LLukas22/scidocs huggingface dataset:
The Effectiveness of Mindfulness-Based Therapies for ADHD: A Meta-Analytic Review.

OBJECTIVE
Mindfulness-based therapies (MBTs) have been shown to be efficacious in treating internally focused psychological disorders (e.g., depression); however, it is still unclear whether MBTs provide improved functioning and symptom relief for individuals with externalizing disorders, including ADHD. To clarify the literature on the effectiveness of MBTs in treating ADHD and to guide future research, an effect-size analysis was conducted.


METHOD
A systematic review of studies published in PsycINFO, PubMed, and Google Scholar was completed from the earliest available date until December 2014.


RESULTS
A total of 10 studies were included in the analysis of inattention and the overall effect size was d = -.66. A total of nine studies were included in the analysis of hyperactivity/impulsivity and the overall effect was calculated at d = -.53.


CONCLUSION
Results of this study highlight the possible benefits of MBTs in reducing symptoms of ADHD.
Dose-finding study of imatinib in combination with intravenous cytarabine: feasibility in newly diagnosed patients with chronic myeloid leukemia.

The HOVON cooperative study group performed a feasibility study of escalated imatinib and intravenous cytarabine in 165 patients with early chronic-phase chronic myeloid leukemia (CML). Patients received 2 cycles of intravenous cytarabine (200 mg/m(2) or 1000 mg/m(2) days 1-7) in conjunction with imatinib (200 mg, 400 mg, 600 mg, or 800 mg), according to predefined, successive dose levels. All dose levels proved feasible. Seven dose-limiting toxicities (DLTs) were observed in 302 cycles of chemotherapy, which were caused by streptococcal bacteremia in 5 cases. Intermediate-dose cytarabine (1000 mg/m(2)) prolonged time to neutrophil recovery and platelet recovery compared with a standard dose (200 mg/m(2)). High-dose imatinib (600 mg or 800 mg) extended the time to platelet recovery compared with a standard dose (400 mg). More infectious complications common toxicity criteria (CTC) grade 3 or 4 were observed after intermediate-dose cytarabine compared with a standard-dose of cytarabine. Early response data after combination therapy included a complete cytogenetic response in 48% and a major molecular response in 30% of patients, which increased to 46% major molecular responses at 1 year, including 13% complete molecular responses. We conclude that combination therapy of escalating dosages of imatinib and cytarabine is feasible. This study was registered at www.kankerbestrijding.nl as no. CKTO-2001-03.
Acute effects of remote ischemic preconditioning on cutaneous microcirculation - a controlled prospective cohort study

BACKGROUND
Therapeutic strategies aiming to reduce ischemia/reperfusion injury by conditioning tissue tolerance against ischemia appear attractive not only from a scientific perspective, but also in clinics. Although previous studies indicate that remote ischemic intermittent preconditioning (RIPC) is a systemic phenomenon, only a few studies have focused on the elucidation of its mechanisms of action especially in the clinical setting. Therefore, the aim of this study is to evaluate the acute microcirculatory effects of remote ischemic preconditioning on a distinct cutaneous location at the lower extremity which is typically used as a harvesting site for free flap reconstructive surgery in a human in-vivo setting.


METHODS
Microcirculatory data of 27 healthy subjects (25 males, age 24 ± 4 years, BMI 23.3) were evaluated continuously at the anterolateral aspect of the left thigh during RIPC using combined Laser-Doppler and photospectrometry (Oxygen-to-see, Lea Medizintechnik, Germany). After baseline microcirculatory measurement, remote ischemia was induced using a tourniquet on the contralateral upper arm for three cycles of 5 min.


RESULTS
After RIPC, tissue oxygen saturation and capillary blood flow increased up to 29% and 35% during the third reperfusion phase versus baseline measurement, respectively (both p = 0.001). Postcapillary venous filling pressure decreased statistically significant by 16% during second reperfusion phase (p = 0.028).


CONCLUSION
Remote intermittent ischemic preconditioning affects cutaneous tissue oxygen saturation, arterial capillary blood flow and postcapillary venous filling pressure at a remote cutaneous location of the lower extremity. To what extent remote preconditioning might ameliorate reperfusion injury in soft tissue trauma or free flap transplantation further clinical trials have to evaluate.


TRIAL REGISTRATION
ClinicalTrials.gov: NCT01235286.
Literature Review of Air Pollution Control Biofilters and Biotrickling Filters for Odor and Volatile Organic Compound Removal

A literature study was conducted to compare the feasibility of biofilters and biotrickling filters for the treatment of complex odorous waste air containing hydrogen sulfide (H2S), organic reduced sulfur compounds, and chlorinated and nonchlorinated volatile organic compounds (VOCs). About 40 pilot-plant studies and full-scale applications at wastewater treatment plants and other facilities were reviewed. Reactor design and pollutant removal efficiencies were summarized in tables for easy reference and for a perspective on the current state of the art, and to allow comparison between different projects. The survey indicated that both biofilters and biotrickling filters are capable of combining a high H2S and odor removal efficiency with VOC removal. Apart from odor abatement, biological treatment therefore holds promise for reducing the overall toxicity and potential carcinogenicity of VOCcontaining odorous waste air from wastewater treatment plants and other facilities. VOC removal efficiencies were in general lower than those of H2S and odor, although concentrations of individual VOC species were relatively low. This indicates that for effective treatment of VOC-containing odorous waste air, the design and operation should emphasize VOC removal as the rate-limiting parameter. © 2005 American Institute of Chemical Engineers Environ Prog, 24: 254–267, 2005
A model for measuring e-learning systems success in universities

0957-4174/$ see front matter 2012 Elsevier Ltd. A http://dx.doi.org/10.1016/j.eswa.2012.03.028 ⇑ Corresponding author. Tel./fax: +98 2182883637. E-mail addresses: ar_hassanzadeh@modares.ac.ir com (A. Hassanzadeh), ftmh_kanani@yahoo.com (F. K (S. Elahi). 1 Measuring e-learning systems success. In the era of internet, universities and higher education institutions are increasingly tend to provide e-learning. For suitable planning and more enjoying the benefits of this educational approach, a model for measuring success of e-learning systems is essential. So in this paper, we try to survey and present a model for measuring success of e-learning systems in universities. For this purpose, at first, according to literature review, a conceptual model was designed. Then, based on opinions of 33 experts, and assessing their suggestions, research indicators were finalized. After that, to examine the relationships between components and finalize the proposed model, a case study was done in 5 universities: Amir Kabir University, Tehran University, Shahid Beheshti University, Iran University of Science & Technology and Khaje Nasir Toosi University of Technology. Finally, by analyzing questionnaires completed by 369 instructors, students and alumni, which were e-learning systems user, the final model (MELSS Model). 2012 Elsevier Ltd. All rights reserved.
Long-term outcomes for HIV-infected infants less than 6 months of age at initiation of lopinavir/ritonavir combination antiretroviral therapy.

OBJECTIVE
To investigate the longitudinal pharmacokinetics, safety and efficacy of lopinavir/ritonavir (LPV/r) in HIV-infected infants initiating combination antiretroviral therapy (cART) between 2 weeks and 6 months of age.


METHOD
A prospective, open-label, multicenter Phase I/II study of LPV/r-based cART at a dose of 300/75 mg/m(2)/dose LPV/r twice daily. Intensive pharmacokinetic sampling at 12 months of age and quarterly predose LPV concentrations were collected and safety, virologic and immunologic responses were monitored every 4-12 weeks up to 252 weeks.


RESULTS
Thirty-one HIV-infected infants enrolled into two age cohorts, 14 days to <6 weeks and 6 weeks to <6 months; 29 completed ≥48 weeks of follow-up (median = 123 weeks, range 4-252). At 12 months of age, median LPV area under the curve was comparable for both age cohorts and similar to older children and adults. At week 48, 22 of 31 patients (71%) had HIV-1 RNA <400 copies/ml and 11 of 15 (73%) had <50 copies/ml; 29 of 31 achieved HIV-1 RNA <400 copies/ml on study treatment and 19 (66%) remained durably suppressed until the end of study; viral suppression correlated with a higher percentage of predose time points exceeding the LPV target of 1 μg/ml (92 vs. 71%, P = 0.002).


CONCLUSION
LPV/r at 300/75 mg/m(2)/dose as part of a cART regimen resulted in viral suppression through 96 weeks of treatment in >65% of young infants. Due to initially low LPV exposure in infants <6 weeks of age, frequent dose adjustment for weight gain is advisable and consideration should be given to studying a higher dose for very young infants.
Multiple Café au Lait Spots in a Group of Fair-Skinned Children without Signs or Symptoms of Neurofibromatosis Type 1.

BACKGROUND
The presence of six or more café au lait (CAL) spots is a criterion for the diagnosis of neurofibromatosis type 1 (NF-1). Children with multiple CAL spots are often referred to dermatologists for NF-1 screening. The objective of this case series is to characterize a subset of fair-complected children with red or blond hair and multiple feathery CAL spots who did not meet the criteria for NF-1 at the time of their last evaluation.


METHODS
We conducted a chart review of eight patients seen in our pediatric dermatology clinic who were previously identified as having multiple CAL spots and no other signs or symptoms of NF-1.


RESULTS
We describe eight patients ages 2 to 9 years old with multiple, irregular CAL spots with feathery borders and no other signs or symptoms of NF-1. Most of these patients had red or blond hair and were fair complected. All patients were evaluated in our pediatric dermatology clinic, some with a geneticist. The number of CAL spots per patient ranged from 5 to 15 (mean 9.4, median 9).


CONCLUSION
A subset of children, many with fair complexions and red or blond hair, has an increased number of feathery CAL spots and appears unlikely to develop NF-1, although genetic testing was not conducted. It is important to recognize the benign nature of CAL spots in these patients so that appropriate screening and follow-up recommendations may be made.
Robust digital image-in-image watermarking algorithm using the fast Hadamard transform

In this paper, a robust and efficient digital image watermarking algorithm using the fast Hadamard transform (FHT) is proposed for the copyright protection of digital images. This algorithm can embed or hide an entire image or pattern as a watermark such as a company’s logo or trademark directly into the original image. The performance of the proposed algorithm is evaluated using Stirmark 3.1which consists of 90 different types of image attacks. Results show that the proposed algorithm is very robust and can survive most of the Stirmark attacks. These attacks were tested on a number of test images of size 512×512×8 bits, embedded with a watermark image of size 64×64×8 bits. The simplicity of the fast Hadamard transform also offers a significant advantage in shorter processing time and ease of hardware implementation than other orthogonal transforms, such as the discrete cosine transform and wavelet transform.
NUTRISCORE: A new nutritional screening tool for oncological outpatients.

OBJECTIVES
The aim of this study was to design a new nutritional screening tool (NUTRISCORE) to detect nutritional risk in outpatients with cancer.


METHODS
A multicenter, cross-sectional study was conducted. We randomly selected outpatients receiving onco-specific, palliative, or symptomatic treatment for malignant neoplasms (including solid tumors and hematologic malignancies). These patients were assessed using the NUTRISCORE tool, the Malnutrition Screening Tool (MST), and the Patient-Generated Subjective Global Assessment (PG-SGA) to detect risk for malnutrition. The new tool included questions regarding the cancer site and active treatment. Sensitivity, specificity, and positive and negative predictive values were calculated for NUTRISCORE and MST using the PG-SGA as a reference method.


RESULTS
We evaluated 394 patients. According to NUTRISCORE, 22.6% were at risk for malnutrition. The MST detected a risk in 28.2%, and the PG-SGA found that 19% were malnourished or at nutritional risk. Using the PG-SGA as a reference method, the MST had a sensitivity of 84% and a specificity of 85.6%, whereas NUTRISCORE exceeded these values, at 97.3% sensitivity and 95.9% specificity. The better performance of NUTRISCORE as compared with MST was confirmed by the receiver operating characteristic curve analysis, with area under the curve values of 0.95 (95% confidence interval, 0.92-0.98) for NUTRISCORE and 0.84 (95% confidence interval, 0.79-0.89) for the MST.


CONCLUSIONS
NUTRISCORE has been found to be a novel, fast, and valid nutritional screening tool for outpatients with cancer. Its simplicity and high level of accuracy in detecting nutritional risk facilitates its applicability.
Big Data Analytics

INTRODUCTION In recent years “big data” has become something of a buzzword in business, computer science, information studies, information systems, statistics, and many other fields. As technology continues to advance, we constantly generate an ever-increasing amount of data. This growth does not differentiate between individuals and businesses, private or public sectors, institutions of learning and commercial entities. It is nigh universal and therefore warrants further study.
Positive affect and incidence of frailty in elderly women caregivers and noncaregivers: results of Caregiver-Study of Osteoporotic Fractures.

OBJECTIVES
To determine whether positive affect is associated with a lower incidence of frailty over 2 years in elderly community-dwelling women and to test the stress-buffering hypothesis by evaluating whether these associations differed in caregivers and noncaregivers.


DESIGN
Prospective cohort study with three annual interviews conducted in four U.S. communities between 1999 and 2004.


SETTING
Home-based interviews.


PARTICIPANTS
Three hundred thirty-seven caregiver and 617 noncaregiver participants from the Caregiver-Study of Osteoporotic Fractures (Caregiver-SOF) who were not frail at the baseline Caregiver-SOF interview.


MEASUREMENTS
High and low positive affect and depressive symptoms were derived from the baseline 20-item Center for Epidemiologic Studies Depression Scale. Frailty was the development of three or more indicators (weight loss, exhaustion, slow walking speed, or weak grip strength) at the first or second follow-up interview.


RESULTS
Respondents' mean age was 81.2. Caregivers and noncaregivers had similar levels of positive affect (56.3% vs 58.3%) and frailty incidence (15.4% vs 15.9%) but differed in perceived stress (mean Perceived Stress Scale score 16.7 vs 14.8, P<.001). Frailty risk was lower in respondents with high positive affect than in those with low positive affect in the total sample (adjusted hazard ratio (HR)=0.49, 95% confidence interval (CI)=0.35-0.70), caregivers (adjusted HR=0.44, 95% CI=0.24-0.80) and noncaregivers (adjusted HR=0.50, 95% CI=0.32-0.77).


CONCLUSION
These findings add to the evidence that positive affect protects against health decline in older adults, although it had no additional stress-buffering effect on health in elderly caregivers.
Who interacts on the Web?: The intersection of users' personality and social media use

In the increasingly user-generated Web, users’ personality traits may be crucial factors leading them to engage in this participatory media. The literature suggests factors such as extraversion, emotional stability and openness to experience are related to uses of social applications on the Internet. Using a national sample of US adults, this study investigated the relationship between these three dimensions of the BigFive model and social media use (defined as use of social networking sites and instant messages). It also examined whether gender and age played a role in that dynamic. Results revealed that while extraversion and openness to experiences were positively related to social media use, emotional stability was a negative predictor, controlling for socio-demographics and life satisfaction. These findings differed by gender and age. While extraverted men and women were both likely to be more frequent users of social media tools, only the men with greater degrees of emotional instability were more regular users. The relationship between extraversion and social media use was particularly important among the young adult cohort. Conversely, being open to new experiences emerged as an important personality predictor of social media use for the more mature segment of the sample. 2009 Elsevier Ltd. All rights reserved.
The Beilinson-Bernstein correspondence for quantized enveloping algebras

Abstract.Theory of the quantized flag manifold as a quasi-scheme (non-commutative scheme) has been developed by Lunts-Rosenberg [15]. They have formulated an analogue of the Beilinson-Bernstein correspondence using the q-differential operators introduced in their earlier paper [14]. In this paper we shall establish its modified version using a class of q-differential operators, which is (possibly) smaller than the one in [14].
An electronic delphi study to establish pediatric intensive care nursing research priorities in twenty European countries*.

OBJECTIVES
To identify and to establish research priorities for pediatric intensive care nursing science across Europe.


DESIGN
A modified three-round electronic Delphi technique was applied. Questionnaires were translated into seven different languages.


SETTING
European PICUs.


PARTICIPANTS
The participants included pediatric intensive care clinical nurses, managers, educators, and researchers. In round 1, the qualitative responses were analyzed by content analysis and a list of research statements and domains was generated. In rounds 2 and 3, the statements were ranked on a scale of one to six (not important to most important). Mean scores and SDs were calculated for rounds 2 and 3.


INTERVENTIONS
None.


MEASUREMENTS AND MAIN RESULTS
Round 1 started with 90 participants, with round 3 completed by 64 (71%). The seven highest ranking statements (≥ 5.0 mean score) were related to end-of-life care, decision making around forgoing and sustaining treatment, prevention of pain, education and competencies for pediatric intensive care nurses, reducing healthcare-associated infections, identifying appropriate nurse staffing levels, and implementing evidence into nursing practice. Nine research domains were prioritized, and these were as follows: 1) clinical nursing care practices, 2) pain and sedation, 3) quality and safety, 4) respiratory and mechanical ventilation, 5) child- and family-centered care, 6) ethics, 7) professional issues in nursing, 8) hemodynamcis and resuscitation, and 9) trauma and neurocritical care.


CONCLUSIONS
The results of this study inform the European Society of Pediatric and Neonatal Intensive Care's nursing research agenda in the future. The results allow nurse researchers within Europe to encourage collaborative initiatives for nursing research.
Osseous sarcoidosis: clinical characteristics, treatment, and outcomes--experience from a large, academic hospital.

OBJECTIVE
Osseous sarcoidosis has been infrequently reported. We aimed to characterize the distribution of lesions, clinical presentation, treatment, and outcomes for osseous sarcoidosis.


METHODS
Cases of osseous sarcoidosis were identified by directed inquiry to clinicians and electronic query. Cases were defined as having pathologic evidence of non-caseating granulomas on bone biopsy or evidence of osseous lesions on imaging attributable to sarcoidosis in patients with known sarcoidosis. Detailed characteristics were obtained by medical record review.


RESULTS
We identified a total of 20 cases of osseous sarcoidosis. Osseous lesions were detected by imaging during the initial sarcoidosis presentation in 60% of cases. In those who had a prior diagnosis of sarcoidosis, the median duration of sarcoidosis before detection of osseous involvement was 4.3 years. Symptoms were present in 50% of cases. All cases had more than one bone involved. The axial skeleton was involved in the majority of cases (90%), primarily the pelvis and the lumbar spine. Most cases required no treatment (55%); a minority of cases (45%) were treated, most often with prednisone, methotrexate, or hydroxychloroquine. Two cases required multiple immunosuppressants, including tumor necrosis factor inhibitors, for refractory symptomatic osseous sarcoidosis. Treated cases were younger than those who were untreated. At last follow-up, most cases (85%) were asymptomatic from osseous lesions.


CONCLUSIONS
In this case series of osseous sarcoidosis from a single center, most patients had multiple bones affected and had other systemic manifestations of sarcoidosis. A minority required treatment for relief of symptoms, and most cases were asymptomatic at last follow-up.
The Connected Car in the Cloud: A Platform for Prototyping Telematics Services

The Connected-Car Prototyping Platform provides both a back end for applications interacting with connected cars and an abstraction of such connected devices for developers. It also provides services such as identity management and data storage. Its main purposes are experimentation, prototyping, evaluation of ideas, and reduction of time-to-market for successful applications.