LLukas22/scidocs huggingface dataset:
Prevalence of symptoms of eczema in Latin America: results of the International Study of Asthma and Allergies in Childhood (ISAAC) Phase 3.

BACKGROUND
The aim of the International Study of Asthma and Allergies in Childhood (ISAAC) was to evaluate the prevalence of symptoms of eczema among children living in different parts of Latin America. Data were from centers that participated in ISAAC Phase 3.


METHODS
This was a cross-sectional questionnaire survey of 93,851 schoolchildren (6 to 7 years old) from 35 centers in 14 Latin American countries and 165,917 adolescents (13 to 14 years old) from 56 centers in 17 Latin American countries.


RESULTS
The mean prevalence of current flexural eczema in schoolchildren was 11.3%, ranging from 3.2% in Ciudad Victoria (Mexico) to 25.0% in Barranquilla (Colombia). For adolescents, the prevalence varied from 3.4% in Santo André (Brazil) to 30.2% in Barranquilla (mean prevalence, 10.6%). The mean prevalence of current symptoms of severe eczema among schoolchildren was 1.5%, ranging from 0.3% in Ciudad Victoria, Toluca, and Cuernavaca (Mexico) to 4.9% in La Habana (Cuba). For adolescents, the mean prevalence was 1.4%, ranging from 0.1% in Mexicali Valley (Mexico) to 4.2% in Santa Cruz (Bolivia). These prevalence values are among the highest observed during ISAAC Phase 3. In general, the prevalence of current symptoms of eczema was higher among the Spanish-speaking centers for both schoolchildren and adolescents.


CONCLUSION
Environmental risk factors must be evaluated in order to identify potential causes for the differences observed, even in centers from the same country.
Modelling and predictive control of an electro-hydraulic actuated wet clutch for automatic transmission

Multi-plate wet clutches and theirs actuators are an important part of the automatic transmission gearboxes. Modern electronic controls operate the clutch by an electro-hydraulic actuator. In this paper a new model for a wet clutch actuated by an electro-hydraulic valve used in a real vehicle for automatic transmission is developed. The model captures the essential dynamics of the electro-hydraulic valve and clutch circuit, which operates on a given pressure range commanded by a transmission shifting signal. The model is validated against the data obtained from a test bench which includes the DQ250 wet clutch actuated by the electro-hydraulic valve DQ500 and the comparison shows good agreement. Based on the developed model, a useful clutch prediction control scheme was designed. Simulation results obtained with predictive control strategy are presented and discussed.
Maya: Multiple-Dispatch Syntax Extension in Java

We have designed and implemented Maya, a version of Java that allows programmers to extend and reinterpret its syntax. Maya generalizes macro systems by treating grammar productions as generic functions, and semantic actions on productions as multimethods on the corresponding generic functions. Programmers can write new generic functions (i.e., grammar productions) and new multimethods (i.e., semantic actions), through which they can extend the grammar of the language and change the semantics of its syntactic constructs, respectively. Maya's multimethods are compile-time metaprograms that transform abstract syntax: they execute at program compile-time, because they are semantic actions executed by the parser. Maya's multimethods can be dispatched on the syntactic structure of the input, as well as the static, source-level types of expressions in the input. In this paper we describe what Maya can do and how it works. We describe how its novel parsing techniques work and how Maya can statically detect certain kinds of errors, such as code that generates references to free variables. Finally, to demonstrate Maya's expressiveness, we describe how Maya can be used to implement the MultiJava language, which was described by Clifton et al. at OOPSLA 2000.
Hybrid Client Side Phishing Websites Detection Approach

Phishing tricks to steal personal or credential information by entering victims into a forged website similar to the original site, and urging them to enter their information believing that this site is legitimate. The number of internet users who are becoming victims of phishing attacks is increasing beside that phishing attacks have become more sophisticated. In this paper we propose a client-side solution to protect against phishing attacks which is a Firefox extension integrated as a toolbar that is responsible for checking whether recipient website is trusted or not by inspecting URLs of each requested webpage. If the site is suspicious the toolbar is going to block it. Every URL is evaluated corresponding to features extracted from it. Three heuristics (primary domain, sub domain, and path) and Naïve Bayes classification using four lexical features combined with page ranking received from two different services (Alexa, and Google page rank) used to classify URL. The proposed method requires no server changes and will prevent internet users from fraudulent sites especially from phishing attacks based on deceptive URLs. Experimental results show that our approach can achieve 48% accuracy ratio using a test set of 246 URL, and 87.5% accuracy ratio by excluding NB addition tested over 162 URL. Keywords—Phishing Attacks; Browser Plugin; Anti Phishing; Security; Firefox
Predictors of positive growth after traumatic brain injury: a longitudinal study.

PRIMARY OBJECTIVE
To investigate long-term positive psychological growth in individuals with traumatic brain injury (TBI) and to relate growth to injury characteristics and early outcomes.


RESEARCH DESIGN
Longitudinal study.


METHOD AND PROCEDURE
Long-term follow-up of a group of TBI survivors recruited between 1991-1995. In 2004, 240 of the 563 original participants were invited to take part in a follow-up study. At follow-up, survivors completed the Positive Changes in Outlook Questionnaire (CiOP) along with a structured interview/questionnaire which permitted a Glasgow Outcome Scale (GOSE) score to be assigned.


RESULTS
One hundred and sixty-five TBI survivors completed both questionnaire and CiOP. One hundred and three (62%) participants had suffered severe TBI, 24 (15%) moderate and 38 (23%) mild. Mean length of follow-up was 11.5 years post-injury (range 9-25 years). On the GOSE at follow-up, 43 (26%) had severe disability; 72 (44%) moderate disability; and 50 (30%) good recovery. Scores on the CiOP indicated positive psychological growth in over half of the sample, as evidenced by agreement with items such as 'I don't take life for granted anymore' and 'I value my relationships much more now'. CiOP total scores did not correlate with any injury or early outcome variables. However, at long-term follow-up there was a negative correlation between positive growth and anxiety and depression.


CONCLUSION
Survivors of mild, moderate and severe TBI showed evidence of long-term positive changes in outlook.
Reflections on the Simulation of Complex Systems for Science

In studying complex systems, agent-based simulations offer the possibility of directly modelling components in an environment. However, the scientific value of agent-based simulations has been limited by inadequate scientific rigour. The paper focuses on agent-based simulations that are used in biological and bio-medical research. Starting from a review of best practice in simulation engineering, the paper identifies some of the key activities in developing complex systems simulations that support scientific research, and how these contribute to the essential development of mutual trust among developers and scientists. Examples from the authors' own experience illustrate how a range of studies have manifested these key activities, and identifies some successes and problems encountered.
[Differences in AIDS prevention among young men and women of public schools in Brazil].

OBJECTIVES
To investigate risk sexual for HIV infection among young adult night school students (18 to 25 years old) and to assess gender differences in sexual practices and the impact of AIDS prevention program.


METHODS
A longitudinal intervention study was carried out among students of four public inner-city night schools, in the city of São Paulo, Brazil, randomized into two groups: an intervention group and a control one. Three hundred and ninety-four students participated in the study; 77% completed the post-intervention questionnaire. The intervention consisted of a "Safer Sex Workshop" where the following topics were discussed: Aids symbolism, risk perception, influences of gender norms on attitudes, Aids-related knowledge, erotic and reproductive body, sexual pleasure, and condom use negotiation. Statistical analysis was performed using Pearson's Chi-square test and variance.


RESULTS
The frequency of condom use was low (33%). There were significant gender differences concerning sexuality and AIDS prevention. Workshop evaluation showed a statistically significant impact on women, who improved chiefly their attitudes regarding safer sex. Changes were not significant among men.


CONCLUSIONS
HIV risk infection can be lowered but more significant results can be achieved if gender differences and sexual scripts are taken into account while developing specific long-term community programs.
Patient choice of treatment for postpartum depression: a pilot study

Objective: The lack of systematic efficacy research makes the selection of optimal treatment for postpartum depression (PPD) difficult. Moreover, the treatment decisions for women with PPD who are breastfeeding are heavily influenced by their concerns about infant exposure to antidepressant medication. The objective of this pilot trial was to examine the clinical characteristics of women with PPD associated with treatment selection. Method: This open pilot trial offered 23 women with PPD one of 3 treatment options: sertraline, interpersonal psychotherapy (IPT), or their combination administered in an outpatient mental health setting over 12 weeks. Baseline and treatment outcome measures included the Hamilton Rating Scale for Depression (HRSD), the Beck Depression Inventory (BDI) and the Edinburgh Postnatal Depression Scale (EPDS). Results: Completers across all 3 treatment groups (n = 18) experienced significant clinical improvement with each of the 3 treatment modalities on the HRSD (p < 0.001), BDI (p < 0.001) and EPDS (p < 0.001). There were trends for women with a prior depression to more frequently choose sertraline as a treatment (alone or with IPT, p = 0.07), and for women who were breastfeeding to choose sertraline (alone or with IPT, p = 0.10) less frequently. Conclusion: In this small sample of women with PPD, most women chose IPT with or without sertraline. A larger randomized study could further confirm the suggested predictors of treatment selection identified in this study: previous depression and breastfeeding status.
Control of asthma triggers in indoor air with air cleaners: a modeling analysis

BACKGROUND
Reducing exposure to environmental agents indoors shown to increase asthma symptoms or lead to asthma exacerbations is an important component of a strategy to manage asthma for individuals. Numerous investigations have demonstrated that portable air cleaning devices can reduce concentrations of asthma triggers in indoor air; however, their benefits for breathing problems have not always been reproducible. The potential exposure benefits of whole house high efficiency in-duct air cleaners for sensitive subpopulations have yet to be evaluated.


METHODS
We used an indoor air quality modeling system (CONTAM) developed by NIST to examine peak and time-integrated concentrations of common asthma triggers present in indoor air over a year as a function of natural ventilation, portable air cleaners, and forced air ventilation equipped with conventional and high efficiency filtration systems. Emission rates for asthma triggers were based on experimental studies published in the scientific literature.


RESULTS
Forced air systems with high efficiency filtration were found to provide the best control of asthma triggers: 30-55% lower cat allergen levels, 90-99% lower risk of respiratory infection through the inhalation route of exposure, 90-98% lower environmental tobacco smoke (ETS) levels, and 50-75% lower fungal spore levels than the other ventilation/filtration systems considered. These results indicate that the use of high efficiency in-duct air cleaners provide an effective means of controlling allergen levels not only in a single room, like a portable air cleaner, but the whole house.


CONCLUSION
These findings are useful for evaluating potential benefits of high efficiency in-duct filtration systems for controlling exposure to asthma triggers indoors and for the design of trials of environmental interventions intended to evaluate their utility in practice.
The paradoxical psychological effects of lysergic acid diethylamide (LSD).

BACKGROUND
Lysergic acid diethylamide (LSD) is a potent serotonergic hallucinogen or psychedelic that modulates consciousness in a marked and novel way. This study sought to examine the acute and mid-term psychological effects of LSD in a controlled study.


METHOD
A total of 20 healthy volunteers participated in this within-subjects study. Participants received LSD (75 µg, intravenously) on one occasion and placebo (saline, intravenously) on another, in a balanced order, with at least 2 weeks separating sessions. Acute subjective effects were measured using the Altered States of Consciousness questionnaire and the Psychotomimetic States Inventory (PSI). A measure of optimism (the Revised Life Orientation Test), the Revised NEO Personality Inventory, and the Peter's Delusions Inventory were issued at baseline and 2 weeks after each session.


RESULTS
LSD produced robust psychological effects; including heightened mood but also high scores on the PSI, an index of psychosis-like symptoms. Increased optimism and trait openness were observed 2 weeks after LSD (and not placebo) and there were no changes in delusional thinking.


CONCLUSIONS
The present findings reinforce the view that psychedelics elicit psychosis-like symptoms acutely yet improve psychological wellbeing in the mid to long term. It is proposed that acute alterations in mood are secondary to a more fundamental modulation in the quality of cognition, and that increased cognitive flexibility subsequent to serotonin 2A receptor (5-HT2AR) stimulation promotes emotional lability during intoxication and leaves a residue of 'loosened cognition' in the mid to long term that is conducive to improved psychological wellbeing.
Critical success factors for implementing knowledge management in small and medium enterprises

Purpose – To date, critical success factors (CSFs) for implementing knowledge management (KM) in small and medium enterprises (SMEs) have not been systematically investigated. Existing studies have derived their CSFs from large companies’ perspectives and have not considered the needs of smaller businesses. This paper is aimed to bridge this gap. Design/methodology/approach – Existing studies on CSFs were reviewed and their limitations were identified. By integrating insights drawn from these studies as well as adding some new factors, the author proposed a set of 11 CSFs which is believed to be more suitable for SMEs. The importance of the proposed CSFs was theoretically discussed and justified. In addition, an empirical assessment was conducted to evaluate the extent of success of this proposition. Findings – The overall results from the empirical assessment were positive, thus reflecting the appropriateness of the proposed CSFs. Practical implications – The set of CSFs can act as a list of items for SMEs to address when adopting KM. This helps to ensure that the essential issues and factors are covered during implementation. For academics, it provides a common language for them to discuss and study the factors crucial for the success of KM in SMEs. Originality/value – This study is probably the first to provide an integrative perspective of CSFs for implementing KM in the SME sector. It gives valuable information, which hopefully will help this business sector to accomplish KM.
The therapeutic value of adolescents' blogging about social-emotional difficulties.

Research shows that writing a personal diary is a valuable therapeutic means for relieving emotional distress and promoting well-being, and that diary writing during adolescence helps in coping with developmental challenges. Current technologies and cultural trends make it possible and normative to publish personal diaries on the Internet through blogs--interactive, online forms of the traditional personal diary. We examined the therapeutic value of blogging for adolescents who experience social-emotional difficulties. The field experiment included randomly assigned adolescents, preassessed as having social-emotional difficulties, to 6 groups (26-28 participants in each): Four groups were assigned to blogging (writing about their difficulties or free writing; either open or closed to responses), a group assigned to writing a diary on personal computers, and a no-treatment control group. Participants in the 5 writing groups were instructed to post messages at least twice a week over 10 weeks. Outcome measures included scales of social-emotional difficulties and self-esteem, a social activities checklist, and textual analyses of participants' posts. Measurement took place at pre- and postintervention and at follow-up 2 months later. Results showed that participants maintaining a blog significantly improved on all measures. Participants writing about their difficulties in blogs open to responses gained the most. These results were consistent in the follow-up evaluation.
Assembly Technologies for Integrated Transmitter/Receiver Optical Sub-Assembly Modules

We have succeeded in developing three techniques, a precise lens-alignment technique, low-loss built-in Spatial Multiplexing optics and a well-matched electrical connection for high-frequency signals, which are indispensable for realizing compact high-performance TOSAs and ROSAs employing hybrid integration technology. The lens position was controlled to within ±0.3 μm by high-power laser irradiation. All components comprising the multiplexing optics are bonded to a prism, enabling the insertion loss to be held down to 0.8 dB due to the dimensional accuracy of the prism. The addition of an FPC layer reduced the impedance mismatch at the junction between the FPC and PCB. We demonstrated a compact integrated four-lane 25 Gb/s TOSA (15.1 mm × 6.5 mm × 5.6 mm) and ROSA (17.0 mm × 12.0 mm × 7.0 mm) using the built-in spatial Mux/Demux optics with good transmission performance for 100 Gb/s Ethernet. These are respectively suitable for the QSFP28 and CFP2 form factors. key words: hybrid integration, optical sub-assembly, 100 Gb/s Ethernet
Validation of three non-invasive markers in assessing the severity of liver fibrosis in chronic hepatitis C.

OBJECTIVE
To compare various biochemical markers i.e. APRI (AST to platelet ratio index), aspartate aminotransferase (AST) alanine aminotransferase (ALT) ratio, FIB-4 (AST, platelet, AST and age) with biopsy for assessing the severity of hepatic fibrosis in patients with hepatitis C.


STUDY DESIGN
Descriptive study.


PLACE AND DURATION OF STUDY
Medical Department, Liaquat University of Medical and Health Sciences, Jamshoro, from July 2005 to March 2007.


METHODOLOGY
Consecutive hepatitis C virus RNA positive and previously untreated patients were studied. Liver biopsy with histological evaluation and AST/ALT ratio, AST to platelet ratio index and FIB-4 were assessed in all patients. Receiver operative curves were developed.


RESULTS
There were 158 patients (109 males, 49 females). On histological grounds non-advanced fibrosis (F0-1) was present in 74 (46.5%) of cases, whereas 84 (53.5%) patients had advanced (F2-4) fibrosis. The area under the receiver operating characteristic curves of APRI < 0.05-1 and FIB-4 < 1.45 were 0.7 and 0.74 respectively, which means that APRI < 1 and FIB-4 < 1.45 will exclude advanced fibrosis in 70% and 74% of patients respectively. An APRI of > 1 and FIB-4 will predict advanced fibrosis in 87% and 98% of patients respectively. AST/ALT ratio was inferior to both of these biomarkers.


CONCLUSION
Both APRI and FIB-4 not only exclude minimal fibrosis but can predict advanced fibrosis in the majority of the patients. The simultaneous use of several indirect markers of liver fibrosis does not improve their diagnostic accuracy.
What's in a Name: A Study of Names, Gender Inference, and Gender Behavior in Facebook

In this paper, by crawling Facebook public profile pages of a l arge and diverse user population in New York City, we create a comp rehensive and contemporary first name list, in which each name is annotated with a popularity estimate and a gender probability. First, we use the name list as part of a novel and powerful tech nique for inferring Facebook users’ gender. Our name-centric approach to gende r prediction partitions the users into two groups, A andB, and is able to accurately predict genders for users belonging toA. Applying our methodology to NYC users in Facebook, we are able to achieve an accuracy of 95.2% for groupA consisting of95.1% of the NYC users. This is a significant improvement over recent r sults of gender prediction [14], which achieved a maximum accuracy of 77.2% based on users’ group affiliations. Second, having inferred the gender of most users in our Faceb ook dataset, we learn several interesting gender characteristics and anal yze how males and females behave in Facebook. We find, for example, that females a nd m les exhibit contrasting behaviors while hiding their attributes, such as gender, age, and sexual preference, and that females are more conscious about th eir online privacy on Facebook.
Goserelin for ovarian protection during breast-cancer adjuvant chemotherapy.

BACKGROUND
Ovarian failure is a common toxic effect of chemotherapy. Studies of the use of gonadotropin-releasing hormone (GnRH) agonists to protect ovarian function have shown mixed results and lack data on pregnancy outcomes.


METHODS
We randomly assigned 257 premenopausal women with operable hormone-receptor-negative breast cancer to receive standard chemotherapy with the GnRH agonist goserelin (goserelin group) or standard chemotherapy without goserelin (chemotherapy-alone group). The primary study end point was the rate of ovarian failure at 2 years, with ovarian failure defined as the absence of menses in the preceding 6 months and levels of follicle-stimulating hormone (FSH) in the postmenopausal range. Rates were compared with the use of conditional logistic regression. Secondary end points included pregnancy outcomes and disease-free and overall survival.


RESULTS
At baseline, 218 patients were eligible and could be evaluated. Among 135 with complete primary end-point data, the ovarian failure rate was 8% in the goserelin group and 22% in the chemotherapy-alone group (odds ratio, 0.30; 95% confidence interval [CI], 0.09 to 0.97; two-sided P=0.04). Owing to missing primary end-point data, sensitivity analyses were performed, and the results were consistent with the main findings. Missing data did not differ according to treatment group or according to the stratification factors of age and planned chemotherapy regimen. Among the 218 patients who could be evaluated, pregnancy occurred in more women in the goserelin group than in the chemotherapy-alone group (21% vs. 11%, P=0.03); women in the goserelin group also had improved disease-free survival (P=0.04) and overall survival (P=0.05).


CONCLUSIONS
Although missing data weaken interpretation of the findings, administration of goserelin with chemotherapy appeared to protect against ovarian failure, reducing the risk of early menopause and improving prospects for fertility. (Funded by the National Cancer Institute and others; POEMS/S0230 ClinicalTrials.gov number, NCT00068601.).