NothingMuch/GO-Terms huggingface dataset:
Catalysis of the reaction: all-trans-retinoate + O2 + reduced  = all-trans-(4S)-hydroxyretinoate + H+ + H2O + oxidized .
all-trans retinoic acid 4-hydrolase activity
Catalysis of the reaction: all-trans-retinoate + O2 + reduced  = all-trans-18-hydroxyretinoate + H+ + H2O + oxidized .
all-trans retinoic acid 18-hydroxylase activity
Catalysis of the reaction: O2 + reduced  + testosterone = 16beta,17beta-dihydroxyandrost-4-en-3-one + H+ + H2O + oxidized .
testosterone 16-beta-hydroxylase activity
Catalysis of the reaction:2 H+ + O2 + 2 reduced  + secalciferol = calcitetrol + H2O + 2 oxidized .
secalciferol 1-monooxygenase activity
Catalysis of the reaction: N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + O2 + reduced  = H+ + H2O + N-(8,9-epoxy-5Z,11Z,14Z-eicosatrienoyl)-ethanolamine + oxidized .
anandamide 8,9 epoxidase activity
Catalysis of the reaction: N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + O2 + reduced  = H+ + H2O + N-(11,12-epoxy-5Z,8Z,14Z-eicosatrienoyl)-ethanolamine + oxidized .
anandamide 11,12 epoxidase activity
Catalysis of the reaction: N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + O2 + reduced  = H+ + H2O + N-(14,15-epoxy-5Z,8Z,11Z-eicosatrienoyl)-ethanolamine + oxidized .
anandamide 14,15 epoxidase activity
Catalysis of the reaction: alpha-L-rhamnose = beta-L-rhamnose.
L-rhamnose mutarotase activity
Catalysis of the reactions: beta-D-ribopyranose = beta-D-ribofuranose, and beta-allofuranose = beta-allopyranose.
D-ribose pyranase activity
A microtubule minus end that is part of a cytoplasmic microtubule.
cytoplasmic microtubule minus-end
The organization process that preserves a microtubule bundle in a stable functional or structural state.
microtubule bundle maintenance
Any process that modulates the size of a lysosome.
regulation of lysosome size
A cellular anatomical entity that is part of the actin cytoskeleton and results in a wave-like propagation of actin networks. It consists of dynamic structures traveling on the ventral (substrate-attached) side of the cell during cell migration, cytokinesis, adhesion and neurogenesis.
actin wave
Catalysis of the reaction: peregrinol diphosphate = diphosphate + labd-13(16),14-diene-9-ol.
Labd-13(16),14-diene-9-ol synthase activity
Catalysis of the reaction: H2O + peregrinol diphosphate = diphosphate + viteagnusin D.
Viteagnusin D synthase activity
Catalysis of the reaction:9alpha-copalyl diphosphate + H2O = (13S)-vitexifolin A + diphosphate.
(13S)-vitexifolin A synthase activity
Catalysis of the reaction: 8-hydroxycopalyl diphosphate = (13R)-manoyl oxide + diphosphate.
manoyl oxide synthase activity
The the regeneration process by which a damaged or lost root regrows or re-differentiates. This process may occur via de-differentiation and subsequent reprogramming of somatic cells or activation of existing undifferentiated (meristematic) cells to form a new root meristem and subsequently new root.
root regeneration
Catalysis of the reaction: peroxynitrite = nitrate.
peroxynitrite isomerase activity
Any process that increases the rate, frequency or extent of adult somatic muscle development.
positive regulation of adult somatic muscle development
Any process that decreases the rate, frequency or extent of adult somatic muscle development.
negative regulation of adult somatic muscle development
Any process that decreases the rate, frequency or extent of larval somatic muscle development.
negative regulation of larval somatic muscle development
Any process that increases the rate, frequency or extent of larval somatic muscle development.
positive regulation of larval somatic muscle development
The chemical reactions and pathways resulting in the breakdown of F2-isoprostane.
F2-isoprostane catabolic process
The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an ionocyte. Ionocytes are specialized epithelial cells that contribute to osmotic homeostasis.
ionocyte differentiation
The volume enclosed by an exocytic vesicle.
exocytic vesicle lumen
A intracellular vesicle that is part of a chloroplast.
chloroplast vesicle
The process of producing a cleistothecium, a closed sexual fruiting body that contains ascospores in linear asci. Cleistothecia are present in some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella.
cleistothecium formation
Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
cysteine-type aminopeptidase activity
Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
metalloaminopeptidase activity
Catalysis of the hydrolysis of internal peptide bonds in a polypeptide chain by a mechanism involving a glutamate/glutamine catalytic dyad.
glutamic-type endopeptidase activity
Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
serine-type aminopeptidase activity
Catalysis of the hydrolysis of a peptide bond in an oligopeptide, i.e. a molecule containing a small number (2 to 20) of amino acid residues connected by peptide bonds.
oligopeptidase activity
Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N3-methylpseudouridine.
rRNA (pseudouridine-N3-)-methyltransferase activity
Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing 2'-O-methylguanosine.
rRNA (guanosine-2'-O-)-methyltransferase activity
Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing C5-methyluridine.
rRNA (uridine-C5-)-methyltransferase activity
Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N3-methyluridine.
rRNA (uridine-N3-)-methyltransferase activity
Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N7-methylguanine.
rRNA (guanine-N7-)-methyltransferase activity
Binding to fibrinogen, a highly soluble hexameric glycoprotein complex that is found in blood plasma and is converted to fibrin by thrombin in the coagulation cascade.
fibrinogen binding
Binding to a type V collagen trimer.
collagen V binding
Combining with thrombospondin and transmitting the signal to initiate a change in cell activity.
thrombospondin receptor activity
The process in which tRNA genes, which are not linearly connected on the chromosome, are transported in three dimensions to, and maintained together in, the nucleolus. This clustered positioning leads to transcriptional silencing of nearby RNA polymerase II promoters (termed tRNA gene mediated (tgm) silencing) in S. cerevisiae.
tRNA gene clustering
Binding to the D- or L-enantiomer of fructose, the ketohexose arabino-hex-2-ulose.
fructose binding
Binding to a proline-rich region, i.e. a region that contains a high proportion of proline residues, in a protein.
proline-rich region binding
A SNARE complex that contains syntaxin 6, syntaxin 16, and Vti1a (or orthologs thereof).
syntaxin-6-syntaxin-16-Vti1a complex
A secretory organelle that forms part of the apical complex; a small, threadlike structure located is close proximity to the subpellicular microtubules. Its contents include a rhomboid protease (PfROM1 in Plasmodium falciparum) that moves from the lateral asymmetric localization to the merozoite apical pole and the posterior pole upon release of merozoites from schizonts.
mononeme
The regulated release of the aqueous layer of the tear film from the lacrimal glands. Tears are the liquid product of a process of lacrimation to clean and lubricate the eyes. Tear fluid contains water, mucin, lipids, lysozyme, lactoferrin, lipocalin, lacritin, immunoglobulins, glucose, urea, sodium, and potassium.
tear secretion
Enables the transmembrane transfer of a potassium cation by a channel that opens when a chloride ion has been bound by the channel complex or one of its constituent parts.
chloride-activated potassium channel activity
The intracellular plane, located halfway between the poles of the spindle, where chromosomes align during metaphase of mitotic or meiotic nuclear division.
metaphase plate
Binding to the delta subunit of the catenin complex.
delta-catenin binding
A protein complex that acts as a receptor for the cytokine ciliary neurotrophic factor (CNTF). In humans the receptor complex is a hexamer composed of two molecules each of CNTF and CNTFR and one molecule each of gp130 and LIFR.
ciliary neurotrophic factor receptor complex
Catalysis of the hydrolysis of peptide bonds between an alpha-carboxyl group and an alpha-amino group within the small conjugating protein SUMO.
SUMO-specific endopeptidase activity
The process of coupling alanine to alanyl-tRNA in a mitochondrion, catalyzed by alanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
mitochondrial alanyl-tRNA aminoacylation
The process of coupling arginine to arginyl-tRNA in a mitochondrion, catalyzed by arginyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
mitochondrial arginyl-tRNA aminoacylation
The process of coupling asparagine to asparaginyl-tRNA in a mitochondrion, catalyzed by asparaginyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
mitochondrial asparaginyl-tRNA aminoacylation
The process of coupling aspartate to aspartyl-tRNA in a mitochondrion, catalyzed by aspartyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
mitochondrial aspartyl-tRNA aminoacylation
The process of coupling cysteine to cysteinyl-tRNA in a mitochondrion, catalyzed by cysteinyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
mitochondrial cysteinyl-tRNA aminoacylation
The process of coupling glutamine to glutaminyl-tRNA in a mitochondrion, catalyzed by glutaminyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
mitochondrial glutaminyl-tRNA aminoacylation
The process of coupling glutamate to glutamyl-tRNA in a mitochondrion, catalyzed by glutamyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
mitochondrial glutamyl-tRNA aminoacylation
The process of coupling glycine to glycyl-tRNA in a mitochondrion, catalyzed by glycyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
mitochondrial glycyl-tRNA aminoacylation
The process of coupling histidine to histidyl-tRNA in a mitochondrion, catalyzed by histidyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
mitochondrial histidyl-tRNA aminoacylation
The process of coupling isoleucine to isoleucyl-tRNA in a mitochondrion, catalyzed by isoleucyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
mitochondrial isoleucyl-tRNA aminoacylation
The process of coupling leucine to leucyl-tRNA in a mitochondrion, catalyzed by leucyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
mitochondrial leucyl-tRNA aminoacylation
The process of coupling lysine to lysyl-tRNA in a mitochondrion, catalyzed by lysyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
mitochondrial lysyl-tRNA aminoacylation
The process of coupling methionine to methionyl-tRNA in a mitochondrion, catalyzed by methionyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
mitochondrial methionyl-tRNA aminoacylation
The process of coupling phenylalanine to phenylalanyl-tRNA in a mitochondrion, catalyzed by phenylalanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
mitochondrial phenylalanyl-tRNA aminoacylation
The process of coupling proline to prolyl-tRNA in a mitochondrion, catalyzed by prolyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
mitochondrial prolyl-tRNA aminoacylation
The process of coupling serine to seryl-tRNA in a mitochondrion, catalyzed by seryl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
mitochondrial seryl-tRNA aminoacylation
The process of coupling threonine to threonyl-tRNA in a mitochondrion, catalyzed by threonyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
mitochondrial threonyl-tRNA aminoacylation
Any process that stops, prevents, or reduces the frequency, rate or extent of enamel mineralization, the deposition of calcium salts in tooth enamel.
negative regulation of enamel mineralization
Any process that activates or increases the frequency, rate or extent of enamel mineralization, the deposition of calcium salts in tooth enamel.
positive regulation of enamel mineralization
Binding to a DNA polymerase.
DNA polymerase binding
The process of coupling tryptophan to tryptophanyl-tRNA in a mitochondrion, catalyzed by tryptophanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
mitochondrial tryptophanyl-tRNA aminoacylation
The process of coupling tyrosine to tyrosyl-tRNA in a mitochondrion, catalyzed by tyrosyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
mitochondrial tyrosyl-tRNA aminoacylation
The process of coupling valine to valyl-tRNA in a mitochondrion, catalyzed by valyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
mitochondrial valyl-tRNA aminoacylation
The controlled breakdown of a synaptonemal complex.
synaptonemal complex disassembly
A receptor complex that consists of two identical subunits and binds growth hormone.
growth hormone receptor complex
A histone deacetylase complex that is part of the chromatin remodeling machinery. In Saccharomyces cerevisiae this complex contains Snt2p, Ecm5p and Rpd3p.
Snt2C complex
A protein complex that contains the protein-tyrosine kinase CSK and the GTPase-activating protein (GAP)-associated p62 (GAP-A.p62); may mediate translocation of proteins, including GAP and CSK, to membrane or cytoskeletal regions upon c-Src activation.
CSK-GAP-A.p62 complex
Catalysis of the hydrolysis of 5'-phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between DNA topoisomerase II and DNA.
5'-tyrosyl-DNA phosphodiesterase activity
The removal of phosphoric residues from peptidyl-O-phospho-L-serine to form peptidyl-serine.
peptidyl-serine dephosphorylation
The side of the fungal-type cell wall that is opposite to the side that faces the cell and its contents.
external side of fungal-type cell wall
A transcription factor complex that is involved in regulating transcription from RNA polymerase III (Pol III) promoters. TFIIIE contains a specific subset of ribosomal proteins.
transcription factor TFIIIE complex
Binding to phosphatidylinositol-4-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' position.
phosphatidylinositol-4-phosphate binding
The metabolic process in which ammonia (NH3) is oxidized to nitrite (NO2) in the presence of oxygen. Hydroxylamine is produced enzymatically, and, in the presence of pyruvate, forms pyruvic oxime in a spontaneous, non-enzymatic reaction; pyruvic oxime is then converted to nitrite.
aerobic ammonia oxidation to nitrite via pyruvic oxime
Binding to pyridoxal, 3-hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carbaldehyde, a form of vitamin B6.
pyridoxal binding
Binding to pyridoxamine, 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, a form of vitamin B6.
pyridoxamine binding
Binding to pyridoxine, 4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol, a form of vitamin B6.
pyridoxine binding
The process whose specific outcome is the progression of a pigment cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a pigment cell fate.
pigment cell development
A protein complex that binds iron and acts as a major iron storage system. There are three major subclasses of ferritins: the classical ferritins (Ftn), the heme-containing bacterioferritins (Bfr) and the DNA-binding proteins from starved cells (Dps). Ftn and Bfr are made of 24 subunits, whereas Dps are smaller with 12 subunits. Ftn is found in most kindoms, while Bfr and Dps are restricted to prokaryotes.
ferritin complex
A nucleotide-excision repair complex formed by the association of the heterodimeric endonuclease XPF/ERCC4-ERCC1 (Rad1p and Rad10p in S. cerevisiae) with the RAD52 protein.
RAD52-ERCC4-ERCC1 complex
A protein complex formed by the association of RGS6, a negative regulator of heterotrimeric G protein signaling, with the DMAP1-Dnmt1 transcriptional repressor complex; in the complex, RGS6 inhibits the transcriptional repressor activity of DMAP1.
RGS6-DNMT1-DMAP1 complex
A cell cycle process that activates or increases the rate or extent of the transition from the G0 quiescent state to the G1 phase.
positive regulation of G0 to G1 transition
Binds to and stops, prevents, or reduces the activity of an inwardly rectifying potassium channel.
inward rectifier potassium channel inhibitor activity
A protein complex that contains the cell-surface protein CD20 and the Src family tyrosine kinases Lck and Fyn.
CD20-Lck-Fyn complex
A protein complex that contains the cell-surface protein CD20 and the Src family tyrosine kinases Lck, Lyn and Fyn.
CD20-Lck-Lyn-Fyn complex
Binding to a 3'-flap structure in DNA. A DNA flap structure is one in which a single-stranded 3'-end of DNA or RNA protrudes from a double-stranded DNA molecule.
3'-flap-structured DNA binding
Binding to a 5'-flap structure in DNA. A DNA flap structure is one in which a single-stranded 5'-end of DNA or RNA protrudes from a double-stranded DNA molecule. 5'-flap structures can be formed during DNA repair or lagging strand synthesis; in the latter case RNA flaps form from lagging strand RNA primers.
5'-flap-structured DNA binding
A protein complex that contains the zinc finger transcription factor GATA1, the LIM domain protein Lmo2 (RBTN2), the basic helix-loop-helix protein TAL1 and its binding partner TCF3. The complex is involved transcriptional regulation in hematopoiesis.
GATA1-TAL1-TCF3-Lmo2 complex
A protein complex that contains the zinc finger transcription factor GATA2, the LIM domain protein Lmo2 (RBTN2), the basic helix-loop-helix protein TAL1 and its binding partner TCF3. The complex is involved transcriptional regulation in hematopoiesis.
GATA2-TAL1-TCF3-Lmo2 complex
The removal of an amino group from a cytosine residue in DNA, forming a uracil residue.
DNA cytosine deamination
The process whose specific outcome is the progression of the Harderian gland over time, from its formation to the mature structure. The Harderian gland is an anterior orbital structure usually associated with the nictitating membrane, and produces and secretes a variety of substances to the eye, depending upon the species.
Harderian gland development
A protein complex that contains beta-glucuronidase and the carboxyl esterase egasyn; formation of the complex causes beta-glucuronidase to be retained in the endoplasmic reticulum.
egasyn-beta-glucuronidase complex
Binding to glutamine, 2,5-diamino-5-oxopentanoic acid.
glutamine binding
Binding to an inhibitory SMAD signaling protein.
I-SMAD binding
A nonhomologous end joining complex that contains one or more Ku monomers and one or more DNA ligase molecules from the LigC or LigD family, and mediates nonhomologous end joining in bacteria.
Ku-DNA ligase complex
A protein complex that contains DNA ligase III and XRCC1, and is involved in base excision repair.
DNA ligase III-XRCC1 complex
A transcriptional repressor complex that contains a heterodimer of the bHLH-ZIP proteins Mad and Max, plus mSin3A, a homolog of the yeast Sin3p.
Mad-Max-mSin3A complex
A transcriptional repressor complex that contains a heterodimer of the bHLH-ZIP proteins Mad and Max, plus mSin3B, a homolog of the yeast Sin3p.
Mad-Max-mSin3B complex
A transcriptional repressor complex that consists of a heterodimer of the bHLH-ZIP proteins Mad and Max.
Mad-Max complex
Catalysis of the reaction: D-galactose-1-phosphate + H2O = D-galactose + phosphate.
D-galactose-1-phosphate phosphatase activity
The removal of tubulin heterodimers from the plus end of a microtubule.
plus-end specific microtubule depolymerization
A protein complex that consists of an alphav-beta3 integrin complex bound to the alpha3 chain of type VI collagen; the integrin binds most strongly to unfolded collagen.
alphav-beta3 integrin-collagen alpha3(VI) complex
The addition of a methyl group to the N7 atom in the base portion of a guanine nucleotide residue in an rRNA molecule.
rRNA (guanine-N7)-methylation
An intracellular part that represents the innermost portion of an endospore; the endospore core is dehydrated, enriched in dipicolinic acid and divalent cations, and metabolically inactive.
endospore core
Catalysis of the reaction: 7,8-dihydroneopterin triphosphate + H2O = 6-carboxy-5,6,7,8-tetrahydropterin + triphosphate + acetaldehyde + 2 H+.
6-carboxy-5,6,7,8-tetrahydropterin synthase activity
A transcription factor complex that contains the serum response factor (SRF) and the basic helix-loop-helix proteins myogenin and E12, and is involved in activating transcription of muscle-specific genes.
SRF-myogenin-E12 complex
A protein complex that consists of an alpha4-beta1 integrin complex bound to membrane protein CD82, a member of the tetraspan family.
alpha4-beta1 integrin-CD82 complex