baber/WOPTO huggingface dataset:
Patent AU-1276900-A (AU)
Title: Mutation of the parkin gene, compositions, methods and uses
Inventor: BRICE ALEXIS
IPC: C12Q1/68
Filed: 1999-11-18
Abstract: New nucleic acid (I) encodes human parkin protein and includes at least one of the following genetic alterations: (a) deletion of one or more exons, optionally in combination; (b) multiplication of exons; (c) point mutations; or (d) deletion or insertion of one or more contiguous base pairs. Independent claims are also included for the following: (1) a polypeptide (II) encoded by (I); (2) an antibody (Ab) specific for (II); (3) a nucleic acid probe (Ia) that hybridizes specifically with (I); (4) primer pairs for amplifying all or part of (I); (5) a method for identifying genetic alterations in the parkin gene by amplifying at least part of the gene and detecting the specified alterations; (6) a method for diagnosing susceptibility to parkinsonism by detecting a specified alteration in the parkin gene; (7) a vector containing (I); (8) a cell containing the vector of (8); and (9) a non-human animal containing (I) in its cells. ACTIVITY : None given. MECHANISM OF ACTION : None given. No biological data given.
Patent AU-1298799-A (AU)
Title: A process for making high purity fatty acid lower alkyl esters
Inventor: KENNEALLY COREY JAMES
IPC: C07H13/06
Filed: 1998-11-02
Abstract: Processes for the synthesis of high purity fatty acid lower alkyl esters comprise the steps of: (a) converting a fatty acid source to a product mixture comprising lower alkyl esters and by-products; (b) water-washing the product mixture at elevated temperature and elevated pressure to remove by-products; and (c) fractionally distilling the water-washed product mixture to obtain high purity fatty acid lower alkyl esters. At least a portion of the fatty acids have from about 20 to about 24 carbon atoms. The high purity lower alkyl esters have an acid value no greater than about 1.0.
Patent AU-1347397-A (AU)
Title: Use of injectable or implantable biomaterials for filling or blocking lumens and voids of the body
Inventor: RHEE WOONZA M
IPC: A61K38/00
Filed: 1996-12-18
Abstract: Methods for completely or partially blocking, augmenting, sealing, or filling various biological lumens and voids within the body of a patient are disclosed. Lumens include arteries, veins, intestines, Fallopian tubes, and trachea. Voids include various lesions, fissures, diverticulae, cysts, fistulae, aneurysms, or other undesirable voids that may exist within a patient's body. In the most general method of the invention, an effective amount of a biomaterial is administered (e.g., via injection, catheter, or surgical implantation) into the lumen or void. Preferred biomaterial compositions for use in the present invention are disclosed.
Patent AU-1444288-A (AU)
Title: Aromatic derivatives, their preparation and their use as antimicrobial agents
Inventor: MOSSE MADELEINE
IPC: A61K31/44
Filed: 1988-04-08
Abstract: Aromatic derivatives of formula 
<IMAGE>
 in which:
 - n denotes an integer between 2 and 10;
 - R1 and R2 are identical or different and denote a cycloalkyl group containing 3 to 6 carbon atoms, an alkyl containing from 1 to 6 carbon atoms, unsubstituted or substituted by a phenyl or benzyl group;
 or R1 and R2 form together with the nitrogen atom to which they are bonded a heterocyclic ring chosen from the 1-pyrrolidinyl, piperidino, 1-azepinyl, hexamethyleneimino, 4-methylpiperidino, 4-benzylpiperidino, 4-phenylpiperidino, 1,2,3,4-tetrahydro-2-isoquinolyl, morpholino and 1-imidazolyl groups;
 - R3 denotes a hydrogen, a halogen, a methyl or a phenyl;
 - R4 denotes a hydrogen, a halogen or a methyl;
 or R3 and R4, taken together with the benzene nucleus to which they are bonded, form a 1-naphthyl or 2-naphthyl group;
 - Y denotes a direct bond, a methyleneoxy group, a methylenethio group or a vinylene group;
 - R5 denotes an alkyl containing from 5 to 18 carbon atoms, a cycloalkyl containing from 3 to 8 carbon atoms, an adamantyl, 1-naphthyl, 2-naphthyl or phenyl group unsubstituted or substituted by one or 2 substituents chosen from halogen atoms, the trifluoromethyl group, the nitro group or the phenyl group;
 and their salts with inorganic or organic acids.
Patent AU-1565699-A (AU)
Title: Transmucosal formulations of levosimendan
Inventor: KURKELA KAUKO
IPC: A61F13/02
Filed: 1998-12-11
Abstract: A method of administering transmucosally, particularly to oral or nasal mucosa, levosimendan or a pharmaceutically acceptable salt thereof to a patient. The method comprises contacting an intact mucous membrane with a source of levosimendan, and maintaining said source with said mucous membrane for a sufficient time period to deliver levosimendan to the patient. Transmucosal preparations of levosimendan are also described. Levosimendan is useful in the treatment of heart failure.
Patent AU-1623488-A (AU)
Title: A parenteral device
Inventor: WHISSON MAXWELL EDMUND
IPC: A61M5/14
Filed: 1988-04-15
Abstract: A parenteral device (10) for the transfer of fluids to or from a living body. The device (10) comprises a body (11) having a chamber (18) and an opening (17) provided in the wall of the chamber (18). A hollow needle (19) is open at its outer end and is slidably mounted to the body (11) for axial movement therein. The needle (19) is movable between a first position in which it extends through said opening (17) such that its outer end extends beyond the body (11) and a second position in which the outer end of said needle is located innermost from said opening (17). A second aperture (21) in the wall of the needle (19) provides communication between the chamber (18) and the lumen of the needle (19) when in the first position.
Patent AU-1699783-A (AU)
Title: Maintaining ph in zn-bn cells
Inventor: GRIMES PATRICK GERARD
IPC: H01M10/52
Filed: 1983-07-19
Abstract: A method and apparatus for maintaining the pH level in a zinc-bromine battery 10 features reacting decomposition hydrogen formed during use of the battery with bromine in the presence of a catalyst 11, which is preferably ruthenium. The catalyst encourages the formation of hydrogen and bromine ions. The decomposition hydrogen is therefore consumed, whereby the pH of the system can remain substantially at a given value.
Patent AU-1763401-A (AU)
Title: Apparatus and method for assaying coagulation in fluid samples
IPC: G01N27/327
Filed: 2000-11-15
Abstract: This invention is a disposable cartridge (10) for use at the patient side to perform traditional coagulation assays on fresh whole blood or blood derivative samples. The cartridge (10), in use with an electronic analyzer allows a fluid sample to be metered and quantitatively mixed with reagents which activate the coagulation cascade. An artificial substrate for thrombin, the enzyme whose action results in clot formation is also provided. Clot formation is subsequently detected using a microfabricated sensor (29) also housed within the cartridge (10) which detects electrochemically the product of the thrombin reaction upon the synthetic substrate.
Patent AU-2017197-A (AU)
Title: A capsule for security closure of containers
Inventor: MORINI EMILIO
IPC: B65D41/34
Filed: 1996-12-23
Abstract: PCT No. PCT/IT96/00265 Sec. 371 Date Aug. 13, 1998 Sec. 102(e) Date Aug. 13, 1998 PCT Filed Dec. 23, 1996 PCT Pub. No. WO97/31839 PCT Pub. Date Sep. 4, 1997The invention relates to a closure (1) for the security closure of containers. It is usefully applied in the field of diagnosis and especially on containers full of a chemical reagent into which a sample of a substance to be analysed is injected. The closure (1) is provided with a cap (2) having at least one portion (3) made of a material which can be pierced by a syringe needle. The portion (3) is covered by a cover (4). The cap (2) is associated to a first security ring (5) such as to detach from the cap (2) in an axial direction to the container. A second security ring (6) is associated to the cover in such a way as to detach therefrom following a raising of the cover (4) so as to uncover the pierceable portion (3) and permit a needle to be introduced into the container.
Patent AU-2058001-A (AU)
Title: Dispenser apparatus and method
Inventor: TRAMONTINA PAUL F
IPC: B65H16/06
Filed: 2000-12-04
Abstract: A method and apparatus for more efficiently and easily dispensing paper products, such as toilet tissue, from commercial wall mounted dispensers. The dispenser may be reloaded, in most instances, in a single operation that requires only one hand. Further, the housing protects the paper from vandals and improper tampering, while still being configured for a simple reloading procedure without the necessity for using keys and the like to gain access to the housing. The apparatus may comprise spring loaded projections on the interior of the housing that are adapted to receive and suspend within the housing rolls of paper tissue. Doors within the housing are configured to allow insertion of a new roll of paper into the dispenser when located in the open position; further, such doors suspend the tail of the paper roll for easy access to the tissue user when the doors are in the closed position.
Patent AU-2188201-A (AU)
Title: A method of making a screen, a screen, and a system for making a screen
Inventor: SEYFFERT KENNETH WAYNE
IPC: B07B1/48
Filed: 2000-12-04
Abstract: A method for making a screen assembly for a vibratory separator, which, in certain aspects, includes placing a first layer of screening material below a glue application apparatus, and applying with the glue apparatus an amount of glue in a pattern to a portion of the first layer of screening material, unrolling part of a second layer from a second roll and positioning the part of the second layer adjacent part of the first layer to which glue has been applied, moving the part of the second layer and the part of the first layer between opposed rotatable spaced-apart rollers to press together the part of the second layer and the part of the first layer to form a pressed-together layer of first and second layers of screening material. In certain aspects hot glue is used and is cooled following application of the second layer on the first layer.
Patent AU-2307895-A (AU)
Title: Collagen preparation for the controlled release of active substances
Inventor: ROREGER MICHAEL
IPC: A61K47/42
Filed: 1995-04-15
Abstract: A collagen preparation for the controlled release of active substances is characterized in that it has mixtures of acid-insoluble collagens with different molecular weight distributions.
Patent AU-2413101-A (AU)
Title: Tongue stabilising device
Inventor: ROBERTSON CHRISTOPHER JOHN
IPC: A61F5/56
Filed: 2000-12-15
Abstract: A one piece tongue stabilizing device formed of a resiliently flexible material and comprises a body having a hollow interior within which the end of a user's tongue fits and is held by negative pressure. The body of the device comprises an entry portion having an opening to the hollow interior of the device and a bulb portion connected by a narrower diameter neck portion. Tabs extend from the bulb portion which in use engage the exterior of the user's face around the user's mouth or between the user's teeth and lips, to hold the tongue forward to assist in opening user's airway and reducing snoring. A major benefit of the device of the invention is that it does not require specialist fitting or the taking of upper and lower jaw impressions of the patient to produce a tailored device for the patient.
Patent AU-2440897-A (AU)
Title: Method of measuring bilirubin
Inventor: SCHULTZ CECILIA Z
IPC: C12Q1/54
Filed: 1997-04-04
Abstract: An assay for detecting in a test sample, an analyte that undergoes auto-oxidation is disclosed. The assay comprises the steps of forming a reaction mixture by combining in an aqueous medium (i) a sample containing the analyte and (ii) a stabilizer that reduces the rate of radical mediated auto-oxidation of the analyte. The reaction mixture is incubated for a period of time and the rate of auto-oxidation is detected. When the detected rate of auto-oxidation is substantially zero, a sufficient quantity of an enzyme is added, that catalyzes the oxidation of the analyte. In the presence of the stabilizer, the analyte can be oxidized to a product species. The product species, the analyte, or both can be detected.
Patent AU-2447400-A (AU)
Title: Improvements relating to electrically heated vessels
Inventor: O'NEILL ROBERT ANDREW
IPC: A47J27/21
Filed: 2000-02-08
Abstract: An electrically heated vessel 1 includes a planar heating element which is pulled down into engagement with abutment means 4 in the vessel by a structure 14 fixed to the bottom of the vessel. The structure fixed to the bottom of the vessel may be a thermally sensitive control device and/or a cordless component, such as a 360{ connector component accessible by a complementary connector component through an opening in the bottom of the vessel 5. The abutment means may be integral with the vessel, or may be non-integral and placed into the bottom of the vessel prior to introduction of the heating vessel (see fig 3). Sealing means 11 may be provided between the periphery of the heating element and the internal wall of the vessel, which may be in the form of a ring of elastomeric material extending around the periphery of the heating element, having one or more circumferential fins 13 engaging the internal wall of the vessel 2. The vessel may be dimensioned so as to permit the heating element to be assembled into the vessel through an opening in its top. Alternatively the vessel may comprise two parts, ie an open bottomed part with an opening through which the heating element is assembled, and a top part secured to the bottom part. Such electrically powered vessels may be used as kettles, hot water jugs, pots, pans, urns, and laboratory equipment.
Patent AU-2449495-A (AU)
Title: Air filtering apparatus with filtered air recirculation
Inventor: CATTIN GABRIEL
IPC: B01D46/46
Filed: 1995-04-27
Abstract: PCT No. PCT/FR95/00553 Sec. 371 Date Dec. 18, 1995 Sec. 102(e) Date Dec. 18, 1995 PCT Filed Apr. 27, 1995 PCT Pub. No. WO95/29748 PCT Pub. Date Nov. 9, 1995A filtration installation including a time delay device which, at the time of a filter sleeve cleaning operation, establishes a cycle to exhaust filtered air towards the outside atmosphere instead of recycling it. The installation also includes a device for bypassing the filtered air that includes two shutters. One of the shutters controls a recycling of the filtered air and the other shutter controls the exhaustion of the filtered air to the outside atmosphere. These shutters are actuated via a control device under the control of time delay device
Patent AU-2460584-A (AU)
Title: 2-oxo-1,2,3,5-tetrahydroimidazo-(2,1-b) quinazolinyl derivatives
Inventor: JONES GORDON H
IPC: C07D487/04
Filed: 1984-02-15
Abstract: Compounds according to the formulaand the pharmaceutically acceptable acid addition salts thereof wherein:n is an integer of 1 to 6;R, is hydrogen or alkyl of 1 to 4 carbon;R<sub>2</sub> is hydrogen or R, and R<sub>2</sub> are combined to form a carbonyl group;R<sub>3</sub> is hydrogen, alkyl of 1 to 6 carbons, phenyl, benzyl, hydroxy lower alkyl and its acylates, carbamoyl alkyl, carboxyalkyl, alkoxycarbonylalkyl or amino acid side chains;R<sub>4</sub> is hydrogen, alkyl of 1 to 6 carbons, benzyl, or hydroxy lower alkyl;Y is hydrogen, alkyl of 1 to 4 carbon atoms, halo or lower alkoxy;is an amide forming group wherein the nitrogen substituents are: hydrogen; alkyl of 1 to 6 carbon atoms; hydroxyalkyl of 1 to 6 carbon atoms and its aliphatic acylates of 1 to 6 carbon atoms or aryl acylates of 7 to 12 carbon atoms; cycloalkyl of 3 to 8 carbon atoms or cycloalkyl lower alkyl of 4 to 12 carbon atoms wherein the cycloalkyl ring is unsubstituted or substituted with a lower alkyl, lower alkoxy, -OH, -OCOR<sub>5</sub>, halo, -NH<sub>2</sub>, -N(R<sub>5</sub>)<sub>2</sub>, -NHCOR<sub>s</sub>, -COOH, or -COO(R<sub>5</sub>) group wherein R<sub>s</sub> is lower alkyl; phenyl or phenyl lower alkyl wherein phenyl is unsubstituted or substituted with 1 or more lower alkyl, halo or lower alkoxy groups or an -NH<sub>2</sub>, -N(R<sub>5</sub>)<sub>2</sub>, -NHCOR<sub>5</sub>, -COOH, or -COOR<sub>5</sub> group wherein R<sub>5</sub> is lower alkyl; morpholinyl; piperidinyl; perhexylenyl; N-loweralkylpiperazinyl; pyrrolidinyl; tetrahydroquinolinyl; tetrahydroisoquinolinyl; (±)-decahydroquinolinyl or indolinyl. These compounds are cyclic AMP phosphodiesterase inhibitors useful as antithrombotic agents and the like in mammals. The compounds also have inotropic and anti-metastatic activities.
Patent AU-2561395-A (AU)
Title: Process and device for determining element compositions and concentrations
Inventor: HNILICA KLAUS D
IPC: G01N21/71
Filed: 1995-04-28
Abstract: PCT No. PCT/EP95/01625 Sec. 371 Date Feb. 24, 1997 Sec. 102(e) Date Feb. 24, 1997 PCT Filed Apr. 28, 1995 PCT Pub. No. WO95/30140 PCT Pub. Date Nov. 9, 1995The invention pertains to a process and a device for determining the composition and concentration of elements in material samples using laser-based plasma emission spectroscopy. The process comprises the following steps: a) transformation of a portion of the material sample (20) to be analysed to a plasma-like state (46) by means of a pulsed high-power laser (12) focussed on the material sample (20); b) spectral analysis of the radiation emitted by the plasma (46) using a spectrometer (26); c) measurement of the total emission spectrum (44) of the plasma (46) changing per laser pulse in one or more spectral ranges typical of the element, using a detector (40); and d) calculation of the composition and concentration of the elements based on the entire spectrum (44) of measured emissions, i.e. the sum of a number of measured individual spectra (42). The claimed device (10) comprises a high-power laser (12), a spectrometer (26) and at least one measuring head (14) with integrated radiation optics (22). The high-power laser (12) and the spectrometer (26) are geometrically and stereoscopically decoupled from the measuring head and are connected to each other via at least one waveguide.
Patent AU-2726399-A (AU)
Title: Pharmaceutical compositions for ulcer
Inventor: SOLDATO PIERO DEL
IPC: A61K31/4184
Filed: 1999-02-25
Abstract: Pharmaceutical compositions for the therapy and the prevention of ulcer and dyspepsia relapses comprising as essential components the following components a) and b): component a): one or more components selected from the conventional anti-ulcer products; component b): organic compounds containing the -ONO2 function, or inorganic compounds containing the -NO group, characterized in that they are NO nitric oxide donors.
Patent AU-2756100-A (AU)
Title: Diagnostic and protective antigen gene sequences of ichthyophthirius
Inventor: CLARK THEODORE G
IPC: C07K14/44
Filed: 2000-02-04
Abstract: The ciliated protozoan Tetrahymena exemplifies a recombinant system for the expression of heterologous nucleic acids, preferably on the plasma membrane surface. Integration of a heterologous nucleic acid into the  beta -tubulin gene, BTU1, of a paclitaxel-sensitive T. thermophila mutant that possesses btul-1K350M  beta -tubulin allele allows screening for transformants using negative selection, as transformants have restored paclitaxel resistance. Transgenic ciliated protozoa of the invention can serve as live vaccines. For example, transgenic Tetrahymena expressingIchthyophthirius multifiliis i-antigen protein on their surface are effective vehicles for vaccination of freshwater fish against infection by I. multifiliis.
Patent AU-2798489-A (AU)
Title: Hydrophilic colored contact lenses
Inventor: NARDUCY KENNETH W
IPC: C08J7/043
Filed: 1988-11-21
Abstract: There is disclosed a method for making colored hydrophilic contact lenses. A contact lens constructed of hydrophilic polymer that is substantially devoid of the functional groups -COOH, -OH, -NH-R, wherein R is hydrogen or C1 to C8 alkyl, -NCO and epoxy is provided. At least a portion of the surface of the lens is coated with a color coat comprising at least one pigment, binding polymer having functional groups selected from at least one of -COOH, -OH, and -NH-R, wherein R is hydrogen or C1 to C8 alkyl, and an additional compound having at least two groups per molecule of -NCO. The coated lens is subjected to conditions which cause the color coat to adhere to the lens.
Patent AU-2995499-A (AU)
Title: Matrices formed of polymer and hydrophobic compounds for use in drug delivery
Inventor: BERNSTEIN HOWARD
IPC: A61K9/22
Filed: 1999-03-08
Abstract: A lipid or other hydrophobic or amphiphilic compound (collectively referred to herein as "hydrophobic compounds") is integrated into a polymeric matrix for drug delivery to alter drug release kinetics. In embodiments where the drug is water soluble, the drug is released over longer periods of time as compared to release from the polymeric matrix not incorporating the hydrophobic compound into the polymeric material. In contrast to methods in which a surfactant or lipid is added as an excipient, the hydrophobic compound is actually integrated into the polymeric matrix, thereby modifying the diffusion of water into the microparticle and diffusion of solubilized drug out of the matrix. The integrated hydrophobic compound also prolongs degradation of hydrolytically unstable polymers forming the matrix, further delaying release of encapsulated drug.
Patent AU-3030500-A (AU)
Title: Regulatory protein pke no.83 from human keratinocytes
Inventor: KRAMER MICHAEL D
IPC: C12N15/12
Filed: 1999-11-19
Abstract: The invention relates to an isolated polypeptide which is the same as or similar to (i.e., has the same function and effect as) a protein which occurs naturally in human keratinocytes and is more strongly expressed when the keratinocytes are in their activated state. The invention also relates to an isolated nucleic acid which codes a polypeptide or protein of this type that is typical for human keratinocytes and to the use of said polypeptide and said nucleic acid for detection, especially diagnostic purposes and/or for therapeutic purposes or the use of reagents, especially recombinant vector molecules and antibodies, against molecules of this type. The inventive protein has the amino acid sequence shown in sequence protocol SEQ ID NO:3 or an allele or derivative of this amino acid sequence produced therefrom by amino acid substitution, deletion, insertion, or inversion, and the inventive nucleic acid has either the amino acid sequence shown in sequence protocol SEQ ID NO:1 or a nucleotide sequence complementary thereto or a partial sequence of one of these two nucleotide sequences or a nucleotide sequence which is completely or partially hybridizable one of these two nucleotide sequences.
Patent AU-3091100-A (AU)
Title: Absorbent articles
Inventor: FORSGREN-BRUSK ULLA
IPC: A61F13/511
Filed: 1999-12-15
Abstract: The invention relates to an absorbent article that includes a synergistic combination of a) a pH-regulating substance in the form of a partially neutralized superabsorbent material, and b) lactic acid bacteria wherein after being wetted and worn close to the skin, the article has a pH value in the range of 3.5-5.5, preferably within the range of 3.5-4.9, and most preferably within the range of 4.1-4.7.