LLukas22/scidocs huggingface dataset:
HMM-Based Speech Synthesis with Various Speaking Styles Using Model Interpolation

This paper presents an approach to realizing various speaking styles and emotional expressions using a model interpolation technique in HMM-based speech synthesis. In the approach, we synthesize speech with an intermediate speaking style between representative speaking styles from a model obtained by interpolating representative style models. We chose three styles, “reading,” “joyful,” and “sad,” as representative styles, and synthesized speech from models obtained by interpolating two models for every combination of two styles. From a result of a subjective similarity evaluation, it is shown that speech generated from an interpolated model has a speaking style in between two representative speaking styles.
A phase I study of decitabine and rapamycin in relapsed/refractory AML.

A phase I study utilizing decitabine (DAC) followed by the mammalian target of rapamycin (mTOR) inhibitor, rapamycin, in patients with relapsed/refractory adult AML was undertaken to assess safety and feasibility. Patients received DAC 20mg/m(2) intravenously daily for 5 days followed by rapamycin from day 6 to day 25 at doses of 2 mg, 4 mg, and 6 mg/day in a standard 3+3 dose escalation design. Twelve patients completed treatment for safety evaluation. Maximum tolerated dose (MTD) was not reached, and except for grade 3 mucositis in 4 patients, no other significant unexpected non-hematologic toxicities have occurred indicating safety of this regimen. This trial is registered at clinical trials.gov as NCT00861874.
Robust Speed Control of an Induction Motor Drive using Wavelet-fuzzy based Self-tuning Multiresolution Controller

This paper presents a hybrid wavelet-fuzzy based multiresolution (MR) controller for robust speed control of induction motor. The discrete wavelet transform (DWT) is used to decompose the error between the actual speed and command speed of the induction motor drive in to different frequency components. A self-tuning fuzzy logic is used for online tuning of the controller parameters. The proposed controller has the ability of meeting the speed tracking requirements in the closed loop system. The complete indirect field oriented control scheme incorporating the proposed wavelet-fuzzy based MR controller is investigated theoretically and simulated under various dynamic operating conditions. Simulation results are compared with that of conventional PI controller and fuzzy based PI controller. The speed control scheme incorporating the proposed controller is implemented in real time using the digital processor (DSP) control board. Simulation and experimental results validates the effectiveness of the proposed controller over conventional controllers and proves to be more suitable for high performance applications.
ISOGAT: A 2D tutorial MATLAB code for Isogeometric Analysis

Article history: Available online 18 June 2010
Ionizing radiation effects on food vitamins: a review

Ionizing radiation has been widely used in industri al processes, especially in the sterilization of me dicals, pharmaceuticals, cosmetic products, and in food pro cessing. Similar to other techniques of food proces sing, irradiation can induce certain alterations that can modify both the chemical composition and the nutri tional value of foods. These changes depend on the food composit ion, the irradiation dose and factors such as tempe rature and presence or absence of oxygen in the irradiating en viro ment. The sensitivity of vitamins to radiation is unpredictable and food vitamin losses during the ir radiation are often substantial. The aim of this st udy was to discuss retention or loss of vitamins in several fo od products submitted to an irradiation process.
Proof theory for locally finite many-valued logics: Semi-projective logics

We extend the methodology in Baaz and Fermüller (1999) [5] to systematically construct analytic calculi for semi-projective logics-a large family of (propositional) locally finite many-valued logics. Our calculi, defined in the framework of sequents of relations, are proof search oriented and can be used to settle the computational complexity of the formalized logics. As a case study we derive sequent calculi of relations for Nilpotent Minimum logic and for Hajek's Basic Logic extended with the [Formula: see text]-contraction axiom ([Formula: see text]). The introduced calculi are used to prove that the decidability problem in these logics is Co-NP complete.
Stress coupling between earthquakes in northwest Turkey and the north Aegean Sea

We have investigated the Coulomb stress interactions of 29 earthquakes (Ms ≥ 6.0) that have occurred in the region of northwest Turkey and north Aegean Sea since 1912. Of these events, 23 may be related to earlier events, and 16 are clearly related to earlier events. All events after 1967 are related to previous events. Events in the early part of our time interval that show no correlation could be related to historical events as yet unidentified. In some cases, faults that have received a stress reduction from earlier events are prepared for an event by an earthquake occurring a few years before that creates a local Coulomb stress rise. Thus regions of Coulomb stress shadow can become regions where a damaging earthquake may occur. The relation between smaller events and the Coulomb stress distribution is less clear, but may be related to poor data quality and practical limitations of our modeling technique. Nonetheless, there are 4 times as many events per unit area in regions of enhanced stress than where stress is reduced. We discuss the contemporary distribution of Coulomb stress and argue that it is possible to identify the likely locations of future damaging earthquakes including identifying the most likely candidate faults.
2012-2013 Seasonal Influenza Vaccine Effectiveness against Influenza Hospitalizations: Results from the Global Influenza Hospital Surveillance Network

BACKGROUND
The effectiveness of currently licensed vaccines against influenza has not been clearly established, especially among individuals at increased risk for complications from influenza. We used a test-negative approach to estimate influenza vaccine effectiveness (IVE) against hospitalization with laboratory-confirmed influenza based on data collected from the Global Influenza Hospital Surveillance Network (GIHSN).


METHODS AND FINDINGS
This was a multi-center, prospective, active surveillance, hospital-based epidemiological study during the 2012-2013 influenza season. Data were collected from hospitals participating in the GIHSN, including five in Spain, five in France, and four in the Russian Federation. Influenza was confirmed by reverse transcription-polymerase chain reaction. IVE against hospitalization for laboratory-confirmed influenza was estimated for adult patients targeted for vaccination and who were swabbed within 7 days of symptom onset. The overall adjusted IVE was 33% (95% confidence interval [CI], 11% to 49%). Point estimates of IVE were 23% (95% CI, -26% to 53%) for influenza A(H1N1)pdm09, 30% (95% CI, -37% to 64%) for influenza A(H3N2), and 43% (95% CI, 17% to 60%) for influenza B/Yamagata. IVE estimates were similar in subjects <65 and ≥65 years of age (35% [95% CI, -15% to 63%] vs.31% [95% CI, 4% to 51%]). Heterogeneity in site-specific IVE estimates was high (I2 = 63.4%) for A(H1N1)pdm09 in patients ≥65 years of age. IVE estimates for influenza B/Yamagata were homogenous (I2 = 0.0%).


CONCLUSIONS
These results, which were based on data collected from the GIHSN during the 2012-2013 influenza season, showed that influenza vaccines provided low to moderate protection against hospital admission with laboratory-confirmed influenza in adults targeted for influenza vaccination. In this population, IVE estimates against A(H1N1)pdm09 were sensitive to age group and study site. Influenza vaccination was moderately effective in preventing admissions with influenza B/Yamagata for all sites and age groups.
Complex traditional Chinese medicine for poststroke motor dysfunction: a systematic review.

BACKGROUND AND PURPOSE
For its current dimensions, stroke represents the world's primary health challenge. In China stroke is the second most common cause of death. Traditional Chinese Medicine (TCM) has for many centuries been used, and it is still widely used today in countries of south and east Asia for the treatment of people with stroke. The objective of this systematic review was to evaluate whether complex Traditional Chinese Medicine (cTCM) improves poststroke motor recovery. In particular, we defined cTCM as intervention that included at least acupuncture and Chinese herbal medicine.


METHODS
An extensive search including PubMed, EMBASE, CBM, and the Cochrane Library was performed up to December 2007. Randomized clinical trials (RCTs) about cTCM for motor dysfunction of poststroke were searched irrespective of any language. The quality of each trial was assessed according to the Cochrane Reviewers' Handbook 4.2.6.


RESULTS
After selection of 11 234 articles, 34 RCTs and quasi-RCTs were included. All these trials were conducted in China and published on Chinese journals. All trials but one reported results in favor of cTCM treatments suggesting a strong publication bias. Because of the significant clinical and methodological heterogeneity, no meta-analysis was performed and thus no cumulative result was obtained pooling data of RCTs.


CONCLUSIONS
What appears from this systematic review is that scant data are available to evaluate efficacy of cTCM for poststroke motor dysfunction. Most of the primary studies available for this review were inadequately designed trials characterized by unknown dropout rates and definitional vagueness in outcomes measures. None of the studies approached important end points like death, survival times, rate of dependency, reduction in length of stay in hospital, etc. The key to lead to evidence-based practices is establishing a consensus on standardized relevant outcome measures and then designing and conducting appropriate RCTs that adopt those standards.
Efficacy and safety of once daily triamcinolone acetonide aqueous nasal spray in adults with non-allergic and allergic rhinitis.

BACKGROUND
The efficacy of corticosteroid has not been thoroughly studied in the treatment of non-allergic rhinitis. This study was designed to compare the efficacy of nasal corticosteroid in patients with allergic rhinitis (AR), and non-allergic rhinitis (NAR).


METHODS
The efficacy of triamcinolone acetonide nasal spray (TANS) on total nasal symptom scores (TNSS), and nasal peak inspiratory flow rate (nPIFR) was studied in a six-week parallel-group trial of NAR (n: 25), and AR (n: 16) patients. Health-related quality of life (HRQoL) and Epworth Sleepiness Scale (ESS) were also analysed.


RESULTS
The TNSSs, and symptom scores of conjunctivitis, snoring, and postnasal drainage were significantly improved in both groups, after two and six weeks of treatment. In contrast to AR, patients with NAR had statistically significant improvement in nasal obstruction, and postnasal drainage beginning from two weeks of the treatment. nPIFR slightly increased in both groups. Scores of generic (SF-36), rhinitis specific (MiniRQLQ) and ESS questionnaires generally improved better in AR than NAR. TANS was well-tolerated in AR and NAR groups with minor adverse events including headache, nasal burning, and bitter mouth taste.


CONCLUSIONS
Our study disproved the idea of ineffectiveness of corticosteroid treatment in NAR, and showed that triamcinolone acetate may be an alternative drug in the treatment of NAR.
A dissimilarity measure for the k-Modes clustering algorithm

Clustering is one of the most important data mining techniques that partitions data according to some similarity criterion. The problems of clustering categorical data have attracted much attention from the data mining research community recently. As the extension of the k-Means algorithm, the k-Modes algorithm has been widely applied to categorical data clustering by replacing means with modes. In this paper, the limitations of the simple matching dissimilarity measure and Ng’s dissimilarity measure are analyzed using some illustrative examples. Based on the idea of biological and genetic taxonomy and rough membership function, a new dissimilarity measure for the k-Modes algorithm is defined. A distinct characteristic of the new dissimilarity measure is to take account of the distribution of attribute values on the whole universe. A convergence study and time complexity of the k-Modes algorithm based on new dissimilarity measure indicates that it can be effectively used for large data sets. The results of comparative experiments on synthetic data sets and five real data sets from UCI show the effectiveness of the new dissimilarity measure, especially on data sets with biological and genetic taxonomy information. 2011 Elsevier B.V. All rights reserved.
Governance of Innovation and Intermediation in Triple Helix Interactions

Research on sustainability and innovation-driven economic growth has exposed the lack of sufficient knowledge within the governance literature that can support and justify the extent of government involvement. This paper focuses on the governance of innovation and the intermediary role of the state. We synthesise the literature on governance and regulation and introduce the concept of intermediation in the innovation process. The paper employs the Triple Helix model that describes interactions and intermediation between government, industry and universities and extends this model by looking at the role played by intermediaries and among them public and private institutions, government bodies and independent organisations. We develop a new theoretical framework for the analysis of intermediation and governance of innovation and apply this to four case studies of intermediaries in the health technology cluster in the Greater South East region in the UK. Our empirical findings demonstrate the heuristics of the intermediation concept and the application of our Intermediation framework.
The effects of androgen administration on phallic androgen receptor expression.

PURPOSE
Whether androgens down regulate the androgen receptor during penile development is controversial. We investigated the effects of androgens on penile androgen receptor expression.


MATERIALS AND METHODS
We injected prepubertal hypogonadotropic hypogonadal microphallic rats with testosterone or dihydrotestosterone. Specimens were obtained at 3 (prepuberty), 9 (puberty to early postpuberty) and 12 weeks (late postpuberty). At necropsy we compared penile size and androgen receptor expression of these animals to those of age matched nontreated hypogonadotropic hypogonadal and normal controls.


RESULTS
At age 3 weeks prepubertal androgens up regulated androgen receptor expression and significantly increased penile size compared to normal and untreated hypogonadotropic hypogonadal controls. By 9 weeks the normal down regulation of androgen receptor that occurs with maturation was present. Prepubertal androgens failed to accelerate or exaggerate the normal maturational loss of the androgen receptor. At 9 weeks penile size of normal controls and prepubertal androgen treated animals was identical. Interestingly despite down regulation of the penile androgen receptor, normal animals continued to have increases in penile size between 9 and 12 weeks, while the prepubertal androgen treated animals had no penile growth.


CONCLUSIONS
Prepubertal androgen administration in hypogonadotropic hypogonadal animals resulted in diminutive penises in adulthood. However, the decrease in penile size was not associated with an accelerated or exaggerated down regulation of the androgen receptor. This finding coupled with continued growth of the normal control penises after androgen receptor down regulation suggests that cessation of penile growth may not be solely related to down regulation of the penile androgen receptor.
IMAGE ENCRYPTION AND DECRYPTION USING BLOWFISH ALGORITHM IN MATLAB

With the progress in data exchange by electronic system, the need of information security has become a necessity. Due to growth of multimedia application, security becomes an important issue of communication and storage of images. This paper is about encryption and decryption of images using a secret-key block cipher called 64-bits Blowfish designed to increase security and to improve performance. This algorithm will be used as a variable key size up to 448 bits. It employs Feistel network which iterates simple function 16 times. The blowfish algorithm is safe against unauthorized attack and runs faster than the popular existing algorithms. The proposed algorithm is designed and realized using MATLAB.
Sonographic features of benign intraperitoneal lipomatous tumors in children-report of 4 cases

Four children with benign intraperitoneal lipomatous tumors (mesenteric lipoma, mesenteric lipoblastoma, omental lipoblastoma and mesenteric mesenchymoma) are reported. The ultrasonographic findings of these unusual pediatric masses are described and correlated with their conventional radiologic and pathologic appearance. The pre-operative diagnosis of these entities can be suggested by these features.
Phase-shift and amplitude control for an active rectifier to maximize the efficiency and extracted power of a Wireless Power Transfer system

Wireless Power Transfer (WPT) is an emerging technology with a huge variety of possible applications, including wireless charging of mobile devices like smart-phones or tablet computers. Currently available systems targeting these applications achieve a relatively low efficiency and hence a limited charging capability. To overcome these drawbacks, this work proposes a concept to maximize the efficiency of a WPT system as well as to increase the amount of extracted power. The presented method is based on actively modifying the equivalent secondary-side load impedance by controlling the phase-shift of the active rectifier and its output voltage level. The proposed concept enables WPT systems to actively adjust both the resistive as well as the reactive part of the equivalent load impedance, hence increasing the system performance in terms of efficiency and extracted power. A prototyping system for mobile applications has been developed based on the Qi standard specifications. The acquired experimental results confirm that the proposed concept is able to obtain a higher system efficiency and to extract more power than state-of-the-art solutions.
The Multilayer Firewall

We present a new security technology called the Multilayer Firewall. We argue that it is useful in some situations for which other approaches, such as cryptographically protected communications, present operational or economic difficulties. In other circumstances a Multilayer Firewall can compliment such security technology by providing additional protection against intruder attacks. We first present the operational theory behind the Multilayer Firewall and then describe a prototype that we designed and
Using natural language processing technology for qualitative data analysis

Social researchers often apply qualitative research methods to study groups and their communications artefacts. The use of computer-mediated communications has dramatically increased the volume of text available, but coding such text requires considerable manual effort. We discuss how systems that process text in human languages (i.e., natural language processing, NLP) might partially automate content analysis by extracting theoretical evidence. We present a case study of the use of NLP for qualitative analysis in which the NLP rules showed good performance on a number of codes. With the current level of performance, use of an NLP system could reduce the amount of text to be examined by a human coder by an order of magnitude or more, potentially increasing the speed of coding by a comparable degree. The paper is significant as it is one of the first to demonstrate the use of high-level NLP techniques for qualitative data analysis. (150 words)
Epidemiological characteristics and causes of deaths in hospitalized patients under intensive care.

Objective: to describe the epidemiological and sociodemographic characteristics of patients hospitalized in an ICU. Method: an epidemiological, descriptive and retrospective study. Population: 695 patients admitted from January to December 2011. The data collected were statistically analyzed with both absolute and relative frequency distribution. Results: 61.6% of the patients are male, aged 40 to 69 years, and most of them came from the surgery rooms. The most frequent reason for admission was diseases of the circulatory system (23.3%). At discharge from the ICU, 72.4% of the patients were sent to other units of the same institution, 31.1% to the intermediate care unit, and 20.4% died, of which 24.6% from diseases of the circulatory system. The afternoon shift had 45.8% of the admissions and 53.3% of the discharges. Conclusion: the description of the sociodemographic and epidemiological features guides the planning of nursing actions, providing a better quality service.
Antiviral activity and safety of LB80380 in hepatitis B e antigen-positive chronic hepatitis B patients with lamivudine-resistant disease.

UNLABELLED
We aimed to determine the antiviral activity and safety of a new nucleotide analogue, LB80380, in chronic hepatitis B (CHB) patients with lamivudine-resistant virus. Sixty-five patients with lamivudine-resistant virus were randomized to receive five ascending daily doses (30, 60, 90, 150, 240 mg) of LB80380. LB80380 was given together with lamivudine for the first 4 weeks, followed by 8 weeks of LB80380 monotherapy. This was then followed by 24 weeks of adefovir. Hepatitis B virus (HBV) DNA levels, serology, liver biochemistry, and safety were monitored. The extent of the HBV DNA reduction at week 12 was dose-dependent. The mean reduction from baseline was 2.81, 3.21, 3.92, 4.16, and 4.00 log(10) copies/mL for the five ascending dose groups. The dose-proportionate effect was statistically significant (P < 0.001) with a decrease of HBV DNA levels by an average of 1.54 log(10) copies/mL for every 1-unit increase in log(10) dose of LB80380. In 93.4% of patients, HBV DNA decreased by >2 log(10) copies/mL, and 11.5% of patients had undetectable HBV DNA levels (<300 copies/mL) by week 12. HBV DNA suppression was maintained during the 24 weeks of adefovir treatment. Hepatitis B e antigen seroconversion and normalization of alanine aminotransferase were seen in 14.6% and 24.6% of patients, respectively, at week 12; 44.6% of patients experienced mild and self-limiting adverse events, none of which were attributed to the study drug.


CONCLUSION
LB80380 at doses of up to 240 mg is safe, well tolerated, and effective at reducing viral load in CHB patients with lamivudine-resistant virus for a period of 12 weeks.
Lymphomatoid papulosis while on efalizumab.

REFERENCES 1. Chung VQ, Moschella SL, Zembowicz A, Liu V. Clinical and pathologic findings of paraneoplastic dermatoses. J Am Acad Dermatol 2006;54:745-62. 2. Patel N, Spencer LA, English JC 3rd, Zirwas MJ. Acquired ichthyosis. J Am Acad Dermatol 2006;55:647-56. 3. Poligone B, Christensen SR, Lazova R, Heald PW. Bazex syndrome (acrokeratosis paraneoplastica). Lancet 2007;369:530. 4. Rubisz-Brzezińska J, Zebracka T, Musiałowicz D. Coexistence of 2 paraneoplastic syndromes—acrokeratosis bazex and LeserTrèlat syndrome—in a case of squamous-cell laryngeal cancer [in Polish]. Przegl Dermatol 1983;70:205-8. 5. Bazex J, el Sayed F, Sans B, Marguery MC, Samalens G. Bazex paraneoplastic acrokeratosis associated with acquired ichthyosis, pigmentation disorders and pruritus: a late disclosure of laryngeal neoplasms [in French]. Ann Dermatol Venereol 1992;119:483-5.