LLukas22/scidocs huggingface dataset:
Towards a model of postglacial biogeography in shallow marine species along the Patagonian Province: lessons from the limpet Nacella magellanica (Gmelin, 1791)

Patagonia extends for more than 84,000 km of irregular coasts is an area especially apt to evaluate how historic and contemporary processes influence the distribution and connectivity of shallow marine benthic organisms. The true limpet Nacella magellanica has a wide distribution in this province and represents a suitable model to infer the Quaternary glacial legacy on marine benthic organisms. This species inhabits ice-free rocky ecosystems, has a narrow bathymetric range and consequently should have been severely affected by recurrent glacial cycles during the Quaternary. We performed phylogeographic and demographic analyses of N. magellanica from 14 localities along its distribution in Pacific Patagonia, Atlantic Patagonia, and the Falkland/Malvinas Islands. Mitochondrial (COI) DNA analyses of 357 individuals of N. magellanica revealed an absence of genetic differentiation in the species with a single genetic unit along Pacific Patagonia. However, we detected significant genetic differences among three main groups named Pacific Patagonia, Atlantic Patagonia and Falkland/Malvinas Islands. Migration rate estimations indicated asymmetrical gene flow, primarily from Pacific Patagonia to Atlantic Patagonia (Nem=2.21) and the Falkland/Malvinas Islands (Nem=16.6). Demographic reconstruction in Pacific Patagonia suggests a recent recolonization process (< 10 ka) supported by neutrality tests, mismatch distribution and the median-joining haplotype genealogy. Absence of genetic structure, a single dominant haplotype, lack of correlation between geographic and genetic distance, high estimated migration rates and the signal of recent demographic growth represent a large body of evidence supporting the hypothesis of rapid postglacial expansion in this species in Pacific Patagonia. This expansion could have been sustained by larval dispersal following the main current system in this area. Lower levels of genetic diversity in inland sea areas suggest that fjords and channels represent the areas most recently colonized by the species. Hence recolonization seems to follow a west to east direction to areas that were progressively deglaciated. Significant genetic differences among Pacific, Atlantic and Falkland/Malvinas Islands populations may be also explained through disparities in their respective glaciological and geological histories. The Falkland/Malvinas Islands, more than representing a glacial refugium for the species, seems to constitute a sink area considering the strong asymmetric gene flow detected from Pacific to Atlantic sectors. These results suggest that historical and contemporary processes represent the main factors shaping the modern biogeography of most shallow marine benthic invertebrates inhabiting the Patagonian Province.
The association of Chinese hospital work environment with nurse burnout, job satisfaction, and intention to leave.

The purpose of this study was to describe nurse burnout, job satisfaction, and intention to leave and to explore the relationship of work environment to nursing outcomes in a sample of 9,698 nurses from 181 hospitals in China. Nurses reported moderate levels of emotional exhaustion and depersonalization and high levels of reduced personal accomplishment. Nearly one-fifth of the nurses reported high levels of burnout on all three dimensions. Forty-five percent of the nurses were dissatisfied with their current job; these nurses were most dissatisfied with their salary. Five percent of nurses reported an intention to leave. Nurses reporting mixed and good work environments were less likely to report high burnout, job dissatisfaction, and intention to leave compared with those in poor work environments. The results suggest that high burnout and low job satisfaction are prominent problems for Chinese nurses, and improving work environment might be an effective strategy for better nursing outcomes in Chinese hospitals.
Supporting recovery in patients with psychosis through care by community-based adult mental health teams (REFOCUS): a multisite, cluster, randomised, controlled trial.

BACKGROUND
Mental health policy in many countries is oriented around recovery, but the evidence base for service-level recovery-promotion interventions is lacking.


METHODS
We did a cluster, randomised, controlled trial in two National Health Service Trusts in England. REFOCUS is a 1-year team-level intervention targeting staff behaviour to increase focus on values, preferences, strengths, and goals of patients with psychosis, and staff-patient relationships, through coaching and partnership. Between April, 2011, and May, 2012, community-based adult mental health teams were randomly allocated to provide usual treatment plus REFOCUS or usual treatment alone (control). Baseline and 1-year follow-up outcomes were assessed in randomly selected patients. The primary outcome was recovery and was assessed with the Questionnaire about Processes of Recovery (QPR). We also calculated overall service costs. We used multiple imputation to estimate missing data, and the imputation model captured clustering at the team level. Analysis was by intention to treat. This trial is registered, number ISRCTN02507940.


FINDINGS
14 teams were included in the REFOCUS group and 13 in the control group. Outcomes were assessed in 403 patients (88% of the target sample) at baseline and in 297 at 1 year. Mean QPR total scores did not differ between the two groups (REFOCUS group 40·6 [SD 10·1] vs control 40·0 [10·2], adjusted difference 0·68, 95% CI -1·7 to 3·1, p=0·58). High team participation was associated with higher staff-rated scores for recovery-promotion behaviour change (adjusted difference -0·4, 95% CI -0·7 to -0·2, p=0·001) and patient-rated QPR interpersonal scores (-1·6, -2·7 to -0·5, p=0·005) at follow-up than low participation. Patients treated in the REFOCUS group incurred £1062 (95% CI -1103 to 3017) lower adjusted costs than those in the control group.


INTERPRETATION
Although the primary endpoint was negative, supporting recovery might, from the staff perspective, improve functioning and reduce needs. Implementation of REFOCUS could increase staff recovery-promotion behaviours and improve patient-rated recovery.


FUNDING
National Institute for Health Research.
Treating onychomycosis.

Onychomycosis accounts for one third of fungal skin infections. Because only about one half of nail dystrophies are caused by fungus, the diagnosis should be confirmed by potassium hydroxide preparation, culture or histology before treatment is started. Newer, more effective antifungal agents have made treating onychomycosis easier. Terbinafine and itraconazole are the therapeutic agents of choice. Although the U.S. Food and Drug Administration has not labeled fluconazole for the treatment of onychomycosis, early efficacy data are promising. Continuous oral terbinafine therapy is most effective against dermatophytes, which are responsible for the majority of onychomycosis cases. Intermittent pulse dosing with itraconazole is as safe and effective as short-term continuous therapy but more economical and convenient. With careful monitoring, patients treated with the newer antifungal agents have a good chance of achieving relief from onychomycosis and its complications.
Concurrent use of complementary and alternative medicine with antiretroviral therapy reduces adherence to HIV medications.

OBJECTIVE
Antiretroviral therapy requires strict adherence to ensure therapeutic success. Concurrent use of complementary and alternative medicine (CAM) could alter the adherence to and thereby effectiveness of antiretroviral drugs. This study examined the association of CAM use with adherence to antiretroviral therapy (ART) and CD4 count.


METHODS
The study was conducted in two HIV clinics: one in a semi-urban, the other in a rural area. Adherence to ART was assessed using the Morisky Medication Adherence Scale (MMAS). Data on type of CAM used and MMAS adherence were collected by patient interview and demographic; clinical data were collected from hospital records.


RESULTS
Altogether 212 HIV patients participated in the exit study conducted over 3 months. Almost half (47.9%) used CAM concurrently with antiretroviral drugs. Dietary supplements (40.3%), healing systems (36.5%) and exercise (23.2%) were mainly used. The use of CAM significantly lowered adherence to ART (89.4% in non-CAM users versus 82.5% in CAM users, P = 0.01). Improvement in CD4 count was less in patients using CAM compared to non-CAM users although the difference was not statistically significant (310.5 ± 294.0 cells/L in CAM users versus 224.5 ± 220.0 cells/L in non-CAM users, P = 0.13). Patients attending the rural HIV clinic were more likely to use CAM compared to patients attending semi-urban hospital (χ(2) test = 7.0; P < 0.01).


CONCLUSION
Use of CAM could lower adherence to antiretroviral therapy. There is need to develop protocol which could help in monitoring CAM use in HIV patients especially those from rural settings.
Psychological effects of the intensified follow-up of the CEAwatch trial after treatment for colorectal cancer

BACKGROUND
The aim of the study was to evaluate psychological effects of the state-of-art intensified follow-up protocol for colorectal cancer patients in the CEAwatch trial.


METHOD
At two time points during the CEAwatch trial questionnaires regarding patients' attitude towards follow-up, patients' psychological functioning and patients' experiences and expectations were sent to participants by post. Linear mixed models were fitted to assess the influences and secular trends of the intensified follow-up on patients' attitude towards follow-up and psychological functioning. As secondary outcome, odds ratios were calculated using ordinal logistic mixed model to compare patients' experiences to their expectations, as well as their experiences at two different time points.


RESULTS
No statistical significant effects of the intensified follow-up were found on patients' attitude towards the follow-up and psychological functioning variables. Patients had high expectations of the intensified follow-up and their experiences at the second time point were more positive compared to the scores at the first time point.


CONCLUSION
The intensified follow-up protocol posed no adverse effects on patients' attitude towards follow-up and psychological functioning. In general, patients were more nervous and anxious at the start of the new follow-up protocol, had high expectations of the new follow-up protocol and were troubled by the nuisances of the blood sample testing. As they spent more time in the follow-up and became more adapted to it, the nervousness and anxiety decreased and the preference for the frequent blood test became high in replacement of conversations with the doctors.
Combining Low-Level and Summary Representations of Opinions for Multi-Perspective Question Answering

While much recent progress has been made in research on fact-based question answering, our work aims to extend question-answering research in a different direction — to handle multi-perspective question-answering tasks, i.e. question-answering tasks that require an ability to find and organize opinions in text. In particular, this paper proposes an approach to multi-perspective question answering that views the task as one of opinion-oriented information extraction. We first describe an annotation scheme developed for the low-level representation of opinions, and note the results of interannotator agreement studies using the opinion-based annotation framework. Next, we propose the use of opinion-oriented “scenario templates” to act as a summary representation of the opinions expressed in a document, a set of documents, or an arbitrary text segment. Finally, we outline an approach for the automatic construction of opinion-based summary representations and describe how they might be used to support a variety of multi-perspective question answering tasks.
Colon cancer screening, lifestyle, and risk of colon cancer

Objectives: Sigmoidoscopy screening and fecal occult blood (FOB) tests have been demonstrated as effective ways to reduce mortality from colorectal cancer. However, most studies of colorectal cancer screening and cancer mortality have not taken into consideration lifestyle factors that could account for the observed associations. The purpose of this study was to determine the association between screening and incidence of colon cancer, taking into consideration important lifestyle factors. Methods: We estimated the association between screening and colon cancer after taking into consideration health and lifestyle factors using data obtained as part of population-based case–control study of incident colon cancers. Results: Sigmoidoscopy screening, especially as part of a checkup, was protective against incident colon cancer in both men (OR 0.56, 95% CI 0.44–0.77) and women (OR 0.53, 95% CI 0.33–0.77) after adjusting for other risk factors for colon cancer. For men, associations were stronger for distal tumors (OR 0.48, 95% CI 0.31–0.71) than for proximal tumors (OR 0.67, 95% CI 0.45–1.11). We did not observe significant associations between FOB test and colon cancer. Differences in characteristics between those who were screened and not screened were also observed. Men were more likely to report having a sigmoidoscopy as part of a checkup than were women, as were people with higher levels of education. People who reported having a sigmoidoscopy as part of a checkup also reported eating diets lower in fat and higher in fiber, folate, and vegetables. Men were more likely to report higher levels of physical activity, and women were more likely to report taking hormone replacement therapy (HRT) if they also reported a sigmoidoscopy. Both men and women who reported a sigmoidoscopy for screening purposes were more likely to have a family history of colorectal cancer. Conclusions: These data provide additional support for the benefits of having a screening sigmoidoscopy. The associations between screening sigmoidoscopy and colon cancer do not appear to be the result of lifestyle factors.
Sensitization to inhalant allergens between 4 and 8 years of age is a dynamic process: results from the BAMSE birth cohort

BACKGROUND
There is limited knowledge of the development of IgE-antibody levels over time in childhood, with respect to persistency and co-sensitization to specific inhalant allergens.


METHODS
Data from 2033 children participating in the BAMSE birth cohort was used. Background factors and clinical parameters were obtained and IgE antibody (ab) levels to eight common airborne allergens were measured (>or=0.35 kU(A)/L) when the children were 4 and 8 years of age.


RESULTS
Between 4 and 8 years the proportion of children sensitized to any of the inhalant allergens tested increased from 15% to 25%. At 4 years IgE-ab to birch and cat dominated, whereas at the age of 8, there was a considerable increase in the proportion of sensitization to timothy and dog. Except for mites and moulds, IgE-ab levels to all aeroallergens increased significantly between 4 and 8 years among those already sensitized at 4. Transient sensitization to inhalant allergen was uncommon. Furthermore, sensitization to birch pollen at 4 years increased the risk for becoming sensitized to timothy, cat and dog later in life. Such an association was not observed among those sensitized primarily to animal dander.


CONCLUSIONS
There is a prominent process of sensitization at pre-school age to inhalant allergens, and in Northern Europe sensitization to birch pollen early in life seems to be important for this process. Such a process has a probable impact on the development of allergic disease in the growing child.
Pad porosity , compressibility and slurry delivery effects in chemical-mechanical planarization : modeling and experiments

A chemical-mechanical planarization (CMP) model based on lubrication theory is developed which accounts for pad compressibility, pad porosity and means of slurry delivery. Slurry ®lm thickness and velocity distributions between the pad and the wafer are predicted using the model. Two regimes of CMP operation are described: the lubrication regime (for ,40±70 mm slurry ®lm thickness) and the contact regime (for thinner ®lms). These regimes are identi®ed for two different pads using experimental copper CMP data and the predictions of the model. The removal rate correlation based on lubrication and mass transport theory agrees well with our experimental data in the lubrication regime. q 2000 Elsevier Science S.A. All rights reserved.
The effect of ISO 14001 certification announcements on stock performance

Purpose: This study aspires to explore how the United States stock market reacts to ISO 14001 certification announcements. Design/methodology/approach: The manuscript employs an event-study methodology on a sample of 140 announcements and matching control firms to study the impact of ISO 14001 certification announcements. Findings: Our results suggest that ISO 14001 certification announcements have a negative impact on stock performance. More importantly, it shows that the shareholder wealth reduced due to these certifications announcements. Research limitations/implications: This study focuses on short-term stock market reaction. Future studies should consider the entire sample of ISO 14001 certified firms within the US and use certification date to evaluate short-term as well as long-term improvements in shareholder wealth. Practical implications: Our results suggest that firms will need to educate shareholders about their actions towards the betterment of the environment. Such coordinated communication will ensure that the ISO 14001 standard is highly regarded, widely adopted, and even requested by shareholders. Originality/value: Past empirical studies indicate that certified EMSs help organizations to reduce waste and pollution, thereby ultimately resulting in superior environmental and economic performance. At the same time, given its focus on the process rather than performance outcomes, opponents criticize ISO 14001 suggesting that it is just a label for image-building. Due to this dilemma, it is pertinent to evaluate how shareholders perceive a firm’s attainment of ISO 14001 certification announcements.
Comparison of the effects of low-dose rosuvastatin on plasma levels of cholesterol and oxidized low-density lipoprotein in 3 ultracentrifugally separated low-density lipoprotein subfractions.

BACKGROUND
Plasma-oxidized (ox) low-density lipoprotein (LDL) is an atherogenic lipoprotein. The distribution of ox-LDL in plasma LDL subfractions and the effect of statins on this distribution have not been investigated in detail.


OBJECTIVE
We examined the distribution of cholesterol and ox-LDL in 3 ultracentrifugally separated plasma LDL subfractions and investigated the effects of a statin, rosuvastatin, on the levels of these lipoproteins.


MATERIALS AND METHODS
Thirty-one polygenic hypercholesterolemic subjects were included in this study. Levels of cholesterol and ox-LDL in 3 plasma LDL subfractions and plasma levels of remnant-like particle cholesterol, ox-LDL, and adiponectin were measured after 0, 3, 6, and 12 months of treatment with rosuvastatin. Sequential ultracentrifugation was performed to subfractionate plasma lipoproteins.


RESULTS
The mean daily dose of rosuvastatin over the 12 months of treatment was 2.9 ± 1.0 mg (mean ± standard deviation). The cholesterol subfraction distribution was 43 ± 10% as low-density LDL, 46 ± 8% as medium-density LDL, and 13 ± 5% as high-density LDL. Similarly, the distribution of ox-LDL was 31 ± 10% as low-density LDL, 48 ± 7% as medium-density LDL, and 22 ± 8% as high-density LDL. After 12 months of treatment with rosuvastatin, the level of cholesterol was significantly reduced in all 3 subfractions (P < .0001), as was the level of ox-LDL (P < .0001). Furthermore, the plasma cholesterol level in high-density lipoprotein2 increased significantly.


CONCLUSIONS
The distribution of ox-LDL in plasma LDL subfractions was more skewed toward the denser subfractions, compared with cholesterol. Rosuvastatin treatment significantly reduced plasma levels of cholesterol and ox-LDL in all LDL subfractions.
A framework of mobile transaction use : the user's perspective

.....................................................................................................................................II ACKNOWLEDGEMENTS .......................................................................................................... IV DEDICATION.................................................................................................................................. V TABLE OF CONTENTS .............................................................................................................. VI LIST OF FIGURES ...................................................................................................................... XII LIST OF TABLES ...................................................................................................................... XIII CHAPTER
Quantum Detection Theory for the Free-Space Channel

The fundamental performance limits of optical communications over the freespace channel are developed using quantum theory, and presented in terms of concepts familiar to communications engineers. The compact Dirac notation generally employed in quantum mechanics is defined, and key concepts necessary for understanding quantum projection measurements are reviewed. A derivation that provides significant insights into the quantum measurement performed by the optimum receiver is developed by interpreting the familiar technique of photon counting in terms of quantum projection operators. The performance of the optimum quantum receiver for on–off keying and optical binary phase-shift-keying (BPSK) modulation is treated first as a noise-free (or pure-state) problem, then extended to include the effects of background radiation. The performance of the optimum quantum receiver is compared to that of classical optical receivers employing photon-counting and coherent detection techniques, and it is shown to be exponentially better in most cases.
Social networking of the Smart Home

Social networking on the Web has become an integral part of our lives. Merging of computing with physical things enabled the conversion of everyday objects into information appliances. This merging allows Smart Homes to offer new automation possibilities to their residents. We propose utilizing existing social networking infrastructures and their Web-based APIs in order to integrate Smart Homes to the Web, offering social status to physical devices. We exploit the functionality and the Web 2.0 technologies provided by Facebook to transform the interaction with the Smart Home into a shared, social experience. A preliminary technical evaluation indicates that our approach is feasible and it offers acceptable performance.
Mini-MAC: Raising the bar for vehicular security with a lightweight message authentication protocol

Article history: Received 31 October 2016 Received in revised form 4 May 2017 Accepted 5 July 2017 Available online xxxx