LLukas22/scidocs huggingface dataset:
Change in coronary blood flow after percutaneous coronary intervention in relation to baseline lesion physiology: results of the JUSTIFY-PCI study.

BACKGROUND
Percutaneous coronary intervention (PCI) aims to increase coronary blood flow by relieving epicardial obstruction. However, no study has objectively confirmed this and assessed changes in flow over different phases of the cardiac cycle. We quantified the change in resting and hyperemic flow velocity after PCI in stenoses defined physiologically by fractional flow reserve and other parameters.


METHODS AND RESULTS
Seventy-five stenoses (67 patients) underwent paired flow velocity assessment before and after PCI. Flow velocity was measured over the whole cardiac cycle and the wave-free period. Mean fractional flow reserve was 0.68±0.02. Pre-PCI, hyperemic flow velocity is diminished in stenoses classed as physiologically significant compared with those classed nonsignificant (P<0.001). In significant stenoses, flow velocity over the resting wave-free period and hyperemic flow velocity did not differ statistically. After PCI, resting flow velocity over the wave-free period increased little (5.6±1.6 cm/s) and significantly less than hyperemic flow velocity (21.2±3 cm/s; P<0.01). The greatest increase in hyperemic flow velocity was observed when treating stenoses below physiological cut points; treating stenoses with fractional flow reserve ≤0.80 gained Δ28.5±3.8 cm/s, whereas those fractional flow reserve >0.80 had a significantly smaller gain (Δ4.6±2.3 cm/s; P<0.001). The change in pressure-only physiological indices demonstrated a curvilinear relationship to the change in hyperemic flow velocity but was flat for resting flow velocity.


CONCLUSIONS
Pre-PCI physiology is strongly associated with post-PCI increase in hyperemic coronary flow velocity. Hyperemic flow velocity increases 6-fold more when stenoses classed as physiologically significant undergo PCI than when nonsignificant stenoses are treated. Resting flow velocity measured over the wave-free period changes at least 4-fold less than hyperemic flow velocity after PCI.
DDoS in the IoT: Mirai and Other Botnets

The Mirai botnet and its variants and imitators are a wake-up call to the industry to better secure Internet of Things devices or risk exposing the Internet infrastructure to increasingly disruptive distributed denial-of-service attacks.
HealthFace: A web-based remote monitoring interface for medical healthcare systems based on a wireless body area sensor network

The wireless body area sensor network (WBASN) is a type of wireless sensor network. The wireless sensor nodes in a WBASN are placed on, near, or within a human body. In a medical healthcare system, WBASNs continuously provide healthcare monitoring, especially of elderly or ill people, wherever the patient goes. Wireless nodes sense and process human vital signs such as heart rate, blood pressure, body temperature, and respiration. They then send collected data to a medical center via a base station in order for medical professionals to monitor the patient’s health. In the medical center, doctors and caregivers need monitoring systems or interfaces to process, analyze, and visualize the received data from WBASN-based systems. In this paper, we present a web-based remote monitoring interface, HealthFace, for medical healthcare systems based on a WBASN. Users can easily access the developed HealthFace via any Internet-connected device, such as a PC, PDA, laptop, or cell phone, without needing any special software or programs except for a web browser. In addition, the implemented HealthFace presents several features, including recording, displaying, and analyzing collected data from the sensor nodes using MATLAB Builder NE with Web Figure. Web Figure enables users to utilize 3-dimensional view, zoom, and movement functions.
The wetland continuum: A conceptual framework for interpreting biological studies

We describe a conceptual model, the wetland continuum, which allows wetland managers, scientists, and ecologists to consider simultaneously the influence of climate and hydrologic setting on wetland biological communities. Although multidimensional, the wetland continuum is most easily represented as a two-dimensional gradient, with ground water and atmospheric water constituting the horizontal and vertical axes, respectively. By locating the position of a wetland on both axes of the continuum, the potential biological expression of the wetland can be predicted at any point in time. The model provides a framework useful in the organization and interpretation of biological data from wetlands by incorporating the dynamic changes these systems undergo as a result of normal climatic variation rather than placing them into static categories common to many wetland classification systems. While we developed this model from the literature available for depressional wetlands in the prairie pothole region of North America, we believe the concept has application to wetlands in many other geographic locations.
Magnetic resonance guidance for radiofrequency ablation of liver tumors.

Image-guided thermal ablation of liver tumors is a minimally invasive treatment option. Techniques used for thermal ablation are radiofrequency (RF) ablation, laser interstitial thermotherapy (LITT), microwave (MW) ablation, high-intensity focused ultrasound (HIFU), and cryoablation. Among these techniques RF ablation attained widespread consideration. Image guidance should ensure a precise ablation therapy leading to a complete coagulation of tumor tissue without injury to critical structures. Therefore, the modality of image guidance has an important impact on the safety and efficacy of percutaneous RF ablation. The current literature regarding percutaneous RF ablation mainly describes the use of computed tomography (CT) and ultrasonography (US) guidance. In addition, interventional MR systems offer the possibility to utilize the advantages of MR imaging such as excellent soft-tissue contrast, multiplanar and interactive capabilities, and sensitivity to thermal effects during the entire RF ablation procedure. Monitoring of thermally induced coagulation by MR imaging is supportive to control the ablation procedure. MR imaging can be advantageously used to guide overlapping ablation if necessary as well as to define the endpoint of RF ablation after complete coverage of the target tissue is verified. Furthermore, monitoring of thermal effects is essential in order to prevent unintended thermal damage from critical structures surrounding the target region. Therefore, MR-guided RF ablation offers the possibility for a safe and effective therapy option in the treatment of primary and secondary hepatic malignancies. The article summarizes the role of MR guidance for RF ablation of liver tumors.
Quadrilateral mesh generation in polygonal regions

A method for generating quadrilateral finite element meshes in polygonal regions is presented. The method uses geometric algorithms and is based partially on a triangular mesh generator. After a 2-stage convex polygon decomposition of the polygonal region has been obtained and the quadrilateral size to be used in each convex polygon has been determined, a boundary-constrained quadrilateral mesh is constructed in each convex polygon starting from the interior of the polygon. Experimental results for quadrilateral meshes in three regions are provided.
Experimental measurements on resistive switching devices: Gaining hands-on experience

The maximum exploitation of the favorable properties and the analog nature of memristor technology in innovative applications can be guaranteed only by the deeper understanding of their behavior. Fully functional memristors are commercially available. However, lab experiments with memristors are a challenging step. In this direction, this paper presents some important considerations to carry out reliable measurements. Most importantly, the proposed experimental setup is composed of off-the-shelf components and an affordable data acquisition system, showing the way on how to bypass the need for expensive research equipment and expand memristor experimentation beyond research labs and into classrooms.
Drivers and barriers to the adoption of the digital television in portugal: the perspectives of the tv viewers and other main stakeholders

The main goal of the ADOPT-DTV project is to understand what are the most significant factors for the adoption of digital TV by the Portuguese population in the switchover context. On the 26th of April 2012, the analogue terrestrial television switchoff is planned to occur in Portugal, according to the schedule published by the national telecommunication regulator Anacom. Digital terrestrial TV was launched in the country in April 2009, turning Portugal into one of the countries with the most ambitious schedule - or risky, depending on the perspective - for the full transition from analogue to digital terrestrial television.
 We will start by presenting the objectives, theoretical framework and research design of the ADOPT-DTV project. Next, we will present the first results of the project focused on the barriers and drivers for the adoption of digital TV from two of the empirical studies which integrate it, namely, the quantitative inquiry applied to a representative sample of the Portuguese population and interviews with the main stakeholders in the digital TV area in Portugal. The perspectives of the television viewers are compared with other main stakeholders in this process. A brief discussion of these results and a brief enumeration of the next steps for the project will conclude this paper.
The Use of Complementary and Alternative Medicine in Hospitalized Patients with Type 2 Diabetes Mellitus in Israel.

INTRODUCTION
The use of complementary and alternative medicine (CAM) has been on the rise in recent years in the general population, as well as among patients with chronic diseases such as diabetes mellitus. The aim of this study was to add information regarding the use of CAM in patients with type 2 diabetes mellitus (DM2) in Israel and explore possible interactions between CAM and prescription medication (PM).


METHODS
This is a cross-sectional study based on questionnaires. The study included type 2 diabetic patients who were hospitalized in an internal medicine department at Assaf Harofeh Medical Center, Zerifin, Israel, between December 2013 and December 2014. Possible interactions between CAM and PM were evaluated by a clinical pharmacist and a clinical pharmacologist.


RESULTS
Out of 111 diabetic patients, 23.4% used CAM. There was no significant difference between the consumers and nonconsumers in terms of age, education, income, smoking, or alcohol habits. Only 11 of the 26 CAM consumers informed their physician regarding the use. We found possible drug-herb interactions in 19 of the 26 CAM consumers. A major interaction was found between omega-3 and antiaggregants and was encountered in 7 (26.9%) of the CAM consumers. Other minor and major interactions were found with vitamin E, ginkgo-biloba, co-enzyme Q10, green tea, fenugreek seeds, pyridoxine, and dandelion.


CONCLUSIONS
Since CAM consumption is on the rise, it is desirable to improve our knowledge concerning their potential effects and adverse effects, especially in conjunction with PM. Given the complexity of pharmaceutics in patients with chronic diseases, among them patients with DM, the use of supplementary medicine cannot be ignored.
The impact of shiftwork on health: a literature review.

AIMS AND OBJECTIVES
To identify the impact of shiftwork on individuals and their lives and to discuss the implications this has for nurses and nursing.


BACKGROUND
The context of shiftwork in the early 21st century is changing rapidly, and those involved in or required to work shiftwork are now spread over many different sectors of the community. In the Australian community, 16% of workers regularly work shiftwork. Most nurses undertake shiftwork at some time in their career, and health services could not operate without a shiftworking nursing workforce.


DESIGN
Narrative literature review.


METHODS
A narrative review of journal articles was conducted. Databases searched were CINAHL, EBSCO Host, JSTOR, Medline/PubMed and Google Scholar. Search terms used were 'shiftwork' and 'shift work'. Limitations included 'English language', 'published between 1980-2013' and 'human'.


RESULTS
Reviewed for this paper were 118 studies that met the inclusion criteria. Results were categorised using thematic analysis. Themes that emerged were physical and psychosocial health, and sleep. Findings will be explored under these themes.


CONCLUSIONS
Shiftwork research has mainly focussed on the physiological and psychosocial health and sleep effects. Absent from the literature are studies focussing on the personal experience of the shiftworker and how workers mediate the effects of shiftwork and how shiftwork fits into the rest of their lives. Therefore, it is difficult to draw conclusions about how people 'manage' their shiftwork, and further research needs to be undertaken in this area.


RELEVANCE TO CLINICAL PRACTICE
Working shifts for nurses is a reality that comes with the profession. While there is a significant body of research on shiftwork, little of this has been specifically applied to nursing, and the implications for individual nurses needing to care for their own health have not been drawn.
Atrophic gastritis in young children and adolescents.

BACKGROUND
Helicobacter pylori associated gastric cancer arises via a multistage process, with atrophic gastritis being the precursor lesion. Helicobacter pylori is typically acquired in childhood, yet little is known of the prevalence of atrophic gastritis in childhood.


AIM
To study atrophic gastritis among children from countries with high gastric cancer incidence.


METHODS
Sections from topographically mapped gastric biopsy specimens from children undergoing clinically indicated endoscopy in Korea and Colombia were evaluated using visual analogue scales. Atrophy was defined as loss of normal glandular components, including replacement with fibrosis, intestinal metaplasia (IM), and/or pseudopyloric metaplasia of the corpus (identified by the presence of pepsinogen I in mucosa that was topographically corpus but phenotypically antrum).


RESULTS
One hundred and seventy three children, 58 from Korea (median age, 14 years) and 115 from Colombia (median age, 13 years), were studied. Helicobacter pylori was present in 85% of Colombian children versus 17% of Korean children (p<0.01). Atrophic mucosa near the antrum-corpus border was present in 16% of children, primarily as pseudopyloric metaplasia (31%, IM; 63%, pseudopyloric metaplasia; 6%, both). The median age of children with corpus atrophy was 15 (range, 7-17) years.


CONCLUSION
Gastric atrophy occurs in H pylori infected children living in countries with high gastric cancer incidence. Identification and characterisation of the natural history of H pylori gastritis requires targeted biopsies to include the lesser and greater curve of the corpus, starting just proximal to the anatomical antrum-corpus junction, in addition to biopsies targeting the antrum and cardia.
Patterns of User Engagement With the Mobile App, Manage My Pain: Results of a Data Mining Investigation

BACKGROUND
Pain is one of the most prevalent health-related concerns and is among the top 3 most common reasons for seeking medical help. Scientific publications of data collected from pain tracking and monitoring apps are important to help consumers and healthcare professionals select the right app for their use.


OBJECTIVE
The main objectives of this paper were to (1) discover user engagement patterns of the pain management app, Manage My Pain, using data mining methods; and (2) identify the association between several attributes characterizing individual users and their levels of engagement.


METHODS
User engagement was defined by 2 key features of the app: longevity (number of days between the first and last pain record) and number of records. Users were divided into 5 user engagement clusters employing the k-means clustering algorithm. Each cluster was characterized by 6 attributes: gender, age, number of pain conditions, number of medications, pain severity, and opioid use. Z tests and chi-square tests were used for analyzing categorical attributes. Effects of gender and cluster on numerical attributes were analyzed using 2-way analysis of variances (ANOVAs) followed up by pairwise comparisons using Tukey honest significant difference (HSD).


RESULTS
The clustering process produced 5 clusters representing different levels of user engagement. The proportion of males and females was significantly different in 4 of the 5 clusters (all P ≤.03). The proportion of males was higher than females in users with relatively high longevity. Mean ages of users in 2 clusters with high longevity were higher than users from other 3 clusters (all P <.001). Overall, males were significantly older than females (P <.001). Across clusters, females reported more pain conditions than males (all P <.001). Users from highly engaged clusters reported taking more medication than less engaged users (all P <.001). Females reported taking a greater number of medications than males (P =.04). In 4 of 5 clusters, the percentage of males taking an opioid was significantly greater (all P ≤.05) than that of females. The proportion of males with mild pain was significantly higher than that of females in 3 clusters (all P ≤.008).


CONCLUSIONS
Although most users of the app reported being female, male users were more likely to be highly engaged in the app. Users in the most engaged clusters self-reported a higher number of pain conditions, a higher number of current medications, and a higher incidence of opioid usage. The high engagement by males in these clusters does not appear to be driven by pain severity which may, in part, be the case for females. Use of a mobile pain app may be relatively more attractive to highly-engaged males than highly-engaged females, and to those with relatively more complex chronic pain problems.
Robotic surgery in gynecologic oncology.

PURPOSE OF REVIEW
The objective of this article is to review the recently published literature on the use of robotic surgery in the management of gynecologic malignancies.


RECENT FINDINGS
Retrospective data collected from many institutions support the use of robotic surgery in the management of cervical, endometrial, and early-stage ovarian cancer. Benefits to robotic surgery include decreased blood loss, fewer perioperative complications, and decreased length of hospital stay, especially when compared to an open cohort. Disadvantages include costs associated with the robotic system and disposable equipment, accessibility to robotic surgical systems, loss of haptic sensation with the device, and lack of prospective trials validating its use in gynecologic oncology.


SUMMARY
Current evidence establishes a role for the use of robotic surgery in the treatment of gynecologic malignancies. Further research should be implemented to validate the use of robotic surgery in gynecologic malignancies and to compare its outcomes to those of open and laparoscopic surgery.
A Performance Comparison of Fundamental Small-Antenna Designs

In this paper, the performance properties of several fundamental small-antenna designs are compared as a function of overall length and size (ka), where the antennas operate at or very near the same frequency. The objective of this work is to determine which basic design approach or configuration, if any, offers the best performance in terms of: achieving an impedance match; the radiation-pattern shape; the radiation efficiency; the half-power bandwidth; and the 2:1 VSWR bandwidth. The fundamental antenna designs studied here include the spherical folded helix, the cylindrical folded helix, the matched disk-loaded dipole, the matched spherical-cap dipole, and the multi-arm spherical resonator. In addition to discussing the different antenna designs, the fundamental approaches used in impedance matching and optimizing the bandwidth of these small antennas are described. Both numerical simulations and measured results are presented.
Myelination in mouse dorsal root ganglion/Schwann cell cocultures

The established protocols for in vitro studies of peripheral nerve myelination with rat embryonic dorsal root ganglia (DRG) and postnatal Schwann cell cocultures do not work with mouse cells. Consequently, the full potential of this model, which would allow to perform cell type-specific, mixed genotype cocultures without cross-breeding the animals, cannot be exploited. We determined the conditions required to promote full myelination in cocultures of pre-purified mouse embryonic DRG and neonatal Schwann cells, and present a method which consistently yields 50-200 mature myelin sheaths/culture. Causes for the failure of the existing protocols to yield satisfactory results with mouse cells fell into three categories: the lack of adherent support provided by the substratum, growth factor and hormone deficiencies, and the high serum content of the media. For optimal results, mouse cocultures require a 3-dimensional substratum, a myelination-promoting culture medium containing pituitary extract, N2 supplement and forskolin, and a low serum concentration.
Cytoscape Web: an interactive web-based network browser

UNLABELLED
Cytoscape Web is a web-based network visualization tool-modeled after Cytoscape-which is open source, interactive, customizable and easily integrated into web sites. Multiple file exchange formats can be used to load data into Cytoscape Web, including GraphML, XGMML and SIF.


AVAILABILITY AND IMPLEMENTATION
Cytoscape Web is implemented in Flex/ActionScript with a JavaScript API and is freely available at http://cytoscapeweb.cytoscape.org/.
Mathematical Modelling of Wind Turbine in a Wind Energy Conversion System : Power Coefficient Analysis

The world is increasingly going green in its energy use. Wind power is a green renewable source of energy that can compete effectively with fossil fuel as a generator of power in the electricity market. For this effective competion, the production cost must be comparable to that of fossil fuels or other sources of energy. The initial capital investment in wind power goes to machine and the supporting infrastructure. Any factors that lead to decrease in cost of energy such as turbine design, construction and operation are key to making wind power competitive as an alternative source of energy. A mathematical model of wind turbine is essential in the understanding of the behaviour of the wind turbine over its region of operation because it allows for the development of comprehensive control algorithms that aid in optimal operation of a wind turbine. Modelling enables control of wind turbine’s performance. This paper attempts to address part or whole of these general objectives of wind turbine modelling through examination of power coefficient parameter. Model results will be beneficial to designers and researchers of new generation turbines who can utilize the information to optimize the design of turbines and minimize generation costs leading 4528 A. W. Manyonge, R. M. Ochieng, F. N. Onyango and J. M. Shichikha to decrease in cost of wind energy and hence, making it an economically viable alternative source of energy. Mathematics Subject Classification: 65C20