baber/WOPTO huggingface dataset:
Patent MA-43328-B2 (MA)
Title: Lymphocytes t transfectés et récepteurs de lymphocytes t destinés à être utilisés en immunothérapie contre des cancers
Inventor: MAURER DOMINIK
IPC: C07K14/74
Filed: 2017-03-16
Abstract: La présente invention concerne des récepteurs de lymphocytes t (tcr) se liant à des antigènes associés à une tumeur (taa) pour cibler des cellules cancéreuses, des lymphocytes t exprimant ceux-ci, des procédés pour les produire, et des procédés pour traiter des cancers à l'aide de ceux-ci. En particulier, la présente invention concerne des récepteurs de lymphocytes t et leurs variants qui se lient à des molécules hla de classe i ou ii avec un peptide, par exemple igf2bp3-001, présentant la séquence d'acides aminés de kiqeiltqv (seq id no : 1). La présente invention concerne par ailleurs des peptides, des protéines, des acides nucléiques et des cellules pour une utilisation dans des procédés immunothérapeutiques. En particulier, la présente invention concerne l’immunothérapie du cancer. La présente invention concerne, en outre, des épitopes peptidiques des lymphocytes t associés à une tumeur, seuls ou en combinaison avec d'autres peptides associés à une tumeur, qui peuvent, par exemple, servir de principes pharmaceutiques actifs pour des compositions vaccinales qui stimulent les réponses immunitaires antitumorales, ou pour stimuler des lymphocytes t ex vivo et les transférer aux patients. Des peptides liés aux molécules du complexe majeur d'histocompatibilité (cmh), ou des peptides en tant que tels, peuvent également être des cibles d'anticorps, des récepteurs des lymphocytes t solubles et d'autres molécules de liaison
Patent CS-199229-B2 (CS)
Title: Method of obtaining polymers
Inventor: CLEMENTI ANACLETO
IPC: C08C2/06
Filed: 1971-02-16
Abstract: 1284045 Recovering polymers from solution SNAM PROGETTI SpA 19 April 1971 [18 Feb 1970] 22078/71 Heading C3P Polymers are recovered from solution in organic solvents by: (i) feeding the polymeric solution to a first stripper to which is also fed water and steam; (ii) discharging from said first stripper an overhead comprising steam and solvent, and a bottoms comprising polymer crumbs, water and solvent; (iii) subjecting the bottoms to flashing; (iv) subjecting the flashed bottoms to further stripping in a second stripper to which live steam is fed, the pressure in the second stripper being lower than in the first; (v) discharging from the second stripper an overhead comprising steam and solvent, and a bottoms comprising polymer crumbs and water; and (vi) separating the polymer crumbs from the water, e.g. by filtration. The steam fed to step (i) may be the overhead from step (v) which has been re-compressed and optionally mixed with live steam. Step (iii) may be effected by an expansion valve at the inlet to the second stripper. Solvent may be recovered from the step (ii) overhead. Diene polymers and copolymers may be recovered from various hydrocarbon solvents.
Patent CS-216528-B2 (CS)
Inventor: MUNK EDMUND
IPC: B65D21/02
Filed: 1980-04-02
Abstract: Vynález spadá do oboru manipulace s materiálem
a vztahuje se zejména na paletizaci.
Vynález řeší problém vytvoření stohovatelné
palety se stohovacími rozpěrkami, zabraňujícími
zaklínění nosných patek při stohování
tak, aby stohovací rozpěrky byly pevné
a nepodléhaly snadno opotřebení a po­
škození při manipulaci.
Problém je řešen tím, že stohovací rozpěrky
jsou vytvořeny jako část žlábkovltých
výztužných spojovacích žeber, čímž jsou
zpevněny.
Vynález je vhodný pro výrobu stohovatelných
palet lisovaných z nevzlínavé směsi
lignitocelulózových vláken.
Patent CS-221259-B2 (CS)
Title: Planet gearing
Inventor: NILSSON SVEN W
IPC: F16H37/08
Filed: 1976-06-01
Abstract: 1530363 Toothed and friction gearing SKF NOVA AB 2 June 1976 [4 June 1975] 22757/76 Heading F2Q In planetary gearing, coaxial shafts 4, 11 are provided intermediate driving and driven shafts 1, 20, and shaft 11 carries a planet carrier 12 having shafts 15 on which are rotatably mounted planet gear wheels 16 and planet friction wheels 17. The planet gear wheels 16 mesh a sun gear wheel 7 on shaft 4 and a toothed annulus 19 whilst planet friction wheels 17 engage a sun friction wheel on shaft 4 and a friction annulus 18. Shaft 4 also carries a planet carrier 5 having shafts 81 on which are rotatably mounted planet friction wheels 8 which engage a sun friction wheel 2 on shaft 1 and a friction annulus 10. Shaft 20 carries a planet carrier 22 having shafts 23 on which are rotatably mounted planet gear wheels 25, meshing a sun gear wheel on shaft 11 and a toothed annulus 27, and planet friction wheels 24 engaging a sun friction wheel 13 on shaft 11  and a friction annulus 26. The planet friction wheels 8 and friction annulus 10 are made of elastic material and adjustable pre-stress may be effected by a screwed ring 29. Planet friction wheel 17 is pre-stressed by an elastic wire ring 28.
Patent CS-208114-B2 (CS)
Title: Method of making the new 4-substituted thiazol-2-exan acids
Inventor: HESS FRIEDRICH K
IPC: A61K31/425
Filed: 1979-06-26
Abstract: Compounds of the formula   <IMAGE>   wherein R1 is hydrogen or alkyl of 1 to 4 carbon atoms; R2 is hydrogen, methyl or carboxyl; and A is pyridyl, benzodioxanyl or   <IMAGE>  where R3, R4 and R5, which may be identical to or different from each other, are each hydrogen, hydroxyl, alkoxy, alkyl, halogen, carboxyalkyl or nitro, or one of R3, R4 or R5 is dialkylamino, carboxamido, morpholino, piperidino, hydroxy-piperidino, cyano or phenyl; non-toxic salts thereof formed with an inorganic base when R1 is hydrogen and/or R2 is carboxyl; and non-toxic addition salts thereof formed with an organic base when R1 is hydrogen. The compounds are useful as antiallergics.
Patent CS-216679-B2 (CS)
Title: Lifting and pulling device
Inventor: DESPLATS ANDRE
IPC: B66D1/74
Filed: 1979-08-10
Abstract: A cable traction apparatus comprises at least two pulleys disposed in a common plane. A first pulley (3) receiving the load has a semi-circular-sectioned groove while the other pulley (7) has a V-shaped groove section. A presser mechanism (9, 10, 13) is provided for tensioning the cable in proportion to the load and is associated with the pulley (7) having the V-shaped groove. <IMAGE>
Patent CS-205107-B2 (CS)
Title: Device for electrostatic coating the dyes part.the ones water diluted
Inventor: BENEDEK GYOERGY
IPC: B05B5/043
Filed: 1977-11-01
Abstract: An electrostatic sprayer for spraying water-based paints has two or more electrodes mounted on an insulating holder and disposed in the path of the spray between the object to be coated and the outlet of the sprayer. The electrodes are at varying distances from the sprayer outlet and are connected to different potentials.
Patent CS-270574-B2 (CS)
Title: Mixture for thermoplastic shoe bottom material production
Inventor: BINET MARIANN ING
IPC: C08L51/06
Filed: 1987-10-09
Abstract: Shoesole material having improved resistance to ageing, oil and chemicals is prepared by dynamic vulcanisation of a blend of styrene/butadiene or  alpha -methyl styrene butadiene rubber and an at least partially crystalline olefin polymer at a temperature above the softening point of the olefin polymer. The compositions may also comprise other diene rubbers and styrene polymers.
Patent CS-238384-B2 (CS)
Title: Return roration prevention mechanism
Inventor: VADASZ JOZSEF
IPC: A01K89/02
Filed: 1982-10-19
Abstract: Mechanism for preventing the rotary motion in dependence of the angular velocity and angular acceleration, respectively, with a complete grasp, e.g. for inhibiting the reverse motion of fishing reels. The mechanism can be switched over into a mode of operation, in which unidirectional grasp may be maintained even in case, if n = O. The solution according to the invention ensures absolute safety under any conditions. At an intensive cast the rotating part carrying the pull-up arm is rotating in a reverse direction, and reaches in a short time the critical values of angular velocity and angular acceleration resulting in the automatized activity; in such a manner i.e. by the instant braking it can be inhibited that due to accumulated kinetic energy the rotating part should further rotate resulting in an entangled line. The two-way selector arm enables the selection of an instant or automtic mode of operation. By using the invention, material losses due to the damaged damyl may be avoided, time-consuming re-assembly becomes superfluous. There are further advantages involved: the design is simple, operation is noiseless, in course of winding at the instant action braking moment does not arise, as it happens with the reels with the traditional ratching mechanism.
Patent AU-770613-B2 (AU)
Title: Method and system for installing and transporting an offshore wind power station at sea
Inventor: RINTA-JOUPPI YRJO
IPC: F03D11/04
Filed: 2000-11-01
Granted: 2004-02-26
Abstract: A method and a system for installing an offshore wind power station (1) at sea and/or transporting one from sea e.g. for maintenance, said wind power station comprising a base (2) to be set on the sea bottom, and a tower (3) attached to the base, which wind power station is transported to a place of installation at sea by means of a transport vessel (4) and lowered to the sea bottom and/or lifted off the sea bottom and transported to land/ashore by means of a transport vessel. The wind power station is lowered by adding ballast water into a ballast water tank (6, 7) provided in the wind power station, and raised by reducing the amount of ballast water in the ballast water tank. The wind power station comprises a ballast water tank (6, 7).
Patent AU-713407-B2 (AU)
Title: Apparatus for use in preventing decubitis ulcers and in relaxation therapy
Inventor: COSANI ADOLFO
IPC: A61G7/057
Filed: 1997-01-31
Granted: 1999-12-02
Abstract: An apparatus in the form of a bed or chair for providing relaxation therapy and prevention of decubitis sores is distinguished by the use of flexible beams (2) of the nature of leaf springs. Instead of being lifted up and down by rather complex apparatus only a single shaft (3) carrying cams (4) is provided which acts on the leaf spring-like beams to flex them upwardly and/downwardly to provide the required action. Preferred cams provide no lifting action but only intermitted depressing action of these beams which reduces vertigo and nausea effects and can be slid onto a cam shaft in any one of a multiple alternative angular positions. This enables selection of the travelling wave action for relaxation therapy and of the decubitis preventing action. <IMAGE>
Patent AU-773023-B2 (AU)
Title: Connecting apparatus
Inventor: BYFIELD MICHAEL PATRICK
IPC: F16B5/00
Filed: 2000-11-14
Granted: 2004-05-13
Abstract: A connector for providing a load supporting connection between a first "supporting" structural member and a second structural member supported thereby comprises a flange and an integral web formed with one or an array of two or more spaced slots. The flange may also be formed with an array of spaced slots. In a preferred embodiment, the slots of the flange have a lower portion dimensioned to receive a head of a stud which projects from a surface of the supporting member and a coextensive upper portion dimensioned to receive the shank of the stud. The slots of the web have an upper portion dimensioned to receive a head of a stud which projects from a surface of the supported member and a coextensive lower portion dimensioned to receive the shank of the stud. In a preferred embodiment, the width of each shank receiving slot portion is less than the width of the respective stud head.
Patent AU-696372-B2 (AU)
Title: Homologous recombination for universal donor cells and chimeric mammalian hosts
Inventor: KUCHERLAPATI RAJU
IPC: C07K14/74
Filed: 1994-12-28
Granted: 1998-09-10
Abstract: Homologous recombination is employed to inactivate genes, particularly genes associated with MHC antigens. Particularly, each of the  beta 2- microglobulin gene and the IFN- gamma R gene is inactivated for reducing or eliminating the expression of functional MHC antigens. The resulting cells may be used as universal donor cells. In addition, embryonic stem cells may be modified by homologous recombination for use in producing chimeric or transgenic mammalian hosts, which may be used as source of universal donor organs, or as models for drug and transplantation therapies. Methods for homologous recombination in non-transformed mammalian somatic cells are also described.
Patent AU-563454-B2 (AU)
Title: Polymerization process
Inventor: DAVIES STEPHEN PARRY
IPC: C08F2/16
Filed: 1983-05-12
Granted: 1987-07-09
Abstract: Sterically stabilised aqueous polymer dispersions free from charged species are made by emulsifying in water ethylenically unsaturated monomer(s), soluble in water to the extent of 0.8% - 8% by weight but giving rise to a polymer which is insoluble, and polymerising the monomer(s) in that state in the presence of (a) a non-ionisable azo initiator which is water-soluble and substantially monomer-insoluble and (b) a block or graft copolymer stabiliser of specified structure.
Patent AU-559973-B2 (AU)
Title: (3.2.0)bicycloheptanone oxime ethers
Inventor: LI TSUNG TEE
IPC: A61K31/557
Filed: 1983-07-13
Granted: 1987-03-26
Abstract: Compounds useful in treating cardiovascular disorders are the carboxylic acids depicted in formulas (1) and (2)as well as their pharmaceutically acceptable, non-toxic salts and esters, wherein:n is an integer from one to four;R<sub>1</sub> is hydroxy;R<sub>2</sub> is hydrogen; orR<sub>1</sub> and R<sub>z</sub> together are an oxo group;R<sub>3 </sub>iswhereinA is -CH<sub>2</sub>-CH<sub>2</sub>-; trans-CH=<sub>CH</sub>-; -C≡C-; andR<sub>4</sub> is linear or branched alkyl of one to twelve carbons, cycloalkyl of three to eight carbons; phenyl optionally substituted with one or two identical substituents selected from the group consisting of lower alkyl, lower alkoxy, hydroxy, trifluoromethyl, and halo; or optionally substituted phenylalkyl.
Patent AU-780803-B2 (AU)
Title: Tartar control denture adhesive compositions
Inventor: RAJAIAH JAYANTH N
IPC: A61K6/838
Filed: 2000-12-08
Granted: 2005-04-21
Abstract: The present invention relates to a non-aqueous denture adhesive composition comprising a safe and effective adhesive amount of a denture adhesive, a safe and effective amount of an anticalculus agent; and non-aqueous denture adhesive carrier; wherein the anticalculus agent is a material effective in reducing calcium phosphate mineral deposition related to calculus formation. The present invention further relates to a method of delivering an anticalculus agent to the oral cavity and teeth, by applying the above composition to dentures, directly to the oral cavity, or applying it to both, and thereafter securing the dentures to the oral cavity.
Patent AU-732136-B2 (AU)
Title: Sealable chamber extrusion apparatus and method with seal controls
Inventor: SADINSKI ROBERT L
IPC: B29C48/07
Filed: 1998-12-17
Granted: 2001-04-12
Abstract: An extrusion system utilizes single or tandem extruders and a mixer-cooler to extrude a foamable extrudate through a die in a sealable chamber. The foamable extrudate is shaped and calibrated within the chamber. The die is mounted on the end of a gel tube projecting through a gland seal in a fixed bulkhead forming the upstream end of the chamber. The gel tube and mixer-cooler are mounted on a movable carriage, movement of which may be used to adjust the die with respect to shaping and calibrating equipment inside the chamber. The mixer-cooler achieves a selected narrow range of uniform viscosity of the melt at the die depending on the size of the product and density. The chamber is preferably a vacuum chamber producing low density foams. The product exits the chamber to atmosphere on a continuous basis through a submerged orifice in a water baffle immersion seal. The mixer-cooler enables a large size low density product to be produced with uniform cellular structure without cell collapse or density gradients, as the product is subjected to the pressure and temperature transformations passing from the chamber to atmosphere through the water. The seal includes the submerged orifice with a free wheeling guiding system upstream of the orifice. Immediately ahead of the guiding system, the parameters of the foam extrudate are sensed to control the configuration of the orifice on a continuous basis. Before the extrudate passes into the water baffle seal it moves over a floating dancer roll, the position of which controls a haul-off such as a vacuum belt at the tail end of the system. This avoids pushing on the extrudate.
Patent AU-562489-B2 (AU)
Title: Lyophilized radiographic imaging kit
Inventor: GROGG TERRY WINTON
IPC: A61K51/12
Filed: 1983-12-07
Granted: 1987-06-11
Abstract: A process for making a lyophilized composition useful for skeletal imaging whereby an aqueous solution containing an ascorbate, gentisate, or reductate stabilizer is contacted with tin metal or an alloy containing tin and, thereafter, lyophilized.Preferably, such compositions also comprise a tissue-specific carrier and a stannous compound. It is particularly preferred to incorporate stannous oxide as a coating on the tin metal.
Patent AU-653250-B2 (AU)
Title: Antibiotics LL-E19020 epsilon and LL-E19020 epsilon1
Inventor: CARTER GUY THOMAS
IPC: C07H13/04
Filed: 1992-09-08
Granted: 1994-09-22
Abstract: The invention provides antibiotics designated LL-E19020 Epsilon and LL-E19020 Epsilon1 which are derived from the microorganism Streptomyces lydicus ssp. tanzanius NRRL 18036.
Patent AU-611718-B2 (AU)
Title: 5-oxo-imidazo-(1,5-a)-thieno (2,3-e) pyrimidine derivatives
Inventor: WATJEN FRANK
IPC: A61K31/505
Filed: 1988-10-03
Granted: 1991-06-20
Abstract: New heterocyclic compounds having the general formula <CHEM>  wherein R<3> is <CHEM> or CO2R min wherein R min  is C1-6-alkyl, C3-7-cycloalkyl or C1-6-alkoxymethyl; R<4> is C1-6-alkyl; -S- is <CHEM> and wherein R<5> and R<6> independently are hydrogen, C1-6-alkyl, or aryl. The compounds are useful in psychopharmaceutical preparations as anticonvulsants, anxiolytics, hypnotics, and in improving the cognitive function of the brain of mammals.
Patent AU-683384-B2 (AU)
Title: A method and a blank for the production of horseshoes
Inventor: BACKMAN CLEMENS
IPC: B21K15/02
Filed: 1995-04-28
Granted: 1997-11-06
Abstract: PCT No. PCT/SE95/00471 Sec. 371 Date Nov. 1, 1996 Sec. 102(e) Date Nov. 1, 1996 PCT Filed Apr. 28, 1995 PCT Pub. No. WO95/30329 PCT Pub. Date Nov. 16, 1995A method and a blank for the production of horseshoes. The blank being made from a plane of plate the length and width of which are many times larger than its thickness and which is composed of at least two part-plates of differently hard materials which are joined to each other by explosion welding, the harder material forming an external lamina and the softer material an internal lamina in the finished, substantially U-shaped shoe.
Patent AU-773111-B2 (AU)
Title: Use of amino-substituted hydroxybenzophenones as photostable UV filters in cosmetic and pharmaceutical preparations
Inventor: HABECK THORSTEN
IPC: C07C225/00
Filed: 2000-04-18
Granted: 2004-05-20
Abstract: Amino-substituted hydroxybenzophenones (I) are used as photostable UV filters in cosmetic and pharmaceutical compositions for protecting human skin or hair against solar radiation, optionally in combination with other UV absorbers. Amino-substituted hydroxybenzophenones of formula (I) are used as photostable UV filters in cosmetic and pharmaceutical compositions for protecting human skin or hair against solar radiation, optionally in combination with other UV absorbers. [Image] R1>, R2>H, 1-20C alkyl, 2-10C alkenyl, 3-10C cycloalkyl or 3-10C cycloalkenyl, or NR1>R2> is a 5- or 6-membered ring; R3>, R4>1-20C alkyl, 2-10C alkenyl, 3-10C cycloalkyl, 3-10C cycloalkenyl, 1-12C alkoxy, 1-20C alkoxycarbonyl, 1-12C alkylamino, 1-12C dialkylamino, aryl, heteroaryl, nitrile, carboxylate, sulfonate or ammonium; X : H, COOR5> or CONR6>R7>; R5>-R7>H, 1-20C alkyl, 2-10C alkenyl, 3-10C cycloalkyl, 3-10C cycloalkenyl, (YO)oZ or aryl; Y : (CH2)x or CH(Me)CH2; x : 2-4; Z : Et, n-Pr, n-Bu or i-Pr; m : 0-3; n : 0-4; o : 1-20. Independent claims are also included for: (1) use of (I) as UV stabilizers in cosmetic and pharmaceutical compositions; (2) cosmetic and pharmaceutical compositions for protecting human skin or hair against UV light of wavelength 280-400 nm, comprising compounds (I) in a carrier, optionally in combination with other UV absorbers.
Patent AU-779856-B2 (AU)
Title: Process for extracting polyphenolic antioxidants from purine-containing plants
Inventor: HOVING HENDRIK DERK
IPC: A23L33/105
Filed: 2000-02-02
Granted: 2005-02-17
Abstract: A process for isolating polyphenolic antioxidants from purine-containing plant material, comprising the steps of:   (a) extracting the plant material with an hydroxylic extracting liquid preferably at low temperature; (b) adsorbing the extract obtained in step (a), preferably at low temperature; (c) desorbing the adsorbed material with a hydroxylic desorbing liquid, preferably at relatively high temperature; and   (d) concentrating and optionally drying the desorbed material.   The process is especially suitable for producing cocoa antioxidants ofr use in pharmaceutical, cosmetic and nutritional compositions.
Patent AU-663141-B2 (AU)
Title: Novel cationic compounds useful as drainage aids and stabilizers for rosin-based sizing agents
Inventor: PUDNEY IAN A
IPC: D21H17/56
Filed: 1992-12-31
Granted: 1995-09-28
Abstract: This invention generally provides a class of novel cationic resin comprised of a cross-linked polyamine having pendant tertiary and/or quaternary amine groups linked to amine groups in said polyamine by a hydrocarbon chain including a hydroxyl group in the  beta -position with respect to the polyamine chain. In general, these resins can comprise the reaction product of a polyamine having secondary amine groups, a crosslinking agent, and a cationizing agent having an epoxide group and a tertiary or quaternary amine (quaternary ammonium) group. These cationic resins have been found to be useful for a variety of operations in the manufacture of paper and paperboard, especially as drainage aids and stabilizers for dispersed rosin sizing agents.
Patent AU-761002-B2 (AU)
Title: Impotence treatment apparatus with energy transforming means
Inventor: FORSELL PETER
IPC: A61F5/41
Filed: 2001-02-09
Granted: 2003-05-29
Abstract: A male sexual impotence treatment apparatus includes or use an operable restriction device implantable in a male patient for engaging a tissue portion of the penile tissue to form a restrictable passageway for the penile exit blood flow. An energy transmission device is provided for wireless transmission of energy from outside the patient's body to inside the patient's body for use in connection with the operation of the restriction device, including temporarily contracting said tissue portion to restrict the penile exit blood flow in the blood flow passageway to achieve erection.
Patent AU-597198-B2 (AU)
Title: Anticalculus oral compositions
Inventor: CARTER PETER
IPC: A61P1/02
Filed: 1989-02-27
Granted: 1990-05-24
Abstract: The disclosure relates to a toothpaste for inhibiting the formation of dental calculus comprising an abrasive agent and an amount of tetrapyrophosphate salt sufficient to provide at least 2.5% P2O7<4><->, which toothpaste is characterised by having a pH of at least 7.6 which rises by at least 0.45 on dilution of the toothpaste with distilled carbon-dioxide free water in the proportion of 10g of toothpaste to 30ml of water.
Patent AU-713336-B2 (AU)
Title: Biocompatible optically transparent polymeric material based upon collagen and method of making
Inventor: FEINGOLD VLADIMIR
IPC: C08H1/06
Filed: 1995-07-21
Granted: 1999-12-02
Abstract: The present invention is biocompatible polymer containing the copolymerization product of a mixture of hydrophobic and hydrophilic acrylic and/or allelic monomers, graft-polymerized with telo-collagen. The present material is useful in the production of deformable lenses, for example, intraocular lenses, refractive intraocular contact lenses, and standard contact lenses useful, for example, for correcting aphekia, myopia and hypermetropia.