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24468920 | objective | Sudden gains have been shown to predict better long-term improvement in several treatment studies , including cognitive behavioural therapy for depression and anxiety disorders , but have not been studied in the treatment of health anxiety or any form of internet-based cognitive behavioural therapy . | 1 |
24468920 | objective | The aim of this study was to investigate the role of sudden gains in internet-based cognitive behavioural therapy for severe health anxiety . | 2 |
24468920 | methods | We examined the occurrence and significance of sudden gains in measures of health anxiety in @ participants receiving internet-based cognitive behavioural therapy . | 3 |
24468920 | methods | We compared patients with sudden gains , patients without sudden gains , and patients with gradual gains . | 4 |
24468920 | results | Thirteen participants ( @ % ) experienced one sudden gain in health anxiety with individual sudden gains distributed across the treatment . | 5 |
24468920 | results | As expected , patients with a sudden gain showed larger improvements than patients without a sudden gain at post-treatment ( d = @ ) and at one-year follow-up ( d = @ ) on measures of health anxiety . | 6 |
24468920 | conclusions | Consistent with previous studies , sudden gains in internet-based cognitive behavioural therapy are associated with significantly larger and stable treatment effects up to one-year follow-up . | 7 |
25534310 | background | Same-sex attracted young adults have been found to experience higher rates of mental health problems and greater difficulties in accessing specialist mental health care services compared to their heterosexual peers . | 0 |
25534310 | background | Internet-based mental health interventions have the potential to be more engaging and accessible to young adults compared to those delivered face-to-face . | 1 |
25534310 | background | However , they are rarely inclusive of lesbian women and gay men . | 2 |
25534310 | background | Thus , the current study aims to evaluate the effectiveness of an online mental health and wellbeing program , Out & Online ( http://www.outandonline.org.au ) , in comparison to a wait-list control group , for reducing anxiety and depressive symptoms in same-sex attracted young adults aged between @ and @ years . | 3 |
25534310 | methods | We are recruiting , through media and community organisations , @ same-sex attracted young adults with anxiety and/or depressive symptoms and mild to moderate psychological distress ( Kessler-@ score between @ to @ ) . | 4 |
25534310 | methods | Participants will be randomly allocated to the intervention ( the online program ) or the wait-list control group based on a permuted blocked randomisation method to allow for stratification by gender . | 5 |
25534310 | methods | Participants in the intervention group will receive a tailored program for up to three types of mental health difficulties simultaneously . | 6 |
25534310 | methods | The primary outcome of anxiety and/or depressive symptoms , and secondary outcomes related to psychological distress , wellbeing and health behaviour will be measured at pre-intervention ( @ week ) , post-intervention ( @ weeks ) and at a @-month follow-up ( @ weeks ) . | 7 |
25534310 | conclusions | This online mental health and wellbeing program will be one of the first online interventions to be designed specifically to be relevant for same-sex attracted individuals . | 8 |
25534310 | conclusions | If the program is found to be effective it will improve access to specialist same-sex attracted-relevant mental health services for young adults and will facilitate wellbeing outcomes for these individuals . | 9 |
25534310 | conclusions | This program will also be a significant development in the delivery of tailored interventions that target multiple types of mental health conditions simultaneously . | 10 |
24996447 | background | Endometriosis affects fertility negatively . | 0 |
24996447 | background | The study aims to evaluate whether laparoscopic surgery combined with oral contraceptive or herbs were more effective than laparoscopic alone in improving fecundity and pelvic pain in women with minimal/mild endometriosis . | 1 |
24996447 | methods | A randomized controlled trial ( RCT ) was conducted in @ infertile women with minimal/mild endometriosis . | 2 |
24996447 | methods | After laparoscopic surgery , patients were randomized to three groups : in Group A ( n = @ ) oral contraceptive ( OC ) was administered one pill a day , continuous for @days without intervals , in Group B ( n = @ ) OC was administered as above and then Dan ' e mixture was added @g/day for the latter @days , and in control Group C ( n = @ ) patients tried to get pregnant after surgery without complementary treatment . | 3 |
24996447 | methods | The follow-up periods were @months in Group C and @months in complementary medical treatment Group A and B. | 4 |
24996447 | methods | The pregnant women were further followed up , and labor and pregnancy outcomes were assessed . | 5 |
24996447 | methods | Primary outcome was pregnancy rate ( PR ) and live birth rate ( LBR ) . | 6 |
24996447 | methods | Secondary outcomes included changes of pelvic pain visual analog scale scores and side effects . | 7 |
24996447 | methods | Analyses were done as intention-to-treat . | 8 |
24996447 | results | The PR was @ % ( @/@ ) , and the LBR was @ % ( @/@ ) . | 9 |
24996447 | results | Of the @ pregnancies , @ occurred within @months of follow-up and @ of the remaining @ patients underwent assisted reproductive technology for > @year . | 10 |
24996447 | results | No significant difference was observed in PR and LBR among the three groups . | 11 |
24996447 | results | Patients given medical treatment ( OCs or OCs plus herbal medicine ) had significantly decreased pain scores compared with the laparoscopy alone group . | 12 |
24996447 | conclusions | Combination of laparoscopy with OCs or OCs and herbal medicine does not have more advantages than laparoscopy alone in improving fertility of women with minimal/mild endometriosis . | 13 |
24393346 | objective | To explore the effect of continuous nursing intervention guided by chronotherapeutics so as to provide the easy , noninvasive , effective and acceptable intervention for older hypertensive patients in the community . | 0 |
24393346 | background | Many researchers studied the effect of administration at different times on blood pressure control and circadian rhythm . | 1 |
24393346 | background | However , the individual administrative time was set ambiguously in previous studies . | 2 |
24393346 | methods | A semi-experimental study . | 3 |
24393346 | methods | In the study , @ eligible patients were recruited and separated into three groups randomly , which were the control group , intervention group A ( behaviour and chronotherapy intervention ) and intervention group B ( behaviour intervention ) . | 4 |
24393346 | methods | At @ and @months after the study , the intervention groups were measured @-hour ambulatory blood pressure monitoring . | 5 |
24393346 | results | There were significant differences in ambulatory blood pressure monitoring parameters of the two intervention groups at different measurement times , and there were interaction between measurement time and different groups . | 6 |
24393346 | results | The number of patients with dipper increased and reverse dipper decreased in group A as the intervention applied . | 7 |
24393346 | results | There were statistical differences between two groups . | 8 |
24393346 | results | The number of patients with morning surge in group A decreased more , and there were statistical differences between two groups at six months after the intervention . | 9 |
24393346 | conclusions | The behaviour and chronotherapy intervention based on the patients ' ambulatory blood pressure monitoring can control casual blood pressure much better and last longer , which can also improve patients ' indexes of ambulatory blood pressure monitoring better than behaviour intervention only . | 10 |
24393346 | conclusions | The behaviour and chronotherapy intervention can increase patients ' nocturnal blood pressure drop , increase the number of patients with dipper and decrease reverse dipper , and improve blood pressure surge in the morning . | 11 |
24393346 | conclusions | Nurses can use continuous nursing intervention guided by chronotherapeutics to help improve hypertension of older patients better in the community . | 12 |
24262772 | objective | To test the impact of the method of administration ( MOA ) on score level , reliability , and validity of scales developed in the Patient Reported Outcomes Measurement Information System ( PROMIS ) . | 0 |
24262772 | methods | Two nonoverlapping parallel forms each containing eight items from each of three PROMIS item banks ( Physical Function , Fatigue , and Depression ) were completed by @ adults with chronic obstructive pulmonary disease , depression , or rheumatoid arthritis . | 1 |
24262772 | methods | In a randomized crossover design , subjects answered one form by interactive voice response ( IVR ) technology , paper questionnaire ( PQ ) , personal digital assistant ( PDA ) , or personal computer ( PC ) and a second form by PC , in the same administration . | 2 |
24262772 | methods | Method equivalence was evaluated through analyses of difference scores , intraclass correlations ( ICCs ) , and convergent/discriminant validity . | 3 |
24262772 | results | In difference score analyses , no significant mode differences were found and all confidence intervals were within the prespecified minimal important difference of @ standard deviation . | 4 |
24262772 | results | Parallel-forms reliabilities were very high ( ICC = @-@ @ ) . | 5 |
24262772 | results | Only one across-mode ICC was significantly lower than the same-mode ICC . | 6 |
24262772 | results | Tests of validity showed no differential effect by MOA . | 7 |
24262772 | results | Participants preferred screen interface over PQ and IVR . | 8 |
24262772 | conclusions | We found no statistically or clinically significant differences in score levels or psychometric properties of IVR , PQ , or PDA administration compared with PC . | 9 |
24503689 | methods | Prospective randomized study . | 0 |
24503689 | objective | This study aimed to prospectively compare the surgical results of the open - and French-door laminoplasty . | 1 |
24503689 | background | Cervical laminoplasty is a common surgical procedure for the treatment of cervical compressive myelopathy . | 2 |
24503689 | background | These procedures are primarily classified as either open - or French-door laminoplasties . | 3 |
24503689 | background | Only few prospective studies comparing the surgical results of the @ procedures are available . | 4 |
24503689 | methods | A total of @ patients with cervical compressive myelopathy who underwent cervical laminoplasty were prospectively enrolled and randomized into the following @ groups according to the type of laminoplasty : open-door and French-door groups . | 5 |
24503689 | methods | A single attending spine surgeon performed all surgical procedures . | 6 |
24503689 | methods | The following factors were evaluated : surgical duration , blood loss , perioperative complications , neurological assessment using the Japanese Orthopedic Association score , and recovery rate . | 7 |
24503689 | methods | Radiological evaluations included assessment of the cervical lordotic angle and cervical range of motion . | 8 |
24503689 | methods | In addition , the ratio of postoperative spinal lamina opening was evaluated by magnetic resonance imaging . | 9 |
24503689 | results | There were no differences in perioperative complications and neurological outcomes between the @ groups . | 10 |
24503689 | results | The mean reduction in cervical lordotic angle after surgery was significantly greater in the open-door group than the French-door group ( @ vs. @ ) . | 11 |
24503689 | results | Postoperative cervical range of motion significantly decreased in the open-door group than in the French-door group ( @ vs. @ ) . | 12 |
24503689 | results | Postoperative cervical lordotic angle in the extension position significantly diminished in the open-door group than in the French-door group ( @ vs. @ ) . | 13 |
24503689 | results | The ratio of opening of the spinal lamina after surgery was significantly larger in the open-door group than in the French-door group . | 14 |
24503689 | conclusions | The @ laminoplasty methods showed almost the same neurological recovery as well as perioperative complications . | 15 |
24503689 | conclusions | In cases of open-door laminoplasty , postoperative cervical alignment became more kyphotic and cervical range of motion was more restricted than that in French-door laminoplasty cases after surgery . | 16 |
24503689 | conclusions | French-door laminoplasty is preferable to open-door laminoplasty for postoperative cervical alignments . | 17 |
24648359 | background | Burnout is a very prevalent type of stress among health professionals . | 0 |
24648359 | background | It affects their well-being , performance , and attitude toward patients . | 1 |
24648359 | background | This study assessed the effectiveness of a training program for primary health care professionals designed to reduce burnout and mood disturbance , increase empathy , and develop mindfulness . | 2 |
24648359 | methods | Pragmatic randomized controlled trial with pre - and postintervention measurements of @ primary health care professionals ( @ in the intervention and @ in the control group ) in Spain . | 3 |
24648359 | methods | The intervention consisted of presentations of clinically relevant topics , mindfulness-based coping strategies , mindfulness practice , yoga , and group discussions ( @ sessions of @ hours per week plus a @-day session of @ hours ) . | 4 |
24648359 | methods | Outcome measures included the Maslach Burnout Inventory , Profile of Mood States , Jefferson Scale of Physician Empathy , Baer 's Five Facets Mindfulness Questionnaire , and a questionnaire on changes in personal habits and mindfulness practice . | 5 |
24648359 | methods | Measurements were performed at baseline and after @ weeks . | 6 |
24648359 | results | The intervention group improved in the @ scales measured . | 7 |
24648359 | results | The magnitude of the change was large in total mood disturbance ( difference between groups -@ ; standardized effect-size -LSB- SES -RSB- @ ) and mindfulness ( difference between groups @ ; SES @ ) and moderate in the burnout ( difference between groups -@ ; SES @ ) and empathy scales ( difference between groups @ ; SES @ ) . | 8 |
24648359 | results | No significant differences were found in the control group . | 9 |
24648359 | conclusions | Our study supports the use of mindfulness-based programs as part of continuing professional education to reduce and prevent burnout , promote positive attitudes among health professionals , strengthen patient-provider relationships , and enhance well-being . | 10 |
25922903 | objective | Anogenital warts are a common disorder associated with significant physical and mental distress and a substantial cause of health care costs . | 0 |
25922903 | objective | To assess the efficacy of the topical application of nitric oxide delivered using acidified nitrite . | 1 |
25922903 | methods | A multicenter , randomized , controlled , dose-ranging clinical trial was conducted in European genitourinary medicine clinics between December @ , @ , and January @ , @ . | 2 |
25922903 | methods | Analysis was by intent to treat for all individuals initiating therapy . | 3 |
25922903 | methods | Participants included male and female volunteers older than @ years with between @ and @ external anogenital warts . | 4 |
25922903 | methods | A total of @ individuals from @ centers were randomized to a control arm and a treatment arm that received @ doses of acidified nitrite applied topically for @ weeks with an additional @ weeks of follow-up , with the final follow-up visit on January @ , @ . | 5 |
25922903 | methods | Placebo nitrite cream and placebo citric acid cream were applied twice daily . | 6 |
25922903 | methods | Active treatment was divided as low dose ( sodium nitrite , @ % , with citric acid , @ % , creams applied twice daily ) , middle dose ( sodium nitrite , @ % , with citric acid , @ % , creams applied once daily at night , with placebo applied in the morning ) , and high dose ( sodium nitrite , @ % , with citric acid , @ % , creams applied twice daily ) . | 7 |
25922903 | methods | The primary outcome was proportion of patients with complete clinical clearance of target warts ; secondary outcomes were reduction in target wart area and safety . | 8 |
25922903 | results | Complete clinical clearance at @ weeks occurred in @ of @ patients ( @ % ; @ % CI , @ % -@ % ) with placebo ; @ of @ ( @ % ; @ % CI , @ % -@ % ) with low-dose treatment ; @ of @ ( @ % ; @ % CI , @ % -@ % ) with middle-dose treatment ; and @ of @ ( @ % ; @ % CI , @ % -@ % ) with high-dose treatment ( P = @ ) . | 9 |
25922903 | results | Reduction in target wart area , time to clearance , and patient and investigator assessments supported the superiority of the high-dose therapy vs placebo . | 10 |
25922903 | results | There were no systemic or serious adverse events associated with treatment . | 11 |
25922903 | results | However , there was a dose-related increase in itching , pain , edema , and staining of the anogenital skin associated with the active treatment . | 12 |
25922903 | results | Overall , @ patients withdrew from active treatment because of adverse events compared with none using placebo . | 13 |
25922903 | conclusions | Use of sodium nitrite , @ % , with citric acid , @ % , twice daily is more effective than placebo in the treatment of anogenital warts . | 14 |
25922903 | conclusions | Treatment was associated with local irritant adverse effects . | 15 |