ahmedabdelwahed/Medical_papers_title_and_abstract_NLP_dataset huggingface dataset:
Molecular analysis of genes involved in chitin degradation from the chitinolytic bacterium Bacillus velezensis

Bacillus velezensis RB.IBE29 is a potent biocontrol agent with high chitinase activity isolated from the rhizosphere of black pepper cultivated in the Central Highlands, Vietnam. Genome sequences revealed that this species possesses some GH18 chitinases and AA10 protein(s); however, these enzymes have not been experimentally characterized. In this work, three genes were identified from the genomic DNA of this bacterium and cloned in Escherichia coli. Sequence analysis exhibited that the ORF of chiA consists of 1,203 bp and encodes deduced 45.46 kDa-chitinase A of 400 aa. The domain structure of chitinase A is composed of a CBM 50 domain at the N-terminus and a catalytic domain at the C-terminus. The ORF of chiB includes 1,263 bp and encodes deduced 47.59 kDa-chitinase B of 420 aa. Chitinase B consists of two CBM50 domains at the N-terminus and a catalytic domain at the C-terminus. The ORF of lpmo10 is 621 bp and encodes a deduced 22.44 kDa-AA10 protein, BvLPMO10 of 206 aa. BvLPMO10 contains a signal peptide and an AA10 catalytic domain. Chitinases A and B were grouped into subfamily A of family 18 chitinases. Amino acid sequences in their catalytic domains lack aromatic residues (Trp, Phe, Tyr) probably involved in processivity and substrate binding compared with well-known bacterial GH18 chitinases. chiB was successfully expressed in E. coli. Purified rBvChiB degraded insoluble chitin and was responsible for inhibition of fungal spore-germination and egg hatching of plant-parasitic nematode. This is the first report describing the analysis of the chitinase system from B. velezensis.
Occam's Razor and Managing Acute Thrombosis in the COVID-19 Era

The COVID-19 pandemic has profoundly influenced the practice of medicine in Australia over the last 24 months. Recently, the development of several vaccines to COVID-19 has been accompanied by reports of an associated rare syndrome of thrombosis and thrombocytopaenia (VITTS). The possibility of this rare disorder confronts all clinicians who deal with acute thrombosis, particularly given the prevalence of patients who have recently been immunised. However, VITTS remains rare, and we believe unnecessary focus on its potential diagnosis may distract from other more common causes of acute thrombosis. We discuss this with reference to a recent case at our institution.
Phelypaeaboissierif.lutea (Orobanchaceae), a peculiar new form from Turkey and typification of the name of this species

The genus Phelypaea includes three holoparasite species with one of the most intense red flowers among all plants worldwide. So far, there are few references to other colour taxa of this genus. We describe a new yellow-coloured form, Phelypaeaboissierif.lutea, from Hakkari province in the Cilo Mountains of SE Turkey, found at an altitude of 2,470 m. In typical P.boissieri, here typified by us, the flowers are deeply red, and stems, calyx and scales are red to brown, or rarely pale-brown, whereas in the entire population of f.lutea the corolla, calyx, and scales are yellow to orange with black folds in the corolla, while only the stem is brownish.
Digestate management in polish farms as an element of the nutrient cycle

The work aims to examine and discuss the fertilizing properties of digestate (digested pulp) from three different agricultural biogas plants in terms of the substrates used. Based on the market prices of fertilizers, the economic value of the digestate has been assessed. For a selected biogas plant, the economic balance has been calculated, taking into account the income resulting from the sale of the digestate. The results obtained allow for stating that samples of digestate were rich in nitrogen (up to 6.58 g kg(-1)), and potassium (up to 16.3 g kg(-1)) in fresh matter (FM). The value of the digestate for installations was estimated in the range of 6.08-15.36 EUR.Mg-1. The analysis for one of the 1MW biogas plants shows that under current conditions of supporting systems, the daily income for a biogas plant is 1,414 EUR and the digestate produced is worth another 334.4 EUR. Its application, especially on fields adjacent to biogas plants, is part of the principle of nutrient recovery in the circular economy. (c) 2019 Elsevier Ltd. All rights reserved.
The political economy of coal in Poland: Drivers and barriers for a shift away from fossil fuels

Poland is the largest hard coal and second largest lignite producer in the EU, generating around 80 percent of its electricity from coal. Resistance to a reduction in coal production and consumption comes from various actors, namely, coal corporations, unions, parts of civil society and the government - as well as their coalitions. Their opposition centres around the prospect of losing their business, past negative experiences with structural change, fears of rising energy prices and energy security concerns, as well as potential unemployment in regions almost entirely dependent on coal. This paper identifies key political and economic drivers and barriers of a reduction in coal production and consumption in Poland using the Triple Embeddedness Framework. Uneconomic coal mining, unavoidable energy infrastructure investments, rising air pollution levels and pressure from the European Union might provide new political momentum for a shift away from coal in line with international climate targets. However, results show that to achieve political feasibility, policies targeting a reduction in coal production and use need to be implemented jointly with social and structural policy measures, addressing a just transition for the affected regions in line with the vision of a 'European Green Deal'.
Coordinated wind-thermal-energy storage offering strategy in energy and spinning reserve markets using a multi-stage model

Renewable energy resources such as wind, either individually or integrated with other resources, are widely considered in different power system studies, especially self-scheduling and offering strategy problems. In the current paper, a three-stage stochastic multi-objective offering framework based on mixed-integer programming formulation for a wind-thermal-energy storage generation company in the energy and spinning reserve markets is proposed. The commitment decisions of dispatchable energy sources, the offering curves of the generation company in the energy and spinning reserve markets, and dealing with energy deviations in the balancing market are the decisions of the proposed three-stage offering strategy problem, respectively. In the suggested methodology, the participation model of the energy storage system in the spinning reserve market extends to both charging and discharging modes. The proposed framework concurrently maximizes generation company's expected profit and minimizes the expected emission of thermal units applying lexicographic optimization and hybrid augmented-weighted is an element of-constraint method. In this regard, the uncertainties associated with imbalance prices and wind power output as well as day-ahead energy and spinning reserve market prices are modeled via a set of scenarios. Eventually, two different strategies, i.e., a preference-based approach and emission trading pattern, are utilized to select the most favored solution among Pareto optimal solutions. Numerical results reveal that taking advantage of spinning reserve market alongside with energy market will substantially increase the profitability of the generation company. Also, the results disclose that spinning reserve market is more lucrative than the energy market for the energy storage system in the offering strategy structure.
Economics of energy and environmental efficiency: evidence from OECD countries

The purpose of this research is to determine the efficiency of energy usage and its role in carbon dioxide emissions (CI) and economic-environmental efficiency (EEE) for some countries Organization for Economic Co-operation and Development (OECD) economies. For environment quality assessment, data envelopment analysis (DEA) is used to assess the data cover the period from 2013 to 2017. In this study, primary energy consumption (PEC) and population are two basic inputs along with gross domestic product (GDP) and carbon dioxide emissions that are desirable and undesirable outputs, respectively. The practical outcomes illustrate that Brunei, Australia, Singapore, and Hong Kong are the most effective and efficient states for the 5 years periods (2013-2017) in terms of energy efficiency and to reduce emission of carbon dioxide. In addition, other states in the OECD region shows greater economic proficiency than environmental proficiency. Furthermore, the results shows that energy efficiency has strong bonding with carbon emissions; however there is a weaker association between economic environmental efficiency. Thus, the attainment of optimal level of energy efficiency could be more pivotal than economic efficiency to improve environmental efficiency in countries from the OECD region.
Total Knee Arthroplasty for Osteoarthritis in a Patient with Nail Patella Syndrome - A Case Report

Hereditary osteo-onychodysplasia (or nail patella syndrome) is a rare autosomal dominant disease defined by an association of severe characteristics, with a classic clinical tetrad of dysplasia of the fingernails, patellar hypoplasia or absence, presence of iliac horns, and deformities of the elbow, although renal, ocular and neurological involvement may also be present. The main orthopedic complaint of these patients is patellar instability associated with pain and functional limitation. Most of the literature regarding the treatment of NPS-related patellar problems, concerns pediatric population and there is no treatment algorithm defined for adult patients. NPS has a wide range of presentations in skeletally mature patients, and its severity is also very variable. The general practitioner should be familiar with NPS's clinical presentation spectrum, and the orthopedic surgeon with treatment options, in order to provide the most adequate treatment for each patient. Although there is no cure for NPS, several treatments have been useful in the symptomatic treatment of changes in the knees. We describe a rare clinical case of a 47-year-old female patient with NPS who underwent total knee arthroplasty for knee osteoarthritis.
Recent developments in the passive and hybrid thermal management techniques of lithium -ion batteries

The main obstacle in the transition from petrol/diesel vehicles to electric vehicles (EVs) is the performance of power battery. The widely used lithium-ion battery is highly sensitive to the temperature, which affects the performance, lifespan, and safety of the battery. Hence, the proper battery thermal management system (BTMS) is necessary with EVs. BTMS can reduce the negative influence of the temperature by decreasing the maximum battery temperature and temperature difference inside the battery. This article reviews various battery thermal management systems and categorized as active and passive systems. The major focus of the review is on passive BTMS using phase change material (PCM) and heat pipe. The results show that PCM and heat pipe based BTMS can provide better thermal management without any power consumption. Further, the hybrid BTMS with the combination of active/passive is presented, and the research results show that hybrid BTMS can provide better thermal management compared to single BTMS. The BTMS is statistically reviewed in terms of maximum battery temperature and temperature difference, and percentage improvement using BTMS is also provided. This article provides direction towards the development of practical and economic BTMS for with limited power consumption, volume, and weight constraints.
Reconsidering the function of the xyloglucan endotransglucosylase/hydrolase family

Plants possess an outer cell layer called the cell wall. This matrix comprises various molecules, such as polysaccharides and proteins, and serves a wide array of physiologically important functions. This structure is not static but rather flexible in response to the environment. One of the factors responsible for this plasticity is the xyloglucan endotransglucosylase/hydrolase (XTH) family, which cleaves and reconnects xyloglucan molecules. Since xyloglucan molecules have been hypothesised to tether cellulose microfibrils forming the main load-bearing network in the primary cell wall, XTHs have been thought to play a central role in cell wall loosening for plant cell expansion. However, multiple lines of recent evidence have questioned this classic model. Nevertheless, reverse genetic analyses have proven the biological importance of XTHs; therefore, a major challenge at present is to reconsider the role of XTHs in planta. Recent advances in analytical techniques have allowed for gathering rich information on the structure of the primary cell wall. Thus, the integration of accumulated knowledge in current XTH studies may offer a turning point for unveiling the precise functions of XTHs. In the present review, we redefine the biological function of the XTH family based on the recent architectural model of the cell wall. We highlight three key findings regarding this enzyme family: (1) XTHs are not strictly required for cell wall loosening during plant cell expansion but play vital roles in response to specific biotic or abiotic stresses; (2) in addition to their transglycosylase activity, the hydrolase activity of XTHs is involved in physiological benefits; and (3) XTHs can recognise a wide range of polysaccharides other than xyloglucans.
The effects of carbon disulfide driven functionalization on graphene oxide for enhanced Pb(II) adsorption: Investigation of adsorption mechanism

The surface properties of graphene oxide (GO) have been identified as the key effects on the adsorption of Pb(II) from aqueous solutions in this study. This study reveals the effect of the surface reactivity of GO via Carbon Disulfide (CS2) functionalization for Pb(II) adsorption. After successfully preparing CS2 functionalized GO (GOCS), the specific techniques were applied to investigate Pb(II) adsorption onto GOCS. Results indicated that the new sulfur-containing functional groups incorporated onto GOCS significantly enhanced Pb(II) adsorption capacity on GOCS than that of GO, achieving an improvement of 31% in maximum adsorption capacity increasing from 292.8 to 383.4 mg g(-1). The equilibrium adsorption capacity for GOCS was 280.2 mg g(-1) having an improvement of 83.2% over that of 152.97 mg g(-1) for GO at the same initial concentration of 150 mg L-1 under the optimal pH of 5.7. Moreover, the results of adsorption experiments showed an excellent fit to the Langmuir and Pseudo-Second-Order models indicating the monolayer and chemical adsorption, respectively. The mechanism for Pb(II) adsorption on GOCS was proposed as the coordination, electrostatic interactions, cation-pi interactions, and Lewis acidbase interactions. The regeneration study showed that GOCS had an appreciable reusability for Pb(II) adsorption with the adsorption capacity of 208.92 mg g(-1) after five regeneration cycles. In summary, GOCS has been proved to be a novel, useful, and potentially economic adsorbent for the high-efficiency removal of Pb(II) from aqueous solutions. (C) 2020 Elsevier Ltd. All rights reserved.
Nanoparticles for active combination radio mitigating agents of zinc coumarate and zinc caffeinate in a rat model

Zinc coumarate and zinc caffeinate nanoparticles (ZnCoNPs, ZnCaNPs) affect different biological processes. This study aimed to evaluate the mitigating action of ZnCoNPs in combination with ZnCaNPs against liver damage induced by gamma rays (γ-rays). Rats were exposed to 7 Gy of γ-rays and then injected intraperitoneally (i.p) with ZnCoNPs [2U/rat/day (5 mg/kg)] and ZnCaNPs [2U/rat/day (15 mg/kg)] for 7 consecutive days. The results showed that irradiated rats treated with ZnCoNPs (5 mg/kg/body weight) in combination with ZnCaNPs (15 mg/kg/body weight) for 7 days had a significant increases in body weight, antioxidant levels, T helper cell 4 (cluster of differentiation 4 (CD4)), and T cytotoxic cell 8 (cluster of differentiation 8 (CD8)), associated with a marked decrease in lipid peroxidation (LP), nitric oxide(NOx), total free radicals concentrate (TFRC), and DNA fragmentation. There were positive alterations in the morphological state, hematological parameters and the cell cycle phases. Additionally, the histopathological study demonstrated an improvement in the liver tissue of irradiated rats after treatment. Thus, ZnCoNPs and ZnCaNPs could be used as natural mitigating agents to reduce the hazards of ionizing radiation.
Relationships between Renewable Energy Consumption, Social Factors, and Health: A Panel Vector Auto Regression Analysis of a Cluster of 12 EU Countries

One of the key indicators of a population's well-being and the economic development of a country is represented by health, the main proxy for which is life expectancy at birth. Some factors, such as industrialization and modernization, have allowed this to improve considerably. On the other hand, along with high global population growth, the factor which may jeopardize human health the most is environmental degradation, which can be tackled through the transition to renewable energy. The main purpose of our study is to investigate the relationship between renewable energy consumption, social factors, and health, using a Panel Vector Auto Regression (PVAR) technique. We explore the link between some proxy variables for renewable energy consumption, government policy, general public awareness, the market, lobbying activity, the energy dependence on third countries, and health, spanning the period from 1990 to 2015, for a cluster of 12 European countries characterized by common features. Specifically, our analysis shows the importance of having a stringent policy for the development of renewable energy consumption and its influence over other social factors, rather than the existence of causal relationships between health and renewable energy consumption for the analyzed countries. This kind of analysis has a great potential for policy-makers. Further, a deeper understanding of these relationships can create a more e ffective decision-making process.
Potential and economic feasibility of wind energy in south West region of Algeria

The present research is focused on windfarm economic viability and wind power potential assessment by RETScreen and WAsP tools, respectively, for the South-West region of Algeria. This study considers the atlas development of wind characteristics analysis. Hourly mean wind data recorded during the years 2003 to 2008 by ONM "Office National de la Meteorologie" (the Algerian Meteorological Office), is used for the study. The mean wind speed, energy flux, the dominant wind direction, the frequency distribution, and the Weibull distribution scale and shape factors are determined and analyzed. Finally, RETScreen software is used to estimate the energy output and to conduct the economic feasibility of the wind farm in terms of Simple Payback Period (SPP), Internal Rate of Return, Annual Life Cycle Saving, Net Present Value, Year to Positive Cash Flow, Benefit-Cost ratio and cost of electricity production (COE). The economic analysis indicates that the project at Adrar region was economically viable with good energy production of 3146 MWh/yr and a Capacity Factor (CF) of 36%.The SPP was found to be around 3.9 years, and the COE of 3.25 US Cents/kWh was found lower than the wholesale price of electricity during the feed-in tariff period.
New insights into aging-associated characteristics of female subcutaneous adipose tissue through integrative analysis of multi-omics data

Aging could be critical in limiting the application of subcutaneous adipose tissue (SAT) in tissue repair and reconstruction. However, no systematic study on the characteristics of SAT aging has been conducted. In this study, a scanning electronic microscope was used to detect the structural and compositional changes of SAT collected from nine females in three age groups. Multi-omics data of SAT from 37 females were obtained from Gene Expression Omnibus database, and 1860 genes, 56 miRNAs, and 332 methylated genes were identified as being differentially expressed during aging among non-obese females. Using Weighted Correlation Network Analysis (WGCNA), 1754 DEGs were defined as aging-associated genes for non-obese females, distributed among ten co-expression modules. Through Gene Ontology enrichment analysis and Gene Set enrichment analysis on those aging-associated DEGs, SAT aging was observed to be characterized by variations in immune and inflammatory states, mitochondria, lipid and carbohydrate metabolism, and regulation of vascular development. SUPV3L1, OGT, and ARPC1B were identified as conserved and core SAT-aging-related genes, as verified by RT-qPCR among 18 samples in different age groups. Multi-omics regulatory networks of core aging-associated biological processes of SAT were also constructed. Based on WGCNA, we performed differential co-expression analysis to unveil the differences in aging-related co-expression patterns between obese and non-obese females and determined that obesity could be an important accelerating factor in aging processes. Our work provides a landscape of SAT aging, which could be helpful for further research in fields such as repair and reconstruction as well as aging.
Peer-to-peer energy trading potential: An assessment for the residential sector under different technology and tariff availabilities

The increasing number of distributed renewable energy systems and smart-grid technologies, are transforming electricity grids and markets, allowing the growth of peer-to-peer (P2P) energy markets, where consumers and prosumers trade directly with each other. Policymakers are then faced with the task of assessing alternative ways to manage and organize the electricity grid and market. This work explores the potential of P2P energy trading under different available technologies and market paradigms, by analysing the economic benefits for residential consumers and prosumers, given different solar generation contexts and load flexibility levels. The model is applied to the Portuguese residential sector. Results show that with best techno-economic sizing solution for solar photovoltaic (PV), the greater economic gains come from flexibility, reaching a maximum of 28% for consumers and 55% for prosumers, in a P2P trading scenario. However, if we consider flexibility and a high-solar fraction PV sizing, the savings would reach 29% for consumers and 113% for prosumers. P2P economic benefits are found to depend on the type of participating agents involved, demand profile, PV surplus and monetization schemes, level of flexible equipment, which will greatly influence which trading strategies work best, meaning that each case study needs a tailored P2P trading scheme. (C) 2020 Elsevier Ltd. All rights reserved.
Keqinzhangia aquatica gen. et sp. nov. and Pseudocoronospora hainanense gen. et sp. nov., isolated from freshwater in southern China

During an investigation of the diversity of aquatic hyphomycetes from southern China, two interesting isolates were collected. These two isolates were cultured and sequenced, and a BLAST search of their LSU sequences against data in GenBank revealed that the closest related taxa were in the genus Microthyrium. Phylogenetic analyses, based on the combined sequence data from the internal transcribed spacer (ITS) and large nuclear subunit ribosomal DNA (LSU), revealed that our isolates belong to the Microthyriaceae. Combined morphological characters allowed us to describe our isolates as two new genera and species in Microthyriaceae, named as: Keqinzhangia aquatica and Pseudocoronospora hainanense. The full descriptions, illustrations, and a phylogenetic tree showing the position of the two new genera were provided in this paper.