LLukas22/scidocs huggingface dataset:
Automated Vehicle Parking System using RFID

Radio Frequency Identification (RFID) technology is very useful technology in automation of vehicle parking system in mall/building. One of the challenging problems for many vehicle owners in big cities is where to park their vehicles. If the parking slot is known in advance one can save precious time and fuel wastage. In our proposed system the user is informed about the parking slot availability at a particular parking location .The slot availability details are collected using an RFID system and are updated periodically into the database [1]. Entry-point and exit-point of the parking-lots will be under control with RFID readers, labels and barriers. Personnel costs will be reduced considerably using this technology. Entry-point and exit-point will be handled in a fast manner without having to stop the cars so that traffic jam problem will be avoided during these processes. Drivers will not have to stop at the circulation points and parking tickets will be out of usage during Entry-point and exit-point. Because we have added recharge module therefore user has to register into the system and he will get message of balance on his mobile. It will be avoided ticket-jamming problems for the ticket processing machines as well. Vehicle owners will not have to make any payments at each Entry-point thus a faster traffic flow will be possible. Since there won't be any waiting during Entry-point and exit-points the pollution problem will be avoided. Automated parking system certainly reduce the total cost of RFID parking system infrastructure without re-modifying the existed hardware. It also gives functioning for video surveillance which will captures objects which are in front of camera [2].
Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis in children and adolescents.

OBJECTIVE
To report the clinical features of anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis in patients < or = 18 years old.


METHODS
Information was obtained by the authors or referring physicians. Antibodies were determined by immunocytochemistry and enzyme-linked immunosorbent assay (ELISA) using HEK293 cells ectopically expressing NR1.


RESULTS
Over an 8-month period, 81 patients (12 male) with anti-NMDAR encephalitis were identified. Thirty-two (40%) were < or =18 years old (youngest 23 months, median 14 years); 6 were male. The frequency of ovarian teratomas was 56% in women >18 years old, 31% in girls < or =18 years old (p = 0.05), and 9% in girls < or =14 years old (p = 0.008). None of the male patients had tumors. Of 32 patients < or =18 years old, 87.5% presented with behavioral or personality change, sometimes associated with seizures and frequent sleep dysfunction; 9.5% with dyskinesias or dystonia; and 3% with speech reduction. On admission, 53% had severe speech deficits. Eventually, 77% developed seizures, 84% stereotyped movements, 86% autonomic instability, and 23% hypoventilation. Responses to immunotherapy were slow and variable. Overall, 74% had full or substantial recovery after immunotherapy or tumor removal. Neurological relapses occurred in 25%. At the last follow-up, full recovery occurred more frequently in patients who had a teratoma that was removed (5/8) than in those without a teratoma (4/23; p = 0.03).


INTERPRETATION
Anti-NMDAR encephalitis is increasingly recognized in children, comprising 40% of all cases. Younger patients are less likely to have tumors. Behavioral and speech problems, seizures, and abnormal movements are common early symptoms. The phenotype resembles that of the adults, although dysautonomia and hypoventilation are less frequent or severe in children. Ann Neurol 2009;66:11-18.
Risk, reward, and economic decision making in aging.

OBJECTIVES
Older adults' decision quality is considered to be worse than that of younger adults. This age-related difference is often attributed to reductions in risk tolerance. Little is known about the circumstances that affect older adults' decisions and whether risk attitudes directly influence economic decisions. We measure the influence of risk attitudes on age-related differences in decision making in both nonsocial and social contexts.


METHODS
Risk attitudes and economic decision making were measured in 30 healthy older adults and 29 healthy younger adults.


RESULTS
Older adults report being less impulsive, sensation seeking and risk tolerant than younger adults. Age did not affect a measure of nonsocial economic decision making. Older adults were more likely to reject unfair divisions of money during an economic social-bargaining game and more likely to make equitable divisions of money during social-giving game. These age-related differences were determined in part by individuals' self-reported risk taking.


DISCUSSION
We conclude that age-related differences in decision making are domain specific and that some social economic decision making is influenced by risk attitudes. Older adults are more risk avoidant, but this does not alter their willingness to wait for reward in a nonsocial context. Perceiving more risk is associated with an unwillingness to accept an unfair offer in social economic contexts and ultimately leads to poorer outcomes for older adults.
Effects of ibuprofen on molecular markers of cartilage and synovium turnover in patients with knee osteoarthritis.

OBJECTIVE
The aim of this study was to evaluate the effect of ibuprofen on the urinary excretion of C-terminal crosslinking telopeptide of type II collagen (CTX-II) and urinary glucosyl galactosyl pyridinoline (Glc-Gal-PYD), two new molecular markers of cartilage and synovial tissue metabolism, respectively, in patients with knee osteoarthritis (OA).


METHODS
We studied 201 patients with knee pain and radiographic evidence of knee OA who were on treatment with non-steroidal anti-inflammatory drugs (NSAIDs) prior to study initiation. After an initial screening visit, patients were withdrawn from their pre-study NSAID and, following a flare of their OA symptoms, were randomised to ibuprofen (2400 mg/day) or placebo. Urinary CTX-II and Glc-Gal-PYD levels were measured at time of randomisation (baseline) and after 4-6 weeks of treatment.


RESULTS
After 4 to 6 weeks, urinary CTX-II (+17%, p = 0.023) and Glc-Gal-PYD (+10%, p = 0.020) increased significantly from baseline in the placebo group whereas marginal or no increase was observed in the ibuprofen group (CTX-II +2%, NS and Glc-Gal-PYD +4%, p = 0.045). For urinary CTX-II, the difference in the change from baseline between placebo and ibuprofen treated groups was significant (13%, p = 0.017). At baseline, urinary levels of CTX-II and Glc-Gal-PYD were higher in patients with knee swelling (n = 127) than in those without (n = 74) (p<0.02 for both markers). When patients were stratified according to presence or absence of knee swelling at baseline, the increases over 4-6 weeks of urinary CTX-II and Glc-Gal-PYD in the placebo group were restricted to patients with knee swelling (+22% from baseline, p = 0.001 and +12%, p = 0.011, for urinary CTX-II and Glc-Gal-PYD respectively). In patients with knee swelling who were treated with ibuprofen this increase was not observed and the difference from placebo was significant for urinary CTX-II (p = 0.014).


CONCLUSION
In patients with a flare of knee OA, specifically in patients with evidence of joint inflammation documented by knee swelling, there was a significant increase in markers reflecting cartilage and synovium metabolism that could partly be prevented by high doses of ibuprofen. These data suggest that patients with a flare of knee OA are characterised by increased cartilage and synovial tissue degradation, which may be partly prevented by high doses of NSAIDs.
An introduction to exponential random graph (p*) models for social networks

This article provides an introductory summary to the formulation and application of exponential random graph models for social networks. The possible ties among nodes of a network are regarded as random variables, and assumptions about dependencies among these random tie variables determine the general form of the exponential random graph model for the network. Examples of different dependence assumptions and their associated models are given, including Bernoulli, dyad-independent and Markov random graph models. The incorporation of actor attributes in social selection models is also reviewed. Newer, more complex dependence assumptions are briefly outlined. Estimation procedures are discussed, including new methods for Monte Carlo maximum likelihood estimation. We foreshadow the discussion taken up in other papers in this special edition: that the homogeneous Markov random graph models of Frank and Strauss [Frank, O., Strauss, D., 1986. Markov graphs. Journal of the American Statistical Association 81, 832–842] are not appropriate for many observed networks, whereas the new model specifications of Snijders et al. [Snijders, T.A.B., Pattison, P., Robins, G.L., Handock, M. New specifications for exponential random graph models. Sociological Methodology, in press] offer substantial improvement. © 2006 Elsevier B.V. All rights reserved.
Wire bonding with Pd-coated copper wire

The last three years have seen an aggressive implementation of fine-pitch copper wire bonding in face of ever-increasing gold prices. Numerous technical hurdles associated with copper wire bonding have mostly been overcome. However, achieving process robustness equivalent to gold wire bonding is still challenging and requires enhanced manufacturing control procedures. Although the 2nd bond in copper wire bonding is generally very reliable, it often requires additional process steps, such as skidding or scrubbing motions. These processes require additional time and cause an overall reduction in wire bonder throughput. Pd-coated Cu wire is emerging as an alternative to bonding with bare Cu wire. While not quite achieving the same cost savings as bare copper wire, it offers the promise of a more robust bonding process. Being a noble metal, the Pd-coating prevents oxidation of the wire surface. This improves 2nd bond performance, increases shelf life and protects the wire against corrosion. Better 2nd bond performance may allow for faster 2nd bond processes in some applications and hence greater throughput relative to bare copper. The effect of the Pd on the first bond is less certain. While residual Pd on the ball surface may enhance adhesion by analogy to the improvement seen at 2nd bond, the distribution of the Pd on the surface and within the ball is generally not uniform. Cross-sectional analysis of free air ball formed under different EFO parameters revealed different Pd distribution within the ball with more non-uniform mixing and swirling structures at high EFO current settings. In addition, formation of Pd-Cu alloys in the ball will increase its hardness at high EFO settings compared to low settings and may in turn exacerbate damage to bond pads, which is already a problem in copper wire bonding. This paper compares the bonding performance of Pd-coated Cu wire to bare copper wire at both 1st and 2nd bond. Bond strengths and process window are characterized. It is shown that Pd-coated wire can be successfully bonded using nitrogen rather than forming gas as the cover gas during ball formation. Bonding with nitrogen would partially recover the higher cost of the wire relative to bare Cu.
Effect of short-term synbiotic treatment on plasma p-cresol levels in patients with chronic renal failure: a randomized clinical trial.

BACKGROUND AND AIMS
In patients with chronic kidney disease (CKD), alterations in gut microbiome are posited to be responsible for gastrointestinal symptoms and generation of p-cresol, a uremic toxin that has been associated with CKD progression and cardiovascular mortality. This pilot study investigated whether Probinul-neutro®, a synbiotic that normalizes intestinal microflora, may lower plasma p-cresol concentrations and reduce gastrointestinal symptoms in non-dialyzed CKD patients.


METHODS AND RESULTS
This was a double-blind, randomized placebo-controlled trial. Thirty patients on 3-4 CKD stages were randomized to receive either Probinul neutro® or placebo for 4 weeks. Total plasma p-cresol concentration was assessed at baseline, and 15 and 30 days after treatment start. At the same study times, ease and frequency of defecation, upper and lower abdominal pain, stool shape, borborygmi, and flatus were quantified by subjective assessment questionnaires. Compared to baseline total plasma p-cresol median concentrations on 15th and 30th day were significantly lower in patients receiving Probinul-neutro® (2.31 and 0.78 vs. 3.05 μg/ml, p < 0.05; n = 18); no changes of plasma p-cresol concentrations were recorded in placebo-treated patients. No significant changes in gastrointestinal symptoms were observed during the study both in Probinul-neutro®-treated and placebo-treated patients.


CONCLUSION
Probinul-neutro® lowered total plasma p-cresol concentrations but did not ameliorate gastrointestinal symptoms in non-dialyzed CKD patients. Because high plasma concentrations of p-cresol in early phases of CKD are predictive of progression to end-stage renal disease, the results of our study suggest that synbiotics deserve attention as possible tools to delay CKD progression towards end-stage renal disease (ESRD).


CLINICALTRIALSGOV IDENTIFIER
NCT02008331.
Self-directed learning: views of teachers and students.

AIM
This paper reports the findings of an investigation into teachers' and students' understanding of the term self-directed learning (SDL), and their views concerning its value in paediatric intensive care (PIC) nurse education.


METHODS
Qualitative methods of data collection and analysis were used. The findings from interviews with teachers and students across eight PIC nursing courses are reported. Local Research Ethics Committee protocols were followed. Data were analysed using constant comparative analysis.


FINDINGS
Teachers and students appeared to experience some difficulty in articulating a precise definition of SDL. Both groups saw it as one teaching and learning method to be used alongside others, and focused their definitions on the observable events thought to demonstrate self-direction rather than the cognitive processes involved. Teachers and students considered SDL of some value, but only when used in conjunction with teacher-led methods. Both teachers and students felt that students take more responsibility for learning in SDL than in traditional teaching. However, there was a difference of opinion as to the manner in which responsibility was devolved and accepted, and neither party was completely convinced that the other respected them.


LIMITATIONS
The study explored only PIC nurse education, and was not intended to be generalized beyond this field.


CONCLUSION
The evidence from this study suggests that SDL has elusive qualities which defy precise definition. It appears that attempting such a definition and reducing SDL to an observable form may detract from its perceived value. It can be inferred from this study that in order to implement SDL issues of control and autonomy within the learning environment merit further exploration, rather than simply focusing on observable teaching and learning tools or methods.
Phellodendron and Citrus extracts benefit joint health in osteoarthritis patients: a pilot, double-blind, placebo-controlled study

BACKGROUND
The objective of this clinical study was to assess the potential benefit of a dietary supplement, NP 06-1, on joint health in overweight and normal weight adults diagnosed with osteoarthritis.


METHODS
An 8-week placebo-controlled, randomized, double-blind study was conducted with four groups comparing the effects of NP 06-1 to placebo on overweight and normal weight subjects diagnosed with primary osteoarthritis of the knee. NP 06-1 (a combination of two botanical extracts; Phellodendron amurense bark and Citrus sinensis peel) or matching placebo were given in a dose of two capsules (370 mg each) twice daily. The outcome measures were the Lequesne Algofunctional Index (LAI) for joint pain and movement as well as biomarkers of inflammation (C-reactive protein [CRP] and erythrocyte sedimentation rate [ESR]).


RESULTS
Eighty (80) subjects were enrolled and 45 subjects completed the study. No serious adverse events were reported. The mean total LAI scores at baseline for the four groups ranged from 11.4 to 12.4 (SD 1.2 to 2.4). Treatment for 8 weeks resulted in a statistical improvement in the LAI score in the overweight treatment group compared to placebo (6.3 +/- 2.3 vs 11.8 +/- 1.5; p < 0.0001). At 8 weeks, a similar result was observed in the normal weight groups (7.7 +/- 1.4 vs 9.9 +/- 0.9; p < 0.0001). There was a reduction in CRP levels with treatment in the overweight treatment group at 8 weeks (-0.62 +/- 0.2; 49%) compared to baseline (p < 0.001) and to placebo (p < 0.001). For the normal weight participants, there were significant reductions in CRP compared to baseline, but not to the matched placebo group. Both overweight and normal weight treatment groups lost a significant amount of weight compared to their placebo groups. The overweight treatment group lost an average of 5% body weight after 8 weeks. There was no significant change in ESR in any of the groups.


CONCLUSION
In this pilot study, NP 06-1 had beneficial effects on symptoms of osteoarthritis of the knee as measured using LAI scores and had anti-inflammatory effects as measured using CRP. Administration of NP 06-1 was also associated with weight loss, which may have been a contributing factor to the other benefits.
Sofosbuvir and Velpatasvir for HCV Genotype 1, 2, 4, 5, and 6 Infection.

BACKGROUND
A simple treatment regimen that is effective in a broad range of patients who are chronically infected with the hepatitis C virus (HCV) remains an unmet medical need.


METHODS
We conducted a phase 3, double-blind, placebo-controlled study involving untreated and previously treated patients with chronic HCV genotype 1, 2, 4, 5, or 6 infection, including those with compensated cirrhosis. Patients with HCV genotype 1, 2, 4, or 6 were randomly assigned in a 5:1 ratio to receive the nucleotide polymerase inhibitor sofosbuvir and the NS5A inhibitor velpatasvir in a once-daily, fixed-dose combination tablet or matching placebo for 12 weeks. Because of the low prevalence of genotype 5 in the study regions, patients with genotype 5 did not undergo randomization but were assigned to the sofosbuvir-velpatasvir group. The primary end point was a sustained virologic response at 12 weeks after the end of therapy.


RESULTS
Of the 624 patients who received treatment with sofosbuvir-velpatasvir, 34% had HCV genotype 1a, 19% genotype 1b, 17% genotype 2, 19% genotype 4, 6% genotype 5, and 7% genotype 6. A total of 8% of patients were black, 19% had cirrhosis, and 32% had been previously treated for HCV. The rate of sustained virologic response among patients receiving sofosbuvir-velpatasvir was 99% (95% confidence interval, 98 to >99). Two patients receiving sofosbuvir-velpatasvir, both with HCV genotype 1, had a virologic relapse. None of the 116 patients receiving placebo had a sustained virologic response. Serious adverse events were reported in 15 patients (2%) in the sofosbuvir-velpatasvir group and none in the placebo group.


CONCLUSIONS
Once-daily sofosbuvir-velpatasvir for 12 weeks provided high rates of sustained virologic response among both previously treated and untreated patients infected with HCV genotype 1, 2, 4, 5, or 6, including those with compensated cirrhosis. (Funded by Gilead Sciences; ClinicalTrials.gov number, NCT02201940.).
Twitter brand sentiment analysis: A hybrid system using n-gram analysis and dynamic artificial neural network

Twitter messages are increasingly used to determine consumer sentiment towards a brand. The existing literature on Twitter sentiment analysis uses various feature sets and methods, many of which are adapted from more traditional text classification problems. In this research, we introduce an approach to supervised feature reduction using n-grams and statistical analysis to develop a Twitter-specific lexicon for sentiment analysis. We augment this reduced Twitter-specific lexicon with brand-specific terms for brand-related tweets. We show that the reduced lexicon set, while significantly smaller (only 187 features), reduces modeling complexity, maintains a high degree of coverage over our Twitter corpus, and yields improved sentiment classification accuracy. To demonstrate the effectiveness of the devised Twitter-specific lexicon compared to a traditional sentiment lexicon, we develop comparable sentiment classification models using SVM. We show that the Twitter-specific lexicon is significantly more effective in terms of classification recall and accuracy metrics. We then develop sentiment classification models using the Twitter-specific lexicon and the DAN2 machine learning approach, which has demonstrated success in other text classification problems. We show that DAN2 produces more accurate sentiment classification results than SVM while using the same Twitter-specific lexicon. 2013 Elsevier Ltd. All rights reserved.
Successful myomectomy during pregnancy : A case report

BACKGROUND
The medical literature has reported an increase in myomectomy during caesarean section in the past decade. However, myomectomy performed during pregnancy remains a rarity. The management of uterine fibroids during pregnancy is usually expectant and surgical removal is generally delayed until after delivery. We present a case of a large, symptomatic uterine fibroid diagnosed during pregnancy which was successfully managed by antepartum myomectomy.


CASE PRESENTATION
A 30 year old woman presented with a one year history of abdominal swelling, amenorrhea and severe epigastric discomfort of 19 weeks duration. The abdomen was grossly distended and tense. A sonographic diagnosis of ovarian tumor in pregnancy was made. Laparotomy revealed a 32 cm degenerating subserosal uterine fibroid co-existing with an intrauterine pregnancy. Myomectomy was successfully performed. The subsequent antenatal period was uneventful with a spontaneous vaginal delivery of a female baby at 38 weeks.


CONCLUSION
This report supports other studies and case series that have demonstrated the safety of myomectomy during pregnancy in selected circumstances.
Cyberspace Forensics Readiness and Security Awareness Model

The goal of reaching a high level of security in wireless and wired communication networks is continuously proving difficult to achieve. The speed at which both keepers and violators of secure networks are evolving is relatively close. Nowadays, network infrastructures contain a large number of event logs captured by Firewalls and Domain Controllers (DCs). However, these logs are increasingly becoming an obstacle for network administrators in analyzing networks for malicious activities. Forensic investigators mission to detect malicious activities and reconstruct incident scenarios is extremely complex considering the number, as well as the quality of these event logs. This paper presents the building blocks for a model for automated network readiness and awareness. The idea for this model is to utilize the current network security outputs to construct forensically comprehensive evidence. The proposed model covers the three vital phases of the cybercrime management chain, which are: 1) Forensics Readiness, 2) Active Forensics, and 3) Forensics Awareness. Keywords—Network Forensics; Forensics Readiness; Network Security; Active Forensics; Reactive Forensics; Forensics Awareness and Network Security model