LLukas22/scidocs huggingface dataset:
Internal Dynamic Partial Reconfiguration for Real Time Signal Processing on FPGA

Few FPGAs support creation of partially reconfigurable systems when compared to traditional systems based on total reconfiguration. This allows dynamic change of the functionalities hosted on the device when needed and while the rest of the system continues its working. Runtime partial reconfiguration of FPGA is an attractive feature which offers countless benefits across multiple industries. Xilinx has supported partial reconfiguration for many generations of devices. This can be taken advantage of substituting inactive parts of hardware systems and to adapt the complete chip a different requirement of an application. This paper describes an innovative implementation for real time audio and video processing using run time internal partial reconfiguration. System is implemented on Virtex-4 FPGA. Internal reconfiguration is handled using internal configuration access port (ICAP) driven by soft processor core. The considerable savings in device resources, bit stream size and configuration time is observed and tabulated in this paper.
A randomized phase II study of pazopanib in hormone sensitive prostate cancer: a University of Chicago Phase II Consortium/ Department of Defense Prostate Cancer Clinical Trials Consortium study

Background:Intermittent androgen suppression (IAS) is an increasingly popular treatment option for castrate-sensitive prostate cancer. On the basis of previous data with anti-angiogenic strategies, we hypothesized that pan-inhibition of the vascular endothelial growth factor receptor using pazopanib during the IAS off period would result in prolonged time to PSA failure.Methods:Men with biochemically recurrent prostate cancer, whose PSA was <0.5 ng ml−1 after 6 months of androgen deprivation therapy were randomized to pazopanib 800 mg daily or observation. The planned primary outcome was time to PSA progression >4.0 ng ml−1.Results:Thirty-seven patients were randomized. Of 18 patients randomized to pazopanib, at the time of study closure, 4 had progressive disease, 1 remained on treatment and 13 (72%) electively disenrolled, the most common reason being patient request due to grade 1/2 toxicity (8 patients). Two additional patients were removed from treatment due to adverse events. Of 19 patients randomized to observation, at the time of study closure, 4 had progressive disease, 7 remained under protocol-defined observation and 8 (42%) had disenrolled, most commonly due to non-compliance with protocol visits (3 patients). Because of high dropout rates in both arms, the study was halted.Conclusions:IAS is a treatment approach that may facilitate investigation of novel agents in the hormone-sensitive state. This trial attempted to investigate the role of antiangiogenic therapy in this setting, but encountered several barriers, including toxicities and patient non-compliance, which can make implementation of such a study difficult. Future investigative efforts in this arena should carefully consider drug toxicity and employ a design that maximizes patient convenience to reduce the dropout rate.
Bijective proofs of Gould's and Rothe's identities

We first give a bijective proof of Gould's identity in the model of binary words. Then we deduce Rothe's identity from Gould's identity again by a bijection, which also leads to a double-sum extension of the q-Chu-Vandermonde formula.
Paralleling Of Power MOSFETs For Higher Power Output

For worst case parameter mismatch, modest levels of unbalance are predicted through the use of minimum gate decoupling, dynamic load lines with high Q values, common source inductance or high yield screening. Each technique is evaluated in terms of current unbalance, transition energy, peak turn-off voltage and parasitic oscillations, as appropriate, for various pulse duty cycles and frequency ranges.
Repetitive transcranial magnetic stimulation to SMA worsens complex movements in Parkinson ' s disease

Objectives: To evaluate the therapeutic potential of repetitive transcranial magnetic stimulation (rTMS) for Parkinson's disease (PD) by delivering stimulation at higher intensity and frequency over longer time than in previous research. Promising bene®cial effects on movement during or after rTMS have been reported. Methods: Ten patients with idiopathic PD were enrolled in a randomized crossover study comparing active versus sham rTMS to the supplementary motor area (SMA). Assessments included reaction and movement times (RT/MT), quantitative spiral analysis, timed motor performance tests, United Parkinson's Disease Rating Scale (UPDRS), patient self-report and guess as to stimulation condition. Results: Two of 10 patients could not tolerate the protocol. Thirty to 45 min following stimulation, active rTMS as compared with sham stimulation worsened spiral drawing (P  0:001) and prolonged RT in the most affected limb (P  0:030). No other signi®cant differences were detected. Conclusions: We sought clinically promising improvement in PD but found subclinical worsening of complex and preparatory movement following rTMS to SMA. These results raise safety concerns regarding the persistence of dysfunction induced by rTMS while supporting the value of rTMS as a research tool. Studies aimed at understanding basic mechanisms and timing of rTMS effects are needed. q 2001 Elsevier Science Ireland Ltd. All rights reserved.
Metabolic Signatures of Cultured Human Adipocytes from Metabolically Healthy versus Unhealthy Obese Individuals

BACKGROUND AND AIMS
Among obese subjects, metabolically healthy and unhealthy obesity (MHO/MUHO) can be differentiated: the latter is characterized by whole-body insulin resistance, hepatic steatosis, and subclinical inflammation. Aim of this study was, to identify adipocyte-specific metabolic signatures and functional biomarkers for MHO versus MUHO.


METHODS
10 insulin-resistant (IR) vs. 10 insulin-sensitive (IS) non-diabetic morbidly obese (BMI >40 kg/m2) Caucasians were matched for gender, age, BMI, and percentage of body fat. From subcutaneous fat biopsies, primary preadipocytes were isolated and differentiated to adipocytes in vitro. About 280 metabolites were investigated by a targeted metabolomic approach intracellularly, extracellularly, and in plasma.


RESULTS/INTERPRETATION
Among others, aspartate was reduced intracellularly to one third (p = 0.0039) in IR adipocytes, pointing to a relative depletion of citric acid cycle metabolites or reduced aspartate uptake in MUHO. Other amino acids, already known to correlate with diabetes and/or obesity, were identified to differ between MUHO's and MHO's adipocytes, namely glutamine, histidine, and spermidine. Most species of phosphatidylcholines (PCs) were lower in MUHO's extracellular milieu, though simultaneously elevated intracellularly, e.g., PC aa C32∶3, pointing to increased PC synthesis and/or reduced PC release. Furthermore, altered arachidonic acid (AA) metabolism was found: 15(S)-HETE (15-hydroxy-eicosatetraenoic acid; 0 vs. 120pM; p = 0.0014), AA (1.5-fold; p = 0.0055) and docosahexaenoic acid (DHA, C22∶6; 2-fold; p = 0.0033) were higher in MUHO. This emphasizes a direct contribution of adipocytes to local adipose tissue inflammation. Elevated DHA, as an inhibitor of prostaglandin synthesis, might be a hint for counter-regulatory mechanisms in MUHO.


CONCLUSION/INTERPRETATION
We identified adipocyte-inherent metabolic alterations discriminating between MHO and MUHO.
Does acute passive stretching increase muscle length in children with cerebral palsy?

BACKGROUND
Children with spastic cerebral palsy experience increased muscle stiffness and reduced muscle length, which may prevent elongation of the muscle during stretch. Stretching performed either by the clinician, or children themselves is used as a treatment modality to increase/maintain joint range of motion. It is not clear whether the associated increases in muscle-tendon unit length are due to increases in muscle or tendon length. The purpose was to determine whether alterations in ankle range of motion in response to acute stretching were accompanied by increases in muscle length, and whether any effects would be dependent upon stretch technique.


METHODS
Eight children (6-14 y) with cerebral palsy received a passive dorsiflexion stretch for 5 × 20 s to each leg, which was applied by a physiotherapist or the children themselves. Maximum dorsiflexion angle, medial gastrocnemius muscle and fascicle lengths, and Achilles tendon length were calculated at a reference angle of 10 ° plantarflexion, and at maximum dorsiflexion in the pre- and post-stretch trials.


FINDINGS
All variables were significantly greater during pre- and post-stretch trials compared to the resting angle, and were independent of stretch technique. There was an approximate 10 ° increase in maximum dorsiflexion post-stretch, and this was accounted for by elongation of both muscle (0.8 cm) and tendon (1.0 cm). Muscle fascicle length increased significantly (0.6 cm) from pre- to post-stretch.


INTERPRETATION
The results provide evidence that commonly used stretching techniques can increase overall muscle, and fascicle lengths immediately post-stretch in children with cerebral palsy.
Risk communication and informed consent in the medical tourism industry: A thematic content analysis of canadian broker websites

BACKGROUND
Medical tourism, thought of as patients seeking non-emergency medical care outside of their home countries, is a growing industry worldwide. Canadians are amongst those engaging in medical tourism, and many are helped in the process of accessing care abroad by medical tourism brokers - agents who specialize in making international medical care arrangements for patients. As a key source of information for these patients, brokers are likely to play an important role in communicating the risks and benefits of undergoing surgery or other procedures abroad to their clientele. This raises important ethical concerns regarding processes such as informed consent and the liability of brokers in the event that complications arise from procedures. The purpose of this article is to examine the language, information, and online marketing of Canadian medical tourism brokers' websites in light of such ethical concerns.


METHODS
An exhaustive online search using multiple search engines and keywords was performed to compile a comprehensive directory of English-language Canadian medical tourism brokerage websites. These websites were examined using thematic content analysis, which included identifying informational themes, generating frequency counts of these themes, and comparing trends in these counts to the established literature.


RESULTS
Seventeen websites were identified for inclusion in this study. It was found that Canadian medical tourism broker websites varied widely in scope, content, professionalism and depth of information. Three themes emerged from the thematic content analysis: training and accreditation, risk communication, and business dimensions. Third party accreditation bodies of debatable regulatory value were regularly mentioned on the reviewed websites, and discussion of surgical risk was absent on 47% of the websites reviewed, with limited discussion of risk on the remaining ones. Terminology describing brokers' roles was somewhat inconsistent across the websites. Finally, brokers' roles in follow up care, their prices, and the speed of surgery were the most commonly included business dimensions on the reviewed websites.


CONCLUSION
Canadian medical tourism brokers currently lack a common standard of care and accreditation, and are widely lacking in providing adequate risk communication for potential medical tourists. This has implications for the informed consent and consequent safety of Canadian medical tourists.
Radon concentrations in hot spring waters in northern Venezuela.

Concentrations of 222Rn were determined in selected thermal water samples of the northern region of Venezuela. Concentrations in the range of 1}560 Bq/l were found. Soil radon concentrations and air radon concentrations related to the high values of radon concentration in water were investigated in El Castan8 o and at a spa in Las Trincheras. An outstandingly high radon e%ux was found in Las Trincheras with an average soil radon concentration of 122 kBq/m3, and an air radon concentration of 54 kBq/m3 in inhalation treatment pipes. Dose calculations revealed that regular consumption of the measured water samples presents an extra dose of radiation that may range up to 4 mSv/y. ( 1999 Elsevier Science Ltd. All rights reserved.
Direct Marketing, Indirect Profits: A Strategic Analysis of Dual - Channel Supply - Chain Design

Wei-yu Kevin Chiang • Dilip Chhajed • James D. Hess Department of Information Systems, University of Maryland at Baltimore County, Baltimore, Maryland 21250 Department of Business Administration, University of Illinois at Urbana–Champaign, Champaign, Illinois 61820 Department of Business Administration, University of Illinois at Urbana–Champaign, Champaign, Illinois 61820 kevin@wchiang.net • chhajed@uiuc.edu • jhess@uiuc.edu
Emergency Department Divert Avoidance Using Petri Nets

Emergency department overcrowding has become a major issue over the past decade. This research investigates emergency department overcrowding resulting ambulance divert. Patient flow models of the emergency department were developed using Petri Nets. The objective of these models is two-fold, to analyze patient flow in the emergency department and to assist in determining the minimum sequence of events leading a hospital from desirable operating state to divert states. A two-phase mixed-integer programming formulation was used to generate the set of minimum sequence of events. This is an on-going research, and the results of this paper shall be used to develop control policies for hospital divert avoidance.
The controlled single particle: A new concept in odd-mass nuclei

Abstract In this paper, we discuss a new concept in studying odd-mass nuclei called “the controlled single particle”. After introducing this new concept, we will use it in reproducing some experimental data of 155 Tb and compare the results. We show that using this concept, we can express some different excited bands, in addition, the ground band in odd-mas nuclei whether the party is changed or not.
Hip abductor control in walking following stroke -- the immediate effect of canes, taping and TheraTogs on gait.

OBJECTIVE
To confirm previous findings that hip abductor activity measured by electromyography (EMG) on the side contralateral to cane use is reduced during walking in stroke patients. To assess whether an orthosis (TheraTogs) or hip abductor taping increase hemiplegic hip abductor activity compared with activity during cane walking or while walking without aids. To investigate the effect of each condition on temporo-spatial gait parameters.


DESIGN
Randomized, within-participant experimental study.


SETTING
Gait laboratory.


SUBJECTS
Thirteen patients following first unilateral stroke.


INTERVENTION
Data collection over six gait cycles as subjects walked at self-selected speed during: baseline (without aids) and in randomized order with (1) hip abductor taping, (2) TheraTogs, (3) cane in non-hemiplegic hand.


MAIN MEASURES
Peak EMG of gluteus medius and tensor fascia lata and temporo-spatial gait parameters.


RESULTS
Cane use reduced EMG activity in gluteus medius from baseline by 21.86%. TheraTogs increased it by 16.47% (change cane use-TheraTogs P = 0.001, effect size = -0.5) and tape by 5.8% (change cane use-tape P = 0.001, effect size = -0.46). In tensor fascia lata cane use reduced EMG activity from baseline by 19.14%. TheraTogs also reduced EMG activity from baseline by 1.10% (change cane use-TheraTogs P = 0.009, effect size -0.37) and tape by 3% (not significant). Gait speed (m/s) at: baseline 0.44, cane use 0.45, tape 0.48, TheraTogs 0.49.


CONCLUSION
Hip abductor taping and TheraTogs increase hemiplegic hip abductor activity and gait speed during walking compared with baseline and cane use.
An Areal Rainfall Estimator Using Differential Propagation Phase: Evaluation Using a C-Band Radar and a Dense Gauge Network in the Tropics

An areal rainfall estimator based on differential propagation phase is proposed and evaluated using the Bureau of Meteorology Research Centre (BMRC) C-POL radar and a dense gauge network located near Darwin, Northern Territory, Australia. Twelve storm events during the summer rainy season (December 1998–March 1999) are analyzed and radar–gauge comparisons are evaluated in terms of normalized error and normalized bias. The areal rainfall algorithm proposed herein results in normalized error of 14% and normalized bias of 5.6% for storm total accumulation over an area of around 100 km2. Both radar measurement error and gauge sampling error are minimized substantially in the areal accumulation comparisons. The high accuracy of the radar-based method appears to validate the physical assumptions about the rain model used in the algorithm, primarily a gamma form of the drop size distribution model, an axis ratio model that accounts for transverse oscillations for D # 4 mm and equilibrium shapes for D . 4 mm, and a Gaussian canting angle distribution model with zero mean and standard deviation 108. These assumptions appear to be valid for tropical rainfall.
Calculation of transient puffer pressure rise takes mechanical compression, nozzle ablation, and arc energy into consideration

Thermal puffer-type gas circuit breaker (GCB) has a high dielectric and current interruption capability. In order to design a good thermal puffer GCB, it is important to know the blast pressure for arc cooling. Although pressure calculation programs have been developed and used for design work, the basic characteristics, such as contribution of nozzle ablation gas to puffer pressure rise, amount of back flow gas to puffer chamber, and pressure distribution along gas passages during current interruption, are not well known. In this paper, pressure rise, mass flow, and temperature calculations were carried out using a new calculation model, which takes mechanical compression by puffer piston, nozzle ablation in the nozzle throat and arc energy into consideration. By analysis of the calculation results, we found the pressure rise mechanism is as follows. While fixed contact located in the divergent part of nozzle, all of the ablation gas generated from the nozzle wall cannot be exhausted from the nozzle and it leads to high-pressure generation in the nozzle throat. This pressure causes transfer of hot ablation gas back to the puffer chamber via gas passage. The puffer pressure increases thermally due to temperature rise by this mechanism. At a longer arcing time, as high puffer pressure was already established in the puffer chamber, the nozzle ablation gas cannot flow back to the puffer chamber. Besides as mass flow through nozzle is limited by low gas density, the puffer pressure rise is obtained by the mechanical compression of puffer piston.
Introduction to the Special Issue: Commemorating Guilford's 1950 Presidential Address

This entire issue of the Creativity Research Journal (CRJ) is devoted to the work of J. P. Guilford. In addition to the two introductions, this issue contains theoretical articles honoring Guilford, followed by empirical investigations that use his ideas or techniques. Some of the empirical articles were not prepared specifically for this issue; they nonetheless honor Guilford by showing his impact on the field of creative studies. Guilford’s (1950) presidential address to the American Psychological Association often is credited with initiating the empirical research on creativity. As Plucker (2000–2001) points out in the second introduction to this special issue, Guilford himself spread the credit out to others working in the field and to the sociocultural context. Indeed, many important empirical efforts preceded Guilford’s. One historical review of creative studies was presented by Albert and Runco (1999). Becker (1995) described the 19th-century antecedents to creative studies. Most recently, Runco (1999) presented a chronology of events and publications that have somehow each been significant for creativity research. Even with numerous earlier efforts, Guilford (1950) himself did a great deal for this field. He argued cogently that we should study creativity, for example, and gave us techniques that could be used to do so. His work was so influential that, although he often is given a great deal of credit, at the same time he also is probably cited less than he should be. He is one of those persons whose work is a staple, and as such it is often taken for granted (and uncited). Consider in this regard his work on divergent thinking. He really pushed this line of work along—although, again, to be perfectly accurate there were earlier empirical studies of divergent thinking (reviewed by Runco, in press)—but Guilford sometimes is not cited in investigations that use measures adapted from his early work. Historiometricians realize that this sometimes happens: Citations are not always a good indicator of impact, because some people are so well known that they are sometimes mentioned but not cited. Guilford is of that stature in creative studies. The work on divergent thinking is represented in the second half of this issue. Be forewarned: A few articles commemorating Guilford will appear in the next issue. I also expect that Guilford’s ideas and work will be cited, discussed, applied, and honored for a long time to come, in CRJ and elsewhere.
Optimal Hyperparameters for Deep LSTM-Networks for Sequence Labeling Tasks

Selecting optimal parameters for a neural network architecture can often make the difference between mediocre and state-of-the-art performance. However, little is published which parameters and design choices should be evaluated or selected making the correct hyperparameter optimization often a “black art that requires expert experiences” (Snoek et al., 2012). In this paper, we evaluate the importance of different network design choices and hyperparameters for five common linguistic sequence tagging tasks (POS, Chunking, NER, Entity Recognition, and Event Detection). We evaluated over 50.000 different setups and found, that some parameters, like the pre-trained word embeddings or the last layer of the network, have a large impact on the performance, while other parameters, for example the number of LSTM layers or the number of recurrent units, are of minor importance. We give a recommendation on a configuration that performs well among different tasks. The optimized implementation of our BiLSTM-CRF architecture is publicly available.1 This publication explains in detail the experimental setup and discusses the results. A condensed version of this paper was presented at EMNLP 2017 (Reimers and Gurevych, 2017).2
Ayahuasca as Antidepressant ? Psychedelics and Styles of Reasoning in

There is a growing interest among scientists and the lay public alike in using the South American psychedelic brew, ayahuasca, to treat psychiatric disorders like depression and anxiety. Such a practice is controversial due to a style of reasoning within conventional psychiatry that sees psychedelic-induced modified states of consciousness as pathological. This article analyzes the academic literature on ayahuasca’s psychological effects to determine how this style of reasoning is shaping formal scientific discourse on ayahuasca’s therapeutic potential as a treatment for depression and anxiety. Findings from these publications suggest that different kinds of experiments are differentially affected by this style of reasoning but can nonetheless indicate some potential therapeutic utility of the ayahuasca-induced modified state of consciousness. The article concludes by suggesting ways in which conventional psychiatry’s dominant style of reasoning about psychedelic modified states of consciousness could be reconsidered. k e yword s : ayahuasca, psychedelic, hallucinogen, psychiatry, depression