Zibalwa kakhulu iimeko esethe zabonwa ezinokudala okokuba umntu abekumngcipheko we-choanal atresia. Nangona unobangela wesi sifo ungekaziwa, ufuzo neemeko zendalo ziyakrokrelwa. Esinye isifundo sibonisa okokuba iikhemikhali ezisebenza njenge-endocrine interrupters zingayibeka emngciphekweni imveku engekazalwa. Isifundo se-epidemiological sango-2012 saqwalasela kwi-atrazine, i-herbicide exhaphakileyo kwelase-U.S., kwafunyaniswa okokuba abafazi abahlala kwiingingqi zolwawulo lwase Texas ezinale khemikhali ekwizinga eliphezulu nesetyenziselwa ukuncothula ukhula, kwaafunyaniswa okokuba aba malunga nama- 80 amathuba okuzala iintsana ezinale choanal atresia okanye i-stenosis xa kuthelekiswa nabafazi abahlala kwiingingqi zolwawulo apho liphantsi izinga lale khemikhali. Enye ingxelo ye-epidemiological yango-2010 yafumanisa unxulumano olungaphezulu phakathi kokwanda kwezi meko ze-choanal atresia kwanokuvelela kwisandla sokutshaya, ekuphungeni ifofu, nakubantu abaphila ngokuthatha i-maternal zinc ne-B-12 kwanokuvelela kumayeza a-anti-infective urinary tract.