LLukas22/scidocs huggingface dataset:
FAIR AND BALANCED? QUANTIFYING MEDIA BIAS THROUGH CROWDSOURCED CONTENT ANALYSIS CEREN BUDAK*

It is widely thought that news organizations exhibit ideological bias, but rigorously quantifying such slant has proven methodologically challenging. Through a combination of machinelearning and crowdsourcing techniques, we investigate the selection and framing of political issues in fifteen major US news outlets. Starting with 803,146 news stories published over twelve months, we first used supervised learning algorithms to identify the 14 percent of articles pertaining to political events. We then recruited 749 online human judges to classify a random subset of 10,502 of these political articles according to topic and ideological position. Our analysis yields an ideological ordering of outlets consistent with prior work. However, news outlets are considerably more similar than generally believed. Specifically, with the exception of political scandals, major news organizations present topics in a largely nonpartisan manner, casting neither Democrats nor Republicans in a particularly favorable or unfavorable light. Moreover, again with the exception of political scandals, little evidence exists of systematic differences in story selection, with all major news outlets covering a wide variety of topics with frequency largely unrelated to the outlet’s ideological position. Finally, news organizations express their ideological bias not by directly advocating for a preferred political party, but rather by disproportionately criticizing one side, a convention that further moderates overall differences. Ceren Budak is an assistant professor in the School of Information at the University of Michigan, Ann Arbor, MI, USA. Sharad Goel is an assistant professor in the Management Science and Engineering Department at Stanford University, Palo Alto, CA, USA. Justin M. Rao is a senior researcher at Microsoft Research, Redmond, WA, USA. The authors thank Seth Flaxman, Matthew Salganik, and Sid Suri for comments. *Address correspondence to Ceren Budak, University of Michigan, School of Information, 105 S. State St. Ann Arbor, MI 48109-1285, USA; e-mail: cbudak@umich.edu. Public Opinion Quarterly, Vol. 80, Special Issue, 2016, pp. 250–271 doi:10.1093/poq/nfw007
Pulse Rate Variability Analysis for Discrimination of Sleep-Apnea-Related Decreases in the Amplitude Fluctuations of Pulse Photoplethysmographic Signal in Children

A technique for ambulatory diagnosis of the obstructive sleep apnea syndrome (OSAS) in children based on pulse photoplethysmographic (PPG) signal is presented. Decreases in amplitude fluctuations of the PPG signal (DAP) events have been proposed as OSAS discriminator, since they are related to vasoconstriction associated to apnea. Heart rate variability (HRV) analysis during these DAP events has been proposed to discriminate between DAP events related or unrelated to an apneic event. The use of HRV requires electrocardiogram (ECG) as an additional recording, meaning a disadvantage that takes more relevance in sleep studies context where the number of sensors is tried to be minimized in order not to affect the physiological sleep. This study proposes the use of pulse rate variability (PRV) extracted from the PPG signal instead of HRV. Polysomnographic registers from 21 children (aged 4.47 ±2.04 years) were studied. The subject classification based on DAP events and PRV analysis obtained an accuracy of 86.67% which represents an improvement of 6.67% with respect to the HRV analysis. These results suggest that PRV can be used in apnea detectors based on DAP events, to discriminate apneic from nonapneic events avoiding the need for ECG recordings.
Generative Art Inspired by Nature, Using NodeBox

NodeBox is a free application for producing generative art. This paper gives an overview of the nature-inspired functionality in NodeBox and the artworks we created using it. We demonstrate how it can be used for evolutionary computation in the context of computer games and art, and discuss some of our recent research with the aim to simulate (artistic) brainstorming using language processing techniques and semantic networks.
The "army of lost souls".

The VA works with federal, state, and community agencies to ameliorate the homeless veteran problem and some of its causes. Virtual Mentor is a monthly bioethics journal published by the American Medical Association.
Controlled release formulation of tramadol hydrochloride using hydrophilic and hydrophobic matrix system

The effect of concentration of hydrophilic (hydroxypropyl methylcellulose [HPMC]) and hydrophobic polymers (hydrogenated castor oil [HCO], ethylcellulose) on the release rate of tramadol was studied. Hydrophilic matrix tablets were prepared by wet granulation technique, while hydrophobic (wax) matrix tablets were prepared by melt granulation technique and in vitro dissolution studies were performed using United States Pharmacopeia (USP) apparatus type II. Hydrophobic matrix tablets resulted in sustained in vitro drug release (>20 hours) as compared with hydrophilic matrix tablets (<14 hours). The presence of ethylcellulose in either of the matrix systems prolonged the release rate of the drug. Tablets prepared by combination of hydrophilic and hydrophobic polymers failed to prolong the drug release beyond 12 hours. The effect of ethylcellulose coating (Surelease) and the presence of lactose and HPMC in the coating composition on the drug release was also investigated. Hydrophobic matrix tablets prepared using HCO were found to be best suited for modulating the delivery of the highly water-soluble drug, tramadol hydrochloride.
The role of Internet addiction in online game loyalty: an exploratory study

Purpose – The paper’s aim is to explore the factors that affect the online game addiction and the role that online game addiction plays in the relationship between online satisfaction and loyalty. Design/methodology/approach – A web survey of online game players was conducted, with 1,186 valid responses collected. Structure equation modeling – specifically partial least squares – was used to assess the relationships in the proposed research framework. Findings – The results indicate that perceived playfulness and descriptive norms influence online game addiction. Furthermore, descriptive norms indirectly affect online game addiction through perceived playfulness. Addiction also directly contributes to loyalty and attenuates the relationship between satisfaction and loyalty. This finding partially explains why people remain loyal to an online game despite being dissatisfied. Practical implications – Online gaming vendors should strive to create amusing game content and to maintain their online game communities in order to enhance players’ perceptions of playfulness and the effects of social influences. Also, because satisfaction is the most significant indicator of loyalty, vendors can enhance loyalty by providing better services, such as fraud prevention and the detection of cheating behaviors. Originality/value – The value of this study is that it reveals the moderating influences of addiction on the satisfaction-loyalty relationship and factors that contribute to the online game addiction. Moreover, while many past studies focused on addiction’s negative effects and on groups considered particularly vulnerable to Internet addiction, this paper extends previous work by investigating the relationship of addiction to other marketing variables and by using a more general population, mostly young adults, as research subjects.
Ionizing Radiation Induces Stemness in Cancer Cells

The cancer stem cell (CSC) model posits the presence of a small number of CSCs in the heterogeneous cancer cell population that are ultimately responsible for tumor initiation, as well as cancer recurrence and metastasis. CSCs have been isolated from a variety of human cancers and are able to generate a hierarchical and heterogeneous cancer cell population. CSCs are also resistant to conventional chemo- and radio-therapies. Here we report that ionizing radiation can induce stem cell-like properties in heterogeneous cancer cells. Exposure of non-stem cancer cells to ionizing radiation enhanced spherogenesis, and this was accompanied by upregulation of the pluripotency genes Sox2 and Oct3/4. Knockdown of Sox2 or Oct3/4 inhibited radiation-induced spherogenesis and increased cellular sensitivity to radiation. These data demonstrate that ionizing radiation can activate stemness pathways in heterogeneous cancer cells, resulting in the enrichment of a CSC subpopulation with higher resistance to radiotherapy.
A sequential compression mechanical pump to prevent hypotension during elective cesarean section under spinal anesthesia.

BACKGROUND
Spinal anesthesia is a standard technique for cesarean section but can cause hypotension which may be related to venous pooling secondary to progesterone-induced decreases in vascular tone. This study investigated the use of a sequential compression mechanical pump with thigh-high sleeves with compression cycles timed to venous refilling. We hypothesized that this would recruit pooled venous blood from the lower limbs, maintain the central blood volume and thus decrease the incidence of hypotension.


METHODS
One hundred parturients scheduled for elective cesarean section under spinal anesthesia were recruited and randomly assigned to use of either a mechanical pump (Group M) or control (Group C). A standardized protocol for co-hydration and anesthesia was followed. Hypotension, defined as a decrease in systolic blood pressure by >20% from baseline, was treated with 6-mg boluses of intravenous ephedrine. The incidence of hypotension was defined as the primary outcome. Median ephedrine requirement was taken as a measure of the severity of hypotension.


RESULTS
Hypotension occurred in 12 of 47 (25.5%) patients in Group M compared to 27 of 45 (60%) in Group C (P=0.001). The median [range] ephedrine dose was greater in Group C (12 [0-24]mg) compared to Group M (0 [0-12]mg) (P<0.001). There was no difference between groups in the time to onset of hypotension.


CONCLUSION
The use of a sequential compression mechanical pump that detects venous refilling and cycles accordingly, reduced the incidence and severity of hypotension after spinal anesthesia for cesarean section.
Visual coverage and scanning behavior in two corvid species: American crow and Western scrub jay

Inter-specific differences in the configuration of avian visual fields and degree of eye/head movements have been associated with foraging and anti-predator behaviors. Our goal was to study visual fields, eye movements, and head movements in two species of corvids: American crow (Corvus brachyrhynchos) and Western scrub jay (Aphelocoma californica). American crows had wider binocular overlap, longer vertical binocular fields, narrower blind areas, and higher amplitude of eye movement than Western scrub jays. American crows can converge their eyes and see their own bill tip, which may facilitate using different foraging techniques (e.g., pecking, probing) and manufacturing and handing rudimentary tools. Western scrub jays had a higher head movement rate than American crows while on the ground, and the opposite between-species difference was found when individuals were perching. Faster head movements may enhance the ability to scan the environment, which may be related to a higher perceived risk of predation of Western scrub jays when on the ground, and American crows when perching. The visual field configuration of these species appears influenced mostly by foraging techniques while their scaning behavior, by predation risk.
Empirical Evaluation of Profile Characteristics for Gender Classification on Twitter

Online Social Networks (OSNs) provide reliable communication among users from different countries. The volume of texts generated by OSNs is huge and highly informative. Gender classification can serve commercial organizations for advertising, law enforcement for legal investigation, and others for social reasons. Here we explore profile characteristics for gender classification on Twitter. Unlike existing approaches to gender classification that depend heavily on posted text such as tweets, here we study the relative strengths of different characteristics extracted from Twitter profiles (e.g., first name and background color in a user's profile page). Our goal is to evaluate profile characteristics with respect to their predictive accuracy and computational complexity. In addition, we provide a novel technique to reduce the number of features of text-based profile characteristics from the order of millions to a few thousands and, in some cases, to only 40 features. We prove the validity of our approach by examining different classifiers over a large dataset of Twitter profiles.
A comparison between low intensity and reduced intensity conditioning in allogeneic hematopoietic stem cell transplantation for solid tumors.

BACKGROUND
Following different types of conditioning, allogeneic hematopoietic stem cell transplantation produces a graft-versus-tumor effect in patients with solid tumors. We performed a non-randomized study comparing low intensity conditioning with reduced intensity conditioning after stem cell transplantation to demonstrate the graft-versus-tumor effect.


DESIGN AND METHODS
Allogeneic stem cell transplantation was performed in 48 patients with metastatic renal cell cancer (n=17), colo-rectal cancer (n=15), non-metastatic advanced primary liver cancer after orthotopic liver transplantation (n=11), and other solid tumors (n=5). Tumor response was determined based on the international response evaluation criteria for solid tumors (RECIST).


RESULTS
No significant difference in the incidence of graft rejection was found between the low intensity conditioning and reduced intensity conditioning groups. Engraftment occurred earlier in the low intensity conditioning group than in the reduced intensity conditioning group (median 0 vs. 16 days, respectively; p<0.001). Complete donor chimerism in B cells occurred earlier after low intensity conditioning than after reduced intensity conditioning (median 28 vs. 97 days, respectively; p<0.001). No significant difference in the incidence of tumor response was found between groups receiving the different types of the conditioning. The most favorable tumor response rate was found in patients who received donor lymphocyte infusions and developed chronic graft-versus-host disease (75% vs. 34%, p=0.003). The best graft-versus-tumor effect was demonstrated in patients with advanced primary liver cancer who had previously undergone liver transplantation (p=0.018). Patients receiving reduced intensity conditioning had a tendency to better overall survival compared to the low intensity conditioning group (30% vs. 17%, p=0.005).


CONCLUSIONS
Adjuvant cell therapy with donor lymphocyte infusion may augment the graft-versus-tumor effect of chronic graft-versus-host disease. Patients with limited tumor load are indicated for allogeneic stem cell transplantation and reduced intensity conditioning may be favorable compared to low intensity conditioning.
Neuroprotection by freezing ischemic penumbra evolution without cerebral blood flow augmentation with a postsynaptic density-95 protein inhibitor.

BACKGROUND AND PURPOSE
The purpose of this study was to determine whether neuroprotection is feasible without cerebral blood flow augmentation in experimental permanent middle cerebral artery occlusion.


METHODS
Rats were subjected to permanent middle cerebral artery occlusion by the suture occlusion method and were treated 1 hour thereafter with a single 5-minute intravenous infusion of the postsynaptic density-95 protein inhibitor Tat-NR2B9c (7.5 mg/kg) or saline (n=8/group). Arterial spin-labeled perfusion-weighted MRI and diffusion weighted MRI were obtained with a 4.7-T Bruker system at 30, 45, 70, 90, 120, 150, and 180 minutes postmiddle cerebral artery occlusion to determine cerebral blood flow and apparent diffusion coefficient maps, respectively. At 24 hours, animals were neurologically scored (0 to 5), euthanized, and the brains stained with 2-3-5-triphenyl tetrazolium chloride to ascertain infarct volumes corrected for edema. Additionally, the effects of Tat-NR2B9c on adenosine 5'-triphosphate levels were measured in vitro in neurons subjected to oxygen-glucose deprivation.


RESULTS
Final infarct volume was decreased by 30.3% in the Tat-NR2B9c-treated animals compared with controls (P=0.028). There was a significant improvement in 24 hours neurological scores in the Tat-NR2B9c group compared with controls, 1.8±0.5 and 2.8±1.0, respectively (P=0.021). Relative to controls, Tat-NR2B9c significantly attenuated diffusion-weighted imaging lesion growth and preserved the diffusion-weighted imaging/perfusion-weighted imaging mismatch (ischemic penumbra) without affecting cerebral blood flow in the ischemic core or penumbra. Tat-NR2B9c treatment of primary neuronal cultures resulted in 26% increase in cell viability and 34% greater adenosine 5'-triphosphate levels after oxygen-glucose deprivation.


CONCLUSIONS
Preservation of adenosine 5'-triphosphate levels in vitro and neuroprotection in permanent middle cerebral artery occlusion in rats is achievable without cerebral blood flow augmentation using a postsynaptic density-95 protein inhibitor.
ALDH2, ADH1B, and ADH1C Genotypes in Asians: A Literature Review

Variants of three genes encoding alcohol-metabolizing enzymes, the aldehyde dehydrogenase gene ALDH2 and the alcohol dehydrogenase genes ADH1B and ADH1C, have been associated with reduced rates of alcohol dependence. The genotype prevalence of these genes varies in general samples of different Asian ethnic groups. The ALDH2*2 allele appears to be most prevalent in Chinese-American, Han Chinese and Taiwanese, Japanese, and Korean samples. Much lower rates have been reported in Thais, Filipinos, Indians, and Chinese and Taiwanese aborigines. ADH1B*2 is highly prevalent among Asians, with the exception of Indians. ADH1C*1 also is highly prevalent in Asians, but has only been examined in a few studies of Chinese and Korean samples.
Birth Preparedness and Complication Readiness among Pregnant Women in Southern Ethiopia

BACKGROUND
Birth preparedness and complication preparedness (BPACR) is a key component of globally accepted safe motherhood programs, which helps ensure women to reach professional delivery care when labor begins and to reduce delays that occur when mothers in labor experience obstetric complications.


OBJECTIVE
This study was conducted to assess practice and factors associated with BPACR among pregnant women in Aleta Wondo district in Sidama Zone, South Ethiopia.


METHODS
A community based cross sectional study was conducted in 2007, on a sample of 812 pregnant women. Data were collected using pre-tested and structured questionnaire. The collected data were analyzed by SPSS for windows version 12.0.1. The women were asked whether they followed the desired five steps while pregnant: identified a trained birth attendant, identified a health facility, arranged for transport, identified blood donor and saved money for emergency. Taking at least two steps was considered being well-prepared.


RESULTS
Among 743 pregnant women only a quarter (20.5%) of pregnant women identified skilled provider. Only 8.1% identified health facility for delivery and/or for obstetric emergencies. Preparedness for transportation was found to be very low (7.7%). Considerable (34.5%) number of families saved money for incurred costs of delivery and emergency if needed. Only few (2.3%) identified potential blood donor in case of emergency. Majority (87.9%) of the respondents reported that they intended to deliver at home, and only 60(8%) planned to deliver at health facilities. Overall only 17% of pregnant women were well prepared. The adjusted multivariate model showed that significant predictors for being well-prepared were maternal availing of antenatal services (OR = 1.91 95% CI; 1.21-3.01) and being pregnant for the first time (OR = 6.82, 95% CI; 1.27-36.55).


CONCLUSION
BPACR practice in the study area was found to be low. Effort to increase BPACR should focus on availing antenatal care services.
Imaging in gynecological disease (5): clinical and ultrasound characteristics in fibroma and fibrothecoma of the ovary.

OBJECTIVES
To describe the clinical and ultrasound features of fibroma and fibrothecoma of the ovary.


METHODS
Sixty-eight women with a histological diagnosis of fibroma or fibrothecoma of the ovary who had undergone a preoperative ultrasound examination between 1999 and 2007 were identified from the databases of four ultrasound centers. The tumors were characterized on the basis of ultrasound images, ultrasound reports and research protocols (when applicable) using the terms and definitions of the International Ovarian Tumor Analysis (IOTA) group. In 51 patients, ultrasound information had been collected prospectively; in the remaining 17 cases it was retrieved retrospectively from ultrasound reports and images. In 44 cases, electronic ultrasound images of good quality were available. These were reviewed by two observers, who described them using pattern recognition.


RESULTS
Of the 68 patients identified, 53 had fibroma and 15 had fibrothecoma. The mean patient age was 54 (range, 17-80) years. Sixty-three percent (41/65) were postmenopausal and 60% (39/65) had no symptoms. Most (75%; 51/68) fibromas/fibrothecomas were solid tumors and most (75%; 51/68) manifested minimal or moderate blood flow on color Doppler examination. Using pattern recognition, all solid fibromas/fibrothecomas were described as round, oval or slightly lobulated tumors. Most (66%; 29/44) were solid tumors, with regular or slightly irregular internal echogenicity with stripy shadows, and some contained cystic spaces. Others (23%, 10/44) were solid tumors with regular or slightly irregular internal echogenicity without stripy shadows and with or without cystic spaces. Two were solid tumors that were so dense it was difficult to assess their internal echogenicity, two were multilocular solid tumors with large cystic spaces and one was described as being mainly cystic. Half of the women with fibroma/fibrothecoma had fluid in the pouch of Douglas and 16% (11/68) had ascites; CA 125 titers > or =35 U/mL were found in 34% (17/50) of the cases in which CA 125 results were available.


CONCLUSIONS
Most fibromas and fibrothecomas are round, oval or lobulated solid tumors that cast stripy shadows and are associated with fluid in the pouch of Douglas, and most manifest minimal to moderate vascularization. A fibroma/fibrothecoma with atypical ultrasound appearance may be mistaken for a malignancy, in particular if associated with fluid in the pouch of Douglas or ascites, high color content and raised CA 125 levels.