LLukas22/scidocs huggingface dataset:
Pharmacist-led medication education in cancer pain control: a multicentre randomized controlled study in Guangzhou, China.

OBJECTIVE
To evaluate clinical pharmacist-led pain-medication education in patients with cancer.


METHODS
A controlled study was conducted prospectively at six tertiary hospitals in China. In-patients with cancer were randomized to receive conventional treatment plus medication education or no education (controls). Education consisted of access to information booklets and eight 30-min face-to-face counselling sessions given by clinical pharmacists over 4 weeks. Patients completed pain- and analgesic-knowledge assessments and a Brief Pain Inventory, pre- and post-study.


RESULTS
A total of 123 and 114 patients in the education and control groups, respectively, completed follow-up. At the end of the study, patient knowledge regarding cancer pain and pain control was significantly increased in both groups; pain and analgesic knowledge scores were significantly higher in the education group compared with controls. In the control group, the increase in total pain-related knowledge was significantly greater in analgesic-naïve patients compared with those who were using/had used analgesics. Pain intensity scores and pain interference of daily activities were significantly reduced in the education group compared with controls.


CONCLUSIONS
Clinical pharmacist-led medication education resulted in improved pain control in patients with cancer.
Structured Synchronous Implementation of an Enhanced Recovery Program in Elective Colonic Surgery in 33 Hospitals in The Netherlands

It has been clearly shown that after elective colorectal surgery patients benefit from multimodal perioperative care programs. The Dutch Institute for Health Care Improvement started a breakthrough project to implement a multimodal perioperative care program of enhanced recovery after surgery (ERAS). This pre/post noncontrolled study evaluated the success of large-scale implementation of the ERAS program for elective colonic surgery using the breakthrough series. A total of 33 hospitals participated in this breakthrough project during 2005–2009. Each hospital performed a retrospective chart review to gather information on traditionally treated patients (pre-ERAS group, n = 1,451). During the subsequent year patients were treated according to the ERAS program (ERAS group, n = 1 034). Outcomes were length of stay (LOS), functional recovery, adherence to the protocol, and determinants of reduced LOS. Median LOS decreased significantly from 9 to 6 days (p < 0.001). In the ERAS group, functional recovery was reached within 3 days. Adherence to the protocol elements was high during the preoperative and perioperative phases but slightly lower during the postoperative phase. Younger age, female sex, American Society of Anesthesiologists grades I/II, and laparoscopic surgery were associated with decreased LOS. Care elements that positively influenced LOS were cessation of intravenous fluids and mobilization on postoperative day 1 and administration of laxatives postoperatively. The ERAS program was successfully implemented in one-third of all Dutch hospitals using the breakthrough series. Participating hospitals reduced the LOS by a median 3 days and were able to improve their standard of care in elective colonic surgery.
“Nomophobia”: Impact of Cell Phone Use Interfering with Symptoms and Emotions of Individuals with Panic Disorder Compared with a Control Group 

UNLABELLED
Panic disorder refers to the frequent and recurring acute attacks of anxiety.


OBJECTIVE
This study describes the routine use of mobiles phones (MPs) and investigates the appearance of possible emotional alterations or symptoms related to their use in patients with panic disorder (PD).


BACKGROUND
We compared patients with PD and agoraphobia being treated at the Panic and Respiration Laboratory of The Institute of Psychiatry, Federal University of Rio de Janeiro, Brazil, to a control group of healthy volunteers.


METHODS
An MP-use questionnaire was administered to a consecutive sample of 50 patients and 70 controls.


RESULTS
People with PD showed significant increases in anxiety, tachycardia, respiratory alterations, trembling, perspiration, panic, fear and depression related to the lack of an MP compared to the control group.


CONCLUSIONS
Both groups exhibited dependence on and were comforted by having an MP; however, people with PD and agoraphobia showed significantly more emotional alterations as well as intense physical and psychological symptoms when they were apart from or unable to use an MP compared to healthy volunteers.
Text Mining of News Articles for Stock Price Predictions

1 Problem Description This work is focused on the relationship between the news articles (breaking news) and stock prices. The student will design and develop methods to analyze how and when the news articles influence the stock market. News articles about Norwegian oil related companies and stock prices from " BW Offshore Limited " (BWO), " DNO International " (DNO), " Frontline " (FRO), " Petroleum Geo-Services " (PGS), " Seadrill " (SDRL), " Sevan Marine " (SEVAN), " Siem Offshore " (SIOFF), " Statoil " (STL) and " TGS-NOPEC Geophysical Company " (TGS) will be crawled, preprocessed and the important features in the text will be extracted to effectively represent the news in a form that allows the application of computational techniques. This data will then be used to train text sense classifiers. A prototype system that employs such classifiers will be developed to support the trader in taking sell/buy decisions. Methods will be developed for automaticall sense-labeling of news that are informed by the correlation between the changes in the stock prices and the breaking news. Performance of the prototype decision support system will be compared with a chosen baseline method for trade-related decision making. Abstract This thesis investigates the prediction of possible stock price changes immediately after news article publications. This is done by automatic analysis of these news articles. Some background information about financial trading theory and text mining is given in addition to an overview of earlier related research in the field of automatic news article analyzes with the purpose of predicting future stock prices. In this thesis a system is designed and implemented to predict stock price trends for the time immediately after the publication of news articles. This system consists mainly of four components. The first component gathers news articles and stock prices automatically from internet. The second component prepares the news articles by sending them to some document preprocessing steps and finding relevant features before they are sent to a document representation process. The third component categorizes the news articles into predefined categories, and finally the fourth component applies appropriate trading strategies depending on the category of the news article. This system requires a labeled data set to train the categorization component. This data set is labeled automatically on the basis of the price trends directly after the news article publication. An additional label refining step using clustering is added in an …
A noise-immune stylus analog front-end using adjustable frequency modulation and linear-interpolating data reconstruction for both electrically coupled resonance and active styluses

As the demand for intuitive and interactive displays is increasing in mobile devices such as smartphones and tablets, a pressure-sensitive stylus pen solution is needed for advanced user experiences [1-5]. Figure 10.4.1 compares electromagnetic resonance (EMR), active, and electrically coupled resonance (ECR) stylus systems, and shows cross-sectional views of sensor panels. EMR stylus systems have been successfully commercialized for high-end devices due to their battery-less, light, and pressure-sensing features [1-2]. However, EMR stylus systems require an extra sensing panel for electro-magnetic coupling. The active stylus system does not require the additional sensing panel but needs a battery located inside the stylus. On the other hand, ECR stylus systems are cost-effective without needing either the additional sensing panel or a built-in battery. Furthermore, ECR stylus systems measure pen pressure by sensing a stylus' resonant frequency change upon pressure without additional circuitry [3]. Due to the external noise injection to the stylus system being more than ten times larger than the pen signal as shown in Fig. 10.4.1, noise immunity is a key performance factor for commercialization. This paper proposes an analog front-end (AFE) for both ECR and active stylus systems with high noise immunity that results in improved signal-to-noise ratio (SNR) by applying a fully differential architecture, adjustable frequency modulation (AFM), and linear-interpolating data reconstruction (LIDR).
A Multi-Agent Service Framework for Context-Aware Elder Care

Advances in healthcare have led to longer life expectancy and the socalled aging population trend. The cost of caring for the elderly is rising progressively and threatens the economic well-being of many nations around the world. Instead of professional nursing facilities, many elderly people prefer living in their own homes independently. To enable successful aging in place, this research explores the roles of technology in improving the quality of life while reducing the cost of healthcare to the elder population. In particular, we propose a multi-agent service framework, called Context-Aware Service Integration System (CASIS), to integrate event-driven services with the OSGi service platform. This paper presents several context-aware service scenarios that have been developed on the proposed framework to demonstrate how context technologies and mobile web services can help enhance the quality of care for an elder’s daily life.
Results of m-polar Fuzzy Graphs with Application

An m-polar fuzzy model is useful for multi-polar information, multi-agent, multi-attribute and multiobject network models which gives more precision, flexibility, and comparability to the system as compared to the classical, fuzzy and bipolar fuzzy models. In this paper, m-polar fuzzy sets are used to introduce the notion of m-polar psi-morphism on product m-polar fuzzy graph (mFG). The action of this morphism is studied and established some results on weak and co-weak isomorphism. d2-degree and total d2-degree of a vertex in product mFG are defined and studied their properties. A real life situation has been modeled as an application of product mFG. c ©2018 World Academic Press, UK. All rights reserved.
Motion boundary based sampling and 3D co-occurrence descriptors for action recognition

Recent studies witness the success of Bag-of-Features (BoF) frameworks for video based human action recognition. The detection and description of local interest regions are two fundamental problems in BoF framework. In this paper, we propose a motion boundary based sampling strategy and spatialtemporal (3D) co-occurrence descriptors for action video representation and recognition. Our sampling strategy is partly inspired by the recent success of dense trajectory (DT) based features [1] for action recognition. Compared with DT, we densely sample spatial-temporal cuboids along motion boundary which can greatly reduce the number of valid trajectories while preserve the discriminative power. Moreover, we develop a set of 3D co-occurrence descriptors which take account of the spatial-temporal context within local cuboids and deliver rich information for recognition. Furthermore, we decompose each 3D co-occurrence descriptor at pixel level and bin level and integrate the decomposed components with a multi-channel framework, which can improve the performance significantly. To evaluate the proposed methods, we conduct extensive experiments on three benchmarks including KTH, YouTube and HMDB51. The results show that our sampling strategy significantly reduces the computational cost of point tracking without degrading performance. Meanwhile, we achieve superior performance than the state-ofthe-art methods. We report 95.6% on KTH, 87.6% on YouTube and 51.8% on HMDB51.
Migraine frequency and health utilities: findings from a multisite survey.

OBJECTIVES
Assess the relationship between migraine frequency and health utility.


METHODS
Patients aged >/=18 years diagnosed with episodic migraine were enrolled at three US sites representing varied models of health-care delivery. All subjects completed a questionnaire that included demographic and clinical information, a migraine-specific disability questionnaire, and the Health Utilities Index Mark 3 (HUI3). The HUI3 is a generic health status and health-related quality-of-life measure. HUI3 health status data are translated into utility scores anchored by 0 (dead) and 1 (perfect health).


RESULTS
The study enrolled 150 patients. The mean age was 44 years and 87% were female. Mean (+/-SD) monthly migraine frequency was 4.4 +/- 3.6, with 34% reporting </=2 migraines per month and 20% reporting >6 migraines per month. The mean (+/-SD) HUI3 score was 0.62 +/- 0.26. After controlling for study center, demographics, comorbidities, migraine characteristics, and level of migraine disruptiveness, migraine frequency was found to be significantly (P < 0.05) and negatively associated with HUI3 scores. Subjects with >6 migraines per month had an adjusted mean HUI3 score of 0.41; the corresponding mean for those reporting </=2 migraines per month was 0.67. Migraine frequency was positively associated with higher levels of disability for the emotion, cognition, and pain components of the HUI3.


CONCLUSIONS
Among this group of care-seeking patients, migraineurs' health utilities were inversely related to headache frequency. Although these data may not be generalizable to the entire migraine population, they may be useful in assessing the comparative cost-effectiveness of preventive migraine therapies.
Should we stop saying “epileptic”? A comparison of the effect of the terms “epileptic” and “person with epilepsy”

OBJECTIVE
The advantages and disadvantages of using "epileptic" as a noun to describe someone with epilepsy have long been debated. Recent high-profile recommendations have stated that the term should not be used, including in English, as it perpetuates stigma. This decision was largely informed by a Brazilian Global Campaign Against Epilepsy study that reported experimental evidence indicating that, with students, the label evokes more negative attitudes than "person with epilepsy". The generalizability of this effect to different countries/cultures, and thus the justification for the recommendations, has never been tested.


METHODS
We replicated the Brazilian study in the UK, in English, while also addressing methodological limitations. It was powered to detect the effects reported by the Brazilian study, with 234 students completing a survey regarding epilepsy attitudes. Half were randomized to Group 1 and half to Group 2. In Group 1, patients were referred to as "people/person with epilepsy" within the attitudinal measures, while in Group 2 they were referred to as "epileptic/s". Measures included translations of the questions used in the Brazilian study and the Attitudes and Beliefs about Living with Epilepsy scale. Participants' epilepsy familiarity and knowledge were also assessed.


RESULTS
The two groups were comparable in characteristics. A comparison of their responses to the attitude measures revealed no statistically significant or meaningful differences.


CONCLUSIONS
In this English replication, the word "epileptic" did not provoke more negative attitudes. This suggests that the effect reported by the Brazilian study might be culturally dependent. Methodological limitations to that study might also be relevant. Our results have implications for the global debate about how negative attitudes towards epilepsy might be addressed. Simply not saying "epileptic" may not promote the positive attitudes towards epilepsy that had been expected. To know how to best refer to those with epilepsy, evidence on the preferences of those actually living with epilepsy is needed.
Minimally invasive surgical ablation of atrial fibrillation: six-month results.

BACKGROUND
A minimally invasive surgery for treatment of atrial fibrillation was developed with bilateral pulmonary vein isolation, mapping, and ablation of the ganglionic plexi and excision of the left atrial appendage. A prospective multicenter registry was created to evaluate the outcomes.


METHODS
The procedure was performed through bilateral minithoracotomies with video assistance. It included bilateral pulmonary vein isolation with bipolar radiofrequency with documentation of conduction block, location of ganglionic plexi by high-frequency stimulation, and appropriate ablation and left atrial appendage exclusion/excision. Clinical follow-up at 6 months included monitoring with electrocardiogram, Holter, event monitor, or pacemaker interrogation.


RESULTS
One hundred fourteen patients with 60 (52.6%) paroxysmal, 32 (28.1%) persistent, and 22 (19.3%) long-standing persistent atrial fibrillations were treated. The mean age was 59.5 +/- 10.6 years, and 69.3% were men. The mean follow-up period was 204 +/- 41 days (median 195). There were 2 (1.8%) operative mortalities. At 6-month follow-up, with long-term monitoring, 52/60 (86.7%) patients with paroxysmal fibrillations were in normal sinus rhythm and 43/60 (71.7%) were both in normal sinus rhythm and off antiarrhythmic drugs. The patients with persistent atrial fibrillation had a lower success rate, with 18/32 (56.3%) being in normal sinus rhythm and 46.9% both in normal sinus rhythm and off antiarrhythmic drugs; for long-standing persistent cases, 11/22 (50%) were in normal sinus rhythm and 7/22 (31.9%) were also off antiarrhythmic drugs.


CONCLUSIONS
Minimally invasive atrial fibrillation surgery is an effective treatment of paroxysmal atrial fibrillation at 6 months. Continuous event monitoring is necessary to accurately assess treatment results. A more extensive lesion set seems to be required for treatment of persistent atrial fibrillation.
Arctic Societies, Cultures, and Peoples in a Changing Cryosphere

Changes in sea ice, snow cover, lake and river ice, and permafrost will affect economy, infrastructure, health, and indigenous and non-indigenous livelihoods, culture, and identity. Local residents are resilient and highly adaptive, but the rate and magnitude of change challenges the current adaptive capacity. Cryospheric changes create both challenges and opportunities, and occur along local, regional, and international dimensions. Such changes will provide better access to the Arctic and its resources thereby increasing human activities such as shipping and tourism. Cryospheric changes pose a number of challenges for international governance, human rights, safety, and search and rescue efforts. In addition to the direct effects of a changing cryosphere, human society is affected by indirect factors, including industrial developments, globalization, and societal changes, which contribute to shaping vulnerability and adaptation options. Combined with non-cryospheric drivers of change, this will result in multifaceted and cascading effects within and beyond the Arctic.
Effect of mivazerol on perioperative cardiac complications during non-cardiac surgery in patients with coronary heart disease: the European Mivazerol Trial (EMIT).

BACKGROUND
Mivazerol is a drug with alpha2-agonist properties that reduces post-ganglionic noradrenaline availability and spinal efferent sympathetic output.


METHODS
A double-blind randomized placebo-controlled trial was conducted in 61 European centers during a 2.5-yr period on 2,854 patients: 1,897 with coronary heart disease and 957 patients without overt coronary heart disease but classified as at high risk for it. The present analysis was restricted to those patients with previous known coronary heart disease of whom 48% had vascular surgery, 32% non-vascular thoracic or abdominal surgery, and 20% orthopedic surgery. Mivazerol or placebo were given intravenously from the induction of anesthesia for up to 72 h.


RESULTS
In the 1,897 patients with established coronary heart disease, mivazerol did not reduce the primary endpoint--the combination of myocardial infarction or death--or all-cause deaths significantly. A preplanned subgroup analysis of 904 patients with known coronary heart disease undergoing vascular surgery showed that there were fewer primary endpoints in those receiving mivazerol (risk ratio [RR], 0.67; 95% CL, 0.45-0.98; P = 0.037) and fewer cardiac deaths (6 of 454 vs. 18 of 450: RR, 0.33; 95% confidence limits, 0.13-0.82; P = 0.017). The all-cause death rate was also decreased (RR, 0.41; 95% CL, 0.18-0.91; P = 0.024), although there was no significant reduction in myocardial infarction.


CONCLUSION
The alpha2-adrenergic agonist, mivazerol, did not alter the rates of myocardial infarction or cardiac death in patients with known coronary heart disease undergoing noncardiac surgery. However, it may have protected patients undergoing vascular surgery from further coronary events, and a specific study of such patients is now indicated.
Vascular Plug-Assisted Retrograde Transvenous Obliteration for the Treatment of Gastric Varices and Hepatic Encephalopathy: A Prospective Multicenter Study.

PURPOSE
To evaluate technical and clinical outcomes of vascular plug-assisted retrograde transvenous obliteration (PARTO) for the treatment of gastric varices (GVs) and hepatic encephalopathy (HE).


MATERIALS AND METHODS
From March 2012 to June 2014, 73 consecutive patients (47 men, 26 women; mean age, 59 y; range, 28-79 y) who had undergone PARTO were evaluated in a prospective multicenter study. Among 57 patients with GVs, 28 had GVs in danger of rupture, 23 had experienced recent bleeding, and 6 had active variceal bleeding. The 16 patients with HE had been treated unsuccessfully with medical therapies.


RESULTS
Placement of the vascular plug and subsequent gelatin sponge embolization were technically successful in all 73 patients. There were no procedure-related complications. Follow-up CT obtained within 1 wk after PARTO showed complete thrombosis of GVs and portosystemic shunts in 72 of 73 patients (98.6%). Sixty patients who underwent follow-up longer than 3 mo showed complete obliteration of GVs and portosystemic shunts. There were no cases of variceal bleeding or HE at the end of follow-up (mean, 544 d). Improvement in Child-Pugh score was observed in 24 patients (40%) at 1-mo follow-up. Worsening of ascites and esophageal varices was observed in 14 (23.3%) and 16 (26.7%) patients at 3-mo follow-up.


CONCLUSIONS
The present results of PARTO indicate that it can be rapidly performed with high technical success and durable clinical efficacy for the treatment of GVs and HE in the presence of a portosystemic shunt. Therefore, PARTO might be considered a first-line treatment in appropriate patients.