LLukas22/scidocs huggingface dataset:
Detection of depression in low resource settings: validation of the Patient Health Questionnaire (PHQ-9) and cultural concepts of distress in Nepal.

BACKGROUND
Despite recognition of the burden of disease due to mood disorders in low- and middle-income countries, there is a lack of consensus on best practices for detecting depression. Self-report screening tools, such as the Patient Health Questionnaire (PHQ-9), require modification for low literacy populations and to assure cultural and clinical validity. An alternative approach is to employ idioms of distress that are locally salient, but these are not synonymous with psychiatric categories. Therefore, our objectives were to evaluate the validity of the PHQ-9, assess the added value of using idioms of distress, and develop an algorithm for depression detection in primary care.


METHODS
We conducted a transcultural translation of the PHQ-9 in Nepal using qualitative methods to achieve semantic, content, technical, and criterion equivalence. Researchers administered the Nepali PHQ-9 to randomly selected patients in a rural primary health care center. Trained psychosocial counselors administered a validated Nepali depression module of the Composite International Diagnostic Interview (CIDI) to validate the Nepali PHQ-9. Patients were also assessed for local idioms of distress including heart-mind problems (Nepali, manko samasya).


RESULTS
Among 125 primary care patients, 17 (14 %) were positive for a major depressive episode in the prior 2 weeks based on CIDI administration. With a Nepali PHQ-9 cutoff ≥ 10: sensitivity = 0.94, specificity = 0.80, positive predictive value (PPV) =0.42, negative predictive value (NPV) =0.99, positive likelihood ratio = 4.62, and negative likelihood ratio = 0.07. For heart-mind problems: sensitivity = 0.94, specificity = 0.27, PPV = 0.17, NPV = 0.97. With an algorithm comprising two screening questions (1. presence of heart-mind problems and 2. function impairment due to heart-mind problems) to determine who should receive the full PHQ-9, the number of patients requiring administration of the PHQ-9 could be reduced by 50 %, PHQ-9 false positives would be reduced by 18 %, and 88 % of patients with depression would be correctly identified.


CONCLUSION
Combining idioms of distress with a transculturally-translated depression screener increases efficiency and maintains accuracy for high levels of detection. The algorithm reduces the time needed for primary healthcare staff to verbally administer the tool for patients with limited literacy. The burden of false positives is comparable to rates in high-income countries and is a limitation for universal primary care screening.
An Interval Classifier for Database Mining Applications

We are given a large population database that contains information about population instances. The population is known to comprise of m groups, but the population instances are not labeled with the group identi cation. Also given is a population sample (much smaller than the population but representative of it) in which the group labels of the instances are known. We present an interval classi er (IC) which generates a classi cation function for each group that can be used to e ciently retrieve all instances of the specied group from the population database. To allow IC to be embedded in interactive loops to answer adhoc queries about attributes with missing values, IC has been designed to be e cient in the generation of classi cation functions. Preliminary experimental results indicate that IC not only has retrieval and classi er generation e ciency advantages, but also compares favorably in the classi cation accuracy with current tree classi ers, such as ID3, which were primarily designed for minimizing classi cation errors. We also describe some new applications that arise from encapsulating the classi cation capability in database systems and discuss extensions to IC for it to be used in these new application domains. Current address: Computer Science Department, Rutgers University, NJ 08903 Permission to copy without fee all or part of this material is granted provided that the copies are not made or distributed for direct commercial advantage, the VLDB copyright notice and the title of the publication and its date appear, and notice is given that copying is by permission of the Very Large Data Base Endowment. To copy otherwise, or to republish, requires a fee and/or special permission from the Endowment. Proceedings of the 18th VLDB Conference Vancouver, British Columbia, Canada 1992
A tutorial on support vector regression

In this tutorial we give an overview of the basic ideas underlying Support Vector (SV) machines for function estimation. Furthermore, we include a summary of currently used algorithms for training SV machines, covering both the quadratic (or convex) programming part and advanced methods for dealing with large datasets. Finally, we mention somemodifications and extensions that have been applied to the standard SV algorithm, and discuss the aspect of regularization from a SV perspective.
Efficacy of maternal tenofovir disoproxil fumarate in interrupting mother-to-infant transmission of hepatitis B virus.

UNLABELLED
The efficacy and safety of maternal tenofovir disoproxil fumarate (TDF) in reducing mother-to-infant hepatitis B virus (HBV) transmissions is not clearly understood. We conducted a prospective, multicenter trial and enrolled 118 hepatitis B surface antigen (HBsAg)- and hepatitis B e antigen-positive pregnant women with HBV DNA ≥7.5 log10 IU/mL. The mothers received no medication (control group, n = 56, HBV DNA 8.22 ± 0.39 log10 IU/mL) or TDF 300 mg daily (TDF group, n = 62, HBV DNA 8.18 ± 0.47 log10 IU/mL) from 30-32 weeks of gestation until 1 month postpartum. Primary outcome was infant HBsAg at 6 months old. At delivery, the TDF group had lower maternal HBV DNA levels (4.29 ± 0.93 versus 8.10 ± 0.56 log10 IU/mL, P < 0.0001). Of the 121/123 newborns, the TDF group had lower rates of HBV DNA positivity at birth (6.15% versus 31.48%, P = 0.0003) and HBsAg positivity at 6 months old (1.54% versus 10.71%, P = 0.0481). Multivariate analysis revealed that the TDF group had lower risk (odds ratio = 0.10, P = 0.0434) and amniocentesis was associated with higher risk (odds ratio 6.82, P = 0.0220) of infant HBsAg positivity. The TDF group had less incidence of maternal alanine aminotransferase (ALT) levels above two times the upper limit of normal for ≥3 months (3.23% versus 14.29%, P = 0.0455), a lesser extent of postpartum elevations of ALT (P = 0.007), and a lower rate of ALT over five times the upper limit of normal (1.64% versus 14.29%, P = 0.0135) at 2 months postpartum. Maternal creatinine and creatinine kinase levels, rates of congenital anomaly, premature birth, and growth parameters in infants were comparable in both groups. At 12 months, one TDF-group child newly developed HBsAg positivity, presumably due to postnatal infection and inefficient humoral responses to vaccines.


CONCLUSIONS
Treatment with TDF for highly viremic mothers decreased infant HBV DNA at birth and infant HBsAg positivity at 6 months and ameliorated maternal ALT elevations. (Hepatology 2015;62:375-386.
Applying Clustering of Hierarchical K-means-like Algorithm on Arabic Language

In this study a clustering technique has been implemented which is K-Means like with hierarchical initial set (HKM). The goal of this study is to prove that clustering document sets do enhancement precision on information retrieval systems, since it was proved by Bellot & El-Beze on French language. A comparison is made between the traditional information retrieval system and the clustered one. Also the effect of increasing number of clusters on precision is studied. The indexing technique is Term Frequency * Inverse Document Frequency (TF * IDF). It has been found that the effect of Hierarchical K-Means Like clustering (HKM) with 3 clusters over 242 Arabic abstract documents from the Saudi Arabian National Computer Conference has significant results compared with traditional information retrieval system without clustering. Additionally it has been found that it is not necessary to increase the number of clusters to improve precision more. Keywords—Hierarchical K-mean like clustering (HKM), Kmeans, cluster centroids, initial partition, and document distances
Low power radiofrequency electromagnetic radiation for the treatment of pain due to osteoarthritis of the knee.

OBJECTIVE
To investigate the analgesic effect of low power radiofrequency electromagnetic radiation (RF) in osteoarthritis (OA) of the knee.


METHODS
In a randomized study on 40 patients the analgesic effect of RF was compared with the effect of transcutaneous electrical nerve stimulation (TENS). RF and TENS applications were repeated every day for a period of 5 days. The therapeutic effect was evaluated by a visual analogue scale (VAS) and by Lequesne's index: tests were performed before, immediately after and 30 days after therapy.


RESULTS
RF therapy induced a statistically significant and long lasting decrease of VAS and of Lequesne's index; TENS induced a decrease of VAS and of Lequesne's index which was not statistically significant.


CONCLUSIONS
A therapeutic effect of RF was therefore demonstrated on pain and disability due to knee OA. This effect was better than the effect of TENS, which is a largely used analgesic technique. Such a difference of the therapeutic effect may be due to the fact that TENS acts only on superficial tissues and nerve terminals, while RF acts increasing superficial and deep tissue temperature.
Alcohol-facilitated ankylosis of the distal intertarsal and tarsometatarsal joints in horses with osteoarthritis.

OBJECTIVE
To assess the safety and efficacy of alcohol-facilitated ankylosis of the distal intertarsal (DIT) and tarsometatarsal (TMT) joints in horses with osteoarthritis (bone spavin).


DESIGN
Prospective clinical trial.


ANIMALS
21 horses with DIT or TMT joint-associated hind limb lameness and 5 nonlame horses.


PROCEDURES
11 horses (group 1) underwent lameness, force-plate, and radiographic examinations; following intra-articular analgesia, lameness and force-plate examinations were repeated. Nonlame horses were used for force-plate data acquisition only. Following localization of lameness to the DIT and TMT joints, contrast arthrographic evaluation was performed; when communication with the tibiotarsal joint was not evident or suspected, 70% ethyl alcohol (3 mL) was injected. Group 1 horses underwent lameness, force-plate, and radiographic examinations every 3 months for 1 year. Ten other horses (group 2) underwent lameness and radiographic examinations followed by joint injection with alcohol; follow-up information was obtained from owners or via clinical examination.


RESULTS
Significant postinjection reduction in lameness (after 3 days to 3 months) was evident for all treated horses. Twelve months after injection, 10 of 11 group 1 horses were not lame; lameness grade was 0.5 in 1 horse. Follow-up information was available for 9 of 10 group 2 horses; 7 were not lame, and 2 remained mildly lame (1 had a concurrent problem in the injected limb, and the other had DIT joint collapse that precluded needle entry).


CONCLUSIONS AND CLINICAL RELEVANCE
Intra-articular alcohol injection in horses with bone spavin resulted in a rapid (usually within 3 months) reduction in lameness and joint space collapse.
Standoff Detection of Weapons and Contraband in the 100 GHz to 1 THz Region

The techniques and technologies currently being investigated to detect weapons and contraband concealed on persons under clothing are reviewed. The basic phenomenology of the atmosphere and materials that must be understood in order to realize such a system are discussed. The component issues and architectural designs needed to realize systems are outlined. Some conclusions with respect to further technology developments are presented.
Environmental Science & Policy

ENVIRONMENTAL SCIENCE & POLICY. BA Academic year 2016-2017 College: Arts and Sciences Degree: B.A. Limited Access: NO Contact: Mr. Tim McGann (advising) Dr. Jeff Chanton (program information) Address: Dept. of Earth, Ocean and Atmospheric Science Tallahassee, FL 32306-4320 McGann 111 CAR Chanton: 305 OSB Phone: McGann: (850) 644-8582 Chanton: (850) 644-7493 E-Mail: tmcgann@fsu.edu jchanton@fsu.edu
Fleets of robots for precision agriculture: a simulation environment

Purpose – The purpose of this paper is to propose going one step further in the simulation tools related to agriculture by integrating fleets of mobile robots for the execution of precision agriculture techniques. The proposed new simulation environment allows the user to define different mobiles robots and agricultural implements. Design/methodology/approach – With this computational tool, the crop field, the fleet of robots and the different sensors and actuators that are incorporated into each robot can be configured by means of two interfaces: a configuration interface and a graphical interface, which interact with each other. Findings – The system presented in this article unifies two very different areas – robotics and agriculture – to study and evaluate the implementation of precision agriculture techniques in a 3D virtual world. The simulation environment allows the users to represent realistic characteristics from a defined location and to model different variabilities that may affect the task performance accuracy of the fleet of robots. Originality/value – This simulation environment, the first in incorporating fleets of heterogeneous mobile robots, provides realistic 3D simulations and videos, which grant a good representation and a better understanding of the robot labor in agricultural activities for researchers and engineers from different areas, who could be involved in the design and application of precision agriculture techniques. The environment is available at the internet, which is an added value for its expansion in the agriculture/robotics family.
Square Monopole Antenna for UWB Applications With Novel Rod-Shaped Parasitic Structures and Novel V-Shaped Slots in the Ground Plane

A novel band-notched ultrawideband monopole antenna is presented. The proposed antenna consists of a stepped square radiating patch, two rod-shaped parasitic structures for generating band-notched function instead of changing the patch or feeding shapes, and a notched ground plane with two novel V-shaped slots that provide a wide usable bandwidth of more than 200% (3-22.5 GHz). With two rod-shaped parasitic structures, frequency band-stop performance is generated, and characteristics such as band-notch frequency and bandwidth can be controlled. The designed antenna has a small size of 12 × 18 mm2 while showing the band-rejection performance in the frequency band of 5.1/5.9 GHz. The bandwidth of proposed antenna is wider than the bandwidth of antenna in the references.
Laban Movement Analysis Using a Bayesian Model and Perspective Projections

Human movement is essentially the process of moving one or more body parts to a specific location along a certain trajectory. A person observing the movement might be able to recognize it through the spatial pathway alone. Kendon (Kendon, 2004) holds the view that willingly or not, humans, when in co-presence, continuously inform one another about their intentions, interests, feelings and ideas by means of visible bodily action. Analysis of face-toface interaction has shown that bodily action can play a crucial role in the process of interaction and communication. Kendon states that expressive actions like greeting, threat and submission often play a central role in social interaction. In order to access the expressive content of movements theoretically, a notational system is needed. Rudolf Laban, (1879-1958) was a notable central European dance artist and theorist, whose work laid the foundations for Laban Movement Analysis (LMA). Used as a tool by dancers, athletes, physical and occupational therapists, it is one of the most widely used systems of human movement analysis. Robotics has already acknowledged the evidence that human movements could be an important cue for Human-Robot Interaction. Sato et al. (Sato et al., 1996), while defining the requirements for 'human symbiosis robotics' state that those robots should be able to use non-verbal media to communicate with humans and exchange information. As input modalities on a higher abstraction level they define channels on language, gesture and unconscious behavior. This skill could enable the robot to actively perceive human behavior, whether conscious and unconscious. Human intention could be understood, simply by observation, allowing the system to achieve a certain level of friendliness, hospitality and reliance. Fong, Nourbakhsh and Dautenhahn (Fong et al., 2003) state in their survey on 'socially interactive robots' that the design of sociable robots needs input from research concerning social learning and imitation, gesture and natural language communication, emotion and recognition of interaction patterns. Otero et al. suggest (Otero et al., 2006) that the interpretation of a person’s motion within its environment can enhance Human-Robot Interaction in several ways. They point out, that a recognized action can help the robot to plan its future tasks and goals, that the information flow during interaction can be extended and additional cues, like speech recognition, can be supported. Otero et al. state that body motion and context provide in many situations enough information to derive the person’s current activity.
Infants’ developing understanding of the link between looker and object

Three studies investigated infants’ understanding that gaze involves a relation between a person and the object of his or her gaze. Infants were habituated to an event in which an actor turned and looked at one of two toys. Then, infants saw test events in which (1) the actor turned to the same side as during habituation to look at a different toy, or (2) the actor turned to the other side to look at the same toy as during habituation. The first of these involved a change in the relation between actor and object. The second involved a new physical motion on the part of the actor but no change in the relation between actor and object. Sevenand 9-month-old infants did not respond to the change in relation between actor and object, although infants at both ages followed the actor’s gaze to the toys. In contrast, 12-month-old infants responded to the change in the actor–object relation. Control conditions verified that the paradigm was a sensitive index of the younger infants’ representations of action: 7and 9-month-olds responded to a change in the actor–object relation when the actor’s gaze was accompanied by a grasp. Taken together, these findings indicate that gaze-following does not initially go hand in hand with understanding the relation between a person who looks and the object of his or her gaze, and that infants begin to understand this relation between 9 and
A phase Ib dose-escalation study of everolimus combined with cisplatin and etoposide as first-line therapy in patients with extensive-stage small-cell lung cancer.

BACKGROUND
This phase Ib study aimed to establish the feasible everolimus dose given with standard-dose etoposide plus cisplatin (EP) for extensive-stage small-cell lung cancer (SCLC).


PATIENTS AND METHODS
An adaptive Bayesian dose-escalation model and investigator opinion were used to identify feasible daily or weekly everolimus doses given with EP in adults with treatment-naive extensive-stage SCLC. A protocol amendment mandated prophylactic granulocyte colony-stimulating factor (G-CSF). Primary end point was cycle 1 dose-limiting toxicity (DLT) rate. Secondary end points included safety, relative EP dose intensity, pharmacokinetics, and tumor response.


RESULTS
Patients received everolimus 2.5 or 5 mg/day without G-CSF (n=10; cohort A), 20 or 30 mg/week without G-CSF (n=18; cohort B), or 2.5 or 5 mg/day with G-CSF (n=12; cohort C); all received EP. Cycle 1 DLT rates were 50.0%, 22.2%, and 16.7% in cohorts A, B, and C, respectively. Cycle 1 DLTs were neutropenia (cohorts A and B), febrile neutropenia (all cohorts), and thrombocytopenia (cohorts A and C). The most common grade 3/4 adverse events were hematologic. Best overall response was partial response (40.0%, 61.1%, and 58.3% in cohorts A, B, and C, respectively).


CONCLUSIONS
Everolimus 2.5 mg/day plus G-CSF was the only feasible dose given with standard-dose EP in untreated extensive-stage SCLC.
Cardiac surgery is successful in heart transplant recipients.

BACKGROUND
Improved survival of heart transplant (HTx) recipients and increased acceptance of higher risk donors allows development of late pathology. However, there are few data to guide surgical options. We evaluated short-term outcomes and mortality to guide pre-operative assessment, planning, and post-operative care.


METHODS
Single centre, retrospective review of 912 patients who underwent HTx from February 1984 - June 2012, identified 22 patients who underwent subsequent cardiac surgery. Data are presented as median (IQR).


RESULTS
Indications for surgery were coronary allograft vasculopathy (CAV) (n=10), valvular disease (n=6), infection (n=3), ascending aortic aneurysm (n=1), and constrictive pericarditis (n=2). There was one intraoperative death (myocardial infarction). Hospital stay was 10 (8-21) days. Four patients (18%) returned to theatre for complications. After cardiac surgery, survival at one, five and 10 years was 91±6%, 79±10% and 59±15% with a follow-up of 4.6 (1.7-10.2) years. High pre-operative creatinine was a univariate risk factor for mortality, HR=1.028, (95%CI 1.00-1.056; p=0.05). A time dependent Cox proportional hazards model of the risk of cardiac surgery post-HTx showed no significant hazard; HR=0.87 (95%CI 0.37-2.00; p=0.74).


CONCLUSIONS
Our experience shows cardiac surgery post-HTx is associated with low mortality, and confirms that cardiac surgery is appropriate for selected HTx recipients.
On the Expansion of Environmental Protection Themes in Journal of Environment and Behavior

Metrology is employed for the statistics in studying the changes of the environmental protection themes in Journal of Environment and Behavior in U.S.since its publication.It is found that there are two main changes:from the initial concerns about the environmental awareness,attitudes and environmental education to the recent concerns about environmental behavior;and from focusing on local environmental problems to global ecological problems.
Knowledge management, codification and tacit knowledge

Introduction. This article returns to a theme addressed in Vol. 8(1) October 2002 of the journal: knowledge management and the problem of managing tacit knowledge. Method. The article is primarily a review and analysis of the literature associated with the management of knowledge. In particular, it focuses on the works of a group of economists who have studied the transformation of knowledge into information through the process of codification and the knowledge transaction topography they have developed to describe this process. Analysis. The article explores the theoretical and philosophical antecedents of the economists' views. It uses this as a basis for examining the dominant views of knowledge that appear in much of the literature on knowledge management and for performing a critical evaluation of their work. Results. The results of the analysis centre upon the question of when is it appropriate to codify knowledge. They present a basic summary of the costs and benefits of codification before looking in more detail at its desirability. Conclusions. The conclusions concern the implications of the above for knowledge management and the management of tacit knowledge. They deal with the nature of knowledge management, some of the reasons why knowledge management projects fail to achieve their expectations and the potential problems of codification as a strategy for knowledge management.