LLukas22/scidocs huggingface dataset:
Trends in esophageal and esophagogastric junction cancer research from 2007 to 2016

BACKGROUND
This study aimed to analyze the scientific outputs of esophageal and esophagogastric junction (EGJ) cancer and construct a model to quantitatively and qualitatively evaluate pertinent publications from the past decade.


METHODS
Publications from 2007 to 2016 were retrieved from the Web of Science Core Collection database. Microsoft Excel 2016 (Redmond, WA) and the CiteSpace (Drexel University, Philadelphia, PA) software were used to analyze publication outcomes, journals, countries, institutions, authors, research areas, and research frontiers.


RESULTS
A total of 12,978 publications on esophageal and EGJ cancer were identified published until March 23, 2017. The Journal of Clinical Oncology had the largest number of publications, the USA was the leading country, and the University of Texas MD Anderson Cancer Center was the leading institution. Ajani JA published the most papers, and Jemal A had the highest co-citation counts. Esophageal squamous cell carcinoma ranked the first in research hotspots, and preoperative chemotherapy/chemoradiotherapy ranked the first in research frontiers.


CONCLUSION
The annual number of publications steadily increased in the past decade. A considerable number of papers were published in journals with high impact factor. Many Chinese institutions engaged in esophageal and EGJ cancer research but significant collaborations among them were not noted. Jemal A, Van Hagen P, Cunningham D, and Enzinger PC were identified as good candidates for research collaboration. Neoadjuvant therapy and genome-wide association study in esophageal and EGJ cancer research should be closely observed.
Maximin Action Identification: A New Bandit Framework for Games

We study an original problem of pure exploration in a strategic bandit model motivated by Monte Carlo Tree Search. It consists in identifying the best action in a game, when the player may sample random outcomes of sequentially chosen pairs of actions. We propose two strategies for the fixed-confidence setting: Maximin-LUCB, based on lowerand upperconfidence bounds; and Maximin-Racing, which operates by successively eliminating the sub-optimal actions. We discuss the sample complexity of both methods and compare their performance empirically. We sketch a lower bound analysis, and possible connections to an optimal algorithm.
Perceptual cryptography on MPEG-1 layer III bit-streams

Whereas conventional cryptography is suitable for any kind of data, it does not allow for perceptual degradation of encrypted data in multimedia-compressed formats. In this article we present perceptual cryptography applied to MPEG Layer III compressed audio (MP3). The inputs of the cipher are the plaintext MP3 bit-stream, encryption key and encryption percentage. The cipher outputs a MPEG Layer III compliant bit-stream (ciphertext) that is perceptually less valuable than the original bit-stream. The original MP3 bit-stream can be recovered using the ciphertext bit-stream and the same decryption key and percentage used on encryption. An introduction to MP3 audio compression is given followed by a description of the perceptual cipher. The paper addresses the relationship between the encryption percentage and the subjective quality.
Metal–Organic Framework Thin Films Composed of Free-Standing Acicular Nanorods Exhibiting Reversible Electrochromism

A uniform and crack-free metal−organic framework (MOF) thin film composed of free-standing acicular nanorods was grown on a transparent conducting glass substrate. The MOF thin film exhibits electrochromic switching between yellow and deep blue by means of a one-electron redox reaction at its pyrene-based linkers. The rigid MOF stabilizes the radical cations of the pyrene linkers at positive applied potential, resulting in the reversible color change of the MOF film. The regular and uniform channels of the MOF allow ions to migrate through the entire film. The MOF thin film thus exhibits a remarkable color change and rapid switching rate.
Associations between physical activity , sedentary behavior , and glycemic control in a large cohort of adolescents with type 1 diabetes : the Hvidoere Study Group on Childhood Diabetes

Background: The Hvidoere Study Group on Childhood Diabetes has demonstrated persistent differences in metabolic outcomes between pediatric diabetes centers. These differences cannot be accounted for by differences in demographic, medical, or treatment variables. Therefore, we sought to explore whether differences in physical activity or sedentary behavior could explain the variation in metabolic outcomes between centers. Methods: An observational cross-sectional international study in 21 centers, with demographic and clinical data obtained by questionnaire from participants. Hemoglobin A1c (HbA1c) levels were assayed in one central laboratory. All individuals with diabetes aged 11–18 yr (49.4% female), with duration of diabetes of at least 1 yr, were invited to participate. Individuals completed a self-reported measure of quality of life (Diabetes Quality of Life Short Form [DQOL-SF]), with well-being and leisure time activity assessed using measures developed by Health Behaviour in School Children WHO Project. Results: Older participants (p , 0.001) and females (p , 0.001) reported less physical activity. Physical activity was associated with positive health perception (p , 0.001) but not with glycemic control, body mass index, frequency of hypoglycemia, or diabetic ketoacidosis. The more time spent on the computer (r 1⁄4 0.06; p , 0.05) and less time spent doing school homework (r 1⁄4 20.09; p , 0.001) were associated with higher HbA1c. Between centers, there were significant differences in reported physical activity (p , 0.001) and sedentary behavior (p , 0.001), but these differences did not account for center differences in metabolic control. Conclusions: Physical activity is strongly associated with psychological well-being but has weak associations with metabolic control. Leisure time activity is associated with individual differences in HbA1c but not with intercenter differences. J Åman, TC Skinner, CE de Beaufort, PGF Swift, H-J Aanstoot and F Cameron, for and on behalf of Hvidoere Study Group on Childhood Diabetes Department of Paediatrics, Örebro University Hospital, Örebro, Sweden; Department of Psychology, University of Wollongong, Wollongong, Australia; Clinique Pédiatrique, Centre Hospitalier de Luxembourg, Luxembourg, Luxembourg; Children’s Hospital, Leicester Royal Infirmary, Leicester, UK; Diabetes Center for Pediatric and Adolescent Diabetes, Rotterdam, The Netherlands; and Department of Endocrinology and Diabetes, Royal Children’s Hospital, Parkville, Victoria, Australia
Cutaneous sarcoidosis.

Sarcoidosis is a systemic disease with skin manifestations. Skin manifestations are classified as nonspecific if they are not characterized by granulomatous inflammation and specific if the lesions have granulomas histologically. Erythema nodosum is the most common nonspecific skin manifestation, and it portends a good prognosis. Specific skin lesions have a varied clinical appearance, although often they can be distinguished by their yellow translucent character. Despite the potential variable appearance, there are common clinical presentations. Lupus pernio lesions are nodular violaceous specific skin lesions found predominantly on the face associated with scarring and a poor prognosis. Treatment of cutaneous sarcoidosis is primarily done to avoid scarring and cosmetic disfigurement. Local and systemic corticosteroids are the mainstay of treatment for the disease. Corticosteroid-sparing agents used to manage the disease include antimalarials, methotrexate, and tetracycline antibiotics. Tumor necrosis factor-alpha (TNF-alpha) antagonists such as infliximab may have a role in cutaneous sarcoidosis, especially in refractory cases that are resistant to the standard regimens.
Evolution and origin of sympatric shallow-water morphotypes of Lake Trout, Salvelinus namaycush, in Canada’s Great Bear Lake

Range expansion in north-temperate fishes subsequent to the retreat of the Wisconsinan glaciers has resulted in the rapid colonization of previously unexploited, heterogeneous habitats and, in many situations, secondary contact among conspecific lineages that were once previously isolated. Such ecological opportunity coupled with reduced competition likely promoted morphological and genetic differentiation within and among post-glacial fish populations. Discrete morphological forms existing in sympatry, for example, have now been described in many species, yet few studies have directly assessed the association between morphological and genetic variation. Morphotypes of Lake Trout, Salvelinus namaycush, are found in several large-lake systems including Great Bear Lake (GBL), Northwest Territories, Canada, where several shallow-water forms are known. Here, we assess microsatellite and mitochondrial DNA variation among four morphotypes of Lake Trout from the five distinct arms of GBL, and also from locations outside of this system to evaluate several hypotheses concerning the evolution of morphological variation in this species. Our data indicate that morphotypes of Lake Trout from GBL are genetically differentiated from one another, yet the morphotypes are still genetically more similar to one another compared with populations from outside of this system. Furthermore, our data suggest that Lake Trout colonized GBL following dispersal from a single glacial refugium (the Mississippian) and support an intra-lake model of divergence. Overall, our study provides insights into the origins of morphological and genetic variation in post-glacial populations of fishes and provides benchmarks important for monitoring Lake Trout biodiversity in a region thought to be disproportionately susceptible to impacts from climate change.
Food waste within global food systems - September 2013

(2013) Food waste within global food systems. A Global Food Security report (www.foodsecurity.ac.uk).
Exploring the Meaning of Freedom: Postemancipation Societies in Comparative Perspective

HE centennial of the final abolition of slavery in Cuba and Brazil has occasioned an exceptional burst of scholarly interest, perhaps in part owinig to the moral weight that the questions of slavery and freedom continue to carry.' Integrating a moral vision into scholarship on this subject, however, has remained problematic. The old notion of slave emancipation as a purifying, redemptive triumph of moral rightness over self-interest has receded, sometimes to be replaced by a more jaundiced view of emancipation as the trading of one master for another, or the relinquishing of explicit coercion and explicit protection for implicit coercion and no protection at all. The best recent work on emancipation has challenged these polarities, emphasizing the complexity of former slaves' initiatives in the context of the constraints placed on them.2
Doppler Ultrasound of Hepatic Blood Flow for Noninvasive Evaluation of Liver Fibrosis Compared with Liver Biopsy and Transient Elastography

Accurate quantification of liver fibrosis is essential for therapeutic decision-making and follow-up of chronic liver diseases. To optimize the quality of non-invasive assessment of liver fibrosis in patients with chronic hepatopathy we compared Doppler ultrasound with liver histology and transient elastography (TE). In this prospective observational study, we performed Doppler ultrasound of hepatic blood vessels as well as TE in 125 patients who underwent liver biopsy for diagnostic work-up of hepatopathy. Hepatic venous flow was evaluated by determining resistance index (HVRI) of the right hepatic vein. Doppler and TE results were compared with histological staging, grading and degree of steatosis obtained by liver biopsy. HVRI showed a high reliability in predicting fibrosis stage FII or higher (AUROC 93.7 %, HVRI < 1.185; sensitivity 89.66 % and specificity 86.32 %) and was superior to TE. Neither steatosis nor inflammation had significant influence on HVRI-based estimation of fibrosis (1.45 ± 0.2; 1.26 ± 0.05; 1.06 ± 0.06; 0.87 ± 0.08; 0.46 ± 0.11 for F0–FIV, respectively). HVRI differed significantly in different stages of fibrosis. In contrast, portal vein and hepatic artery only showed significant changes in higher stages of fibrosis. Hepatic artery resistance index was elevated (0.67–0.74; p < 0.05); portal vein flow maximum and undulation were significantly reduced in higher fibrosis (p < 0.05 and p < 0.01, respectively). Hepatic blood flow analysis, especially HVRI, provides useful information during assessment of hepatopathy and is a reliable predictor of liver fibrosis stage FII or higher as part of the non-invasive diagnostic work-up and follow-up in chronic liver disease.
Micro aerial vehicle type wall-climbing robot mechanism

Nowadays, as the building structures are getting taller and taller, the importance of maintenance or inspection of these structures is being increased. However, it has some problems due to the lack of professional manpower and there is a risk in maintaining those areas that are hard to reach, besides the high maintenance cost. The unmanned wall-climbing robots for the areas hard to reach have been researched to solve the problems. The infrastructure-based wall-climbing robots have high payload and safety but the robots need the infrastructure that should be installed on the target structure. The infrastructure is not preferred by the architects since it can be harmful to the exterior of the structure. For this reason, wall-climbing robots that do not need any infrastructure are being researched. Nevertheless, most of the non-infrastructure-based wall-climbing robots are in the laboratory level since the payload, safety and maneuverability are not satisfactory. To overcome these problems, a flight-possible wall-climbing robot mechanism is proposed in this paper. The robot is based on the quadrotor system that is a well-known aerial vehicle using four rotors. It uses thrust forces induced by the four rotors not only to fly but also to stick on the wall. The flight capability makes its maneuverability and safety greatly enhanced. The feasibility of the mechanism is shown through simulations and experiments with a prototype.
Awareness of Menstrual Abnormality Amongst College Students in Urban Area of Ile-Ife, Osun State, Nigeria

BACKGROUND
Disturbances of menstrual bleeding are major social and medical problem for women and account for high percentage of gynecological visit.


OBJECTIVES
The objective of the study was to document menstrual abnormalities experienced by female college students, their awareness and health seeking behavior.


MATERIALS AND METHODS
A cross-sectional survey was undertaken, 400 students were selected using stratified sampling technique and interviewed using semi-structured self-administered questionnaire. Inferential statistical analysis such as Chi-square test and logistic regressions were carried out.


RESULTS
The mean age at menarche was 14.18 years. Irregular menstrual cycles were reported in 9.0%. Dysmenorrhea was present in 62.5%, and 12.5% reported school absenteeism. Students' awareness of menstrual abnormalities was poor (29%). A few of them (10.5%) decided to seek help for menstrual abnormalities. The awareness of students on menstrual abnormalities was significantly influenced by their age (OR = 2.33, P = 0.03); however, age at menarche and level of study did not influence their awareness (OR = 0.45, P = 0.24 and OR = 1.42, P = 0.12). History of dysmenorrheal (OR = 10.2, P = 0.001) and academic disturbance (OR = 5.45, P = 0.001) had significant influence on the health seeking behavior of the students.


CONCLUSION
There was a general lack of information about menstrual issues and when to seek help. There is a need to educate female college students about menstrual issues in order to improve their health seeking behavior as regards menstrual abnormalities.
A High Performance Configurable Storage Manager

This paper presents the architecture of BeSS ~ a high performance configurable database storage manager providing key facilities for the fast development of object-oriented, relational, or home-grown database management systems. BeSS is based on a multi-client multi-server architecture offering distributed transaction management facilities and extensible support for persistence. W e present some novel aspects of the BeSS architecture, including a fast object reference technique that allows re-organization of databases without affecting existing references and two operation modes an application running on a client or server machine can use to interact with the storage system copy on access and shared memory.
Using mathematical morphology for document skew estimation

We propose a concise definition of the skew angle of document, based on mathematical morphology. This definition has the advantages to be applicable both for binary and grey-scale images. We then discuss various possible implementations of this definition, and show that results we obtain are comparable to those of other existing algorithms.
Circumferential pulmonary vein isolation with the cryoballoon technique results from a prospective 3-center study.

OBJECTIVES
The purpose of this study was to investigate the efficacy safety of the novel cryoballoon device (Arctic Front, Cryocath, Quebec, Canada).


BACKGROUND
Antral pulmonary vein (PV) ablation with radiofrequency energy is widely used as a strategy for catheter ablation of paroxysmal atrial fibrillation (PAF). A novel double lumen cryoballoon catheter was designed for circumferential pulmonary vein isolation (PVI) with the cryoablation technique.


METHODS
We consecutively enrolled 346 patients with symptomatic, drug refractory paroxysmal (n = 293) or persistent (n = 53) atrial fibrillation (AF). In all patients, PVI of all targeted PVs was the therapeutic aim. The primary end points of this nonrandomized study were: 1) acute isolation rate of targeted PV; and 2) first electrocardiogram-documented recurrence of AF. The secondary end point was occurrence of PV stenosis or atrio-esophageal fistula.


RESULTS
The 1,360 of 1,403 PVs (97%) were targeted with balloons or balloons in combination with the use of Freezor Max (Cryocath). We found that ablation with the cryoballoon resulted in maintenance of sinus rhythm in 74% of patients with PAF and 42% of patients with persistent AF. No PV narrowing occurred. The most frequent complication was right phrenic nerve palsy observed during cryoballoon ablation at the right superior PV.


CONCLUSIONS
Pulmonary vein isolation with a new cryoballoon technique is feasible. Sinus rhythm can be maintained in the majority of patients with PAF by circumferential PVI using a cryoballoon ablation system. Cryoablation was less effective in patients with persistent AF than in patients with PAF.
Abstraction for Solving Large Incomplete-Information Games

ion for Solving Large Incomplete-Information Games Tuomas Sandholm Computer Science Department Carnegie Mellon University
Inventive progress measured by multI-stage patent citation analysis

Studies of technological change constitute a field of growing importance and sophistication. In this paper we contribute to the discussion with a methodological reflection and application of multi-stage patent citation analysis for the mea surement of inventive progress. Investigating specific patterns of patent citation data, we conclude that single-stage citation analysis cannot reveal technological paths or linea ges. Therefore, one should also make use of indirect citations and bibliographical coupling. To measure aspects of cumulative inventive progress, we develop a “shared specialization measu r ” of patent families. We relate this measure to an expert rating of the technological va lue dded in the field of variable valve actuation for internal combustion engines. In sum, the study presents promising evidence for multi-stage patent citation analysis in order to ex plain aspects of technological change. JEL classification: O31
Tools and Techniques for Event Log Analysis

................................................................................. 4 KOKKUVÕTE............................................................................... 5 ACKNOWLEDGEMENTS ............................................................ 6 PART I OVERVIEW.................................................................... 7
A Survey of Automated Web Service Composition Methods

In today’s Web, Web services are created and updated on the fly. It’s already beyond the human ability to analysis them and generate the composition plan manually. A number of approaches have been proposed to tackle that problem. Most of them are inspired by the researches in cross-enterprise workflow and AI planning. This paper gives an overview of recent research efforts of automatic Web service composition both from the workflow and AI planning research community.
An Ethical Governor for Constraining Lethal Action in an Autonomous System

The design, prototype implementation, and demonstration of an ethical governor capable of restricting lethal action of an autonomous system in a manner consistent with the Laws of War and Rules of Engagement is presented.
An architecture for aggregating information from distributed data nodes for industrial internet of things

The current Internet of Things (IoT) has made it very convenient to obtain information about a product from a single data node. However, in many industrial applications, information about a single product can be distributed in multiple different data nodes, and aggregating the information from these nodes has become a common task. In this paper, we provide a distributed service-oriented architecture for this task. In this architecture, each manufacturer provides service for their own products, and data nodes keep the information collected by themselves. Semantic technologies are adopted to handle problems of heterogeneity and serve as the foundation to support different applications. Finally, as an example, we illustrate the use of this architecture to solve the problem of product tracing. © 2016 Elsevier Ltd. All rights reserved.
Epidermal growth factor receptor expression escapes androgen regulation in prostate cancer: a potential molecular switch for tumour growth

Androgen deprivation therapy reduces prostate cancer (PCa) tumour growth; however, disease relapse often ensues independently of androgen stimulation, producing androgen-refractory tumours with increased invasion, proliferation, and malignancy. Androgens downregulate epidermal growth factor receptor (EGFR) in normal prostate but not in PCa. Thus, loss of EGFR regulation and altered signalling may, in part, explain the transition of prostate tumours from androgen dependent to androgen independent. Studies in animal models, PCa cell lines, and tumour specimens suggest that androgens modulate prostate growth and function through mechanisms that involve ‘cross-talk’ between androgen receptor (AR) and growth factor receptor signalling pathways. The objective of this review is to discuss the paradoxical relationship between androgen regulation of EGFR in normal prostate and PCa. We reviewed the literature from mid-1980s through 2009 to assess the relationship between androgens and EGFR function in modulating the growth of normal prostate and PCa. Loss of androgen regulation of EGFR in PCa may be responsible for increased tumour growth, invasion, and metastasis, with important implications on the clinical management of PCa. We advance the hypothesis that a molecular switch, responsible for downregulating EGFR expression by androgens in the normal prostate, is either lost or modified in PCa.