LLukas22/scidocs huggingface dataset:
Designing a theory- and evidence-based tailored eHealth rehabilitation aftercare program in Germany and the Netherlands: study protocol

BACKGROUND
Cardiac rehabilitation programs aim to improve health status and to decrease the risk of further cardiac events. Persons undergoing rehabilitation often have difficulties transferring the learned health behaviors into their daily routine after returning home and maybe to work. This includes physical activity as well as fruit and vegetable consumption. Computer-based tailored interventions have been shown to be effective in increasing physical activity as well as fruit and vegetable consumption. The aim of this study is, to support people in transferring these two learned behavior changes and their antecedents into their daily life after cardiac rehabilitation.


METHODS
The study will have a randomized controlled design and will be conducted among German and Dutch people who participated in cardiac rehabilitation. The study will consist of one intervention group which will be compared to a waiting list control group. During the eight week duration of the intervention, participants will be invited to participate in the online after-care program once per week. The intervention encourages participants to define individual health behavior goals as well as action, and coping plans to reach these self-determined goals. The effectiveness of the program will be compared between the intervention condition and the control group in terms of behavior change, antecedents of behavior change (e.g., self-efficacy), ability to return to work and increased well-being. Further, subgroup-differences will be assessed including differences between the two countries, socioeconomic inequalities and across age groups.


DISCUSSION
The present study will make a contribution to understanding how such an online-based tailored interventions enables study participants to adopt and maintain a healthy lifestyle. Implications can include how such an online program could enrich cardiac rehabilitation aftercare further.


TRIAL REGISTRATION
NTR 3706, NCT01909349.
An FPGA Implementation of Incremental Clustering for Radar Pulse Deinterleaving

Background A military aircraft in a hostile environment may need to use radar jamming in order to avoid being detected or engaged by the enemy. Effective jamming can require knowledge of the number and type of enemy radars; however, the radar receiver on the aircraft will observe a single stream of pulses from all radar emitters combined. It is advantageous to separate this collection of pulses into individual streams each corresponding to a particular emitter in the environment; this process is known as pulse deinterleaving. Pulse deinterleaving is critical for effective electronic warfare (EW) signal processing such as electronic attack (EA) and electronic protection (EP) because it not only aids in the identification of enemy radars but also permits the intelligent allocation of processing resources.
Routine Drainage of the Operative Bed Following Elective Distal Pancreatectomy Does Not Reduce the Occurrence of Complications

: Routine drainage of the operative bed following elective pancreatectomy remains controversial. Data specific to distal pancreatectomy (DP) have not been examined in a multi-institutional collaborative. : Data from the American College of Surgeons-National Surgical Quality Improvement Program Pancreatectomy Demonstration Project were utilized. The impact of drain placement on development of pancreatectomy-related and overall morbidity were analyzed. Propensity scores for drain placement were calculated, and nearest neighbor matching was used to create a matched cohort. Groups were compared using bivariate and logistic regression analyses. : Over 14 months, 761 patients undergoing DP were accrued; 606 were drained. Propensity score matching was possible in 116 patients. Drain and no drain groups were not different with respect to multiple preoperative and operative variables. All pancreatic fistulas (p < 0.01) and overall morbidity (p < 0.05) were more common in patients who received a drain. The placement of a drain did not reduce the incidence of clinically relevant pancreatic fistula nor the need for postoperative procedures. : Placement of drains following elective distal pancreatectomy was associated with a higher overall morbidity and pancreatic fistulas. Drains did not reduce intra-abdominal septic morbidity, clinically relevant pancreatic fistulas, nor the need for postoperative therapeutic intervention.
Psychological well-being status among medical and dental students in Makkah, Saudi Arabia: a cross-sectional study.

OBJECTIVES
Medical and dental students experience poor psychological well-being relative to their peers. This study aimed to assess the psychological well-being among medical and dental students in Saudi Arabia, identify the high-risk groups and assess the association between the psychological well-being and the academic performance.


METHODS
In this cross-sectional study, 422 preclinical medical and dental students at Umm Al-Qura University, Saudi Arabia, were recruited to assess their depression, anxiety, stress, self-efficacy and satisfaction with life levels using 21-items Depression Anxiety Stress Scale (DASS-21), General Self-Efficacy (GSE) scale and Satisfaction With Life Scale (SWLS). Students' academic weighted grades were obtained later. Descriptive statistics and univariate general linear model were used to analyse data.


RESULTS
High levels of depression (69.9%), anxiety (66.4%) and stress (70.9%) were indicated, whereas self-efficacy (mean = 27.22, sd = 4.85) and life satisfaction (mean = 23.60, sd = 6.37) were within the normal range. Female medical students had higher psychological distress in contrast to dental students. In general, third-year students were more depressed and stressed in comparison with second-year students, except for stress among dental students. Moreover, all females had higher self-efficacy than males. Life satisfaction was higher within the second-year and high family income students. Depression was the only psychological variable correlated with the academic performance.


CONCLUSION
High levels of psychological distress were found. Female medical students had higher psychological distress than males, whereas male dental students had higher distress than female. Medical students at third year were more depressed and stressed. Dental students were more depressed in the third year, but more stressed in the second year. Attention should be directed towards reducing the alarming levels of depression, anxiety and stress among medical and dental students.
Uniqueness via the adjoint problems for systems of conservation laws

We prove a result of uniqueness of the entropy weak solution to the Cauchy problem for a class of nonlinear hyperbolic systems of conservation laws, that includes in particular the p-system of isentropic gas dynamics. Our result concerns weak solutions satisfying the, as we call it, Wave Entropy Condition or WEC, for short, introduced in this paper. The main feature of this condition is that it concerns both shock waves and rarefaction waves present in a solution. For the proof of uniqueness, we derive an existence result (respectively a uniqueness result) for the backward (resp. forward) adjoint problem associated with the nonlinear system. Our method also applies to obtain results of existence or uniqueness for some linear hyperbolic systems with discontinuous coeecients.
On-Orbit Geometric Calibration Model and Its Applications for High-Resolution Optical Satellite Imagery

On-orbit geometric calibration is a key technology to guarantee the geometric quality of high-resolution optical satellite imagery. In this paper, we present an approach for the on-orbit geometric calibration of high-resolution optical satellite imagery, focusing on two core problems: constructing an on-orbit geometric calibration model and proposing a robust calculation method. First, a rigorous geometric imaging model is constructed based on the analysis of the major error sources. Second, we construct an on-orbit geometric calibration model through performing reasonable optimizing and parameter selection of the rigorous geometric imaging model. On this basis, the calibration parameters are partially calculated with a stepwise iterative method by dividing them into two groups: external and internal calibration parameters. Furthermore, to verify the effectiveness of the proposed calibration model and methodology, on-orbit geometric calibration experiments for ZY1-02C panchromatic camera and ZY-3 three-line array camera are conducted using the reference data of the Songshan calibration test site located in the Henan Province, China. The experimental results demonstrate a certain deviation of the on-orbit calibration result from the initial design values of the calibration parameters. Therefore, on-orbit geometric calibration is necessary for optical satellite imagery. On the other hand, by choosing multiple images, which cover different areas and are acquired at different points in time to verify their geometric accuracy before and after calibration, we find that after on-orbit geometric calibration, the geometric accuracy of these images without ground control points is significantly OPEN ACCESS Remote Sens. 2014, 6 4392 improved. Additionally, due to the effective elimination of the internal distortion of the camera, greater geometric accuracy was achieved with less ground control points than before calibration.
Association of the recurrence of vocal leukoplakia with MDM2-309 variants over a 2-year period: a prospective study.

CONCLUSION
MDM2-309 polymorphism variant genotypes decrease the risk of recurrence in vocal leukoplakia.


OBJECTIVE
The results of a previous study 2 years ago showed the effect of mouse double minute 2 homolog (MDM2) SNP309 polymorphisms in people with laryngeal carcinoma and vocal leukoplakia (a pre-cancerous laryngeal carcinoma lesion). This prospective, clinical trial was performed to assess the relationship between MDM2-309 polymorphism variants and recurrence/cancerization rates in people with vocal leukoplakia over a 2-year period.


PARTICIPANTS AND METHOD
A total of 61 post-operative patients with vocal leukoplakia participated in this prospective, observational, 2-year, follow-up study, and were genotyped for the MDM2-309 gene using pyrosequencing. Recurrence and cancerization rates were used to assess the relationship between the clinical outcome and the genotype variants.


RESULTS
The recurrence rate in the GT genotypes group was lower than that in the normal TT genotype group (17.2% vs 50%, p = 0.05) and there was a significantly lower recurrence rate in the GG genotype group than in the normal TT genotype group (10% vs 50%, p = 0.03). However, there was no statistically significant difference in the cancerization rate between the MDM2-309 variant (GT + GG) genotypes group and the normal TT genotype group (12.2% vs 8.3%, p > 0.05) over the 2-year follow-up period.
A CD8 T Cell/Indoleamine 2,3-Dioxygenase Axis Is Required for Mesenchymal Stem Cell Suppression of Human Systemic Lupus Erythematosus

OBJECTIVE
Allogeneic mesenchymal stem cells (MSCs) exhibit therapeutic effects in human autoimmune diseases such as systemic lupus erythematosus (SLE), but the underlying mechanisms remain largely unknown. The aim of this study was to investigate how allogeneic MSCs mediate immunosuppression in lupus patients.


METHODS
The effects of allogeneic umbilical cord-derived MSCs (UC-MSCs) on inhibition of T cell proliferation were determined. MSC functional molecules were stimulated with peripheral blood mononuclear cells from healthy controls and SLE patients and examined by real-time polymerase chain reaction. CD4+ and CD8+ T cells were purified using microbeads to stimulate MSCs in order to determine cytokine expression by MSCs and to further determine which cell subset(s) or which molecule(s) is involved in inhibition of MSC-mediated T cell proliferation. The related signaling pathways were assessed. We determined levels of serum cytokines in lupus patients before and after UC-MSC transplantation.


RESULTS
Allogeneic UC-MSCs suppressed T cell proliferation in lupus patients by secreting large amounts of indoleamine 2,3-dioxygenase (IDO). We further found that interferon-γ (IFNγ), which is produced predominantly by lupus CD8+ T cells, is the key factor that enhances IDO activity in allogeneic MSCs and that it is associated with IFNGR1/JAK-2/STAT signaling pathways. Intriguingly, bone marrow-derived MSCs from patients with active lupus demonstrated defective IDO production in response to IFNγ and allogeneic CD8+ T cell stimulation. After allogeneic UC-MSC transplantation, serum IDO activity increased in lupus patients.


CONCLUSION
We found a previously unrecognized CD8+ T cell/IFNγ/IDO axis that mediates the therapeutic effects of allogeneic MSCs in lupus patients.
Detecting short periods of elevated workload: A comparison of nine workload assessment techniques

The present experiment tested the merits of 9 common workload assessment techniques with relatively short periods of workload in a car-driving task. Twelve participants drove an instrumented car and performed a visually loading task and a mentally loading task for 10,30, and 60 s. The results show that 10-s periods of visual and mental workload can be measured successfully with subjective ratings and secondary task performance. With respect to longer loading periods (30 and 60 s), steering frequency was found to be sensitive to visual workload, and skin conductance response (SCR) was sensitive to mental workload. The results lead to preliminary guidelines that will help applied researchers to determine which techniques are best suited for assessing visual and mental workload.
Privacy as information access and illusory control: The case of the Facebook News Feed privacy outcry

Increasingly, millions of people, especially youth, post personal information in online social networks (OSNs). In September 2006, one of the most popular sites—Facebook.com—introduced the features of News Feed and Mini Feed, revealing no more information than before, but resulting in immediate criticism from users. To investigate the privacy controversy, we conducted a survey among 172 current Facebook users in a large US university to explore their usage behaviors and privacy attitudes toward the introduction of the controversial News Feed and Mini Feed features. We examined the degree to which users were upset by the changes, explored the reasons as to why, and examined the influences of the News Feed privacy outcry on user behavior changes. The results have demonstrated how an easier information access and an ‘‘illusory” loss of control prompted by the introduction of News Feed features, triggered users’ privacy concerns. In addition to enhancing our theoretical understanding of privacy issues in the online social networks, this research is also potentially useful to privacy advocates, regulatory bodies, service providers, and marketers to help shape or justify their decisions concerning the online social networks. 2009 Elsevier B.V. All rights reserved.
Mediterranean diet, traditional risk factors, and the rate of cardiovascular complications after myocardial infarction: final report of the Lyon Diet Heart Study.

BACKGROUND
The Lyon Diet Heart Study is a randomized secondary prevention trial aimed at testing whether a Mediterranean-type diet may reduce the rate of recurrence after a first myocardial infarction. An intermediate analysis showed a striking protective effect after 27 months of follow-up. This report presents results of an extended follow-up (with a mean of 46 months per patient) and deals with the relationships of dietary patterns and traditional risk factors with recurrence.


METHODS AND RESULTS
Three composite outcomes (COs) combining either cardiac death and nonfatal myocardial infarction (CO 1), or the preceding plus major secondary end points (unstable angina, stroke, heart failure, pulmonary or peripheral embolism) (CO 2), or the preceding plus minor events requiring hospital admission (CO 3) were studied. In the Mediterranean diet group, CO 1 was reduced (14 events versus 44 in the prudent Western-type diet group, P=0.0001), as were CO 2 (27 events versus 90, P=0.0001) and CO 3 (95 events versus 180, P=0. 0002). Adjusted risk ratios ranged from 0.28 to 0.53. Among the traditional risk factors, total cholesterol (1 mmol/L being associated with an increased risk of 18% to 28%), systolic blood pressure (1 mm Hg being associated with an increased risk of 1% to 2%), leukocyte count (adjusted risk ratios ranging from 1.64 to 2.86 with count >9x10(9)/L), female sex (adjusted risk ratios, 0.27 to 0. 46), and aspirin use (adjusted risk ratios, 0.59 to 0.82) were each significantly and independently associated with recurrence.


CONCLUSIONS
The protective effect of the Mediterranean dietary pattern was maintained up to 4 years after the first infarction, confirming previous intermediate analyses. Major traditional risk factors, such as high blood cholesterol and blood pressure, were shown to be independent and joint predictors of recurrence, indicating that the Mediterranean dietary pattern did not alter, at least qualitatively, the usual relationships between major risk factors and recurrence. Thus, a comprehensive strategy to decrease cardiovascular morbidity and mortality should include primarily a cardioprotective diet. It should be associated with other (pharmacological?) means aimed at reducing modifiable risk factors. Further trials combining the 2 approaches are warranted.
The challenge of indication extrapolation for infliximab biosimilars.

A biosimilar is intended to be highly similar to a reference biologic such that any differences in quality attributes (i.e., molecular characteristics) do not affect safety or efficacy. Achieving this benchmark for biologics, especially large glycoproteins such as monoclonal antibodies, is challenging given their complex structure and manufacturing. Regulatory guidance on biosimilars issued by the U.S. Food and Drug Administration, Health Canada and European Medicines Agency indicates that, in addition to a demonstration of a high degree of similarity in quality attributes, a reduced number of nonclinical and clinical comparative studies can be sufficient for approval. Following a tiered approach, clinical studies are required to address concerns about possible clinically significant differences that remain after laboratory and nonclinical evaluations. Consequently, a critical question arises: can clinical studies that satisfy concerns regarding safety and efficacy in one condition support "indication extrapolation" to other conditions? This question will be addressed by reviewing the case of a biosimilar to infliximab that was approved recently in South Korea, Europe, and Canada for multiple indications through extrapolation. The principles discussed should also apply to biosimilars of other monoclonal antibodies that are approved to treat multiple distinct conditions.
Positive characteristic Manin-Mumford theorem

We prove a version of the Manin-Mumford conjecture for semiabelian varieties over fields of positive characteristic. The proof presented here contains the details of the proof sketched by the author in the article "Diophantine geometry from model theory," BSL 7 (2001) no. 1, 37 - 57; using the model theory of difference fields along the lines of Hrushovski. Algebraic proofs have been presented by Pink & Roessler and Pillay.
Psychometric evaluation of the Stroke Impact Scale 3.0.

BACKGROUND
The Stroke Impact Scale 3.0 (SIS 3.0) is widely used to measure quality of life in stroke survivors; however, previous studies have not tested the original 8-factor structure of the scale. In addition, previous studies have shown floor and ceiling effect and weak reliability within the scale.


OBJECTIVE
The aim of this study was to evaluate the psychometric characteristics of the SIS 3.0, including its construct validity (factorial structure, concurrent and contrasting group validity), floor and ceiling effect, and reliability.


METHOD
A cross-sectional design was used to study 392 stroke survivors enrolled in 16 rehabilitation facilities across Italy. Factorial structure of the SIS 3.0 was tested with confirmatory factor analysis. Concurrent and contrasting group validities were evaluated with other scales measuring functional capacities, neurological functions, cognition, anxiety, depression, and generic quality of life. Floor and ceiling effects were evaluated by determining the percentages of patients with the minimum and the maximum score at SIS 3.0. Reliability was determined by Cronbach's α and test-retest.


RESULTS
Participants were 71 years old on average (SD, 11 years); 55% were men. Confirmatory factor analysis revealed a new 4-factor structure that fitted the data better than the original 8-factor structure did. Concurrent and contrasting group validity of the new 4-factor structure was supportive and no floor and ceiling effects were found. Internal consistency and test-retest reliability ranged between 0.79 and 0.98.


CONCLUSION
The new factorial structure of the SIS 3.0 with 4 factors showed better psychometric properties than the original 8-factor structure did. This evidence supports further use of the SIS 3.0 in clinical practice and research.
Activity-based costing / management and its implications for operations management

Activity-Based Costing/Management (ABC/M) is an Information System developed in the 1980s to overcome some of the limitations of traditional cost accounting and to enhance its usefulness to strategic decision-making. In this paper, we show how an ABC/M system can serve as a useful information system to support effective operations decision-making processes. We propose a conceptual framework, Operations Hexagon, to discuss the managerial implications of an ABC/M system for various operations management decisions related to product planning and design, quality management and control, inventory management, capacity management and work force management. By viewing an ABC/M system as an enabler to improve the operations decision-making, we demonstrate that these systems enable an operations manager to enhance the quality of the decision-making process.  2001 Elsevier Science Ltd. All rights reserved.
Creation of spiking neuron models applied in pattern recognition problems

Some spiking neuron models have proved to solve different linear and non-linear pattern recognition problems. Indeed, only one spiking neuron can generate comparable results as classical artificial neural network. However, depending on the classification problem, one spiking model could be better or less efficient than other. In this paper we propose a methodology to create spiking neuron models using Gene Expression Programming. The new models created are applied in eight pattern recognition problems. The results obtained are compared with previous results generated adopting the Izhikevich spiking neuron model. This first effort will help us to generate spiking neuron models which will be adaptable to a specific pattern recognition problem.
Evaluation of Land Administration Systems

Currently there are no internationally accepted methodologies to evaluate and compare the performance of land administration systems. This is partly because land administration systems are in constant reform, and probably more importantly, they represent societies' different perceptions of land. This paper describes the development of a framework to measure and compare the performance of land administration systems. The research is of particular relevance since it develops a management model which links the operational aspects of land administration with land policy.