LLukas22/scidocs huggingface dataset:
Motivation and Politics in Executive Compensation

For the past 30 years, economists and management theorists have empirically investigated the compensation of top executives. An issue that has received critical attention is what appears to be a weak link between top executive compensation and performance. In contrast to rational models that have characterized most previous studies, this paper develops a political perspective to explain why the linkage between rewards and performance is weak. Implications for research and management practice are presented.
Ginger (Zingiber officinale Roscoe) and the gingerols inhibit the growth of Cag A+ strains of Helicobacter pylori.

BACKGROUND
Ginger root (Zingiber officinale) has been used traditionally for the treatment of gastrointestinal ailments such as motion sickness, dyspepsia and hyperemesis gravidarum, and is also reported to have chemopreventative activity in animal models. The gingerols are a group of structurally related polyphenolic compounds isolated from ginger and known to be the active constituents. Since Helicobacter pylori (HP) is the primary etiological agent associated with dyspepsia, peptic ulcer disease and the development of gastric and colon cancer, the anti-HP effects of ginger and its constituents were tested in vitro.


MATERIALS AND METHODS
A methanol extract of the dried powdered ginger rhizome, fractions of the extract and the isolated constituents, 6-,8-,10-gingerol and 6-shogoal, were tested against 19 strains of HP, including 5 CagA+ strains.


RESULTS
The methanol extract of ginger rhizome inhibited the growth of all 19 strains in vitro with a minimum inhibitory concentration range of 6.25-50 micrograms/ml. One fraction of the crude extract, containing the gingerols, was active and inhibited the growth of all HP strains with an MIC range of 0.78 to 12.5 micrograms/ml and with significant activity against the CagA+ strains.


CONCLUSION
These data demonstrate that ginger root extracts containing the gingerols inhibit the growth of H. pylori CagA+ strains in vitro and this activity may contribute to its chemopreventative effects.
Skype-Hunter: A real-time system for the detection and classification of Skype traffic

In the previous years, Skype has gained more and more popularity, since it is seen as the best VoIP software with good quality of sound, ease of use and one that works everywhere and with every OS. Because of its great diffusion, both the operators and the users are, for different reasons, interested in detecting Skype traffic. In this paper we propose a real-time algorithm (named Skype-Hunter) to detect and classify Skype traffic. In more detail, this novel method, by means of both signature-based and statistical procedures, is able to correctly reveal and classify the signaling traffic as well as the data traffic (calls and file transfers). To assess the effectiveness of the algorithm, experimental tests have been performed with several traffic data sets, collected in different network scenarios. Our system outperforms the ‘classical’ statistical traffic classifiers as well as the state-of-the-art ad hoc Skype classifier. Copyright 2011 John Wiley & Sons, Ltd.
Randomized comparison of 12 or 24 weeks of peginterferon alpha-2a and ribavirin in chronic hepatitis C virus genotype 2/3 infection.

UNLABELLED
Previous trials investigating the efficacy of treatment durations shorter than the standard of 24 weeks for chronic hepatitis C virus (HCV) genotype 2/3 infections have yielded discordant results. The aims of this investigator-initiated phase III study were to compare the efficacy of 12 or 24 weeks of treatment and to identify patients suitable for short-term therapy. Three hundred eighty-two genotype 2/3-infected patients [intention-to-treat (ITT) population] at 31 centers in Denmark, Finland, Norway, and Sweden were randomized to 12 or 24 weeks of peginterferon alpha-2a (180 microg/week) plus ribavirin (800 mg/day). Twelve weeks of therapy was inferior to 24 weeks in the ITT population (sustained viral response [SVR] rates: 59% versus 78%, P < 0.0001) and in the subgroups of patients infected with genotype 2 (56% versus 82%, P = 0.006) or 3 (58% versus 78%, P = 0.0015). These differences were observed regardless of the fibrosis stage. Age and HCV-RNA levels on days 7 and 29 were independent predictors of SVR. Short-term treatment was useful in patients < 40 years old, especially if HCV-RNA was undetectable on day 29, and also in patients > or = 40 years old, provided that HCV-RNA was below 1000 IU/mL on day 7 in addition to being undetectable on day 29. If neither of these two criteria were met for patients > or = 40 years old, 24 weeks of therapy was superior (P < 0.0001).


CONCLUSION
Peginterferon/ribavirin treatment for 12 weeks in HCV genotype 2/3 infection is overall inferior to 24 weeks of treatment but may be useful in some patients with a rapid initial clearance of virus.
Study on the clinical significance and related factors of thirst and xerostomia in maintenance hemodialysis patients.

AIMS
To analyse the clinical significance and related factors of thirst and xerostomia and to find methods to alleviate thirst and xerostomia in maintenance hemodialysis (MHD) patients.


METHODS
Forty-two MHD patients were included for observational study and eleven patients were enrolled for crossover trial. Thirst was assessed by 100-mm visual analog scales (VAS) and dialysis thirst inventory (DTI). Meanwhile, xerostomia was assessed by VAS and xerostomia inventory (XI). Depression, kidney disease quality of life (KDQOL), salivary flow rates and inter dialytic weight gain (IDWG) were measured. Data were analyzed by ANOVA and correlation coefficient was used to assess the correlations between continuous variables. The results of crossover trial were investigated by two-sample T-tests.


RESULTS
Strong positive correlations among DTI, VAS thirst score, XI and VAS xerostomia score were found (P=0.000). Daily IDWG was positively correlated with VAS thirst score (r=0.315, P=0.042) and DTI(r=0.391, P=0.010). UWS (unstimulated whole saliva) was negatively correlated with VAS xerostomia score (r=-0.308, P=0.048). Residual urine output was negatively correlated with DTI (r=-0.402, P=0.008), VAS xerostomia score (r=-0.461, P=0.002) and XI (r=-0.403, P=0.008). In the crossover trial, DTI, XI, IDWG2d, IDWG3d, VAS thirst and xerostomia score were significantly reduced by the use of chewing gum (P=0.000, 0.001, 0.009, 0.017, 0.038, 0.001). The VAS thirst score, DTI and IDWG3d were significantly reduced by receiveing straw (P=0.016, 0.003, 0.049).


CONCLUSION
Thirst and xerostomia might affect the quality of life in MHD patients. Both chewing gum and straw could decrease thirst and IDWG.
Impact of structural and psychological empowerment on job strain in nursing work settings: expanding Kanter's model.

OBJECTIVE
In this study, we tested an expanded model of Kanter's structural empowerment, which specified the relationships among structural and psychological empowerment, job strain, and work satisfaction.


BACKGROUND
Strategies proposed in Kanter's empowerment theory have the potential to reduce job strain and improve employee work satisfaction and performance in current restructured healthcare settings. The addition to the model of psychological empowerment as an outcome of structural empowerment provides an understanding of the intervening mechanisms between structural work conditions and important organizational outcomes.


METHODS
A predictive, nonexperimental design was used to test the model in a random sample of 404 Canadian staff nurses. The Conditions of Work Effectiveness Questionnaire, the Psychological Empowerment Questionnaire, the Job Content Questionnaire, and the Global Satisfaction Scale were used to measure the major study variables.


RESULTS
Structural equation modelling analyses revealed a good fit of the hypothesized model to the data based on various fit indices (chi 2 = 1140, df = 545, chi 2/df ratio = 2.09, CFI = 0.986, RMSEA = 0.050). The amount of variance accounted for in the model was 58%. Staff nurses felt that structural empowerment in their workplace resulted in higher levels of psychological empowerment. These heightened feelings of psychological empowerment in turn strongly influenced job strain and work satisfaction. However, job strain did not have a direct effect on work satisfaction.


CONCLUSIONS
These results provide initial support for an expanded model of organizational empowerment and offer a broader understanding of the empowerment process.
Does short-term androgen deprivation substitute for radiation dose in the treatment of high-risk prostate cancer?

PURPOSE
Randomized trials have corroborated the clinical benefit of adding androgen deprivation (AD) to radiotherapy (RT) in the treatment of high-risk prostate cancer. Another competing strategy is to escalate the RT dose using three-dimensional conformal RT (3D-CRT). In this analysis, we asked whether the addition of short-term AD (STAD) (<or=6 months) to RT in the treatment of high-risk (prostate-specific antigen >20 ng/mL, Gleason score 8-10, or T3-4) prostate cancer is an effective substitute for dose escalation.


METHODS AND MATERIALS
Between March 1, 1990 and November 30, 1998, 296 high-risk prostate cancer patients were treated with 3D-CRT alone (n = 206) or in combination with STAD (n = 90). The patient characteristics were median age 68 years, median follow-up 58 months, pretreatment initial prostate-specific antigen 21.8 ng/mL, RT dose 75 Gy, STAD duration 3 months, and time off STAD 64 months. The impact of STAD with respect to dose was examined using univariate analysis for dose ranges of <75 Gy and >or=75 Gy. Stepwise Cox proportional hazards regression multivariate analysis was performed to determine independent correlates of freedom from biochemical failure (bNED), freedom from distant metastasis (FDM), and overall survival. In a separate matched-pair analysis (n = 44 per group), those treated to <75 Gy + STAD (Group A) were compared with those who received >or=75 Gy alone (Group B).


RESULTS
On univariate analysis, the addition of STAD had no impact on bNED, FDM, or overall survival in either dose group. On multivariate analysis, initial prostate-specific antigen level, palpation T stage, and RT dose were significant correlates of bNED. For FDM and overall survival, the significant covariates were palpation T stage and Gleason score, respectively. Finally, in matched-pair analysis, the higher RT dose group had a significantly greater bNED rate at 5 years (Group A 35% vs. Group B 57%, p = 0.0190).


CONCLUSION
Our data suggest that STAD, as used here (median 3 months), is not a substitute for RT dose in the treatment of high-risk prostate cancer. RT dose is an essential element in the treatment of high-risk prostate cancer.
Entanglement Entropy and Quantum Field Theory

We carry out a systematic study of entanglement entropy in relativistic quantum field theory. This is defined as the von Neumann entropy SA = −Tr ρA log ρA corresponding to the reduced density matrix ρA of a subsystem A. For the case of a 1+1-dimensional critical system, whose continuum limit is a conformal field theory with central charge c, we re-derive the result SA ∼ (c/3) log l of Holzhey et al. when A is a finite interval of length l in an infinite system, and extend it to many other cases: finite systems, finite temperatures, and when A consists of an arbitrary number of disjoint intervals. For such a system away from its critical point, when the correlation length ξ is large but finite, we show that SA ∼ A(c/6) log ξ, where A is the number of boundary points of A. These results are verified for a free massive field theory, which is also used to confirm a scaling ansatz for the case of finite-size off-critical systems, and for integrable lattice models, such as the Ising and XXZ models, which are solvable by corner transfer matrix methods. Finally the free-field results are extended to higher dimensions, and used to motivate a scaling form for the singular part of the entanglement entropy near a quantum phase transition. Typeset using REVTEX Address for correspondence 1
Reliability and validity of the Edinburgh Postnatal Depression Scale (EPDS) for detecting perinatal common mental disorders (PCMDs) among women in low-and lower-middle-income countries: a systematic review.

BACKGROUND
The Edinburgh Postnatal Depression Scale (EPDS), originally developed in Britain, is one of the most widely used screening instruments for assessing symptoms of the Perinatal Common Mental Disorders (PCMDs) of depression and anxiety. However, its potential to detect PCMDs in culturally diverse low- and lower-middle income countries (LALMICs) is unclear. This systematic review aimed to appraise formally validated local language versions of the EPDS from these resource-constrained settings.


METHODS
Following the PRISMA protocol, we searched MEDLINE-OVID, CINAHL-Plus and PUBMED to identify studies reporting translation, cultural adaptation and formal validation of the EPDS to detect PCMDs among women in LALMICs. The quality of the studies meeting inclusion criteria was assessed using standard criteria and a new process-based criteria; which was developed specifically for this study.


RESULTS
We identified 1281 records among which 16 met inclusion criteria; three further papers were identified by hand-searching reference lists. The publications reported findings from 12 LALMICs in 14 native languages. Most of these local language versions of the EPDS (LLV-EPDS) had lower precision for identifying true cases of PCMDs among women in the general perinatal population compared to the original English version. Only one study met all criteria for culturally sensitive translation, the others had not established the comprehensibility of the local version amongst representative groups of women in pre-testing. Many studies tested the LLV-EPDS only amongst convenience samples recruited at single health facilities. Diagnostic interviews for confirmation of mental disorders could have been influenced by the mental health professionals' lack of blinding to the initial screening results. Additionally, even when diagnostic-interviews were carried out in the local language, questions might not have been understood as most studies followed standard diagnostic protocol which had not been culturally adapted.


CONCLUSIONS
Most of the LLV-EPDS from non-English speaking low- and middle-income-countries did not meet all criteria for formal validation of a screening instrument. Psychometric properties of LLV-EPDS could be enhanced by adopting the new process-based criteria for translation, adaptation and validation.
Assessment of spatial distribution and potential ecological risk of the heavy metals in relation to granulometric contents of Veeranam lake sediments, India.

The contents and spatial distributions of heavy metals (Cd, Cr, Cu, Ni, Pb and Zn) have been studied in surface sediments of Veeranam lake, Tamilnadu, India. Heavy metal contents are higher in open water area (limnetic zone) (OWA) than other two regions such as inflow river mouth (littoral zone) (IFR) and outflow river mouth region (OFR). Present metal contents are compared with both background and toxicological reference values. The comparative results suggest that the present metals except Cd and Pb create an adverse effect on the aquatic ecosystems associated with this lake. The Pollution Load Index (PLI) and Potential Ecological Risk (PER) are calculated and calculated PLI values (range: 1.18-4.09 with an average of 2.03) show that the present sediments are polluted significantly and these values are higher in OWA region. From the PER values, each single element has low potential ecological risk. However, Cd shows higher ecological risk. The comprehensive PER index of the sediments shows moderate degree. The magnetic susceptibility is higher in OWA region. Granulometric analysis confirms that the silt is major content. Multivariate Statistical analyses (Pearson Correlation, Cluster and Factor analysis) were carried out and obtained results suggested that the heavy metals in present lake have complicated contamination sources or controlling factors and the heavy metals such as Cr, Cu, Ni and Zn may be incorporated in magnetic minerals which are presented in silt grains. Also it shows that the role of silt is incorporating the cations on their surface and raising the level of magnetic susceptibility and heavy metal contents. The present study recommends that the heavy metal levels are unlikely to cause additional adverse health risks to the aquatic ecosystem associated with this lake.
Deformed lattice structure of C 60 3

Abstract Using a tight-binding model with electron-phonon coupling based on the modified Su-Schriffer-Heeger model Hamiltonian, we obtained the deformed lattice structures for C 60 3− which is charge-transfer state for superconducting M 3 C 60 compounds. The deformed structures are C i ( λ =0.1, 0.3) and C 2v ( λ =0.5), which are different to D 5d of C 60 1− in the same values of λ. Here λ means the dimensionless coupling constant (S 2 /KT). We also have shown the bond length difference between C 60 3− and C 60 .
A quantile-quantile plot based pattern matching for defect detection

Pattern matching has been used extensively for many machine vision applications such as optical character recognition, face detection, object detection, and defect detection. The normalized cross correlation (NCC) is the most commonly used technique in pattern matching. However, it is computationally intensive, sensitive to environmental changes such as lighting and shifting, and suffers from false alarms for a complicated image that contains partial uniform regions. In this paper, a pattern matching scheme based on the quantile-quantile plot (Q-Q plot) is proposed for defect detection applications. In a Q-Q plot, the quantiles of an inspection image are plotted against the corresponding quantiles of the template image. The p-value of Chi-square test from the resulting Q-Q plot is then used as the quantitative measure of similarity between two compared images. The quantile representation transforms the 2D gray-level information into the 1D quantile one. It can therefore efficiently reduce the dimensionality of the data, and accelerate the computation. Experimental results have shown that the proposed pattern matching scheme is computationally fast and is tolerable to minor displacement and process variation. The proposed similarity measure of p-value has excellent discrimination capability to detect subtle defects, compared with the traditional measure of NCC. With a proper normalization of the Q-Q plot, the p-value measure can be tolerable to moderate light changes. Experimental results from assembled PCB (printed circuit board) samples, IC wafers, and LCD (liquid crystal display) panels have shown the efficacy of the proposed pattern matching scheme for defect detection.
Chemogenetic stimulation of the infralimbic cortex reverses alcohol-induced fear memory overgeneralization

Post-traumatic stress disorder (PTSD) and alcohol use disorder (AUD) are often comorbid. Drinking tends to increase following trauma, which may exacerbate PTSD-related symptoms. Despite a clear relationship between excessive alcohol use and PTSD, how alcohol impacts the expression of traumatic fear remains unclear. This study aims to determine the neurobehavioral impact of chronic alcohol (ethanol; EtOH) on the expression of established fear memories in C57BL/6 N mice. We show that chronic EtOH selectively augments cued fear memory generalization and impairs fear extinction retrieval, leaving the expression of the original cued response intact. Immunohistochemistry for Arc/arg3.1 (Arc) revealed EtOH-induced decreases in Arc expression in the infralimbic cortex (IL) and basolateral amygdala complex (BLA) that were associated with cued fear memory overgeneralization. Chemogenetic stimulation of IL pyramidal neurons reversed EtOH-driven fear memory overgeneralization, identifying a role for the IL in cued fear memory precision. Considering the modulatory influence of the IL over conditioned fear expression, these data suggest a model whereby chronic EtOH-driven neuroadaptations in the IL promote fear memory overgeneralization. These findings provide new mechanistic insight into how excessive alcohol use, following exposure to a traumatic event, can exacerbate symptoms of traumatic fear.
Association of a presenilin 1 S170F mutation with a novel Alzheimer disease molecular phenotype.

OBJECTIVE
To report an ataxic variant of Alzheimer disease expressing a novel molecular phenotype.


DESIGN
Description of a novel phenotype associated with a presenilin 1 mutation.


SETTING
The subject was an outpatient who was diagnosed at the local referral center.


PATIENT
A 28-year-old man presented with psychiatric symptoms and cerebellar signs, followed by cognitive dysfunction. Severe beta-amyloid (Abeta) deposition was accompanied by neurofibrillary tangles and cell loss in the cerebral cortex and by Purkinje cell dendrite loss in the cerebellum. A presenilin 1 gene (PSEN1) S170F mutation was detected.


MAIN OUTCOME MEASURES
We analyzed the processing of Abeta precursor protein in vitro as well as the Abeta species in brain tissue.


RESULTS
The PSEN1 S170F mutation induced a 3-fold increase of both secreted Abeta(42) and Abeta(40) species and a 60% increase of secreted Abeta precursor protein in transfected cells. Soluble and insoluble fractions isolated from brain tissue showed a prevalence of N-terminally truncated Abeta species ending at both residues 40 and 42.


CONCLUSION
These findings define a new Alzheimer disease molecular phenotype and support the concept that the phenotypic variability associated with PSEN1 mutations may be dictated by the Abeta aggregates' composition.
AGV Localization and Navigation System using Bluetooth GPS

Localization and navigation technology is one of the key technologies for Automated Guided Vehicle (AGV). In this paper we develop an AGV navigation system utilizing commercial Bluetooth GPS. WGS-84 coordinates system is converted to space rectangular coordinate system, which is combined with orientation information, initial position and gesture of AGV can be determined. Experimental result shows that the localization accuracy can meet the demand.
Integrating sex and attachment in emotionally focused couple therapy.

In this article, sexual functioning is placed in the context of love as an attachment bond. Attachment theory offers the most coherent and empirically validated theory of adult love and is summarized together with the implications of this theory for the practice of couple therapy in which sexual issues are often addressed. Recent research on attachment and sexuality is outlined and a model of healthy sexuality where attachment and sexuality are integrated is offered. The principles of an attachment-oriented approach to sex issues are set out and illustrated with reference to the process of emotionally focused couple therapy. Case descriptions and brief in-session transcripts are included.