NothingMuch/GO-Terms huggingface dataset:
Binding to telethonin, a protein found in the Z disc of striated muscle and which is a substrate of the titin kinase.
telethonin binding
A heterodimeric complex comprising BRCA1 and BARD1, which possesses ubiquitin ligase activity and is involved in genome maintenance, possibly by functioning in surveillance for DNA damage.
BRCA1-BARD1 complex
An organelle consisting of a proteinaceous coat and enzymes for the fixation of CO2. It augments the concentration of CO2 in the vicinity of RuBisCO to increase the efficiency of CO2 fixation under atmospheric conditions.
carboxysome
An organelle found in bacteria consisting of a proteinaceous coat containing enzymes for the degradation of 1,2-propanediol whose purpose is the protection of the rest of the cell from the toxic propionaldehyde product of the enzyme diol dehydratase.
propanediol degradation polyhedral organelle
Binding to a class III myosin; myosin III is monomeric and has an N terminal kinase domain.
myosin III binding
A myosin complex containing one or more class IV myosin heavy chains and associated light chains; myosin IV is relatively uncharacterized, but is predicted to have a single motor domain, one IQ motif and a tail with a Myosin Tail Homology (myTH4) domain homologous to that in the tails of myosins VII and XV.
myosin IV complex
A myosin complex containing a dimer of class V myosin heavy chains and associated light chains; involved in intracellular transport. Myosin V is a dimeric molecule consisting of conserved motor domains followed by 6 IQ motifs which bind specific light chains and calmodulin. The tail domain is important for cellular localization and cargo binding and can be divided into an alpha-helical coiled coil region and a C-terminal globular region.
myosin V complex
A myosin complex containing one or more class VI myosin heavy chains and associated light chains. Myosin VI has a single IQ motif in the neck and a tail region with a coiled coil domain followed by a unique globular domain; a unique insertion that enables myosin VI to move towards the pointed or minus end of actin filaments.
myosin VI complex
A myosin complex containing a dimer of class VII myosin heavy chains and associated light chains. Myosin VII (240 kDa) is predicted to be a dimeric molecule with 5 IQ motifs and a tail region with a short stretch of coiled coil followed by two myosin-tail homology (MyTH4) domains, two talin-binding (FERM) domains and an SH3-domain.
myosin VII complex
A myosin complex containing a dimer of class VIII myosin heavy chains and associated light chains. Myosin VIII is predicted to be dimeric, and contain an unusual 100-190 residue N-terminal extension prior to their motor domains, 3-4 IQ motifs, a short region (~70 residues) of predicted alpha-helical coiled coil and a C-terminal domain.
myosin VIII complex
A myosin complex containing a class IX myosin heavy chain and associated light chains. Myosin IX is monomeric with a motor domain containing an N-terminal extension and an insert in the actin binding interface, followed by four to six IQ motifs and a tail region that contains a zinc binding motif and a domain with homology to GTPase activating proteins (GAPs) of the Rho family of G-proteins.
myosin IX complex
A myosin complex containing one or more class X myosin heavy chains and associated light chains.
myosin X complex
A myosin complex containing a dimer of class XI myosin heavy chains and associated light chains. Myosin XI heavy chain sizes are similar in molecular structure to the class V myosins with 5 to 6 IQ motifs and tail regions with predicted coiled coil domains (forming dimeric molecules) and large C-terminal regions.
myosin XI complex
A myosin complex containing one or more class XII myosin heavy chains and associated light chains; myosin XII contains a large tail region with two MyTH4 domains and a short region of coiled coil.
myosin XII complex
A myosin complex containing one or more class XIII myosin heavy chains and associated light chains.
myosin XIII complex
A myosin complex containing a class XIV myosin heavy chain and associated light chains; myosin XIV heavy chains are the simplest known, containing a motor domain, no classic IQ motif and variable length tails.
myosin XIV complex
A myosin complex containing a class XV myosin heavy chain and associated light chains. Myosin XV is single headed, and has a large extension (1200aa) at the N-terminus of the motor domain, two IQ motifs and a tail with a similar domain structure to that of the tail of myosin VII.
myosin XV complex
A myosin complex containing a class XVI myosin heavy chains and associated light chains; myosin XVI heavy chains contain ankyrin repeat.
myosin XVI complex
A myosin complex containing one or more class XVII myosin heavy chains and associated light chains.
myosin XVII complex
A myosin complex containing a class XVIII myosin heavy chain and associated light chains; myosin XVIII heavy chains contain an N-terminal PDZ domain.
myosin XVIII complex
Binding to a class V myosin; myosin V is a dimeric molecule involved in intracellular transport.
myosin V binding
Binding to the DNA portion of a nucleosome.
nucleosomal DNA binding
A high molecular weight complex characterized in S. pombe containing the cell-end anchoring protein Tea1. This complex is transported to the cell ends by microtubules and is involved in bipolar growth and the maintennce of normal cell polarity.
Tea1 cell-end complex
A protein complex involved in the catalysis of the formation of the modified nucleotide 1-methyladenosine (m1A) in tRNA. In yeast, it is a heterotetramer of two subunits, Gcd10p and Gcd14p, while in bacteria and archaea it is a homotetramer.
tRNA (m1A) methyltransferase complex
The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 730nm. The response may involve a change in conformation.
far-red light photoreceptor activity
The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 660nm. The response may involve a change in conformation.
red light photoreceptor activity
A multisubunit protein complex that binds to centromeric DNA and initiates kinetochore assembly. In yeast, this complex consists of four subunits, namely Ctf13p, Skp1p, Cep3p and Cbf2p.
CBF3 complex
Structure within the hyphal tip of filamentous fungi that acts as an organizing center for hyphal tip growth; may function to supply vesicles to the elongating tip and/or to organize cytoskeletal microfilaments.
spitzenkorper
The portion of the plasma membrane surrounding the brush border.
brush border membrane
The portion of the plasma membrane surrounding a filopodium.
filopodium membrane
A protein complex that consists of an RNA 5' triphosphatase and a guanyl transferase (Cet1p and Ceg1p in S. cerevisiae; Pct1 and Ceg1 in S. pombe) and is involved in mRNA capping.
mRNA capping enzyme complex
The movement of one microtubule along another microtubule, where the motion is directed towards the minus ends of the microtubules.
minus-end directed microtubule sliding
Protein complex that has a role in determining cell polarity, found at the neck of a fungal bud before and during cytokinesis.
cellular bud neck polarisome
Protein complex that has a role in determining cell polarity, found at the tip of a growing fungal bud.
cellular bud tip polarisome
Protein complex that has a role in determining cell polarity, found at the tip of a growing fungal hypha.
hyphal tip polarisome
Protein complex that has a role in determining cell polarity, found at the tip of the mating projection in unicellular fungi exposed to mating pheromone.
mating projection tip polarisome
Assembly of hemidesmosomes, integrin-containing protein complexes that bind to laminin in the basal lamina. Hemidesmosomes form the contact between the basal surface of epithelial cells and the underlying basal lamina.
hemidesmosome assembly
Any process that initiates the activity of inactive phospholipase D.
activation of phospholipase D activity
An amorphous structure surrounding the core of the centrosome, from which microtubules are nucleated; contains gamma-tubulin.
centrosomal corona
The subunits forming the outer ring of the core complex of a proteasome located in the nucleus of a cell.
nuclear proteasome core complex, alpha-subunit complex
The proteasome core subcomplex that constitutes the two outer rings of the cytosolic proteasome core complex.
cytosolic proteasome core complex, alpha-subunit complex
The subunits forming the inner ring of the core complex of a proteasome located in the nucleus of a cell.
nuclear proteasome core complex, beta-subunit complex
The proteasome core subcomplex that constitutes the two inner rings of the cytosolic proteasome core complex.
cytosolic proteasome core complex, beta-subunit complex
The subunits of the regulatory particle that directly associate with the core complex of a proteasome located in the nucleus of a cell.
nuclear proteasome regulatory particle, base subcomplex
The subcomplex of the proteasome regulatory particle that directly associates with the proteasome core complex located in the cytosol of the cell.
cytosolic proteasome regulatory particle, base subcomplex
The subunits that form the peripheral lid of the regulatory particle of a proteasome located in the nucleus of a cell.
nuclear proteasome regulatory particle, lid subcomplex
The subcomplex of the cytosolic proteasome regulatory particle that forms the peripheral lid, which is added on top of the base subcomplex.
cytosolic proteasome regulatory particle, lid subcomplex
A centrosome from which one pole of a mitotic or meiotic spindle is organized.
spindle pole centrosome
Binding to a ubiquitin conjugating enzyme, any of the E2 proteins.
ubiquitin conjugating enzyme binding
Binding to beta-endorphin, a peptide generated by the cleavage of pro-opiomelanocortin.
beta-endorphin binding
A chromatophore containing yellow pigment.
xanthophore
Binding to a complex of G-protein beta/gamma subunits.
G-protein beta/gamma-subunit complex binding
Binding to a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex.
haptoglobin binding
Binding to a hemoglobin alpha chain.
hemoglobin alpha binding
Binding to a hemoglobin beta chain.
hemoglobin beta binding
A protein complex formed by the stable binding of a haptoglobin to hemoglobin.
haptoglobin-hemoglobin complex
The inner, i.e. lumen-facing, lipid bilayer of the chromoplast envelope; also faces the chromoplast stroma.
chromoplast inner membrane
The outer, i.e. cytoplasm-facing, lipid bilayer of the chromoplast envelope.
chromoplast outer membrane
The volume enclosed by the membrane of an early endosome.
early endosome lumen
The volume enclosed by the membranes of a glyoxysome.
glyoxysomal lumen
Stable, specialized structure for the ingestion of food by the cell into phagosomes.
cytostome
Stable, specialized structure for extrusion of waste by the cell into the surrounding medium.
cytoproct
Stable structure that regulates the flow of liquid between the contractile vacuole and the surrounding medium.
contractile vacuole pore
The directed movement of pyridoxal phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore; pyridoxal phosphate is pyridoxal phosphorylated at the hydroxymethyl group of C-5, and is the active form of vitamin B6.
pyridoxal phosphate transport
Enables the transfer of pyridoxal phosphate from one side of a membrane to the other. Pyridoxal phosphate is pyridoxal phosphorylated at the hydroxymethyl group of C-5, and is the active form of vitamin B6.
pyridoxal phosphate transmembrane transporter activity
Enables the transfer of pyridoxamine from one side of a membrane to the other. Pyridoxamine, 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.
pyridoxamine transmembrane transporter activity
Heterochromatic regions of the chromosome found at silenced mating-type loci.
mating-type region heterochromatin
Protease complex of the mitochondrial inner membrane whose catalytic residues lie on the intermembrane space side of the inner membrane; involved in mitochondrial protein turnover. Contains a subunit belonging to the AAA family of ATP-dependent metalloproteases.
i-AAA complex
A leucoplast in which protein is stored.
proteinoplast
Absorbing energy from one or more photons and transferring their energy to another molecule, usually a protein, within the cell.
light transducer activity
The covalent addition to a protein of ISG15, a ubiquitin-like protein.
ISG15-protein conjugation
Binding to a light chain of a myosin I complex.
myosin I light chain binding
Binding to the head/neck region of a myosin I heavy chain.
myosin I head/neck binding
Binding to the tail region of a myosin I heavy chain.
myosin I tail binding
Binding to a light chain of a myosin II complex.
myosin II light chain binding
Binding to the head/neck region of a myosin II heavy chain.
myosin II head/neck binding
Binding to the tail region of a myosin II heavy chain.
myosin II tail binding
A protein complex that stably associates with the C-terminus of RNA polymerase II and mediates 3'-end processing of small nuclear RNAs generated by RNA polymerase II.
integrator complex
Binding to a clathrin heavy chain.
clathrin heavy chain binding
Binding to a clathrin light chain.
clathrin light chain binding
Binding to a NACHT (NAIP, CIITA, HET-E and TP1) domain. The NACHT domain consists of seven distinct conserved motifs, including an ATP/GTPase specific P-loop, a Mg2+-binding site and five more specific motifs.
NACHT domain binding
Any process that modulates the frequency, rate or extent of protein histidine kinase activity.
regulation of protein histidine kinase activity
The process of binding or confining zinc ions such that they are separated from other components of a biological system.
sequestering of zinc ion
Binding to an O6-alkylguanine adduct in DNA.
O6-alkylguanine-DNA binding
Binding to a double-stranded DNA region containing a single adenine insertion or a deletion that results in an unpaired adenine.
single adenine insertion binding
Binding to a double-stranded DNA region containing a single cytosine insertion or a deletion that results in an unpaired cytosine.
single cytosine insertion binding
Binding to a double-stranded DNA region containing a single guanine insertion or a deletion that results in an unpaired guanine.
single guanine insertion binding
Binding to a double-stranded DNA region containing a single thymine insertion or a deletion that results in an unpaired thymine.
single thymine insertion binding
The chemical reactions and pathways resulting in the formation of ubiquinone, beginning with the conversion of chorismate to 4-hydroxybenzoate.
ubiquinone biosynthetic process from chorismate
A heterooligomeric septin complex that acts during mitotic cell division.
mitotic septin complex
A heterooligomeric septin complex that acts during meiotic cell division.
meiotic septin complex
A septin band, i.e. a diffuse ring composed of a series of septin bars running parallel to the long axis of the cell, located at the neck of a shmoo (mating projection).
mating projection septin band
A septin band, i.e. a diffuse ring composed of a series of septin bars running parallel to the long axis of the cell, located at the junction between the mother cell and the germ tube (hypha) of a fungal cell growing filamentously.
hyphal septin band
A faint structure formed of septins found at the leading edge of growth in hyphae of fungal cells growing filamentously. This cap of septins colocalizes with a region of the plasma membrane that is rich in ergosterol.
hyphal septin cap
Arrays of septin filaments, or bars, found in a series of filamentous structures; observed in the prospore membrane during spore formation.
prospore septin filament array
Arrays of septin filaments, or bars, found in a series of filamentous structures. Observed in the chlamydospore membrane during chlamydospore formation.
chlamydospore septin filament array
A tight ring-shaped structure that forms in the division plane within hyphae of filamentous fungi at sites where a septum will form; composed of septins as well as septin-associated proteins.
hyphal septin ring
A tight ring-shaped structure that forms in the division plane at the site of cytokinesis in a prospore; composed of septins as well as septin-associated proteins.
prospore septin ring
A tight ring-shaped structure that forms in the division plane at the junction between the mother cell and a pseudohyphal projection; composed of septins as well as septin-associated proteins.
pseudohyphal septin ring
A faint structure formed of septins found at the leading edge of growth in germ tubes of fungal cells growing filamentously. This cap of septins colocalizes with a region of the plasma membrane that is rich in ergosterol.
germ tube septin cap
A tight ring-shaped structure that forms in the division plane within the germ tube of filamentous fungi at sites where a septum will form; composed of septins as well as septin-associated proteins.
germ tube septin ring
A tubular structure with flared ends, shaped like an hourglass and composed of highly ordered arrays of septin filaments, that forms at the bud neck of a dividing cell. In S. cerevisiae, this structure is located at the bud neck throughout most of the cell cycle and the septins are fixed within the structure, not exchanging with soluble septins. This septin structure acts as a scaffold for other proteins that function at the bud neck.
cellular bud neck septin collar
A septin ring, i.e. a ring-shaped structure composed of septins and septin-associated proteins, located at the neck of a shmoo (mating projection). The septin ring in the neck of a shmoo may act as a barrier to localize mating factors in the shmoo tip.
mating projection septin ring
Two separate septin rings that are formed from the septin collar at the time of cytokinesis in cells that divide by budding. These two rings are thought to delineate a special compartment in which factors involved in cytokinesis are concentrated.
cellular bud neck split septin rings
The chemical reactions and pathways resulting in the formation of ubiquinone, beginning with the conversion of tyrosine to 4-hydroxybenzoate.
ubiquinone biosynthetic process from tyrosine
Binding to a double-stranded DNA region containing a dinucleotide repeat insertion or a deletion resulting in unpaired dinucleotide repeats.
dinucleotide repeat insertion binding
The chemical reactions and pathways resulting in the formation of ubiquinone, via the intermediates 2-polyprenylphenol and 2-polyprenyl-6-hydroxyphenol.
ubiquinone biosynthetic process via 2-polyprenylphenol
The chemical reactions and pathways resulting in the formation of ubiquinone, via the intermediates 3,4-dihydroxy-5-polyprenylbenzoate and 3-methoxy-4-hydroxy-5-polyprenylbenzoate.
ubiquinone biosynthetic process via 3,4-dihydroxy-5-polyprenylbenzoate
A cellular process that results in the formation of a telomere at a non-telomeric double-stranded DNA end that involves the activity of a telomerase enzyme.
telomere formation via telomerase
The directed movement of riboflavin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Riboflavin (vitamin B2) is a water-soluble B-complex vitamin, converted in the cell to FMN and FAD, cofactors required for the function of flavoproteins.
riboflavin transport
A process that initiates the activity of an inactive store-operated calcium channel.
activation of store-operated calcium channel activity
Any process that modulates the frequency, rate or extent of the directed movement of a pyrimidine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
regulation of pyrimidine nucleoside transport
Any process which produces guanosine monophosphate from derivatives of it, without de novo synthesis.
GMP salvage
Any process which produces inosine monophosphate from derivatives of it, without de novo synthesis.
IMP salvage
Any process which produces xanthosine monophosphate from derivatives of it, without de novo synthesis.
XMP salvage
An acetate CoA-transferase complex located in the stroma of a plastid.
plastid acetate CoA-transferase complex
The process in which satellite glial cells isolate neuronal cell bodies.
ensheathment of neuronal cell bodies
The chemical reactions and pathways resulting in the breakdown of aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance.
aldosterone catabolic process
The chemical reactions and pathways resulting in the breakdown of pyridoxal phosphate, pyridoxal phosphorylated at the hydroxymethyl group of C-5, the active form of vitamin B6.
pyridoxal phosphate catabolic process
The chemical reactions and pathways resulting in the breakdown of FMN, riboflavin 5'-(dihydrogen phosphate), a coenzyme for a number of oxidative enzymes including NADH dehydrogenase.
FMN catabolic process
A transmembrane protein complex composed of a MHC class Ib alpha chain and, in most cases, an invariant beta2-microglobin chain, and with or without a bound peptide or lipid antigen. Class Ib here refers to non-classical class I molecules, such as those of the CD1 or HLA-E gene families.
MHC class Ib protein complex
Binding to a HECT, 'Homologous to the E6-AP Carboxy-Terminus', domain of a protein.
HECT domain binding
Binding to a MutLalpha mismatch repair complex.
MutLalpha complex binding
Binding to a MutLbeta mismatch repair complex.
MutLbeta complex binding
Binding to a MutSalpha mismatch repair complex.
MutSalpha complex binding
Binding to a MutSbeta mismatch repair complex.
MutSbeta complex binding
A distinct compartment at the tip of a stereocilium, distal to the site of attachment to the apical cell surface. It consists of a dense matrix bridging the barbed ends of the stereocilium actin filaments with the overlying plasma membrane, is dynamic compared to the shaft, and is required for stereocilium elongation.
stereocilium tip
Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-galactosamine residues in N-acetyl-beta-D-galactosaminides.
beta-N-acetylgalactosaminidase activity
The end of a filopodium distal to the body of the cell.
filopodium tip
A dense network of actin filaments found beneath the apical cell surface of hair cells, and into which stereocilia are inserted.
cuticular plate
Catalysis of the reaction: pheophorbide a + reduced ferredoxin + 2 O2 = red chlorophyll catabolite + oxidized ferredoxin + H2O.
pheophorbide a oxygenase activity
Covalent attachment of the ubiquitin-like protein URM1 to another protein.
protein urmylation
Binding to a DNA region containing a hairpin. A hairpin structure forms when a DNA strand folds back on itself and intrachain base pairing occurs between inverted repeat sequences.
DNA hairpin binding
The directed movement of membrane-bounded vesicles from deep (non-peripheral) compartments endocytic compartments back to the plasma membrane where they are recycled for further rounds of transport.
slow endocytic recycling
Any process that modulates the frequency, rate or extent of Rab protein signal transduction.
regulation of Rab protein signal transduction
Any process that modulates the frequency, rate or extent of Ral protein signal transduction.
regulation of Ral protein signal transduction
Any process that modulates the frequency, rate or extent of Rap protein signal transduction.
regulation of Rap protein signal transduction
Any process that modulates the frequency, rate or extent of Cdc42 protein signal transduction.
regulation of Cdc42 protein signal transduction
The series of events in which a muramyl dipeptide stimulus is received by a cell and converted into a molecular signal. Muramyl dipeptide is derived from peptidoglycan.
detection of muramyl dipeptide
Interacting selectively and non-covalently, in a non-covalent manner, with muramyl dipeptide; muramyl dipeptide is derived from peptidoglycan.
muramyl dipeptide binding