ahmedabdelwahed/Medical_papers_title_and_abstract_NLP_dataset huggingface dataset:
Modelling reverse supply chain through system dynamics for realizing the transition towards the circular economy: A case study on electric vehicle batteries

Circular economy (CE) is increasingly recognized as an issue of critical importance for companies, academics, practitioners, policymakers, and society as a whole. A successful transition from the current, linear economic model towards a resource-efficient circular economy model requires a shared understanding of the interplay among the building blocks of circular economy and the interaction among various decision factors. This research aims to explore these dynamics using environmental, societal, and economic aspects from a reverse supply chain perspective. This paper presents a model to represent the complex system of reverse logistics to recover post-used products at their end-of-life (EoL) stage. A system dynamics (SD) approach is used to model the dynamics of cost, revenue, and strategic and regulatory decisions. In addition, the interplay among the main pillars of circular economy research is explored through a case study of electric vehicle batteries (EVBs). Moreover, the main enablers and challenges for recovery of end-of-life batteries are presented. The findings show the importance of a shared understanding to achieve a successful transition towards a resource-efficient and circular economy model. Furthermore, reuse strategies such as remanufacturing and repurposing present a huge market potential for the recovery of electric vehicle batteries in the near future. (C) 2020 Elsevier Ltd. All rights reserved.
Design of fractional order PID controller for load frequency control system with communication delay

This work explores a frequency-domain approach to design a fractional order proportional-integral-derivative (FO-PID) controller cascaded with a first-order filter for the load frequency control (LFC) system with communication delay. The proposed method is based on suitable reference model development in the direct synthesis (DS) approach, followed by frequency response matching technique. The reference model is developed for robust control-loop performance using the stability-margin and time-domain specifications. The values of the fractional orders of the integral and derivative terms are obtained according to the dynamics of the nominal system. The proposed controllers have been designed for some LFC systems taken from the literature that have different dynamics with reheat, non-reheat and hydraulic turbines and performances with non-linearity like generation rate constraint (GRC), generation dead band (GDB) along with noise have been compared favorably with that of some controllers prevalent in the literature. The proposed controllers have been shown to work efficaciously for the decentralized multi-area IEEE 39-bus New England test system along with variable communication delay. To show the efficacy of the proposed controllers the load-disturbance responses along with the frequency and time domain performance indices have been evaluated for comparison.
An optimised grey buffer operator for forecasting the production and sales of new energy vehicles in China

In recent years, under a series of policy shocks, the production and sales of new energy vehicles in China show the characteristics of trend mutation and non-smoothness. In order to forecast the production and sales of new energy vehicles in China, an optimised grey buffer operator is proposed by introducing accumulation and translation transformations. Meanwhile, a genetic algorithm is employed to ascertain its optimum parameters. Forecasting results indicate that the optimised buffer operator can significantly improve the adaptability of the grey model to the production and sales data of new energy vehicles in China, and exhibits much higher prediction accuracy than those of the classical buffer operator and grey model. Besides, the prediction results show that the production and sales of China's new energy vehicles will continue to grow from 2018 to 2020, with an average annual growth rate of 27.53% and 30.49%, respectively. (C) 2019 Elsevier B.V. All rights reserved.
Partial replacement of copper slag with treated crumb rubber aggregates in alkali-activated slag mortar

Copper slag (CS) is an industrial waste, which is generally disposed of in landfills, posing threats to the environment. Alternatively, it can be used as natural aggregate replacement in concrete/m ortar, however, it results in a significant increase in material density, production and handling cost. The use of crumb rubber in combination with CS can overcome these problems, but there was no prior study on effect of such combination on the properties of alkali activated mortars (AAMs). The primary aim of this study is to address the problem stated above by replacing CS with 5, 10, 15% (by volume) crumb rubber in alkaliactivated slag mortars. Furthermore, the effect of pre-treatm ent of crumb rubber aggregates with sodium hydroxide (NaOH) solution for 1 h and 2 4 h on workability, compressive strength, flexural strength, w ater absorption, thermal conductivity, and microstructural properties of mortar mixes was investigated. Based on the test results, the use of crumb rubber resulted in inferior workability and mechanical strength, but better thermal insulating capability as compared to the control mix. Alkali treatm ent promoted the rubber-binder bond and effectively enhanced the strength of mixes, especially at an early-age (up to 59%), however, alkali treatm ent for 2 4 h drastically reduced the workability of fresh mix. Thus, it is recommended to use 10% crumb rubber pre-soaked in NaOH solution for 1 h to achieve acceptable performance. Finally, the economic and ecological analysis results revealed that the produced m ortar is beneficial to the environment. (C) 2020 Elsevier Ltd. All rights reserved.
Prehospital Supraglottic Airways: An NAEMSP Position Statement and Resource Document

Supraglottic airway (SGA) devices provide effective conduits for oxygenation and ventilation and may offer protection from gastric aspiration. SGA devices are widely used by EMS clinicians as both rescue and primary airway management devices. While in common use for more than four decades, major developments in SGA education, science, and technology have influenced clinical strategies of SGA insertion and use in prehospital airway management for patients of all ages. NAEMSP recommends:SGAs have utility as a primary or secondary EMS airway intervention. EMS agencies should select SGA strategies that best suit available resources and local clinician skillset, as well as the nature of their clinical practice setting.EMS agencies that perform endotracheal intubation must also equip their clinicians with SGA devices and ensure adequate training and competence.In select situations, drug-assisted airway management may be used by properly credentialed EMS clinicians to facilitate SGA insertion.Confirmation of initial and continuous SGA placement using waveform capnography is strongly encouraged as a best practice.When it is functioning properly, EMS clinicians should refrain from converting an SGA to an endotracheal tube. The decision to convert an SGA to an endotracheal tube must consider the patient's condition, the effectiveness of SGA ventilations, and the clinical context and course of initial SGA insertionSGA training, competency, and clinical use must be continuously evaluated by EMS agencies using focused quality management programs.
Effect of the Lipid Fraction of Microalgae on Biochemical Parameters in Female C57BL/6 Mice

We studied the effect of microalgae of various systematic groups added to the ration on the biochemical parameters of blood serum and liver and kidney tissue in rats. It was found that microalgae had different effects on the levels of proteins, lipids, and sex hormones, activity of aminotransaminases, and filtration capacity of the kidneys. Microalgae also affected the biochemical parameters of the liver and kidney tissues.
Anthelmintic potency of Rumex crispus L. extracts against Caenorhabditis elegans and non-targeted identification of the bioactive compounds

Traditional healers and ethnoveterinary therapists use several medicinal plants, such as Rumex crispus L., to treat endoparasite infections. R. crispus has been established by researchers to be effective agasint a few parasitic worms. In this study, we evaluated the potency of R. crispus extracts on the model organism, Caenorhabditis elegans and the bioactive compounds of the extracts were also identified. The solvent extracts of R. crispus were tested against C. elegans for up to 72 h. The effect of the extracts on C. elegans was examined using light microscopy (LM) and scanning electron microscopy (SEM). LM and SEM analysis showed damage on the body wall, reduced body and slight modifications of the nematode organs. The lethality test reveals a significant reduction in the viability of the nematode with the water extract of leaf (LF-WAE), among others, having the strongest potency against the nematode, with 83% lethality. Anlysis done with Fourier-transform infrared spectroscopy (FTIR) spectra reveals various characteristic vibration bands and fingerprint bands at 3400-600 cm-1, identifying phenols, organic acids, aromatics, amines, among others in the plant. The compounds were identified with liquid chromatography-mass spectrometry (LC-MS), under the categories of flavonoids, steroidal alkaloids and proanthocyanidin. In conclusion, this study confirmed that R. crispus has anthelmintic potential, using standardised C. elegans models as a tool and suggests that there could be novel compounds yet to be explored in the studied plant that could be of great benefit to livestock and humans.
The spatial effect of tourism economic development on regional ecological efficiency

The process of tourism economic development is accompanied by the consumption of energy and environment. It is of a big significance to measure the level of tourism economic development and regional eco-efficiency correctly to clarify the relationship between them, as it contributes to realizing the high-quality development of the tourism economy and the construction of "beautiful China". On the basis of the panel data of China's 30 provinces and cities from 2002 to 2016, the paper intends to evaluate the regional eco-efficiency and tourism economic development level by using the super-efficiency DEA model and the grey entropy weight method, and then construct spatial panel econometric model which is based on the previous data to deeply discuss the influence of tourism economy development on regional ecological efficiency and its spatial effect. The research shows that (1) regional ecological efficiency has significant spatial dependence and spatial aggregation characteristics. With the passing of time, this kind of positive spatial autocorrelation is gradually strengthened. (2) In the long-term development, tourism economic development and regional ecological efficiency show a more obvious "Kuznets curve" effect. (3) The "U"-curve relationship between urbanization, environmental regulation, and regional eco-efficiency was confirmed. (4) In the process of tourism economic transformation and development, industrial pollution control, environmental regulation, technological level, urbanization, and investment openness are the main factors that affect the improvement of ecological efficiency in the local region. (5) Tourism economic development and urbanization levels have different spatial spillover effects in different periods, while investment openness has obvious positive spillover effects.
Impact of foreign trade on energy efficiency in China's textile industry

Improving energy efficiency is important to ensure economic growth while conserving energy and reducing emissions. Based on the total factor energy efficiency of China's textile industry, this paper constructs a simultaneous equation model that includes the Tobit model, and empirically analyzes whether foreign trade affects energy efficiency in the textile industry as well as the mechanism of any such influence. The empirical results demonstrate positive feedback between foreign trade and energy efficiency in the textile industry, with imports impacting energy efficiency more than do exports. The foreign trade of textile industry is divided into import trade and export trade, which have different impacts on energy efficiency. Simultaneously, the results also confirm that R&D input, ownership structure and energy price significantly impact the energy efficiency of China's textile industry. (C) 2019 Elsevier Ltd. All rights reserved.
Circular RNA Plasmacytoma Variant Translocation 1 (CircPVT1) knockdown ameliorates hypoxia-induced bladder fibrosis by regulating the miR-203/Suppressor of Cytokine Signaling 3 (SOCS3) signaling axis

The effects of circular RNAs (circRNAs) on bladder outlet obstruction (BOO)-induced hypertrophy and fibrogenesis in rats and hypoxia-induced bladder smooth muscle cell (BSMC) fibrosis remain unclear. This study aimed to determine the regulatory role of circRNAs in the phenotypic changes in BSMCs in BOO-induced rats.circRNAmicroarray and real-time PCR were used to explore differentiated expressed circRNAs. Bioinformatics analyses and dual-luciferase reporter were performed to identify the targets for circRNA PVT1 (circPVT1). BOO was performed to establish a bladder fibrosis animal model. The circPVT1 and suppressor of cytokine signaling 3 (SOCS3) expression levels were upregulated (p = 0.0061 and 0.0328, respectively), whereas the microRNA-203a (miR-203) level was downregulated in rats with bladder remodeling (p=0.0085). Bioinformatics analyses and dual-luciferase reporter assay results confirmed that circPVT1 sponges miR-203 and that the latter targets the 3'-untranslated region of SOCS3. Additionally, circPVT1 knockdown alleviated BOO-induced bladder hypertrophy and fibrogenesis. Furthermore, hypoxia was induced in BSMCs to establish a cell model of bladder fibrosis. Hypoxia induction in BSMCs resulted in upregulated circPVT1 and SOCS3 levels (p = 0.0052) and downregulated miR-203 levels. Transfection with circPVT1 and SOCS3 shRNA ameliorated hypoxia-induced transforming growth factor-β (TGF-β1), TGFβR1, α-smooth muscle actin, fibrotic growth factor, extracellular matrix subtypes, BSMC proliferation, and apoptosis-associated cell injury, whereas co-transfection with miR-203 inhibitor counteracted the effect of circPVT1 shRNA on these phenotypes.These findings revealed a novel circRNA regulator of BOO-associated bladder wall remodeling and hypoxia-induced phenotypic changes in BMSCs by targeting the miR-203-SOCS3 signaling axis.
Reduction of acute gastric volvulus in a 3-year-old using a balloon-attached endoscope combined with gel immersion endoscopy

When performing endoscopic reduction in patients with gastric volvulus, it is important to maintain a low level of intragastric pressure and to fix the endoscope in the duodenum. Gel immersion endoscopy is a new method for securing the visual field by injecting clear gel. The balloon-attached endoscope makes it easier to fix the tip in the duodenum without mucosal damage. We report successful reduction of a mesenteroaxial gastric volvulus using an endoscope with a balloon in combination with gel immersion endoscopy. A 3-year-old Japanese male developed gastric volvulus. Since gastric decompression using a nasogastric tube failed to reduce the volvulus, endoscopic reduction was performed under general anesthesia. After aspiration of intragastric gas, clear gel was injected through the accessory channel which secured the visual field in the stomach even with residue while maintaining low intragastric pressure. After reaching the descending portion of the duodenum, the balloon attached to the tip of the endoscope was inflated and fixed in the duodenum. The volvulus was successfully reduced by pulling back the endoscope with clockwise torque. Acute mesenteroaxial gastric volvulus has the potential to cause ischemia and perforation which can be life-threatening, so most patients are treated with surgical intervention. Gel immersion endoscopy is safe and effective to secure the visual field, even in children. Endoscopic reduction may be a viable treatment option for reducing gastric volvulus in non-emergent patients.
The impact of macroeconomic and financial development on carbon dioxide emissions in Pakistan: evidence with a novel dynamic simulated ARDL approach

This paper has empirically explored the impact of macroeconomic and financial development on CO(2)emissions by utilizing a novel dynamic simulated ARDL model for annual time series data from 1982 to 2018 for Pakistan. The results of a novel dynamic simulated ARDL disclosed that the growth of stock market, FDI, economic growth, and consumption of oil wield a positive impact on CO(2)emission, while domestic credit exerts a negative effect on CO(2)emission both in the short and the long run in Pakistan. The stock market development and domestic credit wield a significant influence on carbon dioxide emission in Pakistan both in the long and the short run. FDI exerts significant impact only in the long run, while economic growth and consumption of oil wield significant impact only in the short run on CO(2)emission in Pakistan. This study opens up new visions for the economy of Pakistan to sustain financial and economic growth by protecting environment from pollution through its efficient national environmental policy, fiscal policy, and monetary policy.
Low-dose oral isotretinoin for the treatment of adult patients with mild-to-moderate acne vulgaris: Systematic review and meta-analysis

Acne vulgaris is one of the most common dermatologic complaints. Recently, isotretinoin has been used as an off-label indication for the treatment of mild-to-moderate grades of acne not responding to conventional treatment. Its conventional recommended dose is 0.5-1.0 mg/kg per day to the cumulative dose of 120-150 mg/kg. To qualify the state of evidence and analyze the efficacy of the low-daily dose and the pulsed doses of isotretinoin in treating mild-to-moderate acne patients with regards to response and relapse rates. Systematic review and meta-analysis using an electronic literature search were performed. The 320 potentially relevant articles were included and reviewed. The level of evidence is moderate to low as conducted by the GRADE quality of evidence assessment. The pooled statistical estimate for response to treatment in the group comparing low-daily doses with conventional dose showed an overall benefit for conventional dose. On the other hand, pooled data from the group comparing the low-daily dose with the pulsed doses yielded an overall beneficial effect from using the low-daily dose compared with the pulsed doses on achieving the response. Given all of the available studies, the quality of evidence is low. It appears that conventional dose isotretinoin improves the odds of prolonged remission in adults with mild-to-moderate acne vulgaris compared to the low doses.
The Noctambuli: tales of sleepwalkers and secrets of the body in seventeenth-century England

Seventeenth-century readers were fascinated by marvellous tales of people known as the noctambuli who rose up in their sleep, performed daily chores and attempted dangerous feats, such as clambering onto rooftops. On account of their uncanny nature, commentators noted that sleepers could be mistaken for spectres or those who had been bewitched. Depictions of the noctamubli were also influenced by the Malleus Maleficarum, which had argued that they were acting under the influence of demons and would fall if their Christian name was called. Medical texts explained this behaviour in terms of the escape of hot vapours within the body, the powers of the imaginative faculty, and the impairment of common sense during sleep. While this explanation was widely accepted, in the 1650s it was challenged by alternative views from esoteric writings, which conceptualised the movements of sleepers in terms of mystical powers within the body.
Benign mixed Müllerian (duct) vaginal tumor in a 12-y-old goat

In human and veterinary medicine, mixed Müllerian tumors (MMTs) are rarely diagnosed neoplasms of the tubular female genital tract. Although there are case reports of malignant MMTs in various species, benign MMTs have only been described once in a macaque. Here we present a case of benign MMT in a 12-y-old goat, and review the literature on uterine, cervical, and vaginal neoplasia in goats. The doe was presented with vaginal discharge and was euthanized because of the high suspicion of intraabdominal neoplasia. On gross examination, an ulcerated vaginal mass was identified. Histologically, 2 distinct cell populations were present: smooth muscle cells that were well differentiated and positive for alpha-smooth muscle actin, and ciliated columnar epithelial cells that lined ductal structures and had no signs of malignancy. These findings led to the diagnosis of neoplasia of Müllerian origin. Benign MMT should be considered as a differential diagnosis for uterine and vaginal neoplasms in goats.
The risk of stent thrombosis of dual antithrombotic therapy for patients who require oral anticoagulant undergoing percutaneous coronary intervention: insights of a meta-analysis of randomized trials

Recent meta-analyses investigating dual antithrombotic therapy (DAT) versus triple antithrombotic therapy (TAT) among patients who require oral anticoagulants especially with atrial fibrillation (AF) undergoing percutaneous coronary intervention (PCI) raised the concern of stent thrombosis (ST) and myocardial infarction (MI), however, these meta-analyses did not include all randomized trials who require oral anticoagulants. We aimed to investigate the efficacy of DAT versus TAT in these patients undergoing PCI. Our data showed the risk of ST was not significantly different in DAT vs. TAT (HR [95%CI]: 1.50 [0.97-2.34], p = .07; I2 = 0%) and MI (HR [95%CI]: 1.17 [0.95-1.45], p = .14; I2 = 0%).
Prediction of biogas production rate from anaerobic hybrid reactor by artificial neural network and nonlinear regressions models

In the present study, a three-layer artificial neural network (ANN) and nonlinear regression models were developed to predict the performance of biogas production from the anaerobic hybrid reactor (AHR). Firstly, the performance of an AHR which is filled with perlite (2.38-4.36 mm) at fill rates of 1/3, 1/4 and 1/5 for the treatment of synthetic wastewater was investigated at a loading rate of 5, 7.5, 10, 12.5 and 15 kg COD m(-3) day with 12, 24, 36 and 48 h of hydraulic retention time (HRT) under mesophilic conditions (37 +/- 1 degrees C). In this study, experimental data were used to estimate the biogas production rate with models produced using both ANNs and nonlinear regression methods. Moreover, ten related variables, such as reactor fill ratio, influent pH, effluent pH, influent alkalinity, effluent alkalinity, organic loading rate, effluent chemical oxygen demand, effluent total suspended solids, effluent suspended solids and effluent volatile suspended solids, were selected as inputs of the model. Finally, ANN and nonlinear regression models describing the biogas production rate were developed. The R-2, IA, FA2, RMSE, MB for ANNs and nonlinear regression models were found to be 0.9852 and 0.9878, 0.9956 and 0.9945, 0.9973 and 0.9254, 217.4 and 332, 36 and 222, respectively. The statistical quality of ANNs and nonlinear regression models were found to be significant due to its high correlation between experimental and simulated biogas values. The ANN model generally showed greater potential in determining the relationship between input data and the biogas production rate according to statistical parameters (except R-2 and R). The results showed that the proposed ANNs and nonlinear regression models performed well in predicting the biogas production rate of AHR on behalf of avoiding economic and environmental sustainability problems. [GRAPHICS] .