOLUTION: The device for rotating tie bar nut is composed of: a tie bar nut rotating means 4 constituted of a motor 8 mounted on a supporting base 7, a pinion gear 9 fixedly provided to the output shaft 8a of the motor 8 and a pinion shaft 10 pivotally supported by the supporting base 7 and engaged with a tie bar nut 3 and the pinion gear 9; a tie bar pressing means 5 consisting of a tie bar pressing body 12 inserted into the square hole 11a of the body 11, a screw shaft 14 in which the rear part 14b is screwed and inserted into the screw hole 12a of the tie bar pressing body 12, and the top 14a is connected to one end of a link 13, a hydraulic cylinder 16 pivotally supported by a bracket 15 erected at the upper face of the body 11 and a piston rod 17 held so as to be freely advanced/retreated by the hydraulic cylinder 16, and whose tip part is pivotally supported by the link 13 via a fixing tool 17a; and an extended tie bar 6.  <P>COPYRIGHT: (C)2010,JPO&INPIT