LLukas22/scidocs huggingface dataset:
A hybrid method to face class overlap and class imbalance on neural networks and multi-class scenarios

Class imbalance and class overlap are two of the major problems in data mining and machine learning. Several studies have shown that these data complexities may affect the performance or behavior of artificial neural networks. Strategies proposed to face with both challenges have been separately applied. In this paper, we introduce a hybrid method for handling both class imbalance and class overlap simultaneously in multi-class learning problems. Experimental results on five remote sensing data show that the combined approach is a promising method. 2012 Elsevier B.V. All rights reserved.
Paramedian vertical palatal bone height for mini-implant insertion: a systematic review.

Paramedian insertion of orthodontic mini-implants is increasingly used to anchor molar distalizers. The aim of this review was to systematically examine the available measurements of vertical palatal bone height (VBH). PUBMED, MEDLINE and the Cochrane Controlled Trials Register were searched using specific search terms. Hand searches of bibliographies of articles were also performed to identify studies measuring VBH or bone thickness in the human palate. Sixteen studies were included, arising from 19 published articles. Repeat presentations were excluded. Ten of the 11 computed tomogram (CT)-based studies presented data from 956 orthodontic patients on average VBH and its variation at a range of palatal sites. Individual data were not available, and pooling of data was not feasible because of heterogeneity of subjects, different measurement sites, different CT methods and their associated software. The compilation of data did indicate that the region 3-4mm behind the incisive foramen and 3-9mm lateral to the midpalatal suture should normally provide sufficient VBH to anchor molar distalizers. The risks of unwanted effects during distalization should be small, but the limitations listed above and the small numbers of studies available impair the precision of the estimates and do not allow the results to be generalized. Paramedian anchorage in the anterior palate can be recommended for molar distalization but, given the great inter-individual variability of the palatal bone height, it must be preceded by reliable CT-based imaging in patients identified by routine investigations as being at risk.
Conversion on the road to Damascus 2: minority report of the political (or how to have an adventure, after metaphysics)

This is the third meditation on the question of time, movement, metaphysics and art. It was enacted/installed/ read as part of a think-tank held at the Pacific Institute for Technology and Culture, Univ of Victoria where Professor Golding was invited June 2009. An earlier version was presented at the European Project for Poetics and Hermeneutics: Memory and Interpretation (The Macedonian Academy of Sciences and Arts, Skopkje). Published later in R. Garnett: Gest: Laboratory of Synthesis (Bookworks:2010). CF GALA reference.
Group a Streptococcus causing necrotizing fasciitis and toxic shock syndrome after medical termination of pregnancy.

BACKGROUND
Group A Streptococcus is an aerobic gram-positive bacteria known to cause cutaneous infections. Invasive infections can lead to toxic shock syndrome with multiorgan failure and mortality rates of 25-48%.


CASE
A healthy, young woman developed necrotizing fasciitis, myonecrosis, and toxic shock syndrome after an elective medical termination of pregnancy. This patient had confirmed group A Streptococcus on blood cultures and underwent surgical debridement. After aggressive surgical treatment, below-the-knee amputation, and antibiotic therapy, the patient survived.


CONCLUSION
This case demonstrates the need for prompt recognition and treatment of necrotizing fasciitis/toxic shock syndrome.
Performance evaluation and model checking join forces

A call for the perfect marriage between classical performance evaluation and state-of-the-art verification techniques.
Transosseous-equivalent rotator cuff repair: a systematic review on the biomechanical importance of tying the medial row.

PURPOSE
Double-row and transosseous-equivalent repair techniques have shown greater strength and improved healing than single-row techniques. The purpose of this study was to determine whether tying of the medial-row sutures provides added stability during biomechanical testing of a transosseous-equivalent rotator cuff repair.


METHODS
We performed a systematic review of studies directly comparing biomechanical differences.


RESULTS
Five studies met the inclusion and exclusion criteria. Of the 5 studies, 4 showed improved biomechanical properties with tying the medial-row anchors before bringing the sutures laterally to the lateral-row anchors, whereas the remaining study showed no difference in contact pressure, mean failure load, or gap formation with a standard suture bridge with knots tied at the medial row compared with knotless repairs.


CONCLUSIONS
The results of this systematic review and quantitative synthesis indicate that the biomechanical factors ultimate load, stiffness, gap formation, and contact area are significantly improved when medial knots are tied as part of a transosseous-equivalent suture bridge construct compared with knotless constructs. Further studies comparing the clinical healing rates and functional outcomes between medial knotted and knotless repair techniques are needed.


CLINICAL RELEVANCE
This review indicates that biomechanical factors are improved when the medial row of a transosseous-equivalent rotator cuff is tied compared with a knotless repair. However, this has not been definitively proven to translate to improved healing rates clinically.
Plasma Phospholipid Fatty Acid Biomarkers of Dietary Fat Quality and Endogenous Metabolism Predict Coronary Heart Disease Risk: A Nested Case‐Control Study Within the Women's Health Initiative Observational Study

BACKGROUND
Although the relationship between dietary fat quality and coronary heart disease (CHD) risk has been evaluated, typically using diet questionnaires, results are inconsistent and data in postmenopausal women are limited. Plasma phospholipid fatty acid (PL-FA) profiles, reflecting dietary intake and endogenous FA metabolism, may better predict diet-CHD risk.


METHODS AND RESULTS
Using a nested case-control design, we assessed the association between plasma PL-FA profiles and CHD risk in 2448 postmenopausal women (1224 cases with confirmed CHD and 1224 controls matched for age, enrollment date, race/ethnicity, and absence of CHD at baseline and after 4.5 years of follow-up) participating in the Women's Health Initiative observational study. PL-FA profile was measured using gas chromatography. Product/precursor ratios were used to estimate stearoyl-CoA-desaturase (16:1n-7/16:0, 18:1n-9/18:0), Δ6-desaturase (20:3n-6/18:2n-6), and Δ5-desaturase (20:4n-6/20:3n-6) activities, indicators of endogenous FA metabolism. Multivariate conditional logistic regression was used to obtain odds ratios (95% CIs) for CHD risk. While no associations were observed for the predominant PL fatty acid (16:0, 18:0, 18:1n-9, and 18:2n-6), plasma PL-saturated fatty acid (1.20 [1.08 to 1.32]) and endogenously synthesized PL ω6 fatty acids (20:3n-6; 3.22 [1.95 to 5.32]), 22:5n-6; 1.63 [1.20 to 2.23]) and Δ6-desaturase (1.25 [1.11 to 1.41]) were positively associated with CHD risk. PL-ω3 fatty acids (20:5n-3; 0.73 [0.58 to 0.93], 22:5n-3; 0.56 [0.33 to 0.94], 22:6n-3; 0.56 [0.39 to 0.80]), 18:1n-7 (0.54 [0.29 to 0.99]), and Δ5-desaturase (0.78 [0.70 to 0.88]) were inversely associated with CHD risk. Results support current guidelines regarding regular fish consumption. Additional findings include associations between endogenously synthesized fatty acids and CHD risk, which were partly explained by changes in Δ6-desaturase and Δ5-desaturase indexes, suggesting that in vivo metabolism may also play an important role in predicting CHD risk in this cohort of postmenopausal women.


CLINICAL TRIAL REGISTRATION URL
http://ClinicalTrials.gov, Unique identifier: NCT01864122.
Academic Tweet Classification with Spreading activation based Label propagation algorithm using Tweet centric features

Social network like Twitter is used by researchers and academicians to develop their professional relationship and as well it acts as a communication tool to share their research ideas, and research results. Among the enormous number of tweets, certain tweets contain general information and others might contain academic related information that aid scholarly communication. In order to identify such tweets, our work aims to classify the tweets as academic or non-academic tweet based on new combination of tweet content features like hashtags, terms that influence academic domain and user related features like follower/followee graph, mentions and tweet reply status. Spreading activation based Label propagation algorithm is used for tweet classification. In order to choose the appropriate random neighbor and effectively propagate the labels, the activation value computed by Spreading activation is used. Further, this helps to reduce the number of iterations and thereby, speeds up the convergence of the Label propagation algorithm. The comprehensive experimental results shows that spreading activation based Label propagation algorithm effectively classifies the tweets as academic or non-academic using the inferred academic feature combination with marginal decrease in the number of iterations.
Formation of precise 2D Au particle arrays via thermally induced dewetting on pre-patterned substrates

The fabrication of precise 2D Au nanoparticle arrays over a large area is presented. The technique was based on pre-patterning of the substrate before the deposition of a thin Au film, and the creation of periodic particle arrays by subsequent dewetting induced by annealing. Two types of pre-patterned substrates were used: The first comprised an array of pyramidal pits and the second an array of circular holes. For the dewetting of Au films on the pyramidal pit substrate, the structural curvature-driven diffusion cooperates with capillarity-driven diffusion, resulting in the formation of precise 2D particle arrays for films within a structure dependent thickness-window. For the dewetting of Au films on the circular hole substrate, the periodic discontinuities in the films, induced by the deposition, can limit the diffusion paths and lead to the formation of one particle per individual separated region (holes or mesas between holes), and thus, result in the evolution of precise 2D particle arrays. The influence of the pre-patterned structures and the film thickness is analyzed and discussed. For both types of pre-patterned substrate, the Au film thickness had to be adjusted in a certain thickness-window in order to achieve the precise 2D particle arrays.
Carcinoma of the conjunctiva and HIV infection in Uganda and Malawi.

AIM
To investigate the association of human immunodeficiency virus (HIV) infection and carcinoma of the conjunctiva in Africa, and the role of human papilloma virus type 16 (HPV-16).


METHODS
Patients in Uganda and Malawi presenting to eye clinics with lesions suspicious of carcinoma were studied. Pathological confirmation of eye lesions was sought. HIV testing of patients who were biopsied and, in Uganda, of matched case control subjects was carried out as was testing of a sample of fixed biopsies for HPV-16 by polymerase chain reaction (PCR). The HIV-1 serology, histopathology of conjunctival biopsies (conjunctival intraepithelial neoplasia (CIN), invasive carcinoma, other lesions), and prevalence of HPV-16 infection were determined.


RESULTS
Of Ugandan patients, 27/38 (71%) with carcinoma (27 invasive carcinoma, 11, CIN) were HIV positive compared with 12/76 (16%) of controls (odds ratio 13, 95% confidence interval 5-38). The calculated population aetiological fraction of carcinoma associated with HIV was 66%. Of 32 Malawian patients (20 invasive carcinoma, 12 CIN), 25/29 tested (86%) were HIV positive. HPV-16 infection was found in 7/20 (35%) of carcinoma samples, 0/9 pingueculae, and 2/6 conjunctivitis samples.


CONCLUSIONS
HIV infection is strongly associated with an apparent increase in the incidence of conjunctival carcinoma in Africa. While ultraviolet light is probably the prime risk factor and HPV-16 is implicated in a proportion of cases, the interactions of ultraviolet light, HIV, HPVs, and other factors are unclear in the pathogenesis of carcinoma. The disease represents another model of multifactorial epithelial carcinogenesis.
Authentication and Access Control in the Internet of Things

Due to the inherent vulnerabilities of the Internet, security and privacy issues should be considered and addressed before the Internet of Things is widely deployed. This paper mainly analyzes existing authentication and access control methods, and then, it designs a feasible one for the Internet of Things.
Female genital injuries resulting from consensual and non-consensual vaginal intercourse.

OBJECTIVES
The purpose of this study was to compare the incidence of genital injury following penile-vaginal penetration with and without consent.


DESIGN
This study compared observations of genital injuries from two cohorts.


SETTING
Participants were drawn from St. Mary's Sexual Assault Referral Centre and a general practice surgery in Manchester, and a general practice surgery in Buckinghamshire.


PARTICIPANTS
Two cohorts were recruited: a retrospective cohort of 500 complainants referred to a specialist Sexual Assault Referral Centre (the Cases) and 68 women recruited at the time of their routine cervical smear test who had recently had sexual intercourse (the Comparison group).


MAIN OUTCOME MEASURES
Presence of genital injuries.


RESULTS
22.8% (n=00, 95% CI 19.2-26.7) of adult complainants of penile-vaginal rape by a single assailant sustained an injury to the genitalia that was visible within 48h of the incident. This was approximately three times more than the 5.9% (n=68, 95% CI 1.6-14.4) of women who sustained a genital injury during consensual sex. This was a statistically significant difference (a<0.05, p=0.0007). Factors such as hormonal status, position during intercourse, criminal justice outcome, relationship to assailant, and the locations, sizes and types of injuries were also considered but the only factor associated with injury was the relationship with the complainant, with an increased risk of injury if the assailant was known to the complainant (p=0.019).


CONCLUSIONS
Most complainants of rape (n=500, 77%, 95% CI 73-81%) will not sustain any genital injury, although women are three times more likely to sustain a genital injury from an assault than consensual intercourse.
Generate Believable Causal Plots with User Preferences Using Constrained Monte Carlo Tree Search

We construct a large scale of causal knowledge in term of Fabula elements by extracting causal links from existing common sense ontology ConceptNet5. We design a Constrained Monte Carlo Tree Search (cMCTS) algorithm that allows users to specify positive and negative concepts to appear in the generated stories. cMCTS can find a believable causal story plot. We show the merits by experiments and discuss the remedy strategies in cMCTS that may generate incoherent causal plots. keywords: Fabula elements, causal story plots, constrained Monte Carlo Tree Search, user preference, believable story generation
Efficacy and resistance to telbivudine treatment in chronic hepatitis B patients with favorable predictors: a multicenter study in Taiwan.

BACKGROUND/PURPOSE
A subgroup analysis of a GLOBE study identified subgroups of chronic hepatitis B (CHB) patients with excellent outcomes to telbivudine (LdT) treatment. The aim of this study was to validate this concept using a real-world clinical population.


METHODS
This prospective, retrospective, and multicenter study examined both HBeAg-positive and HBeAg-negative CHB patients treated with LdT for 2 years.


RESULTS
A total of 116 CHB patients were recruited. Of the 64 HBeAg-positive patients, 35 had favorable baseline characteristics [hepatitis B virus (HBV) DNA ≤ 9 log(10) copies/mL and alanine aminotransferase ≥ 2× the upper limit of normal (ULN)], but only 40% (14/35) achieved polymerase chain reaction (PCR) negativity at week 24. Among the 14 patients with favorable baseline characteristics and on-treatment response, the rates of virologic, biochemical, and serologic response and genotypic resistance were 78.6% (11/14), 64.3% (9/14), 50% (7/14), and 7.1% (1/14), respectively, at week 104 of therapy. Of the 52 HBeAg-negative patients, 34 met the criteria of a baseline serum HBV-DNA level less than 7 log(10) copies/mL, and 29 (85.3%) achieved PCR negativity at week 24. Among the 29 patients with favorable baseline characteristics and on-treatment response, the rates of virologic and biochemical response and genotypic resistance were 96.6% (28/29), 72.4% (21/29), and 6.9% (2/29), respectively. In addition, the PCR negativity at week 24 was the only factor associated with the virologic response and genotypic resistance to LdT treatment.


CONCLUSION
The efficacy and resistance to LdT treatment in CHB patients with favorable predictors were comparable between a real-world clinical population and the GLOBE study. In addition, PCR negativity at week 24 could predict virologic response and genotypic resistance to LdT treatment.
Effect of Different Insoles on Postural Balance: A Systematic
Review

[Purpose] The aim of the present study was to perform a systematic review of the literature on the effect of different insoles on postural balance. [Subjects and Methods] A systematic review was conducted of four databases. The papers retrieved were evaluated based on the following inclusion criteria: 1) design: controlled clinical trial; 2) intervention: insole; 3) outcome: change in static postural balance; and 4) year of publication: 2005 to 2012. [Results] Twelve controlled trials were found comparing the effects of different insoles on postural balance. The papers had methodological quality scores of 3 or 4 on the PEDro scale. [Conclusion] Insoles have benefits that favor better postural balance and control.
Structural insights into RNA Processing by the Human RISC-Loading Complex

Targeted gene silencing by RNA interference (RNAi) requires loading of a short guide RNA (small interfering RNA (siRNA) or microRNA (miRNA)) onto an Argonaute protein to form the functional center of an RNA-induced silencing complex (RISC). In humans, Argonaute2 (AGO2) assembles with the guide RNA–generating enzyme Dicer and the RNA-binding protein TRBP to form a RISC-loading complex (RLC), which is necessary for efficient transfer of nascent siRNAs and miRNAs from Dicer to AGO2. Here, using single-particle EM analysis, we show that human Dicer has an L-shaped structure. The RLC Dicer's N-terminal DE×H/D domain, located in a short 'base branch', interacts with TRBP, whereas its C-terminal catalytic domains in the main body are proximal to AGO2. A model generated by docking the available atomic structures of Dicer and Argonaute homologs into the RLC reconstruction suggests a mechanism for siRNA transfer from Dicer to AGO2.
Unsupervised Attention-guided Image-to-Image Translation

Current unsupervised image-to-image translation techniques struggle to focus their attention on individual objects without altering the background or the way multiple objects interact within a scene. Motivated by the important role of attention in human perception, we tackle this limitation by introducing unsupervised attention mechanisms that are jointly adversarially trained with the generators and discriminators. We demonstrate qualitatively and quantitatively that our approach attends to relevant regions in the image without requiring supervision, which creates more realistic mappings when compared to those of recent approaches. Input Ours CycleGAN [1] RA [2] DiscoGAN [3] UNIT [4] DualGAN [5] Figure 1: By explicitly modeling attention, our algorithm is able to better alter the object of interest in unsupervised image-to-image translation tasks, without changing the background at the same time.
The promise of zoomable user interfaces

Zoomable User Interfaces (ZUIs), now over 15 years old, are an interface approach for searching and browsing visual information spatially. ZUIs organize information on a large flat surface with animated transitions to show movement through space. They have been the subject of research in the areas of implementation, design approach, efficacy, and application. And now they are commercially available in a number of domains. But at the same time, they are not used as widely as early researchers envisioned.
3-D relative positioning sensor for indoor flying robots

Swarms of indoor flying robots are promising for many applications, including searching tasks in collapsing buildings, or mobile surveillance and monitoring tasks in complex man-made structures. For tasks that employ several flying robots, spatial-coordination between robots is essential for achieving collective operation. However, there is a lack of on-board sensors capable of sensing the highlydynamic 3-D trajectories required for spatial-coordination of small indoor flying robots. Existing sensing methods typically utilise complex SLAM based approaches, or absolute positioning obtained from off-board tracking sensors, which is not practical for real-world operation. This paper presents an adaptable, embedded infrared based 3-D relative positioning sensor that also operates as a proximity sensor, which is designed to enable inter-robot spatial-coordination and goal-directed flight. This practical approach is robust to varying indoor environmental illumination conditions and is computationally simple.
Prosodic Units in Speech Production

Four experiments demonstrate effects of prosodic structure on speech production latencies. Experiments 1 to 3 exploit a modified version of the Sternberg et al. (1978, 1980) prepared speech production paradigm to look for evidence of the generation of prosodic structure during the final stages of sentence production. Experiment 1 provides evidence that prepared sentence production latency is a function of the number of phonological words that a sentence comprises when syntactic structure, number of lexical items, and number of syllables are held constant. Experiment 2 demonstrated that production latencies in Experiment 1 were indeed determined by prosodic structure rather than the number of content words that a sentence comprised. The phonological word effect was replicated in Experiment 3 using utterances with a different intonation pattern and phrasal structure. Finally, in Experiment 4, an on-line version of the sentence production task provides evidence for the phonological word as the preferred unit of articulation during the on-line production of continuous speech. Our findings are consistent with the hypothesis that the phonological word is a unit of processing during the phonological encoding of connected speech. q 1997 Academic Press