nucleoside analogue (CHEBI:60783)
Definition: An analogue of a nucleoside, being an N-glycosyl compound in which the nitrogen-containing moiety is a modified nucleotide base. They are commonly used as antiviral products to prevent viral replication in infected cells.
Example SMILES structures:
[C@@H]1(N2C(NC(=O)C(=C2)C(=O)O)=O)O[C@H](CO)[C@H](C1)O
N(C=1N=CN=C2C1N=CN2[C@@H]3O[C@H](CO)[C@@H](O)C3)CC(=O)N
C12C(C3C1N(C(N=C3N)=O)[C@@H]4O[C@@H]([C@H](C4)O)CO)C(=NC(N2[C@@H]5O[C@@H]([C@H](C5)O)CO)=O)N
C12C(C3(C1N(C(NC3=O)=O)[C@@H]4O[C@@H]([C@H](C4)O)CO)C)C(=NC(N2[C@@H]5O[C@@H]([C@H](C5)O)CO)=O)N
[C@@H]1(N2C(NC(=O)C(=N2)C)=O)O[C@H](CO)[C@H](C1)O
C12N(C(NC(C1(C)C3(C2N(C(NC3=O)=O)[C@@H]4O[C@@H]([C@H](C4)O)CO)C)=O)=O)[C@@H]5O[C@@H]([C@H](C5)O)CO
C1(C(C(=NC(N1[C@@H]2O[C@H](CO)[C@H](C2)O)=O)N)O)O
[C@H]1(O[C@@H]([C@H]([C@@H]1O)O)CO)N2C=NC(=NC2=O)N
[C@@H]1([C@@H]([C@H](O)[C@H](O1)CO)O)N2C=3N=CN=C(C3C(=C2)C(=O)O)N
O1[C@@H]([C@H]([C@@H]([C@@H]1N2C(N=C(C=C2)NC(CCCCCCCCCCCCCCC)=O)=O)C#N)O)CO
C[C@@H]1C[C@H]1\C=C\[C@@H]1C[C@H]1[C@@H]1C[C@H]1[C@@H]1C[C@H]1[C@@H]1C[C@H]1\C=C\C=C\C(=O)NC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1CCC(=O)NC1=O
NC1=C2N=CN([C@H]3C[C@H](O)[C@@H](COP(O)(=O)O[C@H]4C[C@@H](O[C@@H]4CO)N4C=NC5=C(N)N=CN=C45)O3)C2=NC=N1
NC1=NC(=O)N(C=C1)[C@H]1C[C@H](O)[C@@H](COP(O)(=O)O[C@H]2C[C@@H](O[C@@H]2CO)N2C=NC3=C(N)N=CN=C23)O1
NC1=NC2=C(N=CN2[C@H]2C[C@H](O)[C@@H](COP(O)(=O)O[C@H]3C[C@@H](O[C@@H]3CO)N3C=NC4=C(N)N=CN=C34)O2)C(=O)N1
CC1=CN([C@H]2C[C@H](O)[C@@H](COP(O)(=O)O[C@H]3C[C@@H](O[C@@H]3CO)N3C=NC4=C(N)N=CN=C34)O2)C(=O)NC1=O
NC1=NC(=O)N(C=C1)[C@H]1C[C@H](OP(O)(=O)OC[C@H]2O[C@H](C[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](CO)O1
NC1=NC2=C(N=CN2[C@H]2C[C@H](OP(O)(=O)OC[C@H]3O[C@H](C[C@@H]3O)N3C=NC4=C(N)N=CN=C34)[C@@H](CO)O2)C(=O)N1
NC1=NC2=C(N=CN2[C@H]2C[C@H](OP(O)(=O)OC[C@H]3O[C@H](C[C@@H]3O)N3C=CC(N)=NC3=O)[C@@H](CO)O2)C(=O)N1
NC1=NC2=C(N=CN2[C@H]2C[C@H](O)[C@@H](COP(O)(=O)O[C@H]3C[C@@H](O[C@@H]3CO)N3C=NC4=C3N=C(N)NC4=O)O2)C(=O)N1
CC1=CN([C@H]2C[C@H](O)[C@@H](COP(O)(=O)O[C@H]3C[C@@H](O[C@@H]3CO)N3C=NC4=C3N=C(N)NC4=O)O2)C(=O)NC1=O
CC1=CN([C@H]2C[C@H](OP(O)(=O)OC[C@H]3O[C@H](C[C@@H]3O)N3C=NC4=C(N)N=CN=C34)[C@@H](CO)O2)C(=O)NC1=O
CC1=CN([C@H]2C[C@H](OP(O)(=O)OC[C@H]3O[C@H](C[C@@H]3O)N3C=NC4=C3N=C(N)NC4=O)[C@@H](CO)O2)C(=O)NC1=O
NC1=C2N=CN([C@@H]3O[C@H](CO)[C@@H](OP(O)(=O)OC[C@H]4O[C@H]([C@H](O)[C@@H]4O)N4C=CC(=O)NC4=O)[C@H]3O)C2=NC=N1
NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](CO)[C@@H](OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@H]1O
NC1=NC2=C(N=CN2[C@@H]2O[C@H](CO)[C@@H](OP(O)(=O)OC[C@H]3O[C@H]([C@H](O)[C@@H]3O)N3C=NC4=C(N)N=CN=C34)[C@H]2O)C(=O)N1
NC1=NC2=C(N=CN2[C@@H]2O[C@H](COP(O)(=O)O[C@@H]3[C@@H](CO)O[C@H]([C@@H]3O)N3C=NC4=C3N=C(N)NC4=O)[C@@H](O)[C@H]2O)C(=O)N1
NC1=NC2=C(N=CN2[C@@H]2O[C@H](CO)[C@@H](OP(O)(=O)OC[C@H]3O[C@H]([C@H](O)[C@@H]3O)N3C=CC(=O)NC3=O)[C@H]2O)C(=O)N1
NC1=C2N=CN([C@@H]3O[C@H](COP(O)(=O)O[C@@H]4[C@@H](CO)O[C@H]([C@@H]4O)N4C=CC(=O)NC4=O)[C@@H](O)[C@H]3O)C2=NC=N1
NC1=NC2=C(N=CN2[C@@H]2O[C@H](COP(O)(=O)O[C@@H]3[C@@H](CO)O[C@H]([C@@H]3O)N3C=CC(=O)NC3=O)[C@@H](O)[C@H]2O)C(=O)N1
NC(=O)C1=NC(F)=CN([C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)C1=O
CC(C)C(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=CC(NC1=O)=NO
OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=CC(NC1=O)=NO
OC1C(N2C3=NC=NC(N)=C3N=C2)C=C(C1O)CO
Nc1ncn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=S)[nH]c1=O
O[C@@H]1[C@H](O)[C@@H](CO)C[C@H]1N2C3=NC=NC(=C3N=C2)N
O[C@@H]1C(=C[C@H]([C@@H]1O)N2C3=NC=NC(=C3N=C2)N)CO
NC1=NC(=O)N(C=C1C#C)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
NC(=O)c1ncn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c1N
Nc1nc(=O)n(cc1F)[C@@H]1CS[C@H](CO)O1
[H][C@]12OC[C@](CO)(O[C@H]1n1cc(C)c(N)nc1=O)[C@H]2O
COC(=O)N[C@@H](CCc1c(C)nc2n(C)c3n(cnc3c(=O)n12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O)C(=O)OC
Nc1nc(=O)[nH]cc1F
OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=S
OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
CSc1nc(NCC=C(C)C)c2ncn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c2n1
CSc1nc(NC\C=C(\C)CO)c2ncn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c2n1
CC(C)=CCNc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
Nc1ccn([C@@H]2CS[C@H](CO)O2)c(=O)n1
Cc1cn([C@@H]2O[C@H](CO)C=C2)c(=O)[nH]c1=O
Nc1nc(F)nc2n(cnc12)[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@@H]1O
C[C@H](Cn1cnc2c(N)ncnc12)OCP(O)(O)=O
Cc1cn2c(nc3n(cnc3c2=O)[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)[nH]1
COC(=O)N[C@@H](C(Cc1c(C)nc2n(C)c3n(cnc3c(=O)n12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O)OO)C(=O)OC
Cn1nc(N)c2cn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c3ncnc1c23
C\C(CO)=C/CNc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
CC(C)=CCNc1nc(S)nc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
NCc1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=S)[nH]c1=O
OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ncc2c1[nH]cnc2=O
OC[C@H]1O[C@H](C[C@@H]1O)n1cc(c(=O)[nH]c1=O)C(F)(F)F
NC(=O)CNc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
NC(=O)c1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c2ncnc(N)c12
Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@H]1CO
C12=C(N=CN1C3OCCC3)C(=NC=N2)N
C1CC1NC2=NC(=NC3=C2N=CN3[C@@H]4C[C@@H](C=C4)CO)N.C1CC1NC2=NC(=NC3=C2N=CN3[C@@H]4C[C@@H](C=C4)CO)N