NothingMuch/GO-Terms huggingface dataset:
The regrowth of muscle tissue to repair injured or damaged muscle fibers in the postnatal stage at the neuromuscular junction. Regeneration of neuromuscular junctions occurs in an orderly way and relies on communication between nerve and muscle. Skeletal myofibers regenerate after injury and form neuro-muscular junctions with motor axons similar to normal ones. Regenerating myofibers develop within the basal lamina sheaths (satellite cells) of original myofibers.
skeletal muscle regeneration at neuromuscular junction
A process, occurring in skeletal muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse.
skeletal muscle atrophy
Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle atrophy.
negative regulation of muscle atrophy
Any process that activates or increases the frequency, rate or extent of muscle atrophy.
positive regulation of muscle atrophy
Any process that activates or increases the frequency, rate or extent of muscle hyperplasia.
positive regulation of muscle hyperplasia
Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle hyperplasia.
negative regulation of muscle hyperplasia
Any process that activates or increases the frequency, rate or extent of tonic skeletal muscle contraction.
positive regulation of tonic skeletal muscle contraction
Any process that stops, prevents, or reduces the frequency, rate or extent of tonic skeletal muscle contraction.
negative regulation of tonic skeletal muscle contraction
The region between the inner and outer lipid bilayers of the longitudinal sarcoplasmic reticulum envelope. The longitudinal sarcoplasmic reticulum lumen is continuous with the lumen contained within the terminal cisternae.
longitudinal sarcoplasmic reticulum lumen
The region between the inner and outer lipid bilayers of the terminal cisterna envelope. This space is enriched in calsequestrin.
terminal cisterna lumen
A process, occurring in smooth muscle, in which there is an increase in cell number by cell division, often leading to an increase in the size of an organ.
smooth muscle hyperplasia
Any process that modulates the frequency, rate or extent of somitogenesis.
regulation of somitogenesis
Any process that activates, maintains or increases the frequency, rate or extent of skeletal muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction.
positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion
Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction.
negative regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion
The regrowth of axons following their loss or damage at the neuromuscular junction. Motor axons regenerate after injury and they form neuro-muscular junctions with skeletal myofibers similar to normal ones.
axon regeneration at neuromuscular junction
The process in which a cell becomes capable of differentiating autonomously into a skeletal muscle satellite cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.
skeletal muscle satellite cell fate specification
The process in which a cell becomes capable of differentiating autonomously into a skeletal muscle satellite cell regardless of its environment; upon determination, the cell fate cannot be reversed.
skeletal muscle satellite cell fate determination
A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the arteriole. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The arteriole is the smallest division of the artery located between the muscular arteries and the capillaries.
arteriole smooth muscle contraction
The process in which a satellite cell becomes capable of differentiating autonomously into a myoblast regardless of its environment; upon determination, the cell fate cannot be reversed. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
myoblast fate determination involved in skeletal muscle regeneration
The process in which a satellite cell becomes capable of differentiating autonomously into a myoblast in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
myoblast fate specification involved in skeletal muscle regeneration
Any process that modulates the frequency, rate or extent of satellite cell proliferation; dependent on specific growth factor activity such as fibroblast growth factors and transforming growth factor beta.
growth factor dependent regulation of skeletal muscle satellite cell proliferation
The multiplication or reproduction of myoblasts, resulting in the expansion of the cell population. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
myoblast proliferation involved in skeletal muscle regeneration
A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the body of stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The body of stomach is the part of the stomach that lies between the fundus above and the pyloric antrum below; its boundaries are poorly defined.
stomach body smooth muscle contraction
A process in which cross bridges are broken and reformed during filament sliding as part of the regulation of the velocity of shortening in skeletal muscle contraction.
cross bridge cycling involved in regulation of the velocity of shortening in skeletal muscle contraction
The process in which actin and myosin interact, split ATP and generate force during skeletal muscle contraction. This process is one of the components of the regulation of the force of skeletal muscle contraction.
cross bridge formation involved in regulation of the velocity of shortening in skeletal muscle contraction
The process resulting in the physical partitioning and separation of a myoblast into daughter cells. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
myoblast division
The series of events by which an electrical stimulus is received and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation.
detection of electrical stimulus involved in regulation of muscle adaptation
The series of events in which a muscle inactivity stimulus is received by a cell and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation.
detection of muscle inactivity involved in regulation of muscle adaptation
A process, occurring in smooth muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse.
smooth muscle atrophy
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rest stimulus. This process occurs as part of the regulation of muscle adaptation.
response to rest involved in regulation of muscle adaptation
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a denervation stimulus. This process occurs as part of the regulation of muscle adaptation.
response to denervation involved in regulation of muscle adaptation
A process, occurring in the heart, in which a decrease in cell mass and then in heart size occurs due to shrinking of the individual cells. The shrinkage is caused by protein degradation.
cardiac muscle atrophy
A process in which non-proliferating myoblasts, after migrating to the site of injury, fuse into existing damaged fibers or fuse to myotubes to form new fibers, as part of the process of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
myoblast fusion involved in skeletal muscle regeneration
The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. This occurs as part of the process of skeletal muscle regeneration. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.
myotube cell development involved in skeletal muscle regeneration
A developmental process, independent of morphogenetic (shape) change, that is required for a myoblast cell to attain its fully functional state involved in muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
myoblast maturation involved in muscle regeneration
Any process that modulates the velocity of muscle filament sliding, and consequently contributes to the regulation of the velocity of shortening of skeletal muscle contraction.
regulation of muscle filament sliding speed involved in regulation of the velocity of shortening in skeletal muscle contraction
Catalysis of the reaction: reduced rubredoxin + NADP+ = oxidized rubredoxin + NADPH + H+.
rubredoxin-NADP+ reductase activity
Catalysis of the transfer of electrons between pyridine nucleotides (obligatory two-electron carriers) and hemes or (2Fe-2S) centers (obligatory one-electron carriers) in respiration, photosynthesis, and many oxygenase systems.
phthalate dioxygenase reductase activity
A protein complex that possesses methane monooxygenase activity; dimeric and trimeric complexes have been characterized.
methane monooxygenase complex
Combining with secretin to initiate a change in cell activity.
secretin receptor activity
Combining with the corticotrophin-releasing factor family of ligands, including the urocortins, to initiate a change in cell activity.
corticotrophin-releasing factor receptor activity
Binds to and stops, prevents or reduces the activity of alpha-amylase.
alpha-amylase inhibitor activity
The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome.
DNA integration
Enables the transfer of mercury (Hg2+) ions from one side of a membrane to the other.
mercury ion transmembrane transporter activity
Enables the transfer of vanadium (V) ions from one side of a membrane to the other.
vanadium ion transmembrane transporter activity
Enables the transfer of chlorate, ClO3-, from one side of a membrane to the other.
chlorate transmembrane transporter activity
Enables the transfer of chromate from one side of a membrane to the other. Chromate is the anion of chromic acid, H2CrO4 (aq) or CrO3.
chromate transmembrane transporter activity
Enables the transfer of silicates from one side of a membrane to the other. Silicates are the salts of silicic acids, and are usually composed of silicon and oxygen (SiO), one or more metals, and possibly hydrogen. Types of silicate include unisilicates, metasilicates and hydrous silicates.
silicate transmembrane transporter activity
Enables the transfer of phosphoglycerates from one side of a membrane to the other. Phosphoglycerates are important intermediates in glycolysis and 3-phosphoglycerate is a precursor in serine biosynthesis.
phosphoglycerate transmembrane transporter activity
Enables the transfer of allantoate from one side of a membrane to the other. Allantoate is the end product of purine metabolism in mammals and some fish, formed form allantoin. It is widely distributed in plants as an important source of stored nitrogen.
allantoate transmembrane transporter activity
The directed movement of bile acid and bile salts out of a hepatocyte and into the bile canaliculus by means of an agent such as a transporter or pore. Bile canaliculi are the thin tubes formed by hepatocyte membranes. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine.
canalicular bile acid transmembrane transporter activity
Enables the transfer of bilirubin from one side of a membrane to the other. Bilirubin is a linear tetrapyrrole produced in the reticuloendothelial system from biliverdin and transported to the liver as a complex with serum albumin. In the liver, bilirubin is converted to bilirubin bisglucuronide, which is excreted in the bile.
bilirubin transmembrane transporter activity
Enables the transfer of oxaloacetate, the anion of oxobutanedioic acid, from one side of a membrane to the other.
oxaloacetate transmembrane transporter activity
Enables the transfer of adenine, 6-aminopurine, from one side of a membrane to the other.
adenine transmembrane transporter activity
Enables the transfer of cytidine, cytosine riboside, from one side of a membrane to the other.
cytidine transmembrane transporter activity
Enables the transfer of a pyrimidine nucleotide, any compound consisting of a pyrimidine nucleoside esterified with (ortho)phosphate, from one side of a membrane to the other.
pyrimidine nucleotide transmembrane transporter activity
Enables the energy-independent facilitated diffusion of glycerol through a transmembrane aqueous pore or channel.
glycerol channel activity
Enables the energy-independent facilitated diffusion of propanediol through a transmembrane aqueous pore or channel.
propanediol channel activity
Enables the energy-independent facilitated diffusion of methylammonium through a transmembrane aqueous pore or channel. Methylammonium is CH3NH2.
methylammonium channel activity
Enables the energy-independent facilitated diffusion of urea through a transmembrane aqueous pore or channel.
urea channel activity
Enables the transmembrane transfer of a potassium ion by an inwardly-rectifying voltage-gated channel, where the inward rectification is due to a voltage-dependent block of the channel pore by ATP. An inwardly rectifying current-voltage relation is one where at any given driving force the inward flow of K+ ions exceeds the outward flow for the opposite driving force.
ATP-activated inward rectifier potassium channel activity
An ionotropic glutamate receptor activity that exhibits fast gating by glutamate, acts by opening a cation channel permeable to sodium and potassium, and for which kainate is an agonist.
kainate selective glutamate receptor activity
A ligand-gated ion channel activity which transports calcium in response to emptying of intracellular calcium stores.
store-operated calcium channel activity
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: fructose(out) = fructose(in).
fructose uniporter activity
Catalysis of the reaction: acetyl-CoA(out) + CoA(in) = acetyl-CoA(in) + CoA(out).
acetyl-CoA:CoA antiporter activity
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cystine(out) + glutamate(in) = cystine(in) + glutamate(out).
cystine:glutamate antiporter activity
Enables the transfer of organic anions from one side of a membrane to the other, in a sodium independent manner.
sodium-independent organic anion transmembrane transporter activity
Enables the transfer of thyroid hormones from one side of a membrane to the other. Thyroid hormone are any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine.
thyroid hormone transmembrane transporter activity
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: galactose(out) + Na+(out) = glucose(in) + Na+(in).
galactose:sodium symporter activity
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycine(out) + Na+(out) = glycine(in) + Na+(in).
glycine:sodium symporter activity
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: purine(out) + Na+(out) = nucleoside(in) + Na+(in).
purine-specific nucleoside:sodium symporter activity
Enables the energy independent passage of nucleoside, sized less than 1000 Da, across a membrane. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria.
nucleoside-specific channel forming porin activity
A porin that acts in the assembly of fimbria together with fimbrial chaperone.
fimbrial usher porin activity
Transports a passenger protein from the periplasm to the external milieu; the passenger protein and the porin are the N- and C-terminal regions of the same protein, respectively.
autotransporter activity
Enables the transfer of a long-chain fatty acid from one side of a membrane to the other. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons. This transporter is a porin and so enables the energy independent passage of substances, sized less than 1000 Da, across a membrane. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria.
long-chain fatty acid transporting porin activity
Binding to cholesterol (cholest-5-en-3-beta-ol); the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
cholesterol binding
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: pantothenate(out) + Na+(out) = pantothenate(in) + Na+(in).
pantothenate:sodium symporter activity
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(in) + H+(out) = K+(out) + H+(in), where glutathione maintains the closed state.
glutathione-regulated potassium exporter activity
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: citrate(out) + succinate(in) = citrate(in) + succinate(out).
citrate:succinate antiporter activity
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: tartrate(out) + succinate(in) = tartrate(in) + succinate(out).
tartrate:succinate antiporter activity
Enables the transfer of galacturonate from one side of a membrane to the other. Galacturonate is the uronic acid formally derived from galactose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group.
galacturonate transmembrane transporter activity
Enables the transfer of alkanes from one side of a membrane to the other. Alkanes are saturated aliphatic hydrocarbon compounds.
alkane transmembrane transporter activity
Enables the transfer of spermidine, N-(3-aminopropyl)-1,4-diaminobutane, from one side of a membrane to the other.
spermidine transmembrane transporter activity
Enables the transfer of ferric-enterobactin from one side of a membrane to the other.
ferric-enterobactin transmembrane transporter activity
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: branched-chain amino acid(out) + cation(out) = branched-chain amino acid(in) + cation(in).
branched-chain amino acid:sodium symporter activity
The directed movement of oxygen (O2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
oxygen transport
The directed movement of vanadium (V) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
vanadium ion transport
The directed movement of lead (Pb) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
lead ion transport
The directed movement of chlorate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
chlorate transport
The directed movement of chromate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
chromate transport
The directed movement of cyanate, NCO-, the anion of cyanic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
cyanate transport
The directed movement of nitrite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
nitrite transport
The directed movement of tellurite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
tellurite transport
Enables the transfer of bile acid from one side of a hepatocyte plasma membrane into a bile canaliculus. Bile canaliculi are the thin tubes formed by hepatocyte membranes. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine.
canalicular bile acid transport
The directed movement of bilirubin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
bilirubin transport
The directed movement of mevalonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
mevalonate transport
The directed movement of sialic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
sialic acid transport
The directed movement of fumarate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
fumarate transport
The directed movement of glucose-6-phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glucose-6-phosphate is a monophosphorylated derivative of glucose with the phosphate group attached to C-6.
glucose-6-phosphate transport
The directed movement of N-acetylgalactosamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. N-acetylgalactosamine, 2-acetamido-2-deoxygalactopyranose, is the n-acetyl derivative of galactosamine.
N-acetylgalactosamine transport
The directed movement of N-acetylglucosamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
N-acetylglucosamine transport