LLukas22/scidocs huggingface dataset:
Relationships between media and audiences : prospects for audience reception studies

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Effect of Rain Attenuation for a 10-Gb/s 120-GHz-Band Millimeter-Wave Wireless Link

We measured the effects of rain attenuation on 120-GHz band wireless link during the heavy rainy period (from July to September, 2008) and annual period (from March to December, 2008). The heavy rainy period data are used as a basis for the wireless link design, and the annual data are used to calculate the reliability of the wireless link. The 120-GHz band wireless link with V polarization was operated on a 400-m-long path from March to December 2008 in Atsugi, Japan. The rain rate distribution for Atsugi is in good agreement with the conditional M distributions. As for rain attenuation, the annual data coincide with the ITU and Laws and Parsons models. Cumulative distributions of attenuation and bit-error-rate deterioration due to rain were obtained.
[Patient Questionnaire for Assessment of Rehabilitation Motivation (PAREMO-20) - psychometric evaluation and validation in a sample of cancer patients with different tumour sites].

OBJECTIVES
A significant body of research suggests that patient motivation is related to better rehabilitation outcome with regard to psychosocial and physical well-being. Thus, patient motivation gains increasing attention with regard to the course of treatment and individual treatment planning in the practice and research in medical rehabilitation. This study aims to validate the PAREMO-20, a measure of rehabilitation motivation in a sample of cancer patients with different tumour sites.


METHODS
1193 cancer patients participated in a prospective study evaluating the medical and psychosocial effects of inpatient cancer rehabilitation. A set of various questionnaires was completed at the beginning and at the end of the rehabilitation measure as well as at one year follow-up (participation rate at follow-up: 78%). The PAREMO-20 was psychometrically examined on this sample. Validity was examined using a cancer-specific questionnaire for individual therapy goals, as well as the HADS-D and the SF-8.


RESULTS
The original six factors were replicated. The factor solution emerging through PCA was tested with a confirmatory factor analysis. Maximum likelihood estimation of this model produced good fit statistics. Internal consistencies were high to satisfactory with Cronbach's Alpha=0.88 to Alpha=0.59. Psychological distress and physical impairments were positively associated with anxiety and depression, as well as with therapy goal dimensions. Moderate to high (negative) correlations were observed with health related quality of life, in particular with the mental-health dimension (r=-0.74, p=0.01).


DISCUSSION
The PAREMO-20 is a reliable, valid and economic instrument, which can be recommended for use in clinical care.
Transport Infrastructure and Firm Location Choice in Equilibrium : Evidence from Indonesia ’ s Highways

Transport improvements make it easier for firms to reach customers from a given site, encouraging them to agglomerate. On the other hand, by expanding access to cheaper labor and land, lower transport costs make producing in more sites feasible, promoting dispersion. To better understand how transport improvements affect the spatial distribution of economic activity, I study how the location choices of new manufacturers responded to changes in road quality in Indonesia. Using new data, I document massive upgrades to Indonesia’s highway networks during the 1990s, a period in which national transportation funding increased by 83 percent. I first show that these road improvements were accompanied by a significant dispersion of manufacturing activity, and that different industries responded in ways predicted by theory. To make better counterfactual predictions, I develop a structural model of location choice in which firms face a trade off: locating closer to demand sources requires firms to pay higher factor prices. The model predicts that some location characteristics relevant to firms are determined in equilibrium, necessitating the use of instrumental variables. I estimate a random coefficients logit model with endogenous choice characteristics and find significant differences in firms’ willingness to pay for greater market access across different industrial sectors. Counterfactual policy simulations suggest that new toll roads connecting urban areas would cause a modest amount of industrial suburbanization. In contrast, upgrading rural roads would have little or no effect on equilibrium firm locations. ∗Department of Economics, University of California, Berkeley. I thank Frederico Finan, Paul Gertler, Bryan Graham, Robert Helsley, Maximilian Kasy, Patrick Kline, Edward Miguel, and Sarath Sanga for helpful comments and suggestions. I also thank Glen Stringer for several invaluable detailed discussions about the IRMS dataset, as well as Ir. Taufik Widjoyono, Ir. Julius J. Sohilait, and Yohanes Richwanto at Departmen Pekerjaan Umum for generously granting me access to their data and answering my many questions about it. This work was supported, in part, by fellowships and grants from several centers at U.C. Berkeley, including the Fischer Center for Real Estate and Urban Economics, the Center for Equitable Growth, the Institute of Business and Economic Research, and the Center of Evaluation for Global Action.
Validation of an Informant-Reported Web-Based Data Collection to Assess Dementia Symptoms

BACKGROUND
The Web offers unprecedented access to the experience of people with dementia and their care partners, but data gathered online need to be validated to be useful.


OBJECTIVE
To test the construct validity of an informant Web-based data collection to assess dementia symptoms in relation to the 15-point Dependence Scale (DS).


METHODS
In an online survey posted on the DementiaGuide website, care partners of people with dementia built individualized profiles from the 60-item SymptomGuide and completed a questionnaire, which included the DS and a staging tool.


RESULTS
In the 250 profilees (155, 62% women, mean age 77 years), increasing dependence was associated with a greater chance of institutionalization. For example, no one at the lowest levels of dependence (DS score < 5, n = 33) was in long-term care, compared with half (13/25) of the profilees at the highest levels of dependence (DS score > 12) being in institutions (χ(2)(4) = 27.9, P < .001). The Web-based DS was correlated with the number of symptoms: higher DS scores were associated with a higher stage of dementia (F > 50, P < .001).


CONCLUSION
In an online survey, the Web-based DS showed good construct validity, potentially demonstrating how the Web can be used to learn more about dementia progression and how it relates to symptoms experienced by patients across the course of dementing illnesses. Even so, caution is needed to assure the validity of data collected online.
In vivo detection of postictal perturbations of cerebral metabolism by use of proton MR spectroscopy: preliminary results in a canine model of prolonged generalized seizures.

BACKGROUND AND PURPOSE
Biochemical studies of seizures in patients and laboratory animals have monitored postictal perturbations in cerebral metabolism with either invasive techniques or with such noninvasive techniques as nuclear medicine, MR imaging, in vivo phosphorus MR spectroscopy (MRS), and in vivo proton MRS at field strengths of 1.5 T or above. We investigated postictal metabolic changes in a generalized seizure model with in vivo proton MRS at 0.5 T, in which the combination of glutamate and glutamine resonances (denoted glx) can be modeled as a singlet.


METHODS
Five adult mongrel dogs underwent control and postictal experiments in which single-voxel proton MR spectra were obtained from the right frontal lobe cortex with a point-resolved spectroscopy technique approximately every 20 minutes for 3 hours. N-acetylaspartate (NAA), glx, and creatine (Cr) were quantified in absolute millimolar units with a cerebral water-referenced algorithm. Inter- and intrasubject differences in mean metabolite concentrations collected throughout the 3-hour period were compared using an unpaired, two-tailed Student's t test at a.05 level of significance.


RESULTS
We found a significant increase (15.4%) in the postictal intersubject mean glx concentration, as well as a 23.7% postictal decrease in the intersubject mean Cr concentration. A trend toward a subtle decrease in postictal intersubject mean NAA concentration was not statistically significant. We also observed a substantial qualitative increase in the combination of postictal lactate and free fatty acid peaks.


CONCLUSIONS
The glx, NAA, lactate, and free fatty acid results are in general agreement with previous studies of postictal perturbations in cerebral metabolism measured with invasive biochemical or noninvasive high-field-strength in vivo MRS detection assays. Given a high sensitivity for glx at 0.5 T relative to 1.5 T, further studies of postictal mesial temporal lobe structures are warranted in chronic animal preparations that model temporal lobe epilepsy.
Polymorphism of the DQA1 promoter region (QAP) and DRB1, QAP, DQA1, DQB1 haplotypes in systemic lupus erythematosus

We have investigated the DNA polymorphism for the DQA1 promoter region (QAP) and HLA-class II DRB1, DQA1, and DQB1 genes in 178 central European patients with Systemic lupus erythematosus (SLE) using polymerase chain reaction and Dig-ddUTP labeled oligonucleotides. Increased frequencies of DRB1*02 and *03 are confirmed by DNA typing. In addition, the frequencies of DQA1*0501, *0102 and DQB1*0201, *0602 alleles are increased in the patients as compared to controls. The strongest association to SLE is found with DRB1*03 and DQB1*0201 alleles (p<10−7, p corr. <10−5 and p<10−6, p corr. <10−4, respectively). By investigating the DQA1 promoter region in the SLE patients we have detected nine different QAP variants. Increased frequencies of QAP1.2 and QAP4.1 are observed in patients as compared to controls (p <0.05, p corr. = n. s.). Analysis of linkage disquilibria demonstrates a very strong association between QAP variants and DQA1, DRB1 alleles. Certain QAP variants are completely associated with DQA1 and DRB1 alleles, whereas others can combine with different DQA1 and DRB1 alleles. All DRB1*02-positive patients and controls carry QAP1.2, and all DRB1*03-positive patients and controls carry QAP4.1. Conversely, the QAP1.2 variant appears only in DRB1*02 haplotypes, while the QAP4.1 variant can be observed in DRB1*03, *11, and *1303 haplotypes. Based on the strong linkage disequilibria between DRB1-DQA1-DQB1 genes and between DRB1-QAP-DQA1, we have deduced the four-point haplotypes for DRB1-QAP-DQA1-DQB1 in patients and controls. Two haplotypes DRB1*02-QAP1.2-DQA1*0102-DQB1*0602-and DRB1*03-QAP4.1-DQA1*0501-DQB1*0201 are significantly increased in patient as compared to controls (p<0.01, p corr. = n.s., RR = 1.8 and p <10−7, p corr. <10−5, RR = 3.1, respectively). The analysis of relative risks attributed to the various alleles of QAP, DQA1, and DQB1 as well as the investigation of the deduced DRB1-QAP-DQA1-DQB1 haplotypes leads to the conclusion that QAP4.1 and DQA1*0501 on the DR3 haplotypes are probably not involved in SLE susceptibility. There is no evidence for the involvement of DQ2 α/β dimers coded in transposition. Thus, susceptibility to SLE is on the DR3 haplotype most probably localized at DRB1 or telomeric of DRB1, while for the DR2 haplotype such orientation cannot be given.
Predicting Potential Speedup of Serial Code via Lightweight Profiling and Emulations with Memory Performance Model

We achieve very small runtime overhead: approximately a 1.2-10 times slowdown and moderate memory consumption. We demonstrate the effectiveness of Parallel Prophet in eight benchmarks in the Omp SCR and NAS Parallel benchmarks by comparing our predictions with actual parallelized code. Our simple memory model also identifies performance limitations resulting from the memory system contention. We present Parallel Prophet, which projects potential parallel speedup from an annotated serial program before actual parallelization. Programmers want to see how much speedup could be obtained prior to investing time and effort to write parallel code. With Parallel Prophet, programmers simply insert annotations that describe the parallel behavior of the serial program. Parallel Prophet then uses lightweight interval profiling and dynamic emulations to predict potential performance benefit. Parallel Prophet models many realistic features of parallel programs: unbalanced workload, multiple critical sections, nested and recursive parallelism, and specific thread schedulings and paradigms, which are hard to model in previous approaches. Furthermore, Parallel Prophet predicts speedup saturation resulting from memory and caches by onitoring cache hit ratio and bandwidth consumption in a serial program. We achieve very small runtime overhead: approximately a 1.2-10 times slowdown and moderate memory consumption. We demonstrate the effectiveness of Parallel Prophet in eight benchmarks in the OmpSCR and NAS Parallel benchmarks by comparing our predictions with actual parallelized code. Our simple memory model also identifies performance limitations resulting from memory system contention.
ESD protection design for CMOS RF integrated circuits

ESD protection design for CMOS RF integrated circuits is proposed in this paper by using the stacked polysilicon diodes as the input ESD protection devices to reduce the total input capacitance and to avoid the noise coupling from the common substrate. The ESD level of the stacked polysilicon diodes on the I/O pad is restored by using the turn-on efficient power-rail ESD clamp circuit, which is constructed by substrate-triggered technique. This polysilicon diode is fully process-compatible to general sub-quarter-micron CMOS processes.
Supplier Selection Criteria and Methods in Supply Chains : A Review

An effective supplier selection process is very important to the success of any manufacturing organization. The main objective of supplier selection process is to reduce purchase risk, maximize overall value to the purchaser, and develop closeness and long-term relationships between buyers and suppliers in today’s competitive industrial scenario. The literature on supplier selection criteria and methods is full of various analytical and heuristic approaches. Some researchers have developed hybrid models by combining more than one type of selection methods. It is felt that supplier selection criteria and method is still a critical issue for the manufacturing industries therefore in the present paper the literature has been thoroughly reviewed and critically analyzed to address the issue. Keywords—Supplier selection, AHP, ANP, TOPSIS, Mathematical Programming.
The Ontology of Biological and Clinical Statistics (OBCS) for standardized and reproducible statistical analysis

BACKGROUND
Statistics play a critical role in biological and clinical research. However, most reports of scientific results in the published literature make it difficult for the reader to reproduce the statistical analyses performed in achieving those results because they provide inadequate documentation of the statistical tests and algorithms applied. The Ontology of Biological and Clinical Statistics (OBCS) is put forward here as a step towards solving this problem.


RESULTS
The terms in OBCS including 'data collection', 'data transformation in statistics', 'data visualization', 'statistical data analysis', and 'drawing a conclusion based on data', cover the major types of statistical processes used in basic biological research and clinical outcome studies. OBCS is aligned with the Basic Formal Ontology (BFO) and extends the Ontology of Biomedical Investigations (OBI), an OBO (Open Biological and Biomedical Ontologies) Foundry ontology supported by over 20 research communities. Currently, OBCS comprehends 878 terms, representing 20 BFO classes, 403 OBI classes, 229 OBCS specific classes, and 122 classes imported from ten other OBO ontologies. We discuss two examples illustrating how the ontology is being applied. In the first (biological) use case, we describe how OBCS was applied to represent the high throughput microarray data analysis of immunological transcriptional profiles in human subjects vaccinated with an influenza vaccine. In the second (clinical outcomes) use case, we applied OBCS to represent the processing of electronic health care data to determine the associations between hospital staffing levels and patient mortality. Our case studies were designed to show how OBCS can be used for the consistent representation of statistical analysis pipelines under two different research paradigms. Other ongoing projects using OBCS for statistical data processing are also discussed. The OBCS source code and documentation are available at: https://github.com/obcs/obcs .


CONCLUSIONS
The Ontology of Biological and Clinical Statistics (OBCS) is a community-based open source ontology in the domain of biological and clinical statistics. OBCS is a timely ontology that represents statistics-related terms and their relations in a rigorous fashion, facilitates standard data analysis and integration, and supports reproducible biological and clinical research.
Efficient randomized algorithms for robust estimation of circular arcs and aligned ellipses

Fitting two-dimensional conic sections (e.g., circular and elliptical arcs) to a finite collection of points in the plane is an important problem in statistical estimation and has significant industrial applications. Recently there has been a great deal of interest in robust estimators, because of their lack of sensitivity to outlying data points. The basic measure of the robustness of an estimator is its breakdown point, that is, the fraction (up to 50%) of outlying data points that can corrupt the estimator. In this paper we introduce nonlinear Theil-Sen and repeated median (RM) variants for estimating the center and radius of a circular arc, and for estimating the center and horizontal and vertical radii of an axis-aligned ellipse. The circular arc estimators have breakdown points of ≈ 21% and 50%, respectively, and the ellipse estimators have breakdown points of ≈ 16% and 50%, respectively. We present randomized algorithms for these estimators, whose expected running times are O(n2 log n) for the circular case and O(n3 log n) for the elliptical case. All algorithms use O(n) space in the worst case.
The cancer stem cell: premises, promises and challenges

Over the last decade, the notion that tumors are maintained by their own stem cells, the so-called cancer stem cells, has created great excitement in the research community. This review attempts to summarize the underlying concepts of this notion, to distinguish hard facts from beliefs and to define the future challenges of the field.
Feeding elicitors and precursors enhance colchicine accumulation in morphogenic cultures of Gloriosa superba L.

Morphogenic cultures of Gloriosa superba were initiated on Murashige and Skoog’s medium fortified with 2 mg L−1 2,4-dichlorophenoxyacetic acid (2,4-D), 0.5 mg L−1 naphthaleneacetic acid (NAA), 4% sucrose and 0.1% activated charcoal. To enhance the content of the alkaloid colchicine, morphogenic cultures were treated with different concentrations of abiotic elicitors like signalling compounds, metals, biotic elicitors, precursors and a combination of elicitors. Signalling molecules like acetyl salicylic acid (ASA) and sodium nitroprusside improved the production of colchicine. Abiotic elicitors have markedly (p ≤ 0.05 or ≤ 0.01) enhanced the colchicine content either at lower or higher concentrations. Among the metals, the highest amount of 11.67 mg of colchicine g−1 dry wt was noticed at 60 mM rubidium chloride, followed by 60 mM NaCl (11.18 mg g−1). Contrarily, in the presence of biotic elicitors such as Fusarium oxysporum, Alternaria solani, and Saccharomyces cerevisiae, colchicine content ranged only between 2 and 5.32 mg g−1, but Bacillus subtilis repressed it. Among the aromatic amino acids, phenylalanine at 500 mg L−1 influenced the highest accumulation of 19.48 mg g−1 dry tissue, followed by tryptophan (12.47 mg g−1), and tyrosine (9.87 mg g−1), a direct precursor of colchicine biosynthesis, while intact tubers and leaves contained 4.65 and 4.16 mg of colchicine g−1 dry tissue respectively. A combination of 10 µM AlCl3 and 50 µM salicylic acid (SA) registered 17.34 mg g−1 followed by 16.24 mg g−1 tissue in presence of 1 µM HgCl2 and 50 µM SA. The results suggest that the elicitor-stimulated colchicine accumulation was a stress response and can be exploited further for commercial production.
Distributed Supervisory Predictive Control of Distributed Wind and Solar Energy Systems

In this work, we design a distributed supervisory model predictive control (MPC) system for optimal management and operation of distributed wind and solar energy generation systems integrated into the electrical grid to facilitate the development of the so-called “smart electrical grid”. We consider a topology in which two spatially distributed energy generation systems, a wind subsystem and a solar subsystem, are integrated in a DC power grid, providing electrical power to a local area, and each subsystem is coupled with an energy storage device. A supervisory MPC optimization problem is first formulated to take into account optimality considerations on system operation and battery maintenance; then a sequential and an iterative distributed supervisory MPC architectures are developed to coordinate the actions of the subsystems accordingly. Simulations of 24-hour system operation are carried out under the different control architectures to demonstrate the applicability and effectiveness of the distributed supervisory predictive control design.
Oxytocin in Pregnancy and the Postpartum: Relations to Labor and Its Management

The purpose of this study was to examine variations in endogenous oxytocin levels in pregnancy and postpartum state. We also explored the associations between delivery variables and oxytocin levels. A final sample of 272 mothers in their first trimester of pregnancy was included for the study. Blood samples were drawn during the first trimester and third trimester of pregnancy and at 8 weeks postpartum. Socio-demographic data were collected at each time point and medical files were consulted for delivery details. In most women, levels of circulating oxytocin increased from the first to third trimester of pregnancy followed by a decrease in the postpartum period. Oxytocin levels varied considerably between individuals, ranging from 50 pg/mL to over 2000 pg/mL. Parity was the main predictor of oxytocin levels in the third trimester of pregnancy and of oxytocin level changes from the first to the third trimester of pregnancy. Oxytocin levels in the third trimester of pregnancy predicted a self-reported negative labor experience and increased the chances of having an epidural. Intrapartum exogenous oxytocin was positively associated with levels of oxytocin during the postpartum period. Our exploratory results suggest that circulating oxytocin levels during the third trimester of pregnancy may predict the type of labor a woman will experience. More importantly, the quantity of intrapartum exogenous oxytocin administered during labor predicted plasma oxytocin levels 2 months postpartum, suggesting a possible long-term effect of this routine intervention, the consequences of which are largely unknown.