LLukas22/scidocs huggingface dataset:
Powering a Ventricular Assist Device (VAD) With the Free-Range Resonant Electrical Energy Delivery (FREE-D) System

Wireless data communication technology has eliminated wired connections for data transfer to portable devices. Wireless power technology offers the possibility of eliminating the remaining wired connection: the power cord. For ventricular assist devices (VADs), wireless power technology will eliminate the complications and infections caused by the percutaneous wired power connection. Integrating wireless power technology into VADs will enable VAD implants to become a more viable option for heart failure patients (of which there are 80 000 in the United States each year) than heart transplants. Previous transcutaneous energy transfer systems (TETS) have attempted to wirelessly power VADs ; however, TETS-based technologies are limited in range to a few millimeters, do not tolerate angular misalignment, and suffer from poor efficiency. The free-range resonant electrical delivery (FREE-D) wireless power system aims to use magnetically coupled resonators to efficiently transfer power across a distance to a VAD implanted in the human body, and to provide robustness to geometric changes. Multiple resonator configurations are implemented to improve the range and efficiency of wireless power transmission to both a commercially available axial pump and a VentrAssist centrifugal pump [3]. An adaptive frequency tuning method allows for maximum power transfer efficiency for nearly any angular orientation over a range of separation distances. Additionally, laboratory results show the continuous operation of both pumps using the FREE-D system with a wireless power transfer efficiency upwards of 90%.
Adherence to Antihypertensive Medication in Treatment-Resistant Hypertension Undergoing Renal Denervation.

BACKGROUND
Adherence to medication has been repeatedly proposed to represent a major cause of treatment-resistant hypertension (TRH); however, treatment decisions such as treating TRH with renal denervation depend on accurate judgment of adherence. We carefully analyzed adherence rates to medication before and after renal denervation and its effect on blood pressure (BP) control.


METHODS AND RESULTS
Eighty patients with TRH were included in 2 prospective observational studies that assessed the difference of potential antihypertensive and nephroprotective effects of renal denervation. To compare prescribed with actual medication intake (representing a measure of adherence), we analyzed urine samples collected at baseline and at 6 months after renal denervation for antihypertensive compounds or metabolites (by liquid chromatography-mass spectrometry). In addition to office BP, 24-hour ambulatory BP and central hemodynamics (central systolic pressure, central pulse pressure) were assessed. Informed consent for analyses of urine metabolites was obtained from 79 of 80 patients. Actual intake of all antihypertensive drugs was detected at baseline and at 6 months after renal denervation in 44 (56%) and 52 (66%) patients, respectively; 1 drug was missing in 22 (28%) and 17 (22%) patients, respectively, and ≥2 drugs were missing in 13 (16%) and 10 (13%) patients, respectively. At baseline, 24-hour ambulatory BP (P=0.049) and central systolic BP (P=0.012) were higher in nonadherent patients. Adherence did not significantly change overall (McNemar-Bowker test, P=0.362). An increase in adherence was observed in 21 patients, and a decrease was observed in 11 patients. The decrease in 24-hour ambulatory BP was not different in those with stable adherence 6 months after renal denervation (n=41, -7±13 mm Hg) compared with those with increased adherence (n=21, -10±13 mm Hg) and decreased adherence (n=11, -7±14 mm Hg) (P>0.20). Our study is limited by the relatively small sample size and potentially by the specific health environment of our university center (Northern Bavaria, Germany).


CONCLUSIONS
Nonadherence to medication among patients with TRH was relatively low: ≈1 of 6 patients with TRH did not take ≥2 of the prescribed drugs. Adherence pattern did not change significantly after renal denervation and had no impact on the overall observed BP changes, supporting the concept that renal denervation is an effective treatment in patients with TRH.


CLINICAL TRIAL REGISTRATION
URL: https://www.clinicaltrials.gov. Unique identifiers: NCT00888433, NCT01442883 and NCT01687725.
Acute hepatitis B in a healthcare worker: a case report of genuine vaccination failure.

BACKGROUND
Individuals who reach the antibody threshold level of 10IU/l against the surface protein of the hepatitis B virus (HBV) after completion of a series of hepatitis B vaccination are considered to be long-term protected against a clinically manifest HBV infection.


CASE REPORT
Here we describe an acute hepatitis B infection in a patient who received five hepatitis B vaccinations. Although his initial response to vaccination was moderate, he finally reached an excellent hepatitis B surface antibody level (anti-HBs) titres of more than 1000 IU/l in response to a booster vaccination with a recombinant DNA vaccine. Nevertheless, he developed full-blown acute hepatitis due to an HBV infection 14years after this booster vaccination. A DNA analysis of the surface protein encoding region followed by phylogenetic analysis showed that our patient was infected with a normal HBV strain that is circulating among men who have sex with men. To our knowledge, this is the first report of a genuine hepatitis B vaccination failure in someone who acquired a high anti-HBs level in response to a recombinant DNA hepatitis B vaccine.


CONCLUSION
Healthcare workers whose response to the initial hepatitis B vaccination is moderate might be vulnerable to hepatitis B virus infection.
A quantum particle swarm optimization

The particle swarm optimization algorithm is a new methodology in evolutionary computation. It has been found to be extremely effective is solving a wide range of engineering problems, however, it is of low efficiency in dealing with the discrete problems. In this paper, a new discrete particle swarm optimization algorithm based on quantum individual is proposed. It is simpler and more powerful than the algorithms available. The simulation experiments and its application in the CDMA also prove its high efficiency.
A Communications-Oriented Perspective on Traffic Management Systems for Smart Cities: Challenges and Innovative Approaches

The growing size of cities and increasing population mobility have determined a rapid increase in the number of vehicles on the roads, which has resulted in many challenges for road traffic management authorities in relation to traffic congestion, accidents, and air pollution. Over the recent years, researchers from both industry and academia have been focusing their efforts on exploiting the advances in sensing, communication, and dynamic adaptive technologies to make the existing road traffic management systems (TMSs) more efficient to cope with the aforementioned issues in future smart cities. However, these efforts are still insufficient to build a reliable and secure TMS that can handle the foreseeable rise of population and vehicles in smart cities. In this survey, we present an up-to-date review of the different technologies used in the different phases involved in a TMS and discuss the potential use of smart cars and social media to enable fast and more accurate traffic congestion detection and mitigation. We also provide a thorough study of the security threats that may jeopardize the efficiency of the TMS and endanger drivers' lives. Furthermore, the most significant and recent European and worldwide projects dealing with traffic congestion issues are briefly discussed to highlight their contribution to the advancement of smart transportation. Finally, we discuss some open challenges and present our own vision to develop robust TMSs for future smart cities.
A high-resolution CMOS time-to-digital converter utilizing a Vernier delay line

This paper describes a CMOS time-to-digital converter (TDC) integrated circuit utilizing tapped delay lines. A technique that allows the achievement of high resolution with low dead-time is presented, The technique is based on a Vernier delay line (VDL) used in conjunction with an asynchronous read-out circuitry. A delay-locked loop (DLL) is used to stabilize the resolution against process variations and ambient conditions. A test circuit fabricated in a standard 0.7-/spl mu/m digital CMOS process is presented. The TDC contains 128 delay stages and achieves 30-ps resolution, stabilized by the DLL, with the accuracy exceeding /spl plusmn/1 LSB. Test results show that even higher resolutions can be achieved using the VDL method, and resolutions down to 5 ps are demonstrated to be obtainable.
Proximal diversion at the time of ileal pouch-anal anastomosis for ulcerative colitis: current practices of North American colorectal surgeons.

PURPOSE
Pelvic sepsis is a serious complication after ileal pouch-anal anastomosis for ulcerative colitis that may lead to pouch failure or poor function. Although a temporary loop ileostomy may be created at the time of ileal pouch-anal anastomosis to prevent or minimize the consequences of an anastomotic leak, research has suggested that an ileostomy can be safely omitted in selected patients. The purpose of this study was to examine the use of proximal diversion by colorectal surgeons at the time of ileal pouch-anal anastomosis for ulcerative colitis.


METHODS
A questionnaire was mailed to all practicing fellows of The American Society of Colon and Rectal Surgeons in North America. Surgeons were asked to describe their typical practice for a number of clinical scenarios.


RESULTS
Questionnaires were mailed to 913 American Society of Colon and Rectal Surgeons fellows, and 63 percent responded. For a patient who has had a prior colectomy and is not taking steroids, 27 percent of surgeons would perform ileal pouch-anal anastomosis alone, and 73 percent would perform ileal pouch-anal anastomosis with a loop ileostomy. For a patient who has not had previous surgery and is taking prednisone 40 mg/day, 16 percent of surgeons would perform a subtotal colectomy with an end ileostomy, 82 percent would perform a total proctocolectomy and ileal pouch-anal anastomosis with a loop ileostomy, and 2 percent would perform a total proctocolectomy and ileal pouch-anal anastomosis without an ileostomy. There was no relationship between practice setting, annual ileal pouch-anal anastomosis volume, or years in practice and surgeon response for either scenario.


CONCLUSIONS
The majority of surgeons create a temporary loop ileostomy at the time of ileal pouch-anal anastomosis for ulcerative colitis.
Introduction to the CoNLL-2003 Shared Task: Language-Independent Named Entity Recognition

We describe the CoNLL-2003 shared task: language-independent named entity recognition. We give background information on the data sets (English and German) and the evaluation method, present a general overview of the systems that have taken part in the task and discuss their performance.
Psychosocial correlates of mammography screening in older African American women.

PURPOSE/OBJECTIVES
To explore psychosocial correlates of older African American women's adherence to annual mammography screening, including cancer fatalism, dispositional optimism, social support, knowledge of breast cancer screening guidelines, perceptions of general health, and components of the Health Belief Model (HBM), and to examine factors associated with annual mammography screening.


DESIGN
Cross-sectional survey.


SETTING
Central North Carolina.


SAMPLE
198 African American women aged 50-98 years living in low-income housing.


METHODS
Women attended group sessions at low-income housing complexes and completed questionnaires. Differences between women who had or did not have a mammogram in the previous year were explored using correlate variables associated with the HBM. Stepwise multivariable regression models were fit to explore factors associated with social support and significant components of the HBM.


MAIN RESEARCH VARIABLES
Demographics, cancer fatalism, dispositional optimism, social support, perceptions of general health, components of the HBM, and mammography in the past year.


FINDINGS
The groups did not differ by age, education, marital status, having a friend or family member with breast cancer, ever having had a clinical breast examination, self-rated health, cancer fatalism, dispositional optimism, or feelings about the seriousness of and their susceptibility to breast cancer. The groups differed significantly on mammogram-related variables, how often women should have clinical breast examinations, benefits and barriers to mammography screening, and social support. Stepwise multivariable regression analyses showed that dispositional optimism and social support were related significantly to perception of benefits; education, dispositional optimism, and cancer fatalism were related to barriers; and dispositional optimism was related to social support.


CONCLUSIONS
Older, low-income, African American women have perceived barriers to cancer screening, educational and cancer knowledge detriments, and a lack of health-related social support that may decrease adherence to mammography screening.


IMPLICATIONS FOR NURSING
The next step is to develop culturally appropriate educational interventions that increase knowledge about breast cancer and screening guidelines, enhance health-related social support, and address barriers and perhaps cancer fatalism in older, low-income, African American women.
Socioeconomic determinants of dietary patterns in low- and middle-income countries: a systematic review.

BACKGROUND
In high-income countries, high socioeconomic status (SES) is generally associated with a healthier diet, but whether social differences in dietary intake are also present in low- and middle-income countries (LMICs) remains to be established.


OBJECTIVE
We performed a systematic review of studies that assessed the relation between SES and dietary intake in LMICs.


DESIGN
We carried out a systematic review of cohort and cross-sectional studies in adults in LMICs and published between 1996 and 2013. We assessed associations between markers of SES or urban and rural settings and dietary intake.


RESULTS
A total of 33 studies from 17 LMICs were included (5 low-income countries and 12 middle-income countries; 31 cross-sectional and 2 longitudinal studies). A majority of studies were conducted in Brazil (8), China (6), and Iran (4). High SES or living in urban areas was associated with higher intakes of calories; protein; total fat; cholesterol; polyunsaturated, saturated, and monounsaturated fatty acids; iron; and vitamins A and C and with lower intakes of carbohydrates and fiber. High SES was also associated with higher fruit and/or vegetable consumption, diet quality, and diversity. Although very few studies were performed in low-income countries, similar patterns were generally observed in both LMICs except for fruit intake, which was lower in urban than in rural areas in low-income countries.


CONCLUSIONS
In LMICs, high SES or living in urban areas is associated with overall healthier dietary patterns. However, it is also related to higher energy, cholesterol, and saturated fat intakes. Social inequalities in dietary intake should be considered in the prevention and control of noncommunicable diseases in LMICs.
Using Smart Edge IoT Devices for Safer, Rapid Response With Industry IoT Control Operations

The Internet of Things (IoT) offers the user seamless interoperability and connectivity between devices, systems, services, disparate networks, and in particular control systems. End users expect to connect quickly and transparently via any endpoint device, be it a phone, tablet, wearable, TV, car, or other system that is Internet enabled. Smart IoT devices can serve as versatile control system interfaces, allowing for rapid response and potentially ubiquitous access. However, these devices can present significant security challenges. Using these technologies for user access control at IoT endpoints is vulnerable to replay, man-in-the-middle, and denial-of-service attacks. This paper presents a model that combines the capabilities of smart IoT devices with control system gateways using real-time challenge response for secure control operations. The proposed solution using both endpoint and gateway devices employs a mix of compute, cryptography, signal/image processing, and communication capabilities for authentication and authorization functions. We propose a model that is more secure, scalable, and resilient with real-time performance as compared to traditional approaches. We also provide an example IoT architecture, by showing an overview of Intel's IoT framework for control system gateways currently deployed in control, manufacturing, transportation, and retail tracking environments.
Response to “ Neutropenic Events in Community Practices Reduced by First and Subsequent Cycle Pegfilgrastim Use ”

We read with interest the study by Ozer et al. [1]. However, several issues deserve further discussion or documentation, as follows. 1. Was it appropriate medical care for these patients to receive pegfilgrastim? The expected rate of febrile neutropenia (FN) was 8.2% based on registry data. The available guidelines at the time suggested a cutoff risk of about 40%, but these patients had good performance status and few comorbidities. No other data were presented to justify pegfilgrastim use. 2. Were patients informed of the benefits, risks, and alternatives when receiving pegfilgrastim, when the expected risk of FN was only 8.2%? G-CSFs are not harmless drugs. Bone pain is seen in up to one third of patients who receive G-CSF [2] and the odds ratio for bone pain is 2.9 from a meta-analysis [3]. There is also concern that these drugs may increase the risk for subsequent hematologic malignancies [4]. 3. Who paid for the pegfilgrastim, because it was used outside the national guidelines? The cost of this drug is substantial. If 2,202 patients received pegfilgrastim, for a median of 4.6 cycles, at a cost of $3,139 per injection (http://www.drugstore.com), the total cost of drug alone would be $31,795,559. Was the cost borne by the sponsor or by the patients and their insurers? Practicing oncologists should not conclude that the use of pegfilgrastim is indicated when the risk for FN is only 8% in patients with a good performance status and few comorbidities. This question can only be answered by a randomized clinical trial.
"Unresolving pneumonia" as the main manifestation of atypical Kawasaki disease.

Two cases of atypical Kawasaki disease (KD) manifested as persistent lobar lung consolidation, prolonged fever, and active inflammatory laboratory markers unresponsive to antibiotic treatment are reported. One of the children developed a giant coronary aneurysm. Atypical KD should be considered in the differential diagnosis of young children with prolonged fever and lobar consolidation unresponsive to antibiotics.
Wechsler Intelligence Scale for Children-fourth edition (WISC-IV) short-form validity: a comparison study in pediatric epilepsy.

PURPOSE
The purpose of this article was to investigate the accuracy of the WISC-IV short forms in estimating Full Scale Intelligence Quotient (FSIQ) and General Ability Index (GAI) in pediatric epilepsy.


METHODS
One hundred and four children with epilepsy completed the WISC-IV as part of a neuropsychological assessment at a tertiary-level children's hospital. The clinical accuracy of eight short forms was assessed in two ways: (a) accuracy within +/- 5 index points of FSIQ and (b) the clinical classification rate according to Wechsler conventions. The sample was further subdivided into low FSIQ (≤ 80) and high FSIQ (> 80).


RESULTS
All short forms were significantly correlated with FSIQ. Seven-subtest (Crawford et al. [2010] FSIQ) and 5-subtest (BdSiCdVcLn) short forms yielded the highest clinical accuracy rates (77%-89%). Overall, a 2-subtest (VcMr) short form yielded the lowest clinical classification rates for FSIQ (35%-63%). The short form yielding the most accurate estimate of GAI was VcSiMrBd (73%-84%).


CONCLUSIONS
Short forms show promise as useful estimates. The 7-subtest (Crawford et al., 2010) and 5-subtest (BdSiVcLnCd) short forms yielded the most accurate estimates of FSIQ. VcSiMrBd yielded the most accurate estimate of GAI. Clinical recommendations are provided for use of short forms in pediatric epilepsy.
Robotic versus manual control in magnetic steering of an endoscopic capsule.

BACKGROUND AND STUDY AIMS
Capsular endoscopy holds promise for the improved inspection of the gastrointestinal tract. However, this technique is limited by a lack of controlled capsule locomotion. Magnetic steering has been proposed by the main worldwide suppliers of commercial capsular endoscopes and by several research groups. The present study evaluates and discusses how robotics may improve diagnostic outcomes compared with manual magnetic steering of an endoscopic capsule.


MATERIALS AND METHODS
An endoscopic capsule prototype incorporating permanent magnets was deployed in an ex vivo colon segment. An operator controlled the external driving magnet manually or with robotic assistance. The capsule was maneuvered through the colon, visualizing and contacting targets installed on the colon wall. Procedure completion time and number of targets reached were collected for each trial to quantitatively compare manual versus robotic magnetic steering ( T-test analysis with P = 0.01). Then, through a set of in vivo animal trials, the efficacy of both approaches was qualitatively assessed.


RESULTS
In ex vivo conditions, robotic-assisted control was superior to manual control in terms of targets reached (87 % +/- 13 % vs 37 % +/- 14 %). Manual steering demonstrated faster trial completion time (201 +/- 24 seconds vs 423 +/- 48 seconds). Under in vivo conditions, the robotic approach confirmed higher precision of movement and better reliability compared with manual control.


CONCLUSIONS
Robotic control for magnetic steering of a capsular endoscope was demonstrated to be more precise and reliable than manual operation. Validation of the proposed robotic system paves the way for automation of capsular endoscopy and advanced endoscopic techniques.
A Prognostic Modeling Approach for Predicting Recurring Maintenance for Shipboard Propulsion Systems

Accurate prognostic models and associated algorithms that are capable of predicting future component failure rates or performance degradation rates for shipboard propulsion systems are critical for optimizing the timing of recurring maintenance actions. As part of the Naval maintenance philosophy on condition based maintenance (CBM), prognostic algorithms are being developed for gas turbine applications that utilize state-of-the-art probabilistic modeling and analysis technologies. NSWCCD-SSES Code 9334 has continued interest in investigating methods for implementing CBM algorithms to modify gas turbine preventative maintenance in such areas as internal crank wash, fuel nozzles and lube oil filter replacement. This paper will discuss a prognostic modeling approach developed for the LM2500 and Allison 501-K17 gas turbines based on the combination of probabilistic analysis and fouling test results obtained from NSWCCD in Philadelphia. In this application, the prognostic module is used to assess and predict compressor performance degradation rates due to salt deposit ingestion. From this information, the optimum time for on-line waterwashing or crank washing from a cost/benefit standpoint is determined.