Shekswess/llama3_medquad_instruct_dataset huggingface dataset:
Question: What is (are) Cough ?
Answer: A cough is a natural reflex that protects your lungs. Coughing helps clear your airways of lung irritants, such as smoke and mucus (a slimy substance). This helps prevent infections. A cough also can be a symptom of a medical problem.
                
Prolonged coughing can cause unpleasant side effects, such as chest pain, exhaustion, light-headedness, and loss of bladder control. Coughing also can interfere with sleep, socializing, and work.
                
Overview
                
Coughing occurs when the nerve endings in your airways become irritated. The airways are tubes that carry air into and out of your lungs. Certain substances (such as smoke and pollen), medical conditions, and medicines can irritate these nerve endings.
                
A cough can be acute, subacute, or chronic, depending on how long it lasts.
                
An acute cough lasts less than 3 weeks. Common causes of an acute cough are a common cold or other upper respiratory (RES-pi-rah-tor-e) infections. Examples of other upper respiratory infections include the flu, pneumonia (nu-MO-ne-ah), and whooping cough.
                
A subacute cough lasts 3 to 8 weeks. This type of cough remains even after a cold or other respiratory infection is over.
                
A chronic cough lasts more than 8 weeks. Common causes of a chronic cough are upper airway cough syndrome (UACS); asthma; and gastroesophageal (GAS-tro-eh-so-fa-JE-al) reflux disease, or GERD.
                
"UACS" is a term used to describe conditions that inflame the upper airways and cause a cough. Examples include sinus infections and allergies. These conditions can cause mucus to run down your throat from the back of your nose. This is called postnasal drip.
                
Asthma is a long-term lung disease that inflames and narrows the airways. GERD occurs if acid from your stomach backs up into your throat.
                
Outlook
                
The best way to treat a cough is to treat its cause. For example, asthma is treated with medicines that open the airways.
                
Your doctor may recommend cough medicine if the cause of your cough is unknown and the cough causes a lot of discomfort. Cough medicines may harm children. If your child has a cough, talk with his or her doctor about how to treat it.
Question: Who is at risk for Cough? ?
Answer: People at risk for cough include those who:
                
Are exposed to things that irritate their airways (called irritants) or things that they're allergic to (called allergens). Examples of irritants are cigarette smoke, air pollution, paint fumes, and scented products. Examples of allergens are dust, animal dander, mold, and pollens from trees, grasses, and flowers.
                
Have certain conditions that irritate the lungs, such as asthma, sinus infections, colds, or gastroesophageal reflux disease.
                
Smoke. Smoking can irritate your lungs and cause coughing. Smoking and/or exposure to secondhand smoke also can lead to medical conditions that can cause a cough.
                
Take certain medicines, such as ACE inhibitors and beta blockers. ACE inhibitors are used to treat high blood pressure (HBP). Beta blockers are used to treat HBP, migraine headaches, and glaucoma.
                
Women are more likely than men to develop a chronic cough. For more information about the substances and conditions that put you at risk for cough, go to "What Causes Cough?"
Question: What are the symptoms of Cough ?
Answer: When you cough, mucus (a slimy substance) may come up. Coughing helps clear the mucus in your airways from a cold, bronchitis, or other condition. Rarely, people cough up blood. If this happens, you should call your doctor right away.
                
A cough may be a symptom of a medical condition. Thus, it may occur with other signs and symptoms of that condition. For example, if you have a cold, you may have a runny or stuffy nose. If you have gastroesophageal reflux disease, you may have a sour taste in your mouth.
                
A chronic cough can make you feel tired because you use a lot of energy to cough. It also can prevent you from sleeping well and interfere with work and socializing. A chronic cough also can cause headaches, chest pain, loss of bladder control, sweating, and, rarely, fractured ribs.
Question: How to diagnose Cough ?
Answer: Your doctor will diagnose the cause of your cough based on your medical history, a physical exam, and test results.
                
Medical History
                
Your doctor will likely ask questions about your cough. He or she may ask how long you've had it, whether you're coughing anything up (such as mucus, a slimy substance), and how much you cough.
                
Your doctor also may ask:
                
About your medical history, including whether you have allergies, asthma, or other medical conditions.
                
Whether you have heartburn or a sour taste in your mouth. These may be signs of gastroesophageal reflux disease (GERD).
                
Whether you've recently had a cold or the flu.
                
Whether you smoke or spend time around others who smoke.
                
Whether you've been around air pollution, a lot of dust, or fumes.
                
Physical Exam
                
To check for signs of problems related to cough, your doctor will use a stethoscope to listen to your lungs. He or she will listen for wheezing (a whistling or squeaky sound when you breathe) or other abnormal sounds.
                
Diagnostic Tests
                
Your doctor may recommend tests based on the results of your medical history and physical exam. For example, if you have symptoms of GERD, your doctor may recommend a pH probe. This test measures the acid level of the fluid in your throat.
                
Other tests may include:
                
An exam of the mucus from your nose or throat. This test can show whether you have a bacterial infection.
                
A chest x ray. A chest x ray takes a picture of your heart and lungs. This test can help diagnose conditions such as pneumonia and lung cancer.
                
Lung function tests. These tests measure how much air you can breathe in and out, how fast you can breathe air out, and how well your lungs deliver oxygen to your blood. Lung function tests can help diagnose asthma and other conditions.
                
An x ray of the sinuses. This test can help diagnose a sinus infection.
Question: What is (are) Congenital Heart Defects ?
Answer: Congenital (kon-JEN-ih-tal) heart defects are problems with the heart's structure that are present at birth. These defects can involve:
                
The interior walls of the heart
                
The valves inside the heart
                
The arteries and veins that carry blood to the heart or the body
                
Congenital heart defects change the normal flow of blood through the heart.
                
There are many types of congenital heart defects. They range from simple defects with no symptoms to complex defects with severe, life-threatening symptoms.
                
Congenital heart defects are the most common type of birth defect. They affect 8 out of every 1,000 newborns. Each year, more than 35,000 babies in the United States are born with congenital heart defects.
                
Many of these defects are simple conditions. They need no treatment or are easily fixed. Some babies are born with complex congenital heart defects. These defects require special medical care soon after birth.
                
The diagnosis and treatment of complex heart defects has greatly improved over the past few decades. As a result, almost all children who have complex heart defects survive to adulthood and can live active, productive lives.
                
Most people who have complex heart defects continue to need special heart care throughout their lives. They may need to pay special attention to how their condition affects issues such as health insurance, employment, birth control and pregnancy, and other health issues.
                
In the United States, more than 1 million adults are living with congenital heart defects.
Question: What causes Congenital Heart Defects ?
Answer: If your child has a congenital heart defect, you may think you did something wrong during your pregnancy to cause the problem. However, doctors often don't know why congenital heart defects occur.
                
Heredity may play a role in some heart defects. For example, a parent who has a congenital heart defect may be more likely than other people to have a child with the defect. Rarely, more than one child in a family is born with a heart defect.
                
Children who have genetic disorders, such as Down syndrome, often have congenital heart defects. In fact, half of all babies who have Down syndrome have congenital heart defects.
                
Smoking during pregnancy also has been linked to several congenital heart defects, including septal defects.
                
Researchers continue to search for the causes of congenital heart defects.
Question: What are the symptoms of Congenital Heart Defects ?
Answer: Many congenital heart defects cause few or no signs and symptoms. A doctor may not even detect signs of a heart defect during a physical exam.
                
Some heart defects do cause signs and symptoms. They depend on the number, type, and severity of the defects. Severe defects can cause signs and symptoms, usually in newborns. These signs and symptoms may include:
                
Rapid breathing
                
Cyanosis (a bluish tint to the skin, lips, and fingernails)
                
Fatigue (tiredness)
                
Poor blood circulation
                
Congenital heart defects don't cause chest pain or other painful symptoms.
                
Heart defects can cause heart murmurs (extra or unusual sounds heard during a heartbeat). Doctors can hear heart murmurs using a stethoscope. However, not all murmurs are signs of congenital heart defects. Many healthy children have heart murmurs.
                
Normal growth and development depend on a normal workload for the heart and normal flow of oxygen-rich blood to all parts of the body. Babies who have congenital heart defects may have cyanosis and tire easily while feeding. As a result, they may not gain weight or grow as they should.
                
Older children who have congenital heart defects may get tired easily or short of breath during physical activity.
                
Many types of congenital heart defects cause the heart to work harder than it should. With severe defects, this can lead to heart failure. Heart failure is a condition in which the heart can't pump enough blood to meet the body's needs. Symptoms of heart failure include:
                
Shortness of breath or trouble breathing
                
Fatigue with physical activity
                
A buildup of blood and fluid in the lungs
                
Swelling in the ankles, feet, legs, abdomen, and veins in the neck
Question: What is (are) Aplastic Anemia ?
Answer: Aplastic anemia (a-PLAS-tik uh-NEE-me-uh) is a blood disorder in which the body's bone marrow doesn't make enough new blood cells. Bone marrow is a sponge-like tissue inside the bones. It makes stem cells that develop into red blood cells, white blood cells, and platelets (PLATE-lets).
                
Red blood cells carry oxygen to all parts of your body. They also carry carbon dioxide (a waste product) to your lungs to be exhaled. White blood cells help your body fight infections. Platelets are blood cell fragments that stick together to seal small cuts or breaks on blood vessel walls and stop bleeding.
                
It's normal for blood cells to die. The lifespan of red blood cells is about 120 days. White blood cells live less than a day. Platelets live about 6 days. As a result, your bone marrow must constantly make new blood cells.
                
If your bone marrow can't make enough new blood cells, many health problems can occur. These problems include irregular heartbeats called arrhythmias (ah-RITH-me-ahs), an enlarged heart, heart failure, infections, and bleeding. Severe aplastic anemia can even cause death.
                
Overview
                
Aplastic anemia is a type of anemia. The term "anemia" usually refers to a condition in which your blood has a lower than normal number of red blood cells. Anemia also can occur if your red blood cells don't contain enough hemoglobin (HEE-muh-glow-bin). This iron-rich protein helps carry oxygen to your body.
                
In people who have aplastic anemia, the body doesn't make enough red blood cells, white blood cells, and platelets. This is because the bone marrow's stem cells are damaged. (Aplastic anemia also is called bone marrow failure.)
                
Many diseases, conditions, and factors can damage the stem cells. These conditions can be acquired or inherited. "Acquired" means you aren't born with the condition, but you develop it. "Inherited" means your parents passed the gene for the condition on to you.
                
In many people who have aplastic anemia, the cause is unknown.
                
Outlook
                
Aplastic anemia is a rare but serious disorder. It can develop suddenly or slowly. The disorder tends to get worse over time, unless its cause is found and treated. Treatments for aplastic anemia include blood transfusions, blood and marrow stem cell transplants, and medicines.
                
With prompt and proper care, many people who have aplastic anemia can be successfully treated. Blood and marrow stem cell transplants may offer a cure for some people who have aplastic anemia.
Question: What causes Aplastic Anemia ?
Answer: Damage to the bone marrow's stem cells causes aplastic anemia. When stem cells are damaged, they don't grow into healthy blood cells.
                
The cause of the damage can be acquired or inherited. "Acquired" means you aren't born with the condition, but you develop it. "Inherited" means your parents passed the gene for the condition on to you.
                
Acquired aplastic anemia is more common, and sometimes it's only temporary. Inherited aplastic anemia is rare.
                
In many people who have aplastic anemia, the cause is unknown. Some research suggests that stem cell damage may occur because the body's immune system attacks its own cells by mistake.
                
Acquired Causes
                
Many diseases, conditions, and factors can cause aplastic anemia, including:
                
Toxins, such as pesticides, arsenic, and benzene.
                
Radiation and chemotherapy (treatments for cancer).
                
Medicines, such as chloramphenicol (an antibiotic rarely used in the United States).
                
Infectious diseases, such as hepatitis, Epstein-Barr virus, cytomegalovirus (si-to-MEG-ah-lo-VI-rus), parvovirus B19, and HIV.
                
Autoimmune disorders, such as lupus and rheumatoid arthritis.
                
Pregnancy. (Aplastic anemia that occurs during pregnancy often goes away after delivery.)
                
Sometimes, cancer from another part of the body can spread to the bone and cause aplastic anemia.
                
Inherited Causes
                
Certain inherited conditions can damage the stem cells and lead to aplastic anemia. Examples include Fanconi anemia, Shwachman-Diamond syndrome, dyskeratosis (DIS-ker-ah-TO-sis) congenita, and Diamond-Blackfan anemia.
Question: Who is at risk for Aplastic Anemia? ?
Answer: Aplastic anemia is a rare but serious blood disorder. People of all ages can develop aplastic anemia. However, it's most common in adolescents, young adults, and the elderly. Men and women are equally likely to have it.
                
The disorder is two to three times more common in Asian countries.
                
Your risk of aplastic anemia is higher if you:
                
Have been exposed to toxins
                
Have taken certain medicines or had radiation or chemotherapy (treatments for cancer)
                
Have certain infectious diseases, autoimmune disorders, or inherited conditions
                
For more information, go to "What Causes Aplastic Anemia?"
Question: What are the symptoms of Aplastic Anemia ?
Answer: Lower than normal numbers of red blood cells, white blood cells, and platelets cause most of the signs and symptoms of aplastic anemia.
                
Signs and Symptoms of Low Blood Cell Counts
                

                
Red Blood Cells
                
The most common symptom of a low red blood cell count is fatigue (tiredness). A lack of hemoglobin in the blood causes fatigue. Hemoglobin is an iron-rich protein in red blood cells. It helps carry oxygen to the body.
                
A low red blood cell count also can cause shortness of breath; dizziness, especially when standing up; headaches; coldness in your hands or feet; pale skin; and chest pain.
                
If you don't have enough hemoglobin-carrying red blood cells, your heart has to work harder to move the reduced amount of oxygen in your blood. This can lead to arrhythmias (irregular heartbeats), a heart murmur, an enlarged heart, or even heart failure.
                
White Blood Cells
                
White blood cells help fight infections. Signs and symptoms of a low white blood cell count include fevers, frequent infections that can be severe, and flu-like illnesses that linger.
                
Platelets
                
Platelets stick together to seal small cuts or breaks on blood vessel walls and stop bleeding. People who have low platelet counts tend to bruise and bleed easily, and the bleeding may be hard to stop.
                
Common types of bleeding associated with a low platelet count include nosebleeds, bleeding gums, pinpoint red spots on the skin, and blood in the stool. Women also may have heavy menstrual bleeding.
                
Other Signs and Symptoms
                
Aplastic anemia can cause signs and symptoms that aren't directly related to low blood cell counts. Examples include nausea (feeling sick to your stomach) and skin rashes.
                
Paroxysmal Nocturnal Hemoglobinuria
                
Some people who have aplastic anemia have a condition called paroxysmal (par-ok-SIZ-mal) nocturnal hemoglobinuria (HE-mo-glo-bi-NOO-re-ah), or PNH. This is a red blood cell disorder. Most people who have PNH don't have any signs or symptoms.
                
If symptoms do occur, they may include:
                
Shortness of breath
                
Swelling or pain in the abdomen or swelling in the legs caused by blood clots
                
Blood in the urine
                
Headaches
                
Jaundice (a yellowish color of the skin or whites of the eyes)
                
In people who have aplastic anemia and PNH, either condition can develop first.
Question: What causes Disseminated Intravascular Coagulation ?
Answer: Some diseases and conditions can disrupt the body's normal blood clotting process and lead to disseminated intravascular coagulation (DIC). These diseases and conditions include:
                
Sepsis (an infection in the bloodstream)
                
Surgery and trauma
                
Cancer
                
Serious complications of pregnancy and childbirth
                
Examples of less common causes of DIC are bites from poisonous snakes (such as rattlesnakes and other vipers), frostbite, and burns.
                
The two types of DIC are acute and chronic. Acute DIC begins with clotting in the small blood vessels and quickly leads to serious bleeding. Chronic DIC causes blood clotting, but it usually doesn't lead to bleeding. Cancer is the most common cause of chronic DIC.
                
Similar Clotting Conditions
                
Two other conditions cause blood clotting in the small blood vessels. However, their causes and treatments differ from those of DIC.
                
These conditions are thrombotic thrombocytopenic purpura (throm-BOT-ik throm-bo-cy-toe-PEE-nick PURR-purr-ah), or TTP, and hemolytic-uremic syndrome (HUS). HUS is more common in children than adults. It's also more likely to cause kidney damage than TTP.
Question: Who is at risk for Disseminated Intravascular Coagulation? ?
Answer: Disseminated intravascular coagulation (DIC) is the result of an underlying disease or condition. People who have one or more of the following conditions are most likely to develop DIC:
                
Sepsis (an infection in the bloodstream)
                
Surgery and trauma
                
Cancer
                
Serious complications of pregnancy and childbirth
                
People who are bitten by poisonous snakes (such as rattlesnakes and other vipers), or those who have frostbite or burns, also are at risk for DIC.
Question: How to diagnose Disseminated Intravascular Coagulation ?
Answer: Your doctor will diagnose disseminated intravascular coagulation (DIC) based on your medical history, a physical exam, and test results. Your doctor also will look for the cause of DIC.
                
Acute DIC requires emergency treatment. The condition can be life threatening if it's not treated right away. If you have signs or symptoms of severe bleeding or blood clots, call 911 right away.
                
Medical History and Physical Exam
                
Your doctor will ask whether you have or have had any diseases or conditions that can trigger DIC. For more information about these diseases and conditions, go to "What Causes Disseminated Intravascular Coagulation?"
                
Your doctor will ask about signs and symptoms of blood clots and bleeding. He or she also will do a physical exam to look for signs and symptoms of blood clots and internal and external bleeding. For example, your doctor may look for bleeding from your gums.
                
Diagnostic Tests
                
To diagnose DIC, your doctor may recommend blood tests to look at your blood cells and the clotting process. For these tests, a small amount of blood is drawn from a blood vessel, usually in your arm.
                
Complete Blood Count and Blood Smear
                
A complete blood count (CBC) measures the number of red blood cells, white blood cells, and platelets in your blood.
                
Platelets are blood cell fragments that help with blood clotting. Abnormal platelet numbers may be a sign of a bleeding disorder (not enough clotting) or a thrombotic disorder (too much clotting).
                
A blood smear is a test that may reveal whether your red blood cells are damaged.
                
Tests for Clotting Factors and Clotting Time
                
The following tests examine the proteins active in the blood clotting process and how long it takes them to form a blood clot.
                
PT and PTT tests. These tests measure how long it takes blood clots to form.
                
Serum fibrinogen. Fibrinogen is a protein that helps the blood clot. This test measures how much fibrinogen is in your blood.
                
Fibrin degradation. After blood clots dissolve, substances called fibrin degradation products are left behind in the blood. This test measures the amount of these substances in the blood.