LLukas22/scidocs huggingface dataset:
Grid-Interface Bidirectional Converter for Residential DC Distribution Systems—Part 2: AC and DC Interface Design With Passive Components Minimization

With the emerging installations of multitype renewable energy sources and energy storage elements, the dc electronic distribution systems in residential houses/buildings (dc nanogrid) are becoming an alternative future system solution, achieving a zero net-energy consumption and optimized power management. One of the critical components in such a dc system is the grid-interface bidirectional ac–dc power converter, namely the energy control center. Besides, the basic power conversion function, the system interface solution in grid-interface converter is important to successfully interconnect the ac and dc systems as well as fulfill the power quality and EMI regulation codes on both dc and ac sides. This paper presents a complete discussion of several aspects of system interface design for the grid-interface converter under both single-phase and three-phase system conditions. A passive plus active filter solution is proposed to accomplish the common-mode-related noises minimization as well as a dramatic reduction of the converter system volume.
Large scale structure of the Universe: Introduction

The changes of main paradigms on the structure and evolution of the Universe are reviewed. Two puzzles of the modern cosmology, the mean density of matter and the regularity of the Universe on large scales, as well as the possibility to solve these puzzles by the introduction of more complicated form of inflation, are discussed.
Nonmetastatic Ewing family tumors: high-dose chemotherapy with stem cell rescue in poor responder patients. Results of the Italian Sarcoma Group/Scandinavian Sarcoma Group III protocol.

BACKGROUND
High-dose chemotherapy (HDT) was added to conventional chemotherapy in Ewing sarcoma family tumor (EFT) patients, poor responders (PRs) to induction chemotherapy in order to improve their survival.


PATIENTS AND METHODS
Patients aged ≤40 years with nonmetastatic Ewing sarcoma (ES) received vincristine (V), doxorubicin (A), cyclofosfamide (C), actinomycin (Ac), ifosfamide (I) and etoposide (E) (VACAc-IE regimen) as induction chemotherapy. As maintenance treatment, good responders (GR) received nine cycles of VACAc-IE regimen. PRs received three cycles of VAC-IE, mobilizing cycle with CE and HDT with Busulfan and Melphalan with stem cell support.


RESULTS
Three hundred patients [median age 15 years (3-40 years)] entered the study. One patient refused local treatment, 242 (81%) underwent surgery [with radiotherapy (RT) in 80] and 57 (19%) RT alone. No toxic deaths were recorded. Overall GR were 146 (49%). Twenty-eight PR did not receive HDT. At a median follow-up of 64 months (21-116 months), 5-year overall and event-free survival (EFS) were 75% and 69%, respectively. Five-year EFS was 75% for GR, 72% for PR treated with HDT and 33% for PR who did not receive HDT.


CONCLUSIONS
High-dose therapy added to the VACA-IE regimen in PR patients is feasible and effective. Selected groups of patients with ES can benefit from HDT.
DensePose: Dense Human Pose Estimation in the Wild

In this work we establish dense correspondences between an RGB image and a surface-based representation of the human body, a task we refer to as dense human pose estimation. We gather dense correspondences for 50K persons appearing in the COCO dataset by introducing an efficient annotation pipeline. We then use our dataset to train CNN-based systems that deliver dense correspondence 'in the wild', namely in the presence of background, occlusions and scale variations. We improve our training set's effectiveness by training an inpainting network that can fill in missing ground truth values and report improvements with respect to the best results that would be achievable in the past. We experiment with fully-convolutional networks and region-based models and observe a superiority of the latter. We further improve accuracy through cascading, obtaining a system that delivers highly-accurate results at multiple frames per second on a single gpu. Supplementary materials, data, code, and videos are provided on the project page http://densepose.org.
Standards of resuscitation during inter-hospital transportation: the effects of structured team briefing or guideline review - A randomised, controlled simulation study of two micro-interventions

BACKGROUND
Junior physicians are sometimes sent in ambulances with critically ill patients who require urgent transfer to another hospital. Unfamiliar surroundings and personnel, time pressure, and lack of experience may imply a risk of insufficient treatment during transportation as this can cause the physician to loose the expected overview of the situation. While health care professionals are expected to follow complex algorithms when resuscitating, stress can compromise both solo-performance and teamwork.


AIM
To examine whether inter-hospital resuscitation improved with a structured team briefing between physician and ambulance crew in preparation for transfer vs. review of resuscitation guidelines. The effect parameters were physician team leadership (requesting help, delegating tasks), time to resuscitation key elements (chest compressions, defibrillation, ventilations, medication, or a combination of these termed "the first meaningful action"), and hands-off ratio.


METHODS



PARTICIPANTS
46 physicians graduated within 5 years.


DESIGN
A simulation intervention study with a control group and two interventions (structured team briefing or review of guidelines). Scenario: Cardiac arrest during simulated inter-hospital transfer.


RESULTS
Forty-six candidates participated: 16 (control), 13 (review), and 17 (team briefing). Reviewing guidelines delayed requesting help to 162 seconds, compared to 21 seconds in control and team briefing groups (p = 0.021). Help was not requested in 15% of cases; never requesting help was associated with an increased hands-off ratio, from 39% if the driver's assistance was requested to 54% if not (p < 0.01). No statistically significant differences were found between groups regarding time to first chest compression, defibrillation, ventilation, drug administration, or the combined "time to first meaningful action".


CONCLUSION
Neither review nor team briefing improved the time to resuscitation key elements. Review led to an eight-fold increase in the delay to requesting help. The association between never requesting help and an increased hands-off ratio underpins the importance of prioritising available resources. Other medical and non-medical domains have benefited from the use of guidelines reviews and structured team briefings. Reviewing guidelines may compromise the ability to focus on aspects such as team leading and delegating tasks and warrants the need for further studies focusing on how to avoid this cognitive impairment.
Magnetic resonance imaging of Jaccoud's arthropathy in systemic lupus erythematosus.

OBJECTIVE
To perform a detailed magnetic resonance imaging (MRI) analysis of the hands of patients with Jaccoud's arthropathy (JA) secondary to systemic lupus erythematosus (SLE).


METHODS
The hand with more expressive deformities compatible with JA from a group of SLE patients was examined by 1.5-T MRI. The protocol included coronal, sagittal, and axial turbo-spin-echo images before and after the administration of contrast medium. The presence of synovitis, edema, erosion, cysts, and tenosynovitis in the carpometacarpal, metacarpophalangeal, and proximal interphalangeal joints were scored based on a modified Outcome Measures in Rheumatology recommendations.


RESULTS
Twenty SLE patients, (19 women and one man) with median age of 44.7 years (range: 20-76 years), median disease duration of 14.7 years (range: 5-26 years), and median arthritis duration of 13.7 years (range: 4-26 years) were studied. Of the 300 joints evaluated, 202 (67.3%) had some degree of synovitis. Sixteen out of 300 examined joints (5.3%) small areas of erosion were seen in 10 out of the 20 patients (50%). Subchondral bone edema was found in eight out of the 20 (40%) patients or a total of 18 joints (6%). A total of 200 compartments tendons were evaluated, and changes were found in 77 (38.5%) of them. In four out of the 20 patients, the MRI revealed bone cysts.


CONCLUSIONS
The MRI seems to be a non-invasive diagnostic tool in patients with JA secondary to SLE, and may contribute to understanding the mechanism involved in the development of this deformity.
Psychobiological heterogeneity of familial and sporadic schizophrenia

BACKGROUND
Although schizophrenia is presumed to be heterogeneous, there has been limited success distinguishing familial from sporadic cases. We used psychobiological measures to examine heterogeneity, as they may be closer to neurobiology than symptoms. Smooth pursuit eye movement quality (SPEM) and dichotic listening (DL) tests to tones and words were used to assess hemispheric laterality asymmetry.


METHODS
Forty-six research unit patients participated in assessments of family history (FH) and physiological measures. FH was categorized by three exclusive groups: FH-1 patients had a chronic schizophrenia-related psychosis in a first-degree relative, FH-2 had it in second-degree relative, and FH-3 had no family member with a reoccurrence.


RESULTS
Analysis of variance showed a significant group difference for SPEM and DL tones. SPEM was significantly worse in all three schizophrenia groups than for the normal comparison subjects. Among the schizophrenia groups, the nonfamilial group (FH-3) had the worst SPEM quality, FH-2 had intermediate quality, and FH-1 had the best quality. Conversely, only the nonfamilials (FH-3) had normal right hemispheric lateralization for tones, whereas familials did not, and FH-2 again had intermediate values. The lateralization quotient for DL words did not significantly differ among the groups.


CONCLUSIONS
SPEM was affected most in sporadic, not familial schizophrenia, whereas dichotic listening was most affected in familial schizophrenia. This double dissociation supports the utility of the familial/sporadic distinction and suggests that etiological factors in different forms of schizophrenia may impact principally on distinct neurobiological substrates, despite similar patient phenomenology.
Don't let radiation scare trump patient care: 10 ways you can harm your patients by fear of radiation-induced cancer from diagnostic imaging.

To cite: Brody AS, Guillerman RP. Thorax Published Online First: [please include Day Month Year] doi:10.1136/thoraxjnl2014-205499 RADIATION For many people, the term radiation is linked to atomic bombs, cancer and death. Even without these associations, ionising radiation in the form of X-rays is frightening. Acute exposure to X-rays cannot be sensed in any way, yet can be lethal within days or weeks if received at a high enough dose. There is clearly good reason to be concerned about unnecessary exposure to X-rays. In diagnostic imaging, balancing this danger is the benefit that can be realised from the use of these X-rays. When a group of leading general internists was asked to rank 30 medical innovations by the most adverse effect on their patients if the innovation were unavailable, the most important innovation ‘by a considerable margin’ was MRI and CT scanning. MRI does not use ionising radiation, but CT scanning is more widely available, can be completed in under 10 s compared with 20–30 min for MRI, and is the imaging modality of choice for acute trauma to the head or abdomen and for evaluation of the lungs. How can your concern about radiation risk hurt your patient? Simply put, by not doing an imaging study that could benefit the patient more, or by unduly compromising image quality in an effort to reduce radiation dose. The following are 10 common ways that a medical caregiver can wrongly assess the risk : benefit of imaging to the detriment of his or her patients.
Can analyses of electronic patient records be independently and externally validated? Study 2—the effect of β-adrenoceptor blocker therapy on cancer survival: a retrospective cohort study

OBJECTIVES
To conduct a fully independent, external validation of a research study based on one electronic health record database using a different database sampling from the same population.


DESIGN
Retrospective cohort analysis of β-blocker therapy and all-cause mortality in patients with cancer.


SETTING
Two UK national primary care databases (PCDs): the Clinical Practice Research Datalink (CPRD) and Doctors' Independent Network (DIN).


PARTICIPANTS
CPRD data for 11,302 patients with cancer compared with published results from DIN for 3462 patients; study period January 1997 to December 2006.


PRIMARY AND SECONDARY OUTCOME MEASURES
All-cause mortality: overall; by treatment subgroup (β-blockers only, β-blockers plus other blood pressure lowering medicines (BPLM), other BPLMs only); and by cancer site.


RESULTS
Using CPRD, β-blocker use was not associated with mortality (HR=1.03, 95% CI 0.93 to 1.14, vs patients prescribed other BPLMs only), but DIN β-blocker users had significantly higher mortality (HR=1.18, 95% CI 1.04 to 1.33). However, these HRs were not statistically different (p=0.063), but did differ for patients on β-blockers alone (CPRD=0.94, 95% CI 0.82 to 1.07; DIN=1.37, 95% CI 1.16 to 1.61; p<0.001). Results for individual cancer sites differed by study, but only significantly for prostate and pancreas cancers. Results were robust under sensitivity analyses, but we could not be certain that mortality was identically defined in both databases.


CONCLUSIONS
We found a complex pattern of similarities and differences between databases. Overall treatment effect estimates were not statistically different, adding to a growing body of evidence that different UK PCDs produce comparable effect estimates. However, individually the two studies lead to different conclusions regarding the safety of β-blockers and some subgroup effects differed significantly. Single studies using even internally well-validated databases do not guarantee generalisable results, especially for subgroups, and confirmatory studies using at least one other independent data source are strongly recommended.
Conformational Studies on 1,3-Dioxepanes. Part V. The Effect of Introduction of an sp2-hybridized Carbon Atom

It has been demonstrated, by a consideration of geminal and long-range coupling constants, that the introduction of an sp2-hybridized carbon atom into a 1,3-dioxepane ring markedly affects the conformational equilibrium.
Comparative randomised trial of online cognitive-behavioural therapy and an information website for depression: 12-month outcomes.

BACKGROUND
An earlier paper reported positive outcomes immediately following access to a cognitive-behavioural therapy (CBT) internet intervention and a depression information website.


AIMS
To determine 6-month and 12-month outcomes of the interventions relative to a placebo control condition.


METHOD
Participants allocated to the depression information website condition, the CBT internet intervention and the placebo control condition were followed up at 6 and 12 months by survey. The primary outcome measure was the Center for Epidemiologic Studies-Depression (CES-D) scale. Of 525 participants recruited, 79% completed their assigned intervention and 60% were retained at 12-month follow-up. Attrition was handled using mixed-model repeated-measures ANOVA.


RESULTS
Both the CBT site and depression information sites were associated with statistically significant benefits in CES-D score reduction compared with controls at post-test. At 6-months follow-up, the reduction seen for the people allocated to the CBT arm remained significant, whereas that for the depression information website arm was not. At 12 months, both active interventions were statistically significantly superior to the control condition.


CONCLUSIONS
There is some evidence that benefits of these brief internet interventions are retained beyond their endpoint. The impact of human support provided by interviewers in the trial must be considered when comparing these outcomes to routine use of both internet interventions.
PCB Defect Detection Using Image Processing And Embedded System

This project is motivated mainly by the need for more efficient techniques in inspection of the PCB in fabrication process. The objectives of this project are to provide an inexpensive and comprehensive defect detection technique. Introducing and implementing a PCB inspection system using image processing to remove the subjective aspects of manual inspection. At the same time, this system provides real time assessment of the PCB. The basic technique of the proposed system is to detect the defect based on the digital image of the PCB using image processing techniques. There are a few steps to detect defect of bare PCB. First of all, the system should collect PCB images through camera. After special image recognition and analysis process, the images should be compared with the templates, thus the common defects such as short circuit, open circuit, shorts, missing holes and other defects can be found out precisely. To get the details about the defects, extracting the structural features based on the regional properties such as perimeter, regional areas, orientation etc. Finally the recognition results will be acquired and reported. Under the control of the Controller, the PCB delivering components like conveyor belt, DC motor automatically move the given PCBs. Image acquisition and moving control subsystem receives the central computer’s control commands, acquires the PCB images real-timely and processes them using MATLAB. The result data will be sent to the central computer and displayed on GUI
Mycophenolate mofetil versus azathioprine in patients with chronic active ulcerative colitis: a 12-month pilot study

OBJECTIVE:Ulcerative colitis (UC) is an inflammatory bowel disease (IBD) of unknown etiology frequently requiring long-term therapy for control of symptoms and prevention of relapse. Azathioprine (AZA) has been shown to be effective and safe in the treatment of chronic active UC. However, the alternatives to treatment with AZA are limited. Our aim was to compare the efficacy and safety of treatment with mycophenolate mofetil (MMF)/prednisolone versus standard immunosuppressive treatment with azathioprine (AZA)/prednisolone in patients with chronic active UC.METHODS:The study was designed as an open comparison of MMF versus AZA. Twenty-four patients with active UC (Rachmilewitz score ≥6 points) were randomly assigned to the MMF (20 mg/kg)/prednisolone or AZA (2 mg/kg)/prednisolone group. The initial prednisolone dosage was 50 mg and was tapered according to a standard protocol. Treatment was scheduled for 1 yr.RESULTS:The rates of remission were higher in the AZA/prednisolone group (n = 12) than in the MMF/prednisolone group (n = 12) throughout the study. Remission rates were 92% versus 67% after 4 wk, 92% versus 67% after 3 months, 92% versus 67% after 6 months, 83% versus 78% after 9 months, and 100% versus 88% after 1 yr. The number of patients not requiring steroids was higher in the AZA/prednisolone group than in the MMF/prednisolone group. Moreover, in the AZA/prednisolone group no severe adverse events were recorded, whereas in the MMF/prednisolone group two severe adverse events were observed: one patient discontinued MMF after 6 months because of recurrent upper airway infections, and one patient exhibited a bacterial meningitis after 9 months.CONCLUSIONS:Treatment with AZA/prednisolone appears to be more effective and safe compared to MMF/prednisolone in patients with chronic active UC. MMF might be an alternative treatment for patients with contraindications to AZA. To further evaluate the effects of MMF in active UC, a placebo-controlled double-blinded study appears warranted.
Adolescent use of school-based health centers and high school dropout.

OBJECTIVE
To determine the association between use of school-based health centers (SBHCs) and school dropout.


DESIGN
Quasi-experimental longitudinal analysis of a retrospective student cohort, with SBHC use as the independent variable. We statistically controlled for dropout risk and used propensity score regression adjustment to control for several factors associated with SBHC use.


SETTING
Integrated database from an urban public school district (academic outcomes) and department of public health (SBHC use).


PARTICIPANTS
District-enrolled students in their first semester of ninth grade in 2005 (N = 3334), followed up through their anticipated on-time graduation semester of 12th grade in 2009. Students were divided into 4 groups: never used (47%); low use (23%); moderate use (20%); and high users (10%).


OUTCOME MEASURE
Time to nongraduation (described as dropout).


RESULTS
Low to moderate SBHC use (0.125-2.5 visits per semester) was associated with a 33% reduction in dropout compared with non-SBHC users. The high-use group (>2.5 visits per semester) did not have dropout rates that differed from nonusers. For SBHC users who did drop out, dropout occurred approximately 1 semester later than nonusers. Exploratory analyses revealed that the association between SBHC use and prevention of dropout was greatest for higher-risk students.


CONCLUSIONS
This study found an association between low to moderate SBHC use and reductions in dropout for high school students in an urban school district, especially for students at higher risk for dropout. This study supports the theory that benefits of SBHCs extend beyond managing physical and mental health needs to include academic outcomes.
Prognostic implications of the standardized study of resection margins in pancreatic cancers.

INTRODUCTION
Involvement of surgical resection margins is a fundamental prognostic factor in pancreatic oncological surgery. However, there is a lack of standardized histopathology definition. The aims of this study are to investigate the real rate of R1 resections when surgical specimens are evaluated according to a standardized protocol and to study its survival implications.


PATIENTS Y METHODS
One hundred consecutive surgically resected patients with pancreatic ductal adenocarcinoma were included in the study. They were further divided in 2 groups: pre-protocol, evaluated before the introduction of the standardized protocol and post-protocol, analyzed with the standardized protocol.


RESULTS
R0 resection rate in the pre-protocol group was 78%, falling to 47% after the introduction of the standardized protocol (p=0,003). The posterior retroperitoneal margin was the most frequently involved margin. In cases with tumors located at the pancreatic head and analyzed according to the standardized protocol R1 involvement negatively affected survival. Median survival in the R0 group was 22 months versus 16 in those with the margin involved (HR: 2.044; IC 95% 1,00-4,16; P=.043).


CONCLUSIONS
Standardized evaluation of the retroperitoneal margins in pancreatic cancer increases the rate of R1 patients. In cases with pancreatic cancer located at the pancreatic head involvement of posterior retroperitoneal margin significantly decreases survival.