LLukas22/scidocs huggingface dataset:
Does the literature support double-row suture anchor fixation for arthroscopic rotator cuff repair? A systematic review comparing double-row and single-row suture anchor configuration.

PURPOSE
The purpose of this study was to compare the clinical outcome of single-row (SR) and double-row (DR) suture anchor fixation in arthroscopic rotator cuff repair with a systematic review of the published literature.


METHODS
We searched all published literature from January 1966 to December 2008 using Medline, CINAHL (Cumulative Index to Nursing and Allied Health Literature), and the Cochrane Central Register of Controlled Trials for the following key words: shoulder, rotator cuff, rotator cuff tear, rotator cuff repair, arthroscopic, arthroscopic-assisted, single row, double row, and transosseous equivalent. The inclusion criteria were cohort studies (Levels I to III) that compared SR and DR suture anchor configuration for the arthroscopic treatment of full-thickness rotator cuff tears. The exclusion criteria were studies that lacked a comparison group, and, therefore, case series were excluded from the analysis.


RESULTS
There were 5 studies that met the criteria and were included in the final analysis: 5 in the SR group and 5 in the DR group. Data were abstracted from the studies for patient demographics, rotator cuff tear characteristics, surgical procedure, rehabilitation, range of motion, clinical scoring systems, and imaging studies.


CONCLUSIONS
There are no clinical differences between the SR and DR suture anchor repair techniques for arthroscopic rotator cuff repairs. At present, the data in the published literature do not support the use of DR suture anchor fixation to improve clinical outcome, but there are some studies that report that DR suture anchor fixation may improve tendon healing.


LEVEL OF EVIDENCE
Level III, systematic review of Levels I to III studies.
All models are wrong: reflections on becoming a systems scientist†

Thoughtful leaders increasingly recognize that we are not only failing to solve the persistent problems we face, but are in fact causing them. System dynamics is designed to help avoid such policy resistance and identify high-leverage policies for sustained improvement. What does it take to be an effective systems thinker, and to teach system dynamics fruitfully? Understanding complex systems requires mastery of concepts such as feedback, stocks and flows, time delays, and nonlinearity. Research shows that these concepts are highly counterintuitive and poorly understood. It also shows how they can be taught and learned. Doing so requires the use of formal models and simulations to test our mental models and develop our intuition about complex systems. Yet, though essential, these concepts and tools are not sufficient. Becoming an effective systems thinker also requires the rigorous and disciplined use of scientific inquiry skills so that we can uncover our hidden assumptions and biases. It requires respect and empathy for others and other viewpoints. Most important, and most difficult to learn, systems thinking requires understanding that all models are wrong and humility about the limitations of our knowledge. Such humility is essential in creating an environment in which we can learn about the complex systems in which we are embedded and work effectively to create the world we truly desire. The paper is based on the talk the author delivered at the 2002 International System Dynamics Conference upon presentation of the Jay W. Forrester Award. Copyright  2002 John Wiley & Sons, Ltd.
Online Topic-aware Influence Maximization Queries

Influence maximization is the key algorithmic problem behind viral marketing: it requires to identify a set of influential users in a social network, who, when convinced to adopt a product, shall influence other users in the network, leading to a large number of adoptions. Although real world users evidently have di↵erent degrees of interest and authoritativeness on di↵erent topics, the bulk of the literature on influence maximization is topic-blind, in the sense that it treats all items as they were the same. In this paper we study Topic-aware Influence Maximization (TIM) queries: given a directed social graph, where the arcs are associated with a topic-dependent user-to-user social influence strength, and given a budget k, the problem requires to find a set of k users (named seed set) that we shall target in a viral marketing campaign for a given new item (described as a distribution over topics) in order to maximize its adoption. Our goal is to answer such queries in milliseconds, thus enabling online social influence analytics, what-if simulation, and marketing decision making. The main challenge here is the enormous number of potential queries: any possible distribution over the topic space (i.e., any possible item) induces a di↵erent probabilistic graph, and thus a di↵erent instance of the standard influence maximization problem, for which e ciency and scalability are still unsolved problems. Given these computational challenges, we propose to build an index over pre-computed solutions for a limited number of possible queries. Our proposal, INFLEX, employs a treebased index for similarity search with Bregman divergences, to e ciently retrieve a good-enough set of neighbor points for the query item. Then it performs rank aggregation on their seed sets to produce the final answer to the query. Experimental results on real data show that INFLEX can provide in few milliseconds a solution very similar (Kendall⌧ distance < 0.1) to the one produced by the best known o✏ine computation (which usually takes several days). (c) 2014, Copyright is with the authors. Published in Proc. 17th International Conference on Extending Database Technology (EDBT), March 24-28, 2014, Athens, Greece: ISBN 978-3-89318065-3, on OpenProceedings.org. Distribution of this paper is permitted under the terms of the Creative Commons license CC-by-nc-nd 4.0
Histological Correlates of Penile Sexual Sensation: Does Circumcision Make a Difference?

INTRODUCTION
The question of whether removal of sensory receptors in the prepuce by circumcision affects sensitivity and/or sexual pleasure is often debated.


AIMS
To examine histological correlates relevant to penile sensitivity and sexual pleasure.


METHODS
Systematic review of the scientific literature on penile structures that might affect sensitivity and sexual sensation. Articles were included if they contained original data on human male penile histology or anatomy. Individual articles, including reference lists, were evaluated. They were then considered in relation to physiological data from articles retrieved by a previous systematic review.


RESULTS
We retrieved 41 publications on penile structure. Considered in the light of 12 reporting physiological measurements, our evaluation finds that sexual response is unlikely to involve Meissner's corpuscles, whose density in the prepuce diminishes at the time of life when male sexual activity is increasing. Free nerve endings also show no correlation with sexual response. Because tactile sensitivity of the glans decreases with sexual arousal, it is unrelated to sexual sensation. Thermal sensitivity seems part of the reward mechanism of intercourse. Vibrational sensitivity is not related to circumcision status. Observations that penile sexual sensation is higher post circumcision are consistent with greater access of genital corpuscles to sexual stimuli after removal of the prepuce. This is based on the distribution of these corpuscles (which are located in the glans) and, in uncircumcised men, the position of the retracted prepuce during intercourse, rather than any change in the number of genital corpuscles. The scientific literature suggests that any sexual effect of circumcised men may depend solely on exposure of the glans and not on the absence of the prepuce.


CONCLUSION
Based on histological findings and correlates of sexual function, loss of the prepuce by circumcision would appear to have no adverse effect on sexual pleasure. Our evaluation supports overall findings from physiological measurements and survey data.
In between self-knowledge and school demands. : Policy enacted in the Swedish middle year classroom.

In a recent series of articles Braun et al highlights the importance of studying the ways that policy is enacted by teachers in their everyday work attending the material and discursive contingenci ...
Design of a flexible tactile sensor for classification of rigid and deformable objects

For both humans and robots, tactile sensing is important for interaction with the environment: it is the core sensing used for exploration and manipulation of objects. In this paper, we present a novel tactile-array sensor based on flexible piezoresistive rubber. We describe the design of the sensor and data acquisition system.We evaluate the sensitivity and robustness of the sensor, and show that it is consistent over time with little relaxation. Furthermore, the sensor has the benefit of being flexible, having a high resolution, it is easy to mount, and simple to manufacture. We demonstrate the use of the sensor in an active object-classification system. A robotic gripper with two sensors mounted on its fingers performs a palpation procedure on a set of objects. By squeezing an object, the robot actively explores the material properties, and the system acquires tactile information corresponding to the resulting pressure. Based on a k nearest neighbor classifier and using dynamic time warping to calculate the distance between different time series, the system is able to successfully classify objects. Our sensor demonstrates similar classification performance to the Weiss Robotics tactile sensor, while having additional benefits. © 2012 Elsevier B.V. All rights reserved.
Modeling and design of global logistics systems: A review of integrated strategic and tactical models and design algorithms

The overall focus of this research is to demonstrate the savings potential generated by the integration of the design of strategic global supply chain networks with the determination of tactical production–distribution allocations and transfer prices. The logistics systems design problem is defined as follows: given a set of potential suppliers, potential manufacturing facilities, and distribution centers with multiple possible configurations, and customers with deterministic demands, determine the configuration of the production–distribution system and the transfer prices between various subsidiaries of the corporation such that seasonal customer demands and service requirements are met and the after tax profit of the corporation is maximized. The after tax profit is the difference between the sales revenue minus the total system cost and taxes. The total cost is defined as the sum of supply, production, transportation, inventory, and facility costs. Two models and their associated solution algorithms will be introduced. The savings opportunities created by designing the system with a methodology that integrates strategic and tactical decisions rather than in a hierarchical fashion are demonstrated with two case studies. The first model focuses on the setting of transfer prices in a global supply chain with the objective of maximizing the after tax profit of an international corporation. The constraints mandated by the national taxing authorities create a bilinear programming formulation. We will describe a very efficient heuristic iterative solution algorithm, which alternates between the optimization of the transfer prices and the material flows. Performance and bounds for the heuristic algorithms will be discussed. The second model focuses on the production and distribution allocation in a single country system, when the customers have seasonal demands. This model also needs to be solved as a subproblem in the heuristic solution of the global transfer price model. The research develops an integrated design methodology based on primal decomposition methods for the mixed integer programming formulation. The primal decomposition allows a natural split of the production and transportation decisions and the research identifies the necessary information flows between the subsystems. The primal decomposition method also allows a very efficient solution algorithm for this general class of large mixed integer programming models. Data requirements and solution times will be discussed for a real life case study in the packaging industry. 2002 Elsevier Science B.V. All rights reserved. European Journal of Operational Research 143 (2002) 1–18 www.elsevier.com/locate/dsw * Corresponding author. Tel.: +1-404-894-2317; fax: +1-404-894-2301. E-mail address: marc.goetschalckx@isye.gatech.edu (M. Goetschalckx). 0377-2217/02/$ see front matter 2002 Elsevier Science B.V. All rights reserved. PII: S0377-2217 (02 )00142-X
Techniques and algorithms for fault grading of FPGA interconnect test configurations

Conventional fault simulation techniques for field programmable gate arrays (FPGAs) are very complicated and time consuming. The alternative, FPGA fault emulation technique, is incomplete and can be used only after the FPGA chip is manufactured. In this paper, we present efficient algorithms for computing the fault coverage of a given FPGA test configuration. The faults considered are opens and shorts in FPGA interconnects. The presented technique is able to report all detectable and undetectable faults and, compared with conventional methods, is orders of magnitude faster.
Safety and tolerability of immune globulin intravenous (human), 10% solution in Japanese subjects with mild to moderate Alzheimer's disease.

BACKGROUND
Immune globulin intravenous (IGIV), 10% is a donor-derived polyclonal human immunoglobulin G antibody mixture that has potent immune modulatory properties and contains conformation selective anti-amyloid antibodies. We evaluated the safety and tolerability of multiple doses of IGIV, 10% in Japanese patients with mild to moderate Alzheimer's disease.


METHODS
Among the 16 subjects, 12 subjects were assigned to the IGIV group and 4 subjects to the placebo group. Subjects received a total of six infusions of either IGIV at a dose of 0.2 or 0.4 g/kg, or placebo every 2 weeks.


RESULTS
A total of 33 treatment-emergent adverse events (TEAE) occurred in 14 subjects: 13 TEAE in five subjects in both the IGIV 0.2 and 0.4 g/kg groups, and 7 TEAE in four subjects in the placebo group. The most common TEAE in the IGIV subjects were nasopharyngitis, injection-site swelling, and erythema. All 26 TEAE in the IGIV group were considered to be mild. Only one mild TEAE (rash) was considered to be possibly related to the study drug. There were no significant differences in incidence of TEAE between the treatment groups. Four serious TEAE were reported, and all of these were considered to be unrelated to the study treatment. Other assessments related to safety revealed neither clinically significant abnormal values nor findings in the study.


CONCLUSION
IGIV is generally safe and well tolerated with multiple intravenous infusions at doses of 0.2 g/kg and 0.4 g/kg in Japanese patients with mild to moderate Alzheimer's disease.
THE SURVEY STUDY OF MATHEMATICS MOTIVATED STRATEGIES FOR LEARNING QUESTIONNAIRE (MMSLQ) FOR GRADE 10-12 TAIWANESE STUDENTS

This study draws attention in understanding senior high and vocational school students’ mathematics learning motivation and strategies. While Taiwan students have good mathematics performance in international competition but they have low confidence in learning mathematics well. Two questionnaires about motivation and learning strategies were developed based on Motivational Strategies for Learning Questionnaire (MSLQ), and were issued to 1,282 participants. The results show that the students have weak motivation and a less usage rate of learning strategies in learning mathematics. Besides, the result showed that the students went to cram school showed higher motivation for learning mathematics, and the students went to cram school also used learning strategies better than the students didn’t go to cram school. Also, male students showed higher motivation for learning mathematics, and male students also used learning strategies better than female students.
Effects of age-dependent membrane transport changes on the homeostasis of senescent human red blood cells

Little is known about age-related changes in red blood cell (RBC) membrane transport and homeostasis. We investigated first whether the known large variation in plasma membrane Ca(2+) (PMCA) pump activity was correlated with RBC age. Glycated hemoglobin, Hb A1c, was used as a reliable age marker for normal RBCs. We found an inverse correlation between PMCA strength and Hb A1c content, indicating that PMCA activity declines monotonically with RBC age. The previously described subpopulation of high-Na(+), low-density RBCs had the highest Hb A1c levels, suggesting it represents a late homeostatic condition of senescent RBCs. Thus, the normal densification process of RBCs with age must undergo late reversal, requiring a membrane permeability increase with net NaCl gain exceeding KCl loss. Activation of a nonselective cation channel, Pcat, was considered the key link in this density reversal. Investigation of Pcat properties showed that its most powerful activator was increased intracellular Ca(2+). Pcat was comparably selective to Na(+), K(+), choline, and N-methyl-D-glucamine, indicating a fairly large, poorly selective cation permeability pathway. Based on these observations, a working hypothesis is proposed to explain the mechanism of progressive RBC densification with age and of the late reversal to a low-density condition with altered ionic gradients.
Influence functions of the Spearman and Kendall correlation measures

Nonparametric correlation estimators as the Kendall and Spearman correlation are widely used in the applied sciences. They are often said to be robust, in the sense of being resistant to outlying observations. In this paper we formally study their robustness by means of their influence functions and gross-error sensitivities. Since robustness of an estimator often comes at the price of an increased variance, we also compute statistical efficiencies at the normal model. We conclude that both the Spearman and Kendall correlation estimators combine a bounded and smooth influence function with a high efficiency. In a simulation experiment we compare these nonparametric estimators with correlations based on a robust covariance matrix estimator.
A rapid and efficient way to manage hyponatremia in patients with SIADH and small cell lung cancer: treatment with tolvaptan

BACKGROUND
Hyponatremia based on syndrome of inappropriate antidiuretic hormone hypersecretion (SIADH) is observed in up to 15% of patients with small cell lung cancer (SCLC). The electrolyte imbalance is associated with a high morbidity and mortality and often delays appropriate treatment. Management of hyponatremia proved to be challenging until new vasopressin-2 receptor antagonists such as tolvaptan became available. This is the first report which presents a prospective case series with an efficient management of hyponatremia including tolvaptan in ten patients with SCLC and severe SIADH (plasma sodium < 125 mmol/l).


METHODS
Ten patients with SCLC and severe SIADH were followed after the onset of clinical symptoms of SIADH. Patients were chosen on the basis of histological proven diagnosis of SCLC and the clinical picture of a neurocognitive deficit caused by SIADH-related hyponatremia. All patient data were monitored for clinical improvement based on ECOG status, commencement of chemotherapy and correction of sodium levels.


RESULTS
The treatment followed a diagnostic and treatment algorithm and lead to a rapid and efficient correction of both clinical symptoms and plasma sodium level.


CONCLUSIONS
Based on this algorithm all patients started chemotherapy in time. Subsequently, the treatment with tolvaptan lead to an improvement of the ECOG-performance status. In addition, all patients benefit from the effective management of SIADH which omitted prolonged hospital stays and non-elective hospitalizations due to an unstable clinical condition due to severe hyponatremia. These observations add new insight to management of SIADH in thoracic oncology and are of interest for specialists in oncology, endocrinology and pulmonary medicine.
It won't happen to me: Promoting secure behaviour among internet users

Fraudulent activity on the Internet, in particular the practice known as ‘Phishing’, is on the increase. Although a number of technology focussed counter measures have been explored user behaviour remains fundamental to increased online security. Encouraging users to engage in secure online behaviour is difficult with a number of different barriers to change. Guided by a model adapted from health psychology this paper reports on a study designed to encourage secure behaviour online. The study aimed to investigate the effects of education via a training program and the effects of risk level manipulation on subsequent self-reported behaviour online. The training program ‘Anti-Phishing Phil’ informed users of the common types of phishing threats and how to identify them whilst the risk level manipulation randomly allocated participants to either high risk or low risk of becoming a victim of online fraud. Sixty-four participants took part in the study, which comprised of 9 males and 55 females with an age range of 18– 43 years. Participants were randomly allocated to one of four experimental groups. High threat information and/or the provision of phishing education were expected to increase self-reports of secure behaviour. Secure behaviour was measured at three stages, a baseline measure stage, an intention measure stage, and a 7-day follow-up measure stage. The results showed that offering a seemingly tailored risk message increased users’ intentions to act in a secure manner online regardless of whether the risk message indicated they were at high or low risk of fraud. There was no effect of the training programme on secure behaviour in general. The findings are discussed in relation to the model of behaviour change, information provision and the transferability of training. 2010 Elsevier Ltd. All rights reserved.
Beyond anonymity, or future directions for internet identity research

This article draws on empirical research into internet use by minority ethnic women to consider whether anonymity remains a useful focus for sociocultural studies of internet identities. The central argument of the article is that the time has come for internet identity research to reposition itself conceptually, to move away from a preoccupation with the generalized, enduring claim that internet identities are anonymous, multiple and fragmented – not only because, in some cases, online identities are continuous with offline selves, but also, more importantly, because common uses of the concept of anonymity are limited as starting points for carrying out analyses of internet experiences. In short, it argues that the terms of internet identity research are problematic, that contexts matter, and that studies of internet identities need to engage with and learn from ongoing debates within cultural studies which call into question the usefulness of the very concept of identity.