LLukas22/scidocs huggingface dataset:
Adaptation to climate change in the developing world

The world’s climate is changing and will continue to change into the coming century at rates projected to be unprecedented in recent human history. The risks associated with these changes are real but highly uncertain. Societal vulnerability to the risks associated with climate change may exacerbate ongoing social and economic challenges, particularly for those parts of societies dependent on resources that are sensitive to changes in climate. Risks are apparent in agriculture, fisheries and many other components that constitute the livelihood of rural populations in developing countries. In this paper we explore the nature of risk and vulnerability in the context of climate change and review the evidence on present-day adaptation in developing countries and on coordinated international action on future adaptation. We argue that all societies are fundamentally adaptive and there are many situations in the past where societies have adapted to changes in climate and to similar risks. But some sectors are more sensitive and some groups in society more vulnerable to the risks posed by climate change than others. Yet all societies need to enhance their adaptive capacity to face both present and future climate change outside their experienced coping range. The challenges of climate change for development are in the present. Observed climate change, present-day climate variability and future expectations of change are changing the course of development strategies – development agencies and governments are now planning for this adaptation challenge. The primary challenge, therefore, posed at both the scale of local natural resource management and at the scale of international agreements and actions, is to promote adaptive capacity in the context of competing sustainable development objectives.
The ontogeny of gaze following in chimpanzees, Pan troglodytes, and rhesus macaques, Macaca mulatta

Primates follow the gaze direction of conspecifics to outside objects. We followed the ontogeny of this social-cognitive skill for two species: rhesus macaques and chimpanzees. In the first two experiments, using both a cross-sectional and a longitudinal design, we exposed individuals of different ages to a human looking in a specified direction. Rhesus infants first began reliably to follow the direction of this gaze at the end of the early infancy period, at about 5.5 months of age. Chimpanzees did not reliably follow human gaze until 3–4 years; this corresponds to the latter part of the late infancy period for this species. In the third experiment we exposed individuals of the same two species to a human repeatedly looking to the same location (with no special object at that location) to see if subjects would learn to ignore the looks. Only adults of the two species diminished their gaze-following behaviour over trials. This suggests that in the period between infancy and adulthood individuals of both species come to integrate their gaze-following skills with their more general social-cognitive knowledge about other animate beings and their behaviour, and so become able to deploy their gaze-following skills in a more flexible manner.
On Taxation in a Two-Sector Endogenous Growth Model with Endogenous Labor Supply

This paper examines the effects of taxation on long-run growth in a two-sector endogenous growth model with (i) physical capital as an input in the education sector and (ii) leisure as an additional argument in the utility function. The analysis of the effects of taxation including income taxation, capital income taxation and labor income taxation distinguishes between the case with a unique (interior) balanced growth path and the case with multiple balanced growth paths. Due to the flexibility of labor supply, taxation of income may induce agents to spend more or less time on leisure activities. In the case of income taxation, where capital and labor income are taxed equally, the resulting effect on the growth rate is negative. The contribution of endogenous leisure is confined to reducing or increasing the size of the effect on the growth rate. If only capital income is taxed, the direction of the effect may reverse. In that case, the positive effect of the increase in total non-leisure time dominates the direct negative effect, implying that capital taxation increases the long-run growth rate. JEL Classification: E20, H20, J22, J24, O41 ∗Address for correspondence: Paul de Hek, Department of Economics, H7-09, Erasmus University Rotterdam, P.O.Box 1738, 3000 DR Rotterdam, The Netherlands. Email: pdehek@few.eur.nl. Financial support from the Netherlands Organisation for Scientific Research (NWO) is gratefully acknowledged.
Emotional eating moderates the relationship of night eating with binge eating and body mass.

Night eating syndrome is marked by substantial evening or nocturnal food intake, insomnia, morning anorexia, and depressed mood. Night eating severity has been positively associated with body mass index (BMI), binge eating frequency, and emotional eating tendencies. We conducted an online questionnaire study among students (N=729) and explored possible interactive effects between those variables. Night eating severity, binge eating frequency, BMI and emotional eating were all positively correlated with each other. Regression analyses showed that night eating severity was particularly related to more frequent binge episodes and higher BMI at high levels of emotional eating but unrelated to those variables at low levels of emotional eating. Thus, eating as a means of emotion regulation appears to be an important moderator of the relationship between night eating and both binge eating and BMI.
JSgraph: Enabling Reconstruction of Web Attacks via Efficient Tracking of Live In-Browser JavaScript Executions

ing audit logs
On the Impact of Refactoring Operations on Code Quality Metrics

Refactorings are behavior-preserving source code transformations. While tool support exists for (semi) automatically identifying refactoring solutions, applying or not a recommended refactoring is usually up to the software developers, who have to assess the impact that the transformation will have on their system. Evaluating the pros (e.g., the bad smell removal) and cons (e.g., side effects of the change) of a refactoring is far from trivial. We present RIPE (Refactoring Impact Prediction), a technique that estimates the impact of refactoring operations on source code quality metrics. RIPE supports 12 refactoring operations and 11 metrics and it can be used together with any refactoring recommendation tool. RIPE was used to estimate the impact on 8,103 metric values, for 504 refactorings from 15 open source systems. 38% of the estimates are correct, whereas the median deviation of the estimates from the actual values is 5% (with a 31% average).
Elementary proofs of (relatively) recent characterizations of Eulerian graphs

Abstract Apart from the classical characterization of Eulerian graphs by Eulerian trails and cycle decompositions, there are other characterization theorems due to Toida and McKee, and to Shank respectively. However, while the proof of the Toida-McKee characterization theprem uses, partly, matroid theory, the proof of Shank's characterization theorem is based on considerations of binary vector spaces. In this paper, elementary graph theoretical proofs of these characterization theorems are presented.
Comparison of small area techniques for estimating prevalence of mental disorder symptoms among Iranian's southern adolescents.

BACKGROUND
Mental disorders may lead to several complications in adolescents' people whose compensation is very difficult and sometime impossible. They are prone to emotional problems. Therefore, knowing prevalence of diseases and valid statistical technique is necessary to plan for prevention and control of diseases.


METHODS
In this cross-sectional study; direct, synthetic, and post-stratified estimation as small area methods were used to compute mental disorder symptoms (MDS) prevalence with county-level reference among adolescents in south of Iran. We conducted Mental Health Study data (MHS) conducted in Bushehr Province, southern Iran in 2005 for individual-level classification of MDS (n=2584). Students were in grade 9, 10 and 11, and enrolled with complete satisfaction.


RESULTS
The synthetic method was superior to the direct and post-stratified technique with respect to discrepancy statistics such as MSE and width 95% confidence interval (MSEs(synthetic)≈0.001, MSEs(post-stratified)≈0.010, MSEs(direct)≈0.100). In addition, the width range of 95% confidence intervals for all county estimates was 9.7% to 65.3% based on in direct methods. Besides, the width range of 95% confidence intervals for all county estimates under post-stratified and synthetic method was 16.7% to 62.2% and 11.8 %-25.1%, respectively. Hence, we could categorize prevalence of mental disorder symptoms in Bushehr's counties into five categories based-on synthetic methods. Maximum and minimum prevalence belongs to Geneveh (0.403) and Dashty (0.398) counties, respectively.


CONCLUSIONS
The MHS cannot be used as a valid source of county-level mental health prevalence data and the small-area method such synthetic method should be used to estimate prevalence of mental disorder symptoms in county-level. Furthermore, the synthetic method improved MDS prevalence more than direct and post-stratified methods.
Using the WordNet Ontology in the GeoCLEF Geographical Information Retrieval Task

This paper describes how we managed to use the WordNet ontology for the GeoCLEF 2005 English monolingual task. Both a query expansion method, based on the expansion of geographical terms by means of WordNet synonyms and meronyms, and a method based on the expansion of
Pythium insidiosum keratitis in Israel.

PURPOSE
To report with morphologic and phylogenetic speciation the first case from Israel of Pythium insidiosum keratitis associated with contact-lens wear.


METHODS
Case report and literature review.


RESULTS
A 21-year-old man with a history of contact-lens use and water exposure was hospitalized in Israel for a corneal ulcer. The ulcer progressed despite intensive antibiotics. He flew home to the United States for further care. Examination revealed a corneal ulcer with hypopyon. The infection progressed despite intensive medical therapy, and a therapeutic penetrating keratoplasty was performed. Histology and cornea cultures from the host cornea revealed sparsely septate, branching hyphae, consistent with P. insidiosum. DNA sequencing of the Pythium isolate supported the clinical history that the infection was acquired outside of the United States. Despite intensive medical therapy and a second corneal transplant, the ulcer progressed, ultimately requiring enucleation.


CONCLUSION
This is the first reported case of culture-proven, contact lens-related Pythium keratitis originating from Israel. Pythium is a fungus-like, aquatic oomycete found in tropical climates. Human pythiosis is uncommon but associated with high morbidity. Case reports describe surgical cure of Pythium keratitis, but this case recurred despite two penetrating keratoplasties and maximal antifungal therapy. In cases of presumed fungal keratitis that do not respond to antifungals, the fungus should be sent for speciation because early surgical intervention is the only means to save the eye in ocular pythiosis.
Observations and considerations on a case of Mondor's syndrome associated with gigantomastia.

AIM
The study of the Mondor's syndrome as a possible complication of gigantomastia.


MATERIAL AND METHOD
A 49 year old woman, with gigantomastia, came to our observation for the presence of a large superficial vein of the left breast affected by thrombophlebitis, compatible with Mondor's syndrome.


RESULTS
A "Thorek" breast reduction was performed; the patient was discharged on the second postoperative day and the follow up was smooth and fee from any complications.


DISCUSSION
In the case we observed, gigantomastia had a clear role in the pathogenesis of the Mondor's disease; in fact, the excessive weight of the breasts caused stretching of the mammary dorsal vein evolving in phlebitis. In literature, among the causes related to Mondor's disease the pendulous breast is described, probably with the same dynamic we have seen in this patient, but has never reported, so obviously, the correlation between the two events. It's considered as good practice in the pre-operative evaluation, to make differential diagnosis with any cancer, that, in a certain percentage, is associated with Mondor's syndrome, and once established the causes of the pathology, it is imperative to eliminate them to prevent any relapses.


CONCLUSION
Among the various causes recognized as predisposing to Mondor's syndrome, there has never been described gigantomastia so far. The observation and treatment of a patient in whom the gigantomastia certainly led to the onset of Mondor's disease, has led us to consider this as one of the possible complications of gigantomastia, providing an additional cue to the treatment of this condition even at an early stage.
Gene Expression Patterns in the Outer Mantle Epithelial Cells Associated with Pearl Sac Formation

For pearl culture, nucleus and mantle grafts are implanted into the gonad of the host oyster. The epithelial cells of the implanted mantle graft elongate and surround the nucleus, and a pearl sac is formed. Shell matrix proteins secreted by the pearl sac play an important role in pearl formation. We studied the gene expression patterns of six shell matrix proteins (msi60, n16, nacrein, msi31, prismalin-14, and aspein) in the epithelial cells associated with pearl sac formation. There were differences in the expression patterns of the six genes in the epithelial cells, and the relative expression levels for msi60 and aspein differed between the mantle graft and pearl sac (48 days after implantation). Therefore, the gene expression patterns of the epithelial cells were genetically undetermined, and changed between before and after pearl sac formation. The gene expression patterns of the epithelial cells of the pearl sac may be regulated by the host oysters.
Reduced atherosclerotic burden in subjects with genetically determined low oxidative stress.

OBJECTIVE
NADPH oxidase, one of the most important enzymes producing reactive oxidant species, is suggested to play a role in experimental atherosclerosis, but its role in human atherosclerosis is still unclear. We hypothesized that a reduced activity of NADPH oxidase might be linked to a reduced atherosclerotic burden.


METHODS AND RESULTS
Thirty-one women carriers of hereditary deficiency of NOX2, the catalytic subunit of NADPH oxidase, were matched for sex and age with 31 controls and 31 obese women. Flow-mediated dilation and intima-media thickness, 2 surrogate markers of atherosclerosis, serum activity of NOX2, urinary isoprostanes, serum levels of nitrite/nitrate, and platelet production of isoprostanes and nitrite/nitrate were determined. Compared with controls (5.7±3.0% and 0.60±0.11 mm), carriers of NOX2 deficiency had higher flow-mediated dilation (9.2±5.0%; P<0.001) and lower intima-media thickness (0.50±0.11 mm; P=0.002), whereas obese women had lower flow-mediated dilation (3.2±2.1%; P=0.007) and higher intima-media thickness (0.71±0.15 mm; P<0.001). Compared with controls, carriers of NOX2 deficiency had lower urinary isoprostanes (132.6±87.3 versus 82.3±46.0 pg/mg creatinine; P=0.007) and serum NOX2 activity (24.9±19.3 versus 12.8±11.9 pg/mL; P=0.004) and higher serum nitrite/nitrate (23.8±7.6 versus 30.5±6.3 µmol/L; P<0.001), whereas obese women had higher urinary isoprostanes (132.6±87.3 versus 182.2±84.6 pg/mg creatinine; P=0.008) and serum NOX2 activity (24.9±19.3 versus 36.1±18.6 pg/mL; P=0.008) and lower serum nitrite/nitrate (23.8±7.6 versus 12.6±4.2 µmol/L; P<0.001). Flow-mediated dilation correlated with intima-media thickness (r=-0.433; P<0.001), serum NOX2 activity (r=-325; P<0.001), and urinary isoprostanes (r=-0.314; P=0.002). Ex vivo study showed that, compared with controls, platelets from carriers of NOX2 deficiency had lower isoprostanes (P<0.001) and higher nitrite/nitrate (P<0.001), whereas platelets from obese women had higher isoprostanes (P<0.001) and lower nitrite/nitrate (P=0.013).


CONCLUSIONS
The study shows reduced atherosclerotic burden in carriers of NOX2 deficiency, suggesting that oxidative stress generated by this enzymatic pathway is implicated in human atherosclerosis.
Quantity estimation in visualizations of tagged text

A valuable task in text visualization is to have viewers make judgments about text that has been annotated (either by hand or by some algorithm such as text clustering or entity extraction). In this work we look at the ability of viewers to make judgments about the relative quantities of tags in annotated text (specifically text tagged with one of a set of qualitatively distinct colors), and examine design choices that can improve performance at extracting statistical information from these texts. We find that viewers can efficiently and accurately estimate the proportions of tag levels over a range of situations; however accuracy can be improved through color choice and area adjustments.
Epratuzumab, a humanized anti-CD22 antibody, in aggressive non-Hodgkin's lymphoma: phase I/II clinical trial results.

PURPOSE
We conducted a single-center, dose-escalation study evaluating the safety, pharmacokinetics, and efficacy of epratuzumab, an anti-CD22 humanized monoclonal antibody, in patients with aggressive non-Hodgkin's lymphoma.


EXPERIMENTAL DESIGN
Epratuzumab was administered once weekly for 4 weeks at 120-1000-mg/m2 doses to 56 patients [most (n = 35) with diffuse large B-cell lymphoma].


RESULTS
Patients were heavily pretreated (median, 4 prior therapies), 25% received prior high-dose chemotherapy with stem cell transplant, and 84% had bulky disease (> or =5 cm). Epratuzumab was well tolerated, with no dose-limiting toxicity. Most (95%) infusions were completed within 1 h. The mean serum half-life was 23.9 days. Across all dose levels and histologies, objective responses (ORs) were observed in five patients (10%; 95% confidence interval, 3-21%), including three complete responses. In patients with diffuse large B-cell lymphoma, 15% had ORs. Overall, 11 (20%) patients experienced some tumor mass reduction. Median duration of OR was 26.3 weeks, and median time to progression for responders was 35 weeks. Two responses are ongoing at > or =34 months, including one rituximab-refractory patient.


CONCLUSIONS
These data demonstrate that epratuzumab has a good safety profile and exerts antitumor activity in aggressive non-Hodgkin's lymphoma at doses of > or =240 mg/m2, thus warranting further evaluation in this clinical setting.
Selective aberrant functional connectivity of resting state networks in social anxiety disorder

Several functional MRI (fMRI) activation studies have highlighted specific differences in brain response in social anxiety disorder (SAD) patients. Little is known, so far, about the changes in the functional architecture of resting state networks (RSNs) in SAD during resting state. We investigated statistical differences in RSNs on 20 SAD and 20 controls using independent component analysis. A diffuse impact on widely distributed RSNs and selective changes of RSN intrinsic functional connectivity were observed in SAD. Functional connectivity was decreased in the somato-motor (primary and motor cortices) and visual (primary visual cortex) networks, increased in a network including medial prefrontal cortex which is thought to be involved in self-referential processes, and increased or decreased in the default mode network (posterior cingulate cortex/precuneus, bilateral inferior parietal gyrus, angular gyrus, middle temporal gyrus, and superior and medial frontal gyrus) which has been suggested to be involved in episodic memory, and self-projection, the dorsal attention network (middle and superior occipital gyrus, inferior and superior parietal gyrus, and middle and superior frontal gyrus) which is thought to mediate goal-directed top-down processing, the core network (insula-cingulate cortices) which is associated with task control function, and the central-executive network (fronto-parietal cortices). A relationship between functional connectivity and disease severity was found in specific regions of RSNs, including medial and lateral prefrontal cortex, as well as parietal and occipital regions. Our results might supply a novel way to look into neuro-pathophysiological mechanisms in SAD patients.
Discovering work prioritisation patterns from event logs

Business process improvement initiatives typically employ various process analysis techniques, including evidence-based analysis techniques such as process mining, to identify new ways to streamline current business processes. While plenty of process mining techniques have been proposed to extract insights about the way in which activities within processes are conducted, techniques to understand resource behaviour are limited. At the same time, an understanding of resources behaviour is critical to enable intelligent and effective resource management an important factor which can significantly impact overall process performance. The presence of detailed records kept by today’s organisations, including data about who, how, what, and when various activities were carried out by resources, open up the possibility for real behaviours of resources to be studied. This paper proposes an approach to analyse one aspect of resource behaviour: the manner in which a resource prioritises his/her work. The proposed approach has been formalised, implemented, and evaluated using a number of synthetic and real datasets. © 2017 Elsevier B.V. All rights reserved.
A technique for orthogonal frequency division multiplexing frequency offset correction

HE TECHNIQUE described in this paper has been deT veloped to correct frequency offset errors in digital communications systems employing orthogonal frequency division multiplexing (OFDM) as the method of modulation. The aim of the paper is twofold; to show the effect offset errors have on the signal-to-noise ratio of the OFDM carriers and to present an algorithm to estimate offset so that it may be removed prior to demodulhhn. OFDM is a bandwidth efficient signalling scheme for digital communications that was first proposed by Chang [l]. The main difference bepeen frequency division multiplexing (FDM) and OFDM, is that in OFDM the spectrum of the individual carriers mutually overlap, giving therefore an optimun spectrum efficiency (asymptotically Q b/Hz for 2Q-ary modulation of each carrier). Nevertheless, the OFDM carriers exhibit orthogonality on a symbol interval if synthesized such that they are spaced in frequency exactly at the reciprocal of the symbol interval. Fortunately, this synthesis can be accomplished perfectly, in principle, utilizing the discrete Fourier ttansform (dft) as first described by Darlington [2] and later, for data modems, by Weinstein and Ebert [3]. With the recent evolution of integrated circuit digital signal processing (dsp) chips, OFDM has become practical to implement and