LLukas22/scidocs huggingface dataset:
Seller-Buyer Trust in Cross-Border E-Commerce: a Conceptual Model

We conceptualize and propose a theoretical model of sellers’ trust in buyers in the cross border ecommerce context. This model is based on by signalling theory, which is further refined by using trust theories and empirical findings from prior e-commerce trust research.
Childhood maltreatment increases risk for personality disorders during early adulthood.

BACKGROUND
Data from a community-based longitudinal study were used to investigate whether childhood abuse and neglect increases risk for personality disorders (PDs) during early adulthood.


METHODS
Psychosocial and psychiatric interviews were administered to a representative community sample of 639 youths and their mothers from 2 counties in the state of New York in 1975, 1983, 1985 to 1986, and 1991 to 1993. Evidence of childhood physical abuse, sexual abuse, and neglect was obtained from New York State records and from offspring self-reports in 1991 to 1993 when they were young adults. Offspring PDs were assessed in 1991 to 1993.


RESULTS
Persons with documented childhood abuse or neglect were more than 4 times as likely as those who were not abused or neglected to be diagnosed with PDs during early adulthood after age, parental education, and parental psychiatric disorders were controlled statistically. Childhood physical abuse, sexual abuse, and neglect were each associated with elevated PD symptom levels during early adulthood after other types of childhood maltreatment were controlled statistically. Of the 12 categories of DSM-IV PD symptoms, 10 were associated with childhood abuse or neglect. Different types of childhood maltreatment were associated with symptoms of specific PDs during early adulthood.


CONCLUSIONS
Persons in the community who have experienced childhood abuse or neglect are considerably more likely than those who were not abused or neglected to have PDs and elevated PD symptom levels during early adulthood. Childhood abuse and neglect may contribute to the onset of some PDs.
Risk of cancer in Turkish patients after treatment with TNF antagonists

MHC molecule expression and susceptibility to rheumatoid arthritis, multiple sclerosis and myocardial infarction. Nat Genet 2005;37:486–94. 4 Yazdani-Biuki B, Brickmann K, Wohlfahrt K et al. The MHC2TA -168A>G gene polymorphism is not associated with rheumatoid arthritis in Austrian patients. Arthritis Res Ther 2006;8:R97. 5 Orozco G, Robledo G, Linga Reddy MV et al. Study of the role of a functional polymorphism of MHC2TA in rheumatoid arthritis in three ethnically different populations. Rheumatology 2006;45:1442–4. 6 Eyre S, Bowes J, Spreckley K et al. Investigation of the MHC2TA gene, associated with rheumatoid Swedish population, in a UK rheumatoid arthritis cohort. Arthritis Rheum 2006;54:3417–22. 7 Iikuni N, Ikari K, Momohara S et al. MHC2TA is associated with rheumatoid arthritis in Japanese patients. Ann Rheum Dis 2007;66:274–5. 8 Okamoto H, Kaneko H, Terai C, Kamatani N. Protective effect of A at position -168 in the type III promoter of MHCIITA gene in Systemic Lupus Erythematosus (SLE). Ann Rheum Dis 2007;66:1263–4. 9 Okamoto H, Cujec TP, Okamoto M, Peterlin BM, Baba M, Okamoto T. Inhibition of the RNA-dependent transactivation and replication of human immunodeficiency virus type 1 by a fluoroquinoline derivative K-37. Virology 2000;272:402–8. 10 Martinez A, Sanchez-Lopez M, Varade J et al. Role of the MHC2TA gene in autoimmune diseases. Ann Rheum Dis 2007;66:325–9.
A ZRS duplication causes syndactyly type IV with tibial hypoplasia.

A ZRS Duplication Causes Syndactyly Type IV With Tibial Hypoplasia Lingqian Wu,* Desheng Liang, Norio Niikawa, Fen Ma, Miao Sun, Qian Pan, Zhigao Long, Zhongmin Zhou, Koh-ichiro Yoshiura, Hua Wang, Daisuke Sato, Gen Nishimura, Heping Dai, Xue Zhang, and Jiahui Xia National Laboratory of Medical Genetics, Central South University, Changsha, Hunan, China Solution Oriented Research of Science and Technology (SORST), Japan Science and Technology Agency (JST), Kawaguchi, Japan Research Institute of Personalized Health Sciences, Health Sciences University of Hokkaido, Hokkaido, Japan McKusick-Zhang Center for Genetic Medicine, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China Department of Human Genetics, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan Women and Children’s Hospital of Hunan Province, Changsha, Hunan, China Department of Radiology, Tokyo Metropolitan Kiyose Children’s Hospital, Tokyo, Japan
A Participatory Design in Developing Prototype an Augmented Reality Book for Deaf Students

One of Augmented Reality applications is known as Augmented Reality Book. Due to this, particular AR-Book is based on visually oriented technique and deaf students are generally classified as visual learners. The aim of this paper is to identify the criteria in developing an AR-Book for the deaf students. The AR-Book for deaf students is not the same as normal students because it has to include the sign language. In this ongoing study, qualitative approaches such as participatory design philosophy were used in designing and developing an AR-Book for deaf students. Three deaf students and three teachers who taught the deaf students were involved in this study. Two main findings showed that the sign language marker should be avoided and meanwhile, for the 3D model marker, it can work with the 2D picture or text. Therefore, it is more suitable to use sign language symbols in the AR-Book.
Predictors of new screening for African American men participating in a prostate cancer educational program

Background. African American (AA) men continue to have a greater than twofold risk of dying from prostate cancer compared to Whites. Methods. This community-based intervention study employed a quasi-experimental, delayed-control (cross-over) design with randomization at the church-level (N=345 AA men). Results. Logistic regression analyses revealed that the level of knowledge (b=.61, P<.05, Exp (B)=1.84), the perception of risk (b=2.99, P<.01, Exp (B)=19.95), and having insurance (b=3.20, P<.01, Exp (B)=24.65) significantly increased the odds of participants who needed screening getting screened during study. Discussion. This study demonstrated the need for education, community involvement, and increased access to encourage minority men to obtain needed health screenings.
Limited Durability of Viral Control following Treated Acute HIV Infection

BACKGROUND
Early treatment of acute HIV infection with highly active antiretroviral therapy, followed by supervised treatment interruption (STI), has been associated with at least transient control of viremia. However, the durability of such control remains unclear. Here we present longitudinal follow-up of a single-arm, open-label study assessing the impact of STI in the setting of acute HIV-1 infection.


METHODS AND FINDINGS
Fourteen patients were treated during acute HIV-1 infection and subsequently subjected to an STI protocol that required retreatment if viral load exceeded 50,000 RNA copies/ml plasma or remained above 5,000 copies/ml for more than three consecutive weeks. Eleven of 14 (79%) patients were able to achieve viral loads of less than 5,000 RNA copies/ml for at least 90 d following one, two, or three interruptions of treatment. However, a gradual increase in viremia and decline in CD4+ T cell counts was observed in most individuals. By an intention-to-treat analysis, eight (57%), six (43%), and three (21%) of 14 patients achieved a maximal period of control of 180, 360, and 720 d, respectively, despite augmentation of HIV-specific CD4+ and CD8+ T cell responses. The magnitude of HIV-1-specific cellular immune responses before treatment interruption did not predict duration of viremia control. The small sample size and lack of concurrent untreated controls preclude assessment of possible clinical benefit despite failure to control viremia by study criteria.


CONCLUSIONS
These data indicate that despite initial control of viremia, durable viral control to less than 5,000 RNA copies/ml plasma in patients following treated acute HIV-1 infection occurs infrequently. Determination of whether early treatment leads to overall clinical benefit will require a larger and randomized clinical trial. These data may be relevant to current efforts to develop an HIV-1 vaccine designed to retard disease progression rather than prevent infection since they indicate that durable maintenance of low-level viremia may be difficult to achieve.
Science-Policy Bridges Over Troubled Waters: Making Science Deliver Greater Impacts in Shared Water Systems

Enhancing the use of Science in International Waters projects to improve project results
Determination of the Number of Hydrogen-Bonds in a Protein Molecule

By means of an infrared-spectroscopic observation of the hydrogen-exchange reaction, the number of peptidepeptide hydrogen-bonds involved in a given protein molecule in its aqueous solution can be determined.
Mixture regression as subspace clustering

In this paper we show that observations in a mixture can be modeled using a union of subspaces, and hence mixture regression can be posed as a subspace clustering problem. This allows to perform mixture regression even in the presence of missing data. We illustrate this using a state-of-the-art subspace clustering algorithm for incomplete data to perform mixed linear regression on gene functional data. Our approach outperforms existing methods on this task.
Prevalence of fatigue in patients 3 months after stroke and association with early motor activity: a prospective study comparing stroke patients with a matched general population cohort

BACKGROUND
Fatigue is a common complaint after stroke. Reasons for higher prevalence are still unclear. This study aimed to determine if fatigue prevalence in stroke patients is different to that of age and gender matched general population controls, and to explore whether early motor activity was associated with reduced likelihood of fatigue three months after stroke.


METHODS
This was a prospective multicenter cohort study of stroke patients admitted to eleven regional Norwegian hospitals, within 14 days after stroke. Stroke patients (n = 257) were age and gender matched to participants in a general population health survey (HUNT3-survey) carried out in a regional county of central Norway. The single-item fatigue questionnaire from the HUNT3-survey was administered to both groups to compare prevalence. The association between early motor activity (time in bed, time sitting out of bed, and time upright) and fatigue at three months after stroke (Fatigue Severity Scale) was tested with logistic regression. Simple models including each activity outcome, with adjustment for stroke severity and pre-stroke function, were tested, as well as a comprehensive model that included additional independent variables of depression, pain, pre-stroke fatigue, age and gender.


RESULTS
Prevalence was higher after stroke compared with the general population: 31.1% versus 10.9%. In the simple regression models, none of the early motor activity categories were associated with fatigue three months after stroke. In the comprehensive model, depression, pain and pre-stroke fatigue were significantly associated with post-stroke fatigue. Time in bed through the daytime during hospital stay approached statistical significance (p = 0.058) with an odds ratio for experiencing fatigue of 1.02 (95% CI 1.00-1.04) for each additional 5.4 minutes in bed.


CONCLUSIONS
Stroke patients had higher prevalence of fatigue three months after stroke than the age and gender matched general population sample, which may be partly explained by the stroke population being in poorer health overall. The relationship between early motor activity (and inactivity) and fatigue remains unclear. Further research, which may help drive development of new treatments to target this challenging condition, is needed.
Prospective trial of intense pulsed light for the treatment of meibomian gland dysfunction.

PURPOSE
To evaluate the effect of intense pulsed light (IPL) applied to the periocular area for meibomian gland dysfunction (MGD) in a prospective, double-masked, placebo-controlled, paired-eye study.


METHODS
Twenty-eight participants underwent IPL treatment, with homogeneously sequenced light pulses delivered to one eye and placebo treatment to the partner control eye at 1, 15, and 45 days following baseline (BL) evaluation. Lipid layer grade (LLG), noninvasive tear break-up time (NIBUT), tear evaporation rate (TER), tear meniscus height (TMH), and subjective symptom score using visual analogue scales (VAS) were compared with BL and control values at each visit.


RESULTS
Lipid layer grade improved significantly from BL to Day (D) 45 in the treated eye (P < 0.001), but not the control eye (P = 0.714), with 82% of treated eyes improving by at least one LLG. Noninvasive tear break-up time also improved significantly from BL to D45 in the treated (P < 0.001) but not in the control eye (P = 0.056) and was significantly longer than in the treated eye at D45 (14.1 ± 9.8 seconds versus 8.6 ± 8.2 seconds, P < 0.001). The tear evaporation rate was not different in the treated eye compared with the control eye at any visit. Tear meniscus height did not change from BL in either eye (P > 0.05). Visual analog scale symptom scores improved from BL in the treated (P = 0.015), but not the control eye (P = 0.245), with 86% of participants noting reduced symptoms in the treated eye by D45.


CONCLUSIONS
Intense pulsed light with multiple sculpted pulses shows therapeutic potential for MGD, improving tear film quality and reducing symptoms of dry eye. ( https://www.anzctr.org.au number, ACTRN12614000162617.).
Whey proteins-Properties and Possibility of Application

Whey protein fractions represents 18-20% of total milk nitrogen content. β-lactoglobulin is the major milk serum protein, while α-lactalbumin represents about 20% of total serum proteins or 2-5% of total milk nitrogen content. Whey proteins are highly susceptible to heat-induced denaturation; irreversibly denature and coagulate when exposed to high temperatures. Thermal treatment causes interaction between milk proteins, especially the interaction of α-lactalbumin, β-lactoglobulin and κ-casein. Complexes between them are known as coaggregates. Since the early 1980s, whey proteins have grown in popularity as nutritional and functional food ingredients. Serum proteins possess favorable functional characteristics such as gelling, water binding, emulsification and foaming ability. Due to the use of membrane fractionation techniques, it is possible to produce various whey-protein based products. The most important products based on the whey proteins are whey protein concentrate (WPC), whey protein isolate (WPI) and hydrolyzed whey protein (HWP). This review discusses the properties of major whey protein components and their possible use in dairy industry.
Design and implementation of a LoRa based wireless control for drip irrigation systems

The deployment of drip irrigation systems has been prevailing over the last few decades and it poses many difficulties to manual control them once they are installed on a large scale. A common approach to overcome this issue is to set up a wireless sensor and actuator network (WSAN). However, using wireless technologies in the field of agriculture presents several technical challenges, such as achieving long battery life, long-range capabilities and low-cost at the same time. In recent years, many technologies and protocols have been deployed trying to overcome those challenges. One of them is LoRa, proprietary wireless modulation technology. The network protocol (LoRaWAN), which is built on top of Lora modulation, has been studied and analyzed as part of this paper. Considering the cost and the complexity of setting up LoRaWAN, this work proposes a simpler and cost-effective protocol designed specifically to control drip irrigation systems. The project that is described in this paper includes the implementation results of both hardware and software for the wireless nodes, and development of GUI app for controlling drip irrigation systems.
Bond Risk , Bond Return Volatility , and the Term Structure of Interest Rates

This paper explores time variation in bond risk, as measured by the covariation of bond returns with stock returns and with consumption growth, and in the volatility of bond returns. A robust stylized fact in empirical finance is that the spread between the yield on long-term bonds and short-term bonds forecasts positively future excess returns on bonds at varying horizons, and that the short-term nominal interest rate forecasts positively stock return volatility and exchange rate volatility. This paper presents evidence that movements in both the short-term nominal interest rate and the yield spread are positively related to changes in subsequent realized bond risk and bond return volatility. The yield spread appears to proxy for business conditions, while the short rate appears to proxy for inflation and economic uncertainty. A decomposition of bond betas into a real cash flow risk component, and a discount rate risk component shows that yield spreads have offsetting effects in each component. A widening yield spread is correlated with reduced cash-flow (or inflationary) risk for bonds, but it is also correlated with larger discount rate risk for bonds. The short rate forecasts only the discount rate component of bond beta. JEL classification: G12. 1Graduate School of Business Administration, Baker Libray 367, Harvard University, Boston MA 02163, USA, CEPR, and NBER. Email lviceira@hbs.edu. Website http://www.people.hbs.edu/lviceira/. I am grateful to John Campbell, Jakub Jurek, André Perold, participants in the Lisbon International Workshop on the Predictability of Financial Markets, and especially to two anonymous referees and Andréas Heinen for helpful comments and suggestions. I am also very grateful to Johnny Kang for exceptionally able research assistance. I acknowledge the Division of Research at the Harvard Business School for their generous financial support.
The role of ADAMTSs in arthritis

The ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family consists of 19 proteases. These enzymes are known to play important roles in development, angiogenesis and coagulation; dysregulation and mutation of these enzymes have been implicated in many disease processes, such as inflammation, cancer, arthritis and atherosclerosis. This review briefly summarizes the structural organization and functional roles of ADAMTSs in normal and pathological conditions, focusing on members that are known to be involved in the degradation of extracellular matrix and loss of cartilage in arthritis, including the aggrecanases (ADAMTS-4 and ADAMTS-5), ADAMTS-7 and ADAMTS-12, the latter two are associated with cartilage oligomeric matrix protein (COMP), a component of the cartilage extracellular matrix (ECM). We will discuss the expression pattern and the regulation of these metalloproteinases at multiple levels, including their interaction with substrates, induction by pro-inflammatory cytokines, protein processing, inhibition (e.g., TIMP-3, alpha-2-macroglobulin, GEP), and activation (e.g., syndecan-4, PACE-4).
Saline or albumin for fluid resuscitation in patients with traumatic brain injury.

BACKGROUND
The Saline versus Albumin Fluid Evaluation study suggested that patients with traumatic brain injury resuscitated with albumin had a higher mortality rate than those resuscitated with saline. We conducted a post hoc follow-up study of patients with traumatic brain injury who were enrolled in the study.


METHODS
For patients with traumatic brain injury (i.e., a history of trauma, evidence of head trauma on a computed tomographic [CT] scan, and a score of < or =13 on the Glasgow Coma Scale [GCS]), we recorded baseline characteristics from case-report forms, clinical records, and CT scans and determined vital status and functional neurologic outcomes 24 months after randomization.


RESULTS
We followed 460 patients, of whom 231 (50.2%) received albumin and 229 (49.8%) received saline. The subgroup of patients with GCS scores of 3 to 8 were classified as having severe brain injury (160 [69.3%] in the albumin group and 158 [69.0%] in the saline group). Demographic characteristics and indexes of severity of brain injury were similar at baseline. At 24 months, 71 of 214 patients in the albumin group (33.2%) had died, as compared with 42 of 206 in the saline group (20.4%) (relative risk, 1.63; 95% confidence interval [CI], 1.17 to 2.26; P=0.003). Among patients with severe brain injury, 61 of 146 patients in the albumin group (41.8%) died, as compared with 32 of 144 in the saline group (22.2%) (relative risk, 1.88; 95% CI, 1.31 to 2.70; P<0.001); among patients with GCS scores of 9 to 12, death occurred in 8 of 50 patients in the albumin group (16.0%) and 8 of 37 in the saline group (21.6%) (relative risk, 0.74; 95% CI, 0.31 to 1.79; P=0.50).


CONCLUSIONS
In this post hoc study of critically ill patients with traumatic brain injury, fluid resuscitation with albumin was associated with higher mortality rates than was resuscitation with saline. (Current Controlled Trials number, ISRCTN76588266 [controlled-trials.com].).
Psoriatic arthritis and nail changes: exploring the relationship.

OBJECTIVE
Psoriatic arthritis (PsA) has a diverse range of clinical manifestations, both articular and extra-articular. Although the association of PsA with skin changes is well established, the relationship of PsA with psoriatic nail changes remains relatively unexplored.


METHODS
This report reviews the current literature surrounding the association of PsA with nail changes. A review of the literature was completed using PubMed, MEDLINE, and EMBASE in September 2013, encompassing years 1964-2012.


RESULTS
A total of 21 articles were reviewed. On average, 66% [standard deviation (SD) 17.7] of PsA patients had nail changes. The type of nail changes and their associations varied widely between studies.


CONCLUSIONS
Studies of nail changes in PsA are highly variable with a wide range of results. Given the variability of results that were observed in this review, our recommendations are that further large studies on nail changes in patients with PsA should be conducted.
Correlates of reduced exercise behaviour in depression: the role of motivational and volitional deficits.

OBJECTIVE
The study aimed at uncovering the correlates of reduced exercise in depressive patients. On the basis of the Health Action Process Approach (Schwarzer, 2011 ), we hypothesised that reduced exercise in depressive patients can be explained by motivational deficits and volitional deficits.


DESIGN
A longitudinal sample of 56 clinically depressive outpatients was compared to a sample of 56 parallelised non-depressive controls.


MAIN OUTCOME MEASURES
Self-reported intention, exercise, and motivational and volitional HAPA variables were measured with self-report questionnaires at baseline and four-week follow-up.


RESULTS
Depressive patients showed a motivational deficit: they had significantly reduced intentions to exercise compared to non-depressive participants, and they suffered from reduced self-efficacy and increased negative outcome expectations. No differences were found with regard to positive outcome expectations. Depressive patients also showed a volitional deficit: depressive high-intenders were less capable of transforming their intention into action than non-depressive high-intenders. They produced less action plans, had less maintenance self-efficacy and were more easily distracted by barriers.


CONCLUSION
The lower level of exercise among depressive patients is partly due to motivational, partly to volitional deficits. Interventions should be stage-matched and should focus on pessimistic beliefs (negative outcome expectations, self-efficacy) and planning deficits in depression.