LLukas22/scidocs huggingface dataset:
South Sakhalin Tectonics and geodynamics: a model for the Cretaceous-Paleogene accretion of the East Asian continental margin

[1] This paper presents new data for the geological structure of South Sakhalin which is a connecting link between the structural features of the Sakhalin and Hokkaido islands which form the Late Mesozoic‐Early Cenozoic Hokkaido-Sakhalin fold system. These data were used as a basis for deriving a new model of the tectonic evolution of the region, derived on the basis of terrain analysis. They illustrate the evolution of the East Asia continental margin during the larger part of the Cretaceous and during the Paleogene. The tectonic data available for this region recorded five epochs of structural readjustments, which separated the periods of the accretional growth of the continental margin. It is shown that the geodynamic evolution of the East Asian continental margin was controlled by the combination of convergence and transformation environments at the continent-ocean boundary and was complicated by the accretion of large intraoceanic volcanic rises and by the collision of ensimatic island arcs. INDEX TERMS: 1209 Geodesy and Gravity: Tectonic deformation; 1744 History of Geophysics: Tectonophysics; 3040 Marine Geology and Geophysics: Plate tectonics;
Bilaminar techniques for the treatment of recession-type defects. A comparative clinical study.

OBJECTIVES
Complete root coverage is the primary objective to be accomplished when treating gingival recessions in patients with aesthetic demands. Furthermore, in order to satisfy patient demands fully, root coverage should be accomplished by soft tissue, the thickness and colour of which should not be distinguishable from those of adjacent soft tissue. The aim of the present split-mouth study was to compare the treatment outcome of two surgical approaches of the bilaminar procedure in terms of (i) root coverage and (ii) aesthetic appearance of the surgically treated sites.


MATERIAL AND METHODS
Fifteen young systemically and periodontally healthy subjects with two recession-type defects of similar depth affecting contralateral teeth in the aesthetic zone of the maxilla were enrolled in the study. All recessions fall into Miller class I or II. Randomization for test and control treatment was performed by coin toss immediately prior to surgery. All defects were treated with a bilaminar surgical technique: differences between test and control sites resided in the size, thickness and positioning of the connective tissue graft. The clinical re-evaluation was made 1 year after surgery.


RESULTS
The two bilaminar techniques resulted in a high percentage of root coverage (97.3% in the test and 94.7% in the control group) and complete root coverage (gingival margin at the cemento-enamel junction (CEJ)) (86.7% in the test and 80% in the control teeth), with no statistically significant difference between them. Conversely, better aesthetic outcome and post-operative course were indicated by the patients for test compared to control sites.


CONCLUSIONS
The proposed modification of the bilaminar technique improved the aesthetic outcome. The reduced size and minimal thickness of connective tissue graft, together with its positioning apical to the CEJ, facilitated graft coverage by means of the coronally advanced flap.
Safety and efficacy of lobaplatin combined with 5-fluorouracil as first-line induction chemotherapy followed by lobaplatin-radiotherapy in locally advanced nasopharyngeal carcinoma: preliminary results of a prospective phase II trial

Due to improvements in imaging and radiological techniques as well as the use of chemotherapy, distant metastasis has become the predominant mode of treatment failure in patients with locally advanced nasopharyngeal carcinoma (LA-NPC). Platinum-based systemic chemotherapy has shown survival benefits and is now the standard strategy for systemic therapy in patients with LA-NPC. Notably, the third-generation platinum reagent lobaplatin has shown anti-tumor effects in several solid tumors with lower incidences of gastrointestinal, hepatic and renal toxicity relative to other platinum drugs. However, the safety and efficacy of lobaplatin as a first-line regimen in patients with LA-NPC are undetermined. Patients with stage III–IVa-b NPC received lobaplatin at a dose of 30 mg/m2 on days 1 and 22 combined with a continuous 120-h intravenous injection of 5-fluorouracil at a dose of 4 g/m2 followed by lobaplatin at a dose of 50 mg/m2 on days 43 and 64 concomitant with intensity-modulated radiation therapy. Objective response rates and acute toxicity were assessed based on RECIST (1.1) and CTCAE v.3.0, respectively. Kaplan-Meier analysis was used to calculate survival rates. Fifty-nine patients were enrolled, and 44 patients (74.6%) received allocated cycles of chemotherapy. The objective response rates were 88.1% (95% confidence interval [CI], 0.77 to 0.95) and 100% after induction chemotherapy (ICT) and concurrent chemoradiotherapy (CRT), respectively. With a median follow-up period of 44 months, the 3-year estimated progression-free survival and overall survival were 86.4% (95% CI, 69.8 to 98.8) and 94.9% (95% CI, 89.5 to 100), respectively. The most common grade 3–4 toxicities were neutropenia (8.5%) and thrombocytopenia (40.7%) after ICT and CRT, respectively. Lobaplatin combined with 5-fluorouracil followed by lobaplatin-RT treatment showed encouraging anti-tumor effects with tolerable toxicities in patients with LA-NPC. Randomized controlled trials of lobaplatin in patients with LA-NPC are warranted. This trial was registered with the Chinese Clinical Trials Registry and approved on March 31st, 2012, number ChiCTR-ONC-12002060 .
How Do Investments in Human Capital Differentially Effect Gender Income ? An Analysis of the Gender Wage Gap

This research seeks to determine if equally qualified college-educated men receive more compensation than college-educated women do after several years of experience in the labor force. The empirical model includes several variables to account for investments in human capital, which will help to establish if the individuals are equally qualified. The variables include controls for education, mobility, migration, and area of residence. This article is available in The Park Place Economist: http://digitalcommons.iwu.edu/parkplace/vol8/iss1/14
Space Radiation Risks for Astronauts on Multiple International Space Station Missions

Mortality and morbidity risks from space radiation exposure are an important concern for astronauts participating in International Space Station (ISS) missions. NASA's radiation limits set a 3% cancer fatality probability as the upper bound of acceptable risk and considers uncertainties in risk predictions using the upper 95% confidence level (CL) of the assessment. In addition to risk limitation, an important question arises as to the likelihood of a causal association between a crew-members' radiation exposure in the past and a diagnosis of cancer. For the first time, we report on predictions of age and sex specific cancer risks, expected years of life-loss for specific diseases, and probability of causation (PC) at different post-mission times for participants in 1-year or multiple ISS missions. Risk projections with uncertainty estimates are within NASA acceptable radiation standards for mission lengths of 1-year or less for likely crew demographics. However, for solar minimum conditions upper 95% CL exceed 3% risk of exposure induced death (REID) by 18 months or 24 months for females and males, respectively. Median PC and upper 95%-confidence intervals are found to exceed 50% for several cancers for participation in two or more ISS missions of 18 months or longer total duration near solar minimum, or for longer ISS missions at other phases of the solar cycle. However, current risk models only consider estimates of quantitative differences between high and low linear energy transfer (LET) radiation. We also make predictions of risk and uncertainties that would result from an increase in tumor lethality for highly ionizing radiation reported in animal studies, and the additional risks from circulatory diseases. These additional concerns could further reduce the maximum duration of ISS missions within acceptable risk levels, and will require new knowledge to properly evaluate.
A randomized controlled trial of asthma self-management support comparing clinic-based nurses and in-home community health workers: the Seattle-King County Healthy Homes II Project.

OBJECTIVE
To compare the marginal benefit of in-home asthma self-management support provided by community health workers (CHWs) with standard asthma education from clinic-based nurses.


DESIGN
Randomized controlled trial.


SETTING
Community and public health clinics and homes.


PARTICIPANTS
Three hundred nine children aged 3 to 13 years with asthma living in low-income households.


INTERVENTIONS
All participants received nurse-provided asthma education and referrals to community resources. Some participants also received CHW-provided home environmental assessments, asthma education, social support, and asthma-control resources.


OUTCOME MEASURES
Asthma symptom-free days, Pediatric Asthma Caretaker Quality of Life Scale score, and use of urgent health services.


RESULTS
Both groups showed significant increases in caretaker quality of life (nurse-only group: 0.4 points; 95% confidence interval [CI], 0.3-0.6; nurse + CHW group: 0.6 points; 95% CI, 0.4-0.8) and number of symptom-free days (nurse only: 1.3 days; 95% CI, 0.5-2.1; nurse + CHW: 1.9 days; 95% CI, 1.1-2.8), and absolute decreases in the proportion of children who used urgent health services in the prior 3 months (nurse only: 17.6%; 95% CI, 8.1%-27.2%; nurse + CHW: 23.1%; 95% CI, 13.6%-32.6%). Quality of life improved by 0.22 more points in the nurse + CHW group (95% CI, 0.00-0.44; P = .049). The number of symptom-free days increased by 0.94 days per 2 weeks (95% CI, 0.02-1.86; P = .046), or 24.4 days per year, in the nurse + CHW group. While use of urgent health services decreased more in the nurse + CHW group, the difference between groups was not significant.


CONCLUSION
The addition of CHW home visits to clinic-based asthma education yielded a clinically important increase in symptom-free days and a modest improvement in caretaker quality of life.
Frontal EEG Asymmetry Based Classification of Emotional Valence using Common Spatial Patterns

In this work we evaluate the possibility of predicting the emotional state of a person based on the EEG. We investigate the problem of classifying valence from EEG signals during the presentation of affective pictures, utilizing the ”frontal EEG asymmetry” phenomenon. To distinguish positive and negative emotions, we applied the Common Spatial Patterns algorithm. In contrast to our expectations, the affective pictures did not reliably elicit changes in frontal asymmetry. The classifying task thereby becomes very hard as reflected by the poor classifier performance. We suspect that the masking of the source of the brain activity related to emotions, coming mostly from deeper structures in the brain, and the insufficient emotional engagement are among main reasons why it is difficult to predict the emotional state of a person.
A 144-Mb, eight-level NAND flash memory with optimized pulsewidth programming

We report a fast-programming, compact sense and latch (SL) circuit to realize an eight-level NAND flash memory. Fast programming is achieved by supplying optimized voltage and pulsewidth to the bit lines, according to the programming data. As a result, all data programming is completed almost simultaneously, and 0.67-MB/s program throughput, which is 1.7 times faster than conventional program throughput, is achieved. The compact layout of the SL circuit is made possible by four 3-bit latches sharing one unit of the read/verify control circuit. Using these techniques, we fabricated a 144-Mb, eight-level NAND flash memory using a 0.35-/spl mu/m CMOS process, resulting in a 104.2-mm/sup 2/ die size and a 1.05-/spl mu/m/sup 2/ effective cell size.
An Improved Model for Analysis of Host Network Vulnerability

With all the news on cyber attacks and computer security in the last few years, it does not take much time to realize that some action must be taken to protect our organization before it hits close to our home. In fact, security has gone from backroom to the boardroom in a lightning speed. Network security depends on most of network configuration and vulnerabilities. Each machines overall susceptibility to attack depends upon the vulnerabilities of another machine. An attacker tries to exploit the least secure system by small attacks iteratively, where each exploit in the network provide the platform for subsequent exploit. Such a series is known as attack path and the set of all possible paths will form an attack graph. By their highly interdependencies, it is much complex to draw traditional vulnerability analysis. Several works have been done to construct an attack graphs. The goal of this paper is to provide a framework, architecture, and an intelligent approach to vulnerability analysis by utilizing the concept of automated scanning tools. By the changing environment, conducting a periodic in-house vulnerability assessment is very much essential.
Infants' vagal regulation in the still-face paradigm is related to dyadic coordination of mother-infant interaction.

The authors investigated relations between mother-infant dyadic coordination and infants' physiological responses. Mothers (N=73) and 3-month-old male and female infants were observed in the still-face paradigm, and mothers' and infants' affective states were coded at 1-s intervals. Synchrony and levels of matching between mother-infant affective states were computed, and infants' heart rate and vagal tone were measured. Infants showed increased negative affect and heart rate and decreased vagal tone during mothers' still-face, indicating physiological regulation of distress. Infants who did not suppress vagal tone during the still-face (nonsuppressors) showed less positive affect, higher reactivity and vagal suppression in normal play and reunion episodes, and lower synchrony in normal play with mothers. The results indicate that infants' physiological regulation in social interaction differs in relation to dyadic coordination of affective behaviors.
A frailty index predicts post-liver transplant morbidity and mortality in HIV-positive patients

BACKGROUND
We hypothesized that frailty acts as a measure of health outcomes in the context of LT. The aim of this study was to explore frailty index across LT, as a measure of morbidity and mortality. This was a retrospective observational study including all consecutive 47 HIV+patients who received LT in Modena, Italy from 2003 to June 2015.


METHODS
frailty index (FI) was constructed from 30 health variables. It was used both as a continuous score and as a categorical variable, defining 'most frail' a FI > 0.45. FI change across transplant (deltaFI, ΔFI) was calculated as the difference between year 1 FI (FI-Y1) and pre-transplant FI (FI-t0). The outcomes measures were mortality and "otpimal LT" (defined as being alive without multi-morbidity).


RESULTS
Median value of FI-t0 was 0.48 (IQR 0.42-0.52), FI-Y1 was 0.31 (IQR 0.26-0.41). At year five mortality rate was 45%, "optimal transplant" rate at year 1 was 38%. All the patients who died in the post-LT were most frail in the pre-LT. ΔFI was a predictor of mortality after correction for age and MELD (HR = 1.10, p = 0.006) and was inversely associated with optimal transplant after correction for age (HR = 1.04, p = 0.01).


CONCLUSIONS
We validated FI as a valuable health measure in HIV transplant. In particular, we found a relevant correlation between FI strata at baseline and mortality and a statistically significant correlation between, ΔFI and survival rate.
FROM ASTRONOMY TO HUMANITIES: THE EVOLUTION OF PLANNING FOR THE CAPITAL CITY IN HAN AND TANG DYNASTIES

City is the media of culture, while the capital reflects the cultural style of a nation and people of the very time. The Changan in Han dynasty was built with the idea of the universe. Its planning illustrates the changes from astronomy to humanism.
Graduate students' usage of and attitudes towards e-books: experiences from Taiwan

Purpose – University libraries are increasing their e-book collections. The purpose of this study is to investigate graduate students’ usage of and attitudes towards e-books at National Taiwan University. Design/methodology/approach – A total of 20 graduate students from the fields of humanities, social sciences, science and technology, and medicine were interviewed. Findings – The results indicated that graduate students used e-books mainly for the purposes of study and research. Monographs were the type of e-book that students used most often, followed by textbooks and reference tools. While they appreciated the convenience of using e-books, students mentioned several limitations. They liked the keyword search function of e-books. Most of the time, graduate students browsed a few paragraphs or pages online and then printed out copies for further reading. They also borrowed the corresponding paper versions of the e-books from the library. Students preferred that university libraries supply both the electronic and paper versions. In certain aspects, students’ use behaviour was found to vary among disciplines. Originality/value – This study highlights multiple aspects of graduate students’ use behaviour with respect to e-books. The findings could be used to enhance e-book collection development in university libraries.
Digital control of single-phase UPS inverters with modified PWM technique

The purpose of a voltage controller for UPS inverters is to produce stable output voltage with low distortion under all loading conditions, especially under nonlinear loads and dynamic loads. This paper presents the design of a novel digital robust feedback controller for single-phase UPS inverters based on pole-placement method. With the polynomial design method adopted, all closed-loop poles of the system are placed at origin with feedback of output voltage for achieving fast dynamic response. Furthermore, the feedback of load current is designed so as to reduce the voltage distortion introduced by load current to a small amount so that it can be ignored. To eliminate the effect of the time delay caused by sampling and calculation, a modified PWM technique is introduced. The proposed control strategy is capable of guaranteeing high quality steady-state and dynamic responses. The design of the proposed digital controller is very simple and requires only a reasonably accurate knowledge of the output L-C filter parameters. Also, only the output voltage and load current are sensed. Simulation and experimental verification have been carried out on a 1-kVA PWM inverter. Results of simulations and experiments show that the proposed controller can achieve very low total harmonic distortion (THD) and fast dynamic response under various loads with low switching frequency.
Nonrevascularizable coronary artery disease following coronary artery bypass graft surgery: a population-based study in Olmsted County, Minnesota.

AIMS
Therapeutic options for patients with recurrent cardiac ischemia after coronary artery bypass surgery may be limited and some patients may be considered nonrevascularizable. To further the understanding of this patient cohort, we performed a population-based study of post-coronary bypass patients who developed recurrent angina.


METHODS AND RESULTS
Patients who underwent coronary artery and bypass graft angiography at Mayo Clinic from 2001 to 2005 were identified. Medical records were reviewed to determine indication for angiography, and angiographic analysis was performed in all patients. Among 133 000 residents of Olmsted County, Minnesota, 347 post-bypass patients with angina underwent coronary angiography from 2001 to 2005. Of these, 177 patients received further revascularization (145 percutaneous coronary intervention and 32 redo coronary artery bypass grafting) and the remaining 170 patients were managed medically. Revascularization was not associated with improvement in all-cause or cardiac mortality. Multivariate analysis identified renal dysfunction, diabetes, and severe left ventricular dysfunction but not the lack of revascularization as predictors of mortality.


CONCLUSION
In this population-based study, we identified a yearly incidence range of 17.9-33.2 patients with nonrevascularizable angina after coronary artery bypass grafting per 100 000 population. Further revascularization was not associated with improved mortality or morbidity. Attempts to develop therapeutics for this population must consider the incidence and outcomes of this cohort.
Classification of Cervical Cancer Dataset

ID: 2423 Y. M. S. Al-Wesabi, Avishek Choudhury, Daehan Won Binghamton University, USA
The epidemiology of bacterial vaginosis in relation to sexual behaviour

BACKGROUND
Bacterial vaginosis (BV) has been most consistently linked to sexual behaviour, and the epidemiological profile of BV mirrors that of established sexually transmitted infections (STIs). It remains a matter of debate however whether BV pathogenesis does actually involve sexual transmission of pathogenic micro-organisms from men to women. We therefore made a critical appraisal of the literature on BV in relation to sexual behaviour.


DISCUSSION
G. vaginalis carriage and BV occurs rarely with children, but has been observed among adolescent, even sexually non-experienced girls, contradicting that sexual transmission is a necessary prerequisite to disease acquisition. G. vaginalis carriage is enhanced by penetrative sexual contact but also by non-penetrative digito-genital contact and oral sex, again indicating that sex per se, but not necessarily coital transmission is involved. Several observations also point at female-to-male rather than at male-to-female transmission of G. vaginalis, presumably explaining the high concordance rates of G. vaginalis carriage among couples. Male antibiotic treatment has not been found to protect against BV, condom use is slightly protective, whereas male circumcision might protect against BV. BV is also common among women-who-have-sex-with-women and this relates at least in part to non-coital sexual behaviours. Though male-to-female transmission cannot be ruled out, overall there is little evidence that BV acts as an STD. Rather, we suggest BV may be considered a sexually enhanced disease (SED), with frequency of intercourse being a critical factor. This may relate to two distinct pathogenetic mechanisms: (1) in case of unprotected intercourse alkalinisation of the vaginal niche enhances a shift from lactobacilli-dominated microflora to a BV-like type of microflora and (2) in case of unprotected and protected intercourse mechanical transfer of perineal enteric bacteria is enhanced by coitus. A similar mechanism of mechanical transfer may explain the consistent link between non-coital sexual acts and BV. Similar observations supporting the SED pathogenetic model have been made for vaginal candidiasis and for urinary tract infection.


SUMMARY
Though male-to-female transmission cannot be ruled out, overall there is incomplete evidence that BV acts as an STI. We believe however that BV may be considered a sexually enhanced disease, with frequency of intercourse being a critical factor.