LLukas22/scidocs huggingface dataset:
An Effective and Secure Key-Management Scheme for Hierarchical Access Control in E-Medicine System

Recently several hierarchical access control schemes are proposed in the literature to provide security of e-medicine systems. However, most of them are either insecure against ‘man-in-the-middle attack’ or they require high storage and computational overheads. Wu and Chen proposed a key management method to solve dynamic access control problems in a user hierarchy based on hybrid cryptosystem. Though their scheme improves computational efficiency over Nikooghadam et al.’s approach, it suffers from large storage space for public parameters in public domain and computational inefficiency due to costly elliptic curve point multiplication. Recently, Nikooghadam and Zakerolhosseini showed that Wu–Chen’s scheme is vulnerable to man-in-the-middle attack. In order to remedy this security weakness in Wu–Chen’s scheme, they proposed a secure scheme which is again based on ECC (elliptic curve cryptography) and efficient one-way hash function. However, their scheme incurs huge computational cost for providing verification of public information in the public domain as their scheme uses ECC digital signature which is costly when compared to symmetric-key cryptosystem. In this paper, we propose an effective access control scheme in user hierarchy which is only based on symmetric-key cryptosystem and efficient one-way hash function. We show that our scheme reduces significantly the storage space for both public and private domains, and computational complexity when compared to Wu–Chen’s scheme, Nikooghadam–Zakerolhosseini’s scheme, and other related schemes. Through the informal and formal security analysis, we further show that our scheme is secure against different attacks and also man-in-the-middle attack. Moreover, dynamic access control problems in our scheme are also solved efficiently compared to other related schemes, making our scheme is much suitable for practical applications of e-medicine systems.
Mathematical Models of Flow Shop and Job Shop Scheduling Problems

In this paper, mathematical models for permutation flow shop scheduling and job shop scheduling problems are proposed. The first problem is based on a mixed integer programming model. As the problem is NP-complete, this model can only be used for smaller instances where an optimal solution can be computed. For large instances, another model is proposed which is suitable for solving the problem by stochastic heuristic methods. For the job shop scheduling problem, a mathematical model and its main representation schemes are presented. Keywords—Flow shop, job shop, mixed integer model, representation scheme.
THE STRENGTH OF WEAK TIES : A NETWORK THEORY REVISITED

of Ph.D. dissertation, University of Haifa, Israel.
SDG-Pro: a programming framework for software-defined IoT cloud gateways

Recently, emerging IoT cloud systems create numerous opportunities for a variety of stakeholders in terms of optimizing their existing business processes, as well as developing novel cross-organization and cross-domain applications. However, developers of such systems face a plethora of challenges, mainly due to complex dependencies between the application business logic and the underlying IoT cloud infrastructure, as well as difficulties to provision and govern vast, geographically distributed IoT cloud resources. In this paper, we introduce SDG-Pro – a novel programming framework for software-defined IoT cloud systems. The main features of our framework include programming abstractions: Software-Defined Gateways, Intents, Intent Scopes, and Data and Control Points, as well as provisioning and governance APIs that allow for programmatic management of software-defined gateways throughout their entire lifecycle. The SDG-Pro framework enables easier, efficient and more intuitive development of IoT cloud applications. It promotes the everything-as-code paradigm for IoT cloud applications in order to provide a uniform, programmatic view on the entire development process. To illustrate the feasibility of our framework to support development of IoT cloud applications, we evaluate it using a real-world case study on managing fleets of electric vehicles.
Vestibular Cues and Virtual Environments: Choosing the Magnitude of the Vestibular Cue

The design of virtual environments usually concentrates on constructing a realistic visual simulation and ignores the non-visual cues normally associated with moving through an environment. The lack of the normal complement of cues may contribute to cybersickness and may a ect operator performance. In [5] we described the e ect of adding vestibular cues during passive linear motion and showed an unexpected dominance of the vestibular cue in determining the magnitude of the perceived motion. Here we vary the relative magnitude of the visual and vestibular cues and describe a simple linear summation model that predicts the resulting perceived magnitude of motion. The model suggests that designers of virtual reality displays should add vestibular information in a ratio of one to four with the visual motion to obtain convincing and accurate performance.
NEAL: A Neurally Enhanced Approach to Linking Citation and Reference

As a way to tackle Task 1A in CL-SciSumm 2016, we introduce a composite model consisting of TFIDF and Neural Network (NN), the latter being a adaptation of the embedding model originally proposed for the Q/A domain [2, 7]. We discuss an experiment using a development data, results thereof, and some remaining issues.
Bihemispheric brain stimulation facilitates motor recovery in chronic stroke patients.

OBJECTIVE
Motor recovery after stroke depends on the integrity of ipsilesional motor circuits and interactions between the ipsilesional and contralesional hemispheres. In this sham-controlled randomized trial, we investigated whether noninvasive modulation of regional excitability of bilateral motor cortices in combination with physical and occupational therapy improves motor outcome after stroke.


METHODS
Twenty chronic stroke patients were randomly assigned to receive 5 consecutive sessions of either 1) bihemispheric transcranial direct current stimulation (tDCS) (anodal tDCS to upregulate excitability of ipsilesional motor cortex and cathodal tDCS to downregulate excitability of contralesional motor cortex) with simultaneous physical/occupational therapy or 2) sham stimulation with simultaneous physical/occupational therapy. Changes in motor impairment (Upper Extremity Fugl-Meyer) and motor activity (Wolf Motor Function Test) assessments were outcome measures while functional imaging parameters were used to identify neural correlates of motor improvement.


RESULTS
The improvement of motor function was significantly greater in the real stimulation group (20.7% in Fugl-Meyer and 19.1% in Wolf Motor Function Test scores) when compared to the sham group (3.2% in Fugl-Meyer and 6.0% in Wolf Motor Function Test scores). The effects outlasted the stimulation by at least 1 week. In the real-stimulation group, stronger activation of intact ipsilesional motor regions during paced movements of the affected limb were found postintervention whereas no significant activation changes were seen in the control group.


CONCLUSIONS
The combination of bihemispheric tDCS and peripheral sensorimotor activities improved motor functions in chronic stroke patients that outlasted the intervention period. This novel approach may potentiate cerebral adaptive processes that facilitate motor recovery after stroke.


CLASSIFICATION OF EVIDENCE
This study provides Class I evidence that for adult patients with ischemic stroke treated at least 5 months after their first and only stroke, bihemispheric tDCS and simultaneous physical/occupational therapy given over 5 consecutive sessions significantly improves motor function as measured by the Upper Extremity Fugl-Meyer assessment (raw change treated 6.1 ± 3.4, sham 1.2 ± 1.0).
Switching to iloperidone: An omnibus of clinically relevant observations from a 12-week, open-label, randomized clinical trial in 500 persons with schizophrenia.

OBJECTIVE
To describe secondary analyses from a 12-week, randomized, open-label trial where adult schizophrenia outpatients receiving risperidone, olanzapine, or aripiprazole were switched to iloperidone.


METHODS
Patients were randomized into two groups: one where the antecedent antipsychotic dose was titrated downwards to zero over 2 weeks (n=240), and the other group where the antecedent antipsychotic was abruptly stopped (n=260). Adaptations of the Clinical Global Impression scale were used to evaluate clinical changes. Other assessments included the reporting of adverse events (AEs), study discontinuation, body weight, and metabolic variables.


RESULTS
Improvement was steady throughout the study for both gradual- and immediate-switch groups starting at Week 1 and continuing through Week 12. Discontinuations due to AEs in the first 2 weeks of treatment were higher for the immediate-switch group compared with the gradual-switch group (10.8% vs. 5.4%, NNT 19, 95% CI 10-151). Fewer patients in the gradual-switch group experienced dizziness as an AE, whereas a higher percentage of patients in the immediate-switch group exhibited earlier onset of a therapeutic response within the first 2 weeks; both groups were comparable thereafter with low rates of dizziness and similar efficacy outcomes.


CONCLUSIONS
Switching to iloperidone can be accomplished either with a gradual crossover or immediate discontinuation of the prior antipsychotic; however, the immediate-switch method is associated with greater proportion of initial dizziness. The observed outcomes are consistent with what has been previously reported regarding iloperidone's favorable akathisia/EPS profile and modest impact on somnolence/sedation, body weight, and metabolic variables.
Parallel Computer Algebra 1

2 Building and implementing parallel algorithms in the area of computer algebra has become an important thread of research for more than a decade with the increasing availability of various parallel architectures, from dedicated machines to network of workstations. New algorithms have been built and implemented to solve high performance computing challenges. The aim of this tutorial is to give an introduction to parallel algorithms in computer algebra, from the building of an efficient algorithm to its effective implementation on a given architecture. Parallel computer algebra systems, that exploit the parallelism of an algorithm on a given architecture, play a central role to ensure efficient executions. Due to the variety of parallel programming models, several such systems propose various approaches to express parallelism, from data distribution to functional parallelism. After an introduction to algorithmic techniques and classical programming models, the tuto-rial will focus on parallel computer algebra systems, parallel linear algebra algorithms and their effective implementations. The tutorial is organized in four parts : 1. Parallel efficient algorithms. The major techniques used to build efficient algorithms on theoretical machine models are presented. They are illustrated by various basic computer algebra algorithms. Due to the non-uniformity of memory access, communication complexity is a key point to take into account in the analysis of the algorithm. 2. Programming models and scheduling. To combine expressive power and portability, several programming models have been proposed, from message-passing to bulk-synchronous programming and functional languages. The inherent overhead due to their emulation makes each of them suited to a specific range of applications. 3. Parallel computer algebra systems. Different parallel systems are proposed that are based on the coupling of a sequential system and a parallel programming model. They are often guided by the classes of applications on which they have been experimented. 4. Parallel linear algebra. The parallelization techniques introduced before are illustrated on various research problems in parallel linear algebra : system solving, gcd, rank and normal forms.
Joint strength and interfacial microstructure between Sn–Ag–Cu and Sn–Zn–Bi solders and Cu substrate

In the present research, in order to fundamentally investigate the strength and interfacial microstructure of the joints between Sn–3.5Ag– 0.7Cu (SAC) and Sn–8Zn–3Bi (SZB) solders and Cu, examinations using the standardized solder joint specimen for measuring the shear strength were performed. The effects of the addition of Ag, Bi and Pb to the solders, which are the ingredients of possible lead plating materials of quad plat package, solder layer thickness and aging treatments ranging from 358 to 423 K were investigated. The SAC base solder joints, whose strength hardly degraded after aging, were more reliable than the SZB base solder joints. Since no detrimental effect of the Bi or Pb addition was recognized, the lead plating materials are found to have no significant effect on the strength of the SAC solder joints. Although the SZB base solder joints had higher strength than the SAC base solder joints in as-soldered condition, a significant degradation of the joint strength occurred after aging. In the case of thinner solder layer of 20 mm, the Cu6Sn5 layer that formed at both the solder/Cu5Zn8 and Cu5Zn8/Cu interfaces after aging caused the fracture of the solder joints and resulted in the degradation of the joint strength. In the case of thicker solder layer of 100 mm, the Cu5Zn8 interfacial layer continuously grew during aging, which caused the fracture of the solder joints and resulted in the decrease in the joint strength. As for the effect of the addition elements, while Pb addition caused a marked degradation of the joint strength, Ag addition and Bi addition had no detrimental effect on the strength of the solder joints. In particular, the joint with the Ag addition solder had the better strength in the case of thinner solder layer. Thus, as for lead plating for the SZB solder, Sn–Pb should be avoided and Sn–Bi or Sn–Ag as Pb-free plating has no detrimental effect on the joint strength. In particular, Sn–Ag plating is preferable in the viewpoint of the joint strength. q 2003 Elsevier Ltd. All rights reserved.
Comparison of the safety and efficacy of 3 iron sucrose iron maintenance regimens in children, adolescents, and young adults with CKD: a randomized controlled trial.

BACKGROUND
Iron deficiency is a common cause of anemia in young persons with chronic kidney disease (CKD). Iron repletion with intravenous (IV) iron formulations has been studied in children; maintenance IV iron regimens have not been reported extensively.


STUDY DESIGN
A multicenter randomized trial of IV iron sucrose.


SETTING & PARTICIPANTS
145 children, adolescents, and young adults with CKD receiving erythropoiesis-stimulating agent (ESA) therapy were stratified by dialysis category (hemodialysis, peritoneal dialysis, or non-dialysis dependent) and weight (<50 and ≥50 kg).


INTERVENTION
Patients were randomly assigned to 1 of 3 dosing arms: 0.5, 1.0, or 2.0 mg/kg (maximum single dose, 100 mg), stratified into hemodialysis versus nonhemodialysis (peritoneal dialysis or non-dialysis-dependent CKD) groups. Patients treated with hemodialysis received study medication once every other week for 6 doses. Patients in the nonhemodialysis group received study medication once every 4 weeks for 3 doses.


OUTCOMES
We assessed adverse event rates between dosing groups. The main clinical end point was a composite of hemoglobin level ≥10.5-14.0 g/dL, inclusive; transferrin saturation ≥20%-50%, inclusive; and stable ESA dosing (±25% of baseline dose).


RESULTS
Between-group difference for composite clinical end point rate attainment was -3.9% (95% CI, -21.4% to 13.7%) for the 1.0-mg/kg group versus 0.5-mg/kg group, +3.9% (95% CI, -15.1% to 23.0%) for the 2-mg/kg group versus 0.5-mg/kg group, and +7.8% (95% CI, -10.9% to 26.5%) for the 2-mg/kg group versus 1-mg/kg group. No differences were noted between regimens in reported adverse effects, which were all minor.


LIMITATIONS
Absence of a control group receiving no IV iron. Short duration of intervention and observation. A small proportion of patients having achieved the primary clinical outcome.


CONCLUSIONS
IV iron sucrose at a dose of 0.5 mg/kg at the intervals prescribed is noninferior to higher doses in maintaining hemoglobin levels >10.5 g/dL in children, adolescents, and young adults receiving ESA therapy.
Message from technical program chair

We would like to take this opportunity to express our warm welcome to all of you to the ECTI-CON2010: The 2010 ECTI International Conference on Electrical Engineering/Electronics, Computer, Telecommunications and Information Technology and to Chiang Mai, one of the most beautiful cities of Thailand, the land of smiles.
Glycosylation of an immunoglobulin produced from a murine hybridoma cell line: the effect of culture mode and the anti-apoptotic gene, bcl-2.

The impact of bcl-2 over-expression on the glycosylation pattern of an antibody produced by a bcl-2 transfected hybridoma cell line (TB/C3.bcl-2) was investigated in suspension batch, continuous and high cell density culture (Flat hollow fibre, Tecnomouse system). In all culture modes bcl-2 over-expression resulted in higher cell viability. Analysis of the glycans from the IgG of batch cultures showed that >95% of the structures were neutral core fucosylated asialo biantennary oligosaccharides with variable terminal galactosylation (G0f, G1f and G2f) consistent with previous analysis of glycans from the conserved site at Asn-297 of the IgG protein. The galactosylation index (GI) was determined as an indicator of the glycan profile (=(G2 + 0.5* G1)/(G0 + G1 + G2)). GI values in control cultures were comparable to bcl-2 cultures during exponential growth (0.53) but declined toward the end of the culture when there was a loss in cell viability. Low dilution rates in chemostat culture were associated with reduced galactosylation of the IgG glycans in both cell lines. However, at the higher dilution rates the GI for IgG was consistently higher in the TB/C3.bcl-2 cultures. In the hollow fibre bioreactor the galactosylation of the IgG glycans was considerably lower than in suspension batch or continuous cultures with GI values averaging 0.38. Similar low galactosylation values have been found previously for high density cell cultures and these are consistent with the low values obtained when the dissolved oxygen level is maintained at a low value (10%) in controlled suspension cultures of hybridomas.
The composition of normative groups and diagnostic decision making: shooting ourselves in the foot.

PURPOSE
The normative group of a norm-referenced test is intended to provide a basis for interpreting test scores. However, the composition of the normative group may facilitate or impede different types of diagnostic interpretations. This article considers who should be included in a normative sample and how this decision must be made relative to the purpose for which a test is intended.


METHOD
The way in which the composition of the normative sample affects classification accuracy is demonstrated through a test review followed by a simulation study. The test review examined the descriptions of the normative group in a sample of 32 child language tests. The mean performance reported in the test manual for the sample of language impaired children was compared with the sample's norms, which either included or excluded children with language impairment. For the simulation, 2 contrasting normative procedures were modeled. The first procedure included a mixed group of representative cases (language impaired and normal cases). The second procedure excluded the language impaired cases from the norm.


RESULTS
Both the data obtained from test manuals and the data simulation based on population characteristics supported our claim that use of mixed normative groups decreases the ability to accurately identify language impairment. Tests that used mixed norms had smaller differences between the normative and language impaired groups in comparison with tests that excluded children with impairment within the normative sample. The simulation demonstrated mixed norms that lowered the group mean and increased the standard deviation, resulting in decreased classification accuracy.


CONCLUSIONS
When the purpose of testing is to identify children with impaired language skills, including children with language impairment in the normative sample can reduce identification accuracy.
Gastric cancer: pathogenesis, risks, and prevention

Intestinal (IGCA) and diffuse (DGCA) gastric adenocarcinomas, the two main microscopic subtypes, are dissimilar regarding their epidemiological and demographic characteristics. Both tumor types comprise approximately 40% of all gastric adenocarcinomas. The DGCAs more often occur in young age groups, more often affect the corpus, and are less infrequently associated with atrophic gastritis and intestinal metaplasia than the IGCAs. The risk of both DGCA and IGCA is increased in the presence ofHelicobacter pylori infection, and the risk rises with increases in grade and extent of atrophic gastritis and intestinal metaplasia. It is likely that the development of up to 80% of the DGCAs and IGCAs can be prevented with early eradication of theH. pylori infection. The pathogenesis and morphogenesis of DGCAs are unknown, but the morphogenesis of IGCAs includes identifiable precancerous conditions such as atrophie gastritis and intestinal metaplasia as well as identifiable precancerous lesions (adenomas, dysplasias). Atrophic gastritis is a direct result of theH. pylori infestation. Atrophic gastritis, for unknown reasons, appears in more than half of the infected subjects during their lifetime.H. pylori gastritis triggers a variety of reactions, with the reaction cascades resulting in errors of the cell genome and ending up as neoplastic tumors.
Castleman's disease—a two compartment model of HHV8 infection

Castleman's disease is a primary infectious disease of the lymph node that causes local symptoms or a systemic inflammatory syndrome. Histopathology reveals a destroyed lymph node architecture that can range from hyaline-vascular disease to plasma-cell disease. Viral interleukin 6 (vIL-6) produced during the replication of human herpesvirus type 8 (HHV8) is the key driver of systemic inflammation and cellular proliferation. Stage progression of Castleman's disease results from switches between viral latency and lytic replication, and lymphatic and hematogenous spread. Multicentric plasma-cell disease in HIV-1 patients is associated with HHV8 infection. Polyclonal plasmablast proliferation escapes control in the germinal center with eventual malignant transformation into non-Hodgkin lymphoma. Surgery produces excellent results in unicentric disease, while multicentric disease responds to anti-CD20 therapy or IL-6 and chemotherapy. Lymphovascular endothelium and naive B cells are infectious reservoir-opening options for antiangiogenic and anti-CD19 strategies to enhance outcomes in patients with systemic disease.
A model for life time evaluation of closed electrical contacts

A model for evaluating the lifetime of closed electrical contacts was described. The model is based on the diffusion of oxidizing agent into the contact zone. The results showed that there is good agreement between the experimental data as reported by different authors in the literature and the derived expressions for the limiting value of contact lifetime.