NothingMuch/GO-Terms huggingface dataset:
The attachment of a melanocyte to another cell via adhesion molecules.
melanocyte adhesion
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antineoplastic agent stimulus. An antineoplastic agent is a substance that inhibits or prevents the proliferation of neoplasms.
response to antineoplastic agent
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carboplatin stimulus.
response to carboplatin
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antimetabolite stimulus. An antimetabolite is a substance which is structurally similar to a metabolite but which competes with it or replaces it, and so prevents or reduces its normal utilization.
response to antimetabolite
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 5-fluoro-2'-deoxyuridine stimulus. 5-fluoro-2'-deoxyuridine is a pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; it is used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
response to 5-fluoro-2'-deoxyuridine
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytarabine stimulus.
response to cytarabine
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antipsychotic drug stimulus. Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect.
response to antipsychotic drug
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an olanzapine stimulus.
response to olanzapine
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a perphenazine stimulus. Perphenazine is a phenothiazine derivative having a chloro substituent at the 2-position and a 3-propyl group at the N-10 position.
response to perphenazine
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a quetiapine stimulus.
response to quetiapine
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a risperidone stimulus.
response to risperidone
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ziprasidone stimulus. Ziprasidone is a piperazine compound having 1,2-benzothiazol-3-yl- and 2-(6-chloro-1,3-dihydro-2-oxindol-5-yl)ethyl substituents attached to the nitrogen atoms.
response to ziprasidone
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a clozapine stimulus.
response to clozapine
The lipid bilayer surrounding a host cell endocytic vesicle.
host cell endocytic vesicle membrane
The selective elimination of senescent neutrophils from the body by autoregulatory mechanisms.
neutrophil clearance
Catalysis of the reaction: D-leucyl-tRNA(Leu) = D-leucine + tRNA(Leu). Removal of a D-leucine from a charged tRNA(Leu).
D-leucyl-tRNA(Leu) deacylase activity
The covalent attachment of a UDP-glucose residue to a substrate molecule.
UDP-glucosylation
A hexameric protein complex composed of MCM8 and MCM9 and involved in homologous recombination repair following DNA interstrand cross-links.
MCM8-MCM9 complex
The glycosylation of a protein by addition of N-acetylglucosamine via the O3 atom of peptidyl-threonine, forming O3-N-acetylglucosamine-L-threonine.
protein O-GlcNAcylation via threonine
Binding to a member of the MDM2/MDM4 protein family, comprising negative regulators of p53.
MDM2/MDM4 family protein binding
The process in which the migration of an axon growth cone of a spinal sensory neuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A spinal sensory neuron is a sensory neuron that project to the spinal cord.
spinal sensory neuron axon guidance
Simple or compound process of epithelial glial cells with a spherical head that inserts into photoreceptor axons. Capitate projections have only been observed in Brachycera (flies).
capitate projection
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a raffinose stimulus.
cellular response to raffinose
Small granular inclusions (about 1-3 microns in diameter) found in the anterior horn cells, and appearing either singly or in a group. Sometimes they are arranged in small beaded chains. Bunina bodies express cystatin C and consist of electron-dense amorphous material that contains tubules or vesicular structures. The amorphous material frequently includes a cytoplasmic island containing neurofilaments and other micro-organelles.
Bunina body
Cellular inclusion consisting of circular areas filled with fine slender filaments about 10 nanometers in diameter, delimited by a wall of varying complexity (either a single continuous membrane or a tubular network consisting of a fine filamentous material giving the wall a honeycomb appearance). Fibrillary inclusions are found in the cytoplasm of giant cells of Dieters in the lateral vestibular nucleus of the rat; similar structures have been described in the ventral cochlear nucleus, spinal cord, and substantia nigra.
fibrillary inclusion
The process in which a relatively unspecialized cell acquires specialized features of a hippocampal interneuron.
hippocampal interneuron differentiation
Cytoplasmic inclusion similar to a classical Lewy body but lacking a halo of protein fibrils.
cortical Lewy body
Cytoplasmic, ball-like inclusion resembling a nucleolus and consisting of a convoluted network of electron-opaque strands embedded in a less dense matrix. It measures approximately 0.9 microns and lacks a limiting membrane. Its strands (diameter = 400-600 A) appear to be made of an entanglement of tightly packed filaments and particles approximately 25-50 A thick. Cytochemical studies suggest the presence of nonhistone proteins and some RNA. Usually only one such structure is present in a cell, and it appears to occur in most ganglion cells. Although they can be seen anywhere in the cell body, nematosomes are typically located in the perinuclear cytoplasm, where they are often associated with smooth-surfaced and coated vesicles.
nematosome
Cellular inclusion composed of numerous tau fibrils arranged in a disorderly array. Tau protein is a major component, though Pick bodies also contain ubiquitin, alpha-synuclein, and apolipoprotein E.
Pick body
Intracytoplasmic filamentous structure frequently encountered in preparations immunostained for ubiquitin.
skein-like inclusion
The regrowth of lost or destroyed liver.
liver regeneration
Dense particles of heterochromatin, consisting of a loosely twisted strand about 600 Angstrom thick, found associated with the nucleolus.
nucleolus-associated heterochromatin
An intermediate filament composed of glial fibrillary acidic protein (GFAP) and found in astrocytes.
glial filament
Catalysis of the ligation of an amino acid to another amino acid via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate, carried out by a nonribosomal peptide synthase.
amino acid ligation activity by nonribosomal peptide synthase
Either of the ends of a mitotic spindle, a spindle that forms as part of mitosis, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules.
mitotic spindle pole
The process in which a relatively unspecialized cell acquires specialized features of a hippocampal pyramidal neuron, a pyramidal cell of the hippocampus.
hippocampal pyramidal neuron differentiation
An electron dense body which may contain granules.
dense body
A dendrite of a hippocampal CA3 pyramidal cell.
CA3 pyramidal cell dendrite
A configuration of neuron spines found on ciliary ganglion neurons in the embryonic and adult brain consisting of patches of closely spaced spines lying flat against the soma.
spine mat
Small finger-like extension of a Schwann cell that contacts the nodal membrane.
Schwann cell microvillus
Paranodal terminations of Schwann cells that do not directly contact the paranodal axon membrane. Usually found in thicker myelin.
spiny bracelet of Nageotte
Elongated neuronal process, often with side branches and more than one branching point, described in brains of patients with Parkinson's disease. Lewy neurites stain positively for ubiquitin in brainstem and forebrain regions affected in Parkinson's disease.
Lewy neurite
Spine-like process found on some neurons, e.g., periglomerular cells of olfactory cortex.
gemmule
Large complex spine protruding from a dendrite. Each excrescence is formed by a cluster of spine heads.
thorny excrescence
Spine emanating from the cell soma of a neuron.
somatic spine
The volume enclosed by the outermost membrane of a multivesicular body.
multivesicular body lumen
The lipid bilayer surrounding a multivesicular body internal vesicle.
multivesicular body, internal vesicle membrane
The volume enclosed by the membrane of the multivesicular body internal vesicle.
multivesicular body, internal vesicle lumen
A trimeric protein complex made up of an H-NS homodimer and an Hha monomer. In Enterobacteriaceae, this complex negatively regulates transcription of a range of genes.
H-NS-Hha complex
A ubiquitin ligase complex found to be involved in post-replicative bypass of UV-damaged DNA and UV mutagenesis. In S. cerevisiae, the complex contains the ubiquitin conjugating enzyme Rad6 and Rad18, a protein containing a RING finger motif and a nucleotide binding motif. The yeast Rad6-Rad18 heterodimer has ubiquitin conjugating activity, binds single-stranded DNA, and possesses single-stranded DNA-dependent ATPase activity.
Rad6-Rad18 complex
A base-excision repair, AP site formation process occurring via excision of a deaminated base.
base-excision repair, AP site formation via deaminated base removal
A branched cellular projection (or cytoplasmic extension) that is extended from the surface of a dendritic immune cell, and which enables the cell to sample luminal pathogens and increase the surface area for antigen presentation to T cells.
dendritic cell dendrite
A cardiac myofibril is a myofibril specific to cardiac muscle cells.
cardiac myofibril
A bipolar filament composed of myosin II molecules.
myosin II filament
A specialized envelope lying outside the cell membrane of a spore derived from a product of meiosis.
sexual spore wall
A specialized envelope lying outside the cell membrane of a spore derived from an asexual process. Examples of this process are found in bacterial and fungal species.
asexual spore wall
A parallel bundle of actin filaments at the core of a microvillus.
microvillar actin bundle
A protein-DNA complex consisting of a higher-order oligomer of strand exchange proteins (recombinases) on single-stranded DNA.
DNA recombinase complex
A protein-DNA complex formed through interaction of the protein(s) with an interferon-stimulated response element (ISRE) in the DNA.
protein-DNA ISRE complex
The controlled shedding of a seed.
seed abscission
Set of two basal bodies found in Giardia species (trophozoite stage). It comprises the anterior and ventral basal bodies located to the right of the left nucleus of the trophozoite when viewed dorsally.
left lateral basal body pair
Set of two basal bodies found in Giardia species (trophozoite stage). It comprises the caudal and posteriolateral basal bodies located to the right of the left nucleus of the trophozoite when viewed dorsally.
left middle basal body pair
Set of two basal bodies found in Giardia species (trophozoite stage). It comprises the anterior and ventral basal bodies located to the left of the right nucleus of the trophozoite when viewed dorsally.
right lateral basal body pair
Set of two basal bodies found in Giardia species (trophozoite stage). It comprises the caudal and posteriolateral basal bodies located to the left of the right nucleus of the trophozoite when viewed dorsally.
right middle basal body pair
Set of four basal bodies found in Giardia species (trophozoite stage). It comprises the left lateral basal body pair and the left middle basal body pair (i.e. the anterior, ventral, caudal and posteriolateral basal bodies located to the right of the left nucleus of the trophozoite when viewed dorsally).
left tetrad
Set of four basal bodies found in Giardia species (trophozoite stage). It comprises the right lateral basal body pair and the right middle basal body pair (i.e. the anterior, ventral, caudal and posteriolateral basal bodies located to the left of the right nucleus of the trophozoite when viewed dorsally).
right tetrad
Region of the ventral side of the cell body found in Giardia species (trophozoite stage). It is located posterior on either side of the ventral groove; the upper boundary is the ventral disc, and the lower boundary is marked by the posteriolateral flagella.
lateral shield
The specialized envelope lying outside the cell membrane of a cyst. A cyst is a resting or dormant stage of a microorganism, usually a bacterium or a protist or rarely an invertebrate animal, that helps the organism to survive in unfavorable environmental conditions. In protists such as protozoan parasites alternating cystic- and non-cystic stages, the cyst wall is usually composed of carbohydrates and proteins.
cyst wall
One of the two nuclei found in Giardia species (trophozoite stage). It is located on the left side of the cell when viewed from the dorsal side.
left nucleus
One of the two nuclei found in Giardia species (trophozoite stage). It is located on the right side of the cell when viewed from the dorsal side.
right nucleus
A heterodimer involved in the recognition of base-base and small insertion/deletion mismatches. In S. cerevisiae the complex consists of two subunits, Mlh1 and Mlh3.
MutLgamma complex
A xylanase activity that acts on one of the ends of a xylan polymer which does not contain side chains.
exoxylanase activity
Combining with amylin to initiate a change in cell activity.
amylin receptor activity
Binding to amylin.
amylin binding
A SNARE complex that is capable of fusing intracellular vesicles to the plasma membrane of platelets for exocytosis of alpha-granules or dense granules. Contains isoforms of VAMP, SNAP and syntaxin proteins. Ternary SNARE complexes interact in a circular array to form ring complexes or channels around the membrane fusion. A common composition in human is VAMP-8, SNAP-23 and syntaxin-2 or -4.
platelet SNARE complex
Binding to a member of the serpin protein family (serine protease inhibitors or classified inhibitor family I4). Serpins are a broadly distributed family of protease inhibitors that use a conformational change to inhibit target enzymes. They are central in controlling many important proteolytic cascades. The majority of serpins inhibit serine proteases, but serpins that inhibit caspases and papain-like cysteine proteases have also been identified. Rarely, serpins perform a non-inhibitory function; for example, several human serpins function as hormone transporters and certain serpins function as molecular chaperones or tumor suppressors.
serpin family protein binding
Catalysis of the reaction: 3',5'-nucleoside bisphosphate + H20 = 5'-nucleoside monophosphate + phosphate.
3',5'-nucleotide bisphosphate phosphatase activity
A nuclear ubiquitin ligase multiprotein complex located in the inner nuclear membrane (INM) that recognizes and ubiquitinates misfolded INM proteins and also some proteins involved in sterol biosynthesis, during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligases Asi1p and Asi3p.
Asi complex
An SCF ubiquitin ligase complex in which the F-box protein is Cdc4 in S. cerevisiae.
SCF-Cdc4 ubiquitin ligase complex
An SCF ubiquitin ligase complex in which the F-box protein is Ctf13 in S. cerevisiae.
SCF-Ctf13 ubiquitin ligase complex
An SCF ubiquitin ligase complex in which the F-box protein is Das1 in S. cerevisiae.
SCF-Das1 ubiquitin ligase complex
An SCF ubiquitin ligase complex in which the F-box protein is Dia2 in S. cerevisiae (Pof3 in S. pombe).
SCF-Dia2/Pof3 ubiquitin ligase complex
An SCF ubiquitin ligase complex in which the F-box protein is Grr1 in S. cerevisiae (Pof2 in S. pombe).
SCF-Grr1/Pof2 ubiquitin ligase complex
An SCF ubiquitin ligase complex in which the F-box protein is Mdm30 in S. cerevisiae.
SCF-Mdm30 ubiquitin ligase complex
An SCF ubiquitin ligase complex in which the F-box protein is Met30 in S. cerevisiae (Pof1 in S pombe).
SCF-Met30/Pof1 ubiquitin ligase complex
An SCF ubiquitin ligase complex in which the F-box protein is Rcy1 in S. cerevisiae (Pof6 in S. pombe).
SCF-Rcy1/Pof6 ubiquitin ligase complex
An SCF ubiquitin ligase complex in which the F-box protein is Saf1 in S. cerevisiae (Pof9 in S. pombe).
SCF-Saf1/Pof9 ubiquitin ligase complex
An SCF ubiquitin ligase complex in which the F-box protein is Skp2 in S. cerevisiae.
SCF-Skp2 ubiquitin ligase complex
An SCF ubiquitin ligase complex in which the F-box protein is Ufo1 in S. cerevisiae (Pof10 in S. pombe).
SCF-Ufo1/Pof10 ubiquitin ligase complex
An SCF ubiquitin ligase complex in which the F-box protein is YDR131C in S. cerevisiae.
SCF-YDR131C ubiquitin ligase complex
An SCF ubiquitin ligase complex in which the F-box protein is YLR352W in S. cerevisiae.
SCF-YLR352W ubiquitin ligase complex
An SCF ubiquitin ligase complex in which the F-box protein is Hrt3 in S. cerevisiae (Pof7 in S. pombe).
SCF-Hrt3/Pof7 ubiquitin ligase complex
A horn-shaped dinoflagellate apex found in thecate species.
dinoflagellate apical horn
A horn-shaped dinoflagellate antapex found in thecate species.
dinoflagellate antapical horn
Small membrane vesicle (< 1 um) that buds off a prokaryotic cell plasma membrane, able to carry proteins, phospholipids, lipopolysaccharides, nucleic acids, viruses, and more. Important in intercellular communication and pathogenesis; can exist within host cells.
bacterial extracellular vesicle
Eye-like subcellular structure found in dinoflagellates (a large group of single-celled eukaryotes). Consists of subcellular analogues to a cornea, lens, iris, and retina. Ocelloids are built from pre-existing organelles, including a cornea-like layer made of mitochondria and a retinal body made of anastomosing plastids.
ocelloid
A telomere maintenance process that occurs by base-excision repair of telomeric DNA in response to DNA damage. Telomeric sequences are particularly susceptible to oxidative DNA damage, due to their G-rich nature.
telomere maintenance via base-excision repair
The process in which vesicles formed at the trans-Golgi network are directed to the plasma membrane surrounding the base of the cilium, including the ciliary pocket, mediated by molecules at the vesicle membrane and target membrane surfaces.
vesicle targeting, trans-Golgi to periciliary membrane compartment
Binds to and modulates the activity of dolichol-phosphate-mannose synthase.
dolichol-phosphate-mannose synthase regulator activity
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a viscosity stimulus.
cellular response to viscosity
An intracellular non-membrane-bounded organelle found in multi-ciliated sperm cells of some primitive land plants, and consisting of many radially arranged ninefold symmetric cylinders. The blepharoplast is involved in de novo formation of multiple centrioles; it enlarges and then disintegrates into many procentrioles, which elongate and ultimately nucleate cilia on the surface of the sperm cell.
blepharoplast
A section of the Actinobacterium-type cell wall composed of (phenyl)phthiocerol, phthiodiolone, phthiotriol dimycocerosate, diphthioceranate and other compounds.
DIM/DIP cell wall layer
The process by which, in some fungal species, hyphae grow as a network of invasive thread-like filaments formed from chains of attached cells within a solid or semi-solid substrate.
substrate mycelium formation
Any process that stops, prevents or reduces the rate of ferrichrome biosynthetic process in response to an iron stimulus.
negative regulation of ferrichrome biosynthetic process in response to iron
A hair-like structure covering the flagella found in some algae (heterokonts and cryptophytes). It is approximately 15 nm in diameter, and usually consist of a tubular shaft that itself terminates in smaller hairs. It is composed of glycoproteins and, likely, carbohydrates. Mastigonemes may assist in locomotion by increasing the surface area of a flagellum.
mastigoneme
The process in which the 5' end of a pre-tRNA molecule is converted to that of a mature tRNA in the mitochondrion.
mitochondrial tRNA 5'-end processing
Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis of RNA from ribonucleotide triphosphates in the presence of a nucleic acid template, via extension of the 5'-end.
3'-5' RNA polymerase activity
Any process that modulates the stability of DNA.
regulation of DNA stability
A membrane bending process mediated by clathrin.
clathrin-mediated membrane bending
The aggregation, arrangement and bonding together of a set of components to form a virus tail fiber.
virus tail fiber assembly
A short structure attached to an icosahedral virion capsid, and used for attachment to the host cell.
icosahedral viral capsid, spike
A fiber attached to the collar structure of some icosahedral viral capsids.
icosahedral viral capsid, collar fiber
A fiber attached to the neck at the base of some icosahedral viral capsids.
icosahedral viral capsid, neck fiber
The encapsulation of the viral DNA genome within the capsid, which proceeds via cleavage of the viral DNA at specific sites to produce 3' protruding ends.
viral DNA genome packaging, 3' extended cos packaging
The encapsulation of the viral DNA genome within the capsid, which proceeds via cleavage of the viral DNA at specific sites to produce 5' protruding ends.
viral DNA genome packaging, 5' extended cos packaging
The aggregation, arrangement and bonding together of a set of components to form a virus baseplate.
virus baseplate assembly
Binding to G-rich, single-stranded, telomere-associated DNA.
G-rich strand telomeric DNA binding
The process of removing one or more phosphate groups from the 3' end of a polynucleotide.
polynucleotide 3' dephosphorylation
The process of removing one or more phosphate groups from the 5' end of a polynucleotide.
polynucleotide 5' dephosphorylation
The generation of hematopoietic stem cells from hemogenic endothelial cells by a process that includes tight-junction dissolution and loss of cell polarity followed by delamination from the endothelium.
endothelial to hematopoietic transition
The series of events in which a high humidity stimulus is detected and converted into a molecular signal as a part of the sensory detection of high humidity.
detection of high humidity stimulus involved in sensory perception