LLukas22/scidocs huggingface dataset:
Tomato Lycopene : Functional Proprieties and Health Benefits

The growing concerns for physical wellbeing and health have been reflected in the way we choose food in our table. Nowadays, we are all more informed consumers and choose healthier foods. On the other hand, stroke, cancer and atherosclerosis may be somehow minimized by the intake of some bioactive compounds present in food, the so-called nutraceuticals and functional foods. The aim of this work was to make a revision of the published studies about the effects of some bioactive compounds, namely lycopene in human health, in the prevention of diseases, thus playing the role of a functional food. Free radical in human body can induce cell damage and consequently can be responsible for the development of some cancers and chronic diseases. Lycopene is one of the most powerful antioxidants known, being the predominant carotenoid in tomato. The respective chemistry, bioavailability, and its functional role in the prevention of several diseases will be object of this work. On the other hand, the inclusion of lycopene in some foods can also be made by biotechnology and represents a way to recover the wastes in the tomato industry with nutritional positive effects in health. Keywords—Tomato, lycopene, bioavailability, functional foods, carotenoids, cancer and antioxidants.
Device-centric radio access virtualization for 5G networks

In this paper, we introduce a virtualized device-centric radio access architecture for future fifth-generation (5G) mobile networks. Radio access networks (RAN)s have traditionally relied on Voronoi tessellations of cells, created by a careful deployment of access nodes, to enable spatial frequency reuse over those cells. With the trend firmly set to decouple the control- and user-planes for next-generation 5G mobile networks, we foresee radio access technology breaking away from the concept of cells and embracing a virtualized device-centric architecture. The aim for this paradigm shift is to meet the stringent quality of service (QoS) requirements of densely populated networks irrespective of users' physical proximity to the access nodes. Focusing on downlink user-plane (U-plane) virtualization, this paper proposes a device-centric hyper-transceiver (HT) design that capitalizes on group-to-group (G2G) communications between virtual multipoint transmission and reception nodes and proactively optimizes both sets of virtual nodes via dynamic point selection (DPS) enabled by cloud-RAN (CRAN) architecture and semi-static network-assisted receiver cooperation enabled by device-to-device (D2D) short-range communications, respectively. Using a full-fledged event-based system level simulator compliant with the 3rd generation partnership project (3GPP) long-term evolution advanced (LTE-Adv) specifications, our results show that the proposed virtualized U-plane architecture provides more than 50% average throughput and 200% coverage gains over LTE-A Release 11 baseline under some typical simulation scenarios.
Trajectories of estradiol and follicle-stimulating hormone over the menopause transition and early markers of atherosclerosis after menopause.

AIM
The purpose of this study was to assess associations between distinct patterns of circulating estradiol (E2) and follicle-stimulating hormone (FSH) over the menopause transition (MT) and subclinical measures of atherosclerosis after menopause.


METHODS AND RESULTS
Four temporal patterns of E2 decline (Low: low before and after final menstrual period (FMP); Medium: medium before and high after FMP; High-early decline: high prior to FMP and early decline thereafter; High-late decline: high prior to FMP and late decline thereafter) and three of FSH rise (Low, Medium, High) over 9.6 years across FMP were identified and linked to carotid intima-media-thickness (IMT), adventitial diameter (AD), and presence of carotid plaque (cPlaque) measured after menopause at the 12th annual visit (visit 12). Participants were 856 women (age at visit 12 = 59.5 ± 2.7 years) from the Study of Women's Health Across the Nation (SWAN), who never reported a stroke or a heart attack. In models adjusted for visit 12 or baseline cardiovascular disease (CVD) risk factors, odds of having any cPlaque were ∼43% lower among women with the High-early decline E2 trajectory compared to women with the Low E2 trajectory. In contrast, women with the Medium E2 trajectory had significantly higher IMT than those with the Low E2 trajectory adjusting for visit 12 CVD risk factors. Interestingly, adjusting for baseline CVD risk factors attenuated this association. The Low FSH group had lower IMT than the Medium and High FSH groups (p ≤ 0.05) in all models.


CONCLUSION
During MT, women are subjected to hormonal alterations that could potentially increase their risk of developing CVD after menopause.
Adaptation , adaptive capacity and vulnerability

This paper reviews the concept of adaptation of human communities to global changes, especially climate change, in the context of adaptive capacity and vulnerability. It focuses on scholarship that contributes to practical implementation of adaptations at the community scale. In numerous social science fields, adaptations are considered as responses to risks associated with the interaction of environmental hazards and human vulnerability or adaptive capacity. In the climate change field, adaptation analyses have been undertaken for several distinct purposes. Impact assessments assume adaptations to estimate damages to longer term climate scenarios with and without adjustments. Evaluations of specified adaptation options aim to identify preferred measures. Vulnerability indices seek to provide relative vulnerability scores for countries, regions or communities. The main purpose of participatory vulnerability assessments is to identify adaptation strategies that are feasible and practical in communities. The distinctive features of adaptation analyses with this purpose are outlined, and common elements of this approach are described. Practical adaptation initiatives tend to focus on risks that are already problematic, climate is considered together with other environmental and social stresses, and adaptations are mostly integrated or mainstreamed into other resource management, disaster preparedness and sustainable development programs. r 2006 Elsevier Ltd. All rights reserved.
Drug-induced changes in fibrillation cycle length and organization index can predict chemical cardioversion of long-lasting atrial fibrillation with bepridil alone or in combination with aprindine.

BACKGROUND
The aim of this study was to investigate whether drug-induced changes in fibrillation wave characteristics can predict pharmacological conversion of long lasting persistent atrial fibrillation (AF).


METHODS AND RESULTS
The study group comprised 23 consecutive patients with AF lasting > or =1 month. Patients first received bepridil (200 mg/day) for 2-4 weeks. When sinus rhythm was not restored with bepridil, oral aprindine (40 or 60 mg/day) was added to bepridil. Fast Fourier transform analysis of fibrillation waves using lead V1 was performed to calculate the fibrillation cycle length (FCL). The spectral areas were measured and the maximum area divided by the total area was termed the fibrillation organization index (FOI). Sinus rhythm was restored in 16 of 23 patients (70%); 8 of these 16 patients received only bepridil (Group I) and the other 8 responders received bepridil and aprindine (Group II). In Group I bepridil increased both FCL (p<0.001) and FOI (p<0.01) and terminated AF after 20+/-12 days. In Group II bepridil increased FCL (p<0.001), but did not change FOI. The addition of aprindine terminated AF in association with an increase in both FCL (p<0.005) and FOI (p<0.005) within 19+/-8 days. In the remaining 7 patients who did not have restoration of sinus rhythm, bepridil increased both FCL and FOI significantly, but less than in Group I, and the addition of aprindine did not further increase either of them. Chemical cardioversion of AF occurred in all patients with FCL > or =190 ms and FOI > or =45% after drug administration.


CONCLUSION
Bepridil alone or in combination with aprindine converted long lasting persistent AF in association with an increase in both FCL and FOI. The combination of FCL and FOI after drug administration is helpful in predicting chemical cardioversion of persistent AF.
Patients with schizophrenia treated with aripiprazole, a multicentre naturalistic study.

OBJECTIVE
The purpose was to carry out a naturalistic study on efficacy, safety and tolerability of aripiprazole during treatment of schizophrenia. Fifty-one patients with an ICD-10 diagnosis of schizophrenia and partial responders to prior antipsychotic medication were offered treatment with aripiprazole as monotherapy or in combination their prior medication. Inclusion criteria were lack of therapeutic effect or adverse events on former antipsychotic treatment.


METHOD
Six-month open multicentre naturalistic study with prospective assessments including Body Mass Index (BMI), Clinical Global Impression-Severity (CGI-S), Clinical Global Impression-Improvement, Global Assessment of Functioning Scale (GAF) and adverse events.


RESULTS
A statistically significant improvement in the different measures of psychopathology and global functioning (CGI-S reduction 34.7%; GAF improvement 14%) was shown in combination with a statistically significant reduction in BMI of 2.9%. Nine patients (17.6%) did not complete the 6-month treatment.


CONCLUSION
In an open multicentre naturalistic study, aripiprazole showed to improve the severity of psychotic symptoms and the global level of functioning. However, many of the patients (47%) were also given another antipsychotic drug at the same time. Also, high compliance and few side effects were reported. However, because of the study design, the results must be interpreted conservatively.
Eyes Based Eletric Wheel Chair Control System - I (eye) can control Electric Wheel Chair -

Eyes base Electric Wheel Chair Control: EBEWC is proposed. The proposed EBEWC is controlled by human eyes only. Therefore disabled person can control the EBEWC by themselves. Most of the computer input system with human eyes only consider in specific condition and does not work in a real time basis. Moreover, it is not robust against various user races, illumination conditions, EWC vibration, and user's movement. Though experiments, it is found that the proposed EBEWC is robust against the aforementioned influencing factors. Moreover, it is confirmed that the proposed EBEWC can be controlled by human eyes only accurately and safely. Keywords-computer input by human eyes only; gaze estimation; electric wheelchair control.
Nonperturbative beta function in three-dimensional electrodynamics

We apply the Schr\"odinger functional method to the Abelian gauge theory in three dimensions with ${N}_{f}=2$ four-component fermions. We find that the calculated beta function does not cross zero in the range of coupling we study. This implies that the theory exhibits confinement and mass generation, rather than a conformal infrared regime.
Project scheduling under multiple resources constraints using a genetic algorithm

The resource constrained project scheduling problem (RCPSP) is a difficult problem in combinatorial optimization for which extensive investigation has been devoted to the development of efficient algorithms. During the last couple of years many heuristic procedures have been developed for this problem, but still these procedures often fail in finding near-optimal solutions. This paper proposes a genetic algorithm for the resource constrained project scheduling problem. The chromosome representation of the problem is based on random keys. The schedule is constructed using a heuristic priority rule in which the priorities and delay times of the activities are defined by the genetic algorithm. The approach was tested on a set of standard problems taken from the literature and compared with other approaches. The computational results validate the effectiveness of the proposed algorithm. Key-Words: Construction management, Project management, Scheduling, Genetic algorithm, RCPSP.
Texture Classification Approach Based on Combination of Edge & Co-occurrence and Local Binary Pattern

Texture classification is one of the problems which has been paid much attention on by computer scientists since late 90s. If texture classification is done correctly and accurately, it can be used in many cases such as Pattern recognition, object tracking, and shape recognition. So far, there have been so many methods offered to solve this problem. Near all these methods have tried to extract and define features to separate different labels of textures really well. This article has offered an approach which has an overall process on the images of textures based on Local binary pattern and Gray Level Co-occurrence matrix and then by edge detection, and finally, extracting the statistical features from the images would classify them. Although, this approach is a general one and is could be used in different applications, the method has been tested on the stone texture and the results have been compared with some of the previous approaches to prove the quality of proposed approach. Keywords-Texture Classification, Gray level Co occurrence, Local Binary Pattern, Statistical Features
Open R & D and open innovation : exploring the phenomenon

Dr. Manfred Bischoff Institute of Innovation Management of EADS, Zeppelin University, Am Seemoser Horn 20, D-88045 Friedrichshafen, Germany. ellen.enkel@zeppelin-university.de Institute of Technology Management, University of St. Gallen, Dufourstrasse 40a, CH-9000 St. Gallen, Switzerland. oliver.gassmann@unisg.ch Center for Open Innovation, Haas School of Business, Faculty Wing, F402, University of California, Berkeley, Berkeley, CA 94720-1930, USA. chesbrou@haas.berkeley.edu
A novel nonlinear ensemble forecasting model incorporating GLAR and ANN for foreign exchange rates

In this study, we propose a novel nonlinear ensemble forecasting model integrating generalized linear autoregression (GLAR) with artificial neural networks (ANN) in order to obtain accurate prediction results and ameliorate forecasting performances. We compare the new model’s performance with the two individual forecasting models—GLAR and ANN—as well as with the hybrid model and the linear combination models. Empirical results obtained reveal that the prediction using the nonlinear ensemble model is generally better than those obtained using the other models presented in this study in terms of the same evaluation measurements. Our findings reveal that the nonlinear ensemble model proposed here can be used as an alternative forecasting tool for exchange rates to achieve greater forecasting accuracy and improve prediction quality further. 2004 Elsevier Ltd. All rights reserved.
Gamification - Design of IT-Based Enhancing Services for Motivational Support and Behavioral Change

Received: 2013-04-15 Accepted: 2013-05-13 Accepted after one revision by Prof. Dr. Sinz. Published online: 2013-06-14 This article is also available in German in print and via http://www. wirtschaftsinformatik.de: Blohm I, Leimeister JM (2013) Gamification. Gestaltung IT-basierter Zusatzdienstleistungen zur Motivationsunterstützung und Verhaltensänderung. WIRTSCHAFTSINFORMATIK. doi: 10.1007/s11576-013-0368-0.
Transcranial Direct Current Stimulation to Enhance Dual-Task Gait Training in Parkinson’s Disease: A Pilot RCT

OBJECTIVE
To investigate the feasibility and safety of a combined anodal transcranial direct current stimulation (tDCS) and dual task gait training intervention in people with Parkinson's Disease (PD) and to provide data to support a sample size calculation for a fully powered trial should trends of effectiveness be present.


DESIGN
A pilot, randomized, double-blind, sham-controlled parallel group trial with 12 week follow-up.


SETTING
A university physiotherapy department.


INTERVENTIONS
Sixteen participants diagnosed with PD received nine dual task gait training sessions over 3 weeks. Participants were randomized to receive either active or sham tDCS applied for the first 20 minutes of each session.


MAIN MEASURES
The primary outcome was gait speed while undertaking concurrent cognitive tasks (word lists, counting, conversation). Secondary measures included step length, cadence, Timed Up and Go, bradykinesia and motor speed.


RESULTS
Gait speed, step length and cadence improved in both groups, under all dual task conditions. This effect was maintained at follow-up. There was no difference between the active and sham tDCS groups. Time taken to perform the TUGwords also improved, with no difference between groups. The active tDCS group did however increase their correct cognitive response rate during the TUGwords and TUGcount. Bradykinesia improved after training in both groups.


CONCLUSION
Three weeks of dual task gait training resulted in improved gait under dual task conditions, and bradykinesia, immediately following training and at 12 weeks follow-up. The only parameter enhanced by tDCS was the number of correct responses while performing the dual task TUG. tDCS applied to M1 may not be an effective adjunct to dual task gait training in PD.


TRIAL REGISTRATION
Australia-New Zealand Clinical Trials Registry ACTRN12613001093774.
Scaling agile software development through lean governance

Agile project teams are potentially easy to govern than traditional project teams due to the greater visibility and opportunities to steer provided to stakeholders. Unfortunately, traditional IT governance strategies prove to be at odds to agile's collaborative, value-focused strategies. As a result a lean approach based on enablement, collaboration, and motivation is required to effectively govern agile teams.
Mortality and cancer incidence among Lithuanian cement producing workers.

AIMS
To investigate mortality and cancer incidence of cement producing workers.


METHODS
A total of 2498 cement workers who have been employed at Portland cement producing departments for at least one year from 1956 to 2000 were followed up from 1 January 1978 to 31 December 2000. The cohort contributed 43,490 person-years to the study. Standardised incidence ratios (SIR) and standardised mortality ratios (SMR) were calculated as ratios between observed and expected numbers of cancers and deaths. The expected numbers were based on sex specific incidence and mortality rates for the total Lithuanian population.


RESULTS
Significantly increased SMRs were found for all malignant neoplasms (SMR 1.3, 95% CI 1.0 to 1.5) and for lung cancer (SMR 1.4, 95% CI 1.0 to 1.9) among male cement workers. SIR for all cancer sites was 1.2 (95% CI 1.0 to 1.4). Excess risk was found for cancer of the lung (SIR 1.5, 95% CI 1.1 to 2.1). The SIR for urinary bladder cancer was also increased (SIR 1.8, 95% CI 0.9 to 3.5). The overall cancer incidence was not increased among females (SIR 0.8, 95% CI 0.6 to 1.1). With increasing cumulated exposure to cement dust, there were indications of an increasing risk of lung and stomach cancers among males.


CONCLUSIONS
This study supported the hypothesis that exposure to cement dust may increase the lung and bladder cancer risk. A dose related risk was found for stomach cancer, but no support was found for an increased risk of colorectal cancer.
Orthosis noncompliance after the Ponseti method for the treatment of idiopathic clubfeet: a relevant problem that needs reevaluation.

INTRODUCTION
Idiopathic talipes equinovarus is the most common congenital defect characterized by the presence of a congenital dysplasia of all musculoskeletal tissues distal to the knee. For many years, the treatment has been based on extensive surgery after manipulation and cast trial. Owing to poor surgical results, Ponseti developed a new treatment protocol consisting of manipulation with cast and an Achilles tenotomy. The new technique requires 4 years of orthotic management to guarantee good results. The most recent studies have emphasized how difficult it is to comply with the orthotic posttreatment protocol. Poor compliance has been attributed to parent's low educational and low income level. The purpose of the study is to evaluate if poor compliance is due to the complexity of the orthotic use or if it is related to family education, cultural, or income factors.


METHOD
Fifty-three patients with 73 idiopathic talipes equinovarus feet were treated with the Ponseti technique and followed for 48 months after completing the cast treatment. There was a male predominance (72%). The mean age at presentation was 1 month (range: 1 wk to 7 mo). Twenty patients (38%) had bilateral involvement, 17 patients (32%) had right side affected, and 16 patients (30%) had the left side involved. The mean time of manipulation and casting treatment was 6 weeks (range: 4 to 10 wk). Thirty-eight patients (72%) required Achilles tenotomy as stipulated by the protocol. Recurrence was considered if there was a deterioration of the Dimeglio severity score requiring remanipulation and casting.


RESULTS
Twenty-four out of 73 feet treated by our service showed the evidence of recurrence (33%). Sex, age at presentation, cast treatment duration, unilateral or bilateral, severity score, the necessity of Achilles tenotomy, family educational, or income level did not reveal any significant correlation with the recurrence risk. Noncompliance with the orthotic use showed a significant correlation with the recurrence rate. The noncompliance rate did not show any correlation with the patient demographic data or parent's education level, insurance, or cultural factors as proposed previously.


CONCLUSION
The use of the brace is extremely relevant with the Ponseti technique outcome (recurrence) in the treatment of idiopathic talipes equinovarus. Noncompliance is not related to family education, cultural, or income level. The Ponseti postcasting orthotic protocol needs to be reevaluated to a less demanding option to improve outcome and brace compliance.