Ihe mbu eji testosteronụ eme bụ iji ya agwo ụmụ nwoke nwere obele ma ọ bụ enweghi ncha ncha mmepụta eke (natural) testosteronụ, nke a kpọrọ 'hypogonadism', ma ọ bụ 'hypoandrogenism' (ụkọ androgen). Ogwugwo ọrịa a ka ana akpọ, 'Hormone Replacement Therapy (HRT)', ma ọ bụ, maka ido anya, 'Testosterone Replacement Therapy (HRT)' ma ọ bụ 'Androgen Replacement Therapy (ART)'. E ji ya eme ka larịị ọbara testosteronụ n' nwoke arụ zuru oke nke ọma nọgide na-enwe.