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<s>[INST]What is the clinical significance of RS1593412272 SNP, is it benign or pathogenic?[/INST] It is Uncertain significance.</s> |
<s>[INST]How long is the variation length for RS1593412272 SNP?[/INST] The variation length is 1 base pairs.</s> |
<s>[INST]What is the origin for RS1593412272 SNP?[/INST] The origin is germline.</s> |
<s>[INST]What is the type of genetic variation for RS1593412272 SNP?[/INST] The variation is a single nucleotide variant.</s> |
<s>[INST]What is the genetic molecular consequence for RS1593412272 SNP?[/INST] The resulting gene consequence is a missense variant.</s> |
<s>[INST]Which condition is asociated with RS1593532101 SNP?[/INST] Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS1593532101 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS1593532101 SNP.</s> |
<s>[INST]In which chromosome is RS1593532101 SNP located?[/INST] It is located in the chromosome 13.</s> |
<s>[INST]Which methods support the evidence found for the RS1593532101 SNP?[/INST] Associated methods are: clinical testing.</s> |
<s>[INST]What is the clinical significance of RS1593532101 SNP, is it benign or pathogenic?[/INST] It is Pathogenic.</s> |
<s>[INST]How long is the variation length for RS1593532101 SNP?[/INST] The variation length is 1 base pairs.</s> |
<s>[INST]What is the origin for RS1593532101 SNP?[/INST] The origin is germline.</s> |
<s>[INST]What is the type of genetic variation for RS1593532101 SNP?[/INST] The variation is a Insertion.</s> |
<s>[INST]What is the genetic molecular consequence for RS1593532101 SNP?[/INST] The resulting gene consequence is a splice donor variant.</s> |
<s>[INST]Which condition is asociated with DEL652514?[/INST] Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsDEL652514. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/DEL652514.</s> |
<s>[INST]In which chromosome is DEL652514 located?[/INST] It is located in the chromosome 13.</s> |
<s>[INST]Which methods support the evidence found for the DEL652514?[/INST] Associated methods are: clinical testing.</s> |
<s>[INST]What is the clinical significance of DEL652514, is it benign or pathogenic?[/INST] It is Pathogenic.</s> |
<s>[INST]How long is the variation length for DEL652514?[/INST] The variation length is 3514 base pairs.</s> |
<s>[INST]What is the origin for DEL652514?[/INST] The origin is germline.</s> |
<s>[INST]What is the type of genetic variation for DEL652514?[/INST] The variation is a Deletion.</s> |
<s>[INST]Which condition is asociated with RS1593539538 SNP?[/INST] Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS1593539538 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS1593539538 SNP.</s> |
<s>[INST]In which chromosome is RS1593539538 SNP located?[/INST] It is located in the chromosome 13.</s> |
<s>[INST]Which methods support the evidence found for the RS1593539538 SNP?[/INST] Associated methods are: clinical testing.</s> |
<s>[INST]What is the clinical significance of RS1593539538 SNP, is it benign or pathogenic?[/INST] It is Pathogenic.</s> |
<s>[INST]How long is the variation length for RS1593539538 SNP?[/INST] The variation length is 1 base pairs.</s> |
<s>[INST]What is the origin for RS1593539538 SNP?[/INST] The origin is germline.</s> |
<s>[INST]What is the type of genetic variation for RS1593539538 SNP?[/INST] The variation is a Duplication.</s> |
<s>[INST]What is the genetic molecular consequence for RS1593539538 SNP?[/INST] The resulting gene consequence is a frameshift variant.</s> |
<s>[INST]Which condition is asociated with RS1593457138 SNP?[/INST] Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS1593457138 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS1593457138 SNP.</s> |
<s>[INST]In which chromosome is RS1593457138 SNP located?[/INST] It is located in the chromosome 13.</s> |
<s>[INST]Which methods support the evidence found for the RS1593457138 SNP?[/INST] Associated methods are: clinical testing.</s> |
<s>[INST]What is the clinical significance of RS1593457138 SNP, is it benign or pathogenic?[/INST] It is Uncertain significance.</s> |
<s>[INST]How long is the variation length for RS1593457138 SNP?[/INST] The variation length is 1 base pairs.</s> |
<s>[INST]What is the origin for RS1593457138 SNP?[/INST] The origin is germline.</s> |
<s>[INST]What is the type of genetic variation for RS1593457138 SNP?[/INST] The variation is a single nucleotide variant.</s> |
<s>[INST]What is the genetic molecular consequence for RS1593457138 SNP?[/INST] The resulting gene consequence is a missense variant.</s> |
<s>[INST]Which condition is asociated with RS1593529861 SNP?[/INST] Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS1593529861 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS1593529861 SNP.</s> |
<s>[INST]In which chromosome is RS1593529861 SNP located?[/INST] It is located in the chromosome 13.</s> |
<s>[INST]Which methods support the evidence found for the RS1593529861 SNP?[/INST] Associated methods are: clinical testing.</s> |
<s>[INST]What is the clinical significance of RS1593529861 SNP, is it benign or pathogenic?[/INST] It is Uncertain significance.</s> |
<s>[INST]How long is the variation length for RS1593529861 SNP?[/INST] The variation length is 1 base pairs.</s> |
<s>[INST]What is the origin for RS1593529861 SNP?[/INST] The origin is germline.</s> |
<s>[INST]What is the type of genetic variation for RS1593529861 SNP?[/INST] The variation is a single nucleotide variant.</s> |
<s>[INST]What is the genetic molecular consequence for RS1593529861 SNP?[/INST] The resulting gene consequence is a intron variant.</s> |
<s>[INST]Which condition is asociated with DEL652281?[/INST] Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsDEL652281. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/DEL652281.</s> |
<s>[INST]In which chromosome is DEL652281 located?[/INST] It is located in the chromosome 13.</s> |
<s>[INST]Which methods support the evidence found for the DEL652281?[/INST] Associated methods are: clinical testing.</s> |
<s>[INST]What is the clinical significance of DEL652281, is it benign or pathogenic?[/INST] It is Pathogenic.</s> |
<s>[INST]How long is the variation length for DEL652281?[/INST] The variation length is 41764 base pairs.</s> |
<s>[INST]What is the origin for DEL652281?[/INST] The origin is germline.</s> |
<s>[INST]What is the type of genetic variation for DEL652281?[/INST] The variation is a Deletion.</s> |
<s>[INST]Which condition is asociated with RS1593434175 SNP?[/INST] Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS1593434175 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS1593434175 SNP.</s> |
<s>[INST]In which chromosome is RS1593434175 SNP located?[/INST] It is located in the chromosome 13.</s> |
<s>[INST]Which methods support the evidence found for the RS1593434175 SNP?[/INST] Associated methods are: clinical testing.</s> |
<s>[INST]What is the clinical significance of RS1593434175 SNP, is it benign or pathogenic?[/INST] It is Pathogenic.</s> |
<s>[INST]How long is the variation length for RS1593434175 SNP?[/INST] The variation length is 5 base pairs.</s> |
<s>[INST]What is the origin for RS1593434175 SNP?[/INST] The origin is germline.</s> |
<s>[INST]What is the type of genetic variation for RS1593434175 SNP?[/INST] The variation is a Deletion.</s> |
<s>[INST]What is the genetic molecular consequence for RS1593434175 SNP?[/INST] The resulting gene consequence is a frameshift variant.</s> |
<s>[INST]Which condition is asociated with RS1593448511 SNP?[/INST] Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS1593448511 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS1593448511 SNP.</s> |
<s>[INST]In which chromosome is RS1593448511 SNP located?[/INST] It is located in the chromosome 13.</s> |
<s>[INST]Which methods support the evidence found for the RS1593448511 SNP?[/INST] Associated methods are: clinical testing.</s> |
<s>[INST]What is the clinical significance of RS1593448511 SNP, is it benign or pathogenic?[/INST] It is Uncertain significance.</s> |
<s>[INST]How long is the variation length for RS1593448511 SNP?[/INST] The variation length is 1 base pairs.</s> |
<s>[INST]What is the origin for RS1593448511 SNP?[/INST] The origin is germline.</s> |
<s>[INST]What is the type of genetic variation for RS1593448511 SNP?[/INST] The variation is a single nucleotide variant.</s> |
<s>[INST]What is the genetic molecular consequence for RS1593448511 SNP?[/INST] The resulting gene consequence is a intron variant.</s> |
<s>[INST]Which condition is asociated with RS1593454115 SNP?[/INST] Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS1593454115 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS1593454115 SNP.</s> |
<s>[INST]In which chromosome is RS1593454115 SNP located?[/INST] It is located in the chromosome 13.</s> |
<s>[INST]Which methods support the evidence found for the RS1593454115 SNP?[/INST] Associated methods are: clinical testing.</s> |
<s>[INST]What is the clinical significance of RS1593454115 SNP, is it benign or pathogenic?[/INST] It is Pathogenic.</s> |
<s>[INST]How long is the variation length for RS1593454115 SNP?[/INST] The variation length is 2 base pairs.</s> |
<s>[INST]What is the origin for RS1593454115 SNP?[/INST] The origin is germline.</s> |
<s>[INST]What is the type of genetic variation for RS1593454115 SNP?[/INST] The variation is a Duplication.</s> |
<s>[INST]What is the genetic molecular consequence for RS1593454115 SNP?[/INST] The resulting gene consequence is a frameshift variant.</s> |
<s>[INST]Which condition is asociated with RS1593411974 SNP?[/INST] Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS1593411974 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS1593411974 SNP.</s> |
<s>[INST]In which chromosome is RS1593411974 SNP located?[/INST] It is located in the chromosome 13.</s> |
<s>[INST]Which methods support the evidence found for the RS1593411974 SNP?[/INST] Associated methods are: clinical testing.</s> |
<s>[INST]What is the clinical significance of RS1593411974 SNP, is it benign or pathogenic?[/INST] It is Likely pathogenic.</s> |
<s>[INST]How long is the variation length for RS1593411974 SNP?[/INST] The variation length is 32 base pairs.</s> |
<s>[INST]What is the origin for RS1593411974 SNP?[/INST] The origin is unknown.</s> |
<s>[INST]What is the type of genetic variation for RS1593411974 SNP?[/INST] The variation is a Deletion.</s> |
<s>[INST]What is the genetic molecular consequence for RS1593411974 SNP?[/INST] The resulting gene consequence is a frameshift variant.</s> |
<s>[INST]Which condition is asociated with RS1312883856 SNP?[/INST] Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS1312883856 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS1312883856 SNP.</s> |
<s>[INST]In which chromosome is RS1312883856 SNP located?[/INST] It is located in the chromosome 13.</s> |
<s>[INST]Which methods support the evidence found for the RS1312883856 SNP?[/INST] Associated methods are: clinical testing.</s> |
<s>[INST]What is the clinical significance of RS1312883856 SNP, is it benign or pathogenic?[/INST] It is Uncertain significance.</s> |
<s>[INST]How long is the variation length for RS1312883856 SNP?[/INST] The variation length is 1 base pairs.</s> |
<s>[INST]What is the origin for RS1312883856 SNP?[/INST] The origin is unknown.</s> |
<s>[INST]What is the type of genetic variation for RS1312883856 SNP?[/INST] The variation is a single nucleotide variant.</s> |
<s>[INST]What is the genetic molecular consequence for RS1312883856 SNP?[/INST] The resulting gene consequence is a missense variant.</s> |
<s>[INST]Which condition is asociated with RS1593443469 SNP?[/INST] Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS1593443469 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS1593443469 SNP.</s> |
<s>[INST]In which chromosome is RS1593443469 SNP located?[/INST] It is located in the chromosome 13.</s> |
<s>[INST]Which methods support the evidence found for the RS1593443469 SNP?[/INST] Associated methods are: clinical testing.</s> |
<s>[INST]What is the clinical significance of RS1593443469 SNP, is it benign or pathogenic?[/INST] It is Uncertain significance.</s> |
<s>[INST]How long is the variation length for RS1593443469 SNP?[/INST] The variation length is 6 base pairs.</s> |
<s>[INST]What is the origin for RS1593443469 SNP?[/INST] The origin is unknown.</s> |
<s>[INST]What is the type of genetic variation for RS1593443469 SNP?[/INST] The variation is a Insertion.</s> |
<s>[INST]What is the genetic molecular consequence for RS1593443469 SNP?[/INST] The resulting gene consequence is a inframe_indel.</s> |
<s>[INST]Which condition is asociated with RS1593443514 SNP?[/INST] Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS1593443514 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS1593443514 SNP.</s> |