Virus epesamaka na nzela ya kosimba ba mayi na makila ya nzoto, neti makila, ya mutu to ya banyama oyo baza infecté. Yango ekoki mpe kosalema na nzela ya kosimba eloko eye ewuti kozala contaminé na ba mayi to makila ya nzoto. Bopalanganisi bua bokono na mopepe kati na ba primate, bakisa mpe batu, naino esembolami te ezala na ba laboratoire to libanda Makidi to miliki ya libele ya mutu sima na libiki naye na Ebola ekoki kokoba kozala na virus kino mua baposo to ba sanza. Endimami ete ba ngembo nde baza normal bakumbi na mokili, bakoki kobola virus mpe komona mpasi nayango te. Makono masusu neti malaria, cholera, fièvre typhoide, méningite mpe ba fiévre hémoragique viral makoki komonana neti Ebola. Basalaka teste ya ba échantillion ya makila mpo na RNA viral, ba anticorps to mpo na virus yango moko mpo na koconfirmer diagnostic.