ahmedabdelwahed/Medical_papers_title_and_abstract_NLP_dataset huggingface dataset:
RESPIRE plus plus : Robust Indoor Sensor Placement Optimization Under Distance Uncertainty

Sensor placement in wireless sensor networks (WSN) aims to maximize coverage while minimizing total deployment cost. However, existing coverage-only approaches do not consider the robustness of the entire system where sensors may break down or malfunction. In this paper, we first propose a robustness-aware sensor placement approach by constructing a multi-objective optimization model. Our experiments demonstrate that this method increases the robustness of a WSN by up to 50%, with 201% higher probability of monitoring the entire environment as compared to the state-of-the-art coverage-only approach. The paper further improves the proposed method by introducing a robust optimization based sensor placement approach which considers the distance uncertainty between a sensor and a target. We show that this improved model increases the probability of target detection by up to 77% compared to state-of-the-art coverage-only approach.
In vitro antimicrobial effect of essential tea tree oil( Melaleuca alternifolia), thymol, and carvacrol on microorganisms isolated from cases of bovine clinical mastitis

Both Gram-negative and Gram-positive bacteria have recently developed antibiotic resistance to treatments for bovine mastitis, creating a serious concern for public and animal health. The objective of this study was to analyse in vitro microbicidal activity of tea tree oil, thymol and carvacrol (composed of oregano and thyme essential oils) on bacteria isolated from clinical mastitis. Field isolates and ATCC strains of the Staphylococcus spp, Streptococcus spp, Escherichia coli, Klebsiella pneumoniae, and Candida albicans genera were analysed. The agar diffusion technique was used to test bactericidal susceptibility and plate microdilution was utilized to determine the minimum inhibitory, bactericidal, and fractional inhibitory concentrations. Thymol alone and the combinations of thymol-carvacrol and thymol-TTO obtained the highest inhibition diameters for Gram-negative bacteria, while for Gram-positive bacteria and C. albicans, thymol and the combination thymol-carvacrol obtained the highest indices. TTO, thymol, and carvacrol had MIC values of 1.56-25 mg/ml, 0.05-0.4 mg/ml, and 0.02-0.2 mg/ml, respectively. CMB results for the Gram-negative and gram-positive groups were 0.39-0.78 mg/ml, and for C. albicans, 0.78-1.56 mg/ml. Results for the fractional inhibitory concentrations show that the TTO+thymol and thymol+carvacrol combinations had additive activity against groups of Gram-negative bacteria and C. albicans. These natural components, evaluated individually and in combinations, have an effectiveness above 70%.
From Childhood Maltreatment to Allostatic Load in Adulthood: The Role of Social Support

Although previous research has documented that social support acts as a protective factor for individuals exposed to trauma, most research relies on assessments of social support at one point in time. The present study used data from a prospective cohort design study to examine the stability of social support from childhood through middle adulthood in individuals with documented histories of childhood abuse and neglect and matched controls (aged 0-11) and assessed the impact of social support on allostatic load, a composite measure of physiological stress response assessed through blood tests and physical measurements, in middle adulthood. Maltreated children are more likely to have unstable social support across the life span, compared to matched controls. Social support across the life span partially mediated the relationship between child maltreatment and allostatic load in adulthood, although there were differences by race and sex. These findings have implications for interventions to prevent the negative consequences of child maltreatment.
The evolution of the reference monetary value of the man.sievert at electricite de France

The reference monetary value of the man.sievert is a pragmatic decision-aiding technique to "take into account economic and societal factors" associated with the optimisation principle and to help decide whether a protection option is "reasonable" or not. EDF has adopted a system of reference monetary values in 1992, updated it in 2002, and was considering a new update. In 2019 and 2020, a designated EDF-CEPN working group investigated the elements (through survey, literature and feedback analysis) that might support a change and in which direction. A simplified system, based on one single reference monetary value of the man.sievert, has been proposed. The value takes into account the most recent recommendations from ICRP and French State administration and uses the state-of-the-art methodology in calculating the Value of Statistical Life and has been adjusted with an aversion risk factor considering the EDF radiation protection policy. The new reference value is 4,500 euro/man.mSv. An upper value of 7,000 euro/man.mSv can be used if the project presents radiation protection benefits (positive externalities) in addition to a reduction in collective dose. The Radiation Protection Manager makes the decision on which value should be selected, and the Radiation Protection Service, in collaboration with the other services, integrates the value in the optimization analysis, bearing in mind that the output will guide the decision (and not determine it) bringing also objectivity and transparency.
Accurate modeling of replication rates in genome-wide association studies by accounting for Winner's Curse and study-specific heterogeneity

Genome-wide association studies (GWAS) have identified thousands of genetic variants associated with complex human traits, but only a fraction of variants identified in discovery studies achieve significance in replication studies. Replication in genome-wide association studies has been well-studied in the context of Winner's Curse, which is the inflation of effect size estimates for significant variants due to statistical chance. However, Winner's Curse is often not sufficient to explain lack of replication. Another reason why studies fail to replicate is that there are fundamental differences between the discovery and replication studies. A confounding factor can create the appearance of a significant finding while actually being an artifact that will not replicate in future studies. We propose a statistical framework that utilizes genome-wide association studies and replication studies to jointly model Winner's Curse and study-specific heterogeneity due to confounding factors. We apply this framework to 100 genome-wide association studies from the Human Genome-Wide Association Studies Catalog and observe that there is a large range in the level of estimated confounding. We demonstrate how this framework can be used to distinguish when studies fail to replicate due to statistical noise and when they fail due to confounding.
Food security for survivors of intimate partner violence: Understanding the role of food in survivor well-being

Intimate partner violence (IPV) and food security are two leading public health issues that disproportionately impact women in the United States. Despite this connection, the relationship between IPV and food security has been relatively unexplored. While food security is a known factor in increased well-being, it is not often explicitly included in care for survivors. As part of a larger study on survivors of domestic violence who are receiving services from a domestic violence and sexual assault agency in the Southern United States, we analysed participant responses (n = 26) to various scales (i.e. depression, anxiety, PTSD, disability, well-being, hope, food security) to determine the relationships between mental health and food-related variables. Importantly, findings from our study show that survivors experience low food security at higher rates (53.8%) than the U.S. national average (11.5%). Additionally, the proportion of survivors in our sample who are receiving some form of food aid and remain food insecure is high (26.9%), leading to questions about the adequacy of food aid. Finally, our results underpin the relationship between food security and mental health for survivors, as low food security is positively correlated with depression, PTSD, disability, trouble concentrating, lack of hope and decreased well-being. These findings have implications for how we evaluate food security and the role it plays in well-being for survivors.
Elastic Fibers/Fabrics for Wearables and Bioelectronics

Wearables and bioelectronics rely on breathable interface devices with bioaffinity, biocompatibility, and smart functionality for interactions between beings and things and the surrounding environment. Elastic fibers/fabrics with mechanical adaptivity to various deformations and complex substrates, are promising to act as fillers, carriers, substrates, dressings, and scaffolds in the construction of biointerfaces for the human body, skins, organs, and plants, realizing functions such as energy exchange, sensing, perception, augmented virtuality, health monitoring, disease diagnosis, and intervention therapy. This review summarizes and highlights the latest breakthroughs of elastic fibers/fabrics for wearables and bioelectronics, aiming to offer insights into elasticity mechanisms, production methods, and electrical components integration strategies with fibers/fabrics, presenting a profile of elastic fibers/fabrics for energy management, sensors, e-skins, thermal management, personal protection, wound healing, biosensing, and drug delivery. The trans-disciplinary application of elastic fibers/fabrics from wearables to biomedicine provides important inspiration for technology transplantation and function integration to adapt different application systems. As a discussion platform, here the main challenges and possible solutions in the field are proposed, hopefully can provide guidance for promoting the development of elastic e-textiles in consideration of the trade-off between mechanical/electrical performance, industrial-scale production, diverse environmental adaptivity, and multiscenario on-spot applications.
In vitro and in vivo antiviral activity of nucleoside analogue cHPMPC against African swine fever virus replication

African swine fever virus (ASFV) causes a haemorrhagic disease affecting wild boar and domestic pigs which can result in morbidity and fatality rates of up to 100%. ASFV is a large double-stranded DNA virus which replicates predominantly in the cell cytoplasm and codes for its replication and transcription machinery. No vaccine is widely available and control depends on early detection, culling of infected herds and adherence to biosecurity measures. In this study the small molecule nucleoside analogue, cyclic cidofovir (cHPMPC), was evaluated for its ability to inhibit replication of four different ASFV genotypes in primary porcine macrophages. Time of addition studies demonstrated that cHPMPC effectively inhibits ASFV replication and late gene expression when added pre-infection or early post-infection but not when added at late times, suggesting the drug target may be the virus DNA polymerase, or the RNA polymerase involved in late transcription. Oral administration of cHPMPC delayed onset of clinical signs and significantly reduced viral titres in blood and tissues of treated pigs. These results indicate that cHPMPC is a promising compound for further development to control ASFV outbreaks.
Delayed Treatment for People Living with HIV in China, 2004-2016: An Analysis of An Observational Cohort

Early universal access to antiretroviral treatment (ART) is critical in the control of the HIV epidemic. However, prompt initiation of ART remains problematic in China. This study analyzed the late testing and lag time between HIV diagnosis and initiation of ART from 2004 to 2016 and identified the risk factors for delayed initiation of ART. Data from 16,957 people living with HIV were abstracted from a hospital electronic health record database and a case report database for AIDS prevention and control in Yunnan province. Reasons for delayed initiation of ART were categorized into late testing, defined as CD4 count of < 350 cells/mu L at baseline HIV diagnosis, and delayed access, defined as a lag time of > 1 month between the diagnosis and initiation of ART. Binary logistic regression models were used to identify risk factors for late testing and delayed access. The CD4 counts at diagnosis increased from 201 +/- 147 cells/mu L (mean +/- SD) in 2004 to 324 +/- 238 cells/mu L in 2016 (p = 0.024). The CD4 count was higher for persons < 45 years, unmarried, and men who have sex with men (MSM) (356, 357, and 409 cells/mu L, respectively) compared to their peers in 2016 (p < 0.05). The lag time from diagnosis to initiation of ART was significantly reduced from 59.2 months in 2004 to 0.9 months in 2016 (p < 0.05). The shorter lag time over the years was consistent when analysis was stratified by sex, age, marital status, and transmission routes, even though the lag time for people using drugs was longest in 2016 (> 2 months versus 0.82 and 0.72 month of heterosexuals and MSM, respectively). Compared to their peers, married persons (AOR = 0.63, 95%CI: 0.57, 0.69) were less likely to have delayed access to ART, and drugs-using patients (AOR = 3.58, 95%CI: 2.95,4.33) were more likely to have delayed access to ART. Late testing rather than delayed access to ART after a diagnosis remains problematic in China, although improvements have been seen for both parameters from 2004 to 2016. Our data highlight the importance of continued efforts to promote early diagnosis of HIV to prevent transmission, morbidity, and early mortality in HIV infection.
Maternal Education Potentially Moderates the MAOA uVNTR Effects on Externalizing Behavior in Black South African Children

Interactions between the MAOA uVNTR and rearing environment are suggested to influence the developmental manifestations of childhood internalizing and externalizing behavior. However, few studies in the MAOA literature have included continental African children, or focused on non-clinical samples. We explored the main and interactive effects of the MAOA uVNTR (high and low activity alleles) in Black South African male (n = 478) and female (n = 540) children who were part of the longitudinal Birth to Twenty Plus cohort. Historical data on birth weight, gestational age at delivery, socioeconomic status, and maternal education were combined with genotypic information and analyzed using regression modeling. We found no significant main effects for the MAOA uVNTR on childhood behavior in either sex. A significant interaction (p = .04) was identified between MAOA and maternal education, suggesting that externalizing behavior in boys carrying a low activity MAOA allele varied in direct proportion to the education levels of their mothers. However, the model fit failed to reach significance, possibly due to our inclusion of only non-clinical pre-pubertal males. No significant interactions were detected for female children. Our findings lend tentative credibility to the Environmental Sensitivity metaframework, which suggests that MAOA is an important plasticity factor in childhood development.
Association between antimicrobial resistance and biofilm forming ability of Salmonella enterica serotypes from commercial broiler farms in Brazil

1. This study determined the antimicrobial resistance profile and the biofilm-forming ability of Salmonella enterica strains isolated from commercial broiler houses over a three-year period in southern Brazil.2. Of the 720 drag swabs analysed, 37 (5%) tested positive for non-typhoidal Salmonella spp. and S. Heidelberg was the most frequent serovar.3. Among the antimicrobial resistant strains (83.8%; 31/37), resistance was most common to tetracycline, ampicillin and nalidixic acid. Multidrug resistance was found in 65% (24/37) of the isolates, with a large proportion of multidrug resistant S. Heidelberg strains (81%; 13/16).4. In total, 65% (24/37) of the isolates showed the ability to produce biofilm and multiple antimicrobial resistance was negatively correlated with biofilm formation.5. Strains susceptible to all tested antimicrobials tended to form stronger biofilms than multidrug resistant ones. This suggested that Salmonella spp. with less antimicrobial resistance depend more on the protection provided by biofilm to survive in the farm environment.
Advanced Energy Flow Control Concept of an MMC for Unrestricted Operation as a Multiport Device

An advanced approach of the internal energy flow control of a multiport device based on a modular multilevel converter (MMC) was proposed. Such a multiport device offers various connecting points as ac terminals, the main de terminal as well as the dc terminals of the MMC modules. State-of-the-art multiport concepts have restrictions concerning the flexibility of connecting the available ports. The proposed concept makes an unrestricted energy interchange between all ports possible without affecting the ac grid and the main de terminal. It contains a microscopic and macroscopic view of the entire system and an analytic description in a double synchronous reference frame. This approach allows the identification of degrees of freedom for the internal energy flow control to overcome the mentioned restrictions of state-of-the-art multiport devices. Beyond numerous simulations calculations, the proposed concept has been implemented to a prototype of a multiport device which consists of an MMC with integrated batteries in power electronics laboratory. The approach has been successfully tested and verified with measurement results.
DSSN: dual shallow Siamese network for fashion image retrieval

Image retrieval is a way to search similar images from a given query image. The method successfully applied to different fashion image retrieval over different garments and footwear. However, research over complex fashion products such as ornaments have not got much momentum due to the complex nature of similarity and unavailability of suitable datasets. In this paper we have proposed a Dual Shallow Siamese Network (DSSN) for the task. The model has two identical Siamese networks and takes the same images as input but in a different representation. One subnetwork takes input as RGB color images and the other as identical segmented images. First, the networks are trained using positive and negative image pairs. Next, the trained model is used to find the difference between gallery and query images. The similarity score of the Siamese networks are then fused using weighted averaging. The method is applied on two public datasets, namely, RingFIR (earring dataset) and UT-Zap50K (footwear dataset). We have compared the retrieval accuracy of our method with other state-of-the-art image retrieval methods. The result shows that our method outperforms state-of-the-art methods. The source code and dataset is available publicly (https://github.com/skarifahmed/DSSN).
Promoting the Catalytic Ozonation of Toluene by Introducing SO42- into the α-MnO2/ZSM-5 Catalyst to Tune Both Oxygen Vacancies and Acid Sites

Mn-based catalysts hold the promise of practical applications in catalytic ozonation of toluene at room temperature, yet improvement of toluene conversion and COx selectivity remains challenging. Here, an innovative α-MnO2/ZSM-5 catalyst modified with SO42- was successfully prepared, and both characterizations and density functional theory (DFT) calculations showed that SO42- introduction facilitated the formation of oxygen vacancies, Lewis and Brönsted acid sites, and active oxygen species and enhanced the adsorption ability of toluene on α-MnO2/ZSM-5. Characterizations also showed that SO42- introduction made the catalyst possess larger specific surface area, superior reducibility, and stronger surface acidity. As a result, α-MnO2/ZSM-5 with a S/Mn molar ratio of 0.019 exhibited the best toluene conversion and COx selectivity, 87 and 94%, respectively, after the reaction for 8 h at 30 °C under an initial concentration of 5 ppm toluene and 45 ppm ozone, relative humidity of 45%, and space velocity of 32,000 h-1, far superior to those of non-noble catalysts reported to date under comparable reaction conditions. The synergistic role of increased oxygen vacancies and acid sites of α-MnO2/ZSM-5 modified with SO42- resulted in excellent toluene conversion and COx selectivity. The findings represented a critical step toward the rational design and synthesis of highly efficient catalysts for catalytic ozonation of toluene.
Management of Spontaneous Major Rectus Sheath Hematoma in a COVID-19 Patient: A Case Report and Literature Review

A rectus sheath hematoma, which is mostly encountered due to abdominal traumas or anticoagulant use, can be challenging, and a delayed diagnosis may lead to hypovolemic shock and even death. In this study, we aimed to present the management of a case of rectus sheath hematoma that developed in a patient who was hospitalized and under coronavirus disease 2019 (COVID-19) treatment. A 70-year-old female patient was admitted to the intensive care unit (ICU) due to respiratory failure and developed a sudden onset of tachycardia and hypotension. The patient was then diagnosed with a rectus sheath hematoma and after ensuring hemodynamic stability she was treated with angiographic embolization. Following the treatment, the patient remained hemodynamically stable and a control computed tomography (CT) revealed regression in the hematoma. Rectus sheath hematomas especially accompanied by additional comorbidities or aggressive surgical interventions may result in high mortality rates in the early period. It should also be kept in mind that during the COVID-19 pandemic, which has affected the world in the last two years, rectus sheath hematomas may be the underlying cause of sudden hypotension and abdominal distension, and it should not be forgotten that angiographic embolization performed by experienced interventional radiologists is the mainstay of treatment in cases where hemodynamic stability can't be achieved.
High-Speed Photonics for Side-by-Side Integration With Billion Transistor Circuits in Unmodified CMOS Processes

The performance of modern computer systems is limited by the input/output bottleneck problem. Key figures such as bandwidth density, energy efficiency, and reach are compared with state-of-the-art solutions. The latest photonic device library for computercom in the 45 nm silicon-on-insulator (SOI) node is reviewed. It is shown that monolithic integration of photonics and electronics in advanced CMOS nodes offers orders-of-magnitude better figures than standard wirelines and silicon photonic devices for datacom.