LLukas22/scidocs huggingface dataset:
Open domain question answering using Wikipedia-based knowledge model

This paper describes the use of Wikipedia as a rich knowledge source for a question answering (QA) system. We suggest multiple answer matching modules based on different types of semi-structured knowledge sources of Wikipedia, including article content, infoboxes, article structure, category structure, and definitions. These semi-structured knowledge sources each have their unique strengths in finding answers for specific question types, such as infoboxes for factoid questions, category structure for list questions, and definitions for descriptive questions. The answers extracted from multiple modules are merged using an answer merging strategy that reflects the specialized nature of the answer matching modules. Through an experiment, our system showed promising results, with a precision of 87.1%, a recall of 52.7%, and an F-measure of 65.6%, all of which are much higher than the results of a simple text analysis based system. 2014 Elsevier Ltd. All rights reserved.
The cell biology of cell-in-cell structures

For decades, authors have described unusual cell structures, referred to as cell-in-cell structures, in which whole cells are found in the cytoplasm of other cells. One well-characterized process that results in the transient appearance of such structures is the engulfment of apoptotic cells by phagocytosis. However, many other types of cell-in-cell structure have been described that involve viable non-apoptotic cells. Some of these structures seem to form by the invasion of one cell into another, rather than by engulfment. The mechanisms of cell-in-cell formation and the possible physiological roles of these processes will be discussed.
Transient field distribution in gas-solid insulation systems under DC voltages

The development of electric fields in gas-solid insulation systems under dc voltage stress goes hand in hand with the accumulation and decay of charges on dielectric interfaces. The charge transport through the solid insulator and the gas is determined by the electric properties of the involved insulating materials. Therefore, the nonlinearly field-dependent volume conductivity of a gas, resulting from a constant charge generation rate by natural ionization has to be considered. The transient field distribution on insulators under dc voltage is investigated theoretically, using a gas model, which takes into account the physical characteristics of insulating gases like air and SF6 as well as the effects resulting from electron emission from the electrodes. The influence of the ion pair generation rate in the gas, the electric field strength, and the volume and surface conductivity of the solid insulating material on the development of the electric field is investigated on cylindrical and conical insulators which are typical for gas insulated systems. Results of calculations using the gas model are compared to simulations assuming constant gas conductivity. The simulation results are verified by measurements of the surface potential on cylindrical epoxy resin insulators in air.
Quantum fields as gravitational sources

The practice of setting quantum fields as sources for classical general relativity is examined. Several conceptual problems are identified which invalidate apparently innocuous equations. Alternative ways to links classical general relativity with quantum theory using Bohm's theory are proposed.
Effect of helicopter transport on neurological outcomes in a mouse model of embolic stroke with reperfusion: AIR-MICE pilot study.

BACKGROUND
Patients often suffer a stroke at a significant distance from a center capable of delivering endovascular therapy, thus requiring rapid transport by helicopter emergency medical services while receiving a recombinant tissue plasminogen activator infusion that was initiated locally. But little is known about how a helicopter flight may impact the safety and efficacy of recombinant tissue plasminogen activator-induced reperfusion and patient outcomes.


AIM
To establish a new animal method to address with fidelity the safety and overall effect of helicopter emergency medical services during thrombolysis.


METHODS
Prospective randomized open blinded end-point study of an actual helicopter flight exposure. Adult C57BL/6 male mice were treated with a 10 mg/kg recombinant tissue plasminogen activator infusion two-hours after an embolic middle cerebral artery occlusion. Mice were randomized in pairs to simultaneously receive the infusion during a local helicopter flight or in a ground hangar.


RESULTS
Eighteen mice (nine pairs) were analyzed. The paired t-test analysis showed nonsignificant smaller infarction volumes in the helicopter-assigned animals (mean pair difference 33 mm(3) , P = 0·33). The amount of hemorrhagic transformation between the helicopter and ground groups was 4·08 vs. 4·56 μl, respectively (paired t-test, P = 0·45).


CONCLUSIONS
This study shows that helicopter emergency medical services do not have an inherent adverse effect on outcome in a mouse model of ischemic stroke with reperfusion. These results endorse the safety of the practice of using helicopter emergency medical services in stroke patients. The observed potential synergistic effect of helicopter-induced factors, such as vibration and changes in altitude, with reperfusion merits further exploration in animal experimental models and in stroke patients.
Streptococcus anginosus group - cause of endocarditis and abscesses (S. milleri)

Classification, nomenclature and identification of the Streptococcus anginosus group (SAG) have been historically problematic and unreliable, mainly due to variability in bacteriological characteristics and clinical presentations. This group was first discovered in 1956 by Guthof, in reference to non-hemolytic streptococcal lassification, nomenclature and identification of the Streptococcus anginosus group (SAG) have been historically problematic and unreliable, mainly due to variability in bacteriological characteristics and clinical presentations.
Low doses of scopolamine increase cardiac vagal tone in the acute phase of myocardial infarction.

BACKGROUND
Reduced cardiac vagal tone in patients with myocardial infarction (MI) is associated with a high risk of sudden death. Muscarinic blocking agents in small doses induce a paradoxical increase in cardiac vagal activity in normal subjects. We tested whether low doses of scopolamine delivered transdermally enhance tonic and reflex cardiac vagal activity in patients in the acute phase of MI.


METHODS AND RESULTS
Patients were randomized to a scopolamine (n = 17) or a placebo patch (n = 19) in a double-blind fashion 4.20 +/- 0.18 days after acute MI. Cardiac vagal activity was assessed by testing the arterial baroreflex sensitivity (BRS) using the phenylephrine method and by power spectral analysis of the RR interval variability. Twenty-four hours after scopolamine, we found a significant increase in BRS (from 7.05 +/- 1.21 to 13.99 +/- 2.33 ms/mm Hg, P < .05) and in RR variability, expressed as the mean standard deviation of 512 normal consecutive RR intervals (from 18.09 +/- 2.64 to 31.16 +/- 4.16 milliseconds, P < .05). The amplitude of respiratory sinus arrhythmia, measured by the absolute power of the high-frequency spectral component, was also enhanced (from 62.55 +/- 21.49 to 305.33 +/- 95.68 milliseconds squared, P < .05), whereas the power in the low-frequency spectral component of the RR variability, which results from the interaction between cardiac sympathetic and vagal activity, did not change significantly (from 73.12 +/- 24.44 to 126.46 +/- 44.29 milliseconds squared, P = .93).


CONCLUSIONS
In patients in the acute phase of MI, low doses of scopolamine cause a sustained increase in cardiac vagal tone and improve the autonomic indices associated with mortality.
Evaluation of the Effectiveness of a Phone Based Care Coordination Pilot on Hospital Utilisation and Costs for Patients With Chest Pain.

BACKGROUND
A small percentage of the population represents a disproportionate number of attendances at emergency departments (ED). "Frequent presenters" to ED with chest pain do not always fit into established pathways for acute myocardial events. With accelerated "rule out" protocols, patients are often discharged from the ED after short lengths of stay. This research will evaluate the effectiveness of a phone based care-coordination pilot designed to meet the needs of patients attending ED with cardiac and non-cardiac chest pain.


METHODS
A longitudinal, single-arm interventional study with retrospectively recruited control group. Ninety-five patients were enrolled as the intervention group; 97 patients were retrospectively identified as controls. These patients had re-presented with chest pain within 6 months of a cardiac event, or attended hospital within 12 months two or more times with chest pain and/or complex needs. Intervention group patients were holistically assessed then phone-coached to support self-management of chest pain over 6 months. Following descriptive and univariate analysis, multivariate analysis was conducted to adjust for noted differences between the intervention and control groups.


RESULTS
Thirty-day representation to ED was significantly less for the intervention group (14.1%) compared to controls (27.7%). After adjusting for baseline differences, intervention patients were more than two-fold less likely to re-present compared to controls (OR=0.42, 95%CI: 0.19-0.96). After adjustment for baseline differences, the savings in subsequent inpatient costs was $1588 per person, as a result of intervention, patients were less likely to have inpatient readmissions (16.3%) compared to controls (20.2%), although this was not statistically significant (p=0.588).


CONCLUSION
A phone based care-coordination pilot with targeted interventions has the potential to reduce ED presentations and hospital readmissions among patients representing with chest pain.
Comparison of intraarterial and intravenous thrombolysis for ischemic stroke with hyperdense middle cerebral artery sign.

BACKGROUND AND PURPOSE
It is unclear whether intraarterial (IAT) or intravenous (IVT) thrombolysis is more effective for ischemic stroke with hyperdense middle cerebral artery sign (HMCAS) on computed tomography (CT). The aim of this study was to compare IAT and IVT in stroke patients with HMCAS.


METHODS
Comparison of data from 2 stroke units with similar management of stroke associated with HMCAS, except that 1 unit performed IAT with urokinase and the other IVT with plasminogen activator. Time to treatment was up to 6 hours for IAT and up to 3 hours for IVT. Outcome was measured by mortality and the modified Rankin Scale (mRS), dichotomized at 3 months into favorable (mRS 0 to 2) and unfavorable (mRS 3 to 6).


RESULTS
One hundred twelve patients exhibited a HMCAS, 55 of 268 patients treated with IAT and 57 of 249 patients who underwent IVT. Stroke severity at baseline and patient age were similar in both groups. Mean time to treatment was longer in the IAT group (244+/-63 minutes) than in the IVT group (156+/-21 minutes; P=0.0001). However, favorable outcome was more frequent after IAT (n=29, 53%) than after IVT (n=13, 23%; P=0.001), and mortality was lower after IAT (n=4, 7%) than after IVT (n=13, 23%; P=0.022). After multiple regression analysis IAT was associated with a more favorable outcome than IVT (P=0.003) but similar mortality (P=0.192).


CONCLUSIONS
In this observational study intraarterial thrombolysis was more beneficial than IVT in the specific group of stroke patients presenting with HMCAS on CT, even though IAT was started later. Our results indicate that a randomized trial comparing both thrombolytic treatments in patients with middle cerebral artery occlusion is warranted.
Clinical evaluation of De Marco formula as an adjunctive therapy for infected ischemic diabetic foot: a prospective randomized controlled trial.

BACKGROUND
De Marco Formula (DMF) is a novel formulation of procaine and PVP.


OBJECTIVE
To assess the efficacy and safety of DMF as an adjunctive therapy for infected ischemic diabetic foot in a prospective randomized controlled clinical trial.


METHODS
Adult patients, 39 male/ 79 female, were randomly assigned (59 patients/treatment group) to the conventional therapy alone (A) or plus DMF (0, 15 ml/kg .day i.m.) during ten days and them twice a week until healing of the lesions or completion of 52 days (B).The response to the treatment was considered favorable when an amputation was not needed even though a decrease of the wound area or complete healing was not shown. It was considered unfavorable when a major amputation was necessary because of worsening of the lesion (wound spreading to any magnitude greater than the initial one) or the appearance of new wounds in the same leg.


RESULTS
Both groups were comparable with regard to age, sex, level of arterial occlusion, type of lesion, anatomic localization of lesions and previous surgical procedures. The cumulative percentage of unfavorable results was significantly lower after treatment B with respect to treatment A (25.4% vs. 45.8%; p= 0.02), for a reduction of 44.5%. Four slight adverse reactions were associated with DMF: vertigo and nausea at the 7th treatment administration (one patient), and headache and tachycardia at the 12th dose (another patient). Blood hemoglobin and leukocyte counts and serum alanine transaminase were not affected.


CONCLUSION
The treatment with DMF for 52 days as an adjuvant for the conventional therapy was associated with a lower need for major amputations. It was also well tolerated and safe.
Canadian Quality Circle pilot project in osteoporosis: rationale, methods, and feasibility.

UNLABELLED
PROBLEM ADDRESSED Family physicians are not adequately following the 2002 Osteoporosis Canada guidelines for providing optimal care to patients with osteoporosis.


OBJECTIVE OF PROGRAM
The Canadian Quality Circle (CQC) pilot project was developed to assess the feasibility of the CQC project design and to gather information for implementing a national study of quality circles (QCs). The national study would assess whether use ofQCs could improve family physicians' adherence to the osteoporosis guidelines.


PROGRAM DESCRIPTION
The pilot project enrolled 52 family physicians and involved 7 QCs. The project had 3 phases: training and baseline data collection, educational intervention and follow-up data collection, and sessions on implementing strategies for care.


CONCLUSION
Findings from the pilot study showed that the CQC project was well designed and well received. Use of QCs appeared to be feasible for transferring knowledge and giving physicians an opportunity to analyze work-related problems and develop solutions to them.
From needs to goals and representations: Foundations for a unified theory of motivation, personality, and development.

Drawing on both classic and current approaches, I propose a theory that integrates motivation, personality, and development within one framework, using a common set of principles and mechanisms. The theory begins by specifying basic needs and by suggesting how, as people pursue need-fulfilling goals, they build mental representations of their experiences (beliefs, representations of emotions, and representations of action tendencies). I then show how these needs, goals, and representations can serve as the basis of both motivation and personality, and can help to integrate disparate views of personality. The article builds on this framework to provide a new perspective on development, particularly on the forces that propel development and the roles of nature and nurture. I argue throughout that the focus on representations provides an important entry point for change and growth. (PsycINFO Database Record
Bubbles and Total Factor Productivity

Evidence shows that asset price bubbles typically precede financial crises and financial crises are accompanied by the collapse of bubbles. In addition, stock market booms and busts are typically associated with credit market booms and busts. The recent US housing and stock markets bubbles and the subsequent Great Recession that began in late 2007 provide an example. The stock market booms in the early 1990s and the subsequent Asian financial crisis in 1997 provide another example. There are also many other related episodes of financial crisis in emerging economies. Motivated by these observations, Jianjun Miao and Pengfei Wang (2011a) propose a theory of credit-driven stock price bubbles. They show that a positive feedback loop mechanism generates stock price bubbles when firms borrow against the stock market value of their collateralized assets to finance investment. They assume that firms face stochastic investment opportunities and bubbles improve investment efficiency. They also study stochastic bubbles and policy implications.
Conference chair welcome message

On behalf of the University of Genoa, I would like to welcome you to IEEE SoSE2012, the Seventh International Conference on System of Systems Engineering in Genoa, Italy, technically sponsored by IEEE System, Man, and Cybernetics Society and by IEEE Reliability Society.
Feasibility of using automated insufflated carbon dioxide (CO2) for luminal distension in 3.0T MR colonography.

PURPOSE
Primary aim of our study was to prospectively evaluate the feasibility of automated carbon dioxide (CO(2)) delivery as luminal distending agent in 3.0T MR colonography.


MATERIALS AND METHODS
Rectally insufflated CO(2) was evaluated in four groups with different bowel preparation (A-D). Bowel preparation regimes were: gadolinium-based tagging (A), bowel purgation (B), barium-based tagging (C) and iodine-based tagging (D). Supine (3D)T1w-FFE and (2D)T2w-SSFSE series were acquired. Each colon was divided into six segments (cecum S1-rectum S6). Two observers independently assessed the presence of artefacts, diagnostic confidence and segmental colonic distension. Also characteristics of the residual stool (presence, composition and signal-intensity) were assessed per segment. Discomfort was assessed with questionnaires.


RESULTS
Fourteen healthy subjects were included. Colonic distension by means of rectally insufflated CO(2) was not associated with susceptibility artefacts. Overall image quality was affected by the presence of bowel motion-related artefacts: none of the segments in 3DT1w-series and 10/84 (12%) colon segments in 2DT2w-series were rated artefact-free by both observers. Diagnostic confidence ratings were superior for the 2DT2w-SSFSE series. Overall bowel distension was rated adequate to optimal in 312/336 (93%) colon segments.


CONCLUSION
MR colonography at 3.0T using carbon dioxide (CO(2)) for colonic distension is technically feasible. The presence of intraluminal CO(2) did not result in susceptibility artefacts, although overall image quality was influenced by artefacts.
Extract of Punica granatum inhibits skin photoaging induced by UVB irradiation.

BACKGROUND
Punica granatum (pomegranate) is kind of a fruit consumed fresh or in beverage. It has been widely used in traditional medicine in various parts of the world. In this study, we examined the efficacy of a Punica granatum (PG) extract in protecting skin against UVB-induced damage using cultured human skin fibroblasts.


METHODS
A Korean red PG sample was used, and its effects classified according to if the PG source originated from the rind, seed and fruit. The polyphenol content of PG, which is known to prevent other adverse cutaneous effects of UV irradiation, was measured by GC-MS. The protective effects of PG on UVB-induced skin photoaging were examined by determining the level of procollagen type I and MMP-1 after UVB irradiation.


RESULTS
Based on the GC-MS quantitative analysis, catechin, quercetin, kaempferol, and equol were the predominant compounds detected in PG. In the changes of expression of procollagen type I and MMP-1 in UV irradiated human skin fibroblasts treated PG, especially extract prepared from rind, the synthesis of collagen was increased and the expression of MMP-1 was decreased.


CONCLUSION
The major polyphenols in PG, particularly catechin, play a significant role in its photoprotective effects on UVB-induced skin damage.
Knowledge, attitude and practice of women in Campinas, São Paulo, Brazil with respect to physical exercise in pregnancy: a descriptive study

BACKGROUND
Pregnancy is a good time to develop healthy lifestyle habits including regular exercise and good nutrition. Programs of physical exercise for pregnant women have been recommended; however, there are few references on this subject in the literature. The objective of this study was to evaluate the knowledge, attitude and practice of pregnant women with respect to appropriate physical exercise during pregnancy, and also to investigate why some women do not exercise during pregnancy.


METHODS
A descriptive study was conducted in which 161 women of 18 to 45 years of age were interviewed in the third trimester of pregnancy. These women were receiving prenatal care at National Health Service (SUS) primary healthcare units and had no pathologies for which physical exercise would constitute a risk. The women were selected at an ultrasonography clinic accredited to the SUS in Campinas, São Paulo. A previously elaborated knowledge, attitude and practice (KAP) questionnaire was used to collect data, which were then stored in an Epinfo database. Statistical analysis was conducted using Pearson's chi-square test and Fisher's exact test to evaluate the association between the study variables (p < 0.05).


RESULTS
Almost two-thirds (65.6%) of the women were sufficiently informed about the practice of physical exercise during pregnancy and the vast majority (93.8%) was in favor of it. Nevertheless, only just over 20% of the women in this sample exercised adequately. Significant associations were found between an adequate knowledge of physical exercise during pregnancy and education level (p = 0.0014) and between the adequate practice of physical exercise during pregnancy and having had fewer pregnancies (p = 0.0001). Lack of time and feeling tired and uncomfortable were the principal reasons given by the women for not exercising.


CONCLUSION
These results suggest that women's knowledge concerning the practice of physical exercise during pregnancy is reasonable and their attitude is favorable; however, relatively few actually exercise during pregnancy.
Wear and mechanical properties of 6061-T6 aluminum alloy surface hybrid composites [(SiC+Gr) and (SiC+Al2O3)] fabricated by friction stir processing

In this investigation, the influence of tool rotational speed on wear and mechanical properties of aluminum alloy based surface hybrid composites fabricated via Friction stir processing (FSP) was studied. The fabricated surface hybrid composites have been examined by optical microscope for dispersion of reinforcement particles. Microstructures of all the surface hybrid composites revealed that the reinforcement particles (SiC, Gr and Al2O3) are uniformly dispersed in the nugget zone. It was observed that the microhardness decreases when increasing the rotational speed and showed higher microhardness value in Al–SiC/Al2O3 surface hybrid composite due to presence and pining effect of hard SiC and Al2O3 particles. It was also observed that high wear resistance exhibited in the Al–SiC/Gr surface hybrid composites due to presence of SiC and Gr acted as load bearing elements and solid lubricant respectively. The observed wear and mechanical properties have been correlated with microstructures and worn micrographs. © 2013 Brazilian Metallurgical, Materials and Mining Association. Published by Elsevier Editora Ltda.