LLukas22/scidocs huggingface dataset:
Participation in Sport and Moral Functioning: Does Ego Orientation Mediate Their Relationship?

This study examined whether participation in contact sports influences moral functioning within the sport context, and whether these effects are mediated by ego orientation; the role of task orientation on moral functioning was also examined. Participants ( N = 221) were college athletes participating in basketball, soccer, field hockey, and rugby. They completed questionnaires assessing sport participation, goal orientations, moral functioning, and social desirability. Structural equation modeling analysis indicated that participation in contact sports positively predicted ego orientation, which in turn predicted low levels of moral functioning. The direct effects of sport participation on moral functioning became nonsignificant in the presence of ego orientation, indicating that the latter construct mediates the relationship between the first two variables. Task orientation corresponded to high levels of moral functioning. These findings help us further understand the processes operating in contact sports and are discussed in terms of their implications for eliminating unsportspersonlike conduct from the sport context.
Data Mining Techniques: To Predict and Resolve Breast Cancer Survivability

Breast cancer is one of the deadliest disease, is the most common of all cancers and is the leading cause of cancer deaths in women worldwide, accounting for >1.6% of deaths and case fatality rates are highest in low-resource countries. The breast cancer risks are broadly classified into modifiable and non –modifiable factors. The non modifiable risk factors are age, gender, number of first degree relatives suffering from breast cancer, menstrual history, age at menarche and age at menopause. While the modifiable risk factors are BMI, age at first child birth, number of children, duration of breast feeding, alcohol, diet and number of abortions. This paper presents a diagnosis system for detecting breast cancer based on RepTree, RBF Network and Simple Logistic. In test stage, 10-fold cross validation method was applied to the University Medical Centre, Institute of Oncology, Ljubljana, Yugoslavia database to evaluate the proposed system performances. The correct classification rate of proposed system is 74.5%. This research demonstrated that the Simple Logistic can be used for reducing the dimension of feature space and proposed Rep Tree and RBF Network model can be used to obtain fast automatic diagnostic systems for other diseases. Keywords— Breast cancer survivability; Rep Tree; RBF Network; Simple Logistic; Diagnostic systems Full Text: http://www.ijcsmc.com/docs/papers/January2014/V3I1201402.pdf
Exploring the behaviour of base classifiers in credit scoring ensembles

Many techniques have been proposed for credit risk assessment, from statistical models to artificial intelligence methods. During the last few years, different approaches to classifier ensembles have successfully been applied to credit scoring problems, demonstrating to be more accurate than single prediction models. However, it is still a question what base classifiers should be employed in each ensemble in order to achieve the highest performance. Accordingly, the present paper evaluates the performance of seven individual prediction techniques when used as members of five different ensemble methods. The ultimate aim of this study is to suggest appropriate classifiers for each ensemble approach in the context of credit scoring. The experimental results and statistical tests show that the C4.5 decision tree constitutes the best solution for most ensemble methods, closely followed by the multilayer perceptron neural network and logistic regression, whereas the nearest neighbour and the naive Bayes classifiers appear to be significantly the worst. 2012 Elsevier Ltd. All rights reserved.
Moses: Open Source Toolkit for Statistical Machine Translation

We describe an open-source toolkit for statistical machine translation whose novel contributions are (a) support for linguistically motivated factors, (b) confusion network decoding, and (c) efficient data formats for translation models and language models. In addition to the SMT decoder, the toolkit also includes a wide variety of tools for training, tuning and applying the system to many translation tasks.
Botulinum Toxin for the Treatment of Gummy Smile

Materials and methods: An experimental in vivo study was conducted at a dermatology clinic in Riyadh in January 2016. The study included 23 female patients who ranged from 20 to 50 years and were treated with Botox injections due to excessive maxillary gingival display. The patients with short clinical crowns or long maxilla, those who were pregnant or breastfeeding, and patients with neuromuscular disorders were excluded. Patients received Botox type I, injected 3 mm lateral to the alar-fascial groove at the level of the nostril opening at the insertion of the levator labii superioris alaeque nasi muscle. Photos were taken of the patient’s smile before and after the treatment and were then uploaded to the SketchUp program to calculate improvements in gingival display. The distance from the lower margin of the upper lip to the gingival margin was calculated preand posttreatment. The amount of improvement was calculated as (pre-Botox treatment – post-Botox treatment/pre-Botox treatment × 100). The mean percentage of the total improvement was analyzed.
Aligning architecture knowledge management with Scrum

Combining agile project management approaches such as Scrum and software architecture related work has been found problematic. In this paper, we propose several models to align architecture knowledge management with Scrum, based on different architecture work practices in Scrum identified in the industry. The proposed models exploit an architectural knowledge base with a capability to generate architectural documents, and a decision-based architecture evaluation method.
Two Minus-C odorant binding proteins from Helicoverpa armigera display higher ligand binding affinity at acidic pH than neutral pH.

Odorant-binding proteins (OBPs), widely and abundantly expressed in insect olfactory organs, are important for insect olfaction. In this study, two novel Minus-C OBP genes (HarmOBP17 and HarmOBP18) were characterized from the cotton bollworm, Helicoverpa armigera, one of the most important pests in cotton and other crops. Quantitative RT-PCR results indicate that the expression levels of the two genes differed greatly in regard to developmental stages, tissues, and genders. Binding properties of the two OBPs with plant volatiles were investigated at different pH levels using a competitive binding assay. Both OBPs displayed the highest binding affinities (Ki<13 μM) with Beta-ionone among the 85 tested compounds. Surprisingly, the two OBPs (HarmOBP17 in particular) displayed higher binding at pH 5.0 than at pH 7.4 and 10.0. This is the first reported Lepidopteran OBPs showing a contrary pH-dependent ligand binding behavior to other OBPs, implying a different mechanism of ligand binding and release. In addition, binding assays of the mutant OBPs (with the C-terminus eliminated) showed that the C-terminus was important for the ligand binding, but this importance varied with different ligands and OBPs, suggesting that their binding properties depend on the specific interactions between OBP and ligand.
A model-driven ontology approach for manufacturing system interoperability and knowledge sharing

The requirements for the interoperability of semantics and knowledge have become increasingly important in Product Lifecycle Management (PLM), in the drive towards knowledge-driven decision support in the manufacturing industry. This article presents a novel concept, based on the Model Driven Architecture (MDA). The concept has been implemented under the Interoperable Manufacturing Knowledge Systems (IMKS) project in order to understand the extent to which manufacturing system interoperability can be supported using radically new methods of knowledge sharing. The concept exploits the capabilities of semantically well-defined core concepts formalised in a Common Logic-based ontology language. The core semantics can be specialised to configure multiple application-specific knowledge bases, as well as product and manufacturing information platforms. Furthermore, the utilisation of the expressive ontology language and the generic nature of core concepts help support the specification of system mechanisms to enable the verification of knowledge across multiple platforms. An experimental demonstration, using a test case based on the design and manufacture of an aerospace part, has been realised. This has led to the identification of several benefits of the approach, its current limitations as well as the areas to be considered for further work. Crown Copyright 2013 Published by Elsevier B.V. All rights reserved.
MHD Mixed Convective Boundary Layer Flow of a Nanofluid through a Porous Medium due to an Exponentially Stretching Sheet

Magnetohydrodynamic MHD boundary layer flow of a nanofluid over an exponentially stretching sheet was studied. The governing boundary layer equations are reduced into ordinary differential equations by a similarity transformation. The transformed equations are solved numerically using the Nactsheim-Swigert shooting technique together with Runge-Kutta sixorder iteration schemes. The effects of the governing parameters on the flow field and heat transfer characteristics were obtained and discussed. The numerical solutions for the wall skin friction coefficient, the heat and mass transfer coefficient, and the velocity, temperature, and concentration profiles are computed, analyzed, and discussed graphically. Comparison with previously published work is performed and excellent agreement is observed.
Coarse and fine grain programmable overlay architectures for FPGAs

Overlay architectures are programmable logic systems that are compiled on top of a traditional FPGA. These architectures give designers flexibility, and have a number of benefits, such as being designed or optimized for specific application domains, making it easier or more efficient to implement solutions, being independent of platform, allowing the ability to do partial reconfiguration regardless of the underlying architecture, and allowing compilation without using vendor tools, in some cases with fully open source tool chains. This thesis describes the implementation of two FPGA overlay architectures, ZUMA and CARBON. These overlay implementations include optimizations to reduce area and increase speed which may be applicable to many other FPGAs and also ASIC systems. ZUMA is a fine-grain overlay which resembles a modern commercial FPGA, and is compatible with the VTR open source compilation tools. The implementation includes a number of novel features tailored to efficient FPGA implementation, including the utilization of reprogrammable LUTRAMs, a novel two-stage local routing crossbar, and an area efficient configuration controller. CARBON
Pollen-pistil interactions and self-incompatibility in the Asteraceae: new insights from studies of Senecio squalidus (Oxford ragwort).

BACKGROUND
Pollen-pistil interactions are an essential prelude to fertilization in angiosperms and determine compatibility/incompatibility. Pollen-pistil interactions have been studied at a molecular and cellular level in relatively few families. Self-incompatibility (SI) is the best understood pollen-pistil interaction at a molecular level where three different molecular mechanisms have been identified in just five families. Here we review studies of pollen-pistil interactions and SI in the Asteraceae, an important family that has been relatively understudied in these areas of reproductive biology.


SCOPE
We begin by describing the historical literature which first identified sporophytic SI (SSI) in species of Asteraceae, the SI system later identified and characterized at a molecular level in the Brassicaceae. Early structural and cytological studies in these two families suggested that pollen-pistil interactions and SSI were similar, if not the same. Recent cellular and molecular studies in Senecio squalidus (Oxford ragwort) have challenged this belief by revealing that despite sharing the same genetic system of SSI, the Brassicaceae and Asteraceae molecular mechanisms are different. Key cellular differences have also been highlighted in pollen-stigma interactions, which may arise as a consequence of the Asteraceae possessing a 'semi-dry' stigma, rather than the 'dry' stigma typical of the Brassicaceae. The review concludes with a summary of recent transcriptomic analyses aimed at identifying proteins regulating pollen-pistil interactions and SI in S. squalidus, and by implication the Asteraceae. The Senecio pistil transcriptome contains many novel pistil-specific genes, but also pistil-specific genes previously shown to play a role in pollen-pistil interactions in other species.


CONCLUSIONS
Studies in S. squalidus have shown that stigma structure and the molecular mechanism of SSI in the Asteraceae and Brassicaceae are different. The availability of a pool of pistil-specific genes for S. squalidus offers an opportunity to elucidate the molecular mechanisms of pollen-pistil interactions and SI in the Asteraceae.
NAD(P)H oxidase and multidrug resistance protein genetic polymorphisms are associated with doxorubicin-induced cardiotoxicity.

BACKGROUND
A significant number of patients treated with anthracyclines develop cardiotoxicity (anthracycline-induced cardiotoxicity [ACT]), mainly presenting as arrhythmias (acute ACT) or congestive heart failure (chronic ACT). There are no data on pharmacogenomic predictors of ACT.


METHODS AND RESULTS
We genotyped participants of the German non-Hodgkin lymphoma study (NHL-B) who were followed up for the development of heart failure for a median of >3 years. Single-nucleotide polymorphisms (SNPs) were selected from 82 genes with conceivable relevance to ACT. Of 1697 patients, 55 developed acute and 54 developed chronic ACT (cumulative incidence of either form, 3.2%). We detected 5 significant associations with polymorphisms of the NAD(P)H oxidase and doxorubicin efflux transporters. Chronic ACT was associated with a variant of the NAD(P)H oxidase subunit NCF4 (rs1883112, -212A-->G; symbols with right-pointing arrows, as edited?' odds ratio [OR], 2.5; 95% CI, 1.3 to 5.0). Acute ACT was associated with the His72Tyr polymorphism in the p22phox subunit (rs4673; OR, 2.0; 95% CI, 1.0 to 3.9) and with the variant 7508T-->A (rs13058338; OR, 2.6; 95% CI, 1.3 to 5.1) of the RAC2 subunit of the same enzyme. In agreement with these results, mice deficient in NAD(P)H oxidase activity, unlike wild-type mice, were resistant to chronic doxorubicin treatment. In addition, acute ACT was associated with the Gly671Val variant of the doxorubicin efflux transporter multidrug resistance protein 1 (MRP1) (OR, 3.6; 95% CI, 1.6 to 8.4) and with the Val1188Glu-Cys1515Tyr (rs8187694-rs8187710) haplotype of the functionally similar MRP2 (OR, 2.3; 95% CI, 1.0 to 5.4). Polymorphisms in adrenergic receptors previously demonstrated to be predictive of heart failure were not associated with ACT.


CONCLUSIONS
Genetic variants in doxorubicin transport and free radical metabolism may modulate the individual risk to develop ACT.
CERES: Distantly Supervised Relation Extraction from the Semi-Structured Web

The web contains countless semi-structured websites, which can be a rich source of information for populating knowledge bases. Existing methods for extracting relations from the DOM trees of semi-structured webpages can achieve high precision and recall only when manual annotations for each website are available. Although there have been efforts to learn extractors from automatically generated labels, these methods are not sufficiently robust to succeed in settings with complex schemas and information-rich websites. In this paper we present a new method for automatic extraction from semi-structured websites based on distant supervision. We automatically generate training labels by aligning an existing knowledge base with a website and leveraging the unique structural characteristics of semi-structured websites. We then train a classifier based on the potentially noisy and incomplete labels to predict new relation instances. Our method can compete with annotationbased techniques in the literature in terms of extraction quality. A large-scale experiment on over 400,000 pages from dozens of multi-lingual long-tail websites harvested 1.25 million facts at a precision of 90%. PVLDB Reference Format: Colin Lockard, Xin Luna Dong, Arash Einolghozati, Prashant Shiralkar. CERES: Distantly Supervised Relation Extraction from the Semi-Structured Web. PVLDB, 11(10): 1084-1096, 2018. DOI: https://doi.org/10.14778/3231751.3231758
Comparison of an aprepitant regimen with a multiple-day ondansetron regimen, both with dexamethasone, for antiemetic efficacy in high-dose cisplatin treatment.

BACKGROUND
We compared an aprepitant regimen with a control regimen of ondansetron + dexamethasone given for 4 days.


PATIENTS AND METHODS
Patients scheduled to receive cisplatin > or =70 mg/m(2) were randomized to either the aprepitant regimen (aprepitant, ondansetron and dexamethasone on day 1; aprepitant and dexamethasone on days 2-3; dexamethasone on day 4) or control regimen (ondansetron + dexamethasone on days 1-4). Patients recorded vomiting, nausea and rescue therapy use. The primary end point was complete response (no vomiting and no use of rescue therapy) in the overall phase (days 1-5 post-cisplatin).


RESULTS
Complete response rates were higher in the aprepitant than control group in the overall (72% versus 61%; P = 0.003), acute (day 1; 88% versus 79%; P = 0.005) and delayed phases (days 2-5; 74% versus 63%; P = 0.004), as were rates of no vomiting (overall 77% versus 62%, P < or = 0.001; acute 89% versus 81%, P = 0.004; delayed 79% versus 64%, P < or = 0.001). Rates of no rescue therapy were similar between groups.


CONCLUSIONS
Compared with an antiemetic regimen in which ondansetron + dexamethasone were given for 4 days, the aprepitant regimen was superior in the acute, delayed and overall phases of chemotherapy-induced nausea and vomiting. The aprepitant regimen should be considered a new standard of antiemetic therapy for cisplatin-treated patients. www.ClinicalTrials.gov Identifier: NTC00090207.
A survey of local anaesthetic use among general dental practitioners in the UK attending postgraduate courses on pain control

Objective The aim of this study was to identify which local anaesthetic solutions were used by general dental practitioners in the United Kingdom and to determine selection criteria. In addition, differences in anaesthetic choice between recent graduates (≤5 years) and more experienced practitioners were investigated.Material and methods Five hundred and six general dental practitioners attending postgraduate courses on pain control in dentistry completed a questionnaire. Participants were asked to indicate year and place of qualification, anaesthetic solutions available in their surgeries and criteria used in the choice of anaesthetic. In addition, the respondents were asked to indicate choice of local anaesthetic in a number of common medical conditions. Questionnaires were distributed and collected immediately prior to the start of the course presentation and participants were not asked to indicate whether the selection decisions were teaching, experience or evidence based. Data were analysed by using the Chi-square test.Results Lidocaine with epinephrine was the most widely available solution among this group of practitioners (94%), the second most common solution was prilocaine with felypressin (74%). The majority of practitioners had two or more solutions available. Practitioners who qualified within the last five years (14%) were more likely to have articaine available, the most recently introduced local anaesthetic into the UK (p = 0.04, one degree of freedom). Common medical conditions lead to a modification in anaesthetic selection: the use of prilocaine/felypressin increases in the majority of circumstances, although it is avoided in pregnant females by recent graduates.Conclusions Lidocaine/epinephrine continues to be the most common anaesthetic solution used by this group of UK general practitioners. The primary criterion for selection of an anaesthetic agent was perceived efficacy. Prilocaine/felypressin is commonly selected as an alternative solution in the presence of common medical conditions.
The Economic Consequences of Oil Shocks: Differences across Countries and Time

We examine the economic consequences of oil shocks across a set of industrialised economies over time. First, we show that knowing the underlying reason for a change in oil prices is crucial to determine the economic repercussions and the appropriate monetary policy reaction. For oil demand shocks driven by global economic activity, all economies experience a temporary increase in real GDP following an oil price increase, while for oil-specific demand shocks all economies experience a temporary decline in real GDP. The effects of exogenous oil supply shocks are, however, very different across countries when oil prices increase. Whereas net oiland energyimporting economies all face a permanent fall in economic activity following an adverse supply shock, the impact is insignificant or even positive for net energy exporters. Second, the pass-through to inflation turns out to differ considerably across oil-importing economies and strongly depends on the existence of second-round effects via increasing wages. Third, we investigate how the dynamic effects have changed over time. We document a much less elastic oil demand curve since the mid 1980s, which seriously distorts intertemporal comparisons. However, we demonstrate that economies which improved their net energy position the most over time became relatively less vulnerable to oil shocks compared to other economies.
Effects of antiplatelet components of tomato extract on platelet function in vitro and ex vivo: a time-course cannulation study in healthy humans.

BACKGROUND
Natural antithrombotic agents that influence platelet function are of potential interest for primary prevention of cardiovascular disease. Previous reports showed that tomato extracts inhibit platelet aggregation in vitro, but little is known of the active components, their mode of action, or their efficacy in vivo.


OBJECTIVE
The objectives of the study were to examine the antiplatelet activity of specific tomato components by in vitro experimentation and to establish their ex vivo efficacy in healthy humans.


DESIGN
The mechanisms of action of antiplatelet components isolated from tomato extracts were examined in vitro. A 7-h time-course study was carried out in cannulated human subjects (n = 23) to determine the ex vivo efficacy of a supplement drink containing tomato extract and the onset and duration of antiplatelet effects.


RESULTS
The inhibition of ADP-, collagen-, thrombin-, and arachidonate-mediated platelet aggregation by tomato extract components appears to be linked to the inhibition of glycoprotein IIb/IIIa and platelet secretory mechanisms. We found a significant inhibition of baseline platelet function, from 2.9 +/- 1.4% (optimal ADP concentrations; P = 0.03) to 20.0 +/- 4.9% (suboptimal ADP concentrations; P < 0.001), 3 h after supplementation with a dose of tomato extract equivalent to 6 tomatoes. The observed effects persisted for >12 h. Coagulation variables were not affected.


CONCLUSIONS
The ingestion of tomato components with in vitro antiplatelet activity significantly affects ex vivo platelet function. The reported cardioprotective effects of tomatoes are potentially linked to a modulation of platelet function.