LLukas22/scidocs huggingface dataset:
Queering Cult Cinema: Performances of Gendered Reception

“Gender” has been a commonly explored topic in the study of cult cinema, in particular with Joanne Hallows exploring “The masculinity of cult,” [1] and Ernest Mathijs and Jamie Sexton discussing gender and sexuality in their analysis of cult cinema. [2] However, there exists an unexplored gap between gender and queer studies in relation to cult cinema audiences, namely concerning performativity and audience participation. This presentation will explore how queer film audiences have developed performances of gender by “queering” films that are not originally or purposefully constituted as “queer.” This “queering” involves 1.) seeking performances of non-normative sexuality and 2.) recognising elements that might represent (or relate to) queer identities, subcultures, and aesthetics, such as camp and gender fluidity, even against the original intentions of the filmmakers. These films are queered to the point where a film’s reception might be altered and develop a cult status. Through this cult status comes performance and representation of gender or “performances of gendered reception” in the space/venue of the cinematic screening. In the reception of these queered films, the audience might respond and engage either through genuine reactions or performed reactions. These reactions and performances will be analysed in this presentation through textual readings of several “queered” cult film texts, juxtaposed with films initially intended as queer (or containing intentional queer elements). Some examples of these films where “queering” has occurred include The Wizard of Oz (1939), Calamity Jane (1953), Grey Gardens (1976), Mommie Dearest (1981), and Top Gun (1986). Intentionally queer films include The Rocky Horror Picture Show (1975), Pink Flamingos (1972), Paris is Burning (1990), and The Adventures of Priscilla, Queen of the Desert (1994). By analysing several of these texts, a clearer understanding will be developed between what constitutes performances of gender in cult cinema audiences, particularly in terms of what is genuine and what is intentionally performed. [1] Hollows, Joanne. "The Masculinity of Cult." In Defining Cult Movies: The Cultural Politics of Oppositional Taste , edited by Mark Jancovich, Antonio Lazaro Reboll, Julian Stringer, and Andy Willis, 35-53. Manchester: Manchester University Press, 2003. [2] Mathijs, Ernest, and Jamie Sexton. Cult Cinema: An Introduction . Chichester, West Sussex: Wiley-Blackwell, 2011.
Faster‐acting insulin aspart: earlier onset of appearance and greater early pharmacokinetic and pharmacodynamic effects than insulin aspart

AIMS
To evaluate the pharmacokinetics and pharmacodynamics of faster-acting insulin aspart and insulin aspart in a randomized, single-centre, double-blind study.


METHODS
Fifty-two patients with type 1 diabetes (mean age 40.3 years) received faster-acting insulin aspart, insulin aspart, or another faster aspart formulation (not selected for further development), each as a single 0.2 U/kg subcutaneous dose, under glucose-clamp conditions, in a three-way crossover design (3-12 days washout between dosing).


RESULTS
Faster-acting insulin aspart had a faster onset of exposure compared with insulin aspart, shown by a 57% earlier onset of appearance [4.9 vs 11.2 min; ratio 0.43, 95% confidence interval (CI) 0.36; 0.51], a 35% earlier time to reach 50% maximum concentration (20.7 vs 31.6 min; ratio 0.65, 95% CI 0.59; 0.72) and a greater early exposure within 90 min after dosing. The greatest difference occurred during the first 15 min, when area under the serum insulin aspart curve was 4.5-fold greater with faster-acting insulin aspart than with insulin aspart. Both treatments had a similar time to maximum concentration, total exposure and maximum concentration. Faster-acting insulin aspart had a significantly greater glucose-lowering effect within 90 min after dosing [largest difference: area under the curve for the glucose infusion rate (AUC(GIR), 0-30 min) ratio 1.48, 95% CI 1.13; 2.02] and 17% earlier time to reach 50% maximum glucose infusion rate (38.3 vs 46.1 min; ratio 0.83, 95% CI 0.73; 0.94). The primary endpoint (AUC(GIR, 0-2 h)) was 10% greater for faster-acting insulin aspart, but did not reach statistical significance (ratio 1.10, 95% CI 1.00; 1.22). Both treatments had similar total and maximum glucose-lowering effects, indicating similar overall potency.


CONCLUSIONS
Faster-acting insulin aspart was found to have earlier onset and higher early exposure than insulin aspart, and a greater early glucose-lowering effect, with similar potency.
LINKING MIND TO BRAIN: THE MATHEMATICS OF BIOLOGICAL INTELLIGENCE

How our brains give rise to our minds is one of the most intriguing questions in all of science. We are now living in a particularly interesting time to consider this question. This is true because, during the last decade, mathematical models about how the brain works have finally succeeded quantitatively simulating the experimentally recorded dynamics of individual cells in identified brain circuits and the behaviors that these circuits control. The models that have led to these successes incorporate qualitatively new ideas about how the brain is organized to achieve the remarkable flexibility and power of biological intelligence. These advances represent significant challenges and opportunities for mathematicians for several reasons. One obvious reason is that the models themselves are interesting mathematical objects. These models are typically defined by high-dimensional dynamical systems in which several types of nonlinear feedback operate across multiple spatial and temporal scales. They represent systems which are capable of autonomously adapting, or self-organizing, in response to a rapidly changing and unpredictable world. A second reason is that these models represent processes that are of great scientific and personal interest, including how we perceive a rapidly changing world, how we learn from it on our own, how we form expectations about what we believe will happen next, how we recognize complex events even if they occur in different contexts and from different viewpoints, how we join what we know about the world with what we feel about it to make decisions which are both possible and valued, how we selectively attend to events that particularly interest us, how we plan what to do next and carry out these plans despite the occurrence of multiple distracting events, and how we fuse together multiple types of information to decide where to look with our eyes, where to reach with our arms, and where to move with our legs. The great variety of these capabilities is mirrored by the heterogeneous organization of the brain into distinct but highly interacting parts, including such regions as the cerebral cortex, hippocampal system, cerebellum, basal ganglia, reticular formation, and so on. Detailed models of how these regions are organized have recently been proposed, notably how the characteristic organization of neocortex into layered circuits helps it to develop and learn in a stable way, to group distributed information into coherent representations without a loss of analog sensitivity, and to pay attention interesting events (Grossberg, 1999; Grossberg and Raizada, 2000).
Repositories for Software Reuse: The Software Information Base

Repositories play a pivotal role in an integrated reusebased application development environment. Reusing software components implies their persistent storage and maintenance, and the ability to efficiently find them. Repositories built with reuse in mind can be considered as special-purpose information systems, required to support powerful semantic modelling, flexible retrieval of varied software descriptions of multimedia nature, and efficiency optimization directed towards a large variety of classes rather than large populations per class. The Software Information Base (SIB), described in this paper, is an illustrative case where issues of organisation, multi-paradigm access and challenging implementation choices are set forth. Keyword Codes: D.2.2; D.2.9; H.3.3
Cross Sectional and Longitudinal Associations between Cardiovascular Risk Factors and Age Related Macular Degeneration in the EPIC-Norfolk Eye Study

PURPOSE
To examine the cross sectional and longitudinal relationship between cardiovascular risk factors and age-related macular degeneration (AMD) in a large British cohort study.


METHODS
The EPIC Norfolk Eye study is nested in a larger prospective cohort study. Data on cardiovascular risk factors were collected at baseline (1993-1997) and follow up (2006-2011) via clinical examination, validated lifestyle questionnaires and serum blood samples. AMD was ascertained using standardised grading of fundus photographs at the follow up. Logistic regression was used to examine associations between baseline and follow up risk factors with AMD.


RESULTS
5,344 pairs (62.0% of total 8623) of fundus photographs were of sufficient quality for grading of AMD in participants with mean age of 67.4 years old (range 44-91) at diagnosis. There were 28 cases of late AMD (0.5%, 95% confidence interval (CI)=0.3-0.8%) and 645 cases of early AMD (12.1%, 95%CI=11.2-13.0.%). In multivariable analysis, older people with higher levels of baseline high density lipoprotein- cholesterol (HDL-C ) and C-reactive protein (CRP) were more likely to have any signs of AMD, after adjusting for sex, education, smoking, and systolic blood pressure. In cross sectional analysis, only older age and higher HDL were significantly associated with AMD.


CONCLUSIONS
We have found that older age and higher levels of CRP and HDL-C were associated with increased odds of AMD in this population in the longitudinal analysis, but older age and HDL-C, not CRP was significantly associated with AMD in the cross sectional analysis. The prevalence of AMD in this cohort was low compared to other cohorts in Europe, the US and Australia, and probably reflects the some selection biases in follow up participation as well as the low rate of smoking among our healthy participants.
A cluster randomised trial to assess the impact of clinical pathways on AMI management in rural Australian emergency departments

BACKGROUND
People living in rural Australia are more likely to die in hospital following an acute myocardial infarction than those living in major cities. While several factors, including time taken to access hospital care, contribute to this risk, it is also partially attributable to the lower uptake of evidence-based guidelines for the administration of thrombolytic drugs in rural emergency departments where up to one-third of eligible patients do not receive this life-saving intervention. Clinical pathways have the potential to link evidence to practice by integrating guidelines into local systems, but their impact has been hampered by variable implementation strategies and sub-optimal research designs. The purpose of this study is to determine the impact of a five-step clinical pathways implementation process on the timely and efficient administration of thrombolytic drugs for acute myocardial infarctions managed in rural Australian emergency departments.


METHODS/DESIGN
The design is a two-arm, cluster-randomised trial with rural hospital emergency departments that treat and do not routinely transfer acute myocardial infarction patients. Six rural hospitals in the state of Victoria will participate, with three in the intervention group and three in the control group. Intervention hospitals will participate in a five-step clinical pathway implementation process: engagement of clinicians, pathway development according to local resources and systems, reminders, education, and audit and feedback. Hospitals in the control group will each receive a hard copy of Australian national guidelines for chest pain and acute myocardial infarction management. Each group will include 90 cases to give a power of 80% at 5% significance level for the two primary outcome measures: proportion of those eligible for thrombolysis receiving the drug and time to delivery of thrombolytic drug.


DISCUSSION
Improved compliance with thrombolytic guidelines via clinical pathways will increase acute myocardial infarction survival rates in rural hospitals and thereby help to reduce rural-urban mortality inequalities. Such knowledge translation has the potential to be adapted for a range of clinical problems in a wide array of settings.


TRIAL REGISTRATION
Australia New Zealand Clinical Trials Registry code ACTRN12608000209392.
Bounding Box Improvement With Reinforcement Learning

In this thesis, I explore a reinforcement learning technique for improving bounding box localizations of objects in images. The model takes as input a bounding box already known to overlap an object and aims to improve the fit of the box through a series of transformations that shift the location of the box by translation, or change its size or aspect ratio. Over the course of these actions, the model adapts to new information extracted from the image. This active localization approach contrasts with existing bounding-box regression methods, which extract information from the image only once. I implement, train, and test this reinforcement learning model using data taken from the Portland State Dog-Walking image set [12]. The model balances exploration with exploitation in training using an -greedy policy. I find that the performance of the model is sensitive to the -greedy configuration used during training, performing best when the epsilon parameter is set to very low values over the course of training. With = 0.01, I find the algorithm can improve bounding boxes in about 78% of test cases for the ‘dog’ object category, and 76% for the ‘human’ category.
Susceptibility of a potential animal model for pathological anxiety to chronic mild stress

When anxiety-related behaviour in animals appears to lack adaptive value, it might be defined as pathological. Adaptive behaviour can be assessed for example by changes in behavioural responses over time, i.e. habituation. Thus, non-adaptive anxiety would be reflected by a lack of habituation. Recently, we found that 129P3/J mice are characterised by non-adaptive avoidance behaviour after repeated test exposure. The present study was aimed at investigating the sensitivity of the behavioural profile of these animals to exposure to a chronic mild stress (CMS) paradigm followed by repeated exposure to the modified hole board test. If the behavioural profile of 129P3/J mice mirrors pathological anxiety, their behavioural habituation under repeated test exposure conditions should be affected by CMS treatment. The results confirm the profound lack of habituation with respect to anxiety-related behaviour in both control and CMS treated mice. Additionally, CMS treated animals revealed a lower exploratory behaviour, reduced locomotor activity and increased arousal-related behaviour over time when compared to control individuals, proving an extension of their impaired habituation behaviour. Although no effects of CMS treatment on plasma corticosterone levels were found, higher immediate early gene expression in the bed nucleus of the stria terminalis and the ventrolateral periaqueductal grey in CMS treated mice indicated that 129P3/J mice are susceptible to the negative effects of CMS treatment at both the behavioural and the functional level. These results support the hypothesis that 129P3/J mice might be an interesting model for pathological anxiety.
Cascaded Models for Articulated Pose Estimation

We address the problem of articulated human pose estimation by learning a coarse-to-fine cascade of pictorial structure models. While the fine-level state-space of poses of individual parts is too large to permit the use of rich appearance models, most possibilities can be ruled out by efficient structured models at a coarser scale. We propose to learn a sequence of structured models at different pose resolutions, where coarse models filter the pose space for the next level via their max-marginals. The cascade is trained to prune as much as possible while preserving true poses for the final level pictorial structure model. The final level uses much more expensive segmentation, contour and shape features in the model for the remaining filtered set of candidates. We evaluate our framework on the challenging Buffy and PASCAL human pose datasets, improving the state-of-the-art.
Sexual satisfaction in men with erectile dysfunction: correlates and potential predictors.

INTRODUCTION
Sexual satisfaction is an important treatment objective for men with erectile dysfunction (ED).


AIMS
To evaluate potential associations between International Index of Erectile Function (IIEF) satisfaction at study endpoint and a range of baseline, on-treatment, and endpoint variables.


METHODS
An exploratory analysis was conducted involving 3,935 subjects with ED randomized to on-demand tadalafil (N = 2,824) or placebo (N = 1,111) in randomized, controlled trials across 28 countries. Patients achieving scores > or =16 on IIEF questions 7, 8, 13, and 14 at study endpoint were operationally defined as satisfied (vs. <16, not satisfied). Multivariate logistic regression and other analyses were conducted to ascertain correlates and potential predictors of improvements in the IIEF-erectile function domain (IIEF-EF).


MAIN OUTCOME MEASURES
Satisfaction on the IIEF at study endpoint, on-treatment improvements in IIEF-EF, and endpoint sexual frequency.


RESULTS
Patients who were satisfied with sexual function were on average younger and had less severe ED, a shorter history of the condition, and no history of vascular disorders, hypertension, or diabetes mellitus/insulin use at baseline (P < 0.01 vs. not satisfied for each). Satisfied patients were also more likely to experience a > or =4-point increase on the IIEF-EF domain on treatment (adjusted odds ratio [OR] = 22.4; 95% CI = 17.6-28.5; P < 0.0001) or IIEF-EF > or =26 at endpoint (adjusted OR = 41.0; 95% CI = 33.6-50.2; P < 0.0001). Satisfaction emerged as a strong correlate of a > or =4-point increase in the IIEF-EF on treatment; however, as a correlate of endpoint sexual frequency, baseline sexual frequency was stronger than endpoint satisfaction.


CONCLUSIONS
Satisfaction is associated with certain baseline, on-treatment, and endpoint variables in ED patients. Further studies are needed to confirm these preliminary findings and explore their meaning for female partners.
Prospective randomized trial of high versus low negative pressure suction in management of chyle fistula after neck dissection for metastatic thyroid carcinoma.

BACKGROUND
Negative pressure drainage has been shown to be an effective treatment of chyle fistula. However, the optimal level of negative pressure has not been determined. We therefore conducted a prospective randomized trial to address this issue.


METHODS
In all, 21 patients with chyle fistula were randomly assigned to a high negative pressure suction (HNPS) group (-600 mmHg, n = 10) or low negative pressure suction (LNPS) group (-125 mmHg, n = 11). The duration of drain leakage and hospital stay, and the incidence of complications were compared between the 2 groups.


RESULTS
All patients were successfully treated with conservative management without surgical intervention. The median durations of chyle leakage and hospital stay were significantly shorter in the HNPS group compared with the LNPS group: 4 versus 7 days (p = .0048) and 5 versus 11 days (p = .0107), respectively.


CONCLUSIONS
Negative suction was demonstrated to be highly effective in the management of chyle fistula, and HNPS appeared to be more efficient than LNPS.
MEEM: Robust Tracking via Multiple Experts Using Entropy Minimization

1. Fig. 1 (Experiment I): the average precision plots and the success plots for the compared trackers (LSHT [2], LSST [3] and SPLTT [4]), which are not included in [1]. For the other 29 compared trackers, readers are referred to [1]. 2. Fig. 2 (Experiment I): the average precision plot ranking scores and the AUC ranking scores of the five leading trackers on different subsets of test sequences. 3. Fig. 3 and 4 (Experiment I): the precision plot ranking score tables and the AUC ranking score tables for the top five trackers. 4. Fig. 5 and 6 (Experiment I): the precision plot ranking score tables and the AUC ranking score tables for MEEM and its baselines. 5. Fig. 7 (Experiment II): the precision plot ranking score table and the AUC ranking score table for MEEM and the compared algorithms on our newly collected sequences.
Statistical affect detection in collaborative chat

Geographically distributed collaborative teams often rely on synchronous text-based online communication for accomplishing tasks and maintaining social contact. This technology leaves a trace that can help researchers understand affect expression and dynamics in distributed groups. Although manual labeling of affect in chat logs has shed light on complex group communication phenomena, scaling this process to larger data sets through automation is difficult. We present a pipeline of natural language processing and machine learning techniques that can be used to build automated classifiers of affect in chat logs. Interpreting affect as a dynamic, contextualized process, we explain our development and application of this method to four years of chat logs from a longitudinal study of a multi-cultural distributed scientific collaboration. With ground truth generated through manual labeling of affect over a subset of the chat logs, our approach can successfully identify many commonly occurring types of affect.
Barbed sutures: a review of the literature.

BACKGROUND
Despite substantial mention in the popular press, there is little in the plastic surgery or dermatology literature regarding the safety, efficacy, longevity, or complications of barbed suture suspension procedures. The authors review the literature to estimate several clinical parameters pertaining to barbed thread suspensions.


METHODS
The authors performed a MEDLINE search using the keywords "barbed and suture," "thread and suspension," "Aptos," "Featherlift," and "Contour Thread."


RESULTS
The authors identified six studies that met their criteria of addressing midface elevation with barbed thread suspension. These detected some adverse events, but most of these were minor, self-limited, and of short duration. Less clear are the data on the extent of the peak correction and the longevity of effect. Objective outcome measures and long-term follow-up data were not provided in a systematic manner in the few available studies.


CONCLUSIONS
Suspension of the aging face with barbed sutures offers the promise of a minimally invasive technique with diminished adverse events. The technique is in its infancy, but it has potential to be a useful and effective clinical tool as further innovations are made in the clinic and laboratory.