ahmedabdelwahed/Medical_papers_title_and_abstract_NLP_dataset huggingface dataset:
CO2 emission in transportation sector across 51 countries along the Belt and Road from 2000 to 2014

The transportation sector is a key economic sector and an important source of CO2 emissions. Due to these environmental implications and a desire to reduce emission levels, the number of empirical analyses on the transportation sector have increased significantly in recent times. Given this pretext, our study examines the heterogeneity and spatial autocorrelation CO2 emissions of the transportation sector for 51 belt and road economies from 2000 to 2014. As part of analysis, we examine the heterogeneity of CO2 emissions in the transportation sector through the use of the Theil index and semi-variogram analysis. Furthermore, our study also analyzed the global and local spatial autocorrelation of transport sector CO2 emissions using the Moran index for participating countries. From the analysis, this study found that the transportation CO2 emission intensity of Central and Western Asia and North Africa is significantly higher than that of other regions along the belt and road, and there is a strong spatial correlation in Southeast Asian countries. Our research provides a key reference point for governments by proposing carbon-reduction policies and the promotion of greener developmental initiatives within the transportation sector. (C) 2020 Elsevier Ltd. All rights reserved.
Growth charts for Mexican children with Down syndrome

We present the results of a prospective, observational, descriptive, cross-sectional study performed on a Mexican population of 1867 children, aged 0-18 years, with Down syndrome (DS), observed between 2013 and 2019. A total of 9968 measurements of height, weight, and head circumference, as well as calculation of body mass index (BMI) were used to create growth charts and tables of percentiles. Growth curves were elaborated using Cole's LMS method. The mean weight and length at birth did not differ by sex: the weight was 2750 g for boys and 2710 g for girls (p > 0.05), and the length was 48.2 cm for boys and 47.9 cm for girls (p > 0.05). The mean final height at 18 years was different by sex: 149.6 cm for boys and 141.2 cm for girls. The average BMI at 18 years was 24.2 kg/m2 for boys and 21.9 kg/m2 for girls. In a comparison with U.S. growth charts, we find that the Mexican population has lower height and weight. These are the first growth curves for the Mexican population with DS. They can be used by health care providers to optimize preventive care by monitoring children with DS for the early identification of factors that affect individual growth.
A life cycle cost model for floating offshore wind farms

Over the last few decades, there has been a renewed interest in the offshore wind sector. In particular, floating wind turbines represent the next frontier in the wind power industry. Currently, only research prototypes exist, and few studies are available on their possible investment cost. Therefore, a cost assessment for this technology is necessary to ascertain whether it is economically sustainable. This paper develops a life cycle cost model for floating offshore wind farms, bringing together the most up-to-date data and parametric equations from data-bases and literature. The cost model considers the key parameters of the wind power economy, namely CAPEX, OPEX, DECEX and LCOE. The proposed model should be helpful for future decision-making, as the wind energy industry is in constant evolution. An application to an offshore floating wind farms is also carried out, in which the three main types of floaters are considered, namely the Semi-Submersible Platform, the Spar Buoy and the Tension Leg Platform. An average LCOE of 9.74 c/kWh was found, at the lower bound of the typical range applying to fixed base offshore wind farms, and higher than typical values applying to onshore wind farms.
Mining is bad for health: a voyage of discovery

Mining continues to be a dangerous activity, whether large-scale industrial mining or small-scale artisanal mining. Not only are there accidents, but exposure to dust and toxins, along with stress from the working environment or managerial pressures, give rise to a range of diseases that affect miners. I look at mining and health from various personal perspectives: that of the ordinary man (much of life depends on mined elements in the house, car and phone); as a member of the Society for Environmental Geochemistry and Health (environmental contamination and degradation leads to ill health in nearby communities); as a public health doctor (mining health is affected by many factors, usually acting in a mix, ranging from individual inheritance-genetic makeup, sex, age; personal choices-diet, lifestyle; living conditions-employment, war; social support-family, local community; environmental conditions-education, work; to national and international constraints-trade, economy, natural world); as a volunteer (mining health costs are not restricted to miners or industry but borne by everyone who partakes of mining benefits-all of us); and as a lay preacher (the current global economy concentrates on profit at the expense of the health of miners). Partnership working by academics with communities, government and industry should develop evidence-based solutions. Employment, health, economic stability and environmental protection need not be mutually exclusive. We all need to act.
Design and comparative exergy and exergo-economic analyses of a novel integrated Kalina cycle improved with fuel cell and thermoelectric module

Combined cooling, heating, and power systems (CCHP) have attracted a lot of attention due to their distinctive advantages of high system and economic efficiencies in addition to less greenhouse gas emissions. The current study investigates the performance of a Kalina cycle-based CCHP system in which geothermal energy is utilized as the low temperature source of prime energy. A thermoelectric generator is used in the system for retrieving wasted heat and producing extra amount of electricity thereby leading to higher overall efficiency. Two types of fluids, i.e. geothermal water and mixture of water-ammonia, are employed for the steam cycle and Kalina cycle, respectively. A comparative performance analysis is carried out on three system configurations, namely; basic Kalina cycle system, Kalina cycle with a thermoelectric generator (TEG), and Kalina cycle integrated with TEG and a Proton Exchange Membrane Fuel Cell (PEMFC). The results demonstrated that employing TEG increases the output power by 25.1 kW and improves cycle efficiency by 1.7%. Moreover, integrating both TEG and PEMFC increases the net output power of the proposed system to 1101 kW, which is 993.2 kW and 971.7 kW higher than the basic Kalina cycle system and the Kalina cycle system coupled with the TEG respectively. In addition, the exergy analysis of each component in the system showed that the condenser has the most exergy destruction. Multi-criteria optimization is applied to seek the optimum operation condition of the proposed system. The net output power and electricity cost were used as two critical optimization targets. An optimum condition of the system is suggested using the concept of ideal point on the Pareto front plot.
A new glimpse on the active site of SARS-CoV-2 3CLpro, coupled with drug repurposing study

Coronavirus disease 2019 (COVID-19) is caused by novel severe acute respiratory syndrome coronavirus (SARS-CoV-2). Its main protease, 3C-like protease (3CLpro), is an attractive target for drug design, due to its importance in virus replication. The analysis of the radial distribution function of 159 3CLpro structures reveals a high similarity index. A study of the catalytic pocket of 3CLpro with bound inhibitors reveals that the influence of the inhibitors is local, perturbing dominantly only residues in the active pocket. A machine learning based model with high predictive ability against SARS-CoV-2 3CLpro is designed and validated. The model is used to perform a drug-repurposing study, with the main aim to identify existing drugs with the highest 3CLpro inhibition power. Among antiviral agents, lopinavir, idoxuridine, paritaprevir, and favipiravir showed the highest inhibition potential. Enzyme - ligand interactions as a key ingredient for successful drug design.
Identifying stakeholders and discussing a strategy for the participatory management of a protected area: the case of Engenho Pequeno, in Rio de Janeiro State, Brazil

This paper identifies the potential main social actors involved in and affected by the conservation and use of the Environmental Protection Area (EPA) of Engenho Pequeno, in Rio de Janeiro State, Brazil, and discusses how environmental education can be shaped to engage them in participatory, socially progressive and environmentally sustainable management for that area. Therefore, semi-structured interviews were conducted with individuals and entities related to the EPA. The snowball method complemented the mapping of non-official social actors. The discussion was based on the critical approach of environmental education, polycentric governance, adaptive management, environmental advocacy and case studies about education in protected areas. Results showed nine key stakeholders to be considered in a network program for the EPA's participatory management, including government, schools, local and nearby residents and religious groups. In the end, we recommend the hosting of a one day workshop, built around existing local and national environmental goals, as an entry point for trust building and the search for shared interests.
The Effects of β-Pinene, a Pine Needle Oil Monoterpene, on Adenovirus Type 3

The mechanisms of the inhibitory action of β-pinene, a pine needle oil monoterpene, on human adenovirus type 3 were studied using cytopathic inhibition test, MTT test, atomic force and laser confocal microscopy. β-Pinene inhibited the viruses stronger that the reference antiviral medication ribavirin (p<0.05). Inhibition of viral cytopathic effect (CPE) increased with increasing the concentration of β-pinene, which attested to direct elimination of adenovirus type 3. During viral reproduction phase, β-pinene significantly inhibited proliferation of adenovirus type 3. Typical signs of adenoviral CPE as cell swelling and rounding were less pronounced in comparison with the control (ribavirin treatment). In addition, elevation of β-pinene concentration significantly increased the cell survival rate (p<0.05). Laser confocal microscopy showed that fluorescence intensity in the β-pinene group was significantly lower than in the control group (p<0.01), which was consistent with the results of MTT test, thereby providing additional arguments that β-pinene affects the virus during the absorption phase. Thus, β-pinene directly inactivates adenovirus type 3 and impedes its invasion into the cells, but produces no protective effects on cells. Understanding the mode of action of such monoterpenes as β-pinene is of great importance for the development of new antiviral drugs.
Household-based critical influence factors of biogas generation technology utilization: A case of Punjab province of Pakistan

This research comprehensively examined the contributions of households' critical influence factors (CRIFs) in BGT utilization. The data based on a sample of 695 households from seven selected districts of Punjab province of Pakistan. The empirical findings are: first, among the households' preference based CRIFs, cooking as a utilization mode imparted positive and significant influence on BGT utilization. It implicated that cooking was found to be the dominant preference of households to utilize the BGT. Moreover, the health risk factor was exposed to be important in BGT utilization. This is likely for people to attach importance to their health. Second, dual nature of the influence of gender is observed: (i) it emphasized the role of woman empowerment in choice of BGT, and also, (ii) as the females need to spend extra time in fuel collection, they want to switch to BGT. Third, concerning the socio-economic and infrastructural influence factors, the education of both household head and chef portrayed a positive influence on BGT utilization. Moreover, households with relatively more land ownership and livestock were more probable to utilize BGT. Finally, the users of the BGT experienced the financial, health, environmental protection, and crop harvest benefits as compared to non-users of BGT. (C) 2020 Elsevier Ltd. All rights reserved.
Surface Electrostatics Govern the Emulsion Stability of Biomolecular Condensates

Liquid-liquid phase separation underlies the formation of biological condensates. Physically, such systems are microemulsions that in general have a propensity to fuse and coalesce; however, many condensates persist as independent droplets in the test tube and inside cells. This stability is crucial for their function, but the physicochemical mechanisms that control the emulsion stability of condensates remain poorly understood. Here, by combining single-condensate zeta potential measurements, optical microscopy, tweezer experiments, and multiscale molecular modeling, we investigate how the nanoscale forces that sustain condensates impact their stability against fusion. By comparing peptide-RNA (PR25:PolyU) and proteinaceous (FUS) condensates, we show that a higher condensate surface charge correlates with a lower fusion propensity. Moreover, measurements of single condensate zeta potentials reveal that such systems can constitute classically stable emulsions. Taken together, these results highlight the role of passive stabilization mechanisms in protecting biomolecular condensates against coalescence.
Measuring environmental policy stringency: Approaches, validity, and impact on environmental innovation and energy efficiency

Solid tests of the impact of environmental and energy policy on important economic outcomes, such as innovation, productivity, competitiveness and energy and carbon efficiency are impaired by the lack of appropriate empirical proxies for the commitment to, and stringency of, environmental policy. We contribute to the literature by: (1) computing different indicators of environmental policy stringency, (2) testing to what extent they convey similar insights through a statistical comparison exercise, and (3) showing the implications of using one or the other indicator in two illustrative empirical applications focused on environmental innovation and energy efficiency. We conclude by highlighting the implications of our analysis for empirical research focusing on the evaluation of policy impacts, and highlight fruitful future research avenues.
Antihypertensive and cardioprotective effects of different monotherapies and combination therapies in young spontaneously hypertensive rats - A pilot study

Spontaneously hypertensive rats (SHR) are an established animal model for antihypertensive treatment. The aim of this pilot study was a systematic search for two lines of antihypertensive treatment - a monotherapy and a combination of two drugs - to be applied in a future study on old SHR. Originally, representatives of three drug classes recommended for antihypertensive therapy in humans should be applied, namely captopril (CAP) as an antagonist of the renin-angiotensin-aldosterone system, nifedipine (NIF) as calcium channel blocker and propranolol (PROP) as β-adrenergic blocker. As we observed that PROP had been poorly ingested, all groups with PROP therapy were excluded from the study. CAP (60 mg kg-1 d-1), NIF (10 mg kg-1 d-1) or both were administered orally to seven-week-old SHR over 3 weeks. A further group of SHR received no treatment (SHR/CTRL). Age-matched normotensive Wistar-Kyoto rats served as normotensive controls. We examined the effect of the antihypertensive therapies on systolic blood pressure, heart weight and on histological and biochemical markers of cardiac hypertrophy and fibrosis. CAP proved to be the most effective treatment reducing blood pressure and relative heart weight significantly compared to SHR/CTRL without reaching normotensive values. Beginning cardiac fibrosis observed in SHR/CTRL was completely abrogated with CAP treatment. Similar effects were achieved with a combination of CAP and NIF. CAP as monotherapy and CAP + NIF as combination therapy were chosen for the forthcoming study on old SHR.
Impact Assessment of COVID-19 on Variations of SO2, NO2, CO and AOD over East China

The COVID-19 (Coronavirus Disease 2019) broke out in the late of 2019. On January 23 in Wuhan, and later in all other cities of the country, there were taken measures to control the spread of the virus through quarantine measures. This article focused on East China and attempted to assess comprehensively the environmental impact of the COVID-19 outbreak. This study analyzed satellite observational data of sulfur dioxide (SO2), nitrogen dioxide (NO2), carbon monoxide (CO) and aerosol optical depth (AOD) in the period before the outbreak of the epidemic and during the implementation of preventive measures and control of COVID-19, as well as compared it with the data obtained in the same period of 2019. The results of the analysis showed that the COVID-19 lockdown improved air quality in the short term, but as soon as coal consumption at power plants and refineries returned to normal levels due to the resumption of their work, pollution levels returned to their previous level. The levels of CO and NO2 showed the most significant decrease (20 and 30%), since they were mainly associated with a decrease in economic growth and transport restrictions that led to a change in energy consumption and a reduction in emissions. This study can complement the scientific community and environmental protection policy makers, not only to assess the impact of outbreak on air quality, but also for its effectiveness as a simple alternative program of action to improve air quality.
Acute hemorrhage and death in calves following chlorophacinone exposure

Three calves were submitted to the Iowa State University Veterinary Diagnostic Laboratory for diagnostic evaluation following an abrupt increase in morbidity and mortality in a calf herd associated with epistaxis and widespread hemorrhage. Each of the submitted calves had moderate-to-severe hemorrhage within various tissues and body cavities, including the thymus, subcutaneous region of the neck, mediastinum, lungs, pericardial sac, heart, spleen, perirenal fat, urinary bladder, and skeletal muscle, including the diaphragm. An anticoagulant rodenticide screen was performed on the livers of each calf. Significant concentrations of chlorophacinone were detected at 4.2, 3.6, and 2.9 ppm in liver. Multiple piles and an open pail of white powdery material were present within the facility in which the calves were housed and were identified as the sources of chlorophacinone. Acute hemorrhage and death occurred in fourteen 1.5-mo-old, crossbred calves following ingestion of the vitamin K antagonist chlorophacinone.
Responding to the Essential Sexual and Reproductive Health Needs for Women During the COVID-19 Pandemic: A Literature Review

The pandemic and its consequences have been shown to have a negative impact on the availability and accessibility of the basic services, including sexual and reproductive health (SRH) needs. The aim of this study was to investigate the responses to the essential SRH needs for women during the COVID-19 pandemic. This narrative review was conducted based on the Scale for Assessing Narrative Review Articles (SANRA), in order to present key activities for responding to the important SRH needs of women in the current COVID-19 pandemic. The literature search was performed through English databases of Cochrane Library, PubMed, Scopus and ScienceDirect, as well as Persian databases including Magiran and Scientific Information Database (SID). In addition, the World Health Organization (WHO), the Joint United Nations Programme on HIV and AIDS (UNAIDS) and the reports of Center for Disease Control and Prevention (CDC) were searched. The search was carried out from December 2019 up to 10 January 2021. Essential reproductive healthcare services for women during the COVID-19 pandemic were divided into six categories including access to contraception, safe abortion and post-abortion care, sexual health and sexually transmitted disease (STD) prevention, cervical cancer screening and prevention, maternity services and also addressing violence against women and girls. These essential needs should be considered as a priority by governments as well as public and private stakeholders. It seems that the implementation of the shifted strategies, active participation of public and private stakeholders, consideration of human rights and ethical issues, ensuring access to vulnerable populations, regular contact with individuals and the increased cooperation of individuals for responding to the SRH needs during the COVID-19 outbreak, are necessary.
Will income inequality influence the abatement effect of renewable energy technological innovation on carbon dioxide emissions?

Environmental pollution and income inequality have become two salient issues in China. To achieve a green economic transformation, China urgently needs to develop renewable energy technologies to reduce carbon dioxide (CO2) emissions. However, the relationship among income inequality, renewable energy technological innovation (RETI) and CO2 emissions has not received sufficient attention in the current literature. Based on Chinese provincial panel data from 2000 to 2015, this paper adopts a panel fixed effect regression model and a panel threshold model to perform an analysis on the nonlinear relationship among these factors. The results show that (1) RETI is conducive to reducing per capita CO2 emissions (PCE). However, with an increase in income inequality, the abatement effect of RETI on per capita CO2 emissions will be hindered, and RETI will even positively contribute to PCE. (2) The panel threshold model shows that the impact of RETI on PCE has a significant single-threshold effect with regard to income inequality. When income inequality is lower than the threshold value, the impact of RETI on PCE is not significant. However, above the threshold value, that is, within the interval of higher income inequality, an increase in RETI will positively contribute to PCE. Finally, from the perspectives of income inequality and RETI, relevant policy implications are put forward for achieving the transformation of a low-carbon economy.
A systematic decision -making approach for planning and assessment of hybrid renewable energy -based microgrid with techno-economic optimization: A case study on an urban community in Egypt

This paper proposes a systematic and integrative decision-making approach for efficient planning and assessment of hybrid renewable energy-based microgrid (HRE-MG) systems. The approach is combined with an extensive techno-economic optimization analysis. The proposed methodology is validated with an actual case study on an urban city in Egypt, with the developed HRE-MG comprising solar, wind, diesel, and fuel cell energies. Different hybridization scenarios are modeled, evaluated and compared to obtain the most practicable solution with minimum cost and emission impact. The obtained results reveal that solar, wind, fuel cell show optimal configuration plan that yields a minimum net present and energy costs. Also, it achieves a significant reduction in carbon gases and increases system renewable fraction compared to other scenarios. Further, the reliability of the proposed hybrid energy system is examined under loss of power supply probability concept. A sensitivity analysis is then conducted to verify the model accuracy and examine the cost performance of the designed system concerning uncertain parameters.