baber/WOPTO huggingface dataset:
Patent AU-725690-B2 (AU)
Title: Linker arm for solid support oligonucleotide synthesis and process for production thereof
Inventor: PON RICHARD T
IPC: G01N37/00
Filed: 1996-12-13
Granted: 2000-10-19
Abstract: PCT No. PCT/CA96/00837 Sec. 371 Date Jun. 19, 1998 Sec. 102(e) Date Jun. 19, 1998 PCT Filed Dec. 13, 1996 PCT Pub. No. WO97/23497 PCT Pub. Date Jul. 3, 1997A linker arm for solid support oligonucleotide synthesis, the linker arm comprising formula (1), wherein: X1 is selected from the group consisting of -O-, -S-, -S(O)2-, -C(O)- and -N(R12)-; R12 is selected from the group comprising hydrogen, a substituted or unsubstituted C1-C20 alkyl group, a substituted or unsubstituted C5-C30 aryl group and a substituted or unsubstituted C5-C40 alkaryl group, X3 is -O- or -N(H)-; R1, R2, R3, R4 and R5 are the same or different and are selected from the group consisting of hydrogen, halide, a substituted or unsubstituted C1-C20 alkyl group, a substituted or unsubstituted C5-C30 aryl group and a substituted or unsubstituted C5-C40 alkylaryl group; n is 0, 1 or 2; and one of A' and B' is selected from the group consisting of hydrogen, halide, a substituted or unsubstituted C1-C20 alkyl group, a substituted or unsubstituted C5-C30 aryl group and a substituted or unsubstituted C5-C40 alkylaryl group, and the other of A' and B' has formula (2), wherein X2 is selected from the group consisting of -O-, -S-, -S(O)2- and -N(R13)-; R13 is selected from the group comprising hydrogen, a substituted or unsubstituted C1-C20 alkyl group, a substituted or unsubstituted C5-C30 aryl group and a substituted or unsubstituted C5-C40 alkaryl group; R6 and R7 are the same or different and are selected from the group consisting of hydrogen, halide, a substituted or unsubstituted C1-C20 alkyl group, a substituted or unsubstituted C5-C30 aryl group and a substituted or unsubstituted C5-C40 alkylaryl group; p is 0 or 1; and m is 0, 1 or 2. A process for producing the linker arm is also disclosed. The linker arm is useful in solid support oligonucleotide synthesis and is characterized by a desirable combination of stability against spontaneous hydrolysis and ease of intentional cleavage of the synthesized oligonucleotide from the linker arm.
Patent AU-603412-B2 (AU)
Title: Method and apparatus for producing parts by selective sintering
Inventor: DECKARD CARL R
IPC: B23K26/08
Filed: 1987-10-14
Granted: 1990-11-15
Abstract: A method and apparatus (10) for selectively sintering a layer of powder to produce a part comprising a plurality of sintered layers. The apparatus includes a computer (40) controlling a laser (12) to direct the laser energy onto the powder to produce a sintered mass. The computer either determines or is programmed with the boundaries of the desired cross-sectional regions of the part. For each cross-section, the aim of the laser beam is scanned over a layer of powder and the beam is switched on to sinter only the powder within the boundaries of the cross-section. Powder is applied and successive layers sintered until a completed part is formed. The powder may consist of a plastic, metal, ceramic, or polymer substance. In the preferred embodiment, the aim of the laser is directed in a continuous raster scan and the laser turned on when the beam is aimed within the boundaries of the particular cross-section being formed. Preferably, the powder dispensing mechanism includes a drum which is moved horizontally across the target area and counter-rotated to smooth and distribute the powder in an even layer across the target area. A downdraft system provides controlled temperature air flow through the target area to moderate powder temperature during sintering. <IMAGE>
Patent AU-659429-B2 (AU)
Title: Strand displacement amplification
Inventor: WALKER GEORGE T
IPC: C12Q1/68
Filed: 1992-01-31
Granted: 1995-05-18
Abstract: This invention relates a nucleic acid target amplification and detection method which operates at a single temperature and makes use of a polymerase in conjunction with an endonuclease that will nick the polymerized strand such that the polymerase will displace the strand without digestion while generating a newly polymerized strand.
Patent AU-759723-B2 (AU)
Title: Novel process to prepare microencapsulated formulations
Inventor: WANG WENHUA W
IPC: B01J13/22
Filed: 1999-11-10
Granted: 2003-04-17
Abstract: Provided is a method of encapsulating a chemical agent comprising: (a) combining particles of a chemical agent and an encapsulation effective amount of a first encapsulating agent in an aqueous solvent and (b), converting the first encapsulating agent to a polymer to form encapsulated particles of the chemical agent.
Patent AU-660465-B2 (AU)
Title: Increasing blood-brain barrier permeability with permeabilizer peptides
Inventor: KOZARICH JOHN W
IPC: A61K47/42
Filed: 1992-04-23
Granted: 1995-06-29
Abstract: Peptides called receptor mediated permeabilizers (RMP) increase the permeability of the blood/brain barrier to molecules such as therapeutic agents or diagnostic agents. The permeabilizer A-7 or conformational analogues can be intravenously coadministered to a host together with molecules whose desired destination is the interstitial fluid compartment of the brain. Alternatively, the permeabilizer A-7 or conformational analogues can be administered sequentially with the molecule(s) of interest and these molecules can also be administered by routes other than intravascular. The permeabilizer A-7 or conformational analogues allow these molecules to penetrate the blood-brain barrier and arrive in the interstitial fluid.
Patent AU-542454-B2 (AU)
Title: 1, 4-dihyrdopyridine derivatives
Inventor: CAMPBELL SIMON FRASER
IPC: C07D295/14
Filed: 1983-09-02
Granted: 1985-02-21
Abstract: 1,4-Dihydropyridine derivatives of the formula:-and their pharmaceutically acceptable acid addition salts; whereR is aryl or heteroaryl;R<sup>1</sup> and R<sup>2</sup> are each independently C<sub>1</sub>-C<sub>4</sub> alkyl or 2-methoxyethyl;Y is -(CH<sub>2</sub>)<sub>2</sub>-, -(CH<sub>2</sub>)<sub>3</sub>-, -CH<sub>2</sub>CH(CH<sub>3</sub>)- or -CH<sub>2</sub>C(CH<sub>3</sub>)<sub>2</sub>-;R<sup>3</sup> is hydrogen or a group selected from:-where R<sup>4</sup> is H, C<sub>1</sub>-C<sub>4</sub> alkyl, C<sub>3</sub>-C<sub>6</sub> cycloalkyl, -COO(C<sub>1</sub>-C<sub>4</sub> alkyl), -CH<sub>2</sub>COO(C<sub>1</sub>-C<sub>4</sub> alkyl), aryl, -S0<sub>2</sub>.aryl, or heteroaryl, and X is 0 or S;where R<sup>5</sup> is 1-pyrrolidinyl, -NH<sub>2</sub>, -NH(C<sub>1</sub>-C<sub>4</sub> alkyl), -N/C<sub>1</sub>-C<sub>4</sub> alkyl)<sub>2</sub>, or -NH(CH<sub>2</sub>)<sub>2</sub>N(C<sub>1</sub>-C<sub>4</sub> alkyl)<sub>2</sub>;where R<sup>6</sup> is C<sub>1</sub>-C<sub>4</sub> alkyl or aryl;where R<sup>7</sup> is -CONH(C<sub>1</sub>-C<sub>4</sub> alkyl) or -COO(C<sub>1</sub>-C<sub>4</sub> alkyl);where R<sup>8</sup> is -CN, -SO<sub>2</sub>(C<sub>1</sub>-C<sub>4</sub> alkyl) or -SO<sub>2</sub> aryl;(h) -CH<sub>2</sub>CO.R<sup>9</sup> where R<sup>9</sup> is -NH<sub>2</sub>, -NH(C<sub>1</sub>-C<sub>4</sub> alkyl), -NH.aryl or C<sub>1</sub>-C<sub>4</sub> alkoxy;(i) -SO<sub>2</sub>.R<sup>10</sup> where R<sup>10</sup> is -NH<sub>2</sub>, -N(C<sub>1</sub>-C<sub>4</sub> alkyl)<sub>2</sub> or C<sub>1</sub>-C<sub>4</sub> alkyl; and(j) -CO.R" where R" is H, halomethyl, -COO(C<sub>1</sub>-C<sub>4</sub> alkyl), -CH<sub>2</sub>O(C<sub>1</sub>-C<sub>4</sub> alkyl), -CH<sub>2</sub>CO(C<sub>1</sub>-C<sub>4</sub> alkyl), C<sub>1</sub>-C<sub>4</sub> alkyl, C<sub>1</sub>-C<sub>4</sub> alkoxy, aryl, heteroaryl, morpholino or 5-oxo-pyrrolidin-2-yl.The compounds have utility as anti-ischaemic and antihypertensive agents.
Patent AU-643899-B2 (AU)
Title: Hydroxamic acid containing polymers used as corrosion inhibitors
Inventor: FONG DODD W
IPC: C23F11/14
Filed: 1992-06-30
Granted: 1993-11-25
Abstract: Hydroxamic acid containing low molecular weight polymers have been found to be excellent corrosion inhibitors for iron and steel alloys in contact with industrial waters. When the waters contain hardness ions, such as calcium, magnesium, and mixtures thereof, the waters are preferably treated with combinations of the hydroxamic acid containing polymers and scale inhibiting/dispersing polymers, which polymers do not contain hydroxamic acid functional groups. The hydroxamic acid containing polymers, as well as the combination of hydroxamic acid and scale inhibiting/dispersing polymers may also both be formulated with other corrosion inhibitors.
Patent AU-710590-B2 (AU)
Title: A process for protecting fat-based aqueous emulsion products against metal-catalyzed oxidation and a product thus protected
Inventor: ENGELL ASTRID MARGRETHE
IPC: C11B5/00
Filed: 1997-03-06
Granted: 1999-09-23
Abstract: Fat-based aqueous emulsion products having a fat content of 10-95 % by weight comprising oxidation-sensitive fats/-oils and conventional additions, including optionally conventional antioxidants and emulsifiers, are admixed with a combination of citrate and lecithin in amounts which protect the product effectively against metal-catalyzed oxidation. The products are normally to contain 0.01-1 % by weight of citrate calculated as citric acid and 0.01-1 % by weight of lecithin, and the agents are preferably added to the aqueous part prior to the emulsification. The combination of citrate and lecithin serves as an effective metal chelator and can particularly replace EDTA which has previously been used as a metal chelator in such emulsion products.
Patent AU-657991-B2 (AU)
Title: A process for the production of paper
Inventor: CARRE BRUNO
IPC: D21H17/63
Filed: 1992-06-12
Granted: 1995-03-30
Abstract: PCT No. PCT/SE92/00417 Sec. 371 Date Jan. 3, 1994 Sec. 102(e) Date Jan. 3, 1994 PCT Filed Jun. 12, 1992 PCT Pub. No. WO93/01353 PCT Pub. Date Jan. 21, 1993.The present invention relates to a process for improved dewatering and retention in the production of paper, where an anionic retention agent based on starches, cellulose derivatives or guar gums having no cationic groups and an acidic solution of an aluminum compound are added to the stock containing lignocellulose-containing fibres and optionally fillers. The pH of the stock prior to the addition of the aluminium compound should be at least about 6 to obtain the desired cationic aluminium hydroxide complexes in the stock. The present invention is cost effective and insensitive to the content of calcium in the white water.
Patent AU-607543-B2 (AU)
Title: Arrangement for occluding openings on hearing aids or ear fitting pieces for hearing aids
Inventor: HAERTL CHRISTOF
IPC: H04R25/02
Filed: 1988-10-04
Granted: 1991-03-07
Abstract: These openings are, in particular, openings for the entry of sound and/or exit of sound and/or ventilation. A microporous diaphragm (14) of anti-adhesive material can be inserted into the respective opening (2, 11). 
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Patent AU-616699-B2 (AU)
Title: Tissue fragmentation and/or hemostasis
Inventor: BROADWIN ALAN
IPC: A61B17/00
Filed: 1988-09-29
Granted: 1991-11-07
Abstract: An apparatus having a vibratable tip (22) for ultrasonically disintegrating tissue in a surgical procedure and for aspirating the disintegrated tissue and fluid away from the surgical site (12) through an opening (24) in the tip. A connection (42) to the electrosurgical unit provides for delivery of RF cutting current, RF coagulating current or a blend thereof to the tip so that electrosurgical procedures can be conducted separately or simultaneously with ultrasonic aspiration through the tip. It thus is now possible, for example, to electrocauterize simultaneously with ultrasonic fragmentation with a single handheld surgical device. The simultaneous delivery of ultrasonic vibrations and RF current to the tip also has been found to increase the tissue fragementation rate.
Patent AU-610296-B2 (AU)
Title: A process for the removal of hydrogen sulfide from gases
Inventor: WAL WILLEM J J VAN DER
IPC: B01D53/34
Filed: 1988-11-28
Granted: 1991-05-16
Abstract: The invention relates to a process for the removal of hydrogen sulfide from gases by passing the gases in the presence of oxygen and steam over a catalytic absorption mass which contains inert porous support materials as support and catalytically active metal sulfides and/or metal oxides for the selective oxidation of hydrogen sulfide to elemental sulfur, the sulfur formed being simultaneously deposited on the absorption mass, and regenerating the charged catalytic absorption mass.
Patent AU-611243-B2 (AU)
Title: Treatment of mastitis and applicator therefor
Inventor: CORBY MICHAEL PETER
IPC: A61K31/10
Filed: 1988-12-22
Granted: 1991-06-06
Abstract: A method for treating mastitis which comprises the use of an infusion of an effective amount of (mon)oxychlorosene or sodium oxychlorosene in an aqueous carrier is disclosed. A mastitis treatment infusion applicator which comprises a body portion (1) including a compartment (2) containing a first material which is an aqueous carrier, a cap portion (3) including a compartment (4) containing a second material which is (mon)oxychlorosene or sodium oxychlorosene, a seal (5) arranged on either the body or cap portion to separate the two compartments, and seal-breaking means (6) arranged on either the cap or body portion respectively, wherein the cap and body portion are movable relative to one another between a first position in which the seal is intact and a second position in which the seal is broken and in which the materials in the two compartments may come into contact, at least the surfaces contacting the second material being fluorinated is also disclosed.
Patent AU-690705-B2 (AU)
Title: Carpet cleaning and restoring composition
Inventor: BILLMAN FRED L
IPC: D06M13/165
Filed: 1995-06-13
Granted: 1998-04-30
Abstract: An aqueous carpet cleaning composition restores properties of manufacturer finishes to carpeting which is composed of from about 0.5% to about 6.0% by weight of ethylene glycol n-hexyl ether, from about 0.05% to about 2.0% by weight of a water-soluble or water miscible fluorinated hydrocarbon which forms a water and oil repellent surface upon drying; from about 0.25% to about 5.0% by weight of a surfactant selected from the group consisting of nonionic surfactants and mixtures thereof; and from about 0.5% to about 7.0% by weight of a olefinic/acrylic polymer having an acid number from about 10 to about 450. The composition forms a non-tacky, soil repellent residue upon drying and restores the water repellent finish of the carpet.
Patent AU-752278-B2 (AU)
Title: Method of producing thiobarbituric acid derivatives
Inventor: URWYLER BERNHARD
IPC: C07D239/60
Filed: 2000-02-03
Granted: 2002-09-12
Abstract: Method of producing thiobarbituric acid derivatives of formula IwhereinR1 is SH, S<->M<+ >or CH3S-, and M<+ >is an alkali metal ion, by hydrogenolysis of a compound of formula IIwherein R2 is chlorine or CH3O-, witha) a hydrogenolysis agent in the presence of an inert solvent and by a direct reaction of the hydrogenolysis product with an alkali metal methylate in methanol, orb) with a hydrogenolysis agent in the presence of an inert solvent and in the presence of a methylation reagent, and subsequently with an alkali metal methylate in methanol, as well as the use of these compound of formula I in the production of 7-[(4,6-dimethoxy-pyrimidin-2-yl)thio]-3-methylphthalide.
Patent AU-696655-B2 (AU)
Title: Butylene oxide-ethylene oxide block copolymer surfactants as stabilizer coatings for nanocrystal formulation
Inventor: WONG SUI MING
IPC: A61K9/14
Filed: 1995-06-09
Granted: 1998-09-17
Abstract: This invention provides a composition comprised of nanoparticles containing a therapeutic or diagnostic agent having a nonionic polymeric surfactant as a surface modifier adsorbed on the surface thereof, the surfactant being a block copolymer of ethylene oxide and butylene oxide and a method of making such nanoparticles. The compositions exhibit reduced macrophage uptake and improved toxicological profiles and facilitate particle size reduction such that milling time can be reduced and/or sterile filtration of the nanoparticles can be accomplished.
Patent AU-759258-B2 (AU)
Title: Method for switching off a power supply in a dangerous situation and a corresponding safeguarding arrangement
Inventor: KAARNAMO ANTTI
IPC: G08B17/10
Filed: 1999-04-06
Granted: 2003-04-10
Abstract: The invention relates to a method for interrupting delivery of current from mains in a risk situation and to the related safety arrangement. The method and the safety arrangement utilise at least one smoke detector, such as a fire alarm (1) or a similar environment detector to give a message, such as an impulse when the surrounding conditions change and exceed pre-set limits, and a relay unit (2) or a similar switch connected to this, which is brought into conductive state by a message from the smoke detector. In accordance with the invention, the relay unit (2) is used to electrically connect the grounding wire (PE) and the neutral wire (Nsr) of the mains, resulting in part of the return current being directed on the basis of the conductor resistors to the grounding wire (PE), and in a normal situation there will then be imbalance in the zero sum current of the phase wire (L1) and the neutral wire (Nsr), and when this sum current value different from zero exceeds the excitation current value of the fault current safety switch (7), the fault current safety switch (7) is actuated, interrupting the delivery of current.
Patent AU-624813-B2 (AU)
Title: Immunoassay for the detection of alpha-haloacetamides
Inventor: FENG PAUL
IPC: A61K39/385
Filed: 1989-04-21
Granted: 1992-06-25
Abstract: Antigens, antibodies, antisera and diagnostic assay kits used in an enzyme-linked immunosorbent assay (ELISA) for  alpha -haloacetamide herbicides.
Patent AU-747976-B2 (AU)
Title: Simplified sequential chemiluminescent detection
Inventor: AKHAVAN-TAFTI HASHEM
IPC: C12Q1/42
Filed: 1999-04-16
Granted: 2002-05-30
Abstract: A method for sequential chemiluminescent detection of two differently labeled analytes on a single blot is described. In the method, a uniquely labeled DNA is detected with a horseradish peroxidase (HRP) substrate followed by the detection of another uniquely labeled DNA with a second different enzyme substrate which also inhibits the chemiluminescence generated by HRP. The sequential detection method described herein eliminates the need to strip and reprobe Southern, Northern and Western blots. Potential applications of this method include forensic DNA fingerprinting where more than one probe is used for probing a Southern blot, multiplex DNA sequencing of more than one template, detection of gene rearrangements, mutations and gene linkage.
Patent AU-666709-B2 (AU)
Title: Pyrimidine derivatives and processes for the preparation thereof
Inventor: ZIMMERMANN JURG DR
IPC: A61K31/505
Filed: 1993-04-02
Granted: 1996-02-22
Abstract: There are described N-phenyl-2-pyrimidinamine derivatives of the formula I <IMAGE> in which R1 denotes 4-pyrazinyl, 1-methyl-1H-pyrrolyl, phenyl substituted by amino or amino-lower alkyl, in which the amino group is in each case free, alkylated or acylated, 1H-indolyl or 1H-imidazolyl bonded to a five-membered ring carbon atom, or pyridyl which is bonded to a ring carbon atom, unsubstituted or substituted by lower alkyl and unsubstituted or substituted by oxygen on the nitrogen, R2 and R3 independently of one another each denote hydrogen or lower alkyl, one or two of the radicals R4, R5, R6, R7 and R8 each denote nitro, fluorine-substituted lower alkoxy or a radical of the formula II -N(R9)-C(=X)-Y)n-R10     (II> in which R9 stands for hydrogen or lower alkyl, X stands for oxo, thio, imino, N-lower alkylimino, hydroximino or O-lower alkylhydroxyimino, Y stands for oxygen or the group NH, n stands for 0 or 1 and R10 stands for an aliphatic radical having at least 5 C atoms or for an aromatic, aromatic-aliphatic, cycloaliphatic, cycloaliphatic-aliphatic, heterocyclic or heterocyclic-aliphatic radical, and the remainder of the radicals R4, R5, R6, R7 and R8 independently of one another each denote hydrogen, lower alkyl which is unsubstituted or substituted by free or alkylated amino, piperazinyl, piperidinyl, pyrrolidinyl or morpholinyl, lower alkanoyl, trifluoromethyl, free, etherified or esterified hydroxyl, free, alkylated or acylated amino or free or esterified carboxyl. These compounds can be used e.g. for the therapy of cancers.
Patent AU-672393-B2 (AU)
Title: Liquid compositions containing blends of carboxylic esters
Inventor: DAVIS KIRK EMERSON
IPC: C10M171/00
Filed: 1993-04-26
Granted: 1996-10-03
Abstract: This invention relates to a liquid composition comprising (A) at least one fluorine-containing hydrocarbon containing one to three carbon atoms; and a lubricant comprising (B) a blend of (1) at least one carboxylic ester of (I) a neo hydroxy compound selected from the group consisting of (i) a neo hydroxy compound with one to four hydroxyl groups, and (ii) a mixture of neo hydroxy compounds having an average of less than 3.5 hydroxyl groups per hydroxy compound, and (II) a monocarboxylic acylating agent selected from the group consisting of (i) a monocarboxylic acylating agent having four or five carbon atoms, and (ii) a combination of a (a) an monocarboxylic acylating agent having four or five carbon atoms and (b) an monocarboxylic acylating agent having from about 7 to about 15 carbon atoms, provided that greater than 55 % of the ester groups of (1) are derived from monocarboxylic acylating agent having four or five carbon atoms, and (2) at least one carboxylic ester of (III) a neo hydroxy compound selected from the group consisting of (iii) a neo hydroxy compound having five or more four hydroxyl groups per hydroxy compound, and (iv) a mixture of neo hydroxy compounds having an average greater than 4.5 hydroxyl groups per hydroxy compound, and (IV) a combination of a (a) an monocarboxylic acylating agent having four or five carbon atoms and (b) an monocarboxylic acylating agent having from about 7 to about 15 carbon atoms, provided that greater than 55 % of the ester groups of (2) are derived from (IVb). The liquid compositions are useful particularly as refrigeration liquids in refrigerators and air-conditioners including automotive, home and industrial air-conditioners.
Patent AU-563721-B2 (AU)
Title: Protective circuit for portable electric appliances
Inventor: CROWLEY GEORGE C
IPC: H02H5/08
Filed: 1985-01-30
Granted: 1987-07-16
Abstract: A non-resettable water actuated circuit interrupting means for use with a portable electric appliance such as a hair dryer to provide protection for the user against injury in the event that the appliance is accidentally dropped in water or otherwise develops leakage current. Both sides (14b, 14c) of the line are fused (34, 40) and circuit means (14a) are provided which respond to leakage current in the appliance (18) to provide separate circuits to blow out each of the fuses. Respective breakdown devices, e.g. gas triodes (52, 54), are rendered conductive when leakage current is detected by sensing member (26). One (52) connects fuse (34) across the supply via resistor (68) and the other (54) connects fuse (40) across the supply via resistor (60).
Patent AU-557687-B2 (AU)
Title: System for controlling an electromagnetic clutch for an automotive engine
Inventor: MIYAWAKI MOTOHISA
IPC: F16H63/50
Filed: 1985-01-30
Granted: 1987-01-08
Abstract: @ A system for controlling an electromagnetic clutch has a computer 54 which produces a clutch-engaging and clutch-disengaging engine reference speed signals in accordance with vehicle speed in a low vehicle speed range. Engine speed from sensor 51 is compared with the engine speed reference signals by a comparator 55. The clutch is engaged at a higher engine speed than a clutch engaging speed and disengaged at a lower engine speed than a clutch disengaging speed in accordance with the result of the comparison.