abdelmo/pubmed-dataset · Datasets at Hugging Face

A subfamily of G protein-coupled cellular receptors for lysophospholipids and lysosphingolipids.

er encompasses Edg-1; Edg-3 and Edg-5. Edg-3 and Edg-5 encode GPCRs specific for S1P; but not LPA. Preliminary data suggest that Edg-1 encodes a GPCR for S1P and one or more other lysosphingolipids; but the signals evoked by S1P alone are far weaker than those transduced by Edg-3 and Edg-5. Similarities of the structures of genes for the respective homology clusters supports this tentative classification of the Edg protein GPCRs. Future research will be directed to completion of the elucidation of genomic o

10667339

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A subfamily of G protein-coupled cellular receptors for lysophospholipids and lysosphingolipids.

rganization and signaling pathways; and a greater understanding of the breadth of functional roles of Edg proteins in development and activities of the nervous; cardiovascular; endocrine and immune systems.

10667339

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Evidence for involvement of prostaglandin I2 as a major nociceptive mediator in acetic acid-induced writhing reaction: a study using IP-receptor disrupted mice.

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Local anesthetic effects on TXA2 receptor mediated platelet aggregation using quenched flow aggregometry.

nan

10667341

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Volatile and local anesthetics interfere with thromboxane A2 receptors recombinantly expressed in Xenopus oocytes.

nan

10667342

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Aspirin-triggered 15-epi-lipoxin A4 and novel lipoxin B4 stable analogs inhibit neutrophil-mediated changes in vascular permeability.

nan

10667343

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Cleavage of leukotriene D4 in mice with targeted disruption of a membrane-bound dipeptidase gene.

nan

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Gamma-glutamyl leukotrienase cleavage of leukotriene C4.

nan

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LTE4 blood levels in infants with congenital heart lesions.

nan

10667346

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Evaluation of the pharmacological activity of the pure cysteinyl-leukotriene receptor antagonists CGP 45715A (iralukast) and CGP 57698 in human airways.

nan

10667347

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Evidence for a carbocation intermediate in the enzymatic transformation of leukotriene A4 into leukotriene B4.

nan

10667348

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A random rapid equilibrium mechanism for leukotriene C4 synthase.

Kinetic studies performed on the conjugation reaction catalyzed by LTC4 synthase proved to conform to a random rapid equilibrium mechanism which was further substantiated by competition patterns ruling out other possible mechanisms. Most cytosolic Gst's investigated to date appear to follow a random kinetic mechanism although are mainly responsible for detoxification purposes. Conversely; LTC4 synthase possesses a very different biological role yet still follows a similar mechanism. Therefore; it can be con

10667349

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A random rapid equilibrium mechanism for leukotriene C4 synthase.

cluded that most GSTs function in a consistent manner regardless of their biological function. Of interest are the mechanisms of the other members of the MAPEG family which in some respects are closer to conventional GSTs than to LTC4 synthase; yet they remain to be deciphered.

10667349

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Formation of reactive products of the isoprostane pathway: isolevuglandins and cyclopentenone isoprostanes.

nan

10667350

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Formation of novel isoprostane-like compounds from docosahexaenoic acid.

nan

10667351

[ null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null ]

cDNA cloning, expression and chromosomal localization of two human lysophosphatidic acid acyltransferases.

In this report we describe a pair of human LPAAT isozymes. These isozymes are encoded by distinct genes located on different chromosomes; but share sequence homology; substrate specificity; and intracellular location. The biological value of maintaining the two closely related LPAAT genes in the human genome is not clear. We find that both isozymes are widely expressed; although expression levels do diverge significantly in tissues such as the liver; placenta; testes; and pancreas. We also find that; at lea

10667352

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cDNA cloning, expression and chromosomal localization of two human lysophosphatidic acid acyltransferases.

st in the artificial system of over-expression in COS7 cells; both isozymes localize to the ER membrane. Thus; distinct tissue-specific or subcellular compartment-specific roles for the two isozymes are not supported by the current experimental evidence. It does remain possible that induction of expression or subcellular translocation of one or the other isozyme may distinguish their functions. A survey of a limited number of acyl CoA substrates indicates that the two isozymes display similar substrate spec

10667352

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cDNA cloning, expression and chromosomal localization of two human lysophosphatidic acid acyltransferases.

ificities; although slight differences are suggested by the data. However; extensive analysis of both isozymes with multiple substrates in the same assay system will be required to detect physiologically relevant differences in substrate specificity. LPA and PA are central intermediates in phospholipid biogenesis. Furthermore; they have the capacity to mediate signaling both between and within cells. The importance of these mediators is reflected in the growing body of literature dedicated to unraveling the

10667352

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cDNA cloning, expression and chromosomal localization of two human lysophosphatidic acid acyltransferases.

mechanistic basis for their actions. Until recently; the field has been hampered by a dearth of reagents appropriate for the molecular dissection of the LPA and PA metabolic and signaling pathways in eukaryotes. However; the recent cloning of possible LPA receptors will promote further understanding of LPA signaling. Similarly; the recent appearance of LPAAT homologs in the EST database has prompted a flurry of reports describing their characterization. These clones will afford opportunity for defining the

10667352

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cDNA cloning, expression and chromosomal localization of two human lysophosphatidic acid acyltransferases.

function of LPAAT in eukaryotic phospholipid metabolism.

10667352

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The first cloned and identified lysophospholipid (LP) receptor gene, vzg-1: implications for related receptors and the nervous system.

nan

10667353

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Involvement of protein kinase C, p38 MAP kinase and ERK in arachidonic acid-stimulated superoxide production in human neutrophils.

nan

10667354

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13(S)-HpODE augments epidermal growth factor signal transduction by attenuating EGF receptor dephosphorylation.

nan

10667355

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Role of lipoxygenase in the regulation of glucose transport in aortic vascular cells.

nan

10667356

[ null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null ]

Functions of the p21-activated protein kinases (Paks) in neutrophils and their regulation by complex lipids.

nan

10667357

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Inhibition of neurofibromin and p120 GTPase activating protein (GAP) by dietary fatty acids.

Neurofibromin and p120 GTPase activating protein (p120 GAP) down-regulate the activity of cellular Ras proteins. How the activity of these two proteins is controlled is not yet clear. In this study; we analyzed the effects of eight nutritionally relevant fatty acids on GTPase stimulatory activity of full-length neurofibromin and p120 GAP. The fatty acids tested were: saturated stearic acid; monounsaturated oleic acid; three omega-6 and three omega-3 polyunsaturated fatty acids. The analysis was performed by

10667358

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Inhibition of neurofibromin and p120 GTPase activating protein (GAP) by dietary fatty acids.

Ras immunoprecipitation GTPase assay. The full-length p120 GAP expressed in insect Sf9 cells and the immunoaffinity purified full-length neurofibromin were used. Neurofibromin was readily inhibited by stearic and oleic acid; but p120 GAP was not inhibited even at high concentrations (> 80 microM). Neurofibromin was also inhibited by low concentrations of all the polyunsaturated fatty acids tested (IC50 of 6 to 16 microM). p120 GAP was 2-3 fold less sensitive to inhibition by these fatty acids. The GTPase s

10667358

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Inhibition of neurofibromin and p120 GTPase activating protein (GAP) by dietary fatty acids.

timulatory activity of neurofibromin was also inhibited by arachidonic and oleic acid in the presence of a lipid mixture representing the major lipid components of the cell membrane. Chimeric proteins of neurofibromin and p120 GAP were used to determine that differential sensitivity to fatty acid inhibition maps to the catalytic domain of the proteins. These results indicated that fatty acids can modulate the GTPase function of the c-Ha-Ras protein by inhibiting the GTPase stimulatory activity of two Ras re

10667358

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Inhibition of neurofibromin and p120 GTPase activating protein (GAP) by dietary fatty acids.

gulators; full-length neurofibromin and p120 GAP; at physiologically relevant concentrations in vitro.

10667358

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[Use of Ankum-2 fermenter in solving special problems of bacterial nutrition in vaccine production].

nan

6360070

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[Immunogenicity and pathogenicity factors of Corynebacterium pyogenes. 1. Trials of immunity development against Corynebacterium pyogenes infections in the mouse model].

nan

6360071

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[The value of computer tomography in the diagnosis of chest wall tumors].

Conventional roentgen diagnosis of chest wall tumors; especially with reference to the expansion in the soft tissue; is limited. The computed tomographic examinations in 35 patients with tumors of the chest wall and pleura demonstrate the great value of this method for localization and the judgement of tumor spreading. CT-controlled fine-needle biopsy can clarify the diagnosis. Computed tomography is important for decision and planning of surgical and radiation therapy.

6360072

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Hyperacute rejection of xenografts. I. Differences in affinity to ConA--Sepharose of IgG--fraction of the affluent and effluent blood.

The immunoglobulin fraction from affluent and effluent sera from the rabbit liver transplanted to a dog partially purified on ion exchange DEAE--Sephadox A-50 was chromatographed on ConA-Sepharose. The picture of SDS polyacrylamide slab gel electrophoresis (PAGE) showed in the xenograft serum a considerably higher intensity of bands corresponding to the mobility of heavy and light IgG chains. This suggested the presence of glycoproteins coupled to IgG. Immunoelectrophoresis proved occurrence in the transpla

6360073

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Hyperacute rejection of xenografts. I. Differences in affinity to ConA--Sepharose of IgG--fraction of the affluent and effluent blood.

nt serum of at least six additional components precipitating with whole anti-dog serum. These components could be either glycoprotein antigens or complement components; free or bound to IgG subclasses.

6360073

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Hyperacute rejection of xenografts. II. Isolation of individual components of the graft effluent serum.

Separation of glycoprotein components from Con A-Sepharose in acid solution gave an electrophoretic picture of transplant serum containing a "double band" which was not found on any electrophoresis of fractions eluted from Con A-Sepharose at pH 7.4. This band corresponded with mobility to proteins of molecular weight higher than heavy IgG chains. We assume that at pH 3 the observed picture of the new protein may be a glycoprotein antigen dissociated from the immunological complex. Immunophoresis of the tran

6360074

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Hyperacute rejection of xenografts. II. Isolation of individual components of the graft effluent serum.

splant serum fraction confirmed our assumption that at pH 3 there appeared a new component absent at pH 7.4. Our attempts at separating this component on Sephadex G-150 were unsuccessful.

6360074

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Impaired bactericidal activity of cord sera against Salmonella strains.

Weaker bactericidal activity of cord sera against Salmonella bacilli was shown in comparison with maternal venous sera. No correlation was found between the bactericidal activity and the levels of complement; immunoglobulins and lysozyme in cord sera. Worthy of notice is detected in these researches specificity of bactericidal action of cord sera.

6360075

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The influence of methylpropionic acid and pyridazinone-3 derivatives on some immunologic and hemopoietic functions.

There was studied the influence on the cell-mediated and humoral response in vivo manifested by selected methylpropionic acid and pyridazinone-3 derivatives which had been found to possess strong immunotropic effects in the in vitro screening previously. It was shown that the compounds were generally poorly tolerated by animals; and they exerted only weak suppressive effects on antibody production; the contact hypersensitivity and survival of skin grafts. This immunosuppressive activity was accompanied by a

6360076

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The influence of methylpropionic acid and pyridazinone-3 derivatives on some immunologic and hemopoietic functions.

slight decrease in the number of spleen colony forming cells (CFU-s). Only limited correlation between the biological activity of the preparations and their chemical structure was found.

6360076

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Recipient race as a risk factor in renal transplantation.

We analyzed 118 renal transplants performed from November 1977 through October 1981 to determine the effect of recipient race on graft and patient survival. Fifty-one cadaver and three living related transplants were performed in the black recipients and 41 cadaver and 23 living related transplants in the white recipients. No significant differences existed between the groups in regard to age; incidence of pretransplant nephrectomy or splenectomy; warm ischemia time; perfusion time; panel-reactive alloantib

6360077

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Recipient race as a risk factor in renal transplantation.

ody (PRA) status; or number of pretransplant blood transfusions. The mean HLA-A and -B locus match was significantly less in black cadaver recipients and the incidence of malignant hypertension was significantly greater in black recipients. The one-year graft survival rate was 54.9% for black cadaver recipients and 48.7% for white cadaver recipients with a corresponding patient survival rate of 86.2% and 85.3%. The one-year graft survival rate for living-related recipients was 100% for blacks and 73.9% for

6360077

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Recipient race as a risk factor in renal transplantation.

whites with a corresponding patient survival rate of 100% and 86.9%. These results were not significantly different. When the recipients were matched for age; pretransplant transfusions; HLA-A and -B locus matching; and PRA status; no difference in transplant outcome was identified. We concluded that recipient race is not of prognostic significance in determining the outcome of either cadaver or living related donor transplantation.

6360077

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Ashley A. Miles and the prevention of infection following surgery. Presidential address.

nan

6360078

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Effect of abdominal operations on survival after septic challenge in normal rats.

We evaluated the effect of 60% small-bowel enterectomy that removed 75% of Peyer's patches; and the effects of lesser abdominal operations; on the survival of rats following inducement of peritonitis. We divided 286 female Fischer rats weighing 140 to 200 g into four experimental and two control groups. Following enterectomy; rats recovered for ten to 14 days before peritonitis was induced by intraperitoneal injection of 0.7 mL/100 g of body weight of a solution of 4% hemoglobin and Escherichia coli (10(9)/

6360079

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Effect of abdominal operations on survival after septic challenge in normal rats.

mL). At 48 hours after enterectomy; the survival rate was better than that in rats not operated on or anesthetized. Survival rates for rats having lesser intra-abdominal operations were significantly greater after peritonitis than the rates for controls; but were similar to rates for rats having enterectomies. Our results suggest that intra-abdominal operation of minimal or large magnitude is associated with improved survival from hemoglobin-E coli adjuvant peritonitis.

6360079

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Persistent baculovirus infections: Spodoptera frugiperda NPV and Autographa californica NPV in Spodoptera frugiperda cells.

Establishment of a persistent infection of Spodoptera frugiperda nuclear polyhedrosis virus (NPV) in Spodoptera frugiperda (S.f.) cells occurred in three phases: the first phase was characterised by high levels of cell infection and death; the second phase by decreasing cell infection levels leading to the final phase where less than one per cent of the cells were infected during any subculture. The virus persisted at this level of infection provided the cells were maintained by regular subculturing and inc

6360080

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Persistent baculovirus infections: Spodoptera frugiperda NPV and Autographa californica NPV in Spodoptera frugiperda cells.

ubated at the optimum growth temperature of 27 degrees C. Because of the low proportion of cells infected; cultures of virus-free cells could be selected ('cured') by dilution of the persistent infection without the use of viral antiserum. Unlike the parent S.f. cells; cultures of cured cells were partially resistant to infection with S. frugiperda NPV or infection with an unrelated baculovirus Autographa californica NPV. A. californica NPV; which is cytolytic for the parent S.f. cell line; established a pe

6360080

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Persistent baculovirus infections: Spodoptera frugiperda NPV and Autographa californica NPV in Spodoptera frugiperda cells.

rsistent infection in the cured cells. The establishment pattern was similar to that previously found for S. frugiperda NPV and only one to five per cent of the cells were infected at equilibrium. Cured cells from the A. californica NPV persistent infection were highly resistant to infection with both S. frugiperda NPV and A. californica NPV. All attempts to find a viral interference phenomenon to explain the resistance of the cured cells were unsuccessful. All cell types adsorbed virus equally well. Slower

6360080

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Persistent baculovirus infections: Spodoptera frugiperda NPV and Autographa californica NPV in Spodoptera frugiperda cells.

growth of S.f. cells cured from the persistent A. californica NPV infection is the only difference so far observed between any of the S.f. cell types.

6360080

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[Age and sex characteristics of the mineralization of hand bones in man].

nan

6360081

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[Retino-pulvinar pathway of the cat brain].

Peculiarities on axonal distribution and termination of the retinal ganglionar cells within the limits of the thalamic pulvinar nuclei have been studied in 10 cats by means of the radioautography method combined with silver nitrate impregnation (Fink--Heimer technique). The ganglionar cells have projections on two pulvinar nuclei -- the lateral and the inferior. The medial pulvinar nucleus has no similar connections. The retinal projections in the pulvinar nuclear complex are bilateral and nearly symmetrica

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[Retino-pulvinar pathway of the cat brain].

l; the contralateral projections of the pathway somewhat predominate.

6360082

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[Growth of the caudate nucleus during postnatal ontogeny in the dog, rat and guinea pig].

The development of one of the largest nuclei in the basal ganglia -- the caudate nucleus -- in the dog; rat and guinea pig continues after birth. The growth processes of the neural cell bodies in the caudate nucleus coinside with the development of the animal's movement performed by itself and are most intensive up to the ontogenetic stage; when in all three species the brain mass is equal to 60% of the brain mass in a mature animal. An indirect index demonstrating the dendritic network development -- the d

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[Growth of the caudate nucleus during postnatal ontogeny in the dog, rat and guinea pig].

ensity of the neurons arrangement -- becomes equal to the value specific for a mature animal much later in the postnatal ontogenesis even in a full-term born guinea pig. The postponed morphological maturation of the structure can be considered as an evidence of a certain connection of the structure in question not only with motor activity; but with inhibition; as well.

6360083

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[Axons of sympathetic neurocytes and their relation to lemmocytes during postnatal ontogeny in the rat].

The external carotid nerves have been studied electronmicroscopically in rats at the age of 1; 6; 13; 30 days and 5 months. The growth dynamic of diameter of the axons composing the nerve has been followed; as well as formation of glial membranes around them and quantitative changes of microtubules in the axons. During the first month of life; the average axonal diameter increases more than twice; the content of organells rises in them. Concentration of the microtubules is higher in thin axons (0.1--0.2 mcm

6360084

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[Axons of sympathetic neurocytes and their relation to lemmocytes during postnatal ontogeny in the rat].

); with increasing of their diameter it becomes lower. No correlation between concentration of the microtubules and age of the animal is noted. In newborn rats the glial membranes around the axons are nearly completely absent; by the end of the second week of life; most of the axons already have them. Sometimes; in one groove of the lemmocyte there can be seen several of them. By the first month of life; the axons are situated in individual grooves; this is specific for mature animals. In a 2-week-old rat o

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[Axons of sympathetic neurocytes and their relation to lemmocytes during postnatal ontogeny in the rat].

ne lemmocyte surrounds several dozens of axons; in a mature one--about 5--13.

6360084

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[Critique of methodologic errors in the theory of anthropogenesis].

nan

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[Spiral arrangement of muscular elements in the walls of blood vessels and their role in hemodynamics].

The article claims that contractions of the cardiac left ventricle produce a whirling (turbulent) movement of blood that is maintained in the aorta. In the walls of large and small arteries; as well as in the arteriolar walls; myocytes have a spiral arrangement. Their contraction maintains the turbulent blood stream in the vessels with a small diameter; in spite of the fact that the Reinolds' number for them is rather small. The author considers that while making a mathematical analysis of the blood flowing

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[Spiral arrangement of muscular elements in the walls of blood vessels and their role in hemodynamics].

in the arteries; it is necessary to take into account that the walls of the arterial vessels actively influence the blood stream.

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[Ultrastructure of the endothelial cells of blood capillaries of lymph nodes in the rat].

Ultrastructure of endothelium in the rat popliteal lymph nodes has been studied. The cross section area of the capillary arterial part is 29.9 +/- 1.0; that of the venous part -- 91.2 +/- 1.6; the luminal cross section of the arterial part is 4.90 +/- 0;23; that of the venous part -- 46.8 +/- 1.1 mcm2. Nucleous-cytoplasmic ratio in the endotheliocytes of the arterial part is 1.50 +/- 0.06; that of the venous part -- 2.10 +/- 0.13. The number of microvesicles per 1 mcm of the profile length in the section of

6360087

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[Ultrastructure of the endothelial cells of blood capillaries of lymph nodes in the rat].

the basal surface in a plasmolemma is 1.13 +/- 0.07 both in the arterial and venous parts of the capillary; that of the luminal surface -- 1.35 +/- 0.07 for the arterial part and 0.48 +/- 0.03 for the venous part. The number of free microvessels per 1 mcm2 of the cytoplasmic cross section area is also greater for the arterial part (9.6 +/- 0.8 vs. 7.3 +/- 0.4 in the venous part). Numerical density of free ribosomes in endotheliocytes of the arterial part is 62 +/- 6; in the venous part -- 47 +/- 5 per 1 mc

6360087

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[Ultrastructure of the endothelial cells of blood capillaries of lymph nodes in the rat].

m2 of the cytoplasmic cross section. Numerical density of mitochondria in the venous part is 0.77 +/- 0.11 and in the arterial part -- 0.40 +/- 0.04 per 1 mcm3 of cytoplasm.

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[Forms and factors of the variability of paranasal sinuses].

The form; structural variations; sex variations (connected with zygosityz); right and left positions of the sinuses were studied according to the data obtained while measuring the contours of the frontal; sphenoid and maxillary sinuses in the cranial roentgenograms made in the frontal and sagittal projections. By means of the twin method; relationship of the hereditary and environmental influences on the sinus formation was estimated. The data obtained in 111 Ukrainians (30--60 years of age); inhabitants of

6360088

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[Forms and factors of the variability of paranasal sinuses].

Vinnitsa region; mono- and dizygote twins of both sex were used. Greater dimensions in the male sinuses and a high variability of their size not connected with sex were stated. Among women the dizygote twin had larger dimensions than the monozygote ones. The sinus size is characterized by a predominant right-sided asymmetry. The hereditary effect is clearly seen in the sinus paranasales formation. A decreasing hereditary influence noted in the maxillary sinus is considered as a dependence of its dimensions

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[Forms and factors of the variability of paranasal sinuses].

on the state of the masticatory apparatus.

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[Chief factors in the system of women's physical dimensions].

The investigation has been performed in 670 young (18--20 years-old) Estonian women. They are healthy students from Tartu University having a normal menstrual cycle; or with some slight deviations in it. In every woman 56 body dimensions; including the external obstetric pelvic ones; are analysed. The measurement technique in general corresponds to the classical techniques suggested by V. V. Bunak (1941) and R. Martin (1928). The linear correlation matrix of the body dimensions statistically significant pos

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[Chief factors in the system of women's physical dimensions].

itive correlations have been revealed between all the signs studied; the body mass and length possessing; the highest correlations. When the influence of the body mass and length is eliminated; the usual correlative correlation system is destroyed. Instead of the previous system; where all the signs are statistically positively significantly connected; the only connections remain that include 46% of negative connections and 30% of statistically significant; but very weak connections (the critical value r-0;

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[Chief factors in the system of women's physical dimensions].

088). The factor matrix is calculated on the base of the correlation matrix by means of the main components method. For its rotation the so called method of varimax is used. Three; five and seven factors are rotated (the parts of the initial signs in the total variance are 56; 65; 72%; respectively). The factor analysis also supports the main role of the body mass and length. When the number of the factors and described by them the part of the total variance increases; only some peculiar factors connected w

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[Chief factors in the system of women's physical dimensions].

ith subsystems are added. The factor analysis demonstrates that; besides the body mass and length; there are no other equally important body dimensions which could be used for description of the woman's body structure.

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[Role of muscles stabilizing the human shoulder joint].

Clinical observations of the surgeon-traumatologist demonstrate the role of the muscles inserting to the greater and smaller tubercles of the humerus for fixating the shoulder joint.

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[Structure of the walls of osseous lacunae during their formation].

The osseous lacunae formation in the sponge bone has been studied in the human lumbar vertebrae. Conditionally; this process can be divided into a number of stages. During the first-stage; recesses are formed on the surface of the trabeculae. During the second stage; clearly outlined lacunar edges are formed and mineralization of the fundal collagenous structures is completed. During the third stage; the lacunae are closed. A special attention is paid to changes in the structure and spatial architectonics o

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[Structure of the walls of osseous lacunae during their formation].

f the fibrillar components of the ground osseous substance forming the lacunae.

6360090

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[Improved methodology for detecting flatfoot by the M. O. Fridland method].

nan

6360092

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[Evaluation and comparison of means taking into account the variability of primary measurable objects and individual differences].

nan

6360093

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[Studies of neuromuscular junctions using improved histochemical methods].

nan

6360094

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[Pathologic anatomy at Tartu University].

nan

6360095

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[Zinc-deficient states in man].

Pathology seen in zink deficiency in man is presented. In the antenatal period this deficiency leads to the delivery of immature fetuses and development of congenital malformations. In the postnatal period; zink deficiency can be produced by endogenic; exogenic; and iatrogenic causes. Zink deficient states are characterized by various clinical signs.

6360097

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[Microcirculation and inflammation].

On the basis of the literature analysis and own observations the author concludes that the process of inflammation involves all the components of the microcirculatory bed and the endothelial lining: arterioles; blood precapillaries; capillaries; postcapillaries; venules; lymph capillaries; systems of the interstitial tissue channels as well as the connective tissue rich in hyaluronic acid and proteoglycans. The emergence of all cardinal signs of inflammation is associated with damage of different components

6360096

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[Microcirculation and inflammation].

of the microcirculatory bed. Intensive peroxidation of lipids ("oxidative stress") was observed in the focus of inflammation. Microcirculatory disorders in the inflammation focus are always synchronously accompanied by activation of blood plasma protein systems: coagulation; anticoagulation; kinin; complementary.

6360096

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[Oral contraceptives and cardiovascular complications].

nan

6360098

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[Evaluation of the antihypertensive efficacy of acebutolol, chlorthalidone and the combination of acebutolol and chlorthalidone in the treatment of mild and moderate primary arterial hypertension].

nan

6360100

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[Treatment of arterial hypertension with a combination of hydrochlorothiazide and hydrochloride amiloride].

nan

6360099

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Proper microsurgical nerve suture may impede Wallerian degeneration of completely transected nerves. An electron microscopic study.

Electron microscopic findings on the nerve of the biventer cervicis muscle of the chick; which was completely transected and immediately after submitted to an adequate microsurgical nerve suture; confirmed our previous statement that proper microsurgical nerve suture may impede the Wallerian degeneration that normally occurs in the distal segment of a completely transected nerve.

6360102

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[Captopril in the therapy of resistant hypertension. A multicenter study].

nan

6360101

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Childhood acid maltase deficiency. A clinical, biochemical, and morphologic study of three patients.

Three children; including two siblings and a patient with sporadic glycogenosis type II (childhood form of acid maltase deficiency [AMD] ); were studied clinically; biochemically; and morphologically. In addition to a delay in developmental milestones and mild generalized muscle weakness; nasal vocalization and an electromyographic finding of abnormal insertion voltage; followed by pseudomyotonic discharge; were assumed to be characteristic diagnostic findings for the childhood form of AMD. Since the neutra

6360103

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Childhood acid maltase deficiency. A clinical, biochemical, and morphologic study of three patients.

l maltase activity was highest in the muscle biopsy specimen from the patient with the least severe weakness; the enzyme may play a role in reducing muscle involvement. Selective type 2A fiber atrophy and type 2B fiber deficiency in the affected muscles were the common histochemical findings in this particular form of AMD.

6360103

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Application of inhibitor typing in a study of the transmission and retention in the human mouth of the bacterium Streptococcus salivarius.

Inhibitor production (P)-typing was used as a strain marker in epidemiological studies of Streptococcus salivarius. 43 per cent of 180 adult subjects had inhibitory Strep. salivarius strains as components of their oral microbiota. Strains of 13 different P-type patterns were detected and strains of different P-types often co-existed in the same subject. Adults from whom inhibitor-producing Strep. salivarius strains had been isolated retained their characteristic bacteriocinogenic strains over a 3-yr period.

6360104

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Application of inhibitor typing in a study of the transmission and retention in the human mouth of the bacterium Streptococcus salivarius.

A specific Strep. salivarius-inhibitor screening method was used to study oral acquisition of Strep. salivarius by 14 newborn babies. Initially the babies were colonized by a wide variety of strains; many of which were not detected in the mothers' mouths. By the fifth day of life; strains with P-types identical with those in the mother had often become established as quantitatively prominent members of the babies' Strep. salivarius population.

6360104

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Immunochemical comparison of cell-wall antigens of various viridans streptococci, including strain 2A2+3 hot from recurrent oral aphthous ulceration in man.

Several studies suggest that patients with recurrent aphthous ulceration show cell-mediated and humoral immunity to antigens of Streptococcus sanguis; particularly strain 2A2+3 HOT which is said to be antigenically similar or identical to Strep. sanguis strain ATCC 10556. However; physiological classification as well as analysis of the immunologically dominant cell-wall antigens by immunoelectrophoresis and indirect immunofluorescence showed that the strain is actually a strain of Streptococcus mitis and is

6360105

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Immunochemical comparison of cell-wall antigens of various viridans streptococci, including strain 2A2+3 hot from recurrent oral aphthous ulceration in man.

antigenically more like ATCC 10557 than ATCC 10556. The findings illustrate the antigenic heterogeneity of the Strep. sanguis and Strep. mitis taxons; and demonstrate the need for antigenic analysis of viridans streptococcal strains used in immunological studies of the aetiology of disease and in antiserum production. Commercial streptococcal group and antisera were also tested.

6360105

[ null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null, null ]

Inactivation and stabilization of IgA protease from the human oral bacterium Streptococcus sanguis.

The oral bacterium; Streptococcus sanguis; secretes an extracellular protease which specifically cleaves immunoglobulin A (IgA). During in vitro growth of Strep. sanguis at 37 degrees C the IgA protease was completely inactivated within 2 h. Lowering the growth temperature to 31 degrees C reduced the inactivation rate 50 per cent and a doubling of enzyme yield was obtained. The IgA protease could be stabilized by the presence of whole human saliva; by a low concentration of IgA; or by inhibition of non-spec

6360106

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Inactivation and stabilization of IgA protease from the human oral bacterium Streptococcus sanguis.

ific protease activity. Therefore; the inactivation of IgA protease appeared to be the cumulative result of thermal denaturation and inactivation by non-specific proteases.

6360106

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400th anniversary of Batisch's Der Augendienst.

nan

6360107

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Iron deposition in the corneal graft. Another corneal iron line.

Linear iron deposits in the corneal epithelium are well-documented phenomena in a variety of circumstances; both normal and pathologic. A characteristic annular pigmented line; appearing clinically as an "iron" line; occurred in the donor epithelium of approximately 13% of corneal grafts with retained sutures. Eight cases of normally functioning grafts had iron lines located just central to the sutures. These lines appeared at various intervals postoperatively and did not correlate with age or race. They we

6360108

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Iron deposition in the corneal graft. Another corneal iron line.

re frequently found in association with other surface-related epithelial and subepithelial phenomena and were believed to be related to peripheral corneal topography and the lid-cornea interface. Although they are clinically iron; their precise histochemistry; cause; source; and natural history are yet to be determined.

6360108

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Corneal iron lines after refractive keratoplasty.

Twenty-three of 55 patients who underwent refractive keratoplasty for the correction of aphakia were found to have a pigmented corneal epithelial line similar to the Fleischer ring. In 21 of 23 cases; the pigmented ring was adjacent to the superficial keratectomy scar that resulted from the keratorefractive operation. In two cases; the pigmented line was located central to the lamellar keratectomy scar. Histopathologic study demonstrated that the line was due to iron in the form of ferritin particles deposi

6360109

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Corneal iron lines after refractive keratoplasty.

ted within basal corneal epithelial cells. We believe that the steep anterior corneal curvature (average; 51.45 diopters) and changes in corneal topography at or central to the margin of the lamellar keratoplasty may lead to malapposition of the eyelid to the cornea and cause disturbances in the precorneal tear film. Iron from the tears may then be deposited in the corneal epithelium in areas of tear pooling.

6360109

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Combination therapy for dendritic keratitis with acyclovir and alpha-interferon.

Fifty-nine patients with superficial herpetic keratitis were treated with 3% acyclovir ointment five times a day in combination with alpha-interferon (30 million IU/mL) or albumin-placebo once a day in a stratified double-masked clinical trial. All patients had minimal wiping of the superficial lesion to isolate virus. The healing time of the corneal ulcers was substantially lower with the combination of acyclovir and interferon than with the combination of acyclovir and placebo. Only minor toxic effects we

6360110

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Combination therapy for dendritic keratitis with acyclovir and alpha-interferon.

re observed. The combination of acyclovir and interferon appears to be the best presently known treatment for dendritic keratitis.

6360110

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