LLukas22/scidocs huggingface dataset:
Finding Synonyms Using Automatic Word Alignment and Measures of Distributional Similarity

There have been many proposals to extract semantically related words using measures of distributional similarity, but these typically are not able to distinguish between synonyms and other types of semantically related words such as antonyms, (co)hyponyms and hypernyms. We present a method based on automatic word alignment of parallel corpora consisting of documents translated into multiple languages and compare our method with a monolingual syntax-based method. The approach that uses aligned multilingual data to extract synonyms shows much higher precision and recall scores for the task of synonym extraction than the monolingual syntax-based approach.
Proximal superficial femoral artery occlusion, collateral vessels, and walking performance in peripheral artery disease.

OBJECTIVES
We studied associations of magnetic resonance imaging (MRI)-measured superficial femoral artery (SFA) occlusions with functional performance, leg symptoms, and collateral vessel number in peripheral artery disease (PAD). We studied associations of collateral vessel number with functional performance in PAD.


BACKGROUND
Associations of MRI-detected SFA occlusion and collateral vessel number with functional performance among individuals with PAD have not been reported.


METHODS
A total of 457 participants with an ankle brachial index (ABI) <1.00 had MRI measurement of the proximal SFA with 12 consecutive 2.5-μm cross-sectional images. An occluded SFA was defined as an SFA in which at least 1 segment was occluded. A nonoccluded SFA was defined as absence of any occluded slices. Collateral vessels were visualized with magnetic resonance angiography. Lower extremity functional performance was measured with the 6-min walk, 4-m walking velocity at usual and fastest pace, and the Short Physical Performance Battery (SPPB) (0 to 12 scale, 12 = best).


RESULTS
Adjusting for age, sex, race, comorbidities, and other confounders, the presence of an SFA occlusion was associated with poorer 6-min walk performance (1,031 vs. 1,169 feet, p = 0.006), slower fast-paced walking velocity (1.15 vs. 1.22 m/s, p = 0.042), and lower SPPB score (9.07 vs. 9.75, p = 0.038) compared with the absence of an SFA occlusion. More numerous collateral vessels were associated with better 6-min walk performance (0 to 3 collaterals-1,064 feet, 4 to 7 collaterals-1,165 feet, ≥8 collaterals-1,246 feet, p trend = 0.007), faster usual-paced walking speed (0 to 3 collaterals-0.84 m/s, 4 to 7 collaterals-0.88 m/s, ≥8 collaterals-0.91 m/s, p trend = 0.029), and faster rapid-paced walking speed (0 to 3 collaterals-1.17 m/s, 4 to 7 collaterals-1.22 m/s, ≥8 collaterals-1.29 m/s, p trend = 0.002), adjusting for age, sex, race, comorbidities, ABI, and other confounders.


CONCLUSIONS
Among PAD participants, MRI-visualized occlusions in the proximal SFA are associated with poorer functional performance, whereas more numerous collaterals are associated with better functional performance. (Magnetic Resonance Imaging to Identify Characteristics of Plaque Build-Up in People With Peripheral Arterial Disease; NCT00520312).
Nitric oxide in chronic airway inflammation in children: diagnostic use and pathophysiological significance.

BACKGROUND
The levels of exhaled and nasal nitric oxide (eNO and nNO) in groups of patients with inflammatory lung diseases are well documented but the diagnostic use of these measurements in an individual is unknown.


METHODS
The levels of nNO and eNO were compared in 31 children with primary ciliary dyskinesia (PCD), 21 with non-CF bronchiectasis (Bx), 17 with cystic fibrosis (CF), 35 with asthma (A), and 53 healthy controls (C) using a chemiluminescence NO analyser. A diagnostic receiver-operator characteristic (ROC) curve for PCD using NO was constructed.


RESULTS
The median (range) levels of nNO in parts per billion (ppb) in PCD, Bx, CF, and C were 60.3 (3.3-920), 533.6 (80-2053), 491.3 (31-1140), and 716 (398-1437), respectively; nNO levels were significantly lower in PCD than in all other groups (p<0.05). The median (range) levels of eNO in ppb in PCD, Bx, CF, A, and C were 2.0 (0.2-5.2), 5.4 (1.0-22.1), 2.6 (0.8-12.9), 10.7 (1.6-46.7), and 4.85 (2.5-18.3), respectively. The difference in eNO levels in PCD reached significance (p<0.05) when compared with those in Bx, A and C but not when compared with CF. Using the ROC curve, nNO of 250 ppb showed a sensitivity of 97% and a specificity of 90% for the diagnosis of PCD.


CONCLUSIONS
eNO and nNO cannot be used diagnostically to distinguish between most respiratory diseases. However, nNO in particular is a quick and useful diagnostic marker which may be used to screen patients with a clinical suspicion of PCD.
Performance of electrical discharge machining using aluminium powder suspended distilled water

This paper presents the experimental investigations on addition of aluminium metal powder to dielectric fluid in electric discharge machining (EDM). As more emphasis is given nowadays to the green manufacturing concept, the present investigation uses distilled water mixed with aluminium powder as dielectric fluid instead of conventional hydrocarbon-based oils. The workpiece and electrode materials chosen for the investigation are W300 die-steel and electrolytic copper, respectively. Taguchi design of experiments is used to conduct experiments by varying the parameters peak current, pulse on-time, concentration of the powder, and polarity. The process performance is measured in terms of material removal rate (MRR), electrode wear ratio (EWR), average surface roughness (Ra), and white layer thickness (WLT). The experimental results indicate that the polarity significantly affects the machining performance. Signal-to-noise (S/N) ratio and the analysis of variance (ANOVA) are employed to find the optimal levels for the process parameters to achieve maximum MRR, low EWR, Ra, and WLT values.
Implementing a patient-initiated review system for people with rheumatoid arthritis: a prospective, comparative service evaluation.

RATIONALE, AIMS AND OBJECTIVES
The management of rheumatoid arthritis (RA) usually entails regular hospital reviews with a specialist often when the patient is well rather than during a period of exacerbation. An alternative approach where patients initiate appointments when they need them can improve patient satisfaction and resource use whilst being safe. This service evaluation reports a system-wide implementation of a patient-initiated review appointment system called Direct Access (DA) for people with RA. The aim was to establish the impact on patient satisfaction of the new system versus usual care as well as evaluate the implementation processes.


METHODS
As all patients could not start on the new system at once, in order to manage the implementation, patients were randomly allocated to DA or to usual care. Instead of regular follow-up appointments, DA comprised an education session and access to a nurse-led telephone advice line where appointments could be accessed within two weeks. Usual care comprised routine follow-ups with the specialist. Data were collected on patient satisfaction, service use and outcomes of any contact to the advice line.


RESULTS
Three hundred and eleven patients with RA were assessed as being suitable for DA. In terms of patient satisfaction, between-group differences were found in favour of DA for accessibility and convenience, ease of contacting the nurse and overall satisfaction with the service. Self-reported visits to the general practitioner were also significantly lower. DA resulted in a greater number of telephone contacts (incidence rate ratio = 1.69; 95% confidence interval 1.07 to 2.68). Hospital costs of the two different service models were similar. Mean waiting time for an appointment was 10.8 days


CONCLUSION
This service evaluation found that DA could be implemented and it demonstrated patient benefit in a real-world setting. Further research establishing the broader cost-consequences across the whole patient pathway would add to our findings.
Loneliness and Internet use

The Internet is becoming increasingly influential, but some observers have noted that heavy Internet users seem alienated from normal social contacts and may even cut these off as the Internet becomes the predominate social factor in their lives. Kraut, Patterson, Lundmark, Kiesler, Mukopadhyay, and Scherlis [American Psychologist 53 (1998) 65] carried out a longitudinal study from which they concluded that Internet use leads to loneliness among its users. However, their study did not take into account that the population of Internet users is not uniform and comprises many different personality types. People use the Internet in a variety of ways in keeping with their own personal preference. Therefore, the results of this interaction between personality and Internet use are likely to vary among different individuals and similarly the impact on user well-being will not be uniform. One of the personality characteristics that has been found to influence Internet use is that of extroversion and neuroticism [Hamburger & Ben-Artzi, Computers in Human Behavior 16 (2000) 441]. For this study, 89 participants completed questionnaires pertaining to their own Internet use and feelings of loneliness and extroversion and neuroticism. The results were compared to two models (a) the Kraut et al. (1998) model which argues that Internet use leads to loneliness (b) an alternative model which argues that it is those people who are already lonely who spend time on the Internet. A satisfactory goodness of fit was found for the alternative model. Building on these results, several different directions are suggested for continuing research in this field. # 2002 Published by Elsevier Science Ltd.
In vitro penetration properties of solid lipid nanoparticles in intact and barrier-impaired skin.

Treatment of skin diseases implies application of a drug to skin with an impaired epidermal barrier, which is likely to affect the penetration profile of the drug substance as well as the carrier into the skin. To elucidate this, the effect of skin barrier damage on the penetration profile of a corticosteroid applied in solid lipid nanoparticles (SLN) composed of different lipids, varying in polarity, was studied. The studies were carried out in vitro using impaired and intact porcine ear skin, and the SLN were compared with a conventional ointment. It was shown that a significantly higher amount of corticosteroid remained in the skin, intact as well as barrier impaired, when SLN was used as a vehicle. In general, the penetration profile of the drug substance into the skin was affected by the type of lipid used in the formulation and related to lipid polarity and drug substance solubility. When formulated in SLN and applied to intact skin, the permeation of the drug substance across the skin was significantly reduced, as compared to the ointment. Altogether, in both barrier-impaired and intact skin, a higher amount of drug substance remained in the skin during application of SLN for 6, 16, and 24h, as compared to the ointment. These results emphasize the applicability of SLN to create a drug reservoir in skin, with the drug localized distinctively in the stratum corneum.
In Search of the Uncanny Valley

Recent advances in computer animation and robotics have lead to greater and greater realism of human appearance to be obtained both on screen and in physical devices. A particular issue that has arisen in this pursuit is whether increases in realism necessarily lead to increases in acceptance. The concept of the uncanny valley suggests that high, though not perfect, levels of realism will result in poor acceptance. We review this concept and its psychological basis.
Investigation of possible endogenous hypoxia markers in colorectal cancer.

OBJECTIVE
We evaluated the potential of some recently proposed hypoxia markers, being monocarboxylic acid transporter 1 (MCT1), MCT4 and prolyl hydroxylase 2 (PHD2); and a more established hypoxia marker, glucose transporter-1 (GLUT-1), by testing the association with the exogenous marker pimonidazole.


MATERIALS AND METHODS
Paraffin embedded tumour sections of 20 colorectal cancer patients were stained for blood vessels together with either pimonidazole or carbonic anhydrase-IX (CA-IX) and single stained for MCT1, MCT4, GLUT-1, and PHD2. Expression of all markers was compared with expression of pimonidazole and micro-vessel density (MVD) and with disease-free survival (DFS) and overall survival (OS).


RESULTS
No correlation was found between the different intrinsic hypoxia markers tested and pimonidazole. A trend for high MCT1 expression in biopsies with low CA-IX expression was found (R = -0.45, p = 0.06) and also the expression of MCT1 was higher in tumours with a high MVD (R = 0.49, p = 0.04). The more advanced tumours showed a higher expression of GLUT-1 (p = 0.03). A low CA-IX expression in the tumour correlated with better DFS (p = 0.03) and related to better OS (p = 0.07).


CONCLUSION
Although none of the tested intrinsic hypoxia markers correlated with pimonidazole staining, we confirmed the important role of both GLUT-1 and CA-IX for a more advanced pTNM (pathological tumour-node-metastasis) stage and DFS respectively.
A Continuously Growing Dataset of Sentential Paraphrases

A major challenge in paraphrase research is the lack of parallel corpora. In this paper, we present a new method to collect large-scale sentential paraphrases from Twitter by linking tweets through shared URLs. The main advantage of our method is its simplicity, as it gets rid of the classifier or human in the loop needed to select data before annotation and subsequent application of paraphrase identification algorithms in the previous work. We present the largest human-labeled paraphrase corpus to date of 51,524 sentence pairs and the first cross-domain benchmarking for automatic paraphrase identification. In addition, we show that more than 30,000 new sentential paraphrases can be easily and continuously captured every month at ∼70% precision, and demonstrate their utility for downstream NLP tasks through phrasal paraphrase extraction. We make our code and data freely available.1
Effective en-masse retraction design with orthodontic mini-implant anchorage: a finite element analysis.

INTRODUCTION
The strategic design of an appliance for correcting a bialveolar protrusion by using orthodontic mini-implant anchorage and sliding mechanics must take into account the position and height of the mini-implant, the height of the anterior retraction hook and compensating curve, and midline vertical traction. In this study, we used finite element analysis to examine effective en-masse retraction with orthodontic mini-implant anchorage and sought to identify a better combination of the above factors.


METHODS
Base models were constructed from a dental study model. Models with labially and lingually inclined incisors were also constructed. The center of resistance for the 6 anterior teeth in the base model was 9 mm superiorly and 13.5 mm posteriorly from the midpoint of the labial splinting wire. The working archwires were assumed to be 0.019 x 0.025-in or 0.016 x 0.022-in stainless steel. The amount of tooth displacement after finite element analysis was magnified 400 times and compared with central and lateral incisor and canine axis graphs.


RESULTS AND CONCLUSIONS
The tooth displacement tendencies were similar in all 3 models. The height of the anterior retraction hook and the placement of the compensating curve had limited effects on the labial crown torque of the central incisors for en-masse retraction. The 0.016 x 0.022-in stainless steel archwire showed more tipping of teeth compared with the 0.019 x 0.025-in archwire. For high mini-implant traction and 8-mm anterior retraction hook condition, the retraction force vector was applied above the center of resistance for the 6 anterior teeth, but no bodily retraction of the 6 anterior teeth occurred. For high mini-implant traction, 2-mm anterior retraction hook, and 100-g midline vertical traction condition, the 6 anterior teeth were intruded and tipped slightly labially.
Leadership development and school improvement: contemporary issues in leadership development

There is great interest in educational leadership in the early part of the twenty-first century. This is because of the widespread belief that the quality of leadership makes a significant difference to school and student outcomes. In many parts of the world, including both developed and developing countries, there is increasing recognition that schools require effective leaders and managers if they are to provide the best possible education for their students and learners. More governments are realising that their main assets are their people and that remaining, or becoming, competitive depends increasingly on the development of a highly skilled workforce. This requires trained and committed teachers but they, in turn, need the leadership of highly effective principals with the support of other senior and middle managers.
Sexual risk taking, sexually transmitted infections and HIV prevalence among four "high-risk" occupational groups of Indonesian men.

OBJECTIVES
This article reports new surveillance data on the prevalence of sexual risk taking, HIV and other sexually transmitted infections (STI) among four occupational groups of Indonesian men thought to be at elevated risk of infection.


METHODS
Behavioural survey data were collected from 3008 men in 11 cities, among whom 2158 men were tested for HIV and syphilis and 1950 for gonorrhoea and chlamydia. Risk factors for STI were assessed using multivariable logistic regression.


RESULTS
Thirty-six per cent of men had sex with a female sex worker (FSW) in the previous year and 20% with non-marital female partners. Consistent condom use was low with both sex workers (17%) and other non-marital partners (13%). HIV prevalence was 2% in Papua and less than 1% elsewhere, but was for the first time detectable in a non-core transmitter male population outside of Papua. STI rates were high for a non-core transmitter group, especially syphilis. Truck drivers were the most at risk. Multivariable analyses revealed exposure to FSW and inconsistent condom use, along with geographical location (Papua vs non-Papua) and unobserved factors associated with certain occupational groups, to be key risk factors for STI infection.


CONCLUSIONS
The results confirm that men in the four occupational groups are reasonable proxies for "high-risk men" for surveillance purposes in Indonesia. Although HIV prevalence was low, the extent of sexual risk taking and the moderately high levels of STI among these men, along with rising HIV rates among FSW, indicate the potential for HIV/AIDS transmission in Indonesia to accelerate.
Flexible Grid Connection Technique of Voltage-Source Inverter Under Unbalanced Grid Conditions Based on Direct Power Control

This paper proposes a flexible grid connection technique of a voltage-source inverter (VSI) based on a direct power control strategy under unbalanced grid conditions. Based on the mathematical model in the αβ stationary reference frame of the VSI, the generalized power reference compensation expressions for adjustable current unbalance and power fluctuations are deduced. By analyzing the active and reactive power expressions, three different algorithms based on the different control parameters are designed to make a compromise among the current negative sequence, the active power ripples, and the reactive power ripples. To satisfy the grid code, the third-harmonic current component is removed in the proposed flexible control target. Furthermore, the control scheme incorporates multiple complex coefficient filters to separate the positive and negative fundamental components of grid voltage and current to calculate the power reference compensation. The proportional-integral-resonant controller is applied to track the instantaneous power errors. The experimental results verify that the proposed control strategy is adaptive to the flexible control targets.
Introduction: Theology and Rationality Inside Out

The following six articles are revised versions of papers given at a research workshop, ‘‘Theology and Rationality,’’ at the University of Toronto in November 2012. The workshop came about as part of a larger project bearing the same title, launched and carried out by the Department of Systematic Theology and Philosophy of Religion at Goethe University Frankfurt. Promoting and strengthening the ‘‘strategic partnership’’ between (and supported by) both institutions, a follow-up to the Toronto workshop titled ‘‘Rationality Inside Out’’ will be held at Goethe University in October 2013. Here the nature and inter-religious significance of rationality will be discussed both from an internal (intra-religious: Judaism, Christianity, Islam) and external (extraor non-religious) perspective. The six papers presented here cover a fairly wide range of what at first sight might seem rather disparate aspects of the overall theme. However, closer inspection reveals a common focus in guiding interests and in particular topics and methods chosen. As such the papers can be divided into three subgroups. The first two are in large parts, though not exclusively, devoted to the concept of rationality. Heiko Schulz suggests to conceive of the latter as an epistemic virtue-concept, which, other characteristics notwithstanding, is to be placed halfway between virtues that admit being reformulated both as goods and duties (e.g., honesty) and those lacking this capacity (e.g., wisdom). After briefly arguing for a pragmatical, ‘‘success’’-related standard or measure of rationality, theological statements and/or religious beliefs are shown to be epistemically successful and thus rationally justified, at least in principle, if and to the extent that they are rooted in experiences to be spelled out as ‘‘acute spiritual crises.’’ Some theological implications of this view are briefly discussed at the end of the article. A different approach—yielding epistemically similar conclusions—is chosen by Gesche Linde: drawing on selected examples of religious argument across world religions, she outlines a minimum concept of rationality (person-relatedness, structure-relatedness, communicability, generality, differentiatedness), in order subsequently to connect the latter with a semiotic frame theory. This theory invokes Charles Peirce’s analytical system of semiotic trichotomies, which, among other things, allows and calls for distinguishing between different types of rationality. In light