LLukas22/scidocs huggingface dataset:
SoK: Cryptographically Protected Database Search

Protected database search systems cryptographically isolate the roles of reading from, writing to, and administering the database. This separation limits unnecessary administrator access and protects data in the case of system breaches. Since protected search was introduced in 2000, the area has grown rapidly, systems are offered by academia, start-ups, and established companies. However, there is no best protected search system or set of techniques. Design of such systems is a balancing act between security, functionality, performance, and usability. This challenge is made more difficult by ongoing database specialization, as some users will want the functionality of SQL, NoSQL, or NewSQL databases. This database evolution will continue, and the protected search community should be able to quickly provide functionality consistent with newly invented databases. At the same time, the community must accurately and clearly characterize the tradeoffs between different approaches. To address these challenges, we provide the following contributions:1) An identification of the important primitive operations across database paradigms. We find there are a small number of base operations that can be used and combined to support a large number of database paradigms.2) An evaluation of the current state of protected search systems in implementing these base operations. This evaluation describes the main approaches and tradeoffs for each base operation. Furthermore, it puts protected search in the context of unprotected search, identifying key gaps in functionality.3) An analysis of attacks against protected search for different base queries.4) A roadmap and tools for transforming a protected search system into a protected database, including an open-source performance evaluation platform and initial user opinions of protected search.
Aerosol pentamidine-induced bronchoconstriction. Predictive factors and preventive therapy.

OBJECTIVE
To describe the frequency of aerosol pentamidine-induced bronchoconstriction, its relationship to non-specific airway responsiveness, and its response to preventive therapy using salbutamol, ipratropium bromide, or sodium cromoglycate.


METHODS
Consecutive HIV-infected individuals starting prophylactic AP were eligible if they had not been previously treated with this agent. Simple spirometry was performed before and 10 min after a single 60-mg dose given through an ultrasonic nebulizer. Methacholine challenge was performed in all subjects 24 h to four days after the initial AP dose. Subjects with a change in FEV1 (delta FEV1) greater than or equal to 10 percent decrease after the initial AP dose were restudied on three separate occasions (greater than 24 hours apart) after premedication with two puffs of salbutamol (200 micrograms), ipratropium bromide (40 micrograms), or sodium cromoglycate (2 mg), in random order.


RESULTS
Fifty-three subjects were studied. The median delta FEV1 after a single dose of AP was -7.0 percent (range: -47 percent, 1.8 percent). The delta FEV1 following AP was only partially predicted by the degree of nonspecific bronchial responsiveness as measured by a standard methacholine challenge. Age, current smoking, history of asthma, baseline FEV1, or a prior episode of PCP failed to predict the delta FEV1 following AP. Eighteen subjects (34 percent) had a delta FEV1 greater than or equal to 10 percent decrease (median: -17.0 percent). In these subjects, after premedication with salbutamol, ipratropium bromide, and sodium cromoglycate, the median delta FEV1 was 1.0, 0.8, and -9.6 percent, respectively.


CONCLUSION
Aerosol pentamidine produced a decrease in FEV1 greater than or equal to 10 percent in 34 percent of subjects. This was not accurately predicted by the methacholine response. The bronchoconstriction induced by AP was effectively prevented by either salbutamol or ipratropium, whereas cromoglycate was only partially effective.
Proteus: Exploiting Numerical Precision Variability in Deep Neural Networks

This work exploits the tolerance of Deep Neural Networks (DNNs) to reduced precision numerical representations and specifically, their recently demonstrated ability to tolerate representations of different precision per layer while maintaining accuracy. This flexibility enables improvements over conventional DNN implementations that use a single, uniform representation. This work proposes Proteus, which reduces the data traffic and storage footprint needed by DNNs, resulting in reduced energy and improved area efficiency for DNN implementations. Proteus uses a different representation per layer for both the data (neurons) and the weights (synapses) processed by DNNs. Proteus is a layered extension over existing DNN implementations that converts between the numerical representation used by the DNN execution engines and the shorter, layer-specific fixed-point representation used when reading and writing data values to memory be it on-chip buffers or off-chip memory. Proteus uses a novel memory layout for DNN data, enabling a simple, low-cost and low-energy conversion unit.
 We evaluate Proteus as an extension to a state-of-the-art accelerator [7] which uses a uniform 16-bit fixed-point representation. On five popular DNNs Proteus reduces data traffic among layers by 43% on average while maintaining accuracy within 1% even when compared to a single precision floating-point implementation. As a result, Proteus improves energy by 15% with no performance loss. Proteus also reduces the data footprint by at least 38% and hence the amount of on-chip buffering needed resulting in an implementation that requires 20% less area overall. This area savings can be used to improve cost by building smaller chips, to process larger DNNs for the same on-chip area, or to incorporate an additional three execution engines increasing peak performance bandwidth by 18%.
SMEs Co-opetition and Knowledge Sharing: The IS Role

Co-opetition, simultaneous co-operation and competition, is a recent phenomenon. Co-opetition entails sharing knowledge that may be a key source of competitive advantage. Yet, the knowledge gained by cooperation may also be used for competition. There is little investigation of how this problem may be modeled and, hence, managed. A game-theoretic framework for analysing inter-organisational knowledge sharing under co-opetition and guidelines for the management of explicit knowledge, predicated on co-ordination and control theory has been proposed, but remains untested. This research empirically investigates these issues in the context of small and medium-sized enterprises (SMEs). SMEs provide an interesting setting as they are knowledge generators, but are poor at knowledge exploitation. The paper uses data from UK SMEs to investigate co-opetition, management of knowledge sharing and the role of IS.
Building Better Theory by Bridging the Quantitative-Qualitative Divide

Qualitative methods for data collection and analysis are not mystical, but they are powerful, particularly when used to build new or refine existing theories. This article provides an introduction to qualitative methods and an overview of tactics for ensuring rigor in qualitative research useful for the novice researcher, as well as more experienced researchers interested in expanding their methodological repertoire or seeking guidance on how to evaluate qualitative research. We focus our discussion on the qualitative analytical technique of grounded theory building, and suggest that organizational research has much to gain by coupling of use of qualitative and quantitative research methods.
[HPV prophylactic vaccine coverage and factors impacting its practice among students and high school students in Marseilles' area].

OBJECTIVES
To assess the coverage of HPV vaccine among young women from Marseilles' area and factors influencing the probability of this vaccination.


MATERIALS AND METHODS
An anonymous survey was conducted among 2124 high school and university students from Marseilles' area, France from December 2011 to May 2012.


RESULTS
Mean age of participants was 20.4years (±SD: 3.3). Only 41.6% participants reported being vaccinated against HPV, of whom 768 (93.3) had completed the 3 injections scheme. Among non-vaccinated respondents, 33.6% acknowledged they would accept a catch-up vaccination. Factors influencing the probability of being vaccinated were young age (AOR: 0.728; 95% CI: 0.681-0.779; P<0.001), socioeconomic and/or education level of parents (AOR: 1.324; 95% CI: 1.006-1.742; P=0.045), information about vaccination (AOR: 24.279; 95% CI: 5.417-108.82; P<0.001) and having a general practitioner (GP) favourable to vaccination (AOR: 68.776; 95% CI: 34.511-137.061; P<0.001). Factors influencing the probability to accept a catch-up vaccination were age (AOR: 1.059; 95% CI: 1.001-1.120; P=0.046), socioeconomic and/or education level of parents (AOR: 1.637; 95% CI: 1.198-2.237; P=0.002) and having a GP favourable to vaccination (AOR: 4.381; 95% CI: 2.978-6.445; P<0.001). Only 35.5% of respondents were aware that screening remains necessary following HPV vaccination.


CONCLUSION
The coverage of HPV vaccine among young women from Marseilles' area is insufficient. Factors influencing the probability of being vaccinated against HPV are age, socioeconomic and/or education level of parents and information regarding vaccination. GP plays a major role in the acceptance of HPV vaccine.
Therapeutic effect of continuous exercise training program on serum creatinine concentration in men with hypertension: a randomized controlled trial.

BACKGROUND
Creatinine (Cr) has been implicated as an independent predictor of hypertension and exercise has been reported as adjunct therapy for hypertension. The purpose of the present study was to investigate the effect of continuous training programme on blood pressure and serum creatinine concentration in black African subjects with hypertension.


METHODS
Three hundred and fifty seven male patients with mild to moderate (systolic blood pressure [SBP] between 140-180 & diastolic blood pressure [DBP] between 90-109 mmHg) essential hypertension were age matched and randomly grouped into continuous & control groups. The continuous group involved in an 8 weeks continuous training (60-79% HR reserve) of between 45 minutes to 60 minutes, 3 times per week, while the control group remain sedentary. SBP, DBP, VO2max, serum Cr, body mass index (BMI), waist hip ratio (WHR) and percent (%) body fat. Analysis of covariance (ANCOVA) and Pearson correlation tests were used in data analysis.


RESULTS
Findings of the study revealed significant decreased effects of continuous training programme on SBP, DBP, Cr, BMI, WHR, % body fat and significant increase in VO2max at p< 0.05. Serum Cr is significantly and negatively correlated with SBP (-.335), DBP (.194), BMI (.268), WHR (-.258) and % body fat (-.190) at p<0.05.


CONCLUSION
The present study demonstrated a rationale bases for the adjunct therapeutic role of moderate intensity continuous exercise training as a multi-therapy in the down regulation of blood pressure, serum Cr, body size and body fat in hypertension.
Glass Ceiling Effect : A Focus on Pakistani Women

Glass ceiling and gender discrimination are the biggest barriers holding back Pakistani women from occupying high positions of prestige in the corporate world. Working women in Pakistan face obstacles moving up the corporate ladder and are often excluded from the decision-making. The present research paper looks into the prevailing situation of glass ceiling effect from Pakistani workingwomen’s perspective along with barriers and while concluding the discussion makes recommendations to the relevant stake holders.
The contribution of South African curricula to prepare health professionals for working in rural or under-served areas in South Africa: a peer review evaluation.

SETTING
The Collaboration for Health Equity through Education and Research (CHEER) was formed in 2003 to examine strategies that would increase the production of health professionals who choose to practise in rural and under-served areas in South Africa.


OBJECTIVES
We aimed to identify how each faculty is preparing its students for service in rural or under-served areas.


METHODS
Peer reviews were conducted at all nine participating universities. A case study approach was used, with each peer review constituting its own study but following a common protocol and tools. Each research team comprised at least three reviewers from different universities, and each review was conducted over at least 3 days on site. The participating faculties were assessed on 11 themes, including faculty mission statements, resource allocation, student selection, first exposure of students to rural and under-served areas, length of exposure, practical experience, theoretical input, involvement with the community, relationship with the health service, assessment of students and research and programme evaluation.


RESULTS
With a few exceptions, most themes were assessed as inadequate or adequate with respect to the preparation of students for practice in rural or under-served areas after qualification, despite implicit intentions to the contrary at certain faculties.


CONCLUSIONS
Common challenges, best practices and potential solutions have been identified through this project. Greater priority must be given to supporting rural teaching sites in terms of resources and teaching capacity, in partnership with government agencies.
Randomized Trial Comparing Off-Pump to On-Pump Coronary Artery Bypass Grafting in High-Risk Patients ( # 2003-13903

Objective: The subset of patients most likely to benefit from off-pump coronary artery bypass grafting (CABG) remains a controversial issue, but the technique has been proposed to decrease postoperative mortality and morbidity. The objective of this study was to compare off-pump to on-pump CABG in patients with known risk factors for mortality and morbidity. 65 high-risk patients were prospectively randomized to undergo off-pump or on-pump CABG. Recruited patients had at least 3 of the following criteria: age greater than 65 years, high blood pressure, diabetes, serum creatinine greater than 133 ␮mol/L, left ventricular ejection fraction lower than 45%, chronic pulmonary disease, unstable angina, congestive heart failure, repeat CABG, anemia, and carotid atherosclerosis. Hospital mortality and morbidity were the primary end-points of the study. Results: Six patients (9%) crossed over from the original randomized group. Twenty-eight patients averaging 70 ± 8 years of age underwent 3 ± 1 grafts off pump, and 37 patients averaging 70 ± 6 years of age underwent 3.4 ± 1 grafts on pump. Revascularization was considered complete in 21 (75%) of off-pump patients compared to 33 (89%) of on-pump patients (P = .1). There were no hospital deaths in off-pump patients, and 2 patients (5%) undergoing on-pump CABG died early following surgery (P = .2). Two off-pump (7%) compared to 11 on-pump (30%) of patients presented composite end-points including death, neurolog-ical injury, renal failure, respiratory failure, and operative myocardial infarction after CABG (P = .02). Conclusion: The present study suggests that off-pump CABG, when technically feasible, significantly reduces morbidity following surgery in a group of high-risk patients. Coronary artery bypass grafting (CABG) is currently performed with or without the use of the cardiopulmonary bypass system (CPB). Although both techniques are being used with success [Van Dijk 2001], a debate is raging between advocates and opponents of off-pump CABG about patient outcomes and surgical indications for one or the other technique [Bonchek 2002]. Several authors have suggested that off-pump CABG could be especially useful and effective in improving clinical outcomes in high-risk patients who require surgical revascu-larization [Hoff 2002, Al-Ruzzeh 2003]. Elderly patients and those with significant comorbidities are more susceptible to the deleterious effects of CPB and are most likely to benefit from the use of off-pump CABG compared to the standard on-pump approach [Demaria 2002]. The objective of the present study was to compare outcomes between off-pump CABG and a standard technique of CABG with …
A Comprehensive Study of Progressive Cytogenetic Alterations in Clear Cell Renal Cell Carcinoma and a New Model for ccRCC Tumorigenesis and Progression

We present a comprehensive study of cytogenetic alterations that occur during the progression of clear cell renal cell carcinoma (ccRCC). We used high-density high-throughput Affymetrix 100 K SNP arrays to obtain the whole genome SNP copy number information from 71 pretreatment tissue samples with RCC tumors; of those, 42 samples were of human ccRCC subtype. We analyzed patterns of cytogenetic loss and gain from different RCC subtypes and in particular, different stages and grades of ccRCC tumors, using a novel algorithm that we have designed. Based on patterns of cytogenetic alterations in chromosomal regions with frequent losses and gains, we inferred the involvement of candidate genes from these regions in ccRCC tumorigenesis and development. We then proposed a new model of ccRCC tumorigenesis and progression. Our study serves as a comprehensive overview of cytogenetic alterations in a collection of 572 ccRCC tumors from diversified studies and should facilitate the search for specific genes associated with the disease.
Lifetime cost-effectiveness of skin cancer prevention through promotion of daily sunscreen use.

OBJECTIVES
Health-care costs for the treatment of skin cancers are disproportionately high in many white populations, yet they can be reduced through the promotion of sun-protective behaviors. We investigated the lifetime health costs and benefits of sunscreen promotion in the primary prevention of skin cancers, including melanoma.


METHODS
A decision-analytic model with Markov chains was used to integrate data from a central community-based randomized controlled trial conducted in Australia and other epidemiological and published sources. Incremental cost per quality-adjusted life-year was the primary outcome. Extensive one-way and probabilistic sensitivity analyses were performed to test the uncertainty in the base findings with plausible variation to the model parameters.


RESULTS
Using a combined household and government perspective, the discounted incremental cost per quality-adjusted life-year gained from the sunscreen intervention was AU$40,890. Over the projected lifetime of the intervention cohort, this would prevent 33 melanomas, 168 cutaneous squamous-cell carcinomas, and 4 melanoma-deaths at a cost of approximately AU$808,000. The likelihood that the sunscreen intervention was cost-effective was 64% at a willingness-to-pay threshold of AU$50,000 per quality-adjusted life-year gained.


CONCLUSIONS
Subject to the best-available evidence depicted in our model, the active promotion of routine sunscreen use to white populations residing in sunny settings is likely to be a cost-effective investment for governments and consumers over the long term.
Intravitreal triamcinolone acetonide in sympathetic ophthalmia

To report the result of intravitreal triamcinolone acetonide in the treatment of sympathetic ophthalmia. A 29-year-old woman who suffered from sympathetic ophthalmia and who was being treated with systemic corticosteroid therapy received an intravitreal injection of 4 mg of triamcinolone acetonide. By the 15th day after injection visual acuity had improved from 20/200 to 20/40 and serous retinal detachment had almost completely resorbed. Systemic corticosteroid therapy was reduced sequentially. By the third month after injection, the patient was in clinical remission. Her visual acuity was 20/20 and no serous detachment was observed. In this study, short-term improvement in the clinical picture of a patient with sympathetic ophthalmia after intravitreal triamcinolone acetonide injection was described. The results suggest that intravitreal triamcinolone acetonide injection may be an additional tool in the treatment of sympathetic ophthalmia.
Melody Extraction on Vocal Segments Using Multi-Column Deep Neural Networks

Singing melody extraction is a task that tracks pitch contour of singing voice in polyphonic music. While the majority of melody extraction algorithms are based on computing a saliency function of pitch candidates or separating the melody source from the mixture, data-driven approaches based on classification have been rarely explored. In this paper, we present a classification-based approach for melody extraction on vocal segments using multi-column deep neural networks. In the proposed model, each of neural networks is trained to predict a pitch label of singing voice from spectrogram, but their outputs have different pitch resolutions. The final melody contour is inferred by combining the outputs of the networks and post-processing it with a hidden Markov model. In order to take advantage of the data-driven approach, we also augment training data by pitch-shifting the audio content and modifying the pitch label accordingly. We use the RWC dataset and vocal tracks of the MedleyDB dataset for training the model and evaluate it on the ADC 2004, MIREX 2005 and MIR-1k datasets. Through several settings of experiments, we show incremental improvements of the melody prediction. Lastly, we compare our best result to those of previous state-of-the-arts.
Foggy clouds and cloudy fogs: a real need for coordinated management of fog-to-cloud computing systems

The recent advances in cloud services technology are fueling a plethora of information technology innovation, including networking, storage, and computing. Today, various flavors have evolved of IoT, cloud computing, and so-called fog computing, a concept referring to capabilities of edge devices and users' clients to compute, store, and exchange data among each other and with the cloud. Although the rapid pace of this evolution was not easily foreseeable, today each piece of it facilitates and enables the deployment of what we commonly refer to as a smart scenario, including smart cities, smart transportation, and smart homes. As most current cloud, fog, and network services run simultaneously in each scenario, we observe that we are at the dawn of what may be the next big step in the cloud computing and networking evolution, whereby services might be executed at the network edge, both in parallel and in a coordinated fashion, as well as supported by the unstoppable technology evolution. As edge devices become richer in functionality and smarter, embedding capacities such as storage or processing, as well as new functionalities, such as decision making, data collection, forwarding, and sharing, a real need is emerging for coordinated management of fog-to-cloud (F2C) computing systems. This article introduces a layered F2C architecture, its benefits and strengths, as well as the arising open and research challenges, making the case for the real need for their coordinated management. Our architecture, the illustrative use case presented, and a comparative performance analysis, albeit conceptual, all clearly show the way forward toward a new IoT scenario with a set of existing and unforeseen services provided on highly distributed and dynamic compute, storage, and networking resources, bringing together heterogeneous and commodity edge devices, emerging fogs, as well as conventional clouds.
Extracting relevant knowledge for the detection of sarcasm and nastiness in the social web

Automatic detection of emotions like sarcasm or nastiness in online written conversation is a difficult task. It requires a system that can manage some kind of knowledge to interpret that emotional language is being used. In this work, we try to provide this knowledge to the system by considering alternative sets of features obtained according to different criteria. We test a range of different feature sets using two different classifiers. Our results show that the sarcasm detection task benefits from the inclusion of linguistic and semantic information sources, while nasty language is more easily detected using only a set of surface patterns or indicators. 2014 Elsevier B.V. All rights reserved.