ahmedabdelwahed/Medical_papers_title_and_abstract_NLP_dataset huggingface dataset:
Exploring the linkage among energy intensity, carbon emission and urbanization in Pakistan: fresh evidence from ecological modernization and environment transition theories

This study uses ecological modernization and environmental transition theories to estimate the interaction among energy intensity, carbon emission and urbanization for the period of 1980-2017. We have systematically examined the empirical connections among emission, urbanization, income per capita, imports, exports, energy use, trade openness and energy intensity. The Johnson co-integration and Vector Error Correction Model (VECM) causality methods are employed for the sake of analysis. Overall findings confirm the dynamic and U-shaped relationship between emission and urbanization, and carbon emission and income per capita. The empirical results of urbanization, inflation and financial development illustrate positive association with the energy intensity, whereas trade openness, labour force participation and carbon emission show a negative association with the dependent variable. Moreover, outcomes of causality analysis provide evidence of varied causality link among the variables across the models. The study provides the implications for the decision makers in Pakistan to choose new urbanization patterns that are less reliant on energy consumption.
Role of renewable energy and globalization on ecological footprint in the USA: implications for environmental sustainability

The role of renewable energy and globalization on ecological footprint is investigated in the USA by controlling for the effects of financial development and real output using quarterly data from 1985:Q1 to 2014:Q4. We apply the minimum Lagrange multiplier unit root test, multiple structural break cointegration test, and autoregressive distributed lag (ARDL) estimation approach. The empirical evidence suggests that, in the long run, renewable energy and real output exert negative pressure on ecological footprint while financial development and globalization exert positive pressure on ecological footprint. The short-run results indicate that renewable energy, financial development, real output, and globalization are positively linked to ecological footprint. The vector error correction model Granger causality results, in the long run, divulge that ecological footprint, consumption of renewable energy, real output, and globalization Granger-cause financial development while ecological footprint, renewable energy, financial development, and globalization Granger-cause real output. The results also show that, in the short run, renewable energy and globalization cause ecological footprint and real output causes renewable energy, while renewable energy causes globalization. The finding also reveals that the causality between real output and globalization, as well as globalization and financial development, is bidirectional. Therefore, our findings provide insights for policymakers to consider consumption of renewable energy as a surest way to mitigate carbon dioxide emissions.
Inconvenience and adaptation in Japanese adult achondroplasia and hypochondroplasia: A cross-sectional study

The health-related quality of life is reduced in patients with achondroplasia (ACH) and hypochondroplasia (HCH); however, the detailed inconveniences in the daily living and individual adaptations have not been elucidated. This study aimed to evaluate the inconvenience and adaptation in patients with ACH/HCH. A cross-sectional study was conducted in patients with ACH/HCH aged 20 yr or older. Questionnaires were sent to 567 patients (described 86) with a medical history at the co-authors' institutions or who were registered at the patients' association with ACH in Japan. The questionnaire included a free description format for the inconveniences and adaptations in daily living; a content analysis was performed. The recorded inconveniences included 148 physical, 84 mental, and 52 social problems. Patients who underwent spine surgery had significantly more recorded physical problems than those who did not (p < 0.05). Pain and numbness were significantly higher in patients aged ≥ 50 yr (p < 0.05). The 160 and 1 adaptations were for physical and social problems, respectively. No patient adaptation was found for mental health problems. Individual adaptations by ACH/HCH patients can improve only some aspects of physical and social problems. Multilateral social support is needed to resolve patients' issues.
The Impact of Energy Consumption and Economic Growth on Carbon Dioxide Emissions

This study explored the effect of energy consumption and economic growth on CO2 emissions. The relationship between energy consumption, economic growth and CO2 emissions was assessed using regression analysis (the pooled OLS regression and fixed effects methods), Granger causality and panel cointegration tests. Data from 70 countries between 1994-2013 were analysed. The result of the Granger causality tests revealed that the study variables (population, capital stock and economic growth) have a bi-directional causal relationship with CO2 emissions, while energy consumption has a uni-directional relationship. Likewise, the outcome of the cointegration tests established that a long-run relationship exists among the study variables (energy consumption and economic growth) with CO2 emissions. However, the pooled OLS and fixed methods both showed that energy consumption and economic growth have a significant positive impact on CO2 emissions. Hence, this study supports the need for a global transition to a low carbon economy primarily through climate finance, which refers to local, national, or transnational financing, that may be drawn from public, private and alternative sources of financing. This will help foster large-scale investments in clean energy, that are required to significantly reduce CO2 emissions.
Circular ecosystem innovation: An initial set of principles

A circular economy maximizes the value of material resources and minimizes greenhouse gas emissions, resource use, waste and pollution. We will posit that circularity needs to be understood as a property of a system (e.g., the mobility system of a city), rather than a property of an individual product or service (e.g., a car or a car-sharing service). Hence, there is a need for more knowledge on how to innovate towards 'circular ecosystems'. This study proposes a set of principles for 'circular ecosystem innovation', based on: 1) a concise literature review to retrieve recommended principles on how to successfully innovate in ecosystems, 2) a mobility case of circular ecosystem innovation to investigate how relevant and useful these principles are for circular oriented innovation. The case data include 20 interviews, workshop data and internal background documents. The identified principles can be categorized in three groups: 1) collaboration (i.e., how firms can interact with other organizations in their ecosystem to innovate towards circularity), 2) experimentation (i.e., how firms can organize a structured trial-and-error process to implement greater circularity) and 3) platformization (i.e., how firms can organize social and economic interactions via online platforms to achieve greater circularity). Future research may focus on identifying opportunities and barriers to applying these principles in different contexts than in the one that is investigated in the present study. (C) 2020 Elsevier Ltd. All rights reserved.
An integrated GIS approach for site selection of floating offshore wind farms in the Atlantic continental European coastline

This study presents a novel method for the selection of sites for floating wind farms based on marine spatial optimization. After providing a review of the present state of the art, a tool based on geographic information systems is presented, consisting of three main stages and built in Python language. The first stage collects and analyses the information of the different regulatory bodies, marine spatial planning, maritime concessions and other sources. The second stage excludes not feasible sites for floating wind farms, based mostly on marine space use and on environmental constraints. The third stage characterises the available locations based on five major categories that are spatially dependent: metocean data, viability data, logistics, facilities, marine environment and techno-economic data. The proposed methodology is implemented at the Europe Atlantic coast, with specific reference to Portugal, Spain and France. These three countries together combine 3.362.408 km(2) of the Atlantic Exclusive Economic Zone, where in only 0.22% of that area could host floating offshore wind turbines. While further detailed studies about locations and legislative considerations are required, the effort made has contributed to eliminate unsuitable areas and identify those where sustainability can be maximized.
The Relationship Between Drinking Behavior and Conversational Processes During a Brief Alcohol Reduction Intervention for People with HIV

People with HIV (PWH) frequently engage in unhealthy alcohol use, which can adversely affect antiretroviral adherence and HIV disease progression. Brief interventions based on Motivational Interviewing (MI), including the Brief Negotiated Interview (BNI), can help to reduce drinking. This study examines MI processes observed during a single 15-20 min BNI session delivered by social workers to PWH with unhealthy alcohol use (N = 59) in the context of a stepped care intervention to reduce alcohol consumption. BNI sessions were coded for technical and relational processes encouraged in MI, such as autonomy support, instructive language, and self-exploration. Multiple regression analyses explored the relationship between: (1) Participants' pre-intervention drinking behaviors (weekly drinks and heavy drinking days) and these MI processes, and (2) MI processes and intervention outcomes. Results indicated that PWH who reported more weekly drinks at baseline engaged in less self-exploration, while social workers delivering the BNI used less instructive language for those who reported more heavy drinking days. PWH who engaged in more self-exploration and received more autonomy support had fewer heavy drinking days 6 months after the intervention. These findings suggest the value of providing more opportunities within BNIs to encourage self-exploration, as it may help to enhance intervention efficacy.
Peri-operative neurological monitoring with electroencephalography and cerebral oximetry: a narrative review

Surgery and anaesthesia subject the brain to considerable stress in the peri-operative period. This may be caused by potentially neurotoxic anaesthetic drugs, impaired cerebral perfusion and reperfusion injury related to surgery or thromboembolic events. Patient monitoring using electroencephalogram and cerebral oximetry can assist in optimising depth of anaesthesia and assessment of cerebral metabolic activity. However, research findings have been contradictory as to whether these monitors can help ameliorate peri-operative neurocognitive complications. In this narrative review, we will discuss recent evidence in the use of electroencephalography and cerebral oximetry and the underlying scientific principles. It is important to appreciate the raw electroencephalographic changes under anaesthesia and those associated with ageing, in order to interpret depth of anaesthesia indices correctly. Cerebral oximetry is useful not only for the detection of cerebral desaturation but also to identify those patients who are particularly vulnerable to injury, for better risk stratification. An algorithm-based approach may be most effective in managing the episodes of cerebral desaturation.
Psychiatric-Like Impairments in Mouse Models of Spinocerebellar Ataxias

Many patients with spinocerebellar ataxia (SCA) suffer from diverse neuropsychiatric issues, including memory impairments, apathy, depression, or anxiety. These neuropsychiatric aspects contribute per se to the reduced quality of life and worse prognosis. However, the extent to which SCA-related neuropathology directly contributes to these issues remains largely unclear. Behavioral profiling of various SCA mouse models can bring new insight into this question. This paper aims to synthesize recent findings from behavioral studies of SCA patients and mouse models. The role of SCA neuropathology for shaping psychiatric-like impairments may be exemplified in mouse models of SCA1. These mice evince robust cognitive impairments which are shaped by both the cerebellar as well as out-of-cerebellar pathology. Although emotional-related alternations are also present, they seem to be less robust and more affected by the specific distribution and character of the neuropathology. For example, cerebellar-specific pathology seems to provoke behavioral disinhibition, leading to seemingly decreased anxiety, whereas complex SCA1 neuropathology induces anxiety-like phenotype. In SCA1 mice with complex neuropathology, some of the psychiatric-like impairments are present even before marked cerebellar degeneration and ataxia and correlate with hippocampal atrophy. Similarly, complete or partial deletion of the implicated gene (Atxn1) leads to cognitive dysfunction and anxiety-like behavior, respectively, without apparent ataxia and cerebellar degeneration. Altogether, these findings collectively suggest that the neuropsychiatric issues have a biological basis partially independent of the cerebellum. As some neuropsychiatric issues may stem from weakening the function of the implicated gene, therapeutic reduction of its expression by molecular approaches may not necessarily mitigate the neuropsychiatric issues.
Behavioral and technical perspectives of green supply chain management practices: Empirical evidence from an emerging market

Recently, companies in emerging markets have implemented green supply chain management (GSCM) practices to tackle environmental issues. Drawing upon socio-technical systems theory, this study develops a conceptual model suggesting a sequential effect between two distinct categories of GSCM practices, namely behavioral (human and soft aspects) and technical (tangible and hard aspects) practices, on performance. We employ structural equation modeling method to test hypotheses based on survey responses from 200 Chinese manufacturers. The categorization of behavioral and technical GSCM practices and research findings contribute to the GSCM literature. Statistical results demonstrate the complete mediation effect of technical GSCM practices (e.g., green design, green manufacturing and reverse logistics) on the relationship between behavioral GSCM practices (e.g., relationship with customers and suppliers) and organizational performance. Such results recommend that companies in emerging markets should highlight behavioral GSCM practices first and then implement necessary technical GSCM practices to reap economic, environmental and operational performance.
Individual differences and the relationship between education and religiosity in longitudinal versus cross-sectional studies

We show that the relationship between education and religiosity is positive in cross-sectional analyses and negative in longitudinal analyses. We explain this discrepancy by suggesting that the former relationship is due to the positive association of both education and religiosity with dispositional conformity, while the latter represents a causal effect of education on apostasy.
An evaluation of the phytochemical composition, antioxidant and cytotoxicity of the leaves of Litsea elliptica Blume - An ethnomedicinal plant from Brunei Darussalam

Litsea elliptica is traditionally believed to prevent and treat stomach ulcers, cancer, fever and headaches. This study investigates the phytochemical composition, antioxidant and cytotoxic effects of L. elliptica leaf extracts. The phytochemical content was determined via GCMS analysis and total phenolic content (TPC) and total flavonoid content (TFC) were analysed using the Folin-Ciocalteu and aluminium-chloride assays. Antioxidant activities were determined using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenging, 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) scavenging and ferric-ion reducing antioxidant power (FRAP) assays, whereas cytotoxicity was determined using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) and calcein/ethidium viability assays. The mechanism of cytotoxicity was investigated using Annexin V/propidium iodide. Modifications in the mitochondria were investigated using MitoTracker Red CMXRos. Ten and twenty-six compounds were characterized in the young-leaf and mixed-leaves extracts, respectively. The young-leaf methanolic extract demonstrated the highest antioxidant capacity of at least four-folds greater than the mixed-leaves and ethanolic extracts. The methanolic extract also had higher TPC and TFC values compared to the ethanolic extract. Although the mixed L. elliptica leaves had lower antioxidant capacities compared to the young leaves, the mixed leaves extract has demonstrated greater cytotoxicity against the A549 cancer cell line. Further investigation revealed that the L. elliptica leaves-induced cytotoxicity on A549 cells was possibly via the non-inflammatory mitochondria-mediated apoptotic pathway. Overall, our results showed the potential of the L. elliptica leaves possessing cytotoxic activities against carcinoma cells where the compounds present can be further investigated for its therapeutic application.
Hematological and biochemical investigations on the effect of curcumin and Thymoquinone in male mice exposed to Thioacetamide

Currently, living organisms are increasingly exposed to many toxic chemicals in the environment. These substances pose a threat to human life, other living organisms and ecosystem. In fact, there is an increasing requirement to search for safe therapeutic sources today. Medicinal plants and natural products have become of great importance globally because of their therapeutic potential and medicinal properties, as well as their availability and the absence of harmful side effects for most of them. The present study was designed to explore the potential protective effect of curcumin (CUR) and thymoquinone (TQ) in male rats exposed to thioacetamide (TAA). The experimental mice were divided into eight groups. Group 1 was served as control. Group 2 was exposed to 50 mg/ kg body weight of TAA. Group 3 was exposed to CUR and TAA. Mice of group 4 were treated with TQ and TAA. Mice of group 5 were exposed to CUR plus TQ and TAA. Group 6 was supplemented with CUR. Group 7 was subjected to TQ. Mice of group 8 were treated with CUR and TQ. Hematological and biochemical alterations were evaluated after one month. Significant increases of white blood corpuscles (WBC), alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), total bilirubin (TB), tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) values were observed in group 2, while the values of red blood corpuscles (RBC), hemoglobin (Hb(, hematocrit (Hct), glutathione (GSH) and superoxide dismutase (SOD) were statistically decreased. Treatment with CUR, TQ and their combination inhibited the hematological and biochemical alterations induced by TAA toxicity. Moreover, the most protective effect was observed in mice treated with CUR plus TQ. These new results suggested that the protective effect of CUR and TQ attributed to their antioxidant properties.
Spatiotemporal Patterns of COVID-19 Impact on Human Activities and Environment in Mainland China Using Nighttime Light and Air Quality Data

The sudden outbreak of the COVID-19 pandemic has brought drastic changes to people's daily lives, work, and the surrounding environment. Investigations into these changes are very important for decision makers to implement policies on economic loss assessments and stimulation packages, city reopening, resilience of the environment, and arrangement of medical resources. In order to analyze the impact of COVID-19 on people's lives, activities, and the natural environment, this paper investigates the spatial and temporal characteristics of Nighttime Light (NTL) radiance and Air Quality Index (AQI) before and during the pandemic in mainland China. The monthly mean NTL radiance, and daily and monthly mean AQI are calculated over mainland China and compared before and during the pandemic. Our results show that the monthly average NTL brightness is much lower during the quarantine period than before. This study categorizes NTL into three classes: residential area, transportation, and public facilities and commercial centers, with NTL radiance ranges of 5-20, 20-40 and greater than 40 (nW center dot cm(-2)center dot sr(-1)), respectively. We found that the Number of Pixels (NOP) with NTL detection increased in the residential area and decreased in the commercial centers for most of the provinces after the shutdown, while transportation and public facilities generally stayed the same. More specifically, we examined these factors in Wuhan, where the first confirmed cases were reported, and where the earliest quarantine measures were taken. Observations and analysis of pixels associated with commercial centers were observed to have lower NTL radiance values, indicating a dimming behavior, while residential area pixels recorded increased levels of brightness after the beginning of the lockdown. The study also discovered a significant decreasing trend in the daily average AQI for mainland China from January to March 2020, with cleaner air in most provinces during February and March, compared to January 2020. In conclusion, the outbreak and spread of COVID-19 has had a crucial impact on people's daily lives and activity ranges through the increased implementation of lockdown and quarantine policies. On the other hand, the air quality of mainland China has improved with the reduction in non-essential industries and motor vehicle usage. This evidence demonstrates that the Chinese government has executed very stringent quarantine policies to deal with the pandemic. The decisive response to control the spread of COVID-19 provides a reference for other parts of the world.
The role of renewable energy, alternative and nuclear energy in mitigating carbon emissions in the CPTPP countries

The paper investigates the role of renewable energy and alternative and nuclear energy in mitigating CO2 emissions. Trade openness is added to consider its effect on the environment, as it appears to be a crucial factor in interregional cooperation and development. We adopt a sample of nine signatories to the Comprehensive and Progressive Agreement for Trans-Pacific Partnership (CPTPP) from 1971 to 2014. Various time-series econometric methods are utilized including two long-run estimators - fully modified ordinary least squares (FMOLS) and dynamic ordinary least squares (DOLS) - and a Granger-causality test. Several noteworthy findings are achieved from this paper. First, the inverse U-shaped relationship is found in six countries: Australia, Canada, Chile, New Zealand, Peru and Vietnam. The U-shaped relationship is found in Japan and Malaysia whereas no evidence is observed in Mexico. Second, the adoption of either renewable energy or alternative and nuclear energy would mitigate CO2 emissions and trade openness plays an important role in facilitating this effect. Third, the directions of Granger causality among the variables of interests including consumption of renewable energy; consumption of alternative and nuclear energy, trade openness and CO2 emissions, do vary across countries and between the short term and the long term. (C) 2020 Published by Elsevier Ltd.