LLukas22/scidocs huggingface dataset:
Making AES great again: the forthcoming vectorized AES instruction

The introduction of the processor instructions AES-NI and VPCLMULQDQ, that are designed for speeding up encryption, and their continual performance improvements through processor generations, has significantly reduced the costs of encryption overheads. More and more applications and platforms encrypt all of their data and traffic. As an example, we note the world wide proliferation of the use of AES-GCM, with performance dropping down to 0.64 cycles per byte (from ∼ 23 before the instructions), on the latest Intel processors. This is close to the theoretically achievable performance with the existing hardware support. Anticipating future applications and increasing demand for high performance encryption, Intel has recently announced [1] that its future architecture (codename ”Ice Lake”) will introduce new encryption instructions. These will be able to vectorize the AES-NI and VPCLMULQDQ instructions, on wide registers that are available on the AVX512 architectures. In this paper, we explain how these new instructions can be used effectively, and how properly using them can lead to the anticipated theoretical encryption throughput of around 0.16 cycles per byte. The included examples demonstrate AES encryption in various modes of operation, AEAD such as AES-GCM, and the emerging nonce misuse resistant variant AES-GCM-SIV.
Effects of a single post-partum injection of a high dose of vitamin D on glucose tolerance and insulin resistance in mothers with first-time gestational diabetes mellitus.

AIM
This study was performed to determine the effect of a single, large, intramuscular injection of vitamin D post-partum on glucose tolerance and insulin resistance in women with gestational diabetes.


METHODS
Forty-five participants in a randomized controlled trial on gestational diabetes mellitus were divided into an intervention group and a control group. Only subjects in the intervention group received one intramuscular injection of 300,000 IU of vitamin D3. HbA(1c), serum 25-hydroxyvitamin D3, fasting insulin and blood glucose, C-peptide, homeostasis model assessment insulin resistance index (HOMA-IR), β-cell function, insulin sensitivity and the Quantitative Insulin Sensitivity Check Index (QUICKI) were measured at baseline and after 3 months of intervention.


RESULTS
Approximately 80% of the mothers had a degree of vitamin D deficiency. Post-intervention, this was found in 4.2 and 71.4% in the intervention and control groups, respectively. The medians of HOMA-IR indices before and after intervention were 0.6 and 0.5 (P = 0.7), respectively, in subjects in the intervention group, and 0.5 and 0.9 (P = 0.01) in subjects in the control group. The mean of the QUICKI fell only in the control group (P = 0.008). In the control group, β-cell function increased by ~8% (P = 0.01) and insulin sensitivity decreased after 3 months (P = 0.002). Post-intervention, the median C-peptide decreased in the intervention group and increased in the control group, but the change was significant only in the control group (P = 0.03).


CONCLUSIONS
A single injection of 300,000 IU of vitamin D3 achieves a 3-month serum 25-hydroxyvitamin D range of 50-80 nmol/l and is an efficient, effective and safe procedure for improving the vitamin status and indices of insulin resistance in mothers with gestational diabetes after delivery.
Using system simulation to model the impact of human error in a maritime system

Human error is cited as the predominant cause of transportation accidents. This paper describes the modeling of human error related accident event sequences in a risk assessment of maritime oil transportation in Prince William Sound, Alaska. The risk analysts were confronted with incomplete and misleading data that made it dicult to use theoretical frameworks. They were required, therefore, to make signi®cant modeling assumptions in order to produce valid and useful results. A two stage human error framwork was developed for the Prince William Sound Risk Assessment based on interviews with maritime experts. Conditional probabilities implied by this framework were elicited from system experts (tanker masters, mates, engineers, and state pilots) and used within a dynamic simulation to produce the risk analysis base case results discussed. The ability to quantify the eectiveness of proposed risk reduction interventions aimed at reducing human and organizational error were limited by the level of detail described by the taxonomy of human error. # 1998 Elsevier Science Ltd. All rights reserved.
Bioequivalence of two tablet formulations of capecitabine and exploration of age, gender, body surface area, and creatinine clearance as factors influencing systemic exposure in cancer patients

Purpose: The objective of the study was to assess the bioequivalence of two tablet formulations of capecitabine and to explore the effect of age, gender, body surface area and creatinine clearance on the systemic exposure to capecitabine and its metabolites. Methods: The study was designed as an open, randomized two-way crossover trial. A single oral dose of 2000 mg capecitabine was administered on two separate days to 25 patients with solid tumors. On one day, the patients received four 500-mg tablets of formulation B (test formulation) and on the other day, four 500-mg tablets of formulation A (reference formulation). The washout period between the two administrations was between 2 and 8 days. After each administration, serial blood and urine samples were collected for up to 12 and 24 h, respectively. Unchanged capecitabine and its metabolites were determined in plasma using LC/MS-MS and in urine by NMRS. Results: Based on the primary pharmacokinetic parameter, AUC0–∞ of 5′-DFUR, equivalence was concluded for the two formulations, since the 90% confidence interval of the estimate of formulation B relative to formulation A of 97% to 107% was within the acceptance region 80% to 125%. There was no clinically significant difference between the tmax for the two formulations (median 2.1 versus 2.0 h). The estimate for Cmax was 111% for formulation B compared to formulation A and the 90% confidence interval of 95% to 136% was within the reference region 70% to 143%. Overall, these results suggest no relevant difference between the two formulations regarding the extent to which 5′-DFUR reached the systemic circulation and the rate at which 5′-DFUR appeared in the systemic circulation. The overall urinary excretions were 86.0% and 86.5% of the dose, respectively, and the proportion recovered as each metabolite was similar for the two formulations. The majority of the dose was excreted as FBAL (61.5% and 60.3%), all other chemical species making a minor contribution. Univariate and multivariate regression analysis to explore the influence of age, gender, body surface area and creatinine clearance on the log-transformed pharmacokinetic parameters AUC0–∞ and Cmax of capecitabine and its metabolites revealed no clinically significant effects. The only statistically significant results were obtained for AUC0–∞ and Cmax of intact drug and for Cmax of FBAL, which were higher in females than in males. Conclusion: The bioavailability of 5′-DFUR in the systemic circulation was practically identical after administration of the two tablet formulations. Therefore, the two formulations can be regarded as bioequivalent. The variables investigated (age, gender, body surface area, and creatinine clearance) had no clinically significant effect on the pharmacokinetics of capecitabine or its metabolites.
Privacy Preserving Data Publishing: A Classification Perspective

The concept of privacy is expressed as release of information in a controlled way. Privacy could also be defined as privacy decides what type of personal information should be released and which group or person can access and use it. Privacy Preserving Data Publishing (PPDP) is a way to allow one to share anonymous data to ensure protection against identity disclosure of an individual. Data anonymization is a technique for PPDP, which makes sure the published data, is practically useful for processing (mining) while preserving individuals sensitive information. Most works reported in literature on privacy preserving data publishing for classification task handle numerical data. However, most real life data contains both numerical and non-numerical data. Another shortcoming is that use of distributed model called Secure Multiparty Computation (SMC). For this research, a centralized model is used for independent data publication by a single data owner. The key challenge for PPDP is to ensure privacy as well as to keep the data usable for research. Differential privacy is a technique that ensures the highest level of privacy for a record owner while providing actual information of the data set. The aim of this research is to develop a framework that satisfies differential privacy standards and to ensure maximum data usability for a classification tasks such as patient data classification in terms of blood pressure. Keywords—privacy preserving data publishing; differential privacy
Image quality assessment: A sparse learning way

Full reference image quality assessment is very important for many image processing applications. The challenge of image quality assessment lies in two aspects: 1) formulating perceptual meaningful features and 2) finding a way to pool them into a single quality score. A novel two-step approach is proposed to address these problems. In the first step, sparse representations of local image patches are computed to simulate the low level characteristic of the human vision system (HVS) and represent the meaningful image structures. The differences between the representations of distorted and undistorted patches are utilized to measure the local distortion. In the second step, these local distortion measurements are fused into a single image quality score by using kernel ridge regression (KRR). Kernel ridge regression can mimic the complex high level behaviors of human vision system and is shown to be an effective way to learn the relationship between local quality measurements and quality score. The contributions of this paper would be summarized as follows: 1) Extracting approximate perceptual meaningful features in image quality assessment is transformed as a sparse representation problem. In this case, the sparse representation coefficients can reflect the salient local structures and give local quality assessments. 2) The KRR is utilized to pool the local quality assessments into a single image quality score. Thus, the nonlinear relationship between the objective model outputs and the subjective quality ratings can be learned by exploiting the KRR. 3) Extensive experiments are conducted on six public databases. Compared with other approaches, the proposed approach has achieved the best performance, which demonstrates the effectiveness and robustness of the proposed approach. ∗Corresponding author. Email address: luxq666666@gmail.com (Xiaoqiang Lu) Preprint submitted to neurocomputing February 14, 2015
On the genesis of Post constraint in modern electromagnetism

Abstract The genesis of the Post constraint is premised on two attributes of modern electromagnetism: (i) its microscopic nature, and (ii) the status of
 e ˜ ( x , t ) and
 b ˜ ( x , t ) as the primitive electromagnetic fields. This constraint can therefore not arise in EH-electromagnetism, wherein the primitive electromagnetic fields are the macroscopic fields
 e ˜ ( x , t ) and
 H ˜ ( x , t ) . Available experimental evidence against the Post constraint is incomplete and inconclusive.
Polyphenol composition and in vitro antioxidant activity of amaranth , quinoa buckwheat and wheat as affected by sprouting and baking

This study examined the polyphenol composition and antioxidant properties of methanolic extracts from amaranth, quinoa, buckwheat and wheat, and evaluated how these properties were affected following two types of processing: sprouting and baking. The total phenol content amongst the seed extracts were significantly higher in buckwheat (323.4 mgGAE/100 g) and decreased in the following order: buckwheat > quinoa > wheat > amaranth. Antioxidant capacity, measured by the radical 2,2-diphenyl-1-picylhydrazyl scavenging capacity and the ferric ion reducing antioxidant power assays was also highest for buckwheat seed extract (p < 0.01). Total phenol content and antioxidant activity was generally found to increase with sprouting, and a decrease in levels was observed following breadmaking. Analysis by liquid chromatography coupled with diode array detector revealed the presence of phenolic acids, catechins, flavanol, flavone and flavonol glycosides. Overall, quinoa and buckwheat seeds and sprouts represent potential rich sources of polyphenol compounds for enhancing the nutritive properties of foods such as gluten-free breads. 2009 Elsevier Ltd. All rights reserved.
Postprandial Symptoms Felt at the Lower Part of the Epigastrium and a Possible Association of Pancreatic Exocrine Dysfunction with the Pathogenesis of Functional Dyspepsia

Objective In symptom-dependent diseases such as functional dyspepsia (FD), matching the pattern of epigastric symptoms, including severity, kind, and perception site, between patients and physicians is critical. Additionally, a comprehensive examination of the stomach, duodenum, and pancreas is important for evaluating the origin of such symptoms. Methods FD-specific symptoms (epigastric pain, epigastric burning, early satiety, and postprandial fullness) and other symptoms (regurgitation, nausea, belching, and abdominal bloating) as well as the perception site of the above symptoms were investigated in healthy subjects using a new questionnaire with an illustration of the human body. A total of 114 patients with treatment-resistant dyspeptic symptoms were evaluated for their pancreatic exocrine function using N-benzoyl-L-tyrosyl-p-aminobenzoic acid. Results A total of 323 subjects (men:women, 216:107; mean age, 52.1 years old) were initially enrolled. Most of the subjects felt the FD-specific symptoms at the epigastrium, while about 20% felt them at other abdominal sites. About 30% of expressed as epigastric symptoms were FD-nonspecific symptoms. At the epigastrium, epigastric pain and epigastric burning were mainly felt at the upper part, and postprandial fullness and early satiety were felt at the lower part. The prevalence of patients with pancreatic exocrine dysfunction was 71% in the postprandial fullness group, 68% in the epigastric pain group, and 82% in the diarrhea group. Conclusion We observed mismatch in the perception site and expression between the epigastric symptoms of healthy subjects and FD-specific symptoms. Postprandial symptoms were often felt at the lower part of the epigastrium, and pancreatic exocrine dysfunction may be involved in the FD symptoms, especially for treatment-resistant dyspepsia patients.
An evaluation of TCP splice benefits in web proxy servers

This study is the first to evaluate the performance benefits of using the recently proposed TCP Splice kernel service in Web proxy servers. Previous studies show that splicing client and server TCP connections in the IP layer improves the throughput of proxy servers like firewalls and content routers by reducing the data transfer overheads. In a Web proxy server, data transfer overheads represent a relatively large fraction of the request processing overheads, in particular when content is not cacheable or the proxy cache is memory-based. The study is conducted with a socket-level implementation of TCP Splice. Compared to IP-level implementations, socket-level implementations make possible the splicing of connections with different TCP characteristics, and improve response times by reducing recovery delay after a packet loss. The experimental evaluation is focused on HTTP request types for which the proxy can fully exploit the TCP Splice service, which are the requests for non-cacheabl.content and SSL tunneling. The experimental testbed includes an emulated WAN environment and benchmark applications for HTTP/1.0 Web client, Web server, and Web proxy running on AIX RS/6000 machines. Our experiments demonstrate that TCP Splice enables reductions in CPU utilization of 10-43% of the CPU, depending on file sizes and request rates. Larger relative reductions are observed when tunneling SSL connections, in particular for small file transfers. Response times are also reduced by up to 1.8sec.
The Potential of Neuromarketing as a Marketing Tool

In recent years, the emerging field of neuromarketing, which makes use of brain research in a managerial context, has gained increasing popularity in the academic literature as well as the practical world. Therefore, the purpose of the present paper is to evaluate upon the influence of neuromarketing tools on traditional marketing inputs in order to complete the understanding of consumer behavior. Yet, no available neuromarketing study provided an detailed overview of neuromarketing‘s influence on traditional marketing inputs while considering technical as well as ethical issues. The article uses the approach of an in-depth literature review in order to do so. The increased use of neuromarketing techniques for the evaluation of customer preferences and decision-making processes is considered to be an advantage for customers and marketers simultaneously. EEG, fMRI and MEG rank among the most appropriate technicalities in the area of neuroscience. However, critics emphasize the restriction of the consumer‘s free will and their reduced ability to make individual decisions in their buying behavior due to neuromarketing‘s implementation. After an evaluation of Outside reflexes, input-/Output models and Inside reflexes to analyze brain activities, the current paper evaluates upon the influence of neuromarketing on different relevant marketing inputs, followed by the consideration of its ethical defensibleness. The results indicate that neuromarketing is associated to have a high influence on consumer buying behavior, advertising, pricing, distribution of products, branding and decision-making as marketing inputs. Therefore, neuromarketing may be considered to be a remarkable extension in the research of human behavior and the brain as the ―black box‖ which can positively contribute to its practical applicableness. Supervisors: Efthymios Constantinides
Right-handed double-helix ultrashort DNA yields chiral nematic phases with both right- and left-handed director twist.

Concentrated solutions of duplex-forming DNA oligomers organize into various mesophases among which is the nematic (N(∗)), which exhibits a macroscopic chiral helical precession of molecular orientation because of the chirality of the DNA molecule. Using a quantitative analysis of the transmission spectra in polarized optical microscopy, we have determined the handedness and pitch of this chiral nematic helix for a large number of sequences ranging from 8 to 20 bases. The B-DNA molecule exhibits a right-handed molecular double-helix structure that, for long molecules, always yields N(∗) phases with left-handed pitch in the μm range. We report here that ultrashort oligomeric duplexes show an extremely diverse behavior, with both left- and right-handed N(∗) helices and pitches ranging from macroscopic down to 0.3 μm. The behavior depends on the length and the sequence of the oligomers, and on the nature of the end-to-end interactions between helices. In particular, the N(∗) handedness strongly correlates with the oligomer length and concentration. Right-handed phases are found only for oligomers shorter than 14 base pairs, and for the sequences having the transition to the N(∗) phase at concentration larger than 620 mg/mL. Our findings indicate that in short DNA, the intermolecular double-helical interactions switch the preferred liquid crystal handedness when the columns of stacked duplexes are forced at high concentrations to separations comparable to the DNA double-helix pitch, a regime still to be theoretically described.
Joint Tx-Rx beamforming design for multicarrier MIMO channels: a unified framework for convex optimization

This paper addresses the joint design of transmit and receive beamforming or linear processing (commonly termed linear precoding at the transmitter and equalization at the receiver) for multicarrier multi-input multi-output (MIMO) channels under a variety of design criteria. Instead of considering each design criterion in a separate way, we generalize the existing results by developing a unified framework based on considering two families of objective functions that embrace most reasonable criteria to design a communication system: Schur-concave and Schur-convex functions. Once the optimal structure of the transmit-receive processing is known, the design problem simplifies and can be formulated within the powerful framework of convex optimization theory, in which a great number of interesting design criteria can be easily accommodated and efficiently solved even though closed-form expressions may not exist. From this perspective, we analyze a variety of design criteria and, in particular, we derive optimal beamvectors in the sense of having minimum average bit error rate (BER). Additional constraints on the Peak-to-Average Ratio (PAR) or on the signal dynamic range are easily included in the design. We propose two multi-level water-filling practical solutions that perform very close to the optimal in terms of average BER with a low implementation complexity. If cooperation among the processing operating at different carriers is allowed, the performance improves significantly. Interestingly, with carrier cooperation, it turns out that the exact optimal solution in terms of average BER can be obtained in closed-form. Manuscript received February 25, 2002; revised December 20, 2002. Part of the work was presented at the 40th Annual Allerton Conference on Communication, Control, and Computing, Monticello, IL, Oct. 2002 [37] . This work was partially supported by the European Comission under Project IST-2000-30148 I-METRA; Samsung Advanced Institute of Technology; the Spanish Government (CICYT) TIC2000-1025, TIC2001-2356, TIC2002-04594, FIT-070000-2000-649 (MEDEA + A105 UniLAN); and the Catalan Government (DURSI) 1999FI 00588, 2001SGR 00268.
Rollback and Forking Detection for Trusted Execution Environments Using Lightweight Collective Memory

Novel hardware-aided trusted execution environments, as provided by Intel's Software Guard Extensions (SGX), enable to execute applications in a secure context that enforces confidentiality and integrity of the application state even when the host system is misbehaving. While this paves the way towards secure and trustworthy cloud computing, essential system support to protect persistent application state against rollback and forking attacks is missing. In this paper we present LCM – a lightweight protocol to establish a collective memory amongst all clients of a remote application to detect integrity and consistency violations. LCM enables the detection of rollback attacks against the remote application, enforces the consistency notion of fork-linearizability and notifies clients about operation stability. The protocol exploits the trusted execution environment, complements it with simple client-side operations, and maintains only small, constant storage at the clients. This simplifies the solution compared to previous approaches, where the clients had to verify all operations initiated by other clients. We have implemented LCM and demonstrated its advantages with a key-value store application. The evaluation shows that it introduces low network and computation overhead, in particular, a LCM-protected key-value store achieves 0.72x – 0.98x of an SGX-secured key-value store throughput.