Ezekwesili started off in the Olusegun Obasanjo administration as the Pioneer head of the Budget Monitoring and Price Intelligence Unit (aka Due Process Unit). It was in this position that she earned the sobriquet of ""Madam Due Process"" for the outstanding work she led a team of professionals to do in sanitising public procurement or contracting at the Federal level in Nigeria. She was the architect of the Bureau for Public Procurement legislation, the NEITI legislation and the new Minerals and Mining legislation during her six and a half years stint in government.