LLukas22/scidocs huggingface dataset:
The relationship between population-level exposure to alcohol advertising on television and brand-specific consumption among underage youth in the US.

AIMS
We investigated the population-level relationship between exposure to brand-specific advertising and brand-specific alcohol use among US youth.


METHODS
We conducted an internet survey of a national sample of 1031 youth, ages 13-20, who had consumed alcohol in the past 30 days. We ascertained all of the alcohol brands respondents consumed in the past 30 days, as well as which of 20 popular television shows they had viewed during that time period. Using a negative binomial regression model, we examined the relationship between aggregated brand-specific exposure to alcohol advertising on the 20 television shows [ad stock, measured in gross rating points (GRPs)] and youth brand-consumption prevalence, while controlling for the average price and overall market share of each brand.


RESULTS
Brands with advertising exposure on the 20 television shows had a consumption prevalence about four times higher than brands not advertising on those shows. Brand-level advertising elasticity of demand varied by exposure level, with higher elasticity in the lower exposure range. The estimated advertising elasticity of 0.63 in the lower exposure range indicates that for each 1% increase in advertising exposure, a brand's youth consumption prevalence increases by 0.63%.


CONCLUSIONS
At the population level, underage youths' exposure to brand-specific advertising was a significant predictor of the consumption prevalence of that brand, independent of each brand's price and overall market share. The non-linearity of the observed relationship suggests that youth advertising exposure may need to be lowered substantially in order to decrease consumption of the most heavily advertised brands.
Minimum-Area Rectangle Containing a Set of Points

3 The Rotating Calipers Algorithm 3 3.1 Computing the Initial Rectangle . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 3.2 Updating the Rectangle . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 3.2.1 Distinct Supporting Vertices . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 3.2.2 Duplicate Supporting Vertices . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 3.2.3 Multiple Polygon Edges Attain Minimum Angle . . . . . . . . . . . . . . . . . . . . . 8 3.2.4 The General Update Step . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10
Feasibility study of a hybrid PV-micro hydro system for rural electrification

The present study investigates the possibility of using a stand-alone solar/micro hydro hybrid power system for low-cost electricity production which can satisfy the energy load requirements of a typical remote and isolated rural area. In this context, the optimal dimensions to improve the technical and economical performances of the hybrid system are determined according to the load energy requirements, the solar and water resources and the importance of supply continuity. The proposed system's installation and operating costs are simulated using the Hybrid Optimization Model for Electric Renewable (HOMER) with the stream flow, the solar radiation and the system components costs as inputs; and then compared with those of other supply options such as grid extension and diesel generation.
Spatio-temporal avalanche forecasting with Support Vector Machines

This paper explores the use of the Support Vector Machine (SVM) as a data exploration tool and a predictive engine for spatio-temporal forecasting of snow avalanches. Based on the historical observations of avalanche activity, meteorological conditions and snowpack observations in the field, an SVM is used to build a data-driven spatio-temporal forecast for the local mountain region. It incorporates the outputs of simple physics-based and statistical approaches used to interpolate meteorological and snowpack-related data over a digital elevation model of the region. The interpretation of the produced forecast is discussed, and the quality of the model is validated using observations and avalanche bulletins of the recent years. The insight into the model behaviour is presented to highlight the interpretability of the model, its abilities to produce reliable forecasts for individual avalanche paths and sensitivity to input data. Estimates of prediction uncertainty are obtained with ensemble forecasting. The case study was carried out using data from the avalanche forecasting service in the Locaber region of Scotland, where avalanches are forecast on a daily basis during the winter months. DOI: https://doi.org/10.5194/nhess-11-367-2011 Posted at the Zurich Open Repository and Archive, University of Zurich ZORA URL: https://doi.org/10.5167/uzh-52743 Published Version Originally published at: Pozdnoukhov, Alexei; Matasci, Giona; Kanevski, Mikhail; Purves, Ross S (2011). Spatio-temporal avalanche forecasting with support vector machines. Natural Hazards and Earth System Sciences, 11(2):367-382. DOI: https://doi.org/10.5194/nhess-11-367-2011 Nat. Hazards Earth Syst. Sci., 11, 367–382, 2011 www.nat-hazards-earth-syst-sci.net/11/367/2011/ doi:10.5194/nhess-11-367-2011 © Author(s) 2011. CC Attribution 3.0 License. Natural Hazards
Duane -Hunt relation improved

In present paper the Duane-Hunt relation for direct measurement of the Planck constant is improved by including of relativistic corrections. New relation to determine the Planck constant, suggested in this paper contains Duane-Hunt relation as …rst term and can be applied in a wide range of energies.
Investigation and management of iron deficiency anaemia in general practice: a cluster randomised controlled trial of a simple management prompt.

BACKGROUND
Iron deficiency anaemia (IDA) remains the most common cause of anaemia and is frequently secondary to occult gastrointestinal blood loss requiring further investigation. The study was designed to prospectively assess the adequacy of investigation of IDA and to establish whether a simple computerised prompt would increase the completeness of investigation of patients presenting to their general practitioners.


PATIENTS AND METHODS
All men aged >20 and women aged >50 newly found to have a probable IDA (n=431) in primary care were randomised according to general practice (n=89) to one of two computer generated prompts, by the haematology laboratories in two large district general hospitals. Data were collected 12 months after the index date. The primary outcome measure was the adequacy of investigation of the cause of anaemia. Multiple logistic regression was used to analyse each binary outcome.


RESULTS
Two hundred and three (47%) of 431 patients presenting to their general practitioner with an IDA were adequately managed and 140/357 (39%) of patients who were otherwise fit for investigation had no tests at all. Twenty one (17%) of 125 patients who did have adequate investigation at the time of presentation were found to have colorectal cancer. Only 30% of patients had a confirmed diagnosis within 12 months. The prompt did not affect the level of investigation (odds ratio 0.88, 95% confidence interval (CI) 0.60 to 1.29, p=0.52). The initial prescribing of oral iron was improved (odds ratio 2.19, 95% CI 1.27 to 3.77, p=0.005), but not the documented prescribing of a full therapeutic course or the use of follow up blood counts.


CONCLUSIONS
The investigation and management of IDA presenting in general practice remains inadequate and is not improved by a simple management prompt.
Multi-linear Monte Carlo simulation method for probabilistic load flow of distribution systems with wind and photovoltaic generation systems

In this paper, a probabilistic method is proposed to analyze the steady-state operating conditions of an active electrical distribution system with Wind (WD) and Photovoltaic (PV) generation plants. This method takes into account the uncertainties of power load demands and power production from renewable generation systems and combines Monte Carlo simulation techniques and multi-linearized power flow equations. The power flow equations include models of wind turbine and PV generation units and multi-linearization is accomplished by applying a criterion based on the total active power of the system. The method properly extends a probabilistic method proposed in the relevant literature for traditional passive electrical distribution systems to the field of an active electrical distribution system with WD and PV generation units. Numerical applications are presented and discussed with reference to a 17-bus test distribution system characterized by WD and PV systems connected at different busbars. The results obtained with the proposed algorithm are compared with the results obtained using a Monte Carlo simulation algorithm that included non-linear power flow equations. © 2014 Elsevier Ltd. All rights reserved.
Estimation of birth population-based perinatal-neonatal mortality and preterm rate in China from a regional survey in 2010

OBJECTIVE
To estimate birth population-based perinatal-neonatal mortality and preterm rate in China from a regional survey in 2010.


STUDY DESIGN
Data of total births in 2010 obtained from 151 level I-III hospitals in Huai'an, Jiangsu, were prospectively collected and analyzed.


RESULTS
From 61,227 birth registries (including 60,986 live births and 241 stillbirths), we derive a birth rate of 11.3‰ (of 5.4 million regional population), a male-to-female ratio of 116:100 and valid data from 60,615 newborns. Mean birth weight (BW) was 3441 ± 491 g with 13.6% macrosomia. Low BW was 2.8% (1691/60,372) with 8.83% mortality. Preterm rate was 3.72% (2239/60,264) with 7.61% mortality. Cesarean section rate was 52.9% (31,964/60,445), multiple pregnancy 1.8% (1088/60,567) and birth defects 6.7‰ (411/61,227). There were 97.4% healthy newborns and 2.2% (1298) requiring hospitalized after birth. The perinatal mortality was 7.7‰ (471/61,227, including 241 stillbirths, 230 early neonatal deaths). The neonatal mortality was 4.4‰ (269/60,986). The main causes of neonatal death were birth asphyxia (24.5%), respiratory diseases (21.5%), prematurity related organ dysfunction (18.5%) and congenital anomalies (7.7%), whereas incidence of congenital heart disease and respiratory distress syndrome was 8.6‰ and 6.1‰, respectively.


CONCLUSIONS
This regional birth population-based data file contains low perinatal-neonatal mortality rates, associated with low proportion of LBW and preterm births, and incidences of major neonatal disease, by which we estimate, in a nationwide perspective, in 16 million annual births, preterm births should be around 800,000, perinatal and neonatal mortality may be 128,000-144,000 and 80,000-96,000, respectively, along with 100,000 respiratory distress syndrome.
The Impact of Using Technology in Teaching English as a Second Language

This paper aims to highlight the role of using modern technology in teaching English as a second language. It discusses different approaches and techniques which can assist English language students to improve their learning skills by using technology. Among these techniques are online English language learning web sites, computer assisted language learning programs, presentation software, electronic dictionaries, chatting and email messaging programs, listening CD-players, and learning video-clips. A case study has been done to appreciate the response of typical English language classroom students for using technology in the learning process. Upon this practical study, the paper diagnoses the drawbacks and limitations of the current conventional English language learning tools, and concludes with certain suggestions and recommendations.
Scheduling operating rooms: achievements, challenges and pitfalls

In hospitals, the operating room (OR) is a particularly expensive facility and thus efficient scheduling is imperative. This can be greatly supported by using advanced methods that are discussed in the academic literature. In order to help researchers and practitioners to select new relevant articles, we classify the recent OR planning and scheduling literature into tables using patient type, used performance measures, decisions made, OR supporting units, uncertainty, research methodology and testing phase. Additionally, we identify promising practices and trends and recognize common pitfalls when researching OR scheduling. Our findings indicate, among others, that it is often unclear whether an article mainly targets researchers and thus contributes advanced methods or targets practitioners and consequently provides managerial insights. Moreover, many performance measures (e.g., overtime) are not always used in the correct context. Furthermore, we see that important information that would allow readers to determine whether the reported research results are relevant to them is often missing. In order to avoid these pitfalls, we conclude that researchers need to state whether they target researchers or practitioners, motivate the choice of the used performance measures and mention both setting and method specific assumptions. M. Samudra, C. Van Riet, E. Demeulemeester, B. Cardoen Faculty of Economics and Business, KU Leuven E-mail: carla.vanriet@kuleuven.be ( ) B. Cardoen Vlerick Business School, Faculty of Economics and Business, KU Leuven N. Vansteenkiste, F. Rademakers University hospital Leuven
The effects of multimodal exercise on cognitive and physical functioning and brain-derived neurotrophic factor in older women: a randomised controlled trial.

OBJECTIVE
to test the effect of a 16-week multimodal exercise program on neurocognitive and physical functioning and brain-derived neurotrophic factor (BDNF).


DESIGN
a single-blinded, parallel-group randomised controlled trial.


SETTINGS
university campus and community-based halls.


SUBJECTS
forty-nine women aged 65 to 75 years, with no cognitive impairment and not undertaking more than 1 h of formal exercise training per week.


METHODS
the intervention group attended a 60-min multimodal class twice each week which included cardiovascular, strength and motor fitness training. The primary outcome was neurocognitive functioning and secondary outcomes were physical functioning and plasma levels of BDNF.


RESULTS
twenty-five participants were randomised to the intervention group and 24 to the control group. One control participant withdrew before follow-up data collection. The intervention group performed significantly better than the control group at follow-up (when controlled for baseline) in the Trail Making test A and B, the California Older Adult Stroop test (Word, Interference and Total scores), Controlled Oral Word Association test and the Timed Up-and-Go test, Six-Minute Walk test, One-Legged Stance test and plasma BDNF.


CONCLUSION
this multimodal exercise program resulted in neurocognitive and physical performance improvements and increased levels of plasma BDNF, in older women, when compared with controls. This RCT provides evidence that a multimodal exercise intervention can achieve larger effect sizes than those generally resulting from single modality interventions. Increases in BDNF levels imply neurogenesis may be a component of the mechanism underpinning the cognitive improvements associated with multimodal exercise.


TRIAL REGISTRATION
Australian and New Zealand Clinical Trial Registration Number: ANZCTR12612000451808.
Aerobic interval training and continuous training equally improve aerobic exercise capacity in patients with coronary artery disease: the SAINTEX-CAD study.

BACKGROUND
Exercise-based cardiac rehabilitation increases peak oxygen uptake (peak VO₂), which is an important predictor of mortality in cardiac patients. However, it remains unclear which exercise characteristics are most effective for improving peak VO₂ in coronary artery disease (CAD) patients. Proof of concept papers comparing Aerobic Interval Training (AIT) and Moderate Continuous Training (MCT) were conducted in small sample sizes and findings were inconsistent and heterogeneous. Therefore, we aimed to compare the effects of AIT and Aerobic Continuous Training (ACT) on peak VO₂, peripheral endothelial function, cardiovascular risk factors, quality of life and safety, in a large multicentre study.


METHODS
Two-hundred CAD patients (LVEF >40%, 90% men, mean age 58.4 ± 9.1 years) were randomized to a supervised 12-week cardiac rehabilitation programme of three weekly sessions of either AIT (90-95% of peak heart rate (HR)) or ACT (70-75% of peak HR) on a bicycle. Primary outcome was peak VO₂; secondary outcomes were peripheral endothelial function, cardiovascular risk factors, quality of life and safety.


RESULTS
Peak VO₂ (ml/kg/min) increased significantly in both groups (AIT 22.7 ± 17.6% versus ACT 20.3 ± 15.3%; p-time<0.001). In addition, flow-mediated dilation (AIT+34.1% (range -69.8 to 646%) versus ACT+7.14% (range -66.7 to 503%); p-time<0.001) quality of life and some other cardiovascular risk factors including resting diastolic blood pressure and HDL-C improved significantly after training. Improvements were equal for both training interventions.


CONCLUSIONS
Contrary to earlier smaller trials, we observed similar improvements in exercise capacity and peripheral endothelial function following AIT and ACT in a large population of CAD patients.
A randomized, placebo-controlled proof-of-concept trial of adjunctive topiramate for alcohol use disorders in bipolar disorder.

BACKGROUND AND OBJECTIVES
Topiramate is effective for alcohol use disorders (AUDs) among non-psychiatric patients. We examined topiramate for treating comorbid AUDs in bipolar disorder (BD).


METHODS
Twelve participants were randomized to topiramate or placebo for 12 weeks.


RESULTS
The topiramate group, with two out of five participants (40%) completing treatment, experienced less improvement in drinking patterns than the placebo group, with five out of seven participants (71%) completing treatment.


DISCUSSION AND CONCLUSIONS
Topiramate did not improve drinking behavior and was not well-tolerated. This study failed to recruit adequately. Problems surrounding high attrition, a small study sample, and missing data preclude interpretation of study findings.


SCIENTIFIC SIGNIFICANCE
This is the first randomized, placebo-controlled trial of topiramate for AUDs in BD.
Separation of Craniopagus Twins over the Past 20 Years: A Systematic Review of the Variables That Lead to Successful Separation.

BACKGROUND
Attempted separation of craniopagus twins has continued to be associated with devastating results since the first partially successful separation with one surviving twin in 1952. To understand the factors that contribute to successful separation in the modern era of neuroimaging and modern surgical techniques, the authors reviewed and analyzed cases reported since 1995.


METHODS
All reported cases of craniopagus twin separation attempts from 1995 to 2015 were identified using PubMed (n = 19). In addition, the Internet was searched for additional unreported separation attempts (n = 5). The peer-reviewed cases were used to build a categorical database containing information on each twin pair, including sex; date of birth; date of surgery; multiple- versus single-stage surgery; angular versus vertical conjoining; nature of shared cerebral venous system; and the presence of other comorbidities identified as cardiovascular, genitourinary, and craniofacial. The data were analyzed to find factors associated with successful separation (survival of both twins at postoperative day 30).


RESULTS
Vertical craniopagus is associated with successful separation (p < 0.001). No statistical significance was attributed to the nature of the shared cerebral venous drainage or the other variables examined. Multiple-stage operations and surgery before 12 months of age are associated with a trend toward statistical significance for successful separation.


CONCLUSIONS
The authors' analysis indicates that vertical craniopagus twins have the highest likelihood of successful separation. Additional factors possibly associated with successful separation include the nature of the shared sinus system, surgery at a young age, and the use of staged separations.


CLINICAL QUESTION/LEVEL OF EVIDENCE
Therapeutic, V.
Nitrogenation of hafnium carbide powders in AC and DC plasma by Electrical Discharge Assisted Mechanical Milling

Abstract Metal carbonitride powders and coatings are well known as superhard materials which are widely applied in many engineering products. Of this group of materials hafnium carbonitride properties are one of the least known due to difficulties with preparation. In this study, the electric discharge assisted mechanical milling (EDAMM) method involving a nitrogen plasma together with mechanical milling was used to synthetise hafnium carbonitride powders within minutes. It was found that difficulties in conventional manufacturing methods, resulting in the formation of only thin layers instead of bulk materials can be overcome by applying the new technique, and HfC x N y powder could be successfully engineered with controlled amount of nitrogen uptake. In this investigation we studied the effects of AC and DC discharges on nitrogen solubility in HfC powder. Microstructure and phase evolution were determined using XRD and SEM, while the nitrogen content in the grains was evaluated by EDS and bulk nitrogen content by CHN analysis. Maximum solubilities of 3.42 wt% and 2.95 wt%N under DC an AC discharge currents, respectively, were obtained. Reaction paths varied depending on processing conditions with HfC x N y formed under DC discharge processing and mixed products containing HfC, several HfC x N y phases and HfN like phase formed after AC processing. After nitrogenation the most highly nitrided powders were subjected to 1 min additional EDAMM processing using high power discharges to allow the formation of large, sintered particles of sufficient size to perform hardness measurements on. Vickers harnesses of fully sintered large particles after 5 and 10 min of EDAMM were 1808 and 2169HV, respectively.
Withholding the artificial administration of fluids and food from elderly patients with dementia: ethnographic study.

OBJECTIVE
To clarify the practice of withholding the artificial administration of fluids and food from elderly patients with dementia in nursing homes.


DESIGN
Qualitative, ethnographic study in two phases.


SETTING
10 wards in two nursing homes in the Netherlands.


PARTICIPANTS
35 patients with dementia, eight doctors, 43 nurses, and 32 families.


RESULTS
The clinical course of dementia was considered normal and was rarely reason to begin the artificial administration of fluids and food in advanced disease. Fluids and food seemed to be given mainly when there was an acute illness or a condition that needed medical treatment and which required hydration to be effective. The medical condition of the patient, the wishes of the family, and the interpretations of the patients' quality of life by their care providers were considered more important than living wills and policy agreements.


CONCLUSIONS
Doctors' decisions about withholding the artificial administration of fluids and food from elderly patients with dementia are influenced more by the clinical course of the illness, the presumed quality of life of the patient, and the patient's medical condition than they are by advanced planning of care. In an attempt to understand the wishes of the patient doctors try to create the broadest possible basis for the decision making process and its outcome, mainly by involving the family.