LLukas22/scidocs huggingface dataset:
Rejuvenating the Face: An Analysis of 100 Absorbable Suture Suspension Patients.

Background
Absorbable suture suspension (Silhouette InstaLift, Sinclair Pharma, Irvine, CA) is a novel, minimally invasive system that utilizes a specially manufactured synthetic suture to help address the issues of facial aging, while minimizing the risks associated with historic thread lifting modalities.


Objectives
The purpose of the study was to assess the safety, efficacy, and patient satisfaction of the absorbable suture suspension system in regards to facial rejuvenation and midface volume enhancement.


Methods
The first 100 treated patients who underwent absorbable suture suspension, by the senior author, were critically evaluated. Subjects completed anonymous surveys evaluating their experience with the new modality.


Results
Survey results indicate that absorbable suture suspension is a tolerable (96%) and manageable (89%) treatment that improves age related changes (83%), which was found to be in concordance with our critical review.


Conclusions
Absorbable suture suspension generates high patient satisfaction by nonsurgically lifting mid and lower face and neck skin and has the potential to influence numerous facets of aesthetic medicine. The study provides a greater understanding concerning patient selection, suture trajectory, and possible adjuvant therapies.


Level of Evidence 4
Integration of computer-aided diagnosis/detection (CAD) results in a PACS environment using CAD–PACS toolkit and DICOM SR

Picture Archiving and Communication System (PACS) is a mature technology in health care delivery for daily clinical imaging service and data management. Computer-aided detection and diagnosis (CAD) utilizes computer methods to obtain quantitative measurements from medical images and clinical information to assist clinicians to assess a patient’s clinical state more objectively. CAD needs image input and related information from PACS to improve its accuracy; and PACS benefits from CAD results online and available at the PACS workstation as a second reader to assist physicians in the decision making process. Currently, these two technologies remain as two separate independent systems with only minimal system integration. This paper describes a universal method to integrate CAD results with PACS in its daily clinical environment. The method is based on Health Level 7 (HL7) and Digital imaging and communications in medicine (DICOM) standards, and Integrating the Healthcare Enterprise (IHE) workflow profiles. In addition, the integration method is Health Insurance Portability and Accountability Act (HIPAA) compliant. The paper presents (1) the clinical value and advantages of integrating CAD results in a PACS environment, (2) DICOM Structured Reporting formats and some important IHE workflow profiles utilized in the system integration, (3) the methodology using the CAD–PACS integration toolkit, and (4) clinical examples with step-by-step workflows of this integration.
Nearest Neighbour based Synthesis of Quantum Boolean Circuits

Quantum Boolean circuit synthesis issues are becoming a key area of research in the domain of quantum computing. For gate-level synthesis, minterm based and ReedMuller canonical decomposition techniques are adopted as common approaches. Physical implementation of quantum circuits have inherent constraints and hence nearest neighbour template of input lines is gaining importance. In this work, we present a brief analysis of the various Fixed Polarity Reed Muller (FPRM) expressions for a given quantum Boolean circuit and also introduce the rules for the nearest neighbour template-based synthesis of these forms. The corresponding circuit costs are evaluated.
A Cautionary Note About Policy Conflict Resolution

Policy-based network management promises to deliver a high degree of automation for military network management. A policy-based network management system provides the capability to express networking requirements in the form of policies and have them automatically realized in the network, without requiring further manual updates. However, as with every technology, these benefits come at the expense of certain obvious risks. The biggest risk associated with policy-based management is that the policies themselves can interact in undesirable ways, by causing conflicting actions to be taken by the management system. Thus it is essential that policies be analyzed for conflicts, and that mechanisms be put in place for determining how to resolve these conflicts. A number of policy conflict resolution techniques have been described in the literature; however, they often concentrate on the abstract problem of formal policy analysis and have very little to do with practical policy conflict resolution in live management systems. This paper provides an overview of the state of the art in policy conflict detection and resolution, followed by a critical look at what is really needed to resolve practical policy conflicts in network management systems. The premise of this paper is that application-specific policy conflict detection and resolution can mostly be addressed by careful policy writing (or re-writing), rather than via cumbersome and unrealistically complex policy conflict resolution solutions
KARL JASPERS ON THE FUTURE OF GERMANY

Abstract : This paper presents a review of a book authored by a philosopher who was a resident of Germany during the Nazi regime. It presents briefly Jaspers views on the government of post-war Germany.
A two-stage intelligent search algorithm for the two-dimensional strip packing problem

This paper presents a two-stage intelligent search algorithm for a two-dimensional strip packing problem without guillotine constraint. In the first stage, a heuristic algorithm is proposed, which is based on a simple scoring rule that selects one rectangle from all rectangles to be packed, for a given space. In the second stage, a local search and a simulated annealing algorithm are combined to improve solutions of the problem. In particular, a multi-start strategy is designed to enhance the search capability of the simulated annealing algorithm. Extensive computational experiments on a wide range of benchmark problems from zero-waste to non-zero-waste instances are implemented. Computational results obtained in less than 60 seconds of computation time show that the proposed algorithm outperforms the supposedly excellent algorithms reported recently, on average. It performs particularly better for large instances. 2011 Elsevier B.V. All rights reserved.
External validation of QDSCORE(®) for predicting the 10-year risk of developing Type 2 diabetes.

BACKGROUND
A small number of risk scores for the risk of developing diabetes have been produced but none has yet been widely used in clinical practice in the UK. The aim of this study is to independently evaluate the performance of QDSCORE(®) for predicting the 10-year risk of developing diagnosed Type 2 diabetes in a large independent UK cohort of patients from general practice.


METHODS
A prospective cohort study of 2.4 million patients (13.6 million person years) aged between 25 and 79 years from 364 practices from the UK contributing to The Health Improvement Network (THIN) database between 1 January 1993 and 20 June 2008.


RESULTS
QDSCORE(®) showed good performance data when evaluated on a large external data set. The score is well calibrated with reasonable agreement between observed and predicted outcomes. There is a slight underestimation of risk in both men and women aged 60 years and above, although the magnitude of underestimation is small. The ability of the score to differentiate between those who develop diabetes and those who do not is good, with values for the area under the receiver operating characteristic curve exceeding 0.8 for both men and women. Performance data in this external validation are consistent with those reported in the development and internal validation of the risk score.


CONCLUSIONS
QDSCORE(®) has shown to be a useful tool to predict the 10-year risk of developing Type 2 diabetes in the UK.
Network coordination following discharge from psychiatric inpatient treatment: a study protocol

BACKGROUND
Inadequate discharge planning following inpatient stays is a major issue in the provision of a high standard of care for patients who receive psychiatric treatment. Studies have shown that half of patients who had no pre-discharge contact with outpatient services do not keep their first outpatient appointment. Additionally, discharged patients who are not well linked to their outpatient care networks are at twice the risk of re-hospitalization. The aim of this study is to investigate if the Post-Discharge Network Coordination Program at ipw has a demonstrably significant impact on the frequency and duration of patient re-hospitalization. Subjects are randomly assigned to either the treatment group or to the control group. The treatment group participates in the Post-Discharge Network Coordination Program. The control group receives treatment as usual with no additional social support. Further outcome variables include: social support, change in psychiatric symptoms, quality of life, and independence in daily functioning.


METHODS/DESIGN
The study is conducted as a randomized controlled trial. Subjects are randomly assigned to either the control group or to the treatment group. Computer generated block randomization is used to assure both groups have the same number of subjects. Stratified block randomization is used for the psychiatric diagnosis of ICD-10, F1. Approximately 160 patients are recruited in two care units at Psychiatrie-Zentrum Hard Embrach and two care units at Klinik Schlosstal Winterthur.


DISCUSSION
The proposed post-discharge network coordination program intervenes during the critical post-discharge period. It focuses primarily on promoting the integration of the patients into their social networks, and additionally to coordinating outpatient care and addressing concerns of daily life.


TRIAL REGISTRATION ISRCTN
ISRCTN58280620.
Protein timing and its effects on muscular hypertrophy and strength in individuals engaged in weight-training

The purpose of this review was to determine whether past research provides conclusive evidence about the effects of type and timing of ingestion of specific sources of protein by those engaged in resistance weight training. Two essential, nutrition-related, tenets need to be followed by weightlifters to maximize muscle hypertrophy: the consumption of 1.2-2.0 g protein.kg -1 of body weight, and ≥44-50 kcal.kg-1 of body weight. Researchers have tested the effects of timing of protein supplement ingestion on various physical changes in weightlifters. In general, protein supplementation pre- and post-workout increases physical performance, training session recovery, lean body mass, muscle hypertrophy, and strength. Specific gains, differ however based on protein type and amounts. Studies on timing of consumption of milk have indicated that fat-free milk post-workout was effective in promoting increases in lean body mass, strength, muscle hypertrophy and decreases in body fat. The leucine content of a protein source has an impact on protein synthesis, and affects muscle hypertrophy. Consumption of 3-4 g of leucine is needed to promote maximum protein synthesis. An ideal supplement following resistance exercise should contain whey protein that provides at least 3 g of leucine per serving. A combination of a fast-acting carbohydrate source such as maltodextrin or glucose should be consumed with the protein source, as leucine cannot modulate protein synthesis as effectively without the presence of insulin. Such a supplement post-workout would be most effective in increasing muscle protein synthesis, resulting in greater muscle hypertrophy and strength. In contrast, the consumption of essential amino acids and dextrose appears to be most effective at evoking protein synthesis prior to rather than following resistance exercise. To further enhance muscle hypertrophy and strength, a resistance weight- training program of at least 10-12 weeks with compound movements for both upper and lower body exercises should be followed.
Influence of adding nano-graphite powders on the microstructure and gas hydrogen storage properties of ball-milled Mg90Al10 alloys

Abstract A small quantity of nano-graphite powders were introduced into the Mg 90 Al 10 alloy to obtain the ball milled Mg 90 Al 10 + x wt% graphite ( x  = 0, 1, 3, 5 and 8) composites. The influences of adding nano-graphite powders on the microstructure and hydrogen storage performances were studied. The microstructure analysis showed that adding nano-graphite powders not only promotes the formation of Mg 17 Al 12 phase, but also increases the number of Al atoms that enter into the crystal lattice of Mg. The performance test indicated that adding nano-graphite powders can improve the activation performance and enhance the hydrogenation/dehydrogenation kinetics and capacity. It also is benificial to lower the thermodynamic stability of the hydride. The dehydrogenation enthalpy (Δ H de ) and activation energy ( E de (a)) decrease at different degrees after adding nano-graphite powders. Dehydrogenation enthalpy of the composites is 75.43, 74.63, 73.20, 72.68 and 71.52 kJ mol −1 H 2 when the value of x is 0, 1, 3, 5 and 8, respectively. Dehydrogenation activation energy of the composites is 162.06, 161.26, 159.07, 156.15 and 158.26 kJ mol −1 H 2 when the value of x is 0, 1, 3, 5 and 8, respectively.
Impact of nitazoxanide on sustained virologic response in Egyptian patients with chronic hepatitis C genotype 4: a double-blind placebo-controlled trial.

BACKGROUND
Nitazoxanide, approved for the treatment of Cryptosporidium parvum and Giardia lamblia, was found to inhibit hepatitis C virus replication.


AIM
The aim of this study was to assess the impact of nitazoxanide as an add-on therapy to pegylated interferon α-2a and ribavirin on sustained virologic response (SVR) in patients with chronic hepatitis C.


PATIENTS AND METHODS
A total of 200 patients with chronic hepatitis C were enrolled in the study, assigned randomly in a 1 : 1 ratio to two groups: group A (placebo group) and group B (nitazoxanide group). Five patients withdrew from the study after they signed the consent form.A total of 195 patients were evaluated: 97 patients in group A versus 98 patients in group B at a dose of 500 mg twice daily. Placebo and nitazoxanide were administered as an add-on therapy to pegylated interferon α-2a plus ribavirin following a 12-week lead-in phase. SVR was evaluated. Statistical analysis was carried out using the SPSS software.


RESULTS
The mean age of the patients in group A was 46.5 versus 45.7 years in group B. In group A, 85 out of 97 (87.6%) patients were men and in group B, 84 out of 98 (85.7%) patients were men.In group A, 59 out of 97 (60.82%) patients achieved an SVR versus 57 out of 98 (58.16%) patients in group B (P=0.70); this difference was not significant.


CONCLUSION
Our data did not show any significant impact of nitazoxanide on SVR.
Prevention of selenite-induced cataractogenesis by rutin in Wistar rats

PURPOSE
To investigate whether rutin retards selenite-induced cataractogenesis in Wistar rat pups.


METHODS
On postpartum day ten, Group I rat pups received an intraperitoneal injection of saline. Group II and III rat pups received a subcutaneous injection of sodium selenite. Group III also received an intraperitoneal injection of rutin once daily on postpartum days 9-14. Both eyes of each pup were examined from day 16 up to postpartum day 30. After sacrifice, extricated pup lenses were analyzed for mean activities of catalase, superoxide dismutase, glutathione peroxidase, glutathione S-transferase, and glutathione reductase. In addition, the mean concentrations of reduced glutathione (GSH) and of malondialdehyde were analyzed in samples of lenses and hemolysate.


RESULTS
There was dense lenticular opacification in all of Group II, minimal opacification in 33.3% of Group III, no opacification in 66.7% of Group III, and no opacification in Group I. Significantly lower mean activities of lenticular antioxidant enzymes were noted in Group II, compared to Group I and III. Significantly lower mean concentrations of GSH and higher mean concentrations of malondialdehyde were noted in samples of hemolysate and lens from Group II, compared to the values in Group I and III.


CONCLUSION
Rutin prevents experimental selenite-induced cataractogenesis in rat pups, possibly by preventing depletion of antioxidant enzymes and of GSH, and by inhibiting lipid peroxidation.
Concurrent partnerships and the spread of HIV.

OBJECTIVE
To examine how concurrent partnerships amplify the rate of HIV spread, using methods that can be supported by feasible data collection.


METHODS
A fully stochastic simulation is used to represent a population of individuals, the sexual partnerships that they form and dissolve over time, and the spread of an infectious disease. Sequential monogamy is compared with various levels of concurrency, holding all other features of the infection process constant. Effective summary measures of concurrency are developed that can be estimated on the basis of simple local network data.


RESULTS
Concurrent partnerships exponentially increase the number of infected individuals and the growth rate of the epidemic during its initial phase. For example, when one-half of the partnerships in a population are concurrent, the size of the epidemic after 5 years is 10 times as large as under sequential monogamy. The primary cause of this amplification is the growth in the number of people connected in the network at any point in time: the size of the largest "component'. Concurrency increases the size of this component, and the result is that the infectious agent is no longer trapped in a monogamous partnership after transmission occurs, but can spread immediately beyond this partnership to infect others. The summary measure of concurrency developed here does a good job in predicting the size of the amplification effect, and may therefore be a useful and practical tool for evaluation and intervention at the beginning of an epidemic.


CONCLUSION
Concurrent partnerships may be as important as multiple partners or cofactor infections in amplifying the spread of HIV. The public health implications are that data must be collected properly to measure the levels of concurrency in a population, and that messages promoting one partner at a time are as important as messages promoting fewer partners.
An Optimized Union-Find Algorithm for Connected Components Labeling Using GPUs

In this paper, we report on an optimized union-find (UF) algorithm that can label the connected components on a 2D image efficiently by employing GPU architecture. The proposed method comprises three phases: UF-based local merge, boundary analysis, and link. The coarse labeling in local merge, which makes computation efficient because the length of the labelequivalence list is sharply suppressed . Boundary analysis only manages the cells on the boundary of each thread block to launch fewer CUDA threads. We compared our method with the label equivalence algorithm [1], conventional parallel UF algorithm [2], and line-based UF algorithm [3]. Evaluation results show that the proposed algorithm speeds up the average running time by around 5x, 3x, and 1.3x, respectively.
Deep Learning the City : Quantifying Urban Perception At A Global Scale

Siamese-like networks, Streetscore-CNN (SS-CNN) and Ranking SS-CNN, to predict pairwise comparisons Figure 1: User Interface for Crowdsourced Online Game Performance Analysis • SS-CNN: We calculate the % of pairwise comparisons in test set predicted correctly by (1) Softmax of output neurons in final layer (2) comparing TrueSkill scores [2] obtained from synthetic pairwise comparisons from the CNN (3) extracting features from penultimate layer of CNN and feeding pairwise feature representations to a RankSVM [3] • RSS-CNN: We compare the ranking function outputs for both images in a test pair to decide which image wins, and calculate the binary prediction accuracy.
The polyphase cascaded-cell DC/DC converter

This paper describes a new type of unisolated dc/dc converter employing cascaded converter cells, and its operation is analyzed. The topology and the operation of the converter have similarities with the modular multilevel converter for polyphase ac/dc conversion, but the ac voltages and currents are in this case only employed for redistributing power within the converter. It is shown how the nominal modulation indices for ac and dc voltage influence the semiconductor expenditure for the converter. A methodology for optimizing the design of the converter with regard to the required silicon area is devised. It is found that at voltage conversion ratios close to unity it is preferable to use a combination of full-bridge cells and half-bridge cells. Under such circumstances the proposed converter can offer lower semiconductor expenditure than a conventional buck converter.
HED Meteorites and Their Relationship to the Geology of Vesta and the Dawn Mission

Howardite-eucrite-diogenite (HED) meteorites, thought to be derived from 4 Vesta, provide the best sampling available for any differentiated asteroid. However, deviations in oxygen isotopic composition from a common massfractionation line suggest that a few eucrite-like meteorites are from other bodies, or that Vesta was not completely homogenized during differentiation. The petrology and geochemistry of HEDs provide insights into igneous processes that produced a crust composed of basalts, gabbros, and ultramafic cumulate rocks. Although most HED magmas were fractionated, it is unresolved whether some eucrites may have been primary melts. The geochemistry of HEDs indicates that bulk Vesta is depleted in volatile elements and is relatively reduced, but has chondritic refractory element abundances. The compositions of HEDs may favor a magma ocean model, but inconsistencies remain. Geochronology indicates that Vesta accreted and differentiated within the first several million years of solar system history, that magmatism continued over a span of ~10 Myr, and that its thermal history extended for perhaps 100 Myr. The protracted cooling history is probably responsible for thermal metamorphism of most HEDs. Impact chronology indicates that Vesta experienced many significant collisions, including during the late heavy bombardment. The age of the huge south pole crater is controversial, but it probably ejected Vestoids and many HEDs. Continued impacts produced a regolith composed of eucrite and diogenite fragments containing only minor exotic materials. HED meteorites serve as ground truth for orbital spectroscopic and chemical analyses by the Dawn spacecraft, and their properties are critical for instrument calibration and interpretation of Vesta’s geologic history.
Power Quality Improvements in Isolated Twelve-Pulse AC-DC Converters Using Delta/Double-Polygon Transformer

This paper presents twelve-pulse AC-DC converters for constant current applications. The delta/delta-star transformer based 12-pulse AC-DC converter doesn't meet power quality requirements. To overcome this drawback, a delta/double polygon transformer based AC-DC converter is designed, simulated and developed to compare its performance in terms of power quality parameters with that of delta/delta-star transformer based AC-DC converter. To meet power quality requirement over wide range of load variation, pulse doubling technique is used to make it 24-pulse AC-DC converter.