LLukas22/scidocs huggingface dataset:
Incidental gallbladder cancer at cholecystectomy: when should the surgeon be suspicious?

BACKGROUND
Preoperative predictors of incidental gallbladder cancer (iGBC) have been poorly defined despite the frequency with which cholecystectomy is performed. The objective of this study was to define the incidence of and consider risk factors for iGBC at cholecystectomy.


METHODS
The American College of Surgeons-National Surgical Quality Improvement Program (ACS-NSQIP) database (2005-2009) was used to identify all patients who underwent cholecystectomy (N = 91,260). Patients with an International Classification of Diseases, Ninth Revision, diagnosis of gallbladder malignancy who underwent a laparoscopic cholecystectomy (LC; n = 80,924) or open cholecystectomy (OC; n = 10,336) alone were included.


RESULTS
The incidence of iGBC was 0.19% (n = 170) for all cholecystectomy cases, but 0.05% at LC, 0.60% at LC converted to OC (P < 0.001 vs LC), and 1.13% at OC (P < 0.001 vs others). Patients undergoing OC were 17.3 times more likely to have iGBC than LC patients. Age 65 years or older, Asian or African American race, ASA (American Society of Anesthesiologists) class 3 or more, diabetes mellitus, hypertension, weight loss more than 10%, alkaline phosphatase levels 120 units/L or more, and albumin levels 3.6 g/dL or less were associated with iGBC. Multiple logistic regression identified having an OC, age 65 years or older, Asian or African American race, an elevated alkaline phosphatase level, and female sex as independent risk factors. Patients with 1, 2, 3, and 4 of these factors had a 6.3-, 16.7-, 30.0-, and 47.4-fold risk of iGBC, respectively, from a zero-risk factor baseline of 0.03%.


CONCLUSIONS
Surgeons' suspicion for GBC should be heightened when they are performing or converting from LC to OC and when patients are older, Asian or African American, female, and have an elevated alkaline phosphatase level.
Brand Personality ’ s Influence on the Purchase Intention : A Mobile Marketing Case

This study underlines the value of the brand personality and its influence on consumer’s decision making, through relational variables. An empirical study, in which 380 participants have received an SMS ad, confirms that brand personality does actually influence brand trust, brand attachment and brand commitment. The levels of brand sensitivity and involvement have also an impact on the brand personality and on its related variables.
Comments on the scalar-tensor representation of nonlocally corrected gravity

The scalar-tensor representation of some simple nonlocally modified Einstein models is considered. Some special solutions of the vacuum background equations were obtained that indicate nonequivalence of the models under consideration in the scalar-tensor description and in the initial one.
Poor mental health in Ghana: who is at risk?

BACKGROUND
Poor mental health is a leading cause of disability worldwide with considerable negative impacts, particularly in low-income countries. Nevertheless, empirical evidence on its national prevalence in low-income countries, particularly in Africa, is limited. Additionally, researchers and policy makers are now calling for empirical investigations of the association between empowerment and poor mental health among women. We therefore sought to estimate the national prevalence of poor mental health in Ghana, explore its correlates on a national level, and examine associations between empowerment and poor mental health among women.


METHODS
We conducted a cross-sectional analysis using data from a nationally representative survey conducted in Ghana in 2009-2010. Interviews were conducted face-to-face with participants (N = 9,524 for overall sample; n = 3,007 for women in relationships). We used the Kessler Psychological Distress Scale (K10) to measure psychological distress and assessed women's attitudes about their roles in decision-making, attitudes towards intimate partner violence, partner control, and partner abuse. We used weighted multivariable multinomial regression models to determine the factors independently associated with experiencing psychological distress for our overall sample and for women in relationships.


RESULTS
Overall, 18.7% of the sample reported either moderate (11.7%) or severe (7.0%) psychological distress. The prevalence of psychological distress was higher among women than men. Overall, the prevalence of psychological distress differed by gender, marital status, education, wealth, region, health and religion, but not by age or urban/rural location. Women who reported having experienced physical abuse, increased partner control, and who were more accepting of women's disempowerment had greater likelihoods of psychological distress (P-values < 0.05).


CONCLUSIONS
Psychological distress is substantial among both men and women in Ghana, with nearly 20% having moderate or severe psychological distress, an estimate higher than those found among South African (16%) or Australian (11%) adults. Women who are disempowered in the context of intimate relationships may be particularly vulnerable to psychological distress. Results identify populations to be targeted by interventions aiming to improve mental health.
Face-to-face collaborative learning supported by mobile phones

The use of handheld computers in educational contexts has increased considerably in recent years and their value as a teaching tool has been confirmed by many positive experiences, particular within collaborative learning systems (MCSCL). The cost of the devices has hindered widespread use in schools, however, and cell phones have emerged as an attractive alternative. To test the functionality of cell phones as a platform for collaborative educational activities, the authors adapted an existing PDA application for use on cell phones equipped with Wi-Fi. This article examines the problems of developing applications for this alternative technology and reports on a usability analysis of a collaborative classroom activity for teaching physics. The results confirm the viability of the cell phone platform, with due account taken of the device’s processing, network and interface limitations. With an appropriate design, users quickly master the technology, though a certain decline in efficiency relative to PDAs was observed. This work was partially funded by FONDECYT-CONICYT grant No. 1080100
School-based mindfulness instruction for urban male youth: a small randomized controlled trial.

OBJECTIVES
Mindfulness-based stress reduction (MBSR) has been shown to improve mental health and reduce stress in a variety of adult populations. Here, we explore the effects of a school-based MBSR program for young urban males.


PARTICIPANTS AND METHODS
In fall 2009, 7th and 8th graders at a small school for low-income urban boys were randomly assigned to 12-session programs of MBSR or health education (Healthy Topics-HT). Data were collected at baseline, post-program, and three-month follow-up on psychological functioning; sleep; and salivary cortisol, a physiologic measure of stress.


RESULTS
Forty-one (22 MBSR and 19 HT) of the 42 eligible boys participated, of whom 95% were African American, with a mean age of 12.5 years. Following the programs, MBSR boys had less anxiety (p=0.01), less rumination (p=0.02), and showed a trend for less negative coping (p=0.06) than HT boys. Comparing baseline with post-program, cortisol levels increased during the academic terms for HT participants at a trend level (p=0.07) but remained constant for MBSR participants (p=0.33).


CONCLUSIONS
In this study, MBSR participants showed less anxiety, improved coping, and a possible attenuation of cortisol response to academic stress, when compared with HT participants. These results suggest that MBSR improves psychological functioning among urban male youth.
Cutaneous Sinus Tracts of Odontogenic Origin: Two Case Reports.

BACKGROUND
Cutaneous odontogenic fistulas or sinus tracts are frequently misdiagnosed and incorrectly treated, leading to unnecessary procedures and patient suffering. An understanding of the draining of cutaneous sinus tracts will lead to more appropriate treatment. Most cases respond to conservative, nonsurgical root canal therapy. Our objective is to report 2 cases of cutaneous sinus tract secondary to chronic periapical dental infection that were recently observed at our hospital.


METHODS
We present 2 cases of recurrent suppurative facial lesions that were initially misdiagnosed and treated with oral antibiotics without response.


RESULTS
Clinical findings included palpable facial nodules with drainage, palpable intraoral cords, and poor dentition with gingivitis; radiologic examination showed a periapical disease process consistent with dental sinus tracts. Both of the cases were referred to the maxillofacial department, where the cyst and nonrestorable teeth were extracted.


CONCLUSION
Because patients with cutaneous facial sinus tracts of dental origin often do not have obvious dental symptoms, a possible dental etiology may be overlooked. If dental origin is suspected, the diagnosis is easily confirmed by dental examination and dental roentgenograms of the involved area. Early correct diagnosis, based on radiologic evidence of a periapical root infection and treatment of these lesions can help prevent unnecessary and ineffective antibiotic therapy or surgical treatment, reducing the possibility of further complications such as sepsis and osteomyelitis.
OVERVIEW OF THE CURRENT ACTIVITIES OF THE EUROPEAN EGS SOULTZ PROJECT : FROM EXPLORATION TO ELECTRICITY PRODUCTION

This paper reports a multinational approach to develop an Enhanced Geothermal System reservoir (EGS) in Europe. The pilot site is located at the French-German border in Soultz-sous-Forêts, France. Over two decades research and development have been carried out with French, German and Swiss governmental and European funding. The on-going Soultz project is now very close to the end of the pilot plant phase (2009). Then, a geothermal power plant constructing phase started in 2007 with the building of an ORC (Organic Rankine Cycle) plant having a net power capacity of 1,5MWe. Surface equipments (turbine, air cooling system, heat exchanger) as well as two different types of downhole pumps were installed respectively on surface and in the production wells. Finally, we present the main milestones about the EGS reservoir and the ongoing activities about this experimental power plant.
[Effects of a home-based exercise program for patients with stomach cancer receiving oral chemotherapy after surgery].

PURPOSE
The purpose of this study was to identify the effects of a home based exercise program for patients with stomach cancer who were undergoing oral chemotherapy.


METHODS
The home-based exercise program was developed from the study findings of Winningham (1990) and data from the Korea Athletic Promotion Association (2007). The home-based exercise program consisted of 8 weeks of individual exercise education and exercise adherence strategy. Participants were 24 patients with stomach cancer who were undergoing oral chemotherapy following surgery in 2007 or 2008 at a university hospital in Seoul. Patients were randomly assigned to either the experimental group (11) or control group (13). The effects of the home-based exercise program were measured by level of cancer related fatigue, NK cell ratio, anxiety, and quality of life. Data were analyzed using SPSS/WIN 13.0 version.


RESULTS
The degree of cancer related fatigue and anxiety in the experimental group decreased compared to the control group. The NK cell ratio and the degree of quality of life of experimental group increased while that of the control group decreased.


CONCLUSION
This study result indicate the importance of exercise and provide empirical evidence for continuation of safe exercise for patients with cancer during their chemotherapy.
Question Answering in TREC

Traditional text retrieval systems return a ranked list of documents in response to a user's request. While a ranked list of documents can be an appropriate response for the user, frequently it is not. Usually it would be better for the system to provide the answer itself instead of requiring the user to search for the answer in a set of documents. The Text REtrieval Conference (TREC) is sponsoring a question answering "track" to foster research on the problem of retrieving answers rather than document lists.TREC is a workshop series sponsored by the National Institute of Standards and Technology and the U.S. Department of Defense [7]. The purpose of the conference series is to encourage research on text retrieval for realistic applications by providing large test collections, uniform scoring procedures, and a forum for organizations interested in comparing results. The conference has focused primarily on the traditional IR problem of retrieving a ranked list of documents in response to a statement of information need, but has also included other tasks, called tracks, that focus on new areas or particularly difficult aspects of information retrieval. A question answering track was introduced in TREC-8 1999. The track has generated wide-spread interest in the QA problem [2, 3, 4], and has documented significant improvements in question answering system effectiveness in its two-year history.This paper provides a brief summary of the findings of the TREC question answering track to date and discusses the future directions of the track. The paper is extracted from a fuller description of the track given in "The TREC Question Answering Track" [8]. Complete details about the TREC question answering track can be found in the TREC proceedings.
Cave deposits and sedimentary processes in Cova des Pas de Vallgornera (Mallorca, Western Mediterranean)

In the above mentioned papers different types of sediments and genetic processes have been described as being the dominant mechanisms in producing the allochthonous in fillings that were carried into the caves mainly through surface entrances. The most frequent types are reddish-brown fine sediments mostly transported into the cave by surface runoff as in the case of Cova des Coll or Cova Genovesa (Gràcia et al., 2003, 2005), or by eolian processes as in the case of Cova de s’Ònix (Ginés et al., 2007), Cova de sa Font (Egozcue, 1971), Cova de sa Bassa Blanca (Ginés & Ginés, 1974), among others, or mixed eolian and runoff deposits as is the case of Galeria del Tragus in Cova des Pas de Vallgornera (Fornós et al., 2010). Autogenic processes have also been suggested for Cova de sa Gleda (Gràcia et al., 2007) and in the PirataPont-Piqueta system (Gràcia et al., 2006; Fornós et INTRODUCTION
A randomized, double-blind, placebo-controlled study of the efficacy and safety of vortioxetine 10 mg and 20 mg in adults with major depressive disorder.

CONTEXT
Vortioxetine (Lu AA21004) is an antidepressant with a mechanism of action thought to be related to a combination of 2 pharmacologic actions: direct modulation of several receptors and inhibition of the serotonin transporter.


OBJECTIVE
To evaluate the efficacy of vortioxetine 10 and 20 mg once daily in outpatients with major depressive disorder.


DESIGN, SETTING, AND PARTICIPANTS
This 8-week, multicenter, randomized, double-blind, placebo-controlled, parallel-group study was conducted from July 2010 to January 2012 among adults with a primary diagnosis of recurrent major depressive disorder (DSM-IV-TR).


INTERVENTION
Eligible subjects were randomized in 1:1:1 ratio to 1 of 3 treatment arms: vortioxetine 10 mg, vortioxetine 20 mg, or placebo once daily for 8 weeks. Subjects who completed the 8-week trial entered a 2-week blinded discontinuation period to assess potential discontinuation symptoms.


MAIN OUTCOME MEASURE
The primary endpoint was the least squares mean change in Montgomery-Asberg Depression Rating Scale (MADRS) total score from baseline. Key secondary outcomes were analyzed in the following prespecified sequential order: MADRS response (≥ 50% decrease from baseline in total score), Clinical Global Impressions-Improvement score, change from baseline in MADRS total score in subjects with baseline Hamilton Anxiety Rating Scale score ≥ 20, MADRS remission (total score ≤ 10), and change from baseline in Sheehan Disability Scale total score (all at week 8).


RESULTS
A total of 462 subjects were randomized to placebo (n = 157), vortioxetine 10 mg (n = 155), and vortioxetine 20 mg (n = 150). Mean (SE) reductions from baseline in MADRS total score (week 8) were -10.77 (± 0.807), -12.96 (± 0.832), and -14.41 (± 0.845) for the placebo, vortioxetine 10 mg (P = .058 vs placebo), and vortioxetine 20 mg (P = .002 vs placebo) groups. MADRS response/remission was achieved in 28.4%/14.2%, 33.8%/21.4%, and 39.2%/22.3% of subjects, respectively, in the 3 groups. Only MADRS response for vortioxetine 20 mg significantly separated from placebo (P = .044). Treatment was well tolerated, with the most frequently reported adverse events consisting of nausea, headache, diarrhea, and dizziness.


CONCLUSIONS
Vortioxetine 20 mg significantly reduced MADRS total score at 8 weeks in this study population. Overall, vortioxetine was well tolerated in this study.


TRIAL REGISTRATION
ClinicalTrials.gov identifier: NCT01163266.
Behavioural interventions for HIV positive prevention in developing countries: a systematic review and meta-analysis.

OBJECTIVE
To assess the evidence for a differential effect of positive prevention interventions among individuals infected and not infected with human immunodeficiency virus (HIV) in developing countries, and to assess the effectiveness of interventions targeted specifically at people living with HIV.


METHODS
We conducted a systematic review and meta-analysis of papers on positive prevention behavioural interventions in developing countries published between January 1990 and December 2006. Standardized methods of searching and data abstraction were used. Pooled effect sizes were calculated using random effects models.


FINDINGS
Nineteen studies met the inclusion criteria. In meta-analysis, behavioural interventions had a stronger impact on condom use among HIV-positive (HIV+) individuals (odds ratio, OR: 3.61; 95% confidence interval, CI: 2.61-4.99) than among HIV-negative individuals (OR: 1.32; 95% CI: 0.77-2.26). Interventions specifically targeting HIV+ individuals also showed a positive effect on condom use (OR: 7.84; 95% CI: 2.82-21.79), which was particularly strong among HIV-serodiscordant couples (OR: 67.38; 95% CI: 36.17-125.52). Interventions included in this review were limited both in scope (most were HIV counselling and testing interventions) and in target populations (most were conducted among heterosexual adults or HIV-serodiscordant couples).


CONCLUSION
Current evidence suggests that interventions targeting people living with HIV in developing countries increase condom use, especially among HIV-serodiscordant couples. Comprehensive positive prevention interventions targeting diverse populations and covering a range of intervention modalities are needed to keep HIV+ individuals physically and mentally healthy, prevent transmission of HIV infection and increase the agency and involvement of people living with HIV.
The impact of cost, technology acceptance and employees' satisfaction on the effectiveness of the electronic customer relationship management systems

Internet technology enables companies to capture new customers, track their performances and online behavior, and customize communications, products, services, and prices. Customer relationship management (CRM) is an important concept to maintain competitiveness at e-commerce. The issue of electronic customer relationship management (E-CRM) has increasingly become the identification of the success of the CRM implementation. The E-CRM has emerged as one of the most prominent information system that enables organizations to contact customers and collect, store and analyze customer data in order to provide a comprehensive view of their customers. Organization can obtain competitive advantages from increase effectiveness of the E-CRM. This research proposes determining the effective factors (cost, technology acceptance and employees’ satisfaction) for the effectiveness of the E-CRM. The structural equation modeling technique was used to evaluate the causal model and to examine the reliability and validity of the measurement model. The results of gathered data from 210 employees of the East Azerbaijan Tax Administration in iran is indicated that the impact of the technology acceptance on organization performance begins with infrastructure capability, ease of use, and E-learning systems, and the complementarity between these factors positively influences the effectiveness of the E-CRM. The results also indicated that the customer costs positively affects on the customer relationship performance, which consequently leads to improvements of the effectiveness of the E-CRM in organization. Our findings show that each of cost, technology acceptance and satisfaction employee plays an important role toward in effectiveness of
Cross-situational coping with peer and family stressors in adolescent offspring of depressed parents.

Offspring of depressed parents are faced with significant interpersonal stress both within their families and in peer relationships. The present study examined parent and self-reports of adolescents' coping in response to family and peer stressors in 73 adolescent children of parents with a history of depression. Correlational analyses indicated that adolescents were moderately consistent in the coping strategies used with peer stress and family stress. Mean levels of coping were similar across situations, as adolescents reported greater use of secondary control coping (i.e., acceptance, distraction) than primary control coping (i.e., problem solving, emotional expression) or disengagement coping (i.e., avoidance) with both types of stress. Regression analyses indicated that fewer symptoms of self-reported anxiety/depression and aggression were related to using secondary control coping strategies in response to family stress and primary control coping in response to peer stress. Implications for understanding the characteristics of effective coping with stress related to living with a depressed parent are highlighted.
Approximate graph edit distance computation by means of bipartite graph matching

In recent years, the use of graph based object representation has gained popularity. Simultaneously, graph edit distance emerged as a powerful and flexible graph matching paradigm that can be used to address different tasks in pattern recognition, machine learning, and data mining. The key advantages of graph edit distance are its high degree of flexibility, which makes it applicable to any type of graph, and the fact that one can integrate domain specific knowledge about object similarity by means of specific edit cost functions. Its computational complexity, however, is exponential in the number of nodes of the involved graphs. Consequently, exact graph edit distance is feasible for graphs of rather small size only. In the present paper we introduce a novel algorithm which allows us to approximately, or suboptimally, compute edit distance in a substantially faster way. The proposed algorithm considers only local, rather than global, edge structure during the optimization process. In experiments on different datasets we demonstrate a substantial speed-up of our proposed method over two reference systems. Moreover, it is emprically verified that the accuracy of the suboptimal distance remains sufficiently accurate for various pattern recognition applications. 2008 Elsevier B.V. All rights reserved.