LLukas22/scidocs huggingface dataset:
Protocol for the Cognitive Interventions and Nutritional Supplements (CINS) trial: A randomized controlled multicenter trial of a brief intervention (BI) versus a BI plus cognitive behavioral treatment (CBT) versus nutritional supplements for patients with long-lasting muscle and back pain

BACKGROUND
Brief intervention programs are clinically beneficial, and cost efficient treatments for low back pain, when offered at 8-12 weeks, compared with treatment as usual. However, about 30% of the patients do not return to work. The European Guidelines for treatment of chronic low back pain recommends Cognitive Behavioral Therapy (CBT), but conclude that further research is needed to evaluate the effectiveness of CBT for chronic low back pain.


METHODS/DESIGN
The aim of the multicenter CINS trial (Cognitive Interventions and Nutritional Supplements) is to compare the effectiveness of 4 different interventions; Brief Intervention, Brief Intervention and CBT, Brief Intervention and nutritional supplements of seal oil, and Brief Intervention and nutritional supplements of soy oil. All participants will be randomly assigned to the interventions. The nutritional supplements will be tested in a double blind design. 400 patients will be recruited from a population of chronic low back pain patients that have been sick listed for 2-10 months. Four outpatient clinics, located in different parts of Norway, will participate in recruitment and treatment of the patients.The Brief Intervention is a one session cognitive, clinical examination program based on a non-injury model, where return to normal activity and work is the main goal, and is followed by two booster sessions. The CBT is a tailored treatment involving 7 sessions, following a detailed manual. The nutritional supplements consist of a dosage of 10 grams of either soy or seal oil (capsules) per day for 3 months, administered in a double blind design. All patients will be followed up with questionnaires after 3, 6 and 12 months, while sick leave data will be collected up to at least 24 months after randomization. The primary outcome of the study is sick leave and will be based on register data from the National Insurance Administration. Secondary outcomes include self-reported data on disability, pain, and psychological variables.


CONCLUSIONS
To our knowledge, the CINS trial will be the largest, randomized trial of psychological and nutritional interventions for chronic low back pain patients to date. It will provide important information regarding the effectiveness of CBT and seal oil for chronic low back pain patients.


TRIAL REGISTRATION
http://www.clinicaltrials.gov, with registration number NCT00463970.
Modeling population density using land cover data

This study investigates the correlation between land cover data and other factors that affect population distribution. The results show that land cover data contain sufficient information to infer population distribution and can be used independently to model the spatial pattern of population density in China. China’s population distribution model (CPDM) was developed based on land cover data to calculate population density in China at 1 km resolution. For cells in rural areas, population probability coefficients were calculated based on weighted linear models, the weights of land cover types being derived from multivariate regression models and on a qualitative order of land types in 12 agro-ecological zones. For cells in urban areas, a power exponential decay model based on city size and the distance from urban center was employed to calculate population probability coefficients. The models were validated in sampled cells using ancillary population data. The validation shows the mean relative error of estimated f CPDM is
Decoding-History-Based Adaptive Control of Attention for Neural Machine Translation

Attention-based sequence-to-sequence model has proved successful in Neural Machine Translation (NMT). However, the attention without consideration of decoding history, which includes the past information in the decoder and the attention mechanism, often causes much repetition. To address this problem, we propose the decoding-history-based Adaptive Control of Attention (ACA) for the NMT model. ACA learns to control the attention by keeping track of the decoding history and the current information with a memory vector, so that the model can take the translated contents and the current information into consideration. Experiments on Chinese-English translation and the EnglishVietnamese translation have demonstrated that our model significantly outperforms the strong baselines. The analysis shows that our model is capable of generating translation with less repetition and higher accuracy. The code will be available at https://github.com/lancopku
Sustainable intensification in agricultural systems.

BACKGROUND
Agricultural systems are amended ecosystems with a variety of properties. Modern agroecosystems have tended towards high through-flow systems, with energy supplied by fossil fuels directed out of the system (either deliberately for harvests or accidentally through side effects). In the coming decades, resource constraints over water, soil, biodiversity and land will affect agricultural systems. Sustainable agroecosystems are those tending to have a positive impact on natural, social and human capital, while unsustainable systems feed back to deplete these assets, leaving fewer for the future. Sustainable intensification (SI) is defined as a process or system where agricultural yields are increased without adverse environmental impact and without the conversion of additional non-agricultural land. The concept does not articulate or privilege any particular vision or method of agricultural production. Rather, it emphasizes ends rather than means, and does not pre-determine technologies, species mix or particular design components. The combination of the terms 'sustainable' and 'intensification' is an attempt to indicate that desirable outcomes around both more food and improved environmental goods and services could be achieved by a variety of means. Nonetheless, it remains controversial to some.


SCOPE AND CONCLUSIONS
This review analyses recent evidence of the impacts of SI in both developing and industrialized countries, and demonstrates that both yield and natural capital dividends can occur. The review begins with analysis of the emergence of combined agricultural-environmental systems, the environmental and social outcomes of recent agricultural revolutions, and analyses the challenges for food production this century as populations grow and consumption patterns change. Emergent criticisms are highlighted, and the positive impacts of SI on food outputs and renewable capital assets detailed. It concludes with observations on policies and incentives necessary for the wider adoption of SI, and indicates how SI could both promote transitions towards greener economies as well as benefit from progress in other sectors.
Improving state-of-the-art OCR through high-precision document-specific modeling

Optical character recognition (OCR) remains a difficult problem for noisy documents or documents not scanned at high resolution. Many current approaches rely on stored font models that are vulnerable to cases in which the document is noisy or is written in a font dissimilar to the stored fonts. We address these problems by learning character models directly from the document itself, rather than using pre-stored font models. This method has had some success in the past, but we are able to achieve substantial improvement in error reduction through a novel method for creating nearly error-free document-specific training data and building character appearance models from this data. In particular, we first use the state-of-the-art OCR system Tesseract to produce an initial translation. Then, our method identifies a subset of words that we have high confidence have been recognized correctly and uses this subset to bootstrap document-specific character models. We present theoretical justification that a word in the selected subset is very unlikely to be incorrectly recognized, and empirical results on a data set of difficult historical newspaper scans demonstrating that we make only two errors in 56 documents. We then relax the theoretical constraint in order to create a larger training set, and using document-specific character models generated from this data, we are able to reduce the error over properly segmented characters by 34.1% overall from the initial Tesseract translation.
Immunohistochemical profiling of Wilms tumor: a tissue microarray study.

AIM
Wilms tumor (WT) usually shows a bi-phasic or tri-phasic morphology comprised of blastemal, stromal, and epithelial cells. Other biphasic renal tumors that can mimic WT may pose diagnostic dilemmas especially in preoperative needle biopsy samples. This tissue microarray study was designed to investigate the immunohistochemical features that may prove useful in the accurate diagnosis of WT in small biopsy samples.


METHODS
Eight punches from each paraffin block of 45 cases of WTs were used to construct 5 tissue microarray blocks. Immunohistochemical reactions of blastemal, stromal, and epithelial cells of each core to a panel of 37 antibodies were evaluated.


RESULTS
Blastemal elements expressed CD56 (22, 57%), CD57 (19, 55%), cytokeratin 22 (CK22) (12, 27%), and CK8 (9, 21%). Epithelial cells were stained mostly with CK22 (17, 94%), CK18 (12, 66%), CK8 (14, 70%), CD57 (10, 76%), CD56 (6, 43%), EMA (7, 44%), and CK19 (5, 25%). Stromal cells expressed SMA (21, 50%), actin (18, 48%), desmin (9, 20%), CD34 (7, 24%), CD57 (5, 18%), and CD56 (5, 15%). Only one case was positive for CK5/6, CK13, CK14, and CK20. Calretinin expression was seen in the stromal cells of 3 and placental alkaline phosphatase expression was observed in 1 case. All 3 components were negative for CK1, CK7, myoglobin, Myf-4, MyoD1, HMB45, chromogranin A, synaptophysin, Melan A, beta-HCG, alpha-HCG, alpha-Inhibin, renal cell carcinoma antigen, glycophorin A, PSA, and estrogen and progesterone receptors.


CONCLUSIONS
CD56, CD57, CK22, CK18, CK8, EMA, SMA, and actin are useful markers for an accurate diagnosis of WT in small biopsy samples.
Why Haven't We Mastered Alignment? The Importance of the Informal Organization Structure

1 This article was reviewed and accepted by all the senior editors, including the editor-in-chief. Articles published in future issues will be accepted by just a single senior editor, based on reviews by members of the Editorial Board. 2 Sincere thanks go to Anna Dekker and Denyse O’Leary for their assistance with this research. Funding was generously provided by the Advanced Practices Council of the Society for Information Management and by the Social Sciences and Humanities Research Council of Canada. An earlier version of this manuscript was presented at the Academy of Management Conference in Toronto, Canada, in August 2000. 3 In this article, the terms information systems (IS) and information technology (IT) are used interchangeably. 4 Regardless of whether IS services are provided internally (in a centralized, decentralized, or federal manner) or are outsourced, we assume the boundaries of the IS function can be identified. Thus, the fit between the unit(s) providing IS services and the rest of the organization can be examined. and books have been written on the subject, firms continue to demonstrate limited alignment.
No Silver Bullet Essence and Accidents of Software Engineering

But, as we look to the horizon of a decade hence, we see no silver bullet. There is no single development, in either technology or in management technique, that by itself promises even one orderof-magnitude improvement in productivity, in reliability, in simplicity. In this article, I shall try to show why, by examining both the nature of the software problem and the properties of the bullets proposed.
An Overview of Near Field UHF RFID

In this paper, an overview of near field UHF RFID is presented. This technology recently received attention because of its possible use for item-level tagging where LF/HF RFID has traditionally been used. We review the relevant literature, discuss basic theory of near and far field antenna coupling in application to RFID, and present some experimental measurements.
Glucosamine sulfate reduces osteoarthritis progression in postmenopausal women with knee osteoarthritis: evidence from two 3-year studies.

OBJECTIVE
To investigate the effect of glucosamine sulfate on long-term symptoms and structure progression in postmenopausal women with knee osteoarthritis (OA).


DESIGN
This study consisted of a preplanned combination of two three-year, randomized, placebo-controlled, prospective, independent studies evaluating the effect of glucosamine sulfate on symptoms and structure modification in OA and post-hoc analysis of the results obtained in postmenopausal women with knee OA. Minimal joint space width was assessed at baseline and after 3 years from standing anteroposterior knee radiographs. Symptoms were scored by the algo-functional WOMAC index at baseline and after 3 years. All primary statistical analyses were performed in intention-to-treat, comparing joint space width and WOMAC changes between groups by ANOVA.


RESULTS
Of 414 participants randomized in the two studies, 319 were postmenopausal women. At baseline, glucosamine sulfate and placebo groups were comparable for demographic and disease characteristics, both in the general population and in the postmenopausal women subset. After 3 years, postmenopausal participants in the glucosamine sulfate group showed no joint space narrowing [joint space change of +0.003 mm (95% CI, -0.09 to 0.11)], whereas participants in the placebo group experienced a narrowing of -0.33 mm (95% CI, -0.44 to -0.22; P < 0.0001 between the two groups). Percent changes after 3 years in the WOMAC index showed an improvement in the glucosamine sulfate group [-14.1% (95%, -22.2 to -5.9)] and a trend for worsening in the placebo group (5.4% (95% CI, -4.9 to 15.7) (P = 0.003 between the two groups).


CONCLUSION
This analysis, focusing on a large cohort of postmenopausal women, demonstrated for the first time that a pharmacological intervention for OA has a disease-modifying effect in this particular population, the most frequently affected by knee OA.
How urban structure can affect city sustainability from an air quality perspective

Despite the progress made in controlling local air pollution, urban areas show increasing signs of environmental stress and air quality is one of the major concerns. The findings of several studies provide evidence that the shape of a city and the land use distribution determine the location of emission sources and the pattern of urban traffic, affecting urban air quality. This work focuses on the potential impacts of different land use patterns on urban air quality. Three imaginary cities were created, based on alternative urban planning strategies, considering different land use patterns: from the scenario of urban sprawl to the opposite scenario of a compact city with mixed land use. The mesoscale photochemical system MEMO/MARS was applied to evaluate the urban air quality in each of the idealized city structures. Simulation results indicate that more compact cities with mixed land use provide better urban air quality compared to disperse and network cities. 2005 Elsevier Ltd. All rights reserved.
The Critical Role of Knowledge Management in Achieving and Sustaining Organisational Competitive Advantage

The critical role of knowledge management in achieving and sustaining competitive advantage has been strongly emphasised in the extant literature. However, most previous studies were conceptually grounded and empirically examined in advanced, developed and newly industrialised countries. In addition, research to date has predominantly explored findings from a large company view while little attempt has been made to address the relative importance of different factors constituting the organisational KM capability in the context of Asian emerging, less developed countries such as Vietnam where a socialist market economy, a Confucian culture and a majority of small and medium sized enterprises currently exist. By adopting a resource-based theory of the firm with an extension of a knowledge-based perspective, this paper aims at developing and empirically validating a conceptual model of the relationships between KM capability components and their impacts on a firm’s competitive advantage in Vietnam. The results of 148 surveyed respondents in the construction industry reconfirmed a general agreement found in the literature that a combined social and technological approach is ideal to take advantage of their significant positive correlations in improving organisational competitive advantage. Moreover, in the Vietnamese-specific context, the study indicated that while culture is the most important issue affecting knowledge management, integration with information technology may assist to overcome cultural barriers and provide a stronger contribution to competitive advantage.
Kant and the Priority of Self-Knowledge

In The Metaphysics of Morals, Kant claims that “the first command” of all self-regarding duties is to know our “heart.” Kant ostensibly identifies our heart with our moral disposition. Strangely, this appears to be precisely the sort of knowledge that, elsewhere, Kant claims is epistemically inaccessible to us. While the more sophisticated attempts to resolve this difficulty succeed in situating an injunction to know the quality of one’s disposition within a Kantian epistemic framework, no account is wholly successful in explaining why Kant takes self-knowledge to be a necessary condition of virtue. To make sense of the priority Kant assigns to the pursuit of selfknowledge, I argue that it is essential to understand the role of what has been called “generic” self-knowledge in Kant’s moral philosophy. I proceed to defend the place Kant grants moral selfknowledge in his moral philosophy, primarily by developing a Kantian account of such “generic” self-knowledge. INDEX WORDS: Kant, Self-knowledge, Virtue KANT AND THE PRIORITY OF SELF-KNOWLEDGE
Feasibility of a mindfulness-based stress reduction program for early-stage breast cancer survivors.

PURPOSE
To assess the feasibility of whether mindfulness-based stress reduction (MBSR) has a positive effect on breast cancer survivors' psychological status, psychosocial characteristics, symptoms, and quality of life (QOL) during the critical transition period from end of treatment to resumption of daily activities.


DESIGN
Single-group, quasi-experimental, pretest-posttest design.


METHOD
A sample of 19 women who completed breast cancer treatment with lumpectomy, radiation, and/or chemotherapy was recruited from the Moffitt Cancer Center and Research Institute, a National Cancer Institute- designated cancer center, and the University of South Florida. The authors assessed the feasibility, compliance, and whether an 8-week MBSR program positively influenced changes in psychological status (fear of recurrence, perceived stress, anxiety, depression), psychosocial characteristics (optimism, social support, spirituality), physical symptoms, and QOL.


FINDINGS
Seventeen women (89.5%) completed the study. The mean age was 57 years; the majority of participants (94%) were White. The estimated compliance rate for the program was 67%. Paired t tests indicated significant improvements fear of recurrence, perceived stress, anxiety, depression, and QOL through MBSR participation.


CONCLUSIONS
Participants enrolled in the MBSR classes generally were compliant. Significant improvement in psychological status, symptoms, and QOL can be achieved with MBSR use in this population.
Effect of σ(600)-production in pp → 3π0 at rest

Abstract The π 0 π 0 mass spectra and angular distributions around K K - threshold and at 1.5 GeV in p p (at rest) → 3π 0 in the Crystal Barrel experiment are reanalyzed by applying the new method, which is consistent with unitarity of S -matrix and expressed directly by resonance parameters. The effects of light σ-meson production are clearly seen to improve the fit with σ, in comparing with the fit without σ.
Acute effects of intravenous cocaine on pulmonary artery pressure and cardiac index in habitual crack smokers.

BACKGROUND
Some habitual crack cocaine smokers who deny IV drug abuse show decreased pulmonary transfer of carbon monoxide (DCO). We speculated that repeated elevations in pulmonary artery pressure (PAP) might cause pulmonary capillary damage and result in a lowered DCO, or that the reduction could be due to anoxic lung injury secondary to repeated episodes of cocaine-induced pulmonary vascular constriction.


STUDY OBJECTIVE
Compare the acute effects of i.v. cocaine HCl and placebo on PAP, cardiac stroke volume, and cardiac output estimated indirectly by continuous Doppler echocardiography.


DESIGN
A single-blind crossover study in which placebo always preceded the active drug.


SUBJECTS
Ten current crack-smoking subjects, 32 to 47 years of age, with a history of limited previous i.v. cocaine use.


METHODS
PAP, cardiac stroke volume, heart rate, and BP were measured continuously after injection of placebo followed by cocaine HCl (0.5 mg/kg).


RESULTS
i.v. cocaine resulted in no significant change in PAP (-0.14 +/- 3.3[SD] mm Hg, 95% confidence interval [CI] for difference -2.48, +2.21). Stroke volume index showed no significant change after cocaine (-0.1 +/- 2.0 mL; 95% CI, -1.5, +1.3). Heart rate showed a significant increase (10.0 +/- 7.2 min-1; p = 0.0017, 95% CI, +4.9, +15.1). Cardiac index showed a significant increase (0.48 +/- 0.32 L/min; p = 0.0012, 95% CI, +0.25, +0.71). Pulmonary vascular resistance showed no significant change (-44 +/- 101 dyne.s.cm-5/m2, 95% CI, -116, +29).


CONCLUSIONS
i.v. cocaine HCl does not cause short-term increases in PAP or stroke volume index, but causes an increase in cardiac index due to its chronotropic effect.
Questioning Answering By Pattern Matching, Web-Proofing, Semantic Form Proofing

In this paper, we introduce the University at Albany’s question answering system, ILQUA. It is developed on the following methods: pattern matching over annotated text, web-proofing and semantic form proofing. These methods are currently used in other QA systems, however, we revised them to work together in our QA system.
Efficient production of l-lactic acid using co-feeding strategy based on cane molasses/glucose carbon sources.

L-Lactic acid is an important platform chemical, which ought to be produced under cost control to meet its huge demand. Cane molasses, a waste from sugar manufacturing processes, is hopeful to be utilized as a cheap carbon source for L-lactic acid fermentation. Considering that cane molasses contains nutrients and hazardous substances, efficient production of L-lactic acid was developed by using a co-feeding strategy based on the utilization of cane molasses/glucose carbon sources. Based on the medium optimization with response surface method, 168.3g/L L-lactic acid was obtained by a Bacillus coagulans strain H-1 after 78h fed-batch fermentation, with a productivity of 2.1g/Lh and a yield of 0.88g/g. Since cane molasses is a feasible carbon source, the co-feeding fermentation might be a promising alternative for the economical production of L-lactic acid.
Detecting harmful gases using fluctuation-enhanced sensing with Taguchi sensors

Sensing techniques are often required to not only be versatile and portable, but also to be able to enhance sensor information. This paper describes and demonstrates a new approach to chemical signal analysis that we call fluctuation-enhanced sensing. It utilizes the entire bandwidth of the sensor signal in contrast to more conventional approaches that rely on the dc response. The new principle holds prospects for significantly reducing the necessary number of sensors in artificial noses and tongues, and it can provide improved sensitivity.