LLukas22/scidocs huggingface dataset:
Secure Biometric-Based Authentication Scheme Using Chebyshev Chaotic Map for Multi-Server Environment

Multi-server environment is the most common scenario for a large number of enterprise class applications. In this environment, user registration at each server is not recommended. Using multi-server authentication architecture, user can manage authentication to various servers using single identity and password. We introduce a new authentication scheme for multi-server environments using Chebyshev chaotic map. In our scheme, we use the Chebyshev chaotic map and biometric verification along with password verification for authorization and access to various application servers. The proposed scheme is light-weight compared to other related schemes. We only use the Chebyshev chaotic map, cryptographic hash function and symmetric key encryption-decryption in the proposed scheme. Our scheme provides strong authentication, and also supports biometrics & password change phase by a legitimate user at any time locally, and dynamic server addition phase. We perform the formal security verification using the broadly-accepted Automated Validation of Internet Security Protocols and Applications (AVISPA) tool to show that the presented scheme is secure. In addition, we use the formal security analysis using the Burrows-Abadi-Needham (BAN) logic along with random oracle models and prove that our scheme is secure against different known attacks. High security and significantly low computation and communication costs make our scheme is very suitable for multi-server environments as compared to other existing related schemes.
Endoscopic techniques in resection of anterior skull base/paranasal sinus malignancies.

OBJECTIVE
The objective of this study was to examine the role of endoscopic approaches to the resection of anterior skull base and paranasal sinus malignancies at one tertiary care medical center.


STUDY DESIGN
The authors conducted a retrospective chart review over a period of 17 years.


METHODS
Patients undergoing anterior skull base resections for malignancies over a 17-year period were reviewed. Data were collected on each patient with respect to the pathology of the tumor and approach used as well as demographic and follow-up information.


RESULTS
A total of 78 patients were treated at a tertiary care medical center for malignancies of the paranasal sinuses and anterior skull base. The most common diagnosis was squamous cell carcinoma occurring in 33% of the cases. The remaining pathologies included esthesioneuroblastoma (23%), adenoid cystic carcinoma (15%), melanoma (3%), sinonasal undifferentiated carcinoma (3%), lymphoma (5%), nasopharyngeal carcinoma (4%), and other tumor types (14%). Endoscopic techniques were used extensively in this population of patients. Combined approaches using a sublabial/transmaxillary approach and coronal approaches were used when indicated and complemented the endoscopic approach. A majority of patients were without evidence of disease at the end of this review. Using endoscopic techniques allowed for acceptable cosmetic results and facial incisions were used minimally.


CONCLUSION
With complete endoscopic surgical resection followed by radiation therapy, local recurrence, morbidity, and cosmetic deformity have been minimized. The microscopic view provided by endoscopic techniques, with or without complementary approaches, allows for complete tumor removal.
Congenital renal anomalies detected in adulthood

OBJECTIVE
To document the types of congenital renal anomalies detected in adulthood, the clinical presentation and complications of these renal anomalies, and the most useful imaging modality in detecting a renal anomaly.


MATERIALS AND METHODS
This study was approved by the institutional review board and informed consent was waived. Between January 2007 and January 2011, the clinical data and imaging studies of 28 patients older than 18 years diagnosed with renal anomaly at the authors' institution were retrospectively reviewed. Renal anomalies in this study included only those with abnormality in position and in form.


RESULTS
Of these 28 patients, 22 underwent imaging studies and their results constituted the material of this study. Of the 22 patients, 14 had horseshoe kidneys (HSK), four had crossed renal ectopia and four had malrotation. Sixteen patients were men and six were women. The patients ranged in age from 19 to 74 years (mean age 51.1 years). Clinical presentations were abdominal pain (13), fever (13), haematuria (4), palpable mass (2), asymptomatic (2), polyuria (1) dysuria (1), blurred vision (1), and headache with weakness of left extremities (1). Imaging studies included abdominal radiograph (15), intravenous pyelography (IVP) (8), retrograde pyelography (RP) (4), ultrasonography (US) (7), and computed tomography (CT) (9). Associated complications included urinary tract stones (17), urinary tract infection (16), hydronephrosis (12), and tumours (2). Abdominal radiograph suggested renal anomalies in nine out of 15 studies. IVP, RP, US and CT suggested anomalies in all patients who had these studies performed. However, CT was the best imaging modality to evaluate anatomy, function and complications of patients with renal anomalies.


CONCLUSION
HSK was the most common renal anomaly, with abdominal pain and fever being the most common presentations. UTI and stones were the most common complications. IVP, RP, US and CT can be used to diagnose renal anomalies but CT is the best imaging modality to evaluate renal anatomy, function and its complications.
Improving sentence compression by learning to predict gaze

We show how eye-tracking corpora can be used to improve sentence compression models, presenting a novel multi-task learning algorithm based on multi-layer LSTMs. We obtain performance competitive with or better than state-of-the-art approaches.
Expression of miRNAs in Papillary Thyroid Carcinomas Is Associated with BRAF Mutation and Clinicopathological Features in Chinese Patients

MicroRNAs (miRNAs) dysregulation has been shown to play a critical regulatory role in papillary thyroid carcinomas (PTCs). BRAF mutation is associated with poor clinicopathological outcomes in PTC. In order to identify a possible association between dysregulated miRNA expression and BRAF mutation as well as clinicopathological features in Chinese patients with PTC, we examined the expression levels of five reported dysregulated miRNAs (miRNA-221, miRNA-222, miRNA-146b, miRNA-181, and miRNA-21) and determined BRAF mutation status in 52 patients with PTC and 52 patients with benign thyroid nodules (BTNs). The expression levels of all five miRNAs were significantly increased in PTC when compared to BTN. The BRAF mutation occurred more frequently in PTC cases with advanced TNM stage. Importantly, miRNA-221, miRNA-222, miRNA-146b, and miRNA-181 expression levels were significantly higher in PTC patients with BRAF mutation. In addition, enhanced expression of miRNA-221 and miRNA-222 was found in patients with cervical lymph node metastasis and advanced TNM stage. Increased expression of miRNA-221 and miR-181 was evidenced in patients with larger tumors. These findings showed a potential role of this distinct profile of miRNAs in differentiating PTC from BTN. BRAF mutation might regulate or interact with miRNA in the pathogenesis and progression of PTC.
Clinical effects of actarit in rheumatoid arthritis: improvement of early disease activity mediated by reduction of serum concentrations of nitric oxide.

OBJECTIVE
We previously reported the presence of high serum concentrations of nitric oxide (NO) in patients with rheumatoid arthritis (RA). In this study we evaluated the effect of actarit on patients with early and advanced stages of RA and the relationship between RA activity and serum NO levels.


METHODS
Thirty-seven RA patients who were undergoing care at Sasebo Chuo Hospital were entered into the study. Patients were divided into two groups based on the severity of their disease: group I (stages I and II) and group II (stages III and IV). NO concentrations in serum samples were measured by the chemiluminescence method.


RESULTS
Morning stiffness, the number of tender and swollen joints, grip strength, pain score, modified Health Assessment Questionnaire score (mHAQ), ESR, CRP and the Lansbury index significantly improved during 24 weeks of treatment in group I. Patients in group II did not show improvement in morning stiffness, pain score, ESR or CRP during treatment. The concentrations of NO in group I were significantly reduced at 8 weeks after administration of actarit. Those in group II showed a delayed response; a significant decrease in NO occurred at 20 weeks. The improvement in the number of tender and swollen joints, grip strength, pain score, mHAQ and Lansbury index noted in group I preceded the fall in NO concentrations.


CONCLUSION
Our results demonstrate that actarit improves disease activity in early phase RA by suppressing serum NO levels. The results suggest that NO is a useful marker for monitoring improvement in the early stages of RA.
Automated Mapping Generation for Converting Databases into Linked Data

Most of the data on the Web is stored in relational databases. In order to make the Semantic Web grow we need to provide easy-to-use tools to convert those databases into linked data, so that even people with little knowledge of the semantic web can use them. Some programs able to convert relational databases into RDF files have been developed, but the user still has to link manually the database attribute names to existing ontology properties and this generated “linked data” is not actually linked with external relevant data. We propose here a method to associate automatically attribute names to existing ontology entities in order to complete the automation of the conversion of databases. We also present a way rather basic, but with low error rate to add links automatically to relevant data from other data sets.
Inferred Designs

To meet the needs of rapid software evolution, the authors introduce models and tools for a new methodology: inferred designs.
17-Italian Foot Function Index with numerical rating scale: development, reliability, and validity of a modified version of the original Foot Function Index.

BACKGROUND
Clinical research quantifies symptoms and signs of pain.


OBJECTIVE
To develop a brief outcome measure to assess foot and ankle conditions, the psychometric properties of a modified version of the original Foot Function Index (FFI) were examined.


METHODS
Eighty-six subjects with musculoskeletal foot and ankle disorders were enrolled. The internal consistency and test-retest reliability were evaluated by using Cronbach's α and intraclass correlation coefficient (ICC). Criterion validity was tested by Pearson's correlation coefficient between 17 items of the Italian FFI (17-IFFI) and the Lower Extremity Functional Scale (LEFS). The responsiveness was calculated using the receiver operating characteristic curve (ROC).


RESULTS
Cronbach's Alpha was 0.95 (95% CI: 0.92, 0.99). The intra-interviewer and inter-interviewer ICC values were, respectively, 0.92 (95% CI: 0.88-10 0.96) and 0.90 (95% CI: 0.89-0.94). Correlations between the 17-IFFI scores and the LEFS scores were -0.564 and -0.456 at the initial and at the end of the treatment, respectively. The ROC analysis revealed an area under the curve of 0.732 (95% CI: 0.61-0.82) for the 17-IFFI and 0.633 (95% CI: 0.52-0.71) for the LEFS score.


CONCLUSIONS
The 17-IFFI is a reliable and valid scale and we recommend its application to evaluate the effectiveness of a treatment in patients with musculoskeletal foot and ankle disorders.
A Novel Approach to Automatic Road-Accident Detection using Machine Vision Techniques

In this paper, a novel approach for automatic road accident detection is proposed. The approach is based on detecting damaged vehicles from footage received from surveillance cameras installed in roads and highways which would indicate the occurrence of a road accident. Detection of damaged cars falls under the category of object detection in the field of machine vision and has not been achieved so far. In this paper, a new supervised learning method comprising of three different stages which are combined into a single framework in a serial manner which successfully detects damaged cars from static images is proposed. The three stages use five support vector machines trained with Histogram of gradients (HOG) and Gray level co-occurrence matrix (GLCM) features. Since damaged car detection has not been attempted, two datasets of damaged cars Damaged Cars Dataset-1 (DCD-1) and Damaged Cars Dataset-2 (DCD-2) – was compiled for public release. Experiments were conducted on DCD-1 and DCD-2 which differ based on the distance at which the image is captured and the quality of the images. The accuracy of the system is 81.83% for DCD-1 captured at approximately 2 meters with good quality and 64.37% for DCD-2 captured at approximately 20 meters with poor quality. Keywords—Feature extraction; Image denoising; Machine vision; object detection; Supervised learning; Support vector machines
Pharmacist intervention in primary care to improve outcomes in patients with left ventricular systolic dysfunction.

BACKGROUND
Meta-analysis of small trials suggests that pharmacist-led collaborative review and revision of medical treatment may improve outcomes in heart failure.


METHODS AND RESULTS
We studied patients with left ventricular systolic dysfunction in a cluster-randomized controlled, event driven, trial in primary care. We allocated 87 practices (1090 patients) to pharmacist intervention and 87 practices (1074 patients) to usual care. The intervention was delivered by non-specialist pharmacists working with family doctors to optimize medical treatment. The primary outcome was a composite of death or hospital admission for worsening heart failure. This trial is registered, number ISRCTN70118765. The median follow-up was 4.7 years. At baseline, 86% of patients in both groups were treated with an angiotensin-converting enzyme inhibitor or an angiotensin receptor blocker. In patients not receiving one or other of these medications, or receiving less than the recommended dose, treatment was started, or the dose increased, in 33.1% of patients in the intervention group and in 18.5% of the usual care group [odds ratio (OR) 2.26, 95% CI 1.64-3.10; P< 0.001]. At baseline, 62% of each group were treated with a β-blocker and the proportions starting or having an increase in the dose were 17.9% in the intervention group and 11.1% in the usual care group (OR 1.76, 95% CI 1.31-2.35; P< 0.001). The primary outcome occurred in 35.8% of patients in the intervention group and 35.4% in the usual care group (hazard ratio 0.97, 95% CI 0.83-1.14; P = 0.72). There was no difference in any secondary outcome.


CONCLUSION
A low-intensity, pharmacist-led collaborative intervention in primary care resulted in modest improvements in prescribing of disease-modifying medications but did not improve clinical outcomes in a population that was relatively well treated at baseline.
Pragmatic Language and School Related Linguistic Abilities in Siblings of Children with Autism

Siblings of probands with autism spectrum disorders are at higher risk for developing the broad autism phenotype (BAP). We compared the linguistic abilities (i.e., pragmatic language, school achievements, and underling reading processes) of 35 school-age siblings of children with autism (SIBS-A) to those of 42 siblings of children with typical development. Results indicated lower pragmatic abilities in a subgroup of SIBS-A identified with BAP related difficulties (SIBS-A-BAP) whereas school achievements and reading processes were intact. Furthermore, among SIBS-A-BAP, significant negative correlations emerged between the severity scores on the Autism Diagnostic Observation Schedule and full and verbal IQ scores. These results are discussed in the context of the developmental trajectories of SIBS-A and in relation to the BAP.
Subacute combined degeneration: clinical, electrophysiological, and magnetic resonance imaging findings.

OBJECTIVE
Vitamin B12 deficiency is a systemic disease that often affects the nervous system. One of the most prevalent manifestations is subacute combined degeneration (SCD) of the spinal cord. To access the clinical, electrophysiological, and structural abnormalities associated with SCD, a study was conducted in nine patients.


METHODS
Clinical, electrophysiological (electroneurography, somatosensory and motor evoked potentials), and MRI evaluations were performed in patients before and after treatment.


RESULTS
The most prominent clinical and electrophysiological findings in all patients were dysfunctions of the posterior column. Corresponding hyperintense lesions in the posterior column of the spinal cord were found in two patients by T2 weighted MRI. Damage to the central motor pathway was identified in four patients. Demyelinating neuropathy was present in one patient and axonal neuropathy in four. All patients showed improvement of their symptoms after treatment with cobalamin. Abnormalities of the spinal cord on MRI disappeared early in recovery. Motor evoked potentials and median somatosensory evoked potentials typically normalised after treatment, whereas tibial somatosensory evoked potentials remained abnormal in most patients.


CONCLUSIONS
Clinical, electrophysiological, and MRI findings associated with SCD in vitamin B12 deficiency are diverse. Thus vitamin B12 deficiency should be considered in the differential diagnosis of all spinal cord, peripheral nerve, and neuropsychiatric disorders.
A Mutual Agreement Signature Scheme for Secure Data Provenance

Derived from the field of art curation, digital provenance is an unforgeable record of a digital object’s chain of successive custody and sequence of operations performed on it. Digital provenance forms an immutable directed acyclic graph (DAG) structure. Recent works in digital provenance have focused on provenance generation, storage and management frameworks in different fields. In this paper, we address two important aspects of digital provenance that have not been investigated thoroughly in existing works: 1) capturing the DAG structure of provenance and 2) supporting dynamic information sharing. We propose a scheme that uses signature-based mutual agreements between successive users to clearly delineate the transition of responsibility of the document as it is passed along the chain of users. In addition to preserving the properties of confidentiality, immutability and availability for a digital provenance chain, it supports the representation of DAG structures of provenance. Our scheme supports dynamic information sharing scenarios where the sequence of users who have custody of the document is not predetermined. Security analysis and empirical results indicate that our scheme improves the security of the existing Onion and PKLC provenance schemes with comparable performance. Keywords—Provenance, cryptography, signatures, integrity, confidentiality, availability
The form factors of ωπ0 and π+π− at ψ(2S)

Abstract The measurements of ψ (2 S )→ ωπ 0 and ψ (2 S )→ π + π − in e + e − experiments are examined. It is found that the non-resonance virtual photon annihilation gives large contributions to the observed cross sections of these two processes. By including this contribution, the form factors and branching fractions of these two decay modes are revised.
Carboplatin/gemcitabine alternating with carboplatin/pegylated liposomal doxorubicin and carboplatin/cyclophosphamide in platinum-refractory/resistant paclitaxel - pretreated ovarian carcinoma.

OBJECTIVE
In this phase II study the efficacy and toxicity of an alternating chemotherapy regimen was examined in platinum-resistant relapsed epithelial ovarian cancer (EOC) patients.


METHODS
Forty-five patients with platinum-refractory/resistant relapsed EOC, previously treated with carboplatin+paclitaxel+/-epirubicin were included. The regimen was consisted of gemcitabine 800 mg/m(2) (days 1+8) and carboplatin AUC 5, alternating with pegylated liposomal doxorubicin 30 mg/m(2) and carboplatin AUC 5, alternating with carboplatin AUC 5 and cyclophosphamide 600 mg/m(2), every 3 weeks for a total of 9 cycles.


RESULTS
Among 38 patients with measurable disease, 39.4% (95% CI: 23.2-55.7) responded (five complete response and 10 partial response), while 30 out of 40 (75%) patients assessable by CA125 criteria had a serological response. Responses were more frequent in patients with platinum-free interval (PFI) 3-6 months than in those with PFI 0-3 months, but this was not statistically-significant. After a median follow-up of 19.5 months (range, 1.0-37+ months) the median progression-free survival was 7.1 months (95% CI: 3.4-10.8) and the median survival (OS) was 18.8 months (95% CI: 15.6-22.0). For patients with PFI 0-3 months PFS was 4.3 (95% CI: 0.8-7.8) months, while for those with PFI 3-6 months PFS was 8.9 (95% CI: 5.3-12.4) months (p=0.062). The regimen was well-tolerated and the main grade 3-4 toxicity was myelosuppression, palmar-plantar erythrodysesthesia, allergy and fatigue.


CONCLUSION
This alternating regimen, including carboplatin, gemcitabine, liposomal doxorubicin and cyclophosphamide, is an active and well-tolerated treatment in platinum relapsed/refractory EOC patients.
Big Graph Analytics: The State of the Art and Future Research Agenda

Analytics over big graphs is becoming a first-class challenge in database research, with fast-growing interest from both the academia and the industrial community. This problem arises in several application scenarios, ranging from social networks to large-scale network systems, from knowledge discovery to cybersecurity, and so forth. Following this major trend, this paper explores actual state-of-the-art results in the area of analytics over big graphs and discusses open research issues and actual trends in such area.