NothingMuch/GO-Terms huggingface dataset:
The removal of phosphoric residues from peptidyl-O-phospho-L-threonine to form peptidyl-threonine.
peptidyl-threonine dephosphorylation
The removal of phosphoric residues from peptidyl-O-phospho-L-histidine to form peptidyl-histidine.
peptidyl-histidine dephosphorylation
The microtubule organizing center that forms as part of the meiotic cell cycle; functionally homologous to the animal cell centrosome.
meiotic spindle pole body
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trichostatin A stimulus.
cellular response to trichostatin A
The process whose specific outcome is the progression of the deltoid tuberosity over time, from its formation to the mature structure. The deltoid tuberosity is the region on the shaft of the humerus to which the deltoid muscle attaches. The deltoid tuberosity develops through endochondral ossification in a two-phase process; an initiating tendon-dependent phase, and a muscle-dependent growth phase.
deltoid tuberosity development
The series of events by which a muscle stretch stimulus is received by a cell and converted into a molecular signal.
detection of muscle stretch
The portion of the plasma membrane surrounding a microvillus of a rhabdomere.
rhabdomere microvillus membrane
The chemical reactions and pathways by which one-carbon (C1) units are transferred between tetrahydrofolate molecules, to synthesize other tetrahydrofolate molecules.
tetrahydrofolate interconversion
A small subcellular vesicle, surrounded by a membrane, in the pellicle of ciliate protozoans that discharges a mucus-like secretion.
mucocyst
Binding to a GAF protein domain.
GAF domain binding
A body present in the cytoplasm of some dinoflagellates, which is the source of bioluminescence; emits light on acidification in the presence of oxygen.
scintillon
The chemical reactions and pathways resulting in the breakdown of sucrose, which proceeds by phosphorylation of sucrose to form sucrose-6-phosphate. The subsequent actions of a hydrolase and a fructokinase generate fructose-6-phosphate and glucose-6-phosphate.
sucrose catabolic process to fructose-6-phosphate and glucose-6-phosphate
The outer, i.e. cytoplasm-facing, lipid bilayer of the cyanelle envelope.
cyanelle outer membrane
The process, occurring in the embryo, in which the anatomical structures of a skeletal limb joint are generated and organized. A skeletal limb joint is the connecting structure between the bones of a limb.
embryonic skeletal limb joint morphogenesis
Binding to a mediator complex. The mediator complex is a protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p; and a regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins.
mediator complex binding
The process of removing a malonyl group (CO-CH2-CO) from an malonylated lysine residue in a peptide or protein.
peptidyl-lysine demalonylation
The removal of a succinyl group (CO-CH2-CH2-CO) from a succinylated lysine residue in a peptide or protein.
peptidyl-lysine desuccinylation
A specialized cell-cell junction found between the interdigitating foot processes of the glomerular epithelium (the podocytes) in the vertebrate kidney, which is adapted for facilitating glomerular filtration.
slit diaphragm
The aggregation, arrangement and bonding together of a set of components to form a nephrocyte diaphragm, a specialized cell-cell junction found between nephrocytes of the insect kidney.
nephrocyte diaphragm assembly
The aggregation, arrangement and bonding together of a set of components to form a slit diaphragm, specialized cell-cell junction found between the interdigitating foot processes of the glomerular epithelium (the podocytes) in the vertebrate kidney, which is adapted for facilitating glomerular filtration.
slit diaphragm assembly
The process of transferring a fucosyl group to a serine or threonine residues in a protein acceptor molecule, to form an O-linked protein-sugar linkage.
protein O-linked fucosylation
Intramembranous ossification from the surface of a cartilage element as the perichondrium becomes a periosteum, without replacement of cartilage.
perichondral ossification
Ossification wherein bone tissue forms within ligamentous tissue.
ligamentous ossification
Ossification wherein bone tissue forms within tendonous tissue.
intratendonous ossification
The removal of tubulin heterodimers from the minus end of a microtubule.
minus-end specific microtubule depolymerization
The process by which an organism or tissue maintains a population of male germ-line stem cells.
male germ-line stem cell population maintenance
The process by which an organism or tissue maintains a population of female germ-line stem cells.
female germ-line stem cell population maintenance
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of inositol.
cellular response to inositol starvation
Binding to a kringle domain. Kringle domains are protein domains that fold into large loops stabilized by 3 disulfide linkages, and are important in protein-protein interactions with blood coagulation factors.
kringle domain binding
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycotoxin stimulus. A mycotoxin is a toxic chemical substance produced by fungi.
cellular response to mycotoxin
Catalysis of the reaction: 3-hexaprenyl-4-hydroxy-5-methoxybenzoic acid -> 2-hexaprenyl-6-methoxyphenol + CO2.
3-hexaprenyl-4-hydroxy-5-methoxybenzoic acid decarboxylase activity
A reversible switch of a cell from one phenotype to another that occurs upon infection of a host or host cell. For example, Candida albicans switches from a unicellular form to an invasive multicellular filamentous form upon infection of host tissue. Phenotypic switching begins with changes in cell morphology and altered gene expression patterns and ends when the morphology of a population of cells has reverted back to the default state, accompanied by altered expression patterns.
phenotypic switching in response to host
Catalysis of the reaction: 3-methoxy-4-hydroxy-5-decaprenylbenzoic acid -> 2-methoxy-6-decaprenylphenol + CO2.
3-methoxy-4-hydroxy-5-decaprenylbenzoic acid decarboxylase activity
A process that generates thiamine (vitamin B1) from derivatives of it without de novo synthesis.
thiamine salvage
Binding to a thiosulfate, a sulfur oxide that has formula O3S2.
thiosulfate binding
Catalysis of the reaction: 2'-deoxyribonucleoside diphosphate + glutaredoxin disulfide + H2O -> ribonucleoside diphosphate + glutaredoxin.
ribonucleoside-diphosphate reductase activity, glutaredoxin disulfide as acceptor
Definition: Catalysis of the reaction: 15-oxolipoxin A4 + NAD(P)H + H+ = 13,14-dihydro-15-oxolipoxin A4 + NAD(P)+.
13-lipoxin reductase activity
Catalysis of the reaction: indole + O2 + reduced  = H+ + H2O + indolin-2-one + oxidized .
indole-2-monooxygenase activity
Catalysis of the reaction: 2-hydroxy-2H-1,4-benzoxazin-3(4H)-one + O2 + reduced  = DIBOA + H+ + H2O + oxidized .
2-hydroxy-1,4-benzoxazin-3-one monooxygenase activity
The portion of the plasma membrane surrounding a muscle cell projection.
muscle cell projection membrane
Catalysis of the reaction: cholest-4-en-3-one + NADH + H+ + O2 = 26-hydroxycholest-4-en-3-one + NAD+ + H2O. This reaction involves the hydroxylation of the C26 carbon, followed by oxidation of the alcohol to the carboxylic acid via the aldehyde intermediate.
cholest-4-en-3-one 26-monooxygenase activity
Catalysis of the reaction: ent-isokaurene + O2 + NADPH + H+ = ent-2alpha-hydroxyisokaurene + H2O + NADP+.
ent-isokaurene C2-hydroxylase activity
Catalysis of the reaction: 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate + O2 + NADPH + H+ = 10beta,14beta-dihydroxytaxa-4(20),11-dien-5alpha-yl acetate + NADP+ + H2O.
taxoid 14-beta-hydroxylase activity
Catalysis of the reaction: abieta-7,13-dien-18-ol + NADPH + H+ + O2 = abieta-7,13-dien-18-al + NADP+ + 2 H2O. This is a two step reaction. The first step is: abieta-7,13-dien-18-ol + NADPH + H+ + O2 = abieta-7,13-dien-18,18-diol + + NADP+ + H2O. The second step is a spontaneous reaction: abieta-7,13-dien-18,18-diol = abieta-7,13-dien-18-al + H2O.
abieta-7,13-dien-18-ol hydroxylase activity
The process in which the mitotic cell cycle is halted during G2 phase as a result of deprivation of glucose.
mitotic G2 cell cycle arrest in response to glucose starvation
The removal of glucuronic acid from an acyl-glucuronide.
acyl deglucuronidation
The modification of an substrate by the conjugation of glucuronic acid to form an acyl-glucuronide (also called an acyl-glucuronoside).
acyl glucuronidation
Catalysis of the reaction: gallate + O2 = (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate.
gallate dioxygenase activity
Catalysis of the reaction: taxusin +  + O2 = 7beta-hydroxytaxusin +  + H2O. Also converts 2alpha-hydroxytaxusin to 2alpha,7beta-dihydroxytaxusin.
taxoid 7beta-hydroxylase activity
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a neutral pH (pH close to 7) stimulus. pH is a measure of the acidity or basicity of an aqueous solution.
cellular response to neutral pH
The directed movement of a peroxisome along a microtubule, mediated by motor proteins.
peroxisome transport along microtubule
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylamine stimulus.
cellular response to methylamine
The appearance of granulysin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
granulysin production
Self-propelled movement of an organism from one location to another through water, often by means of active fin movement.
swimming
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diuretic stimulus. A diuretic is an agent that promotes the excretion of urine through its effects on kidney function.
response to diuretic
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lapatinib stimulus.
response to lapatinib
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anticonvulsant stimulus, a drug used to prevent seizures or reduce their severity.
response to anticonvulsant
Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm in response to deprivation of glucose.
positive regulation of protein export from nucleus in response to glucose starvation
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-canavanine stimulus. L-canavanine is L-homoserine substituted at oxygen with a guanidino (carbamimidamido) group.
cellular response to L-canavanine
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iloperidone stimulus.
response to iloperidone
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ximelagatran stimulus.
response to ximelagatran
The process in which the anatomical structures of the umbilical cord are generated and organized. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta.
umbilical cord morphogenesis
The process in which a relatively unspecialized cell acquires specialized features of an ameloblast, a cylindrical epithelial cell in the innermost layer of the enamel organ.
ameloblast differentiation
The developmental growth that results in the increase in length of the embryonic heart tube. The embryonic heart tube is an epithelial tube that will give rise to the mature heart.
embryonic heart tube elongation
Catalysis of the reaction: S-adenosyl-L-methionine + adenine(2030) in 23S rRNA = S-adenosyl-L-homocysteine + rRNA containing N(6)-methyladenine(2030) in 23S rRNA.
23S rRNA (adenine(2030)-N(6))-methyltransferase activity
Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(1516) in 16S rRNA = N(2)-methylguanosine(1516) in 16S rRNA + S-adenosyl-L-homocysteine.
16S rRNA (guanine(1516)-N(2))-methyltransferase activity
Any process in which the SREBP-SCAP complex is maintained in the endoplasmic reticulum and prevented from moving elsewhere. The SREBP-SCAP complex is formed by the association of sterol regulatory element binding protein (SREBP) and SREBP-cleavage-activating protein (SCAP). In the absence of sterols, the SREBP-SCAP complex is packaged into COPII vesicles and travels to the Golgi apparatus to be processed. In the presence of sterols, the complex binds ER-resident proteins such as INSIG, which retain the complex in the ER.
SREBP-SCAP complex retention in endoplasmic reticulum
Any biological process involved in the maintenance of the steady-state number of hepatocytes within a population of cells. Hepatocytes are specialized epithelial cells of the liver that are organized into interconnected plates called lobules.
hepatocyte homeostasis
Any biological process involved in the maintenance of the steady-state number of epidermal stem cells within a population of cells.
epidermal stem cell homeostasis
The process in which a post-anal tail is generated and organized. A post-anal tail is a muscular region of the body that extends posterior to the anus. The post-anal tail may aid locomotion and balance.
post-anal tail morphogenesis
The specific behavior of an organism that combines cognitive functions and physical movement. For example, driving a car, throwing a ball, or playing a musical instrument.
psychomotor behavior
A developmental process, independent of morphogenetic (shape) change, that is required for a platelet to attain its fully functional state. A platelet is a non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation.
platelet maturation
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-cysteine stimulus. L-cysteine is an optically active form of cysteine having L-configuration.
cellular response to L-cysteine
Catalysis of the reaction: D-5-monosubstituted hydantoin = L-5-monosubstituted hydantoin.
hydantoin racemase activity
Catalysis of the reaction: 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide a = bacteriochlorophyllide a + 2 H+.
2-desacetyl-2-hydroxyethyl bacteriochlorophyllide a dehydrogenase activity
Catalysis of the reaction: L-tyrosine + S-adenosyl-L-methionine + reduced acceptor = 2-iminoacetate + 4-methylphenol + 5'-deoxyadenosine + L-methionine + acceptor + 2 H+.
2-iminoacetate synthase activity
A double layer of lipid molecules that surrounds an ascus, a capsule containing the sexual spores in some fungi.
ascus membrane
The ability of a photoreceptor to adjust to varying levels of light.
light adaption
Catalysis of the reaction: a reduced flavin + NAD+ = an oxidized flavin + 2 H+ + NADH.
flavin reductase (NADH) activity
Catalysis of the reaction: 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + FMNH2 + O2 = 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + FMN + H2O.
3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione monooxygenase activity
A ring-shaped structure that forms at the medial cortex of a symmetrically dividing cell at the onset of cytokinesis; composed of members of the conserved family of filament forming proteins called septins as well as septin-associated proteins.
medial cortex septin ring
A trimeric protein complex containing a H-NS homodimer and a Cnu monomer. In bacteria, this complex negatively regulates transcription of a range of genes.
H-NS-Cnu complex
Catalysis of the reaction: acetyl-CoA + oxalate = acetate + oxalyl-CoA.
acetyl-CoA:oxalate CoA-transferase
Prevention of degradation of tRNA molecules.
tRNA stabilization
Any process that decreases the stability of a tRNA molecule, making it more vulnerable to degradative processes.
tRNA destabilization
Catalysis of the reaction: ditrans,octacis-undecaprenyl phosphate + GDP-alpha-D-mannose = D-mannosyl undecaprenyl phosphate+ GDP.
ditrans, polycis-undecaprenyl-phosphate mannosyltransferase activity
Catalysis of the reaction: all-trans-undecaprenyl phosphate + GDP-alpha-D-mannose = D-mannosyl undecaprenyl phosphate + GDP.
all-trans-undecaprenyl-phosphate mannosyltransferase activity
Catalysis of the reaction: ATP + CMP = ADP + CDP.
CMP kinase activity
Catalysis of the reaction: ATP + undecaprenol + all-trans-undecaprenyl phosphate + ADP + H+.
all-trans undecaprenol kinase activity
Catalysis of the reaction: ethylnitronate + FMNH(2) + O2 = acetaldehyde + FMN + H2O + H+ + nitrite.
nitronate monooxygenase (FMN-linked) activity
Binding to a protein upon poly-ubiquitination formed by linkages between lysine residues at position 48 in the target protein.
K48-linked polyubiquitin modification-dependent protein binding
An Isw1 complex that binds DNA and has nucleosome-stimulated ATPase activity. In S. cerevisiae, contains an Isw1p ATPase subunit in complex with Ioc3p.
Isw1a complex
An Isw1 complex that binds DNA and has nucleosome-stimulated ATPase activity. In S. cerevisiae, contains an Isw1p ATPase subunit in complex with Ioc2p and Ioc4p.
Isw1b complex
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the accumulation of glucose-phosphate.
cellular response to glucose-phosphate stress
Catalysis of the reaction: L-methionine (S)-S-oxide + thioredoxin -> L-methionine + thioredoxin disulfide + H2O.
L-methionine-(S)-S-oxide reductase activity
A cytoplasmic, non-membrane bound granule of, at least, keratinocyte. Associated to keratin intermediate filaments and partially crosslinked to the cell envelope.
keratohyalin granule
Binding to a BLOC-2 complex, a protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules.
BLOC-2 complex binding
Catalysis of the reaction: L-tryptophan + H+ = CO2 + tryptamine.
L-tryptophan decarboxylase activity
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glyoxal stimulus.
cellular response to glyoxal
Binds to and stops, prevents or reduces the activity of peroxidase.
peroxidase inhibitor activity
The process that results in the return of an insulin receptor to an active state at the plasma membrane. An active state is when the receptor is ready to receive an insulin signal. Internalized insulin receptors can be recycled to the plasma membrane or sorted to lysosomes for protein degradation.
insulin receptor recycling
Combining with the fat-cell specific hormone leptin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
leptin receptor activity
Binding to a nodal protein, a member of the transforming growth factor-beta superfamily.
nodal binding
Interacting with an activin receptor complex to reduce the action of another ligand, the agonist. A receptor antagonist does not initiate signaling upon binding to a receptor, but instead blocks an agonist from binding to the receptor.
activin receptor antagonist activity
Binding to a neuregulin, a member of the EGF family of growth factors.
neuregulin binding
Combining with the glycoprotein thrombopoietin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
thrombopoietin receptor activity
Combining with the cytokine interleukin-17A and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
interleukin-17A receptor activity
Combining with auxin and transmitting the signal in the cell to initiate a change in cell activity. Auxin is a plant hormone (phytohormone).
auxin receptor activity
Combining with ethylene and transmitting the signal within the cell to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-histidine = ADP + a protein-L-histidine phosphate.
ethylene receptor histidine kinase activity
The process in which the proximal tubule of the pronephric nephron acquires its identity.
specification of pronephric proximal tubule identity
The process in which the distal tubule of the pronephric nephron acquires its identity.
specification of pronephric distal tubule identity
The process whose specific outcome is the progression of the pronephric sinus over time, from its formation to the mature structure. The pronephric sinus is an ill-defined capillary network that lies between the pronephric tubules.
pronephric sinus development
The process whose specific outcome is the progression of the nephrostome over time, from its formation to the mature structure. The nephrostome is the opening of the pronephros into the body cavity.
nephrostome development
The process in which the anatomical structures of the pronephric duct are generated and organized. The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the kidney.
pronephric duct morphogenesis
The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=1 symmetry. The T=1 capsid is composed of 12 pentameric capsomeres.
T=1 icosahedral viral capsid
The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=2 symmetry. The T=2 capsid is composed of 12 pentameric dimers.
T=2 icosahedral viral capsid
The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=3 symmetry. The T=3 capsid is composed of 12 pentameric and 20 hexameric capsomeres.
T=3 icosahedral viral capsid
The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with pseudo T=3 symmetry. The T=pseudo3 capsid is composed of 12 pentameric and 20 hexameric capsomeres.
T=pseudo3 icosahedral viral capsid
The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=4 symmetry. The T=4 capsid is composed of 12 pentameric and 30 hexameric capsomeres.
T=4 icosahedral viral capsid
The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=7 symmetry. The T=7 capsid is composed of 12 pentameric and 60 hexameric capsomeres.
T=7 icosahedral viral capsid