NothingMuch/GO-Terms huggingface dataset:
The process whose specific outcome is the progression of the superior salivary nucleus over time, from its formation to the mature structure.
superior salivary nucleus development
The process whose specific outcome is the progression of the facial nucleus over time, from its formation to the mature structure.
facial nucleus development
The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature eurydendroid cell. Differentiation includes the processes involved in commitment of a neuroblast to a eurydendroid cell fate. A eurydendroid cell is an efferent neuron found in the cerebellar cortex of teleosts.
eurydendroid cell differentiation
The progression of the caudate nucleus over time from its initial formation until its mature state. The caudate nucleus is the C-shaped structures of the striatum containing input neurons involved with control of voluntary movement in the brain.
caudate nucleus development
The progression of the putamen over time from its initial formation until its mature state. The putamen is the lens-shaped basal ganglion involved with control of voluntary movement in the brain.
putamen development
The progression of the substantia nigra over time from its initial formation until its mature state. The substantia nigra is the layer of gray substance that separates the posterior parts of the cerebral peduncles (tegmentum mesencephali) from the anterior parts; it normally includes a posterior compact part with many pigmented cells (pars compacta) and an anterior reticular part whose cells contain little pigment (pars reticularis).
substantia nigra development
The progression of the amygdala over time from its initial formation until its mature state. The amygdala is an almond-shaped set of neurons in the medial temporal lobe of the brain that play a key role in processing emotions such as fear and pleasure.
amygdala development
The progression of the cingulate gyrus over time from its initial formation until its mature state. The cingulate gyrus is a ridge in the cerebral cortex located dorsal to the corpus callosum.
cingulate gyrus development
The process whose specific outcome is the progression of the postganglionic portion of the parasympathetic fiber over time, from its formation to the mature structure. The parasympathetic fiber is one of the two divisions of the vertebrate autonomic nervous system. Parasympathetic nerves emerge cranially as pre ganglionic fibers from oculomotor, facial, glossopharyngeal and vagus and from the sacral region of the spinal cord. Most neurons are cholinergic and responses are mediated by muscarinic receptors. The parasympathetic system innervates, for example: salivary glands, thoracic and abdominal viscera, bladder and genitalia.
postganglionic parasympathetic fiber development
The extension of a long process to the pial surface as a cell leaves the ventricular zone.
extension of leading cell process to pial surface
The rearrangements of the microtubule cytoskeleton that result in the extension of a leading process, where this process is involved in the movement of cells along radial glial cells.
extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration
The movement of cerebral cortex neuronal precursors tangentially through the cortex using interaction of the migrating cells with axons of other neurons.
cerebral cortex tangential migration using cell-axon interactions
The directed movement of oligodendrocytes from the subpallium to the cerebral cortex during forebrain development.
oligodendrocyte cell migration from the subpallium to the cortex
The attachment of cells to one another to form groups of cells involved in cerebral cortex tangential migration.
cell-cell adhesion involved in cerebral cortex tangential migration using cell-cell interactions
The interaction of a cell and the extracellular matrix involved in the directed tangential movement of cells mediated by cell-cell interactions in the developing cerebral cortex.
cell-matrix adhesion involved in tangential migration using cell-cell interactions
The process in which migrating interneurons interact with an external substratum as a component of migration from the subpallium to the cortex.
interneuron-substratum interaction involved in interneuron migration from the subpallium to the cortex
The establishment and response to guidance cues that distribute interneurons to different cerebral cortex structures.
interneuron sorting involved in substrate-independent cerebral cortex tangential migration
The response of migrating interneurons to neurotransmitters that alter electrical activity in cells in calcium dependent manner.
neurotransmitter-mediated guidance of interneurons involved in substrate-independent cerebral cortex tangential migration
The division of neuroblasts in the subventricular zone of the forebrain. The interneuron precursors that these cells give rise to include adult olfactory bulb interneurons and migrate tangentially.
neuroblast division in subventricular zone
The division of neuroblasts in the dorsal region of the lateral ganglionic eminence. These cells give rise to embryonic interneuron precursors that will migrate tangentially to the olfactory bulb.
neuroblast division in dorsal lateral ganglionic eminence
The migration of GABAergic interneuron precursors from the subpallium to the cerebral cortex.
cerebral cortex GABAergic interneuron migration
The process in which a neuroblast acquires the specialized structural and functional features of a GABAergic inhibitory neuron in the basal ganglia. Differentiation includes the processes involved in commitment of a neuroblast to a GABAergic neuron.
GABAergic neuron differentiation in basal ganglia
The process in which a neuroblast acquires specialized structural and/or functional features of a Cajal-Retzius cell, one of a transient population of pioneering neurons in the cerebral cortex. These cells are slender bipolar cells of the developing marginal zone. One feature of these cells in mammals is that they express the Reelin gene.
Cajal-Retzius cell differentiation
The process in which the developmental fate of a cell becomes restricted such that it will develop into an astrocyte that resides in the forebrain.
forebrain astrocyte fate commitment
The process in which the developmental fate of a neuroblast becomes restricted such that it will develop into an interneuron residing in the olfactory bulb.
olfactory bulb interneuron fate commitment
The process in which the developmental fate of a neuroblast becomes restricted such that it will develop into a GABAergic interneuron residing in the cerebral cortex.
cerebral cortex GABAergic interneuron fate commitment
The process aimed at the progression of an astrocyte that resides in the forebrain, from initial commitment of the cell to its fate, to the fully functional differentiated cell. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function.
forebrain astrocyte development
The commitment of neuroblast to become a basal progenitor cell. Basal progenitor cells are neuronal precursor cells that are committed to becoming neurons.
ventricular zone cell fate commitment
The commitment of neuroepithelial cell to become a neuron that will reside in the forebrain.
early neuron fate commitment in forebrain
The commitment of neuronal precursor cells to become specialized types of neurons in the forebrain.
commitment of neuronal cell to specific neuron type in forebrain
The process whose specific outcome is the creation of the forebrain-midbrain boundary.
forebrain-midbrain boundary formation
The process whose specific outcome is the formation of the hindbrain-spinal cord boundary.
hindbrain-spinal cord boundary formation
The multiplication or reproduction of neuroblasts that will give rise to Purkinje cells. A Purkinje cell is an inhibitory GABAergic neuron found in the cerebellar cortex that projects to the deep cerebellar nuclei and brain stem.
cerebellar Purkinje cell precursor proliferation
The multiplication or reproduction of neuroblasts that will give rise to Golgi cells. A Golgi cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.
Golgi cell precursor proliferation
The multiplication or reproduction of neuroblasts that will give rise to deep nuclear neurons.
deep nuclear neuron precursor proliferation
The multiplication or reproduction of neuroblasts that will give rise to basket cells. A cerebellar basket cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.
basket cell precursor proliferation
The multiplication or reproduction of neuroblasts that will give rise to stellate cells. A cerebellar stellate cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.
stellate cell precursor proliferation
The multiplication or reproduction of neuroblasts that will give rise to neurons of the lateral pontine nucleus and the locus ceruleus.
rostral hindbrain neuronal precursor cell proliferation
The inward migration of postmitotic granule cells along a radial glial cell from the external granule layer to the internal granule cell layer.
radial glia guided migration of cerebellar granule cell
The early migration of granule cell precursors in which cells move orthogonal to the direction of radial migration and ultimately cover the superficial zone of the cerebellar primordium.
cerebellar granule cell precursor tangential migration
The migration of postmitotic a Purkinje cell along radial glial cells from the ventricular zone to the Purkinje cell layer.
radial glia guided migration of Purkinje cell
The changes in adhesion between a neuronal cell and a glial cell as a component of the process of hindbrain glial-mediated radial cell migration.
neuronal-glial interaction involved in hindbrain glial-mediated radial cell migration
The directed movement of a deep nuclear neuron from their ventrolateral origin to a rostrodorsal region of the cerebellar plate.
outward migration of deep nuclear neurons
The directed movement of a deep nuclear neuron from the rostrodorsal region of the cerebellar plate to their final more ventral position.
inward migration of deep nuclear neurons
Generation of a long process that carries efferent (outgoing) action potentials from the cell body towards target cells from a neuron located in the central nervous system whose axons remain within a single brain region.
central nervous system interneuron axonogenesis
Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in one half of the cerebral cortex towards target cells in the contralateral half. This axonal process is a member of those that make up the anterior commissure, a small midline fiber tract that lies at the anterior end of the corpus callosum.
anterior commissure morphogenesis
Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the midbrain towards target cells in the diencephalon.
posterior commissure morphogenesis
Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the vestibular nucleus of the pons towards target cells in the spinal cord.
vestibulospinal tract morphogenesis
Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the red nucleus of the midbrain towards target cells in the spinal cord.
rubrospinal tract morphogenesis
The process in which the anatomical structures of the spinal cord ventral commissure are generated and organized.
spinal cord ventral commissure morphogenesis
The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed to cross the midline to the contralateral side.
corticospinal neuron axon decussation
Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in spinal cord towards target cells in the thalamus. This axonal process is a member of those that make up the trigeminothalamic tract, one of the major routes of nociceptive and temperature signaling from the face.
trigeminothalamic tract morphogenesis
Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the pons towards target cells in the spinal cord.
pons reticulospinal tract morphogenesis
Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the medulla towards target cells in the spinal cord.
medulla reticulospinal tract morphogenesis
Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the superior colliculus of the midbrain towards target cells in the ventral spinal cord.
tectospinal tract morphogenesis
The migration of cells in the developing subpallium in which cells move from the ventricular and/or subventricular zone toward the surface of the brain.
subpallium radially oriented migration
The progression of the habenula over time from its initial formation until its mature state. The habenula is the group of nuclei that makes up the stalk of the pineal gland.
habenula development
The progression of the olfactory cortex over time from its initial formation until its mature state. The olfactory cortex is involved in the perception of smell. It receives input from the olfactory bulb and is responsible for the identification of odors.
olfactory cortex development
The process of apical-basal elongation of individual ectodermal cells during the formation of the neural placode.
neural plate thickening
The process of expansion of cell numbers in the neural plate due to cell division of progenitor cells preferentially in the rostrocaudal direction, resulting in the elongation of the tissue.
cell proliferation involved in neural plate elongation
The process in which closure points are established at multiple points and along the neural rostrocaudal axis.
initiation of neural tube closure
The process in which the neural folds are fused extending from the initial closure points.
progression of neural tube closure
The process in which the anterior-most portion of the neural axis is formed by closure of the anterior neuropore.
lamina terminalis formation
The close range interaction of the anterior neural ridge to the caudal region of the neural plate that specifies the forebrain fate.
forebrain induction by the anterior neural ridge
A developmental process occurring after the brain has been specified along the neural axis that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.
midbrain-hindbrain boundary maturation during brain development
The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes in the central nervous system. The capillary endothelial cells in the brain are specialized to form the blood-brain barrier.
central nervous system vasculogenesis
The division of a radial glial cell in the pallium. A radial glial cell is a precursor cell that gives rise to neurons and astrocytes.
radial glial cell division in pallium
The division of neuroblasts in the pallium. Neuroblasts are precursor cells that give rise to neurons.
neuroblast division in pallium
The multiplication or reproduction of dorsal lateral ganglionic eminence cells, resulting in the expansion of the cell population.
dorsal lateral ganglionic eminence cell proliferation
The multiplication or reproduction of medial ganglionic eminence cells, resulting in the expansion of a cell population.
medial ganglionic eminence cell proliferation
The multiplication or reproduction of caudal ganglionic eminence cells, resulting in the expansion of a cell population.
caudal ganglionic eminence cell proliferation
The process in which the developmental fate of a cell becomes restricted such that it will develop into a radial glial cell in the forebrain.
radial glial cell fate commitment in forebrain
The movement of the nucleus of the ventricular zone cell between the apical and the basal zone surfaces. Mitosis occurs when the nucleus is near the apical surface, that is, the lumen of the ventricle.
interkinetic nuclear migration
The orderly movement of an astrocyte cell through the telencephalon.
telencephalon astrocyte cell migration
The multiplication or reproduction of telencephalon oligodendrocyte cells, resulting in the expansion of a cell population.
telencephalon oligodendrocyte cell migration
The orderly movement of microglial cells through the telencephalon.
telencephalon microglial cell migration
The multiplication or reproduction of rhombomere cells, resulting in the expansion of the cell population.
rhombomere cell proliferation
The movement of a cell within a rhombomere. This process is known to occur as an early step in the generation of anatomical structure from a rhombomere.
rhombomere cell migration
The process in which a relatively unspecialized cell acquires specialized features of a rhombomere cell.
rhombomere cell differentiation
The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that results in the attainment of the full functional capacity of a protein.
protein maturation by protein folding
The process in which a relatively unspecialized cell acquires specialized features of a generative cell. The generative cell gives rise to the sperm cells in the male gametophyte.
generative cell differentiation
Catalysis of the active transport of a sodium ion across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged.
sodium ion uniporter activity
Catalysis of the active transport of a potassium ion across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged.
potassium ion uniporter activity
Enables the transport of a potassium ion across a membrane via a narrow pore channel that is open even in an unstimulated or 'resting' state.
potassium ion leak channel activity
Enables the transmembrane transfer of a calcium ion by a channel that opens when glutamate has been bound by the channel complex or one of its constituent parts.
glutamate-gated calcium ion channel activity
Enables the transmembrane transfer of a chloride ion by a channel that opens when GABA has been bound by the channel complex or one of its constituent parts.
GABA-gated chloride ion channel activity
Enables the transmembrane transfer of a chloride ion by a channel that opens when glycine has been bound by the channel complex or one of its constituent parts.
glycine-gated chloride ion channel activity
The signaling process in which T cell signal transduction is brought to an end rather than being reversibly modulated.
termination of T cell signal transduction
Binding to a major histocompatibility complex class I molecules via the antigen binding groove.
MHC class I protein binding, via antigen binding groove
Binding to a major histocompatibility complex class I molecules via the lateral surface.
MHC class I protein binding, via lateral surface
Binding to a major histocompatibility complex class Ib molecules via the antigen binding groove.
MHC class Ib protein binding, via antigen binding groove
Binding to a major histocompatibility complex class Ib molecules via the lateral surface.
MHC class Ib protein binding, via lateral surface
The core of the CCR4-NOT complex. In Saccharomyces the CCR4-NOT core complex comprises Ccr4p, Caf1p, Caf40p, Caf130p, Not1p, Not2p, Not3p, Not4p, and Not5p.
CCR4-NOT core complex
Assembly of the parallel bundle of actin filaments at the core of a microvillus.
microvillar actin bundle assembly
The severing of actin filaments into numerous short fragments, usually mediated by actin severing proteins.
actin filament fragmentation
The formation of mature insulin by proteolysis of the precursor preproinsulin. The signal sequence is first cleaved from preproinsulin to form proinsulin; proinsulin is then cleaved to release the C peptide, leaving the A and B chains of mature insulin linked by disulfide bridges.
insulin processing
A pigment protein complex that forms part of the photosystem I associated light-harvesting complex I; contains two proteins (usually about 24 and 21.5 kDa); has a fluorescence maximum between 680 and 690 nm.
PSI associated light-harvesting complex I, LHCIa subcomplex
A pigment protein complex that forms part of the photosystem I associated light-harvesting complex I; contains two proteins (usually about 20 kDa); has a fluorescence maximum of 730 nm.
PSI associated light-harvesting complex I, LHCIb subcomplex
A pigment protein complex that forms part of the photosystem II associated light-harvesting complex II; contains two proteins (usually about 28 and 27 kDa), and may contain a third; peripherally located relative to other LHC polypeptides.
PSII associated light-harvesting complex II, peripheral complex, LHCIIb subcomplex
Any of the granules, approximately 32 nm x 48 nm and consisting of highly aggregated phycobiliproteins, that are attached in arrays to the external face of a thylakoid membrane in algae of the phyla Cyanophyta and Rhodophyta, where they function as light-harvesting devices in photosynthesis. Excitation energy in the phycobilisome flows in the sequence: phycoerythrin, phycocyanin, allophycocyanin before passing to the antenna chlorophyll of photosystem II.
phycobilisome
Photosystem located in the chloroplast that functions as a light-dependent plastocyanin-ferredoxin oxidoreductase, transferring electrons from plastocyanin to ferredoxin. An example of this is found in Arabidopsis thaliana.
chloroplast photosystem I
An integral chloroplast membrane complex containing the P680 reaction center. In the light, PSII functions as a water-plastoquinone oxidoreductase, transferring electrons from water to plastoquinone.
chloroplast photosystem II
Combining with a MHC class I molecule of the HLA-A subclass to mediate signaling that inhibits activation of a lymphocyte.
HLA-A specific inhibitory MHC class I receptor activity
Combining with a MHC class I molecule of the HLA-A subclass to mediate signaling that activates a lymphocyte.
HLA-A specific activating MHC class I receptor activity
Combining with a MHC class I molecule of the HLA-B subclass to mediate signaling that inhibits activation of a lymphocyte.
HLA-B specific inhibitory MHC class I receptor activity
Combining with a MHC class I molecule of the HLA-C subclass to mediate signaling that inhibits activation of a lymphocyte.
HLA-C specific inhibitory MHC class I receptor activity
A slime layer is an easily removed, diffuse, unorganized layer of extracellular material that surrounds a cell. Specifically this consists mostly of exopolysaccharides, glycoproteins, and glycolipids.
slime layer
A crystalline protein layer surrounding some bacteria.
S-layer
A heterotetrameric AP-type membrane coat adaptor complex that consists of beta3, delta, mu3 and sigma3 subunits and is found associated with endosomal membranes. AP-3 does not appear to associate with clathrin in all organisms. In at least humans, the AP-3 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (beta3A and beta3B, mu3A and mu3B, and sigma3A and sigma3B).
AP-3 adaptor complex
An AP-type membrane coat adaptor complex that consists of beta4, epsilon, mu4 and sigma4 subunits and is found associated with membranes in the trans-Golgi network; it is not clear whether AP-4 forms clathrin coats in vivo.
AP-4 adaptor complex