ahmedabdelwahed/Medical_papers_title_and_abstract_NLP_dataset huggingface dataset:
Insect Farming for Feed and Food Production from a Circular Business Model Perspective

The studies focused on the use of insects have outlined numerous reasons for using insects as food and feed as an important method to increase food opportunities for consumers. Insects have been emphasized as a food source with a low environmental impact due to the limited requirement for arable land and water, low ecological cost, and high-quality protein provision. In Europe and Western countries, insect farming is a growing business in which, however, some critical economic aspects must be recognized. The sector needs to be adequately promoted to rationally exploit the huge amount of potential. As such, the aim of this study was to analyze the recent research on economic aspects related to insect farming for feed and food production with the purpose of providing evidence of the critical economic points in this emerging sector. The focus was mainly oriented to understanding how insect farming can foster virtuous circular economic processes, specifically considering economic aspects on the basis of the limited literature currently available and the circular economic principles. A circular business model approach was proposed to address the entire insect-based feed and food supply chain from a circular economic perspective. In our opinion, the findings underline some economic research questions that need to be addressed in the near future, and the conceptual approach can be individualized to help increase cost- and eco-effectiveness from a circular economic perspective.
What are the critical barriers to the development of hydrogen refueling stations in China? A modified fuzzy DEMATEL approach

Hydrogen fuel cell vehicle is one of the important modalities of the next generation of new energy vehicles. As the basic infrastructure of hydrogen fuel cell vehicles, hydrogen refueling stations (HRSs) have drawn attention from all social circles. However, hindered by various barriers, the development of HRSs is much slower than the Chinese government's expectation. Hence, this study aims to explore critical barriers of the HRS development in China based on a modified fuzzy decision-making trial and evaluation laboratory (DEMATEL) method. Firstly, a barrier list is identified through a literature survey and expert consultation, which consists of four categories (economic, technological, social and political-regulatory aspect) and 12 potential barriers. Later, considering the subjectivity of threshold setting in the traditional fuzzy DEMATEL method, the K-means clustering algorithm is utilized to optimize the threshold value, and thus a modified fuzzy DEMATEL approach is proposed to investigate the prominence of these barriers and the cause-effect relationships among them. The results show that six barriers are regarded as key barriers to China's HRS development, and corresponding policy measures are formulated to mitigate or eliminate these critical barriers.
Feasibility of incorporating autoclaved aerated concrete waste for cement replacement in sustainable building materials

Autoclaved aerated concrete waste (AACW) is a common low-strength cement-based construction and demolition waste, which is currently disposed by landfills and hard to be directly used as supplementary cementitious material. The present work proposed a potential approach incorporating AACW for cement substitution in sustainable building materials. Wet-milling technique was used to dispose and improve the fineness of AACW (median particle size, as low as 2.3 mu m). It was proved that AACW is suitable for wet-milling treatment due to its porous texture and low-strength. The pH value and electrical conductivity of the AACW slurry was notably improved. Water requirement was increased by the ultrafine AACW. Both setting time and the main hydration heat location were obviously brought forward by ultrafine AACW, indicating its early hydration acceleration. Compressive strength of ultrafine AACW replaced cement pastes present higher or equivalent value compared with pure cement paste, within 30% replacement level. Pore structure was effectively refined by the ultrafine wet-milling AACW. It was proved that AACW could be efficiently used as an alternative cementitious material in cement and concrete after wet-milling treatment, thus bring environmental and economic benefits. (C) 2019 Elsevier Ltd. All rights reserved.
Thermal optimization of shell and tube heat exchanger using porous baffles

In this study, total heat transfer rate and pressure drop along a shell and tube heat exchanger (STHX) with 6 porous baffles are numerically investigated. To study the impacts of segmental porous baffles, three values for the permeability (10(-9) m(2), 10(-12) m(2), and 10(-15) m(2)), porosity (0.2, 0.5, and 0.8), and baffle cut (25%, 35%, 50%) were considered, and the output parameters were calculated. Low baffle cuts provided the highest heat transfer; however, it generated a considerable amount of pressure drop as well. Although the porosity of 0.2 was superior in terms of heat transfer, higher pressure drop at lower baffle cut is the obstacle to consider it as the optimum value. The data was then utilized to train an Artificial Neural Network (ANN) to characterize the STHX and perform the sensitivity analysis. Baffle cut had the highest impact on the heat transfer as well as pressure drop while the porosity had the least in both by having 5% contribution. Finally, using genetic algorithm (GA), the optimum values for permeability, porosity, and baffle cut are calculated to gain the maximum heat transfer and minimum pressure drop in the system.
Computational model to explore the endocrine response to trastuzumab action in HER-2/neu positive breast cancer

Breast cancer is a very frequent type of cancer and much attention is paid to therapy with considerable efforts both in the pharmacological and clinical fields.The present work aims to create a non-linear dynamic model of action of the drug Trastuzumab against HER-2 + breast cancer, mainly considering its action of ADCP (antibody-dependent phagocytosis) killing of cancer cells. The model, while also considering the other therapeutic effects induced by Trastuzumab, shows how the action of this monoclonal antibody in the induction of ADCP through the action of macrophages, is strictly connected to the formation of a multi-complex "Trastuzumab -HER-2 - macrophage" that shows a prolonged action over time, responsible for the increase in the Overall Survivor (OS) parameter reported in various. The model shows the correlation between the various therapeutic effects and the killing action of cancer cells through the variation of the dynamic fluctuation of the representative "c" parameter.
Dominant follicle and gonadotropin dynamics before ovulation in postpartum lactating mares

The aim of this study was to compare the dominant follicle (DF) and gonadotropin dynamics for 9 days before ovulation in postpartum lactating (PP Lactating) versus non-postpartum cycling (N-PP Cycling) mares. Every PP Lactating mare on the day of parturition was paired with a N-PP Cycling mare, and the data analyses considered the partum-ovulation interval (POI) and the postpartum interovulatory interval (PPIOI) in PP Lactating mares and two interovulatory intervals in N-PP Cycling mares. The results of the present study revealed several novel and unique aspects of DF development and FSH and LH dynamics before ovulation in PP Lactating mares when compared with N-PP Cycling mares. The most remarkable differences between both groups of mares were the following: (1) a shorter interval to ovulation in PP Lactating mares during the foal heat (POI ≤22 days) compared with all other intervals; (2) a larger DF in PP Lactating mares, and an earlier day of DF at maximum diameter during the foal heat; and (3) lower gonadotropin levels in PP Lactating mares. Regarding the particularities, PP Lactating mares had lower LH levels during the POI than the PPIOI, demonstrating a strong partum effect; spring-foaled mares had longer POIs, larger DF diameters, and lower LH levels; and lower body condition scores and higher body-weight loss led to longer POIs and smaller DF diameters in PP Lactating mares. This study contributes to a broad understanding of ovarian function in the postpartum mare.
The use of black pepper (Piper guineense) as an ecofriendly antimicrobial agent to fight foodborne microorganisms

Consumers demand clean-label food products, necessitating the search for new, natural antimicrobials to meet this demand while ensuring food safety. This review aimed at investigating the antimicrobial properties of black pepper (Piper guineense) against foodborne microorganisms. The existence of foodborne illness, food spoilage, food waste, the resulting negative economic impact of these issues, and consumer interests have all pushed the food industry to find alternative, safe, and natural antimicrobials to be used in foods and beverages. Consumers have also influenced the demand for novel antimicrobials due to the perceived association of current synthetic preservatives with diseases and adverse effects on children. They also have a desire for clean-label products. These combined concerns have prompted researchers at investigating plant extracts as potential sources for antimicrobials. Plants possess many antimicrobial properties; therefore, evaluating these plant extracts as a natural source of antimicrobials can lead to a preventative control method in reducing foodborne illness and food spoilage, inclusively meeting consumer needs. In most regions, P. guineense is commonly utilized due to its potent and effective medicinal properties against foodborne microorganisms.
Testing the role of aerobic exercise in the treatment of posttraumatic stress disorder (PTSD) symptoms in U.S. active duty military personnel: a pilot study

The purpose of this pilot study was to determine if the efficacy of imaginal exposure for symptoms of posttraumatic stress disorder (PTSD) could be improved by adding aerobic exercise. We hypothesized that aerobic exercise would enhance the efficacy of exposure therapy. Active duty service members with clinically significant symptoms of posttraumatic stress (PTSD Checklist-Stressor-Specific Version, [PCL-S], ≥25) were randomized into one of four conditions: exercise only; imaginal exposure only; imaginal exposure plus exercise; no exercise/no exposure therapy (control). Participants (N = 72) were primarily male, Army, noncommissioned officers ranging in age from 22 to 52. PTSD symptom severity decreased over time (p < .0001); however, there were no significant differences between the experimental conditions. The prediction that imaginal exposure augmented with aerobic exercise would be superior to either imaginal exposure alone or aerobic exercise alone was not supported, suggesting that engaging in exercise and imaginal exposure simultaneously may not be any better than engaging in either activity alone. A better understanding of individually administered and combined exercise and exposure therapy interventions for PTSD is warranted.
Dramatic decrease of flood frequency in the Mekong Delta due to river-bed mining and dyke construction

Here we present a proof of concept evaluation of the impacts of riverbed-mining on river-wetland connectivity by analyzing the temporal trends of the flood frequencies in the Vietnamese Mekong Delta (VMD), while accounting for the effect of dyke constructions. We focus on the Long Xuyen Quadrangle (LXQ), which is significant in terms of biodiversity and economic contribution to the VMD as it is one of the most important food baskets of Southeast Asia that depends on seasonal flooding. Our results indicate that the flood frequency in LXQ has decreased significantly over the past 20 years (1995-2015). Time-series analyses of water level data at Chau Doc, Tan Chau, and Can Tho stations confirmed that the overall descending trend is statistically significant (p-value < 0.001 and tau similar to 0.1). However, the river discharge at Kratie showed no significant trend (p-value = 0.98) over the same period. This indicates that the flood frequency is associated with the lowering of the riverbed (incision) other than climatic factors. The connectivity analysis also revealed a remarkable drop in the inundation duration after early 2000, which corresponds to the previous observations of the shifting shoreline of the VMD from construction to shrinking. Finally, regression and principal component analyses underpinned the strong causality between the riverbed-mining and the decreased seasonal flooding patterns in LXQ, while accounting for the effect of the dyke system over the last decades (R-2 = 0.75). This study offers compelling evidences on the relationship between sand-mining in the river and the disrupted flood regimes in VMD. The reduction in water and sediments that is necessary for sustaining current rates of agricultural production in the long term would endanger the livelihoods of millions of VMD inhabitants. (C) 2020 Elsevier B.V. All rights reserved.
Employment and child support outcomes among noncustodial fathers: An evaluation of the Fathers Advancing Community Together program

Prior research underscores the importance of fathers' involvement in their children's lives. However, there is mixed evidence about the degree to which fatherhood programs improve economic stability and child support outcomes among noncustodial fathers. We attempted to address some of these gaps in the literature by evaluating the Fathers Advancing Community Together (FACT) program. FACT was implemented by Rubicon Programs, a community-based nonprofit organization in the Bay Area, California known for providing services to help move people out of poverty. The program provided parents economic stability, responsible parenting, and healthy relationship workshops, as well as support services and intensive case management. We relied on data from the Department of Child Support Services to assess whether FACT increased the likelihood of employment, child support modifications, and child support payments among noncustodial fathers during a 6-month post-enrollment period. Using 3:1 coarsened exact matching procedures, the total sample resulted in 744 fathers (186 in the intervention group and 558 in the comparison group). Results from logistic regression models indicate that FACT participants were more likely to be employed and more likely to receive a child support modification during the post-enrollment period than their comparison counterparts, though we found no significant relationship between FACT participation and whether fathers made a child support payment.
Five Tips for Becoming an Ideal General Hospitalist

Owing to the social structure issues caused by Japan's super-aged society, health-care roles have become more complex, and the need for general physicians has increased. General hospitalists in Japan perform various roles. Thus, the ideal image of general hospitalists there has been unclear. We summarize the 10 key skills for Japanese hospitalists indicated in the specialty programs of the Japanese Society of Hospital General Medicine. We identified the following five crucial points for ideal general hospitalists: general mindset; leadership and management; community-based comprehensive care and cooperation with various professions; appropriate medical interviewing, physical examination, and diagnostic reasoning; and proactive education and academic activities. This paper presents five tips, which deal with why those items are necessary and how they should be learned.
Changing the urban design of cities for health: The superblock model

Background: Car-dependent city planning has resulted in high levels of environmental pollution, sedentary lifestyles and increased vulnerability to the effects of climate change. The Barcelona Superblock model is an innovative urban and transport planning strategy that aims to reclaim public space for people, reduce motorized transport, promote sustainable mobility and active lifestyles, provide urban greening and mitigate effects of climate change. We estimated the health impacts of implementing this urban model across Barcelona. Methods: We carried out a quantitative health impact assessment (HIA) study for Barcelona residents >= 20 years (N= 1,301,827) on the projected Superblock area level (N= 503), following the comparative risk assessment methodology. We 1) estimated expected changes in (a) transport-related physical activity (PA), (b) air pollution (NO2), (c) road traffic noise, (d) green space, and (e) reduction of the urban heat island (UHI) effect through heat reductions; 2) scaled available risk estimates; and 3) calculated attributable health impact fractions. Estimated endpoints were preventable premature mortality, changes in life expectancy and economic impacts. Results: We estimated that 667 premature deaths (95% CI: 235-1,098) could be prevented annually through implementing the 503 Superblocks. The greatest number of preventable deaths could be attributed to reductions in NO2 (291, 95% PI: 0-838), followed by noise (163, 95% CI: 83-246), heat (117, 95% CI: 101-137), and green space development (60, 95% CI: 0-119). Increased PA for an estimated 65,000 persons shifting car/motorcycle trips to public and active transport resulted in 36 preventable deaths (95% CI: 26-50). The Superblocks were estimated to result in an average increase in life expectancy for the Barcelona adult population of almost 200 days (95% CI: 99-297), and result in an annual economic impact of 1.7 billion EUR (95% CI: 0.6-2.8). Discussion: The Barcelona Superblocks were estimated to help reduce harmful environmental exposures (i.e. air pollution, noise, and heat) while simultaneously increase PA levels and access to green space, and thereby provide substantial health benefits. For an equitable distribution of health benefits, the Superblocks should be implemented consistently across the entire city. Similar health benefits are expected for other cities that face similar challenges of environmental pollution, climate change vulnerability and low PA levels, by adopting the Barcelona Superblock model.
A Life Less than Ordinary: The Schooner Ocean (1821-1865)

The East Winner Bank Shipwreck takes its name from the southern sandbank on Hayling Island near Portsmouth, UK. Examination of the wreck indicates a 19th-century carvel-built vessel. The sandbank is an active environment, meaning the wreck is rarely exposed to its full extent. Discussed here is work completed on the site before and during the social-distancing restrictions imposed by COVID-19. Documentary sources and previous detailed surveys suggest a possible identification for the wreck. The site appears to be an example of an everyday 19th-century coastal trading vessel, rarely explored archaeologically in the UK, with potential to contribute to discussions of the maritime technologies and maritime cultural landscape of regular folk. The investigation represents an excellent example of combining historical and archaeological data sets to further the interpretation of both sources, revealing details about the ship and its lasting impact on this stretch of coastline.
Inhibitory effect of CC chemokine ligand 23 (CCL23)/ transcription factor activating enhancer binding protein 4 (TFAP4) on cell proliferation, invasion and angiogenesis in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is a highly vascularized solid tumor with a fast growth rate. According to bioinformatics analysis, CC chemokine ligand 23 (CCL23) has clinical significance for survival and prognosis in HCC. The online databases TCGA and CCLE were used to analyze the expression level of CCL23, and its expression was also measured in HCC cell lines by RT-qPCR and Western blotting. The STRING database and co-immunoprecipitation were employed to evaluate the association between CCL23 and transcription factor activating enhancer binding protein 4 (TFAP4). Overexpression plasmids for CCL23 (Ov-CCL23) and TFAP4 (Ov-TFAP4) were transfected into Huh-7 cells to detect TFAP4 expression. Huh-7 cells injected with OV-negative control (NC)/Ov-CCL23 or OV-NC/Ov-CCL23 plus Ov-TFAP4 were utilized to study the function of CCL23/TFAP4. Cell proliferation, invasion and human umbilical vein endothelial cell tube formation assays were conducted. The database revealed decreased expression of CCL23 in HCC and that it was commonly downregulated in HCC cell lines. TFAP4 expression was negatively correlated with CCL23. The overexpression of CCL23 inhibited the proliferation and invasion of Huh-7 cells, whereas TFAP4 blocked these effects. Similarly, the supernatant of CCL23-upregulated cells exhibited significantly lower tube formation potential, and low vascular endothelial growth factor A (VEGFA), VEGFRs expression compared with those of non-transfected Huh-7 cells, while TFAP4 plasmid co-transfected markedly increased these. Taken together, the present study suggests that CCL23 is expressed at low levels in HCC; it inhibits HCC cell proliferation, invasion and angiogenesis in vitro; and its action is negatively associated with and can be blocked by TFAP4.
European commitment to COP21 and the role of energy consumption, FDI, trade and economic complexity in sustaining economic growth

The nexus between economic growth and energy consumption has been exhaustively explored, yet the empirical evidence and the theoretical points of view remain at odds. This study contextualises and capitalises on this discrepancy and examines the connection between non-renewable and renewable energy consumption and economic growth, considering the moderating impact of economic complexity, trade openness, FDI and institutional quality. We use a panel quantile regression model and data from 32 European countries in the period 1995-2014. Our key results show that economic complexity, renewable energy consumption, trade openness, FDI and institutional quality enhance economic growth. The results for non-renewable energy consumption showed both a positive and a negative impact in different quantiles, indicating that the consumption of renewable energy is in fact more effective for economic growth than the use of non-renewables. Our findings have far-reaching implications for stakeholders and policymakers working on sustainable economic growth and energy policy with a view to meeting the commitments made under the Paris Agreement (COP21).
Chlorophyll- and anthocyanin-rich cell organelles affect light scattering in apple skin

Apple skin contains several groups of strongly absorbing cell organelles with pigments that change dynamically in type and concentration during fruit maturation. Chlorophylls and carotenoids, both primarily involved in photosynthesis, are found in the grana of chloroplasts, while anthocyanin vacuolar inclusions (AVIs) accumulate for light protection in red-skinned cultivars. A Mie model describing light scattering by absorbing spherical particles in a non-absorbing medium allowed to theoretically investigate the explicit influence of grana and AVIs on the effective scattering coefficient [Formula: see text] and the absorption coefficient [Formula: see text]. The reconstruction of the complex refractive indices of the organelles predicted anomalous dispersion, i.e., a local increase in the real part of the refractive index in the spectral regions with high chlorophyll and anthocyanin absorption, in agreement with the Kramers-Kronig relations. As a result, peaks in [Formula: see text] were predicted to be shifted to longer wavelengths compared to the corresponding [Formula: see text] bands. This selective scattering effect was confirmed experimentally with integrating sphere measurements for red- or green-skinned apple samples of the cultivars 'Elstar', 'Gala' or 'Jonagold'. Comparison between simulations and measurements indicated that the Soret bands of chlorophyll a and chlorophyll b are at 435 nm and 469 nm, respectively, and overlap with the absorption of carotenoids, whose red-most edge is at 488 nm. For anthocyanin absorption, a pronounced blue shift from 550 to 520 nm was observed, indicating structural or chemical changes of AVIs.