baber/WOPTO huggingface dataset:
Patent BR-PI1011031-B1 (BR)
Title: Composição líquida farmaceuticamente aceitável e Kit
Inventor: MARA NEMAS
IPC: A61K31/198
Filed: 2010-05-17
Abstract: COMPOSIÇÃO LÍQUIDA FARMACEUTICAMENTE ACEITÁVEL E KIT Divulgados neste documento estão sais de arginina de carbidopa e levodopa e composições que incluem, por exemplo, o sal de arginina de carbidopa adequado para administração contínua para o tratamento de doenças neurológicas ou motoras ou doenças como a síndrome das pernas inquietas, Doença de Parkinson, parkinsonismo secundário, doença de Huntington, síndrome semelhante à doença de Parkinson, PSP, MSA, ALS, síndrome Shy-Drager e condições resultantes de lesão cerebral, incluindo monóxido de carbono ou intoxicação por manganês, juntamente com a administração de levodopa.
Patent BR-PI1011511-B1 (BR)
Title: Unidade de ponta aplicadora para uso em um aparelho para aplicar formulações na pele em combinação com um motor
Inventor: KENNETH A PILCHER
IPC: A61M35/00
Filed: 2010-05-24
Abstract: "unidade de ponta aplicadora" a unidade de ponta inclui urna parte de base que é suficientemente rígida para ser convenientemente inserível em e removível de 5 uma extremidade de acionamento de um motor para o aplicador e uma parte de ponta que é fixada com segurança à parte de base por fundição ou moldagem e é suficientemente macia para prover contato confortável com a pele, a parte de ponta tendo uma superficie de frente côncava para receber formulações de pele que são aplicadas à pele, tal corno a pele facial, de um 10 usuário durante operação do aplicador.
Patent BR-PI1102825-B1 (BR)
Title: Dispositivo e método de processamento de informação, e, meio de armazenamento legível por computador
Inventor: TAKURO NODA
IPC: G06F3/0485
Filed: 2011-06-30
Abstract: dispositivo e método de processamento de informação, e, programa é fornecido um dispositivo de processamento de informação incluindo uma seção de formação de imagem para formar imagem de um objeto, uma seção de exibição configurada para exibir pelo menos um ícone para controlar a seção de formação de imagem, uma seção de operação configurada para adquirir uma primeira operação e uma segunda operação no ícone, e um controlador configurado para, quando a seção de operação tiver adquirido a primeira operação, configurar um temporizador de acordo com uma quantidade de operar da primeira operação e mudar uma exibição do ícone na seção de exibição de acordo com um progresso do temporizador, e para, quando a seção de operação tiver adquirido a segunda operação ou quando o temporizador tiver expirado, fazer com que a seção de formação de imagem forme imagem do objeto.
Patent BR-PI1104413-B1 (BR)
Title: sistema e método de detecção de vazamento de gás, método de determinação da magnitude e da localização de vazamento de gás por meio de redes neurais e o uso em tubulação rígida e/ou flexível
Inventor: ANA MARIA FRATTINI FILETI
IPC: G06N3/02
Filed: 2011-09-19
Abstract: SISTEMA E MÉTODO DE DETECÇÃO DE VAZAMENTO DE GÁS, MÉTODO DE DETERMINAÇÃO DA MAGNITUDE E DA LOCALIZAÇÃO DE VAZAMENTO DE GÁS POR MEIO DE REDES NEURAIS E O USO EM TUBULAÇÃO RÍGIDA E/OU FLEXÍVEL. A presente invenção trata-se de um sistema e um método de detecção de vazamento de gás, um método de determinação da magnitude e da localização de vazamento de gás por meio de redes neurais e o uso em tubulação rígida e/ou flexível, O método de determinação da magnitude e da localização de vazamento de gás envolve a utilização de redes neurais para análise dos dados, que apresenta como vantagem a possibilidade de manipulação eficiente de grandes quantidades de dados e grande capacidade de generalização. Além disso, através dos modelos neurais não é necessário o monitoramento do operador através de computador para análise de gráficos gerados pelos sinais acústicos, pois os modelos neurais geram um alarme informando a ocorrência, o tamanho e a localização do vazamento. A rápida detecção e localização de vazamento através de um sistema eficiente de monitoramento são essenciais para reduzir e evitar acidentes de grandes proporções
Patent EA-000731-B1 (EA)
Title: PREPARATION OF (11beta, 16 beta)-21-(3-CARBOXY-3-OXOPROPOXY)-11-HYDROXY-2'- METHYL-5'H-PREGNA-1,4-DIENO[17,16-D]OXAZOLE-3,20-DIONE
Inventor: FORTE LUIGI
IPC: C07J71/00
Filed: 1996-12-04
Abstract: 1. A process for preparing the compound (l1β,16 β)-21-(3-carboxy-3-oxopropoxy)-11-hydroxy-2'-methyl-5'H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione of formula I   which comprises a) reacting the compound (l1 β,16 β)-11,21-dihydroxy-2'-methyl-5'H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione of formula II   with succinic anhydride in a (C1-C4)alkyl ester of a (C1-C4) carboxylic acid as the solvent, in the presence of a basic catalyst. b) washing the obtained reaction mixture with an aqueous acid solution at a pH of about 2.0-3.5, c) separating the organic phase, filtering and concentrating it to small volume to precipitate the compound of formula I, and then recovering it therefrom. 2. Process according to claim 1 wherein the solvent is ethyl acetate. 3. Process according to claim 1 or 2 wherein the basic catalyst is selected from trimethylamine, triethylamine, N-methyl-pyrrolidine, pyridine, 4-(N,N-dimethylamino)-pyridine, 4-(N,N-diethylamino)pyridine, collidine, picoline. 4. Process according to claim 1 or 2 wherein the basic catalyst is triethylamine. 5. Process according to claim 1 wherein the reaction temperature is from 0 and 60 degree C. 6. Process according to claim 1 wherein the reaction temperature is from 15 and 35 degree C. 7. Process according to claim 1 wherein the molar ratio between the compound of formula II and succinic anhydride is from 1-2 to 1-5. 8. Process according to claim 1 wherein the molar ratio between the compound of formula II and succinic anhydride is about 1-2.5. 9. Process according to claim 1 wherein the amount of basic catalyst is from 0.1 to 3 times the molar amount of the compound of formula II. 10. Process according to claim 1 wherein the amount of basic catalyst is from equimolar to 2 times the molar amount of the compound of formula II. 11. Process according to claim 1 wherein the aqueous acid solution is a solution of a diluted mineral acid.
Patent EA-001493-B1 (EA)
Title: Alcoholic treatment and homeopathic pharmaceutical product
IPC: A61K31/485
Filed: 1998-01-28
Abstract: A homeopathic drug for treating alcoholism, characterized in that it comprises exponented ethanol in centesimal dilution, preferably C 100/C10000 prepared predominantly based on distilled water.
Patent EA-005918-B1 (EA)
Title: Derivatives of tryptamine and analogous compounds, and pharmaceutical formulations containing them
Inventor: ZISAPEL NAVA
IPC: A61P5/06
Filed: 2001-09-25
Abstract: This invention relates to novel substituted tryptamines and related derivatives, as well as pharmaceutical compositions formulated therefrom. These compounds, compositions and their salts can be used in the manufacture of medicaments for interacting with the melatoninergic system. These compounds and conditions can be used for treating several types of medical conditions, such as central nervous system and psychiatric disorders (sleep disorders, epilepsy and other convulsive disorders, anxiety, neurodegenerative diseases), chronobiological-based disorders (jet lag, delayed sleep syndrome, shift-work, seasonal affective disorder), neoplastic conditions, and conditions associated with physiological senescence.
Patent EA-010523-B1 (EA)
Title: Methods, optical recording apparatus using such methods and optical recording medium for use by the methods and the apparatus
Inventor: STEK AALBERT
IPC: G11B7/125
Filed: 2001-11-12
Abstract: Methods and an optical recording apparatus using these methods are described in which an optimum write power of a radiation beam in the apparatus is set by writing a series of test patterns on the optical recording medium, forming a read signal from the patterns and processing the read signal. Such processing involves fitting a function, preferably a straight line, to parameters obtained from the read signal without having to perform a differentiation step. An optical recording medium for use by the methods and the apparatus is also described.
Patent EA-005697-B1 (EA)
Title: A method for preparing a collagen sponge
Inventor: SCHAUFLER ALFRED
IPC: A61L31/04
Filed: 2002-01-25
Abstract: A method of preparing a collagen sponge comprises mixing air into a collagen gel, so as to obtain a collagen foam which is dried. From the dried product thereby obtained, collagen sponge is obtained by isolating parts of sponge with a chamber diameter of more than 0.75 mm and less than 4 mm, or parts with an average chamber diagonal dimension of 3 mm. The collagen sponge may be used as a material for sealing wounds, possibly with a coating comprising a fibrin glue, such as a combination of fibrinogen, thrombin and aprotinin.
Patent EA-010016-B1 (EA)
Title: Novel polyethyleneglycol modified compounds and uses thereof
Inventor: YIN QUN
IPC: C07K14/52
Filed: 2004-05-12
Abstract: The present invention relates to a peptide-based compound comprising a peptide moiety and a poly(ethylene glycol) moiety wherein the poly(ethylene glycol) moiety (preferably linear) has a molecular weight of more than 20 Kdaltons (preferably from 20 to 60 KDaltons). The peptide moiety may be monomeric, dimeric or oligomeric. Such peptide-based compounds may optional include a linker moiety and/or a spacer moiety.
Patent EA-011102-B1 (EA)
Title: Equipment component monitoring and replacement management system
Inventor: LONG WAYNE R
IPC: G01M13/00
Filed: 2004-10-14
Abstract: A system for managing replacement components for equipment (300, 400) having a plurality of components each with a limited useful life has a computer (40) with a processor (100). The system includes a computer program module for defining a duty profile (220) comprising a plurality of usage cases for the equipment (300, 400), each usage case involving two or more of the plurality of components and specified operating conditions assumed to be experienced by the involved components during the execution of each of the usage cases. There are also a computer program module for determining a theoretical useful life for each component involved in a duty profile (220), the theoretical useful life being based on component useful life data under the specified operating conditions; and sensors (302, 402) for determining and monitoring the occurrence of equipment operation corresponding to a usage case.
Patent EA-011625-B1 (EA)
Title: Aluminum conductor composite core reinforced cable and method of manufacture
Inventor: HIEL CLEMENT
IPC: B05D3/02
Filed: 2004-10-22
Abstract: This invention relates to an aluminum conductor composite core reinforced cable (ACCC). A composite core for an electrical cable comprising: a plurality of fibers from at least one fiber type in one or more matrix materials, the resin surrounds and substantially wrapping each of the plurality reinforced fibers oriented substantially parallel to the core longitudinal axis and wt% of fibers in the composite is less 50%. The core comprises resin having extension properties exceeding extension properties of glass fiber. Said ratio fiber/resin is changeable to manufacture the core with changing set of physical properties.
Patent EA-011961-B1 (EA)
Title: Method of sealing an annular space in a wellbore
Inventor: BOSMA MARTIN GERARD RENE
IPC: E21B33/14
Filed: 2005-11-18
Abstract: A method of sealing a space in a wellbore formed in an earth formation, the method comprising the steps of inserting a plurality of swelleable particles into said space, the particles being susceptible to swelling upon contact with a selected fluid, and inducing said selected fluid to contact the swelleable particles whereby the swelleable particles swell so as to form a body of swollen particles in said space, which are susceptible to swelling upon contact with water from the earth formation and which include a matrix material provided with a compound soluble in said formation water, wherein the matrix material substantially prevents or restricts migration of the compound out of the swelleable particle and allows migration of said formation water into the swelleable particle by osmosis so as to induce swelling of the swelleable particle.
Patent EA-013384-B1 (EA)
Title: Method for coherence-filtering of acoustic array signal
Inventor: TANG XIAOMING
IPC: G01V1/36
Filed: 2006-06-06
Abstract: A method waveform processing technique utilizing signal coherence of the array data for processing signals having poor signal-to-noise ratio. Raw waveform data is first transformed into f-k (frequency-wave number) domain. A coherence function is then calculated and convolved with the data in the f-k domain, which effectively suppresses non-coherent signals in the data. For the remaining coherent data, the unwanted part is muted and the wanted part is retained and inverse-transformed to yield the coherence-filtered array waveform data. After this processing, small signals that are hidden in the original data are extracted with much enhanced coherence. Subsequent processing of the data yields reliable information about formation acoustic property
Patent EA-013506-B1 (EA)
Title: Anti-il-23 antibodies
Inventor: BEIDLER CATHERINE BRAUTIGAM
IPC: A61K39/395
Filed: 2006-08-23
Abstract: The present invention encompasses isolated antibodies, or antigen-binding portions thereof, that specifically bind to the p19 subunit of IL-23. These antibodies, or antigen-binding portions thereof, are high affinity, neutralizing antibodies useful for the treatment of autoimmune disease.
Patent EA-014232-B1 (EA)
Title: Stable protein formulations
Inventor: DALI MANICHA M
IPC: A61K38/17
Filed: 2006-12-19
Abstract: The present invention relates generally to stable formulations comprising CTLA4Ig molecules, including lyophilized, and liquid formulations for administration via various routes including, for example, routes such as intravenous (IV) and subcutaneous(SC) for treating immune system diseases and tolerance induction.
Patent EA-017914-B1 (EA)
Title: 1,4-DISUBSTITUTED 3-CYANO-PYRIDONE DERIVATIVES AND THEIR USE AS POSITIVE MODULATORS OF mGluR2-RECEPTORS
Inventor: CID-NUNEZ JOSE MARIA
IPC: A61K31/4412
Filed: 2007-03-15
Abstract: The present invention relates to novel compounds, in particular novel pyridinone derivatives according to Formula (I)wherein all radicals are defined in the application and claims. The compounds according to the invention are positive allosteric modulators of metabotropic receptors - subtype 2 ("mGluR2") which are useful for the treatment or prevention of neurological and psychiatric disorders associated with glutamate dysfunction and diseases in which the mGluR2 subtype of metabotropic receptors is involved. In particular, such diseases are central nervous system disorders selected from the group of anxiety, schizophrenia, migraine, depression, and epilepsy. The invention is also related to pharmaceutical compositions and processes to prepare such compounds and compositions, as well as to the use of such compounds for the prevention and treatment of such diseases in which mGluR2 is involved.
Patent EA-014095-B1 (EA)
Title: Device for treating and purifying a liquid product
Inventor: KISTEREV VALERIY EVGENYEVICH
IPC: B01D35/02
Filed: 2008-03-06
Abstract: The invention substantially relates to the distillery industry. The inventive device comprises a cartridge (3) with a filter and a body, which are secured on a bottle neck, and a manual pump (10) for supplying air inside the bottle.
Patent EA-019101-B1 (EA)
Title: Chain comprising a plurality of interconnected links
Inventor: WIENKE DIETRICH
IPC: A61B17/06
Filed: 2007-10-30
Abstract: The invention relates to a chain suitable to moor or anchor boats, to lash cargo in road, rail, water and air transportation or for conveying, hoisting, suspending or lifting applications, said chain comprising a plurality of interconnected links. More in particular the invention relates to a chain suitable for the above stated uses comprising a plurality of interconnected links, at least part of the links comprising polyolefin fibers and in particular ultrahigh molecular weight polyethylene (UHMWPE) fibers. The invention also relates to a method for enhancing the strength of such a chain.
Patent EA-018664-B1 (EA)
Title: Sulphur-containing fertilizers and process for the preparation thereof
Inventor: ANTENS JANY BIRGITTA MARIA
IPC: C05G3/70
Filed: 2010-01-29
Abstract: Process for the manufacture of sulphur-containing fertilizer compositions, comprising the steps of: a) providing a slurry of at least one phosphate-based fertilizer material selected from the group consisting of ammonium phosphates, ammonium phosphate based nitrogen-phosphorus-potassium (NPK) compounds, super phosphates and partially acidulated phosphate rocks; b) bringing said slurry into contact with at least one anionic surfactant and elemental sulphur; c) introducing the mixture obtained in step b) into a granulator unit in order to obtain granules of the fertilizer composition, wherein the at least one phosphate-based fertilizer material is present in an amount in the range of at least 50 wt.%, the elemental sulphur is present in an amount in the range of from 1 to 25 wt.% and the anionic surfactant is present in an amount in the range of from 0.001 to 3 wt.% based on the overall weight of the fertilizer composition. The present invention also provides a fertilizer composition.
Patent EA-023148-B1 (EA)
Title: Compositions of pd-1 antagonists and use thereof
Inventor: LANGERMAN SOLOMON
IPC: C07K16/00
Filed: 2009-08-25
Abstract: Therapeutic compositions for increasing a T cell response, comprising a fusion protein and a potentiating agent, and the use of said compositions in the manufacture of a medicament for increasing a T cell response for treating a disease treatable with an increased T cell response, are described. A method of increasing a T cell response in a mammal, comprising administering to the mammal a fusion protein and a potentiating agent is also disclosed.
Patent EA-026128-B1 (EA)
Title: Thermally stable oil-in-water emulsion comprising an oil that comprises polyunsaturated fatty acids and process for preparing same
Inventor: MAI JIMBIN
IPC: A61K9/66
Filed: 2011-04-06
Abstract: The present invention relates to a thermally stable oil-in-water emulsion comprising an oil comprising a polyunsaturated fatty acid in a concentration of 10 to 30% by weight of the emulsion, water, an emulsifier, and a water-soluble stabilizer in a concentration of 20 to 50% by weight of the emulsion selected from a mixture of sodium chloride and a monosaccharide, a mixture of propylene glycol and a monosaccharide, and glycerol. The emulsion has a pH of 2 to 7. The thermally stable oil-in-water emulsions remain flowable at a temperature of -40°C, and are free from a variation in particle size after 9 months in storage at a temperature of -40 to -15°C. A process for preparing the thermally stable oil-in-water emulsion is also disclosed.
Patent EA-024101-B1 (EA)
Title: Analgesic compounds, formulations comprising the same and use thereof in therapy
Inventor: DEFAUW JEAN MARIE
IPC: C07C219/26
Filed: 2012-01-13
Abstract: Provided are analgesic compounds of formula I and pharmaceutically acceptable salts thereof:wherein A isand R, R, R, R, R, R, R, R, R, Rand Rare disclosed herein and wherein one of A), B), and C) is present: A) Rand Rcombine to form -CH- or -(CH)-; B) Rand Rcombine to form a cyclopropyl group with the carbon to which they are attached; or C) Rand Rcombine to form -CH- or -(CH). Additionally, analgesic pharmaceutical formulations and methods of use employing the above compounds are provided.
Patent EA-028199-B1 (EA)
Title: Microdispersions of hydroxamated polymers and methods of making and using them
Inventor: LEWELLYN MORRIS
IPC: C08F20/56
Filed: 2011-12-19
Abstract: Disclosed herein are a method of producing microdispersions containing hydroxamated polymers by reacting water-in-oil microdispersions having vinyl polymers containing one or more pendant functional groups that react with hydroxylamine, with a hydroxylamine-free base substantially free of inorganic salt and containing less than 500 ppm hydrazine, along with the microdispersions thereby obtained.
Patent EA-024106-B1 (EA)
Title: 2-(1,2,3-triazol-2-yl)benzamide and 3-(1,2,3-triazol-2-yl)picolinamide derivatives
Inventor: BOLLI MARTIN
IPC: C07D417/14
Filed: 2012-11-07
Abstract: The present invention relates to 2-(1,2,3-triazol-2-yl)benzamide and 3-(1,2,3-triazol-2-yl)picolinamide derivatives of formula (I)wherein Ar, Q, and Rto Rare as described in the description, to their preparation, to pharmaceutically acceptable salts thereof, and to their use as pharmaceuticals, to pharmaceutical compositions containing one or more compounds of formula (I), and especially to their use as orexin receptor antagonists.
Patent EA-026086-B1 (EA)
Title: Statistical reservoir model based on detected flow events
Inventor: SHIRZADI SHAWN
IPC: E21B43/20
Filed: 2011-11-18
Abstract: Computerized method and system for deriving a statistical reservoir model of associations between injecting wells and producing wells. Potential injector events at which injection flow rate changes are interactively identified from time series measurement data of flow rates at the wells in a production field, with confirmation that some response to those injector events appears at producing wells. Gradient analysis is applied to cumulative production time series of the producing wells, to identify points in time at which the gradient of cumulative production changes by more than a threshold value. The identified potential producer events are spread in time and again thresholded. An automated association program rank orders injector-producer associations according to strength of the association. A capacitance-resistivity reservoir model is evaluated, using the flow rate measurement data, for the highest-ranked injector-producer associations. Additional associations are added to subsequent iterations of the reservoir model, until improvement in the uncertainty in the evaluated model parameters is not statistically significant.
Patent EA-030929-B1 (EA)
Title: Compositions and methods of enhancing immune responses to eimeria or limiting eimeria infection
Inventor: BARTA JOHN R
IPC: A61K39/012
Filed: 2014-02-14
Abstract: Vaccine vectors and methods of using the vaccine vectors to enhance the immune response to an Apicomplexan parasite and reduce the morbidity or mortality associated with subsequent infection are provided herein. The vaccine vectors include a polynucleotide encoding a Rhomboid polypeptide and optionally include an immune-stimulatory polypeptide suitably expressed on the surface of the vaccine vector.
Patent EA-035257-B1 (EA)
Title: Equipment and method allowing the direct use of powdered polymer in hydraulic fracturing
Inventor: PICH EMMANUEL
IPC: B01F3/12
Filed: 2016-09-06
Abstract: An installation for the dosing and dissolution of a powder polymer having a particle size in the range from 100 to 500 m intended to feed a feed pump (13) in hydraulic fracturing operations, successively includes a powder polymer supply, from a pressurized tilting truck (1) or from bags emptied by pneumatic conveying, a mechanism for transporting the powder polymer fed by a compressor (3), and provided with a polymer transportation check valve (4), a hopper (5) for receiving the powder polymer having a high level (6) and a low level (6), the hopper being equipped with a pulse jet cleaning dust filter, as well as with a mechanism for controlling the check valve and the compressor according to the high and low levels, a screw feeder (7) for dosing the powder polymer, positioned at the lower end of the hopper (5), the screw being equipped with a variable-speed motor capable of being remotely controlled, a blender in which the polymer dissolves.