LLukas22/scidocs huggingface dataset:
Analysing the visual dynamics of spatial morphology

Recently there has been a revival of interest in visibility analysis of architectural configurations. The new analyses rely heavily on computing power and statistical analysis, two factors which, according to the postpositivist school of geography, should immediately cause us to be wary. The danger, they would suggest, is in the application of a reductionist formal mathematical description in order to `explain' multilayered sociospatial phenomena. The author presents an attempt to rationalise how we can use visibility analysis to explore architecture in this multilayered context by considering the dynamics that lead to the visual experience. In particular, it is recommended that we assess the visual process of inhabitation, rather than assess the visibility in vacuo. In order to investigate the possibilities and limitations of the methodology, an urban environment is analysed by means of an agent-based model of visual actors within the configuration. The results obtained from the model are compared with actual pedestrian movement and other analytic measurements of the area: the agents correlate well both with human movement patterns and with configurational relationship as analysed by space-syntax methods. The application of both methods in combination improves on the correlation with observed movement of either, which in turn implies that an understanding of both the process of inhabitation and the principles of configuration may play a crucial role in determining the social usage of space. DOI:10.1068/b12962
End-effector Position Analysis of SCORBOT-ER Vplus Robot

This paper features the kinematic analysis of a SCORBOT-ER Vplus robot arm which is used for doing successful robotic manipulation task in its workspace. The SCORBOT-ER Vplus is a 5-dof vertical articulated robot and all the joints are revolute [1]. The kinematics problem is defined as the transformation from the Cartesian space to the joint space and vice versa. The Denavit-Harbenterg (D-H) model of representation is used to model robot links and joints in this study along with 4x4 homogeneous matrix. SCORBOT-ER Vplus is a dependable and safe robotic system designed for laboratory and training applications. This versatile system allows students to gain theoretical and practical experience in robotics, automation and control systems. The MATLAB 8.0 is used to solve this mathematical model for a set of joint parameter.
Magnetometer Calibration for Portable Navigation Devices in Vehicles Using a Fast and Autonomous Technique

Using absolute navigation systems (such as global navigation satellite systems) has proved to be insufficient for indoor navigation or when navigating in urban canyons due to multipath and obstruction. This opened the gate widely for sensor-based navigation systems to be used, particularly after the development of low-cost microelectromechanical system sensors. Heading determination is one of the most important aspects for navigation solutions. Magnetometer is a low-cost sensor that can provide an absolute heading from magnetic north by sensing the Earth's magnetic field. Magnetometer readings are usually affected by magnetic fields, other than the Earth's magnetic field, and by other error sources; therefore, magnetometer calibration is required. In this paper, a technique is proposed for fast and automatic magnetometer calibration that requires small space coverage. There is no user involvement in the calibration process, and there are no required specific movements. The proposed technique performs 3-D-space magnetometer calibration using 2-D calibration equations with pitch and roll sectors. The 3-D-space is divided into a group of pitch and roll sectors. Inside each sector, 2-D calibration can be performed for the leveled magnetometer readings, which make the calibration process faster and requiring less data. This technique makes the magnetometer useful for determining heading in pseudo-tethered devices, particularly when used while driving. Pseudo-tethered navigation devices are tethered at normal operation, but they can change their orientation according to user needs such as portable vehicle navigation devices, which can be placed on the dashboard of a vehicle or attached to the wind shield.
A Neural Representation of Sketch Drawings

We present sketch-rnn, a recurrent neural network (RNN) able to construct stroke-based drawings of common objects. The model is trained on thousands of crude human-drawn images representing hundreds of classes. We outline a framework for conditional and unconditional sketch generation, and describe new robust training methods for generating coherent sketch drawings in a vector format.
Improving the IATA delay data coding system for enhanced data analytics

Aviation delays inconvenience travelers and result in financial losses for stakeholders. Without complex data pre-processing, delay data collected by the existing IATA delay coding system are inadequate to support advanced delay analytics, e.g. large-scale delay propagation tracing in an airline network. Consequently, we developed three new coding schemes aiming at improving the current IATA system. These schemes were tested with specific analysis tasks using simulated delay data and were benchmarked against the IATA system. It was found that a coding scheme with a well-designed reporting style can facilitate automated data analytics and data mining, and an improved grouping of delay codes can minimise potential confusion at the data entry and recording stages. © 2014 Elsevier Ltd. All rights reserved.
Effects of probiotics in patients with diabetes mellitus type 2: study protocol for a randomized, double-blind, placebo-controlled trial

BACKGROUND
Low grade chronic inflammation is observed in patients with type 2 diabetes mellitus (T2DM). Endotoxin derived from gut bacteria may act as a potent inflammatory stimulant. Probiotics, which are believed to contain health promoting live microorganisms, may influence circulating endotoxin levels. Ingestion of live probiotic cultures may alter gut microbiota in a beneficial manner to reduce inflammation; no information is available whether or not they do so in patients with T2DM. Therefore, the aim of this study is to characterize the beneficial effects of probiotics on circulating endotoxin levels and other biomarkers related to systemic low-grade inflammation in patients with T2DM.


METHODS
One hundred and twenty consenting adult Saudi T2DM patients (naïve or newly diagnosed and without co-morbidities) will be enrolled in this clinical trial and randomized to receive daily placebo or probiotics (Ecologic®Barrier) for 26 weeks in a double-blind manner. Inflammatory and metabolic markers will be measured and fecal samples analyzed. Measurements/samples will be obtained at baseline and after 4, 8, 12/13 and 26 weeks of treatment.


DISCUSSION
It is expected that the probiotic product will induce beneficial changes in gut microbiota, reduce the systemic inflammatory state through altering systemic endotoxin levels and, as such, reduce the systemic inflammatory response observed in T2DM subjects.


TRIAL REGISTRATION
ClinicalTrials.gov Identifier: NCT01765517.
Performance of the AlGaN HEMT structure with a gate extension

The microwave performance of AlGaN/GaN HEMTs at large drain bias is reported. The device structures were grown by organometallic vapor phase epitaxy on SiC substrates with a channel sheet resistance less than 280 ohms/square. The breakdown voltage of the HEMT was improved by the composite gate structure consisting of a 0.35 /spl mu/m long silicon nitride window with a 0.18 /spl mu/m long metal overhang on either side. This produced an metal-insulator-semiconductor (MIS) gate extension toward the drain with the insulator, silicon nitride, approximately 40-nm-thick. Transistors with a 150 /spl mu/m total gate width have demonstrated a continuous wave (CW) 10 GHz output power density and power added efficiency of 16.5 W/mm and 47%, respectively when operated at 60 V drain bias. Small-signal measurements yielded an f/sub T/ and f/sub max/ of 25.7 GHz and 48.8 GHz respectively. Maximum drain current was 1.3 A/mm at +4 V on the gate, with a knee voltage of /spl sim/5 V. This brief demonstrates that AlGaN/GaN HEMTs with an optimized gate structure can extend the device operation to higher drain biases yielding higher power levels and efficiencies than have previously been observed.
PO-61 - Patients' Experiences of LIving with CANcer associated thrOmbosis in Spain (PELICANOS).

INTRODUCTION
The Patients' Experiences of LIving with CANcer associated thrombosis (PELICAN) study has identified the experience of cancer-associated thrombosis (CAT) to be a distressing one, for which patients feel ill prepared for and receive insufficient support. However, such data was from a United Kingdom (UK) population and may not be representative of all nationalities, cultures and healthcare systems.


AIM
To explore the experience of cancer associated thrombosis amongst patients living in Spain.


MATERIALS AND METHODS
Twenty consecutive patients with CAT were recruited from a Spanish University Hospital. Where possible spouses were interviews in conjunction. Semi-structured qualitative interviews were undertaken, assited by a pre-agreed promt list. Interviews were audio recorded and transcribed verbatim. Preliminary data analysis was undertaken using thematic analysis.


RESULTS
Several commonalities between UK and Spanish patients were identified including the traumatic nature of the experience, need for information and adaptive behaviors through ritualization. Three new major themes also emerged: Communication needs: over emphasis on heparin injection training, additional need for explanation of cause, response and prognosis The impact of CAT on the concept of self: CAT was considered defining watershed moment, confirmation of seriousness of the cancer, The impact of CAT on the family dynamic: distressing diagnosis for loved ones, exaggerated desire to help which could disempower patient independence.


CONCLUSIONS
The experience of CAT is a distressing one which brings with it additional information needs through effective communication. Within the Spanish population, the role of family is of particular importance as well as the impact of CAT on the patient's feelings of worth and personal identity. Effective communication, support and access to information are essential in order to minimize distress and enhance treatment complicance.
Algorithmic game theory

A new era of theoretical computer science addresses fundamental problems about auctions, networks, and human behavior.
Hyperhidrosis treatment with bornaprine in the acute phase of spinal cord-injured patients

Study design:Original article.Objective:To test the use of bornaprine in the hyperhidrosis treatment in the acute phase of spinal cord-injured patients.Setting:Patients with acute spinal cord lesions in the Spinal Unit of Pietra Ligure, Savona, Italy.Method:In 4 years, 12 patients have been treated, for a maximum period of 75 days, with dosages ranging from 2 to 4 mg day−1.Results:All of them reported long-lasting subjective benefits, without side effects, even after the interruption of the therapy.Conclusion:The bornaprine treatment, at 2 or 4 mg day−1 dosage, has been effective and safe to contrast hyperhidrosis, in the acute phase of spinal cord-injured patients. This positive experience would require additional trials and a larger number of cases to gain a more solid support.
Schema.org: Evolution of Structured Data on the Web

Big data makes common schemas even more necessary.
Pharmaceutical care issues encountered by post-menopausal osteoporotic women prescribed bisphosphonates.

WHAT IS KNOWN AND OBJECTIVE
Pharmacists have been involved in providing comprehensive interventions to osteoporosis patients, but pharmaceutical care issues (PCIs) encountered during such interventions have not been well documented. Therefore, the aim of this study was to document PCIs encountered by post-menopausal osteoporotic women prescribed bisphosphonates.


METHODS
A randomized controlled study was conducted from September 2005-February 2009 in the University Malaya Medical Centre, Malaysia. This main intervention study measured the effects of pharmaceutical care on medication adherence, persistence, quality of life, knowledge and patient satisfaction. However, this manuscript is part of the main intervention study and focuses only on the PCIs encountered.


INCLUSION CRITERIA
post-menopausal women diagnosed with osteoporosis (T-score≤-2·5/low-trauma fracture) and prescribed weekly alendronate/risedronate.


EXCLUSION CRITERIA
those with metabolic bone disease and could not communicate in English. The PCIs identified were collected via personal interviews or telephone calls, and each participant was followed-up for a period of 2 years. All PCIs were discussed with and confirmed by a physician.


RESULTS AND DISCUSSION
Of the 198 participants recruited, 64 (32·3%) experienced adverse effects because of bisphosphonates whereas one participant (0·5%) refused to start bisphosphonates because of fear of adverse effects. Most adverse effects [50 (74·6%)] were reported during the first 3 months of therapy with gastrointestinal problems being the main issue [23 (11·6%)]. Of the nine participants (4·5%) who discontinued bisphosphonates, only three agreed to take another medication. From the 97 PCIs identified, 77 issues could be classified as drug-related problems [according to the Pharmaceutical Care Network Europe Classification v6·2]. There were 87 causes, 178 interventions and 77 outcomes. The main problem and cause of the PCIs encountered were adverse drug events (83·1% and 74·7% respectively), whereas the main intervention provided was patient counselling (41·0%). All problems were solved (98·5%) except for one because of the lack of cooperation of a patient. After 2 years, 36 participants (20%) were no longer persistent with therapy, 19 (10·6%) did not have clinic follow-up and 53 (26·8%) did not have a bone mineral density scan.


WHAT IS NEW AND CONCLUSION
The main PCIs identified were related to the use of bisphosphonates and its adverse effects. The study showed that the presence of a clinical pharmacist has enabled patients to voice their medication-related issues and to allow appropriate recommendations and actions to be taken to resolve these issues.
A phase I and pharmacokinetic study of intraperitoneal topotecan

Purpose: To evaluate the feasibility and pharmacology of intraperitoneal (IP) topotecan. Patients and methods: Fifteen patients with recurrent ovarian cancer in a phase I trial were treated with escalating IP topotecan doses (5–30 mg/m2) for pharmacokinetic analysis. Results: Dose limiting toxicity (DLT) was acute hypotension, chills and fever at the 30 mg/m2 dose level. Haematological toxicity and abdominal pain were mild for all dose levels studied. Pharmacokinetics: Peak plasma levels of total topotecan were reached at 2.7 ± 1.1 h after IP instillation. The apparent Vss was 69.9 ± 25.4 L/m2, plasma clearance 13.4 ± 2.5 L/h/m2 and plasma T1/2 3.7 ± 1.3 h. The plasma AUC was correlated with the dose (R = 0.95, P < 0.01). The plasma AUC ratio of lactone versus total topotecan (lactone + carboxy-forms) increased with the dose from 16% to 55%, (R = 0.84, P < 0.01). Peritoneal total topotecan was cleared from the peritoneal cavity at 0.4 ± 0.3 L/h.m2 with a T1/2 = 2.7 ± 1.7 h. The mean peritoneal/plasma AUC ratio for total topotecan was 54 ± 34. Conclusion: A substantial dose of topotecan can be delivered by the IP route, achieving cytotoxic plasma levels of topotecan, with acceptable toxicity. The recommended dose for further phase II trials is 20 mg/m2 IP, which enables combination with active doses of other cytotoxic drugs, in view of its limited myelotoxicity when given by this route. © 2001 Cancer Research Campaign http://www.bjcancer.com
pure sine wave inverter , 2 Implementation of SPWM in coding , 3 Circuit diagram for SPWM generation Modified sine wave inverter using pic microcontroller

In this work, a microcontroller based circuit that performs the functions of an inverter /AVR hardware essentially consists of a PIC 16F877A microcontroller based circuit,. SG 3524 based modified sine-wave inverter driver circuit, a step-up. Modified sine wave inverter is designed to using pic microcontroller and push pull topology. output of control circuit for modified sine wave inverter The micro controller based modify sine wave inverter is very good project which i will like. Find Freelance pic based sine wave inverter circuit Jobs. Hire experienced Freelance pic based sine wave inverter circuit professionals on Freelancer.com.
Collaborative Analysis of Cancer Patient Data using Rapid Miner

Breast cancer is one amongst the leading cancers for ladies in developed countries including Asian nation. It is the second most typical explanation for cancer death in women. The high incidence of breast cancer in women has redoubled considerably within the last years. In this paper discussion on varied data processing approaches that are used for carcinoma identification and prognosis. Carcinoma Diagnosis is identifying of benign from malignant breast lumps and carcinoma Prognosis predicts once Breast Cancer is to recur in patients that have had their cancers excised. This study paper summarizes various review and technical articles on carcinoma identification and prognosis additionally tend to concentrate on current analysis being dole out victimisation the info mining techniques to boost the breast cancer identification and prognosis.
Women, business and the law: measuring legal gender parity for entrepreneurs and workers

Purpose – Given the importance of legal parity between women and men in today's world and lack of research in this domain, the purpose of this paper is to identify gender‐based distinctions in formal laws and institutions that may directly or indirectly affect women's prospects as entrepreneurs and employees.Design/methodology/approach – Covering 128 economies, it establishes six indicators of gender differences in formal laws and institutions: accessing institutions; using property; getting a job; dealing with taxes; building credit; and going to court. The first three indicators capture laws that have direct gender dimensions and are based on a reading of such laws from the perspective of individual women. The fourth indicator examines the direct and indirect gender implications of tax policy from the perspective of four standardised families with varying tax liabilities. The last two indicators examine the ease of access to credit bureaus and courts to examine the indirect effects that microfinance ins...
A Novel Rapid DNA Microarray Assay Enables Identification of 37 Mycoplasma Species and Highlights Multiple Mycoplasma Infections

Mycoplasmas comprise a conglomerate of pathogens and commensals occurring in humans and animals. The genus Mycoplasma alone contains more than 120 species at present, and new members are continuously being discovered. Therefore, it seems promising to use a single highly parallel detection assay rather than develop separate tests for each individual species. In this study, we have designed a DNA microarray carrying 70 oligonucleotide probes derived from the 23S rRNA gene and 86 probes from the tuf gene target regions. Following a PCR amplification and biotinylation step, hybridization on the array was shown to specifically identify 31 Mycoplasma spp., as well as 3 Acholeplasma spp. and 3 Ureaplasma spp. Members of the Mycoplasma mycoides cluster can be recognized at subgroup level. This procedure enables parallel detection of Mollicutes spp. occurring in humans, animals or cell culture, from mono- and multiple infections, in a single run. The main advantages of the microarray assay include ease of operation, rapidity, high information content, and affordability. The new test's analytical sensitivity is equivalent to that of real-time PCR and allows examination of field samples without the need for culture. When 60 field samples from ruminants and birds previously analyzed by denaturing-gradient gel electrophoresis (DGGE) were tested by the microarray assay both tests identified the same agent in 98.3% of the cases. Notably, microarray testing revealed an unexpectedly high proportion (35%) of multiple mycoplasma infections, i.e., substantially more than DGGE (15%). Two of the samples were found to contain four different Mycoplasma spp. This phenomenon deserves more attention, particularly its implications for epidemiology and treatment.
Combining life cycle costing and life cycle assessment for an analysis of a new residential district energy system design

Due to the growing threat of climate change, we are challenged to find improved assessment practises to recognize solutions for sustainable urban development. The focus of the study is on the life cycle design of a district energy system for a new residential development in Finland. This study analyses LCC (life cycle costs) and carbon emissions (LCA (life cycle assessment)), i.e., the “viability” of different energy systems through a methodological life cycle framework. By combining LCC and LCA, a LCM (life cycle management) perspective is portrayed to support decision-making on a long-term basis. The comparable energy design options analysed are (1) district heating (reference design), (2) district heating with building integrated photovoltaic panels, (3) ground source heat pump, and (4) ground source heat pump with building-integrated photovoltaic panels. The results show that the design option with the highest initial investment (4) is in fact the most viable from a life cycle perspective. This study further strengthens the connection between cost savings and carbon emissions reduction in a life cycle context. Thus, by implementing LCC and LCA analysis in an early design phase, justified economic and environmental design decisions can be identified to develop more sustainable urban areas. 2013 The Authors. Published by Elsevier Ltd. Open access under CC BY license.
Amelioration of osteopenia and hypovitaminosis D by 1alpha-hydroxyvitamin D3 in elderly patients with Parkinson's disease.

OBJECTIVES
A high prevalence of hip and other fractures in elderly patients with Parkinson's disease has been linked to reduced bone mass arising from a defect of renal synthesis of 1, 25-dihydroxyvitamin D (1, 25-[OH]2D). Treatment with 1alpha-hydroxyvitamin D3 (1alpha(OH)D3; an active form of vitamin D) was evaluated for maintaining bone mass and reducing the incidence of hip and other nonvertebral fractures in patients with Parkinson's disease.


METHODS
In a double blind, randomised trial, 86 elderly patients with Parkinson's disease (mean Hoehn and Yahr stage, 3; mean age 70.6 years) were randomised to receive either 1 microg 1alpha(OH)D3 daily (treatment group, n=43) or a placebo (n=43) for 18 months. Bone mineral densities in the second metacarpals were determined by computed radiographic densitometry. Serum bone turnover indices were measured serially, and incidence of nonvertebral fractures was recorded.


RESULTS
Bone mineral densities decreased 1.2% in the treatment group compared with 6.7% in the placebo group during 18 months (p<0.0001). At baseline in both groups, the serum concentration of 1, 25-[OH]2D was reduced. Parathyroid hormone was abnormally increased in 15 patients (17%) and correlated negatively with serum 25-hydroxyvitamin D, indicating compensatory hyperparathyroidism. Eight patients sustained fractures (six at the hip and two at other sites) in the placebo group, and one hip fracture occurred among treated patients (odds ratio 9.8; p=0.0028).


CONCLUSION
By increasing serum 1, 25-[OH]2D concentrations, treatment with 1alpha(OH)D3 can reduce the risk of hip and other non-vertebral fractures in osteoporotic elderly patients with Parkinson's disease by slowing the loss of bone mineral densities.