LLukas22/scidocs huggingface dataset:
Reliability-Centered Maintenance for Wind Turbines Based on Statistical Analysis and Practical Experience

The concept of reliability-centered maintenance (RCM) is applied to the two wind-turbine models Vestas V44-600 kW and V90-2MW. The executing RCM workgroup includes an owner and operator of the analyzed wind turbines, a maintenance service provider, a provider of condition-monitoring services, and wind-turbine component supplier as well as researchers at academia. Combining the results of failure statistics and assessment of expert judgement, the analysis is focused on the most critical subsystems with respect to failure frequencies and consequences: the gearbox, the generator, the electrical system, and the hydraulic system. This study provides the most relevant functional failures, reveals their causes and underlying mechanisms, and identifies remedial measures to prevent either the failure itself or critical secondary damage. This study forms the basis for the development of quantitative models for maintenance strategy selection and optimization, but may also provide a feedback of field experience for further improvement of wind-turbine design.
Shoulder-surfing resistance with eye-gaze entry in cued-recall graphical passwords

We present Cued Gaze-Points (CGP) as a shoulder-surfing resistant cued-recall graphical password scheme where users gaze instead of mouse-click. This approach has several advantages over similar eye-gaze systems, including a larger password space and its cued-recall nature that can help users remember multiple distinct passwords. Our 45-participant lab study is the first evaluation of gaze-based password entry via user-selected points on images. CGP's usability is potentially acceptable, warranting further refinement and study.
The Visual Analysis of Human Movement: A Survey

The ability to recognize humans and their activities by vision is key for a machine to interact intelligently and effortlessly with a human-inhabited environment. Because of many potentially important applications, “looking at people” is currently one of the most active application domains in computer vision. This survey identifies a number of promising applications and provides an overview of recent developments in this domain. The scope of this survey is limited to work on whole-body or hand motion; it does not include work on human faces. The emphasis is on discussing the various methodologies; they are grouped in 2-D approaches with or without explicit shape models and 3-D approaches. Where appropriate, systems are reviewed. We conclude with some thoughts about future directions. c © 1999 Academic Press
Advancing ambiguity

Ambiguity is an important concept for HCI because of its pervasiveness in everyday life, yet its emergent nature challenges the role of design. We examine these difficulties with regards to Aoki and Woodruff's [1] proposal to use ambiguity as a resource for designing space for stories in personal communication systems. We challenge certain assumptions about ambiguity and propose a set of design and evaluation guidelines that flow from this re-conceptualization of ambiguity and design.
State of Charge Estimation of Battery Energy Storage Systems Based on Adaptive Unscented Kalman Filter With a Noise Statistics Estimator

Since the noise statistics of large-scale battery energy storage systems (BESSs) are often unknown or inaccurate in actual applications, the estimation precision of state of charge (SOC) of BESSs using extended Kalman filter (EKF) or unscented Kalman filter (UKF) is usually inaccurate or even divergent. To resolve this problem, a method based on adaptive UKF (AUKF) with a noise statistics estimator is proposed to estimate accurately SOC of BESSs. The noise statistics estimator based on the modified Sage-Husa maximum posterior is aimed to estimate adaptively the mean and error covariance of measurement and system process noises online for the AUKF when the prior noise statistics are unknown or inaccurate. The accuracy and adaptation of the proposed method is validated by the comparison with the UKF and EKF under different real-time conditions. The comparison shows that the proposed method can achieve better SOC estimation accuracy when the noise statistics of BESSs are unknown or inaccurate.
Alzheimer's disease and Parkinson's disease.

N Engl J Med 2003;348:1356-64. Copyright © 2003 Massachusetts Medical Society. he incidence of many common diseases is increased among the relatives of affected patients, but the pattern of inheritance rarely follows Mendel’s laws. Instead, such common diseases are thought to result from a complex interaction among multiple predisposing genes and other factors, including environmental contributions and chance occurrences. Identifying the genetic contribution to such complex diseases is a major challenge for genomic medicine. However, as so clearly foreseen nearly 350 years ago by the English physiologist William Harvey, 1 finding the genetic basis for rarer, mendelian forms of a disease may illuminate the etiologic process and pathogenesis of the more common, complex forms. This is illustrated in the progress made in understanding Alzheimer’s disease and Parkinson’s disease through the investigation of the rare, clearly inherited forms of these diseases. The molecular basis of neurodegenerative disorders was reviewed in the Journal in 1999. 2
An integrated 6 MV linear accelerator model from electron gun to dose in a water tank

Purpose: The details of a full simulation of an inline side-coupled 6 MV linear accelerator linac from the electron gun to the target are presented. Commissioning of the above simulation was performed by using the derived electron phase space at the target as an input into Monte Carlo studies of dose distributions within a water tank and matching the simulation results to measurement data. This work is motivated by linac-MR studies, where a validated full linac simulation is first required in order to perform future studies on linac performance in the presence of an external magnetic field. Methods: An electron gun was initially designed and optimized with a 2D finite difference program using Child’s law. The electron gun simulation served as an input to a 6 MV linac waveguide simulation, which consisted of a 3D finite element radio-frequency field solution within the waveguide and electron trajectories determined from particle dynamics modeling. The electron gun design was constrained to match the cathode potential and electron gun current of a Varian 600C, while the linac waveguide was optimized to match the measured target current. Commissioning of the full simulation was performed by matching the simulated Monte Carlo dose distributions in a water tank to measured distributions. Results: The full linac simulation matched all the electrical measurements taken from a Varian 600C and the commissioning process lead to excellent agreements in the dose profile measurements. Greater than 99% of all points met a 1%/1mm acceptance criterion for all field sizes analyzed, with the exception of the largest 40 40 cm2 field for which 98% of all points met the 1%/1mm acceptance criterion and the depth dose curves matched measurement to within 1% deeper than 1.5 cm depth. The optimized energy and spatial intensity distributions, as given by the commissioning process, were determined to be non-Gaussian in form for the inline side-coupled 6 MV linac simulated. Conclusions: An integrated simulation of an inline side-coupled 6 MV linac has been completed and benchmarked matching all electrical and dosimetric measurements to high accuracy. The results showed non-Gaussian spatial intensity and energy distributions for the linac modeled. © 2010 American Association of Physicists in Medicine. DOI: 10.1118/1.3397455
The effect of antihypertensive agents on sleep apnea: protocol for a randomized controlled trial

BACKGROUND
Obstructive sleep apnea (OSA) and hypertension are well-known cardiovascular risk factors. Their control could reduce the burden of heart disease across populations. Several drugs are used to control hypertension, but the only consistently effective treatment of OSA is continuous positive airway pressure. The identification of a drug capable of improving OSA and hypertension simultaneously would provide a novel approach in the treatment of both diseases.


METHODS/DESIGN
This is a randomized double-blind clinical trial, comparing the use of chlorthalidone with amiloride versus amlodipine as a first drug option in patients older than 40 years of age with stage I hypertension (140 to 159/90 to 99 mmHg) and moderate OSA (15 to 30 apneas/hour of sleep). The primary outcomes are the variation of the number of apneas per hour and blood pressure measured by ambulatory blood pressure monitoring. The secondary outcomes are adverse events, somnolence scale (Epworth), ventilatory parameters and C reactive protein levels. The follow-up will last 8 weeks. There will be 29 participants per group. The project has been approved by the ethics committee of our institution.


DISCUSSION
The role of fluid retention in OSA has been known for several decades. The use of diuretics are well established in treating hypertension but have never been appropriately tested for sleep apnea. As well as testing the efficacy of these drugs, this study will help to understand the mechanisms that link hypertension and sleep apnea and their treatment.


TRIAL REGISTRATION
ClinicalTrials.gov: NCT01896661.
The phonological unit of Japanese Kanji compounds: A masked priming investigation.

Using the masked priming paradigm, we examined which phonological unit is used when naming Kanji compounds. Although the phonological unit in the Japanese language has been suggested to be the mora, Experiment 1 found no priming for mora-related Kanji prime-target pairs. In Experiment 2, significant priming was only found when Kanji pairs shared the whole sound of their initial Kanji characters. Nevertheless, when the same Kanji pairs used in Experiment 2 were transcribed into Kana, significant mora priming was observed in Experiment 3. In Experiment 4, matching the syllable structure and pitch-accent of the initial Kanji characters did not lead to mora priming, ruling out potential alternative explanations for the earlier absence of the effect. A significant mora priming effect was observed, however, when the shared initial mora constituted the whole sound of their initial Kanji characters in Experiments 5. Lastly, these results were replicated in Experiment 6. Overall, these results indicate that the phonological unit involved when naming Kanji compounds is not the mora but the whole sound of each Kanji character. We discuss how different phonological units may be involved when processing Kanji and Kana words as well as the implications for theories dealing with language production processes. (PsycINFO Database Record
Postallograft lenalidomide induces strong NK cell-mediated antimyeloma activity and risk for T cell-mediated GvHD: Results from a phase I/II dose-finding study.

Lenalidomide may prevent relapses after allogeneic stem cell transplantation by promoting the immune-mediated graft-versus-tumor effect. We performed a prospective phase I/II study to define the dose-limiting toxicity and the immunologic effects of lenalidomide given early (day 100-180) after allograft for four cycles in patients with multiple myeloma. According to the Fibonacci design, 24 patients with a median age of 53 years were included. Dose-limiting toxicity was organ toxicity owing to graft-versus-host disease, and the maximum tolerable dose was 5 mg. The incidence of graft-versus-host disease after lenalidomide was 38%, occurring after a median of 22 days, and was beside organ toxicity, a leading cause to discontinue the study in 29% of the patients. Immune monitoring revealed a significant increase in peripheral γ-interferon-secreting CD4(+) and CD8(+) T cells within the first week of lenalidomide treatment followed by a delayed increase in T regulatory cells. Furthermore, natural killer (NK) cells isolated from the peripheral blood of patients evidenced a significantly improved antimyeloma activity after lenalidomide treatment. The immune effect might have contributed to the increased CR rate from 24-42% after lenalidomide treatment because nonresponding patients showed significantly less natural killer and T cell activation. (Study registered under: NCT 00778752.).
Counteracting tinnitus by acoustic coordinated reset neuromodulation.

PURPOSE
Subjective tinnitus is associated with pathologic enhanced neuronal synchronization. We used a model based desynchronization technique, acoustic coordinated reset (CR) neuromodulation, to specifically counteract tinnitus-related neuronal synchrony thereby inducing an unlearning of pathological synaptic connectivity and neuronal synchrony.


METHODS
In a prospective, randomized, single blind, placebo-controlled trial in 63 patients with chronic tonal tinnitus and up to 50 dB hearing loss we studied safety and efficacy of different doses of acoustic CR neuromodulation. We measured visual analogue scale and tinnitus questionnaire (TQ) scores and spontaneous EEG.


RESULTS
CR treatment was safe, well-tolerated and caused a significant decrease of tinnitus loudness and symptoms. Placebo treatment did not lead to any significant changes. Effects gained in 12 weeks of treatment persisted through a preplanned 4-week therapy pause and showed sustained long-term effects after 10 months of therapy: response, i.e. a reduction of at least 6 TQ points, was obtained in 75% of patients with a mean TQ reduction of 50% among responders. CR therapy significantly lowered tinnitus frequency and reversed the tinnitus related EEG alterations.


CONCLUSION
The CR-induced reduction of tinnitus and underlying neuronal characteristics indicates a new non-invasive therapy which might also be applicable to other conditions with neuronal hypersynchrony.
Existence of Solutions to First-Order Periodic Boundary Value Problems

This article investigates the existence of solutions to boundary value problems (BVPs) involving systems of first-order ordinary differential equations and two-point, periodic boundary conditions. The methods involve novel differential inequalities and fixed-point theory to yield new theorems guaranteeing the existence of at least one solution. AMS 2000 Classification: 34B15
Diagnosis of Lung Cancer Prediction System Using Data Mining Classification Techniques

Cancer is the most important cause of death for both men and women. The early detection of cancer can be helpful in curing the disease completely. So the requirement of techniques to detect the occurrence of cancer nodule in early stage is increasing. A disease that is commonly misdiagnosed is lung cancer. Earlier diagnosis of Lung Cancer saves enormous lives, failing which may lead to other severe problems causing sudden fatal end. Its cure rate and prediction depends mainly on the early detection and diagnosis of the disease. One of the most common forms of medical malpractices globally is an error in diagnosis. Knowledge discovery and data mining have found numerous applications in business and scientific domain. Valuable knowledge can be discovered from application of data mining techniques in healthcare system. In this study, we briefly examine the potential use of classification based data mining techniques such as Rule based, Decision tree, Naïve Bayes and Artificial Neural Network to massive volume of healthcare data. The healthcare industry collects huge amounts of healthcare data which, unfortunately, are not “mined” to discover hidden information. For data preprocessing and effective decision making One Dependency Augmented Naïve Bayes classifier (ODANB) and naive creedal classifier 2 (NCC2) are used. This is an extension of naïve Bayes to imprecise probabilities that aims at delivering robust classifications also when dealing with small or incomplete data sets. Discovery of hidden patterns and relationships often goes unexploited. Diagnosis of Lung Cancer Disease can answer complex “what if” queries which traditional decision support systems cannot. Using generic lung cancer symptoms such as age, sex, Wheezing, Shortness of breath, Pain in shoulder, chest, arm, it can predict the likelihood of patients getting a lung cancer disease. Aim of the paper is to propose a model for early detection and correct diagnosis of the disease which will help the doctor in saving the life of the patient. Keywords—Lung cancer, Naive Bayes, ODANB, NCC2, Data Mining, Classification.
Vehicle trajectory optimization for application in ECO-driving

To reduce fuel consumption in the transportation sector research focuses mainly on the development of more efficient drive train technologies and alternative drive train designs. Another and immidiately applicable way found to reduce fuel consumption in road vehicles is to change vehicle operation such that system efficiency is maximized. The concept of Eco-driving refers to the change of driver behavior in a fuel saving way or more generally in an energy saving way. In this paper system efficiency of a vehicle is optimized using a dynamic programming optimization approach. Given a drive cycle a so called ‘eco-drive cycle’ is identified in which a vehicle performs the same distance with the same stops in equivalent time, while consuming less fuel.
Cooking fuel choices and garbage burning practices as determinants of birth weight: a cross-sectional study in Accra, Ghana

BACKGROUND
Effect of indoor air pollution (IAP) on birth weight remains largely unexplored but yet purported as the most important environmental exposure for pregnant women in developing countries due to the effects of second-hand smoke. We investigated the associations between the determinants of indoor air quality in households and birth weight.


METHODS
A cross-sectional study of 592 mothers and their newborns using postnatal services at the Korle Bu Teaching Hospital located in Accra, Ghana was conducted in 2010 to collect information on characteristics of indoor environment and other potential determinants of fetal growth. Birth weight was recorded from hospital records.


RESULTS
Household cooking fuel choices and garbage burning practices were determinants of birth weight. Multivariate linear regression analysis adjusting for age, social class, marital status and gravidity of mothers, and sex of neonate resulted in a 243 g (95% CI: 496, 11) and 178g (95% CI: 421, 65) reduction in birth weight for use of charcoal, and garbage burning respectively compared with use of LPG only. The estimated reductions in birth weight was not statistically significant. Applying the ordinal scale exposure parameter nonetheless revealed a significant exposure-response relationship between maternal exposures from charcoal use and garbage burning, and birth weight. Generalized linear models adjusting for confounders resulted in a 41% (risk ratio [RR] = 1.41; 95% CI: 0.62, 3.23) and 195% (RR=2.95; 95% CI: 1.10, 7.92) increase in the risk of low birth weight (LBW) for use of charcoal, and garbage burning respectively compared with use of LPG only. A combination of charcoal use and household garbage burning during pregnancy on fetal growth resulted in a 429 g (95% CI: 259, 599) reduction in birth weight and 316% (RR=4.16; 95% CI: 2.02, 8.59) excess risk of LBW. Sensitivity analysis performed by restricting the analysis to term births produced similar results.


CONCLUSIONS
Maternal use of charcoal as a cooking fuel during pregnancy and burning of garbage at home are strong determinants of average fetal growth and risk of LBW. Efforts to reduce maternal exposures to IAP are thus important to improve birth outcomes.
A phase II trial of gemcitabine and weekly high-dose 5-fluorouracil in a 48-hour continuous-infusion schedule in patients with advanced pancreatic carcinoma. A study of the Spanish Cooperative Group for Gastrointestinal Tumour Therapy (TTD).

AIM
A multi-centred, open-labelled, phase 11 study containing 46 patients was conducted to evaluate the clinical benefit of gemcitabine (1,400 mg/m(2)) combined with 5-FU (3 g/m(2)) in a 48 h continuous infusion (CI).


METHODS
Both drugs were administered on days 1, 8 and 15 of every 4 week cycle in chemotherapy-naïve patients with locally advanced unresectable metastatic pancreatic carcinoma. The minimum follow-up was 6 months.


RESULTS
Clinical benefit response was the primary endpoint and this was achieved by 24.4% of the patients. Quality of life (QoL) improved in 16.6% of patients. Objective response was observed in 7% of the patients. The median progression-free survival (PFS) was 14.4 weeks and the median overall survival (OS) time was 22.7 weeks. One-year survival was 25%. The most frequent grade 3-4 toxicities were neutropenia (45%), mucositis (7.5%) and hyperbilirubinaemia (10.5%).


CONCLUSIONS
This schedule was not superior in terms of clinical benefit, response rate, PFS and OS than standard gemcitabine treatment
Miricatena prunicola (Hyphomycetes), a new genus and species causing leaf spots of Prunus serotina in the UK

A fungus causing conspicuous leaf spots of Prunus serotina was recently collected in Surrey, UK. It proved to represent an undescribed species which also cannot be referred to any known genus. The species is described as Miricatena prunicola gen. et sp. nov.
Seasonal Work in the Memory of the People of Apátistvánfalva

V pricujocem prispevku so predstavljeni izsledki terenske raziskave o sezonskem zaposlovanju prebivalcev Stevanovcev (južni del Porabja) med obema vojnama, ko je bilo med vascani sezonsko delo se zmeraj razsirjeno. Na sezonskem delu zasluženi pridelek je bil pomemben vir za preživetje družin. Vecmesecno bivanje na posestvih v razlicnih županijah na Madžarskem, kakor tudi v Nemciji, je pustilo globoke sledi v spominu Stevanovcanov. Pricevanja nekdanjih sezonskih delavcev so pomemben vir pri preucevanju sezonskega zaposlovanja porabskih Slovencev. *** The paper focuses on the findings of a fieldwork research on seasonal work practices of the people of Apatistvanfalva (Stevanovci in Slovenian) in the south of Porabje, an area situated in a triangle between Hungary, Slovenia, and Austria. In the period between the First and the Second World Wars, seasonal work was still a significant source of income for the local population. The time spent working in different regions of Hungary as well as Germany, which usually lasted several months, has remained very much alive in the memories of the villagers of Stevanovci. Recounts of former seasonal workers and their family members represent an important source for the study of seasonal work of Slovenians from Porabje.
WCAG 2.0: a web accessibility standard for the evolving web

Since the Web Content Accessibility Guidelines 1.0 (WCAG) became a W3C recommendation in May 1999, the Web has changed dramatically. This paper describes some of the major issues encountered because of these changes and the approaches developed to address them in WCAG 2.0.