LLukas22/scidocs huggingface dataset:
Caching Techniques for Streaming Multimedia over the Internet

Existing solutions for streaming multimedia in the Internet do not scale in terms of object size and number of supported streams. Using separate unicast streams, for example, will overload both network and servers. While caching is the standard technique for improving scalability, existing caching schemes do not support streaming media well. In this paper, we propose a complete solution for caching multimedia streams in the Internet by extending existing techniques and proposing new techniques to support streaming media. These include segmentation of streaming objects, dynamic caching, and self-organizing cooperative caching. We consider these techniques in an integrated fashion. We implemented a complete caching architecture called SOCCER using the network simulator ns-2 and evaluate the effectiveness of each proposed technique and compare them to alternative caching solutions. Keywords—Streaming Media, Caching, Proxy.
SocialFilter: Introducing social trust to collaborative spam mitigation

We propose SocialFilter, a trust-aware collaborative spam mitigation system. Our proposal enables nodes with no email classification functionality to query the network on whether a host is a spammer. It employs Sybil-resilient trust inference to weigh the reports concerning spamming hosts that collaborating spam-detecting nodes (reporters) submit to the system. It weighs the spam reports according to the trustworthiness of their reporters to derive a measure of the system's belief that a host is a spammer. SocialFilter is the first collaborative unwanted traffic mitigation system that assesses the trustworthiness of spam reporters by both auditing their reports and by leveraging the social network of the reporters' administrators. The design and evaluation of our proposal offers us the following lessons: a) it is plausible to introduce Sybil-resilient Online-Social-Network-based trust inference mechanisms to improve the reliability and the attack-resistance of collaborative spam mitigation; b) using social links to obtain the trustworthiness of reports concerning spammers can result in comparable spam-blocking effectiveness with approaches that use social links to rate-limit spam (e.g., Ostra [27]); c) unlike Ostra, in the absence of reports that incriminate benign email senders, SocialFilter yields no false positives.
Quantitative IT portfolio management

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CliNER : A Lightweight Tool for Clinical Named Entity Recognition

Introduction Named entity recognition (NER) is essentially a solved problem for information extraction in the general domain, with an abundance of both the systems and the annotated data. Clinical domain has been lagging behind, with many existing systems (including cTAKES, for example) relying nearly exclusively on UMLS-based dictionary lookup. Despite the recent advances in clinical concept extraction, spurred by such community-wide initiatives as the 2010 i2b2 shared task, no lightweight, easy to set up, open-source implementation is available to date. General domain systems cannot be adapted directly to clinical data, since clinical concepts require domain-specific features, including those using specialized knowledge sources. The point of the shared tasks has been generate publicly available annotated data and to identify best-performing methods, which has helped to push forward the state of the art in the clinical-domain information extraction. At the same time, the format of the workshops has not allowed or encouraged the participants to develop fully functioning, user-friendly systems. Many of the systems developed during the shared task challenges or published subsequently are never released for public use , and frequently are put together haphazardly from opportunistically developed code components. On the other hand, the available systems developed outside of the shared task paradigm tend to be heavy aggregations of multiple components that require extensive set up and configuration, which presents a significant barrier to initial use.
The role of small cell technology in future Smart City applications

Meeting citizens’ requirements economically and efficiently is the most important objective of Smart Cities. As a matter of fact, they are considered a key concept both for future Internet and information and communications technology. It is expected that a wide range of services will be made available for residential users (e.g. intelligent transportation systems, e-government, e-banking, e-commerce and smart management of energy demand), public administration entities, public safety and civil protection agencies and so on with increased quality, lower costs and reduced environmental impact. In order to achieve these ambitious objectives, new technologies should be developed such as non-invasive sensing, highly parallel processing, smart grids and mobile broadband communications. This paper considers the communication aspects of Smart City applications, specifically, the role of the latest developments of Long-Term Evolution-Advanced standard, which forecast the increase of broadband coverage by means of small cells. We shall demonstrate that the novel concept of small cell fully meets the emerging communication and networking requirements of future Smart Cities. To this aim, a feasible network architecture for future Smart Cities, based on small cells, will be discussed in the framework of a future smarter and user-centric perspective of forthcoming 4G mobile technologies. Copyright © 2013 John Wiley & Sons, Ltd.
Factors that Affect Accounting Information System Implementation and Accounting Information Quality : A Survey in University Utara Malaysia

The purpose of this study is to investigate factors that affect accounting information system implementation and accounting informat ion quality from Universit i Utara Malaysia student’s points of view. It examines the effect of human resources, data quality and management commitment on accounting information system and information quality. A survey of 119 respondents is selected to gather information’s to test the study hypotheses. The main findings indicate that there is significant relationship between management commitments, data quality and accounting information system. However, the relation is not significantly related to human resources. Furthermore, the relat ion between management commitment and data quality are not significantly related to accounting informat ion quality but significantly related to accounting information system and human resources. The study recommends that comprehensive training programmes to get the sufficient knowledge in accounting informat ion system implementation and the importance of data quality, furthermore, top management should support AIS implementation to get full benefit of accounting information system.
CLAUDETTE: an automated detector of potentially unfair clauses in online terms of service

Terms of service of on-line platforms too often contain clauses that are potentially unfair to the consumer. We present an experimental study where machine learning is employed to automatically detect such potentially unfair clauses. Results show that the proposed system could provide a valuable tool for lawyers and consumers alike.
Cognitive change in donepezil treated patients with vascular or mixed dementia.

BACKGROUND
vascular dementia (VaD) and mixed Alzheimer's disease (AD/VaD) are common. How best to monitor treatment is not clear. Our objective was to compare responsiveness and construct validity of change scores, following donepezil treatment, of the standardized Mini-Mental State Examination (sMMSE) and other measures potentially usable in primary care.


METHODS
A six-month, outcome measurement study. The Disability Assessment for Dementia (DAD), CLOX-1 and 2, Phonetic Fluency, a short Neuropsychiatric Inventory, (the NPI-Q), Clinical Global Impression (CGI) and the SymptomGuide™ (SG) were measured. Construct validity was tested by correlating change scores, and responsiveness by calculating standardized response means (SRMs).


RESULTS
Of 148 treated patients, 116 completed. The mean sMMSE increased by 0.7 (95% Confidence Interval (CI) = -0.005, 1.41; p=0.06; SRM= 0.15). There was no statistically significant difference in the DAD. The NPI-Q (-1.4; 95% CI = -2.08, -0.72; p<0.01; SRM=0.24), CLOX-1 (0.9; 95% CI = 0.19, 1.61; p<0.01; SRM=0.21), CLOX-2 (0.9; 95% CI = 0.17, 1.63; p=0.03; SRM=0.26), Phonetic Fluency (0.9; 95% CI = 0.19, 1.61; p=0.02; SRM=0.21) and SG (0.35; 95% CI = 0.20,0.51; p<0.01; SRM=0.28) each detected significant improvement. The CGI suggested improvement in 74 completers (64%) - mostly "minimal" (44/116, 38%) - while 21/116 (18%) were worse. Change scores at 24 weeks were at best modestly correlated with each other (range -0.22 to 0.30).


DISCUSSION
Different measures showed different responsiveness, in a setting in which the mean treatment effect seems to have been small, but clinically detectable. Patient-centered and executive function measures might be useful in vascular and mixed dementia.
Acetabular distraction: an alternative for severe defects with chronic pelvic discontinuity?

BACKGROUND
Stabilization of a pelvic discontinuity with a posterior column plate with or without an associated acetabular cage sometimes results in persistent micromotion across the discontinuity with late fatigue failure and component loosening. Acetabular distraction offers an alternative technique for reconstruction in cases of severe bone loss with an associated pelvic discontinuity.


QUESTIONS/PURPOSES
We describe the acetabular distraction technique with porous tantalum components and evaluate its survival, function, and complication rate in patients undergoing revision for chronic pelvic discontinuity.


METHODS
Between 2002 and 2006, we treated 28 patients with a chronic pelvic discontinuity with acetabular reconstruction using acetabular distraction. A porous tantalum elliptical acetabular component was used alone or with an associated modular porous tantalum augment in all patients. Three patients died and five were lost to followup before 2 years. The remaining 20 patients were followed semiannually for a minimum of 2 years (average, 4.5 years; range, 2-7 years) with clinical (Merle d'Aubigné-Postel score) and radiographic (loosening, migration, failure) evaluation.


RESULTS
One of the 20 patients required rerevision for aseptic loosening. Fifteen patients remained radiographically stable at last followup. Four patients had early migration of their acetabular component but thereafter remained clinically asymptomatic and radiographically stable. At latest followup, the average improvement in the patients not requiring rerevision using the modified Merle d'Aubigné-Postel score was 6.6 (range, 3.3-9.6). There were no postoperative dislocations; however, one patient had an infection, one a vascular injury, and one a bowel injury.


CONCLUSIONS
Acetabular distraction with porous tantalum components provides predictable pain relief and durability at 2- to 7-year followup when reconstructing severe acetabular defects with an associated pelvic discontinuity.


LEVEL OF EVIDENCE
Level IV, therapeutic study. See Instructions for Authors for a complete description of levels of evidence.
Multiple-input modified inverse Watkins-Johnson converter without coupled inductors

A new multiple-input dc-dc converter realized from a modified inverse Watkins-Johnson topology is presented and analyzed. Fundamental electrical characteristics are presented and power budget equations are derived. Small signal analysis model of the propose converter is presented and studied. Two possible operation methods to achieve output voltage regulation are presented here. The analysis is verified with simulations and experiments on a prototype circuit.
Design and participant baseline characteristics of 'A Clinical Trial of IntensiVE Dialysis': the ACTIVE Dialysis Study.

AIMS
Observational reports suggest extended dialysis hours are associated with improved outcomes. These findings are confounded by better prognostic characteristics among people practising extended hours. The aim of this article is to provide an overview of the methods and baseline characteristics for ACTIVE Dialysis Study participants.


METHODS
This multicentre, randomized, open-label, blinded endpoint-assessment trial randomized participants receiving maintenance haemodialysis therapy to either extended (≥24 h) or standard (12-18 h) weekly haemodialysis for 12 months. A web-based randomization system used minimization to ensure balanced allocation across regions, dialysis setting and dialysis vintage. The primary outcome is the change in quality of life over 12 months of study treatment assessed by EQ-5D. Secondary outcomes include change in left ventricular mass index assessed by magnetic resonance imaging and safety outcomes including dialysis access events.


RESULTS
A total of 200 participants were recruited between 2009 and 2013 from Australia (29.0%), China (62.0%), Canada (5.5%) and New Zealand (3.5%). Participants had a mean age of 52 (± 12) years and 11.5% were dialysing at home, with a mean duration of 13.9 h per week over a median of three sessions. At baseline, 32.5% had a history of cardiovascular disease and 36.5% had diabetes.


CONCLUSION
The ACTIVE Dialysis Study has met its planned recruitment target. The participant population are drawn from a range of health service settings in a global context. The study will contribute important evidence on the benefits and harms of extending weekly dialysis hours. The trial is registered at clinicaltrials.gov (NCT00649298).
GNB5 Mutations Cause an Autosomal-Recessive Multisystem Syndrome with Sinus Bradycardia and Cognitive Disability.

GNB5 encodes the G protein β subunit 5 and is involved in inhibitory G protein signaling. Here, we report mutations in GNB5 that are associated with heart-rate disturbance, eye disease, intellectual disability, gastric problems, hypotonia, and seizures in nine individuals from six families. We observed an association between the nature of the variants and clinical severity; individuals with loss-of-function alleles had more severe symptoms, including substantial developmental delay, speech defects, severe hypotonia, pathological gastro-esophageal reflux, retinal disease, and sinus-node dysfunction, whereas related heterozygotes harboring missense variants presented with a clinically milder phenotype. Zebrafish gnb5 knockouts recapitulated the phenotypic spectrum of affected individuals, including cardiac, neurological, and ophthalmological abnormalities, supporting a direct role of GNB5 in the control of heart rate, hypotonia, and vision. LODDER, Elisabeth M, DE NITTIS, Pasquelena, KOOPMAN, Charlotte D & Collaboration, FISH, Richard (Collab.), et al. GNB5 Mutations Cause an Autosomal-Recessive Multisystem Syndrome with Sinus Bradycardia and Cognitive Disability. American Journal of Human Genetics, 2016, vol. 99, no. 3, p. 704-710
Retention of paclitaxel in cancer cells for 1 week in vivo and in vitro

Purpose: Clinically, the administration of paclitaxel for ovarian cancer on a dose-dense weekly schedule, rather than the conventional every-3-week schedule, might demonstrate greater tumor-cell death. Here, we investigate the pharmacokinetics and the pharmacodynamics of weekly paclitaxel in cancer cells in vivo and in vitro. Experimental design: Paclitaxel concentrations were measured by HPLC, and apoptotic cells were detected by TUNEL assay in paclitaxel-pretreated cervical cancer cells treated with paclitaxel (10 ng/ml) and in the tissues of cervical cancer patients treated with weekly paclitaxel (60 mg/m2/week). Polymerized tubulin was detected with a tubulin polymerization assay, and the BrdU cell proliferation assay was used to assess the effect of paclitaxel. Results: Paclitaxel remained in the cancer tissues of six patients for 6 days after the last medication. In vitro, paclitaxel was retained in all cell lines for 24 h after its removal from the medium, and paclitaxel was still detectable in CaSki cells on day 7. Simultaneous treatment with depolymerizing drugs inhibited the retention of paclitaxel in cells and paclitaxel-induced polymerization of tubulin. After paclitaxel treatment, apoptotic cells were detected in cancer tissues and CaSki cells for 1 week. Under high magnification, apoptotic cells on day 7 after paclitaxel treatment showed multinucleation. Conclusions: Paclitaxel is unusual in that it accumulates especially in cancer cells and induces apoptosis for 1 week in vivo and in vitro. On the other hand, paclitaxel could not be detected in cancer tissues after 2 weeks. The administration of paclitaxel on a weekly schedule, rather than the standard every-3-week schedule, might produce greater tumor-cell death.
ACTIVE APPEARANCE MODEL AND PCA BASED FACE RECOGNITION SYSTEM

At present face recognition has wide area of applications such as security, law enforcement. Imaging conditions, Orientation, Pose and presence of occlusion are huge problems associated with face recognition. The performance of face recognition systems decreases due to these problems. Discriminant Analysis (LDA) or Principal Components Analysis (PCA) is used to get better recognition results. Human face contains relevant information that can extracted from face model developed by PCA technique. Principal Components Analysis method uses eigenface approach to describe face image variation. A face recognition technique that is robust to all situations is not available. Some techniques are better in case of illumination, some for pose problem and some for occlusion problem. This paper presents some algorithms for face recognition. We discuss how greater accuracy can be achieved by extracting features from the boundaries of the faces by using Active Shape Models and, the skin textures, using Active Appearance Models, originally proposed by Cootes and Talyor. Index Terms Eigenfaces, face recognition, Active shape models, PCA. J.Savitha et al, International Journal of Computer Science and Mobile Computing, Vol.4 Issue.4, April2015, pg. 722-731 © 2015, IJCSMC All Rights Reserved 723
SAGE: system for algebra and geometry experimentation

SAGE is a framework for number theory, algebra, and geometry computation that is initially being designed for computing with elliptic curves and modular forms. The current implementation is primarily due to William Stein. It is open source and freely available under the terms of the GNU General Public License (GPL).
Heart Rate Variability Extraction From Videos Signals: ICA vs. EVM Comparison

Medical researchers have always been interested in heart rate (HR) and heart rate variability (HRV) analysis. However, nowadays, investigators from a variety of other fields are also probing the subject. Recent advancements in non-contact HR and HRV measurement techniques will likely further boost interest in emotional estimation through HRV. Such measurement methods involve the extraction of the photoplethysmography (PPG) signal from the human’s face through a camera. The latest approaches apply independent component analysis (ICA) on the color channels of video recordings to extract a PPG signal. Other investigated methods rely on Eulerian video magnification (EVM) to detect subtle changes in skin color associated with the PPG. To the best of our knowledge, EVM has not been successfully employed to extract HRV features from a video of a human face. In this paper, we present a comparison between our two approaches, one which is based on the ICA and the other is based on EVM. Final results show that the proposed ICA-based method yields better results when it comes to the high frequency (HF) and low frequency over high-frequency (LF/HF) HRV parameters [mean absolute error (MAE) of 0.57 and 0.419] when compared with the EVM-based method (MAE 0.76 and 1.69); however, the second method showed better MAE results for low frequency (LF) and higher correlation with the ground truth. Also our proposed ICA method showed better results in general by improving HF estimates, but the EVM-based method might be more appropriate when motion is involved or when the HF component is not important.
Update on the Family Strain Questionnaire: A Tool for the General Screening of Caregiving-Related Problems

Background: The growing prevalence of chronic diseases and home-based treatments has led to the introduction of a large number of instruments for assessing the caregiving-related problems associated with specific diseases, but our Family Strain Questionnaire (FSQ) was designed to provide a basis for general screening and comparison regardless of the disease. We here describe the final validation of its psychometric characteristics. Methods: The FSQ consists of a brief semi-structured interview and 44 dichotomic items, and has now been administered to 811 caregivers (285 were simultaneously administered other questionnaires assessing anxiety and depressive symptoms). After a factorial analysis confirmed the 5-factor structure identified in previous studies (emotional burden, problems in social involvement, need for knowledge about the disease, satisfaction with family relationships, and thoughts about death), we undertook correlation and reliability analyses, and a receiver operating characteristics curve analysis designed to determine the cut-off point for the emotional problems identified by the first factor. Finally, univariate ANOVA with Bonferroni's post-hoc test was used to compare the disease-specific scores. Results: The validity and reliability of the FSQ is good, and its factorial structure refers to areas that are internationally considered as being of general importance. The semi-structured interview collects information concerning the socio-economic status of caregivers and their convictions/interpretations concerning the diseases of their patients. Conclusions: The FSQ can be used as a single instrument for the general assessment of caregiving-related problems regardless of the reference disease. This makes it possible to reduce administration and analysis times, and compare the problems experienced by the caregivers of patients with different diseases.
Assessing and improving removable partial denture learning outcome by using proficiency tests results.

Background: Feedback of the weak areas of knowledge in RPD using continuous competency or other test forms is very essential to develop the student knowledge and the syllabus as well. This act should be a regular practice. Aim: To use the outcome of competency test and the objectives structured clinical examination of removable partial denture as a reliable measure to provide a continuous feedback to the teaching system. Method: This sectional study was performed on sixty eight, fifth year students for the period from 2009 to 2010. The experiment was divided into two parts: continuous assessment and the final examination. In the first essay; some basic removable partial denture knowledge, surveying technique, and designing of the metal framework were used to estimate the learning outcome. While in the second essay, some components of the objectives structured clinical examination were compared to the competency test to see the difference in learning outcome. Results: The students’ performance was improved in the final assessment just in some aspects of removable partial denture. However, for the surveying, the students faced some problems. Conclusion: the continuous and final tests can provide a simple tool to advice the teachers for more effective teaching of the RPD. So that the weakness in specific aspects of the RPD syllabus can be detected and corrected continuously from the beginning, during and at the end of the course.