ahmedabdelwahed/Medical_papers_title_and_abstract_NLP_dataset huggingface dataset:
COVID-19 Pandemic-Related Arguments in Polish Civil Litigation

The aim of this paper is to analyse the legal record on civil litigation from mid-March 2020 to mid-July 2021 and examine COVID-19 pandemic-related arguments in a sample of litigated cases heard in Polish courts, more precisely 41 cases. In an attempt to establish the number and types of court cases in which such arguments have been raised, the population of individual case records was accessed electronically from the Ordinary Courts Judgments Portal (Pol. Portal Orzeczeń Sądów Powszechnych). The analysed research material consists of texts of written justifications published along with rulings of courts of the first instance in the Portal, except for texts regarding criminal cases and widely understood labour cases. This paper refers to certain theoretical aspects of argument and argumentation. Then, it sheds light on the use of COVID-19 pandemic-related arguments by the parties involved in litigation-as reported by the courts in written justifications-considering, amongst others, whether those arguments were found convincing by the courts. Based on a survey of relevant cases, an attempt was made to identify categories of COVID-19 pandemic-related arguments of the parties involved in litigation, raised in their legal submissions. Also a look into the tendencies in this regard was taken to see whether any patterns emerge and it is possible (or not) to discern different trends in the analysed phenomena. The point of the analysis in this article is both descriptive and normative.
Alkali metals association in biomass and their impact on ash melting behaviour

Selected agricultural and energy crop biomass ashes represented by two mixed cereal straws, corn straw, Miscanthus x Gigantus and Salix Viminalis were chosen for ash behaviour investigation and prediction of operating problems during biomass combustion. The presence of aggressive species in the ash generate operational problems of heat exchanging surfaces in power boilers connected with slagging and fouling processes, limiting the use of biomass direct combustion for energy production. In this work, thermal behaviour characteristics, transformation properties of the inorganic components and ash fusion temperatures of biomass ashes were investigated using thermal analysis (STA), X-ray diffraction (XRD) and high-temperature microscope. The special attention was focused on the evaluation of potassium compounds presented in ashes. Potassium was detected as KCl, K2SO4, K2CO3 and K3PO4. It was noted, that presence and concentration of alkali metals, silicon and calcium compounds has the major impact on fusion temperatures of studied ashes. Leaching process of ash elements using water, ammonium acetate and hydrochloric acid solutions was performed to determine the association of alkali metals in the raw material. Based on the results, a mineral matter composition recalculation model was proposed to predict alkali compounds concentration in the fuel. The model might be also used to determine the risk of eutectics formation, which have the strongest influence on ash melting behaviour.
Coupling coordination analysis of urbanization and eco-environment in Yanqi Basin based on multi-source remote sensing data

While multi-source remote sensing technology has the advantage of accurate and objective quantification, an understanding of the coupling and coordination between regional urbanization and ecological environment is the basis for achieving regional sustainable development. This paper builds the Remote Sensing Ecological Index (RSEI) based on Landsat data and Tiangong-2 WIS, using multi-source remote sensing data to comprehensively evaluate the coupling and coordination relationship between urbanization and ecological environment with a coupling coordination degree model in China's typical arid area of Yanqin Basin during 2000-2018. The results show the RSEI index has a certain rationality and superiority in assessing the ecological environment. In 2000-2018, the ecological environment of the Yanqi Basin was optimized, the RSEI index increased by 23.06%, and the overall ecological environment was at a good level (0.6-0.8). At the same time, the urbanization level of each town had been significantly improved in Yanqi Basin. Through the urban center of gravity transfer model, it was found that direction of urban development shifted to the southwest direction by 7.49 km, which is basically consistent with the position of poor ecological environment. Finally the current urbanization and ecological environment coupling relationship in urban areas of Yanqi Basin was found to exhibit a sluggish rate of urbanization with a moderate imbalance between urbanization with ecological environment. Therefore, when making decisions for planning the regional economic development, the concept of ecological relationships should be integrated to effectively protect and achieve a healthy and sustainable development of the region.
Hsa_circ_0003288 facilitates tumor progression by targeting miR-145 in non-small cell lung cancer cells

Circular RNA (circRNA) has been shown to participate in various tumors, including lung cancer. In the present study, we explored the expression and functional relevance of hsa_circ_0003288 in human non-small cell lung cancer (NSCLC). We verified that hsa_circ_0003288 expression was upregulated in lung cancer tissues and cell lines. Overexpression of hsa_circ_0003288 dramatically promoted lung cancer cell proliferation, colony formation, inhibited apoptosis, and increased cell migration and invasion in vitro. Xenograft experiments showed that hsa_circ_0003288 overexpression accelerated tumor growth in vivo. Mechanistically, hsa_circ_0003288 negatively regulated miR-145 to exert the oncogenic role in lung cancer. Overexpression of miR-145 decreased cell proliferation, induced apoptosis, and suppressed migration and invasion in lung cancer. Additionally, miR-145 co-transfection abolished the oncogenic role of hsa_circ_0003288. Collectively, these findings identified a novel regulatory role of hsa_circ_0003288/miR-145 axis in the progression of NSCLC.
Blockade of α2-Adrenergic Receptors Inhibits Functional Parameters of Langendorff-Isolated Rat Heart

We studied the effect of α2-adrenoreceptor antagonist yohimbine in concentrations of 10-9-10-6 M on the inotropy, chronotropy, and coronary flow of the Langendorff-isolated rat heart. It was found that antagonist of α2-adrenoreceptors yohimbine changes all the studied parameters of the isolated heart. The force of left ventricular myocardial contraction, HR, and coronary flow decreased after application of all concentrations of α2-adrenoreceptor antagonist. The maximum inotropic, chronotropic, and vascular effects were observed when the antagonist was applied to the perfused solution in a concentration of 10-9 M. The minimum decrease in coronary flow and HR was observed when yohimbine was applied in a concentration of 10-8 M; minimum effect on myocardial contractility was revealed at α2-adrenoreceptor blocker concentration of 10-7 M.
Evidence-based strategies to reduce the incidence of postoperative delirium: a narrative review

Delirium is one of the most commonly occurring postoperative complications in older adults. It occurs due to the vulnerability of cerebral functioning to pathophysiological stressors. Identification of those at increased risk of developing delirium early in the surgical pathway provides an opportunity for modification of predisposing and precipitating risk factors and effective shared decision-making. No single delirium prediction tool is used widely in surgical settings. Multi-component interventions to prevent delirium involve structured risk factor modification supported by geriatrician input; these are clinically efficacious and cost effective. Barriers to the widespread implementation of such complex interventions exist, resulting in an 'implementation gap'. There is a lack of evidence for pharmacological prophylaxis for the prevention of delirium. Current evidence suggests that avoidance of peri-operative benzodiazepines, careful titration of anaesthetic depth guided by processed electroencephalogram monitoring and treatment of pain are the most effective strategies to minimise the risk of delirium. Addressing postoperative delirium requires a collaborative, whole pathway approach, beginning with the early identification of those patients who are at risk. The research agenda should continue to examine the potential for pharmacological prophylaxis to prevent delirium while also addressing how successful models of delirium prevention can be translated from one setting to another, underpinned by implementation science methodology.
Testicular torsions in veterinary medicine

The purpose of this review is to provide a comprehensive comparison of spermatic cord torsion in domestic animals. Spermatic cord torsion leads to occlusion of testicular blood flow resulting in ischemia and tissue hypoxia. Spermatic cord torsion has been reported in all domestic mammals but dogs and horses are overrepresented. Abdominal pain (colic), anorexia, vomiting, lameness, and stiff gait are the most common clinical signs reported. The condition may be asymptomatic in cases of a low degree of spermatic cord torsion. In dogs, spermatic cord torsion is most commonly reported in undescended testes, which in some cases are neoplastic. However, in horses, spermatic cord torsion occurs more commonly in scrotal testes. Surgical treatment for spermatic cord torsion depends upon the degree and duration of torsion. If the affected testis is located within the scrotum and determined to still be viable, detorsion with orchidopexy can be performed. Orchiopexy of the unaffected scrotal testis is also recommended in stallions. If the affected testis cannot be salvaged, unilateral or bilateral orchidectomy is recommended. In all cases of spermatic cord torsion of an undescended testis, orchidectomy is recommended. Veterinarians should be aware of the clinical signs and treatment options for spermatic cord torsion in domestic mammals.
Immunological effect of Moringa Oleifera leaf extract on vaccinated and non-vaccinated Hubbard chickens experimentally infected with Newcastle virus

In veterinary medicine plant based medicine is achieving a huge importance worldwide. This research was subjected to rectify the hydrophilic Moringa Oleifera alcoholic leaves extract could improve the immune system in vaccinated and non-vaccinated broiler Hubbard chickens experimentally exposed to Newcastle disease (ND) virus. Seventy five chicks with age one day old were splitted randomly into five groups equally in distribution with fifteen chick in each group. Group I was untreated unvaccinated (control negative group) while group IV was infected group with NDV (control positive group). The experimental Groups II and V were given daily oral treatment of hydrophilic alcoholic leaves extract of M. oleifera at 200 mg/kg body weight until day 21 of age while groups III and V were ND vaccinated with La Sota strain of ND vaccines. The four groups (II, III, IV, V) were infected with ND virus velogenic strain (VNDV) on day 21. Following to infection, Monitoring of birds were done daily for clinical signs, postmortem examination, morbidity and mortality. Cellular, humeral immune response and phagocytic activity were evaluated and the data were statistically analyzed using (SPSS). Total and differential cell numbers as well as Haemagglutination inhibition (HI) titre increased in the extract treated and vaccinated group which give total protection against NDV much more than treated and unvaccinated group. As a result it could be recommended to use M. Olifera extract from the first day of rearing in Hubbard chicken with ND vaccination program as a prophylactic treatment in protection of birds against ND infection.
Diagnosis and management of acute coronary syndromes

Acute coronary syndromes are a significant cause of morbidity and mortality in Australia. Outcomes are likely to be improved by rapid and accurate diagnosis, and early intervention The development of high-sensitivity troponin assays has revealed previously unrecognised types of myocardial injury, for which conventional management guidelines for myocardial infarction may not confer similar benefits. The distinction between myocardial injury and myocardial infarction has therefore become increasingly important Once the diagnosis of acute myocardial infarction has been made, individualised acute reperfusion strategies including percutaneous coronary intervention or fibrinolytic therapy should be considered. Secondary prevention strategies should be implemented before hospital discharge.
Assessment of sustainability indicators for green building manufacturing using fuzzy multi-criteria decision making approach

Over the past decades, building manufacturing has caused serious environmental impacts, despite its role in the national economic growth. Thus, in developing strategic plans for economic growth, many governments consider the application of green manufacturing building and technologies as key factors towards a greener economy and lower carbon emission. However, so far, there have been limited efforts relating to the application of eco-efficiency ideas in building manufacturing. In fact, environmental sustainability in building project and delivery is still at a nascent stage. Thus, this study aims to identify and rank the sustainability indicators for assessing green building manufacturing in Malaysia by considering Green Building Index (GBI), which is the most applied sustainability rating tool in the country. Data is collected from a panel of experts and fuzzy Decision-Making Trial and Evaluation Laboratory (DEMATEL) is performed to reveal the importance level and relationships among sustainability indicators in green building manufacturing. Results show that "Energy Efficiency" and "Indoor Environmental Quality" are the most important, while "Water Efficiency" and "Innovation" are the least important criteria in assessing green building manufacturing in Malaysia. This study can serve as a guideline to select and promote the optimum practices in green building manufacturing. (C) 2020 Elsevier Ltd. All rights reserved.
A comparison of steam and oxygen fed biomass gasification through a techno-economic-environmental study

Economically, fossil fuels remain the main source of energy despite their high emissions of greenhouse gases. However, biomass, a renewable fuel with CO2 neutrality, has experienced widespread attention as a potential contributor to sustainable development of the energy sector. Gasification is an important thermochemical process that converts biomass feedstock into H-2-rich combustible gases, which are favoured by wide downstream applications. The use of pure steam or oxygen as a gasifying agent is preferred to increase the yield of combustible gases. Consequently, hydrogen is utilised as an important intermediary in the generation of value-added products such as urea, fuels and power. This study compares the biomass gasification using oxygen-only and steam-only gasifying agents. Moreover, the study examines a poly-generation system that consumes biomass feedstock of multiple sources to produce high grade Fisher-Tropsch liquids, methanol, urea, and power. To achieve this aim, four Aspen Plus simulation flowsheets are developed considering both gasifiying agents and compared utilising the built-in economic and environmental capabilities. The results obtained from the economic and environmental evaluation demonstrate the excellence of steam-only biomass gasification in providing profitable and cleaner products. The methanol production using steam gasification is the most economical solution with a net profit per input of $0.12 per kg of biomass input and the lowest emissions pathway with 0.68 kg of CO2-e per biomass input. The relative nature of the results can offer diverse perspectives depending on the market situation of the products. Consequently, analysing the results relative to production capacity, power generation using steam gasification achieves a net profit approximated at $0.80 per kg of product, whilst methanol production using steam gasification remains the lowest environmental impact solution with 2.32 kg of CO2-e per output product.
Association of dietary patterns with obesity and metabolically healthy obesity phenotype in Chinese population: a cross-sectional analysis of China Multi-Ethnic Cohort Study

Metabolically healthy obesity (MHO) might be an alternative valuable target in obesity treatment. We aimed to assess whether alternative Mediterranean (aMED) diet and Dietary Approaches to Stop Hypertension (DASH) diet were favourably associated with obesity and MHO phenotype in a Chinese multi-ethnic population. We conducted this cross-sectional analysis using the baseline data of the China Multi-Ethnic Cohort study that enrolled 99 556 participants from seven diverse ethnic groups. Participants with self-reported cardiometabolic diseases were excluded to eliminate possible reverse causality. Marginal structural logistic models were used to estimate the associations, with confounders determined by directed acyclic graph (DAG). Among 65 699 included participants, 11·2 % were with obesity. MHO phenotype was present in 5·7 % of total population and 52·7 % of population with obesity. Compared with the lowest quintile, the highest quintile of DASH diet score had 23 % decreased odds of obesity (OR = 0·77, 95 % CI 0·71, 0·83, Ptrend < 0·001) and 27 % increased odds of MHO (OR = 1·27, 95 % CI 1·10, 1·48, Ptrend = 0·001) in population with obesity. However, aMED diet showed no obvious favourable associations. Further adjusting for BMI did not change the associations between diet scores and MHO. Results were robust to various sensitivity analyses. In conclusion, DASH diet rather than aMED diet is associated with reduced risk of obesity and presents BMI-independent metabolic benefits in this large population-based study. Recommendation for adhering to DASH diet may benefit the prevention of obesity and related metabolic disorders in Chinese population.
Comprehensive evaluation of national electric power development based on cloud model and entropy method and TOPSIS: A case study in 11 countries

Electric power is the foundation of the development of national economy, it is necessary to make a comprehensive evaluation of its development. Firstly, 17 secondary electric power development evaluation indexes are established from four aspects: electricity supply, electricity consumption, electrification level and carbon emission. Secondly, based on the cloud model, the subjective evaluation and analysis of the primary evaluation index for the national electric power development are realized. Then, the entropy method is used to objectively evaluate and analyze the secondary evaluation index of national electric power development. And the objective evaluation value of the primary evaluation index for the national electric power development is obtained. Thirdly, the TOPSIS method is used to integrate the subjective evaluation value obtained by the cloud model and the objective evaluation value obtained by the entropy method to comprehensively evaluate the status of national electricity development. Next, by collecting the electric power development evaluation index data of 11 typical countries, the electric power development of 11 countries was evaluated and analyzed by using the CM-EM-TOPSIS method proposed in this paper. From the results of the comprehensive evaluation of China's electric power development, it is found that compared with other countries, the sensitivity of the queueing indicator value to the subjective evaluation weight is lower in China. Finally, according to the results of comprehensive evaluation and analysis of electric power development, the managerial implication is explored in China. (C) 2020 Elsevier Ltd. All rights reserved.
Differential Effect of Non-Purified and Semi-Purified Standard Diets on Kynurenine and Peripheral Metabolites in Male C57BL/6J Mice

The kynurenine (Kyn) pathway plays crucial roles in several inflammation-induced disorders such as depression. In this study, we measured Kyn and other related molecules in the blood plasma, brain, and urine of male C57BL/6J mice (B6) fed non-purified (MF) and semi-purified (AIN-93G and AIN-93M) standard rodent diets. Mice fed MF had increased plasma Kyn levels compared with those on AIN93-based diets, as well as decreased hippocampal Kyn levels compared with those fed AIN-93G. Previous studies showed that branched chain amino acids (BCAAs) suppress peripheral blood Kyn transportation to the brain, but plasma BCAA levels were not significantly different between the diet groups in our study. Urine metabolome analysis revealed that feed ingredients affected the excretion of many metabolites, and MF-fed mice had elevated excretion of kynurenic and quinolinic acids, pivotal metabolites in the Kyn pathway. Collectively, the level of critical metabolites in the Kyn pathway in the central and peripheral tissues was strongly affected by feed ingredients. Therefore, feed selection is a critical factor to ensure the reproducibility of experimental data in studies involving rodent models.
Formulation and development of novel control release transdermal patches of carvedilol to improve bioavailability for the treatment of heart failure

The main aim of this study is to optimize and evaluate transdermal patch of Carvedilol by the use of different polymer and different permeation enhancers which help to release drug in controlled action and thereby increase the bioavailability of the drug. Main objective was to avoid first pass metabolism of Carvedilol. Transdermal patches were developed by solvent evaporation method. The combination of Eudragit RS-100 as rate controlling polymer and Span 80 as a permeation enhancer was found to be ideal formulation (Formulation F7) with maximum drug release i.e. 100.29 ± 0.44 % within 12 h. Formulation F7 showed maximum bioavailability and showed maximum drop of BP at 6 h. From this study the conclusion was, transdermal patch of Carvedilol which contains Eudragit RS-100 polymer and Span 80 as penetration enhancer produced sustained and continued drug release.