NothingMuch/GO-Terms huggingface dataset:
The directed movement of methylgalactoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Methylgalactoside is a compound in which the H of the OH group on carbon-1 of galactose is replaced by a methyl group.
methylgalactoside transport
The directed movement of lactose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lactose is a disaccharide 4-O-beta-D-galactopyranosyl-D-glucose, and constitutes roughly 5% of the milk in almost all mammals.
lactose transport
The directed movement of melibiose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Melibiose is the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose.
melibiose transport
The directed movement of raffinose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Raffinose occurs in plants almost as commonly as sucrose and is present in cereal grains, cotton seeds, and many legumes. It is synthesized from sucrose by transfer of a galactopyranoside from myo-inositol.
raffinose transport
The directed movement of beta-glucans into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Beta-glucans are compounds composed of glucose residues linked by beta-glucosidic bonds.
beta-glucan transport
The directed movement of teichoic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Teichoic acid is any polymer occurring in the cell wall, membrane or capsule of Gram-positive bacteria and containing chains of glycerol phosphate or ribitol phosphate residues.
teichoic acid transport
The directed movement of propanediol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Propanediol is a sweet colorless, viscous, hygroscopic liquid used as an antifreeze and in brake fluid; it is also as a humectant in cosmetics and personal care items, although it can be absorbed through the skin with harmful effects.
propanediol transport
The directed movement of S-methylmethionine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
S-methylmethionine transport
The directed movement of diaminopimelate, the anion of 2,6-diaminoheptanedioic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
diaminopimelate transport
The directed movement of cadaverine, 1,5-pentanediamine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
cadaverine transport
The directed movement of amines into, out of or within chromaffin granules.
chromaffin granule amine transport
The active transport of aminergic neurotransmitters into a synaptic vesicle. This import is fuelled by an electrochemical gradient across the vesicle membrane, established by the action proton pumps.
aminergic neurotransmitter loading into synaptic vesicle
The directed movement of putrescine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Putrescine is 1,4-diaminobutane, the polyamine formed by decarboxylation of ornithine and the metabolic precursor of spermidine and spermine.
putrescine transport
The directed movement of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleotide), within a cell.
intracellular nucleoside transport
The directed movement of cytidine, cytosine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
cytidine transport
The directed movement of uridine, uracil riboside, across a lipid bilayer, by means of some agent such as a transporter or pore.
uridine transmembrane transport
The directed movement of xanthosine, xanthine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
xanthosine transport
The directed movement of choline into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Choline (2-hydroxyethyltrimethylammonium) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.
choline transport
The directed movement of biopterin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Biopterin is a growth factor for certain protozoans and some insects; it is widely distributed in tissues and functions in a reduced form, tetrahydrobiopterin, as a hydroxylation coenzyme.
biopterin transport
The directed movement of 5-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate, into, out of, within, or between cells, by means of some agent such as a transporter or pore.
5-formyltetrahydrofolate transport
The directed movement of alkanes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Alkanes are saturated aliphatic hydrocarbon compounds.
alkane transport
The directed movement of aminotriazole into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Aminotriazole is an effective weed killer that also possesses some antithyroid activity.
aminotriazole transport
The directed movement of cycloheximide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Cycloheximide is an antibiotic produced by Streptomyces which interferes with protein synthesis in eukaryotes.
cycloheximide transport
The directed movement of fluconazole into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fluconazole is an antifungal drug used for oral candidiasis and cryptococcal meningitis; it is still under study for treatment of vaginal candidiasis and other fungal infections.
fluconazole transport
The chemical reactions and pathways resulting in the conversion of methanol to methyl-Coenzyme M.
methanol oxidation
The chemical reactions and pathways by which a purine ribonucleotide is synthesized from another purine ribonucleotide.
purine ribonucleotide interconversion
The chemical reactions and pathways by which a purine deoxyribonucleotide is synthesized from another purine deoxyribonucleotide.
purine deoxyribonucleotide interconversion
The chemical reactions and pathways by which a pyrimidine ribonucleotide is synthesized from another pyrimidine ribonucleotide.
pyrimidine ribonucleotide interconversion
The chemical reactions and pathways by which a pyrimidine deoxyribonucleotide is synthesized from another pyrimidine deoxyribonucleotide.
pyrimidine deoxyribonucleotide interconversion
A specific global change in the metabolism of a bacterial cell (the downregulation of nucleic acid and protein synthesis, and the simultaneous upregulation of protein degradation and amino acid synthesis) as a result of starvation.
stringent response
The transport of protons across a membrane to generate an electrochemical gradient (proton-motive force) that powers GTP synthesis.
GTP synthesis coupled proton transport
The transport of protons against an electrochemical gradient, using energy from electron transport.
electron transport coupled proton transport
Binds to and increases the activity of the enzyme phospholipase A2.
phospholipase A2 activator activity
A product of the fusion of the mitochondria during spermatogenesis. After the completion of meiosis the mitochondria of the spermatid collect along side the nucleus and fuse into two masses; these wrap around each other to produce the spherical Nebenkern. During flagellum elongation the Nebenkern unfolds and the two derivatives (major and minor mitochondrial derivatives) elongate down the axoneme.
Nebenkern
The larger of the two mitochondrial derivatives that arise by the unfolding of the Nebenkern during flagellum elongation; the major mitochondrial derivative is ovoid and darker than the minor derivative.
major mitochondrial derivative
The smaller of the two mitochondrial derivatives that arise by the unfolding of the Nebenkern during flagellum elongation.
minor mitochondrial derivative
A protein complex comprising alpha- and beta-dystrobrevin; forms part of the dystrophin glycoprotein complex.
dystrobrevin complex
Acts as a trigger for a pattern specification process when present at a specific concentration within a gradient.
morphogen activity
A heterodimeric DNA polymerase complex that catalyzes error-prone DNA synthesis in contexts such as translesion synthesis and double-stranded break repair. First characterized in Saccharomyces, in which the subunits are Rev3p and Rev7p; a third protein, Rev1p, is often associated with the polymerase dimer.
zeta DNA polymerase complex
The reception of a (visible light) photon by a cell, visible light being defined as having a wavelength within the range 380-780 nm.
absorption of visible light
The reception of a (UV light) photon by a cell, UV light being defined as having a wavelength within the range 13.6-400 nm.
absorption of UV light
Any process that modulates the frequency, rate or extent of light-activated channel activity.
regulation of light-activated channel activity
The process in which synaptic vesicles are directed to specific destination membranes, mediated by molecules at the vesicle membrane and target membrane surfaces.
synaptic vesicle targeting
The action characteristic of myostimulatory hormone, a peptide hormone that stimulates muscle contraction.
myostimulatory hormone activity
The action characteristic of myostimulatory hormone, a peptide hormone that inhibits muscle contraction.
myoinhibitory hormone activity
The action characteristic of ecdysiostatic hormone, a peptide hormone that inhibits ecdysone secretion.
ecdysiostatic hormone activity
A translation release factor that is specific for one or more particular termination codons; acts at the ribosomal A-site and require polypeptidyl-tRNA at the P-site.
translation release factor activity, codon specific
A translation release factor that is not specific to particular codons; binds to guanine nucleotides.
translation release factor activity, codon nonspecific
Catalysis of the dehydrogenation of phytoene to produce a carotenoid intermediate such as phytofluene.
phytoene dehydrogenase activity
Binding to bacteriochlorophyll c, a chlorophyll of photosynthetic bacteria, for example green sulfur bacteria.
bacteriochlorophyll c binding
The formation of clathrin coated pits in the presynaptic membrane endocytic zone, triggered by the presence of high concentrations of synaptic vesicle components. This process leads to, but does not include budding of the membrane to form new vesicles.
synaptic vesicle coating
The process in which a neuronal cell in a multicellular organism recognizes chemoattractant signals from, and grows towards, potential targets.
synaptic target attraction
The process in which a neuronal cell in a multicellular organism recognizes chemorepellent signals that inhibit its growth toward the source.
synaptic target inhibition
The process that mediates the transfer of information from the cells of a muscle to those of its intended target, thereby identifying the target site.
determination of muscle attachment site
Catalysis of the reaction: selenocysteine + S-adenosyl-L-methionine = Se-methylselenocysteine + S-adenosyl-homocysteine.
selenocysteine methyltransferase activity
Binding to AMP, adenosine monophosphate.
AMP binding
Catalysis of the reaction: deethylsimazine + H2O = N-ethylammeline + chloride + H+.
N-ethylammeline chlorohydrolase activity
Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in N-acetyl-beta-D-glucosaminides.
beta-N-acetylglucosaminidase activity
An inclusion body formed by dynein-dependent retrograde transport of an aggregated protein on microtubules.
aggresome
A transamidation reaction that results in the cleavage of the polypeptide chain and the concomitant transfer of the GPI anchor to the newly formed carboxy-terminal amino acid of the anchored protein. The cleaved C-terminal contains the C-terminal GPI signal sequence of the newly synthesized polypeptide chain.
attachment of GPI anchor to protein
The modification of high-mannose N-glycans by UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase and the subsequent removal of the N-acetylglucosamine residues yielding mannose-6-P that occurs in the ER-Golgi apparatus to N-glycans destined for the lysosome.
N-glycan processing to lysosome
The modification of high-mannose (Man9-Asn) N-glycans by mannosyl-oligosaccharide 1,2-alpha-mannosidase. This may result in Man8GlcNAc2-Asn N-glycans (which in yeast may be subsequently modified by the addition of further mannose residues) or Man5GlcNAc2-Asn N-glycans that are substrates for further diversification in the Golgi apparatus.
N-glycan processing to secreted and cell-surface N-glycans
The generation, in the Golgi apparatus, of side chain diversity from high mannose Man5GlcNAc2-Asn N-glycans by specific glycosyltransferases and glycosidases.
N-glycan diversification
The process in which photoreceptors are arranged in ommatidia in the dorsal and ventral fields to be mirror images. The polarity is established in the imaginal discs concurrently with cell fate specification.
ommatidial rotation
The process whose specific outcome is the progression of the mushroom body over time, from its formation to the mature structure. The mushroom body is composed of the prominent neuropil structures of the insect central brain, thought to be crucial for olfactory associated learning. These consist mainly of a bulbous calyx and tightly packaged arrays of thin parallel fibers of the Kenyon cells.
mushroom body development
The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
basolateral plasma membrane
The portion of the plasma membrane at the lateral side of the cell. In epithelial cells, lateral plasma membranes are on the sides of cells which lie at the interface of adjacent cells.
lateral plasma membrane
The binding of a cell to the extracellular matrix via adhesion molecules that require the presence of calcium for the interaction.
calcium-dependent cell-matrix adhesion
Complex of peripheral cytoplasmic proteins (alpha-, beta- and gamma-catenin) that interact with the cytoplasmic region of uvomorulin/E-cadherin to connect it to the actin cytoskeleton.
catenin complex
The process in which the anatomical structures of an imaginal disc-derived leg joint are generated and organized. The leg joint is a flexible region that separates the rigid sections of a leg to allow movement in a controlled manner. An example of this is found in Drosophila melanogaster.
imaginal disc-derived leg joint morphogenesis
Catalysis of the reaction: palmitoyl-CoA + O2 = trans-2,3-dehydropalmitoyl-CoA + hydrogen peroxide.
palmitoyl-CoA oxidase activity
Catalysis of the reaction: pristanoyl-CoA + O2 = trans-2,3-dehydropristanoyl-CoA + hydrogen peroxide.
pristanoyl-CoA oxidase activity
Increases the activity of the enzyme tryptophase hydroxylase.
tryptophan hydroxylase activator activity
Combining with a C-X3-C chemokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. A C-X3-C chemokine has three amino acids between the first two cysteines of the characteristic four-cysteine motif.
C-X3-C chemokine receptor activity
Combining with substance P, the peptide Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met, to initiate a change in cell activity.
substance P receptor activity
Combining with orexin to initiate a change in cell activity.
orexin receptor activity
Combining with growth hormone-releasing hormone to initiate a change in cell activity.
growth hormone-releasing hormone receptor activity
A copper chaperone activity that specifically delivers copper to the Cu-Zn superoxide dismutase, to activate superoxide dismutase activity.
superoxide dismutase copper chaperone activity
Processing which a protein carries out itself. This involves actions such as the autolytic removal of residues to generate the mature form of the protein.
protein autoprocessing
The conversion of a cytosine residue to uridine in an RNA molecule by deamination.
cytidine to uridine editing
The conversion of a uridine residue to cytosine in an RNA molecule by amination.
uridine to cytidine editing
The process in which a peroxisome membrane is synthesized, aggregates, and bonds together.
peroxisome membrane biogenesis
A protein complex that contains flotillin-1 and flotillin-2, and may contain associated proteins. Flotillins associate into membrane microdomains resembling caveolae.
flotillin complex
An enzyme complex containing an iron-iron cluster found in species such as the photosynthetic bacterium Rhodobacter capsulatus. It is composed of two main subunits, dinitrogenase and nitrogenase reductase. Dinitrogenase, the iron-iron containing subunit, has an alpha1-beta2 or alpha2-beta2 structure, and the nitrogenase reductase subunit is a homodimer. Functions in the catalysis of the formation of oxidized ferredoxin and ammonia from reduced ferredoxin and nitrogen.
iron-iron nitrogenase complex
Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end to yield 3' phosphomonoesters.
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters
Catalysis of the hydrolysis of a single C-terminal amino acid residue from a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
cysteine-type carboxypeptidase activity
Catalysis of the release of the N-terminal pyroglutamyl group from a peptide or protein.
pyroglutamyl-peptidase activity
A protein complex that forms a transmembrane channel through which chloride ions may pass in response to glycine binding to the channel complex or one of its constituent parts.
glycine-gated chloride channel complex
Binding to a glycoside in which the sugar group is galactose.
galactoside binding
A complex of two kinesin heavy chains and two kinesin light chains.
kinesin I complex
A complex consisting of two distinct motor subunits that form a heterodimer complexed with a third non-motor accessory subunit, the kinesin associated protein or KAP; the KIF3 heterodimer interacts via its C-terminal portion with KAP, which is thought to regulate the binding of the motor to cargo membranes.
kinesin II complex
Combining with a natriuretic peptide and transmitting the signal to initiate a change in cell activity.
natriuretic peptide receptor activity
Combining with alpha-2 macroglobulin and delivering alpha-2 macroglobulin into the cell via receptor-mediated endocytosis.
alpha-2 macroglobulin receptor activity
Catalysis of the hydrolysis of 3'-phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between DNA topoisomerase I and DNA.
3'-tyrosyl-DNA phosphodiesterase activity
The linkage of the chromophore phycobiliviolin to phycoerythrocyanin.
protein-phycobiliviolin linkage
The linkage of the chromophore phycocyanobilin to phycocyanin or allophycocyanin.
protein-phycocyanobilin linkage
The linkage of the chromophore phycourobilin to phycoerythrins.
protein-phycourobilin linkage
The linkage of the chromophore phycoerythrobilin to phycoerythrins.
protein-phycoerythrobilin linkage
The linkage of the chromophore phytochromobilin to phycocyanin or allophycocyanin.
protein-phytochromobilin linkage
An enzyme complex that catalyzes the removal of the phosphate group from phosphomyosin. Composed of a PP1 catalytic subunit (PP1c/PPP1CB) and a myosin phosphatase targeting subunit (MYPT1/PPP1R12A).
myosin phosphatase complex
Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + retinol = adenosine 3',5'-bisphosphate + anhydroretinol.
retinol dehydratase activity
A heterodimeric protein complex that can stably associate with TATA-binding protein on promoters, thereby preventing the assembly of transcription factors TFIIA and TFIIB and leading to repression of RNA polymerase II transcription. The two subunits, NC2alpha (Drap1) and NC2beta (Dr1), dimerize through histone fold domains of the H2A/H2B type present in the amino termini.
negative cofactor 2 complex
Binding to a FH1 domain of a protein, a proline-rich domain, usually located in front of a FH2 domain.
FH1 domain binding
A protein complex that forms a transmembrane channel through which cations ions may pass in response to an intracellular cyclic nucleotide binding to the channel complex or one of its constituent parts.
intracellular cyclic nucleotide activated cation channel complex
Binding to a syntaxin-1 SNAP receptor.
syntaxin-1 binding
A protein complex consisting of a regulatory subunit (alpha-MPP) and a catalytic subunit (beta-MPP) that catalyzes the release of N-terminal targeting peptides from precursor proteins imported into the mitochondrion.
mitochondrial processing peptidase complex
A complex consisting of methionyl- and glutamyl-tRNA synthetases. The tRNA synthetases present in the complex bind to their cognate tRNAs more efficiently than they do as monomers.
methionyl glutamyl tRNA synthetase complex
Catalysis of the reaction: (R)-lipoyl-5'-AMP + L-lysyl- = (R)-N6-lipoyl-L-lysyl- + AMP + 2 H+.
lipoyltransferase activity
Binding to a SH3 domain (Src homology 3) of a protein, small protein modules containing approximately 50 amino acid residues found in a great variety of intracellular or membrane-associated proteins.
SH3 domain binding
Catalysis of the movement of phospholipids from one membrane bilayer leaflet to the other, by an ATP-independent mechanism.
phospholipid scramblase activity
A protein complex located in the mitochondrion. It contains flavin adenine dinucleotide (FAD) that, together with an acyl-CoA dehydrogenase, forms a system that oxidizes an acyl-CoA molecule and reduces ubiquinone and other acceptors in the mitochondrial electron transport system.
mitochondrial electron transfer flavoprotein complex
Binding to a Wnt-protein, a secreted growth factor involved in signaling.
Wnt-protein binding
Binding to a DEAD/H-box RNA helicase.
DEAD/H-box RNA helicase binding
Combining with a semaphorin, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
semaphorin receptor activity
Catalysis of the reaction: D-myo-inositol 1,3,4-trisphosphate + H2O = myo-inositol 1,3-bisphosphate + phosphate.
inositol-1,3,4-trisphosphate 4-phosphatase activity
Binding to an aryl hydrocarbon receptor.
aryl hydrocarbon receptor binding
Binding to vinculin, a protein found in muscle, fibroblasts, and epithelial cells that binds actin and appears to mediate attachment of actin filaments to integral proteins of the plasma membrane.
vinculin binding
Catalysis of the reaction: L-cysteine + O2 = 3-sulfino-L-alanine + H+.
cysteine dioxygenase activity
The gamma-carboxylation of peptidyl-glutamic acid; catalyzed by the vitamin K dependent gamma-glutamyl carboxylase.
peptidyl-glutamic acid carboxylation
The acetylation of the N-terminal aspartic acid of proteins; catalyzed by aspartate N-acetyltransferase.
N-terminal peptidyl-aspartic acid acetylation
The acetylation of a glutamine residue in protein to form the N5-methyl-L-glutamine derivative. The occurrence of this modification has not been confirmed. Its annotation in sequence databases is either due to the misidentification of 2-pyrrolidone-5-carboxylic acid, or to inappropriate homolog comparisons when proteolytic modification is more probable.
N-terminal peptidyl-glutamine acetylation
The acetylation of the N-terminal glutamic acid of proteins to form the derivate acetyl-glutamic acid.
N-terminal peptidyl-glutamic acid acetylation