NothingMuch/GO-Terms huggingface dataset:
A cell wall part that is the part of a wall of a vessel member and bears one or more openings (perforations).
perforation plate
Any cell wall polysaccharide catabolic process that is involved in abscission.
cell wall polysaccharide catabolic process involved in abscission
Combining with the biogenic amine trimethylamine to initiate a change in cell activity.
trimethylamine receptor activity
A protein complex that inhibits unwinding of DNA at the origin of replication and assembly of the pre-primosome. In E. coli, this complex is composed of DnaA and of the ribosomal protein L2.
DnaA-L2 complex
A protein complex that inactivates the function of DnaA by inhibiting the phosphorylation of DnaA-ADP to DnaA-ATP and thereby preventing multiple events of replication initiation. In E. coli, this complex is composed of DnaA and Hda.
DnaA-Hda complex
A protein complex that negatively regulates strand-opening at the origin of replication, thereby interfering with replication initiation. This complex is thought to be involved in the regulation of replication under oxidative stress conditions. In E. coli, this complex is composed of DnaA and Dps.
DnaA-Dps complex
Any apoptotic process in a lens fiber cell. Lens fiber cells are elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye.
lens fiber cell apoptotic process
The sodium-dependent hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds.
sodium-dependent self proteolysis
The calcium-dependent hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds.
calcium-dependent self proteolysis
A protein deubiquitination process in which a linear polymer of ubiquitin, formed by the amino-terminal methionine (M1) of one ubiquitin molecule and by the carboxy-terminal glycine (G76) of the next, is removed from a protein.
protein linear deubiquitination
The process by which a callus is formed at a wound site. A plant callus is a portion of plant tissue that consists of mass of undifferentiated plant cells. It consists primarily of parenchyma cells but possibly contains other cell types as the callus begins to differentiate.
callus formation
A proteasome specifically found in mammalian testis. Contains the proteasome activator PA200 in the regulatory particle, and beta1i, beta2i, beta5i and/or alpha4s in the core (20S) subunit. Beta1i, beta2i and beta5i are inducible catalytic subunits, closely related to beta1, beta2 and beta5. Alpha4s is a sperm-specific 20S subunit, but unlike other alternative 20S subunits alpha4s lies in the outer alpha-ring and lacks catalytic activity.
spermatoproteasome complex
A heterodimer GTPase complex. In S. cerevisiae, this complex contains Gtr1p and Gtr2p proteins.
Gtr1-Gtr2 GTPase complex
An apoptotic process in a palatal shelf epithelial cell that contributes to the shaping of the palatal shelf.
epithelial cell apoptotic process involved in palatal shelf morphogenesis
Catalysis of the reaction: a flavonoid + 3'-phosphoadenosine-5'-phosphosulfate = sulfated flavonoid + adenosine-3',5'-diphosphate. This reaction is the transfer of a sulfate group to the hydroxyl group of a flavonoid acceptor, producing the sulfated flavonoid derivative.
flavonoid sulfotransferase activity
A process in which a protein is transported to, or maintained in, a location within the nuclear periphery.
protein localization to nuclear periphery
Suppression of the occurrence of translational errors, such as codon-anticodon mis-paring, during the process of translation of a protein using an mRNA template.
maintenance of translational fidelity
A process in which a protein is transported to, or maintained in, a location within a rhabdomere.
protein localization to rhabdomere
Binding to a talin, a family of related cytoskeletal proteins that play a role in assembly of actin filaments and migration of various cell types.
talin binding
A protein-DNA complex consisting of the helicase loading complex DnaB-DnaC bound to the DNA-bound DNA replication initiation protein DnaA. Essential for DNA replication initiation.
DnaA-DnaB-DnaC complex
A protein deubiquitination process in which a K27-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 27 of the ubiquitin monomers, is removed from a protein.
protein K27-linked deubiquitination
A protein deubiquitination process in which a K33-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 33 of the ubiquitin monomers, is removed from a protein.
protein K33-linked deubiquitination
The disaggregation of the SCF ubiquitin ligase complex in response to cadmium stress.
SCF complex disassembly in response to cadmium stress
Binding to an EH domain of a protein. The EH stand for Eps15 homology. This was originally identified as a motif present in three copies at the NH2-termini of Eps15 and of the related molecule Eps15R.
EH domain binding
A heteromeric protein complex consisting of a multi-transmembrane spanning subunit (the light chain) and a type II glycoprotein subunit (the heavy chain) that functions to transport amino acids across a plasma membrane.
amino acid transport complex
Any process that modulates the extent to which lymphatic vessels can be pervaded by fluid.
regulation of lymphatic vascular permeability
Binding to euchromatin, a dispersed and relatively uncompacted form of chromatin.
euchromatin binding
Catalysis of the reaction: acetyl-CoA + N-terminal L-seryl- = CoA + H+ + N-terminal Nalpha-acetyl-L-seryl-.
peptide-serine-alpha-N-acetyltransferase activity
Catalysis of the reaction: acetyl-CoA + N-terminal L-glutamate in peptide = CoA + N-acetyl-L-glutamate-peptide.
peptide-glutamate-alpha-N-acetyltransferase activity
Narrow, electron-dense part of the rhoptry that extends through the conoid at the apical tip of an apicomplexan parasite. The rhoptry neck serves as a duct through which the contents of the rhoptry are secreted after attachment to the host has been completed and at the commencement of invasion.
rhoptry neck
Binding to a histone methyltransferase enzyme.
histone methyltransferase binding
The directed movement of the proteasome core complex (AKA core particle (CP)) from the cytoplasm into the nucleus.
proteasome core complex import into nucleus
A heterodimeric transcription factor complex composed of the bZIP proteins atf1 and pcr1. The heterodimer binds m26 sites (homologous to CRE).
atf1-pcr1 complex
A protein complex that is capable of identifying lesions in DNA on the actively transcribed strand of the DNA duplex as well as a small subset of lesions not recognized by the general nucleotide-excision repair pathway. The wide range of substrate specificity suggests that the repair complex recognizes distortions in the DNA helix. It subsequently recruits a nucleotide-excision repair, preincision complex.
transcription-coupled nucleotide-excision repair, DNA damage recognition complex
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of leucine.
cellular response to leucine starvation
Binding to a keratin filament, an intermediate filament composed of acidic and basic keratins (types I and II), typically expressed in epithelial cells.
keratin filament binding
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a subsynaptic reticulum. A subsynaptic reticulum is an elaborate tubulolamellar membrane system that underlies the postsynaptic cell membrane.
subsynaptic reticulum organization
Any peptidyl-tyrosine dephosphorylation that is involved in inactivation of protein kinase activity.
peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gold nanoparticle stimulus.
response to gold nanoparticle
Combining with anti-Mullerian hormone to initiate a change in cell activity.
anti-Mullerian hormone receptor activity
Binding to a preribosome.
preribosome binding
Protein complex that associates with the kinetochores.
bub1-bub3 complex
A cellular protein complex localization that acts on a Bub1-Bub3 complex; as a result, the complex is transported to, or maintained in, a specific location at the kinetochore.
Bub1-Bub3 complex localization to kinetochore
A ubiquitin ligase complex consisting of MUB1, RAD6 and UBR2 components. It ubiquitinates, and targets for destruction, the RPN4 transcription factor, which upregulates the proteasome genes. The binding of MUB1 may position the RPN4 ubiquitylation site proximal to the Ubiquitin-RAD6 thioester and allow the transfer of Ubiquitin from RAD6 to RPN4. One of its components, MUB1, is a short-lived protein ubiquitinated by the UBR2-RAD6 ubiquitin conjugating enzyme.
MUB1-RAD6-UBR2 ubiquitin ligase complex
Binding to a type-I dockerin domain of a protein. Type-I dockerin domain is the binding partner of type-1 cohesin domain.
type-I dockerin domain binding
Binding to a type-II dockerin domain of a protein. Type-II dockerin domain is the binding partner of type-II cohesin domain.
type-II dockerin domain binding
Binding to a type-III dockerin domain of a protein. Type-III dockerin domain is the binding partner of type-III cohesin domain.
type-III dockerin domain binding
Binding to a type-I cohesin domain of a protein. Type-I cohesin domain is the binding partner of type-I dockerin domain.
type-I cohesin domain binding
Binding to a type-II cohesin domain of a protein. Type-II cohesin domain is the binding partner of type-II dockerin domain.
type-II cohesin domain binding
Binding to a type-III cohesin domain of a protein. Type-III cohesin domain is the binding partner of type-III dockerin domain.
type-III cohesin domain binding
A protein complex that consists of a phospho relay component and a MAPK cascade component. The complex is involved in signaling oxidative stress and osmostress.
Mcs4 RR-MAPKKK complex
A collagen homotrimer of alpha1(XIX) chains; type XIX collagen triple helices localize to basement membrane zones in differentiating muscle cells.
collagen type XIX trimer
A collagen homotrimer of alpha1(XX) chains.
collagen type XX trimer
A collagen homotrimer of alpha1(XXI) chains; type XXI collagen triple helices found in the extracellular matrix component of blood vessel walls and in the cytoplasm of cultured human aortic smooth muscle.
collagen type XXI trimer
A collagen homotrimer of alpha1(XXII) chains; type XXII collagen triple helices acts as a cell adhesion ligand for skin epithelial cells and fibroblasts.
collagen type XXII trimer
A collagen homotrimer of alpha1(XXIII) chains; type XXIII collagen triple helices span the plasma membrane.
collagen type XXIII trimer
A collagen homotrimer of alpha1(XXIV) chains; type XXIV collagen triple helices may participate in regulating type I collagen fibrillogenesis at specific anatomical locations during fetal development.
collagen type XXIV trimer
A collagen homotrimer of alpha1(XXVI) chains.
collagen type XXVI trimer
A collagen homotrimer of alpha1(XXVII) chains. These trimers form thin, non-striated fibrils. Type XXVII collagen triple helices play a role during the calcification of cartilage and the transition of cartilage to bone.
collagen type XXVII trimer
A collagen homotrimer of alpha1(XXVIII) chains.
collagen type XXVIII trimer
A collagen homotrimer of alpha1(XXV) chains; type XXV collagen triple helices span the plasma membrane.
collagen type XXV trimer
A heterotetrameric protein complex involved in the sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm5s2U) at tRNA wobble positions. In E. coli it consists of a central IscS dimer with the two TusA protomers bound to one of the IscS units each via persulfide (-SSH) groups.
IscS-TusA complex
A heterotetrameric protein complex involved in the sulfur transfer during iron-sulfur cluster assembly and in the modification of tRNA wobble positions. In E. coli it consists of a central IscS dimer with the IscU protomers attached to one of the IscS units each via a disulfide (-SSH) group.
IscS-IscU complex
A tetrameric protein complex capable of acetyltransferase activity. It can catalyze the transfer of an acetyl group from acetyl-CoA to an acceptor residue on histone H-3, histone H-4, or on polyamines. The complex is also capable of acetylating certain small basic proteins. The two Hpa2 dimers that make up the tetramer are held together by interactions between the bound acetyl-CoA molecules.
Hpa2 acetyltransferase complex
A protein complex that acts as a two-component GTPase-activating protein for Tem1 GTPase, thus regulating a signal transduction cascade, called the mitotic exit network (MEN), which is required for mitotic exit and cytokinesis. Bub2/Bfa1 keeps Tem1 inactive until the spindle is properly oriented, thus inhibiting MEN activation.
Bfa1-Bub2 complex
A homotrimeric or homopentameric glycoprotein that functions at the interface of the cell membrane and the extracellular matrix through its interactions with proteins and proteoglycans, such as collagens, integrins and fibronectin, to regulate matrix structure and cellular behaviour.
thrombospondin complex
A region of facultative heterochromatin formed dynamically at specific loci in response to environmental signals, independently of RNAi.
heterochromatin island
A heterodimeric protein complex consisting of BID and BCL-xl, members of the Bcl-2 family of anti- and proapoptotic regulators.
BID-BCL-xl complex
The movement of substances between cells via gap junctions. A gap junction is a fine cytoplasmic channel, found in animal cells, that connects the cytoplasm of one cell to that of an adjacent cell, allowing ions and other molecules to pass freely between the two cells.
gap junction-mediated intercellular transport
A protein complex facilitating glucose transport into, out of or within a cell, or between cells.
glucose transporter complex
A ubiquitin ligase complex. In D. melanogaster, it regulates ubiquitination and proteolysis of the BMP receptor Thickveins in cystoblasts, potentially by controlling Tkv ubiquitination and degradation.
Fused-Smurf ubiquitin ligase complex
An actin-rich cytoskeletal network located beneath the microvilli of the apical plasma membrane of polarized epithelial cells. In addition to actin filaments, the terminal web may contain actin-binding proteins, myosin motor proteins, and intermediate filaments. The terminal web can function as a contractile structure that influences the spatial distribution of microvilli as well as the development and morphogenesis of tissues containing polarized epithelial cells.
terminal web
An extracellular matrix consisting of a densely packed organomineral assembly in which the mineral phase represents the majority of the material by weight.
organomineral extracellular matrix
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of biotin.
cellular response to biotin starvation
The developmental process in which the hyaloid vascular plexus is destroyed as a part of its normal progression.
hyaloid vascular plexus regression
The area in the center of the meiotic spindle where the spindle microtubules from opposite poles overlap.
meiotic spindle midzone
Advancement of the mitotic cleavage furrow from the outside of the cell inward towards the center of the cell. The cleavage furrow acts as a 'purse string' which draws tight to separate daughter cells during mitotic cytokinesis and partition the cytoplasm between the two daughter cells. The furrow ingresses until a cytoplasmic bridge is formed.
mitotic cleavage furrow ingression
The chemical reactions and pathways resulting in the formation of a lactosyl-ceramide derivative in which a galactose is linked to the galactose via an alpha 1,3 linkage (vs alpha 1,4 for globosides).
isogloboside biosynthetic process
The directed movement of iron ions into the phloem from the xylem.
xylem-to-phloem iron transport
A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 33 of the ubiquitin monomers, is added to a protein.
protein K33-linked ubiquitination
A trimeric cell-cell fusion complex that serves as a scaffold for zippering up the extracellular domains, bringing the transmembrane segments into close proximity such that they can continue zippering within the two membranes into one. Two prefusion monomers cluster at the surface of adjacent cells. Parallel EFF-1 interactions occur across cells and a third monomer, which can come from either cell, adds on to make an intermediate, extended trimer.
EFF-1 complex
A protein complex, at least composed of CUL7, CCDC8 and OBSL1, that is required for maintaining microtubule and genome integrity.
3M complex
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cell wall damage. The process begins with detection of the damage and ends with a change in state or activity of the cell.
cellular response to cell wall damage
Any process which produces queuosine from derivatives of it, without de novo synthesis.
queuosine salvage
The process occurring during the embryonic phase whose specific outcome is the progression of the lung over time, from its formation to the mature structure.
embryonic lung development
The process occurring during the embryonic phase whose specific outcome is the progression of the liver over time, from its formation to the mature structure.
embryonic liver development
The process occurring during the embryonic phase whose specific outcome is the progression of the brain over time, from its formation to the mature structure.
embryonic brain development
Binding to a protein antigen.
protein antigen binding
Catalysis of the reaction: hercynylcysteine sulfoxide + 2H+ = ergothioneine + pyruvate + ammonium.
hercynylcysteine sulfoxide lyase activity (ergothioneine-forming)
The release of snoRNA from pre-rRNA.
snoRNA release from pre-rRNA
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin-like growth factor stimulus.
response to insulin-like growth factor stimulus
Catalysis of the reaction: glyoxal + H2O = glycolic acid. Catalysis occurs in the absence of a cofactor.
glyoxalase (glycolic acid-forming) activity
Binding to a protein that is part of an extracellular matrix.
extracellular matrix protein binding
The posttranscriptional addition a methyl group to the 2'-oxygen atom of a nucleotide residue in an U6 snRNA molecule.
U6 2'-O-snRNA methylation
Catalysis of the reaction: MAP kinase threonine phosphate + H2O = MAP kinase threonine + phosphate and MAP kinase serine phosphate + H2O = MAP kinase serine + phosphate.
MAP kinase serine/threonine phosphatase activity
The phosphorylation by a protein of one or more of its own threonine amino acid residues, or a threonine residue on an identical protein.
peptidyl-threonine autophosphorylation
Binding to an F-box domain of a protein.
F-box domain binding
Binding to a U1 small nuclear ribonucleoprotein particle.
U1 snRNP binding
Binding to a U2 small nuclear ribonucleoprotein particle.
U2 snRNP binding
A membrane-bounded intracellular vesicle involved in the degradation of peroxisome by macropexophagy.
pexophagosome
Binding to a transferrin receptor.
transferrin receptor binding
Binding to a leptin receptor.
leptin receptor binding
Any process that reduces or removes the toxicity of iron ion. These include transport of iron away from sensitive areas and to compartments or complexes whose purpose is sequestration of iron ion.
detoxification of iron ion
A NuA3 complex that catalyzes the acetylation of Histone H3. In S. cerevisiae, this complex consists of Eaf6p, Nto1p, Sas3p, Taf14p, Yng1p and associates with H3K4me3 using Yng1p.
NuA3a histone acetyltransferase complex
A NuA3 complex that catalyzes the acetylation of Histone H3. In S. cerevisiae, this complex consists of Eaf6p, Nto1p, Sas3p, Taf14p, Pdp3 and associates with H3K4me3 via Pdp3p.
NuA3b histone acetyltransferase complex
Binding to uni-strand piRNA clusters, double-stranded DNA regions that give rise to PIWI-interacting RNAs (piRNAs) that map predominantly to only one strand and exhibit hallmarks of canonical Pol II transcription. Uni-strand piRNA clusters are found in many taxa.
piRNA uni-strand cluster binding
Binding to dual-strand piRNA clusters, double-stranded DNA regions that give rise to PIWI-interacting RNAs (piRNAs) where piRNAs originate from both DNA strands via noncanonical transcription.
piRNA dual-strand cluster binding
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultrasonic stimulus.
response to ultrasound
Nuclear transcriptional repressor complex that is capable of negatively regulating CLOCK-BMAL-dependent transactivation of genes in a delayed negative feedback manner which generates circadian rhythms.
Cry-Per complex
An RNA interference where the silencing signal spreads 5' along the target mRNA, outside of the initial target sequence. Typically involves the formation of secondary siRNAs formed when the initial mRNA target sequence functions as a template for 5' to 3' synthesis of new dsRNA.
5' transitive RNA interference
An RNA interference where the silencing signal spreads 3' along the target mRNA, outside of the initial target sequence. Typically involves the formation of secondary siRNAs formed when the initial mRNA target sequence functions as a template for 5' to 3' synthesis of new dsRNA.
3' transitive RNA interference
The pathway by which a ribonucleotide is removed from DNA and replaced by a deoxyribonucleotide. The ribonucleotide is incised by RNase H2, and further excised by an endonuclease. The resulting 1 nt gap is then repaired by DNA polymerase and DNA ligase.
ribonucleotide excision repair
Catalysis of the reaction: ATP + H2O = ADP + phosphate, in the presence of single-stranded DNA; drives the unwinding of the DNA helix in the direction 3' to 5'.
single-stranded 3'-5' DNA helicase activity
The process in which the nematode tail spike is generated and organized. An example of this process is seen in C. elegans, where the tapered tail spike is formed during embryogenesis by a filamentous process that passes posteriorly through hyp10, the tail ventral hypodermis; the filamentous process is formed by a binucleate cell, the tail-spike cell, that subsequently undergoes programmed cell death.
tail spike morphogenesis
The regrowth of bone following its loss or destruction.
bone regeneration
A multiprotein complex that is involved in the transcription regulation of mating genes in the yeast S. cerevisiae.
Ste12p-Dig1p-Dig2p complex
A multiprotein complex that is involved in the transcriptional regulation of primarily filamentation genes, but also mating genes, in the yeast S. cerevisiae.
Tec1p-Ste12p-Dig1p complex
A protein complex that is involved in endocytosis in the yeast S. cerevisiae.
Rvs161p-Rvs167p complex
A protein complex that functions as a phospholipid-translocating P-Type ATPase. In budding yeast, this complex consists of Cdc50p and Drs2p proteins, and is involved in the trafficking of transport vesicles between the late Golgi and the early endosome.
Cdc50p-Drs2p complex
Catalysis of the reaction: S-methyl-5'-thioadenosine + thermospermine + H+ = S-adenosyl 3-(methylthio)propylamine + spermidine.
thermospermine oxidase activity
The directed movement of phosphoenolpyruvate into the Golgi lumen across the Golgi membrane.
phosphoenolpyruvate transmembrane import into Golgi lumen
Any of the mitotic spindle microtubules that come from each pole and overlap at the spindle midzone.
mitotic spindle polar microtubule
Catalysis of the reaction: acetyl-CoA + a xylan= CoA + an acetylated xylan.
xylan O-acetyltransferase activity