LLukas22/scidocs huggingface dataset:
Development and validation of a cancer awareness questionnaire for Malaysian undergraduate students of Chinese ethnicity.

OBJECTIVES
To describe the development and validation of a cancer awareness questionnaire (CAQ) based on a literature review of previous studies, focusing on cancer awareness and prevention.


MATERIALS AND METHODS
A total of 388 Chinese undergraduate students in a private university in Kuala Lumpur, Malaysia, were recruited to evaluate the developed self-administered questionnaire. The CAQ consisted of four sections: awareness of cancer warning signs and screening tests; knowledge of cancer risk factors; barriers in seeking medical advice; and attitudes towards cancer and cancer prevention. The questionnaire was evaluated for construct validity using principal component analysis and internal consistency using Cronbach's alpha (α) coefficient. Test-retest reliability was assessed with a 10-14 days interval and measured using Pearson product-moment correlation.


RESULTS
The initial 77-item CAQ was reduced to 63 items, with satisfactory construct validity, and a high total internal consistency (Cronbach's α=0.77). A total of 143 students completed the questionnaire for the test-retest reliability obtaining a correlation of 0.72 (p<0.001) overall.


CONCLUSIONS
The CAQ could provide a reliable and valid measure that can be used to assess cancer awareness among local Chinese undergraduate students. However, further studies among students from different backgrounds (e.g. ethnicity) are required in order to facilitate the use of the cancer awareness questionnaire among all university students.
Achieving concentrated graphene dispersions in water/acetone mixtures by the strategy of tailoring Hansen solubility parameters

Although exfoliating graphite to give graphene paves a new way for graphene preparation, a general strategy of low-boiling-point solvents and high graphene concentration is still highly required. In this study, using the strategy of tailoring Hansen solubility parameters (HSP), a method based on exfoliation of graphite in water/acetone mixtures is demonstrated to achieve concentrated graphene dispersions. It is found that in the scope of blending two mediocre solvents, tailoring the HSP of water/acetone mixtures to approach the HSP of graphene could yield graphene dispersions at a high concentration of up to 0.21 mg ml−1. The experimentally determined optimum composition of the mixtures occurs at an acetone mass fraction of ∼75%. The trend of concentration varying with mixture compositions could be well predicated by the model, which relates the concentration to the mixing enthalpy within the scope of HSP theory. The resultant dispersion is highly stabilized. Atomic force microscopic statistical analysis shows that up to ∼50% of the prepared nanosheets are less than 1 nm thick after 4 h sonication and 114g centrifugation. Analyses based on diverse characterizations indicate the graphene sheets to be largely free of basal plane defects and oxidation. The filtered films are also investigated in terms of their electrical and optical properties to show reasonable conductivity and transparency. The strategy of tailoring HSP, which can be easily extended to various solvent systems, and water/acetone mixtures here, extends the scope for large-scale production of graphene in low-boiling-point solutions. (Some figures may appear in colour only in the online journal)
Effects of adenosine on human coronary arterial circulation.

Adenosine is a potent vasodilator used extensively to study the coronary circulation of animals. Its use in humans, however, has been hampered by lack of knowledge about its effects on the human coronary circulation and by concern about its safety. We investigated in humans the effects of adenosine, administered by intracoronary bolus (2-16 micrograms), intracoronary infusion (10-240 micrograms/min), or intravenous infusion (35-140 micrograms/kg/min) on coronary and systemic hemodynamics and the electrocardiogram. Coronary blood flow velocity (CBFV) was measured with a 3F coronary Doppler catheter. The maximal CBFV was determined with intracoronary papaverine (4.5 +/- 0.2.resting CBFV). In normal left coronary arteries (n = 20), 16-micrograms boluses of adenosine caused coronary hyperemia similar to that caused by papaverine (4.6 +/- 0.7.resting CBFV). In the right coronary artery (n = 5), 12-micrograms boluses caused maximal hyperemia (4.4 +/- 1.0.resting CBFV). Intracoronary boluses caused a small, brief decrease in arterial pressure (similar to that caused by papaverine) and no changes in heart rate or in the electrocardiogram. The duration of hyperemia was much shorter after adenosine than after papaverine administration. Intracoronary infusions of 80 micrograms/min or more into the left coronary artery (n = 6) also caused maximal hyperemia (4.4 +/- 0.1.resting CBFV), and doses up to 240 micrograms/min caused a minimal decrease in arterial pressure (-6 +/- 2 mm Hg) and no significant change in heart rate or in electrocardiographic variables. Intravenous infusions in normal patients (n = 25) at 140 micrograms/kg/min caused coronary vasodilation similar to that caused by papaverine in 84% of patients (4.4 +/- 0.9.resting CBFV). At submaximal infusion rates, however, CBFV often fluctuated widely. During the 140-micrograms/kg/min infusion, arterial pressure decreased 6 +/- 7 mm Hg, and heart rate increased 24 +/- 14 beats/min. One patient developed 1 cycle of 2:1 atrioventricular block, but otherwise, the electrocardiogram did not change. In eight patients with microvascular vasodilator dysfunction (delta CBFV, less than 3.5 peak/resting velocity after a maximally vasodilating dose of intracoronary papaverine), the dose-response characteristics to intracoronary boluses and intravenous infusions of adenosine were similar to those found in normal patients.(ABSTRACT TRUNCATED AT 400 WORDS)
A Survey of Text Classification Algorithms

The problem of classification has been widely studied in the data mining, machine learning, database, and information retrieval communities with applications in a number of diverse domains, such as target marketing, medical diagnosis, news group filtering, and document organization. In this paper we will provide a survey of a wide variety of text classification
Towards noncommutative gravity

In this short article accessible for non-experts I discuss possible ways of constructing a non-commutative gravity paying special attention to possibilities of realizing the full diffeomorphism symmetry and to relations with 2D gravities.
Chemically Aware Model Builder (camb): an R package for property and bioactivity modelling of small molecules

BACKGROUND
In silico predictive models have proved to be valuable for the optimisation of compound potency, selectivity and safety profiles in the drug discovery process.


RESULTS
camb is an R package that provides an environment for the rapid generation of quantitative Structure-Property and Structure-Activity models for small molecules (including QSAR, QSPR, QSAM, PCM) and is aimed at both advanced and beginner R users. camb's capabilities include the standardisation of chemical structure representation, computation of 905 one-dimensional and 14 fingerprint type descriptors for small molecules, 8 types of amino acid descriptors, 13 whole protein sequence descriptors, filtering methods for feature selection, generation of predictive models (using an interface to the R package caret), as well as techniques to create model ensembles using techniques from the R package caretEnsemble). Results can be visualised through high-quality, customisable plots (R package ggplot2).


CONCLUSIONS
Overall, camb constitutes an open-source framework to perform the following steps: (1) compound standardisation, (2) molecular and protein descriptor calculation, (3) descriptor pre-processing and model training, visualisation and validation, and (4) bioactivity/property prediction for new molecules. camb aims to speed model generation, in order to provide reproducibility and tests of robustness. QSPR and proteochemometric case studies are included which demonstrate camb's application.Graphical abstractFrom compounds and data to models: a complete model building workflow in one package.
QCD Constraints on Form Factor Shapes

This talk presents an introduction to the use of dispersion relations to constrain the shapes of hadronic form factors consistent with QCD. The applications described include methods for studying |V_{cb}| and |V_{ub}|, the strange quark mass, and the pion charge radius.
RemoTouch: A system for remote touch experience

This paper presents some preliminary results on RemoTouch, a system allowing to perform experiences of remote touch. The system consists of an avatar equipped with an instrumented glove and a user wearing tactile displays allowing to feel the remote tactile interaction. The main features of RemoTouch are that it is a wearable system and that a human avatar is used to collect remote tactile interaction data. New paradigms of tactile communication can be designed around the RemoTouch system. Two simple experiences are reported to show the potential of the proposed remote touch architecture.
A new visual search interface for web browsing

We introduce a new visual search interface for search engines. The interface is a user-friendly and informative graphical front-end for organizing and presenting search results in the form of topic groups. Such a semantics-oriented search result presentation is in contrast with conventional search interfaces which present search results according to the physical structures of the information. Given a user query, our interface first retrieves relevant online materials via a third-party search engine. And then we analyze the semantics of search results to detect latent topics in the result set. Once the topics are detected, we map the search result pages into topic clusters. According to the topic clustering result, we divide the available screen space for our visual interface into multiple topic displaying regions, one for each topic. For each topic's displaying region, we summarize the information contained in the search results under the corresponding topic so that only key messages will be displayed. With this new visual search interface, users are conveyed the key information in the search results expediently. With the key information, users can navigate to the final, desired results with less effort and time than conventional searching. Supplementary materials for this paper are available at http://www.cs.hku.hk/~songhua/visualsearch/.
Precision Dairy Farming: Advanced Analysis Solutions for Future Profitability

Precision Dairy Farming is the use of technologies to measure physiological, behavioral, and production indicators on individual animals to improve management strategies and farm performance. Many Precision Dairy Farming technologies, including daily milk yield recording, milk component monitoring, pedometers, automatic temperature recording devices, milk conductivity indicators, automatic estrus detection monitors, and daily body weight measurements, are already being utilized by dairy producers. Other theoretical Precision Dairy Farming technologies have been proposed to measure jaw movements, ruminal pH, reticular contractions, heart rate, animal positioning and activity, vaginal mucus electrical resistance, feeding behavior, lying behavior, odor, glucose, acoustics, progesterone, individual milk components, color (as an indicator of cleanliness), infrared udder surface temperatures, and respiration rates. The main objectives of Precision Dairy Farming are maximizing individual animal potential, early detection of disease, and minimizing the use of medication through preventive health measures. Perceived benefits of Precision Dairy Farming technologies include increased efficiency, reduced costs, improved product quality, minimized adverse environmental impacts, and improved animal health and well-being. Real time data used for monitoring animals may be incorporated into decision support systems designed to facilitate decision making for issues that require compilation of multiple sources of data. Technologies for physiological monitoring of dairy cows have great potential to supplement the observational activities of skilled herdspersons, which is especially critical as more cows are managed by fewer skilled workers. Moreover, data provided by these technologies may be incorporated into genetic evaluations for non-production traits aimed at improving animal health, well-being, and longevity. The economic implications of technology adoption must be explored further to increase adoption rates of Precision Dairy Farming technologies. Precision Dairy Farming may prove to be the next important technological breakthrough for the dairy industry.
Development of piezoelectric micromachined ultrasonic transducers

Piezoelectric micromachined ultrasonic transducers (pMUTs) are an example of the application of MEMS technology to ultrasound generation and detection, which is expected to offer many advantages over conventional transducers. In this work, we investigate pMUTs through novel design and fabrication methods. A finite element (FE) model, with original tools to measure device performance, was developed to design and optimize pMUTs. A pMUT for the operating range of 2–10 MHz in water and having maximized energy coupling coefficient was modeled, designed, fabricated, and tested for its resonance frequency and coupling coefficient. The model predictions for the resonance frequency were in excellent agreement with the measured values, but not as good for the coupling coefficient due to the variability in the measured coupling coefficient. Compared to conventional ultrasonic transducers, pMUTs exhibit superior bandwidth, in excess of 100%, and offer considerable design flexibility, which allows their operation frequency and acoustic impedance to be tailored for numerous applications. © 2003 Elsevier B.V. All rights reserved.
Deep 3D face identification

We propose a novel 3D face recognition algorithm using a deep convolutional neural network (DCNN) and a 3D face expression augmentation technique. The performance of 2D face recognition algorithms has significantly increased by leveraging the representational power of deep neural networks and the use of large-scale labeled training data. In this paper, we show that transfer learning from a CNN trained on 2D face images can effectively work for 3D face recognition by fine-tuning the CNN with an extremely small number of 3D facial scans. We also propose a 3D face expression augmentation technique which synthesizes a number of different facial expressions from a single 3D face scan. Our proposed method shows excellent recognition results on Bosphorus, BU-3DFE, and 3D-TEC datasets without using hand-crafted features. The 3D face identification using our deep features also scales well for large databases.
Early effects of raloxifene on clinical vertebral fractures at 12 months in postmenopausal women with osteoporosis.

BACKGROUND
Raloxifene hydrochloride therapy reduces the risk for vertebral fractures at 3 years, but the effects on clinical vertebral fractures in the first year are not known.


METHODS
The Multiple Outcomes of Raloxifene Evaluation (MORE) Trial enrolled 7705 women with osteoporosis, defined by prevalent vertebral fractures and/or a bone mineral density (BMD) T score at or below -2.5, who were treated with placebo or raloxifene at a dosage of 60 or 120 mg/d for 3 years. New clinical vertebral fractures were defined as incident vertebral fractures associated with signs and symptoms suggestive of vertebral fractures, such as back pain, and were diagnosed by means of postbaseline adjudicated spinal radiographs. Scheduled spinal radiographs were obtained at baseline and at 2 and 3 years. In addition, unscheduled spinal radiographs were obtained in women who reported signs or symptoms suggestive of vertebral fracture, and these radiographs subsequently underwent adjudication. If an adjudicated fracture was identified, this was also considered a clinical fracture.


RESULTS
At 1 year, raloxifene, 60 mg/d, decreased the risk for new clinical vertebral fractures by 68% (95% confidence interval [CI], 20%-87%) compared with placebo in the overall study population, and by 66% (95% CI, 23%-89%) in women with prevalent vertebral fractures, who are at greater risk for subsequent fracture. The risk for clinical vertebral fractures in the raloxifene, 60 mg/d, group was decreased by 46% (95% CI, 14%-66%) at 2 years and by 41% (95% CI, 17%-59%) at 3 years. The cumulative incidence of new clinical vertebral fractures was lower in the group receiving raloxifene, 60 mg/d, compared with placebo (P<.001). We found no significant differences in the risk reductions for clinical vertebral fractures between the raloxifene groups at 1, 2, or 3 years.


CONCLUSION
The early risk reduction for new clinical vertebral fractures with 1 year of raloxifene treatment was similar to that reported with other antiresorptive agents.
The effect of a pre- and postoperative orthogeriatric service on cognitive function in patients with hip fracture: randomized controlled trial (Oslo Orthogeriatric Trial)

BACKGROUND
Delirium is a common complication in patients with hip fractures and is associated with an increased risk of subsequent dementia. The aim of this trial was to evaluate the effect of a pre- and postoperative orthogeriatric service on the prevention of delirium and longer-term cognitive decline.


METHODS
This was a single-center, prospective, randomized controlled trial in which patients with hip fracture were randomized to treatment in an acute geriatric ward or standard orthopedic ward. Inclusion and randomization took place in the Emergency Department at Oslo University hospital. The key intervention in the acute geriatric ward was Comprehensive Geriatric Assessment including daily interdisciplinary meetings. Primary outcome was cognitive function four months after surgery measured using a composite outcome incorporating the Clinical Dementia Rating Scale (CDR) and the 10 words learning and recalls tasks from the Consortium to Establish a Registry for Alzheimer's Disease battery (CERAD). Secondary outcomes were pre- and postoperative delirium, delirium severity and duration, mortality and mobility (measured by the Short Physical Performance Battery (SPPB)). Patients were assessed four and twelve months after surgery by evaluators blind to allocation.


RESULTS
A total of 329 patients were included. There was no significant difference in cognitive function four months after surgery between patients treated in the acute geriatric and the orthopedic wards (mean 54.7 versus 52.9, 95% confidence interval for the difference -5.9 to 9.5; P = 0.65). There was also no significant difference in delirium rates (49% versus 53%, P = 0.51) or four month mortality (17% versus 15%, P = 0.50) between the intervention and the control group. In a pre-planned sub-group analysis, participants living in their own home at baseline who were randomized to orthogeriatric care had better mobility four months after surgery compared with patients randomized to the orthopedic ward, measured with SPPB (median 6 versus 4, 95% confidence interval for the median difference 0 to 2; P = 0.04).


CONCLUSIONS
Pre- and postoperative orthogeriatric care given in an acute geriatric ward was not effective in reducing delirium or long-term cognitive impairment in patients with hip fracture. The intervention had, however, a positive effect on mobility in patients not admitted from nursing homes.


TRIAL REGISTRATION
ClinicalTrials.gov NCT01009268 Registered November 5, 2009.
Silver sulfadiazine loaded chitosan/chondroitin sulfate films for a potential wound dressing application.

Silver sulfadiazine (AgSD) loaded chitosan/chondroitin sulfate (CHI/CS) films were formed to be applied as a potential wound dressing material. The liquid uptake capacity of both, CHI/CS and CHI/CS/AgSD, films exhibited a pH-dependent behavior. Tensile tests showed that the amount of CS used to form the films and the further incorporation of AgSD affect the mechanical properties of the films. In vitro AgSD-release assays showed that the CHI/CS mass ratio influences the AgSD release rate. All the investigated CHI/CS/AgSD films sustain the AgSD release up to 96h at physiological pH. Antibacterial activity and cell viability assays showed that all the CHI/CS/AgSD films have activity against Pseudomonas aeruginosa and Staphylococcus aureus but they were not toxic to Vero cells. The results presented in this work indicate that the CHI/CS/AgSD exhibits potential to be applied as a wound dressing material.
Semantic representation of scientific literature: bringing claims, contributions and named entities onto the Linked Open Data cloud

Title Semantic representation of scientific literature: bringing claims, contributions and named entities onto the Linked Open Data cloud Publication Type Journal Article Year of Publication 2015 Authors Sateli, B. [13], and R. Witte [14] Refereed Designation Refereed Editors Sumner, T. [15] Journal PeerJ Computer Science Volume 1 Issue e37 Date Published 12/2015
A randomized clinical trial of eye movement desensitization and reprocessing (EMDR), fluoxetine, and pill placebo in the treatment of posttraumatic stress disorder: treatment effects and long-term maintenance.

OBJECTIVE
The relative short-term efficacy and long-term benefits of pharmacologic versus psychotherapeutic interventions have not been studied for posttraumatic stress disorder (PTSD). This study compared the efficacy of a selective serotonin reup-take inhibitor (SSRI), fluoxetine, with a psychotherapeutic treatment, eye movement desensitization and reprocessing (EMDR), and pill placebo and measured maintenance of treatment gains at 6-month follow-up.


METHOD
Eighty-eight PTSD subjects diagnosed according to DSM-IV criteria were randomly assigned to EMDR, fluoxetine, or pill placebo. They received 8 weeks of treatment and were assessed by blind raters posttreatment and at 6-month follow-up. The primary outcome measure was the Clinician-Administered PTSD Scale, DSM-IV version, and the secondary outcome measure was the Beck Depression Inventory-II. The study ran from July 2000 through July 2003.


RESULTS
The psychotherapy intervention was more successful than pharmacotherapy in achieving sustained reductions in PTSD and depression symptoms, but this benefit accrued primarily for adult-onset trauma survivors. At 6-month follow-up, 75.0% of adult-onset versus 33.3% of child-onset trauma subjects receiving EMDR achieved asymptomatic end-state functioning compared with none in the fluoxetine group. For most childhood-onset trauma patients, neither treatment produced complete symptom remission.


CONCLUSIONS
This study supports the efficacy of brief EMDR treatment to produce substantial and sustained reduction of PTSD and depression in most victims of adult-onset trauma. It suggests a role for SSRIs as a reliable first-line intervention to achieve moderate symptom relief for adult victims of childhood-onset trauma. Future research should assess the impact of lengthier intervention, combination treatments, and treatment sequencing on the resolution of PTSD in adults with childhood-onset trauma.