LLukas22/scidocs huggingface dataset:
Deriving decision rules to locate export containers in container yards

A methodology is proposed to determine the storage location of an arriving export container considering its weight. We consider the con®guration of the container stack and the weight distribution of containers in the yard-bay. A dynamic programming model is formulated to determine the storage location to minimize the number of relocation movements expected for the loading operation. We also develop a decision tree from the set of the optimal solutions to support real time decisions. The performance of the decision tree is evaluated by the number of decisions that are dierent from the optimal solutions of the slower dynamic programming solution method. Ó 2000 Elsevier Science B.V. All rights reserved.
Genetic analysis of reaction time variability: room for improvement?

BACKGROUND
Increased reaction time variability (RTV) on cognitive tasks requiring a speeded response is characteristic of several psychiatric disorders. In attention deficit hyperactivity disorder (ADHD), the association with RTV is strong phenotypically and genetically, yet high RTV is not a stable impairment but shows ADHD-sensitive improvement under certain conditions, such as those with rewards. The state regulation theory proposed that the RTV difference score, which captures change from baseline to a rewarded or fast condition, specifically measures 'state regulation'. By contrast, the interpretation of RTV baseline (slow, unrewarded) scores is debated. We aimed to investigate directly the degree of phenotypic and etiological overlap between RTV baseline and RTV difference scores. Method We conducted genetic model fitting analyses on go/no-go and fast task RTV data, across task conditions manipulating rewards and event rate, from a population-based twin sample (n=1314) and an ADHD and control sibling-pair sample (n=1265).


RESULTS
Phenotypic and genetic/familial correlations were consistently high (0.72-0.98) between RTV baseline and difference scores, across tasks, manipulations and samples. By contrast, correlations were low between RTV in the manipulated condition and difference scores. A comparison across two different go/no-go task RTV difference scores (slow-fast/slow-incentive) showed high phenotypic and genetic/familial overlap (r = 0.75-0.83).


CONCLUSIONS
Our finding that RTV difference scores measure largely the same etiological process as RTV under baseline condition supports theories emphasizing the malleability of the observed high RTV. Given the statistical shortcomings of difference scores, we recommend the use of RTV baseline scores for most analyses, including genetic analyses.
Evaluating holistic needs assessment in outpatient cancer care—a randomised controlled trial: the study protocol

INTRODUCTION
People living with and beyond cancer are vulnerable to a number of physical, functional and psychological issues. Undertaking a holistic needs assessment (HNA) is one way to support a structured discussion of patients' needs within a clinical consultation. However, there is little evidence on how HNA impacts on the dynamics of the clinical consultation. This study aims to establish (1) how HNA affects the type of conversation that goes on during a clinical consultation and (2) how these putative changes impact on shared decision-making and self-efficacy.


METHODS AND ANALYSIS
The study is hosted by 10 outpatient oncology clinics in the West of Scotland and South West England. Participants are patients with a diagnosis of head and neck, breast, urological, gynaecological and colorectal cancer who have received treatment for their cancer. Patients are randomised to an intervention or control group. The control group entails standard care--routine consultation between the patient and clinician. In the intervention group, the patient completes a holistic needs assessment prior to consultation. The completed assessment is then given to the clinician where it informs a discussion based on the patient's needs and concerns as identified by them. The primary outcome measure is patient participation, as determined by dialogue ratio (DR) and preponderance of initiative (PI) within the consultation. The secondary outcome measures are shared decision-making and self-efficacy. It is hypothesised that HNA will be associated with greater patient participation within the consultation, and that shared decision-making and feelings of self-efficacy will increase as a function of the intervention.


ETHICS AND DISSEMINATION
This study has been given a favourable opinion by the West of Scotland Research Ethics Committee and NHS Research & Development. Study findings will be disseminated through peer-reviewed publications and conference attendance.


TRAIL REGISTRATION NUMBER
Clinical Trials.gov NCT02274701.
Gravitational interactions of integrable models

Abstract We couple non-linear σ-models to Liouville gravity, showing that integrability properties of symmetric space models still hold for the matter sector. Using similar arguments for the fermionic counterpart, namely Gross-Neveu-type models, we verify that such conclusions must also hold for them, as recently suggested.
Artificial Neural Network Optimization Modeling On Engine Performance Of Diesel Engine Using Biodiesel Fuel

This paper presents a study of engine performance using a mixture of palm oil methyl ester blends with diesel oil as biodiesel in a diesel engine, and optimizes the engine performance using artificial neural network (ANN) modeling. To acquire data for training and testing of the proposed ANN, a four-cylinder, four-stroke diesel engine was fuelled with different palm oil methyl ester blends as biodiesel, operated at different engine loads. The properties of biodiesel produced from waste vegetable oil were measured based on ASTM standards. The experimental results revealed that blends of palm oil methyl ester with diesel fuel provided better engine performance. An ANN model was developed based on the Levenberg-Marquardt algorithm for the engine. Logistic activation was used for mapping between the input and output parameters. It was observed that the ANN model could predict the engine performance quite well with correlation coefficients (R) of 0.996684, 0.999, 0.98964 and 0.998923 for the incylinder pressure, heat release, thermal efficiency, and volume, respectively. The predicted MSE (mean square error) error was between the desired outputs, as the measured and simulated values were obtained as 0.0001 by the model. Long-term effects on engine performance when running on biodiesel fuel can be further studied and improved.
Withdrawing performance indicators: retrospective analysis of general practice performance under UK Quality and Outcomes Framework

OBJECTIVES
To investigate the effect of withdrawing incentives on recorded quality of care, in the context of the UK Quality and Outcomes Framework pay for performance scheme.


DESIGN
Retrospective longitudinal study.


SETTING
Data for 644 general practices, from 2004/05 to 2011/12, extracted from the Clinical Practice Research Datalink.


PARTICIPANTS
All patients registered with any of the practices over the study period-13,772,992 in total.


INTERVENTION
Removal of financial incentives for aspects of care for patients with asthma, coronary heart disease, diabetes, stroke, and psychosis.


MAIN OUTCOME MEASURES
Performance on eight clinical quality indicators withdrawn from a national incentive scheme: influenza immunisation (asthma) and lithium treatment monitoring (psychosis), removed in April 2006; blood pressure monitoring (coronary heart disease, diabetes, stroke), cholesterol concentration monitoring (coronary heart disease, diabetes), and blood glucose monitoring (diabetes), removed in April 2011. Multilevel mixed effects multiple linear regression models were used to quantify the effect of incentive withdrawal.


RESULTS
Mean levels of performance were generally stable after the removal of the incentives, in both the short and long term. For the two indicators removed in April 2006, levels in 2011/12 were very close to 2005/06 levels, although a small but statistically significant drop was estimated for influenza immunisation. For five of the six indicators withdrawn from April 2011, no significant effect on performance was seen following removal and differences between predicted and observed scores were small. Performance on related outcome indicators retained in the scheme (such as blood pressure control) was generally unaffected.


CONCLUSIONS
Following the removal of incentives, levels of performance across a range of clinical activities generally remained stable. This indicates that health benefits from incentive schemes can potentially be increased by periodically replacing existing indicators with new indicators relating to alternative aspects of care. However, all aspects of care investigated remained indirectly or partly incentivised in other indicators, and further work is needed to assess the generalisability of the findings when incentives are fully withdrawn.
Modelling waving crops using large-eddy simulation: comparison with experiments and a linear stability analysis

HAL is a multi-disciplinary open access archive for the deposit and dissemination of scientific research documents, whether they are published or not. The documents may come from teaching and research institutions in France or abroad, or from public or private research centers. L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d’enseignement et de recherche français ou étrangers, des laboratoires publics ou privés. Modelling waving crops using large-eddy simulation: Comparison with experiments and a linear stability analysis S. Dupont, F. Gosselin, C. Py, Emmanuel De Langre, Pascal Hemon, Y. Brunet
Whole egg consumption improves lipoprotein profiles and insulin sensitivity to a greater extent than yolk-free egg substitute in individuals with metabolic syndrome.

OBJECTIVE
We investigated if daily egg feeding, along with carbohydrate restriction, would alter lipoprotein metabolism and influence atherogenic lipoprotein profiles and insulin resistance in men and women with metabolic syndrome (MetS).


METHODS
In a randomized, single-blind, parallel design, participants consumed either 3 whole eggs/day (EGG, n=20) or the equivalent amount of yolk-free egg substitute (SUB, n=17), as part of a moderately carbohydrate-restricted diet (25%-30% energy) for 12 weeks. Plasma lipids, apolipoproteins (apos), oxidized LDL (oxLDL), cholesteryl ester transfer protein (CETP) and lecithin-cholesterol acyltransferase (LCAT) activities were assessed at baseline and week 12. Lipoprotein particle concentrations and sizes were measured by nuclear magnetic resonance spectroscopy.


RESULTS
Atherogenic dyslipidemia improved for all individuals as evidenced by reductions in plasma triglycerides, apoC-III, apoE, oxLDL, VLDL particle diameter, large VDL, total IDL, small LDL, and medium LDL particles (P<0.05). Furthermore, there were increases in HDL-cholesterol, large LDL and large HDL particles (P<0.05) for all individuals. However, there were greater increases in HDL-cholesterol and large HDL particles, and reductions in total VLDL and medium VLDL particles for those consuming EGG compared to SUB (P<0.05). Plasma insulin and insulin resistance (HOMA-IR) were reduced, while LCAT activity, and both HDL and LDL diameters increased over time in the EGG group only (P<0.05).


CONCLUSIONS
Incorporating daily whole egg intake into a moderately carbohydrate-restricted diet provides further improvements in the atherogenic lipoprotein profile and in insulin resistance in individuals with MetS.
Effect of a High-Intensity Exercise Program on Physical Function and Mental Health in Nursing Home Residents with Dementia: An Assessor Blinded Randomized Controlled Trial

BACKGROUND
Dementia is among the leading causes of functional loss and disability in older adults. Research has demonstrated that nursing home patients without dementia can improve their function in activities of daily living, strength, balance and mental well being by physical exercise. The evidence on effect of physical exercise among nursing home patients with dementia is scarce and ambiguous. Thus, the primary objective of this study was to investigate the effect of a high intensity functional exercise program on the performance of balance in nursing home residents with dementia. The secondary objective was to examine the effect of this exercise on muscle strength, mobility, activities of daily living, quality of life and neuropsychiatric symptoms.


DESIGN AND METHODS
This single blinded randomized controlled trial was conducted among 170 persons with dementia living in nursing homes. Mean age was 86.7 years (SD = 7.4) and 74% were women. The participants were randomly allocated to an intervention (n = 87) or a control group (n = 83). The intervention consisted of intensive strengthening and balance exercises in small groups twice a week for 12 weeks. The control condition was leisure activities.


RESULTS
The intervention group improved the score on Bergs Balance Scale by 2.9 points, which was significantly more than the control group who improved by 1.2 points (p = 0.02). Having exercised 12 times or more was significantly associated with improved strength after intervention (p<0.05). The level of apathy was lower in the exercise group after the intervention, compared to the control group (p = 0.048).


CONCLUSION
The results from our study indicate that a high intensity functional exercise program improved balance and muscle strength as well as reduced apathy in nursing home patients with dementia.


TRIAL REGISTRATION
ClinicalTrials.gov NCT02262104.
Shared decision making for prostate cancer screening: the results of a combined analysis of two practice-based randomized controlled trials

BACKGROUND
Professional societies recommend shared decision making (SDM) for prostate cancer screening, however, most efforts have promoted informed rather than shared decision making. The objective of this study is to 1) examine the effects of a prostate cancer screening intervention to promote SDM and 2) determine whether framing prostate information in the context of other clearly beneficial men's health services affects decisions.


METHODS
We conducted two separate randomized controlled trials of the same prostate cancer intervention (with or without additional information on more clearly beneficial men's health services). For each trial, we enrolled a convenience sample of 2 internal medicine practices, and their interested physicians and male patients with no prior history of prostate cancer (for a total of 4 practices, 28 physicians, and 128 men across trials). Within each practice site, we randomized men to either 1) a video-based decision aid and researcher-led coaching session or 2) a highway safety video. Physicians at each site received a 1-hour educational session on prostate cancer and SDM. To assess intervention effects, we measured key components of SDM, intent to be screened, and actual screening. After finding that results did not vary by trial, we combined data across sites, adjusting for the random effects of both practice and physician.


RESULTS
Compared to an attention control, our prostate cancer screening intervention increased men's perceptions that screening is a decision (absolute difference +41%; 95% CI 25 to 57%) and men's knowledge about prostate cancer screening (absolute difference +34%; 95% CI 19% to 50%), but had no effect on men's self-reported participation in shared decisions or their participation at their preferred level. Overall, the intervention decreased screening intent (absolute difference -34%; 95% CI -50% to -18%) and actual screening rates (absolute difference -22%; 95% CI -38 to -7%) with no difference in effect by frame.


CONCLUSIONS
SDM interventions can increase men's knowledge, alter their perceptions of prostate cancer screening, and reduce actual screening. However, they may not guarantee an increase in shared decisions.


TRIAL REGISTRATION
#NCT00630188.
The Design Hints of Science and Education Building in Middle School

Through the design process of science and education building of the fourth middle school in Zhuzhou city, this paper introduces the total plane layout function processing, modeling and detail structure and interior design.
Multi-crop Convolutional Neural Networks for lung nodule malignancy suspiciousness classification

We investigate the problem of lung nodule malignancy suspiciousness (the likelihood of nodule malignancy) classification using thoracic Computed Tomography (CT) images. Unlike traditional studies primarily relying on cautious nodule segmentation and time-consuming feature extraction, we tackle a more challenging task on directly modeling raw nodule patches and building an end-to-end machinelearning architecture for classifying lung nodule malignancy suspiciousness. We present a Multi-crop Convolutional Neural Network (MC-CNN) to automatically extract nodule salient information by employing a novel multi-crop pooling strategy which crops different regions from convolutional feature maps and then applies max-pooling different times. Extensive experimental results show that the proposed method not only achieves state-of-the-art nodule suspiciousness classification performance, but also effectively characterizes nodule semantic attributes (subtlety and margin) and nodule diameter which are potentially helpful in modeling nodule malignancy. & 2016 Elsevier Ltd. All rights reserved.
Switching to biphasic insulin aspart 30/50/70 from biphasic human insulin 30/50 in patients with type 2 diabetes in normal clinical practice: observational study results.

OBJECTIVE
To investigate the safety and efficacy of switching to biphasic insulin aspart (BIAsp) 30, 50 or 70 in patients with type 2 diabetes previously treated with biphasic human insulin (BHI) 30/50 (with or without oral glucose-lowering drugs) in routine clinical practice.


METHODS
This was a 26-week, prospective, observational study conducted in Belgium and Luxembourg. Data were collected at baseline before patients switched and at 12 and 26 weeks after starting BIAsp 30, 50 or 70. Safety endpoints were incidence and rate of hypoglycemia (major, minor, nocturnal), adverse events and body-weight changes. Efficacy assessments included HbA(1c) and 7-point self-measured plasma glucose (PG) profiles. Changes from baseline were analyzed using paired t-tests.


RESULTS
Of 592 patients analyzed, 72% switched to twice-daily BIAsp and 20% to three-times daily BIAsp. Upon switching, 27% of patients received intensified treatment (i.e., more daily doses than with their previous BHI). At all three data-collection points, approximately two-thirds of patients were taking BIAsp 30 and approximately one-third were taking BIAsp 50; very few patients took BIAsp 70. Mean total daily insulin dose increased significantly from baseline (51.2 U) to 26 weeks (54.3 U) and mean time of intake before meals changed from 17 minutes for BHI to ∼3 minutes with BIAsp. Incidence of hypoglycemia did not change during the study (baseline: 30.7%, week 26: 29.2%). HbA(1c) improved significantly from baseline (7.9 %) to weeks 12 and 26 (7.6% and 7.5%, respectively; p < 0.001). Mean PG profiles also showed significant improvements. As this is an observational study, some limitations should be considered such as the absence of a control group and a possible bias of increased medical attention.


CONCLUSIONS
Patients with long-standing type 2 diabetes can switch safely from BHI to BIAsp therapy, even if they receive intensified treatment, and they have no problems changing the timing of their insulin injections.
Accessing educational approaches to Building Information Modeling (BIM) at construction management master studies in Croatia

Preliminary communication Building Information Modelling (BIM) is the current trend of the Architectural, Engineering and Construction (AEC) industry today. For its successful adaptation, education and standardization are one of the key success factors. In education, BIM provides development of students’ critical way of thinking and enables them to understand the complexity of the construction industry. As there is no accurate information about BIM education at Croatian universities, the aim of this paper was its implementation at the University J. J. Strossmayer of Osijek and the University of Zagreb. We have found that the current schemes enabled students to understand the BIM concept and how BIM changes and fosters the work processes in construction projects. However, we have also identified the deficient knowledge in coordination, interoperability and clash detection. Therefore, the future work involves extension on collaboration tools and covering the above mentioned, missing knowledge areas.
The Logic Programming Paradigm and Prolog

This is a tutorial on logic programming and Prolog appropriate for a course on programming languages for students familiar with imperative programming.
Functional analysis of cases of tumor endoprostheses with deep infection around the knee: a multi institutional study by the Japanese Musculoskeletal Oncology Group (JMOG).

BACKGROUND
Although intensive studies have been conducted to clarify the incidence, risks, and management methods of deep infection of tumor endoprostheses, limited data have been published in respect of the impact of such deep infection on the function of the corresponding limb.


METHODS
Clinical data of 125 patients (infection group 57, control group 68) with malignant bone and soft tissue tumors around the knee enrolled with the Japanese Musculoskeletal Oncology Group were collected. We analyzed the impact of deep infection of tumor endoprostheses on the limb salvage status together with that on the function of the salvaged limb. The definition of deep infection was based on the recommendations of the Centers for Disease Control and Prevention. The functional evaluation was based on the functional classification system established by the International Society of Limb Salvage and the Musculoskeletal Tumor Society.


RESULTS
Infection together with extracapsular resection was demonstrated to be a risk factor for late amputation. There were no significant differences in the functional scores for "pain," "support," "walking," or "gait" between the infection and control groups. The risk factors identified for a loss of score for "functional activities" were deep infection, age, duration of operation, and extracapsular resection. The infection group also showed a significant lower score loss in "emotion". As for the overall functional scores, the risk factors identified for lower scores were deep infection and age. The mean scores for the infection group and control group were 19.3 (64.3 %) and 21.6 (72 %), respectively. Although the difference was confirmed to be statistically significant, the actual difference was only 2.3 (10.6 % reduction).


CONCLUSIONS
Infection was a major risk factor for late amputation. Limbs salvaged by management of deep infection may show loss of function; however, the impact may be limited.