NothingMuch/GO-Terms huggingface dataset:
Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a single-subunit-type mitochondrial RNA polymerase-specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
mitochondrial single subunit type RNA polymerase activity
Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a single subunit type plastid RNA polymerase specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
plastid single subunit type RNA polymerase activity
Binding to a RNA region within the transcript that regulates the transcription of a gene, cistron, or operon.
transcription regulatory region RNA binding
Binding to a general RNA polymerase II transcription factor of the TFIIB class, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II.
TFIIB-class transcription factor binding
The aggregation, arrangement and bonding together of proteins, DNA, and RNA molecules to form a protein-DNA-RNA complex.
protein-DNA-RNA complex assembly
The acquisition, loss, or modification of macromolecules within a protein-DNA-RNA complex, resulting in the alteration of an existing complex.
protein-DNA-RNA complex remodeling
Binding to an RNA polymerase III transcription factor of the TFIIIA class, one of the factors involved in formation of the preinitiation complex (PIC) at RNA polymerase III promoters.
TFIIIA-class transcription factor binding
Binding to an RNA polymerase II intronic DNA sequence that regulates the transcription of the transcript it is contained within.
RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding
Any process involved in the selection of the specific location within the template strand of an RNA polymerase III promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript.
transcriptional start site selection at RNA polymerase III promoter
Replication of circular DNA following excision from the chromosome; replication of extrachromosomal circular DNA generally occurs independently of chromosomal replication.
replication of extrachromosomal circular DNA
Enables the transfer of glycerophosphodiesters from one side of a membrane to the other. Glycerophosphodiesters are small molecules composed of glycerol-3-phosphate and an alcohol, for example, glycerophosphoinositol.
glycerophosphodiester transmembrane transporter activity
The process in which a glycerophosphodiester is transported across a membrane. Glycerophosphodiesters are small molecules composed of glycerol-3-phosphate and an alcohol, for example, glycerophosphoinositol.
glycerophosphodiester transmembrane transport
Naturally occurring peptide that is an opioid (any non-alkaloid having an opiate-like effect that can be reversed by naloxone or other recognized morphine antagonist). These include Leu- and Met-enkephalin, dynorphin and neoendorphin, alpha, beta, gamma and delta endorphins formed from beta-lipotropin, various pronase-resistant peptides such as beta casamorphin, and other peptides whose opiate-like action seems to be indirect.
opioid peptide activity
The posttranslational conversion of C-terminal glycine-extended peptides to C-terminal alpha-amidated peptides. Occurs to over half of all peptide hormones to give bioactive peptides. This is a two step process catalyzed by a peptidyl-glycine alpha-hydroxylating monooxygenase and a peptidyl-alpha-hydroxyglycine alpha-amidating lyase. In some organisms, this process is catalyzed by two separate enzymes, whereas in higher organisms, one polypeptide catalyzes both reactions.
peptide amidation
A type of plasma membrane that has been modified through addition of distinct intracellular and extracellular components, including ceramide, found in cornifying epithelial cells (corneocytes).
cornified envelope
Protein complex forming the elongated portion of the radial spoke between the base which binds to the A-tubule of each microtubule outer doublet and the neck which connects to the spoke head within the ciliary or flagellum axoneme.
radial spoke stalk
Disruption of theca cell layer releasing follicular fluid and/or the oocyte.
ovarian follicle rupture
Increase in size of primordial follicles including proliferation and shape changes of granulosa and/or theca cells until oocyte is surrounded by one layer of cuboidal shaped granulosa cells (primary follicle).
initiation of primordial ovarian follicle growth
Increase in size of follicles surrounded by two or more layers of granulosa cells up to the onset of antrum formation.
preantral ovarian follicle growth
Association of oocytes with supporting epithelial granulosa cells to form primordial follicles.
ovarian follicle endowment
A periodic process in which immature ovarian follicles degenerate and are subsequently re-absorbed.
ovarian follicle atresia
A metabolic pathway by which 3-methyl branched fatty acids are degraded. These compounds are not degraded by the normal peroxisomal beta-oxidation pathway, because the 3-methyl blocks the dehydrogenation of the hydroxyl group by hydroxyacyl-CoA dehydrogenase. The 3-methyl branched fatty acid is converted in several steps to pristenic acid, which can then feed into the beta-oxidative pathway.
fatty acid alpha-oxidation
Combining with a phorbol ester and transmitting the signal by a mechanism independent of kinase activity.
non-kinase phorbol ester receptor activity
The directed movement of a medium-chain fatty acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A medium-chain fatty acid has an aliphatic tail containing 6 to 12 carbons.
medium-chain fatty acid transport
Combining with gut peptide YY to initiate a change in cell activity.
peptide YY receptor activity
Combining with pancreatic polypeptide PP to initiate a change in cell activity.
pancreatic polypeptide receptor activity
Combining with urotensin II to initiate a change in cell activity.
urotensin II receptor activity
A G protein-coupled receptor that is activated by trans-1-aminocyclopentane-1,3-dicarboxylic acid (t-ACPD) and inhibits adenylate cyclase activity.
group II metabotropic glutamate receptor activity
A G protein-coupled receptor that is activated by L-AP-4 and inhibits adenylate cyclase activity.
group III metabotropic glutamate receptor activity
A conditioned aversion to a specific chemical compound as a result of that compound being coupled with a noxious stimulus.
conditioned taste aversion
Post-transcriptional addition of the terminal 3' CCA sequence to a tRNA which does not encode this sequence within the primary transcript. CCA addition proceeds by the sequential addition of CTP, CTP, and then ATP to the 3' end of the tRNA, yielding a diphosphate with each nucleotide addition.
tRNA 3'-terminal CCA addition
Maintains the phosphorylation state of certain molecules by associating with them and preventing them from associating with active phosphatases, and thus inhibiting the enzyme activity without interacting with the enzyme. Often pertains to proteins belonging to dual-specificity phosphatase family but lacking critical active site residues.
pseudophosphatase activity
The regulated release of gastric acid induced by the interaction of histamine with H2 type receptor receptors with subsequent activation of adenylate cyclase and elevation of intracellular cyclic AMP.
histamine-induced gastric acid secretion
The regulated release of gastric acid by parietal cells in response to acetylcholine.
acetylcholine-induced gastric acid secretion
The modification process that results in the conversion of serine, carried by a specialized tRNA(ser) (which can read a UGA anticodon), to selenocysteine.
conversion of seryl-tRNAsec to selenocys-tRNAsec
The modification process that results in the conversion of lysine, carried by a specialized lysine-accepting tRNA (possessing a CUA anticodon), to pyrrolysine (a lysine with an amide linkage to a (4R,5R)-4-substituted pyrroline-5-carboxylate).
conversion of lysyl-tRNA to pyrrolysyl-tRNA
A structure found in a female mammalian cell containing an unpaired X chromosome that has become densely heterochromatic, silenced and localized at the nuclear periphery.
Barr body
A structure found in a male mammalian spermatocyte containing an unpaired X chromosome that has become densely heterochromatic, silenced and localized at the nuclear periphery.
XY body
The morphogenetic process in which the anatomical structures of the larval eye in Drosophila are generated and organized. The larval eye in Drosophila is a relatively simple sensory system composed of Bolwig's organs: two clusters, each composed of 12 photoreceptor cells from which axons extend in a single fascicle to the brain.
Bolwig's organ morphogenesis
The process in which individual somites establish identity during embryogenesis.
somite specification
The directed movement of beta-alanine, 3-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
beta-alanine transport
Binding to phosphatidylserine, a class of glycophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of L-serine.
phosphatidylserine binding
Binding to a J-chain-containing polymeric immunoglobulin of the IgA or IgM isotypes.
polymeric immunoglobulin binding
Binding to an immunoglobulin of the IgM isotype.
IgM binding
Combining with a J-chain-containing polymeric immunoglobulin of the IgA or IgM isotypes via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
polymeric immunoglobulin receptor activity
The cell fate commitment of precursor cells that will become inner cell mass cells.
inner cell mass cell fate commitment
The morphogenesis of cells in the inner cell mass.
inner cell mass cellular morphogenesis
The proliferation of cells in the inner cell mass.
inner cell mass cell proliferation
The hatching of the cellular blastocyst from the zona pellucida.
blastocyst hatching
Binding to a C1q complex, a component of the classical complement cascade.
complement component C1q complex binding
Binding to a C3a product of the complement cascade.
complement component C3a binding
Binding to a C3b product of the complement cascade.
complement component C3b binding
Binding to a iC3b product of the complement cascade.
complement component iC3b binding
Binding to a C3dg product of the complement cascade.
complement component C3dg binding
Binding to a C3d product of the complement cascade.
complement component C3d binding
Binding to a C4b product of the classical complement cascade.
complement component C4b binding
Binding to a C5a product of the complement cascade.
complement component C5a binding
Combining with the C1q complex, a component of the classical complement cascade, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
complement component C1q receptor activity
Combining with the iC3b product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
complement component iC3b receptor activity
Combining with the C3dg product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
complement component C3dg receptor activity
Combining with the C3d product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
complement component C3d receptor activity
Combining with the C4b product of the classical complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
complement component C4b receptor activity
Binding to a collectin, a member of a group of structurally related pattern recognition molecules characterized by having a carbohydrate recognition domain of the C-type lectin family at the C-terminus and a collagenous domain at the N-terminus.
collectin binding
Combining with a collectin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
collectin receptor activity
Binding to a pentraxin, a member of a family of inflammatory proteins with a radially symmetric arrangement of five identical, noncovalently linked chains in a pentagonal array.
pentraxin binding
The series of events in which a stimulus from a yeast is received and converted into a molecular signal.
detection of yeast
The process in which the Mullerian ducts, primordia of the oviducts, uterus and upper vagina, undergo regression in male embryos.
Mullerian duct regression
The change in form (cell shape and size) that occurs during the differentiation of an endothelial cell.
endothelial cell morphogenesis
A programmed cell death process observed in bacteria and filamentous fungi and leading to spontaneous death by lysis. Examples are lysis of the mother cell during sporulation of Bacillus subtilis and self-degradation of fungal cells in Aspergillus nidulans. Autolysis is also involved in bacterial biofilm formation.
autolysis
Binding to a farnesylated protein.
farnesylated protein binding
The pronucleus originating from the ovum that is being fertilized.
female pronucleus
The pronucleus originating from the spermatozoa that was involved in fertilization.
male pronucleus
A developmental process, independent of morphogenetic (shape) change, that is required for a blood vessel to attain its fully functional state.
blood vessel maturation
Replacement ossification wherein bone tissue replaces cartilage.
endochondral ossification
Binding to a fibronectin, a group of related adhesive glycoproteins of high molecular weight found on the surface of animal cells, connective tissue matrices, and in extracellular fluids.
fibronectin binding
Binding to retinoic acid, 3,7-dimethyl-9-(2,6,-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid.
retinoic acid binding
A process that is triggered by vasomotor excitation and results in a decrease in the diameter of an artery during the baroreceptor response to decreased blood pressure.
vasoconstriction of artery involved in baroreceptor response to lowering of systemic arterial blood pressure
The process in which the juxtaglomerular cells of the kidneys receive information about the amount of blood flowing through the arterioles and converts the information to a molecular signal.
detection of renal blood flow
The process by a carbon dioxide stimulus is received and converted to a molecular signal by the vasomotor center of the central nervous system.
detection of carbon dioxide by vasomotor center
The vasoconstriction that is triggered by vasomotor excitation resulting from the detection of high carbon dioxide levels in the vasomotor center of the central nervous system.
vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure
The neurological process in which the brain senses excessive caloric intake.
detection of dietary excess
An eating behavior process whereby detection of a dietary excess results in a decrease in intake of nutrients.
reduction of food intake in response to dietary excess
The process that results in increased metabolic rate in tissues of an organism. It is triggered by the detection of dietary excess. This process is achieved via signaling in the sympathetic nervous system.
diet induced thermogenesis
Binding to one of the p53 family of proteins.
p53 binding
The orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels during intussusceptive angiogenesis.
blood vessel endothelial cell migration involved in intussusceptive angiogenesis
The process that modulates the frequency, rate or extent of attachment of a blood vessel endothelial cell to another cell or to the extracellular matrix involved in intussusceptive angiogenesis.
regulation of cell adhesion involved in intussusceptive angiogenesis
The chemical reactions and pathways resulting in the formation of the siderochrome pyoverdine.
pyoverdine biosynthetic process
The chemical reactions and pathways resulting in the breakdown of the siderochrome pyoverdine.
pyoverdine catabolic process
The commitment of mesenchymal cells to the specific cell fate of an osteoblast. An osteoblast is a bone-forming cell which secretes an extracellular matrix. Hydroxyapatite crystals are then deposited into the matrix to form bone.
osteoblast fate commitment
Binding to cytosine.
cytosine binding
Binding to guanine.
guanine binding
Binding to uracil.
uracil binding
Binding to thymine.
thymine binding
The process whose specific outcome is the progression of an osteoblast over time, from its formation to the mature structure. Osteoblast development does not include the steps involved in committing a cranial neural crest cell or an osteoprogenitor cell to an osteoblast fate. An osteoblast is a cell that gives rise to bone.
osteoblast development
The proteolytic digestion of components in the acrosomal matrix that occurs as part of the acrosome reaction. The process can occur either in the cumulus oophorous facilitating the penetration of it by the sperm, or at the zona pellucida allowing the sperm to reach the plasma membrane of the egg where the inner acrosomal membrane of the sperm can interact with the egg plasma membrane.
acrosome matrix dispersal
The acrosomal membrane region that underlies the acrosomal vesicle and is located toward the sperm nucleus. This region is responsible for molecular interactions allowing the sperm to penetrate the zona pellucida and fuses with the egg plasma membrane.
inner acrosomal membrane
The acrosomal membrane region that underlies the plasma membrane of the sperm. This membrane fuses with the sperm plasma membrane as part of the acrosome reaction.
outer acrosomal membrane
The removal of palymitoyl groups from a lipoprotein.
protein depalmitoylation
A process in which force is generated within involuntary skeletal muscle tissue, resulting in a change in muscle geometry. This process occurs in the diaphragm. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The diaphragm is a striated muscle that is necessary for the process of respiratory gaseous exchange.
diaphragm contraction
A punctate, filamentous structure composed of Bcl10 that appears in the cytoplasm of T-cells shortly after T-cell receptor stimulation. Polkadots stands for Punctate Oligomeric Killing and Activating DOmains Transducing Signals.
polkadots
The process in which a guanine in t position 34 of a tRNA is post-transcriptionally modified.
tRNA wobble guanine modification
The process in which an adenosine in position 34 of a tRNA is post-transcriptionally converted to inosine.
tRNA wobble adenosine to inosine editing
Endonucleolytic cleavage between the 5S rRNA and the 4.5S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript.
endonucleolytic cleaveage between 4.5S rRNA and 5S rRNA of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)
Endonucleolytic cleavage between the LSU-rRNA and the 4.5S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript.
endonucleolytic cleaveage between LSU-rRNA and 4.5S rRNA of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)
Endonucleolytic cleavages between the SSU-rRNA and the LSU-rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. These cleavages liberate tRNAs from the polycistronic transcript as well as separating the SSU and LSU containing transcript. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript.
endonucleolytic cleaveage between SSU-rRNA and LSU-rRNA of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)
The removal of extra uridine residues from the 3' end of a 5S pre-rRNA generated by transcription by RNA polymerase III to generate the mature 3'-end.
generation of mature 3'-end of 5S rRNA generated by RNA polymerase III
The insertion of one or two non-coded nucleotides during the transcription of a mitochondrial rRNA. Such additions are known to occur in myxomycetes such as Physarum, Didymium, and Stemonitis.
cotranscriptional mitochondrial rRNA nucleotide insertion
A heterodimeric complex of BRCA2 and BRAF35 (BRCA2-associated factor 35). The BRCA2-BRAF35 complex is often associated with condensed chromatin during mitosis.
BRCA2-BRAF35 complex
The process whose specific outcome is the progression of the amphibian larva over time, from its formation to the mature structure. Amphibian larvae, sometimes called pollywogs or tadpoles, hatch from eggs and begin to grow limbs and other adult physical features at various times, depending on the species, before they metamorphose into the adult form.
amphibian larval development
The process in which the ribose of guanosine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'-O position.
wobble position guanine ribose methylation
The process in which the ribose of cytidine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'-O position.
wobble position cytosine ribose methylation
The process in which the ribose of uridine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'-O position.
wobble position uridine ribose methylation
A stable heterodimeric complex composed of polycystin-1 and polycystin-2.
polycystin complex
Binding to UTP, uridine 5'-triphosphate.
UTP binding
Binding to CTP, cytidine 5'-triphosphate.
CTP binding
The process in which the carbonyl of cytosine at position 34 of a tRNA is post-transcriptionally replaced by lysine.
tRNA wobble base lysidine biosynthesis
A complex of proteins that connect growing stereocilia in developing cochlear hair cells, composed of Vlgr1, usherin, vezatin, and whirlin.
stereocilia ankle link complex
The process in which bile acids are covalently linked to taurine or glycine.
bile acid conjugation
A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a desmosome. A desmosome is a patch-like intercellular junction found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an space of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm.
desmosome assembly
The maintenance of a desmosome. A desmosome is a patch-like intercellular junctions found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an interspace of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm.
desmosome maintenance