LLukas22/scidocs huggingface dataset:
Intraday periodicity and volatility persistence in financial markets

The pervasive intraday periodicity in the return volatility in foreign exchange and equity markets is shown to have a strong impact on the dynamic properties of high frequency returns. Only by taking account of this strong intraday periodicity is it possible to uncover the complex intraday volatility dynamics that exists both within and across different financial markets. The explicit periodic modeling procedure developed here provides such a framework and thus sets the stage for a formal integration of standard volatility models with market microstructure variables to allow for a more comprehensive empirical investigation of the fundamental determinants behind the volatility clustering phenomenon. © 1997 Elsevier Science B.V. JEL classification." C14; C22; GI4; G15
Neoadjuvant chemotherapy with methotrexate, cisplatin, and doxorubicin with or without ifosfamide in nonmetastatic osteosarcoma of the extremity: an Italian sarcoma group trial ISG/OS-1.

PURPOSE
We compared two chemotherapy regimens that included methotrexate (MTX), cisplatin (CDP), and doxorubicin (ADM) with or without ifosfamide (IFO) in patients with nonmetastatic osteosarcoma of the extremity.


PATIENTS AND METHODS
Patients age ≤ 40 years randomly received regimens with the same cumulative doses of drugs (ADM 420 mg/m(2), MTX 120 g/m(2), CDP 600 mg/m(2), and IFO 30 g/m(2)) but with different durations (arm A, 44 weeks; arm B, 34 weeks). IFO was given postoperatively when pathologic response to MTX-CDP-ADM was poor (arm A) or given in the primary phase of chemotherapy with MTX-CDP-ADM (arm B). End points of the study included pathologic response to preoperative chemotherapy, toxicity, and survival. Given the feasibility of accrual, the statistical plan only permitted detection of a 15% difference in 5-year overall survival (OS).


RESULTS
From April 2001 to December 2006, 246 patients were enrolled. Two hundred thirty patients (94%) underwent limb salvage surgery (arm A, 92%; arm B, 96%; P = .5). Chemotherapy-induced necrosis was good in 45% of patients (48% in arm A, 42% in arm B; P = .3). Four patients died of treatment-related toxicity (arm A, n = 1; arm B, n = 3). A significantly higher incidence of hematologic toxicity was reported in arm B. With a median follow-up of 66 months (range, 1 to 104 months), 5-year OS and event-free survival (EFS) rates were not significantly different between arm A and arm B, with OS being 73% (95% CI, 65% to 81%) in arm A and 74% (95% CI, 66% to 82%) in arm B and EFS being 64% (95% CI, 56% to 73%) in arm A and 55% (95% CI, 46% to 64%) in arm B.


CONCLUSION
IFO added to MTX, CDP, and ADM from the preoperative phase does not improve the good responder rate and increases hematologic toxicity. IFO should only be considered in patients who have a poor histologic response to MTX, CDP, and ADM.
A Smart Home Automation technique with Raspberry Pi using IoT

In this paper, we are presenting a proposed system for Smart Home Automation technique with Raspberry Pi using IoT and it is done by integrating cameras and motion sensors into a web application. To design this system, we are using a Raspberry Pi module with Computer Vision techniques. Using this, we can control home appliances connected through a monitor based internet. Raspberry Pi operates and controls motion sensors and video cameras for sensing and surveillance. For instance, it captures intruder's identity and detects its presence using simple Computer Vision Technique (CVT). Whenever motion is detected, the cameras will start recording and Raspberry Pi device alerts the owner through an SMS and alarm call.
Clinical outcomes of scaphoid and triquetral excision with capitolunate arthrodesis versus scaphoid excision and four-corner arthrodesis.

PURPOSE
To compare the clinical outcomes of scaphoid and triquetral excision combined with capitolunate arthrodesis versus 4-corner (capitate, hamate, lunate, triquetrum) intercarpal arthrodesis.


METHODS
We retrospectively identified 50 patients with scapholunate advanced collapse wrist changes who had 4-corner arthrodesis. Thirty-four patients were able to return and complete all follow-up evaluations. Patient demographics were similar between the 2 groups. Follow-up evaluation included radiographs, wrist range of motion (flexion-extension, radial-ulnar deviation, and pronation-supination); grip strength; visual analog scale (VAS); and Disabilities of the Arm, Shoulder, and Hand (DASH) questionnaire. Complications of nonunion, hardware migration, conversion to wrist arthrodesis or arthroplasty, and pisotriquetral arthritis were recorded.


RESULTS
Sixteen patients had capitolunate arthrodesis, and 18 patients had a 4-corner arthrodesis. There was no statistical difference in radial-ulnar deviation, pronation-supination, grip strength, VAS, or DASH scores between groups. There was a slight increase in flexion-extension in the 4-corner group. There were 2 nonunions in the 4-corner group and none in the capitolunate group. Five patients in the capitolunate group required screw removal secondary to migration. Three patients in the 4-corner group required a subsequent pisiform excision.


CONCLUSIONS
Capitolunate arthrodesis compares favorably to 4-corner arthrodesis at an average 3-year follow-up in this series with respect to range of motion, grip strength, DASH scores, and VAS. Advantages of capitolunate arthrodesis include a lessened need for bone graft harvesting while maintaining a similarly low nonunion rate, easier reduction of the lunate following triquetral excision, and avoiding subsequent symptomatic pisotriquetral arthritis. Screw migration, however, remains a concern with this technique.


TYPE OF STUDY/LEVEL OF EVIDENCE
Therapeutic III.
Fight sample degeneracy and impoverishment in particle filters: A review of intelligent approaches

0957-4174/$ see front matter 2013 Elsevier Ltd. All rights reserved. http://dx.doi.org/10.1016/j.eswa.2013.12.031 ⇑ Corresponding author. Tel.: +86 029 8849 4701. E-mail addresses: t.c.li@mail.nwpu.edu.cn, lit3@lsbu.ac.uk (T. Li), sdsun@ nwpu.edu.cn (S. Sun), sattartp@lsbu.ac.uk (T.P. Sattar), corchado@usal.es (J.M. Corchado). Tiancheng Li a,⇑, Shudong Sun , Tariq Pervez Sattar , Juan Manuel Corchado c
A Two-Phase Safe Vehicle Routing and Scheduling Problem: Formulations and Solution Algorithms

We propose a two phase time dependent vehicle routing and scheduling optimization model that identifies the safest routes, as a substitute for the classical objectives given in the literature such as shortest distance or travel time, through (1) avoiding recurring congestions, and (2) selecting routes that have a lower probability of crash occurrences and non-recurring congestion caused by those crashes. In the first phase, we solve a mixed-integer programming model which takes the dynamic speed variations into account on a graph of roadway networks according to the time of day, and identify the routing of a fleet and sequence of nodes on the safest feasible paths. Second phase considers each route as an independent transit path (fixed route with fixed node sequences), and tries to avoid congestion by rescheduling the departure times of each vehicle from each node, and by adjusting the sub-optimal speed on each arc. A modified simulated annealing (SA) algorithm is formulated to solve both complex models iteratively, which is found to be capable of providing solutions in a considerably short amount of time. In this paper, speed (and travel time) variation with respect to the hour of the day is calculated via queuing models (i.e., M/G/1) to capture the stochasticity of travel times more accurately unlike the most researches in this area, which assume the speed on arcs to be a fixed value or a time dependent step function. First, we demonstrate the accurate performance of M/G/1 in estimation and predicting speeds and travel times for those arcs without readily available speed data. Crash data, on the other hand, is obtained for each arc. Next, 24 scenarios, which correspond to each hour of a day, are developed, and are fed to the proposed solution algorithms. This is followed by evaluating the routing schema for each scenario where the following objective * Corresponding author. Tel.: +1-850-405-6688 E-mail address: Aschkan@ufl.edu functions are utilized: (1) the minimization of the traffic delay (maximum congestion avoidance), and (2) the minimization of the traffic crash risk, and (3) the combination of two objectives. Using these objectives, we identify the safest routes, as a substitute for the classical objectives given in the literature such as shortest distance or travel time, through (1) avoiding recurring congestions, and (2) selecting routes that have a lower probability of crash occurrences and non-recurring congestion caused by those crashes. This also allows us to discuss the feasibility and applicability of our model. Finally, the proposed methodology is applied on a benchmark network as well as a small real-world case study application for the City of Miami, Florida. Results suggest that in some instances, both the travelled distance and travel time increase in return for a safer route, however, the advantages of safer route can outweigh this slight increase.
Effect of Repetitive Transcranial Magnetic Stimulation on Patients with Brain Injury and Dysphagia

OBJECTIVE
To investigate the effect of repetitive transcranial magnetic stimulation (rTMS) on recovery of the swallowing function in patients with a brain injury.


METHOD
Patients with a brain injury and dysphagia were enrolled. Patients were randomly assigned to sham, and low and high frequency stimulation groups. We performed rTMS at 100% of motor evoked potential (MEP) threshold and a 5 Hz frequency for 10 seconds and then repeated this every minute in the high frequency group. In the low frequency group, magnetic stimulation was conducted at 100% of MEP threshold and a 1 Hz frequency. The sham group was treated using the same parameters as the high frequency group, but the coil was rotated 90° to create a stimulus noise. The treatment period was 2 weeks (5 days per week, 20 minutes per session). We evaluated the Functional Dysphagia Scale (FDS) and the Penetration Aspiration Scale (PAS) with a videofluoroscopic swallowing study before and after rTMS.


RESULTS
Thirty patients were enrolled, and mean patient age was 68.2 years. FDS and PAS scores improved significantly in the low frequency group after rTMS, and American Speech-Language Hearing Association National Outcomes Measurements System Swallowing Scale scores improved in the sham and low frequency groups. FDS and PAS scores improved significantly in the low frequency group compared to those in the other groups.


CONCLUSION
We demonstrated that low frequency rTMS facilitated the recovery of swallowing function in patients with a brain injury, suggesting that rTMS is a useful modality to recover swallowing function.
Individual differences and segment interactions in throwing

Arm segment velocities of 12 athletes throwing three differently weighted balk were analyzed by three-mode principal component analysis. Individual differences were characterized in terms of the combined influences of the phases of the throwing motion and the arm segment velocity relationships established in those phases. Using three individual differences components, three velocity measures components and four time phase components, 75% of the variance was described. The arm segment velocity relationships were described by two main components identified as directional velocity and proximal versus distal velocity. The time periods components distinguished between relationships among the m segment velocities that m u r in the windup versus those of the release phase. Three individual differences components are identified and appeared to be related to a general throwing style, the influence of skill level on technique, and the differential effect of the varying ball weights, respectively. Each athlete's throws are weighted combinations of these three components. The timing of segment involvement is investigated and the results indicate sequential patterns from proximal to distal as the throw unfolds. However, the results also suggest that different principles may apply ro different throwers and that the summation of speed principle should not be applied universally to explain segment motion and interaction.
Effects of obstructive sleep apnoea risk on postoperative respiratory complications: protocol for a hospital-based registry study

INTRODUCTION
Obstructive sleep apnoea (OSA), the most common type of sleep-disordered breathing, is associated with significant immediate and long-term morbidity, including fragmented sleep and impaired daytime functioning, as well as more severe consequences, such as hypertension, impaired cognitive function and reduced quality of life. Perioperatively, OSA occurs frequently as a consequence of pre-existing vulnerability, surgery and drug effects. The impact of OSA on postoperative respiratory complications (PRCs) needs to be better characterised. As OSA is associated with significant comorbidities, such as obesity, pulmonary hypertension, myocardial infarction and stroke, it is unclear whether OSA or its comorbidities are the mechanism of PRCs. This project aims to (1) develop a novel prediction score identifying surgical patients at high risk of OSA, (2) evaluate the association of OSA risk on PRCs and (3) evaluate if pharmacological agents used during surgery modify this association.


METHODS
Retrospective cohort study using hospital-based electronic patient data and perioperative data on medications administered and vital signs. We will use data from Partners Healthcare clinical databases, Boston, Massachusetts. First, a prediction model for OSA will be developed using OSA diagnostic codes and polysomnography procedural codes as the reference standard, and will be validated by medical record review. Results of the prediction model will be used to classify patients in the database as high, medium or low risk of OSA, and we will investigate the effect of OSA on risk of PRCs. Finally, we will test whether the effect of OSA on PRCs is modified by the use of intraoperative pharmacological agents known to increase upper airway instability, including neuromuscular blockade, neostigmine, opioids, anaesthetics and sedatives.


ETHICS AND DISSEMINATION
The Partners Human Research Committee approved this study (protocol number: 2014P000218). Study results will be made available in the form of manuscripts for publication and presentations at national and international meetings.
Study & Analysis of Web Content Mining Tools to Improve Techniques of Web Data Mining

 Abstract—Web content mining in normal parlance is to download information available on the websites. Such a process involves tremendous stress and time-taking. To augment such a process the software related to web content mining can be used so that a computer can use this software or tools to download the essential information that one would require. It collects the appropriate and perfectly fitting information from websites that one requires. In this paper several tools for web content mining are discussed and their relative merits and demerits are mentioned.
Continuous blood pressure measurement by using the pulse transit time: comparison to a cuff-based method

Pulse transit time (PTT) and pulse wave velocity (PWV), respectively, were shown to have a correlation with systolic blood pressure (SBP) and have been reported to be suitable for indirect BP measurements. The aim of this study was to create a function between SBP and PWV, and to test its reliability for the determination of absolute SBP using a non-linear algorithm and a one-point calibration. 63 volunteers performed exercise to induce rises in BP. Arterial PTT was measured between the R-spike of the ECG and the plethysmographic curve of finger pulse-oximetry. The reference BP was measured using a cuff-based sphygmomanometric aneroid device. Data from 13 of the 63 volunteers served for the detection of the PWV–BP relationship. The created non-linear function was used to calculate BP values after individual correction for the BP offset in a group of 50 volunteers. Individual correlation coefficients for SBP measured by PTT (SBPPTT) and by cuff (SBPCUFF) varied between r = 0.69 and r = 0.99. Taking all data together, we found r = 0.83 (276 measurements in 50 volunteers). In the Bland–Altman plot, the limits of agreement were $$ {\text{mean}}_{{{\text{SBP}}_{\text{PTT}} , {\text{SBP}}_{\text{CUFF}} }} $$ ± 19.8 mmHg. In conclusion, comparing SBP values using the PTT-based method and those measured by cuff resulted in a significant correlation. However, the Bland–Altman plot shows relevant differences between both methods, which are partly due to greater variability of the SBPPTT measurement during intensified exercise. Results suggest that PTT can be used for measuring absolute SBP when performing an individual correction for the offset of the BP–PWV relation.
IEEE Student Branch profile: An international blueprint

Presents a profile of the IEEE Student Branch at the National School of Engineers of Sfax (ENIS) in Tunisia.
Low Phase Noise Differential Vackar VCO in 0.18 $\mu{\rm m}$  CMOS Technology

In this letter, we present the measured performance of a differential Vackar voltage-controlled oscillator (VCO) implemented for the first time in CMOS technology. The Vackar VCO provided good isolation between the LC tank and the loss-compensating active circuit; thus, excellent frequency stability was achieved over the frequency tuning range. The Vackar VCO was implemented using nMOS transistors and an LC tank in a 0.18 μm RF CMOS process. The oscillation frequency ranged from 4.85 to 4.93 GHz. The measured phase noise of the Vackar VCO at 1 MHz offset was -124.9 dB/Hz at 4.9 GHz with a figure-of-merit (FOM) of -188 dBc/Hz.
Clustering of cases of insulin dependent diabetes (IDDM) occurring three years after hemophilus influenza B (HiB) immunization support causal relationship between immunization and IDDM.

OBJECTIVE
The hemophilus vaccine has been linked to the development of autoimmune type 1 diabetes, insulin dependent diabetes (IDDM) in ecological studies.


METHODS
We attempted to determine if the Hemophilus influenza B (HiB) vaccine was associated with an increased risk of IDDM by looking for clusters of cases of IDDM using data from a large clinical trial. All children born in Finland between October 1st, 1985 and August 31st, 1987, approximately 116,000 were randomized to receive 4 doses of the HiB vaccine (PPR-D, Connaught) starting at 3 months of life or one dose starting after 24 months of life. A control-cohort included all 128,500 children born in Finland in the 24 months prior to the HiB vaccine study. Non-obese diabetic prone (NOD) mice were immunized with a hemophilus vaccine to determine if immunization increased the risk of IDDM.


RESULTS
The difference in cumulative incidence between those receiving 4 doses and those receiving 0 doses is 54 cases of IDDM/100,000 (P = 0.026) at 7 years, (relative risk = 1.26). Most of the extra cases of IDDM appeared in statistically significant clusters that occurred in periods starting approximately 38 months after immunization and lasting approximately 6-8 months. Immunization with pediatric vaccines increased the risk of insulin diabetes in NOD mice.


CONCLUSION
Exposure to HiB immunization is associated with an increased risk of IDDM. NOD mice can be used as an animal model of vaccine induced diabetes.
Measuring the Effect of Queues on Customer Purchases

Capacity decisions in service operations often involve a trade-off between the operating cost and the service level offered to customers. Although the cost of attaining a pre-specified service level has been well-studied, there isn’t much research studying how customer service levels affect revenue and profit. This paper conducts an empirical study to analyze how waiting in queue in the context of a retail store affects customer purchasing behavior. Our methodology uses a novel technology based on digital imaging to record periodic information about the queuing system. Our econometric method uses queuing theory combining these data with point-of-sales information to estimate the effect of queues on purchases. We find that waiting in queue has a non-linear impact on purchase incidence and that customers appear to focus mostly on the length of the queue, without adjusting enough for the speed at which the line moves. We also find that customers’ sensitivity to waiting is heterogeneous and negatively correlated with price sensitivity. These empirical findings have important implications for service design, staffing and pricing. First, pooling multiple queues into a single queue may increase the length of the queue observed by customers and thereby lead to an increase in lost sales. Second, the model can be used to make staffing decisions, balancing labor costs with revenues. Third, we show that the relationship between price and waiting sensitivity is an important factor for pricing decisions in a multi-product category when congestion effects are present.
A non-linear dynamic model for planetary gear sets

A discrete non-linear torsional vibration model of a single-stage planetary set is proposed in the current study. The model includes all possible power flow configurations, any number of planets in any spacing arrangement and any planet mesh phasing configurations. It also includes time variation of gear mesh stiffnesses as well as clearance (backlash) nonlinearities. The non-linear equations of motion are solved semi-analytically using multi-term harmonic balance method (HBM) in conjunction with inverse discrete Fourier transform and Newton–Rapson method. The HBM solutions are compared with numerical simulation results to demonstrate the accuracy of the HBM formulation. Another comparison with predictions of a deformable-body dynamic model is also provided to assess the accuracy of the discrete model. Limited parametric studies are presented at the end, to show the influence of key gear design parameters on dynamic response.
A Novel Indication for Transvenous Lead Extraction: Upgrading Implantable Cardioverter Defibrillator Systems

Technological advances have resulted in the development of dual chamber pacemaker/defibrillator systems with smaller pectoral 'active cans'. Patients now have the option of upgrading from abdominal to pectoral or from single to dual chamber devices. In addition, due to the potential complications which may arise with abandoned ICD leads, extraction of preexisting leads may be preferable. Methods and Results: Twenty consecutive patients (11 males), underwent lead extraction and upgrade, either from an abdominal to a pectoral, or from a single to a dual chamber device. The mean age was 62±18[emsp4 ]years and mean implant duration was 50±14 months. Indications for extraction included lead fracture/malfunction (13), ERI/EOL (2), new SVT/VT (2), long charge times (2), and impending erosion (1). An initial attempt was made to remove the lead with gentle traction. If excessive scar tissue prohibited extraction, then a laser sheath was employed. Reimplantation proceeded following standard protocol. Clinical success was achieved in all patients. Eleven of thirty leads were removed with traction. The remaining 19 leads required removal with the laser sheath. All ICD reimplants were placed in the left pectoral position, of which 10 were dual chamber. The mean defibrillation threshold was 9.5±5.8 Joules. There were no procedure related perforations or deaths. At follow up (13±10 mos.) there were no infections, lead malfunctions or venous thromboses. There were two deaths, both from intractable heart failure. Conclusions: This study demonstrates that, when indicated, ICD leads can be safely extracted and systems successfully upgraded to take advantage of new technology.