LLukas22/scidocs huggingface dataset:
Effect of Helicobacter pylori infection on blood pressure: a community based cross sectional study.

For instance, the lack of declarations in New England Journal of Medicine editorials is not surprising as the journal (not always successfully) prohibits them being written by authors with financial ties. The Lancet’s in-house editorial team always writes the first editorial of each issue, signing it “The Lancet,” a style that makes it impossible to know whether contributing authors have competing interests. But subsequent editorials conform to the more common format of naming individual authors at the end of the article, making it possible to request, and thus publish, details of each author’s competing interests. The greater proportion of declarations in JAMA editorials may reflect the journal’s longstanding policy of requiring authors to sign documents declaring any financial competing interests. The proportion of declarations in BMJ papers was much greater in 1999 than 1996. This may reflect the journal’s adoption, in 1998, of Stelfox’s recommendations requiring authors to answer a series of short questions on their financial ties. Data in this study have been drawn from information published in journals, and not directly from what authors revealed to editors. There is potential for disparity here, but it is difficult to see why editors would decide against revealing competing interests that were disclosed to them, given what is clearly stated in their policies. Editors can learn much from examining the policies of other journals and adopting the features that seem conducive to disclosure. Research is needed to verify whether some of the authors who had not made a declaration did in fact have undeclared financial competing interests when they wrote their articles. It would also be useful to know the impact, if any, of competing interest statements on readers.
Lessons to be learnt in managing the breech presentation at term: an 11-year single-centre retrospective study.

BACKGROUND
The 2000 publication of the Term Breech Trial significantly impacted obstetric practice in Australia with a rapid increase in delivery of term breech singletons by caesarean section. More reassuring data from European centres who continued to offer vaginal breech deliveries to carefully selected women have led to a softening of international guidelines which now support an individualised approach to management. The application of this principle to an Australian population, particularly in the wake of such a major change in obstetric practice, has not previously been demonstrated.


AIM
To compare short-term neonatal and maternal morbidity for infants with a singleton breech presentation born after 37 weeks, according to planned mode of delivery.


MATERIALS AND METHODS
Eleven-year single-centre retrospective study with intention-to-treat analysis based on intended mode of delivery.


RESULTS
Two hundred and forty-three of 766 (31.7%) eligible women elected for planned vaginal breech delivery. The overall success rate in this group was 58%. Morbidity rates were low and compare favourably with similar international studies. However, there was a nonsignificant trend towards higher rates of short-term serious neonatal and maternal morbidity in the planned vaginal delivery group (1.6 vs 0.4%, P = 0.08 and 8.2 vs 4.8%, P = 0.06, respectively).


CONCLUSIONS
Attempted vaginal delivery for breech presentation remains an option in carefully selected women under strict obstetric protocols.
Role of genetic polymorphisms of the dopaminergic system in Parkinson's disease patients with impulse control disorders.

BACKGROUND
The mechanisms underlying the development of impulse control disorders (ICDs) like compulsive gambling, buying, sexual, and eating behaviors in Parkinson's disease (PD) are debated. We assessed whether allelic variants of dopamine D2 receptors (DRD2), catechol-O-methyltransferase (COMT) and dopamine transporter (DAT) were associated with the development of ICDs in PD.


METHOD
We enrolled 89 idiopathic PD patients (48 without ICDs and 41 with ICDs). All patients were screened with the Minnesota Impulsive Disorders Interview (MIDI) and fulfilled DSM-IV criteria for the ICD positive cohort. Differences in the frequency of the genotypes between ICDs and non-ICDs groups were assessed using the χ(2) test.


RESULTS
Genotyping was performed for variants of the DRD2 Taq1A (rs1800497), COMT Val(158)Met (rs4680), DAT1 (3' UTR 40bp VNTR). Variants of DRD2 Taq1A, COMT and DAT1 were not associated with the risk of developing ICDs.


CONCLUSION
In our study, there were no differences in the frequency of variant of DRD2 Taq1A, COMT and DAT1 between the two groups. Polymorphisms of dopaminergic genes do not play a relevant role in the development of ICD in PD suggesting that ICD originate from inability to filter inappropriate behaviors triggered by dopaminergic therapy.
Non-invasive cardiac stress testing before elective major non-cardiac surgery: population based cohort study

OBJECTIVE
To determine the association of non-invasive cardiac stress testing before elective intermediate to high risk non-cardiac surgery with survival and hospital stay.


DESIGN
Population based retrospective cohort study.


SETTING
Acute care hospitals in Ontario, Canada, between 1 April 1994 and 31 March 2004.


PARTICIPANTS
Patients aged 40 years or older who underwent specific elective intermediate to high risk non-cardiac surgical procedures.


INTERVENTIONS
Non-invasive cardiac stress testing performed within six months before surgery.


MAIN OUTCOME MEASURES
Postoperative one year survival and length of stay in hospital.


RESULTS
Of the 271 082 patients in the entire cohort, 23 991 (8.9%) underwent stress testing. After propensity score methods were used to reduce important differences between patients who did or did not undergo preoperative stress testing and assemble a matched cohort (n=46 120), testing was associated with improved one year survival (hazard ratio (HR) 0.92, 95% CI 0.86 to 0.99; P=0.03) and reduced mean hospital stay (difference -0.24 days, 95% CI -0.07 to -0.43; P<0.001). In an analysis of subgroups defined by Revised Cardiac Risk Index (RCRI) class, testing was associated with harm in low risk patients (RCRI 0 points: HR 1.35, 95% CI 1.05 to 1.74), but with benefit in patients who were at intermediate risk (RCRI 1-2 points: 0.92, 95% CI 0.85 to 0.99) or high risk (RCRI 3-6 points: 0.80, 95% CI 0.67 to 0.97).


CONCLUSIONS
Preoperative non-invasive cardiac stress testing is associated with improved one year survival and length of hospital stay in patients undergoing elective intermediate to high risk non-cardiac surgery. These benefits principally apply to patients with risk factors for perioperative cardiac complications.
The pediatric mandible: II. Management of traumatic injury or fracture.

LEARNING OBJECTIVES
After studying this article, the participant should be able to: 1. Describe the changing epidemiology of mandibular fractures in children and adolescents. 2. Discuss the appropriate use of internal fixation in the treatment of pediatric mandibular fractures. 3. Describe the difficulties posed by the deciduous dentition in the use of interdental wiring. 4. Understand reasons why techniques specific to adult fractures may not be applicable to the growing mandible. 5. Understand the etiology and epidemiology of pediatric mandibular fractures. 6. Understand the reasons for conservative (closed) versus aggressive (open) treatment of mandibular injury.


BACKGROUND
Fractures of the pediatric mandible are complicated by the anatomic complexity of the developing mandible, particularly by the presence of tooth buds and the eruption of deciduous and permanent teeth. Traditional methods of fracture reduction and fixation employed in adults have little applicability in the pediatric population.


METHODS
The authors describe the surgical techniques that have been used at their institution and those that can be used safely in the pediatric setting.


RESULTS
In most cases, "conservative" management is the preferred option, especially in the treatment of condylar fractures. In cases requiring surgical intervention, interdental wiring, drop wires in combination with circummandibular wires, and acrylic splints are suited well to specific phases of dental maturation.


CONCLUSION
Open reduction and internal fixation using monocortical screws and microplates or resorbable plates and screws are acceptable techniques in the pediatric patient, but they require special safeguards. Algorithms are presented to simplify management of these complicated injuries.
[Comparison between aquatic-biodanza and stretching for improving quality of life and pain in patients with fibromyalgia].

OBJECTIVE
To determine the level of improvement, as regards pain, impact on fibromyalgia and depression, achieved by patients with fibromyalgia by comparing aquatic biodanza and stretching exercises.


DESIGN
Randomised controlled trial with two intervention groups.


LOCATION
Five health centres (Almeria).


PATIENTS
A total of 82 fibromyalgia patients between 18 and 65 years old, diagnosed by American College of Rheumatology criteria, were included, with 12 patients declining to take part in the study. The 70 remaining patients were randomly assigned to two groups of 35 patients each: aquatic biodanza and stretching exercises. Those who did not attend in at least 14 sessions or changed their treatment during the studio were excluded. The final sample consisted of 19 patients in aquatic biodanza group and 20 in stretching group. The limitations of the study included, the open evaluation design and a sample size reduced by defaults.


MAIN MEASURES
The outcome measures were sociodemographic data, quality of life (Fibromyalgia Impact Questionnaire), pain (McGill-Melzack questionnaire; and Visual Analogue Scale), pressure algometry (Wagner FPI10 algometer) and depression (Beck Inventory). These were carried out before and after a 12-week therapy.


RESULTS
The mean age of the sample was 55.41 years. The mean period from diagnosis was 13.44 years. The sample consisted mainly of housewives. There were significant differences (P<.05) between groups, in pain (P<.01), fibromyalgia impact (P<.01), and depression (P<.04) after the treatment.


CONCLUSIONS
The biodanza aquatic exercises improve pain and quality of life in fibromyalgia patients.
More uniform Pd distribution in free-air balls of Pd-coated Cu bonding wire using movable flame-off electrode

The currently high price of gold wire has led to the development of bonding wire made from palladiumcoated-copper as a lower cost alternative. Increasing the uniformity of the Pd distribution in free-air balls, formed by melting the wire end with an electric spark, is of interest as it can influence the uniformity of process and reliability. To study this Pd distribution, free-air balls are made using four distinct electrical flame-off (spark) processes with short and long spark times from wire bonders with fixed and movable electrodes. Elemental analysis of the free-air ball surfaces reveal a higher Pd concentration on the movable electrode free-air balls than on the fixed electrode free-air balls. Elemental analysis of cross-sections show that the Pd distribution in free-air balls made with a fixed electrode has Pd trails flowing from the neck into the Cu ball center. Furthermore, microand nano-voids are observed to follow the Pd trails. In contrast, free-air balls made with a movable electrode exhibit less severe voiding and retain a uniform, thin Pd layer along the surface up to the tip of the free-air ball (shorter spark time). This can help to increase process consistency and reliability. 2014 Elsevier Ltd. All rights reserved.
Biochemistry of Cheese Ripening

Rennet-coagulated cheeses are ripened for periods ranging from about two weeks to two or more years depending on variety. During ripening, microbiological and biochemical changes occur that result in the development of the flavour and texture characteristic of the variety. Biochemical changes in cheese during ripening may be grouped into primary (lipolysis, proteolysis and metabolism of residual lactose and of lactate and citrate) or secondary (metabolism of fatty acids and of amino acids) events. Residual lactose is metabolized rapidly to lactate during the early stages of ripening. Lactate is an important precursor for a series of reactions including racemization, oxidation or microbial metabolism. Citrate metabolism is of great importance in certain varieties. Lipolysis in cheese is catalysed by lipases from various source, particularly the milk and cheese microflora, and, in varieties where this coagulant is used, by enzymes from rennet paste. Proteolysis is the most complex biochemical event that occurs during ripening and is catalysed by enzymes from residual coagulant, the milk (particularly plasmin) and proteinases and peptidases from lactic acid bacteria and, in certain varieties, other microorganisms that are encouraged to grow in or on the cheese. Secondary reactions lead to the production of volatile flavour compounds and pathways for the production of flavour compounds from fatty acids and amino acids are also reviewed.
Quantitative analysis of tumor-derived methylated RUNX3 sequences in the serum of gastric cancer patients.

PURPOSE AND EXPERIMENTAL DESIGN
Using real-time quantitative methylation-specific PCR (RTQ-MSP), methylated RUNX3 sequences were quantified and the fractional concentrations of circulating tumor DNA in serum were determined, along with peripheral blood cells collected preoperatively, intraoperatively and postoperatively from 65 patients with gastric cancer.


RESULTS
RTQ-MSP was sufficiently sensitive to detect RUNX3 methylation. Quantitative MSP data were expressed in terms of the methylation index, which was defined as the relative amount of methylated RUNX3 sequences divided by the concentration of methylated actin. High levels of methylated RUNX3 sequences were detected in the peripheral circulation of 29% (19 of 65) of the gastric cancer patients. The RUNX3 methylation index was concordant with cancer stage, histology, lymphatic and vascular invasion, and was more sensitive than carcinoembryonic antigen (CEA) as a biomarker. Twenty-nine percent (19 out of 65) of preoperative serum samples had methylated RUNX3 sequences, ranging from 5.2 to 1625955 (median quantity=43 m-index, sensitivity 95.5%, specificity 62.5%, AUC 0.8651). After surgical resection, the median RUNX3 methylation index in serum significantly decreased. These results demonstrate the clinical usefulness and effectiveness of peripheral blood RTQ-MSP for detecting and monitoring gastric cancer after treatment. Furthermore, 5 out of the 30 preoperative control samples of benign disease (cases of panperitonitis due to acute appendicitis or cholecystitis) showed transient RUNX3 methylation which decreased after the operation in accordance with recovery.


CONCLUSION
Quantification of epigenetic changes in serum RUNX3 methylation using RTQ-MSP is useful for the detection and monitoring of gastric cancer.
Developing effective e-recruiting websites: Insights for managers from marketers

0007-6813/$ see front matter © 200 doi:10.1016/j.bushor.2007.01.002 Abstract In recent years, the practice of using corporate websites to recruit job applicants has increased steadily. Despite this trend, however, studies show that approximately 75% of job seekers find the sites too complicated to use successfully [Brown, D. (2004). Unwanted online job seekers swamp HR staff. Canadian HR Reporter, 17(7), 1–2] and that more than 20% have rejected job opportunities based on poorly designed websites [Pastore, M. (2000, March 29). http://www.clickz.com/ showPage.html?page=330331]. To address this problem, this article joins Internet marketing and employee recruitment research to offer six development implications for creating an effective “e-recruitment” source on a corporate website. Based on a job marketing approach to the recruitment process and consumer behavior research on persuasive communication and decision making, we present considerations important to creating an online recruiting website that effectively influences the search decisions and behaviors of a target market of desired job candidates. © 2007 Kelley School of Business, Indiana University. All rights reserved.
Analysis and Modeling of Urban Land Cover Change in Setúbal and Sesimbra, Portugal

The expansion of cities entails the abandonment of forest and agricultural lands, and these lands‘ conversion into urban areas, which results in substantial impacts on ecosystems. Monitoring these changes and planning urban development can be successfully achieved using multitemporal remotely sensed data, spatial metrics, and modeling. In this paper, urban land use change analysis and modeling was carried out for the Concelhos of Setúbal and Sesimbra in Portugal. An existing land cover map for the year 1990, together with two derived land cover maps from multispectral satellite images for the years 2000 and 2006, were utilized using an object-oriented classification approach. Classification accuracy assessment revealed satisfactory results that fulfilled minimum standard accuracy levels. Urban land use dynamics, in terms of both patterns and quantities, were studied using selected landscape metrics and the Shannon Entropy index. Results show that urban areas increased by 91.11% between 1990 and 2006. In contrast, the change was only 6.34% between 2000 and 2006. The entropy value was 0.73 for both municipalities in 1990, indicating a high rate of urban sprawl in the area. In 2006, this value, for both Sesimbra and Setúbal, reached almost 0.90. This is demonstrative of a tendency toward intensive urban sprawl. Urban land use change for the year 2020 was modeled using a Cellular Automata based approach. The predictive power of the model was successfully validated using Kappa variations. Projected land cover changes show a growing tendency in urban land use, which might threaten areas that are currently reserved for natural parks and agricultural lands. OPEN ACCESS Remote Sens. 2010, 2 1550
Mechanical, thermomechanical, and thermal properties of polystyrene crosslinked with a multifunctional zirconium oxo cluster

Inorganic–organic hybrid materials were prepared by free radical polymerization of styrene in the presence of varying amounts of the cluster Zr6O4(OH)4 (methacrylate)12. Stepwise polymerization allowed the preparation of bubble- and crack-free, transparent bulk samples on a 30 g scale with dimensions required for mechanical testing. Small-angle X-ray scattering investigations and transmission electron micrographs revealed that the clusters formed randomly distributed aggregates of random size. Solvent uptake in swelling experiments was related to the cluster proportion. Storage moduli in the glassy state were slightly increased when compared with neat polystyrene, but pronounced plateau moduli were observed above the glass transition temperature, which correlated to the cluster proportion. Plateau moduli were used to calculate network parameters such as network density. Onset temperatures of thermal decomposition and the glass transition temperatures of the cluster-crosslinked polymers were higher than that of neat polystyrene. Thermal expansion coefficients were unaffected in the glassy state, but were gradually reduced above the glass transition temperature with increasing cluster proportion. Both the tensile moduli at room temperature and the yield points increased when polystyrene was doped with the cluster. The strain hardening moduli, as determined in compression tests at large deformations, increased linearly with the cluster proportion. © 2007 Wiley Periodicals, Inc. J Polym Sci Part B: Polym Phys 45: 2215–2231, 2007
Interactive Ground Water (IGW)

IGW is a software environment for real-time 2D and 3D groundwater modeling. The software functions as a ‘‘numerical laboratory’’ in which the modeler can freely explore: visually creating an aquifer of desired configurations and then immediately investigating and visualizing the groundwater system. IGW allows the modeler’s thought processes to progress naturally and intuitively with the information visualized, overlaid, and compared at the instant it is required for analysis, providing a real sense of continuous active exploration and engaged problem solving. 2005 Elsevier Ltd. All rights reserved.
A prospective evaluation of plastibell® circumcision in older children.

INTRODUCTION AND OBJECTIVE
Circumcision is one of the oldest surgical procedures and one of the most frequently performed worldwide. It can be done by many different techniques. This prospective series presents the results of Plastibell® circumcision in children older than 2 years of age, evaluating surgical duration, immediate and late complications, time for plastic device separation and factors associated with it.


MATERIALS AND METHODS
We prospectively analyzed 119 children submitted to Plastic Device Circumcision with Plastibell® by only one surgeon from December 2009 to June 2011. In all cases the surgery was done under general anesthesia associated with dorsal penile nerve block. Before surgery length of the penis and latero-lateral diameter of the glans were measured. Surgical duration, time of Plastibell® separation and use of analgesic medication in the post-operative period were evaluated. Patients were followed on days 15, 45, 90 and 120 after surgery.


RESULTS
Age at surgery varied from 2 to 12.5 (5.9 ± 2.9) years old. Mean surgical time was 3.7 ± 2.0 minutes (1.9 to 9 minutes). Time for plastic device separation ranged from 6 to 26 days (mean: 16 ± 4.2 days), being 14.8 days for children younger than 5 years of age and 17.4 days for those older than 5 years of age (p < 0.0001). The diameter of the Plastibell® does not interfered in separations time (p = 0,484). Late complications occurred in 32 (26.8%) subjects, being the great majority of low clinical significance, especially prepucial adherences, edema of the mucosa and discrete hypertrophy of the scar, all resolving with clinical treatment. One patient still using diaper had meatus stenosis and in one case the Plastibell® device stayed between the glans and the prepuce and needed to be removed manually.


CONCLUSIONS
Circumcision using a plastic device is a safe, quick and an easy technique with low complications, that when occur are of low clinical importance and of easy resolution. The mean time for the device to fall is shorter in children under 6 years of age and it is not influenced by the diameter of the device.
Children born extremely preterm show significant lower cognitive, language and motor function levels compared with children born at term, as measured by the Bayley-III at 2.5 years.

AIM
To assess developmental outcomes of children aged 2.5 years born extremely preterm.


METHODS
As a part of the population-based Extremely Preterm Infants in Sweden Study (EXPRESS), 399 children born before 27 weeks of gestation and 366 control children born at term were assessed with the Bayley Scales of Infant and Toddler Development, third edition (Bayley-III), assigning scores for cognition, receptive and expressive communication, fine and gross motor functions. Based on control group means, prevalences of developmental delay in the preterm group were calculated. Mean score differences between subtests constituting the overall Bayley-III indices were analysed within both groups.


RESULTS
After controlling for socio-demographic, child and assessment variables, analyses showed significantly lower performances of the preterm group compared with the control group on the Bayley-III subtests. Prevalence of moderate-severe delay was 10.8% in cognitive, 14.9% in receptive communication, 14.5% in expressive communication, 12.4% in fine motor and 7.0% in gross motor functions. Significant differences between performances on subtests included in the same indices were detected.


CONCLUSION
Extremely preterm children show significant lower cognitive, communicative and motor function levels at 2.5 years compared with children born at term. Bayley-III assessments permit the acquisition of nuanced information about development following extreme prematurity.