LLukas22/scidocs huggingface dataset:
Children balance theories and evidence in exploration, explanation, and learning

We look at the effect of evidence and prior beliefs on exploration, explanation and learning. In Experiment 1, we tested children both with and without differential prior beliefs about balance relationships (Center Theorists, mean: 82 months; Mass Theorists, mean: 89 months; No Theory children, mean: 62 months). Center and Mass Theory children who observed identical evidence explored the block differently depending on their beliefs. When the block was balanced at its geometric center (belief-violating to a Mass Theorist, but belief-consistent to a Center Theorist), Mass Theory children explored the block more, and Center Theory children showed the standard novelty preference; when the block was balanced at the center of mass, the pattern of results reversed. The No Theory children showed a novelty preference regardless of evidence. In Experiments 2 and 3, we follow-up on these findings, showing that both Mass and Center Theorists selectively and differentially appeal to auxiliary variables (e.g., a magnet) to explain evidence only when their beliefs are violated. We also show that children use the data to revise their predictions in the absence of the explanatory auxiliary variable but not in its presence. Taken together, these results suggest that children's learning is at once conservative and flexible; children integrate evidence, prior beliefs, and competing causal hypotheses in their exploration, explanation, and learning.
Ecological factors associated with dengue fever in a central highlands Province, Vietnam

BACKGROUND
Dengue is a leading cause of severe illness and hospitalization in Vietnam. This study sought to elucidate the linkage between climate factors, mosquito indices and dengue incidence.


METHODS
Monthly data on dengue cases and mosquito larval indices were ascertained between 2004 and 2008 in the Dak Lak province (Vietnam). Temperature, sunshine, rainfall and humidity were also recorded as monthly averages. The association between these ecological factors and dengue was assessed by the Poisson regression model with adjustment for seasonality.


RESULTS
During the study period, 3,502 cases of dengue fever were reported. Approximately 72% of cases were reported from July to October. After adjusting for seasonality, the incidence of dengue fever was significantly associated with the following factors: higher household index (risk ratio [RR]: 1.66; 95% confidence interval [CI]: 1.62-1.70 per 5% increase), higher container index (RR: 1.78; 95% CI: 1.73-1.83 per 5% increase), and higher Breteau index (RR: 1.57; 95% CI: 1.53-1.60 per 5 unit increase). The risk of dengue was also associated with elevated temperature (RR: 1.39; 95% CI: 1.25-1.55 per 2 °C increase), higher humidity (RR: 1.59; 95% CI: 1.51-1.67 per 5% increase), and higher rainfall (RR: 1.13; 95% CI: 1.21-1.74 per 50 mm increase). The risk of dengue was inversely associated with duration of sunshine, the number of dengue cases being lower as the sunshine increases (RR: 0.76; 95% CI: 0.73-0.79 per 50 hours increase).


CONCLUSIONS
These data suggest that indices of mosquito and climate factors are main determinants of dengue fever in Vietnam. This finding suggests that the global climate change will likely increase the burden of dengue fever infection in Vietnam, and that intensified surveillance and control of mosquito during high temperature and rainfall seasons may be an important strategy for containing the burden of dengue fever.
Matching RDF Graphs

RDF, graph isomorphism, equality The Resource Description Framework (RDF) describes graphs of statements about resources. This paper explores the equality of two RDF graphs in light of the graph isomorphism literature. We consider anonymous resources as unlabelled vertices in a graph, and show that the standard graph isomorphism algorithms, developed in the 1970's, can be used effectively for comparing RDF graphs.
Increase in Daily Steps After an Exercise Specialist Led Lifestyle Intervention for Adults With Type 2 Diabetes In Primary Care: A Controlled Implementation Trial.

OBJECTIVE
To determine the effectiveness of an exercise specialist led lifestyle program for adults with type 2 diabetes in primary care.


METHODS
Eligible participants from 4 primary care networks in Alberta, Canada were assigned to either a lifestyle program or a control group. The program targeted increased daily walking through individualized daily pedometer step goals for the first 3 months and brisk walking speed, along with substitution of low-relative to high-glycemic index foods over the next 3 months. The outcomes were daily steps, diet, and clinical markers, and were compared using random effects models.


RESULTS
198 participants were enrolled (102 in the intervention and 96 in the control). For all participants, (51% were women), mean age 59.5 (SD 8.3) years, A1c 6.8% (SD 1.1), BMI 33.6 kg/m(2) (SD 6.5), systolic BP 125.6 mmHg (SD 16.2), glycemic index 51.7 (4.6), daily steps 5879 (SD 3130). Daily steps increased for the intervention compared with the control at 3-months (1292 [SD 2698] vs. 418 [SD 2458] and 6-months (1481 [SD 2631] vs. 336 [SD 2712]; adjusted P = .002). No significant differences were observed for diet or clinical outcomes.


CONCLUSIONS
A 6-month lifestyle program delivered in primary care by an exercise specialist can be effective for increasing daily walking among adults with recently diagnosed type 2 diabetes. This short-term increase in daily steps requires longer follow-up to estimate the potential impact on health outcomes.
A practice-based randomized controlled trial to improve medication adherence among Latinos with hypertension: study protocol for a randomized controlled trial

BACKGROUND
Latinos experience disproportionately higher rates of uncontrolled hypertension as compared to Blacks and Whites. While poor adherence is a major contributor to disparities in blood pressure control, data in Latino patients are scant. More importantly, translation of interventions to improve medication adherence in community-based primary care practices, where the majority of Latino patients receive their care is non-existent.


METHODS
Using a randomized controlled design, this study evaluates the effectiveness of a culturally tailored, practice-based intervention compared to usual care on medication adherence, among 148 Latino patients with uncontrolled hypertension who are non-adherent to their antihypertensive medications. Bilingual medical assistants trained as Health Coaches deliver the intervention using an electronic medical record system-embedded adherence script. Patients randomized to the intervention group receive patient-centered counseling with a Health Coach to develop individualized self-monitoring strategies to overcome barriers and improve adherence behaviors. Health Coach sessions are held biweekly for the first 3 months (6 sessions total) and then monthly for the remaining 3 months (3 sessions total). Patients randomized to the usual care group receive standard hypertension treatment recommendations as determined by their primary care providers. The primary outcome is the rate of medication adherence at 6 months. The secondary outcome is reduction in systolic and diastolic blood pressure at 6 months.


DISCUSSION
If successful, findings from this study will provide salient information on the translation of culturally tailored, evidence-based interventions targeted at medication adherence and blood pressure control into practice-based settings for this high-risk population.


TRIAL REGISTRATION
NCT01643473 on 16 July 2012.
Post mastectomy adjuvant radiotherapy in breast cancer: a comparision of three hypofractionated protocols.

OBJECTIVES
To compare three hypofractionated protocols in postmastectomy cancinoma breast in terms of local control, toxicity and work load.


METHODS
A total of three hundred patients suffering from cancer breast stage T2-4, N any were randomized into three arms after mastectomy. All the patients were treated with four fields on Co60 i.e. two tangential portals for chest wall, one anterior supraclavicular and axillary field and a posterior axillary boost and were randomized into three arms i.e. 2700 CGy in 5 fractions (one week) arm A, 3500 CGy in 10 fractions (2 weeks) arm B and 4000 CGy in 15 fractions (3 weeks) arm C. Skin, cardiac, pulmonary and haematological toxicities and lymphoedema were compared in addition to local control and work load.


RESULTS
The locoregional relapses were 11%, 12% and 10% in arms A, B and C respectively. 26%, 24% and 28% patients developed metastatic disease and 17%, 18% and 20% died in the three arms. G3 and G4 skin toxicities were 37%, 28% and 14%. G2 and G3 lymphedoema was 21%, 22% and 27%. Cardiac toxicity was 5%, 6% and 5% while pulmonary toxicity was 4%, 5% and 5% respectively. All the differences except skin toxicity were statistically insignificant. There were no cases of haematological depression or rib fractures.


CONCLUSION
All the three short protocols were equally effective in locoregional disease control and toxicity was also comparable. They were helpful in reducing the work load and can be safely recommended for routine clinical use.
Ensemble learning methods for pay-per-click campaign management

http://dx.doi.org/10.1016/j.eswa.2015.01.047 0957-4174/ 2015 Elsevier Ltd. All rights reserved. ⇑ Corresponding author at: Department of Business Information Technology, Virginia Polytechnic Institute and State University, Blacksburg, VA, USA. Tel.: +1 540 231 6596. E-mail addresses: michael.king@vt.edu (M.A. King), abra@vt.edu (A.S. Abrahams), cliff.ragsdale@vt.edu (C.T. Ragsdale). Michael A. King ⇑, Alan S. Abrahams, Cliff T. Ragsdale
Tensile properties of commonly used prolapse meshes

To improve our understanding of the differences in commonly used synthetic prolapse meshes, we compared four newer generation meshes to Gynecare PS™ using a tensile testing protocol. We hypothesize that the newer meshes have inferior biomechanical properties. Meshes were loaded to failure (n = 5 per group) generating load–elongation curves from which the stiffness, the load at failure, and the relative elongation were determined. Additional mesh samples (n = 3) underwent a cyclic loading protocol to measure permanent elongation in response to subfailure loading. With the exception of Popmesh, which displayed uniform stiffness, other meshes were characterized by a bilinear behavior. Newer meshes were 70–90% less stiff than Gynecare™ (p < 0.05) and more readily deformed in response to uniaxial and cyclical loading (p < 0.001). Relative to Gynecare™, the newer generation of prolapse meshes were significantly less stiff, with irreversible deformation at significantly lower loads.
Bronchial hyperactivity, sputum analysis and skin prick test to inhalant allergens in patients with symptomatic food hypersensitivity.

BACKGROUND
Dyspnea may be a presenting symptom of type I food hypersensitivity; bronchial hyperactivity, without known asthma, can coexist in patients with food allergy.


OBJECTIVE
To evaluate airway involvement in young adult patients with food allergy and no asthma and compare the findings to those of patients with food allergy and asthma, with food allergy and allergic rhinitis, with asthma and no food allergy, and of apparently healthy controls.


METHODS
The evaluation involved prick skin test to food (65 allergens) and inhalants (24 allergens), spirometry, methacholine inhalation challenge, and induced sputum for cell analysis. The five groups consisted of 18 patients with food allergy alone, 11 with food allergy and asthma, 13 with food allergy and allergic rhinitis, 10 with asthma alone, and 10 controls.


RESULTS
Patients with food allergy alone were mainly (86%) skin sensitive to pollens. Those with either asthma or allergic rhinitis were mainly (95%) sensitive to mites. BHR was detected in 40% of the patients with food allergy alone, 55% of the patients with allergic rhinitis, and 100% of the patients with asthma. Cell counts in the sputum of patients with asthma and in those with food allergy and asthma showed higher eosinophil counts compared to those with food allergy and allergic rhinitis. Patients with food allergy and no asthma, regardless of BHR status, had mainly neutrophils in the sputum.


CONCLUSIONS
Patients with food allergy are highly likely to have concomitant asymptomatic BHR. Mite sensitivity in patients with food allergy predicts respiratory allergy (either asthma or allergic rhinitis). High eosinophil levels in the sputum of food allergy patients predict respiratory involvement.
Detection of Small Bowel Mucosal Healing and Deep Remission in Patients With Known Small Bowel Crohn’s Disease Using Biomarkers, Capsule Endoscopy, and Imaging

Objectives:Mucosal healing (MH) and deep remission (DR) are associated with improved outcomes in Crohn’s disease (CD). However, most of the current data pertain to colonic MH and DR, whereas the evidence regarding the prevalence and impact of small bowel (SB) MH is scarce. The aim of this study was to to evaluate the prevalence of SBMH and DR in quiescent SBCD.Methods:Patients with known SBCD in clinical remission (CDAI<150) or with mild symptoms (CDAI<220) were prospectively recruited and underwent video capsule endoscopy after verification of SB patency. Inflammation was quantified using the Lewis score (LS). SBMH was defined as LS<135, whereas a significant inflammation was defined as LS>790. Clinico-biomarker remission was defined as a combination of clinical remission and normal biomarkers. DR was defined as a combination of clinico-biomarker remission and MH.Results:Fifty-six patients with proven SB patency were enrolled; 52 (92.9%) patients were in clinical remission and 21 (40.4%) in clinico-biomarker remission. SBMH was demonstrated in 8/52 (15.4%) of patients in clinical remission. Moderate-to-severe SB inflammation was demonstrated in 11/52 (21.1%) of patients in clinical remission and in 1/21 (4.7%) of patients in clinical and biomarker remission. Only 7/52 (13.5%) patients were in DR.Conclusions:SB inflammation is detected in the majority of CD patients in clinical and biomarker remission. SBMH and DR were rare and were independent of treatment modality. Our findings represent the true inflammatory burden in quiescent patients with SBCD.
Dosimetric comparison of doses to organs at risk using 3-D conformal radiotherapy versus intensity modulated radiotherapy in postoperative radiotherapy of periampullary cancers: implications for radiation dose escalation.

CONTEXT
Postoperative periampullary cancers with high risk features are managed with adjuvant chemo radiotherapy. Doses of 40-50 Gy have generally been used in conventional radiotherapy. Dose escalation with conventional radiotherapy has been restricted due to surrounding critical organs.


OBJECTIVE
The objective of this dosimetric analysis was to evaluate the dose of radiation received by organs at risk using 3D conformal radiotherapy (3DCRT) and intensity modulated radiotherapy (IMRT).


METHODS
Ten postoperative patients of periampullary cancers were selected for this dosimetric analysis. Planning CT scans films were taken with slice thickness of 2.5 mm and transferred to Eclipse treatment planning system. The clinical target volume (CTV) included the postoperative tumor bed and draining lymph nodal areas. A 1 cm margin was taken around the CTV to generate the planning target volume (PTV). Critical structures contoured for evaluation included bowel bag, bilateral kidneys, liver, stomach and spinal cord. IMRT plans were generated using seven field coplanar beams and 3DCRT planning was done using one anterior and two lateral fields. A dose of 45 Gy in 25 fractions was prescribed to the PTV.


RESULTS
V45 for bowel bag was 212.3 ± 159.0 cc (mean volume ± standard deviation) versus 80.9 ± 57.4 cc in 3DCRT versus IMRT (P=0.033). The V28 dose analysis for bilateral kidneys showed a value of 32.7±23.5 cc (mean volume ± standard deviation) versus 7.9 ± 7.4 cc for 3DCRT versus IMRT, respectively (P=0.013). The D60 for liver using 3DCRT and IMRT was 28.4 ± 8.6 Gy (mean dose ± standard deviation) and 19.9 ± 3.2 Gy, respectively (P=0.020).


CONCLUSIONS
Doses to bowel bag, liver and kidneys was significantly reduced using IMRT leaving ample scope for dose escalation.
The Influence of Vertical and Horizontal Habitat Structure on Nationwide Patterns of Avian Biodiversity

—With limited resources for habitat conservation, the accurate identification of high-value avian habitat is crucial. Habitat structure affects avian biodiversity but is difficult to quantify over broad extents. Our goal was to identify which measures of vertical and horizontal habitat structure are most strongly related to patterns of avian biodiversity across the conterminous United States and to determine whether new measures of vertical structure are complementary to existing, primarily horizontal, measures. For 2,546 North American Breeding Bird Survey routes across the conterminous United States, we calculated canopy height and biomass from the National Biomass and Carbon Dataset (NBCD) as measures of vertical habitat structure and used land-cover composition and configuration metrics from the 2001 National Land Cover Database (NLCD) as measures of horizontal habitat structure. Avian species richness was calculated for each route for all birds and three habitat guilds. Avian species richness was significantly related to measures derived from both the NBCD and NLCD. The combination of horizontal and vertical habitat structure measures was most powerful, yielding high R2 values for nationwide models of forest (0.70) and grassland (0.48) bird species richness. New measures of vertical structure proved complementary to measures of horizontal structure. These data allow the efficient quantification of habitat structure over broad scales, thus informing better land management and bird conservation. Received 10 January 2013, accepted 30 September 2013.
Restoration of Hearing in the VGLUT3 Knockout Mouse Using Virally Mediated Gene Therapy

Mice lacking the vesicular glutamate transporter-3 (VGLUT3) are congenitally deaf due to loss of glutamate release at the inner hair cell afferent synapse. Cochlear delivery of VGLUT3 using adeno-associated virus type 1 (AAV1) leads to transgene expression in only inner hair cells (IHCs), despite broader viral uptake. Within 2 weeks of AAV1-VGLUT3 delivery, auditory brainstem response (ABR) thresholds normalize, along with partial rescue of the startle response. Lastly, we demonstrate partial reversal of the morphologic changes seen within the afferent IHC ribbon synapse. These findings represent a successful restoration of hearing by gene replacement in mice, which is a significant advance toward gene therapy of human deafness.
Energy-Efficient, Large-Scale Distributed-Antenna System (L-DAS) for Multiple Users

Large-scale distributed-antenna system (L-DAS) with very large number of distributed antennas, possibly up to a few hundred antennas, is considered. A few major issues of the L-DAS, such as high latency, energy consumption, computational complexity, and large feedback (signaling) overhead, are identified. The potential capability of the L-DAS is illuminated in terms of an energy efficiency (EE) throughout the paper. We firstly and generally model the power consumption of an L-DAS, and formulate an EE maximization problem. To tackle two crucial issues, namely the huge computational complexity and large amount of feedback (signaling) information, we propose a channel-gain-based antenna selection (AS) method and an interference-based user clustering (UC) method. The original problem is then split into multiple subproblems by a cluster, and each cluster's precoding and power control are managed in parallel for high EE. Simulation results reveal that i) using all antennas for zero-forcing multiuser multiple-input multiple-output (MU-MIMO) is energy inefficient if there is nonnegligible overhead power consumption on MU-MIMO processing, and ii) increasing the number of antennas does not necessarily result in a high EE. Furthermore, the results validate and underpin the EE merit of the proposed L-DAS complied with the AS, UC, precoding, and power control by comparing with non-clustering L-DAS and colocated antenna systems.
Experiences with node virtualization for scalable network emulation

During the development of network protocols and distributed applications, their performance has to be analyzed in appropriate environments. Network emulation testbeds provide a synthetic, configurable network environment for comparative performance measurements of real implementations. Realistic scenarios have to consider hundreds of communicating nodes. Common network emulation approaches limit the number of nodes in a scenario to the number of computers in an emulation testbed. To overcome this limitation, we introduce a virtual node concept for network emulation. The key problem for node virtualization is a transparent, yet efficient separation of node resources. In this paper, we provide a brief survey of candidate node virtualization approaches to facilitate scalable network emulation. Based on the gathered insights, we propose a lightweight virtualization solution to achieve maximum scalability and discuss the main points regarding its implementation. We present extensive evaluations that show the scalability and transparency of our approach in both a traditional wired infrastructure-based, and in two wireless ad hoc network emulation scenarios. The measurements indicate that our solution can push the upper limit of emulation scenario sizes by a factor of 10 to 28. Given our emulation testbed consisting of 64 computers, this translates to possible scenario sizes of up to 1792 nodes. In addition to the evaluation of our virtualization approach, we discuss key concepts for controlling comprehensive emulation scenarios to support scalability of our system as a whole.
From Markov Chains to Stochastic Games

Markov chains1 and Markov decision processes (MDPs) are special cases of stochastic games. Markov chains describe the dynamics of the states of a stochastic game where each player has a single action in each state. Similarly, the dynamics of the states of a stochastic game form a Markov chain whenever the players’ strategies are stationary. Markov decision processes are stochastic games with a single player. In addition, the decision problem faced by a player in a stochastic game when all other players choose a fixed profile of stationary strategies is equivalent to an MDP. The present chapter states classical results on Markov chains and Markov decision processes. The proofs use methods that introduce the reader to proofs of more general analog results on stochastic games.