LLukas22/scidocs huggingface dataset:
Efficacy of clear aligners in controlling orthodontic tooth movement: a systematic review.

OBJECTIVE
To assess the scientific evidence related to the efficacy of clear aligner treatment (CAT) in controlling orthodontic tooth movement.


MATERIALS AND METHODS
PubMed, PMC, NLM, Embase, Cochrane Central Register of Controlled Clinical Trials, Web of Knowledge, Scopus, Google Scholar, and LILACs were searched from January 2000 to June 2014 to identify all peer-reviewed articles potentially relevant to the review. Methodological shortcomings were highlighted and the quality of the studies was ranked using the Cochrane Tool for Risk of Bias Assessment.


RESULTS
Eleven relevant articles were selected (two Randomized Clinical Trials (RCT), five prospective non-randomized, four retrospective non-randomized), and the risk of bias was moderate for six studies and unclear for the others. The amount of mean intrusion reported was 0.72 mm. Extrusion was the most difficult movement to control (30% of accuracy), followed by rotation. Upper molar distalization revealed the highest predictability (88%) when a bodily movement of at least 1.5 mm was prescribed. A decrease of the Little's Index (mandibular arch: 5 mm; maxillary arch: 4 mm) was observed in aligning arches.


CONCLUSIONS
CAT aligns and levels the arches; it is effective in controlling anterior intrusion but not anterior extrusion; it is effective in controlling posterior buccolingual inclination but not anterior buccolingual inclination; it is effective in controlling upper molar bodily movements of about 1.5 mm; and it is not effective in controlling rotation of rounded teeth in particular. However, the results of this review should be interpreted with caution because of the number, quality, and heterogeneity of the studies.
B and E MADS-box genes determine the perianth formation in Cymbidium goeringii Rchb.f.

Cymbidium goeringii Rchb.f. is an important ornamental plant with a striking well-differentiated lip. Its complex floral architecture presents an exciting opportunity to examine perianth development. In flowering plants, class A, B and E floral homeotic genes play key roles in the specification of perianth identity. In this study, we used a cDNA library of wild-type C. goeringii flower buds for transcriptome sequencing. Eighteen candidate class A, B and E genes (including AP1/FUL-, AP2-, DEF-, GLO-, SEP- and AGL6-like genes) were identified. Quantitative real time polymerase chain reaction (qRT-PCR) results showed that CgDEF1, CgSEP2 and CgAGL6-1 were strongly detected only in the sepals and petals and were significantly downregulated in the lips. CgDEF3, CgDEF4 and CgAGL6-3 were highly expressed in the lips and lip-like petals but were only minimally detected in the sepals. Yeast two-hybrid analysis indicated that CgDEF1 and CgGLO formed a heterodimer. CgAGL6-1/CgSEP2 and CgDEF1 formed higher-order protein complexes with the assistance of the CgGLO protein, and both CgAGL6-1 and CgSEP2 formed a heterodimer. CgDEF3/CgDEF4 could interact independently with CgGLO and CgAGL6-3, respectively, while CgDEF3 and CgDEF4 also formed heterodimers with the assistance of the CgGLO. Based on a comprehensive analysis relating these gene expression patterns to protein interaction profiles, the mechanism of sepal/petal/lip determination was studied in C. goeringii. Furthermore, a hypothesis explaining the sepal/petal/lip determination of C. goeringii is proposed. The lip-quartet (CgDEF3/CgDEF4/CgAGL6-3/CgGLO) promoted lip formation, whereas the sepal/petal-quartet (CgDEF1/CgAGL6-1/CgSEP2/CgGLO) promoted sepal/petal formation. These results enrich the current knowledge regarding the mechanism and pathways of perianth formation in orchids.
Benchmarking open government: An open data perspective

Available online 3 April 2014
Genetic programming for credit scoring: The case of Egyptian public sector banks

Credit scoring has been widely investigated in the area of finance, in general, and banking sectors, in particular. Recently, genetic programming (GP) has attracted attention in both academic and empirical fields, especially for credit problems. The primary aim of this paper is to investigate the ability of GP, which was proposed as an extension of genetic algorithms and was inspired by the Darwinian evolution theory, in the analysis of credit scoring models in Egyptian public sector banks. The secondary aim is to compare GP with probit analysis (PA), a successful alternative to logistic regression, and weight of evidence (WOE) measure, the later a neglected technique in published research. Two evaluation criteria are used in this paper, namely, average correct classification (ACC) rate criterion and estimated misclassification cost (EMC) criterion with different misclassification cost (MC) ratios, in order to evaluate the capabilities of the credit scoring models. Results so far revealed that GP has the highest ACC rate and the lowest EMC. However, surprisingly, there is a clear rule for the WOE measure under EMC with higher MC ratios. In addition, an analysis of the dataset using Kohonen maps is undertaken to provide additional visual insights into cluster groupings. 2009 Elsevier Ltd. All rights reserved.
An open-label pilot study to identify the usefulness of adjuvant homoeopathic medicines in the treatment of cerebral stroke patients

Background: Stroke, the third leading cause for neurological morbidity and mortality has a global annual incidence of 0.2–2.5/1000 population. The clinical sequelae of stroke are often devastating with hemiparesis, depression, walking difficulties and aphasia. It is essential to take measures halting the progression of stroke. Homoeopathic literature mentions many medicines for stroke. Till a pilot study was undertaken to study the usefulness of Homoeopathy as an adjuvant therapy to standard conventional care in stroke patients. Materials and Methods: An open-label pilot study was conducted at Princess Durru Shehvar Children's and General Hospital, Hyderabad, in coordination with Extension Clinical Research Unit of Central Council for Research in Homoeopathy. Fifty patients presenting with episodes of cerebral stroke of the different period were assessed by the National Institute of Health Stroke Scale (NIHSS) Score, prior homoeopathic treatment and after 6 months of treatment. Results: Of 50 patients, 10 patients had stroke more than 1 year and suffering with sequelae, 27 patients had stroke episode between 1 month and 1 year and 13 patients had a stroke episode within 4 weeks. The reduction in NIHSS score after 6 months of treatment was statistically significant in all three groups. The useful medicines found were Causticum ( n = 11), Arnica montana ( n = 7), Nux vomica ( n = 6), Lycopodium ( n = 6) and Lachesis ( n = 3). Neither patient had worsening signs nor any new infarcts during the study. Conclusion: This pilot study showed encouraging results. Further randomised control trials are suggested to evaluate the efficacy of homoeopathic medicines in stroke.
Job characteristics and employee well-being : a test of Warr ' s Vitamin Model in health care workers using structural equation modelling

Warr's (1987) Vitamin Model was investigated in a representative sample of 1437 Dutch health care workers (i.e. nurses and nurses' aides). According to this model, it was hypothesized that three job characteristics (i.e. job demands, job autonomy, and workplace social support) are curvilinearly related with three key indicators of employee well-being (i.e. job satisfaction, job-related anxiety, and emotional exhaustion). Structural equation modelling (LISREL 8) was employed to test the comprehensive Vitamin Model. The results showed that the ®t of the non-linear model is superior to that of the linear model. Except for the relationship between job autonomy and emotional exhaustion, the curvilinear relationships followed the predicted U-shaped or inverted U-shaped curvilinear pattern. Moreover, it appeared that the three job characteristics are dierentially related with various indicators of employee well-being. In conclusion, this study partially supports the assertion of the Vitamin Model that non-linear relationships exist between job characteristics and employee well-being. # 1998 John Wiley & Sons, Ltd.
Efficiency of liquid culture systems over conventional micropropagation: A progress towards commercialization

The most common methods of micropropagation involve the proliferation of shoots via a semi solid system. While such semi solid systems have been moderately to highly successful in terms of multiplication yields, it has become increasingly important to improve productivity and reduce the time taken to multiply commercially important material. Micropropagation by conventional techniques is typically a labor intensive time taking means of clonal propagation. To overcome this, the use of shake cultures utilizing liquid culture medium has been promoted. The liquid medium allows the close contact with the tissue which stimulates and facilitates the uptake of nutrients and phytohormones, leading to better shoot and root growth. Continuous shaking promotes lesser expression of apical dominance which generally leads to induction and proliferation of numerous axillary buds. Further, with in the shake culture conditions, the growth and multiplication rate of shoots is enhanced by forced aeration, since continuous shaking of medium provides ample oxygen supply to the tissue which ultimately leads to their faster growth. Bioreactor provides a rapid and efficient clonal propagation system utilizing liquid medium to avoid intensive manual handling. Automation of micropropagation in bioreactors has been advanced by several authors as a possible way of reducing cost of micropropagation. Micropropagation in bioreactors for optimal plant production depends upon better understanding of physiological and biochemical responses of plant to the signals of culture microenvironment and an optimization of specific physical and chemical culture conditions to control the morphogenesis of plants in liquid culture systems.
Polypropylene based thermoplastic polymers for potential recyclable HVDC cable insulation applications

Thermoplastic materials are highly desirable for power cable insulation application because of their recyclability and ease of processing. They are particularly suitable for high voltage direct current (HVDC) cable insulation because of the absence of byproducts during cable production, which may result in the reduction of undesirable space charge accumulation and the degassing cost. Polypropylene based polymers may have the potential for recyclable thermoplastic cable insulation application because of their high melting temperatures and adjustable mechanical and electrical properties. This work aimed at evaluating the potential of isotactic polypropylenes, propylene-ethylene block copolymers and random copolymers for thermoplastic cable insulation application. We investigated the melting and crystallization behavior, crystal structure, supramolecular structure, mechanical properties, space charge distribution and DC breakdown strength of six different polymers (two isotactic polypropylenes, two block copolymers and two random copolymers). A comprehensive analysis of these parameters indicates that the propylene-ethylene binary random copolymers are more potentially suitable for thermoplastic cable insulation application.
Antioxidant activity and hepatoprotective effects of whey protein and Spirulina in rats.

OBJECTIVES
The aims of the present study were to evaluate the antioxidant, radical scavenging, and metal-chelating activity of whey protein concentrate (WPC) and Spirulina alone or in combination in vitro and to evaluate their hepatoprotective effects against CCl(4) in vivo.


METHODS
Five concentrations (20, 40, 60, 80, and 100 mg/100 mL) of WPC, Spirulina, and their combination were tested in vitro. In the in vivo study, eight groups of male rats comprised the control group and the groups treated with WPC, Spirulina alone, or in combination with or without CCl(4) were used.


RESULTS
The in vitro study showed that WPC and Spirulina showed antioxidant, radical scavenging, and metal-chelating activities in dose-dependent manner. The in vivo study showed that both agents succeeded in preventing liver damage induced by CCl(4). This prevention was more pronounced in rats receiving the combination of WPC and Spirulina.


CONCLUSION
Whey protein concentrate and Spirulina have free radical scavenging properties and antioxidant activity.
Urinary storage symptoms and comorbidities: a prospective population cohort study in middle-aged and older women.

OBJECTIVE
to identify predictive morbidities for urinary storage syndromes including indicators for neurological, musculoskeletal, cardiovascular, immune, lower bowel and psychological systems. This is the first study to test prior hypotheses, based on a literature review.


DESIGN
this was a prospective cohort study involving 12,570 female respondents aged 40 or more registered with general practitioners and living at home in Leicestershire. Postal questionnaires were used at baseline and 1-year follow-up (response rates 65 and 79%, respectively).


MEASURES
pure stress urinary incontinence (SUI) and overactive bladder syndrome (OAB) were defined using standardised symptom indicators. Specific morbidities included reported medical diagnoses, standardised symptoms and general health indicators. Associations were identified using logistic regression, adjusting for age and physical impairment, with separate models for general and specific morbidities.


RESULTS
multivariate morbidities consistently associated (i.e. both longitudinally and cross-sectionally) were SUI-cystitis and obesity; and OAB-bowel urgency, osteoporosis, imbalance, ankle swelling, cystitis, poor health and old age. Other independent predictors were SUI-multiple sclerosis and joint pain; and OAB-deep vein thrombosis and diabetes. Consistent univariate indicators supported neurological, musculoskeletal, cardiovascular, immunological and psychological connections with both types of storage disorder plus an association with lower bowel problems for OAB.


CONCLUSIONS
abnormal urinary storage symptoms were predicted by obesity and poor general health, involving a range of systems of the body. OAB showed more extensive links than SUI with specific morbidities, including more medically diagnosed as opposed to symptom-based conditions. These findings were independent of problems with physical impairment.
Using machine learning to draw inferences from pass location data in soccer

In this paper, we present two approaches to analyzing pass event data to uncover sometimes-nonobvious insights into the game of soccer. We illustrate the utility of our methods by applying them to data from the 2012–2013 La Liga season. We first show that teams are characterized by where on the pitch they attempt passes, and can be identified by their passing styles. Using heatmaps of pass locations as features, we achieved a mean accuracy of 87% in a 20-team classification task. We also investigated using pass locations over the course of a possession to predict shots. For this task, we achieved an area under the receiver operating characteristic (AUROC) of 0.785. Finally, we used the weights of the predictive model to rank players by the value of their passes. Shockingly, Cristiano Ronaldo and Lionel Messi topped the rankings. © 2016 Wiley Periodicals, Inc. Statistical Analysis and Data Mining: The ASA Data Science Journal, 2016
Examining the Effectiveness of Executive Coaching on Coachees' Performance in the Israeli Context

While executive coaching is a key means by which organisations and individuals build executives’ capabilities, very little research has investigated how effective or beneficial this development tool is to the individuals or the organisations in which they work. The purpose of this study was to examine executive coaching effectiveness by investigating whether executive coaching has an impact on coachee performance outcomes as well as individual outcomes as manifested by self awareness, career satisfaction, job affective commitment, and job performance. Coaching outcomes were examined through a quasi-experimental field pre-post design with an untreated control group. The study participants (n=197) were drawn from the client bases of four Israeli-based firms whose primary professional services focused on executive coaching. The primary conclusion is that executive coaching may be a mechanism by which executives could be helped in improving and maintaining a high level of career satisfaction. The results should assist organizations in designing more effective executive coaching programs, and in making informed decisions about implementing and measuring executive coaching.
DC Motor Speed Control using Fuzzy Logic based on LabVIEW

This paper presents implement in speed control of a separately excited DC motor using fuzzy logic control (FLC) based on LabVIEW (Laboratory Virtual Instrument Engineering Workbench) program. LabVIEW, is a graphical programming environment suited for high-level or system-level design. Therefore, the principle that are data flow model, different from text-base programming and a sequential model. The user-friendly interface and toolbox design are shown the high level of suitableness and stability of LabVIEW and fuzzy logic on speed control of DC motor. The fuzzy logic controller designed to applies the required control voltage that sent to DC motor based on fuzzy rule base of motor speed error (e) and change of speed error (ce). The results show the control as a FLC that do the comparison with PI and PID controller
Earnings Management: IPO Valuation and Subsequent Performance:

We examine the role of earnings management by firms prior to making initial public offerings (IPOs). Our results indicate that pre-IPO abnormal accruals are positively related to initial firm value. Entrepreneurs may seek to increase their offering proceeds, temporarily deceiving investors by opportunistically manipulating earnings through accruals management before going public. This would imply a negative relationship between abnormal accruals around the offer date and subsequent firm performance. Confirming earlier studies, we find that abnormal accruals during the offer year are significantly negatively related to subsequent firm stock returns. In addition, we find that abnormal accruals in the preceding year are also significantly negatively related to subsequent performance. Thus, it appears that aggressive pre-IPO earnings management both increases IPO proceeds and decreases subsequent returns to investors. * We thank Gordon Richardson, Rex Thompson, and Jerry Zimmerman for helpful comments. ** Corresponding author. EARNINGS MANAGEMENT: IPO VALUATION and SUBSEQUENT PERFORMANCE ABSTRACT: We examine the role of earnings management by issuers prior to making initial public offerings (IPOs). Our results indicate that pre-IPO abnormal accruals are positively related to initial firm value. Entrepreneurs may seek to increase their offering proceeds, temporarily deceiving investors by opportunistically manipulating earnings through accruals management before going public. This would imply a negative relationship between abnormal accruals around the offer date and subsequent firm performance. Confirming earlier studies, we find that abnormal accruals during the offer year are significantly negatively related to subsequent firm stock returns. In addition, we find that abnormal accruals in the preceding year are also significantly negatively related to subsequent performance. Thus, it appears that aggressive pre-IPO earnings management both increases IPO proceeds and decreases subsequent returns to investors. We examine the role of earnings management by issuers prior to making initial public offerings (IPOs). Our results indicate that pre-IPO abnormal accruals are positively related to initial firm value. Entrepreneurs may seek to increase their offering proceeds, temporarily deceiving investors by opportunistically manipulating earnings through accruals management before going public. This would imply a negative relationship between abnormal accruals around the offer date and subsequent firm performance. Confirming earlier studies, we find that abnormal accruals during the offer year are significantly negatively related to subsequent firm stock returns. In addition, we find that abnormal accruals in the preceding year are also significantly negatively related to subsequent performance. Thus, it appears that aggressive pre-IPO earnings management both increases IPO proceeds and decreases subsequent returns to investors.
Weather forecasting model using Artificial Neural Network

Weather forecasting has become an important field of research in the last few decades. In most of the cases the researcher had attempted to establish a linear relationship between the input weather data and the corresponding target data. But with the discovery of nonlinearity in the nature of weather data, the focus has shifted towards the nonlinear prediction of the weather data. Although, there are many literatures in nonlinear statistics for the weather forecasting, most of them required that the nonlinear model be specified before the estimation is done. But since the weather data is nonlinear and follows a very irregular trend, Artificial Neural Network (ANN) has evolved out to be a better technique to bring out the structural relationship between the various entities. The paper examines the applicability of ANN approach by developing effective and reliable nonlinear predictive models for weather analysis also compare and evaluate the performance of the developed models using different transfer functions, hidden layers and neurons to forecast maximum, temperature for 365 days of the year. © 2011 Published by Elsevier Ltd. Selection and/or peer-review under responsibility of C3IT Keywords-ANN, hidden layer; artificial neurons; MSE; generalization; validation; over-fitting
Sputum cathelicidin, urokinase plasminogen activation system components, and cytokines discriminate cystic fibrosis, COPD, and asthma inflammation.

BACKGROUND
Interest in airways inflammatory disease has increasingly focused on innate immunity. We investigated several components of innate immunity in induced sputum of patients with cystic fibrosis (CF), COPD, and asthma, and healthy control subjects.


METHODS
Twenty eight patients with mild CF lung disease (age > or = 12 years; FEV1, 74 +/- 3% predicted [mean +/- SE]), 74 adults with COPD (FEV1, 55 +/- 2% of predicted), 34 adults with persistent asthma (FEV1, 66 +/- 2% of predicted), and 44 adult control subjects (FEV1, 85 +/- 1% of predicted) were studied while in stable clinical condition. Levels of sputum interleukin (IL)-8, IL-10, interferon (IFN)-gamma, tumor necrosis factor (TNF)-alpha, human cationic antimicrobial protein 18 (CAP18), urokinase-type plasminogen activator (uPA), uPA receptor (uPAR), and plasminogen activator inhibitor (PAI)-1 were determined. Cell sources were investigated by flow cytometry and immunohistochemistry. Spirometry was performed prior to sputum induction.


RESULTS
CF patient sputum showed greatest increase in IL-8 compared to that of patients with COPD and asthma (which were also greater than control subjects), and elevated levels of TNF-alpha and IL-10 compared to other groups. There were no differences in IFN-gamma. CAP18 levels were elevated in CF and COPD patients compared to control subjects, while asthma patients had reduced CAP18 levels. uPA levels were similar but uPAR was elevated in CF and COPD patients more so than in asthma patients, while PAI-1 levels were elevated in all three disease groups. CAP18 localized to neutrophil secondary granules; neutrophils were also sources of IL-8 and PAI-1. CAP18 and PAI-1 negatively correlated with pulmonary function.


CONCLUSION
Induced-sputum innate immune factor levels discriminate inflammatory changes in CF, COPD, and asthma, suggesting potential roles in pathophysiology and as well as providing disease-specific biomarker patterns.