LLukas22/scidocs huggingface dataset:
Testing Snort with SQL Injection Attacks

Currently, information security is a significant challenge in the information era because businesses store critical information in databases. Therefore, databases need to be a secure component of an enterprise. Organizations use Intrusion Detection Systems (IDS) as a security infrastructure component, of which a popular implementation is Snort. In this paper, we provide an overview of Snort and evaluate its ability to detect SQL Injection attacks.
Tumor infiltrated hilar and mediastinal lymph nodes are an independent prognostic factor for decreased survival after pulmonary metastasectomy in patients with renal cell carcinoma.

PURPOSE
Surgical resection remains the most effective treatment in patients with pulmonary metastasis of renal cell carcinoma. To our knowledge the prognostic significance of mediastinal and hilar lymph node metastasis during pulmonary metastasectomy in patients with renal cell carcinoma is unknown. We analyzed the value of computerized tomography to predict mediastinal/hilar lymph node involvement as well as the impact of systematic lymphadenectomy on survival in patients with pulmonary renal cell carcinoma metastasis.


MATERIALS AND METHODS
We analyzed survival in 110 patients who underwent resection of pulmonary metastasis of renal cell carcinoma using the Kaplan-Meier method. Multivariate analysis was done by Cox regression analysis.


RESULTS
Lymph node metastasis was histologically proved in 35% of patients. Metastasis was not associated with initial tumor grade, lymph node status, the number of pulmonary metastases or recurrent pulmonary metastasis. Computerized tomography had 84% sensitivity and 97% specificity to predict lymph node metastasis. Sensitivity was markedly better for detecting mediastinal than hilar lymph node metastasis (90% vs 69%). Patients with lymph node metastasis had significantly shorter median survival than patients without lymph node metastasis (19 vs 102 months, p <0.001). Multivariate analysis revealed that tumor infiltrated mediastinal lymph nodes were an independent prognostic factor for patient survival. Match paired analysis showed that after lymph node dissection patients showed a trend toward improved survival.


CONCLUSIONS
Mediastinal and hilar lymph node metastases significantly correlate with decreased survival. Systematic lymphadenectomy provides valuable information on staging and prognosis in patients with pulmonary metastasis of renal cell carcinoma, and may prolong survival.
A novel enzyme-linked immunosorbent assay for detection of Escherichia coli O157:H7 using immunomagnetic and beacon gold nanoparticles

This paper presents a functional nanoparticle-enhanced enzyme-linked immunosorbent assay (FNP-ELISA) for detection of enterohemorrhagic Escherichia coli (EHEC) O157:H7. Immunomagnetic nanoparticles (IMMPs) conjugated with monoclonal anti-O157:H7 antibody were used to capture E. coli O157:H7. Beacon gold nanoparticles (B-GNPs) coated with polyclonal anti-O157:H7 and biotin single-stranded DNA (B-DNA) were then subjective to immunoreaction with E. coli O157:H7, which was followed by streptavidin-horseradish peroxidase (Strep-HRP) conjugated with B-GNPs based on a biotin-avidin system. The solutions containing E. coli O157:H7, IMMPs, B-GNPs, and Strep-HRP were collected for detecting color change. The signal was significantly amplified with detection limits of 68 CFU mL(-1) in PBS and 6.8 × 10(2) to 6.8 × 10(3) CFU mL(-1) in the food samples. The FNP-ELISA method developed in this study was two orders of magnitude more sensitive than immunomagnetic separation ELISA (IMS-ELISA) and four orders of magnitude more sensitive than C-ELISA. The entire detection process of E. coli O157:H7 lasted only 3 h, and thus FNP-ELISA is considered as a time-saving method.
Selective activation of the infraspinatus muscle.

CONTEXT
To improve selective infraspinatus muscle strength and endurance, researchers have recommended selective shoulder external-rotation exercise during rehabilitation or athletic conditioning programs. Although selective strengthening of the infraspinatus muscle is recommended for therapy and training, limited information is available to help clinicians design a selective strengthening program.


OBJECTIVE
To determine the most effective of 4 shoulder external-rotation exercises for selectively stimulating infraspinatus muscle activity while minimizing the use of the middle trapezius and posterior deltoid muscles.


DESIGN
Cross-sectional study.


SETTING
University research laboratory.


PATIENTS OR OTHER PARTICIPANTS
A total of 30 healthy participants (24 men, 6 women; age = 22.6 ± 1.7 years, height = 176.2 ± 4.5 cm, mass = 65.6 ± 7.4 kg) from a university population.


INTERVENTION(S)
The participants were instructed to perform 4 exercises: (1) prone horizontal abduction with external rotation (PER), (2) side-lying wiper exercise (SWE), (3) side-lying external rotation (SER), and (4) standing external-rotation exercise (STER).


MAIN OUTCOME MEASURE(S)
Surface electromyography signals were recorded from the infraspinatus, middle trapezius, and posterior deltoid muscles. Differences among the exercise positions were tested using a 1-way repeated-measures analysis of variance with Bonferroni adjustment.


RESULTS
The infraspinatus muscle activity was greater in the SWE (55.98% ± 18.79%) than in the PER (46.14% ± 15.65%), SER (43.38% ± 22.26%), and STER (26.11% ± 15.00%) (F3,87 = 19.97, P < .001). Furthermore, the SWE elicited the least amount of activity in the middle trapezius muscle (F3,87 = 20.15, P < .001). Posterior deltoid muscle activity was similar in the SWE and SER but less than that measured in the PER and STER (F3,87 = 25.10, P < .001).


CONCLUSIONS
The SWE was superior to the PER, SER, and STER in maximizing infraspinatus activity with the least amount of middle trapezius and posterior deltoid activity. These findings may help clinicians design effective exercise programs.
Immunolocalization of extracellular matrix components during organogenesis in the human small intestine

The expression and distribution of several major extracellular matrix macromolecules were investigated at the epithelial-mesenchymal interface of the human fetal small intestine from 8 to 20 weeks of gestation. Localization of heparan sulfate proteoglycan, type-IV collagen and laminin, three basement membrane components, as well as fibronectin and tenascin, were assessed by indirect immunofluorescence staining on cryostat sections, and correlated to morphogenesis and epithelial cell differentiation. Basement membrane components and fibronectin were all detected as early as 8 weeks (a time when the epithelium is still stratified and does not express sucrase-isomaltase). Tenascin appeared only after short villi had developed (around 10 weeks) and was restricted to the connective tissue at the tip of villus rudiments. At 18 weeks, well-formed villi and crypts were apparent. The antibody against heparan sulfate proteoglycan stained exclusively the epithelial basement membrane. Anti-type-IV collagen and anti-laminin anti-bodies stained the epithelial basement membrane and also cellular and fibrillar structures in the lamina propria. Fibronectin was found uniformly distributed over the lamina propria except in the upper third position of the villus core. On the contrary tenascin was mainly localized in the stroma at the tip of the villi. Staining for tenascin was also detected at the epithelial-mesenchymal interface of the villus and in the mesenchyme immediately surrounding budding crypts. These results provide basic data concerning the development of the human gut, and suggest that extracellular matrix components could be involved in the remodelling process of the intestinal mucosa.
Long-range pure magnon spin diffusion observed in a nonlocal spin-Seebeck geometry

Brandon L. Giles1, Zihao Yang2, John S. Jamison1, and Roberto C. Myers1-3 1Department of Materials Science and Engineering, The Ohio State University, Columbus, OH, 43210, USA Email: myers.1079@osu.edu , Web site: http://myersgroup.engineering.osu.edu 2Department of Electrical and Computer Engineering, The Ohio State University, Columbus, OH, 43210, USA 3 Department of Physics, The Ohio State University, Columbus, OH, USA
The effects of strength training on central arterial compliance in middle-aged and older adults.

BACKGROUND
Contrary to aerobic exercise, strength training (ST) is associated with decreased central arterial compliance in young men. It is unknown whether ST, with or without concurrent endurance training, would have a similar effect in older adults with reduced baseline arterial compliance.


OBJECTIVE
The primary aim of this study was to determine the effect of a ST program on central arterial compliance in middle-aged and older adults.


DESIGN
Randomized, controlled intervention study in which 37 healthy, sedentary men and women (52+/-2 years) performed 13 weeks of ST (n=13), ST+aerobic exercise (n=12) or stretching exercises as a control group (n=12).


METHODS
Participants were rigorously screened for cardiovascular disease and underwent pre-post testing for carotid arterial compliance (via simultaneous ultrasound and applanation tonometry), carotid-femoral pulse wave velocity, plasma endothelin-1 and angiotensin II concentrations and carotid artery vasoreactivity (cold pressor test).


RESULTS
ST performed alone, or in conjunction with aerobic exercise, improved maximal muscle strength and increased total lean body mass (both P<0.01). No significant changes were observed in carotid artery compliance or carotid-femoral pulse wave velocity following ST or ST+aerobic exercise. Carotid artery compliance increased significantly (23%) following stretching which may be attributed to a reduction in carotid pulse pressure. No significant changes were observed in plasma vasoconstrictor hormones or carotid artery vasoreactivity following the interventions.


CONCLUSION
Thirteen weeks of moderate ST two or three times per week does not reduce central arterial compliance in middle-aged and older adults.
Affective Neuroscience : Past , Present , and Future

The advent of modern neuroscience methodologies has led to an explosion over the past 15 years in our understanding of brain regions involved in the recognition, generation, experience, and regulation of emotion. In this brief review, we suggest some early historical milestones in the development of what has become known as affective neuroscience, and then consider the extent to which recent findings have advanced understanding in the field (see Table 1). We begin with the pioneering work of James and Lange, go on discuss the early functional neuroanatomical models of Cannon and Bard, then outline the hypothalamic stimulation studies conducted by Hess, and finally, consider Papez and MacLean’s development of increasingly sophisticated neuroanatomical frameworks. We evaluate how well these key contributions fit with the current state of knowledge about which brain regions are seemingly central to the representation and processing of affect, including the amygdala, prefrontal cortex, thalamus, insular, anterior cingulate cortex, and midbrain. We next very briefly overview contemporary theoretical frameworks of how these regions might interact. Finally, we offer some thoughts about possible future directions for affective neuroscience.1
The serotonin transporter gene polymorphism 5-HTTLPR moderates the effects of stress on attention-deficit/hyperactivity disorder.

INTRODUCTION
The role of the serotonin transporter gene polymorphism 5-HTTLPR in attention-deficit/hyperactivity disorder (ADHD) is unclear. Heterogeneity of findings may be explained by gene-environment interactions (GxE), as it has been suggested that S-allele carriers are more reactive to psychosocial stress than L-allele homozygotes. This study aimed to investigate whether 5-HTTLPR genotype moderates the effects of stress on ADHD in a multisite prospective ADHD cohort study.


METHODS
5-HTTLPR genotype, as well as the number of stressful life events in the past 5 years and ongoing long-term difficulties, was determined in 671 adolescents and young adults with ADHD, their siblings, and healthy controls (57.4% male, average age 17.3 years). Linear mixed models, accounting for family relatedness, were applied to investigate the effects of genotype, experienced stress, and their interaction on ADHD severity at time point T2, while controlling for ADHD severity at T1 (mean follow-up time 5.9 years) and for comorbid internalizing problems at T2.


RESULTS
The interaction between genotype and stress significantly predicted ADHD severity at T2 (p = .006), which was driven by the effect on hyperactivity-impulsivity (p = .004). Probing of the interaction effect made clear that S-allele carriers had a significantly more positive correlation between stress and ADHD severity than L-allele homozygotes.


CONCLUSION
The results show that the interaction between 5-HTTLPR and stress is a mechanism involved particularly in the hyperactivity/impulsivity dimension of ADHD, and that this is independent of comorbid internalizing problems. Further research into the neurobiological mechanisms underlying this interaction effect is warranted.
Improving document clustering using Okapi BM25 feature weighting

We investigate the effect of feature weighting on document clustering, including a novel investigation of Okapi BM25 feature weighting. Using eight document datasets and 17 well-established clustering algorithms we show that the benefit of tf-idf weighting over tf weighting is heavily dependent on both the dataset being clustered and the algorithm used. In addition, binary weighting is shown to be consistently inferior to both tf-idf weighting and tf weighting. We investigate clustering using both BM25 term saturation in isolation and BM25 term saturation with idf, confirming that both are superior to their non-BM25 counterparts under several common clustering quality measures. Finally, we investigate estimation of the k1 BM25 parameter when clustering. Our results indicate that typical values of k1 from other IR tasks are not appropriate for clustering; k1 needs to be higher.
Automated Model Acquisition from Range Images with View Planning

We present an incremental system that builds accura CAD models of objects from multiple range images. Usin a hybrid of surface mesh and volumetric representation the system creates a “water-tight” 3D model at each step the modeling process, allowing reasonable models to built from a small number of views. We also present method that can be used to plan the next view and reduce number of scans needed to recover the object. Results presented for the creation of 3D models of a computer gam controller, a hip joint prosthesis, and a mechanical strut.
Hair Tourniquet Syndrome of Labia Minora

We present two uncommon cases of adolescent girls with hair-thread strangulation of the labia minora. The first 14-year-old girl presented with a painful pedunculated labial lump (Fig. 1). The lesion was covered with exudate. She was examined under sedation and found a coil of long hair forming a tourniquet around a labial segment. Thread removal resulted to immediate relief from pain, and gradual return to normal appearance. Another 10-year-old girl presented with a similar labial swelling. The recent experience of the first case led us straight to the problem. A long hair-thread was found at the neck of the lesion. Hair removal resulted in settling of the pain. The labial swelling subsided in few days.
When Customers Get Clever: Managerial Approaches to Dealing With Creative Consumers

Creative consumers (defined as customers who adapt, modify, or transform a proprietary offering) represent an intriguing paradox for business. On one hand, they can signify a black hole for future revenue, with breach of copyright and intellectual property. On the other hand, they represent a gold mine of ideas and business opportunities. Central to business is the need to create and capture value, and creative consumers demand a shift in the mindsets and business models of how firms accomplish both. Based upon their attitude and action toward customer innovation, we develop a typology of firms’ stances toward creative consumers. We then consider the implications of the stances model for corporate strategy and examine a three-step approach to dealing with creative consumers: awareness, analysis, and response. D 2006 Kelley School of Business, Indiana University. All rights reserved. 1. When customers get clever What happens when customers get clever? What should a firm do when creative consumers start to modify products, hack code, and adjust services to suit themselves? The following examples illustrate the dilemmas managers face, and the very different strategies firms employ in dealing with the phenomenon: ! Podcasting is the distribution of audio or video files, such as radio programs or music videos, over the Internet for listening on mobile devices and personal computers. While the idea had been around since the year 2000, podcasting really took off with the 2001 advent of Apple’s ubiquitous iPod. Yet, Apple was notoriously slow in capitalizing on the phenomenon, perhaps fearful of the copyright and digital property implications of its devices being used to store and play content. It was not until mid2005 that Apple began to include podcasting software with its iPod products or make podcasts available on its iTunes website. To many iPod owners (and to fans of podcasting), it seemed that Apple had, at first, discouraged podcasting. At the very least, the company declined to comment on it in the early days of the phenomenon. 0007-6813/$ see front matter D 2006 Kelley School of Business, Indiana University. All rights reserved. doi:10.1016/j.bushor.2006.05.005 * Corresponding author. E-mail address: lpitt@sfu.edu (L.F. Pitt). KEYWORDS
Work-related Mental Consequences: Implications of Burnout on Mental Health Status Among Health Care Providers

INTRODUCTION
Burnout can create problems in every aspect of individual's' human life. It may have an adverse effect on interpersonal and family relations and can lead to a general negative attitude towards life.


AIM
The purpose of this study is to investigate whether burnout is associated with the mental health status of health care providers.


MATERIAL AND METHODS
The sample in this study consisted of 240 health care employees. The Greek version of Maslach's Burnout Inventory (MBI) was used for measuring burnout levels and the Greek version of the Symptoms Rating Scale for Depression and Anxiety (SRSDA) questionnaire was used to evaluate health care providers' mental health status. Descriptive statistics were initially generated for sample characteristics. Normality was checked by the Kolmogorov-Smirnov test and data was processed with parametric tests. General linear models with MBI dimensions as independent variables and SRSDA subscales as dependent variables were used to determine the relation between burnout and mental health status. Statistics were processed with SPSS v. 17.0 (SPSS, Chicago, IL, USA). Statistical significance was set at p=0.05.


RESULTS
The average age of the sample is 40.00±7.95 years. Regarding gender the percentage of men is 21.40% (N=49) and of women is 78.60% (N=180). Overall the professional burnout of health care workers is moderate. The mean score for emotional exhaustion is 26.41, for personal accomplishment 36.70 and for depersonalization 9.81. The mean for each subscale of SRSDA is 8.23±6.79 for Depression Beck-21, 3.96±4.26 for Depression Beck-13, 4.91±4.44 for Melancholia, 6.32±4.35 for Asthenia and 6.36±4.72 for Anxiety. The results of general linear models with the MBI dimensions as independent variables and the SRSDA subscales as dependent variables are shown that emotional exhaustion and personal accomplishment are statistically correlated with all subscales of SRSDA, while depersonalization is not correlated with any SRSDA subscale.


CONCLUSIONS
Burnout appears to implicate mental health status of healthcare providers in work index. Emotional exhaustion is the burnout dimension that is correlated the most with employees' mental health.
Effects of switching from prandial premixed insulin therapy to basal plus two times bolus insulin therapy on glycemic control and quality of life in patients with type 2 diabetes mellitus

BACKGROUND
The effects of switching from prandial premixed insulin therapy (PPT) injected three times a day to basal plus two times bolus insulin therapy (B2B) on glycemic control and quality of life were investigated in patients with type 2 diabetes mellitus.


METHODS
The clinical course was prospectively observed during the first 16 weeks after switching to B2B (insulin glargine plus insulin glulisine before breakfast and dinner) in 27 subjects previously treated with PPT using 50/50 premixed insulin. The Diabetes Treatment Satisfaction Questionnaire (DTSQ) was administered at the start and end of the study.


RESULTS
The glycated hemoglobin (HbA1c) level (8.3% ± 1.8% to 8.2% ± 1.1%) and the DTSQ score did not change between the start and end of the study. An improvement in HbA1c level was found in nine (33%) subjects. The change in HbA1c showed a significant negative correlation with baseline HbA1c, and was significantly better in patients with a baseline HbA1c >8.0% than in those with an HbA1c ≤ 8.0% (-0.9 ± 2.0 versus 0.3 ± 0.6, respectively, P = 0.02). The change in DTSQ score representing treatment satisfaction was significantly greater in patients whose HbA1c level was improved than in those in whom it was not (2.7 ± 3.6 versus -0.8 ± 3.5, P = 0.04).


CONCLUSION
B2B was noninferior to PPT with regard to HbA1c levels in patients with type 2 diabetes mellitus. B2B should be considered particularly for subjects whose glycemic control is poor despite PPT.
Predicting Mortality in Non-Variceal Upper Gastrointestinal Bleeders: Validation of the Italian PNED Score and Prospective Comparison With the Rockall Score

OBJECTIVES:We sought (i) to validate a new prediction rule of mortality (Progetto Nazionale Emorragia Digestiva (PNED) score) on an independent population with non-variceal upper gastrointestinal bleeding (UGIB) and (ii) to compare the accuracy of the Italian PNED score vs. the Rockall score in predicting the risk of death.METHODS:We conducted prospective validation of analysis of consecutive patients with UGIB at 21 hospitals from 2007 to 2008. Outcome measure was 30-day mortality. All the variables used to calculate the Rockall score as well as those identified in the Italian predictive model were considered. Calibration of the model was tested using the χ2 goodness-of-fit and performance characteristics with receiver operating characteristic (ROC) analysis. The area under the ROC curve (AUC) was used to quantify the diagnostic accuracy of the two predictive models.RESULTS:Over a 16-month period, data on 1,360 patients were entered in a national database and analyzed. Peptic ulcer bleeding was recorded in 60.7% of cases. One or more comorbidities were present in 66% of patients. Endoscopic treatment was delivered in all high-risk patients followed by high-dose intravenous proton pump inhibitor in 95% of them. Sixty-six patients died (mortality 4.85%; 3.54–5.75). The PNED score showed a high discriminant capability and was significantly superior to the Rockall score in predicting the risk of death (AUC 0.81 (0.72–0.90) vs. 0.66 (0.60–0.72), P<0.000). Positive likelihood ratio for mortality in patients with a PNED risk score >8 was 16.05.CONCLUSIONS:The Italian 10-point score for the prediction of death was successfully validated in this independent population of patients with non-variceal gastrointestinal bleeding. The PNED score is accurate and superior to the Rockall score. Further external validation at the international level is needed.