ahmedabdelwahed/Medical_papers_title_and_abstract_NLP_dataset huggingface dataset:
Seasonal characteristics of biogenic secondary organic aerosol tracers in a deciduous broadleaf forest in northern Japan

We collected total suspended particulate (TSP) samples from January 2010 to December 2010 at Sapporo deciduous forest to understand the oxidation processes of biogenic volatile organic compounds (BVOCs). The gas chromatography-mass spectrometric technique was applied to determine biogenic secondary organic aerosols (BSOAs) in the TSP samples. We found the predominance of the isoprene SOA (iSOA) tracers (20.6 ng m-3) followed by α/β-pinene SOA (pSOA) tracers (8.25 ng m-3) and β-caryophyllene SOA (cSOA) tracer (1.53 ng m-3) in the forest aerosols. The results showed large isoprene fluxes and relatively high levels of oxidants in the forest atmosphere. The iSOA and pSOA tracers showed a clear seasonal trend with summer and autumn maxima and winter and spring minima. Their seasonal trends were mainly controlled by BVOCs emission from the local broadleaf deciduous forest. Additionally, the regional level of isoprene emissions from the oceanic sources may also be contributed during summertime aerosols. cSOA tracer showed high concentrations in the winter and spring, possibly due to an additional contribution of biomass burning (BB) aerosols from the local or regional BB activities. The biogenic secondary organic carbon (BSOC) was contributed mainly by the oxidation products of isoprene (136 ngC m-3) followed by β-caryophyllene (63.0 ngC m-3) and α/β-pinene (35.9 ngC m-3). The mass concentration ratio (0.92) of pinonic acid + pinic acid and 3-methyl-1,2,3-butanetricarboxylic acid ((PNA + PA)/3-MBTCA) indicates the photochemical transformation of first-generation oxidation products to the higher generation oxidation products. The average ratios of isoprene to α/β-pinene (1.64) and β-caryophyllene (18.6) oxidation products suggested a large difference in the emissions of isoprene and α/β-pinene compared to β-caryophyllene. The cSOA tracers in the forest aerosols are also contributed by BB during the winter and spring. Positive matrix factorization analyses of the BSOA tracers confirmed that organic aerosols of deciduous forests are mostly related to isoprene emissions. This study suggests that isoprene is a more significant precursor for the BSOA than α/β-pinene and β-caryophyllene in a broadleaf deciduous forest.
Trim69 is a microtubule regulator that acts as a pantropic viral inhibitor

Through a screen that combines functional and evolutionary analyses, we identified tripartite motif protein (Trim69), a poorly studied member of the Trim family, as a negative regulator of HIV-1 infection in interferon (IFN)-stimulated myeloid cells. Trim69 inhibits the early phases of infection of HIV-1, but also of HIV-2 and SIVMAC in addition to the negative and positive-strand RNA viruses vesicular stomatitis virus and severe acute respiratory syndrome coronavirus 2, with magnitudes that depend on the combination between cell type and virus. Mechanistically, Trim69 associates directly to microtubules and its antiviral activity is linked to its ability to promote the accumulation of stable microtubules, a program that we uncover to be an integral part of antiviral IFN-I responses in myeloid cells. Overall, our study identifies Trim69 as the antiviral innate defense factor that regulates the properties of microtubules to limit viral spread and highlights the cytoskeleton as an unappreciated battleground in the host-pathogen interactions that underlie viral infections.
Partially Reduced MIL-100(Fe) as a CO Carrier for Sustained CO Release and Regulation of Macrophage Phenotypic Polarization

Carbon monoxide (CO) is a bioactive molecule with high potential as it shows promising efficacy for regulating inflammation. Materials capable of storing and delivering CO are of great potential therapeutic value. Although CO-releasing molecules (CORMs) have been developed to deliver CO, the short CO duration of minutes to 2 h confines their practical use. In this study, partially reduced MIL-100(Fe) as a new CO-releasing nanoMOF was developed and used for sustained CO release and macrophage (MA) phenotypic polarization regulation. MIL-100(Fe) was synthesized and mildly annealed in vacuum for partial reduction. When the annealing temperature was lower than 250 °C, less Fe(II) present in MIL-100(Fe) and the subsequent CO adsorption and desorption profiles displayed typical features of physisorption. While it was annealed at 250 °C, it showed about 20% of Fe(III) was reduced, which resulted in chemisorption of CO due to the high coordination affinity of Fe(II) to CO. The loading amount of CO was increased, and the CO release was prolonged for about 24 h. Furthermore, the CO release from this nanoMOF could alter the lipopolysaccharide (LPS)-induced macrophage from M1 to the alternative M2 phenotype and promoted the growth of endothelial cells (ECs) by paracrine regulation of MA. It can be envisioned as a promising CO-releasing solid for biomedical application.
A WD-RANSAC Instantaneous Frequency Estimator

AWigner distribution-based random sample consensus (RANSAC) algorithm for the instantaneous frequency estimation is proposed. The algorithm performance is studied for several signal types and compared with the state-of-the-art Viterbi algorithm in both accuracy and complexity.
Enhanced Embedding Capacity for Data Hiding Approach Based on Pixel Value Differencing and Pixel Shifting Technology

Data hiding algorithms can achieve the issue of information security when secret data are transmitted via the public network. This paper proposes a novel data-hiding scheme based on pixel value differencing and pixel shifting to increase embedding capacity and visual quality. In the proposed method, the cover image is first divided into nonoverlapping blocks, and eight groups of different values are generated with the center pixel as the reference pixel to embed the secret message. The pixel shifting strategy is applied to adjust the stego image to improve its quality. Experimental results show that the proposed method has an embedding capacity of 740,000 bits with a peak signal-to-noise ratio value greater than 35 dB. Therefore, it is undetected by the human eye. Other compared state-of-the-art schemes have embedding capacities of 51,219 bits, 70,217 bits, and 104,055 bits, which are lower than the proposed methods' 740,000 bits. The RS, chi-square, and rotation attack analyses prove that the proposed method can withstand security attacks. Thus, the proposed method performs better than other state-of-the-art methods with respect to embedding capacity and ability to withstand attacks.
Martial Arts Tourism: Meta-Analysis of Publications from 2005-2020

A feature of modern society in the era of cultural globalization is its mobility. One of the manifestations of this social mobility is people spending free time on tourist trips. Tourism, as understood as a sociocultural phenomenon, is a special manifestation of location. In addition to the motives for undertaking trips in martial arts tourism, individual destinations, specific tourism potential and the typology of participants in tourist meetings were analyzed, and individual cases were examined. The research materials were 44 articles published in scientific journals indexed inScopus,Web of Science, andEBSCOHostdatabases. Publications, which appeared in the sources discussed between 2005 and mid-2020s were considered. Some periodicals were present in all three of the quoted databases, therefore specific articles were taken into account only once. This study will cover a meta-analysis of martial arts tourism in journals indexed in several major scientific databases. It is related to the phenomenon of tourism of this type, which is discussed from various scientific perspectives. As a research tool, the Atlas.ti program was used (mainly in the qualitative research or analysis of qualitative data), by means of which correlations and dominant items were sought. A comparison with other publications suggests that no similar meta-analysis has so far been performed in relation to the literature devoted to the subject of "martial arts tourism". Particularly interesting conclusions were identified: (1) there are thematic relations between the destination country, the main destination, and the destination country; (2) martial arts are treated by researchers as both primary, and secondary threads, (3) the difference between travel destinations and types events attended by people interested in martial arts, (4) the variety of event formats plays a role in popularizing the subject of these forms of physical activity, and (5) the number of publications describing specific destinations is not particularly related to specific countries as destinations.
Detection at high prevalence of newlavirus (protoparvovirus) in the carcasses of red foxes

Wildlife conservation also relies on the study of animal virome. We identified the DNA of a novel fox protoparvovirus, newlavirus, with high (71%) prevalence in the carcasses of red foxes. On genome sequencing, high genetic diversity and possible recombination was observed, suggesting complex evolutionary dynamics in wildlife.
Life cycle assessment and techno-economic analysis of nitrogen recovery by ammonia air-stripping from wastewater treatment

Wastewater treatment plants (WWTPs) with anaerobic digestion of biosolids produce an ammonia-rich sidestream out of which nitrogen can be recovered through air stripping. Recovered ammonia can be used to produce ammonium sulfate (AS) for agricultural use, enabling the circular return of nitrogen as fertilizer to the food system. We investigate the cost and life cycle environmental impact of recovering ammonia from the sidestream of WWTPs for conversion to AS and compare it to AS production from the Haber Bosch process. We perform life cycle assessment (LCA) to investigate the environmental impact of AS fertilizer production by air-stripping ammonia from WWTP sidestreams at varying sidestream nitrogen concentrations. Techno-economic analysis (TEA) is performed to assess the break-even selling price of sidestream AS production at a WWTP in the City of Philadelphia. Greenhouse gas emissions for air-stripping technology range between 0.2 and 0.5 kg CO2e/kg AS, about six times lower than the hydrocarbon-based Haber-Bosch process, estimated at 2.5 kg CO2e/kg AS. Further reduction of greenhouse gas emissions is feasible by replacing fossil-based energy use in air-stripping process (82-98 % of net energy demand) with renewable sources. Also, a significant reduction in mineral depletion and improvement in human and ecosystem health are observed for the air-stripping approach. Furthermore, the break-even selling price for installing sidestream-based AS production at the Philadelphia's WWTP, considering capital and operating costs, is estimated at $0.046/kg AS (100 %), which is 92 % lower than the 2014 estimate of AS's average selling price at farms in the United States. We conclude that even with varying ammonia concentrations and high sidestream volume, air-stripping technology offers an environmentally and economically favorable option for implementing nitrogen recovery and simultaneous production of AS at WWTPs.
Divergence-Free Constrained Phase Unwrapping and Denoising for 4D Flow MRI Using Weighted Least-Squares

A novel divergence-free constrained phase unwrapping method was proposed and evaluated for 4D flow MRI. The unwrapped phase field was obtained by integrating the phase variations estimated from the wrapped phase data using weighted least-squares. The divergence-free constraint for incompressible blood flow was incorporated to regulate and denoise the resulting phase field. The proposed method was tested on synthetic phase data of left ventricular flow and in vitro 4D flow measurement of Poiseuille flow. The method was additionally applied to in vivo 4D flow measurements in the thoracic aorta from 30 human subjects. The performance of the proposed method was compared to the state-of-the-art 4D single-step Laplacian algorithm. The synthetic phase data were completely unwrapped by the proposed method for all the cases with velocity encoding (venc) as low as 20% of the maximum velocity and signal-to-noise ratio as low as 5. The in vitro Poiseuille flow data were completely unwrapped with a 60% increase in the velocity-to-noise ratio. For the in-vivo aortic datasets with venc ratio less than 0.4, the proposed method significantly improved the success rate by as much as 40% and reduced the velocity error levels by a factor of 10 compared to the state-of-the-art method. The divergence-free constrained method exhibits reliability and robustness on phase unwrapping and shows improved accuracy of velocity and hemodynamic quantities by unwrapping the low-venc 4D flow MRI data.
Fractional-N Phase-Locked-Loop-Based Frequency Synthesis: A Tutorial

The fundamentals and state of the art in fractional-N phase-locked-loop (PLL)-based frequency synthesis are reviewed. Particular emphasis is placed on delta-sigma fractional-N PLLs and quantization noise and fractional spur suppression techniques for wide-bandwidth applications.
Demonstration of Constant 8 W/mm Power Density at 10, 30, and 94 GHz in State-of-the-Art Millimeter-Wave N-Polar GaN MISHEMTs

This paper reports on state-of-the-art millimeter-wave power performance of N-polar GaN-based metal-insulator-semiconductor high-electron-mobility transistors at 30 and 94 GHz. The performance is enabled by our N-polar deep recess structure, whereby a GaN cap layer is added in the access regions of the transistor to simultaneously enhance the access region conductivity while mitigating dc-to-RF dispersion. The impact of lateral scaling of the drain access region length is examined using the tradeoff between breakdown voltage and small-signal gain. Load-pull measurements are presented at 94 GHz, corresponding to the target device operating frequency in W-band, where the device demonstrated a peak power-added efficiency (PAE) of 28.8% at 16 V and record-high maximum output power density of 8 W/mm at 20 V. Additional load-pull measurements at 30 and 10 GHz demonstrate the viability of this device across a wide frequency range where the peak power remained constant at 8W/mm and with peak PAEs of 56% and 58%, respectively.
Chinese Destinations Related to Martial Arts Tourism from the UNESCO Perspective

The aim of this article is to investigate the authenticity of Shaolin Temple and Chenjiagou Village in the context of intensified martial arts tourism and UNESCO documents. Desk research, structured interviews and participant observation were used to investigate the issue. The issue of cultural and natural heritage has become part of the modern image of a powerful new China. They particularly use these resources in cultural tourism, where boasting of heritage listed on UNESCO's tangible and intangible heritage list is certainly an appropriate impression. The UNESCO intangible and tangible heritage list also includes objects related to martial arts tourism (Shaolin Temple, Chenjiagou Village). The article presents how Western (American, European) preferences and expectations are visible in the way of preserving and using these objects with an attempt to maintain UNESCO standards. It has been noticed that the added objects/events/shows are accepted by the Chinese as increasing the attractiveness of the place, even if they are not thematically and historically related to it. The authors checked whether a certain cultural compromise is possible or whether these places are a completely Westernized product, taking the form of theme parks or ethnoparks. For Western tourists, such phenomena are often synonymous with the commercialization and falsification of the authenticity of a place, which is why the role of cultural education is very important, both in China and in Western countries.
Meta-analysis for Association of Interleukin 4 VNTR Polymorphism with Rheumatoid Arthritis Risk and Severity

Rheumatoid Arthritis (RA) is a chronic autoimmune disease characterized by severe joint pain. There are conflicting results for the association of Interleukin 4 (IL4) variable number tandem repeats (VNTR; rs8179190) polymorphism with RA. Therefore, we performed a meta-analysis of the available studies to investigate the association of IL4 VNTR polymorphism with RA risk and severity in the overall populations and Asian, Egyptian, European, and Turkish ethnicities by sub-group analyses. Eight studies involving 1993 RA patients and 1732 controls were included in this meta-analysis. We found increased RA risk for the susceptible "R2R2" genotype and "R2" allele under heterozygous, recessive, and allelic models in the Asian populations (p < 0.00001, p < 0.0001, p = 0.001). We observed a significant association between "R2R2" genotype and "R2" allele for RA protection in the Turkish population under heterozygous, recessive, and allelic models (p = 0.01, p = 0.004, p = 0.002). Disease severity-based analysis revealed significant association for "R2R2" genotype and "R2" allele with RA severity under homozygous, heterozygous, recessive, dominant, and allelic models(p = 0.0004, p = 0.03, p = 0.02, p = 0.003, p = 0.01), specifically in Asian populations (p = 0.009, p = 0.02, p = 0.003, p = 0.03, p = 0.01) and under heterozygous, dominant, and allelic genetic models in Egyptian (p = 0.0001, p < 0.0001, p < 0.0001) and European (p = 0.002, p = 0.0007, p = 0.0006) populations. In silico analysis suggested that the susceptible "R2" allele changes the RNA secondary structure to a stable form by changing minimum free energy(ΔG) from - 115.20 to - 136.40 kcal/mol, which might lead to increased stability of IL-4 in RA patients. Overall, the meta-analysis suggests for the involvement of susceptible "R2" allele with RA risk in the Asian populations, RA severity in the overall populations (specifically in Asian, Egyptian, & European populations), and RA protection in the Turkish population.
Learning about climate change in, with and through art

Effective strategies to learn about and engage with climate change play an important role in addressing this challenge. There is a growing recognition that education needs to change in order to address climate change, yet the question remains "how?" How does one engage young people with a topic that is perceived as abstract, distant, and complex, and which at the same time is contributing to growing feelings of sadness, hopelessness, and anxiety among them? In this paper, I argue that although the important contributions that the arts and humanities can make to this challenge are widely discussed, they remain an untapped or underutilized potential. I then present a novel framework and demonstrate its use in schools. Findings from a high school in Portugal point to the central place that art can play in climate change education and engagement more general, with avenues for greater depth of learning and transformative potential. The paper provides guidance for involvementin,with, andthroughart and makes suggestions to create links between disciplines to support meaning-making, create new images, and metaphors and bring in a wider solution space for climate change. Going beyond the stereotypes of art as communication and mainstream climate change education, it offers teachers, facilitators, and researchers a wider portfolio for climate change engagement that makes use of the multiple potentials of the arts.
ART-MMAP: A neural network approach to subpixel classification

Global or continental-scale land cover mapping with remote sensing data is limited by the spatial characteristics of satellites. Subpixel-level mapping is essential for the successful description of many land cover patterns with spatial resolution of less than similar to1 km and also useful for finer resolution data. This paper presents a novel adaptive resonance theory MAP (ARTMAP) neural network-based mixture analysis model-ART mixture MAP (ART-MMAP). Compared to the ARTMAP model, ART-MMAP has an enhanced interpolation function that decreases the effect of category proliferation in ART, and overcomes the limitation of class category in ART(b). Results from experiments demonstrate the superiority of ART-MMAP in terms of estimating the fraction of land cover within a single pixel.
Respecting local knowledge keepers through cellphilms featuring local water bodies: towards decolonizing water management

This paper outlines arts-based methods aimed at exploring how storytelling with local knowledge keepers (KKs) through cellphilms featuring local waterways might contribute to decolonizing water management by uncovering different values of and relationships with water. We define knowledge keepers' as people who have an existing relationship with a particular water body and whose knowledge and expertise with respect to the water body emerge from lived experience and not academic scholarship or technical training. We provide insights into and analyse a graduate curriculum enacted in South Africa, where students, through encounters with local KKs and water bodies, made cellphilms presenting their own water narratives and screened these for the public. Cellphilms, participatory visual methods in research and teaching, are used to explore learning experiences for students and KKs, and the resulting cellphilms become places of knowledge transfer. We outline our theoretical and methodological approaches as they relate to our goals of decolonizing expertise in higher education learning and addressing multiple types of water-related values.
Identification, molecular characterization and gene expression analysis of sox1a and sox1b genes in Japanese flounder, Paralichthys olivaceus

The transcription factor, Sox1 has been implicated in neural determination and differentiation as well as in the maintenance of neural progenitor cell status in mammals. However, the molecular cloning and expression of sox1 gene in marine fish have not been reported yet. In this study, we first cloned and characterized the full-length cDNAs and the partial 5'-flanking regions of Paralichthys olivaceus sox1a (Posox1a) and sox1b (Posox1b). Phylogenetic, gene structure, and chromosome synteny analyses revealed that Posox1a and Posox1b were co-orthologs and homologous to mammalian Sox1. The promoter regions of Posox1a and Posox1b were also analyzed and several potential transcription factor (TF) binding sites were identified which might modulate gene expression. Quantitative real-time RT-PCR (qRT-PCR) results showed that Posox1a and Posox1b were consistently expressed during embryogenesis, with the highest level at the neurula stage. Tissue distribution analyses revealed that Posox1a and Posox1b were abundant in the adult brain. Moreover, Posox1a had a faster evolution rate and much higher expression levels than Posox1b. These results provide a foundation for further surveying the function of PoSox1 genes during Japanese flounder development and neurogenesis.