LLukas22/scidocs huggingface dataset:
Auditory}visual integration of talker gender in vowel perception

The experiments reported here used auditory}visual mismatches to compare three approaches to speaker normalization in speech perception: radical invariance, vocal tract normalization, and talker normalization. In contrast to the "rst two, the talker normalization theory assumes that listeners' subjective, abstract impressions of talkers play a role in speech perception. Experiment 1 found that the gender of a visually presented face a!ects the location of the phoneme boundary between [υ] and [S] in the perceptual identi"cation of a continuum of auditory}visual stimuli ranging from hood to hud. This e!ect was found for both &&stereotypical'' and &&non-stereotypical''male and female voices. The experiment also found that voice stereotypicality had an e!ect on the phoneme boundary. The di!erence between male and female talkers was greater when the talkers were rated by listeners as &&stereotypical''. Interestingly, for the two female talkers in this experiment, rated stereotypicality was correlated with voice breathiness rather than vowel fundamental frequency. Experiment 2 replicated and extended experiment 1 and tested whether the visual stimuli in experiment 1 were being perceptually integrated with the acoustic stimuli. In addition to the e!ects found in experiment 1, there was a boundary e!ect for the visually presented word: listeners responded hood more frequently when the acoustic stimulus was paired with a movie clip of a talker saying hood. Experiment 3 tested the abstractness of the talker information used in speech perception. Rather than seeing movie clips of male and female talkers, listeners were instructed to imagine a male or female talker while performing an audio-only identi"cation task with a gender-ambiguous hood-hud continuum. The phoneme boundary di!ered as a function of the imagined gender of the talker. The results from these experiments suggest that listeners integrate abstract gender information with phonetic information in speech perception. This conclusion supports the talker normalization theory of perceptual speaker normalization. ( 1999 Academic Press
Titanium allergy in dental implant patients: a clinical study on 1500 consecutive patients.

BACKGROUND
In dentistry, allergic reactions to Ti implants have not been studied, nor considered by professionals. Placing permanent metal dental implants in allergic patients can provoke type IV or I reactions. Several symptoms have been described, from skin rashes and implant failure, to non-specific immune suppression.


OBJECTIVE
Our objective was to evaluate the presence of titanium allergy by the anamnesis and examination of patients, together with the selective use of cutaneous and epicutaneous testing, in patients treated with or intending to receive dental implants of such material.


MATERIAL AND METHODS
Thirty-five subjects out of 1500 implant patients treated and/or examined (2002-2004) were selected for Ti allergy analysis. Sixteen presented allergic symptoms after implant placement or unexplained implant failures [allergy compatible response group (ACRG)], while 19 had a history of other allergies, or were heavily Ti exposed during implant surgeries or had explained implant failures [predisposing factors group (PFG)]. Thirty-five controls were randomly selected (CG) in the Allergy Centre. Cutaneous and epicutaneous tests were carried out.


RESULTS
Nine out of the 1500 patients displayed positive (+) reactions to Ti allergy tests (0.6%): eight in the ACRG (50%), one in the PFG (5.3%)(P=0.009) and zero in the control group. Five positives were unexplained implant failures (five out of eight).


CONCLUSIONS
Ti allergy can be detected in dental implant patients, even though its estimated prevalence is low (0.6%). A significantly higher risk of positive allergic reaction was found in patients showing post-op allergy compatible response (ACRG), in which cases allergy tests could be recommended.
The Relationship between Turgor Pressure Change and Cell Hydraulics of Midrib Parenchyma Cells in the Leaves of Zea mays

Leaf dehydration decreases water potential and cell turgor pressure. Therefore, changes in cell turgor pressure may regulate water transport across plant cell membranes. Using a cell pressure probe, the hydraulic properties of parenchyma cells in the midrib of maize (Zea mays L.) leaves were measured (half time of water exchange in cells as a measure of hydraulic conductivity Lp). Using intact plants with root systems encased in a pressure chamber, the root systems were pressurized and the turgor pressure in leaf cells increased by increments up to 0.3 MPa. However, the increase in the cell turgor did not increase but stabilized values. Increased water potential in leaf cells seemed to have stabilizing effects on the probably due to enhanced water availability. When the cell turgor decreased by 0.1 MPa to 0.3 MPa with releasing the pressure in the pressure chamber, was temporarily increased to a large degree,a factor of up to 13 within 30 min.
A Downlink Performance Analysis of VoIP Services Over an IEEE 802.16e OFDMA System

The voice-over-Internet protocol (VoIP) service is expected to be widely supported in wireless mobile networks, though its feasibility and capacity have not been studied in relation to the emerging IEEE 802.16e orthogonal frequency division multiple access (OFDMA) system. Using analytical and simulation models that we developed, we present the downlink performance of VoIP services over an IEEE 802.16e OFDMA system
Analysis of relapses in anti-NMDAR encephalitis.

OBJECTIVE
The clinical characteristics of patients with relapsing anti-NMDA receptor (NMDAR) encephalitis are not well-defined. In this study, we report the clinical profile and outcome of relapses in a series of anti-NMDAR encephalitis.


METHODS
We did a retrospective review of relapses that occurred in 25 patients with anti-NMDAR encephalitis. Relapses were defined as any new psychiatric or neurologic syndrome, not explained by other causes, which improved after immunotherapy or, less frequently, spontaneously.


RESULTS
A total of 13 relapses were identified in 6 patients. Four of them had several, 2 to 4, relapses. There was a median delay of 2 years (range 0.5 to 13 years) for the first relapse. Median relapse rate was 0.52 relapses/patient-year. Relapse risk was higher in patients who did not receive immunotherapy in the first episode (p = 0.009). Most cases (53%) presented partial syndromes of the typical anti-NMDAR encephalitis. Main symptoms of relapses were speech dysfunction (61%), psychiatric (54%), consciousness-attention disturbance (38%), and seizures (31%). Three relapses (23%) presented with isolated atypical symptoms suggestive of brainstem-cerebellar involvement. An ovarian teratoma was detected at relapse in only 1 patient (17%). Relapses did not add residual deficit to that caused by the first episode.


CONCLUSIONS
Relapses in anti-NMDAR encephalitis are common (24%). They may occur many years after the initial episode. Relapses may present with partial aspects or with isolated symptoms of the full-blown syndrome. Immunotherapy at first episode reduces the risk of relapses.
Alar setback technique: a controlled method of nasal tip deprojection.

OBJECTIVES
To describe an alar cartilage-modifying technique aimed at decreasing nasal tip projection in cases with overdeveloped alar cartilages and to compare it with other deprojection techniques used to correct such deformity.


DESIGN
Selected case series.


SETTINGS
University and private practice settings in Alexandria, Egypt.


PATIENTS
Twenty patients presenting for rhinoplasty who had overprojected nasal tips primarily due to overdeveloped alar cartilages. All cases were primary cases except for one patient, who had undergone 2 previous rhinoplasties.


INTERVENTION
An external rhinoplasty approach was used to set back the alar cartilages by shortening their medial and lateral crura. The choice of performing a high or low setback depended on the preexisting lobule-to-columella ratio. Following the setback, the alar cartilages were reconstructed in a fashion that increased the strength and stability of the tip complex.


MAIN OUTCOME MEASURES
Subjective evaluation included clinical examination, analysis of preoperative and postoperative photographs, and patient satisfaction. Objective evaluation of nasal tip projection, using the Goode ratio and the nasofacial angle, was performed preoperatively and repeated at least 6 months postoperatively.


RESULTS
A low setback was performed in 16 cases (80%) and a high setback in 4 (20%). The mean follow-up period was 18 months (range, 6-36 months). The technique effectively deprojected the nasal tip as evidenced by the considerable postoperative decrease in values of the Goode ratio and the nasofacial angle. No complications were encountered and no revision surgical procedures were required.


CONCLUSIONS
The alar setback technique has many advantages; it results in precise predictable amounts of deprojection, controls the degree of tip rotation, preserves the natural contour of the nasal tip, respects the tip support mechanisms, increases the strength and stability of nasal tip complex, preserves or restores the normal lobule-to-columella proportion, and does not lead to alar flaring. However, the technique requires an external rhinoplasty approach and fine technical precision.
The Magpie Trial: a randomised trial comparing magnesium sulphate with placebo for pre-eclampsia. Outcome for children at 18 months

OBJECTIVE
To assess the long-term effects of in utero exposure to magnesium sulphate for children whose mothers had pre-eclampsia.


DESIGN
Assessment at 18 months of age for children whose mothers were recruited to the Magpie Trial (recruitment 1998-2001 ISRCTN 86938761), which compared magnesium sulphate with placebo.


SETTING
Follow-up of children born at 125 centres in 19 countries across five continents.


POPULATION
A total of 6922 children were born to women randomised before delivery at follow-up centres. Of these, 2271 were not included for logistic reasons and 168 were excluded (101 at a centre where <20% were contacted, 40 whose death or disability was due to a problem at conception or embryogenesis and 27 whose parent/s opted out). Therefore, 4483 children were included in follow-up, of whom 3283 (73%) were contacted.


METHODS
Assessment by questionnaire, with interview and neurodevelopmental testing of selected children.


MAIN OUTCOME MEASURES
Death or neurosensory disability at age of 18 months.


RESULTS
Of those allocated magnesium sulphate, 245/1635 (15.0%) were dead or had neurosensory disability at 18 months compared with 233/1648 (14.1%) allocated placebo (relative risk [RR] 1.06, 95% CI 0.90-1.25), and of survivors, 19/1409 (1.3%) had neurosensory disability at 18 months compared with 27/1442 (1.9%) (RR 0.72, 95% CI 0.40-1.29). There were no substantial differences in causes of death or in the risk of individual impairments or disabilities.


CONCLUSIONS
The lower risk of eclampsia following prophylaxis with magnesium sulphate was not associated with a clear difference in the risk of death or disability for children at 18 months.
Differential Privacy

In 1977 Dalenius articulated a desideratum for statistical databases: nothing about an individual should be learnable from the database that cannot be learned without access to the database. We give a general impossibility result showing that a formalization of Dalenius’ goal along the lines of semantic security cannot be achieved. Contrary to intuition, a variant of the result threatens the privacy even of someone not in the database. This state of affairs suggests a new measure, differential privacy, which, intuitively, captures the increased risk to one’s privacy incurred by participating in a database. The techniques developed in a sequence of papers [8, 13, 3], culminating in those described in [12], can achieve any desired level of privacy under this measure. In many cases, extremely accurate information about the database can be provided while simultaneously ensuring very high levels of privacy.
IT managers' requisite skills

Matching job seekers' qualifications with employers' skill requirements.
Centers of excellence: a new dimension in surgical education.

Surgical education has always been challenging and is being made more difficult with the changes in the surgical environment. In the past decade, the number of patients available for educational purposes has decreased because of the development of technology that has significantly reduced their time of stay in the hospital and has also moved many surgical procedures to ambulatory services. Technologic advances also create the demand for more specialized training. The increased number of undergraduate, postgraduate students, and clinical fellows has also affected the educational mandate of the academic hospitals. Alternative ways to teach medicine, and especially surgery, are becoming inevitable. One such method is to teach students outside the operating room in a simulated environment. This article reports on the developments of surgical education centers and provides guidance for those who might wish to develop such educational facilities. For further information, visit www.cesei.org.
A reexamination of a childhood cancer stereotype.

OBJECTIVE
To examine whether young adults have stereotypical beliefs toward children who have been treated for cancer.


METHODS
Undergraduate participants read a vignette describing a child labeled either healthy (HL), in remission from cancer and no longer undergoing treatment (RCL), or in remission and still undergoing treatment (RCTL) and rated the child on the Ratings of the Child Questionnaire (ROCQ). Univariate and multivariate analyses of variance were conducted.


RESULTS
Participants rated the HL child more positively than the RCL or RCTL child; the RCL and RCTL child ratings did not differ. Females evaluated the child more positively than did males.


CONCLUSIONS
These results support previous findings of a childhood cancer stereotype. However, effect sizes were small, which may indicate a weak stereotype with these specific participants.
Asymmetric collimation can significantly reduce patient radiation dose during pulmonary vein isolation.

AIMS
Current fluoroscopic and 3D image-guided treatment of atrial fibrillation (AF) by radiofrequency ablation is characterized by a substantial amount of X-ray radiation. We investigated the potential of an asymmetric collimation technique to reduce dose.


METHODS AND RESULTS
For 30 patients, referred for AF ablation, we determined the received fluoroscopy dose for various collimation scenarios: a single collimation window encompassing all veins as used in most labs (Sc 1), an optimal adjusted symmetric collimation window encompassing each two ipsilateral veins (Sc 2) or each individual vein (Sc 3) and an optimal asymmetric collimation window encompassing each two ipsilateral veins (Sc 4) or each individual vein (Sc 5). Twenty patients were studied retrospectively and 10 were studied prospectively. Total fluoroscopy effective dose for all collimation strategies amounted to 45 ± 31 mSv for a single collimation field (Sc 1), 36 ± 25 mSv (Sc 2), and 24 ± 14 mSv (Sc 3) for a symmetrically adjusted collimation window and 15 ± 10 (Sc 4) and 5 ± 3 mSv (Sc 5) for an asymmetrically adjusted collimation approach. Validation of symmetric (Sc 2) and asymmetric (Sc 4) collimation in 10 patients confirmed the retrospective analysis.


CONCLUSIONS
Implementation and effective application of an optimal asymmetric collimation approach would yield an average three- to nine-fold reduction of fluoroscopy dose during AF ablation procedures. This reduction exceeds what has been previously reported by implementing an electromagnetic catheter tracking approach. Furthermore, it can be easily integrated in the clinical workflow with limited additional one-time cost. Manufacturers of imaging systems should consider its implementation a priority, and physicians should adopt it in their workflow.
Thermal properties of single-phase Y2SiO5

Y(2)SiO(5) is a promising candidate for oxidation-resistant or environmental/thermal barrier coatings (ETBC) due to its excellent high-temperature stability, low elastic modulus and low oxygen permeability. In this paper, we investigated the thermal properties Of Y2SiO5 comprehensively, including thermal expansion, thermal diffusivity, heat capacity and thermal conductivity. It is interesting that Y(2)SiO(5) has a very low thermal conductivity (similar to 1.40 W/m K) but a relatively high linear thermal expansion coefficient ((8.36 +/- 0.5) x 10(-6) K(-1)), suggesting compatible thermal and mechanical properties to some non-oxide ceramics and nickel superalloys as ETBC layer. Y(2)SiO(5) is also an ideal EBC on YSZ TBC layer due to their close thermal expansion coefficients. As a continuous source of Y(3+), it is predicted that Y(2)SiO(5) EBC may prolong the lifetime of zirconia-based TBC by stopping the degradation aroused by the loss of Y stabilizer. (C) 2008 Elsevier Ltd. All rights reserved.
Efficacy of Fish Oil on Serum of TNFα, IL-1β, and IL-6 Oxidative Stress Markers in Multiple Sclerosis Treated with Interferon Beta-1b

UNLABELLED
Multiple sclerosis (MS) is a chronic inflammatory disease, which leads to focal plaques of demyelination and tissue injury in the central nervous system. Oxidative stress is also thought to promote tissue damage in multiple sclerosis. Current research findings suggest that omega-3 polyunsaturated fatty acids (PUFAs) such as eicosapenta-enoic acid (EPA) and docosahexaenoic acid (DHA) contained in fish oil may have anti-inflammatory, antioxidant, and neuroprotective effects. The aim of the present work was to evaluate the efficacy of fish oil supplementation on serum proinflammatory cytokine levels, oxidative stress markers, and disease progression in MS. 50 patients with relapsing-remitting MS were enrolled. The experimental group received orally 4 g/day of fish oil for 12 months. The primary outcome was serum TNF α levels; secondary outcomes were IL-1 β 1b, IL-6, nitric oxide catabolites, lipoperoxides, progression on the expanded disability status scale (EDSS), and annualized relapses rate (ARR). Fish oil treatment decreased the serum levels of TNF α , IL-1 β , IL-6, and nitric oxide metabolites compared with placebo group (P ≤ 0.001). There was no significant difference in serum lipoperoxide levels during the study. No differences in EDSS and ARR were found.


CONCLUSION
Fish oil supplementation is highly effective in reducing the levels of cytokines and nitric oxide catabolites in patients with relapsing-remitting MS.
An aldol-based build/couple/pair strategy for the synthesis of medium- and large-sized rings: discovery of macrocyclic histone deacetylase inhibitors.

An aldol-based build/couple/pair (B/C/P) strategy was applied to generate a collection of stereochemically and skeletally diverse small molecules. In the build phase, a series of asymmetric syn- and anti-aldol reactions were performed to produce four stereoisomers of a Boc-protected γ-amino acid. In addition, both stereoisomers of O-PMB-protected alaninol were generated to provide a chiral amine coupling partner. In the couple step, eight stereoisomeric amides were synthesized by coupling the chiral acid and amine building blocks. The amides were subsequently reduced to generate the corresponding secondary amines. In the pair phase, three different reactions were employed to enable intramolecular ring-forming processes: nucleophilic aromatic substitution (S(N)Ar), Huisgen [3+2] cycloaddition, and ring-closing metathesis (RCM). Despite some stereochemical dependencies, the ring-forming reactions were optimized to proceed with good to excellent yields, providing a variety of skeletons ranging in size from 8- to 14-membered rings. Scaffolds resulting from the RCM pairing reaction were diversified on the solid phase to yield a 14 400-membered library of macrolactams. Screening of this library led to the discovery of a novel class of histone deacetylase inhibitors, which display mixed enzyme inhibition, and led to increased levels of acetylation in a primary mouse neuron culture. The development of stereo-structure/activity relationships was made possible by screening all 16 stereoisomers of the macrolactams produced through the aldol-based B/C/P strategy.
Application and Revision of Montreal Cognitive Assessment in China's Military Retirees with Mild Cognitive Impairment.

OBJECTIVE
In an effort to accommodate MOCA to better fit for the Chinese context, this study was designed to employ the MOCA criteria to screen mild cognitive impairment (MCI) and analyze associated risk factors in military retirees.


METHODS
Three hundred and four retired military cadres were recruited using a random cluster sampling technique with information collected including personal, prevalence, MOCA scale, and related neuropsychiatry scale. Thirty retirees were randomly chosen to be further analyzed one month later using the revised MOCA scale.


RESULTS
①Our data indicated an incidence rate of 64.8% for mild cognitive impairment in retired military cadres. The incidence rate for MCI was significantly higher in those aged 80 or above compared with those 80 years of age or younger (P<0.05). The incidence rate of MCI was significantly higher in those with fewer than 6 years of education compared with those with over 7 years of education (P<0.05). The MCI incidence was higher for those with little exercise than those taking regular exercise (P<0.01). Moreover, the MCI incidence was higher in stroke patients than those who never had a stroke episode (P<0.05). ②There was a significant correlation between MOCA and MMSE scale scores (r = 0.81). MOCA scale scores were negatively correlated with ADL and CES-D scores (although not PSQI scores). ③ MOCA recension Cronbach's alpha value was 0.862. The related coefficient of MOCA and MOCA recension was 0.878(P<0.01). When the Score of cut-off -point of the MOCA recension was 28, the area in ROC curve analyses was 0.859, as well as the largest area.


CONCLUSION
Retired cadres exhibited a greater incidence of MCI (than general population), which was closely associated with age, level of education and physical exercise and cerebral apoplexy. Revised MOCA scale displays a better validity and reaction degree of reliability and is more suitable for screening and diagnosis of MCI in the elderly in China.