LLukas22/scidocs huggingface dataset:
Framework for Analyzing Android I/O Stack Behavior: From Generating theWorkload to Analyzing the Trace

The existing I/O workload generators and trace capturing tools are not adaptable to generating nor capturing the I/O requests of Android apps. The Android platform needs proper tools to capture and replay real world workload in the Android platform to verify the result of benchmark tools. This paper introduces Android Storage Performance Analysis Tool, AndroStep, which is specifically designed for characterizing and analyzing the behavior of the I/O subsystem in Android based devices. The AndroStep consists of Mobibench (workload generator), MOST (Mobile Storage Analyzer), and Mobigen (workload replayer). Mobibench is an Android app that generates a filesystem as well as SQLite database operations. Mobibench can also vary the number of concurrent threads to examining the filesystem scalability to support concurrency, e.g., metadata updates, journal file creation/deletion. MOST captures the trace and extracts key filesystem access characteristics such as access pattern with respect to file types, ratio between random vs. sequential access, ratio between buffered vs. synchronous I/O, fraction of metadata accesses, etc. MOST implements reverse mapping feature (finding an inode for a given block) and retrospective reverse mapping (finding an inode for a deleted file). Mobigen is a trace capturing and replaying tool that is specifically designed to perform the user experiment without actual human intervention. Mobigen records the system calls generated from the user behavior and sanitizes the trace for replayable form. Mobigen can replay this trace on different Android platforms or with different I/O stack configurations. As an ∗Primitive version of this paper has been presented at the 1st European Workshop on Mobile Engineering (ME13) [1]. Future Internet 2013, 5 592 example of using AndroStep, we analyzed the performances of twelve Android smartphones and the SQLite performances on five different filesystems. AndroStep makes otherwise time consuming I/O stack analysis extremely versatile. AndroStep makes a significant contribution in terms of shedding light on internal behavior of the Android I/O stack.
Design and development of a safe robot manipulator using a new actuation concept

This paper presents the design and development of a novel two Degrees-Of-Freedom (DOF) safe robot manipulator. Magneto-Rheological (MR) clutches are incorporated in the design to enable antagonistic actuation at the joints. A single unidirectional motor supports bidirectional actuation of all joints. Unlike most current safe robots, high quality actuation is preserved, while the manipulator weight and effective inertia are reduced. This is achieved by relocating the driving motor to the base of the robot. Moreover, MR clutches have been shown to pose superior torque to mass, and torque to inertia characteristics over conventional servo motors, further contributing to the reduction of manipulator mass and inertia. The manipulator exhibits both high performance and intrinsic safety as a result of mechanically passive dynamics. A set of experiments is performed to validate the manipulator performance.
Knowledge sharing behaviour and its predictors

Purpose – This paper aims to evaluate the influence of different factors on knowledge donation and collection. The examined factors are among those determinants which comprise different aspects of knowledge sharing behaviour in an organisational context. Design/methodology/approach – Based on the widely accepted theory of planned behaviour (TPB), we tried to develop a comprehensive model. The model covered different individual and organisational factors. Responses to a total of 502 questionnaires were considered. Structural equation modelling was then used to test the research model and hypotheses. Findings – This research evaluated the influence of a series of potential factors on knowledge sharing behaviour. While perceived self-efficacy and anticipated reciprocal relationships had a positive impact on attitude toward knowledge sharing, expected extrinsic rewards did not show a significant relationship with this variable. Organisational climate had a positive impact on subjective norms about knowledge sharing. In addition, the level of information and communication technology usage reflected a positive effect on knowledge sharing behaviour. Finally, significant relationships were found between the TPB elements. Originality/value – This paper has tried to provide a comprehensive understanding about knowledge sharing facilitators in the oil industry. Since there was a lack of such research in an Iranian context, this paper can provide theoretical basis for future researches as well as practical implications for managers and practitioners.
Comprehending emotional eating in obese youngsters: the role of parental rejection and emotion regulation

Objectives:The present study examined the role of emotion regulation in the relation between parental rejection and emotional eating of obese youngsters.Method:Participants were 110 obese youngsters between the ages of 10 and 16 years who were referred to a Belgian treatment centre for obesity. Participants completed questionnaires assessing maternal and paternal rejection, emotion regulation strategies and emotional eating during their intake at the treatment centre. Bootstrapping procedure was used to test if emotion regulation mediated the relationship between maternal and paternal rejection on the one hand and emotional eating of the youngster on the other hand.Results:Results revealed that the use of maladaptive emotion regulation strategies mediated the relation between maternal rejection and emotional eating. Paternal rejection was neither associated with the emotion regulation nor with the emotional eating of the youngster.Discussion:The findings highlight the importance of assessing the emotional bond between mother and child and the emotion regulation of the youngster in the treatment of pediatric obesity.
Effect of intra-articular corticosteroid injections and inflammation on periarticular and generalised bone loss in early rheumatoid arthritis.

OBJECTIVES
To explore the effect of intra-articular corticosteroid (IAST) injections on bone mineral density (BMD) in the hand and at the metacarpophalangeal (MCP) joints in early rheumatoid arthritis (RA).


METHODS
In the first 3 months of the study, 19 patients with RA received methotrexate (MTX) alone and 21 received MTX and IAST injections into clinically inflamed joints. In the following 9 months, all patients received MTX+IAST. BMD was assessed at the hand and periarticular regions at MCP joints 2-5 at baseline, 3 and 12 months.


RESULTS
In the first 3 months a numerically lower percentage rate of bone loss was seen in MTX+IAST-treated patients compared with MTX-treated patients. This observation was more pronounced at the MCP periarticular regions (eg, partial proximal phalanges: digit 2, -0.45% vs -2.69%, p=0.045; digit 3, -0.34% vs -3.32%, p=0.003; digit 4, -0.39% vs -2.57%, p=0.14; digit 5, -0.59% vs -2.70%, p=0.24) than for the whole hand (-1.53% vs -2.42%, p=0.32). In the 3-12-month period, only minor non-statistically significant differences were seen between the two groups.


CONCLUSION
IAST given over 3 months protects against periarticular bone loss in inflamed finger joints in RA. These data emphasise the importance of suppressing inflammation in patients with active RA to maintain bone health.
Fuzzy J-Means and VNS methods for clustering genes from microarray data

MOTIVATION
In the interpretation of gene expression data from a group of microarray experiments that include samples from either different patients or conditions, special consideration must be given to the pleiotropic and epistatic roles of genes, as observed in the variation of gene coexpression patterns. Crisp clustering methods assign each gene to one cluster, thereby omitting information about the multiple roles of genes.


RESULTS
Here, we present the application of a local search heuristic, Fuzzy J-Means, embedded into the variable neighborhood search metaheuristic for the clustering of microarray gene expression data. We show that for all the datasets studied this algorithm outperforms the standard Fuzzy C-Means heuristic. Different methods for the utilization of cluster membership information in determining gene coregulation are presented. The clustering and data analyses were performed on simulated datasets as well as experimental cDNA microarray data for breast cancer and human blood from the Stanford Microarray Database.


AVAILABILITY
The source code of the clustering software (C programming language) is freely available from Nabil.Belacel@nrc-cnrc.gc.ca
Cardiac rehabilitation outcomes in women with chronic heart failure: mood, fitness, and exercise safety.

INTRODUCTION
Chronic heart failure (CHF) is a leading cause of morbidity in the industrialized world; both men and women are affected in significant numbers. However, women are underrepresented in heart failure literature, and there is limited evidence of their cardiac rehabilitation outcomes. The purpose of this study was to examine the efficacy of a cardiac rehabilitation program in female CHF patients.


METHODS
In a prospective cohort study, 60 female CHF subjects (median age, 59 years; median ejection fraction, 30%) were compared with 172 male CHF subjects (median age, 60 years; median ejection fraction, 27%), who completed an outpatient cardiac rehabilitation program. Self-reported exercise levels and intensity, fitness (6-minute walk test [6MWT]), and depressed mood (Cardiac Depression Scale) were recorded and compared at admission and discharge. Questionnaires were also re-administered at patient review conducted 3 months postdischarge.


RESULTS
Both female and male subjects made significant improvements in exercise levels (P < .05), exercise intensity (P < .001), fitness (P < .001), and mood (P < .001) during rehabilitation. Women showed significantly greater improvement in 6MWT results by discharge (P = .007) compared with men. At discharge, fewer women than men (78% vs 88%) reported exercising to adequate levels (≥ 150 minutes/week), but this had reversed at 3 months postdischarge.


CONCLUSIONS
Women with heart failure demonstrate similar patterns of improvement during cardiac rehabilitation compared with men and, in fact, show greater improvements in fitness and longer term exercise levels. Low to moderate intensity cardiac rehabilitation is both safe and effective in this group.
Big Data Analysis: Apache Storm Perspective

the boom in the technology has resulted in emergence of new concepts and challenges. Big data is one of those spoke about terms today. Big data is becoming a synonym for competitive advantages in business rivalries. Despite enormous benefits, big data accompanies some serious challenges and when it comes to analyzing of big data, it requires some serious thought. This study explores Big Data terminology and its analysis concepts using sample from Twitter data with the help of one of the most industry trusted real time processing and fault tolerant tool called Apache Storm. Keywords— Big Data, Apache Storm, real-time processing, open Source.
Feasibility of minocycline and doxycycline use as potential vasculostatic therapy for brain vascular malformations: pilot study of adverse events and tolerance.

BACKGROUND
Tetracyclines may be useful in preventing pathological vascular remodeling, thus decreasing the risk of spontaneous hemorrhage from brain vascular malformations.


METHODS
Arteriovenous malformation (AVM) and intracranial aneurysm patients undergoing noninvasive management were treated with minocycline or doxycycline (200 mg/day) up to 2 years in a prospective open-label safety pilot trial. The primary outcome was to compare dose-limiting intolerance, defined as treatment-related dose reduction or withdrawal between the agents.


RESULTS
Twenty-six patients with AVMs (n = 12) or aneurysms (n = 14) were recruited. Adverse event rates were similar to other reported trials of these agents; 4 of 13 (31%) minocycline and 3 of 13 (23%) doxycycline patients had dose-limiting intolerance (hazard ratio = 3.1, 95% CI = 0.52-18.11, log rank p = 0.70).


CONCLUSIONS
It is feasible to propose a long-term trial to assess the potential benefit of tetracycline therapy to decrease hemorrhagic risk in brain vascular malformations.
Immediate medical care after sexual assault.

Immediate needs after sexual assault include safety and privacy in the first instance, followed by treatment of injuries and prevention of unwanted pregnancy and sexually transmitted infections, including human immunodeficiency virus. Management should include risk identification of self-harm and suicide, as well as safeguarding children and vulnerable adults. Pregnancy prevention can be achieved through oral or mechanical methods of emergency contraception. Availability of emergency contraception may vary between districts and countries, depending on local laws and cultural or religious beliefs. Sexually transmitted infections, including gonorrhoea, chlamydia, hepatitis B and human immunodeficiency virus, represent an important part of management of victims of sexual assault. They can be prevented immediately by offering bacterial and viral prophylaxis followed by sexual health screening 2 weeks later unless symptomatic. In deciding what antibiotics to use as prophylaxis, local prevalence of infections and resistance to antibiotics should be considered. Prophylaxis against human immunodeficiency virus infection after sexual exposure should be discussed and offered in high-risk cases for up to 72 h after exposure. This should be accompanied by baseline human immunodeficiency virus test and referral for follow up. In high prevalence areas, prophylaxis against human immunodeficiency virus infection after sexual exposure should be offered as a routine. Psychosocial support and risk assessment of vulnerabilities, including self-harm or domestic violence and practical support should be addressed and acted on depending on identified needs.
A phase 2 clinical trial of deforolimus (AP23573, MK-8669), a novel mammalian target of rapamycin inhibitor, in patients with relapsed or refractory hematologic malignancies.

PURPOSE
Deforolimus (AP23573), a novel non-prodrug rapamycin analogue, inhibits the mammalian target of rapamycin, a downstream effector of the phosphatidylinositol 3-kinase/Akt and nutrient-sensing pathways. A phase 2 trial was conducted to determine the efficacy and safety of single-agent deforolimus in patients with relapsed or refractory hematologic malignancies.


EXPERIMENTAL DESIGN
Eligible patients were assigned to one of five disease-specific, parallel cohorts and given 12.5 mg deforolimus as a 30-minute infusion once daily for 5 days every 2 weeks. A Simon two-stage design was used for each cohort. Safety, pharmacokinetics, pharmacodynamics, and antitumor response were assessed.


RESULTS
Fifty-five patients received deforolimus as follows: cohort 1 23 acute myelogenous leukemia, two myelodysplastic syndrome and one chronic myelogenous leukemia in nonlymphoid blast phase; cohort 2, one acute lymphocytic leukemia; cohort 3, nine agnogenic myeloid metaplasia; cohort 4, eight chronic lymphocytic leukemia; cohort 5, nine mantle cell lymphoma and two T-cell leukemia/lymphoma. Most patients were heavily pretreated. Of the 52 evaluable patients, partial responses were noted in five (10%), two of seven agnogenic myeloid metaplasia and three of nine mantle cell lymphoma. Hematologic improvement/stable disease was observed in 21 (40%). Common treatment-related adverse events, which were generally mild and reversible, were mouth sores, fatigue, nausea, and thrombocytopenia. Decreased levels of phosphorylated 4E-BP1 in 9 of 11 acute myelogenous leukemia/myelodysplastic syndrome patients after therapy showed mammalian target of rapamycin inhibition by deforolimus.


CONCLUSIONS
Deforolimus was well-tolerated in patients with heavily pretreated hematologic malignancies, and antitumor activity was observed. Further investigation of deforolimus alone and in combination with other therapeutic agents is warranted in patients with selected hematologic malignancies.
Naval combat survivability testbeds for investigation of issues in shipboard power electronics based power and propulsion systems

There are numerous issues involved in the design of power electronics based power distribution and propulsion systems. These issues include power density, dynamic stability, efficiency, acoustic and waterborne noise, and electromagnetic compatibility, to name a few. In order to address these issues, as well as to test CAD tools for designing these systems, two reduced scale hardware test beds have been developed. The first of these, the Naval Combat Survivability Generation and Propulsion Testbed, focuses on primary power generation and propulsion. The second of these, the Naval Combat Survivability DC Distribution test bed, focuses on DC power distribution using a zonal architecture.
Allozyme diversity in the federally threatened golden paintbrush, Castilleja levisecta (Scrophulariaceae)

Castilleja levisecta (Scrophulariaceae), the golden paintbrush, is an insect-pollinated herbaceaous perennial found in the Pacific Northwest. Currently restricted to two island populations off British Columbia and nine populations (eight on islands) in Washington, C. levisecta is a rare species threatened with extinction. Allozymes were used to describe genetic diversity and structure in these eleven populations. Despite its threatened status and small geographic range, exceptionally high levels of genetic diversity are maintained within C. levisecta. All sixteen of the loci resolved were polymorphic within the species (Ps=100%), while the mean percentage of loci polymorphic within populations (Pp) was 65.7%. The mean number of alleles per polymorphic locus (APs) was 2.94 within the species and averaged 2.38 within populations (APp). Genetic diversity (Hes) was 0.285 for the species, whereas mean population genetic diversity (Hep) was 0.213. Smaller populations had, on average, fewer observed alleles and less genetic diversity. A significant negative correlation (r = −0.72) was found between genetic identity and geographic distance, indicating reduced gene flow between distant populations. The most geographically isolated population was one of the larger populations, one of the most genetically diverse and the most genetically divergent. A wide range of pairwise population genetic identities (I = 0.771 − 0.992) was found, indicating considerable genetic divergence between some populations. Overall, 19% of the total genetic diversity was distributed among populations. Results of this survey indicate that genetic augmentation of existing populations is unnecessary. The high allelic diversity found for the species and within its populations holds promise for conservation and restoration efforts to save this rare and threatened plant species.
Obstacle Avoidance for Spatial Hyper-Redundant Manipulators Using Harmonic Potential Functions and the Mode Shape Technique

This paper deals with the obstacle avoidance problem for spatial hyper-redundant manipulators in known environments. The manipulator is divided into two sections, a proximal section that has not entered the space among the obstacles and a distal section among the obstacles. Harmonic potential functions are employed to achieve obstacle avoidance for the distal section in three-dimensional space in order to avoid local minima in cluttered environments. A modified panel method is used to generate the potential of any arbitrary shaped obstacle in three-dimensional space. An alternative backbone curve concept and an efficient fitting method are introduced to control the trajectory of proximal links. The fitting method is recursive and avoids the complications involved with solving large systems of nonlinear algebraic equations. The combination of a three-dimensional safe path derived from the harmonic potential field and the backbone curve concept leads to an elegant kinematic control strategy that guarantees obstacle avoidance. © 2003 Wiley Periodicals, Inc.
Escaping the Great Recession

While high uncertainty is an inherent implication of the economy entering the zero lower bound, deflation is not, because agents are likely to be uncertain about the way policymakers will deal with the large stock of debt arising from a severe recession. We draw this conclusion based on a new-Keynesian model in which the monetary/fiscal policy mix can change over time and zero-lower-bound episodes are recurrent. Given that policymakers’behavior is constrained at the zero lower bound, beliefs about the exit strategy play a key role. Announcing a period of austerity is detrimental in the short run, but it preserves macroeconomic stability in the long run. A large recession can be avoided by abandoning fiscal discipline, but this results in a sharp increase in macroeconomic instability once the economy is out of the recession. Contradictory announcements by the fiscal and monetary authorities can lead to high inflation and large output losses. The policy trade-off can be resolved by committing to inflate away only the portion of debt resulting from an unusually large recession. ∗We are grateful to Gadi Barlevy, Dario Caldara, Jeff Campbell, Gauti Eggertsson, Marty Eichenbaum, Martin Ellison, Jesus Fernandez-Villaverde, Jonas Fisher, Alejandro Justiniano, Christian Matthes, Maurice Obstfeld, Giorgio Primiceri, Ricardo Reis, David Romer, Chris Sims, Martin Uribe, Mike Woodford, as well as all seminar participants at the NBER Summer Institute, SITE-Stanford University, Northwestern University, NY Fed, Chicago Fed, SED Annual Meeting, Cornell University, University of Wisconsin-Madison, Cleveland Fed, UPF, ECB, ESSIM Tarragona, Goethe University, Bonn University, Bank of England, UC Irvine, and the University of British Columbia for useful comments and suggestions. The views in this paper are solely the responsibility of the authors and should not be interpreted as reflecting the views of the Federal Reserve Bank of Chicago or any other person associated with the Federal Reserve System. Correspondence: Francesco Bianchi, francesco.bianchi@duke.edu, Leonardo Melosi, lmelosi@frbchi.org.
Cardiac Propagation Pattern Mapping With Vector Field for Helping Tachyarrhythmias Diagnosis With Clinical Tridimensional Electro-Anatomical Mapping Tools

Ventricular (VT) and atrial (AT) tachycardias are some of the most common clinical cardiac arrhythmias. For ablation of tachycardia substrates, two clinical diagnosis methods are used: invasive electroanatomical mapping for an accurate diagnosis using electrograms (EGMs) acquired with intracardiac catheters, and localized on the surface mesh of the studied cavities; and noninvasive electrocardiographic imaging (ECGi) for a global view of the arrhythmia, with EGMs mathematically reconstructed from body surface electrocardiograms using 3-D cardio-thoracic surface meshes obtained from CT-scans. In clinics, VT and AT are diagnosed by studying activation time maps that depict the propagation of the activation wavefront on the cardiac mesh. Nevertheless, slow conduction areas—a well-known proarrhythmic feature for tachycardias—and tachycardia specific propagation patterns are not easily identifiable with these maps. Therefore, local characterization of the activation wavefront propagation can be helpful for improving VT and AT diagnoses. The purpose of this study is to develop a method to locally characterize the activation wavefront propagation for clinical data. For this, a conduction velocity vector field is estimated and analyzed using divergence and curl mathematical operators. The workflow was first validated on a simulated database from computer models, and then applied to a clinical database obtained from ECGi to improve AT diagnosis. The results show the relevancy and the efficacy of the proposed method to guide ablation of tachyarrhythmias.