baber/WOPTO huggingface dataset:
Patent CA-2680837-A1 (CA)
Title: Mek ligands and polynucleotides encoding mek ligands
Inventor: ATZEL AMY
IPC: C12N15/66
Filed: 2008-03-27
Abstract: The invention relates to kinase ligands and polyligands. In particular, the invention relates to ligands, homopolyligands, and heteropolyligands that modulate MEK activity. The ligands and polyligands are utilized as research tools or as therapeutics. The invention includes linkage of the ligands, homopolyligands, and heteropolyligands to a cellular localization signal, epitope tag and/or a reporter. The invention also includes polynucleotides encoding the ligands and polyligands.
Patent CA-2683249-A1 (CA)
Title: Apparatus and method for control of a thermostat
Inventor: ALHILO ESAN A
IPC: G05D23/19
Filed: 2009-10-20
Abstract: A thermostat is provided that includes a temperature sensor for sensing ambient temperature, and a switching device that is configured to apply electrical power to a heating element when the switching device is activated. The thermostat further includes a processor that is configured to periodically determine for a finite switching time period a temperature delta value indicative of the difference between the sensed temperature and a desired set point temperature. The processor is further configured to calculate a duty cycle ratio of the switch activation time relative to the total switching time period. The calculated duty cycle ratio for determining the switch activation time is determined as a function of the temperature delta value, a duty cycle offset and a heat dissipation offset. The duty cycle offset and the heat dissipation offset are based on an average of a predetermined number of prior duty cycle ratios.
Patent CA-2684680-A1 (CA)
Inventor: CHU DEZ
IPC: G01V1/00
Filed: 2008-03-24
Abstract: The invention is a method for inferring the saturation and pressure change of a reservoir by combining the information from 4D (time-lapse) seismic and time lag data volumes (7) derived from the 4D seismic, well logs (4), and reservoir simulation results (when simulator results are available) and featuring one or more 4D well ties (1) for a quantitative 4D interpretation. The inventive method uses model-based inversion incorporating rock physics (2) at well locations (5), and is statistical-based (6) away from wells. The method thus allows integration (8) of rock physics model and reservoir simulation and honors 4D seismic change.
Patent CA-2686366-A1 (CA)
Title: A method and system of controlling a hydroelectric plant
Inventor: NICOSON REGINALD L
IPC: F03B15/06
Filed: 2009-11-26
Abstract: An embodiment of the present invention may incorporate an adaptive model based control (MBC) for determining a physical parameter, such as, but not limiting of, generator output, head (135), generator speed, or the like. The adaptive MBC  may reduce the need for pre-defined control curves. The adaptive MBC may receive a plurality of data on the hydroelectric plant (215) and then build an operating model (220,225,235). This model may then be used to forecast and/or control an output variable, such as, but not limiting of, a generator output of the hydroelectric plant (100). The control system (155) of an embodiment of the present invention may be configured to automatically and/or continuously monitor the hydroelectric plant (100) to determine whether a physical parameter is within a desired range.  Alternatively, the control system (155) may be configured to require a user action to the initiate operation. An embodiment of the control system (155) of the present invention may function as a stand-alone system. Alternatively, the control system (155) may be integrated as a module, or the like, within a broader system, such as a turbine control or a plant control system.
Patent CA-2690031-A1 (CA)
Inventor: BURGESS RICHARD
IPC: F17C13/06
Filed: 2008-06-05
Abstract: A method and apparatus for providing a gas to or from a pressurized cylinder is described. The apparatus includes a gas delivery device housing that houses and protects a gas control device configured to deliver gas to a user or device, and may also be adapted to provide gas to the pressurized cylinder in a refilling process. The housing includes a surface free from unnecessary depressions and/or protrusions to facilitate cleanability and enhance safety during use. Adjustment indicators and status indication elements disposed in or on portions of the housing are configured to enhance readability and recognition, which facilitates safe and efficient operation of the device. Adjustable elements to control a flow metric from the gas control device are adapted to facilitate adjustment by a user with a large hand and/or a user suffering from some diminished physical capability.
Patent CA-2690611-A1 (CA)
Inventor: DEFREES SHAWN
IPC: C07H19/10
Filed: 2008-06-12
Abstract: The current invention provides methods (e.g., large-scale processes) for the production of nucleotide sugars, which are modified with a polymeric modifying group, such as poly(alkylene oxide) moieties (e.g., poly(ethylene glycol) or poly(propylene glycol)) moieties. A typical process of the invention includes anion exchange chromatography followed by an ultrafiltration procedure, such as tangential flow filtration. The process of the invention provides modified nucleotide sugars in unexpectedly high purity and high overall yields.
Patent CA-2690848-A1 (CA)
Inventor: AUBIN JANE E
IPC: A61P19/00
Filed: 2008-06-09
Abstract: ERR.gamma. is expressed in bone and cartilage in vivo and osteoblastic and chondrocytic cells in vitro. ERR.gamma.y is a transcriptional activator of an osteoblast-associated osteopontin (OPN) and chondrocyte-associated (Sox9) gene in osteoblasts and chondrocytes respectively. Knockdown of ERR.gamma. expression by antisense oligonucleotide strategies in osteoblastic cell cultures reduces alkaline phosphatase activity. Together these findings indicate that ERR.gamma. is expressed in and plays a functional role in bone and cartilage. The results also indicate that agonists and antagonists of ERR.gamma. may be useful as therapeutic agents in a wide variety of diseases affecting bones and joints.
Patent CA-2691854-A1 (CA)
Title: Putters with enhanced alignment visualization
Inventor: MILLER SEAN
IPC: A63B53/04
Filed: 2008-06-19
Abstract: Putters and putter heads better camouflage the main body of the head and/or highlight the alignment aid. The top surface of the head (when viewed from a ball address orientation) may be finished in a non-reflective, matte finish, optionally, in a dark color and/or in a color or colors selected so as to blend into or match the color of a golf green. At least some portion of the shaft member may be colored and finished in this same manner. These features help in visualization of the alignment aid (which also may be designed to help in alignment). If desired, the club head and/or shaft color and finish may be customized based on the greens at a specific golf course, greens in a specific geographical region, greens of a specific grass type, greens at a specific time of year or under specific conditions, etc.
Patent CA-2693110-A1 (CA)
Inventor: RUPNIAK NADIA M J
IPC: A61K31/55
Filed: 2008-07-18
Abstract: The present invention relates to methods of promoting wakefulness in an individual by administering a carbamoyl ester or a pharmaceutically acceptable salt thereof.
Patent CA-2694990-A1 (CA)
Inventor: GOETSCH LILIANE
IPC: G01N33/574
Filed: 2008-07-25
Abstract: The present invention relates to mammalian antibodies, designated 12B1 and antigen-binding portions thereof that specifically bind to insulin-like growth factor I receptor (IGF-IR), preferably human IGF-IR. Also included are chimeric, bispecific, derivatized, single chain antibodies derived from the antibodies disclosed herein. Nucleic acid molecules encoding the mammalian antibodies as well as methods of use thereof are also disclosed. Also included are pharmaceutical compositions comprising these antibodies and methods of using the antibodies and compositions thereof for treatment and diagnosis of pathological hyperprolifer-ative oncogenic disorders associated with expression of IGf-1R.
Patent CA-2698682-A1 (CA)
Title: Use of a peptide as a therapeutic agent
Inventor: BEVEC DORIAN
IPC: A61P35/00
Filed: 2008-09-09
Abstract: The present invention is directed to the use of the peptide compound His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-OH  as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectious diseases, lung diseases, heart and vascular diseases and metabolic diseases.  Moreover the present invention relates to pharmaceutical compositions preferably in form of a lyophilisate or liquide buffer solution or artificial mother milk formulation or mother milk substitute containing the peptide His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-OH optionally together with at least one pharmaceutically acceptable carrier, cryoprotectant, lyoprotec-tant, excipient and/or diluent.
Patent CA-2699104-A1 (CA)
Inventor: CAVALLI FABIO
IPC: A61K38/18
Filed: 2008-09-09
Abstract: The present invention is directed to the use of the peptide compound Tyr-Leu-Leu-Pro- Ala-Gln-Val-Asn-Ile--Asp-OH  as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectious diseases, lung diseases, heart and vascular diseases and metabolic diseases.  Moreover the present invention relates to pharmaceutical compositions preferably in form of a lyophilisate or liquide buffer solution or artificial mother milk formulation or mother milk substitute containing the peptide Tyr-Leu-Leu-Pro-Ala-Gln-Val-Asn-Ile-Asp--OH  optionally together with at least one pharmaceutically acceptable carrier, cryoprotectant, lyoprotectant, excipient and/or diluent.
Patent CA-2700101-A1 (CA)
Inventor: TARREGA LLORET MIGUEL ANGEL
IPC: E06B3/46
Filed: 2010-04-14
Abstract: Simultaneous displacement device for sliding doors, being a first sliding leaf (7) joined to a first cogged belt (9) established between a first set of cogged pulleys (11) and (12) which rotate freely on a first axis (13) and second axis (14) respectively, and a second sliding leaf (8) joined to a second cogged belt (10) established between a second set of cogged pulleys (15) and (16) which rotate freely on said first axis (13) and second axis (14) respectively, said device comprising clutching means (2) which enable to adopt a first position where the first cogged belt (9) and the second cogged belt (10) move independently, and a second position where the first cogged belt (9) and the second cogged belt (10) move integrally to enable the simultaneous displacement of the first sliding leaf (7) and of the second sliding leaf (8).
Patent CA-2700214-A1 (CA)
Inventor: HANCOCK CHRISTOPHER PAUL
IPC: A61F2/00
Filed: 2007-10-09
Abstract: A surgical antenna for radiating microwave energy (e.g. frequency 500 MHz to 60 GHz) from a e.g. ceramic insertion tip (60) into biological tissue is disclosed. The tip is provided at the end of an elongate body which delivers the microwave energy to the tip via an inner conductor (30), an outer conductor (20) surrounding the inner conductor and a dielectric material (50) therebetween. The impedance of the insertion tip (60) is selected to improve impedance matching with the complex conjugate of the complex impedance of the tissue at a treatment frequency. For example the insertion tip may act as or include at least one quarter wavelength impedance transformer. By closely matching the antenna's impedance to the tissue, dynamic tuning (if used) can be performed much more efficiently. Impedance matching at the tip can also focus the radiated energy distribution.
Patent CA-2704232-A1 (CA)
Inventor: AVIGAN DAVID
IPC: G01N33/00
Filed: 2008-11-07
Abstract: The invention is concerned with fusions of dendritic cells and with tumor or cancer cells. Also provided are methods of making and using these cell fusions, including methods of adoptive immunotherapy as well as methods of stimulating anti-tumor immunity using fused cells and anti-CD3/CD28 antibodies.
Patent CA-2705954-A1 (CA)
Inventor: DAWSON STEVEN CLARE
IPC: B60P1/16
Filed: 2010-06-04
Abstract: The present invention is a telescopic composite cylinder that functions as a hydraulic hoist incorporating multiple cylinders formed of composite materials. The walls of the multiple cylinders may be formed of pultruded composite material, or a combination of composite materials. The cylinders of the hydraulic hoist may incorporate a plurality of piston and sleeve assemblies that are mounted so as to invoke a telescopic relationship between the multiple cylinders. The materials that the cylinders are formed of may create walls having a smooth surface that can eliminate problems facing hoists formed of other materials, for example, such as a honing process, fluid leakage and seal wearing problems. The hoist may be run on diesel fuel drawn from the tank of a vehicle. Additionally, the present invention may be releseably attached to a surface by way of a saddle mounting system.
Patent CA-2706118-A1 (CA)
Inventor: HILPERT JEAN-JACQUES
IPC: A01K11/00
Filed: 2008-12-11
Abstract: The invention relates to a marking device for identifying and marking an animal that is connected by a non-reversible engagement: a male portion (20) including a rod extending from a holder (10); and a female portion (5) including a cavity for interaction with the rod. According to the invention, the rod is surrounded at least partially with a foam (21) impregnated with a specific substance so that the foam (21) is compressed upon the engagement of said male and female portions.
Patent CA-2706309-A1 (CA)
Title: Generating and updating true vertical depth indexed data and log in real time data acquisition
Inventor: YANG XUEJUN
IPC: G06F9/44
Filed: 2008-11-13
Abstract: An invention for dynamically determining a trajectory of a drilled wellbore is provided. A method may include: receiving a piece of information including data converted from a measured physical characteristic of at least one of the wellbore or drilling the wellbore, the piece of information being relevant to determining a trajectory of the wellbore; and updating only a portion of the determined trajectory, a calculation of the portion of the determined trajectory being affected by the received data.
Patent CA-2710120-A1 (CA)
Inventor: GOERGENS ULRICH
IPC: A01N37/22
Filed: 2008-12-09
Abstract: The invention relates to a composition comprising at least one aminobenzamide compound or a salt thereof for controlling animal parasites, veterinary pharmaceutical compositions comprising at least one aminobenzamide of formula (I) for preventing infection with diseases transmitted through parasites, its use for the preparation of a veterinary pharmaceutical for con-trolling animal parasites, and a method for preventing infection with diseases transmitted through parasites.
Patent CA-2710325-A1 (CA)
Title: System information modification notification and detection in wireless communications
Inventor: KITAZOE MASATO
IPC: H04W48/12
Filed: 2009-01-09
Abstract: Systems and methodologies are described that facilitate notifying and detecting system information block (SIB) modification in subsequent modification periods. Access points can advertise information in a current SIB indicating a subsequent modification period in which the SIB will be modified.  Devices can receive the SIB and process the information to determine whether the SIB will be modified and in which modification period. This mitigates undesirable affects of utilizing paging to indicate SIB modification since devices read the SIB upon entering a cell, switching from active to idle mode, etc.
Patent CA-2710862-A1 (CA)
Title: Pharmaceutical composition for treating diabetes and preparation method thereof
Inventor: PAN JIE
IPC: A61K35/63
Filed: 2008-11-14
Abstract: A pharmaceutical composition for treating diabetes and preparation methods, quality control methods and uses thereof, said pharmaceutical composition is prepared by using silkworm shit and licorice as raw materials, it not only can reduce blood sugar, but also can improve flatulence.
Patent CA-2710960-A1 (CA)
Inventor: NIEMAN TIM
IPC: A61F2/06
Filed: 2001-11-21
Abstract: A high density microwall ePTFE structure with increased radial strength and suture retention and a method for producing the same. The inventive material also achieves a sizeable reduction in the wall thickness and porosity. The method of manufacture involves the manipulation of a standard extruded ePTFE graft. The graft is placed within a restraining tube and is balloon dilated (20) to approximately four times its original diameter, after which it is placed onto a like-sized mandrel (30) that provides an interference fit. This loaded mandrel is placed into a calendering device (40) where the entire graft wall is moved between metal plates until sufficiently calendered.  The loaded mandrel is then placed into a heated furnace or oven (80) at a temperature above the crystalline melt point of PTFE to lock the changes into the microstructure.  The final product has the desired characteristics of reduced wall-thickness, high density, above-average radial strength and enhanced suture retention.
Patent CA-2711380-A1 (CA)
Inventor: STENSTROEM LENNART
IPC: H01C7/12
Filed: 2009-01-22
Abstract: An arrester includes at least one elongate outer first housing (11) made of an electrically insulating material, a pair of electrical terminals (12, 13) at oppo-site ends of the first housing, an array of electrical components (14) arranged in the first housing that form a series path between the terminals, and a voltage grading ar-rangement (15) for providing a substantially uniform voltage gradient along the ar-rester, wherein the voltage grading arrangement comprises (i) an elongated outer sec-ond housing (17), and (ii) capacitor circuitry (20) arranged in the outer second housing, and wherein the outer second housing is arranged external to the outer first housing.
Patent CA-2712137-A1 (CA)
Inventor: ARMSTRONG JEAN
IPC: H04B10/00
Filed: 2008-01-29
Abstract: Methods and apparatus (100) for composing, generating and transmitting information-bearing optical signals are provided. An information-bearing electrical signal is composed (108) having desirable spectral properties, preferably configured to ensure that undesired interference between electrical spectral components generated in a square-law direct detection process (120) at a corresponding optical receiver (104) is substantially avoided. Predistortion (110) is advantageously applied to transmitted signals, in order to account for a nonlinear relationship arising in a modulation process (114) between electrical signal amplitude and cor-responding optical field amplitude. Orthogonal frequency division multiplexing (OFDM) techniques may be applied to composed signals having the desired characteristics, and additionally may facilitate the application of frequency domain equalisation (128) in order to mitigate transmission impairments, including dispersion.  Improvements in received signal quality, and/or transmission distance, may thereby be achieved, along with simplification of receiver configuration and operation.
Patent CA-2713098-A1 (CA)
Inventor: SVENSSON KENTH I
IPC: F01N3/10
Filed: 2008-05-01
Abstract: An apparatus for treating engine exhaust gas includes comprising an exhaust conduit for leading exhaust gases from an engine to an outlet, a particulate filter connected in the exhaust conduit to receive exhaust gas, a heat source connected in the exhaust conduit upstream of the particulate filter, and, a heat exchanger connected to receive exhaust gas exiting the particulate filter and arranged to heat a portion of the exhaust conduit upstream of the heat source and particulate filter. Heating the exhaust gases prior to entry into the particulate filter helps ensure oxidation of the trapped particulate matter.
Patent CA-2713693-A1 (CA)
Inventor: NORMAN KEVIN
IPC: C10G1/04
Filed: 2010-08-20
Abstract: An apparatus for processing oil in an oil recovery vacuum tank is described. The apparatus has an air supply inlet and at least one air distribution pipe with a plurality of apertures for releasing air. Also described is an apparatus for recovering oil incorporating a vacuum tank and the apparatus for processing oil. Also described is a transport vehicle incorporating the apparatus for recovering oil. Also described is a nozzle for insertion into an aperture in an air distribution pipe.
Patent CA-2713947-A1 (CA)
Inventor: CHEN HAI
IPC: H01H71/08
Filed: 2009-02-04
Abstract: A line terminal for a circuit breaker includes a body forming two opposing legs and a third leg. The opposing legs are configured to form a passage for receiving a stab from a panel board. The two opposing legs are biased toward each other, and each of the opposing legs has a convex surface facing the passageway for engaging and maintaining alignment of the stab. A fixed contact is attached to the third leg. The fixed contact connects to a moveable contact of a circuit breaker. An arc runner is connected to the third leg and at least partially encloses a perimeter of the fixed contact.
Patent CA-2713997-A1 (CA)
Title: New 2,3,4,5-tetrahydro-1h-pyrido[4,3-b]indole compounds and methods of use thereof
Inventor: HUNG DAVID T
IPC: A61P25/00
Filed: 2009-01-26
Abstract: This disclosure relates to new tricyclic compounds that may be used to modulate a histamine receptor in an individual. Compounds are described, including new 2,3,4,5- tetrahydro-1H-pyrido[4,3-b]indole compounds. Pharmaceutical compositions comprising the compounds are also provided, as are methods of using the compounds in a variety of therapeutic applications, including the treatment of a cognitive disorder, psychotic disorder, neurotransmitter-mediated disorder and/or a neuronal disorder.
Patent CA-2714756-A1 (CA)
Inventor: WIESE MARK
IPC: A47C7/40
Filed: 2010-09-13
Abstract: The invention relates to an item of seating furniture with seat depth adjustment, in which the seat is mounted displaceably relative to a backrest frame.     According to the invention, it is proposed to mount a pivotable lower backrest frame (17) on the backrest frame (7), said lower backrest frame being connected to the rear part of the seat (1). The displaceable seat thereby remains connected to the backrest, and a horizontal gap does not arise between the backrest and seat, which horizontal gap could impair the seating comfort and interfere in the overall appearance of the item of seating furniture; the seat depth adjustment according to the invention is in particular also suitable for use with synchronous mechanisms.
Patent CA-2715305-A1 (CA)
Inventor: CHAN ANDREW
IPC: C07K16/28
Filed: 2008-08-29
Abstract: The invention provides methods and compositions useful for modulating T cells, and disorders associated with the dysregulation thereof.
Patent CA-2717620-A1 (CA)
Title: Method of increasing available output from a controlled-output vehicle engine to a power take off
Inventor: BRIAULT TREVOR
IPC: B60K17/28
Filed: 2010-10-14
Abstract: A method of increasing power available from the engine of a controlled-output vehicle to power take off and a high output power take off (HOPTO) vehicle produced by application of the method. The method includes providing a split shaft powered by the engine and engaged with both a drive shaft and a HOPTO. The split shaft may selectably power either the drive shaft or the HOPTO. The method further includes enabling the engine to provide sufficient output while stationary to power the HOPTO at a selected level. The engine may be enabled to provide such output in a number of ways, for example by relocating the vehicle speed sensor to generate a speed signal while the vehicle is stationary.