LLukas22/scidocs huggingface dataset:
DISTANCE BASED ENERGY EFFICIENT SELECTION OF NODES TO CLUSTER HEAD IN HOMOGENEOUS WIRELESS SENSOR NETWORKS

Wireless sensor networks (WSN) provide the availability of small and low-cost sensor nodes with capability of detecting, observing and monitoring the environment, along with data processing and communication. These sensor nodes have limited transmission range, processing and storage capabilities as well as their energy resources. Routing protocols for wireless sensor networks are responsible for maintaining the energy efficient paths in the network and have to ensure extended network lifetime. In this paper, we propose and analyze a new approach of cluster head selection by a homogeneous sensor node (having same initial energy) in wireless sensor network, which involves choosing the cluster head which lies closest to the midpoint of the base station and the sensor node. Our proposed routing algorithm is related with energy and distance factors of each nodes. This scheme is then compared with the traditional LEACH protocol which involves selecting the cluster head which is nearest to the particular node. We conclude that the proposed protocol effectively extends the network lifetime with less consumption of energy in the network.
Proton structure function at smallQ2

A fit is made to the data for the proton structure function up toQ2=10 GeV2, including the real γp total cross-section. It is economical and simple, and its form is motivated by physical principles. It is extrapolated down to very small values ofx. Data for the ratio νW2n/νW2p are also fitted.
Internet Pathways in Suicidality: A Review of the Evidence

The general aim of this study was to review the scientific literature concerning the Internet and suicidality and to examine the different pathways by which suicidal risks and prevention efforts are facilitated through the Internet. An online literature search was conducted using the MEDLINE and Google Scholar databases. The main themes that were investigated included pathological Internet use and suicidality, pro-suicide websites, suicide pacts on the Internet, and suicide prevention via the Internet. Articles were screened based on the titles and abstracts reporting on the themes of interest. Thereafter, articles were selected based on scientific relevance of the study, and included for full text assessment. The results illustrated that specific Internet pathways increased the risk for suicidal behaviours, particularly in adolescents and young people. Several studies found significant correlations between pathological Internet use and suicidal ideation and non-suicidal self-injury. Pro-suicide websites and online suicide pacts were observed as high-risk factors for facilitating suicidal behaviours, particularly among isolated and susceptible individuals. Conversely, the evidence also showed that the Internet could be an effective tool for suicide prevention, especially for socially-isolated and vulnerable individuals, who might otherwise be unreachable. It is this paradox that accentuates the need for further research in this field.
Severity of cognitive impairment as a prognostic factor for mortality and functional recovery of geriatric patients with hip fracture.

AIM
To identify how the severity of dementia influences functional recovery and mortality in elderly patients hospitalized for hip fracture.


METHODS
An observational retrospective study of 1258 patients aged older than 69 years and diagnosed with hip fracture who received care within an orthogeriatrics unit from 2004 to 2008 was carried out. During a 12-month follow-up period, functional recovery and mortality outcomes were measured.


RESULTS
Dementia was present in 383 (28.1%) patients: it was mild in 183 (48%), moderate in 102 (26.5%) and severe in 98 (25.5%). Compared with patients with preserved cognitive status, patients with dementia had the following statistically significant differences (means [standard deviation] or percentage): older age (preserved, 82.29 years [6.5 years]; mild, 83.63 years [6.1 years]; moderate, 83.47 years [5.9 years]; severe, 84.46 years [6.1 years]; P < 0.001); lower Barthel Index (89.7 [21.6], 72.7 [24.6], 58.9 [28.6], 38.0 [28.1]; P < 0.001); delirium (11.7%, 25.6%, 37.6%, 44.7%; P < 0.001); less ambulation at 6 months postdischarge (83.9%, 72.8%, 56.9%, 41.7%; P < 0.001); and higher mortality at discharge (4%, 5.7%, 8.2%, 10.6%; P < 0.001) and 12 months after discharge (21.2%, 32.3%, 46.3%, 53.5%; P < 0.001). Patients with severe dementia had lower probability of functional recovery at discharge (OR 0.272, 95% CI 0.140-0.526, P < 0.001) and 6 months after discharge (OR 0.439, 95% CI 0.197-0.979, P = 0.04), as well as a greater probability of dying (HR 1.640, 95% CI 1.020-2.635, P = 0.04).


CONCLUSIONS
We observed higher 12-month mortality and less functional recovery with increasing severity of dementia.
The Growing Hierarchical Self-Organizing Map

In this paper we present the growing hierarchical self-organizing map . This dynamically growing neural network model evolves into a hierarchical structure according to the requirements of the input data during an unsupervised training process. We demonstrate the benefits of this novel neural network model by organizing a real-world document collection according to their similarities.
Data-driven agent-based modeling, with application to rooftop solar adoption

Agent-based modeling is commonly used for studying complex system properties emergent from interactions among agents. However, agent-based models are often not developed explicitly for prediction, and are generally not validated as such. We therefore present a novel data-driven agent-based modeling framework, in which individual behavior model is learned by machine learning techniques, deployed in multi-agent systems and validated using a holdout sequence of collective adoption decisions. We apply the framework to forecasting individual and aggregate residential rooftop solar adoption in San Diego county and demonstrate that the resulting agent-based model successfully forecasts solar adoption trends and provides a meaningful quantification of uncertainty about its predictions. Meanwhile, we construct a second agent-based model, with its parameters calibrated based on mean square error of its fitted aggregate adoption to the ground truth. Our result suggests that our data-driven agent-based approach based on maximum likelihood estimation substantially outperforms the calibrated agent-based model. Seeing advantage over the state-of-the-art modeling methodology, we utilize our agent-based model to aid search for potentially better incentive structures aimed at spurring more solar adoption. Although the impact of solar subsidies is rather limited in our case, our study still reveals that a simple heuristic search algorithm can lead to more effective incentive plans than the current solar subsidies in San Diego County and a previously explored structure. Finally, we examine an exclusive class of policies that gives away free systems to low-income households, which are shown significantly more efficacious than any incentive-based policies we have analyzed to date.
STRATEGIC LEADERSHIP AND EXECUTIVE INNOVATION INFLUENCE : AN INTERNATIONAL MULTI-CLUSTER COMPARATIVE STUDY

This study investigates the relationship of strategic leadership behaviors with executive innovation influence and the moderating effects of top management team (TMT)’s tenure heterogeneity and social culture on that relationship. Using survey data from six countries comprising three social cultures, strategic leadership behaviors were found to have a strong positive relationship with executive influence on both product–market and administrative innovations. In addition, TMT tenure heterogeneity moderated the relationship of strategic leadership behaviors with executive innovation influence for both types of innovation, while social culture moderated that relationship only in the case of administrative innovation. Copyright  2005 John Wiley & Sons, Ltd.
Vertebral fracture or vertebral deformity?

In our recently completed sodium fluoride (NaF) clinical trial [1] we observed that only about 25% of vertebral deformities, documented by change in vertebral morphometry on radiographs, were associated with corresponding areas of increased isotope uptake on radionuclide bone scans. This was an unexpected finding. In the initial trial design, we had anticipated that the scan would be more sensitive than radiographs and would detect "fractures" that were not documented radiographically. The study format included annual radiographs and semiannual scans in the hope that a higher vertebral fracture rate by scintigraphy would increase the power of the study. The failure of the bone scan in this regard, which was independent of treatment assignment (placebo or NaF), has several plausible explanations, the most compelling of which is that changes in vertebral morphometry in spinal osteoporosis can occur by mechanisms other than fracture. If correct, that hypothesis would have major impact on epidemiologic and clinical studies of spinal osteoporosis. Most fractures in the appendicular skeleton are all-ornone events and the expected outcome is that the affected bone will heal completely with full restoration of original shape and function. Every attempt is made to avoid permanent postfracture deformity of a long bone. Postfracture deformity is easy to recognize clinically and radiographically when the involved bone is anywhere but in the spine, and there is rarely any doubt as to the cause of the deformity. In sharp contrast, fractures of the vertebral bodies are graded in their severity, and permanent deformity is the expected outcome. It is accepted that certain vertebral deformities develop by mechanisms other than fracture (e.g., Scheuermann's juvenile kyphosis). Yet, most clinicians and investigators in this field operate under the assumption that a change in vertebral morphology m u s t represent fracture occurrence. The findings of our fluoride trial raise the possibility that not every new vertebral deformity is the result of a fracture. Harrison et al. [2] reported recently that isolated midthoracic vertebral deformity was not associated with significant osteopenia and cannot be regarded as diagnostic of osteoporotic fracture, confirming an earlier observation of Nordin et al. [3]. This distinction between fracture and deformity is crucial for the proper conduct of cross-sectional epidemiologic studies in spinal osteoporosis. This may also be the case for longitudinal studies including therapeutic trials in this disease, and affects the choice of methods to be employed. The prevalence of vertebral "fractures" in a population actually represents the prevalence of vertebral deformity which includes some unknown proportion of true fractures. Unless an investigator can confirm by history and review of medical records that a particular episode of acute back pain
Tranexamic acid for hyperacute primary IntraCerebral Haemorrhage (TICH-2): an international randomised, placebo-controlled, phase 3 superiority trial

BACKGROUND
Tranexamic acid can prevent death due to bleeding after trauma and post-partum haemorrhage. We aimed to assess whether tranexamic acid reduces haematoma expansion and improves outcome in adults with stroke due to intracerebral haemorrhage.


METHODS
We did an international, randomised placebo-controlled trial in adults with intracerebral haemorrhage from acute stroke units at 124 hospital sites in 12 countries. Participants were randomly assigned (1:1) to receive 1 g intravenous tranexamic acid bolus followed by an 8 h infusion of 1 g tranexamic acid or a matching placebo, within 8 h of symptom onset. Randomisation was done centrally in real time via a secure website, with stratification by country and minimisation on key prognostic factors. Treatment allocation was concealed from patients, outcome assessors, and all other health-care workers involved in the trial. The primary outcome was functional status at day 90, measured by shift in the modified Rankin Scale, using ordinal logistic regression with adjustment for stratification and minimisation criteria. All analyses were done on an intention-to-treat basis. This trial is registered with the ISRCTN registry, number ISRCTN93732214.


FINDINGS
We recruited 2325 participants between March 1, 2013, and Sept 30, 2017. 1161 patients received tranexamic acid and 1164 received placebo; the treatment groups were well balanced at baseline. The primary outcome was assessed for 2307 (99%) participants. The primary outcome, functional status at day 90, did not differ significantly between the groups (adjusted odds ratio [aOR] 0·88, 95% CI 0·76-1·03, p=0·11). Although there were fewer deaths by day 7 in the tranexamic acid group (101 [9%] deaths in the tranexamic acid group vs 123 [11%] deaths in the placebo group; aOR 0·73, 0·53-0·99, p=0·0406), there was no difference in case fatality at 90 days (250 [22%] vs 249 [21%]; adjusted hazard ratio 0·92, 95% CI 0·77-1·10, p=0·37). Fewer patients had serious adverse events after tranexamic acid than after placebo by days 2 (379 [33%] patients vs 417 [36%] patients), 7 (456 [39%] vs 497 [43%]), and 90 (521 [45%] vs 556 [48%]).


INTERPRETATION
Functional status 90 days after intracerebral haemorrhage did not differ significantly between patients who received tranexamic acid and those who received placebo, despite a reduction in early deaths and serious adverse events. Larger randomised trials are needed to confirm or refute a clinically significant treatment effect.


FUNDING
National Institute of Health Research Health Technology Assessment Programme and Swiss Heart Foundation.
Efficacy and safety study of arbaclofen placarbil in patients with spasticity due to spinal cord injury

Study design:Randomized, double-blind, placebo-controlled, two-period crossover.Objectives:To evaluate the efficacy and safety of arbaclofen placarbil (AP) in patients with spasticity secondary to spinal cord injury (SCI).Setting:United States and Canada.Methods:Patients received extended-release AP tablets 10, 20 or 30 mg every 12 h in one of two AP/placebo sequences, with 26 days of each treatment. The primary analysis compared Ashworth scale assessments of muscle tone between AP and placebo for the muscle group with maximum baseline Ashworth score. Secondary endpoints included a patient-rated Severity of Spasticity Scale.Results:In the primary analysis, AP significantly improved Ashworth scores compared with placebo over the dosing interval: least-squares mean reduction versus placebo was 0.60 for AP 20 mg (P=0.0059) and 0.88 for AP 30 mg (P=0.0007). The difference was significant for the pre-morning dose time point, 12 h after the prior evening dose, indicating that efficacy was maintained throughout the dosing interval. Treatment differences for AP 10 mg versus placebo were not significant. Severity of Spasticity ratings were significantly reduced for the combined 20/30-mg group versus placebo (P=0.018). No statistically significant differences between AP and placebo were observed for muscle strength. AP-related AEs were generally mild to moderate in intensity, and none led to early withdrawal or were serious.Conclusion:AP was well tolerated at all investigated dosages and, when administered at doses of 20 or 30 mg twice daily, was efficacious in reducing spasticity due to SCI.
Constipation: understanding mechanisms and management.

Constipation is a frequently diagnosed gastrointestinal disorder. Symptoms of constipation are common, with the greatest prevalence in the elderly. Evaluation of constipation begins with a detailed medical history and a focused anorectal examination. Diagnostic testing for constipation is not routinely recommended in the initial evaluation in the absence of alarm signs. Key self-management strategies include increased exercise, a high-fiber diet, and toilet training. High-fiber diets can worsen symptoms in some patients who have chronic constipation. Biofeedback is an effective treatment option for patients who have constipation caused by outlet obstruction defecation. A variety of medications are available to remedy constipation.
Acute dislocations of the distal radioulnar joint and distal ulna fractures.

This article reviews acute dislocations of the distal radioulnar joint (DRUJ) and distal ulna fractures. Acute dislocations can occur in isolation or in association with a fracture to the distal radius, radial metadiaphysis (Galeazzi fracture), or radial head (Essex-Lopresti injury). Distal ulna fractures may occur in isolation or in combination with a distal radius fracture. Both injury patterns are associated with high energy. Outcomes are predicated on anatomic reduction and restoration of the stability of the DRUJ.
Factoring polynomials over global fields I

In this paper we present a generic algorithm for factoring polynomials over global fields F. As efficient implementations of that algorithm for number fields and function fields differ substantially, these cases will be treated separately. Complexity issues and implementations will be discussed in part II which also contains illustrative examples.
Similar evolution of hepatitis B virus quasispecies in patients with incomplete adefovir response receiving tenofovir/emtricitabine combination or tenofovir monotherapy.

BACKGROUND & AIMS
Adefovir (ADV) resistance mutations induce low-level cross-resistance to tenofovir in vitro. Our aim was to compare viral kinetics, nucleos(t)ide analog resistance mutations, and quasispecies (QS) evolution during therapy with tenofovir disoproxil fumarate (TDF) or emtricitabine + TDF (FTC/TDF) in selected patients with incomplete ADV responses.


METHODS
Patients with chronic hepatitis B and incomplete response to ADV were randomized in a double-blind trial of TDF vs. FTC/TDF. Extensive analysis of QS evolution was performed in 17 patients through 48 weeks of treatment.


RESULTS
At week 24, 48% of patients (9/17) achieved HBV DNA undetectability (<69 IU/ml) with no difference between treatment groups. ADV and/or LAM resistance mutations were detected in all 17 patients at baseline and in 5/6 analyzable patients at week 48. A total of 1224 reverse transcriptase clones were analyzed. Clonal analysis revealed no significant difference at baseline in QS complexity or diversity between treatment groups. There was a trend in both treatment groups for an increase in QS complexity at week 12, followed by a decrease in complexity and diversity by week 48. Analysis of individual patients showed no consistent selection/accumulation of specific viral resistance patterns during treatment, but at week 48, mutations at rtA181 persisted in 4 patients.


CONCLUSIONS
TDF or FTC/TDF demonstrated strong viral suppression in patients with an incomplete response to ADV and no significant selective pressure on pre-existing ADV or LAM resistant strains. TDF monotherapy and FTC/TDF combination therapy had a comparable impact on QS evolution.
Knowing the price of everything? Exploring the impact of increased procurement professional involvement on management consultancy purchasing

Abstract Much of the estimated $554 billion annual expenditure on management consultancy services is accounted for by projects with a direct link to client profitability. As such, it is critical for clients (and arguably the wider economy) that the purchase process for such services is managed effectively. For many within the management consultancy literature, this requires close, bilateral buy-side service end-user/supplier engagement. In recent years, however, this bilateral engagement has been modified by a significant increase in procurement professional involvement. This has caused concern within the management consultancy literature as it is believed it will inevitably lead to a cost-focused approach that disrupts close end-user/supplier engagement and causes sub-standard service outcomes. In this paper, we explore, via qualitative research, whether this concern is justified. In the event, the analysis suggested partial justification. However, examples of positive procurement involvement were also reported, suggesting that existing models and assumptions within the management consultancy literature regarding the impact of increased procurement involvement require modification.
Changing Views about ‘Osteoporoses’ (a 1998 Overview)

Recent realizations have begun to change how ‘osteoporoses’ are diagnosed, managed and studied. This article explains the nature and basis of some resulting controversies, chiefly for clinicians who manage such patients but do not participate in resolving those controversies. Currently the size of a bone ‘mass’ deficit serves to diagnose ‘osteoporosis’, but recently clarified physiology suggests at least three different kinds of osteoporosis could occur in people with identical bone ‘mass’ deficits. Indeed, they do occur. (a) In one kind, people have less bone than ‘normal’ but no bone problems unless they sustain injuries. Most of their resulting fractures, usually from falls, affect extremity bones. This condition can affect children, men and women. (b) In a second kind an osteopenia exists in which voluntary physical activities (not injuries) cause spontaneous fractures and/or bone pain, mainly in the spine, more often in women than men and seldom in children (osteogenesis imperfecta excepted). (c) A third kind combines features of the first two. As for the physiology involved in those affections, bone modeling can increase bone strength and ‘mass’, while BMU (Bone Multicellular Unit)-based bone remodeling can reduce them. Mainly bone strains control those two activities and muscles cause the largest strains, so muscle strength should strongly influence bone modeling, remodeling, strength and ‘mass’. If so chronic muscle weakness should usually cause an osteopenia and weakened bones. Excessive amounts of fatigue damage or microdamage can also weaken bones. From that physiology one could argue that chiefly chronic muscle weakness instead of an intrinsic bone disorder would cause (a), while intrinsic but still enigmatic modeling and remodeling disorders would cause (b), and (c) could combine features of both conditions. If so, these ideas could have significant effects on the future criteria used to diagnose osteoporoses and osteopenias, on how they are studied in the clinic and laboratory, and on how they are prevented or, if they occur, are managed.
Social Media Engagement Theory: Exploring the Influence of User Engagement on Social Media Usage

Business models that rely on social media and user-generated content have shifted from the more traditional business model, where value for the organization is derived from the one-way delivery of products and/or services, to the provision of intangible value based on user engagement. This research builds a model that hypothesizes that the user experiences from social interactions among users, operationalized as personalization, transparency, access to social resources, critical mass of social acquaintances, and risk, as well as with the technical features of the social media platform, operationalized as the completeness, flexibility, integration, and evolvability, influence user engagement and subsequent usage behavior. Using survey responses from 408 social media users, findings suggest that both social and technical factors impact user engagement and ultimately usage with additional direct impacts on usage by perceptions of the critical mass of social acquaintances and risk. KEywORdS Social Interactions, Social Media, Social Networking, Technical Features, Use, User Engagement, User Experience