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<s>[INST]How long is the variation length for RS587778826 SNP?[/INST] The variation length is 1 base pairs.</s> |
<s>[INST]What is the origin for RS587778826 SNP?[/INST] The origin is somatic.</s> |
<s>[INST]What is the type of genetic variation for RS587778826 SNP?[/INST] The variation is a single nucleotide variant.</s> |
<s>[INST]What is the genetic molecular consequence for RS587778826 SNP?[/INST] The resulting gene consequence is a nonsense.</s> |
<s>[INST]Which condition is asociated with 132325?[/INST] Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/Rs132325. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/132325.</s> |
<s>[INST]In which chromosome is 132325 located?[/INST] It is located in the chromosome 13.</s> |
<s>[INST]Which methods support the evidence found for the 132325?[/INST] Associated methods are: research.</s> |
<s>[INST]What is the clinical significance of 132325, is it benign or pathogenic?[/INST] It is Pathogenic.</s> |
<s>[INST]How long is the variation length for 132325?[/INST] The variation length is None base pairs.</s> |
<s>[INST]What is the origin for 132325?[/INST] The origin is somatic.</s> |
<s>[INST]What is the type of genetic variation for 132325?[/INST] The variation is a Variation.</s> |
<s>[INST]Which condition is asociated with RS587778843 SNP?[/INST] Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS587778843 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS587778843 SNP.</s> |
<s>[INST]In which chromosome is RS587778843 SNP located?[/INST] It is located in the chromosome 13.</s> |
<s>[INST]Which methods support the evidence found for the RS587778843 SNP?[/INST] Associated methods are: clinical testing.</s> |
<s>[INST]What is the clinical significance of RS587778843 SNP, is it benign or pathogenic?[/INST] It is Pathogenic.</s> |
<s>[INST]How long is the variation length for RS587778843 SNP?[/INST] The variation length is 1 base pairs.</s> |
<s>[INST]What is the origin for RS587778843 SNP?[/INST] The origin is somatic.</s> |
<s>[INST]What is the type of genetic variation for RS587778843 SNP?[/INST] The variation is a single nucleotide variant.</s> |
<s>[INST]What is the genetic molecular consequence for RS587778843 SNP?[/INST] The resulting gene consequence is a nonsense.</s> |
<s>[INST]Which condition is asociated with RS587778855 SNP?[/INST] Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS587778855 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS587778855 SNP.</s> |
<s>[INST]In which chromosome is RS587778855 SNP located?[/INST] It is located in the chromosome 13.</s> |
<s>[INST]Which methods support the evidence found for the RS587778855 SNP?[/INST] Associated methods are: research.</s> |
<s>[INST]What is the clinical significance of RS587778855 SNP, is it benign or pathogenic?[/INST] It is Pathogenic.</s> |
<s>[INST]How long is the variation length for RS587778855 SNP?[/INST] The variation length is 1 base pairs.</s> |
<s>[INST]What is the origin for RS587778855 SNP?[/INST] The origin is germline.</s> |
<s>[INST]What is the type of genetic variation for RS587778855 SNP?[/INST] The variation is a single nucleotide variant.</s> |
<s>[INST]What is the genetic molecular consequence for RS587778855 SNP?[/INST] The resulting gene consequence is a nonsense.</s> |
<s>[INST]Which condition is asociated with RS587778856 SNP?[/INST] Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS587778856 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS587778856 SNP.</s> |
<s>[INST]In which chromosome is RS587778856 SNP located?[/INST] It is located in the chromosome 13.</s> |
<s>[INST]Which methods support the evidence found for the RS587778856 SNP?[/INST] Associated methods are: clinical testing.</s> |
<s>[INST]What is the clinical significance of RS587778856 SNP, is it benign or pathogenic?[/INST] It is Uncertain significance.</s> |
<s>[INST]How long is the variation length for RS587778856 SNP?[/INST] The variation length is 1 base pairs.</s> |
<s>[INST]What is the origin for RS587778856 SNP?[/INST] The origin is somatic.</s> |
<s>[INST]What is the type of genetic variation for RS587778856 SNP?[/INST] The variation is a single nucleotide variant.</s> |
<s>[INST]What is the genetic molecular consequence for RS587778856 SNP?[/INST] The resulting gene consequence is a synonymous variant.</s> |
<s>[INST]Which condition is asociated with RS587778845 SNP?[/INST] Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS587778845 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS587778845 SNP.</s> |
<s>[INST]In which chromosome is RS587778845 SNP located?[/INST] It is located in the chromosome 13.</s> |
<s>[INST]Which methods support the evidence found for the RS587778845 SNP?[/INST] Associated methods are: research.</s> |
<s>[INST]What is the clinical significance of RS587778845 SNP, is it benign or pathogenic?[/INST] It is Pathogenic.</s> |
<s>[INST]How long is the variation length for RS587778845 SNP?[/INST] The variation length is 1 base pairs.</s> |
<s>[INST]What is the origin for RS587778845 SNP?[/INST] The origin is somatic.</s> |
<s>[INST]What is the type of genetic variation for RS587778845 SNP?[/INST] The variation is a single nucleotide variant.</s> |
<s>[INST]What is the genetic molecular consequence for RS587778845 SNP?[/INST] The resulting gene consequence is a nonsense.</s> |
<s>[INST]Which condition is asociated with RS587778847 SNP?[/INST] Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS587778847 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS587778847 SNP.</s> |
<s>[INST]In which chromosome is RS587778847 SNP located?[/INST] It is located in the chromosome 13.</s> |
<s>[INST]Which methods support the evidence found for the RS587778847 SNP?[/INST] Associated methods are: research.</s> |
<s>[INST]What is the clinical significance of RS587778847 SNP, is it benign or pathogenic?[/INST] It is Pathogenic.</s> |
<s>[INST]How long is the variation length for RS587778847 SNP?[/INST] The variation length is 1 base pairs.</s> |
<s>[INST]What is the origin for RS587778847 SNP?[/INST] The origin is somatic.</s> |
<s>[INST]What is the type of genetic variation for RS587778847 SNP?[/INST] The variation is a single nucleotide variant.</s> |
<s>[INST]What is the genetic molecular consequence for RS587778847 SNP?[/INST] The resulting gene consequence is a missense variant.</s> |
<s>[INST]Which condition is asociated with RS587778863 SNP?[/INST] Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS587778863 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS587778863 SNP.</s> |
<s>[INST]In which chromosome is RS587778863 SNP located?[/INST] It is located in the chromosome 13.</s> |
<s>[INST]Which methods support the evidence found for the RS587778863 SNP?[/INST] Associated methods are: research.</s> |
<s>[INST]What is the clinical significance of RS587778863 SNP, is it benign or pathogenic?[/INST] It is Pathogenic.</s> |
<s>[INST]How long is the variation length for RS587778863 SNP?[/INST] The variation length is 1 base pairs.</s> |
<s>[INST]What is the origin for RS587778863 SNP?[/INST] The origin is somatic.</s> |
<s>[INST]What is the type of genetic variation for RS587778863 SNP?[/INST] The variation is a single nucleotide variant.</s> |
<s>[INST]What is the genetic molecular consequence for RS587778863 SNP?[/INST] The resulting gene consequence is a nonsense.</s> |
<s>[INST]Which condition is asociated with RS587781256 SNP?[/INST] Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS587781256 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS587781256 SNP.</s> |
<s>[INST]In which chromosome is RS587781256 SNP located?[/INST] It is located in the chromosome 13.</s> |
<s>[INST]Which methods support the evidence found for the RS587781256 SNP?[/INST] Associated methods are: clinical testing.</s> |
<s>[INST]What is the clinical significance of RS587781256 SNP, is it benign or pathogenic?[/INST] It is Pathogenic.</s> |
<s>[INST]How long is the variation length for RS587781256 SNP?[/INST] The variation length is 21 base pairs.</s> |
<s>[INST]What is the origin for RS587781256 SNP?[/INST] The origin is germline.</s> |
<s>[INST]What is the type of genetic variation for RS587781256 SNP?[/INST] The variation is a Deletion.</s> |
<s>[INST]What is the genetic molecular consequence for RS587781256 SNP?[/INST] The resulting gene consequence is a intron variant.</s> |
<s>[INST]Which condition is asociated with RS587781257 SNP?[/INST] Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS587781257 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS587781257 SNP.</s> |
<s>[INST]In which chromosome is RS587781257 SNP located?[/INST] It is located in the chromosome 13.</s> |
<s>[INST]Which methods support the evidence found for the RS587781257 SNP?[/INST] Associated methods are: clinical testing.</s> |
<s>[INST]What is the clinical significance of RS587781257 SNP, is it benign or pathogenic?[/INST] It is Pathogenic.</s> |
<s>[INST]How long is the variation length for RS587781257 SNP?[/INST] The variation length is 1 base pairs.</s> |
<s>[INST]What is the origin for RS587781257 SNP?[/INST] The origin is germline.</s> |
<s>[INST]What is the type of genetic variation for RS587781257 SNP?[/INST] The variation is a Deletion.</s> |
<s>[INST]What is the genetic molecular consequence for RS587781257 SNP?[/INST] The resulting gene consequence is a frameshift variant.</s> |
<s>[INST]Which condition is asociated with DEL399102?[/INST] Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsDEL399102. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/DEL399102.</s> |
<s>[INST]In which chromosome is DEL399102 located?[/INST] It is located in the chromosome 13.</s> |
<s>[INST]Which methods support the evidence found for the DEL399102?[/INST] Associated methods are: clinical testing.</s> |
<s>[INST]What is the clinical significance of DEL399102, is it benign or pathogenic?[/INST] It is Pathogenic.</s> |
<s>[INST]How long is the variation length for DEL399102?[/INST] The variation length is 2601 base pairs.</s> |
<s>[INST]What is the origin for DEL399102?[/INST] The origin is germline.</s> |
<s>[INST]What is the type of genetic variation for DEL399102?[/INST] The variation is a Deletion.</s> |
<s>[INST]Which condition is asociated with DEL399611?[/INST] Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsDEL399611. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/DEL399611.</s> |
<s>[INST]In which chromosome is DEL399611 located?[/INST] It is located in the chromosome 13.</s> |
<s>[INST]Which methods support the evidence found for the DEL399611?[/INST] Associated methods are: clinical testing.</s> |
<s>[INST]What is the clinical significance of DEL399611, is it benign or pathogenic?[/INST] It is Likely pathogenic.</s> |
<s>[INST]How long is the variation length for DEL399611?[/INST] The variation length is 1850 base pairs.</s> |
<s>[INST]What is the origin for DEL399611?[/INST] The origin is germline.</s> |
<s>[INST]What is the type of genetic variation for DEL399611?[/INST] The variation is a Deletion.</s> |
<s>[INST]Which condition is asociated with DEL463437?[/INST] Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsDEL463437. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/DEL463437.</s> |
<s>[INST]In which chromosome is DEL463437 located?[/INST] It is located in the chromosome 13.</s> |
<s>[INST]Which methods support the evidence found for the DEL463437?[/INST] Associated methods are: clinical testing.</s> |
<s>[INST]What is the clinical significance of DEL463437, is it benign or pathogenic?[/INST] It is Pathogenic.</s> |
<s>[INST]How long is the variation length for DEL463437?[/INST] The variation length is 41756 base pairs.</s> |
<s>[INST]What is the origin for DEL463437?[/INST] The origin is germline.</s> |
<s>[INST]What is the type of genetic variation for DEL463437?[/INST] The variation is a Deletion.</s> |
<s>[INST]Which condition is asociated with RS1555282775 SNP?[/INST] Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS1555282775 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS1555282775 SNP.</s> |
<s>[INST]In which chromosome is RS1555282775 SNP located?[/INST] It is located in the chromosome 13.</s> |
<s>[INST]Which methods support the evidence found for the RS1555282775 SNP?[/INST] Associated methods are: clinical testing.</s> |
<s>[INST]What is the clinical significance of RS1555282775 SNP, is it benign or pathogenic?[/INST] It is Pathogenic.</s> |