LLukas22/scidocs huggingface dataset:
Multilingual Question/Answering: the DIOGENE System

This paper presents the DIOGENE question/answering system developed at ITCIrst. The system is based on a rather standard architecture which includes three components for question processing, search and answer extraction. Linguistic processing strongly relies on MULTIWORDNET, an extended version of the English WORDNET. The system has been designed to address two promising directions: multilingual question/answering and question/answering on the Web. The results obtained in the TREC-10 main task will be presented and discussed.
Biomedical Waste Management : An Infrastructural Survey of Hospitals.

BACKGROUND
The Ministry of Environment & Forests notified the Biomedical Waste (management & handling) Rules, 1998" (BMW Mgt) in July 1998. In accordance with the rules, every hospital generating BMW needs to set up requisite BMW treatment facilities on site or ensure requisite treatment of waste at common treatment facility. No untreated BMW shall be kept stored beyond a period of 48 hours. The cost of construction, operation and maintenance of system for managing BMW represents a significant part of overall budget of a hospital if the BMW rules have to be implemented in their true spirit. Two types of costs are required to be incurred by hospitals for BMW Mgt, internal and external. Internal cost is the cost for segregation, mutilation, disinfection, internal storage and transportation including hidden cost of protective equipment. External costs are off site transportation, treatment and final disposal.


METHODS
A study of hospitals was carried out from various sectors like Govt, Private, Charitable institutions etc. to assess the infrastructural requirement for BMW Mgt. Cost was worked out for a hospital where all the infrastructure as per each and every requirement of BMW rules had been implemented and then it was compared with other hospitals where hospitals have made compromises on each stage of BMW Mgt.


RESULTS
Capital cost incurred by benchmarked hospital of 1047 beds was Rs.3 lakh 59 thousand excluding cost of incinerator and hospital is incurring Rs. 656/- per day as recurring expenditure. Pune city has common regional facility for BMW final disposal. Facility is charging Rs.20 per kg of infectious waste. As on Dec 2001 there were 400 institutions including nursing homes, labs and blood banks which were registered.


CONCLUSION
After analyzing the results of study it was felt that there is an urgent need to standardize the infrastructural requirement so that hospitals following BMW rules strictly do not suffer additional costs.
[Procalcitonin and early-onset seizures: When do we offer a higher diagnostic yield?].

1. Certificación de Centros y Unidades Sanitarias. DG-06.02.01 Documento General de Certificación de Servicios (Rev. 5) 4 de febrero de 2014. Agencia de Calidad Sanitaria de Andalucía. Consejería de Igualdad, Salud y Políticas Sociales. Junta de Andalucía [accessed 1 September 2014]. Available: http://www.acsa.juntaandalucia.es:8080/opencms851/opencms/.content/galerias/ documentos/documentos-certificacion/Centros/Documento General de Certificacion de Servicios R6.pdf 2. Manual de estándares de Centros del Sistema Sanitario de Andalucía. ME 2 1 04. Agencia de Calidad Sanitaria de Andalucía. Consejería de Igualdad, Salud y Políticas Sociales. Junta de Andalucía [accessed 1 September 2014]. Available: http:// www.acsa.junta-andalucia.es/.content/galerias/documentos/ documentos-certificacion/Centros/Manual estandares centros sistema ME2 1 04.pdf 3. Proceso Asistencial Integrado Asma en la edad pediátrica. Consejería de Salud. 2003. Junta de Andalucía [accessed 1 September 2014]. Available en: http://www.csalud.junta-andalucia.es/ salud/export/sites/csalud/galerias/documentos/p 3 p 3 procesos asistenciales integrados/asma pediatrica/asma pediatrica sustituido.pdf 4. Antonio Pons Tubío et al. Proceso Asistencial Integrado Atención temprana. Seguimiento recién nacido de riesgo. Consejería de Salud. 2009. Junta de Andalucía [accessed 1 September 2014]. Available: http://www.csalud.junta-andalucia.es/salud/ export/sites/csalud/galerias/documentos/p 3 p 3 procesos asistenciales integrados/seguimiento/0 riesgo.pdf 5. Proceso Asistencial Integrado Otitis Media Consejería de Salud. 2002. Junta de Andalucía [accessed 1 September 2014]. Available: http://www.csalud.junta-andalucia.es/salud/ export/sites/csalud/galerias/documentos/p 3 p 3 procesos asistenciales integrados/otitis media/otitis media.pdf 6. Proceso Asistencial Integrado Amigdalectomíaadenoidectomía. Consejería de Salud. 2003. Junta de Andalucía [accessed 1 September 2014]. Available: http://www.csalud.juntaandalucia.es/salud/export/sites/csalud/galerias/documentos/ p 3 p 3 procesos asistenciales integrados/amigdalectomia/ amigdalectomia nuevo.pdf
Association of Aortic Stiffness With Left Ventricular Remodeling and Reduced Left Ventricular Function Measured by Magnetic Resonance Imaging: The Multi-Ethnic Study of Atherosclerosis.

BACKGROUND
This study sought to assess cross-sectional associations of aortic stiffness assessed by magnetic resonance imaging with left ventricular (LV) remodeling and myocardial deformation in the Multi-Ethnic Study of Atherosclerosis (MESA).


METHODS AND RESULTS
Aortic arch pulse wave velocity (PWV) was measured with phase contrast cine magnetic resonance imaging. LV circumferential strain (Ecc), torsion, and early diastolic strain rate were determined by tagged magnetic resonance imaging. Multivariable linear regression models were used to adjust for demographics and cardiovascular risk factors. Of 2093 participants, multivariable linear regression models demonstrated that higher arch PWV was associated with higher LV mass index (B=0.53 per 1 SD increase for log-transformed PWV, P<0.05) and LV mass to volume ratio (B=0.015, P<0.01), impaired LV ejection fraction (LVEF; B=-0.84; P<0.001), Ecc (B=0.55; P<0.001), torsion (B=-0.11; P<0.001), and early diastolic strain rate (B=-0.003; P<0.05). In sex stratified analysis, higher arch PWV was associated with higher MVR (B=0.02; P<0.05), impaired Ecc (B=0.60; P<0.001), and LVEF (B=-0.45; P<0.05), but with maintained torsion in women. Higher PWV was associated with impaired Ecc (B=0.49; P<0.001) and LVEF (B=-1.21; P<0.001), with lower torsion (B=-0.17; P<0.001) in men.


CONCLUSIONS
Higher arch PWV is associated with LV remodeling, and reduced LV systolic and diastolic function in a large multiethnic population. Greater aortic arch stiffness is associated with concentric LV remodeling and relatively preserved LVEF with maintained torsion in women, whereas greater aortic arch stiffness is associated with greater LV dysfunction demonstrated as impaired Ecc, torsion, and LVEF, with less concentric LV remodeling in men.
Polarized training has greater impact on key endurance variables than threshold, high intensity, or high volume training

UNLABELLED
ENDURANCE ATHLETES INTEGRATE FOUR CONDITIONING CONCEPTS IN THEIR TRAINING PROGRAMS: high-volume training (HVT), "threshold-training" (THR), high-intensity interval training (HIIT) and a combination of these aforementioned concepts known as polarized training (POL). The purpose of this study was to explore which of these four training concepts provides the greatest response on key components of endurance performance in well-trained endurance athletes.


METHODS
Forty eight runners, cyclists, triathletes, and cross-country skiers (peak oxygen uptake: (VO2peak): 62.6 ± 7.1 mL·min(-1)·kg(-1)) were randomly assigned to one of four groups performing over 9 weeks. An incremental test, work economy and a VO2peak tests were performed. Training intensity was heart rate controlled.


RESULTS
POL demonstrated the greatest increase in VO2peak (+6.8 ml·min·kg(-1) or 11.7%, P < 0.001), time to exhaustion during the ramp protocol (+17.4%, P < 0.001) and peak velocity/power (+5.1%, P < 0.01). Velocity/power at 4 mmol·L(-1) increased after POL (+8.1%, P < 0.01) and HIIT (+5.6%, P < 0.05). No differences in pre- to post-changes of work economy were found between the groups. Body mass was reduced by 3.7% (P < 0.001) following HIIT, with no changes in the other groups. With the exception of slight improvements in work economy in THR, both HVT and THR had no further effects on measured variables of endurance performance (P > 0.05).


CONCLUSION
POL resulted in the greatest improvements in most key variables of endurance performance in well-trained endurance athletes. THR or HVT did not lead to further improvements in performance related variables.
Walking up and down stairs carrying a human by a biped locomotor with parallel mechanism

This paper describes the means of tuning-up method of the walking parameters to go up and down stairs for a biped robot with leg mechanisms using Stewart platforms. It has been confirmed that the stroke range of use could be reduced by tuning up the waist yaw trajectory and preset ZMP trajectories for motion pattern generation. By using the developed method, a walking experiment involving movement up and down a stair with the rise of 250 mm and certain walking experiments ascending and descending stairs carrying a human were successfully completed. Through these experiments, the effectiveness of the proposed method was confirmed.
Phase 2 study of pre-excision single-dose intraoperative radiation therapy for early-stage breast cancers: six-year update with application of the ASTRO accelerated partial breast irradiation consensus statement criteria.

BACKGROUND
Intraoperative radiation therapy (IORT) allows delivery of high-dose radiation at the time of lumpectomy, potentially sparing adjuvant daily radiation. A phase 2 study of pre-excision IORT was performed for early-stage breast cancer.


METHODS
Patients ≥ 48 years of age with invasive ductal carcinoma, ≤ 3 cm, and clinically node-negative were eligible for this study, which was approved by institutional review board. Ultrasound was used to select electron energy and cone size to cover the tumor plus 1.5- to 2.0-cm lateral margins and 1-cm-deep margins (90% isodose). Fifteen Gy was delivered with a Mobetron irradiator, and immediate needle-localized partial mastectomy followed. Local event results were updated using the Kaplan-Meier method.


RESULTS
A total of 53 patients received IORT alone. Median age was 63 years, and median tumor size was 1.2 cm. Of these, 81% were positive for estrogen receptor or progesterone receptor, 11% were positive for human epidermal growth factor receptor 2, and 15% were triple-negative. Also, 42%, 49%, and 9% would have fallen into the Suitable, Cautionary, and Unsuitable groups, respectively, of the American Society of Therapeutic Radiation Oncology consensus statement for accelerated partial breast irradiation. Median follow-up was 69 months. Ipsilateral events occurred in 8 of 53 patients. The 6-year actuarial rate of ipsilateral events was 15% (95% confidence interval = 7%-29%). The crude event rate for Suitable and Cautionary groups was 1 of 22 (5%) and 7 of 26 (27%), respectively. Overall survival was 94.4%, and breast cancer-specific survival was 100%.


CONCLUSIONS
The rate of local events in this study is a matter of concern, especially in the Cautionary group. On the basis of these findings, pre-excision IORT, as delivered in this study, may not provide adequate local control for less favorable early-stage breast cancers.
Mapping health assessment questionnaire disability index (HAQ-DI) score, pain visual analog scale (VAS), and disease activity score in 28 joints (DAS28) onto the EuroQol-5D (EQ-5D) utility score with the KORean Observational study Network for Arthritis (KORONA) registry data

The aim of this study was to estimate the mapping model for EuroQol-5D (EQ-5D) utility values using the health assessment questionnaire disability index (HAQ-DI), pain visual analog scale (VAS), and disease activity score in 28 joints (DAS28) in a large, nationwide cohort of rheumatoid arthritis (RA) patients in Korea. The KORean Observational study Network for Arthritis (KORONA) registry data on 3557 patients with RA were used. Data were randomly divided into a modeling set (80 % of the data) and a validation set (20 % of the data). The ordinary least squares (OLS), Tobit, and two-part model methods were employed to construct a model to map to the EQ-5D index. Using a combination of HAQ-DI, pain VAS, and DAS28, four model versions were examined. To evaluate the predictive accuracy of the models, the root-mean-square error (RMSE) and mean absolute error (MAE) were calculated using the validation dataset. A model that included HAQ-DI, pain VAS, and DAS28 produced the highest adjusted R 2 as well as the lowest Akaike information criterion, RMSE, and MAE, regardless of the statistical methods used in modeling set. The mapping equation of the OLS method is given as EQ-5D = 0.95−0.21 × HAQ-DI−0.24 × pain VAS/100–0.01 × DAS28 (adjusted R 2 = 57.6 %, RMSE = 0.1654 and MAE = 0.1222). Also in the validation set, the RMSE and MAE were shown to be the smallest. The model with HAQ-DI, pain VAS, and DAS28 showed the best performance, and this mapping model enabled the estimation of an EQ-5D value for RA patients in whom utility values have not been measured.
Formation of topologically closed packed phases within CMSX-4 single crystals produced by additive manufacturing

Abstract The homogeneity of single crystals produced by additive manufacturing (AM) is much higher than that of single crystals produced by the standard investment casting process. Aim of this paper is to investigate the influence of this homogeneity on the formation kinetics of topologically closed packed (TCP) phases. CMSX-4 single crystals produced by selective electron beam melting and investment casting are homogenized and annealed at 870 °C and 1050 °C for up to 480 h. The formation kinetics of TCP phase formation is analyzed by electron microscopy.
Nomogram of nasal bone length at 11-14 week of gestation in Indian women and their follow up till delivery

Background: The measurement of nasal bone length (NBL) according to gestational age and setting nomogram helps to ascertain NB hypoplasia. This can be used for early detection of trisomy 21 and other chromosomal abnormalities in low risk population. The objective of the study was to obtain nomogram of fetal nasal bone length at 11-14 weeks gestation with known prognosis pregnancies. Methods: A single centre, prospective crosses sectional study. Nasal bone length of 323 choromosomal and structural normal fetuses at 11-14 weeks gestation were measured by transabdominal ultrasonography, prospectively. The correlation between nasal bone and other biometric parameters was assessed by regression analysis and average±SD of nasal bone lengths were measured. Results: Fetal NB length (NBL) was visualized and measured in 281 patients (94.29%). Mean NB length was 3.07 mm, ranged between 1.60 mm to 4.6 mm and SD was 0.534. A linear growth pattern was observed between nasal bone and fetal biometric parameters. The significant correlation were found between the nasal bone and biparietal diameter (BPD) [NBL= 2.184+0.046 x BPD (r= 0.286, p value 0.000)], femoral length (FL) [NBL= 2.234+0.095xFL (r= 0.369, p value 0.000)] and crown-rump length (CRL) [NBL= 2.205+0.014 x CRL (r= 0.291, p value 0.000)]. Prenasal thickness (PT) increased linearly with CRL and POG. [PT= 1.081+0.006 x CRL (r= 0.16, p value= 0.02) and PT= 0.430+0.08 x POG (r= 0.15, p value= 0.028)]. Conclusions: Measurement of the nasal bone length at 11-14 weeks of gestation shows a linear growth pattern according to other biometric parameters of fetuses. Nomogram of nasal bone length was performed for early detection of trisomy 21 and other chromosomal abnormalities at low risk population.
Prophylactic Antiepileptic Drug Use and Outcome in the Ethnic/Racial Variations of Intracerebral Hemorrhage Study.

BACKGROUND AND PURPOSE
The role of antiepileptic drug (AED) prophylaxis after intracerebral hemorrhage (ICH) remains unclear. This analysis describes prevalence of prophylactic AED use, as directed by treating clinicians, in a prospective ICH cohort and tests the hypothesis that it is associated with poor outcome.


METHODS
Analysis included 744 patients with ICH enrolled in the Ethnic/Racial Variations of Intracerebral Hemorrhage (ERICH) study before November 2012. Baseline clinical characteristics and AED use were recorded in standardized fashion. ICH location and volume were recorded from baseline neuroimaging. We analyzed differences in patient characteristics by AED prophylaxis, and we used logistic regression to test whether AED prophylaxis was associated with poor outcome. The primary outcome was 3-month modified Rankin Scale score, with 4 to 6 considered poor outcome.


RESULTS
AEDs were used for prophylaxis in 289 (39%) of the 744 subjects; of these, levetiracetam was used in 89%. Patients with lobar ICH, craniotomy, or larger hematomas were more likely to receive prophlyaxis. Although prophylactic AED use was associated with poor outcome in an unadjusted model (odds ratio, 1.40; 95% confidence interval, 1.04-1.88; P=0.03), this association was no longer significant after adjusting for clinical and demographic characteristics (odds ratio, 1.11; 95% confidence interval, 0.74-1.65; P=0.62).


CONCLUSIONS
We found no evidence that AED use (predominantly levetiracetam) is independently associated with poor outcome. A prospective study is required to assess for a more modest effect of AED use on outcome after ICH.
Investigating learners' attitudes toward virtual reality learning environments: Based on a constructivist approach

The use of animation and multimedia for learning is now further extended by the provision of entire Virtual Reality Learning Environments (VRLE). This highlights a shift in Web-based learning from a conventional multimedia to a more immersive, interactive, intuitive and exciting VR learning environment. VRLEs simulate the real world through the application of 3D models that initiates interaction, immersion and trigger the imagination of the learner. The question of good pedagogy and use of technology innovations comes into focus once again. Educators attempt to find theoretical guidelines or instructional principles that could assist them in developing and applying a novel VR learning environment intelligently. This paper introduces the educational use of Web-based 3D technologies and highlights in particular VR features. It then identifies constructivist learning as the pedagogical engine driving the construction of VRLE and discusses five constructivist learning approaches. Furthermore, the authors provide two case studies to investigate VRLEs for learning purposes. The authors conclude with formulating some guidelines for the effective use of VRLEs, including discussion of the limitations and implications for the future study of VRLEs. 2010 Elsevier Ltd. All rights reserved.
Phase II study of gemcitabine and cisplatin as first-line chemotherapy in inoperable biliary tract carcinoma.

OBJECTIVES
The prognosis for patients with unresectable biliary tract cancer is poor and existing chemotherapy is relatively ineffective. Therefore, a need exists for new, effective chemotherapeutic regimens. The aim of this study was to determine the efficacy and safety profile of gemcitabine plus cisplatin in patients with unresectable biliary tract cancer (cholangiocarcinoma) and gall bladder cancer.


METHODS
From December 2000 to July 2002, 43 patients received gemcitabine 1250 mg/m(2) in a 30-min i.v. infusion on d1, 8 and cisplatin 75 mg/m(2) in a 2-h i.v. infusion on d1 (with appropriate hydration), every 3 weeks. ELIGIBILITY: Normal hematologic parameters and creatinine levels; serum bilirubin < 5 mg/dl.


RESULTS
Forty-three patients enrolled; 40 were assessable (three patients were not assessable due to incomplete treatment; they chose to discontinue chemotherapy after the first cycle). There were 23 males and 17 females, median age 50 years (range 31-69), median Karnofsky PS 80%. Tumor types: cholangiocarcinoma (39), gall bladder cancer (1). Median number of chemotherapy courses was four (range 1-8). Overall response rate was 27.5% (PR in 11 pts), with 32.5% SD and/or minor response. Median survival time was 36 weeks. Grade 3 hematologic toxicity: anemia (4.33%), leukopenia (1.73%). Non-hematologic toxicity (i.e. rash, nausea, vomiting, neuropathy and myalgia) ranged from mild to moderate.


CONCLUSIONS
Gemcitabine plus cisplatin is active in biliary tract carcinoma. These data warrant further investigation of single-agent gemcitabine versus gemcitabine plus cisplatin or its derivative, i.e. oxaliplatin.
The influence of extro/introversion on the intention to pay for social networking sites

Although social networking sites (SNSs) have attracted increased attention and members in recent years, there has been little research on it: particularly on how a users’ extroversion or introversion can affect their intention to pay for these services and what other factors might influence them. We therefore proposed and tested a model that measured the users’ value and satisfaction perspectives by examining the influence of these factors in an empirical survey of 288 SNS members. At the same time, the differences due to their psychological state were explored. The causal model was validated using PLSGraph 3.0; six out of eight study hypotheses were supported. The results indicated that perceived value significantly influenced the intention to pay SNS subscription fees while satisfaction did not. Moreover, extroverts thought more highly of the social value of the SNS, while introverts placed more importance on its emotional and price value. The implications of these findings are discussed. Crown Copyright 2010 Published by Elsevier B.V. All rights reserved.
Independent wheel torque control of 4WD electric vehicle for differential drive assisted steering

In-wheel motors have tremendous potential to create an advanced all-wheel drive system. In this paper, a novel power assisted steering technology and its torque distribution control system were proposed, due to the independent driving characteristics of four-wheel-independent-drive electric vehicle. The first part of this study deals with the full description of the basic theory of differential drive assisted steering system. After that, 4-wheel-drive (4WD) electric vehicle dynamics model as well as driver model were built. Furthermore, the differential drive assisted steering control system, as well as the drive torque distribution and compensation control system, was also presented. Therein, the proportional–integral (PI) feedback control loop was employed to track the reference steering effort by controlling the drive torque distribution between the two sides wheels of the front axle. After that, the direct yaw moment control subsystem and the traction control subsystem were introduced, which were both employed to make the differential drive assisted steering work as well as wished. Finally, the open-loop and closed-loop simulation for validation were performed. The results verified that, the proposed differential drive torque assisted steering system cannot only reduce the steering efforts significantly, as well as ensure a stiffer steering feel at high vehicle speed and improve the returnability of the vehicle, but also keep the lateral stability of the vehicle. 2010 Elsevier Ltd. All rights reserved.