LLukas22/scidocs huggingface dataset:
Sodium, Saturated Fat, and Trans Fat Content Per 1,000 Kilocalories: Temporal Trends in Fast-Food Restaurants, United States, 2000–2013

INTRODUCTION
Intakes of sodium, saturated fat, and trans fat remain high despite recommendations to limit these nutrients for cardiometabolic risk reduction. A major contributor to intake of these nutrients is foods prepared outside the home, particularly from fast-food restaurants.


METHODS
We analyzed the nutrient content of frequently ordered items from 3 US national fast-food chains: fried potatoes (large French fries), cheeseburgers (2-oz and 4-oz), and a grilled chicken sandwich. We used an archival website to obtain data on sodium, saturated fat, and trans fat content for these items from 2000 through 2013. The amount of each nutrient per 1,000 kcal was calculated to determine whether there were trends in product reformulation.


RESULTS
Sodium content per 1,000 kcal differed widely among the 3 chains by food item, precluding generalizations across chains. During the 14-year period, sodium content per 1,000 kcal for large French fries remained high for all 3 chains, although the range narrowed from 316-2,000 mg per 1,000 kcal in 2000 to 700-1,420 mg per 1,000 kcal in 2013. Among the items assessed, cheeseburgers were the main contributor of saturated fat, and there was little change in content per 1,000 kcal for this item during the 14-year period. In contrast, there was a sharp decline in saturated and trans fat content of large French fries per 1,000 kcal. Post-2009, the major contributor of trans fat per 1,000 kcal was cheeseburgers; trans fat content of this item remained stable during the 14-year period.


CONCLUSION
With the exception of French fries, little evidence was found during the 14-year period of product reformulation by restaurants to become more consistent with dietary guidance to reduce intakes of sodium and saturated fat.
Search Efficiency but Not Response Interference Affects Visual Selection in Frontal Eye Field

Two manipulations of a visual search task were used to test the hypothesis that the discrimination of a target from distractors by visually responsive neurons in the frontal eye field (FEF) marks the outcome and conclusion of visual processing instead of saccade preparation. First, search efficiency was reduced by increasing the similarity of the distractors to the target. Second, response interference was introduced by infrequently changing the location of the target in the array. Both manipulations increased reaction time, but only the change in search efficiency affected the time needed to select the target by visually responsive neurons. This result indicates that visually responsive neurons in FEF form an explicit representation of the location of the target in the image.
Multi-view self-supervised deep learning for 6D pose estimation in the Amazon Picking Challenge

Robot warehouse automation has attracted significant interest in recent years, perhaps most visibly in the Amazon Picking Challenge (APC) [1]. A fully autonomous warehouse pick-and-place system requires robust vision that reliably recognizes and locates objects amid cluttered environments, self-occlusions, sensor noise, and a large variety of objects. In this paper we present an approach that leverages multiview RGB-D data and self-supervised, data-driven learning to overcome those difficulties. The approach was part of the MIT-Princeton Team system that took 3rd- and 4th-place in the stowing and picking tasks, respectively at APC 2016. In the proposed approach, we segment and label multiple views of a scene with a fully convolutional neural network, and then fit pre-scanned 3D object models to the resulting segmentation to get the 6D object pose. Training a deep neural network for segmentation typically requires a large amount of training data. We propose a self-supervised method to generate a large labeled dataset without tedious manual segmentation. We demonstrate that our system can reliably estimate the 6D pose of objects under a variety of scenarios. All code, data, and benchmarks are available at http://apc.cs.princeton.edu/
Design of reconfigurable manufacturing systems

This paper explains the rationale for the development of reconfigurable manufacturing systems, which possess the advantages both of dedicated lines and of flexible systems. The paper defines the core characteristics and design principles of reconfigurable manufacturing systems (RMS) and describes the structure recommended for practical RMS with RMS core characteristics. After that, a rigorous mathematical method is introduced for designing RMS with this recommended structure. An example is provided to demonstrate how this RMS design method is used. The paper concludes with a discussion of reconfigurable assembly systems. © 2011 The Society of Manufacturing Engineers. Published by Elsevier Ltd. All rights reserved.
Integrating web-based data mining tools with business models for knowledge management

As firms begin to implement web-based presentation and data mining tools to enhance decision support capability, the firm’s knowledge workers must determine how to most effectively use these new web-based tools to deliver competitive advantage. The focus of this study is on evaluating how knowledge workers integrate these tools into their information and knowledge management requirements. The relationship between the independent variables (web-based data mining software tools and business models) and the dependent variable (strategic performance capabilities) is empirically tested in this study. The results from this study demonstrate the positive interaction effect between the tools and models application on strategic performance
Parenting stress among mothers of children with different physical, mental, and psychological problems

BACKGROUND
Parents of children with developmental problems are always bearing a load of stress. The aim of this study is to compare the stress in mothers of children with different disabilities to each other, considering their demographic background.


MATERIALS AND METHODS
This was a cross-sectional study conducted in Isfahan, Iran during 2012 on 285 mothers of 6-12 years old children with chronic physical disease, psychological disorder, and sensory-motor and mental problems. Abedin's parenting stress questionnaire was used and obtained data were analyzed using multivariate analysis of variance or covariance as appropriate.


RESULTS
Mothers of children with sensory-motor mental and chronic physical problems experience more stress than mothers of children with psychological disorders (P < 0.05). The stress score of mothers of children with psychological disorders was lower than the other two groups. Also there was a significant difference between the score of mothers of children with chronic physical problems and mothers of children with psychological disorders regarding parent-child dysfunctional interaction (P < 0.01). A significant difference was observed in terms of stress among mothers of children with sensory-motor mental problems with different number of children (P < 0.05); also mothers of children with chronic physical problems in different levels of education have experienced different levels of parenting stress (P < 0.05).


CONCLUSION
Due to high level of parenting stress among our studied samples, special education and early intervention are needed for parents in our study population in order to deepening their diagnostic knowledge and professional consultation on stress management.
The costs of treating acute heart failure: an economic analysis of the SURVIVE trial.

OBJECTIVE
To estimate the incremental cost per life year gained with levosimendan relative to dobutamine in treatment of acute heart failure based on the Survival of Patients with Acute Heart Failure in Need of Intravenous Inotropic Support (SURVIVE) trial.


METHODS
SURVIVE enrolled 1,327 patients (levosimendan 664, dobutamine 663) from nine nations with 180-day survival from date of randomisation as the primary endpoint. Hospital resource utilisation was determined via clinical case reports. Unit costs were derived from hospital payment schedules for France, Germany and the UK, and represent a third-party payer perspective. Cost-effectiveness analysis was performed for a subset of the SURVIVE patient population selected in accordance with current levosimendan labeling.


RESULTS
Mortality in the levosimendan group was 26 versus 28% for dobutamine (hazard ratio 0.91, 95% confidence interval 0.74-1.13, p=0.40). Initial hospitalisation length of stay was identical (levosimendan 14.4, dobutamine 14.5, p=0.98). Slightly lower rates of readmission were observed for levosimendan relative to dobutamine at 31 (p=0.13) and 180 days (p=0.23). Mean costs excluding study drug were equivalent for the index admission (levosimendan euro5,060, dobutamine euro4,952; p=0.91) and complete episode (levosimendan euro5,396, dobutamine euro5,275; p=0.93).


CONCLUSION
At an acquisition cost of euro600 per vial, there is at least 50% likelihood that levosimendan is cost effective relative to dobutamine if willingness to pay is equal to or greater than euro15,000 per life year gained.
Economic assessment of adjustable maintenance treatment with budesonide/formoterol in a single inhaler versus fixed treatment in asthma

Objectives: To compare the costs and effectiveness of adjustable maintenance dosing with budesonide/formoterol in a single inhaler versus fixed dosing in adults with asthma. Methods: In this prospective, randomised, open-label, parallel-group, multicentre trial conducted in Germany, patients with asthma received budesonide/formoterol 160µg/4.5µg in a single inhaler (Symbicort® Turbuhaler®) with two inhalations twice daily for a 4-week run-in period. Patients were then randomised to either adjustable maintenance dosing (one inhalation twice daily, stepping up to four inhalations twice daily for 1 week if asthma worsened; n = 1679) or fixed dosing (two inhalations twice daily; n = 1618) for 12 weeks. The primary efficacy variable was the change in health-related quality of life (HR-QOL), measured using the Asthma Quality of Life Questionnaire (standardised) during the randomised treatment period. Resource utilisation data were collected in parallel and combined with German unit costs to estimate direct and indirect costs (year 2001 values). Results: Both treatment regimens were equally effective in maintaining HR-QOL and asthma control during the randomised treatment period. However, overall, patients in the adjustable maintenance dosing group took fewer daily inhalations of budesonide/formoterol than those in the fixed-dosing group (mean: 2.63 vs 3.82 inhalations; p < 0.001). Adjustable maintenance dosing was associated with significantly lower asthma-related direct costs compared with fixed dosing (mean: €221 vs €292; p < 0.001). This pattern was maintained when patients were stratified into those with peak expiratory flow (PEF) of 60% to <80% predicted normal and those with PEF of ≥80% predicted normal and when total costs were considered. Conclusion: Adjustable maintenance dosing with budesonide/formoterol in a single inhaler maintained HR-QOL in adult patients with asthma at a significantly lower cost than fixed dosing.
An Interview with Ernest Mancoba

Abstract Ernest Mancoba (1904–2002) was born in Boksburg on the rim of Johannesburg. He first studied at a teachers’ training college in the diocese of Pietersburg, then taught there from 1925 to 1929. He is one of the most unrecognised painters and sculptors of the twentieth century. He began his education at the Christian school of Pietersburg, where in 1929 his Bantu Madonna created a scandal. It showed her barefoot with African features, her hand making the gesture made by Bantu girls on nearing the head of the family. This break with tradition was not limited to iconography but extended by implication to the whole Christian world‐view as upheld in the West. Seven years later the Madonna was placed in the Anglican cathedral of St Mary in Johannesburg. In 1938 he moved to Paris, was imprisoned during the war, then lived in Denmark before going back to Paris at the end of the 1940s. In 1948, with colleagues including Asger Jorn and Karel Appel, he founded the highly influential art‐group CoBrA. He died ...
Modeling the climatic and subsurface stratigraphy controls on the hydrology of a Carolina bay wetland in South Carolina, USA

Restoring depressional wetlands or geographically isolated wetlands such as cypress swamps and Carolina bays on the Atlantic Coastal Plains requires a clear understanding of the hydrologic processes and water balances. The objectives of this paper are to (1) test a distributed forest hydrology model, FLATWOODS, for a Carolina bay wetland system using seven years of water-table data and (2) to use the model to understand how the landscape position and the site stratigraphy affect ground-water flow direction. The research site is located in Bamberg County, South Carolina on the Middle Coastal Plain of the southeastern U.S. (32.88° N, 81.12° W). Model calibration (1998) and validation (1997, 1999–2003) data span a wet period and a long drought period, which allowed us to test the model for a wide range of weather conditions. The major water input to the wetland is rainfall, and output from the wetland is dominated by evapotranspiration. However, the Carolina bay is a flow-through wetland, receiving ground water from the adjacent upland, but recharging the ground-water to lower topographic areas, especially during wet periods in winter months. Hypothetical simulations suggest that ground-water flow direction is controlled by the gradient of the underlying hydrologic restricting layer beneath the wetland-upland continuum, not solely by the topographic gradient of the land surface. Ground-water flow may change directions during transition periods of wetland hydroperiod that is controlled by the balance of precipitation and evapotranspiration, and such changes depend on the underlying soil stratigraphy of the wetland-upland continuum.
Corrigendum: Connectomic reconstruction of the inner plexiform layer in the mouse retina.

This corrects the article DOI: 10.1038/nature12346
BGPR_Reconstruct: A MATLAB® ray-tracing program for nonlinear inversion of first arrival travel time data from zero-offset borehole radar

A MATLAB program was developed to invert first arrival travel time picks from zero offset profiling borehole ground penetrating radar traces to obtain the electromagnetic wave propagation velocities in soil. Zero-offset profiling refers to a mode of operation wherein the centers of the bistatic antennae being lowered to the same depth below ground for each measurement. The inversion uses a simulated annealing optimization routine, whereby the model attempts to reduce the root mean square error between the measured and modeled travel time by perturbing the velocity in a ray tracing routine. Measurement uncertainty is incorporated through the presentation of the ensemble mean and standard deviation from the results of a Monte Carlo simulation. The program features a pre-processor to modify or delete travel time information from the profile before inversion and post-processing through presentation of the ensemble statistics of the water contents inferred from the velocity profile. The program includes a novel application of a graphical user interface to animate the velocity fitting routine. r 2004 Elsevier Ltd. All rights reserved.
The MNIST Database of Handwritten Digit Images for Machine Learning Research [Best of the Web]

In this issue, “Best of the Web” presents the modified National Institute of Standards and Technology (MNIST) resources, consisting of a collection of handwritten digit images used extensively in optical character recognition and machine learning research.
Prevalence and determinants of recent HIV testing among sexually active men who have sex with men in the St. Louis metropolitan area, Missouri, 2008.

BACKGROUND
New human immunodeficiency virus (HIV) diagnoses in the St. Louis metropolitan area, MO, occur predominantly among men who have sex with men (MSM). The Centers for Disease Control and Prevention recommends HIV testing at least annually for sexually active MSM. We examined prevalence and factors associated with recent HIV testing among MSM in the St. Louis area.


METHODS
The 2008 National HIV Behavioral Surveillance system recruited men in 21 US metropolitan areas through venue-based, time-space sampling. Men were interviewed for behavioral risks and testing history. The analysis included men in St. Louis who had engaged in male-male sex during the previous year and excluded men who had tested HIV-positive >12 months before the interviews. Factors associated with testing during the previous 12 months were identified using log-binomial regression.


RESULTS
Among 339 MSM, 198 (58%) had been tested during the previous 12 months. MSM were more likely to have been tested if they were black (adjusted prevalence ratio [APR]: 1.6; 95% confidence interval [CI]: 1.0-2.5); had visited a health care provider during the previous 12 months (APR: 1.6; 95% CI: 1.3-2.1); or had ever disclosed same-sex attractions or male-male sex to health care providers (APR: 1.6; 95% CI: 1.2-2.0). Of the 141 men who were untested within 12 months, 89 (63%) attributed not testing to perceived low risk.


CONCLUSIONS
Nearly half of sexually active MSM in this analysis had not been tested for HIV during the previous year. Annual visits to health care providers during which sexual risk is discussed are likely to promote testing among MSM.
EVALUATION OF THE ZYGOMATIC BUTTRESS AS A DONOR SITE FOR RIDGE AUGMENTATION PRIOR TO IMPLANT INSERTION IN THE ESTHETIC ZONE

INTRODUCTION: Traumatic loss of teeth in the esthetic zone commonly results in significant loss of buccal bone. This leads to reduced esthetics, problems with phonetics and reduction in function. Single tooth replacement has become an indication for implant-based restoration. In case of lack of bone volume the need of surgical reconstruction of the alveolar ridge is warranted. Several bone grafting techniques have been described to ensure sufficient bone volume for implantation. OBJECTIVES: Evaluation of using the zygomatic buttress as an intraoral bone harvesting donor site for pre-implant grafting. MATERIALS AND METHODS: Twelve patients were selected with limited alveolar ridge defect in the esthetic zone that needs bone grafting procedure prior to dental implants. Patients were treated using a 2-stage technique where bone blocks harvested from the zygomatic buttress region were placed as onlay grafts and fixed with osteosynthesis micro screws. After 4 months of healing, screws were removed for implant placement RESULTS: Harvesting of 12 bone blocks were performed for all patients indicating a success rate of 100% for the zygomatic buttress area as a donor site. Final rehabilitation with dental implants was possible in 11 of 12 patients, yielding a success rate of 91.6%. Three patients (25%) had postoperative complications at the donor site and one patient (8.3%) at the recipient site. The mean value of bone width pre-operatively was 3.64 ± .48 mm which increased to 5.47 ± .57 mm post-operatively, the increase in mean value of bone width was statistically significant (p < 0.001). CONCLUSIONS: Harvesting of intraoral bone blocks from the zygomatic buttress region is an effective and safe method to treat localized alveolar ridge defect before implant placement.
Neuropsychological test profile differences between young and old human immunodeficiency virus-positive individuals

Human immunodeficiency virus (HIV) dementia remains as an important cause of neurological morbidity among HIV-seropositive (HIV+) individuals. Differences in the neuropsychological profiles between older and younger HIV+ individuals have not been examined extensively. The objective of this study was to examine the neuropsychological test performance between old and young HIV+ individuals (a) with and without cognitive impairment (total cohort) and (b) with dementia. One hundred thirty-three older (age ≥ 50 years) HIV+ individuals and 121 younger (age 20 to 39 years) HIV+ individuals were evaluated with a standardized neuropsychological test battery. Differences between age groups in the mean z score for each neuropsychological test were determined. The older HIV+ (total) cohort had greater impairment in tests of verbal memory (P = .006), visual memory (P < .002), verbal fluency (P = .001), and psychomotor speed (P < .001) compared to the young HIV+ (total) cohort. After adjusting for differences in education, older HIV+ patients with dementia (n = 31) had a greater deficit in the Trail Making test Part B (P = 0.02) compared to younger HIV+ patients with dementia (n = 15). Age was associated with lower performance in tests of memory, executive functioning, and motor performance in older HIV+ individuals with and without cognitive impairment (total cohort), compared to younger HIV+ individuals. Among HIV+ patients with dementia, age may be associated with greater impairment in a test of executive functioning. These differences could be a result of advanced age itself or age-associated comorbidities such as coexisting cerebrovascular or neurodegenerative disease.
Effect of methylphenidate treatment on appetite and levels of leptin, ghrelin, adiponectin, and brain-derived neurotrophic factor in children and adolescents with attention deficit and hyperactivity disorder.

OBJECTIVES
We aimed to explore whether the use of methylphenidate relates leptin, ghrelin, adiponectin, and brain-derived neurotrophic factor (BDNF). In addition, the relationship between methylphenidate-related weight loss in attention deficit hyperactivity disorder (ADHD) patients and these biomolecules were evaluated.


METHODS
Thirty ADHD patients receiving methylphenidate and 20 healthy controls were included. Leptin, ghrelin, adiponectin, and BDNF levels were measured at baseline and after two-month treatment in both groups.


RESULTS
At baseline, leptin, ghrelin, adiponectin, and BDNF levels were similar in the ADHD and control groups. The most common adverse events occurring in the ADHD group after a 2-month treatment period included loss of appetite (70%) and weight loss (66.7%). A significant difference was found in body weight, BMI, and CGI scores of the ADHD patients after the treatment. While post-treatment ghrelin and adiponectin levels were significantly higher in the ADHD group, BDNF level was significantly lower. Post-treatment decrease in leptin levels was not significant.


CONCLUSIONS
Leptin and BDNF were not associated with poor appetite and/or weight loss due to methylphenidate treatment. However, ghrelin and adiponectin might be biomolecules that play a role in underlying neurobiological mechanisms of methylphenidate-related appetite or weight loss.