LLukas22/scidocs huggingface dataset:
An Industrial Survey of Safety Evidence Change Impact Analysis Practice

Context. In many application domains, critical systems must comply with safety standards. This involves gathering safety evidence in the form of artefacts such as safety analyses, system specifications, and testing results. These artefacts can evolve during a system's lifecycle, creating a need for change impact analysis to guarantee that system safety and compliance are not jeopardised. Objective. We aim to provide new insights into how safety evidence change impact analysis is addressed in practice. The knowledge about this activity is limited despite the extensive research that has been conducted on change impact analysis and on safety evidence management. Method. We conducted an industrial survey on the circumstances under which safety evidence change impact analysis is addressed, the tool support used, and the challenges faced. Results. We obtained 97 valid responses representing 16 application domains, 28 countries, and 47 safety standards. The respondents had most often performed safety evidence change impact analysis during system development, from system specifications, and fully manually. No commercial change impact analysis tool was reported as used for all artefact types and insufficient tool support was the most frequent challenge. Conclusion. The results suggest that the different artefact types used as safety evidence co-evolve. In addition, the evolution of safety cases should probably be better managed, the level of automation in safety evidence change impact analysis is low, and the state of the practice can benefit from over 20 improvement areas.
A fuzzy inference system with application to player selection and team formation in multi-player sports

The success or failure of any team lies in the skills and abilities of the players that comprise the team. The process of player selection and team formation in multi-player sports is a complex multi-criteria problem where the ultimate success is determined by how the collection of individual players forms an effective team. In general, the selection of soccer players and formation of a team are judgments made by the coaches on the basis of the best available information. Very few structured and analytical models have been developed to support coaches in this effort. We propose a two-phase framework for player selection and team formation in soccer. The first phase evaluates the alternative players with a fuzzy ranking method and selects the top performers for inclusion in the team. The second phase evaluates the alternative combinations of the selected players with a Fuzzy Inference System (FIS) and selects the best combinations for team formation. A case study is used to illustrate the performance of the proposed approach. 2012 Sport Management Association of Australia and New Zealand. Published by Elsevier Ltd. All rights reserved.
Deficient Emotional Self-Regulation in Adults With Attention-Deficit / Hyperactivity Disorder ( ADHD ) : The Relative Contributions of Emotional Impulsiveness and ADHD Symptoms to Adaptive Impairments in Major Life Activities

Background: Recent reviews have argued that emotional impulsiveness (EI) and deficient emotional selfregulation are central components in attention-deficit/hyperactivity disorder (ADHD), not merely associated features or the consequence of comorbidity. Objectives: Our study has 2 aims: (1) to determine the frequency/severity of EI in adults with ADHD relative to these control groups; and (2) to evaluate the degree to which EI contributed to impairment in various domains of major life activities beyond that made by severity of the traditional 2 dimensions of ADHD (inattention, hyperactivity-impulsivity). Methods: We examined the frequency and severity of problems with EI in 3 groups: adults with ADHD (n = 146), clinical-control adults not diagnosed with ADHD (n = 97), and a community-control group (n = 109). Selfand other ratings of EI were utilized. Results: Results indicated that adults with ADHD had significantly more EI than either clinical or community controls, whether by selfor other reports, and whether symptoms were studied individually or in total. We also evaluated the extent to which EI contributed to the prediction of global ratings of selfand other rated impairments in 10 different domains beyond the contribution made by the traditional 2 dimensions of ADHD symptoms. EI uniquely contributed to 6 of 10 domains and overall impairment. We then evaluated this issue using more detailed measures of occupational impairment, educational history, criminal history, adverse driving outcomes, marital satisfaction, parenting stress, and offspring severity of ADHD, oppositional defiant disorder, and conduct disorder. Severity of EI independently contributed to most measures of impairment beyond severity of the 2 ADHD symptom dimensions and, in many cases, was the only predictor of some impairments. Conclusions: Our results indicate that EI is as central a component of ADHD as are its 2 traditional symptom dimensions. EI severity is not merely redundant with the other ADHD symptom dimensions, but adds additional explanatory and predictive power to understanding various forms of adult impairment. (J ADHD Relat Disord. 2010;1[4]:5–28) © 2010 Excerpta Medica.
Localizome: a server for identifying transmembrane topologies and TM helices of eukaryotic proteins utilizing domain information

The Localizome server predicts the transmembrane (TM) helix number and TM topology of a user-supplied eukaryotic protein and presents the result as an intuitive graphic representation. It utilizes hmmpfam to detect the presence of Pfam domains and a prediction algorithm, Phobius, to predict the TM helices. The results are combined and checked against the TM topology rules stored in a protein domain database called LocaloDom. LocaloDom is a curated database that contains TM topologies and TM helix numbers of known protein domains. It was constructed from Pfam domains combined with Swiss-Prot annotations and Phobius predictions. The Localizome server corrects the combined results of the user sequence to conform to the rules stored in LocaloDom. Compared with other programs, this server showed the highest accuracy for TM topology prediction: for soluble proteins, the accuracy and coverage were 99 and 75%, respectively, while for TM protein domain regions, they were 96 and 68%, respectively. With a graphical representation of TM topology and TM helix positions with the domain units, the Localizome server is a highly accurate and comprehensive information source for subcellular localization for soluble proteins as well as membrane proteins. The Localizome server can be found at http://localizome.org/.
Selective recognition of acetate ion by perimidinium-based receptors

Abstract The first perimidinium-based receptors 1 and 2 have been designed and synthesized. The anion binding properties of the receptors were evaluated in DMSO by UV–vis, fluorescence spectroscopy, and 1 H NMR methods. The results demonstrate that both receptors 1 and 2 exhibit good selectivity to acetate. The (C–H) + ⋯X − type ionic hydrogen bonding between the perimidinium moieties and acetate is the key interaction for the recognition.
Assessment of exposure to Leptospira serovars in veterinary staff and dog owners in contact with infected dogs.

OBJECTIVE
To assess patterns of seroreactivity to Leptospira serovars in veterinary professional staff and dog owners exposed to dogs with acute leptospirosis and to contrast these patterns in people with those observed in dogs.


DESIGN
Cross-sectional study.


SAMPLE POPULATION
Human subjects consisted of 91 people (50 veterinarians, 19 technical staff, 9 administrative personnel, and 13 dog owners) exposed to dogs with leptospirosis. Canine subjects consisted of 52 dogs with naturally occurring leptospirosis admitted to the University of Bern Vetsuisse Faculty Small Animal Clinic in 2007 and 2008.


PROCEDURES
People were tested for seroreactivity to regionally prevalent Leptospira serovars by use of a complement fixation test. A questionnaire designed to identify risk factors associated with seropositivity was used to collect demographic information from each study participant. Dogs were tested for seroreactivity to Leptospira serovars by use of a microscopic agglutination test.


RESULTS
On the basis of microscopic agglutination test results, infected dogs were seropositive for antibodies against Leptospira serovars as follows (in descending order): Bratislava (43/52 [83%]), Australis (43/52 [83%]), Grippotyphosa (18/52 [35%]), Pomona (12/52 [23%]), Autumnalis (6/52 [12%]), Icterohemorrhagiae (4/52 [8%]), Tarassovi (2/52 [4%]), and Canicola (1/52 [2%]). All 91 people were seronegative for antibodies against Leptospira serovars. Therefore, statistical evaluation of risk factors and comparison of patterns of seroreactivity to Leptospira serovars between human and canine subjects were limited to theoretical risks.


CONCLUSIONS AND CLINICAL RELEVANCE
Seroreactivity to Leptospira serovars among veterinary staff adhering to standard hygiene protocols and pet owners exposed to dogs with acute leptospirosis was uncommon.
PeerSpace - An Online Collaborative Learning Environment for Computer Science Students

The aim of Peer Space is to promote peer support and peer learning in introductory Computer Science (CS) courses by providing the students with online collaborative tools for convenient synchronous and asynchronous interactions on course related topics and social matters. This paper presents the development of various social and learning components in Peer Space that are unique in promoting collaborative learning. Analysis of preliminary results is presented.
High-frequency MAV state estimation using low-cost inertial and optical flow measurement units

This paper develops a simple and low-cost method for 3D, high-rate vehicle state estimation, specially designed for free-flying Micro Aerial Vehicles (MAVs). We fuse observations from inertial measurement units and the recently appeared low-cost optical flow smart cameras. These smart cameras integrate a sonar altimeter, a triaxial gyrometer and an optical flow sensor, and directly provide metric ego-motion information in the form of body velocities and altitude. Compared to state-of-the-art visual-inertial odometry methods, we are able to drastically reduce the computational load in the main processor unit, and obtain an accurate estimation of the vehicle state at a high update rate of 100Hz. We thus extend the current use of these smart cameras from hovering purposes to odometry estimation. In order to propose a simple algorithmic solution, we investigate the performances of two Kalman filters, in the extended and error-state flavors, alongside a large number of algorithm variations, using simulations and real experiments with precise ground-truth. We observe that the marginal performance gain attained with these algorithm improvements does not pay for the effort of implementing them. We conclude that a classical EKF in its simplest form is sufficient for providing motion estimates that coherently exploit the available measurements.
Introduction to Lewis Carroll's Through the Looking-Glass and The Hunting of the Snark in Narrative Analysis and Interpretation.

HE READING which will follow settles down without making any bones about it inside Carroll's text, taking advantage of the remarkable work of clearing the ground which has been accomplished by other people. Whoever wants to survey the territory completely, to be informed about the different biographical, critical, phenomenological, and structural aspects of the work of Lewis Carroll, should refer to the publications of Jean Gattegno and Gilles Deleuze.1
Associations of the FTO rs9939609 and the MC4R rs17782313 polymorphisms with type 2 diabetes are modulated by diet, being higher when adherence to the Mediterranean diet pattern is low

BACKGROUND
Although the fat mass and obesity (FTO) and melanocortin-4 receptor (MC4R) genes have been consistently associated with obesity risk, the association between the obesity-risk alleles with type 2 diabetes is still controversial. In some recent meta-analyses in which significant results have been reported, the associations disappeared after adjustment for body mass index (BMI). However gene-diet interactions with dietary patterns have not been investigated. Our main aim was to analyze whether these associations are modulated by the level of adherence to the Mediterranean Diet (MedDiet).


METHODS
Case-control study in 7,052 high cardiovascular risk subjects (3,430 type 2 diabetes cases and 3,622 non-diabetic subjects) with no differences in BMI. Diet was assessed by validated questionnaires. FTO-rs9939609 and MC4R-rs17782313 were determined. An aggregate genetic score was calculated to test additive effects. Gene-diet interactions were analyzed.


RESULTS
Neither of the polymorphisms was associated with type 2 diabetes in the whole population. However, we found consistent gene-diet interactions with adherence to the MedDiet both for the FTO-rs9939609 (P-interaction=0.039), the MC4R-rs17782313 (P-interaction=0.009) and for their aggregate score (P-interaction=0.006). When adherence to the MedDiet was low, carriers of the variant alleles had higher type 2 diabetes risk (OR=1.21, 95%CI: 1.03-1.40; P=0.019 for FTO-rs9939609 and OR=1.17, 95%CI:1.01-1.36; P=0.035 for MC4R-rs17782313) than wild-type subjects. However, when adherence to the MedDiet was high, these associations disappeared (OR=0.97, 95%CI: 0.85-1.16; P=0.673 for FTO-rs9939609 and OR=0.89, 95%CI:0.78-1.02; P=0.097 for MC4R-rs17782313). These gene-diet interactions remained significant even after adjustment for BMI. As MedDiet is rich in folate, we also specifically examined folate intake and detected statistically significant interaction effects on fasting plasma glucose concentrations in non-diabetic subjects. However these findings should be interpreted with caution because folate intake may simply reflect a healthy dietary pattern.


CONCLUSIONS
These novel results suggest that the association of the FTO-rs9939609 and the MC4R-rs17782313 polymorphisms with type 2 diabetes depends on diet and that a high adherence to the MedDiet counteracts the genetic predisposition.
A NOVEL RECTANGULAR SLOT ANTENNA WITH EMBEDDED SELF-SIMILAR T-SHAPED STRIPS FOR WLAN APPLICATIONS

A novel rectangular slot antenna with embedded selfsimilar strips is proposed for wireless local area network (WLAN) applications. The proposed antenna comprises a T-shaped monopole and inverted self-similar strips embedded in the rectangular slot etched on the ground plane. The measured results of the fabricated antenna show that the impedance bandwidths (VSWR < 2) are 180 MHz from 2.36 to 2.54 GHz and 920 MHz from 5.05 to 5.97GHz, which cover all the 2.4/5.2/5.8 GHz WLAN operating bands. And the radiation patterns are almost omni-directional in the azimuthal plane within the lower operating bands.
Structural phase change in Co2.25Fe0.75O4 spinel oxide by vacuum annealing and role of coexisting CoO phase on magnetic properties

Abstract The spinel oxide Co 2.25 Fe 0.75 O 4 has been prepared by co-precipitation route. The as prepared material has been annealed at 800 °C under vacuum. Properties of the samples annealed under vacuum have been compared with the sample annealed in air. Synchrotron X-ray diffraction, Raman spectroscopy and X-ray absorption near edge structure spectroscopy have been used for structural phase characterization. The cubic spinel structure in air annealed sample has been splitted into Co and Fe rich phases. The Co rich spinel phase has transformed into Cobalt monoxide (CoO) after vacuum annealing. This has resulted an increase of Fe:Co ratio in the Fe rich spinel phase. Raman spectra indicated a transformation of the distribution of Co and Fe ions from normal spinel like structure for the sample annealed in air to mixed spinel structure for the samples annealed under vacuum. The existence tetravalent Fe 4+ ion has been confirmed in all the samples and it is new information for Co doped spinel ferrite system. All the samples exhibited ferrimagnetic behavior and exchange bias effect. The focus point is that vacuum annealing has been used as an effective route of material processing to control the structural phase and also, enhancement of magnetic properties in Co rich ferrite.
Somatic mutations in MYD88 and CXCR4 are determinants of clinical presentation and overall survival in Waldenstrom macroglobulinemia.

Whole genome sequencing has revealed activating somatic mutations in MYD88 (L265P) and CXCR4 in Waldenström macroglobulinemia (WM). CXCR4 somatic mutations in WM are the first ever reported in human cancer and are similar to nonsense (NS) and frameshift (FS) germline mutations found in warts, hypogammaglobulinemia, infections and myelokathexis (WHIM) syndrome. We genotyped lymphoplasmacytic cells from 175 WM patients and observed significantly higher bone marrow (BM) disease involvement, serum immunoglobulin-M levels, and symptomatic disease requiring therapy, including hyperviscosity syndrome in those patients with MYD88(L265P)CXCR4(WHIM/NS) mutations (P < .03). Patients with MYD88(L265P)CXCR4(WHIM/FS) or MYD88(L265P)CXCR4(WILDTYPE (WT)) had intermediate BM and serum immunoglobulin-M levels; those with MYD88(WT)CXCR4(WT) showed lowest BM disease burden. Fewer patients with MYD88(L265P) and CXCR4(WHIM/FS or NS) vs MYD88(L265P)CXCR4(WT) presented with adenopathy (P < .01), further delineating differences in disease tropism based on CXCR4 status. Neither MYD88 nor CXCR4 mutations correlated with SDF-1a (RS1801157) polymorphisms in 54 patients who were genotyped for these variants. Unexpectedly, risk of death was not impacted by CXCR4 mutation status, but by MYD88(WT) status (hazard ratio 10.54; 95% confidence interval 2.4-46.2, P = .0018). Somatic mutations in MYD88 and CXCR4 are important determinants of clinical presentation and impact overall survival in WM. Targeted therapies directed against MYD88 and/or CXCR4 signaling may provide a personalized treatment approach to WM.
A Robust Density-Based Clustering Approach Using DBCURE – MapReduce Techniques

Clustering is the process of grouping similar data into clusters and dissimilar data into different clusters. Density-based clustering is a useful clustering approach such as DBSCAN and OPTICS. The increasing volume of data and varying size of data sets lead the clustering process challenging. So that we propose a parallel framework of clustering with advanced approach called MapReduce. We develop a new algorithm DBCURE which is modified from DBSCAN. Next we propose a newly developed parallel algorithm called DBCURE-MR that is DBCURE algorithm is parallelized with MapReduce framework. This proposed method finds clusters in parallel manner efficiently. Keywords— MapReduce, DBCURE, density based clustering, parallelization algorithm.
NCRP Report No. 160, Ionizing Radiation Exposure of the Population of the United States, medical exposure--are we doing less with more, and is there a role for health physicists?

IN 2006, Americans were exposed to more than seven times as much ionizing radiation from medical procedures as was the case in the early 1980’s, according to a new report on population exposure released March 3, 2009, by the National Council on Radiation Protection and Measurements (NCRP) at its annual meeting in Bethesda, Maryland. In 2006, medical exposure constituted nearly half of the total radiation exposure of the U.S. population from all sources. The increase was primarily a result of the growth in the use of medical imaging procedures, explained Kenneth R. Kase, senior vice president of NCRP and chairman of the scientific committee that produced the report. “The increase was due mostly to the higher utilization of computed tomography (CT) and nuclear medicine. These two imaging modalities alone contributed 36 percent of the total radiation exposure and 75 percent of the medical radiation exposure of the U.S. population.” The number of CT scans and nuclear medicine procedures performed in the United States during 2006 was estimated to be 67 million and 18 million, respectively. NCRP Report No. 160, Ionizing Radiation Exposure of the Population of the United States, provides a complete review of all radiation exposures for 2006. The following Fig. 1 and Table 1 summarize the changes that have occurred from the 1980’s to 2006. Some causes and consequences of this significant increase in medical radiation exposure are the focus of this editorial. According to James Thrall, chairman of the American College of Radiology’s Board of Chancellors and Radiology at Massachusetts General Hospital, “Imaging has literally become the guiding hand of medical practice.”
Controlled Atmosphere Storage and Aminoethoxyvinylglycine Postharvest Dip Delay Post Cold Storage Softening of `Snow King' Peach

‘Snow King’ peaches (Prunus persica) harvested at commercial maturity were subjected to different carbon dioxide (CO2) and oxygen (O2) atmosphere combinations for a 2-week simulated transportation [0 °C (32 °F)] period after 1 week of cold storage in air (0 °C). In 1998, air or 5%, 10%, 15%, or 20% CO2 combined with 3% or 6% O2 were used during shipment. The trial was repeated in 1999, but for this year half of the fruit were treated with a 50 mg·L–1 (ppm) aminoethoxyvinylglycine (AVG) postharvest dip before storage and simulated shipment. In addition, O2 levels during simulated shipment were reduced to 1.5% and 3%. At harvest and after the 2-week simulated shipment, fruit flesh firmness, soluble solids concentration (SSC), titratable acidity (TA), and chilling injury (CI) were evaluated. For both years, there were no significant differences in quality attributes among the different treatments after the simulated shipment period. SSC and TA did not change during 5 days postshipment ripening at 20 °C (68 °F). In 1998 all treatments softened rapidly during the postshipment ripening at 20 °C, and were ready to eat [13 N (1 N = 0.225 lb force)] after 3 days. In 1999, both the high CO2 atmospheres during shipment and the AVG postharvest dip slowed the rate of softening during subsequent ripening at 20 °C. With respect to fruit softening, there was significant interaction between storage atmosphere and AVG treatment. AVGtreated fruit shipped under a 20% CO2 + 3% O2 atmosphere did not soften to the transfer point (firmness = 27 N) within our 5-day ripening period, while fruit not treated with AVG and shipped under the same atmosphere softened to the transfer point in 3 days. Control fruit (no AVG + air shipment) softened to the transfer point in 2 days. Our previous work found that when white flesh peaches soften to less than 27 N firmness they become very susceptible to impact bruise injury during retail distribution. We call this critical level of fruit flesh firmness the transfer point. Symptoms of CI, low O2, or high CO2 injury were not observed in any treatment in either year.