LLukas22/scidocs huggingface dataset:
The prognostic value of pre-discharge exercise testing after myocardial infarction treated with either primary PCI or fibrinolysis: a DANAMI-2 sub-study.

AIMS
To evaluate the prognostic importance of pre-discharge maximal symptom-limited exercise testing (ET) following acute myocardial infarction (AMI) in the era of aggressive reperfusion.


METHODS AND RESULTS
In the DANAMI-2 (the second DANish trial in AMI) study, patients with ST-elevation AMI (STEMI) were randomized to primary angioplasty (PCI) or fibrinolysis. Of 1462 patients discharged alive, 1164 (79.6%) performed an ET. Primary endpoint was a composite of death and re-infarction. Patients randomized to fibrinolysis developed ST-depression to a greater extent than patients randomized to primary PCI (21.7 vs. 15.3%, P=0.007). Multivariable predictors of death and re-infarction included age, gender, diabetes, previous stroke, anterior AMI, randomization to fibrinolysis, and exercise capacity [risk ratio (RR) 0.82 (0.72-0.93); P<0.001]. ST-depression was predictive of the clinical outcome [RR 1.57 (1.00-2.48); P<0.05] in multivariable analysis, but stratified according to treatment groups there was a significant association between ST-depression and outcome in the fibrinolysis group [RR 1.95 (1.11-3.44); P<0.05], but not in the primary PCI group [RR 1.06 (0.47-2.36); P=ns]. However, the P-value for interaction was 0.15.


CONCLUSION
Exercise testing after contemporary reperfusion therapies for STEMI confers important prognostic information. Exercise capacity is a strong prognostic predictor of death and re-infarction irrespective of treatment strategy, whereas the prognostic significance of ST-depression seems to be strongest in the fibrinolysis-treated patients.
Weber, Habermas, and transformations of the European state : constitutional, social, and supranational democracy

1. Introduction: theorizing modern transformations of law and democracy 2. The historical logic(s) of Habermas's critique of Weber's 'sociology of law' 3. The puzzle of law, democracy and historical change in Weber's 'sociology of law' 4. Habermas's deliberatively legal Sozialstaat 5. Habermas on the European Union: normative aspirations 6. The structural transformation to the supranational Sektoralstaat and prospects for democracy in the EU 7. Conclusion: Habermas's philosophy of history and the future of Europe.
In-hand precise twisting and positioning by a novel dexterous robotic gripper for industrial high-speed assembly

In electronic manufacturing system, the design of the robotic hand with sufficient dexterity and configuration is important for the successful accomplishment of the assembly task. Due to the growing demand from high-mix manufacturing industry, it is difficult for the traditional robot to grasp a large number of assembly parts or tools having cylinder shapes with correct postures. In this research, a novel jaw like gripper with human-sized anthropomorphic features is designed for in-hand precise positioning and twisting online. It retains the simplicity feature of traditional industrial grippers and dexterity features of dexterous grippers. It can apply a constant gripping force on assembly parts and performs reliable twisting movement within limited time to meet the industrial requirements. Manipulating several cylindrical assembly parts by robot, as an experimental case in this paper, is studied to evaluate its performance. The effectiveness of proposed gripper design and mechanical analysis is proved by the simulation and experimental results.
Online estimation of model parameters and state-of-charge of Lithium-Ion battery using Unscented Kalman Filter

For the operation of Autonomous Mobile Robot (AMR) in unknown environments, accurate estimation of internal parameters and consequently precise prediction of the battery state of charge (SoC) are critical issues for power management. Battery performance can be affected by factors such as temperature deviation, discharge/charge current, Coulombic efficiency losses, and aging. Thus, in order to increase the model accuracy, it is important to update the model parameters online. In this paper, the Unscented Kalman Filter (UKF) is employed for the online estimation of the Lithium-Ion battery model parameters and the battery SoC based on the updated model. The proposed method is evaluated experimentally, and the results are compared with that of the Extended Kalman Filter (EKF). The comparison with the EKF shows that UKF provides better accuracy both in battery parameters estimation and the battery SoC estimation.
Detection of viable Escherichia coli O157:H7 in ground beef by propidium monoazide real-time PCR.

Escherichia coli O157:H7 associated with food has caused many serious public health problems in recent years. However, only viable cells of this pathogen can cause infections, and false-positive detection caused by dead cells can lead to unnecessary product recalls. The objective of this study was to develop and optimize a method that combines propidium monoazide (PMA) staining with real-time PCR to detect only viable cells of E. coli O157:H7 in ground beef. PMA is a DNA intercalating dye that can penetrate compromised membranes of dead cells and bind to cellular DNA, preventing its amplification via a subsequent PCR. Three strains of E. coli O157:H7 (505B, G5310 and C7927) at concentrations of 10(0) to 10(8)CFU/mL were used as live cells. Dead cells were obtained by heating cell suspensions at 85°C for 15 min. Suspensions were treated with PMA and the optimized assay was applied to artificially contaminated ground beef with two different fat contents (10% and 27%). DNA was extracted and amplified by TaqMan® real-time PCR assay targeting the uidA gene for detection of E. coli O157:H7. Plasmid pUC19 was added as an internal amplification control (IAC). A treatment of 25 μM PMA with a 10-min light exposure on ice was sufficient to eliminate DNA from 10(8) dead E. coli O157:H7 cells/mL. The optimized assay could detect as low as 10(2) CFU/mL viable E. coli O157:H7 in pure culture and 10(5) CFU/g in ground beef, in the presence of 10(6)/mL or g of dead cells. With an 8-h enrichment, 1 CFU/g viable E. coli O157:H7 in ground beef was detectable without interference from 10(6) dead cells/g. In conclusion, the PMA real-time PCR could effectively detect viable E. coli O157:H7 without being compromised by dead cells.
Mooshak: a Web-based multi-site programming contest system

This paper presents a new Web-based system, Mooshak, to handle programming contests. The system acts as a full contest manager as well as an automatic judge for programming contests. Mooshak innovates in a number of aspects: it has a scalable architecture that can be used from small single server contests to complex multi-site contests with simultaneous public online contests and redundancy; it has a robust data management system favoring simple procedures for storing, replicating, backing up data and failure recovery using persistent objects; it has automatic judging capabilities to assist human judges in the evaluation of programs; it has built-in safety measures to prevent users from interfering with the normal progress of contests. Mooshak is an open system implemented on the Linux operating system using the Apache HTTP server and the Tcl scripting language. This paper starts by describing the main features of the system and its architecture with reference to the automated judging, data management based on the replication of persistent objects over a network. Finally, we describe our experience using this system for managing two official programming contests. Copyright c © 2003 John Wiley & Sons, Ltd.
Trading Consequences: A Case Study of Combining Text Mining & Visualisation to Facilitate Document Exploration

Large-scale digitization efforts and the availability of computational methods, including text mining and information visualization, have enabled new approaches to historical research. However, we lack case studies of how these methods can be applied in practice and what their potential impact may be. Trading Consequences is an interdisciplinary research project between environmental historians, computational linguists and visualization specialists. It combines text mining and information visualization alongside traditional research methods in environmental history to explore commodity trade in the nineteenth century from a global perspective. Along with a unique data corpus, this project developed three visual interfaces to enable the exploration and analysis of four historical document collections, consisting of approximately 200,000 documents and 11 million pages related to commodity trading. In this paper we discuss the potential and limitations of our approach based on feedback from historians we elicited over the course of this project. Informing the design of such tools in the larger context of digital humanities projects, our findings show that visualization-based interfaces are a valuable starting point to large-scale explorations in historical research. Besides providing multiple visual perspectives on the document collection to highlight general patterns, it is important to provide a context in which these patterns occur and offer analytical tools for more in-depth investigations.
Translucency of dental ceramics with different thicknesses.

STATEMENT OF PROBLEM
The increased use of esthetic restorations requires an improved understanding of the translucent characteristics of ceramic materials. Ceramic translucency has been considered to be dependent on composition and thickness, but less information is available about the translucent characteristics of these materials, especially at different thicknesses.


PURPOSE
The purpose of this study was to investigate the relationship between translucency and the thickness of different dental ceramics.


MATERIAL AND METHODS
Six disk-shaped specimens of 8 glass ceramics (IPS e.max Press HO, MO, LT, HT, IPS e.max CAD LT, MO, AvanteZ Dentin, and Trans) and 5 specimens of 5 zirconia ceramics (Cercon Base, Zenotec Zr Bridge, Lava Standard, Lava Standard FS3, and Lava Plus High Translucency) were prepared following the manufacturers' instructions and ground to a predetermined thickness with a grinding machine. A spectrophotometer was used to measure the translucency parameters (TP) of the glass ceramics, which ranged from 2.0 to 0.6 mm, and of the zirconia ceramics, which ranged from 1.0 to 0.4 mm. The relationship between the thickness and TP of each material was evaluated using a regression analysis (α=.05).


RESULTS
The TP values of the glass ceramics ranged from 2.2 to 25.3 and the zirconia ceramics from 5.5 to 15.1. There was an increase in the TP with a decrease in thickness, but the amount of change was material dependent. An exponential relationship with statistical significance (P<.05) between the TP and thickness was found for both glass ceramics and zirconia ceramics.


CONCLUSIONS
The translucency of dental ceramics was significantly influenced by both material and thickness. The translucency of all materials increased exponentially as the thickness decreased. All of the zirconia ceramics evaluated in the present study showed some degree of translucency, which was less sensitive to thickness compared to that of the glass ceramics.
Offender Profiling And Criminal Differentiation

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Stochastic conservation laws

Abstract We examine conservation laws, typically the conservation of linear momentum, in the light of a recent successful formulation of fermions as Kerr–Newman type Black Holes, which are created fluctuationally from a background Zero Point Field as in Prigogine's cosmology also. We conclude that these conservation laws are to be taken in the spirit of thermodynamic laws.
Intramuscular ketamine for pediatric sedation in the emergency department: safety profile in 1,022 cases.

STUDY OBJECTIVE
To determine the safety of intramuscular ketamine when administered by emergency physicians for pediatric procedures in accordance with a defined protocol.


METHODS
We assembled a consecutive case series of children aged 15 years or younger who were given ketamine in the emergency departments of a university medical center and an affiliated county hospital over a 9-year period. A protocol for ketamine use (4 mg/kg, intramuscularly) was followed. Treating physicians were instructed to complete data forms recording complications and adequacy of sedation concurrent with patient care. Subsequent chart review was used to determine indications, adjunctive drugs, time to discharge, and adverse reactions for all patients.


RESULTS
Intramuscular ketamine was administered 1,022 times, mainly for laceration repair and fracture reduction. Physicians completed data forms for 431 of treated children (42%). Transient airway complications occurred in 1.4%: airway malalignment (n = 7), laryngospasm (n = 4), apnea (n = 2), and respiratory depression (n = 1). All were quickly identified and treated without intubation or sequelae. Emesis occurred in 6.7%, without evidence of aspiration. Mild recovery agitation occurred in 17.6%, moderate to severe agitation in 1.6%. No child required hospitalization for complications caused by ketamine. Ketamine produced acceptable sedation in 98% of patients. The median time from injection to emergency department discharge was 110 minutes for children given a single dose of ketamine.


CONCLUSION
Intramuscular ketamine may be administered safely by emergency physicians to facilitate pediatric procedures in accordance with a defined protocol and with appropriate monitoring. Ketamine is highly effective, has a wide margin of safety, does not require intravenous access, and uniquely preserves protective airway reflexes.
The aging hand.

Hand function decreases with age in both men and women, especially after the age of 65 years. A review is presented of anatomical and physiological changes in the aging hand. The age-related changes in prehension patterns (grip and pinch strength) and hand dexterity in the elderly population are considered. Deterioration in hand function in the elderly population is, to a large degree, secondary to age-related degenerative changes in the musculoskeletal, vascular, and nervous systems. Deterioration of hand function in elderly adults is a combination of local structural changes (joints, muscle, tendon, bone, nerve and receptors, blood supply, skin, and fingernails) and more distant changes in neural control. These age-related changes are often accompanied by underlying pathological conditions (osteoporosis, osteoarthritis, rheumatic arthritis, and Parkinson's disease) that are common in the elderly population. Assessment of hand function and prehension patterns is needed in order to determine specific treatment approaches.
Emotional intelligence and its association with orgasmic frequency in women.

INTRODUCTION
Up to 30% of women suffer from female orgasmic disorder (FOD)-the second most common type of female sexual dysfunction. FOD has been acknowledged to be multifactorial and recent research has implicated the importance of psychosocial risk factors.


AIM
The aim of this study is to investigate whether normal variations in emotional intelligence--the ability to identify and manage emotions of one's self and others--are associated with orgasmic frequency during intercourse and masturbation. To our knowledge, this is the first such study in a large unselected population.


METHODS
A total of 2035 women from the TwinsUK registry completed questionnaires relating to emotional intelligence and sexual behavior. Global emotional intelligence was measured using the Trait Emotional Intelligence Questionnaire-Short Form (TEIQue-SF). Orgasmic frequency was assessed using two self-constructed questions.


MAIN OUTCOME MEASURES
Using Spearman's rank correlation and quartile logistic regression, we investigated whether variations in emotional intelligence are associated with female orgasmic frequency during intercourse and masturbation.


RESULTS
Emotional intelligence was not associated with the potential confounders of age and years of education, nor did we find a significant association between emotional intelligence and potential risk factors for FOD such as age, body mass index, physical or sexual abuse, or menopause. We found emotional intelligence to be positively correlated with both frequency of orgasm during intercourse (r = 0.13, P < 0.001) and masturbation (r = 0.23, P < 0.001). Women in the lowest quartile of emotional intelligence had an approximate twofold increased risk of infrequent orgasm (Intercourse = odds ratio [OR] 2.3, 95% confidence interval [CI] 1.4-3.9; Masturbation = [OR] 1.8, [CI] 1.3-2.5).


CONCLUSION
Low emotional intelligence seems to be a significant risk factor for low orgasmic frequency. Consideration of this behavioral risk factor may need to be incorporated into research into FOD and possible treatment approaches.
Changes in health-related quality of life after ultrasound-guided foam sclerotherapy for great and small saphenous varicose veins.

BACKGROUND
Health-related quality of life (HRQOL) improves after superficial venous surgery for varicose veins, but the effect of ultrasound-guided foam sclerotherapy on HRQOL is unknown. The aim of this study was to determine changes in HRQOL after ultrasound-guided foam sclerotherapy for varicose veins.


METHODS
Consecutive patients undergoing ultrasound-guided foam sclerotherapy for varicose veins were sent the Short Form 12 (SF-12) questionnaire, a generic measure of HRQOL, and the Aberdeen Varicose Vein Symptom Score (AVSS) questionnaire, a disease-specific measure of HRQOL, 1 week before treatment and 1, 6, and 12 months after treatment.


RESULTS
The study enrolled 296 patients (34% male; 395 treated legs) with a median age of 57 years (range, 22-89 years). Of these, 24% had had previous superficial venous surgery, and 66% were CEAP C(2-3) (uncomplicated varicose veins). Questionnaire completion rates were 82%, 73%, and 69% at 1, 6, and 12 months after treatment. The median Physical Component Summary score of the SF-12 (higher score indicates better HRQOL) improved from 47.6 pretreatment to 49.4 at 1 month (P < .008, Wilcoxon signed rank test), to 51.9 at 6 months (P < .0005), and to 52.9 at 12 months (P < .0005). The median AVSS (lower score indicates better HRQOL) improved from 19.0 pretreatment to 16.5 at 1 month (P < .0005), to 8.7 at 6 months (P < .0005), and to 8.6 at 12 months (P < .0005).


CONCLUSIONS
Ultrasound-guided foam sclerotherapy for great and small saphenous varicose veins leads to significant improvements in generic and disease-specific HRQOL for at least 12 months after treatment.
The impacts of perceived organizational support and psychological empowerment on job performance: the mediating effects of organizational citizenship behavior.

Hotels are under constant pressure from the need to compete, not just the need to respond to rapid changes in the market. Hotels, moreover, must inspire their employees to perform their best and encourage employees to fulfill their responsibilities as citizens. Academia and industry recognize the importance of organizational citizenship behavior. This study assessed how hotel employees perceive organizational support, psychological empowerment, organizational citizenship behavior, and job performance; and examined the causal relationships among these variables. A total of 513 employees of Taiwan hotels participated in the study. Data was analyzed through descriptive statistics, confirmatory factor analysis, and the structural equation modeling. Results indicated that perceived organizational support and psychological empowerment both positively affected organizational citizenship behavior. Perceived organizational support did not positively influence job performance. Psychological empowerment and organizational citizenship behavior positively influenced job performance. Organizational behavior acted as a partial mediator between perceived organizational support and job performance, as well as between psychological empowerment and job performance. A number of suggestions on theory and managerial implementation were proposed. © 2011 Elsevier Ltd. All rights reserved.
Estimate of the national incidence of and operation-level risk factors for colic among horses in the United States, spring 1998 to spring 1999.

OBJECTIVE
To estimate the national incidence of, operation-level risk factors for, and annual economic impact of colic among horses in the United States during 1998 and 1999.


DESIGN
Epidemiologic survey.


ANIMALS
21,820 horses on 1,026 horse operations in 28 states.


PROCEDURES
Horses were monitored for colic for 1 year, and results were recorded in a log that was collected quarterly. Operation-level data were collected via 4 on-site personal interviews. Associations between colic and independent variables adjusted for size of operation were determined.


RESULTS
Annual national incidence of colic in the US horse population was estimated to be 4.2 colic events/100 horses per year. Case fatality rate was 11%, and 1.4% of colic events resulted in surgery. Annual cost of colic in the United States was estimated to be $115,300,000.


CONCLUSIONS AND CLINICAL RELEVANCE
The national impact of equine colic is substantial because of the high case fatality rate.
A high-intensity lumbar extensor strengthening program is little better than a low-intensity program or a waiting list control group for chronic low back pain: a randomised clinical trial.

QUESTION
Is eight weeks of high-intensity strengthening of the isolated lumbar extensors more effective than low-intensity strengthening or no strengthening? Are any gains maintained 16 weeks later?


DESIGN
Randomised, three-arm trial with concealed allocation, assessor blinding, and intention-to-treat-analysis. Participants in the waiting list control group were randomised again, after the first 8 weeks, to either the high-intensity or the low-intensity strengthening program.


PARTICIPANTS
Sixty-five army personnel with non-specific chronic low back pain.


INTERVENTION
The high-intensity training group received 10 sessions of 15 to 20 repetitions for the isolated lumbar extensor muscles. The low-intensity training group received a nonprogressive, low-intensity resistance protocol.


OUTCOME MEASURES
Primary outcomes were global perceived effect and disability. Secondary outcomes were health-related quality of life, fear of movement/(re-)injury, and isometric lumbar extensor muscle strength. Measures were taken before and after the training and 16 weeks later.


RESULTS
At eight weeks, SF-36 overall score was on average 7% (95% CI 1 to 13) greater in the high-intensity training group compared with the low-intensity training group and the waiting list control group, and self-assessed decrease of back symptoms was on average 39% (95% CI 14 to 64) greater in the high-intensity training group compared with the waiting list control group. There was no difference in improvement between the groups for any other outcome at 8 weeks or 24 weeks.


CONCLUSIONS
Although some beneficial effects were found, the results of this high-intensity strengthening program of the isolated lumbar extensor muscles do not clearly support the generally-claimed beneficial influence of exercise for chronic non-specific low back pain.