LLukas22/scidocs huggingface dataset:
Blood Flow Restriction Training After Knee Arthroscopy: A Randomized Controlled Pilot Study.

INTRODUCTION
Quadriceps strength after arthroscopic knee procedures is frequently diminished several years postoperation. Blood flow restriction (BFR) training uses partial venous occlusion while performing submaximal exercise to induce muscle hypertrophy and strength improvements. The purpose of this study was to evaluate BFR as a postoperative therapeutic intervention after knee arthroscopy.


METHODS
A randomized controlled pilot study comparing physical therapy with and without BFR after knee arthroscopy was conducted. Patients underwent 12 sessions of supervised physical therapy. Subjects followed the same postoperative protocol with the addition of 3 additional BFR exercises. Outcome measures included thigh girth, physical function measures, Knee Osteoarthritis Outcome Score (KOOS), Veterans RAND 12-Item Health Survey (VR12), and strength testing. Bilateral duplex ultrasonography was used to evaluate for deep venous thrombosis preintervention and postintervention.


RESULTS
Seventeen patients completed the study. Significant increases in thigh girth were observed in the BFR group at 6-cm and 16-cm proximal to the patella (P = 0.0111 and 0.0001). All physical outcome measures significantly improved in the BFR group, and the timed stair ascent improvements were greater than conventional therapy (P = 0.0281). The VR-12 and KOOS subscales significantly improved in the BFR group, and greater improvement was seen in VR-12 mental component score (P = 0.0149). The BFR group displayed approximately 2-fold greater improvements in extension and flexion strength compared with conventional therapy (74.59% vs 33.5%, P = 0.034). No adverse events were observed during the study.


CONCLUSIONS
This study suggests that BFR is an effective intervention after knee arthroscopy. Further investigation is warranted to elucidate the benefits of this intervention in populations with greater initial impairment.
Big Data security and privacy: A review

While Big Data gradually become a hot topic of research and business and has been everywhere used in many industries, Big Data security and privacy has been increasingly concerned. However, there is an obvious contradiction between Big Data security and privacy and the widespread use of Big Data. In this paper, we firstly reviewed the enormous benefits and challenges of security and privacy in Big Data. Then, we present some possible methods and techniques to ensure Big Data security and privacy.
Rule Based Metadata Extraction Framework from Academic Articles

Metadata of scientific articles such as title, abstract, keywords or
Preconception diet or exercise intervention in obese fathers normalizes sperm microRNA profile and metabolic syndrome in female offspring.

Obesity and type 2 diabetes are increasingly prevalent across all demographics. Paternal obesity in humans and rodents can program obesity and impair insulin sensitivity in female offspring. It remains to be determined whether these perturbed offspring phenotypes can be improved through targeted lifestyle interventions in the obese father. Using a mouse model, we demonstrate that diet or exercise interventions for 8 wk (2 rounds of spermatogenesis) in obese founder males restores insulin sensitivity and normalized adiposity in female offspring. Founder diet and/or exercise also normalizes abundance of X-linked sperm microRNAs that target genes regulating cell cycle and apoptosis, pathways central to oocyte and early embryogenesis. Additionally, obesity-associated comorbidities, including inflammation, glucose intolerance, stress, and hypercholesterolemia, were good predictors for sperm microRNA abundance and offspring phenotypes. Interventions aimed at improving paternal metabolic health during specific windows prior to conception can partially normalize aberrant epigenetic signals in sperm and improve the metabolic health of female offspring.
QoF: Towards Comprehensive Path Quality Measurement in Wireless Sensor Networks

Due to its large scale and constrained communication radius, a wireless sensor network mostly relies on multi-hop transmissions to deliver a data packet along a sequence of nodes. It is of essential importance to measure the forwarding quality of multi-hop paths and such information shall be utilized in designing efficient routing strategies. Existing metrics like ETX, ETF mainly focus on quantifying the link performance in between the nodes while overlooking the forwarding capabilities inside the sensor nodes. The experience on manipulating GreenOrbs, a large-scale sensor network with 330 nodes, reveals that the quality of forwarding inside each sensor node is at the least an equally important factor that contributes to the path quality in data delivery. In this paper we propose QoF, Quality of Forwarding, a new metric which explores the performance in the gray zone inside a node left unattended in previous studies. By combining the QoF measurements within a node and over a link, we are able to comprehensively measure the intact path quality in designing efficient multi-hop routing protocols. We implement QoF and build a modified Collection Tree Protocol (CTP). We evaluate the data collection performance in a testbed consisting of 50 TelosB nodes, and compare it with the original CTP protocol. The experimental results show that our approach takes both transmission cost and forwarding reliability into consideration, thus achieving a high throughput for data collection.
Use of Collagen Matrix for Augmentation of the Peri-implant Soft Tissue at the Time of Immediate Implant Placement.

AIM
The aim of this study was to determine the treatment outcome of the use of a porcine monolayer collagen matrix (mCM) to augment peri-implant soft tissue in conjunction with immediate implant placement as an alternative to patient's own connective tissue.


MATERIALS AND METHODS
A total of 27 implants were placed immediately in 27 patients (14 males and 13 females, with a mean age of 52.2 years) with simultaneous augmentation of the soft tissue by the use of a mCM. The patients were randomly divided into two groups: Group I: An envelope flap was created and mCM was left coronally uncovered, and group II: A coronally repositioned flap was created and the mCM was covered by the mucosa. Soft-tissue thickness (STTh) was measured at the time of surgery (T0) and 6 months postoperatively (T1) using a customized stent. Cone beam computed tomographies (CBCTs) were taken from 12 representative cases at T1. A stringent plaque control regimen was enforced in all the patients during the 6-month observation period.


RESULTS
Mean STTh change was similar in both groups (0.7 ± 0.2 and 0.7 ± 0.1 mm in groups I and II respectively). The comparison of STTh between T0 and T1 showed a statistically significant increase of soft tissue in both groups I and II as well as in the total examined population (p < 0.001). The STTh change as well as matrix thickness loss were comparable in both groups (p > 0.05). The evaluation of the CBCTs did not show any signs of resorption of the buccal bone plate.


CONCLUSION
Within the limitations of this study, it could be concluded that the collagen matrix used in conjunction with immediate implant placement leads to an increased thickness of peri-implant soft tissue independent of the flap creation technique and could be an alternative to connective tissue graft.


CLINICAL SIGNIFICANCE
The collagen matrix used seems to be a good alternative to patient's own connective tissue and could be used for the soft tissue augmentation around dental implants.
Local Learning to Improve Bag of Visual Words Model for Facial Expression Recognition

In this paper we propose a novel computer vision method for classifying human facial expression from low resolution images. Our method uses the bag of words representation. It extracts dense SIFT descriptors either from the whole image or from a spatial pyramid that divides the image into increasingly fine sub-regions. Then, it represents images as normalized (spatial) presence vectors of visual words from a codebook obtained through clustering image descriptors. Linear kernels are built for several choices of spatial presence vectors, and combined into weighted sums for multiple kernel learning (MKL). For machine learning, the method makes use of multi-class one-versus-all SVM on the MKL kernel computed using this representation, but with an important twist, the learning is local, as opposed to global – in the sense that, for each face with an unknown label, a set of neighbors is selected to build a local classification model, which is eventually used to classify only that particular face. Empirical results indicate that the use of presence vectors, local learning and spatial information improve recognition performance together by more than 5%. Finally, the proposed model ranked fourth in the Facial Expression Recognition Challenge, with an accuracy of 67.484% on the final test set. ICML 2013 Workshop on Representation Learning, Atlanta, Georgia, USA, 2013. Copyright 2013 by the author(s).
Association Between Statin Use After Diagnosis of Esophageal Cancer and Survival: A Population-Based Cohort Study.

BACKGROUND & AIMS
Statins (3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors), commonly prescribed in the primary and secondary prevention of cardiovascular disease, promote apoptosis and limit proliferation of esophageal cancer cell lines. We investigated whether statin use after a diagnosis of esophageal cancer is associated with reduced esophageal cancer-specific and all-cause mortality.


METHODS
We identified a cohort of 4445 men and women in the United Kingdom diagnosed with esophageal cancer from January 2000 through November 2009 using the General Practice Research Database. The National Cancer Registry and Office of National Statistics datasets established the histologic subtype and cancer-specific mortality, respectively. Cox proportional hazard regression analysis with time-dependent exposures estimated the association between statin use after diagnosis and esophageal cancer-specific and all-cause mortality.


RESULTS
The median survival time of the entire cohort was 9.2 months (interquartile range [IQR], 3.7-23.2 mo). Among subjects who used statins after a diagnosis of esophageal cancer, the median survival time was 14.9 months (IQR, 7.1-52.3 mo) compared with 8.1 months for nonusers (IQR, 3.3-20 mo). In the entire cohort, statin use after diagnosis was associated with a decreased risk of esophageal cancer-specific mortality (adjusted hazard ratio [HR], 0.62; 95% confidence interval [CI], 0.44-0.86) and all-cause mortality (HR, 0.67; 95% CI, 0.58-0.77). In patients with esophageal adenocarcinoma, statin use after diagnosis was associated with a decreased risk of esophageal cancer-specific mortality (HR, 0.61; 95% CI 0.38-0.96) and all-cause mortality (HR, 0.63; 95% 0.43-0.92). This effect was not observed in patients with esophageal squamous cell carcinoma. There was no evidence for effect modification of these associations with statin use before the cancer diagnosis.


CONCLUSIONS
In a large population-based cohort, statin use after a diagnosis of esophageal adenocarcinoma, but not esophageal squamous cell carcinoma, was associated with reduced esophageal cancer-specific and all-cause mortality.
Pattern recognition-a technique for induction machines rotor fault detection "eccentricity and broken bar fault"

A pattern recognition technique based on Bayes minimum error classifier is developed to detect broken rotor bar faults and static eccentricity in induction motors at the steady state. The proposed algorithm uses stator currents as input without any other sensors. First, rotor speed is estimated from stator currents, then appropriate features are extracted. The produced feature vector is normalized and fed to the trained Bayes minimum error classifier to determine if motor is healthy or has incipient faults (broken bar fault, static eccentricity or both). Only number of poles and rotor slots are needed as pre-knowledge information. Theoretical approach together with experimental results derived from a 3 hp AC induction motor show the strength of this method. In order to cover many different motor load conditions data are derived from 10% to 130% of the rated load for both a healthy induction motor and an induction motor with a rotor having 4 broken bars and/or static eccentricity.
Effect of propolis on proliferation and apoptosis of periodontal ligament fibroblasts.

The most critical factors affecting the prognosis of an avulsed tooth are extraoral dry time and storage media used before replantation. Studies have analyzed different storage media to determine the ideal solution to preserve periodontal ligament (PDL) cell viability. Propolis has anti-inflammatory and antimicrobial properties, and has been previously suggested as a storage medium. The purpose of this study was to assess not only cell viability but also physiological health of PDL cells after exposure to propolis. PDL cells were exposed to different concentrations of propolis or Hanks balanced salt solution, and the apoptotic levels were determined using apoptosis assay and flow cytometry. Additional cell viability and proliferation were analyzed by XXT assay in dry and wet conditions. Propolis not only decreased apoptosis but also increased the metabolic activity and proliferation of PDL cells. This study suggests that propolis is a suitable storage medium for avulsed teeth.
Clinical Management of Neuroleptic Malignant Syndrome

Neuroleptic malignant syndrome (NMS) continues to be an unpredictable and rare, but potentially fatal complication of antipsychotic medications. Presumptively linked to dopamine blockade, it nonetheless occurs in patients receiving newer atypical antipsychotics. The features of NMS, its pathophysiology, differential diagnosis, clinical course, risk factors, and morbidity and motality are reviewed. Nonpharmacologic management centers on aggressive supportive care including vigilant nursing, physical therapy, cooling, rehydration, anticoagulation. Pharmacologic interventions include immediate discontinuation of antipsychotics, judicious use of anticholinergics, and adjunctive benzodiazepines. The utility of specific agents in actively treating NMS is reviewed. Bromocriptine and other dopaminergic drugs and dantrolene sodium have alternatively been considered without merit or efficacious. Guidelines for using these agents are presented. Electroconvulsive therapy, also somewhat controversial, is identified as a second line of treatment. Finally, management of the post-NMS patient is also reviewed.
Reduction of arterial pressure and double product at rest after resistance exercise training in elderly hypertensive women.

BACKGROUND
Due to the existing controversies in literature about the potential benefits of resistance exercise training (RT) on arterial blood pressure (BP) at rest, and the lack of studies conducted with elderly hypertensive individuals, RT is seldom recommended as a non-pharmacological treatment for arterial hypertension.


OBJECTIVE
To verify the effect of progressive RT on BP, HR, and RPP in elderly women with controlled hypertension.


METHODS
20 elderly women (66.8 +/- 5.6 years of age), with a sedentary lifestyle, monitored with anti-hypertensive medication, participated in a 12-week RT program (resistance training group - RTG). Twenty-six elderly women (65.3 +/- 3.4 years of age) with controlled hypertension did not engage in physical exercise during the study period, and composed the control group.


RESULTS
After RT, there was a significant reduction in SBP, MBP, and DP values at rest. No significant drops in DBP and HR values at rest were observed after RT in both groups. The reduction in the RTG was 10.5 mmHg, 6.2 mmHg, and 2218.6 mmHg x bpm for SBP, MBP, and RPP, respectively.


CONCLUSION
Progressive RT reduced SBP, MBP, and RPP values at rest of hypertensive elderly women who were on anti-hypertensive treatment.
Middle Miocene volcanism in the vicinity of the Middle Hungarian zone: Evidence for an inherited enriched mantle source

Abstract Middle Miocene igneous rocks in the vicinity of the Middle Hungarian zone (MHZ) show a number of subduction-related geochemical characteristics. Many of these characteristics appear to be time-integrated, showing a decreasing subduction signature with time. In contrast to previous models, which suggest southward-dipping subduction of European lithosphere beneath the Alcapa microplate (along the Western Carpathians) is responsible for the chemical characteristics seen in middle Miocene volcanics, we propose that source enrichment occurred via the subduction of either the Budva-Pindos or Vardar Oceans. Recent seismic studies have revealed that the proposed southward-dipping subduction was not developed beneath the entire Western Carpathians or, even if it had, was overprinted by the collision of the European plate and the Alcapa unit at 16 Ma. This subduction is thought to have started 30 Ma ago, therefore the time between the onset of subduction and collision cannot account for extensive source enrichment in the overlying mantle wedge. It is also pertinent to note that the middle Miocene igneous rocks of the MHZ in their reconstructed positions are not parallel to the supposed suture expected for subduction-related arc volcanoes. Our review suggests an alternative hypothesis, whereby source enrichment is related to the subduction of either the Budva-Pindos or Vardar Ocean during the Mesozoic–Paleogene. In this model the Alcapa microplate was transferred to its present tectonic position via extrusion and rotations. Geophysical modeling and mantle xenoliths provide evidence that this process occurred at the scale of the lithospheric mantle, indicating that the subduction-modified lithospheric mantle was coupled to the crust. Melting in the lithospheric mantle of the Alcapa unit was triggered by the extension during the formation of the Pannonian Basin. The preserved subduction-related geochemical character of volcanics in intra-plate settings that are otherwise directly unaffected by subduction, can be attributed to tectonic transport of metasomatised mantle from a previous subduction-affected setting. This model provides an alternative approach to understanding the geochemical complexity seen among intra-plate calc-alkaline volcanics, where chemical characteristics can be explained without the involvement of plumes.
Effect of n-3 supplementation on hyperactivity, oxidative stress and inflammatory mediators in children with attention-deficit-hyperactivity disorder.

BACKGROUND
Attention-deficit/hyperactivity disorder (ADHD) is associated with difficulties in learning, behaviour and psychosocial adjustment that persist into adulthood. Decreased omega-3 fatty acids and increased inflammation or oxidative stress may contribute to neuro-developmental and psychiatric disorders such as ADHD. The aim of this study was to determine the effect of n-3 supplementation on hyperactivity, oxidative stress and inflammatory mediators in children with ADHD.


METHODS
In this double blind study, 103 children (6-12 years) with ADHD receiving maintenance therapy were assigned randomly into two groups. The n-3 group received n-3 fatty acids (635 mg eicosapentaenoic acid (EPA), 195 mg docosahexaenoic acid (DHA)), and the placebo group received olive oil capsules which were visually similar to the n-3 capsules. The duration of supplementation was 8 weeks. Plasma C-reactive protein (CRP), interleukin-6 (IL-6) and the activity of glutathione reductase (GR), catalase (CAT) and superoxide dismutase (SOD) were determined before and after the intervention. Likewise the Conners' Abbreviated Questionnaires (ASQ-P) was applied.


RESULTS
After 8-week intervention, a significant reduction was observed in the levels of CRP ( P < 0.05, 95% CI = 0.72-2.02) and IL-6 (P < 0.001, 95% CI = 1.93-24.33) in the n-3 group. There was also a significant increase in activity of SOD and GR (P < 0.001). A significant improvement was seen in the ASQ-P scores in the n-3 group (P < 005).


CONCLUSION
Eight weeks of EPA and DHA supplementation decreased plasma inflammatory mediators and oxidative stress in the children with ADHD. These results suggest that n-3 fatty acid supplementation may offer a safe and efficacious treatment for children with ADHD.
No effect of preterm birth on the risk of multiple sclerosis: a population based study

BACKGROUND
Genetic and environmental factors have important roles in multiple sclerosis (MS) susceptibility. A clear parent of origin effect has been shown in several populations, perhaps resulting from factors operating during gestation. Preterm birth (birth at less than 37 weeks gestational age) has been shown to result in long-term health problems, including impaired neurological development. Here, in a population-based cohort, we investigate whether preterm birth increases the risk to subsequently develop MS.


METHODS
We identified 6585 MS index cases and 2509 spousal controls with preterm birth information from the Canadian Collaborative Project on Genetic Susceptibility to MS. Rates of individuals born preterm were compared for index cases and controls.


RESULTS
There were no significant differences between cases and controls with respect to preterm births. 370 (5.6%) MS index cases and 130 (5.2%) spousal controls were born preterm, p = 0.41.


CONCLUSION
Preterm birth does not appear to contribute to MS aetiology. Other factors involved in foetal and early development need to be explored to elucidate the mechanism of the increased risk conferred by the apparent maternal effect.
Luc's Abscess: A reminder of a potential complication of otitis media

Otitis media is still a common infection and can be associated with complications if not treated early. We report the case of an elderly gentleman who presented with an abscess deep to the temporalis muscle ‘Luc’s abscess’, as a complication of otitis media. Henry Luc first described this condition a century ago and in the antibiotic era, such manifestation is now rarely seen. We report the case of a 73year-old man diagnosed with Luc’s abscess who presented with a week’s history of right temporal swelling that was associated with fever, right ear pain and progressive hearing impairment. This case report is a reminder to clinicians of this rare but treatable complication of a very common disease in the community.
An experimental overview of results presented at SQM 2006

I discuss experimental results presented at Strange Quark Matter 2006 and their implications concentrating primarily on RHIC data.