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OBJECTIVE: To report 2 cases of serotonin syndrome with serious extrapyramidal movement disorders occurring when metoclopramide was coadministered with sertraline or venlafaxine.
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OBJECTIVE: To report 2 cases of serotonin syndrome with serious extrapyramidal movement disorders occurring when metoclopramide was coadministered with sertraline or venlafaxine.
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OBJECTIVE: To report 2 cases of serotonin syndrome with serious extrapyramidal movement disorders occurring when metoclopramide was coadministered with sertraline or venlafaxine.
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Serotonin syndrome caused by selective serotonin reuptake-inhibitors-metoclopramide interaction.
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She was administered metoclopramide because of nausea and, within 2 hours, developed agitation, dysarthria, diaphoresis, and a movement disorder.
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She was administered metoclopramide because of nausea and, within 2 hours, developed agitation, dysarthria, diaphoresis, and a movement disorder.
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She was administered metoclopramide because of nausea and, within 2 hours, developed agitation, dysarthria, diaphoresis, and a movement disorder.
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She was administered metoclopramide because of nausea and, within 2 hours, developed agitation, dysarthria, diaphoresis, and a movement disorder.
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She was admitted following a fall and, after being given metoclopramide, developed movement disorder and a period of unresponsiveness.
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She was admitted following a fall and, after being given metoclopramide, developed movement disorder and a period of unresponsiveness.
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A patient suffering from a rare enzyme deficiency developed a malignant neuroleptic syndrome after having been treated with one single dose of haloperidol.
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BACKGROUND: reports on delated cutaneous reactions to captopril have been seldom reported.
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Captopril is an angiotensin-converting enzyme (ACE) inhibitor and their cutaneous side-effects are documented, but little has been published concerning the usefulness of patch test when they occur.
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Dermatitis to captopril.
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We presented the case of a patient who developed a cutaneous reaction induced by captopril with positive patch test.
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A 62-year-old Caucasian man with atrial fibrillation who was taking warfarin reported an episode of hematochezia; his international normalized ratio (INR) was 1.74.
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Warfarin-associated bleeding complication saved life.
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Warfarin-associated bleeding generally is considered deleterious; however, in our patient it unmasked an early stage of colon cancer and thus may have saved the patient's life.
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A case of polymyositis with dilated cardiomyopathy associated with interferon alpha treatment for hepatitis B.
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A case of polymyositis with dilated cardiomyopathy associated with interferon alpha treatment for hepatitis B.
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In this case, interferon alpha induced polymyositis and cardiomyopathy is diagnosed in a 33-yr-old male patient with history of chronic hepatitis B.
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In this case, interferon alpha induced polymyositis and cardiomyopathy is diagnosed in a 33-yr-old male patient with history of chronic hepatitis B.
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Polymyositis is a rare complication of interferon alpha treatment as a result of immune-modulating role of the drug itself.
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To treat hepatitis B, interferon alpha was administered until the proximal muscle weakness developed.
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Long-term follow-up after neoplastic seeding complicating percutaneous ethanol injection for treatment of hepatocellular carcinoma.
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We describe a case of subcutaneous metastasis along the needle track after percutaneous ethanol injection (PEI) for treatment of hepatocellular carcinoma.
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Aggressive endometrial carcinoma in a breast cancer patient treated with tamoxifen with normal transvaginal ultrasonography.
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Since tamoxifen therapy can induce endometrial disorders, surveillance schemes of women taking tamoxifen have been recommended.
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Since tamoxifen therapy can induce endometrial disorders, surveillance schemes of women taking tamoxifen have been recommended.
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We described a very atypical case of a high stage, high grade endometrial cancer associated with tamoxifen in a 64-year-old woman with a past history of breast cancer.
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Beginning ductopenia was present in two, suggesting that itraconazole might be responsible for the occurrence of prolonged drug-induced cholangiopathy.
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Beginning ductopenia was present in two, suggesting that itraconazole might be responsible for the occurrence of prolonged drug-induced cholangiopathy.
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CONCLUSIONS: Itraconazole-induced liver injury presents with a cholestatic pattern of injury with damage to the interlobular bile ducts, possibly leading to ductopenia.
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CONCLUSIONS: Itraconazole-induced liver injury presents with a cholestatic pattern of injury with damage to the interlobular bile ducts, possibly leading to ductopenia.
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CONCLUSIONS: Itraconazole-induced liver injury presents with a cholestatic pattern of injury with damage to the interlobular bile ducts, possibly leading to ductopenia.
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CONCLUSIONS: Itraconazole-induced liver injury presents with a cholestatic pattern of injury with damage to the interlobular bile ducts, possibly leading to ductopenia.
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Hepatotoxicity related to itraconazole: report of three cases.
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METHODS: Three patients with apparent itraconazole-induced liver injury were studied.
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The occurrence of acute hepatitis is best known for ketoconazole.
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We report on three patients who developed acute liver damage during therapy with itraconazole, and in whom liver biopsy specimens were obtained.
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We suggest that itraconazole should be added to the list of drugs that may be responsible for a drug-induced vanishing bile duct syndrome.
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With itraconazole, hepatotoxic reactions have only very rarely been reported, and histologic data are lacking.
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Thrombotic stroke associated with the use of porcine factor VIII in a patient with acquired haemophilia.
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We have recently encountered a patient with acquired haemophilia who developed a thrombotic left middle cerebral artery distribution stroke while being treated with pFVIII.
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We speculate that platelet activation induced by pFVIII may have contributed to thrombosis and suggest that pFVIII be used with caution in elderly patients with pre-existing cardiovascular risk factors.
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Cutaneous sarcoidosis during interferon alfa and ribavirin treatment of hepatitis C virus infection: two cases.
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Cutaneous sarcoidosis during interferon alfa and ribavirin treatment of hepatitis C virus infection: two cases.
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There have been more than 20 observations of the appearance or aggravation of this granulomatosis with interferon alfa and more recently with the combination of interferon alfa plus ribavirin.
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There have been more than 20 observations of the appearance or aggravation of this granulomatosis with interferon alfa and more recently with the combination of interferon alfa plus ribavirin.
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There have been more than 20 observations of the appearance or aggravation of this granulomatosis with interferon alfa and more recently with the combination of interferon alfa plus ribavirin.
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We report two new cases of sarcoidosis in two patients with hepatitis C virus infection treated with interferon alfa and ribavirin.
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We report two new cases of sarcoidosis in two patients with hepatitis C virus infection treated with interferon alfa and ribavirin.
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CONCLUSIONS: Although mirtazapine offers clinicians a combination of strong efficacy and good safety, we suggest bearing SS in mind when prescribing this drug, especially in frail, elderly patients with underlying chronic conditions.
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DISCUSSION: A review of the cases of SS with implication of mirtazapine as the cause was performed.
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OBJECTIVE: To document a case of serotonin syndrome (SS) associated with mirtazapine monotherapy, review the previously reported cases of SS associated with this tetracyclic antidepressant, and discuss the possible pathogenic mechanisms leading to this serious adverse drug reaction.
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OBJECTIVE: To document a case of serotonin syndrome (SS) associated with mirtazapine monotherapy, review the previously reported cases of SS associated with this tetracyclic antidepressant, and discuss the possible pathogenic mechanisms leading to this serious adverse drug reaction.
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Severe serotonin syndrome induced by mirtazapine monotherapy.
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Pulmonary toxicity secondary to procarbazine.
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A 64-year-old man presented with proteinuria during postoperative interferon (IFN)-beta therapy against malignant melanoma.
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Minimal change nephrotic syndrome developing during postoperative interferon-beta therapy for malignant melanoma.
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To our knowledge this is the first report that demonstrates histological abnormalities of the glomerulus associated with postoperative IFN-beta therapy for the malignant melanoma.
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The authors report two cases of delayed elimination of methotrexate in patients receiving ciprofloxacin, with severe toxicity.
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The authors report two cases of delayed elimination of methotrexate in patients receiving ciprofloxacin, with severe toxicity.
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The authors report two cases of delayed elimination of methotrexate in patients receiving ciprofloxacin, with severe toxicity.
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CONCLUSIONS: Clinicians should be aware of the possible association of thrombocytopenia with lansoprazole and discontinue the drug if thrombocytopenia becomes apparent.
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DISCUSSION: After exclusion of other causes, the onset of thrombocytopenia after administration of lansoprazole, the resolution of the adverse reaction after discontinuation of the drug, and the fact that no other medicines were introduced during this time frame lead us to believe that this was most likely an idiosyncratic thrombocytopenic response to lansoprazole.
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DISCUSSION: After exclusion of other causes, the onset of thrombocytopenia after administration of lansoprazole, the resolution of the adverse reaction after discontinuation of the drug, and the fact that no other medicines were introduced during this time frame lead us to believe that this was most likely an idiosyncratic thrombocytopenic response to lansoprazole.
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He was started on oral lansoprazole 60 mg twice daily and, on hospital day 2, his platelet count decreased to 102 x 10(3)/mm(3); on hospital day 3, the platelet count was 36 x 10(3)/mm(3).
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Lansoprazole-induced thrombocytopenia.
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OBJECTIVE: To describe a case of thrombocytopenia associated with the administration of lansoprazole.
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To date, this is the first reported case of what appears to be isolated thrombocytopenia associated with lansoprazole.
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Life-threatening anaphylactoid reaction to amifostine used with concurrent chemoradiotherapy for nasopharyngeal cancer in a patient with dermatomyositis: a case report with literature review.
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The most common side effects associated with amifostine are nausea, vomiting, hypotension, hypocalcemia and allergic reactions.
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The most common side effects associated with amifostine are nausea, vomiting, hypotension, hypocalcemia and allergic reactions.
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The most common side effects associated with amifostine are nausea, vomiting, hypotension, hypocalcemia and allergic reactions.
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The most common side effects associated with amifostine are nausea, vomiting, hypotension, hypocalcemia and allergic reactions.
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The most common side effects associated with amifostine are nausea, vomiting, hypotension, hypocalcemia and allergic reactions.
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The patient suffered a life-threatening anaphylactoid reaction to amifostine.
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Agranulocytosis during clozapine therapy.
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Granulocytopenia and agranulocytosis are considered among the most dangerous adverse effects of clozapine.
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Granulocytopenia and agranulocytosis are considered among the most dangerous adverse effects of clozapine.
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The female patient received clozapine in a daily dose of 400 mg, which induced agranulocytosis after 2 months.
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The male patient was treated with 225-mg/day clozapine and the time to the diagnosis of agranulocytosis was 6 weeks.
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A 53-year-old man developed NMS without rigidity while taking olanzapine.
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Atypical neuroleptic malignant syndrome associated with olanzapine.
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CASE SUMMARY: We report the case of a 31-year-old patient hospitalized due to behavioral alterations and treated with oral zuclopenthixol, an antipsychotic from the thioxanthene family, who developed an acute, painful erection.
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CONCLUSIONS: Priapism is an uncommon but potentially serious adverse effect of zuclopenthixol that practitioners, as with many other antipsychotics, should be aware of.
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DISCUSSION: The occurrence of priapism in our patient was related to zuclopenthixol.
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OBJECTIVE: To present a single case of zuclopenthixol-induced priapism and a literature review.
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Priapism associated with zuclopenthixol.
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The capacity of zuclopenthixol to induce priapism is thought to be due to its antagonist activity on alpha-adrenergic receptors.
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After identification of the index patient, additional inquiry revealed that the patient's mother was hospitalized previously for overwhelming sepsis associated with metamizole use.
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Metamizole, a nonsteroidal antiinflammatory agent, is prohibited in the United States because of the risk of agranulocytosis but is widely used in Mexico and other countries.
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Erythropoietin is beneficial in mitomycin-induced hemolytic-uremic syndrome.
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We describe a patient who developed HUS after treatment with mitomycin C (total dose 144 mg/m2) due to a carcinoma of the ascending colon.
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Levofloxacin-induced toxic epidermal necrolysis in an elderly patient.
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To our knowledge, this case is the first published report of levofloxacin-induced TEN.
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A 31-year-old female developed multiple episodes of grand mal seizures after combination chemotherapy with cisplatin, vinblastine and bleomycin for germ cell ovarian cancer stage Ic.
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A 31-year-old female developed multiple episodes of grand mal seizures after combination chemotherapy with cisplatin, vinblastine and bleomycin for germ cell ovarian cancer stage Ic.
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A 31-year-old female developed multiple episodes of grand mal seizures after combination chemotherapy with cisplatin, vinblastine and bleomycin for germ cell ovarian cancer stage Ic.
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