NothingMuch/GO-Terms huggingface dataset:
The series of events in which a low humidity stimulus is detected and converted into a molecular signal as a part of the sensory detection of low humidity.
detection of low humidity stimulus involved in sensory perception
A neuromuscular junction in which the target muscle cell is a skeletal muscle fiber.
neuromuscular junction of skeletal muscle fiber
A neuromuscular junction that functions in the excitation of somatic muscle myotubes, such as an arthropod somatic muscle cells.
excitatory neuromuscular junction of somatic myotube
A neuromuscular junction that functions in the inhibition of somatic muscle myotube contraction. Examples of somatic muscle myotubes include the somatic muscle cells of arthropods.
inhibitory neuromuscular junction of somatic myotube
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction that targets a skeletal muscle fiber.
neuromuscular junction development, skeletal muscle fiber
A spherical, electron dense, cytoplasmic structure that is involved in de novo assembly of centrioles.
deuterosome
Any process in which a protein complex is maintained in a specific location within the cytoplasm and is prevented from moving elsewhere.
maintenance of protein complex location in cytoplasm
The side of the Golgi membrane that faces the lumen.
lumenal side of Golgi membrane
The side (leaflet) of the Golgi membrane that faces the cytoplasm.
cytoplasmic side of Golgi membrane
A stable intercellular bridge between somatic cells. Examples include the intercellular bridges between ovarian follicle cells in insects and between imaginal disc cells in insects.
somatic ring canal
The side (leaflet) of the rough endoplasmic reticulum membrane that faces the lumen.
lumenal side of rough endoplasmic reticulum membrane
The side (leaflet) of the rough endoplasmic reticulum membrane that faces the cytoplasm.
cytoplasmic side of rough endoplasmic reticulum membrane
The side (leaflet) of the smooth endoplasmic reticulum membrane that faces the cytoplasm.
cytoplasmic side of smooth endoplasmic reticulum membrane
The side (leaflet) of the smooth endoplasmic reticulum membrane that faces the lumen.
lumenal side of smooth endoplasmic reticulum membrane
A transmembrane protein complex that consists of multiple methyl-accepting chemoreceptor protein subunits, a histidine kinase and a connector protein and which functions in the regulation of flagellar rotary motor activity in response to an external chemical stimulus.
methyl accepting chemotaxis protein complex
The volume enclosed within the membrane of a trans-Golgi network transport vesicle.
trans-Golgi network transport vesicle lumen
The side of the mycolate outer membrane that faces the cell wall peptidoglycan. It is rich in long-chain mycolic acids (hydroxylated branched-chain fatty acids) that are covalently linked to the cell wall peptidoglycan via an arabinogalactan network.
internal side of mycolate outer membrane
The side (leaflet) of the plastid thylakoid membrane that faces the lumen, and any proteins embedded in it or loosely bound to its surface.
lumenal side of plastid thylakoid membrane
A condensed form of chromatin that is associated with an inactivated sex chromosome and which is responsible for its inactivation.
condensed chromatin of inactivated sex chromosome
A sex chromosome that has not been inactivated.
active sex chromosome
A vocalisation behavior that is innate, i.e. that does not need to be learned in order to occur.
innate vocalization behavior
A vocalization behavior that is the result of learning.
learned vocalization behavior
The lipid bilayer surrounding a host synaptic vesicle.
host cell synaptic vesicle membrane
The leaflet the apical region of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
external side of apical plasma membrane
The side (leaflet) of the apical region of the plasma membrane that faces the cytoplasm.
cytoplasmic side of apical plasma membrane
A cup shaped specialization of the cytoskeleton that forms a thin layer located just below the apical mass of mature mucin secretory granules in the cytoplasm of goblet cells of the intestinal epithelium. It consists of an orderly network of intermediate filaments and microtubules. Microtubules are arranged vertically, like barrel staves, along the inner aspect of the theta. Intermediate filaments form two networks: an inner, basketlike network and an outer series of circumferential bundles resembling the hoops of a barrel.
goblet cell theca
A secretory granule that contains mucin.
mucin granule
The space between the membrane of an oocyte and a surrounding membranous structure (zona pellucida or perivitelline membrane).
perivitelline space
Catalysis of the reaction: L-Selenomethionine + H2O => Methaneselenol + Ammonia + 2-oxobutanoic acid.
selenomethionine gamma-lyase activity
Catalysis of the reaction: ATP + L-Selenomethionine + H2O => Orthophosphate + Diphosphate + Se-Adenosylselenomethionine.
selenomethionine adenosyltransferase activity
Catalysis of the reaction: R + Se-Adenosylselenomethionine => CH3-R + Se-Adenosyl-L-selenohomocysteine.
selenol Se-methyltransferase activity
Catalysis of the reaction: Se-Adenosyl-L-selenohomocysteine + H2O => Adenosine + Selenohomocysteine.
adenosylselenohomocysteinase activity
Catalysis of the reaction: L-Serine + Selenohomocysteine => L-Selenocystathionine + H2O.
selenocystathionine beta-synthase activity
Catalysis of the reaction: L-Selenocystathionine + H2O => L-Selenocysteine + NH3 + 2-Oxobutanoic acid.
selenocystathionine gamma-lyase activity
Catalysis of the reaction: Se-Methyl-L-selenocysteine + H2O => pyruvic acid + NH3 + Methaneselenol.
methylselenocysteine deselenhydrase activity
Catalysis of the reaction: methylselenol + H2O => H2Se + CH3OH.
methylselenol demethylase activity
Catalysis of the reaction: S-adenosyl-L-methionine + methaneselenol => S-adenosyl-L-homocysteine + dimethyl selenide.
methaneselenol methyltransferase activity
Catalysis of the reaction: S-adenosyl-L-methionine + hydrogen selenide => S-adenosyl-L-homocysteine + methaneselenol.
hydrogen selenide methyltransferase activity
Catalysis of the reaction: S-adenosyl-L-methionine + dimethyl selenide => S-adenosyl-L-homocysteine + trimethylselenonium.
dimethyl selenide methyltransferase activity
Catalysis of the reaction: ATP + H2SeO4 => diphosphate + adenylylselenate.
selenate adenylyltransferase (ATP) activity
Catalysis of the reaction: ATP + adenylylselenate => ADP + 3'-phosphoadenylylselenate.
adenylylselenate kinase activity
Catalysis of the reaction: ATP + L-selenomethionine + tRNA(Met) => AMP + diphosphate + selenomethionyl-tRNA(Met).
selenomethionine-tRNA ligase activity
Catalysis of the reaction: tRNASec + L-Ser + ATP = Ser-tRNASec + AMP + diphosphate.
selenocysteine-tRNA ligase activity
Catalysis of the reaction: Ser-tRNA(Sec) + ATP = Sep-tRNA(Sec) + ADP.
seryl-selenocysteinyl-tRNA kinase activity
Catalysis of the reaction: SeO3(2-) + 3NADPH + 5H+ = H2Se + 3NADP+ + 3H2O.
selenite reductase activity
Catalysis of the reaction: NADPH + H+ + CH3SeOH => NADP+ + CH3SeH + H2O.
methylselenol reductase activity
Catalysis of the reaction: NADPH + H+ + CH3SeO2H => NADP+ + CH3SeOH + H2O.
methylseleninic acid reductase activity
Catalysis of the reaction: phospho-L-arginyl- +H2O = L-arginyl- + phosphate.
protein arginine phosphatase activity
The removal of phosphate residues from peptidyl-N-phospho-arginine to form peptidyl-arginine.
peptidyl-N-phospho-arginine dephosphorylation
A process which results in the assembly, arrangement of constituent parts, or disassembly of a trans-Golgi network membrane.
trans-Golgi network membrane organization
Binding to a collagen fibril.
collagen fibril binding
Any laminin protein binding that occurs as part of cell-matrix adhesion.
laminin binding involved in cell-matrix adhesion
Any collagen binding that occurs as part of cell-matrix adhesion.
collagen binding involved in cell-matrix adhesion
Any integrin binding that occurs as part of the process of cell-matrix adhesion.
integrin binding involved in cell-matrix adhesion
Any cadherin binding that occurs as part of the process of cell-cell adhesion.
cadherin binding involved in cell-cell adhesion
Binding to a peptidyl-proline 4-dioxygenase.
peptidyl-proline 4-dioxygenase binding
The process by which a preexisting viral infection prevents a secondary infection with the same or a closely related virus. Typically some aspect of viral entry is inhibited, but post entry mechanisms have also been documented.
superinfection exclusion
The component of the neuronal dense core vesicle membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
extrinsic component of neuronal dense core vesicle membrane
A process by which the range of hosts which a virus can bind and infect is changed. Examples include phages that switch between types of fibers via the action of a virally encoded invertase.
viral tropism switching
Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the addition of a terminal nucleotide to an RNA molecule in the absence of a nucleic acid template.
template-free RNA nucleotidyltransferase
A non-membrane bound, electron dense structure associated that extends perpendicular to the presynaptic membrane in ribbon synapses. The ribbon's surface is studded with small particles to which synaptic vesicles tether via fine filaments. The tethered vesicles function as a pool, several fold greater than the docked pool available for fast release, which supports sustained release of vesicles. Synaptic ribbons may be plate like or spherical.
synaptic ribbon
An electron dense structure that anchors a synaptic ribbon to the presynaptic membrane.
arciform density
A ribbon synpase of an auditory hair cell of the cochlear. These ribbon synapses contain spherical synaptic ribbons and lack and arciform density.
cochlear hair cell ribbon synapse
A ribbon synapse between a retinal photoreceptor cell (rod or cone) and a retinal bipolar cell. These contain a plate-like synaptic ribbon.
photoreceptor ribbon synapse
A synapse between the Schaffer collateral axon of a CA3 pyramidal cell and a CA1 pyramidal cell.
Schaffer collateral - CA1 synapse
One of the giant synapses that form between the mossy fiber axons of dentate gyrus granule cells and the large complex spines of CA3 pyramidal cells. It consists of a giant bouton known as the mossy fiber expansion, synapsed to the complex, multiheaded spine (thorny excresence) of a CA3 pyramidal cell.
hippocampal mossy fiber to CA3 synapse
An excitatory synapse formed by the parallel fibers of granule cells synapsing onto the dendrites of Purkinje cells.
parallel fiber to Purkinje cell synapse
A synapse that uses glycine as a neurotransmitter.
glycinergic synapse
A synapse that uses dopamine as a neurotransmitter.
dopaminergic synapse
A synapse that uses noradrenaline as a neurotransmitter.
noradrenergic synapse
Any process that modulates the frequency, rate or extent of synaptic vesicle budding from presynaptic endocytic zone membrane.
regulation of synaptic vesicle budding from presynaptic endocytic zone membrane
Any process that modulates the frequency, rate or extent of neurotransmitter receptor localization to postsynaptic specialization membrane.
regulation of neurotransmitter receptor localization to postsynaptic specialization membrane
Any ryanodine-sensitive calcium-release channel activity that is involved in regulation of postsynaptic cytosolic calcium ion concentration.
ryanodine-sensitive calcium-release channel activity involved in regulation of postsynaptic cytosolic calcium levels
The action of a molecule that contributes to the structural integrity of a presynaptic actin cytoskeleton.
structural constituent of presynaptic actin cytoskeleton
A myofibril of a skeletal muscle fiber.
skeletal muscle myofibril
The symmetric division of a skeletal muscle satellite stem cell, resulting in two skeletal muscle satellite stem cells. This process is involved in amplification of the pool of these cells.
symmetric division of skeletal muscle satellite stem cell
The symmetric division of a male germline stem cell to produce two male germline stem cells. An example of this is found in mammalian spermatogonial stem cells, some proportion of which divide symmetrically, so amplifying the population. The choice between asymmetric and symmetric division in this case appears to be internal and stochastic.
male germline stem cell symmetric division
Any process by which the number of skeletal muscle satellite stem cells in a skeletal muscle is maintained during skeletal muscle regeneration. There are at least two mechanisms by which this is achieved. Skeletal muscle satellite stem cell asymmetric division ensures satellite stem cell numbers are kept constant. Symmetric division of these cells amplifies the number of skeletal muscle satellite stem cells.
skeletal muscle satellite stem cell maintenance involved in skeletal muscle regeneration
Any process that increases the force of heart muscle contraction.
positive regulation of the force of heart contraction
Any process that decreases the force of heart muscle contraction.
negative regulation of the force of heart contraction
Binds to and increases the activity of 1-phosphatidylinositol 4-kinase.
1-phosphatidylinositol 4-kinase activator activity
The slow, second phase of calcium ion-induced neurotransmitter release, via exocytosis, into the synaptic cleft. This depends on high affinity calcium sensors and decays slowly, typically with a decay constant of over 100ms. The underlying molecular mechanisms of this process are distinct from those of the earlier, fast phase of release.
slow, calcium ion-dependent exocytosis of neurotransmitter
Binding to a FXYD domain.
FYXD domain binding
The process by which seed dormancy is maintained by the presence of absisic acid.
maintenance of seed dormancy by absisic acid
The meiotic cell cycle phase in eukaryotes between meiotic prophase I and meiotic metaphase I. During meiotic prometaphase I, the nuclear envelope breaks down and one kinetochore forms per chromosome. Chromosomes attach to spindle microtubules and begin to move towards the metaphase plate.
meiotic prometaphase I
Binding to a member of the Tissue inhibitors of metalloproteinases (TIMPs) family. TIMPs are endogenous protein regulators of the matrix metalloproteinase (MMPs) family.
TIMP family protein binding
Binding to a member of the FBXO protein family. Members of this family have an F-box protein motif of approximately 50 amino acids that functions as a site of protein-protein interaction.
FBXO family protein binding
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) in response to the depolarization of one or more mitochondria.
response to mitochondrial depolarisation
A process that results in the assembly of a biofilm matrix.
biofilm matrix assembly
A process that results in the disassembly of a biofilm matrix.
biofilm matrix disassembly
Binding to a 7-methylguanosine (m7G) group or derivative located at the 5' end of an mRNA molecule.
mRNA cap binding
A process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell induced by the evoked release of many vesicles of excitatory neurotransmitter at the synapse.
evoked excitatory postsynaptic potential
A process that hyerpolarizes a postsynaptic membrane relative to its resting potential. This has an inhibitory effect on the post-synaptic cell, moving the membrane potential away from the firing threshold.
hyperpolarization of postsynaptic membrane
A process that depolarizes a postsynaptic membrane relative to its resting potential. This has an excitatory effect on the post-synaptic cell, moving the membrane potential towards the firing threshold.
depolarization of postsynaptic membrane
A protein complex that spans the synaptic cleft and has parts in both the pre- and post-synaptic membranes.
trans-synaptic protein complex
Combining with a member of the bone morphogenetic protein (BMP) family, and transmitting a signal across the plasma membrane to initiate a change in cell activity.
BMP receptor activity
The membrane of the endoplasmic reticulum tubular network.
endoplasmic reticulum tubular network membrane
Uptake of folic into the blood by absorption from the small intestine.
intestinal folate absorption
A recycling endosome that is organized around the microtubule organizing center, close to the nucleus. This is the main recycling endosome of most cells. It receives input from the Golgi as well as recycled molecules from early endosomes.
peri-centrosomal recycling endosome
A cellular protein localization process in which a protein is transported to, or maintained at, the site of cell division following cytokinesis.
protein localization to cell division site after cytokinesis
Any process that reduces or removes the toxicity of cadmium cations in a cell. These include transport of cadmium cations away from sensitive areas and to compartments or complexes whose purpose is sequestration.
cellular detoxification of cadmium ion
The component of the synaptic vesicle membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
extrinsic component of synaptic vesicle membrane
A bundle of hundreds of cross-linked actin filaments (an actin cable), that is the supporting structure of a stereocilium. Filaments are oriented such that the the plus (barbed) ends are at the tip of the protrusion and are capped by a tip complex which bridges to the plasma membrane.
actin filament bundle of stereocilium
A parallel bundle of actin filaments that is part of filopodium. Filaments are oriented such that the plus (barbed) ends are at the tip of the protrusion, capped by a tip complex.
actin filament bundle of filopodium
The directed movement of the nucleus by pushing forces exerted by polymerization of backward-extending microtubules.
nuclear migration by microtubule mediated pushing forces
The fusion of the membrane of a multivesicular body with the apical plasma membrane, resulting in release of exosomes from the cell.
multivesicular body fusion to apical plasma membrane
The increase in size or mass of an intramembranous bone that contributes to the shaping of the bone.
intramembranous bone growth
Propagation of an action potential in a neuron, from its site of initiation (typically the axon hillock) towards the soma.
neuronal action potential back-propagation
A microvesicle of the epididymal fluid, from which spermatozoa acquire membrane proteins.
epididymosome
Any process that modifies the structure of a dendritic spine.
modification of dendritic spine
The component of the presynaptic active zone membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
extrinsic component of presynaptic active zone membrane
The component of the postsynaptic endocytic zone membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
extrinsic component of postsynaptic endocytic zone
The component of the presynaptic endocytic zone membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
extrinsic component of presynaptic endocytic zone membrane
The lipid bilayer surrounding the spine apparatus.
spine apparatus membrane
The volume enclosed by the spine apparatus membrane.
spine apparatus lumen
Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a Purkinje myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.
regulation of Purkinje myocyte action potential
Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell contributing to the regulation of its contraction.
regulation of cardiac muscle cell action potential involved in regulation of contraction
The action of a molecule that contributes to the structural integrity of a postsynaptic density.
structural constituent of postsynaptic density
Modulation of synaptic transmission by cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by nitric oxide.
retrograde trans-synaptic signaling by nitric oxide, modulating synaptic transmission
The process by which a virion attaches to a the host cell flagellum. Some DNA bacterial viruses use flagella to attach to the host cell. This contact with the flagellum facilitates concentration of phage particles around the entry receptor on the bacterial cell surface.
virion attachment to host cell flagellum
The directed movement of organelles or molecules along microtubules in a dendrite from the postsynapse towards the cell body.
retrograde dendritic transport
The actin cytoskeleton that is part of a dendritic spine.
actin cytoskeleton of dendritic spine
Cell-cell signaling from presynapse to postynapse, across the synaptic cleft, mediated by nitric oxide.
anterograde trans-synaptic signaling by nitric oxide
Cell-cell signaling from presynapse to postynapse, across the synaptic cleft, mediated by a trans-synaptic protein complex.
anterograde trans-synaptic signaling by trans-synaptic protein complex
Vesicle-mediated transport of a neurotransmitter receptor complex from the postsynaptic membrane to the postsynaptic early endosome.
neurotransmitter receptor transport postsynaptic membrane to endosome
The directed movement of a neurotransmitter receptor complex along microtubules in nerve cell dendrites towards the postsynapse.
anterograde dendritic transport of neurotransmitter receptor complex
The directed movement of mitochondria along microtubules in dendrites towards the postsynapse and away from the cell body.
anterograde dendritic transport of mitochondrion
The action of a molecule that contributes to the structural integrity of a postsynaptic actin cytoskeleton.
structural constituent of postsynaptic actin cytoskeleton
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins in the postsynaptic actin cytoskeleton.
postsynaptic actin cytoskeleton organization
Synaptic transmission that results in an excitatory postsynaptic potential.
excitatory chemical synaptic transmission
Synaptic transmission that results in an inhibitory postsynaptic potential.
inhibitory chemical synaptic transmission
A synapse consisting of a single presynapse and multiple postsynapses. These postsynapses may come from the same cell of from different cells. Polyadic synapses are common in arthropod and nematode central nervous systems.
polyadic synapse
A neuron to neuron synapse that lacks an electron dense postsynaptic specialization, uses GABA as a neurotransmitter and whose activity results in inhibitory postsynaptic potentials.
symmetric, GABA-ergic, inhibitory synapse
A T-shaped presynpatic density. These are common in arhropod central nervous systems.
T-bar
Any process that regulates the modification of synaptic structure and as a result regulates synaptic transmission.
regulation of modification of synapse structure, modulating synaptic transmission
The series of molecular signals initiated by glutamate binding to an NMDA-selective glutamate receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex, and ending with the regulation of a downstream cellular process, e.g. transcription.
NMDA selective glutamate receptor signaling pathway