LLukas22/scidocs huggingface dataset:
Single-CDTA (Current Differencing Transconductance Amplifier) Current-Mode Biquad Revisited

This paper presents a current-mode (CM) second-order filter, employing one so-called “Z Copy – Current Differencing Transconductance Amplifier” (ZC-CDTA), two grounded capacitors, and one virtually grounded resistor. The filter provides two current outputs of low-pass (LP) and band-pass (BP) types for driving independent loads, and one high-pass (HP) current output, flowing through one of the working capacitors. Other implementations of various types of transfer functions are proposed by means of commonly used methods of input/output current summing. Their critical analysis is accomplished from the point of view of tracking errors and dynamic range optimization. Results of the PSpice simulation, which utilizes the CDTA model on the level of CMOS transistor structure, are enclosed.
Modeling for control of HCCI engines

The goal of this work is to accurately predict the phasing of HCCI combustion for a single cylinder research engine using variable valve actuation (VVA) at Stanford University. Three simple single-zone models were developed and compared with experiment. The difference between the three modeling approaches centered around the combustion chemistry mechanism used in each. The first modeling approach, which utilized a temperature threshold to model the onset of the combustion reaction, did not work well. However, an integrated reaction rate threshold accounting for both the temperature and concentration did correlate well with experiment. Additionally, another model utilizing a simple two-step kinetic mechanism also showed good correlation with experimental combustion phasing.
Findings of the 2017 Conference on Machine Translation (WMT17)

This paper presents the results of the WMT17 shared tasks, which included three machine translation (MT) tasks (news, biomedical, and multimodal), two evaluation tasks (metrics and run-time estimation of MT quality), an automatic post-editing task, a neural MT training task, and a bandit learning task.
Myopic optic disc tilt and the characteristics of peripapillary retinal nerve fiber layer thickness measured by spectral-domain optical coherence tomography.

PURPOSE
To investigate the correlation between myopic optic disc tilt and the characteristics of peripapillary retinal nerve fiber layer (RNFL) thickness measured by Cirrus HD spectral-domain optical coherence tomography (Cirrus HD OCT; Carl Zeiss Meditec, Dublin, CA).


METHODS
A total of 255 eyes of 255 healthy young male participants with various degrees of refractive errors (mean spherical equivalent, -3.17 ± 2.40 D; range, -11.00 to 0.00 D) underwent ophthalmic examinations, including refractive error, axial length, and optic disc area measurement. The degree of horizontal/vertical optic disc tilt was evaluated by cross-sectional images obtained by the Cirrus HD OCT. The average, superior, nasal, inferior, and temporal quadrant thickness and superior/inferior peak locations of the peripapillary RNFL were also measured with the Cirrus HD OCT.


RESULTS
On the univariate analysis, eyes with more temporally tilted optic discs (horizontal tilt) had higher myopia, greater axial length, a thinner average, superior, nasal, and inferior RNFL, thicker temporal RNFL, and more temporally positioned superior/inferior peak locations (all P values <0.001). The degree of inferior optic disc tilt (vertical tilt) was associated with high myopia and a more temporally positioned inferior peak location (all P values <0.05). On multivariate analysis, eyes with more temporally tilted optic discs had a thicker temporal RNFL and more temporally positioned superior/inferior peak locations.


CONCLUSIONS
The characteristics of the peripapillary RNFL thickness were associated with the degree of myopic optic disc tilt, especially in the temporal area. The degree of myopic optic disc tilt should be considered when interpreting the RNFL thickness measured by the Cirrus HD OCT.
Design Version Management

Systems for version management have been in existence for some time, yet no system provides the complete range of services needed to control the versions and configurations of a complex design as it evolves over time. The authors have been developing a system, called a version server, to provide just these services. It supports an object -oriented model for organizing design data and provides operational mechanisms for controlling the design's evolution, such as object check-in/checkout and a validation subsystem.
Mangrove forests store high densities of carbon across the tropical urban landscape of Singapore

Tropical forested ecosystems provide multiple ecosystem services to rural and urban landscapes, with carbon storage gaining particular attention. Deforestation due to rural-urban transitions may lead to a reduction in carbon storage ability. Coastal mangrove forests are particularly at risk from deforestation due to their location in the rapidly urbanizing coastal zone, and the city state of Singapore is an extreme example, losing as much as 90 % of its original mangrove cover due to land reclamation and reservoir construction. Knowledge of mangrove ecosystem services may allow better conservation, restoration and incorporation of remaining mangrove patches into the urban landscape. Focusing on the regulating ecosystem service of carbon storage, mangrove carbon stocks have been estimated for Singapore using a combination of field and remote sensing techniques. Biomass carbon showed substantial spatial variation, with old, contiguous mangrove patches containing a higher density of biomass carbon than fragmented, river-fringing or restored mangroves. In total, national biomass carbon equated to 116,117.1 megagrams of carbon (Mg C), and a coarse estimate of the total carbon stock (including soil carbon) suggests that Singapore’s mangroves may store 450,571.7 Mg C. While lower than other regional estimates focused on natural, oceanic mangroves, this is a significant carbon stock for a disturbed, urban mangrove system, and may be equivalent to the average annual carbon emissions of 621,000 residents. This analysis, alongside a review of other urban forest studies, highlights the importance of forested ecosystems such as mangroves in providing a carbon storage ecosystem service to urban areas.
Women's attractiveness judgments of self-resembling faces change across the menstrual cycle

Two lines of reasoning predict that women's preferences for people exhibiting cues to kinship will be lower in the follicular phase than in the luteal phase of the menstrual cycle. Women may avoid kinship cues during the follicular phase when they are most fertile due to the costs of inbreeding. Alternatively, women may seek kinship cues during the luteal phase as a byproduct of the benefits of associating with kin during pregnancy, which is also characterized by high progesterone. We find that preferences for facial resemblance, a putative kinship cue, follow this predicted pattern and are positively correlated with estimated progesterone levels based on cycle day. Neither estimated estrogen levels nor conception risk predicted preferences for self-resemblance, and the cyclic shift was stronger for preferences for female faces than male faces. These findings lead to the possibility that this cyclic change in preference for self-resemblance may be a byproduct of a hormonal mechanism for increasing affiliative behavior toward kin during pregnancy rather than a mechanism for preventing inbreeding during fertile periods.
Phosphate removal with several thrice-weekly dialysis methods in overweight hemodialysis patients.

BACKGROUND
Currently available phosphate binders are associated with either hypercalcemia or high costs, which limit their use in hemodialysis patients. Whether modifying dialysis prescription to intensify small-solute clearance also leads to better phosphate clearance is unknown.


STUDY DESIGN
Randomized crossover trial.


PARTICIPANTS
Large patients (>80 kg; N = 18) who could not achieve adequate Kt/V during a standard 4-hour thrice-weekly prescription of maintenance hemodialysis.


INTERVENTION
2 high-flux dialyzers in parallel for 4 hours in comparison to 3 other dialysis modalities (4 hours of standard hemodialysis, 4.5 hours of hemodialysis, and 4 hours of hemodialysis with increased dialysate flow).


OUTCOMES
(1) Predialysis serum phosphate level, (2) postdialysis phosphate level, (3) phosphate clearance, and (4) phosphate removal, all assessed during the last midweek session for each of the 4 different modalities.


RESULTS
Mean baseline predialysis serum phosphate level was 5.95 +/- 1.95 mg/dL. Using 2 dialyzers in parallel was associated with a significant decrease in predialysis serum phosphate level compared with standard hemodialysis (1.33 mg/dL lower; P = 0.01). Mean serum postdialysis serum phosphate levels during the last treatment of the double-dialyzer period were also lower by 0.43 and 0.74 mg/dL than during the last treatment of the standard-hemodialysis (P = 0.05) and increased-dialysate-flow (P < 0.001) periods, respectively. The double-dialyzer strategy also was associated with greater phosphate clearance (177.2 [corrected] mL/min; 95% confidence interval [CI], 158.6 to 195.9) [corrected] than the other 3 strategies (129.8 [corrected] mL/min; 95% CI, 111.2 to 148.4; 135.4 mL/min; 95% CI, 115.4 to 155.3; and 131.2 mL/min; 95% CI, 112.0 to 150.4), [corrected] but not greater phosphate removal.


LIMITATIONS
Small sample size, short study duration, and results of phosphate removal analysis inconclusive.


CONCLUSION
Use of 2 dialyzers in parallel for 6 weeks in overweight hemodialysis patients led to substantially lower predialysis phosphate levels. Future studies should explore the potential contribution of increased dialyzer surface area to better control of serum phosphate levels in maintenance hemodialysis patients.
Library Guides: Civil Engineering Graduate Student Orientation: About the Library

A collection of resources useful to graduate students in Civil Engineering, Environmental Engineering, and Building Construction and Management 193
An Infinite Hidden Markov Model for Short-term Interest Rates ∗

The time-series dynamics of short-term interest rates are important as they are a key input into pricing models of the term structure of interest rates. In this paper we extend popular discrete time short-rate models to include Markov switching of infinite dimension. This is a Bayesian nonparametric model that allows for changes in the unknown conditional distribution over time. Applied to weekly U.S. data we find significant parameter change over time and strong evidence of non-Gaussian conditional distributions. Our new model with an hierarchical prior provides significant improvements in density forecasts as well as point forecasts. We find evidence of recurring regimes as well as structural breaks in the empirical application. key words: hierarchical Dirichlet process prior, beam sampling, Markov switching, MCMC JEL: C58, C14, C22, C11 ∗We are grateful for helpful comments from Yong Song and seminar participants at the University of Toronto. Maheu thanks the SSHRC for financial support. †DeGroote School of Business, McMaster University, 1280 Main Street W., Hamilton, ON, Canada, L8S4M4 and University of Toronto, Canada and RCEA, Italy, maheujm@mcmaster.ca ‡Department of Economics, University of Toronto, bill.yang@mail.utoronto.ca
Scientific Representation: Paradoxes of Perspective

Preface Introduction: the 'picture theory of science' PART ONE: REPRESENTATION 1.1 Representation of, Representation as 1.2 Imaging, Picturing, and Scaling 1.3 Pictorial Perspective and the Indexical PART TWO. WINDOWS, ENGINES, AND MEASUREMENT 2.1 A Window on the Invisible World (?) 2.2 The Problem of Coordination 2.3 Measurement as Representation (1) The Physical Correlate 2.4 Measurement as Representation (2) Information PART THREE. STRUCTURE AND PERSPECTIVE 3.1 From the Bildtheorie of science to paradox 3.2 The Longest Journey: Bertrand Russell 3.3 Carnap's Lost World and Putnam's Paradox 3.4 An Empiricist Structuralism PART FOUR. APPEARANCE AND REALITY 4.1 Appearance vs. Reality in the Sciences 4.2 Rejecting the Appearance from Reality Criterion APPENDICES BIBLIOGRAPHY NOTES
Effects of phenytoin sodium on dura mater healing in a rat model of CSF leakage.

AIM
Cerebro-spinal fluid (CSF) leakage caused by defects on the dura mater after trauma or some neurosurgical interventions is an important issue. In this study, we investigated the effects of local and systemic use of phenytoin sodium on dural healing.


MATERIAL AND METHODS
Thirty-six male Wistar rats were divided into control, local phenytoin and systemic phenytoin groups with 12 rats in each. For each group, a dura defect was created at thoracic segment. Subjects were sacrificed at following 1st and 6th weeks and damaged segments were isolated. The results were compared histopathologically by Hematoxylin-Eosin and Masson-Trichrome staining. Criteria for the rate of collagen, neovascularization, and granulation formation were assessed semi quantitatively according to the histological assessment scale modified by Ozisik et al.


RESULTS
Better healing was achieved in the systemic and local phenytoin groups than in the control group. The level of healing was significantly higher in the systemic group in both early and late periods than in other groups (p < 0.01). The level of healing in the late-local group was also statistically significantly higher than that in the control group.


CONCLUSION
We observed that both systemic and local uses of phenytoin sodium (especially systemic) have positive effects on dura healing.
Improving cycle control in progestogen-only contraceptive pill users by intermittent treatment with a new anti-progestogen.

BACKGROUND
The safety and efficacy of the anti-progestogen Org 31710 in improving cycle control in healthy women using the desogestrel progestogen-only pill was investigated in this randomized, double-blind, placebo-controlled study.


METHODS
A total of 103 women using the 75 micro g desogestrel progestogen-only pill daily also received either 150 mg Org 31710 or placebo once every 28 days, starting on day 1, for a duration of 4-7 treatment cycles.


RESULTS
The percentage of women with bleeding or spotting (B/S) every day in the placebo group was on average 30% during the whole treatment period and no days without reported B/S occurred. In contrast, a cyclic pattern was observed for the Org 31710 group; a peak incidence of B/S was observed on day 3 or 4 of each cycle, followed by a sharp decrease on cycle days 9-15. Compared with controls, less subjects in the Org 31710 group reported irregular, frequent or prolonged bleeding. These differences were clearly observed in the initial cycles, but were somewhat less pronounced during the later cycles of the treatment period. A relatively high incidence of B/S episodes starting in the second section of the cycle was also observed.


CONCLUSION
The addition of Org 31710 once a month improved cycle control in women using daily treatment with 75 micro g desogestrel.
Esophagogastric Junction Morphology Predicts Susceptibility to Exercise-Induced Reflux

BACKGROUND AND AIM:Although strenuous exercise has been reported to increase gastroesophageal reflux, there are few data exploring the mechanism behind this relationship. The aim of this study was to use vigorous exercise as a provocation for strain-induced reflux and examine the correlation between endoscopically assessed EGJ integrity and exercise-induced reflux.METHODS:Ten controls and 10 GERD patients were studied for a 2-day period using the wireless Bravo™ pH monitoring system. The subjects were randomly assigned to perform 60 min of exercise on day 1 or 2 consuming the same diet on both days. Exercise consisted of 30 min of running and 30 min of 5 resistance exercises. Subjects underwent endoscopy to grade the EGJ “flap valve” and manometry to measure basal LES pressure.RESULTS:Nineteen subjects completed the 2-day study with 100% data capture during exercise. Median acid exposure was increased more than threefold for both controls and GERD patients during exercise when compared to nonexercise periods. In addition, a strong correlation existed between EGJ grade and % time pH < 4 during exercise while there was not a significant correlation between LES pressure and EGJ grade. These findings were present even after exclusion of hiatus hernia patients (flap valve grade 4).CONCLUSIONS:Exercise caused a threefold increase in esophageal acid exposure in both controls and GERD patients. The degree of exercise-induced reflux is strongly correlated with EGJ morphology and this supports the hypothesis that anatomical integrity of the EGJ is of cardinal importance in preventing strain-induced reflux.
Pain Paroxysms With Coronal Radiation: Case Series and Proposal of a New Variant of Epicrania Fugax.

OBJECTIVE
We aim to report 4 patients with brief pain paroxysms whose clinical features remind of typical epicrania fugax (EF), except for the direction along a transverse trajectory.


BACKGROUND
EF has been defined as a brief paroxysmal head pain, with stabbing quality, describing a linear or zig-zag trajectory across the surface of one hemicranium.


METHODS
We considered all patients attending the headache outpatient office at 3 tertiary hospitals from March 2008 to December 2015. We identified a total of 4 cases with dynamic pain paroxysms moving in coronal direction.


RESULTS
The mean age at onset was 49 years (range 34-75). All the patients suffered a dynamic pain from parietal or temporal areas to the contralateral ones, crossing the midline in a linear or zig zag trajectory, the entire sequence lasting 2-3 seconds. No triggers were identified. One patient noticed mild interictal tenderness at the stemming point. The frequency of the attacks varied from 2 per week to 1 every 2 months. No underlying disorders were identified by physical and neurological exams and neuroimaging and laboratory tests.


CONCLUSIONS
Our patients presented with a paroxysmal head pain that might correspond to a transverse variant of EF. These observations may not only expand the EF phenotype but also reinforce the distinction between EF and pericranial neuralgias.
Anterior cruciate ligament injury and ankle dorsiflexion

The aim was to study whether the degree of ankle dorsiflexion differs between subjects with an anterior cruciate ligament (ACL) injury and uninjured controls. Another aim was to study ankle dorsiflexion between the injured and the uninjured leg and in addition between women and men with an ACL injury. Sixty subjects (ACL injury, n = 30 and controls, n = 30) were enroled consecutively at two physical therapy settings. Ankle dorsiflexion was measured with a goniometer in a standardized way in a weight-bearing lunge position. Repeated-measures ANOVA revealed a significant difference (p < 0.001) in ankle dorsiflexion between subjects with an ACL injury (mean 41.1° SD 5.7) and those without (mean 46.6° SD 5.3). No difference in ankle dorsiflexion was found between the injured leg and the uninjured or between women and men with ACL injury. The present findings suggest lower degree of ankle dorsiflexion in subjects with an ACL injury than in uninjured controls. A functional test measuring ankle dorsiflexion with a goniometer may be one way of identifying individuals at increased risk of ACL injury. Comparative study, Level II.
Ontological Pathfinding

Recent years have seen a drastic rise in the construction of web-scale knowledge bases (e.g., Freebase, YAGO, DBPedia). These knowledge bases store structured information about real-world people, places, organizations, etc. However, due to limitations of human knowledge and information extraction algorithms, these knowledge bases are still far from complete. In this paper, we study the problem of mining first-order inference rules to facilitate knowledge expansion. We propose the Ontological Pathfinding algorithm (OP) that scales to web-scale knowledge bases via a series of parallelization and optimization techniques: a relational knowledge base model to apply inference rules in batches, a new rule mining algorithm that parallelizes the join queries, a novel partitioning algorithm to break the mining tasks into smaller independent sub-tasks, and a pruning strategy to eliminate unsound and resource-consuming rules before applying them. Combining these techniques, we develop the first rule mining system that scales to Freebase, the largest public knowledge base with 112 million entities and 388 million facts. We mine 36,625 inference rules in 34 hours; no existing approach achieves this scale.
Self-collection for high-risk HPV detection in Brazilian women using the careHPV™ test.

OBJECTIVE
Cervical cancer is the second most common cancer among Brazilian women. High-risk human papillomavirus (hr-HPV) persistence is the primary cause of cervical neoplasia. Early detection of hr-HPV is important for identifying women at risk for developing cervical lesions. Approximately 85% of new cases of cervical cancer worldwide and 50% of the total cervical cancer deaths occurred in developing countries. Here, a new methodology to support a cervical cancer screening program was evaluated in women from various Brazilian regions.


METHODS
Two thousand women aged 18-77 years were enrolled in an opportunistic cervical cancer screening program and were randomized into self-vaginal or health professional-guided cervical sampling groups. The Qiagen careHPV™ test was performed on all samples. Pap tests were performed on all women using liquid-based cytology.


RESULTS
Positive hr-HPV results were obtained in 12.3% (245/2000) of women; similar rates were observed in self- or health professional-collected samples. Eighty-nine percent (1719/2000) of cervical cytologies classified as normal were negative to hr-HPV. Among the cytological samples, 36.6% classified as ASC-US+ were positive to hr-HPV, 78.8% were LSIL and 75.0% were HSIL.


CONCLUSIONS
Self-sampled and health professional-sampled vaginal/cervical specimens did not differ in their rates of detection of hr-HPV. Therefore, HPV DNA testing in self-sampled vaginal cells is an alternative to primary screening in low-resource settings.