LLukas22/scidocs huggingface dataset:
Generator replacement is associated with an increased rate of ICD lead alerts.

BACKGROUND
Lead malfunction is an important cause of morbidity and mortality in patients with an implantable cardioverter-defibrillator (ICD). We have shown that the failure of recalled high-voltage leads significantly increases after ICD generator replacement. However, generator replacement has not been recognized as a predictor of lead failure in general.


OBJECTIVE
The purpose of this study is to assess the effect of ICD generator exchange on the rate of ICD lead alerts.


METHODS
A time-dependent Cox proportional hazards model was used to analyze a database of remotely monitored ICDs. The model assessed the impact of generator exchange on the rate of lead alerts after ICD generator replacement.


RESULTS
The analysis included 60,219 patients followed for 37 ± 19 months. The 5-year lead survival was 99.3% (95% confidence interval 99.2%-99.4%). Of 60,219 patients, 7458 patients (12.9%) underwent ICD generator exchange without lead replacement. After generator replacement, the rate of lead alerts was more than 5-fold higher than in controls with leads of the same age without generator replacement (hazard ratio 5.19; 95% confidence interval 3.45-7.84). A large number of lead alerted within 3 months of generator replacement. Lead alerts were more common in patients with single- vs dual-chamber ICDs and in younger patients. Sex was not associated with lead alerts.


CONCLUSION
Routine generator replacement is associated with a 5-fold higher risk of lead alert compared to age-matched leads without generator replacement. This suggests the need for intense surveillance after generator replacement and the development of techniques to minimize the risk of lead damage during generator replacement.
Histamine intolerance and dietary management: A complete review.

BACKGROUND
Present in several types of food, bioactive amines are described as organic bases of low molecular weight, which constitute a potential health risk. An awareness of amine levels in foods today is therefore important in relation to food safety and patient care. This review aims to emphasise the need to unify the information on the content of biogenic amines in foods and prevent patients' misunderstanding.


METHODS
Selective literature search for relevant publications in PubMed and other scientific data bases combined with further data from the World Wide Web on histamine and other amines content in foods.


RESULTS
Available reference sources do not reflect a homogeneous consensus, and the variation between foods makes it impossible for dieticians to accurately estimate amines content to correctly advise patients.


CONCLUSIONS
To achieve the goal of collecting reliable information, all methods and tools used in analytical studies should be standardised and information exposed to patients should be verified.
The influence of persuasion, training and experience on user perceptions and acceptance of IT innovation

Information technology (IT) cannot produce any positive outcome unless it is adopted and used. Theories and empirical research suggest that IT adoption and usage are determined by user beliefs and attitudes toward IT. However, little is known about what factors affect the formation and change over time of user beliefs and attitudes. It is critical to understand such factors so that effective managerial interventions can be created and implemented to positively influence user acceptance and use of IT innovations. Based on theories of innovation diffusion, information technology adoption, and persuasion, this study investigates the effect of persuasion, training, and direct-use experience on the formation and change over time of user perceptions and adoption decisions of IT innovation. The results of a longitudinal experimental study show that persuasion significantly affects the formation of users’ initial perceptions, attitude toward, and intention to adopt IT. Training provided in the introduction stage of IT innovation helps the user form a more realistic expectation. As users’ direct-use experience with IT innovation increases over time, their perceptions and adoption intentions change substantially. The results suggest that persuasion, training, and direct-use experience are important variables that need to be considered in IT innovation and adoption research and
Whether or not to engage in sexting: Explaining adolescent sexting behaviour by applying the prototype willingness model

Sexting has received increasing scholarly and media attention. Especially, minors’ engagement in this behaviour is a source of concern. As adolescents are highly sensitive about their image among peers and prone to peer influence, the present study implemented the prototype willingness model in order to assess how perceptions of peers engaging in sexting possibly influence adolescents’ willingness to send sexting messages. A survey was conducted among 217 15to 19-year-olds. A total of 18% of respondents had engaged in sexting in the 2 months preceding the study. Analyses further revealed that the subjective norm was the strongest predictor of sexting intention, followed by behavioural willingness and attitude towards sexting. Additionally, the more favourable young people evaluated the prototype of a person engaging in sexting and the higher they assessed their similarity with this prototype, the more they were willing to send sexting messages. Differences were also found based on gender, relationship status and need for popularity. 2015 Elsevier Ltd. All rights reserved.
Estrogen receptor in pelvic floor tissues in patients with stress urinary incontinence

Our study is to investigate the presence of estrogen receptor (ER) and its possible etiological relationship with the development of stress urinary incontinence (SUI). Thirty-one biopsy specimens from pelvic floor tissues were obtained from 31 patients categorized into three groups: pelvic organ prolapse (POP), SUI and control groups. ER in the pelvic muscles tissues was evaluated quantitatively after immunohistochemical staining to visualize the ER in the tissue. The sampling rate of levator ani (striated) muscle was 6.7% in total sample from the pelvic floor tissues, with the remaining showing connective tissues, smooth muscles and nerve fibers. ER positive staining was found in the in the nuclei of connective tissue, smooth muscles and nerve fibers. The positive rates of ER staining in tissues were 1.4%, 4.7% and 5.7%, respectively in control group versus 1.1%, 2.8% and 2.7% in SUI group and 4.1%, 9.5% and 11.6% in POP group. The positive rates of ER staining in connective tissue, smooth muscle and nerve fibers in SUI group were significantly lower than that in control and POP group (P<0.01). Our study suggests that a decrease of ER in the pelvic floor tissues might be related to the occurrence of SUI and implies that hormone replacement therapy might not be effective in treatment for SUI.
Treatment of high-risk Philadelphia chromosome-negative acute lymphoblastic leukemia in adolescents and adults according to early cytologic response and minimal residual disease after consolidation assessed by flow cytometry: final results of the PETHEMA ALL-AR-03 trial.

PURPOSE
Minimal residual disease (MRD) is an important prognostic factor in adults with acute lymphoblastic leukemia (ALL) and may be used for treatment decisions. The Programa Español de Tratamientos en Hematología (PETHEMA) ALL-AR-03 trial (Treatment of High Risk Adult Acute Lymphoblastic Leukemia [LAL-AR/2003]) assigned adolescent and adult patients (age 15 to 60 years) with high-risk ALL (HR-ALL) without the Philadelphia (Ph) chromosome to chemotherapy or to allogeneic hematopoietic stem-cell transplantation (allo-HSCT) according to early cytologic response (day 14) and flow-MRD level after consolidation.


PATIENTS AND METHODS
Patients with good early cytologic response (< 10% blasts in bone marrow at day 14 of induction) and a flow-MRD level less than 5 × 10(-4) at the end of consolidation were assigned to delayed consolidation and maintenance therapy, and allo-HSCT was scheduled in patients with poor early cytologic response or flow-MRD level ≥ 5 × 10(-4).


RESULTS
Complete remission was attained in 282 (87%) of 326 patients, and 179 (76%) of 236 patients who completed early consolidation were assigned by intention-to treat to receive allo-HSCT (71) or chemotherapy (108). Five-year disease-free survival (DFS) and overall survival (OS) probabilities were 37% and 35% for the whole series, 32% and 37% for patients assigned to allo-HSCT, and 55% and 59% for those assigned to chemotherapy. Multivariable analysis showed poor MRD clearance (≥ 1 × 10(-3) after induction and ≥ 5 × 10(-4) after early consolidation) as the only prognostic factor for DFS and OS.


CONCLUSION
Prognosis for Ph-negative HR-ALL in adolescents and adults with good early response to induction and low flow-MRD levels after consolidation is quite favorable when allo-HSCT is avoided. In this study, the pattern of MRD clearance was the only prognostic factor for DFS and OS.
Sleep Quality and Psychological Adjustment in Chronic Fatigue Syndrome

Without specific etiology or effective treatment, chronic fatigue syndrome (CFS) remains a contentious diagnosis. Individuals with CFS complain of fatigue and poor sleep—symptoms that are often attributed to psychological disturbance. To assess the nature and prevalence of sleep disturbance in CFS and to investigate the widely presumed presence of psychological maladjustment we examined sleep quality, sleep disorders, physical health, daytime sleepiness, fatigue, and psychological adjustment in three samples: individuals with CFS; a healthy control group; and individuals with a definite medical diagnosis: narcolepsy. Outcome measures included physiological evaluation (polysomnography), medical diagnosis, structured interview, and self-report measures. Results indicate that the CFS sample had a very high incidence (58%) of previously undiagnosed primary sleep disorder such as sleep apnea/hypopnea syndrome and restless legs/periodic limb movement disorder. They also had very high rates of self-reported insomnia and nonrestorative sleep. Narcolepsy and CFS participants were very similar on psychological adjustment: both these groups had more psychological maladjustment than did control group participants. Our data suggest that primary sleep disorders in individuals with CFS are underdiagnosed in primary care settings and that the psychological disturbances seen in CFS may well be the result of living with a chronic illness that is poorly recognized or understood.
Monitoring and modelling of urban sprawl using remote sensing and GIS techniques

The concentration of people in densely populated urban areas, especially in developing countries, calls for the use of monitoring systems like remote sensing. Such systems along with spatial analysis techniques like digital image processing and geographical information system (GIS) can be used for the monitoring and planning purposes as these enable the reporting of overall sprawl at a detailed level. In the present work, urban sprawl of the Ajmer city (situated in Rajasthan State of India) has been studied at a mid scale level, over a period of 25 years (1977–2002), to extract the information related to sprawl, area of impervious surfaces and their spatial and temporal variability. Statistical classification approaches have been used for the classification of the remotely sensed images obtained from various sensors viz. Landsat MSS, TM, ETM+ and IRS LISS-III. Urban sprawl and its spatial and temporal characteristics have been derived from the classified satellite images. The Shannon’s entropy and landscape metrics (patchiness and map density) have been computed in terms of spatial phenomenon, in order to quantify the urban form (impervious area). Further, multivariate statistical techniques have been used to establish the relationship between the urban sprawl and its causative factors. Results reveal that land development (160.8%) in Ajmer is more than three times the population growth (50.1%). Shannon’s entropy and landscape metrics has revealed the spatial distribution of the urban sprawl over a period of last 25 years. # 2007 Published by Elsevier B.V. www.elsevier.com/locate/jag International Journal of Applied Earth Observation and Geoinformation 10 (2008) 26–43
Structural equation model testing the situation-specific theory of heart failure self-care.

AIM
To test the situation-specific theory of heart failure self-care with structural equation modelling.


BACKGROUND
Several authors have proposed theories on heart failure self-care, but only the situation-specific theory of heart failure self-care by Riegel and Dickson is focused on the process that patients use to perform self-care. This theory has never been tested with structural equation modelling.


DESIGN
A secondary analysis of data from a cross-sectional study.


METHODS
Patients with heart failure were recruited in 21 cardiovascular centres across Italy during 2011. Data were collected with a sociodemographic questionnaire, chart abstraction for clinical data and the Self-Care of Heart Failure Index v.6.2.


RESULTS
A sample of 417 participants was enrolled in the study (59% males, mean age 72 years). The following propositions were tested and supported: Symptom monitoring correlates with treatment adherence; symptom monitoring and treatment adherence have a direct, positive relationship with symptom recognition and evaluation that in turn have a direct, positive relationship with treatment implementation; treatment implementation has a direct, positive relationship with treatment evaluation. In addition, the following three relationships were found: Symptom monitoring has a direct, positive relationship with treatment implementation; symptom recognition and evaluation have direct, positive relationships with treatment evaluation and symptom monitoring correlates with treatment evaluation. [Correction added on 9th April 2013, after first online publication: '…symptom monitoring correlates with treatment implementation.' has been corrected to read '…symptom monitoring correlates with treatment evaluation.']


CONCLUSION
The data support the situation-specific theory of heart failure self-care with the addition of three new relationships that emerged from the analysis. Results of this study lend further support to the use of the situation-specific theory of heart failure self-care in research and practice.
Pretreatment frontal EEG and changes in suicidal ideation during SSRI treatment in major depressive disorder.

OBJECTIVE
We investigated frontal quantitative EEG (QEEG) as predictor of changes in suicidal ideation (SI) during SSRI treatment in major depressive disorder (MDD).


METHOD
Eighty-two subjects meeting DSM-IV criteria for MDD entered an 8-week, prospective, open-label treatment with flexible dose SSRIs and completed at least 4 weeks of treatment. We assessed MDD severity with the 17-item Hamilton Depression Rating Scale (HAM-D-17); change in SI was measured with HAM-D item no. 3. We recorded four-channel EEGs (F7-Fpz, F8-Fpz, A1-Fpz, A2-Fpz) before treatment.


RESULTS
During the first 4 weeks of treatment 9 (11%) subjects experienced worsening SI. Left-right asymmetry of combined theta + alpha power correlated significantly with change in SI from baseline, even when adjusting for changes in depression severity (HAM-D-17) and for the SSRI utilized.


CONCLUSION
Frontal QEEG parameters before treatment may predict worsening SI during SSRI treatment in MDD.
Effect of pain reduction on postural sway, proprioception, and quadriceps strength in subjects with knee osteoarthritis.

OBJECTIVE
To investigate whether alleviation of knee pain influences quadriceps function, proprioceptive acuity, and postural stability in patients with knee osteoarthritis (OA).


METHODS
A crossover, within-subject, double blind study design involving 68 subjects with painful knee OA. Each subject received an intra-articular injection into one or both knees (both if symptomatic) of either 5 ml 0.5% bupivacaine or 5 ml 0.9% saline. Two weeks later they received an injection of the alternative agent. Subjects and observer were unaware of the order of injection, which was randomly assigned. Knee pain (100 mm visual analogue scale), static postural sway, knee proprioceptive acuity, maximum voluntary contraction (MVC), and percentage activation of the quadriceps were assessed immediately before and one hour after each injection.


RESULTS
Significant pain reduction was achieved one hour post-bupivacaine (mean difference as a percentage change 56.85, 95% CI 31.01 to 73.65; p<0.001) and post-saline (mean difference as a percentage change 41.94, 95% CI 11.57 to 76.66; p< 0.001), with no significant difference between the two. Both MVC and activation increased significantly post-bupivacaine (mean percentage differences 18.83, 95% CI -31.79 to -0.26, and -11.90, 95% CI -39.53 to 2.97, respectively; both p<0.001) and post-saline (mean percentage differences -7.64, 95% CI -21.96 to 4.73, and -10.71, 95% CI -25.19 to 2.60 respectively; both p<0.001). Proprioception worsened after bupivacaine (mean percentage difference -28.15%, 95% CI -83.47 to 19.74; p=0.009), but there was no effect on postural sway; saline injection had no effects. There was no order effect, and comparison of median percentage changes showed no significant differences between injections for change in MVC, activation, proprioception, or sway.


CONCLUSION
Reduction in knee pain through either peripheral (local anaesthetic) or central (placebo) mechanisms resulted in increased MVC. This increase, however, did not result in improvements in proprioception or static postural stability, suggesting that other mechanisms play a part in these functions, at least in this acute model.
Content Based Image Retrieval: Survey

The requirement for development of CBIR is enhanced due to tremendous growth in volume of images as well as the widespread application in multiple fields. Texture, color, shape and spatial layout are the underlying traits to represent and index the images. These peculiar features of images are extracted and implemented for a similarity check among images. The problem of content based image retrieval is based on generation of peculiar query. For relevant images that meet their information need, an automated search is initiated by drawing a sketch or with the submission of image having similar features. Similarity between extracted features can be measured by using different algorithms. The use of relevance feedback as a post retrieval step enhances the optimization of the process. The necessity to explore the ever growing volume of image and video is motivating the development of efficient CBIR algorithms. Different algorithms and models for the retrieval of images have been explored over the last twenty years. In this paper an analysis of visual contents of image is done with respect to features related to low level after extracting from image that are color, texture and shape. Here most popular algorithms of feature extraction and relevance feedback that try to bridge extracted low level features and features with high level semantics gap from image are discussed. A brief overview of an algorithm has been presented which is based on fuzzy logic and is used for the selection of peculiar features.
The influence of personal dispositional factors and organizational resources on workplace violence, burnout, and health outcomes in new graduate nurses: a cross-sectional study.

BACKGROUND
The alarmingly high rate of illness-related absenteeism among nurses and recent reports of workplace violence and burnout are problematic for both the current workforce shortage and the recruitment and retention of new nurses.


OBJECTIVES
To test a model derived from Leiter and Maslach's (2004) Six Areas of Worklife Model linking workplace factors (six areas of worklife, experiences of bullying and burnout) and a personal dispositional factor (psychological capital) to new graduates mental and physical health in their first year of practice.


METHODS
A cross-sectional survey design was utilized to survey 165 Ontario nurses with one year or less experience in nursing. Participants completed measures of nurses' work environment quality, psychological capital, bullying exposure, burnout, and physical and mental health. Structural equation modelling was used to test the hypothesized model.


RESULTS
The fit indices suggested a reasonably adequate fit of the data to the hypothesized model (χ2=27.75, df=12, CFI=.97, IFI=.97, RMSEA=.09), however an additional direct path from psychological capital to emotional exhaustion substantially improved the model fit (χ2=17.94, df=11, CFI=.99, IFI=.99, RMSEA=.06). Increased psychological capital positively influenced nurses' perceived person-job fit, which in turn was negatively related to bullying exposure and emotional exhaustion, and ultimately influenced their physical and mental health.


CONCLUSIONS
The findings suggest that psychological capital and perceived person-job fit are key variables in new graduate nurses' worklife, which may contribute to decreased nurses' burnout and increased physical and mental well-being. The results support an expanded conceptualization of the areas of worklife model.
Discrimination Increases Suicidal Ideation in Black Adolescents Regardless of Ethnicity and Gender

BACKGROUND
Discrimination is a common experience for Blacks across various developmental periods. Although much is known about the effect of discrimination on suicidal ideation of adults, less is known about the same association in Black youth.


AIM
We examined the association between discrimination and suicidal ideation in a national sample of Black youth. We also explored gender and ethnic differences in this association.


METHODS
We used data from the National Survey of American Life-Adolescents (NSAL-A), 2003-2004. In total, 1170 Black adolescents entered the study. This number was composed of 810 African American and 360 Caribbean Black youth (aged 13 to 17 years). Demographic and socioeconomic factors were controls, perceived discrimination was the predictor, and lifetime suicidal ideation was the outcome. Logistic regression was used to test the association between perceived discrimination and suicidal ideation in the pooled sample, as well as based on ethnicity and gender.


RESULTS
In the pooled sample of Black youth, higher perceived discrimination was associated with higher odds of suicidal ideation (Odds Ratio (OR) = 1.09; 95% Confidence Interval (CI) = 1.02-1.17). This association was significant net of age, ethnicity, gender, and socioeconomic status. We did not find interactions between perceived discrimination and ethnicity or gender on suicidal ideation. Perceived discrimination was associated with suicidal ideation in African Americans (CI = 1.09; 95% CI = 1.01-1.17) and Caribbean Blacks (CI = 1.16; 95% CI = 1.03-1.32), males (CI = 1.11; 95% CI = 1.00-1.25), and females (CI = 1.08; 95% CI = 1.00-1.16).


CONCLUSION
Discrimination jeopardizes the mental health of Black youth. In a universal pattern, discrimination is associated with suicidal ideation in Black youth. More research is needed on this topic.
The Implementation of Industry Foundation Classes in Simulation Tools for the Building Industry

Industry Foundation Classes (IFC) provide an environment of interoperability among IFC-compliant software applications in the architecture, engineering, construction, and facilities management (AEC/FM) industry. They allow building simulation software to automatically acquire building geometry and other building data from project models created with IFCcompliant CAD software. They also facilitate direct exchange of input and output data with other simulation software. This paper discusses how simulation software can be made compliant with version 1.5 of the IFC. It also describes the immediate plans for expansion of IFC and the process of definition and addition of new classes to the model.