LLukas22/scidocs huggingface dataset:
Pure shear horizontal SAW biosensor on langasite

The undetected introduction of pathogens into food or water supplies can produce grave consequences in terms of economic loss and human suffering. Sensitive and selective sensors capable of quickly detecting microbial pathogens are urgently needed to limit the effects of bioterrorist incidents, accidents, or pollution. Shear horizontal surface acoustic wave (SH SAW) devices provide an attractive platform for the design of microbial biosensors that function in liquid media, where Rayleigh-type modes are rapidly attenuated. This paper reports on an exploratory SH SAW delay line designed and fabricated on langasite, La/sub 3/Ga/sub 5/SiO/sub 14/ (LGS), along the novel Euler propagation direction (0/spl deg/, 22/spl deg/, 90/spl deg/). A liquid chamber was fabricated and attached to the top surface, and the device was submitted to liquid and biochemical tests. Moderate (6 dB) additional attenuation of the transmission coefficient, |S/sub 21/|, was consistently observed when the SH SAW delay line was assembled in the test fixture and submitted to the liquid tests, indicating that LGS is an attractive candidate for liquid sensing. Sensor selectivity can be achieved by integrating the LGS SH SAW delay line with a biochemical recognition layer. A test setup was implemented for the characterization of LGS SH SAW-based biosensors. The delay line response to biomolecule binding was shown by detection of sequential binding of proteins to the SH SAW device delay path. The biotinylated sensor was exposed sequentially to biotin-binding deglycosylated avidin, biotin-modified rabbit IgG, and goat anti-rabbit IgG antibody. As each protein was bound to the sensing surface, marked changes in the delay-line phase were recorded. The reported results demonstrate the capability of these devices to act as biochemical detectors in aqueous solutions, and this work represents the first effort using the novel material LGS in SAW-based biosensor technology.
A proposal on ACM organization

Dear Editor: Several ACM Members have suggested to me that the attached memorandum, originally offered to the ACM Council as an informal proposal and since, to the Commission of Thoughtful Persons for their consideration, be offered to the Letters section of communications, to make it available for the scrutiny of the ACM membership. Jack Moshman has remarked to me that the kind of organizational structure suggested here calls to mind of that of The American Statistical Association, and that it seems to work well for that organization. HERBERT S. BRIGHT Philco Corporation 3900 Welsh Road Willow Grove, Pa.
Grain legume pre-crops and their residues affect the growth, P uptake and size of P pools in the rhizosphere of the following wheat

Legumes have been shown to increase P uptake of the following cereal, but the underlying mechanisms are unclear. The aim of this study was to compare the effect of legume pre-crops and their residues on the growth, P uptake and size of soil P pools in the rhizosphere of the following wheat. Three grain legumes (faba bean, chickpea and white lupin) were grown until maturity in loamy sand soil with low P availability to which 80 mg P kg−1 was supplied. This pre-crop soil was then amended with legume residues or left un-amended and planted with wheat. The growth, P uptake and concentrations of P pools in the rhizosphere of the following wheat were measured 6 weeks after sowing. In a separate experiment, residue decomposition was measured over 42 days by determining soil CO2 release as well as available N and P. Decomposition rates were highest for chickpea residues and lowest for wheat residues. P release was greatest from white lupin residues and N release was greatest from faba bean residues, while wheat residues resulted in net N and P immobilisation. The growth of the following wheat was greater in legume pre-crop soil without residue than in soils with residue addition, while the reverse was true for plant P concentration. Among the legumes, faba bean had the strongest effect on growth, P uptake and concentrations of the rhizosphere P pools of the following wheat. Regardless of the pre-crop and residue treatment, wheat depleted the less labile pools residual P as well as NaOH-Pi and Po, with a stronger depletion of the organic pool. We conclude that although P in the added residues may become available during decomposition, the presence of the residues in the soil had a negative effect on the growth of the following wheat. Further, pre-crops or their residues had little effect on the size of P pools in the rhizosphere of wheat.
Fast Finite Shearlet Transform : a tutorial

3 Computation of the shearlet transform 13 3.1 Finite discrete shearlets . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14 3.2 A discrete shearlet frame . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16 3.3 Inversion of the shearlet transform . . . . . . . . . . . . . . . . . . . . . . . . . 20 3.4 Smooth shearlets . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 21 3.5 Implementation details . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26 3.5.1 Indexing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26 3.5.2 Computation of spectra . . . . . . . . . . . . . . . . . . . . . . . . . . . 27 3.6 Short documentation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 29 3.7 Download & Installation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30 3.8 Performance . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 31 3.9 Remarks . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32
Question Answering on Linked Data: Challenges and Future Directions

Question Answering (QA) systems are becoming the inspiring model for the future of search engines. While recently, underlying datasets for QA systems have been promoted from unstructured datasets to structured datasets with highly semantic-enriched metadata, but still question answering systems involve serious challenges which cause to be far beyond desired expectations. In this paper, we raise the challenges for building a Question Answering (QA) system especially with the focus of employing structured data (i.e. knowledge graph). This paper provide an exhaustive insight of the known challenges, so far. Thus, it helps researchers to easily spot open rooms for the future research agenda.
An integrated approach for planning the adoption of client/server systems

Abstract A large number of organizations are adopting the client/server technology. For an organization to benefit from the potential advantages of this technology such as reduced development time, improved employee productivity, and increased customer service satisfaction, the process of adoption and integration of client/server systems with existing legacy, mainframe-based systems should be carefully planned and implemented. In this paper, we consider two classes of applications, the first one consisting of applications that can run on either mainframes or client/server systems, but they are better suited for the latter, and the second one consisting of applications that are more appropriate to continue to be hosted by mainframes. In this paper, we present a model for the problem of developing a successful plan to integrate client/server and legacy systems under budget restrictions. A heuristic solution procedure based on a Lagrangean relaxation of the problem is developed. Extensive computational results across a variety of problem structures are reported. These results indicate that the solution procedure is quite effective for a wide range of problem instances.
The travelling salesperson problem with hotel selection

In this paper, we present the travelling salesperson problem with hotel selection (TSPHS), an extension of the TSP with a number of interesting applications. We present a mathematical formulation, explain the difference with related optimization problems and indicate what makes this problem inherently more difficult. We develop a simple but efficient heuristic that uses two constructive initialization procedures and an improvement procedure consisting of several neighbourhood search operators designed specifically for this problem, as well as some typical neighbourhoods from the literature. We generate several benchmark instances of varying sizes and compare the performance of our heuristic with CPLEX (10.0). We also generate some problems with known optimal solutions and use these to further demonstrate that our heuristic achieves good results in very limited computation times. Journal of the Operational Research Society (2012) 63, 207–217. doi:10.1057/jors.2011.18 Published online 14 September 2011
Intelligent stock trading system based on improved technical analysis and Echo State Network

Stock trading system to assist decision-making is an emerging research area and has great commercial potentials. Successful trading operations should occur near the reversal points of price trends. Traditional technical analysis, which usually appears as various trading rules, does aim to look for peaks and bottoms of trends and is widely used in stock market. Unfortunately, it is not convenient to directly apply technical analysis since it depends on person’s experience to select appropriate rules for individual share. In this paper, we enhance conventional technical analysis with Genetic Algorithms by learning trading rules from history for individual stock and then combine different rules together with Echo State Network to provide trading suggestions. Numerous experiments on S&P 500 components demonstrate that whether in bull or bear market, our system significantly outperforms buy-and-hold strategy. Especially in bear market where S&P 500 index declines a lot, our system still profits. 2011 Elsevier Ltd. All rights reserved.
Co-occurrence of Trichomonas vaginalis and bacterial vaginosis and vaginal shedding of HIV-1 RNA.

BACKGROUND
Trichomonas vaginalis (TV) and bacterial vaginosis (BV) are independently associated with increased risk of vaginal shedding in HIV-positive women. Because these 2 conditions commonly co-occur, this study was undertaken to examine the association between TV/BV co-occurrence and vaginal shedding of HIV-1 RNA.


METHODS
HIV-positive women attending outpatient HIV clinics in 3 urban US cities underwent a clinical examination; were screened for TV, BV, Neisseria gonorrhoeae, Chlamydia trachomatis, and vulvovaginal candidiasis; and completed a behavioral survey. Women shedding HIV-1 RNA vaginally (≥50 copies/mL) were compared with women who had an undetectable (<50 copies/mL) vaginal viral load to determine if women who were TV positive and BV positive or had co-occurrence of TV/BV had higher odds of shedding vaginally when compared with women who did not have these conditions.


RESULTS
In this sample of 373 HIV-positive women, 43.1% (n = 161) had co-occurrence of TV/BV and 33.2% (n = 124) were shedding HIV-1 RNA vaginally. The odds of shedding HIV vaginally in the presence of TV alone or BV alone and when TV/BV co-occurred were 4.07 (95% confidence interval [CI], 1.78-9.37), 5.65 (95% CI, 2.64-12.01), and 18.63 (95% CI, 6.71-51.72), respectively, when compared with women with no diagnosis of TV or BV, and after adjusting for age, antiretroviral therapy status, and plasma viral load.


CONCLUSIONS
T. vaginalis and BV were independently and synergistically related to vaginal shedding of HIV-1 RNA. Screening and prompt treatment of these 2 conditions among HIV-positive women are important not only clinically but for HIV prevention, as well.
Tea drinking is associated with benefits on bone density in older women.

BACKGROUND
Impaired hip structure assessed by dual-energy X-ray absorptiometry (DXA) areal bone mineral density (aBMD) is an independent predictor for osteoporotic hip fracture. Some studies suggest that tea intake may protect against bone loss.


OBJECTIVE
Using both cross-sectional and longitudinal study designs, we examined the relation of tea consumption with hip structure.


DESIGN
Randomly selected women (n = 1500) aged 70-85 y participated in a 5-y prospective trial to evaluate whether oral calcium supplements prevent osteoporotic fractures. aBMD at the hip was measured at years 1 and 5 with DXA. A cross-sectional analysis of 1027 of these women at 5 y assessed the relation of usual tea intake, measured by using a questionnaire, with aBMD. A prospective analysis of 164 women assessed the relation of tea intake at baseline, measured by using a 24-h dietary recall, with change in aBMD from years 1 to 5.


RESULTS
In the cross-sectional analysis, total hip aBMD was 2.8% greater in tea drinkers (x: 806; 95% CI: 797, 815 mg/cm(2)) than in non-tea drinkers (784; 764, 803 mg/cm(2)) (P < 0.05). In the prospective analysis over 4 y, tea drinkers lost an average of 1.6% of their total hip aBMD (-32; -45, -19 mg/cm(2)), but non-tea drinkers lost 4.0% (-13; -20, -5 mg/cm(2)) (P < 0.05). Adjustment for covariates did not influence the interpretation of results.


CONCLUSION
Tea drinking is associated with preservation of hip structure in elderly women. This finding provides further evidence of the beneficial effects of tea consumption on the skeleton.
Why software fails [software failure]

Most IT experts agree that software failures occur far more often than they should despite the fact that, for the most part, they are predictable and avoidable. It is unfortunate that most organizations don't see preventing failure as an urgent matter, even though that view risks harming the organization and maybe even destroying it. Because software failure has tremendous implications for business and society, it is important to understand why this attitude persists.
Effect of obesity on functional outcomes at 6 months post-stroke among elderly Koreans: a prospective multicentre study.

OBJECTIVES
We examined whether obesity based on body mass index (BMI) was a predictor of functional independence measure (FIM) at 6 months after ischaemic stroke onset while adjusting for stroke risk factors and covariates and stratifying by age group.


DESIGN
This is an interim report of the Korean Stroke Cohort for Functioning and Rehabilitation that was designed as a nested case study within a nationwide hospital-based cohort.


SETTING
We identified all patients who were admitted to nine representative hospitals in Korea from 2012 until 2014 under a diagnosis of acute first-ever ischaemic stroke. The hospitals were selected from the metropolitan district, mid-sized cities and a small-sized city.


PARTICIPANTS
The sample included 2057 patients with acute ischaemic stroke who were at least 18 years old.


PRIMARY AND SECONDARY OUTCOME MEASURES
We divided participants into two age levels (<65 and ≥ 65 years). Participants were classified into five groups according to their baseline BMI at admission: underweight (BMI<18.5), normal (18.5 ≤ BMI<23), overweight (23 ≤ BMI<25), obese (25 ≤ BMI<30) and extremely obese (30 ≤ BMI).


RESULTS
The proportion of patients who were aged ≥ 65 years was 55.0%. The proportions of underweight, normal, overweight, obese and extremely obese patients were 2.6%, 24.3%, 29.6%, 37.2% and 6.3%, respectively, in the <65 years group and 5.5%, 34.5%, 27.9%, 28.8% and 3.3%, respectively, in the ≥ 65 years group. In a multiple linear regression, the 6-month FIM after stroke in the elderly group was significantly associated with being extremely obese (7.95, p<0.05) after adjusting for confounding variables. In the <65 years group, the 6-month FIM was not associated with any weight category.


CONCLUSIONS
This nationwide hospital-based cohort study showed that extreme obesity is a predictor of a good 6-month FIM, especially in patients with ischaemic stroke who are at least 65 years of age.
Marginal mandibular nerve injury during neck dissection and its impact on patient perception of appearance.

BACKGROUND
Neck dissection to remove cervical lymph nodes is common practice in head and neck cancer management. The marginal mandibular nerve may be injured during neck dissection, particularly of level 1. The rate of injury to this nerve is underreported in the literature and its impact on patients is not well defined.


METHODS
An observational study was undertaken on patients who had undergone neck dissection over a 5-year period. The patients were examined for weakness and given a questionnaire related their perception of their appearance and their function.


RESULTS
Sixty-six patients were identified who had undergone 85 neck dissections. The rate of House Brackmann injury was 18% when analyzed by patient and 23% by neck. There were moderate correlations between observed injury and subjective responses to questions relating to ability to smile and weakness of the lower lip.


DISCUSSION
The rate of smile asymmetry following neck dissection is relatively high; however, severe injuries to the marginal mandibular nerve are uncommon.
The Role of Trust in Financial Customer-seller Relationships Before and After the Financial Crisis

This study examines the role of trust in customer–seller relationships before and after the 2008 financial crisis. On the basis of two surveys comprising 1155 and 757 bank customers, respectively, it is shown that trust is less likely to mediate the relationship between satisfaction and loyalty after the financial crisis compared with before the financial crisis. The results suggest that consumers rely more on satisfaction and less on trust after the financial crisis compared with before the financial crisis when determining whether they should remain loyal to a particular financial service provider. Hence, as a direct managerial implication, financial service managers should consider investing additional resources in satisfying their customers in the after crisis era. In addition, it is suggested that managers should seek to rebuild the positive relationship between trust and loyalty in order to receive the full benefit of their trust-building efforts. Copyright © 2014 John Wiley & Sons, Ltd.
In vitro antibacterial activity of aminosterols against multidrug-resistant bacteria from patients with cystic fibrosis.

OBJECTIVES
Respiratory infections with multidrug-resistant (MDR) bacteria are life-threatening in patients with cystic fibrosis (CF). Squalamine and aminosterol derivatives (ASDs) have previously demonstrated interesting antibacterial activity against bacterial reference strains. This study investigated for the first time their activity against MDR clinical isolates recovered from the sputa of CF patients.


METHODS
Antibacterial activity of squalamine and two ASDs (1 and 2) was evaluated against 135 MDR gram-negative and gram-positive bacteria using the broth microdilution method for MIC determination.


RESULTS
For gram-negative bacteria, MICs ranged from 2 to 128 mg/L. Resistance to colistin and mucoidity were significantly associated with higher MICs of squalamine and ASDs 1 and 2. Tested compounds were active against various gram-positive bacteria with MIC values varying from 0.5 to 8 mg/L, with the exception of two capsulated isolates of Streptococcus pneumoniae demonstrating MICs of 32 mg/L.


CONCLUSIONS
In this study, we present new findings concerning the antibacterial potential of ASDs against MDR bacteria. Colistin-resistant, mucoid and capsulated bacteria were found to exhibit decreased susceptibility to ASDs indicating that these compounds might share some mechanistic aspects with polymyxins towards gram-negative bacteria. However, ASDs were remarkably active against gram-positive species suggesting different mechanisms of action towards gram-positive and gram-negative bacteria. As tested ASDs exhibited elevated MICs in some cases, we believe that these compounds may be developed to be locally administrated as aerosols rather than via systemic administration routes. Further work is warranted to evaluate their in vivo efficacy in aerosol formulations using a lung-infected animal model.
Enhanced gradient-based algorithm for the estimation of fingerprint orientation fields

An accurate estimation of fingerprint orientation fields is an essential step in the overall fingerprint recognition process. Conventional gradient-based approaches are popular but very sensitive to noise. In this paper, we propose a novel implementation to improve the performance of gradient-based methods. The enhanced algorithm chooses the best orientation estimate from four overlapping neighborhoods of every image block, where the voting scheme is based on the reliability measures. We test our algorithm on real fingerprint images. The experiment results suggest that our enhanced algorithm achieves visibly better noise resistance with modest computation time in comparison with other gradient-based methods. 2006 Elsevier Inc. All rights reserved.
The Go-Go Interaction Technique: Non-Linear Mapping for Direct Manipulation in VR

The Go-Go immersive interaction technique uses the metaphor of interactively growing the user’s arm and non-linear mapping for reaching and manipulating distant objects. Unlike others, our technique allows for seamless direct manipulation of both nearby objects and those at a distance.
Association between major depressive disorder and heart rate variability in the Netherlands Study of Depression and Anxiety (NESDA).

CONTEXT
It has been hypothesized that depression is associated with lower heart rate variability and decreased cardiac vagal control. This may play an important role in the risk of cardiovascular disease among depressed individuals.


OBJECTIVE
To determine whether heart rate variability was lower in depressed individuals than in healthy controls in a large adult sample.


DESIGN
Cross-sectional analyses from a large depression cohort study.


SETTING
The Netherlands Study of Depression and Anxiety.


PARTICIPANTS
Two thousand three hundred seventy-three individuals (mean age, 41.8 years; 66.8% female) who participated in the Netherlands Study of Depression and Anxiety. Included were 524 controls, 774 individuals with a diagnosis of major depressive disorder (MDD) earlier in life (remitted MDD), and 1075 individuals with current MDD based on the Composite International Diagnostic Interview. This sample was sufficiently powered to examine the confounding effects of lifestyle, comorbid anxiety, and antidepressants.


MAIN OUTCOME MEASURES
The standard deviation of normal-to-normal beats (SDNN) and cardiac vagal control, as indexed by respiratory sinus arrhythmia (RSA), were measured during 1(1/2) hours of ambulatory recording of electrocardiograms and thorax impedance. Multivariate analyses were conducted to compare SDNN and RSA across depression groups after adjustment for demographics, health, lifestyle, comorbid anxiety, and psychoactive medication.


RESULTS
Individuals with remitted and current MDD had a lower mean SDNN and RSA compared with controls (SDNN, 3.1-5.7 milliseconds shorter, P < or = .02; RSA, 5.1-7.1 milliseconds shorter, P < .001; effect size, 0.125-0.269). Comorbid anxiety and lifestyle did not reduce these associations. However, accounting for psychoactive medication removed the association with SDNN and strongly attenuated the association with RSA. Depressed individuals who were using selective serotonin reuptake inhibitors, tricyclic antidepressants, or other antidepressants had significantly shorter SDNNs and RSAs (effect size, 0.207-0.862) compared with controls and depressed individuals not taking medication.


CONCLUSIONS
This study shows that depression is associated with significantly lowered heart rate variability. However, this association appears to be mainly driven by the effect of antidepressants.