formatting dataset card 2
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README.md
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"pmid": "34661004",
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"introduction": [
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"<title>Introduction</title>",
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"<p>Medicinal plants are\nknown to possess several primary and secondary\nmetabolites. The secondary metabolites
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"<p>Genus <italic>Clerodendrum</italic> belonging to\nfamily Verbenaceae or Lamiaceae has more than 500 species.
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],
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"methods": [
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"<title>DPPH Method</title>",
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"<p>The most effective and popular method of\nantioxidant evaluation is the DPPH radical scavenging method. Better
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],
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"results": [
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"<title>Results</title>",
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"<p>The phytochemical screening of the flower extract indicated the\npresence of carbohydrates, tannins, phenolics,
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"<p>The total phenolic content,<sup> ##REF## </sup> as quantified\nby Folin-Ciocalteu\u2019s method, indicates the highest
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"<p>Antioxidant activity of the extracts was evaluated by four different\nmethods.<sup> ##REF## </sup> Antioxidants have a high
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"<p>DPPH is widely used as an evaluation technique due\nto its ease\nof reaction. In the ABTS assay method, radical scavenging
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"<p>Nitric oxide radical scavenging activity results of\nthe extract\nwere evaluated by comparing with standard gallic acid. Nitric
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"<p>Reducing power ability of the extracts was determined\nusing potassium\nferricyanide. The ability of the extract to reduce potassium
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"<p>An acute oral toxicity\nstudy of the alcoholic extract at a concentration\nof 2000 mg/kg b.w. revealed that the extract is safe up to the abovementioned\nconcentration range. Hepatoprotective investigation was carried out\nwith the CCl<sub>4</sub> intoxicated model. The liver enzymes and\nprotein levels were checked for all groups of animals, and the results\nare depicted in ##TAB## and <ext-link xmlns:xlink=\"http://www.w3.org/1999/xlink\" ext-link-type=\"uri\" xlink:href=\"https://pubs.acs.org/doi/suppl/10.1021/acsomega.1c03722/suppl_file/ao1c03722_si_001.pdf\">Figure S4</ext-link> (Supporting Information).</p>",
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"<p>The enzyme activities associated\nwith liver functions are good\nbiomarkers for the evaluation of hepatoprotective activity of medicinal\nplants. SGOT and SGPT are enzymes present in the hepatocytes, and\ntheir leakage into the blood stream is observed during cell damage.\nThe level of SGOT is known to increase during cardiac or skeletal\nmuscle damage. ALP is an enzyme which is present in the biliary duct\nlining of liver. The estimation of total bilirubin depicts the depth\nof jaundice and also indicates the severity of liver damage. The decrease\nin the total protein level is an indicator of liver damage caused\nby insignificant protein synthesis.</p>",
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"<p>In the normal control group,\nthe values of SGOT, SGPT, ALP, total\nand direct bilirubin, and protein content were found to be 59.83 \u00b1\n6.25, 52.83 \u00b1 5.71, 101.5 \u00b1 7.92 IU/L, 0.703 \u00b1 0.05,\n0.163 \u00b1 0.02 mg/dL, and 8.47 \u00b1 0.05 g/dL, respectively.\nHowever, the CCl<sub>4</sub> intoxicated control group displayed a\nsignificant increase in these values, like SGOT (145.83 \u00b1 10.91\nIU/L), SGPT (112.17 \u00b1 7.47 IU/L), ALP (324.17 \u00b1 8.70 IU/L),\ntotal bilirubin (1.42 \u00b1 0.11 mg/dL), and direct bilirubin (0.34\n\u00b1 0.06 mg/dL), and a significant decrease in the total protein\ncontent (6.28 \u00b1 0.08 g/dL). CPFA at a concentration of 400 mg/kg\nhas shown a significant decrease in the serum enzymes like SGOT 59.83\n\u00b1 1.70 IU/L, SGPT 58.67 \u00b1 2.63 IU/L, ALP 120.33 \u00b1 2.63\nIU/L, total bilirubin 0.638 \u00b1 0.03 mg/dL, and direct bilirubin\n0.14 \u00b1 0.01 mg/dL and a significant increase in the total protein\ncontent 8.19 \u00b1 0.02 g/dL, as compared to the toxic control group.\nA liver histopathological study also supported the protective effect\nof the extracts compared to the toxic control group. The images are\nrepresented in ##FIG## .</p>",
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"<p>Column chromatographic analysis of the extract was carried out\nwith the universal solvent system that resulted in 13 different fractions.\nPhytochemical screening of these fractions revealed the presence of\nflavonoids, phenolics, and tannins. The results are depicted in ##TAB## .</p>",
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"<p>Total phenolic and flavonoid contents\nwere estimated for all the\nabove fractions. Out of 13 fractions, fractions 5 and 9 showed the\nhighest amount of flavonoids and phenolics. The total phenolic content\nof fraction 5 and 9 was 284.91 \u00b1 6.03 and 378.31 \u00b1 3.15\nmg GAE/g, respectively, and their flavonoid content was evaluated\nas 333.82 \u00b1 1.39 and 380.33 \u00b1 1.55 mg QE/g, respectively\n( ##TAB## ).</p>",
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"<p>Their hepatoprotective\nevaluation was carried out by an <italic>in vitro</italic> model using\ngoat liver slice culture for fractions\n5 and 9 (highlighted in ##TAB## ) that was estimated to have higher contents of phenolics\nand flavonoids. It was revealed that fraction 9 has much better activity,\nas compared to the toxic control group. [ ##TAB## , <ext-link xmlns:xlink=\"http://www.w3.org/1999/xlink\" ext-link-type=\"uri\" xlink:href=\"https://pubs.acs.org/doi/suppl/10.1021/acsomega.1c03722/suppl_file/ao1c03722_si_001.pdf\">Figure S5</ext-link> (Supporting\nInformation)].</p>",
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"<p>GC\u2013MS analyses of the fraction 5 and 9 were\ncarried out\nto identify the compounds that are responsible for the exhibited activity.\nThe spectrum of fraction 9 is shown in ##FIG## and fraction 5 in <ext-link xmlns:xlink=\"http://www.w3.org/1999/xlink\" ext-link-type=\"uri\" xlink:href=\"https://pubs.acs.org/doi/suppl/10.1021/acsomega.1c03722/suppl_file/ao1c03722_si_001.pdf\">Figure S6</ext-link> (Supporting Information). From the library search, it was\nrevealed that the peak corresponding to 105.6 could be due to glyceric\nacid, peak of 169.2 could be due to gallic acid, peak of 207.35 could\nbe due to pilocarpine, and peak of 281.39 could be due to pangamic\nacid.</p>",
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"<p>Further HPTLC analysis was carried out for the alcoholic extract\nof <italic>C. paniculatum</italic> flower. The active\nfractions 5 and 9, as separated by column chromatography along with\nstandard quercetin were considered for evaluation. The solvent mixture\nchloroform/ethyl acetate/formic acid in the ratio 6:4:1 was used as\nthe mobile phase. Silica gel 60 F 254 HPTLC plates were selected for\nanalysis, and the plates were observed under white light and 254 and\n366 nm. The presence of quercetin was confirmed and quantified. The\nimages are depicted in ##FIG## , and the respective chromatograms of the crude extract, the\nfractions under investigation along with the standard quercetin, are\nshown in <ext-link xmlns:xlink=\"http://www.w3.org/1999/xlink\" ext-link-type=\"uri\" xlink:href=\"https://pubs.acs.org/doi/suppl/10.1021/acsomega.1c03722/suppl_file/ao1c03722_si_001.pdf\">Figure S7</ext-link> (Supporting Information).</p>",
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"<p>As quantified from HPLC chromatogram\nunder 254 nm, the amount of\nquercetin present in the alcoholic extract, fraction 5, and fraction\n9 was 38.0, 34.6, and 49.6%, respectively.</p>"
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],
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"discussion": [
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"<title>Discussion</title>",
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"<p>The\nliver, the major metabolic organ of our body, may have toxicity\ndue to various drugs like alcohol, anabolic steroids
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"<p>Internal antioxidant deficiency can be overcome by\nsupplementing\nwith external sources. Since polyphenolics are known to have
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],
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"conclusion": [
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"<title>Conclusions</title>",
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"<p>The implication on the\npharmacological properties from the flower\nextract
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],
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"front": [
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"<p content-type=\"toc-graphic\"> ##GRAPH## </p>",
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"<p>The aim of the presented\nwork involves the isolation, characterization,\nand evaluation of hepatoprotective potential of
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],
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"body": [
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"<title>Experimental\nSection</title>",
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"<title>Chemicals and Reagents</title>",
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"<p>The chemicals and reagents used\nfor the experiments carried out for the present investigation were\npurchased from
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"<title>Plant Collection</title>",
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"<p><italic>C. paniculatum</italic> flowers were collected from Malappuram, Kerala during August to\nOctober.
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"<title>Preparation of Plant Extracts</title>",
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"<p>The flowers weighing\n\u223c300 g were collected and dried under shade. Successively,\nsolvent extraction was carried out using
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"<title>Preliminary Phytochemical Screening</title>",
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"<p>Preliminary qualitative\nanalysis was carried out for detecting the presence of various classes\nof compounds like alkaloids,
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"<title>Determination\nof Total Phenolic and Flavonoid Contents</title>",
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"<p>The Folin\u2013Ciocalteau\nmethod was used for the quantitative\ndetermination of phenolics in each extract. 1 mL of the extract was\nmixed with 1 mL of Folin-Ciocalteu\u2019s reagent. Then, 3 mL of\nsodium carbonate solution was added. The whole mixture was incubated\nfor 2 h, and absorbance was measured at 725 nm.<sup> ##UREF## </sup></p>",
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"<p>The total flavonoid content was estimated using the\naluminium chloride colorimetric method. 0.5 mL of the extract was\nmixed with 2 mL of water and 0.15 mL of NaNO<sub>2</sub> followed\nby the addition of 0.15 mL of 6% AlCl<sub>3</sub> solution. After\n6 min, 2 mL of 4% sodium hydroxide solution was added, and volume\nwas maintained to 5 mL using distilled water. Absorbance was measured\nat 510 nm.<sup> ##REF## </sup></p>",
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"<title><italic>In Vitro</italic> Assays</title>",
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"<title>ABTS Method</title>",
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"<p>In this method, the ABTS radical was generated\nby the oxidation of ABTS with potassium persulfate. For preparing\nABTS solution, 7 mM aqueous ABTS solution and 2.45 mM potassium per\nsulfate were mixed together. The solution was incubated in the dark\nat 29 \u00b0C for 14 h. The working solution was prepared by diluting\nthe previously prepared solution with phosphate buffer (pH 7.4). 50\n\u03bcL of the extract was mixed with 3 mL of the freshly prepared\nsolution and was allowed to stand for 20 min. After the incubation\ntime, absorbance was measured at 734 nm. The percentage inhibition\nwas measured using the above equation.<sup> ##UREF## </sup></p>",
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"<title>Nitric Oxide Radical Inhibitory Assay</title>",
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"<p>Different concentrations\nof plant extracts were mixed with 1.5 mL of 5 mM sodium nitroprusside\nin phosphate buffered saline (pH 7.4). The solution was mixed together\nand incubated at 25 \u00b0C for 3 h. After the incubation time, 1.5\nmL of the Griess reagent (2% phosphoric acid, 1% sulfanilamide, and\n0.1% <italic>N</italic>-1-naphthyl ethylene diamine dihydrochloride)\nwas added to the reaction mixture. Absorbance of the reaction mixture\nwas measured at 546 nm with reference to standard gallic acid. The\npercentage inhibition was also measured.<sup> ##UREF## , ##REF## </sup></p>",
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"<title>Reducing Power Assay</title>",
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"<p>In this method, better antioxidant\nactivity was represented by an increase in the absorbance of the reaction\nmixture. Potassium ferricyanide, ferric chloride, and trichloroacetic\nacid produce a colored complex with the antioxidant compounds, and\nits absorbance can be measured at 700 nm. 2.5 mL of phosphate buffer\n(0.2 M, pH 6.6) and 2.5 mL of potassium ferricyanide were added to\n10 mg/mL samples. The resulting mixture was incubated at 50 \u00b0C\nfor 20 min. After the incubation period, 2.5 mL of trichloroacetic\nacid was added to the mixture, and the upper layer of the resulting\nmixture was collected by the 10 min centrifugation process. To 5 mL\nof above liquid, 5 mL of distilled water and 1 mL of ferric chloride\n(0.1% w/v) were added, and absorbance was measured at 700 nm.<sup> ##REF## , ##REF## </sup></p>",
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"<title>Statistical Analysis</title>",
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"<p>All the procedures were carried\nout in triplicates, and the results were expressed as the mean \u00b1\nstandard deviation. The statistical analyses were carried out using\nSPSS software version 20.</p>",
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"<title><italic>In Vivo</italic> Animal Experiments</title>",
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"<title>Selection\nof Animals</title>",
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"<p>Female Wistar Albino rats weighing\n100\u2013130 g were used for the hepatoprotective analysis of the\nalcoholic extract. Standard laboratory conditions were followed for\nanimal maintenance, and they were fed with standard food and water\nad libitum. The experimental protocol was approved by the Al Shifa\nCollege of Pharmacy Institutional Animal Ethical Committee (IAEC)\n(regd. no. 1195/Re/S/08/CPCSEA).</p>",
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"<title>Acute Toxicity Study</title>",
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"<p><italic>C. paniculatum</italic> flower alcoholic\nextract\u2019s acute toxicity was conducted on\nalbino rats, according to the OECD guidelines no. 425. After 12 h\nof fasting, the extract (2000 mg/kg) was administered orally. The\nanimals were observed for 14 days to check mortality, any behavioral\nchanges, any discomforts, and so on<italic>.</italic><sup> ##REF## </sup></p>",
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"<title>CCl<sub>4</sub>-Induced Hepatoprotective\nStudy</title>",
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"<p>Five\ngroups of six animals were selected, and the experiment was conducted\nfor 14 days.</p>",
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"<p>Doses: the animals of the vehicle group (group\nI) received CMC (5 ml/kg b.w.) orally, and CCl<sub>4</sub> in liquid\nparaffin was administered to animals of group II\u2013V <italic>via</italic> subcutaneous route for 14 days. Standard dose (silymarin,\n50 mg/kg b.w.) was administered to group III, and group IV animals\nreceived CPFA1 (200 mg/kg b.w.) by oral route. Group V animals received\nthe CPFA 2 (400 mg/kg b.w.) extract. After 14 days of treatment, all\nthe animals were sacrificed by cervical decapitation, and blood samples\nwere collected by cardiac puncture. Serum was collected by centrifugation\nat 3000 rpm and examined for enzyme analysis such as SGOT, SGPT, ALP,\ntotal and direct bilirubin, and total protein content. Data were analyzed\nby one-way ANOVA followed by Dunnett\u2019s test.<sup> ##REF## \u2212 ##UREF## </sup></p>",
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"<title>Statistical\nAnalysis</title>",
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"<p>The results of the <italic>in\nvivo</italic> experiments conducted were expressed as mean \u00b1\nS.E.M. SPSS software version 20 was used for statistical analysis.</p>",
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"<title>Histopathology</title>",
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"<p>The livers were excised and washed with\nnormal saline. Liver fragments were fixed in 10% buffered formalin\nfollowed by paraffin embedding. Liver sections of 0.5 \u03bcm thickness\nwere taken and stained with the hematoxylin\u2013eosin dye. The\nsections were mounted and microscopically observed for studying histological\nchanges if any.<sup> ##UREF## </sup></p>",
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"<title>Isolation of Compound Using\nColumn Chromatography</title>",
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"<p>Around\n1 g of the alcoholic extract of the plant was loaded into the column,\nand gradient elution was carried out using hexane, ethyl acetate,\nand methanol as the mobile phase.<sup> ##REF## , ##REF## </sup> The solvent\nwas passed through the column at 1 mL per minute under gravity to\nfractionate the sample extract. Each fraction was collected in a test\ntube and was numbered subsequently. The fractions obtained were subjected\nto the qualitative chemical test for identification of tannins, phenolics,\nand flavonoids.<sup> ##UREF## , ##UREF## , ##UREF## </sup> The quantitative estimation for phenolics and flavonoid was carried\nout,<sup> ##UREF## , ##REF## </sup> and the best two fractions were selected\nfor an <italic>in vitro</italic> hepatoprotective activity study using\ngoat liver slice culture.</p>",
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"<title><italic>In Vitro</italic> Hepatoprotective\nStudy</title>",
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"<p>The\nfresh goat livers were obtained from the local market. The liver was\nremoved and transferred to presterilized Krebs Ringer Herpes (KRH)\nmedium. The liver was cut into thin slices ranging from 4 to 6 mg\nusing a sharp blade and was used for the study. Each set weighing\n100 mg contains 20\u201325 slices. Tissues were washed with 10 mL\nof KRH medium in every 10 min over a period of 1 h. The slices were\npreincubated at 37 \u00b0C for 60 min in cotton-plugged beakers containing\n10 mL of KOH. The liver slices were further divided into individual\nculture for respective treatment. All the cultures were incubated\nat constant temperature in a water bath at 37 \u00b0C for 2 h. The\ncells were isolated from the culture medium of each set by centrifuging\nat 3000 rpm for 10 min at 4 \u00b0C, and the corresponding supernatants\nwere assayed for the presence of leaked biochemical markers such as\nalanine transaminase (ALT), aspartate transaminase (AST), alkaline\nphosphatase (ALP), and acid phosphatase (ACP).<sup> ##UREF## \u2212 ##UREF## </sup></p>",
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"<title>Experimental Setup for\nEvaluation of Hepatoprotective Activity</title>",
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"<p><bold>Group 1:</bold> normal control, <bold>Group 2:</bold> toxic\ncontrol<bold>\u2014</bold>CCl<sub>4</sub> (15.5 mM), <bold>Group\n3:</bold> standard (silymarin-50 mM), <bold>Group 4\u20136:</bold><italic>C. paniculatum</italic> alcoholic extract\nat the concentration range of 25\u2013100 \u03bcg/mL, <bold>Group\n7\u20139:</bold> column fraction 5 at the concentration range of\n2.5\u201310 \u03bcg/mL, and <bold>Group 10\u201312:</bold> column\nfraction 9 at the concentration range of 2.5\u201310 \u03bcg/mL.</p>",
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"<title>GC\u2013MS Analyses</title>",
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"<p>Mass spectra were recorded on\na Schimadzu GCMS-QP2020 Gas chromatograph mass spectrometer. The constituents\npresent in various fractions of the extracts were predicted using\nNIST/EPA/NIH mass spectral library\u20142017. The equipment has\na DB 35-MS capillary standard non-polar poly (dimethylsiloxane) column\nwith dimensions of 30 mm \u00d7 0.25 mm ID \u00d7 0.25 \u03bcm film.\nHelium was used as the carrier gas with a flow rate of 1.0 mL/min.\nThe injector was operated at 280 \u00b0C, and the oven temperature\nwas programmed as follows: 70\u2013280 \u00b0C, gradually increased\nby 10 \u00b0C per/min.</p>"
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],
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"back": [
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"<title>Supporting Information Available</title>",
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"<p>The Supporting Information is\navailable free of charge at <ext-link xmlns:xlink=\"http://www.w3.org/1999/xlink\"
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"<title>Supplementary Material</title>",
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"<p>This research\ndid not receive any specific grant from funding agencies in the public,\ncommercial, or not-for-profit sectors.</p>",
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"<p>The authors declare no\ncompeting financial interest.</p>",
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"<title>Acknowledgments</title>",
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"<p>The authors would like to express their sincere\nthanks to the Management of Vellore Institute of Technology, Vellore\nand
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],
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"figure": [
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"<fig id=\"fig1\" position=\"float\"><label>Figure 1</label><caption><p>Determination\nof reducing power for various solvent
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"<fig id=\"fig2\" position=\"float\"><label>Figure 2</label><caption><p>Photographs of hematoxylin/eosin-stained liver sections
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"<fig id=\"fig3\" position=\"float\"><label>Figure 3</label><caption><p>GC\u2013MS chromatogram of fraction 9.</p></caption> ##GRAPH## </fig>",
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"<fig id=\"fig4\" position=\"float\"><label>Figure 4</label><caption><p>HPTLC\nplates observed under (a) normal light and (b) 254 and (c)\n366 nm.</p></caption> ##GRAPH## </fig>"
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],
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"table": [
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"<table-wrap id=\"tbl1\" position=\"float\"><label>Table 1</label><caption><title>Phytochemical Screening for the Flower\nExtract
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"<table-wrap id=\"tbl2\" position=\"float\"><label>Table 2</label><caption><title>Quantification of Total Phenolics\nand Flavonoids in
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"<table-wrap id=\"tbl3\" position=\"float\"><label>Table 3</label><caption><title>Antioxidant\nPotential, as Determined\nby DPPH Assay with the
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"<table-wrap id=\"tbl4\" position=\"float\"><label>Table 4</label><caption><title>Antioxidant Activity, as Evaluated\nby ABTS Assay with the Alcoholic
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"<table-wrap id=\"tbl5\" position=\"float\"><label>Table 5</label><caption><title>Antioxidant Activity, as Determined\nby Nitric Oxide Radical Scavenging Assay
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| 196 |
-
"<table-wrap id=\"tbl6\" position=\"float\"><label>Table 6</label><caption><title>SGOT, SGPT, ALP, Total and Direct\nBilirubin, and Total Protein Levels of All Groups of Animals<xref rid=\"t6fn1\" ref-type=\"table-fn\">a</xref><sup>,</sup><xref rid=\"t6fn2\" ref-type=\"table-fn\">b</xref></title></caption><table frame=\"hsides\" rules=\"groups\" border=\"0\"><colgroup><col align=\"left\"/><col align=\"char\" char=\"\u00b1\"/><col align=\"char\" char=\"\u00b1\"/><col align=\"char\" char=\"\u00b1\"/><col align=\"char\" char=\"\u00b1\"/><col align=\"char\" char=\"\u00b1\"/><col align=\"char\" char=\"\u00b1\"/></colgroup><thead><tr><th style=\"border:none;\" align=\"center\">\u00a0</th><th style=\"border:none;\" align=\"center\" char=\"\u00b1\">\u00a0</th><th style=\"border:none;\" align=\"center\" char=\"\u00b1\">\u00a0</th><th style=\"border:none;\" align=\"center\" char=\"\u00b1\">\u00a0</th><th colspan=\"2\" align=\"center\" char=\"\u00b1\">Bilirubin (mg/dL)<hr/></th><th style=\"border:none;\" align=\"center\" char=\"\u00b1\">\u00a0</th></tr><tr><th style=\"border:none;\" align=\"center\">groups</th><th style=\"border:none;\" align=\"center\" char=\"\u00b1\">SGOT (IU/L)</th><th style=\"border:none;\" align=\"center\" char=\"\u00b1\">SGPT (IU/L)</th><th style=\"border:none;\" align=\"center\" char=\"\u00b1\">ALP (IU/L)</th><th style=\"border:none;\" align=\"center\" char=\"\u00b1\">total</th><th style=\"border:none;\" align=\"center\" char=\"\u00b1\">direct</th><th style=\"border:none;\" align=\"center\" char=\"\u00b1\">total protein (g/dL)</th></tr></thead><tbody><tr><td style=\"border:none;\" align=\"left\">vehicle control</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">59.33\u00a0\u00b1\u00a02.55**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">52.83\u00a0\u00b1\u00a02.33**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">101.5\u00a0\u00b1\u00a07.92**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">0.703\u00a0\u00b1\u00a00.02**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">0.163\u00a0\u00b1\u00a00.01**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">8.47\u00a0\u00b1\u00a00.02**</td></tr><tr><td style=\"border:none;\" align=\"left\">toxic control</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">145.83\u00a0\u00b1\u00a04.45</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">112.17\u00a0\u00b1\u00a03.05</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">324.17\u00a0\u00b1\u00a03.55</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">1.42\u00a0\u00b1\u00a00.05</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">0.34\u00a0\u00b1\u00a00.02</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">6.28\u00a0\u00b1\u00a00.03</td></tr><tr><td style=\"border:none;\" align=\"left\">standard (silymarin)</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">66.33\u00a0\u00b1\u00a02.19**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">56.67\u00a0\u00b1\u00a02.20**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">109.83\u00a0\u00b1\u00a03.21**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">0.752\u00a0\u00b1\u00a00.01**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">0.17\u00a0\u00b1\u00a00.01**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">8.36\u00a0\u00b1\u00a00.02**</td></tr><tr><td style=\"border:none;\" align=\"left\">CPFA (200\u00a0mg/kg)</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">64.67\u00a0\u00b1\u00a02.08**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">62.83\u00a0\u00b1\u00a00.79**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">128.50\u00a0\u00b1\u00a02.88**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">0.787\u00a0\u00b1\u00a00.03**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">0.18\u00a0\u00b1\u00a00.01**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">8.12\u00a0\u00b1\u00a00.01**</td></tr><tr><td style=\"border:none;\" align=\"left\">CPFA (400\u00a0mg/kg)</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">59.83\u00a0\u00b1\u00a01.70**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">58.67\u00a0\u00b1\u00a02.63**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">120.33\u00a0\u00b1\u00a02.63**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">0.638\u00a0\u00b1\u00a00.03**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">0.14\u00a0\u00b1\u00a00.01**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">8.19\u00a0\u00b1\u00a00.02**</td></tr></tbody></table> ##FOOTN## </table-wrap>",
|
| 197 |
-
"<table-wrap id=\"tbl7\" position=\"float\"><label>Table 7</label><caption><title>Phytochemical Screening for Phenolics\nand Flavonoids of Isolated Fractions of the Alcoholic Extract of <italic>C. paniculatum</italic><xref rid=\"t7fn1\" ref-type=\"table-fn\">a</xref></title></caption><table frame=\"hsides\" rules=\"groups\" border=\"0\"><colgroup><col align=\"left\"/><col align=\"left\"/><col align=\"left\"/><col align=\"left\"/><col align=\"left\"/></colgroup><thead><tr><th style=\"border:none;\" align=\"center\">fractions</th><th style=\"border:none;\" align=\"center\">shinoda test</th><th style=\"border:none;\" align=\"center\">ferric\nchloride</th><th style=\"border:none;\" align=\"center\">lead acetate test</th><th style=\"border:none;\" align=\"center\">alkaline reagent test</th></tr></thead><tbody><tr><td style=\"border:none;\" align=\"left\">F1</td><td style=\"border:none;\" align=\"left\">-</td><td style=\"border:none;\" align=\"left\">-</td><td style=\"border:none;\" align=\"left\">-</td><td style=\"border:none;\" align=\"left\">-</td></tr><tr><td style=\"border:none;\" align=\"left\">F 2</td><td style=\"border:none;\" align=\"left\">-</td><td style=\"border:none;\" align=\"left\">-</td><td style=\"border:none;\" align=\"left\">-</td><td style=\"border:none;\" align=\"left\">-</td></tr><tr><td style=\"border:none;\" align=\"left\">F 3</td><td style=\"border:none;\" align=\"left\">-</td><td style=\"border:none;\" align=\"left\">-</td><td style=\"border:none;\" align=\"left\">-</td><td style=\"border:none;\" align=\"left\">-</td></tr><tr><td style=\"border:none;\" align=\"left\">F 4</td><td style=\"border:none;\" align=\"left\">-</td><td style=\"border:none;\" align=\"left\">+</td><td style=\"border:none;\" align=\"left\">+</td><td style=\"border:none;\" align=\"left\">-</td></tr><tr><td style=\"border:none;\" align=\"left\">F 5</td><td style=\"border:none;\" align=\"left\">+++</td><td style=\"border:none;\" align=\"left\">++</td><td style=\"border:none;\" align=\"left\">+++</td><td style=\"border:none;\" align=\"left\">+++</td></tr><tr><td style=\"border:none;\" align=\"left\">F\n6</td><td style=\"border:none;\" align=\"left\">-</td><td style=\"border:none;\" align=\"left\">+</td><td style=\"border:none;\" align=\"left\">++</td><td style=\"border:none;\" align=\"left\">+</td></tr><tr><td style=\"border:none;\" align=\"left\">F 7</td><td style=\"border:none;\" align=\"left\">++</td><td style=\"border:none;\" align=\"left\">+</td><td style=\"border:none;\" align=\"left\">+</td><td style=\"border:none;\" align=\"left\">+</td></tr><tr><td style=\"border:none;\" align=\"left\">F 8</td><td style=\"border:none;\" align=\"left\">++</td><td style=\"border:none;\" align=\"left\">++</td><td style=\"border:none;\" align=\"left\">+</td><td style=\"border:none;\" align=\"left\">+</td></tr><tr><td style=\"border:none;\" align=\"left\">F 9</td><td style=\"border:none;\" align=\"left\">+++</td><td style=\"border:none;\" align=\"left\">+++</td><td style=\"border:none;\" align=\"left\">+++</td><td style=\"border:none;\" align=\"left\">+++</td></tr><tr><td style=\"border:none;\" align=\"left\">F 10</td><td style=\"border:none;\" align=\"left\">++</td><td style=\"border:none;\" align=\"left\">+</td><td style=\"border:none;\" align=\"left\">++</td><td style=\"border:none;\" align=\"left\">+</td></tr><tr><td style=\"border:none;\" align=\"left\">F 11</td><td style=\"border:none;\" align=\"left\">+++</td><td style=\"border:none;\" align=\"left\">++</td><td style=\"border:none;\" align=\"left\">++</td><td style=\"border:none;\" align=\"left\">+</td></tr><tr><td style=\"border:none;\" align=\"left\">F 12</td><td style=\"border:none;\" align=\"left\">++</td><td style=\"border:none;\" align=\"left\">+++</td><td style=\"border:none;\" align=\"left\">+++</td><td style=\"border:none;\" align=\"left\">+</td></tr><tr><td style=\"border:none;\" align=\"left\">F 13</td><td style=\"border:none;\" align=\"left\">++</td><td style=\"border:none;\" align=\"left\">++</td><td style=\"border:none;\" align=\"left\">++</td><td style=\"border:none;\" align=\"left\">+</td></tr></tbody></table> ##FOOTN## </table-wrap>",
|
| 198 |
-
"<table-wrap id=\"tbl8\" position=\"float\"><label>Table 8</label><caption><title>Total Phenolic and Flavonoid Contents\nof Fractions Obtained from the Alcoholic Extract of <italic>C. paniculatum</italic></title></caption><table frame=\"hsides\" rules=\"groups\" border=\"0\"><colgroup><col align=\"left\"/><col align=\"char\" char=\"\u00b1\"/><col align=\"char\" char=\"\u00b1\"/></colgroup><thead><tr><th style=\"border:none;\" align=\"center\">column fraction</th><th style=\"border:none;\" align=\"center\" char=\"\u00b1\">total phenolic content (mg\u00a0GAE/g)</th><th style=\"border:none;\" align=\"center\" char=\"\u00b1\">flavonoid content (mg\u00a0QE/g)</th></tr></thead><tbody><tr><td style=\"border:none;\" align=\"left\">F 5</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">284.91\u00a0\u00b1\u00a06.03</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">333.82\u00a0\u00b1\u00a01.39</td></tr><tr><td style=\"border:none;\" align=\"left\">F 6</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">139.66\u00a0\u00b1\u00a01.93</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">198.39\u00a0\u00b1\u00a02.56</td></tr><tr><td style=\"border:none;\" align=\"left\">F 7</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">109.93\u00a0\u00b1\u00a03.48</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">115.02\u00a0\u00b1\u00a01.62</td></tr><tr><td style=\"border:none;\" align=\"left\">F 8</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">99.083\u00a0\u00b1\u00a04.49</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">99.74\u00a0\u00b1\u00a01.25</td></tr><tr><td style=\"border:none;\" align=\"left\"><bold>F 9</bold></td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">378.31<bold>\u00b1</bold><bold>3.15</bold></td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\"><bold>380.33</bold><bold>\u00b1</bold><bold>1.55</bold></td></tr><tr><td style=\"border:none;\" align=\"left\">F 10</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">97.38\u00a0\u00b1\u00a02.18</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">116.70\u00a0\u00b1\u00a01.77</td></tr><tr><td style=\"border:none;\" align=\"left\">F 11</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">138.78\u00a0\u00b1\u00a04.85</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">174.50\u00a0\u00b1\u00a01.604</td></tr><tr><td style=\"border:none;\" align=\"left\">F 12</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">146.40\u00a0\u00b1\u00a00.50</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">178.56\u00a0\u00b1\u00a01.72</td></tr><tr><td style=\"border:none;\" align=\"left\">F 13</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">147.99\u00a0\u00b1\u00a01.06</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">192.52\u00a0\u00b1\u00a01.61</td></tr></tbody></table></table-wrap>",
|
| 199 |
-
"<table-wrap id=\"tbl9\" position=\"float\"><label>Table 9</label><caption><title><italic>In Vitro</italic> Studies\nof Fractions<xref rid=\"t9fn1\" ref-type=\"table-fn\">a</xref></title></caption><table frame=\"hsides\" rules=\"groups\" border=\"0\"><colgroup><col align=\"left\"/><col align=\"char\" char=\"\u00b1\"/><col align=\"char\" char=\"\u00b1\"/><col align=\"char\" char=\"\u00b1\"/><col align=\"char\" char=\"\u00b1\"/></colgroup><thead><tr><th style=\"border:none;\" align=\"center\">groups</th><th style=\"border:none;\" align=\"center\" char=\"\u00b1\">SGOT (IU/L)</th><th style=\"border:none;\" align=\"center\" char=\"\u00b1\">SGPT (IU/L)</th><th style=\"border:none;\" align=\"center\" char=\"\u00b1\">ALP (IU/L)</th><th style=\"border:none;\" align=\"center\" char=\"\u00b1\">ACP (IU/L)</th></tr></thead><tbody><tr><td style=\"border:none;\" align=\"left\">vehicle\ncontrol</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">39.33\u00a0\u00b1\u00a03.512**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">56.00\u00a0\u00b1\u00a02.646**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">95.67\u00a0\u00b1\u00a02.082**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">10.52\u00a0\u00b1\u00a01.572**</td></tr><tr><td style=\"border:none;\" align=\"left\">toxic control</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">191.00\u00a0\u00b1\u00a05.568</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">248.67\u00a0\u00b1\u00a02.082</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">309.00\u00a0\u00b1\u00a06.557</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">45.33\u00a0\u00b1\u00a01.528</td></tr><tr><td style=\"border:none;\" align=\"left\">standard\n(silymarin 50\u00a0mM)</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">42.67\u00a0\u00b1\u00a04.042**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">62.00\u00a0\u00b1\u00a01.000**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">106.67\u00a0\u00b1\u00a02.517**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">12.33\u00a0\u00b1\u00a02.517**</td></tr><tr><td style=\"border:none;\" align=\"left\">CPLE\nextract (100\u00a0\u03bcg/mL)</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">150.00\u00a0\u00b1\u00a02.000**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">210.00\u00a0\u00b1\u00a04.583**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">266.00\u00a0\u00b1\u00a06.557**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">41.67\u00a0\u00b1\u00a01.528**</td></tr><tr><td style=\"border:none;\" align=\"left\">CPLE extract (200\u00a0\u03bcg/mL)</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">128.33\u00a0\u00b1\u00a01.526**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">180.00\u00a0\u00b1\u00a02.000**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">221.33\u00a0\u00b1\u00a03.215**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">36.33\u00a0\u00b1\u00a01.528**</td></tr><tr><td style=\"border:none;\" align=\"left\">CPLE extract (400\u00a0\u03bcg/mL)</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">101.33\u00a0\u00b1\u00a02.517**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">157.33\u00a0\u00b1\u00a04.510**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">181.67\u00a0\u00b1\u00a06.658**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">33.00\u00a0\u00b1\u00a04.000**</td></tr><tr><td style=\"border:none;\" align=\"left\">fraction 5 (25\u00a0\u03bcg/mL)</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">132.00\u00a0\u00b1\u00a02.000**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">156.33\u00a0\u00b1\u00a04.042**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">172.67\u00a0\u00b1\u00a02.516**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">40.67\u00a0\u00b1\u00a02.082**</td></tr><tr><td style=\"border:none;\" align=\"left\">fraction 5 (50\u00a0\u03bcg/mL)</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">124.00\u00a0\u00b1\u00a03.606**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">142.67\u00a0\u00b1\u00a03.055**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">161.33\u00a0\u00b1\u00a03.215**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">31.67\u00a0\u00b1\u00a00.577**</td></tr><tr><td style=\"border:none;\" align=\"left\">fraction 5 (100\u00a0\u03bcg/mL)</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">96.33\u00a0\u00b1\u00a06.110**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">132.33\u00a0\u00b1\u00a05.860**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">145.67\u00a0\u00b1\u00a04.042**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">30.00\u00a0\u00b1\u00a05.000**</td></tr><tr><td style=\"border:none;\" align=\"left\">fraction 9 (25\u00a0\u03bcg/mL)</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">95.67\u00a0\u00b1\u00a03.055**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">124.00\u00a0\u00b1\u00a02.646**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">147.00\u00a0\u00b1\u00a06.245**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">27.33\u00a0\u00b1\u00a01.528**</td></tr><tr><td style=\"border:none;\" align=\"left\">fraction 9 (50\u00a0\u03bcg/mL)</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">70.33\u00a0\u00b1\u00a01.528**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">110.67\u00a0\u00b1\u00a02.082**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">132.33\u00a0\u00b1\u00a02.517**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">26.00\u00a0\u00b1\u00a02.000**</td></tr><tr><td style=\"border:none;\" align=\"left\">fraction 9 (100\u00a0\u03bcg/mL)</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">56.67\u00a0\u00b1\u00a04.726**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">83.0\u00a0\u00b1\u00a04.000**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">118.00\u00a0\u00b1\u00a02.646**</td><td style=\"border:none;\" align=\"char\" char=\"\u00b1\">20.00\u00a0\u00b1\u00a01.000**</td></tr></tbody></table> ##FOOTN## </table-wrap>"
|
| 200 |
],
|
| 201 |
"formula": [
|
| 202 |
"<disp-formula id=\"ueq1\"> ##GRAPH## </disp-formula>"
|
| 203 |
],
|
| 204 |
"box": [
|
| 205 |
"EXAMPLE FROM ANOTHER ARTICLE",
|
| 206 |
-
"<boxed-text id=\"BX1\" position=\"float\" orientation=\"portrait\"><caption><title>Key messages</title></caption><list list-type=\"bullet\"
|
| 207 |
],
|
| 208 |
"code": [
|
| 209 |
"EXAMPLE FROM ANOTHER ARTICLE",
|
| 210 |
-
"<code xml:space=\"preserve\" position=\"float\" orientation=\"portrait\">\n<monospace>\n\nLupe.dat$w <\u2013 ifelse(Lupe.dat$case_
|
| 211 |
-
"<code xml:space=\"preserve\" position=\"float\" orientation=\"portrait\">\n<monospace>\n\nLupe.dat <\u2010 within(Lupe.dat,\n\n\n landuseC1
|
| 212 |
-
"<code xml:space=\"preserve\" position=\"float\" orientation=\"portrait\">\n<monospace>\n\nLupe.dat <\u2010 within(Lupe.dat, landuseC <\u2010
|
| 213 |
],
|
| 214 |
"quote": [
|
| 215 |
"EXAMPLE FROM ANOTHER ARTICLE",
|
| 216 |
-
"<disp-quote><p id=\"Par20\">I constantly feel like I am fighting some system or individual to get my medical needs met
|
| 217 |
-
"<disp-quote><p id=\"Par25\">Generally, there is a neurological exam performed, but it is subjective and by no means inclusive
|
| 218 |
-
"<disp-quote><p id=\"Par31\">Every day you wake up and do an inventory of what body parts are functioning properly, first. Then, you decide if you are going to lie to yourself and others and say, \u201cI\u2019m fine,\u201d when asked how you are doing because you know it is easier.</p><p id=\"Par32\">\u2014Keisha Currie</p></disp-quote>",
|
| 219 |
-
"<disp-quote><p id=\"Par34\">As an administrator of a 35,000-member online group of people living with MS, I often hear, \u201cWe are not taken seriously!\u201d, \u201cI am treated as a drug seeker,\u201d and \u201cThe doctor doesn\u2019t believe me because they can\u2019t see how this impacts me because I look good during the visit.\u201d</p><p id=\"Par35\">\u2014Cherie Binns</p></disp-quote>",
|
| 220 |
-
"<disp-quote><p id=\"Par38\">Often, African Americans have religious views and will reply, \u201cJust pray about it!\u2019\u201d to imply that God will simply take my MS away. Thankfully, I had developed my own views about this shortly after diagnosis or it would have been more isolating.</p><p id=\"Par39\">\u2014Keisha Currie</p></disp-quote>",
|
| 221 |
-
"<disp-quote><p id=\"Par42\">I feel that HCPs can have honest conversations with patients about how their MS is presenting, how management strategies can be beneficial, and long-term planning.</p><p id=\"Par43\">\u2014Keisha Currie</p></disp-quote>"
|
| 222 |
],
|
| 223 |
"chem": [
|
| 224 |
"EXAMPLE FROM ANOTHER ARTICLE",
|
| 225 |
"<chem-struct-wrap id=\"open202000358-disp-0001\" position=\"float\" orientation=\"portrait\"><chem-struct> ##GRAPH## </chem-struct></chem-struct-wrap>",
|
| 226 |
-
"<chem-struct-wrap id=\"open202000358-disp-0002\" position=\"float\" orientation=\"portrait\"><chem-struct> ##GRAPH## </chem-struct></chem-struct-wrap>"
|
| 227 |
-
"<chem-struct-wrap id=\"open202000358-disp-0003\" position=\"float\" orientation=\"portrait\"><chem-struct> ##GRAPH## </chem-struct></chem-struct-wrap>",
|
| 228 |
-
"<chem-struct-wrap id=\"open202000358-disp-0004\" position=\"float\" orientation=\"portrait\"><chem-struct> ##GRAPH## </chem-struct></chem-struct-wrap>"
|
| 229 |
],
|
| 230 |
"supplementary": [
|
| 231 |
"<supplementary-material content-type=\"local-data\" id=\"sifile1\"> ##MEDIA## </supplementary-material>"
|
|
@@ -233,19 +181,12 @@ a corpus of pre-annotated text for other tasks (e.g. figure caption to graphic,
|
|
| 233 |
"footnote": [
|
| 234 |
"<table-wrap-foot><fn id=\"t1fn1\"><label>a</label><p>+++: highly present, ++: moderately\npresent, +: low, and -: absent.</p></fn></table-wrap-foot>",
|
| 235 |
"<table-wrap-foot><fn id=\"t3fn1\"><label>a</label><p><italic>p</italic> < 0.01, as\ncompared with the standard group.</p></fn></table-wrap-foot>",
|
| 236 |
-
"<table-wrap-foot><fn id=\"t4fn1\"><label>a</label><p><italic>p</italic> < 0.01, as\ncompared with the standard group.</p></fn></table-wrap-foot>"
|
| 237 |
-
|
| 238 |
-
"<table-wrap-foot><fn id=\"t6fn1\"><label>a</label><p>Values\nare expressed as mean \u00b1\nSEM of six rats in each group. **<italic>p</italic> < 0.05, as\ncompared with the toxic control group.</p></fn><fn id=\"t6fn2\"><label>b</label><p>CPFA: <italic>C. paniculatum</italic> flower\nalcoholic extract, SGOT: serum glutamate oxaloacetate transferase,\nSGPT: serum glutamate pyruvate transferase, and ALP: alkaline phosphatase.</p></fn></table-wrap-foot>",
|
| 239 |
-
"<table-wrap-foot><fn id=\"t7fn1\"><label>a</label><p>+++: highly present, ++: moderately\npresent, +: low, -: absent, and F represents fractions.</p></fn></table-wrap-foot>",
|
| 240 |
-
"<table-wrap-foot><fn id=\"t9fn1\"><label>a</label><p>The values are represented as mean\n\u00b1 S.D (<italic>n</italic> = 3), **<italic>P</italic> < 0.05,\nas compared with the toxic control group.</p></fn></table-wrap-foot>"
|
| 241 |
-
],
|
| 242 |
"graphic": [
|
| 243 |
"<graphic xlink:href=\"ao1c03722_0006\" id=\"ab-tgr1\"/>",
|
| 244 |
"<graphic xlink:href=\"ao1c03722_0002\" id=\"gr1\" position=\"float\"/>",
|
| 245 |
-
"<graphic xlink:href=\"ao1c03722_0003\" id=\"gr2\" position=\"float\"/>"
|
| 246 |
-
"<graphic xlink:href=\"ao1c03722_0004\" id=\"gr3\" position=\"float\"/>",
|
| 247 |
-
"<graphic xlink:href=\"ao1c03722_0005\" id=\"gr4\" position=\"float\"/>",
|
| 248 |
-
"<graphic xlink:href=\"ao1c03722_m001\" position=\"anchor\"/>"
|
| 249 |
],
|
| 250 |
"media": [
|
| 251 |
"<media xlink:href=\"ao1c03722_si_001.pdf\"><caption><p>ao1c03722_si_001.pdf</p></caption></media>"
|
|
@@ -259,17 +200,7 @@ a corpus of pre-annotated text for other tasks (e.g. figure caption to graphic,
|
|
| 259 |
"CPFA",
|
| 260 |
"CPFW",
|
| 261 |
"DPPH",
|
| 262 |
-
"ABTS"
|
| 263 |
-
"NO",
|
| 264 |
-
"GAE",
|
| 265 |
-
"QE",
|
| 266 |
-
"SGOT",
|
| 267 |
-
"SGPT",
|
| 268 |
-
"ALP",
|
| 269 |
-
"\u03b3-GT",
|
| 270 |
-
"CMC",
|
| 271 |
-
"b.w.",
|
| 272 |
-
"s.c"
|
| 273 |
],
|
| 274 |
"definition": [
|
| 275 |
"Clerodendrum paniculatum flower petroleum ether extract",
|
|
@@ -278,17 +209,7 @@ a corpus of pre-annotated text for other tasks (e.g. figure caption to graphic,
|
|
| 278 |
"Clerodendrum paniculatum flower\nalcohol extract",
|
| 279 |
"Clerodendrum paniculatum flower water\nextract",
|
| 280 |
"2,2-diphenyl-2-picryl\nhydrazyl",
|
| 281 |
-
"2,2-azino-bis\n(3-ethyl benzothiazoline-6-sufonic\nacid)"
|
| 282 |
-
"nitric\noxide",
|
| 283 |
-
"gallic\nacid equivalent",
|
| 284 |
-
"quercetin equivalent",
|
| 285 |
-
"serum glutamate oxaloacetate transaminase",
|
| 286 |
-
"serum glutamate pyruvate transaminase",
|
| 287 |
-
"alkaline phospahtase",
|
| 288 |
-
"gamma glutamyl\ntransferase",
|
| 289 |
-
"carboxy methyl cellulose",
|
| 290 |
-
"body weight",
|
| 291 |
-
"subcutaneous"
|
| 292 |
]
|
| 293 |
},
|
| 294 |
"references": {
|
|
@@ -340,12 +261,7 @@ a corpus of pre-annotated text for other tasks (e.g. figure caption to graphic,
|
|
| 340 |
1,
|
| 341 |
2,
|
| 342 |
3,
|
| 343 |
-
4
|
| 344 |
-
5,
|
| 345 |
-
6,
|
| 346 |
-
7,
|
| 347 |
-
7,
|
| 348 |
-
8
|
| 349 |
],
|
| 350 |
"formula_ref": [],
|
| 351 |
"box_ref": [],
|
|
@@ -420,13 +336,7 @@ a corpus of pre-annotated text for other tasks (e.g. figure caption to graphic,
|
|
| 420 |
"Table 1",
|
| 421 |
"Table 2",
|
| 422 |
"Table 3",
|
| 423 |
-
"Table 4"
|
| 424 |
-
"Table 5",
|
| 425 |
-
"Table 6",
|
| 426 |
-
"Table 7",
|
| 427 |
-
"Table 8",
|
| 428 |
-
"Table 8",
|
| 429 |
-
"Table 9"
|
| 430 |
],
|
| 431 |
"formula_ref": [],
|
| 432 |
"box_ref": [],
|
|
@@ -463,53 +373,52 @@ a corpus of pre-annotated text for other tasks (e.g. figure caption to graphic,
|
|
| 463 |
```
|
| 464 |
|
| 465 |
### Data Fields
|
| 466 |
-
|
| 467 |
-
"accession_id": The PMC ID of the article
|
| 468 |
-
"pmid": The PubMed ID of the article
|
| 469 |
-
"introduction": List of <title> and <p> elements in <body>, sharing their root with a <title> containing "introduction" or "background".
|
| 470 |
-
"methods": Same as introduction with "method" keyword.
|
| 471 |
-
"results": Same as introduction with "result" keyword.
|
| 472 |
-
"discussion": Same as introduction with "discussion" keyword.
|
| 473 |
-
"conclusion": Same as introduction with "conclusion" keyword.
|
| 474 |
-
"front": List of <title> and <p> elements in <front> after everything else has been searched.
|
| 475 |
-
"body": List of <title> and <p> elements in <body> after everything else has been searched.
|
| 476 |
-
"back": List of <title> and <p> elements in <back> after everything else has been searched.
|
| 477 |
-
"figure": List of <fig> elements of the article.
|
| 478 |
-
"table": List of <table-wrap> and <array> elements of the article.
|
| 479 |
-
"formula": List of <disp-formula> and <inline-formula> elements of the article.
|
| 480 |
-
"box": List of <boxed-text> elements of the article.
|
| 481 |
-
"code": List of <code> elements of the article.
|
| 482 |
-
"quote": List of <disp-quote> and <speech> elements of the article.
|
| 483 |
-
"chem": List of <chem-struct-wrap> elements of the article.
|
| 484 |
-
"supplementary": List of <supplementary-material> and <inline-supplementary-material> elements of the article.
|
| 485 |
-
"footnote": List of <fn-group> and <table-wrap-foot> elements of the article.
|
| 486 |
-
"graphic": List of <graphic> and <inline-graphic> elements of the article.
|
| 487 |
-
"media": List of <media> and <inline-media> elements of the article.
|
| 488 |
-
|
| 489 |
-
"references": Lists of references in the order found in the corresponding categories
|
| 490 |
-
"pmid_ref": PMIDs of other articles. In text, replaced by " ##REF## "
|
| 491 |
-
"unknown_pub_ref": 0-indexed idx of the article in "unknown_pub". In text, replaced by " ##UREF## "
|
| 492 |
-
"figure_ref": 0-indexed idx of the figures in "figure" In text, replaced by " ##FIG## "
|
| 493 |
-
"table_ref": 0-indexed idx of the tables in "table" In text, replaced by " ##TAB## "
|
| 494 |
-
"formula_ref": 0-indexed idx of the formulas in "formula" In text, replaced by " ##FORMU## "
|
| 495 |
-
"box_ref": 0-indexed idx of the box in "box" In text, replaced by " ##BOX## "
|
| 496 |
-
"code_ref": 0-indexed idx of the code in "code" In text, replaced by " ##CODE## "
|
| 497 |
-
"quote_ref": 0-indexed idx of the quote in "quote" In text, replaced by " ##QUOTE## "
|
| 498 |
-
"chem_ref": 0-indexed idx of the chemical in "chem" In text, replaced by " ##CHEM## "
|
| 499 |
-
"supplementary_ref": 0-indexed idx of the figure in "supplementary" In text, replaced by " ##SUPPL## "
|
| 500 |
-
"footnote_ref": 0-indexed idx of the footnote in "footnote" In text, replaced by " ##FOOTN## "
|
| 501 |
-
"graphic_ref": 0-indexed idx of the graphics in "graphics" In text, replaced by " ##GRAPH## "
|
| 502 |
-
"media_ref": 0-indexed idx of the medias in "medias" In text, replaced by " ##MEDIA## "
|
| 503 |
-
"references_text": For each reference in "references", the corresponding text that the reference keywords replaced.
|
| 504 |
-
"glossary": Glossary if found in the XML
|
| 505 |
-
"unknown_references": JSON of a dictionnary of each "tag":"text" for the reference that did not indicate a PMID
|
| 506 |
-
"n_references": Total number of references and unknown references
|
| 507 |
-
"license": The licence of the article
|
| 508 |
-
"retracted": If the article was retracted or not
|
| 509 |
-
"last_updated": Last update of the article
|
| 510 |
-
"citation": Citation of the article
|
| 511 |
-
"package_file": path to the folder containing the graphics and media files of the article
|
| 512 |
-
```
|
| 513 |
|
| 514 |
### Data Splits
|
| 515 |
|
|
|
|
| 91 |
"pmid": "34661004",
|
| 92 |
"introduction": [
|
| 93 |
"<title>Introduction</title>",
|
| 94 |
+
"<p>Medicinal plants are\nknown to possess several primary and secondary\nmetabolites. The secondary metabolites ...",
|
| 95 |
+
"<p>Genus <italic>Clerodendrum</italic> belonging to\nfamily Verbenaceae or Lamiaceae has more than 500 species. ..."
|
| 96 |
],
|
| 97 |
"methods": [
|
| 98 |
"<title>DPPH Method</title>",
|
| 99 |
+
"<p>The most effective and popular method of\nantioxidant evaluation is the DPPH radical scavenging method. Better..."
|
| 100 |
],
|
| 101 |
"results": [
|
| 102 |
"<title>Results</title>",
|
| 103 |
+
"<p>The phytochemical screening of the flower extract indicated the\npresence of carbohydrates, tannins, phenolics, ...",
|
| 104 |
+
"<p>The total phenolic content,<sup> ##REF## </sup> as quantified\nby Folin-Ciocalteu\u2019s method, indicates the highest ...",
|
| 105 |
+
"<p>Antioxidant activity of the extracts was evaluated by four different\nmethods.<sup> ##REF## </sup> Antioxidants have a high...",
|
| 106 |
+
"<p>DPPH is widely used as an evaluation technique due\nto its ease\nof reaction. In the ABTS assay method, radical scavenging ...",
|
| 107 |
+
"<p>Nitric oxide radical scavenging activity results of\nthe extract\nwere evaluated by comparing with standard gallic acid. Nitric ...",
|
| 108 |
+
"<p>Reducing power ability of the extracts was determined\nusing potassium\nferricyanide. The ability of the extract to reduce potassium ...",
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 109 |
],
|
| 110 |
"discussion": [
|
| 111 |
"<title>Discussion</title>",
|
| 112 |
+
"<p>The\nliver, the major metabolic organ of our body, may have toxicity\ndue to various drugs like alcohol, anabolic steroids,...",
|
| 113 |
+
"<p>Internal antioxidant deficiency can be overcome by\nsupplementing\nwith external sources. Since polyphenolics are known to have ..."
|
| 114 |
],
|
| 115 |
"conclusion": [
|
| 116 |
"<title>Conclusions</title>",
|
| 117 |
+
"<p>The implication on the\npharmacological properties from the flower\nextract ..."
|
| 118 |
],
|
| 119 |
"front": [
|
| 120 |
"<p content-type=\"toc-graphic\"> ##GRAPH## </p>",
|
| 121 |
+
"<p>The aim of the presented\nwork involves the isolation, characterization,\nand evaluation of hepatoprotective potential of ...",
|
| 122 |
],
|
| 123 |
"body": [
|
| 124 |
"<title>Experimental\nSection</title>",
|
| 125 |
"<title>Chemicals and Reagents</title>",
|
| 126 |
+
"<p>The chemicals and reagents used\nfor the experiments carried out for the present investigation were\npurchased from ...",
|
| 127 |
"<title>Plant Collection</title>",
|
| 128 |
+
"<p><italic>C. paniculatum</italic> flowers were collected from Malappuram, Kerala during August to\nOctober. ...",
|
| 129 |
"<title>Preparation of Plant Extracts</title>",
|
| 130 |
+
"<p>The flowers weighing\n\u223c300 g were collected and dried under shade. Successively,\nsolvent extraction was carried out using ...",
|
| 131 |
"<title>Preliminary Phytochemical Screening</title>",
|
| 132 |
+
"<p>Preliminary qualitative\nanalysis was carried out for detecting the presence of various classes\nof compounds like alkaloids, ...",],
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 133 |
"back": [
|
| 134 |
"<title>Supporting Information Available</title>",
|
| 135 |
+
"<p>The Supporting Information is\navailable free of charge at <ext-link xmlns:xlink=\"http://www.w3.org/1999/xlink\" ...",
|
| 136 |
"<title>Supplementary Material</title>",
|
| 137 |
"<p>This research\ndid not receive any specific grant from funding agencies in the public,\ncommercial, or not-for-profit sectors.</p>",
|
| 138 |
"<p>The authors declare no\ncompeting financial interest.</p>",
|
| 139 |
"<title>Acknowledgments</title>",
|
| 140 |
+
"<p>The authors would like to express their sincere\nthanks to the Management of Vellore Institute of Technology, Vellore\nand ..."
|
| 141 |
],
|
| 142 |
"figure": [
|
| 143 |
+
"<fig id=\"fig1\" position=\"float\"><label>Figure 1</label><caption><p>Determination\nof reducing power for various solvent...",
|
| 144 |
+
"<fig id=\"fig2\" position=\"float\"><label>Figure 2</label><caption><p>Photographs of hematoxylin/eosin-stained liver sections....",
|
| 145 |
"<fig id=\"fig3\" position=\"float\"><label>Figure 3</label><caption><p>GC\u2013MS chromatogram of fraction 9.</p></caption> ##GRAPH## </fig>",
|
| 146 |
"<fig id=\"fig4\" position=\"float\"><label>Figure 4</label><caption><p>HPTLC\nplates observed under (a) normal light and (b) 254 and (c)\n366 nm.</p></caption> ##GRAPH## </fig>"
|
| 147 |
],
|
| 148 |
"table": [
|
| 149 |
+
"<table-wrap id=\"tbl1\" position=\"float\"><label>Table 1</label><caption><title>Phytochemical Screening for the Flower\nExtract ...",
|
| 150 |
+
"<table-wrap id=\"tbl2\" position=\"float\"><label>Table 2</label><caption><title>Quantification of Total Phenolics\nand Flavonoids in ...",
|
| 151 |
+
"<table-wrap id=\"tbl3\" position=\"float\"><label>Table 3</label><caption><title>Antioxidant\nPotential, as Determined\nby DPPH Assay with the...",
|
| 152 |
+
"<table-wrap id=\"tbl4\" position=\"float\"><label>Table 4</label><caption><title>Antioxidant Activity, as Evaluated\nby ABTS Assay with the Alcoholic...",
|
| 153 |
+
"<table-wrap id=\"tbl5\" position=\"float\"><label>Table 5</label><caption><title>Antioxidant Activity, as Determined\nby Nitric Oxide Radical Scavenging Assay...",
|
|
|
|
|
|
|
|
|
|
|
|
|
| 154 |
],
|
| 155 |
"formula": [
|
| 156 |
"<disp-formula id=\"ueq1\"> ##GRAPH## </disp-formula>"
|
| 157 |
],
|
| 158 |
"box": [
|
| 159 |
"EXAMPLE FROM ANOTHER ARTICLE",
|
| 160 |
+
"<boxed-text id=\"BX1\" position=\"float\" orientation=\"portrait\"><caption><title>Key messages</title></caption><list list-type=\"bullet\">...",
|
| 161 |
],
|
| 162 |
"code": [
|
| 163 |
"EXAMPLE FROM ANOTHER ARTICLE",
|
| 164 |
+
"<code xml:space=\"preserve\" position=\"float\" orientation=\"portrait\">\n<monospace>\n\nLupe.dat$w <\u2013 ifelse(Lupe.dat$case_...",
|
| 165 |
+
"<code xml:space=\"preserve\" position=\"float\" orientation=\"portrait\">\n<monospace>\n\nLupe.dat <\u2010 within(Lupe.dat,\n\n\n landuseC1...",
|
| 166 |
+
"<code xml:space=\"preserve\" position=\"float\" orientation=\"portrait\">\n<monospace>\n\nLupe.dat <\u2010 within(Lupe.dat, landuseC <\u2010...",
|
| 167 |
],
|
| 168 |
"quote": [
|
| 169 |
"EXAMPLE FROM ANOTHER ARTICLE",
|
| 170 |
+
"<disp-quote><p id=\"Par20\">I constantly feel like I am fighting some system or individual to get my medical needs met...",
|
| 171 |
+
"<disp-quote><p id=\"Par25\">Generally, there is a neurological exam performed, but it is subjective and by no means inclusive ...",
|
|
|
|
|
|
|
|
|
|
|
|
|
| 172 |
],
|
| 173 |
"chem": [
|
| 174 |
"EXAMPLE FROM ANOTHER ARTICLE",
|
| 175 |
"<chem-struct-wrap id=\"open202000358-disp-0001\" position=\"float\" orientation=\"portrait\"><chem-struct> ##GRAPH## </chem-struct></chem-struct-wrap>",
|
| 176 |
+
"<chem-struct-wrap id=\"open202000358-disp-0002\" position=\"float\" orientation=\"portrait\"><chem-struct> ##GRAPH## </chem-struct></chem-struct-wrap>"
|
|
|
|
|
|
|
| 177 |
],
|
| 178 |
"supplementary": [
|
| 179 |
"<supplementary-material content-type=\"local-data\" id=\"sifile1\"> ##MEDIA## </supplementary-material>"
|
|
|
|
| 181 |
"footnote": [
|
| 182 |
"<table-wrap-foot><fn id=\"t1fn1\"><label>a</label><p>+++: highly present, ++: moderately\npresent, +: low, and -: absent.</p></fn></table-wrap-foot>",
|
| 183 |
"<table-wrap-foot><fn id=\"t3fn1\"><label>a</label><p><italic>p</italic> < 0.01, as\ncompared with the standard group.</p></fn></table-wrap-foot>",
|
| 184 |
+
"<table-wrap-foot><fn id=\"t4fn1\"><label>a</label><p><italic>p</italic> < 0.01, as\ncompared with the standard group.</p></fn></table-wrap-foot>"
|
| 185 |
+
],
|
|
|
|
|
|
|
|
|
|
|
|
|
| 186 |
"graphic": [
|
| 187 |
"<graphic xlink:href=\"ao1c03722_0006\" id=\"ab-tgr1\"/>",
|
| 188 |
"<graphic xlink:href=\"ao1c03722_0002\" id=\"gr1\" position=\"float\"/>",
|
| 189 |
+
"<graphic xlink:href=\"ao1c03722_0003\" id=\"gr2\" position=\"float\"/>"
|
|
|
|
|
|
|
|
|
|
| 190 |
],
|
| 191 |
"media": [
|
| 192 |
"<media xlink:href=\"ao1c03722_si_001.pdf\"><caption><p>ao1c03722_si_001.pdf</p></caption></media>"
|
|
|
|
| 200 |
"CPFA",
|
| 201 |
"CPFW",
|
| 202 |
"DPPH",
|
| 203 |
+
"ABTS"
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 204 |
],
|
| 205 |
"definition": [
|
| 206 |
"Clerodendrum paniculatum flower petroleum ether extract",
|
|
|
|
| 209 |
"Clerodendrum paniculatum flower\nalcohol extract",
|
| 210 |
"Clerodendrum paniculatum flower water\nextract",
|
| 211 |
"2,2-diphenyl-2-picryl\nhydrazyl",
|
| 212 |
+
"2,2-azino-bis\n(3-ethyl benzothiazoline-6-sufonic\nacid)"
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 213 |
]
|
| 214 |
},
|
| 215 |
"references": {
|
|
|
|
| 261 |
1,
|
| 262 |
2,
|
| 263 |
3,
|
| 264 |
+
4
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 265 |
],
|
| 266 |
"formula_ref": [],
|
| 267 |
"box_ref": [],
|
|
|
|
| 336 |
"Table 1",
|
| 337 |
"Table 2",
|
| 338 |
"Table 3",
|
| 339 |
+
"Table 4"
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 340 |
],
|
| 341 |
"formula_ref": [],
|
| 342 |
"box_ref": [],
|
|
|
|
| 373 |
```
|
| 374 |
|
| 375 |
### Data Fields
|
| 376 |
+
|
| 377 |
+
- "accession_id": The PMC ID of the article
|
| 378 |
+
- "pmid": The PubMed ID of the article
|
| 379 |
+
- "introduction": List of <title> and <p> elements in <body>, sharing their root with a <title> containing "introduction" or "background".
|
| 380 |
+
- "methods": Same as introduction with "method" keyword.
|
| 381 |
+
- "results": Same as introduction with "result" keyword.
|
| 382 |
+
- "discussion": Same as introduction with "discussion" keyword.
|
| 383 |
+
- "conclusion": Same as introduction with "conclusion" keyword.
|
| 384 |
+
- "front": List of <title> and <p> elements in <front> after everything else has been searched.
|
| 385 |
+
- "body": List of <title> and <p> elements in <body> after everything else has been searched.
|
| 386 |
+
- "back": List of <title> and <p> elements in <back> after everything else has been searched.
|
| 387 |
+
- "figure": List of <fig> elements of the article.
|
| 388 |
+
- "table": List of <table-wrap> and <array> elements of the article.
|
| 389 |
+
- "formula": List of <disp-formula> and <inline-formula> elements of the article.
|
| 390 |
+
- "box": List of <boxed-text> elements of the article.
|
| 391 |
+
- "code": List of <code> elements of the article.
|
| 392 |
+
- "quote": List of <disp-quote> and <speech> elements of the article.
|
| 393 |
+
- "chem": List of <chem-struct-wrap> elements of the article.
|
| 394 |
+
- "supplementary": List of <supplementary-material> and <inline-supplementary-material> elements of the article.
|
| 395 |
+
- "footnote": List of <fn-group> and <table-wrap-foot> elements of the article.
|
| 396 |
+
- "graphic": List of <graphic> and <inline-graphic> elements of the article.
|
| 397 |
+
- "media": List of <media> and <inline-media> elements of the article.
|
| 398 |
+
|
| 399 |
+
- "references": Lists of references in the order found in the corresponding categories
|
| 400 |
+
- "pmid_ref": PMIDs of other articles. In text, replaced by " ##REF## "
|
| 401 |
+
- "unknown_pub_ref": 0-indexed idx of the article in "unknown_pub". In text, replaced by " ##UREF## "
|
| 402 |
+
- "figure_ref": 0-indexed idx of the figures in "figure" In text, replaced by " ##FIG## "
|
| 403 |
+
- "table_ref": 0-indexed idx of the tables in "table" In text, replaced by " ##TAB## "
|
| 404 |
+
- "formula_ref": 0-indexed idx of the formulas in "formula" In text, replaced by " ##FORMU## "
|
| 405 |
+
- "box_ref": 0-indexed idx of the box in "box" In text, replaced by " ##BOX## "
|
| 406 |
+
- "code_ref": 0-indexed idx of the code in "code" In text, replaced by " ##CODE## "
|
| 407 |
+
- "quote_ref": 0-indexed idx of the quote in "quote" In text, replaced by " ##QUOTE## "
|
| 408 |
+
- "chem_ref": 0-indexed idx of the chemical in "chem" In text, replaced by " ##CHEM## "
|
| 409 |
+
- "supplementary_ref": 0-indexed idx of the figure in "supplementary" In text, replaced by " ##SUPPL## "
|
| 410 |
+
- "footnote_ref": 0-indexed idx of the footnote in "footnote" In text, replaced by " ##FOOTN## "
|
| 411 |
+
- "graphic_ref": 0-indexed idx of the graphics in "graphics" In text, replaced by " ##GRAPH## "
|
| 412 |
+
- "media_ref": 0-indexed idx of the medias in "medias" In text, replaced by " ##MEDIA## "
|
| 413 |
+
- "references_text": For each reference in "references", the corresponding text that the reference keywords replaced.
|
| 414 |
+
- "glossary": Glossary if found in the XML
|
| 415 |
+
- "unknown_references": JSON of a dictionnary of each "tag":"text" for the reference that did not indicate a PMID
|
| 416 |
+
- "n_references": Total number of references and unknown references
|
| 417 |
+
- "license": The licence of the article
|
| 418 |
+
- "retracted": If the article was retracted or not
|
| 419 |
+
- "last_updated": Last update of the article
|
| 420 |
+
- "citation": Citation of the article
|
| 421 |
+
- "package_file": path to the folder containing the graphics and media files of the article
|
|
|
|
| 422 |
|
| 423 |
### Data Splits
|
| 424 |
|