LLukas22/scidocs huggingface dataset:
Factors affecting ERP system adoption: A comparative analysis between SMEs and large companies

Purpose – Proposes providing an insight about enterprise resource planning (ERP) adoption, highlighting contact points and significant differences between the way small to medium-sized enterprises (SMEs) and large companies approach such a task. Design/methodology/approach – The research is based on a wide literature review, focused on the identification of a taxonomy of business and organizational factors influencing ERP adoption. The deriving research model was incorporated in a questionnaire that was preliminarily tested and finally provided to a sample of 366 companies of any size. Responses were collected through personal interviews made by a dedicated team to a top manager. Findings – The analysis of the empirical data shows that business complexity, as a composed factor, is a weak predictor of ERP adoption, whereas just company size turns out to be a very good one. In other words, companies seem to be disregarding ERP systems as an answer to their business complexity. Unexpectedly, SMEs disregard financial constraints as the main cause for ERP system non-adoption, suggesting structural and organizational reasons as major ones. This pattern is partially different from what was observed in large organizations where the first reason for not adopting an ERP system is organizational. Moreover, the decision process regarding the adoption of ERP systems within SMEs is still more affected by exogenous reasons or “opportunity of the moment” than business-related factors, contrary to large companies that are more interested in managing process integration and data redundancy/inconsistency through ERP implementation. Research limitations/implications – The research model is based on the assumption that business complexity and organizational change are the most relevant variables influencing ERP adoption, and such variables are explained through a set of factors inherently limited by the results of the literature review. Practical implications – The results of the empirical research provide indication to SMEs willing to take into consideration the adoption of an ERP system. The same outcomes could be incorporated into the development strategies of ERP software houses. Originality/value – This paper contributes to enhancing the understanding of the factors influencing the evolution of information systems within SMEs with respect to large companies.
External root resorption after orthodontic treatment: a study of contributing factors

PURPOSE
The purpose of this study was to examine the patient- and treatment-related etiologic factors of external root resorption.


MATERIALS AND METHODS
This study consisted of 163 patients who had completed orthodontic treatments and taken the pre- and post-treatment panoramic and lateral cephalometric radiographs. The length of tooth was measured from the tooth apex to the incisal edge or cusp tip on the panoramic radiograph. Overbite and overjet were measured from the pre- and post-treatment lateral cephalometric radiographs. The root resorption of each tooth and the factors of malocclusion were analyzed with an analysis of variance. A paired t test was performed to compare the mean amount of root resorption between male and female, between extraction and non-extraction cases, and between surgery and non-surgery groups. Correlation coefficients were measured to assess the relationship between the amount of root resorption and the age in which the orthodontic treatment started, the degree of changes in overbite and overjet, and the duration of treatment.


RESULTS
Maxillary central incisor was the most resorbed tooth, followed by the maxillary lateral incisor, the mandibular central incisor, and the mandibular lateral incisor. The history of tooth extraction was significantly associated with the root resorption. The duration of orthodontic treatment was positively correlated with the amount of root resorption.


CONCLUSION
These findings show that orthodontic treatment should be carefully performed in patients who need the treatment for a long period and with a pre-treatment extraction of teeth.
Drug–Drug Interaction Studies: Regulatory Guidance and An Industry Perspective

Recently, the US Food and Drug Administration and European Medicines Agency have issued new guidance for industry on drug interaction studies, which outline comprehensive recommendations on a broad range of in vitro and in vivo studies to evaluate drug–drug interaction (DDI) potential. This paper aims to provide an overview of these new recommendations and an in-depth scientifically based perspective on issues surrounding some of the recommended approaches in emerging areas, particularly, transporters and complex DDIs. We present a number of theoretical considerations and several case examples to demonstrate complexities in applying (1) the proposed transporter decision trees and associated criteria for studying a broad spectrum of transporters to derive actionable information and (2) the recommended model-based approaches at an early stage of drug development to prospectively predict DDIs involving time-dependent inhibition and mixed inhibition/induction of drug metabolizing enzymes. We hope to convey the need for conducting DDI studies on a case-by-case basis using a holistic scientifically based interrogative approach and to communicate the need for additional research to fill in knowledge gaps in these areas where the science is rapidly evolving to better ensure the safety and efficacy of new therapeutic agents.
Randomized clinical trial of oral and intravenous versus intravenous antibiotic prophylaxis for laparoscopic colorectal resection.

BACKGROUND
The use of oral prophylactic antibiotics for the prevention of surgical-site infection (SSI) in patients undergoing laparoscopic surgery for colorectal cancer is controversial. The aim of this RCT was to evaluate whether intravenous perioperative antibiotics are inferior to combined preoperative oral and perioperative intravenous antibiotics in this setting.


METHODS
Patients undergoing elective laparoscopic colorectal resection in a single cancer centre were assigned randomly to combined preoperative oral antibiotics (metronidazole and kanamycin) and perioperative intravenous antibiotics (cefmetazole) (oral/IV group) or to perioperative intravenous antibiotics (cefmetazole) alone (IV-only group). Patients were stratified for the analyses based on type of operation (colonic surgery, anterior resection or abdominoperineal resection), preoperative use of mechanical bowel preparation, preoperative chemoradiotherapy and the presence of diabetes mellitus. The primary endpoint was the overall rate of SSI. Secondary endpoints were the rates of incisional site infection, organ/space infection, anastomotic leakage, intra-abdominal abscess, adverse events and postoperative complications.


RESULTS
Of 540 patients offered participation in the trial in 2013-2014, 515 agreed to take part and were randomized. Some 256 patients in the IV-only group and 255 in the oral/IV group completed the treatment per protocol. The overall rate of SSI was 7·8 per cent (20 of 256) in the IV-only group and 7·8 per cent (20 of 255) in the oral/IV group, confirming that perioperative administration of intravenous antibiotics alone was not inferior to the combined regimen (P = 0·017). There were no differences in rates of incisional site infection (5·5 versus 5·9 per cent respectively), organ/space infection (2·3 versus 2·0 per cent) or other secondary endpoints between the two groups.


CONCLUSION
Intravenous perioperative antimicrobial prophylaxis alone is not inferior to combined preoperative oral and intravenous perioperative prophylaxis with regard to SSI in patients with colorectal cancer undergoing elective laparoscopic resection. Registration number: UMIN000019339 ( http://www.umin.ac.jp/ctr/).
Automatic Hashtag Recommendation for Microblogs using Topic-Specific Translation Model

Microblogging services continue to grow in popularity, users publish massive instant messages every day through them. Many tweets are marked with hashtags, which usually represent groups or topics of tweets. Hashtags may provide valuable information for lots of applications, such as retrieval, opinion mining, classification, and so on. However, since hashtags should be manually annotated, only 14.6% tweets contain them (Wang et al., 2011). In this paper, we adopt topic-specific translation model(TSTM) to suggest hashtags for microblogs. It combines the advantages of both topic model and translation model. Experimental result on dataset crawled from real world microblogging service demonstrates that the proposed method can outperform some state-of-the-art methods. TITLE AND ABSTRACT IN CHINESE
Results of provisional stenting with a Sirolimus-eluting stent for bifurcation lesion: multicenter study in Japan.

BACKGROUND
Treatment of bifurcation lesion with a drug-eluting stent (DES) remains problematic. The purpose of this study was to investigate an appropriate treatment strategy for bifurcation lesion with a Sirolimus-eluting stent (SES).


METHOD
One-hundred-forty-one patients with 169 bifurcation lesions were treated at three centers in Japan using a Sirolimus-eluting stent. Forty-six lesions (39 patients) were treated on side branches, and provisional stenting was performed in these cases. We evaluated the angiographic results and clinical outcomes with this strategy. Patients with acute myocardial infarction were excluded.


RESULT
After a follow-up period of 184 +/- 65 days, there were no deaths or myocardial infarction (MI), and only one (2.0%) target lesion revascularization (TLR). The strategies used for side-branch treatment were balloon only (83.7%) and T or Modified T stent (16.3%). The final kissing balloon technique was performed on 53.4% overall. In patients with a 6-month follow-up angiogram who had 25 bifurcation lesions (including 5 LMT bifurcation Lesions, 6 LCX-OM Lesions, 13 LAD-Dx lesions, and 1 RCA lesion) that were treated with balloon only, the percent diameter stenosis (%DS) of the side branch at follow-up was similar to that after the procedure (47.2 +/- 34.4% vs. 46.4 +/- 24.1%).


CONCLUSIONS
In the treatment of bifurcation lesions using a SES, the results of provisional stenting for the side branch are acceptable. Percent DS of the side branch remained unchanged over time after PCI.
THE ARENA PRODUCT FAMILY : ENTERPRISE MODELING SOLUTIONS

Organizations throughout the world are quickly moving adopt process modeling and simulation as an integral of their business decision-making and continuo improvement initiatives. With wider acceptance simulation, these consumers are demanding tools support a breadth of applications, scale to fit differe needs through a project life cycle, and integrated w corporate modeling and database systems. Systems Modeling fulfills these needs in the Are product family, encompassing Arena  Business, Standard and Professional Editions for mapping processes simulating discrete and continuous systems; Call$im  for call-center analysis; and HiSpeed$im  for high-speed production-line modeling. These products compleme each other in meeting the various needs for simulation an enterprise via a common software interface a compatible features, providing a natural growth path simulation needs expand. This paper introduces the Arena suite of products modeling and simulation, highlighting product architectu and technology features that are targeted toward succe deployment of simulation and Arena throughout enterprise.
Surveillance of transmitted HIV drug resistance among women attending antenatal clinics in Dar es Salaam, Tanzania.

BACKGROUND
In resource-limited settings where antiretroviral treatment (ART) access is being scaled-up, the World Health Organization (WHO) recommends surveillance of transmitted HIV drug resistance (HIVDR). We used the WHO HIVDR threshold survey method to assess transmitted HIVDR in Dar es Salaam where ART was introduced in 1995 and where approximately 11,000 people are currently on ART.


METHODS
From November 2005 to February 2006, dried blood spot (DBS) specimens were made from remnant specimens collected during the national HIV serosurvey from 60 primagravidas <25 years old attending six antenatal clinics for routine syphilis testing. Genotyping was performed at the Centers for Disease Control and Prevention, Atlanta, Georgia, USA. Protease and reverse transcriptase drug resistance mutations were identified using the Stanford University HIV drug resistance database. We used the National Institutes of Health genotyping tool for HIV-1 subtyping. HIVDR prevalence categorization was based on the WHO threshold survey binomial sequential sampling method.


RESULTS
Among the 60 eligible specimens collected, 50 DBS were successfully amplified using RT-PCR. Sequencing was performed on the first 39 specimens: 13 (33.3%) were subtype A1, 13 (33.3%) subtype C, and 4 (10.3%) subtype D, the remainder differed in the closest subtype based on protease versus reverse transcriptase. No resistance mutations were seen; HIVDR to all drug classes was categorized as <5%.


CONCLUSIONS
Our survey indicates that prevalence of transmitted HIVDR among recently infected pregnant women in Dar es Salaam is low (<5/%). The survey should be repeated during the next HIV sentinel survey in Dar es Salaam and extended to other regions where ART is being scaled up.
The Orchid MADS-Box Genes Controlling Floral Morphogenesis

Orchids are known for both their floral diversity and ecological strategies. The versatility and specialization in orchid floral morphology, structure, and physiological properties have fascinated botanists for centuries. In floral studies, MADS-box genes contributing to the now famous ABCDE model of floral organ identity control have dominated conceptual thinking. The sophisticated orchid floral organization offers an opportunity to discover new variant genes and different levels of complexity to the ABCDE model. Recently, several remarkable research studies done on orchid MADS-box genes have revealed the important roles on orchid floral development. Knowledge about MADS-box genes' encoding ABCDE functions in orchids will give insights into the highly evolved floral morphogenetic networks of orchids.
Development of nanocomposite lead-free electronic solders

Inert, hybrid inorganic/organic, nano-structured chemicals, can be incorporated into low melting metallic materials, such as lead-free electronic solders to achieve desired level of performance. The nano-structured materials technology of polyhedral oligomeric silsesquioxanes (POSS), with appropriate organic groups, can produce suitable means to promote bonding between nano-reinforcements and the metallic matrix. The microstructures of lead-free solder with surface-active POSS tri-silanols were evaluated using scanning electron microscopy (SEM). Wettability of POSS-containing lead-free solders to copper substrate was also examined. Steady-state deformation of solder joints made of eutectic Sn-Ag solder with varying weight fraction of POSS of different chemical moieties were evaluated at a range of temperatures (25/spl deg/C, 100/spl deg/C, and 150/spl deg/C) using a Rheometric Solids Analyzer (RSA-III). Mechanical properties such as shear stress versus simple shear-strain relationships, peak shear stress as a function of rate of simple shear-strain and testing temperature were reported. The service reliability of joints made with these newly formulated nanocomposite solders was evaluated using a realistic thermomechanical fatigue (TMF) profile. Evolution of microstructures and residual mechanical property at different extend of TMF cycles were compared with joints made of standard, un-reinforced eutectic Sn-Ag solder.
Semantic trajectory-based high utility item recommendation system

http://dx.doi.org/10.1016/j.eswa.2014.01.042 0957-4174/ 2014 Elsevier Ltd. All rights reserved. ⇑ Corresponding author. Fax: +886 6 2747076. E-mail addresses: jashying@gmail.com (J.-C. Ying), spide0606@gmail.com (H.-S. Chen), linwc@kuas.edu.tw (K.W. Lin), eric@idb.csie.ncku.edu.tw (E.H.-C. Lu), tsengsm@mail.ncku.edu.tw (V.S. Tseng), hwtsai@itri.org.tw (H.-W. Tsai), itriA00432@ itri.org.tw (K.H. Cheng), jason.lin@itri.org.tw (S.-C. Lin). Jia-Ching Ying , Huan-Sheng Chen , Kawuu W. Lin , Eric Hsueh-Chan Lu , Vincent S. Tseng a,⇑, Huan-Wen Tsai , Kuang Hung Cheng , Shun-Chieh Lin c
Low x phenomena

We review recent developments in the application of perturbative QCD to phenomena at small x.
Quantum Information Set Decoding Algorithms

The security of code-based cryptosystems such as the McEliece cryptosystem relies primarily on the difficulty of decoding random linear codes. The best decoding algorithms are all improvements of an old algorithm due to Prange: they are known under the name of information set decoding techniques. It is also important to assess the security of such cryptosystems against a quantum computer. This research thread started in [22] and the best algorithm to date has been Bernstein’s quantising [5] of the simplest information set decoding algorithm, namely Prange’s algorithm. It consists in applying Grover’s quantum search to obtain a quadratic speed-up of Prange’s algorithm. In this paper, we quantise other information set decoding algorithms by using quantum walk techniques which were devised for the subset-sum problem in [6]. This results in improving the worst-case complexity of 2 of Bernstein’s algorithm to 2 with the best algorithm presented here (where n is the codelength).
The impact of transoral robotic surgery on the overall treatment of oropharyngeal cancer patients.

OBJECTIVES/HYPOTHESIS
To assess adjuvant therapy in patients undergoing surgical management of oropharyngeal squamous cell carcinoma (OPSCCA) with transoral robotic surgery (TORS) and neck dissection.


STUDY DESIGN
A prospective, nonrandomized, consecutive patient series from two separate protocols in a tertiary academic medical center.


METHODS
Patients undergoing treatment for OPSCCA were selected from a prospective protocol evaluating functional and oncologic outcomes following TORS with a comparator group of OPSCCA patients receiving definitive chemoradiotherapy (CRT) participating in a separate prospective protocol.


RESULTS
Forty-two patients represented the TORS group and 38 the CRT group. Twenty (48%) of the TORS patients received surgery only, whereas nine (21%) underwent adjuvant radiotherapy and 13 (31%) adjuvant CRT. Adjuvant therapy patients had a higher overall T (P =.0007) and N (P < .0001) stage than the TORS-only group. Surgery resulted in stage changes in 18 (43%) patients, leading to alteration in therapy for nine (21%) patients. The 3-year overall survival (OS), disease-specific survival (DSS), and locoregional control was 74% versus 90% (P = .30), 94% versus 94% (P = .91), and 72% versus 91% (P = .19) for the TORS-alone versus TORS plus adjuvant therapy groups, respectively. Comparison with the CRT group revealed a survival benefit in the TORS group approaching significance, with a 3-year OS of 83% versus 57% (P = .06) and DSS of 94% versus 85% (P = .08), respectively.


CONCLUSIONS
Primary surgical management of OPSCCA with TORS and neck dissection provides accurate staging information, which can lead to the appropriate selection of subsequent therapy. This approach does not compromise survival and warrants additional investigation.


LEVEL OF EVIDENCE
3b.
Casino gaming and local employment trends

C asino gaming has become a major industry in the United States over the past two decades. Prior to the late 1980s, casino gaming was legal only in Nevada and Atlantic City, New Jersey. Today, casino gaming is available in 29 states. As a consequence, annual gaming revenue has grown from $9 billion in 1991 to over $40 billion in 2001.1 Americans spend more money in casinos than individually on golf, on-screen movies, CDs and sound equipment, and cable TV.2 The casino industry consists of two major parties—Indian tribes and publicly traded private corporations such as Harrah’s Entertainment and Trump Hotels and Casino Resorts. The Indian Gaming Regulatory Act (Public Law 100-497, passed in 1988) allows Indian tribes to own and operate casinos on their reservations. Tribal gaming is available in 25 states and generates nearly $13 billion in annual revenue. Corporate casino gaming is available in 10 states and generated over $27 billion in revenue in 2001.3 Table 1 provides a listing of these states.4 While tribal gaming is available in more states, corporate casino gaming has traditionally been perceived as a more appropriate tool for fostering general economic development through increased employment and tax revenue.5 The primary reason for this perception is that states have no power to tax Indian casino revenue because Indian reservations are sovereign entities, distinct from the state.6 While states and Indian tribes do cooperate on regulation and security issues (dictated by state-tribal gaming compacts), the relationship between a tribe and a state is very similar to the relationship between two states—one state generally cannot legally dictate what another state can do. Corporate casinos, however, are private industries that are taxed and regulated by the state. These casinos generate much more revenue and hire more labor from the general labor market than Indian casinos. The impact of corporate casino gaming on local employment is a major issue in the debate over legalized casino gaming. As a result, the issue has received careful study.7 This paper explores how corporate casinos affect employment in six Midwestern counties using various employment data and forecasting models. Changes in both household and payroll employment are examined to separate the effects on the residents and businesses in counties with casinos. Payroll employment changes may allude to possible interindustry substitution resulting from casino gaming. Also, both urban and rural “casino counties” are used in the analysis to
Impact of extracorporeal blood flow rate on blood pressure, pulse rate and cardiac output during haemodialysis.

BACKGROUND
If blood pressure (BP) falls during haemodialysis (HD) [intradialytic hypotension (IDH)] a common clinical practice is to reduce the extracorporeal blood flow rate (EBFR). Consequently the efficacy of the HD (Kt/V) is reduced. However, only very limited knowledge on the effect of reducing EBFR on BP exists and data are conflicting. The aim of this study was to evaluate the effect and the potential mechanism(s) involved by investigating the impact of changes in EBFR on BP, pulse rate (PR) and cardiac output (CO) in HD patients with arteriovenous-fistulas (AV-fistulas).


METHODS
We performed a randomized, crossover trial in 22 haemodynamically stable HD patients with AV-fistula. After a conventional HD session each patient was examined during EBFR of 200, 300 and 400 mL/min in random order. After 15 min when steady state was achieved CO, BP and PR were measured at each EFBR, respectively.


RESULTS
Mean (SD) age was 71 (11) years. Systolic BP was significantly higher at an EBFR of 200 mL/min as compared with 300 mL/min [133 (23) versus 128 (24) mmHg; P < 0.05], but not as compared with 400 mL/min [133 (23) versus 130 (19) mmHg; P = 0.20]. At EBFR of 200, 300 and 400 mL/min diastolic BP, mean arterial pressure, PR and CO remained unchanged.


CONCLUSION
Our study does not show any consistent trend in BP changes by a reduction in EBFR. Reduction in EBFR if BP falls during IDH is thus not supported. However, none of the patients experienced IDH. Further studies are required to evaluate the impact of changes in EBFR on BP during IDH.