NothingMuch/GO-Terms huggingface dataset:
The directed, sodium-independent, movement of leukotrienes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Leukotrienes are linear C20 endogenous metabolites of arachidonic acid (icosa-5,8,11,14-tetraenoic acid) containing a terminal carboxy function and four or more double bonds (three or more of which are conjugated) as well as other functional groups.
sodium-independent leukotriene transport
The directed, sodium-independent, movement of prostaglandins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
sodium-independent prostaglandin transport
The directed, sodium-independent, movement of thromboxanes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A thromboxane is any of a class of oxygenated oxane derivatives, originally derived from prostaglandin precursors in platelets, that stimulate aggregation of platelets and constriction of blood vessels.
sodium-independent thromboxane transport
The process that gives rise to the beak. This process pertains to the initial formation of a structure from unspecified parts. The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary rhamphotheca, mandibular rhamphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus.
beak formation
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitric oxide stimulus.
cellular response to nitric oxide
A protein complex composed of two identical immunoglobulin heavy chains of the IgW isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgW immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
IgW immunoglobulin complex
A protein complex composed of two identical immunoglobulin heavy chains of the IgX isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgX immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
IgX immunoglobulin complex
A protein complex composed of two identical immunoglobulin heavy chains of the IgY isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgY immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
IgY immunoglobulin complex
Binding to a CAP-Gly domain of a protein. The CAP_Gly domain is a conserved, glycine-rich domain of about 42 residues found in some cytoskeleton-associated proteins, and features a novel protein fold containing three beta-sheets.
CAP-Gly domain binding
Binding to a protein upon poly-ubiquitination formed by linkages between lysine residues at position 11 in the target protein.
K11-linked polyubiquitin modification-dependent protein binding
Binding to a protein upon poly-ubiquitination formed by linkages between lysine residues at position 6 in the target protein.
K6-linked polyubiquitin modification-dependent protein binding
A ubiquitin ligase complex that catalyzes linear head-to-tail polyubiquitin conjugation on its targets. In human the complex consists of RBCK1, RNF31 and SHARPIN, and has an MW of approximately 600 kDa, suggesting a heteromultimeric assembly of its subunits. LUBAC stands for Linear Ubiquitin Chain Assembly Complex.
LUBAC complex
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin D stimulus.
cellular response to prostaglandin D stimulus
A replication fork arrest process that contributes to the termination of DNA replication.
replication fork arrest involved in DNA replication termination
An axoneme part that is found in the flagella of mammalian sperm and is located in the middle piece between the outer dense fibers (on the concave side of outer dense fibers as seen in cross-section).
satellite fibril
Any process that modulates the rate or extent of fever generation via regulation of the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin.
regulation of fever generation by regulation of prostaglandin biosynthesis
Any process that modulates the rate or extent of fever generation via regulation of the frequency, rate or extent of the regulated release of a prostaglandin from a cell.
regulation of fever generation by regulation of prostaglandin secretion
Any process that increases the rate or extent of fever generation via positive regulation of the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin.
positive regulation of fever generation by positive regulation of prostaglandin biosynthesis
Any process that increases the rate or extent of fever generation via positive regulation of the frequency, rate or extent of the regulated release of a prostaglandin from a cell.
positive regulation of fever generation by positive regulation of prostaglandin secretion
A protein complex contains the proteins FANCM and MHF, or their orthologs, plays an essential role in DNA remodeling, protects replication forks, and is conserved in eukaryotes.
FANCM-MHF complex
Binding to an HMG box domain, a protein domain that consists of three helices in an irregular array. HMG-box domains are found in one or more copies in HMG-box proteins, which form a large, diverse family involved in the regulation of DNA-dependent processes such as transcription, replication, and strand repair, all of which require the bending and unwinding of chromatin.
HMG box domain binding
An actin filament severing process that results in the removal of actin filament branches specifically at the branch points.
actin filament debranching
The chemical reactions and pathways that result in the breakdown of macromolecules that form part of a cell wall, and contributes to the breakdown of the fungal-type cell wall.
cell wall macromolecule catabolic process involved in fungal-type cell wall disassembly
Binding to a beta-endorphin receptor.
beta-endorphin receptor binding
Binding to a corazonin receptor.
corazonin receptor binding
Binding to a neuropeptide F receptor.
neuropeptide F receptor binding
Binding to a proctolin receptor.
proctolin receptor binding
Binding to a tachykinin receptor.
tachykinin receptor binding
Binding to a 14-3-3 protein. A 14-3-3 protein is any of a large family of approximately 30kDa acidic proteins which exist primarily as homo- and heterodimers within all eukaryotic cells, and have been implicated in the modulation of distinct biological processes by binding to specific phosphorylated sites on diverse target proteins, thereby forcing conformational changes or influencing interactions between their targets and other molecules. Each 14-3-3 protein sequence can be roughly divided into three sections: a divergent amino terminus, the conserved core region and a divergent carboxy-terminus. The conserved middle core region of the 14-3-3s encodes an amphipathic groove that forms the main functional domain, a cradle for interacting with client proteins.
14-3-3 protein binding
Determination of the asymmetric location of the intestine loops with respect to the left and right halves of the organism.
determination of intestine left/right asymmetry
Determination of the asymmetric location of the stomach with respect to the left and right halves of the organism.
determination of stomach left/right asymmetry
Determination of the asymmetric location of the liver with respect to the left and right halves of the organism.
determination of liver left/right asymmetry
Release of neurotransmitter at the synapse that lasts for just a few milliseconds after action potential invasion.
synchronous neurotransmitter secretion
Release of neurotransmitter at the synapse that persists for tens to hundreds of milliseconds after action potential invasion.
asynchronous neurotransmitter secretion
A nuclear body that contains proteins involved in pre-mRNA 3'-end cleavage and polyadenylation, such as DDX1, CSTF2 and CPSFs, as well as the transcription factors TFIIE and TFIIF. Cleavage bodies are localized adjacent to Cajal bodies and are involved in mRNA3'-end processing.
cleavage body
The addition of an acetyl group to the lysine 40 residue of alpha-tubulin.
alpha-tubulin acetylation
Replication fork processing that involves the unwinding of blocked forks to form four-stranded structures resembling Holliday junctions, which are subsequently resolved.
replication fork reversal
Binding to an Arp2/3 complex, a protein complex that contains two actin-related proteins, Arp2 and Arp3, and five novel proteins (ARPC1-5).
Arp2/3 complex binding
A nucleotide-excision repair complex that is involved in damage sensing during global genome nucleotide excision repair (GG-NER). It is part of the pre-incision (or initial recognition) complex bound to sites of DNA damage. In human, it is composed of XPC, RAD23B and CETN2.
XPC complex
A transcription factor complex that consists of a heterodimer of the bHLH-ZIP proteins Myc and Max.
Myc-Max complex
The removal of one or more ubiquitin groups from a protein as part of a process of ubiquitin-dependent protein catabolism.
protein deubiquitination involved in ubiquitin-dependent protein catabolic process
The modification process that results in the conversion of methionine charged on a tRNA(fMet) to N-formyl-methionine-tRNA(fMet).
conversion of methionyl-tRNA to N-formyl-methionyl-tRNA
The modification process that results in the conversion of O-phosphoserine charged on a tRNA(Cys) to cysteinyl-tRNA.
conversion of O-phosphoseryl-tRNA to cysteinyl-tRNA
The directed movement of substances from recycling endosomes to the Golgi.
recycling endosome to Golgi transport
Locomotion in a multicellular organism, i.e. self-propelled movement of a multicellular organism from one location to another.
multicellular organismal locomotion
Catalysis of the reaction: galactosyl-glucosyl3-heptosyl3-KDO2-lipid A-bisphosphate + ADP-L-glycero-beta-D-manno-heptose = lipid A-core + ADP + H+.
lipid A-core heptosyltransferase activity
Catalysis of the reaction: 2 a peptidoglycan dimer (tetrapeptide) + 3 H2O = a peptidoglycan tetramer with L,D cross-links (L-Lys-D-Asn-L-Lys) + di-trans,poly-cis-undecaprenyl diphosphate + 4 D-alanine.
peptidoglycan L,D-transpeptidase activity
Cell gliding that results from the actions of cell surface adhesin proteins that are propelled by membrane motor proteins.
cell surface adhesin-mediated gliding motility
The dormancy process that results in exit from reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli.
exit from reproductive diapause
The dormancy process that results an organism remaining in reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli.
maintenance of reproductive diapause
Any process that modulates the frequency, rate or extent of mesenchymal stem cell proliferation and contributes to the shaping of a nephron.
regulation of mesenchymal stem cell proliferation involved in nephron morphogenesis
The process whose specific outcome is the progression of the inner stripe over time, from its formation to the mature structure. The inner stripe is a deep, centrally located portion of the renal outer medulla and is traversed by thin descending and thick ascending portions of the loops of Henle.
inner stripe development
The process whose specific outcome is the progression of the outer stripe over time, from its formation to the mature structure. The outer stripe is the region of the kidney outer medulla that lies just below the cortex. The proximal straight tubules (S3) characterize this region.
outer stripe development
The process whose specific outcome is the progression of the outer medullary collecting duct over time, from its formation to the mature structure. The outer medullary collecting duct is the portion of the collecting duct that lies in the renal outer medulla.
outer medullary collecting duct development
The process whose specific outcome is the progression of the inner medullary collecting duct over time, from its formation to the mature structure. The inner medullary collecting duct is the portion of the collecting duct that lies in the renal inner medulla.
inner medullary collecting duct development
The process whose specific outcome is the progression of the kidney stroma over time, from its formation to the mature structure. The kidney stroma is the mesenchyme of the mature kidney.
kidney stroma development
The process in which the ureteric bud grows along its axis and contributes to the formation of the metanephros.
ureteric bud invasion
Any process that reduces the frequency, rate or extent of branch elongation involved in ureteric bud branching, the growth of a branch of the ureteric bud along its axis.
negative regulation of branch elongation involved in ureteric bud branching
A wavelike sequence of involuntary muscular contraction and relaxation that passes along the ureter, impelling the contents onwards. The ureter is one of a pair of thick-walled tubes that transports urine from the kidney pelvis to the urinary bladder.
ureteric peristalsis
Any process that increases the rate or extent of the developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct.
positive regulation of ureteric bud formation
Any process that increases the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros.
positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
The developmental process pertaining to the initial formation of the head kidney. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney.
head kidney formation
A developmental process, independent of morphogenetic (shape) change, that is required for the head kidney to attain its fully functional state. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney.
head kidney maturation
The process in which the anatomical structures of a nephrogenic mesenchymal tissue are generated and organized. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron.
nephrogenic mesenchyme morphogenesis
The multiplication or reproduction of cells, resulting in the expansion of a metanephric mesenchymal cell population.
metanephric mesenchymal cell proliferation involved in metanephros development
The multiplication or reproduction of cells, resulting in the expansion of a condensed mesenchymal cell population. A condensed mesenchymal cell population is a population of adherent mesenchymal cells.
condensed mesenchymal cell proliferation
The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the metanephros as it progresses from its formation to the mature state.
metanephric mesenchymal cell differentiation
The process in which the tubules of the anterior mesonephros acquire their identity.
specification of anterior mesonephric tubule identity
The process in which the tubules of the posterior mesonephros acquire their identity.
specification of posterior mesonephric tubule identity
The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the renal vesicle progenitor cells of the kidney as it progresses from its formation to the mature state. A renal vesicle progenitor cell is a cell that will give rise to terminally differentiated cells of the renal vesicle without self-renewing.
renal vesicle progenitor cell differentiation
The process in which the metanephric cap acquires its identity.
metanephric cap specification
The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell in the urothelium. The urothelium is the epithelial tube of the ureter.
ureter epithelial cell differentiation
The process whose specific outcome is the progression of smooth muscle in the metanephros over time, from its formation to the mature structure.
metanephric smooth muscle tissue development
The process whose specific outcome is the progression of the metanephric cortex over time, from its formation to the mature structure. The metanephric cortex is the outer region of the metanephros.
metanephric cortex development
The process whose specific outcome is the progression of a metanephric ascending thin limb over time, from its formation to the mature structure. The metanephric ascending thin limb is a segment of a nephron tubule in the metanephros lying in the inner medulla that is permeable to ions but not to water and has a simple epithelium; active transepithelial solute transport is absent.
metanephric ascending thin limb development
The process whose specific outcome is the progression of the metanephric cortical collecting duct over time, from its formation to the mature structure. The metanephric cortical collecting duct is the portion of the metanephric collecting duct that resides in the renal cortex.
metanephric cortical collecting duct development
The process whose specific outcome is the progression of the metanephric early distal convoluted tubule over time, from its formation to the mature structure. The metanephric early distal convoluted tubule contains metanephric DCT cells and is vasopressin-insensitive.
metanephric early distal convoluted tubule development
The process whose specific outcome is the progression of the metanephric late distal convoluted tubule over time, from its formation to the mature structure. The metanephric late distal convoluted tubule contains metanephric DCT cells and intercalated (IC) alpha and beta cells and is vasopressin-sensitive.
metanephric late distal convoluted tubule development
The process whose specific outcome is the progression of the metanephric long descending thin limb bend over time, from its formation to the mature structure. The metanephric long descending thin limb bend is a part of the descending thin limb of a long nephron that lies beyond the prebend segment in the metanephros.
metanephric long descending thin limb bend development
The process whose specific outcome is the progression of the metanephric macula densa over time, from its formation to the mature structure. The metanephric macula densa is an area of specialized cells in the distal tubule of the metanephros that makes contact with the vascular pole of the glomerulus.
metanephric macula densa development
The process whose specific outcome is the progression of the metanephric prebend segment over time, from its formation to the mature structure. The metanephric prebend segment is a part of the metanephric descending thin limb that lies before the bend and exhibits permeabilities characteristic of the ascending limb, especially negligible water permeability.
metanephric prebend segment development
The process whose specific outcome is the progression of a metanephric juxtaglomerulus cell over time, from its formation to the mature structure.
metanephric juxtaglomerulus cell development
The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric juxtaglomerulus cell.
metanephric juxtaglomerulus cell fate commitment
The process whose specific outcome is the progression of a glomerular mesangial cell in the metanephros over time, from its formation to the mature structure.
metanephric glomerular mesangial cell development
The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular mesangial cell.
metanephric glomerular mesangial cell fate commitment
The multiplication or reproduction of intraglomerular glomerular mesangium cells in the metanephros by cell division, resulting in the expansion of their population. Intraglomerular mesangial cells are specialized pericytes located among the glomerular capillaries within a renal corpuscle of a kidney. They are required for filtration, structural support and phagocytosis.
metanephric intraglomerular mesangial cell proliferation
The process whose specific outcome is the progression of the metanephric glomerular endothelium over time, from its formation to the mature structure. The metanephric glomerular endothelium is an epithelial tissue that covers the internal surfaces of the glomerulus of the metanephros.
metanephric glomerular endothelium development
The regionalization process in which the identity of the metanephric capsule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
metanephric capsule specification
The process whose specific outcome is the progression of the metanephric short descending thin limb over time, from its formation to the mature structure. The metanephric short descending thin limb is the descending thin limb of a short nephron in the metanephros that has a squamous epithelial morphology.
metanephric short descending thin limb development
The process whose specific outcome is the progression of the metanephric glomerular basement membrane over time, from its formation to the mature structure. The metanephric glomerular basement membrane is the basal laminal portion of the metanephric glomerulus which performs the actual filtration.
metanephric glomerular basement membrane development
The process that gives rise to a metanephric glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts.
metanephric glomerular capillary formation
The morphogenetic process in which the renal epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to the shaping of a nephron in the metanephros.
convergent extension involved in metanephric nephron morphogenesis
The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell that contributes to the shaping of a nephronin the metanephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.
mesenchymal stem cell differentiation involved in metanephric nephron morphogenesis
A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephric renal vesicle.
mesenchymal to epithelial transition involved in metanephric renal vesicle formation
The orderly movement of epithelial cells within a renal tubule that contributes to metanephric distal tubule morphogenesis.
epithelial cell migration involved in metanephric distal tubule morphogenesis
The orderly movement of epithelial cells within a renal tubule that contributes to metanephric proximal tubule morphogenesis.
epithelial cell migration involved in metanephric proximal tubule morphogenesis