LLukas22/scidocs huggingface dataset:
Analysis of quality of life among asthmatic individuals with obesity and its relationship with pulmonary function: cross-sectional study.

CONTEXT AND OBJECTIVE:
The combined effect of obesity and asthma may lead to significant impairment of quality of life (QOL). The aim here was to evaluate the prevalence of asthma among obese individuals, characterize the severity of impairment of quality of life and measure its relationship with pulmonary function.


DESIGN AND SETTING:
Observational cross-sectional study in public university hospital.


METHODS:
Morbidly obese individuals (body mass index > 40 kg/m2) seen in a bariatric surgery outpatient clinic and diagnosed with asthma, were included. Anthropometric data were collected, the Standardized Asthma Quality of Life Questionnaire (AQLQ(S)) was applied and spirometry was performed. The subjects were divided into two groups based on the median of the score in the questionnaire (worse < 4 and better > 4) and were compared regarding anthropometric data and pulmonary function.


RESULTS:
Among the 4791 individuals evaluated, 219 were asthmatic; the prevalence of asthma was 4.57%. Of these, 91 individuals were called to start multidisciplinary follow-up during the study period, of whom 82 answered the questionnaire. The median score in the AQLQ(S) was 3.96 points and, thus, the individuals were classified as having moderate impairment of their overall QOL. When divided according to better or worse QOL, there was a statistically difference in forced expiratory flow (FEF) 25-75%, with higher values in the better QOL group.


CONCLUSION:
The prevalence of asthma was 4.57% and QOL was impaired among the asthmatic obese individuals. The worst QOL domain related to environmental stimuli and the best QOL domain to limitations of the activities. Worse QOL was correlated with poorer values for FEF 25-75%.
Validation of sub-segmental visual scoring for the quantification of ischemic and nonischemic myocardial fibrosis using late gadolinium enhancement MRI.

PURPOSE
To determine the accuracy and reproducibility of late gadolinium enhancement (LGE) MRI scar quantification using visual sub-segmental analysis (VSSA) versus signal threshold-based analysis in ischemic and nonischemic cardiomyopathy.


MATERIALS AND METHODS
One-hundred sixty-one patients with abnormal LGE imaging underwent VSSA and signal threshold-based analysis. VSSA was performed using a 68 sub-segmental model. Signal threshold-based analysis was performed using cutoffs of ≥2, ≥3, and ≥5 standard deviations (SD) above the mean signal of normal myocardium. Comparison of VSSA and signal threshold-based analysis was performed by linear regression and Bland Altman plots.


RESULTS
Seventy (44%) patients had ischemic scar, 76 (47%) had nonischemic scar, and 15 (9%) had a combined pattern. Correlation coefficients for VSSA versus signal threshold-based analysis at ≥2, ≥3, and ≥5SD thresholds were r = 0.63, r = 0.79, r = 0.81 (P < 0.001) for all patients, r = 0.74, r = 0.81, r = 0.81 (P < 0.001) in those with ischemic scar, and r = 0.46, r = 0.69, r = 0.72 (P < 0.001) in those with nonischemic scar. Bland Altman analysis revealed no significant bias in total scar volume among all patients (-4.3 ± 7.9%), those with ischemic scar (-4.8 ± 7.8%), or those with nonischemic scar (-2.6 ± 7.6%). Intra-observer and inter-observer variability of the VSSA technique was excellent with a mean difference in total percent scar of 0.3% (-8.3-8.9%) and -0.4% (-9.5-8.5%), respectively.


CONCLUSION
A VSSA-based model of myocardial scar quantification is accurate and reproducible in ischemic and nonischemic cardiomyopathy.
Duplication of lower lip and mandible--a rare diprosopus.

Diprosopus or duplication of the lower lip and mandible is a very rare congenital anomaly. We report this unusual case occurring in a girl who presented to our hospital at the age of 4 months. Surgery and problems related to this anomaly are discussed.
Effectiveness and cost of a transitional care program for heart failure: a prospective study with concurrent controls.

BACKGROUND
Randomized controlled trials have demonstrated the efficacy of nurse-led transitional care programs to reduce readmission rates for patients with heart failure; the effectiveness of these programs in real-world health care systems is less well understood.


METHODS
We performed a prospective study with concurrent controls to test an advanced practice nurse-led transitional care program for patients with heart failure who were 65 years or older and were discharged from Baylor Medical Center Garland (BMCG) from August 24, 2009, through April 30, 2010. We compared the effect of the program on 30-day (from discharge) all-cause readmission rate, length of stay, and 60-day (from admission) direct cost for BMCG with that of other hospitals within the Baylor Health Care System. We also performed a budget impact analysis using costs and reimbursement experience from the intervention.


RESULTS
The intervention significantly reduced adjusted 30-day readmission rates to BMCG by 48% during the postintervention period, which was better than the secular reductions seen at all other facilities in the system. The intervention had little effect on length of stay or total 60-day direct costs for BMCG. Under the current payment system, the intervention reduced the hospital financial contribution margin on average $227 for each Medicare patient with heart failure.


CONCLUSIONS
Preliminary results suggest that transitional care programs reduce 30-day readmission rates for patients with heart failure. This underscores the potential of the intervention to be effective in a real-world setting, but payment reform may be required for the intervention to be financially sustainable by hospitals.
Wireless VR/AR with Edge/Cloud Computing

Triggered by several head-mounted display (HMD) devices that have come to the market recently, such as Oculus Rift, HTC Vive, and Samsung Gear VR, significant interest has developed in virtual reality (VR) systems, experiences and applications. However, the current HMD devices are still very heavy and large, negatively affecting user experience. Moreover, current VR approaches perform rendering locally either on a mobile device tethered to an HMD, or on a computer/console tethered to the HMD. In this paper, we discuss how to enable a truly portable and mobile VR experience, with light weight VR glasses wirelessly connecting with edge/cloud computing devices that perform the rendering remotely. We investigate the challenges associated with enabling the new wireless VR approach with edge/cloud computing with different application scenarios that we implement. Specifically, we analyze the challenging bitrate and latency requirements to enable wireless VR, and investigate several possible solutions.
Automated breast cancer detection and classification using ultrasound images: A survey

Article history: Received 9 September 2008 Received in revised form 16 April 2009 Accepted 14 May 2009
Potential Formula for the Calculation of Starting and Incremental Insulin Glargine Doses: ALOHA Subanalysis

BACKGROUND
Pragmatic methods for dose optimization are required for the successful basal management in daily clinical practice. To derive a useful formula for calculating recommended glargine doses, we analyzed data from the Add-on Lantus® to Oral Hypoglycemic Agents (ALOHA) study, a 24-week observation of Japanese type 2 diabetes patients.


METHODOLOGY/PRINCIPAL FINDINGS
The patients who initiated insulin glargine in basal-supported oral therapy (BOT) regimen (n = 3506) were analyzed. The correlations between average changes in glargine dose and HbA1c were calculated, and its regression formula was estimated from grouped data categorized by baseline HbA1c levels. Starting doses of the background-subgroup achieving the HbA1c target with a last-observed dose above the average were compared to an assumed optimal starting dose of 0.15 U/kg/day. The difference in regression lines between background-subgroups was examined. A formula for determining the optimal starting and titration doses was thereby derived. The correlation coefficient between changes in dose and HbA1c was -0.9043. The estimated regression line formula was -0.964 × change in HbA1c+2.000. A starting dose of 0.15 U/kg/day was applicable to all background-subgroups except for patients with retinopathy (0.120 U/kg/day) and/or with eGFR<60 mL/min/1.73 m(2) (0.114 U/kg/day). Additionally, women (0.135 U/kg/day) and patients with sulfonylureas (0.132 U/kg/day) received a slightly decreased starting dose.


CONCLUSIONS/SIGNIFICANCE
We suggest a simplified and pragmatic dose calculation formula for type 2 diabetes patients starting glargine BOT optimal daily dose at 24 weeks  =  starting dose (0.15×weight) + incremental dose (baseline HbA1c - target HbA1c+2). This formula should be further validated using other samples in a prospective follow-up, especially since several patient groups required lower starting doses.
An exploration of the relationship between software development process maturity and project performance

Software projects have a high rate of failure. Organizations have tried to reduce the rate through methodological approaches but with little perceived success. A model of software development maturity (the capability maturity model (CMM)) describes managerial processes that can be used to attack software development difficulties from the managerial control perspective at five maturity levels. Our study examined performance of projects in relation to the activities at these various levels of maturity. A survey of software engineers indicated that the activities associated with the managerial control of development related positively to project performance measures. However, not each level of maturity demonstrated observable benefits, indicating that greater caution is needed in the planning and implementation of the activities. # 2003 Elsevier B.V. All rights reserved.
Conditional Generators of Words Definitions

We explore recently introduced definition modeling technique that provided the tool for evaluation of different distributed vector representations of words through modeling dictionary definitions of words. In this work, we study the problem of word ambiguities in definition modeling and propose a possible solution by employing latent variable modeling and soft attention mechanisms. Our quantitative and qualitative evaluation and analysis of the model shows that taking into account words ambiguity and polysemy leads to performance improvement.
PSA testing for prostate cancer: an online survey of the views and reported practice of General Practitioners in the UK

BACKGROUND
The role of Prostate Specific Antigen (PSA) testing in the early detection of prostate cancer is controversial. Current UK policy stipulates that any man who wishes to have a PSA test should have access to the test, provided he has been given full information about the benefits and limitations of testing. This study aimed to determine UK GPs' current reported practice regarding PSA testing, and their views towards informed decision-making and PSA testing.


METHOD
Online questionnaire survey, with a sample of 421 GPs randomly selected from a database of GPs across the UK.


RESULTS
95% (400/421) of GPs responded. 76% of GPs reported having performed a PSA test for an asymptomatic man at least once in the previous three months, with 13% reported having tested more than five men in this period. A majority of GPs reported they would do a PSA test for men presenting with a family history and requesting a test, for asymptomatic men requesting a test and also for men presenting with lower urinary tract symptoms. Reported testing rates were highest for men with a family history. Amongst men with lower urinary tract symptoms and men with no symptoms, reported testing rates were significantly higher for older than younger men. The majority of GPs expressed support for the current policy (67%), and favoured both the general practitioner and the man being involved in the decision making process (83%). 90% of GPs indicated that they would discuss the benefits and limitation of testing with the man, with most (61%) preferring to ask the man to make a further appointment if he decides to be tested.


CONCLUSION
This study indicates that PSA testing in asymptomatic men is a regular occurrence in the UK, and that there is general support from GPs for the current policy of making PSA tests available to 'informed' men who are concerned about prostate cancer. While most GPs indicated they would discuss the benefits and limitations prior to PSA testing, and most GPs favoured a shared approach to decision making, it is not known to what extent men are actually being informed. Research is needed to evaluate the most effective approach to assisting men in making an informed decision about whether or not to have a PSA test.
Associations of Physical Activity, Screen Time with Depression, Anxiety and Sleep Quality among Chinese College Freshmen

OBJECTIVES
To investigate the independent and interactive associations of physical activity (PA) and screen time (ST) with depression, anxiety and sleep quality among Chinese college students.


METHODS
A cross-sectional study was conducted in Wuhan University, China from November to December 2011. The students reported their PA, ST and socio-economic characteristics using self-administered questionnaires. Sleep quality was measured by the Pittsburgh Sleep Quality Index (PSQI). Depression and anxiety were assessed using the Self-rating Depression Scale (SDS) and Self-rating Anxiety Scale (SAS), respectively. Multivariate logistic regression models were used to estimate the odds ratios (ORs) and 95% confidence intervals (CIs) of the independent and interactive relationships of PA and ST with depression, anxiety and sleep quality.


RESULTS
A total of 1106 freshmen (471 females and 635 males) aged 18.9±0.9 years were included in the study. After adjustment for potential confounders, high PA and low ST were independently associated with significantly lower risks for poor sleep quality (OR: 0.48, 95% CI: 0.30-0.78) and depression (OR: 0.67, 95%CI: 0.44-0.89), respectively. An interactive inverse association was observed for combined effects of PA and low ST on depression (OR: 0.62, 95%CI: 0.40-0.92) and sleep quality (OR: 0.51, 95%CI: 0.27-0.91). No statistically significant associations were found between PA, ST and anxiety among the participants.


CONCLUSIONS
These findings suggest an independent and interactive relationship of high PA and low ST with significantly reduced prevalence of depressive problems and favorable sleep quality among Chinese college freshmen.
Mapping ICT use at home and telecommuting practices: A perspective from work/family border theory

This study draws on the work/family border theory to investigate the role of information communication technology (ICT) use at home in shaping the characteristics of work/family borders (i.e. flexibility and permeability) and consequently influencing individuals’ perceived work-family conflict, technostress, and level of telecommuting. Data were collected from a probability sample of 509 information workers in Hong Kong who were not selfemployed. The results showed that the more that people used ICT to do their work at home, the greater they perceived their work/family borders flexible and permeable. Interestingly, low flexibility and high permeability, rather than the use of ICT at home, had much stronger influences on increasing, in particular, family-to-work conflict. As expected, work-tofamily conflict was significantly and positively associated with technostress. Results also showed that the telecommuters tended to be older, had lower family incomes, used ICT frequently at home, and had a permeable boundary that allowed work to penetrate their home domain. The theoretical and practical implications are discussed. 2016 Elsevier Ltd. All rights reserved.
Using infrared sensors for distance measurement in mobile robots

9 The amplitude response of infrared (IR) sensors based on reflected amplitude of the surrounding objects is non-linear and depends on the reflectance characteristics of the object surface. As a result, the main use of IR sensors in robotics is for obstacle avoidance. Nevertheless, their inherently fast response is very attractive for enhancing the real-time operation of a mobile robot in, for instance, map building tasks. Thus, it seems that the development of new low-cost IR sensors able to accurately measure distances with reduced response times is worth researching. In this paper, a new IR sensor based on the light intensity back-scattered from objects and able to measure distances of up to 1 m is described. Also, the sensor model is described and the expected errors in distance estimates are analysed and modelled. Finally, the experimental results obtained are discussed. © 2002 Published by Elsevier Science B.V. 10
Rhyming schemes: Crossings and coverings

Some recent results on the enumeration of relations on finite totally ordered sets are unified by establishing correspondences between these relations and some types of rhyming scheme which are characterized by the planarity of certain graphical representations. These representations themselves and a systematic method of enumeration involving them are sketched. Interpretations and proofs of a number of combinatorial identities are obtained.
When cheese gets the blues: Pseudomonas fluorescens as the causative agent of cheese spoilage.

A bacterial contamination of fresh, low-acid cheese that resulted in production of a blue fluorescent pigment on the surface of the cheese was determined to be caused by Pseudomonas fluorescens biovar IV, a gram-negative bacteria that produces a blue, nondiffusible pigment as well as the soluble pigment pyoverdin, which fluoresces under UV light. Ten isolates collected from contaminated cheese and environmental samples were initially identified as P. fluorescens using 16S rDNA sequencing, but only 8 of the isolates produced blue pigment and fluoresced under UV light when re-inoculated onto fresh, low-acid cheese. The Biolog Metabolic Fingerprint system (Biolog Inc., Hayward, CA) and the Analytical Profile Index (BioMerieux Vitek Inc., Hazelwood, MO) for nonenteric gram-negative species as well as EcoRI ribotyping did not differentiate between the isolates that produced blue color and those that did not. Pulsed field gel electrophoresis with the enzyme XbaI was able to distinguish between the isolates that produced pigment and those that did not and allowed for identification of a specific environmental site (i.e., an overhead cheese vat agitator system) as the likely source of product contamination.
The efficacy of 5% topical tea tree oil gel in mild to moderate acne vulgaris: a randomized, double-blind placebo-controlled study.

BACKGROUND
Finding an effective treatment for acne that is well tolerated by the patients is a challenge. One study has suggested the efficacy of tea tree oil in treatment of the acne vulgaris.


AIM
To determine the efficacy of tea tree oil in mild to moderate acne vulgaris.


METHODS
This was a randomized double-blind clinical trial performed in 60 patients with mild to moderate acne vulgaris. They were randomly divided into two groups and were treated with tea tree oil gel (n=30) or placebo (n=30). They were followed every 15 days for a period of 45 days. Response to treatment was evaluated by the total acne lesions counting (TLC) and acne severity index (ASI). The data was analyzed statistically using t-test and by SPSS program.


RESULTS
There were no significant differences regarding demographic characteristics between the two groups. There was a significant difference between tea tree oil gel and placebo in the improvement of the TLC and also regarding improvement of the ASI. In terms of TLC and ASI, tea tree oil gel was 3.55 times and 5.75 times more effective than placebo respectively. Side-effects with both groups were relatively similar and tolerable.


CONCLUSION
Topical 5% tea tree oil is an effective treatment for mild to moderate acne vulgaris.
SAMI: Service-based arbitrated multi-tier infrastructure for Mobile Cloud Computing

Mobile Cloud Computing (MCC) is the state-of-the-art mobile computing technology aims to alleviate resource poverty of mobile devices. Recently, several approaches and techniques have been proposed to augment mobile devices by leveraging cloud computing. However, long-WAN latency and trust are still two major issues in MCC that hinder its vision. In this paper, we analyze MCC and discuss its issues. We leverage Service Oriented Architecture (SOA) to propose an arbitrated multi-tier infrastructure model named SAMI for MCC. Our architecture consists of three major layers, namely SOA, arbitrator, and infrastructure. The main strength of this architecture is in its multi-tier infrastructure layer which leverages infrastructures from three main sources of Clouds, Mobile Network Operators (MNOs), and MNOs' authorized dealers. On top of the infrastructure layer, an arbitrator layer is designed to classify Services and allocate them the suitable resources based on several metrics such as resource requirement, latency and security. Utilizing SAMI facilitate development and deployment of service-based platform-neutral mobile applications.