LLukas22/scidocs huggingface dataset:
Reciprocal learning with task cards for teaching Basic Life Support (BLS): investigating effectiveness and the effect of instructor expertise on learning outcomes. A randomized controlled trial.

BACKGROUND
Basic Life Support (BLS) education in secondary schools and universities is often neglected or outsourced because teachers indicate not feeling competent to teach this content.


OBJECTIVE
Investigate reciprocal learning with task cards as instructional model for teaching BLS and the effect of instructor expertise in BLS on learning outcomes.


METHODS
There were 175 students (mean age = 18.9 years) randomized across a reciprocal/BLS instructor (RBI) group, a reciprocal/non-BLS instructor (RNI) group, and a traditional/BLS instructor group (TBI). In the RBI and RNI group, students were taught BLS through reciprocal learning with task cards. The instructor in the RBI group was certified in BLS by the European Resuscitation Council. In the TBI, students were taught BLS by a certified instructor according to the Belgian Red Cross instructional model. Student performance was assessed 1 day (intervention) and 3 weeks after intervention (retention).


RESULTS
At retention, significantly higher BLS performances were found in the RBI group (M = 78%), p = 0.007, ES = 0.25, and the RNI group (M = 80%), p < 0.001, Effect Size (ES) = .36, compared to the TBI (M = 73%). Significantly more students remembered and performed all BLS skills in the experimental groups at intervention and retention. No differences in BLS performance were found between the reciprocal groups. Ventilation volumes and flow rates were significantly better in the TBI at intervention and retention.


CONCLUSION
Reciprocal learning with task cards is a valuable model for teaching BLS when instructors are not experienced or skilled in BLS.
An intervention program with the aim to improve and maintain work productivity for workers with rheumatoid arthritis: design of a randomized controlled trial and cost-effectiveness study

BACKGROUND
Workers with rheumatoid arthritis (RA) often experience restrictions in functioning at work and participation in employment. Strategies to maintain work productivity exist, but these interventions do not involve the actual workplace. Therefore the aim of this study is to investigate the (cost)effectiveness of an intervention program at the workplace on work productivity for workers with RA.


METHODS/DESIGN
This study is a randomized controlled trial (RCT) in specialized rheumatology treatment centers in or near Amsterdam, the Netherlands. Randomisation to either the control or the intervention group is performed at patient level. Both groups will receive care as usual by the rheumatologist, and patients in the intervention group will also take part in the intervention program. The intervention program consists of two components; integrated care, including a participatory workplace intervention. Integrated care involves a clinical occupational physician, who will act as care manager, to coordinate the care. The care manager has an intermediate role between clinical and occupational care. The participatory workplace intervention will be guided by an occupational therapist, and involves problem solving by the patient and the patients' supervisor. The aim of the workplace intervention is to achieve consensus between patient and supervisor concerning feasible solutions for the obstacles for functioning at work. Data collection will take place at baseline and after 6 and 12 months by means of a questionnaire. The primary outcome measure is work productivity, measured by hours lost from work due to presenteeism. Secondary outcome measures include sick leave, quality of life, pain and fatigue. Cost-effectiveness of the intervention program will be evaluated from the societal perspective.


DISCUSSION
Usual care of primary and outpatient health services is not aimed at improving work productivity. Therefore it is desirable to develop interventions aimed at improving functioning at work. If the intervention program will be (cost)effective, substantial improvements in work productivity might be obtained among workers with RA at lower costs. Results are expected in 2015.


TRIAL REGISTRATION NUMBER
NTR2886.
Bilateral piriformis syndrome after total hip arthroplasty

We present the case of a 39-year-old man with bilateral piriformis syndrome 4 and 6 years after two cementless total hip arthroplasties, respectively. During surgical exploration, each sciatic nerve was found to be entrapped by a tense piriformis muscle and hypertrophic posterior hip capsule. The sciatic-type pain was relieved after sectioning each piriformis muscle with external neurolysis. This is the first reported case of piriformis syndrome after total hip arthroplasty.
Effectiveness of a Peer Support Programme versus Usual Care in Disease Management of Diabetes Mellitus Type 2 regarding Improvement of Metabolic Control: A Cluster-Randomised Controlled Trial

AIM
Testing the effectiveness of peer support additionally to a disease management programme (DMP) for type 2 diabetes patients.


METHODS
Unblinded cluster-randomised controlled trial (RCT) involving 49 general practices, province of Salzburg, Austria. All patients enrolled in the DMP were eligible, n = 337 participated (intervention: 148 in 19 clusters; control: 189 in 20 clusters). The peer support intervention ran over 24 months and consisted of peer supporter recruitment and training, and group meetings weekly for physical exercise and monthly for discussion of diabetes related topics.


RESULTS
At two-year follow-up, adjusted analysis revealed a nonsignificant difference in HbA1c change of 0.14% (21.97 mmol/mol) in favour of the intervention (95% CI -0.08 to 0.36%, p = 0.22). Baseline values were 7.02 ± 1.25% in the intervention and 7.08 ± 1.25 in the control group. None of the secondary outcome measures showed significant differences except for improved quality of life (EQ-5D-VAS) in controls (4.3 points on a scale of 100; 95% CI 0.08 to 8.53, p = 0.046) compared to the intervention group.


CONCLUSION
Our peer support intervention as an additional DMP component showed no significant effect on HbA1c and secondary outcome measures. Further RTCs with a longer follow-up are needed to reveal whether peer support will have clinically relevant effects.


TRIAL REGISTRATION
This trial has been registered with Current Controlled Trials Ltd. (ISRCTN10291077).
Multimodal learning for facial expression recognition

In this paper, multimodal learning for facial expression recognition (FER) is proposed. The multimodal learning method makes the first attempt to learn the joint representation by considering the texture and landmark modality of facial images, which are complementary with each other. In order to learn the representation of each modality and the correlation and interaction between different modalities, the structured regularization (SR) is employed to enforce and learn the modality-specific sparsity and density of each modality, respectively. By introducing SR, the comprehensiveness of the facial expression is fully taken into consideration, which can not only handle the subtle expression but also perform robustly to different input of facial images. With the proposed multimodal learning network, the joint representation learning from multimodal inputs will be more suitable for FER. Experimental results on the CKþ and NVIE databases demonstrate the superiority of our proposed method. & 2015 Elsevier Ltd. All rights reserved.
Liberal : Adolf A. Berle and the vision of an American era

In this, the first full-length biography of Adolf A. Berle, Jordan A. Schwarz provides a truer understanding of the vision and aspirations of early 20th-century liberalism. Two 8-page black-and-white photograph inserts.
Long-term analgesic use after low-risk surgery: a retrospective cohort study.

BACKGROUND
This study evaluated the risk of long-term analgesic use after low-risk surgery in older adults not previously prescribed analgesics.


METHODS
We conducted a retrospective cohort study using linked, population-based administrative data in Ontario, Canada, from April 1, 1997, through December 31, 2008. We identified Ontario residents 66 years and older who were dispensed an opioid within 7 days of a short-stay surgery (cataract surgery, laparoscopic cholecystectomy, transurethral resection of the prostate, or varicose vein stripping) and assessed the risk of long-term opioid use, defined as a prescription for an opioid within 60 days of the 1-year anniversary of the surgery. In a secondary analysis, we examined the risk of long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs). We used multivariate logistic regression to examine the association between postsurgical use of analgesics and long-term use.


RESULTS
Among 391,139 opioid-naive patients undergoing short-stay surgery, opioids were newly prescribed to 27,636 patients (7.1%) within 7 days of being discharged from the hospital, and opioids were prescribed to 30,145 patients (7.7%) at 1 year from surgery. An increase in the use of oxycodone was found during this time (from 5.4% within 7 days to 15.9% at 1 year). In our primary analysis, patients receiving an opioid prescription within 7 days of surgery were 44% more likely to become long-term opioid users within 1 year compared with those who received no such prescription (adjusted odds ratio, 1.44; 95% CI, 1.39-1.50). In a secondary analysis, among 383,780 NSAID-naive patients undergoing short-stay surgery, NSAIDs were prescribed to 1169 patients (0.3%) within 7 days of discharge and to 30,080 patients (7.8%) at 1 year from surgery. Patients who began taking NSAIDs within 7 days of surgery were almost 4 times more likely to become long-term NSAID users compared with patients with no such prescription (adjusted odds ratio, 3.74; 95% CI, 3.27-4.28).


CONCLUSION
Prescription of analgesics immediately after ambulatory surgery occurs frequently in older adults and is associated with long-term use.
Synthesizable Memory Arrays Based on Logic Gates for Subthreshold Operation in IoT

This paper identifies novel directions of standard-cell-based synthesizable memory design. A compact 18T-bitcell of OR-AND-Invert (OAI) and AND-OR-Invert (AOI) logic gates is presented with bit-selective write and multiplexed read accesses. It reduces the bitcell area by 11%–40% compared to the state-of-the-art clock-gating-based D-latch schemes while avoiding custom-cell design. The improved storage density comes from the tight integration on two levels–coupling the read multiplexing within each bitcell and taking advantage of structured datapath placement in bitcell arrays by using commercial CAD tools. As measured on a 40 nm SRAM of 90 kb, the OAI/AOI-gate-based synthesizable memory features 0.4 V minimum access voltage, 30 fJ minimum read energy per bit, and a leakage power of 1.4 pW per bit at 0.3 V data retention voltage. It is ideally suited for IoT-node design operating in sub- $V_{\mathrm {t}}$  for joint dynamic energy and leakage power reduction. Further, it enables fast turn-around times by IP reuse over technology nodes with minimal (re)design effort.
ON A PROBLEM OF GRAPH THEORY

Let G " be a non-directed graph having n vertices, without parallel edges and slings. Let the vertices of Gn be denoted by F 1 ,. . ., Pn. Let v(P j) denote the valency of the point P i and put (0. 1) V(G,) = max v(Pj). 1ninn Let E(G.) denote the number of edges of Gn. Let H d (n, k) denote the set of all graphs Gn for which V (G n) = k and the diameter D (Gn) of which is-d, In the present paper we shall investigate the quantity (0 .2) Thus we want to determine the minimal number N such that there exists a graph having n vertices, N edges and diameter-d and the maximum of the valencies of the vertices of the graph is equal to k. To help the understanding of the problem let us consider the following interpretation. Let be given in a country n airports ; suppose we want to plan a network of direct flights between these airports so that the maximal number of airports to which a given airport can be connected by a direct flight should be equal to k (i .e. the maximum of the capacities of the airports is prescribed), further it should be possible to fly from every airport to any other by changing the plane at most d-1 times ; what is the minimal number of flights by which such a plan can be realized? For instance, if n = 7, k = 3, d= 2 we have F2 (7, 3) = 9 and the extremal graph is shown by Fig. 1. The problem of determining Fd (n, k) has been proposed and discussed recently by two of the authors (see [1]). In § 1 we give a short summary of the results of the paper [1], while in § 2 and 3 we give some new results which go beyond those of [1]. Incidentally we solve a long-standing problem about the maximal number of edges of a graph not containing a cycle of length 4. In § 4 we mention some unsolved problems. Let us mention that our problem can be formulated also in terms of 0-1 matrices as follows : Let M=(a il) be a symmetrical n by n zero-one matrix such 2
Linear recursion formulas of generalized focus quantities and applications

Integrability of polynomial differential system for any rational resonance ratio is studied. A new linear recursion formula for computation of generalized focus quantities and certain relation between two quantities from different definitions are given. As the applications, we discuss the generalized center conditions for two cubic Kolmogorov systems which are considered for the first time.
Efficient approaches for designing reversible Binary Coded Decimal adders

Reversible logic has become one of the most promising research areas in the past few decades and has found its applications in several technologies; such as low-power CMOS, nanocomputing and optical computing. This paper presents improved and efficient reversible logic implementations for Binary Coded Decimal (BCD) adder as well as Carry Skip BCD adder. It has been shown that the modified designs outperform the existing ones in terms of number of gates, number of garbage outputs, delay, and quantum cost. In order to show the efficiency of the proposed designs, lower bounds of the reversible BCD adders in terms of gates and garbage outputs are proposed as well. & 2008 Elsevier Ltd. All rights reserved.
A randomized study of tenofovir disoproxil fumarate in treatment-experienced HIV-1 infected adolescents.

BACKGROUND
There are few data on the safety and antiviral activity of tenofovir disoproxil fumarate (TDF) in HIV-1 infected adolescents.


METHODS
A randomized, double-blinded, placebo-controlled study was conducted. Ninety adolescents (12 to <18 years) who were viremic while receiving antiretroviral treatment were randomized to receive TDF 300 mg (mean, 216.8 mg/m(2)) or placebo in combination with an optimized background regimen (OBR) for 48 weeks. The primary efficacy endpoint was time-weighted average change in plasma HIV-1 RNA from baseline at week 24


RESULTS
Eighty-seven subjects (45 TDF, 42 placebo) received the study drug. Through week 24, the median time-weighted average change in plasma HIV-1 RNA was not different between the TDF and placebo groups (-1.6 versus -1.6 log(10)copies/mL, P = 0.55). The percentages of subjects who achieved HIV-1 RNA <400 copies/mL were similar at week 24 (40.9 versus 41.5%). One fourth of subjects in the TDF and placebo groups (24.4 versus 28.6%) had at least 3 active agents in the OBR. Many subjects in both groups had baseline genotypic resistance to TDF (48.9 versus 33.3%). TDF was generally safe and well tolerated. There were no statistically significant differences in changes of renal function and bone mineral density between the 2 groups.


CONCLUSION
This study of TDF in combination with an OBR in antiretroviral-experienced adolescents did not meet its primary or secondary efficacy endpoints. The effectiveness of the OBR and baseline genotypic resistance to TDF in both groups may have confounded the efficacy findings. No clinically relevant TDF-related renal or bone toxicities were observed in this adolescent population.
Effect of transgenic GDNF expression on gentamicin-induced cochlear and vestibular toxicity

Gentamicin administration often results in cochlear and/or vestibular hair cell loss and hearing and balance impairment. It has been demonstrated that adenovirus-mediated overexpression of glial cell line-derived neurotrophic factor (GDNF) can protect cochlear hair cells against ototoxic injury. In this study, we evaluated the protective effects of adenovirus-mediated overexpression of GDNF against gentamicin ototoxicity. An adenovirus vector expressing the human GDNF gene (Ad.GDNF) was administered into the scala vestibuli as a rescue agent at the same time as gentamicin, or as a protective agent, 7 days before gentamicin administration. Animals in the Rescue group displayed hearing thresholds that were significantly better than those measured in the Gentamicin or Ad.LacZ/Gentamicin groups. In the Protection group, Ad.GDNF afforded significant preservation of utricular hair cells. The data demonstrated protection of the inner ear structure, and rescue of the inner ear structure and function against ototoxic insults. These experiments suggest that inner ear gene therapy may be developed as a clinical tool for protecting the ear against environmentally induced insults.
Modelling the cost-effectiveness and capacity impact of changes to colposcopy referral guidelines for women with mild dyskaryosis in the UK Cervical Screening Programme.

OBJECTIVE
To evaluate the capacity implications and health economic impact of new guidelines recommending referral to colposcopy after one mild result during cervical screening rather than after two consecutive mild results.


DESIGN
A mathematical model of the country's colposcopy services and the clinical pathways from smear result through to treatment is constructed. The model incorporates national questionnaire data on referral numbers and management practices, routine data and published research results.


SETTING
All English NHS colposcopy services.


POPULATION
Women aged 25 to 64 years.


METHODS
The national average workload impact of the change in referral guidelines is predicted, and the impact in differing local circumstances is evaluated within the model. A long-term health economic model examines the resulting costs and predicted change in quality-adjusted life years (QALYs).


MAIN OUTCOME MEASURES
Colposcopy workload implications for single mild dyskaryosis referral and cost per QALY analysis.


RESULTS
We found that single mild dyskaryosis referral implies, on average, a 21% increase in colposcopy workload for services not currently operating this policy. The health economic model predicted a cost per QALY gained as a result of the implementation of the new referral guidelines of around pound7,500.


CONCLUSIONS
Referral after one mild result will increase workload at colposcopy; however, it may be possible to counterbalance the additional workload by altering other clinical practice. The change to referral guidelines would be considered cost-effective in comparison with many interventions routinely available on the NHS.
Classification methods for activity recognition

Activity recognition is an important subject in different areas of research, like e-health and ubiquitous computing. In this paper we give an overview of recent work in the field of activity recognition from both body mounted sensors and ambient sensors. We discuss some of the differences among approaches and present guidelines for choosing a suitable approach under various circumstances.
FoldingNet: Point Cloud Auto-Encoder via Deep Grid Deformation

Recent deep networks that directly handle points in a point set, e.g., PointNet, have been state-of-the-art for supervised learning tasks on point clouds such as classification and segmentation. In this work, a novel end-to-end deep auto-encoder is proposed to address unsupervised learning challenges on point clouds. On the encoder side, a graph-based enhancement is enforced to promote local structures on top of PointNet. Then, a novel folding-based decoder deforms a canonical 2D grid onto the underlying 3D object surface of a point cloud, achieving low reconstruction errors even for objects with delicate structures. The proposed decoder only uses about 7% parameters of a decoder with fully-connected neural networks, yet leads to a more discriminative representation that achieves higher linear SVM classification accuracy than the benchmark. In addition, the proposed decoder structure is shown, in theory, to be a generic architecture that is able to reconstruct an arbitrary point cloud from a 2D grid. Our code is available at http://www.merl.com/research/license#FoldingNet
A Miniaturized Semantic Segmentation Method for Remote Sensing Image

In order to save the memory, we propose a miniaturization method for neural network to reduce the parameter quantity existed in remote sensing (RS) image semantic segmentation model. The compact convolution optimization method is first used for standard U-Net to reduce the weights quantity. With the purpose of decreasing model performance loss caused by miniaturization and based on the characteristics of remote sensing image, fewer down-samplings and improved cascade atrous convolution are then used to improve the performance of the miniaturized U-Net. Compared with U-Net, our proposed Micro-Net not only achieves 29.26 times model compression, but also basically maintains the performance unchanged on the public dataset. We provide a Keras and Tensorflow hybrid programming implementation for our model: https://github.com/Isnot2bad/Micro-Net
Content-boosted Matrix Factorization Techniques for Recommender Systems

Many businesses are using recommender systems for marketing outreach. Recommendation algorithms can be either based on content or driven by collaborative filtering. We study different ways to incorporate content information directly into the matrix factorization approach of collaborative filtering. These content-boosted matrix factorization algorithms not only improve recommendation accuracy, but also provide useful insights about the contents, as well as make recommendations more easily interpretable.