LLukas22/scidocs huggingface dataset:
Integration of Cloud computing and Internet of Things: A survey

Cloud computing and Internet of Things (IoT) are two very different technologies that are both already part of our life. Their adoption and use is expected to be more and more pervasive, making them important components of the Future Internet. A novel paradigm where Cloud and IoT are merged together is foreseen as disruptive and as an enabler of a large number of application scenarios. In this paper, we focus our attention on the integration of Cloud and IoT, which is what we call the CloudIoT paradigm. Many works in literature have surveyed Cloud and IoT separately and, more precisely, their main properties, features, underlying technologies, and open issues. However, to the best of our knowledge, these works lack a detailed analysis of the new CloudIoT paradigm, which involves completely new applications, challenges, and research issues. To bridge this gap, in this paper we provide a literature survey on the integration of Cloud and IoT. Starting by analyzing the basics of both IoT and Cloud Computing, we discuss their complementarity, detailing what is currently driving to their integration. Thanks to the adoption of the CloudIoT paradigm a number of applications are gaining momentum: we provide an up-to-date picture of CloudIoT applications in literature, with a focus on their specific research challenges. These challenges are then analyzed in details to show where the main body of research is currently heading. We also discuss what is already available in terms of platforms – both proprietary and open source – and projects implementing the CloudIoT paradigm. Finally, we identify open issues and future directions in this field, which we expect to play a leading role in the landscape of the Future Internet. Preprint submitted to Journal of Future Generation Computer SystemsSeptember 14, 2015 *Manuscript Click here to view linked References
Effects of radiation on levels of DNA damage in normal non-adjacent mucosa from colorectal cancer cases.

PURPOSE
Defects in DNA repair pathways have been linked with colorectal cancer (CRC). Adjuvant radiotherapy has become commonplace in the treatment of rectal cancer however it is associated with a higher rate of second cancer formation. It is known that radiation results in DNA damage directly or indirectly by radiation-induced bystander effect (RIBE) by causing double-strand breaks (DSBs). The majority of work in RIBE has been performed in cell lines and limited studies have been in or ex vivo.


METHODS
The first study aim was to examine by immunohistochemistry, levels of DSB (expression of the protein MRE11) in normal colonic tissue outside the irradiated field post neo-adjuvant radiotherapy (group 1). These levels were compared to (a) irradiated tumour tissue post neo-adjuvant radiation within the same group, (b) a CRC patient group (group 2) who had not undergone neo-adjuvant radiotherapy and (c) a non-cancer patient group (group 3). The second aim was to determine if MRE11 expression levels were related to survival or radio-sensitivity post neo-adjuvant radiotherapy.


RESULTS
There was a highly significant increase in MRE 11 expression in group 1 versus groups 2 and 3 (p < 0.001). There was no association between MRE11 levels and survival or radio-sensitivity.


CONCLUSION
Our findings show radiotherapy causes DSBs at significantly higher levels in normal colonic mucosa of patients post neo-adjuvant treatment which may represent RIBE. If this damage remains unrepaired, increased levels of genomic instability may contribute to the higher occurrence of second cancers in patients treated post neo-adjuvant radiotherapy.
Comparison of pre- vs. postmeal administration of miglitol for 3 months in type 2 diabetic patients.

AIM
alpha-Glucosidase inhibitors (alphaGIs) primarily modify postprandial plasma glucose levels and should be taken just before meals. We previously demonstrated that a single administration of miglitol within 30 min after the start of a meal was equally effective as when administered just before a meal. We here compared pre- vs. postmeal administration of miglitol for 3 months in type 2 diabetic patients.


METHODS
Thirty-one type 2 diabetic outpatients who had never been treated with insulin injections or alphaGIs were randomized to two groups: patients in group A were asked to take miglitol just before meals, while patients in group B were asked to take miglitol after meals. We measured 1,5-anhydroglucitol (1,5-AG) and HbA(1C) levels in these patients.


RESULTS
The administration of miglitol after meals for a 3-month period decreased HbA(1C) and increased 1,5-AG levels to the same extent as when administered just before meals. The incidence of adverse effects seemed to be unrelated to the timing of the miglitol administration.


CONCLUSIONS
Our results suggest that if patients have difficulty remembering to take miglitol just before meal, they should be instructed to take the medicine together with other medicine(s) after the meal; this instruction may improve the treatment compliance of diabetic patients.
Three-dimensional optical holography using a plasmonic metasurface

• Users may freely distribute the URL that is used to identify this publication. • Users may download and/or print one copy of the publication from the University of Birmingham research portal for the purpose of private study or non-commercial research. • User may use extracts from the document in line with the concept of ‘fair dealing’ under the Copyright, Designs and Patents Act 1988 (?) • Users may not further distribute the material nor use it for the purposes of commercial gain.
Achieving chronic kidney disease treatment targets in renal transplant recipients: results from a cross-sectional study in Spain.

BACKGROUND
Kidney transplant recipients are considered to have chronic kidney disease (CKD) irrespective of glomerular filtration rate (GFR) or presence or absence of markers of kidney damage. The aim of this work was to investigate the prevalence of CKD-stages and whether the guidelines for general population (Kidney Disease Outcomes Quality Initiative) are routinely followed in kidney transplant in Spain.


PATIENTS AND METHODS
Two thousand one hundred sixty renal transplant recipients followed up at the outpatient clinics in 4 University Hospitals were included. The estimated GFR (eGFR) was calculated according to the abbreviated modification of diet in renal disease equation, and the patients were classified following the Kidney Disease Outcomes Quality Initiative stages.


RESULTS
Chronic kidney failure (eGFR <60 mL/min/1.73 m) was present in 1505 patients (69.7%), 54.4% were 3T-stage (eGFR 30-59); 13.0% were 4T-stage (eGFR 15-30), and 2.3% were 5T-stage. The prevalence of severe anemia increased from 4.1% in 1T-stage to 44% in 5T-stage (P=0.000) as did the percentage of patients on erythropoiesis-stimulating agents from 1.3% to 68% (P=0.000). The intact parathyroid hormone levels increased as graft function declined and 45% of 5T-stage patients had intact parathyroid hormone levels more than 300. Calcium and vitamin D supplements were administered to 50% and 40% of patients, respectively. Hypertension was quite common and increased with the progression of CKD. The mean total cholesterol was 192+/-39 mg/dL, and the levels did not increase with the decline in graft function. Approximately 60% had suboptimal cholesterol despite 50% being on statins treatment.


CONCLUSIONS
CKD and their complications were prevalent in renal transplant recipients. The control of some of these complications is far below targets established for nontransplant CKD patients despite a progressive intensification of therapy as graft function declines.
Suicidal ideation in pregnancy: assessment and clinical implications

The objectives of this study were 1) to determine the prevalence of suicidal ideation (SI) in pregnant women with a history of neuropsychiatric illness, 2) to assess the relative sensitivity of commonly used depression rating scales for detecting SI, and 3) to examine the sociodemographic and clinical predictors of SI in pregnant women. Demographic data, Beck Depression Inventory [BDI] and Hamilton Rating Scale for Depression [HRSD] questionnaires, and SCID interviews were obtained from 383 pregnant women presenting to the Emory Women’s Mental Health Program or the Emory Women’s Epilepsy Program. Among those who completed both scales, 29.2% endorsed SI on the BDI and 16.9% on the HRSD, with 33.0% endorsing SI on at least one of the rating scales and 13.1% on both rating scales. The rate of SI endorsement on the BDI was 73.3% higher than the HRSD. Multivariate logistic regression demonstrated that SI in pregnant women was associated with unplanned pregnancy (OR = 2.97), current major depression (OR = 4.12), and comorbid anxiety disorder (OR = 4.17). Further studies are warranted to identify additional predictors of perinatal suicidality and to clarify the nature of the association between such factors and the presence of SI in pregnant women.
Text mining and natural language processing: introduction for the special issue

This paper provides an introduction to this special issue of SIGKDD Explorations devoted to Natural Language Processing and Text Mining.
Research Paper: Use of SNOMED CT to Represent Clinical Research Data: A Semantic Characterization of Data Items on Case Report Forms in Vasculitis Research

OBJECTIVE
To estimate the coverage provided by SNOMED CT for clinical research concepts represented by the items on case report forms (CRFs), as well as the semantic nature of those concepts relevant to post-coordination methods.


DESIGN
Convenience samples from CRFs developed by rheumatologists conducting several longitudinal, observational studies of vasculitis were selected. A total of 17 CRFs were used as the basis of analysis for this study, from which a total set of 616 (unique) items were identified. Each unique data item was classified as either a clinical finding or procedure. The items were coded by the presence and nature of SNOMED CT coverage and classified into semantic types by 2 coders.


MEASUREMENTS
Basic frequency analysis was conducted to determine levels of coverage provided by SNOMED CT. Estimates of coverage by various semantic characterizations were estimated.


RESULTS
Most of the core clinical concepts (88%) from these clinical research data items were covered by SNOMED CT; however, far fewer of the concepts were fully covered (that is, where all aspects of the CRF item could be represented completely without post-coordination; 23%). In addition, a large majority of the concepts (83%) required post-coordination, either to clarify context (e.g., time) or to better capture complex clinical concepts (e.g., disease-related findings). For just over one third of the sampled CRF data items, both types of post-coordination were necessary to fully represent the meaning of the item.


CONCLUSION
SNOMED CT appears well-suited for representing a variety of clinical concepts, yet is less suited for representing the full amount of information collected on CRFs.
Formal Specification and Verification of Distributed Systems

Computations of distributed systems are extremely difficult to specify and verify using traditional techniques because the systems are inherently concurrent, asynchronous, and nondeterministic. Furthermore, computing nodes in a distributed system may be highly independent of each other, and the entire system may lack an accurate global clock.
Forecasting Exchange Rates : a Comparative Analysis Vincenzo Pacelli

This research aims to analyze and to compare the ability of different mathematical models, such as artificial neural networks (ANN) and ARCH and GARCH models, to forecast the daily exchange rates Euro/U.S. dollar (USD), identifying which, among all the models applied, produces more accurate forecasts. By empirically comparing the different mathematical models developed in this research, the traditional indicators for assessing the relevance of the models show that the ARCH and GARCH models, especially in their static formulations, are better than the ANN for analyzing and forecasting the dynamics of the exchange rates. JEL Classification: C3, C5, G14, G20.
Characterization of test functions in CKS-space

We prove a characterization theorem for the test functions in a CKS-space. Some crucial ideas concerning the growth condition are given.
Automatic Audio Content Analysis

This paper describes the theoretic framework and applications of automatic audio content analysis. After explaining the basic properties of audio analysis, we present a toolbox being the basis for the development of audio analysis algorithms. We also describe new applications which can be developed using the toolset, among them music indexing and retrieval as well as violence detection in the sound track of videos.
Predicted indirectly recognizable HLA epitopes presented by HLA-DR correlate with the de novo development of donor-specific HLA IgG antibodies after kidney transplantation.

BACKGROUND
HLA class-I mismatches selectively induce antibody formation after kidney transplantation. The de novo development of donor-specific IgG HLA class-I antibodies may be dependent on the HLA class-II background of the patient by presenting T-helper epitopes within the recognized HLA class-I antigens.


METHODS
The correlation between antibody production against mismatched donor human leukocyte antigens (HLA) class I and the number of HLA class II-restricted predicted indirectly recognizable HLA epitopes (PIRCHE-II) in the respective HLA class-I mismatches was investigated. To this end, we analyzed sera taken after nephrectomy from a cohort of 21 non-immunized individuals that received a renal transplant.


RESULTS
Fourty-nine HLA class-I mismatches were found which all contained immunogenic eplets according to HLAMatchmaker. Donor specific HLA antibody responses were detected against 38 HLA class-I mismatches after nephrectomy. These mismatches were found to contain a larger number of PIRCHE-II when compared to mismatches which did not induce donor specific HLA antibodies. Most PIRCHE-II (68%) were not part of an eplet as defined by HLAMatchmaker.


CONCLUSIONS
Our data suggest that presentation of donor-derived HLA class-I peptides by recipient HLA class-II molecules plays a significant role in de novo development of donor-specific IgG HLA antibodies.
The HASYv2 dataset

This paper describes the HASY dataset of handwritten symbols. HASY is a publicly available, free of charge dataset of single symbols similar to MNIST. It contains 168 233 instances of 369 classes. HASY contains two challenges: A classification challenge with 10 pre-defined folds for 10-fold cross-validation and a verification challenge.
Three Knowledge Management Strategies: Knowledge Hierarchies, Knowledge Markets, and Knowledge Communities

1 Bob Zmud was the accepting Senior Editor for this article. 2 Much research has been done on organizational forms, particularly hierarchies, communities, and markets. A classic article that describes how firms can be organized is Ouchi, W. G., “Markets, Bureaucracies, and Clans,” Administrative Science Quarterly (25), 1980, pp. 129-141. Three more recent articles that examine the use of markets, hierarchies, and communities that are internal to the firm are Adler, P. S., “Market, Hierarchy, and Trust: The Knowledge Economy and the Future of Capitalism,” Organization Science (12:2), 2001, pp. 214-234; Barney, J. B., “Firm Resources and Sustained Competitive Advantage,” Journal of Management (17), 1991, pp. 99-120; and Conner, K. R. and Prahalad, C. K., “A Resource-based Theory of the Firm: Knowledge Versus Opportunism,” Organization Science (7:5), 1996, pp. 477-501. 3 Note that we use the term “reuse” because our focus is the knowledge management strategy rather than the user per se. 4 Alavi, M. and Leidner, D. E., “Knowledge Management and Knowledge Management Systems: Conceptual Foundations and Research Issues,” MIS Quarterly (25:1), 2001, pp. 107-136; Conner and Prahalad, op. cit.; Grant, R. M., “Prospering in Dynamically Competitive Environments: Organizational Capability as Knowledge Integration,” THREE KNOWLEDGE MANAGEMENT STRATEGIES: KNOWLEDGE HIERARCHIES, KNOWLEDGE MARKETS, AND KNOWLEDGE COMMUNITIES
¿Ciudadanía postpolítica? El legadoliberal y la despolitización

Resumen es: El trabajo toma como punto de partida la despolitizacion y asfixia de la vida civica en las sociedades occidentales contemporaneas, y sugiere que para ...
Global Sourcing, Multiple Country-of-Origin Facets, and Consumer Reactions

It has seldom examined how global sourcing decisions affect consumer formulate the hypotheses empirically tested in this study. Next, we describe the methodology employed to test the behavior. Through an experimental design, this study investigated how global sourcing locations and related factors influence consumers’ product hypotheses. Last, we present our findings and discuss the implications of our research. evaluations in various quality dimensions. Our findings have interesting
Combining genetic markers and clinical risk factors improves the risk assessment of impaired glucose metabolism.

BACKGROUND
Although several candidate gene polymorphisms (SNPs) have been associated with increased risk of type 2 diabetes mellitus (T2DM), relatively few studies have assessed the ability of T2DM candidate genes to assess the risk of impaired fasting glucose (IFG), impaired glucose tolerance (IGT), and T2DM beyond the information provided by clinical risk factors.


OBJECTIVE
To test whether the inclusion of genetic markers in a regression model provides a better assessment of the risk of IFG, IGT, and T2DM than a model based only on non-genetic risk factors commonly assessed in clinical settings.


METHODS
Subjects (n = 485; 213 parents, 272 offspring) from the Quebec Family Study, not known to haveT2DM, were measured for several risk factors and underwent an oral glucose tolerance test. Thirty-eight SNPs in 25 susceptibility/ candidate genes previously reported to be associated with T2DM were genotyped. In order to identify risk factors associated with IFG/IGT/T2DM, two logistic regression models were tested: a full model (FM) including age, sex, body mass index (BMI), systolic and diastolic blood pressure, smoking status, and the 38 SNPs; and a reduced model (RM), in which the SNPs were dropped, which allowed us to test the null-hypothesis that the markers are not associated with the risk of IFG/IGT/T2DM. Performances of the models were compared by using a likelihood ratio test and the receiver-operating characteristic curves (ROC).The area under the curve (AUC) was calculated from the ROC curve.


RESULTS
The analyses showed that age (P < 0.0001), BMI (P < 0.0001), and six variants (IGF2BP2 rs4402960, P = 0.002; ADIPOQ+276 G>T, P = 0.004; UCP2Ala55Val, P = 0.01; CDKN2AI2B rs3731201, P = 0.02; rs495490, P = 0.02, and rsl 0811661, P = 0.03) were significantly associated with the risk of IFG/IGT/T2DM. Dropping genetic markers from the analysis significantly reduced the fit of the model to the data (chi-square = 38.98, P < 0.00001 contrasting RM to FM), suggesting that the genetic markers are significantly associated with the risk of IFG/IGT/T2DM. Furthermore, the AUC was higher for FM than for RM (0.85 (95% CI 0.81-0.89) versus 0.81 (95% CI 0.76-0.85), P = 0.004).


CONCLUSION
Our results suggest that combining genetic markers with traditional clinical risk factors has the potential to improve our ability to assess the risk of complex diseases such as T2DM.
Measuring Stroke Impact with SIS: Construct Validity of SIS Telephone Administration

Objectives: The purpose of this study was to examine the construct validity of the Stroke Impact Scale (SIS) using telephone mode of administration. Methods: Stroke patients were identified using national VA administrative data and ICD-9 codes in 13 participating VA hospitals. Stroke was confirmed by reviewing electronic medical records. Patients were administered SIS by telephone at 12-weeks post-stroke, and administered the Functional Independence Measure (FIM) and SF-36V at 16 weeks post-stroke. The instrument’s convergent validity and its ability to differentiate between groups of stroke patients with different disability levels were examined using Pearson’s correlations and Kruskal–Wallis one way ANOVA tests. Results: All the relevant relationships yielded high correlation coefficients with statistical significance: 0.86 for FIM-motor vs. SIS-ADL, and 0.77 for PF in SF-36V vs. SIS-PHYSICAL. The SIS presented better score discrimination and distribution for different severity of stroke than FIM and SF-36V without severe ceiling and floor effects. Kruskal–Wallis tests showed the Physical Component Score of SF-36V did not discriminate any disability levels. Physical functioning (PF) in SF-36V, FIM-motor, SIS-PHYSICAL, SIS-16, and SIS-ADL showed better discrimination in person’s functioning. The pairwise comparisons showed that SIS-PHYSICAL, SIS-16, and SIS-ADL discriminated more Rankin levels than FIM-motor and PF in SF-36V. Conclusions: SIS telephone survey had superior convergent validity and was better at differentiating between groups of stroke patients with different disability levels than the FIM and SF-36V with no evidence of ceiling and floor effects. Telephone administration of SIS would be a useful and cost-effective method to follow-up community dwelling veterans with stroke.
Long-range hot-carrier transport in hybrid perovskites visualized by ultrafast microscopy

The Shockley-Queisser limit for solar cell efficiency can be overcome if hot carriers can be harvested before they thermalize. Recently, carrier cooling time up to 100 picoseconds was observed in hybrid perovskites, but it is unclear whether these long-lived hot carriers can migrate long distance for efficient collection. We report direct visualization of hot-carrier migration in methylammonium lead iodide (CH3NH3PbI3) thin films by ultrafast transient absorption microscopy, demonstrating three distinct transport regimes. Quasiballistic transport was observed to correlate with excess kinetic energy, resulting in up to 230 nanometers transport distance that could overcome grain boundaries. The nonequilibrium transport persisted over tens of picoseconds and ~600 nanometers before reaching the diffusive transport limit. These results suggest potential applications of hot-carrier devices based on hybrid perovskites.
Expatriate performance management: The case of Nokia Telecommunications

Today’s world-class companies such as Nokia employ effective employee performance management (PM) practices. They have realized that seeking sustaining competitive advantage from the effective management of human resources is of utmost importance. Until today, however, there has existed little understanding about how these companies manage the performance of their critical personnel group, the expatriate employees. A key finding of the case study of Nokia Telecommunications is that the performance of different types of expatriates in varying situations is, and should be, managed dissimilarly. Reflecting this finding, it is suggested that companies should develop alternative PM tools. © 2000 John Wiley & Sons, Inc.