LLukas22/scidocs huggingface dataset:
A randomized, multicenter, single-blinded trial comparing paclitaxel-coated balloon angioplasty with plain balloon angioplasty in drug-eluting stent restenosis: the PEPCAD-DES study.

OBJECTIVES
This study sought to define the impact of paclitaxel-coated balloon angioplasty for treatment of drug-eluting stent restenosis compared with uncoated balloon angioplasty alone.


BACKGROUND
Drug-coated balloon angioplasty is associated with favorable results for treatment of bare-metal stent restenosis.


METHODS
In this prospective, single-blind, multicenter, randomized trial, the authors randomly assigned 110 patients with drug-eluting stent restenoses located in a native coronary artery to paclitaxel-coated balloon angioplasty or uncoated balloon angioplasty. Dual antiplatelet therapy was prescribed for 6 months. Angiographic follow-up was scheduled at 6 months. The primary endpoint was late lumen loss. The secondary clinical endpoint was a composite of cardiac death, myocardial infarction attributed to the target vessel, or target lesion revascularization.


RESULTS
There was no difference in patient baseline characteristics or procedural results. Angiographic follow-up rate was 91%. Treatment with paclitaxel-coated balloon was superior to balloon angioplasty alone with a late loss of 0.43 ± 0.61 mm versus 1.03 ± 0.77 mm (p < 0.001), respectively. Restenosis rate was significantly reduced from 58.1% to 17.2% (p < 0.001), and the composite clinical endpoint was significantly reduced from 50.0% to 16.7% (p < 0.001), respectively.


CONCLUSIONS
Paclitaxel-coated balloon angioplasty is superior to balloon angioplasty alone for treatment of drug-eluting stent restenosis. (PEPCAD DES-Treatment of DES-In-Stent Restenosis With SeQuent® Please Paclitaxel Eluting PTCA Catheter [PEPCAD-DES]; NCT00998439).
The effects of therapeutic taping on gross motor function in children with cerebral palsy.

PURPOSE
Therapeutic taping to address dysfunctional sitting control in children with cerebral palsy (CP) was investigated in this study.


METHODS
Eighteen children with quadriplegic CP, Gross Motor Function Classification System for Cerebral Palsy levels IV (n = 9) and V (n = 9) participated in the 12-week program. Subjects were assigned randomly to one of two groups: therapeutic taping + physical therapy or physical therapy only. Therapeutic taping was applied for periods of up to 72 hours over the paraspinal region. The effects were assessed with the Gross Motor Function Measure (GMFM-88) at baseline, six weeks, and 12 weeks. A factorial analysis of variance was used to examine group differences over time.


RESULTS
No significant differences were found for the GMFM-88 scores between groups over time.


CONCLUSION
Therapeutic taping does not evoke a positive functional change in the seated postural control of children with quadriplegic cerebral palsy. Subjective observation, however, suggested that one child with athetosis benefited from therapeutic taping over the paraspinal region.
The so-called stunning of thyroid tissue.

UNLABELLED
When thyroid tissues exhibited concentrations of therapeutic (131)I that appeared to be less than that predicted by data from the preceding diagnostic (131)I, the phenomenon was called stunning. We hypothesized that stunning arose from the early effects of the therapeutic dose of (131)I and that the initial uptake of (131)I, observed within the first day, was not impaired by the diagnostic dose.


METHODS
The hypothesis was tested by 2 types of studies. In each type, the fractional concentrations of (131)I in residual neck thyroid tissues of patients with papillary thyroid carcinoma were quantified. In the first study, fractional concentrations of diagnostic and therapeutic (131)I were measured at 2 d, a time when stunning has been observed, and expressed as ratios of radioactivity: therapeutic/diagnostic (Rx/Dx). Three different doses of diagnostic (131)I were prescribed to assess a dose response. In the second study, patients were prospectively recruited and tested to record disappearances of radioactivity from thyroid tissues. Diagnostic doses were 1.0 mCi (37 MBq) in all; therapeutic doses were 150 and 30 mCi (5,550 and 1,110 MBq), each to half of the patients. The disappearance curves were extrapolated to the period between 0 and 1 d, an interval when maximum uptake of ingested (131)I would be expected. The fractional concentrations of (131)I at 2 d and at 0-1 d were compared in terms of Rx/Dx ratios to assess changes at each time point.


RESULTS
In the first study, after diagnostic doses of 2, 1, and 0.5 mCi (74, 37, and 18.5 MBq), mean 2-d Rx/Dx values in 24, 29, and 17 patients were 0.35, 0.50, and 0.46 (P = 0.087). Of all patients, 74% exhibited Rx/Dx <0.6. In the second study, 6 of 10 patients exhibited disappearance curves of (131)I in which Rx/Dx was <0.6 at 2 d; 5 of the 6 had Rx/Dx values >0.97 at the 0- to 1-d point. In 1 patient the Rx/Dx was 0.54 at 2 d and 0.66 at the earlier time point. The other 4 patients had disappearance curves in which Rx/Dx values were >1.0 throughout or were above 0.6 and did not greatly change.


CONCLUSION
Two days after the administration of (131)I, the mean fractional concentration of radioactivity in thyroid tissues after a therapeutic dose is <60% of the diagnostic dose in most patients, but no correlation of Rx/Dx with the mCi in the diagnostic dose was seen. In 5 of 6 patients in whom the Rx/Dx at 2 d was <0.6, the maximum fractional concentrations of therapeutic and diagnostic (131)I (i.e., the tissue uptakes during the first day) were similar; this pattern was most apparent after therapies with 150 mCi. These results support the hypothesis that "stunning" of thyroid tissues, often observable by 2 d, is primarily the consequence of early destructive effects from therapeutic (131)I.
Equivalent circuit model of the IC-Stripline coupling to IC package

As the operating frequency of integrated circuit (IC) is rapidly increased, the importance of electromagnetic compatibility (EMC) performance test in the design stage of IC development process is becoming more significant. The new EMC test method, IC-Stripline enables fast and accurate EMC test with smaller form factor and lower cost compared with transverse electromagnetic (TEM) cell which is the most widely used for radiated electromagnetic interference test at the moment. This paper presents the equivalent lumped-element circuit model to capture capacitive and inductive coupling between open version of IC-Stripline and an IC package. Also, the equations to calculate the circuit components with geometrical structure of IC-Stripline are proposed. The S-parameter results from presented circuit models are compared against those obtained by 3D EM solver. The presented models are very accurate up to 3 GHz which is the upper limit of effective frequency range of IC-Stripline described in IEC standards [1], [2]. Therefore, the proposed IC-Stripline models can be effectively used to predict radiated emission and immunity of ICs using circuit level simulation tools.
Primary repair of bilateral cleft lip and nasal deformity.

LEARNING OBJECTIVES
After studying this article, the participant should be able to: 1. List five principles that guide synchronous repair of bilateral complete cleft lip and nasal deformity. 2. Explain how different growth rates for the principal nasolabial features are applied during primary repair. 3. Describe two approaches for positioning the alar cartilages to form the columella. 4. Discuss the influences on referral patterns for a newborn with bilateral cleft lip. --Traditional repair of bilateral cleft lip focused on labial closure but accentuated the nasal deformities, which were addressed later. By the end of the past century, single-staged labial closure had replaced the old multistaged procedures and the technical emphasis had begun to shift from secondary to primary nasal correction. Now, presurgical maxillary orthopedics sets the bony foundation for synchronous nasolabial repair and for closure of the alveolar clefts. The study of normal nasolabial growth and the typical stigmata of the conventional methods provides the necessary foreknowledge to guide surgical sculpture in three dimensions and to anticipate the fourth dimension. The convergence of several forces are changing referral lines for children born with bilateral cleft lip. These include affirmation of centers of excellence, surgeons' self-regulation, prenatal diagnosis, economics of health-care delivery, and increasing parental sophistication. These pressures are not necessarily in conflict. Care by a subspecialized plastic surgeon and experienced team is in the best interests of the child and the third-party payer.
A theoretical model of intentional social action in online social networks

a r t i c l e i n f o Keywords: We-intention Social influence Social identity Subjective norm Group norm Online social networks IS adoption IS continuance Online social networks (Facebook, MySpace, LinkedIn and the like) have become truly significant new phenomena in human communication and interaction patterns and may have a profound impact in the way people communicate and connect with each other. In this study, the decision to use an online social network is conceptualized as intentional social action and the relative impact of the three modes of social influence processes (compliance, internalization, and identification) on intentional social action to use (collective intention) is examined. An empirical study of Facebook users (n = 389) found that collective intention to use a social networking site is determined by both subjective norm and social identity. Further, social identity is found to be a second-order latent construct comprised of cognitive, evaluative, and affective (first-order) components. Implications for research and practice are discussed. The growth and public popularity of Web 2.0 applications have created a new world of collaboration and communication. More than a billion individuals around the world are connected. They support themselves through wikis, podcasts, discussion posts, comments, and instant messaging. New generation online social networks (a Web 2.0 application), as enabled by the widespread diffusion of high-speed Internet, have even emerged as a mainstream communication and interaction modality with ever-increasing significance in the information society in which we live today. Facebook, MySpace, LinkedIn, and other similar online social networking sites provide online spaces where individuals can create a profile and connect that profile to others to create a personal network. In online social networking sites, social interaction and connection is the objective. These online social networking sites give everyone a place to share their personal stories, in words, pictures, and videos with their friends. They also connect people with friends and others who work, study, and live around them. They help people learn more about events, parties, and other social functions. Participation and continuance in online social networks represents a new social phenomenon that depends largely on the interactions with other users in a personal network. While recent information systems (IS) studies have started to address the issue of online social networks [15,20,21], these studies basically adopted the classical individual-based models to investigate the use of this new or complex communication and interaction phenomena. The classical individual-based models …
School Start Times, Sleep, Behavioral, Health, and Academic Outcomes: A Review of the Literature.

BACKGROUND
Insufficient sleep in adolescents has been shown to be associated with a wide variety of adverse outcomes, from poor mental and physical health to behavioral problems and lower academic grades. However, most high school students do not get sufficient sleep. Delaying school start times for adolescents has been proposed as a policy change to address insufficient sleep in this population and potentially to improve students' academic performance, reduce engagement in risk behaviors, and improve health.


METHODS
This article reviews 38 reports examining the association between school start times, sleep, and other outcomes among adolescent students.


RESULTS
Most studies reviewed provide evidence that delaying school start time increases weeknight sleep duration among adolescents, primarily by delaying rise times. Most of the studies saw a significant increase in sleep duration even with relatively small delays in start times of half an hour or so. Later start times also generally correspond to improved attendance, less tardiness, less falling asleep in class, better grades, and fewer motor vehicle crashes.


CONCLUSIONS
Although additional research is necessary, research results that are already available should be disseminated to stakeholders to enable the development of evidence-based school policies.
Moderate Load Eccentric Exercise; A Distinct Novel Training Modality

Over the last 20 years a number of studies have been published using progressive eccentric exercise protocols on motorized ergometers or similar devices that allow for controlled application of eccentric loads. Exercise protocols ramp eccentric loads over an initial 3 weeks period in order to prevent muscle damage and delayed onset muscle soreness. Final training loads reach 400-500 W in rehabilitative settings and over 1200 W in elite athletes. Training is typically carried out three times per week for durations of 20-30 min. This type of training has been characterizes as moderate load eccentric exercise. It has also been denoted RENEW (Resistance Exercise via Negative Eccentric Work by LaStayo et al., 2014). It is distinct from plyometric exercises (i.e., drop jumps) that impose muscle loads of several thousand Watts on muscles and tendons. It is also distinct from eccentric overload training whereby loads in a conventional strength training setting are increased in the eccentric phase of the movement to match concentric loads. Moderate load eccentric exercise (or RENEW) has been shown to be similarly effective as conventional strength training in increasing muscle strength and muscle volume. However, as carried out at higher angular velocities of joint movement, it reduces joint loads. A hallmark of moderate load eccentric exercise is the fact that the energy requirements are typically 4-fold smaller than in concentric exercise of the same load. This makes moderate load eccentric exercise training the tool of choice in medical conditions with limitations in muscle energy supply. The use and effectiveness of moderate load eccentric exercise has been demonstrated mostly in small scale studies for cardiorespiratory conditions, sarcopenia of old age, cancer, diabetes type 2, and neurological conditions. It has also been used effectively in the prevention and rehabilitation of injuries of the locomotor system in particular the rehabilitation after anterior cruciate ligament surgery.
Genetic association of miRNA-146a with systemic lupus erythematosus in Europeans through decreased expression of the gene

A recent genome-wide association study revealed a variant (rs2431697) in an intergenic region, between the pituitary tumor-transforming 1 (PTTG1) and microRNA (miR-146a) genes, associated with systemic lupus erythematosus (SLE) susceptibility. Here, we analyzed with a case–control design this variant and other candidate polymorphisms in this region together with expression analysis in order to clarify to which gene this association is related. The single-nucleotide polymorphisms (SNPs) rs2431697, rs2910164 and rs2277920 were genotyped by TaqMan assays in 1324 SLE patients and 1453 healthy controls of European ancestry. Genetic association was statistically analyzed using Unphased. Gene expression of PTTG1, the miRNAs miR-3142 and primary and mature forms of miR-146a in peripheral blood mononuclear cells (PBMCs) were assessed by quantitative real-time PCR. Of the three variants analyzed, only rs2431697 was genetically associated with SLE in Europeans. Gene expression analysis revealed that this SNP was not associated with PTTG1 expression levels, but with the microRNA-146a, where the risk allele correlates with lower expression of the miRNA. We replicated the genetic association of rs2341697 with SLE in a case–control study in Europeans and demonstrated that the risk allele of this SNP correlates with a downregulation of the miRNA 146a, potentially important in SLE etiology.
Economic integration in China : Politics and culture

Herrmann-Pillath, Carsten, Libman, Alexander, and Yu, Xiaofan—Economic integration in China: Politics and culture The aim of the paper is to explicitly disentangle the role of political and cultural boundaries as factors of fragmentation of economies within large countries. On the one hand, local protectionism plays a substantial role in many federations and decentralized states. On the other hand, if the country exhibits high level of cultural heterogeneity, it may also contribute to the economic fragmentation; however, this topic has received significantly less attention in the literature. This paper looks at the case of China and proxies the cultural heterogeneity by the heterogeneity of local dialects. It shows that the effect of politics clearly dominates that of culture: while provincial borders seem to have a strong influence disrupting economic ties, economic linkages across provinces, even if the regions fall into the same linguistic zone, are rather weak and, on the contrary, linguistic differences within provinces do not prevent economic integration. For some language zones we do, however, find a stronger effect on economic integration. Journal of Comparative Economics 42 (2) (2014) 470–492. Frankfurt School of Finance and Management, Germany; Russian Academy of Sciences, Russia. 2013 Association for Comparative Economic Studies Published by Elsevier Inc. All rights reserved.
Text mining for market prediction: A systematic review

The quality of the interpretation of the sentiment in the online buzz in the social media and the online news can determine the predictability of financial markets and cause huge gains or losses. That is why a number of researchers have turned their full attention to the different aspects of this problem lately. However, there is no well-rounded theoretical and technical framework for approaching the problem to the best of our knowledge. We believe the existing lack of such clarity on the topic is due to its interdisciplinary nature that involves at its core both behavioral-economic topics as well as artificial intelligence. We dive deeper into the interdisciplinary nature and contribute to the formation of a clear frame of discussion. We review the related works that are about market prediction based on onlinetext-mining and produce a picture of the generic components that they all have. We, furthermore, compare each system with the rest and identify their main differentiating factors. Our comparative analysis of the systems expands onto the theoretical and technical foundations behind each. This work should help the research community to structure this emerging field and identify the exact aspects which require further research and are of special significance. 2014 Elsevier Ltd. All rights reserved.
Digital image processing algorithms and applications. I[Book Review]

book goes beyond theory and techniques to address the underlying algorithms of digital image processing. It provides a complete compilation of algorithms for digital image processing , coding and analysis and includes digital image transform algorithms, edge detection algorithms, and image segmentation algorithms extracted from the literature. GPS design information, long scattered in hard-to-find places, is collected in this comprehensive reference work designed to assist engineers who use and design GPS systems. " With an emphasis on software-based signal processing—a cutting-edge approach expected to dominate future integration of GPS receivers into cellular phones…. " (The Publisher). The book covers aspects of receiver technology and relevant navigation schemes, and concentrates on civilian C/A code. The authors describe various discrete transforms and their application in different disciplines. They cover techniques such as adaptive quantization and entropy coding, which result in significant reduc-ation in bit rates when applied to the transform coefficients. Other features of the book include: L Theory of mathematical transforms in combination with techniques used in data compression L Issues fundamental to communications , image processing, and image and data storage L Classical and modern transforms, and how they relate to data compression L Compuression applications for speech analysis, pattern recognition, and medical imaging L Detailed definitions and properties of the each of the transforms presented L Lists of web sites, ftp addresses, etc. (cloth). This book is a practical guide to the state of the art of modern digital system design, combining accessible explanations and problem-solving strategies; it clarifies topics involving the effects of high frequencies on digital buses and presents techniques and application samples. The book, written by three Intel engineers, covers: L Introduction to the digital aspects of basic transmission line theory L Crosstalk and nonideal transmission line effects on signal quality and timings L The impact of packages, vias, and connectors on signal integrity L The effects of nonideal return current paths, high frequency power delivery , and simultaneous switching noise L Explanations of how driving circuit characteristis affect the quality of the digital signal L Digital timing analysis at the system level that incorporates high-speed signaling effects into timing budgets L Methodologies for designing high-speed buses and handling the very large number of variables that affect interconnect performance L Radiated emission problems and how to minimize system noise L The practical aspects of making measurements in high-speed digital systems. (The Publisher) Interconnect Analysis and Synthesis. …
Electricity Consumption and Economic Growth Nexus: A Multivariate Analysis for Turkey

This study examines the short-run and long-run causality issues between electricity consumption and economic growth in Turkey for 1968–2006 period by using Granger causality models augmented with a lagged error-correction term. The bounds F–test for cointegration test yields evidence of a long-run relationship between employment ratio, electricity consumption per capita and real GDP per capita. The overall results from the three error-correction based Granger causality models show that there is an evidence of unidirectional short-run, long-run and strong causalities running from the electricity consumption per capita to real GDP per capita. But, there is no causal evidence from the real GDP per capita to electricity consumption per capita. In other words, “Growth hypothesis” is confirmed in Turkey. This suggests that electricity consumption plays an important role in economic growth.