Issue 1:
Received this error. For some additional info, I am only using the std/path module and some function from the Deno global.

thread 'main' panicked at 'already borrowed: BorrowMutError', /rustc/4fb7144ed159f94491249e86d5bbd033b5d60550/src/libcore/cell.rs:878:9
stack backtrace:
0: backtrace::backtrace::libunwind::trace
at /cargo/registry/src/github.com-1ecc6299db9ec823/backtrace-0.3.44/src/backtrace/libunwind.rs:86
1: backtrace::backtrace::trace_unsynchronized
at /cargo/registry/src/github.com-1ecc6299db9ec823/backtrace-0.3.44/src/backtrace/mod.rs:66
2: std::sys_common::backtrace::_print_fmt
at src/libstd/sys_common/backtrace.rs:78
3: <std::sys_common::backtrace::_print::DisplayBacktrace as core::fmt::Display>::fmt
at src/libstd/sys_common/backtrace.rs:59
4: core::fmt::write
at src/libcore/fmt/mod.rs:1063
5: std::io::Write::write_fmt
at src/libstd/io/mod.rs:1426
6: std::sys_common::backtrace::_print
at src/libstd/sys_common/backtrace.rs:62
7: std::sys_common::backtrace::print
at src/libstd/sys_common/backtrace.rs:49
8: std::panicking::default_hook::{{closure}}
at src/libstd/panicking.rs:204
9: std::panicking::default_hook
at src/libstd/panicking.rs:224
10: std::panicking::rust_panic_with_hook
at src/libstd/panicking.rs:470
11: rust_begin_unwind
at src/libstd/panicking.rs:378
12: core::panicking::panic_fmt
at src/libcore/panicking.rs:85
13: core::option::expect_none_failed
at src/libcore/option.rs:1211
14: deno_core::bindings::send
15: <extern "C" fn(A0) .> R as rusty_v8::support::CFnFrom<F>>::mapping::c_fn
16: _ZN2v88internal25FunctionCallbackArguments4CallENS0_15CallHandlerInfoE
17: _ZN2v88internal12_GLOBAL__N_119HandleApiCallHelperILb0EEENS0_11MaybeHandleINS0_6ObjectEEEPNS0_7IsolateENS0_6HandleINS0_10HeapObjectEEESA_NS8_INS0_20FunctionTemplateInfoEEENS8_IS4_EENS0_16BuiltinArgumentsE
18: _ZN2v88internalL26Builtin_Impl_HandleApiCallENS0_16BuiltinArgumentsEPNS0_7IsolateE
19: Builtins_CEntry_Return1_DontSaveFPRegs_ArgvOnStack_BuiltinExit
note: Some details are omitted, run with `RUST_BACKTRACE=full` for a verbose backtrace.
fatal runtime error: failed to initiate panic, error 5
Aborted

Issue 2:
C:\workspace>deno-1.0.3.exe
Deno 1.0.3
exit using ctrl+d or close()
> crypto.getRandomValues(new Uint8Array(10))
Uint8Array(10) [
255, 146, 102, 81,
25, 238, 144, 127,
185, 250
]
>

C:\workspace\deno>deno
Deno 1.0.4
exit using ctrl+d or close()
> crypto.getRandomValues(new Uint8Array(10))
thread 'main' panicked at 'already borrowed: BorrowMutError', /rustc/4fb7144ed159f94491249e86d5bbd033b5d60550\src\libcore\cell.rs:878:9
note: run with `RUST_BACKTRACE=1` environment variable to display a backtrace

C:\workspace\deno>

C:\workspace\deno>set RUST_BACKTRACE=full& deno
Deno 1.0.4
exit using ctrl+d or close()
> crypto.getRandomValues(new Uint8Array(10))
thread 'main' panicked at 'already borrowed: BorrowMutError', /rustc/4fb7144ed159f94491249e86d5bbd033b5d60550\src\libcore\cell.rs:878:9
stack backtrace:
0: 0x7ff7eaab92df - CrashForExceptionInNonABICompliantCodeRange
1: 0x7ff7eaada82b - CrashForExceptionInNonABICompliantCodeRange
2: 0x7ff7eaaaf09c - CrashForExceptionInNonABICompliantCodeRange
3: 0x7ff7eaabc96c - CrashForExceptionInNonABICompliantCodeRange
4: 0x7ff7eaabc5bf - CrashForExceptionInNonABICompliantCodeRange
5: 0x7ff7eaabd147 - CrashForExceptionInNonABICompliantCodeRange
6: 0x7ff7eaabcccf - CrashForExceptionInNonABICompliantCodeRange
7: 0x7ff7eaad9130 - CrashForExceptionInNonABICompliantCodeRange
8: 0x7ff7eaad8f83 - CrashForExceptionInNonABICompliantCodeRange
9: 0x7ff7e9fdd070 - <unknown>
10: 0x7ff7e9fcf8ab - <unknown>
11: 0x7ff7ea4731bb - CrashForExceptionInNonABICompliantCodeRange
12: 0x7ff7ea4725f8 - CrashForExceptionInNonABICompliantCodeRange
13: 0x7ff7ea471b46 - CrashForExceptionInNonABICompliantCodeRange
14: 0x7ff7ea471767 - CrashForExceptionInNonABICompliantCodeRange
15: 0x7ff7ea2842fc - CrashForExceptionInNonABICompliantCodeRange
16: 0x7ff7ea216755 - CrashForExceptionInNonABICompliantCodeRange
17: 0x7ff7ea20ff1f - CrashForExceptionInNonABICompliantCodeRange
18: 0x7ff7ea216755 - CrashForExceptionInNonABICompliantCodeRange
19: 0x7ff7ea216755 - CrashForExceptionInNonABICompliantCodeRange
20: 0x7ff7ea21421e - CrashForExceptionInNonABICompliantCodeRange
21: 0x7ff7ea213e0c - CrashForExceptionInNonABICompliantCodeRange
22: 0x7ff7ea0d57a7 - <unknown>
23: 0x7ff7ea0d4b2a - <unknown>
24: 0x7ff7ea003be3 - <unknown>
25: 0x7ff7e9ffb6a1 - <unknown>
26: 0x7ff7e9fdde9d - <unknown>
27: 0x7ff7e9fcf71b - <unknown>
28: 0x7ff7ea4731bb - CrashForExceptionInNonABICompliantCodeRange
29: 0x7ff7ea4725f8 - CrashForExceptionInNonABICompliantCodeRange
30: 0x7ff7ea471b46 - CrashForExceptionInNonABICompliantCodeRange
31: 0x7ff7ea471767 - CrashForExceptionInNonABICompliantCodeRange
32: 0x7ff7ea2842fc - CrashForExceptionInNonABICompliantCodeRange
33: 0x7ff7ea216755 - CrashForExceptionInNonABICompliantCodeRange
34: 0x7ff7ea216755 - CrashForExceptionInNonABICompliantCodeRange
35: 0x7ff7ea245a51 - CrashForExceptionInNonABICompliantCodeRange
36: 0x7ff7ea2c930f - CrashForExceptionInNonABICompliantCodeRange
37: 0x7ff7ea237dad - CrashForExceptionInNonABICompliantCodeRange
38: 0x7ff7ea21410c - CrashForExceptionInNonABICompliantCodeRange
39: 0x7ff7ea0d56de - <unknown>
40: 0x7ff7ea0d5dac - <unknown>
41: 0x7ff7ea0d5eaf - <unknown>
42: 0x7ff7ea199b28 - CrashForExceptionInNonABICompliantCodeRange
43: 0x7ff7ea199905 - CrashForExceptionInNonABICompliantCodeRange
44: 0x7ff7ea035ae1 - <unknown>
45: 0x7ff7ea010321 - <unknown>
46: 0x7ff7e9ffb436 - <unknown>
47: 0x7ff7e9fb9380 - <unknown>
48: 0x7ff7e9fb7ce0 - <unknown>
49: 0x7ff7e9fc3179 - <unknown>
50: 0x7ff7e98121fa - <unknown>
51: 0x7ff7e96f250e - <unknown>
52: 0x7ff7e9787669 - <unknown>
53: 0x7ff7e9741a54 - <unknown>
54: 0x7ff7e98c16f5 - <unknown>
55: 0x7ff7e9764f20 - <unknown>
56: 0x7ff7e9948d26 - <unknown>
57: 0x7ff7eaabcb67 - CrashForExceptionInNonABICompliantCodeRange
58: 0x7ff7eaacab92 - CrashForExceptionInNonABICompliantCodeRange
59: 0x7ff7eaabd388 - CrashForExceptionInNonABICompliantCodeRange
60: 0x7ff7e9768da7 - <unknown>
61: 0x7ff7eaaeaf44 - CrashForExceptionInNonABICompliantCodeRange
62: 0x7ffd92e77bd4 - BaseThreadInitThunk
63: 0x7ffd9398ce51 - RtlUserThreadStart

C:\workspace\deno>