LLukas22/scidocs huggingface dataset:
Consumer Trust in an Internet Store: A Cross-Cultural Validation

© 1999 International Communication Association Issue Section: Original Article Download all figures Many have speculated that trust plays a critical role in stimulating consumer purchases over the Internet. Most of the speculations have rallied around U.S. consumers purchasing from U.S.–based online merchants. The global nature of the Internet raises questions about the robustness of trust effects across cultures. Culture may also affect the antecedents of consumer trust; that is, consumers in different cultures might have differing expectations of what makes a web merchant trustworthy. Here we report on a cross-cultural validation of an Internet consumer trust model. The model examined both antecedents and consequences of consumer trust in a Web merchant. The results provide tentative support for the generalizability of the model. Article activity alert Receive exclusive of f ers and updates f rom Oxf ord Academic
CD4+ and CD8+ T-cell immunity to Dengue - lessons for the study of Zika virus.

Dengue virus (DENV) and Zika virus (ZIKV) are rapidly emerging mosquito-borne flaviviruses that represent a public health concern. Understanding host protective immunity to these viruses is critical for the design of optimal vaccines. Over a decade of research has highlighted a significant contribution of the T-cell response to both protection and/or disease enhancement during DENV infection, the latter being mainly associated with sub-optimal cross-reactive T-cell responses during secondary infections. Phase IIb/III clinical trials of the first licensed tetravalent dengue vaccine highlight increased vaccine efficacy in dengue-immune as opposed to dengue-naive vaccinees, suggesting a possible immunoprotective role of pre-existing DENV-specific T cells that are boosted upon vaccination. No vaccine is available for ZIKV and little is known about the T-cell response to this virus. ZIKV and DENV are closely related viruses with a sequence identity ranging from 44% and 56% for the structural proteins capsid and envelope to 68% for the more conserved non-structural proteins NS3/NS5, which represent the main targets of the CD4+ and CD8+ T-cell response to DENV, respectively. In this review we discuss our current knowledge of T-cell immunity to DENV and what it can teach us for the study of ZIKV. The extent of T-cell cross-reactivity towards ZIKV of pre-existing DENV-specific memory T cells and its potential impact on protective immunity and/or immunopathology will also be discussed.
Applying Cloud Computing Technology to BIM Visualization and Manipulation

A current trend in the construction sector is the application of Building Information Modeling (BIM) for the efficient integration and management of engineering information. Today, engineering consultant, construction and architectural companies conduct research into the development of BIM in order to integrate and visualize engineering information. The capabilities of BIM for information integration, visualization and parametric design, reduce duplication of work and interface integration complexity, significantly saving both time and cost. At present, BIM desktop applications such as Autodesk Architecture, Bentley Architecture and Graphsoft ArchiCAD, can only integrate and visualize information on-site. Difficulties remain in obtaining and updating information from other sites, which restricts communication and information distribution between different sites. As visualization efficiencies and hardware capabilities mature and continue to improve, the development framework of applications is now moving form “Client-Server” to “Host-based”, which is referred to as “Cloud Computing” technology. In this research, we utilize the concept of Software as a Service (SaaS) and Cloud Computing in order to develop a visual system for BIM visualization and manipulation. This system can not only visualize three-dimensional (3D) BIM models, it can also manipulate 3D BIM models through the web without the limitations of time or distance. This system can facilitate communication and distribution of information between related participants, such as construction companies, building owners and architectural companies in order to manage projects effectively and efficiently.
Mean heart dose variation over a course of breath-holding breast cancer radiotherapy

OBJECTIVE
The purpose of the work was to estimate the dose received by the heart throughout a course of breath-holding breast radiotherapy.


METHODS
113 cone-beam CT (CBCT) scans were acquired for 20 patients treated within the HeartSpare 1A study, in which both an active breathing control (ABC) device and a voluntary breath-hold (VBH) method were used. Predicted mean heart doses were obtained from treatment plans. CBCT scans were imported into a treatment planning system, heart outlines defined, images registered to the CT planning scan and mean heart dose recorded. Two observers outlined two cases three times each to assess interobserver and intraobserver variation.


RESULTS
There were no statistically significant differences between ABC and VBH heart dose data from CT planning scans, or in the CBCT-based estimates of heart dose, and no effect from the order of the breath-hold method. Variation in mean heart dose per fraction over the three imaged fractions was <6 cGy without setup correction, decreasing to 3.3 cGy with setup correction. If scaled to 15 fractions, all differences between predicted and estimated mean heart doses were <0.5 Gy and in 80% of cases, they were <0.25 Gy.


CONCLUSION
Variation in mean heart dose was at an acceptable level over the duration of breath-holding radiotherapy and was well predicted by the planning system. Advances in knowledge: Mean heart dose was not adversely affected by fraction-to-fraction variations throughout a course of heart-sparing radiotherapy using two well-established breath-holding methods.
Physical Performance Is Associated with Working Memory in Older People with Mild to Severe Cognitive Impairment

BACKGROUND
Physical performances and cognition are positively related in cognitively healthy people. The aim of this study was to examine whether physical performances are related to specific cognitive functioning in older people with mild to severe cognitive impairment.


METHODS
This cross-sectional study included 134 people with a mild to severe cognitive impairment (mean age 82 years). Multiple linear regression was performed, after controlling for covariates and the level of global cognition, with the performances on mobility, strength, aerobic fitness, and balance as predictors and working memory and episodic memory as dependent variables.


RESULTS
The full models explain 49-57% of the variance in working memory and 40-43% of episodic memory. Strength, aerobic fitness, and balance are significantly associated with working memory, explaining 3-7% of its variance, irrespective of the severity of the cognitive impairment. Physical performance is not related to episodic memory in older people with mild to severe cognitive impairment.


CONCLUSIONS
Physical performance is associated with working memory in older people with cognitive impairment. Future studies should investigate whether physical exercise for increased physical performance can improve cognitive functioning. This trial is registered with ClinicalTrials.gov NTR1482.
Antihistamine: A Useful Medication with Minimal Adverse Drug Reactions to Improve Acne Symptoms and Reduce Sebum Production

Background: Acne vulgaris is a common skin disease that affects not only teenagers but also the general population. Although acne is not physically disabling, its psychological impact can be striking, contributing to low self-esteem, depression, and anxiety. As a result, there is a significant demand for effective acne therapies. Antihistamine is a widely used medication to treat several allergic skin conditions and yet it also has been found to decrease complications of acne and improve acne symptoms. For the severe cystic acne vulgaris, oral retinoids such as isotretinoin is the primary treatment; however, health care providers hesitate to prescribe isotretinoin due to its adverse drug reactions. On the other hand, antihistamine is well known by its safe and minimal side effects. Can an antihistamine intervention in standardized treatment of acne vulgaris significantly impact the improvement of acne symptoms and reduce sebum production? Methods: An exhaustive search was conducted by MEDLINE-OVID, CINAHL, UptoDate, Web of Science, Google scholar, MEDLINE-PubMed, Clinicalkey, and ProQuest by using keywords: acne vulgaris and antihistamine. Relevant articles were assessed for quality using GRADE. Results: After the exhaustive search, two studies met the inclusion criteria and eligibility criteria. Effect of antihistamine as an adjuvant treatment of isotretinoin in acne:a randomized, controlled comparative study contains the comparison of 20 patients with moderate acne are treated with isotretinoin and another 20 patients with moderate acne are treated with additional antihistamine. Identification of Histamine Receptors and Reduction of Squalene Levels by an Antihistamine in Sebocytes was conducted on human tissue to verify the decrease of sebum production by the antihistamine’s effect. Conclusion: Both studies demonstrate the usefulness of an histamine antagonist in reducing sebum production and improving acne symptoms. Due to its low cost and safety, a recommendation can be made for antihistamine to treat acne vulgaris as an adjuvant therapy to standardized treatment. Degree Type Capstone Project Degree Name Master of Science in Physician Assistant Studies First Advisor David Keene PA-C
DSM-5 and autism spectrum disorders (ASDs): an opportunity for identifying ASD subtypes

The heterogeneous clinical presentations of individuals with autism spectrum disorders (ASDs) poses a significant challenge for sample characterization and limits the interpretability and replicability of research studies. The Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5) diagnostic criteria for ASD, with its dimensional approach, may be a useful framework to increase the homogeneity of research samples. In this review, we summarize the revisions to the diagnostic criteria for ASD, briefly highlight the literature supporting these changes, and illustrate how DSM-5 can improve sample characterization and provide opportunities for researchers to identify possible subtypes within ASD.
Detection of cytomegalovirus in upper gastrointestinal biopsies from heart transplant recipients: comparison of light microscopy, immunocytochemistry, in situ hybridisation, and nested PCR.

AIM
To establish the diagnostic value of in situ hybridisation and the nested polymerase chain reaction (PCR) in detecting clinically relevant cytomegalovirus (CMV) infection in upper gastrointestinal biopsies from heart transplant patients.


METHODS
Test sensitivity and specificity for detection of CMV early gene RNA by in situ hybridisation and CMV intermediate early gene by PCR were established and then compared with haematoxylin and eosin (H&E) and immunocytochemical detection of CMV in order to establish the best pathological diagnostic approach. All investigations were carried out on formalin fixed, paraffin embedded tissue.


RESULTS
Nested PCR had the highest test sensitivity, followed by in situ hybridisation and immunocytochemistry with the same sensitivity; H&E had the lowest. H&E and immunocytochemistry were the most specific but both had a significant false negative rate which was less of a problem with PCR. However, PCR gave no other diagnostic information, and in situ hybridisation was no better than immunocytochemistry. Both in situ hybridisation and PCR were technically complex and more expensive.


CONCLUSIONS
H&E and immunocytochemistry represent the best initial screen for CMV and other diseases in upper gastrointestinal biopsies from heart transplant patients. If H&E and immunocytochemistry were negative, nested PCR could significantly increase the diagnostic yield of clinically relevant CMV infection. In situ hybridisation appeared to have no advantages and some drawbacks compared with immunocytochemistry and PCR.
Design Principles for Machining System Configurations

Until recently, mass producers have relied on long serial lines of dedicated machines in order to machine products at high volumes. Today, as the cost of CNC machining centers decreases, more and more highvolume manufacturers are examining the alternative of shorter lines with more machines configured in parallel. This paper presents the main principles for selecting the right machining system configurations. We propose a system classification and show that only symmetric configurations are of interest to industry. We compare four classes of systems: pure serial lines, pure parallel lines, short serial lines arranged in parallel, and short serial lines arranged in parallel with the ability to move products between the lines (i.e., with crossover). Specifically, we compare the different configurations in terms of throughput, line balancing, machine investment cost, and capacity scalability. Finally, we introduce an upgradable multi-spindle reconfigurable machine as a costeffective alternative for system scalability.
Goal-directed therapy of cardiac preload in induced whole-body hyperthermia.

OBJECTIVES
To optimize volume therapy during induced whole-body hyperthermia (WBH) < or = 42.2 degrees C, pulmonary capillary wedge pressure (PCWP) and intrathoracic blood volume index (ITBVI) were compared as goal parameters.


DESIGN
Prospective clinical study.


SETTING
ICU at university hospital.


PATIENTS
Twenty-three patients with metastatic cancers.


INTERVENTIONS
Radiant WBH in combination with induced hyperglycemia, hyperoxemia, and chemotherapy was applied. Volume therapy was directed to the PCWP (group A, 8 to 12 mm Hg [20 treatments]), or to ITBVI (group B, 800 to 1,100 mL/m2 [19 treatments]) following a standardized protocol. Goals other than PCWP and ITBVI were cardiac index of > 3.5 L/min/m2 and mean arterial pressure of > 55 mm Hg.


MEASUREMENTS AND RESULTS
In addition to the primary goals PCWP and ITBVI, at defined temperatures, central venous pressure (CVP), extravascular lung water index, the number of infusions, and packed RBCs, as well as serum lactate level, norepinephrine dosage, and levels of liver enzymes, bilirubin, creatinine, and urea were measured. Patients in group A received a significantly greater mean (+/- SD) amount of crystalloids compared to those in group B (6,175 +/- 656 vs 3,947 +/- 375 mL, respectively) and required significantly lower dosages of vasoconstrictors compared with patients in group B. Except for the lower values of CVP in patients in group A during hyperthermia, all of the other hemodynamic and laboratory parameters showed no significant differences between the groups or stayed in a normal range.


CONCLUSION
PCWP and ITBVI are useful parameters to assess preload in induced WBH. Differences in crystalloids and vasopressor dosages may suggest an appropriate ITBVI of > 1,100 mL/m2 for patients with good cardiopulmonary health under such extremely hypercirculatory conditions.
Near Field Communication (NFC) Technology: A Survey

Near Field Communication, NFCis one of the latest short range wireless communication technologies. NFC provides safe communication between electronic gadgets. NFC-enabled devices can just be pointed or touched by the users of their devices to other NFC-enabled devices to communicate with them. With NFC technology, communication is established when an NFC-compatible device is brought within a few centimetres of another i.e. around 20 cm theoretically (4cm is practical). The immense benefit of the short transmission range is that it prevents eavesdropping on NFC-enabled dealings. NFC technology enables several innovative usage scenarios for mobile devices. NFC technology works on the basis of RFID technology which uses magnetic field induction to commence communication between electronic devices in close vicinity. NFC operates at 13.56MHz and has 424kbps maximum data transfer rate. NFC is complementary to Bluetooth and 802.11 with their long distance capabilities. In card emulation mode NFC devices can offer contactless/wireless smart card standard. This technology enables smart phones to replace traditional plastic cards for the purpose of ticketing, payment, etc. Sharing (share files between phones), service discovery i.e. get information by touching smart phones etc. are other possible applications of NFC using smart phones. This paper provides an overview of NFC technology in a detailed manner including working principle, transmission details, protocols and standards, application scenarios, future market, security standards and vendor’s chipsets which are available for this standard. This comprehensive survey should serve as a useful guide for students, researchers and academicians who are interested in NFC Technology and its applications [1].
Detecting Life Events in Feeds from Twitter

Short posts on micro-blogs are characterized by high ambiguity and non-standard language. We focus on detecting life events from such micro-blogs, a type of event which have not been paid much attention so far. We discuss the corpus we assembled and our experiments. Simpler models based on unigrams perform better than models that include history, number of retweets and semantic roles.
WLAN chip antenna mountable above the system ground plane of a mobile device

A novel wireless local-area network (WLAN) chip antenna suitable to be mounted above the system ground plane of a mobile device is presented. The antenna in the study is easily fabricated from folding a single metal plate onto a foam base, and mainly comprises a short-circuited radiating strip and an antenna ground. The antenna ground occupies the bottom surface and two adjacent side surfaces of the foam base. When the antenna is mounted at the corner of the system ground plane, this antenna ground structure is expected to effectively reduce the antenna's possible fringing electromagnetic fields inside the mobile device. In this case, when the associated element such as the radio-frequency shielding metal case is placed under the proposed antenna, small or negligible variations in the antenna performance are obtained. Design considerations of the proposed antenna for WLAN operation in the 2.4 GHz band are described, and results of the constructed prototypes are presented.
Strengthening and stretching for rheumatoid arthritis of the hand (SARAH): design of a randomised controlled trial of a hand and upper limb exercise intervention - ISRCTN89936343

BACKGROUND
Rheumatoid Arthritis (RA) commonly affects the hands and wrists with inflammation, deformity, pain, weakness and restricted mobility leading to reduced function. The effectiveness of exercise for RA hands is uncertain, although evidence from small scale studies is promising. The Strengthening And Stretching for Rheumatoid Arthritis of the Hand (SARAH) trial is a pragmatic, multi-centre randomised controlled trial evaluating the clinical and cost effectiveness of adding an optimised exercise programme for hands and upper limbs to best practice usual care for patients with RA.


METHODS/DESIGN
480 participants with problematic RA hands will be recruited through 17 NHS trusts. Treatments will be provided by physiotherapists and occupational therapists. Participants will be individually randomised to receive either best practice usual care (joint protection advice, general exercise advice, functional splinting and assistive devices) or best practice usual care supplemented with an individualised exercise programme of strengthening and stretching exercises. The study assessors will be blinded to treatment allocation and will follow participants up at four and 12 months. The primary outcome measure is the Hand function subscale of the Michigan Hand Outcome Questionnaire, and secondary outcomes include hand and wrist impairment measures, quality of life, and resource use. Economic and qualitative studies will also be carried out in parallel.


DISCUSSION
This paper describes the design and development of a trial protocol of a complex intervention study based in therapy out-patient departments. The findings will provide evidence to support or refute the use of an optimised exercise programme for RA of the hand in addition to best practice usual care.
Silica gel functionalized with resacetophenone: synthesis of a new chelating matrix and its application as metal ion collector for their flame atomic absorption spectrometric determination as metal ion collector for their flame atomic absorption spectrometric determination

Silica gel modified with 3-aminopropyltriethoxysilane was anchored with resacetophenone to prepare a new chelating surface (or matrix). It was characterized with cross polarization magic angle spinning C NMR spectroscopy and diffuse reflectance infrared Fourier transform (DRIFT) spectroscopy and used for the separation and preconcentration of Cu(II), Pb(II), Ni(II), Fe(III), Cd(II), Zn(II) and Co(II) prior to their determination by flame atomic absorption spectrometry (FAAS). The optimum pH ranges for quantitative sorption are 6.0-7.5, 5.5-7.5, 5.0-7.0, 6.5-7.5, 6.0-7.5, 6.0-7.0 and 6.0-7.5 for Cu, Pb, Fe, Zn, Co, Ni and Cd, respectively. All the metals can be desorbed with 3 mol dm" HCl or HNO3. The sorption capacity for these metal ions is in range of 57.8-365.0 (xmolg^ of chelating matrix. Tolerance limits for electrolytes NaNO3, NaCl, NaBr, Na2SO4 and Na3PO4 and cations Ca(II) and Mg(II) in the sorption of these metal ions are reported. Preconcentration factors of 200, 300, 150, 250, 250, 200 and 200 for Cd, Co, Zn, Cu, Pb, Fe and Ni, respectively, are obtained and t1/2 values are < 1 min except for Cd. 95% extraction by a batch method takes <25 min. The simultaneous enrichment and determination of all the metals are possible if the total load of the metal ions is less than the sorption capacity. In river water samples all these metal ions were enriched with the present matrix and determined with a flame atomic absorption spectrometer (R.S.D. < 7.7%). Copper contents of pharmaceutical samples (vitamin capsule) were preconcentrated with the present chelating matrix and estimated with flame AAS, with R.S.D. ~ 2.2%. The results are in the good agreement with the certified value, 0.4 mg/g of capsule.
Macrostructural abnormalities in Korsakoff syndrome compared with uncomplicated alcoholism.

OBJECTIVE
To distinguish, in patients with Korsakoff syndrome (KS), the structural brain abnormalities shared with alcoholic patients without KS (AL), from those specific to KS.


METHODS
MRI data were collected in 11 alcoholic patients with KS, 34 alcoholic patients without KS, and 25 healthy control subjects (CS). Gray and white matter volumes were compared in the 3 groups using a voxel-based approach.


RESULTS
A conjunction analysis indicated a large pattern of shared gray and white matter volume deficits in AL and KS. There were graded effects of volume deficits (KS < AL < CS) in the medial portion of the thalami, hypothalamus (mammillary bodies), left insula, and genu of the corpus callosum. Abnormalities in the left thalamic radiation were observed only in KS.


CONCLUSIONS
Our results indicate considerable similarities in the pattern of gray and white matter damage in AL and KS. This finding confirms the widespread neurotoxic effect of chronic alcohol consumption. Only a few cerebral regions, including the medial thalami, mammillary bodies, and corpus callosum, were more severely damaged in KS than in AL. The continuum of macrostructural damage from AL to KS is therefore restricted to key brain structures. Longitudinal investigations are required to determine whether alcoholic patients with medial thalamic volumes that are comparable to those of patients with KS are at increased risk of developing KS.