ahmedabdelwahed/Medical_papers_title_and_abstract_NLP_dataset huggingface dataset:
Coordination of dual-function acquisition price and corporate social responsibility in a sustainable closed-loop supply chain

In reverse supply chains, acquisition price strategy provided by manufacturers plays an essential role in collecting used products. On the other hand, owing to the fact that the acquisition price contributes to the improvement of the environmental sustainability, it can influence the purchasing behaviors of eco-friendly customers. Thus, acquisition price strategy not only can positively affect the amount of returned products but also can positively affect the market demand. This study integrates bilateral effects of the acquisition price to analyze the performance of a sustainable closed-loop supply chain (CLSC) by introducing a dual-function acquisition price. This paper also contributes to the sustainable CLSC literature by proposing an analytical coordination mechanism to coordinate the dual-function acquisition price as an environmental sustainability and corporate social responsibility (CSR) as a social sustainability. Motivated by a real case of dairy industry, the bilateral effects of the acquisition price on both reverse and forward channels are considered through its dual functionality. In the sustainable CLSC consisting of two competitive manufacturers and one retailer, the manufacturers compete with each other on the dual-function acquisition price offered to the customers. Moreover, to facilitate the collection process, the manufacturers encourage the retailer to do the collection process by offering him a credit time scheme. Besides the collection process, the retailer invests in the CSR as social sustainability to boost the market share. At first, we use a manufacturer-Stackelberg game to model the problem under decentralized structure where each member individually optimizes its own profitability. Afterward, the problem is formulated under centralized structure where the decision variables are determined from CLSC viewpoint. Then, a compensation-based wholesale price contract is developed to coordinate the competitive CLSC under coordinated model. Using the data of the case study, the results demonstrate that the proposed contract enhances the whole CLSC and all members' profitability, the manufacturers' dual-function acquisition price, and the retailer's CSR investment. Therefore, the developed contract can improve the performance of the competitive CLSC from environmental, social, and economic viewpoints. (C) 2019 Elsevier Ltd. All rights reserved.
Evaluation of shape factor impact on discharge coefficient of side orifices using boost simulation model with extreme learning machine data-driven

In this paper, for the first time, the impact of the shape factor on the discharge coefficient of side orifices is evaluated using the novel Extreme Learning Machine (ELM) model. In addition, the Monte Carlo simulations (MCs) are applied to assess the accuracy of the modelling. Furthermore, the validation is conducted by means of the k-fold cross-validation approach (with k = 5). In other words, the most optimized number of hidden neurons is chosen to be equal to 30 and the results of all activation functions of the extreme learning machine are examined and the sigmoid activation function is selected for simulating the discharge coefficient. Subsequently, two modelling combinati0ons are introduced using the input parameters and five different extreme learning machine models are also developed. The analysis of the modelling results exhibits that the model with the shape factor is more accurate. The superior model is a function of all input parameters reasonably estimating the discharge coefficient. For example, the values of R and MAPE for this model are estimated to be 0.990 and 0.223, respectively. The results of the superior model are also compared with the empirical equations and it was shown that this model has higher accuracy.
Label-free identification of human glioma xenograft of mouse brain with quantitative ultraviolet photoacoustic histology imaging

The ability to unveil molecular specificities of endogenous nonfluorescent chromophores of ultraviolet photoacoustic imaging technology enables label-free histology imaging of tissue specimens. In this work, we exploit ultraviolet photoacoustic microscopy for identifying human glioma xenograft of mouse brain ex vivo. Intrinsically excellent imaging contrast of cell nucleus at ultraviolet photoacoustic illumination along with good spatial resolution allows for discerning the brain glioma of freshly-harvested thick brain slices, which circumvents laborious time-consuming preparations of the tissue specimens including micrometer-thick slicing and H&E staining that are prerequisites in standard histology analysis. The identification of tumor margins and quantitative analysis of tumor areas is implemented, representing good agreement with the standard H&E-stained observations. Quantitative ultraviolet photoacoustic microscopy can access fast pathological assessment to the brain tissues, and thus potentially facilitates intraoperative brain tumor resection to precisely remove all cancerous cells and preserve healthy tissue for maintaining its essential function.
Outstanding Multi-Photon Absorption at π-Delocalizable Metallodendrimers

Multi-photon absorption (MPA) has attracted interest for applications exploiting the tight spatial control of interaction volume and long wavelength excitation. However, a deficiency of molecules exhibiting higher-order nPA (n-photon absorption, n>2) and a lack of structure-property studies to define the key structural characteristics needed to optimize higher-order MPA performance have hindered practical development. We herein report the syntheses of second- and third-generation metallodendrimers and assessment of their nonlinear absorption, together with those of zero- and first-generation analogues. We report the first 5PA and 6PA data for an organometallic. The largest dendrimer exhibits exceptional three-, four-, five- and six-photon absorption to femtosecond-pulsed light. The systematically varied compounds highlight the crucial role of metal-to-oligo(phenyleneethynylene) charge transfer in promoting outstanding MPA activity.
Respondents' Involvement in Tourist Activities at the Time of the COVID-19 Pandemic

The article is aimed at presenting the survey respondents' involvement in tourist activities, taking into account certain factors at the time of the COVID-19 pandemic. The main objective may be divided into three direct aims, each of which consists of the determination of the factors that can influence the choice of tourist journeys: (1) organizational factors, (2) social-economic ones, and (3) sustainable development. The authors' own research findings are used to verify the objective. The research was conducted in April and May 2020 with the use of a diagnostic survey method and a questionnaire. Five-hundred sixty-four respondents from Poland (Podlaskie, Masovian, and Lesser Poland Voivodeships) and 133 respondents from the US (New York State, New Jersey, and Illinois) took part in the research. It was divided into organizational, social-economic, and sustainable development related factors. The research confirmed, inter alia, a great impact of the COVID-19 pandemic on the organization of tourist travels by the respondents in 2020. The issue presented in the article is a new one; it has not yet been a subject matter of research. That is the major reason the authors aimed to conduct it. What is a new methodological element in the article is the organization of some concepts concerning tourism and a presentation of the influence of COVID-19 on tourism. In the authors' opinion, the issues presented are new and have a considerable impact on new trends in the development of tourism at the time of the COVID-19 pandemic. The issue discussed is very broad, and the article does not exhaust it. The research findings are compared to the research findings reported by other authors, and standard deviations are calculated.
Antibacterial, anti-biofilm, and anti-virulence potential of tea tree oil against leaf blight pathogen Xanthomonas oryzae pv. oryzae instigates disease suppression

Bacterial leaf blight (BLB) disease, caused by Xanthomonas oryzae pv. oryzae (Xoo), causes major annual economic losses around the world. Inorganic copper compounds and antibiotics are conventionally used to control BLB disease. They often cause environmental pollution, contributing to adverse effects on human health. Therefore, research is now leading to the search for alternative control methods. Tea tree oil (TTO) is obtained from a traditional medicinal plant, Melaleuca alternifolia, with antibacterial properties. In this study, we found that TTO showed antibacterial activity against Xoo with a minimum inhibitory concentration (MIC) of 18 mg/ml. These antagonistic activities were not limited only to planktonic cells, as further studies have shown that TTO effectively eradicated sessile cells of Xoo in both initial and mature biofilms. Furthermore, it was also observed that TTO reduced various key virulence properties of Xoo, such as swimming, swarming motility, and the production of extracellular polymeric substances, xanthomonadin, and exoenzymes. TTO triggered ROS generation with cell membrane damage as an antibacterial mode of action against Xoo. The in silico study revealed that 1,8-cineole of TTO was effectively bound to two essential proteins, phosphoglucomutase and peptide deformylase, responsible for the synthesis of EPS and bacterial survival, respectively. These antibacterial and anti-virulence activities of TTO against Xoo were further confirmed by an ex vivo virulence assay where TTO significantly reduced the lesion length caused by Xoo on rice leaves. All these data concluded that TTO could be a safe, environment-friendly alternative approach for the comprehensive management of BLB disease.
Quantifying expansion and removal of Spartina alterniflora on Chongming island, China, using time series Landsat images during 1995-2018

The rampant encroachment of Spartina alterniflora into coastal wetlands of China over the past decades has adversely affected both coastal ecosystems and socio-economic systems. However, there are no annual or multi-year epoch maps of Spartina saltmarsh in China, which hinders our understanding and management of Spartina invasion. In this study, we selected Chongming island, China, where Spartina saltmarsh had expanded rapidly since its introduction in the 1990s. We investigated phenology of Spartina, Phragmites and Scirpus saltmarshes, and the time series vegetation indices derived from Landsat images showed that Spartina saltmarsh did not green-up in April-May and stayed green in December-January, which differed from the phenology of Phragmites and Scirpus saltmarshes. We developed a pixel- and phenology-based algorithm that used time series Landsat data to identify and map Spartina saltmarsh, and we applied it to quantify the temporal dynamics (expansion and removal) of Spartina saltmarsh on Chongming island during 1995-2018. The resultant maps showed that Spartina saltmarsh area on Chongming island increased from similar to 4 ha in 1995 to similar to 2067 ha in 2012 but dropped substantially to similar to 729 ha in 2016 after a large-scale ecological engineering project (US$ 186 million) was started to remove Spartina during 2013-2016. Chongming island still had similar to 1315 ha Spartina saltmarsh in 2018, and majority of it was distributed outside the Chongming Dongtan National Nature Reserve, which could serve as the sources for reinvasion in the near future. This study demonstrates the feasibility of using time series Landsat images, pixel- and phenology-based algorithm, and GEE platform to identify and map Spartina saltmarsh over years in the region, which is useful to the management of invasive plants in coastal wetlands.
Particulate matter-bound organic compounds: levels, mutagenicity, and health risks

Increased industrialization and consumption of fossil fuels in the Metropolitan Region of São Paulo (MRSP), Brazil, have caused a growth of the particulate matter emissions to the atmosphere and an increase in population health problems. Particulate and gaseous phase samples were collected in different short campaigns (2015, 2016, and 2017) near an urban-industrial area. Organic carbon (OC), elemental carbon (EC), polycyclic aromatic hydrocarbons (PAH), and its derivatives (nitro and oxy-PAH), n-alkanes, hopanes, and pesticides were determined. The Salmonella/microsome test confirmed the mutagenic activity of these samples. Among PAH, benzo(a)pyrene was detected as one of the most abundant compounds. Benzo(a)pyrene equivalent concentrations for PAH and nitro-PAH, and the associated risk of lung cancer, showed values above those recommended in the literature. The profile of n-alkanes confirmed the predominance of anthropogenic sources. Pesticide concentrations and estimated risks, such as the daily inhalation exposure and hazard quotient, suggest that exposure to these compounds in this area may be dangerous to human health.
Life cycle assessment of a small-scale methanol production system: A Power-to-Fuel strategy for biogas plants

Power-to-Fuel (PtF) systems use carbon dioxide and hydrogen as feedstock together for renewable fuel production and can hence contribute to climate change mitigation. This study assesses the environmental performance, from cradle to gate, of an innovative PtF system for synthetic methanol production, which integrates a biogas plant based on manure and straw residues as well as a combined heat and power unit. Under this concept, the residual carbon dioxide from biogas production is used for the synthesis of methanol, whereas hydrogen is obtained via wind-based electrolysis. A life cycle assessment (LCA) is carried out here for 1 kg of methanol produced with the integrated system proposed, operated on a small scale. In view of the multi-functionality of the process, the uncertainty in LCA outcomes is assessed by considering different assumptions on co-product credits for both the electricity from cogeneration and the digestate from the anaerobic digestion of organic raw materials. Additionally, a sensitivity analysis is performed to examine the influence of variability in life cycle inventory data on the results. All the analysed scenarios show significant improvements compared with conventional methanol production from fossil resources (with only a few exceptions for acidification and eutrophication). The sensitivity analysis shows that parameters determining the overall energy requirements as well as methane losses from anaerobic digestion in the PtF system greatly influence its environmental performance, and should be carefully considered in process design and upscaling. In spite of the uncertainty inherent in LCA, the system is presented as an interesting option to produce renewable methanol while contributing towards a circular economy, provided that the economic performance is also beneficial relative to the fossil alternative. (C) 2020 Elsevier Ltd. All rights reserved.
Change in cotton plant quality in response to application of anaerobically digested sewage sludge

Treated municipal sewage sludge (TSS) was applied to the cotton plant at rates of 10, 20 and 30 t/ha per year. Seed cotton yield (71.4%), lint yield (67.7%) and cottonseed yield (74.1%) were increased significantly when sludge was applied at a rate of 30 t/ha (TSS3). The effects of TSS applications on seed yield, lint yield and cottonseed yield were listed as TSS3 > TSS2 > CF > TSS1 > C according to the applications. The increasing TSS levels had a positive effect and increased the total N concentration compared to the control. The highest N value was observed in TSS3 plots, while the lowest value was recorded in control (C) plots. The highest P value was found in control (C) at 0.80% and in 10 t/ha (TSS1) at 0.80%, while the lowest value was found in the TSS2 application (0.70%). The K concentration of cottonseed increased with the increasing TSS rates, from 1.56% in control plots to 2.20% in 20 t/ha application (TSS2). Corresponding to the TSS levels, the calcium of plant tissues was determined by a range of 0.12-0.13%. The treatments of TSS and mineral fertilizer had similar effects on the Mg content of cottonseed, which was in the range of 0.38-0.43%. Na content in plant tissue increased with increasing dose of sludge application compared to control soils. Increasing doses of TSS had no significant effect on the concentrations of iron (Fe), copper (Cu), zinc (Zn), manganese (Mn) and boron (B) in cottonseed. The order of the elements with respect to their amounts in cottonseed was as follows: Fe > Zn > Na > B > Mn > Cu. The concentrations of non-essential elements (Ni, Cd, Cr, Pb, Hg and As) in cottonseed were below the permissible limits.
Provincial perspective analysis on the coordination between urbanization growth and resource environment carrying capacity (RECC) in China

China has been implementing huge scale of urbanization in the past several decades and this will continue in the coming future years. Whilst the urbanization growth has presented good benefits to social and economic development in China, it has also brought severe challenges to the resource environment carrying capacity, such as air pollution, overloaded land resources. These challenges present differently in different provinces, which leads to the disparity in development between provinces. There has been growing concern whether the urbanization growth in different provinces is coordinated with resource environment carrying capacity (RECC), but this question has not been addressed in previous studies. This paper presents a critical analysis on the coordination between urbanization growth and resources environment carrying capacity (RECC) from provincial perspective in the context of China. A measurement of coordination degree (CD) is used to measure whether and to what extent that urbanization growth and RECC are coordinated by applying coupling coordination degree model (CCDM). The research data are collected from 30 provinces in China. The results suggest that the average coordination performance among the provinces experienced a steady growth during the period of 2005-2016, but there still exists big room for improvement towards well balanced coordination performance. From provincial perspective, the good performers are mainly economically developed provinces. The findings provide valuable references for the governments at both central and local level to adopt proper policy measures where necessary to improvement the coordination performance between urbanization and RECC. (C) 2020 Elsevier B.V. All rights reserved.
BODIPY based Metal-Organic Macrocycles and Frameworks: Recent Therapeutic Developments

Boron dipyrromethene, commonly known as BODIPY, based metal-organic macrocycles (MOCs) and metal-organic frameworks (MOFs) represent an interesting part of materials due to their versatile tunability of structure and functionality as well as significant physicochemical properties, thus broadening their applications in various scientific domains, especially in biomedical sciences. With increasing concern over the efficacy of cancer drugs versus quality of patient's life dilemma, scientists have been trying to fabricate novel comprehensive therapeutic strategies along with the discovery of novel safer drugs where research with BODIPY metal complexes has shown vital advancements. In this review, we have exclusively examined the articles involving studies related to light harvesting and photophysical properties of BODIPY based MOCs and MOFs, synthesized through self-assembly process, with a special focus on biomolecular interaction and its importance in anti-cancer drug research. In the end, we also emphasized the possible practical challenges involved during the synthetic process, based on our experience on dealing with BODIPY molecules and steps to overcome them along with their future potentials. This review will significantly help our fellow research groups, especially the budding researchers, to quickly and comprehensively get the near to wholesome picture of BODIPY based MOCs and MOFs and their present status in anti-cancer drug discovery.
Sinonasal Hamartomas: From Nasal Chondromesenchymal Hamartoma to Respiratory Epithelial Adenomatoid Hamartoma. Report of six Cases and Review of the Literature

Sinonasal hamartomas are uncommon lesions of nasal and sinus cavities. Based on indigenous cellular components and characteristic histologic features, they are further classified into four entities: respiratory epithelial adenomatoid hamartoma (REAH), seromucinous hamartoma (SH), chondro-osseous and respiratory epithelial hamartoma (CORE), and nasal chondromesenchymal hamartoma (NCH). REAH, SH, and CORE are seen in adult patients, while NCH predominantly occurs in newborns and infants. Morphologically REAH and SH are composed of respiratory epithelium and seromucinous glands, CORE is related to REAH but with additional feature of chondroid and/or osseous tissue, and NCH is composed of chondroid and stromal elements but devoid of epithelial component. All four lesions can present as sinonasal mass lesions and with associated obstructive symptoms. Given the rarity of these lesions, diagnosis can be challenging, especially in unusual clinical scenario. In this study, we report six cases of sinonasal hamartoma, including one case of NCH, one case of CORE, two cases of SH, and two cases of REAH. All cases were from adult patients including four men and two women. We also review the literature of the clinical and pathologic features of these rare lesions.
Operation of conventional and unconventional energy sources to drive a reverse osmosis desalination plant in Sinai Peninsula, Egypt

Desalination process is an essential demand to overcome the lack of drinking water in remote areas in Egypt. Hybrid energy system drives desalination techniques to provide potable water for islands and coastal zones where there is no electrical grid. This paper analyzes the technical configuration, sizing and economic optimization of off-grid hybrid energy system powered reverse osmosis plant. The hybrid system consists of wind turbines, photovoltaic panels, converters, storage batteries, and a diesel generator. The objective of this study is to satisfy the electrical energy demand of the reverse osmosis (RO) plant with a freshwater capacity of 100 m(3)/day for use at Nakhl, North Sinai, Egypt. This simulation studied eleven different configurations of energy sources to select the optimal case at the proposed location. Homer package is used to select the cost-effective, sustainable and socially accepted system. The simulation is based on calculating the net present cost (NPC), excess system electricity, cost of energy (COE) and carbon dioxide emissions (CO2). Through the study, the optimal configuration consists of 160 kW photo-voltaic (PV) panels, 19 strings of lead-acid batteries and a 50 kW diesel generator system. The optimal case achieves the lowest cost of energy ($0.107/kWh) and net present cost ($502,662). (C) 2019 Elsevier Ltd. All rights reserved.
Investigating thyroid nodules

Thyroid nodules are common clinically and even more common as an incidental finding during ultrasonography. Routine screening of thyroid nodules in patients with hyperthyroidism or hypothyroidism without risk factors for thyroid cancer is not recommended. Most thyroid nodules are benign. Sonographic risk-stratification systems should be used to estimate the risk of malignancy and the need for fine-needle aspiration biopsy. Malignant thyroid nodules require surgical management. Most thyroid cancers are well-differentiated papillary or follicular thyroid neoplasms, which have an excellent prognosis with a low mortality rate.