LLukas22/scidocs huggingface dataset:
Recognizing Semantic Features in Faces using Deep Learning

Human face constantly conveys information, both consciously and subconsciously. However, as basic as it is for humans to visually interpret this information, it is quite a big challenge for machines. Conventional semantic facial feature recognition and analysis techniques mostly lack robustness and suffer from high computation time. This paper aims to explore ways for machines to learn to interpret semantic information available in faces in an automated manner without requiring manual design of feature detectors, using the approach of Deep Learning. In this study, the effects of various factors and hyper-parameters of deep neural networks are investigated for an optimal network configuration that can accurately recognize semantic facial features like emotions, age, gender, ethnicity etc. Furthermore, the relation between the effect of high-level concepts on low level features is explored through the analysis of the similarities in low-level descriptors of different semantic features. This paper also demonstrates a novel idea of using a deep network to generate 3-D Active Appearance Models of faces from real-world 2-D images. For a more detailed report on this work, please see [1].
Retrieval Mode Distinguishes the Testing Effect from the Generation Effect.

0749-596X/$ see front matter 2009 Elsevier Inc doi:10.1016/j.jml.2009.11.010 * Corresponding author. Fax: +1 765 496 1264. E-mail address: karpicke@purdue.edu (J.D. Karpi A series of four experiments examined the effects of generation vs. retrieval practice on subsequent retention. Subjects were first exposed to a list of target words. Then the subjects were shown the targets again intact for Read trials or they were shown fragments of the targets. Subjects in Generate conditions were told to complete the fragments with the first word that came to mind while subjects in Recall conditions were told to use the fragments as retrieval cues to recall words that occurred in the first part of the experiment. The instruction manipulated retrieval mode—the Recall condition involved intentional retrieval while the Generate condition involved incidental retrieval. On a subsequent test of free recall or recognition, initial recall produced better retention than initial generation. Both generation and retrieval practice disrupted retention of order information, but retrieval enhanced retention of item-specific information to a greater extent than generation. There is a distinction between the testing effect and the generation effect and the distinction originates from retrieval mode. Intentional retrieval produces greater subsequent retention than generating targets under incidental retrieval instructions. 2009 Elsevier Inc. All rights reserved.
Digital Blur - Creative Practice at the Boundaries of Architecture, Design and Art

Digital Blur brings together some of the world's leading practitioners and thinkers from the fields of art, architecture and design, all of whom share a common desire to exploit the latest computing technologies in their creative practice.
Long-term consistent use of a vaginal microbicide gel among HIV-1 sero-discordant couples in a phase III clinical trial (MDP 301) in rural south-west Uganda

BACKGROUND
A safe and effective vaginal microbicide could substantially reduce HIV acquisition for women. Consistent gel use is, however, of great importance to ensure continued protection against HIV infection, even with a safe and effective microbicide. We assessed the long-term correlates of consistent gel use in the MDP 301 clinical trial among HIV-negative women in sero-discordant couples in south-west Uganda.


METHODS
HIV-negative women living with an HIV-infected partner were enrolled between 2005 and 2008, in a three-arm phase III microbicide trial and randomized to 2% PRO2000, 0.5% PRO2000 or placebo gel arms. Follow-up visits continued up to September 2009. The 2% arm was stopped early due to futility and the 229 women enrolled in this arm were excluded from this analysis. Data were analyzed on 544 women on the 0.5% and placebo arms who completed at least 52 weeks of follow-up, sero-converted or became pregnant before 52 weeks. Consistent gel use was defined as satisfying all of the following three conditions: (i) reported gel use at the last sex act for at least 92% of the 26 scheduled visits or at least 92% of the visits attended if fewer than 26; (ii) at least one used applicator returned for each visit for which gel use was reported at the last sex act; (iii) attended at least 13 visits (unless the woman sero-converted or became pregnant during follow-up). Logistic regression models were fitted to investigate factors associated with consistent gel use.


RESULTS
Of the 544 women, 473 (86.9%) were followed for at least 52 weeks, 29 (5.3%) sero-converted and 42 (7.7%) became pregnant before their week 52 visit. Consistent gel use was reported by 67.8%. Women aged 25 to 34 years and those aged 35 years or older were both more than twice as likely to have reported consistently using gel compared to women aged 17 to 24 years. Living in a household with three or more rooms used for sleeping compared to one room was associated with a twofold increase in consistent gel use.


CONCLUSION
In rural Uganda younger women and women in houses with less space are likely to require additional support to achieve consistent microbicide gel use.


TRIAL REGISTRATION
Protocol Number ISRCTN64716212.
CMOS Voltage and Current Reference Circuits consisting of Subthreshold MOSFETs

The development of ultra-low power LSIs is a promising area of research in microelectronics. Such LSIs would be suitable for use in power-aware LSI applications such as portable mobile devices, implantable medical devices, and smart sensor networks [1]. These devices have to operate with ultra-low power, i.e., a few microwatts or less, because they will probably be placed under conditions where they have to get the necessary energy from poor energy sources such as microbatteries or energy scavenging devices [2]. As a step toward such LSIs, we first need to develop voltage and current reference circuits that can operate with an ultra-low current, several tens of nanoamperes or less, i.e., sub-microwatt operation. To achieve such low-power operation, the circuits have to be operated in the subthreshold region, i.e., a region at which the gate-source voltage of MOSFETs is lower than the threshold voltage [3; 4]. Voltage and current reference circuits are important building blocks for analog, digital, and mixed-signal circuit systems in microelectronics, because the performance of these circuits is determined mainly by their bias voltages and currents. The circuits generate a constant reference voltage and current for various other components such as operational amplifiers, comparators, AD/DA converters, oscillators, and PLLs. For this purpose, bandgap reference circuits with CMOS-based vertical bipolar transistors are conventionally used in CMOS LSIs [5; 6]. However, they need resistors with a high resistance of several hundred megaohms to achieve low-current, subthreshold operation. Such a high resistance needs a large area to be implemented, and this makes conventional bandgap references unsuitable for use in ultra-low power LSIs. Therefore, modified voltage and current reference circuits for lowpower LSIs have been reported (see [7]-[12], [14]-[17]). However, these circuits have various problems. For example, their power dissipations are still large, their output voltages and currents are sensitive to supply voltage and temperature variations, and they have complex circuits with many MOSFETs; these problems are inconvenient for practical use in ultra-low power LSIs. Moreover, the effect of process variations on the reference signal has not been discussed in detail. To solve these problems, I and my colleagues reported new voltage and current reference circuits [13; 18] that can operate with sub-microwatt power dissipation and with low sensitivity to temperature and supply voltage. Our circuits consist of subthreshold MOSFET circuits and use no resistors.
Switching from natalizumab to fingolimod in multiple sclerosis: a French prospective study.

IMPORTANCE
The safety and efficacy of switching from natalizumab to fingolimod have not yet been evaluated in a large cohort of patients with multiple sclerosis (MS) to our knowledge.


OBJECTIVE
To collect data from patients with MS switching from natalizumab to fingolimod.


DESIGN, SETTING, AND PARTICIPANTS
The Enquête Nationale sur l'Introduction du Fingolimod en Relais au Natalizumab (ENIGM) study, a survey-based, observational multicenter cohort study among MS tertiary referral centers. Participants were patients for whom a switch from natalizumab to fingolimod was planned. Clinical data were collected on natalizumab treatment, duration and management of the washout period (WP), and relapse or adverse events during the WP and after the initiation of fingolimod.


MAIN OUTCOMES AND MEASURES
Occurrence of MS relapse during the WP or during a 6-month follow-up period after the initiation of fingolimod.


RESULTS
Thirty-six French MS tertiary referral centers participated. In total, 333 patients with MS switched from natalizumab to fingolimod after a mean of 31 natalizumab infusions (female to male ratio, 2.36; mean age, 41 years; and Expanded Disability Status Scale score at the initiation of natalizumab, 3.6). Seventy-one percent were seropositive for the JC polyomavirus. The Expanded Disability Status Scale score remained stable for patients receiving natalizumab. Twenty-seven percent of patients relapsed during the WP. A WP shorter than 3 months was associated with a lower risk of relapse (odds ratio, 0.23; P = .001) and with less disease activity before natalizumab initiation (P = .03). Patients who stopped natalizumab because of poor tolerance or lack of efficacy also had a higher risk of relapse (odds ratio, 3.20; P = .004). Twenty percent of patients relapsed during the first 6 months of fingolimod therapy. Three percent stopped fingolimod for efficacy, tolerance, or compliance issues. In the multivariate analysis, the occurrence of relapse during the WP was the only significant prognostic factor for relapse during fingolimod therapy (odds ratio, 3.80; P = .05).


CONCLUSIONS AND RELEVANCE
In this study, switching from natalizumab to fingolimod was associated with a risk of MS reactivation during the WP or shortly after fingolimod initiation. The WP should be shorter than 3 months.
Indirect exposure to client trauma and the impact on trainee clinical psychologists: Secondary traumatic stress or vicarious traumatization?

OBJECTIVES
The study investigated the relationship between exposure to trauma work and well-being (general psychological distress, trauma symptoms, and disrupted beliefs) in trainee clinical psychologists. It also assessed the contribution of individual and situational factors to well-being.


DESIGN
A Web-based survey was employed.


METHODS
The survey comprised the General Health Questionnaire, Secondary Traumatic Stress Scale, Trauma and Attachment Belief Scale, Trauma Screening Questionnaire, and specific questions about exposure to trauma work and other individual and situational factors. The link to the online survey was sent via email to trainee clinical psychologists attending courses throughout the UK RESULTS: Five hundred sixty-four trainee clinical psychologists participated. Most trainees had a caseload of one to two trauma cases in the previous 6 months; the most common trauma being sexual abuse. Exposure to trauma work was not related to general psychological distress or disrupted beliefs but was a significant predictor of trauma symptoms. Situational factors contributed to the variance in trauma symptoms; level of stress of clinical work and quality of trauma training were significant predictors of trauma symptoms. Individual and situational factors were also found to be significant predictors of general psychological distress and disrupted beliefs.


CONCLUSIONS
This study provides support for secondary traumatic stress but lacks evidence to support belief changes in vicarious traumatization or a relationship between exposure to trauma work and general psychological distress. The measurement and validity of vicarious traumatization is discussed along with clinical, theoretical implications, and suggestions for future research.


PRACTITIONER POINTS
Secondary traumatic stress is a potential risk for trainee clinical psychologists. Training courses should (a) focus on quality of trauma training as it may be protective; (b) advocate coping strategies to reduce stress of clinical work, as the level of stress of clinical work may contribute to trauma symptoms.


LIMITATIONS INCLUDE
Exposure to trauma work only uniquely explained a small proportion of variance in trauma symptoms. The study was cross-sectional in nature therefore cannot imply causality.
Multimedia document authentication using on-line signatures as watermarks

Authentication of digital documents is an important concern as digital documents are replacing the traditional paper-based documents for official and legal purposes. This is especially true in the case of documents that are exchanged over the Internet, which could be accessed and modified by intruders. The most popular methods used for authentication of digital documents are public key encryption-based authentication and digital watermarking. Traditional watermarking techniques embed a pre-determined character string, such as the company logo, in a document. We propose a fragile watermarking system, which uses an on-line signature of the author as the watermark in a document. The embedding of a biometric characteristic such as signature in a document enables us to verify the identity of the author using a set of reference signatures, in addition to ascertaining the document integrity. The receiver of the document reconstructs the signature used to watermark the document, which is then used to verify the author’s claimed identity. The paper presents a signature encoding scheme, which facilitates reconstruction by the receiver, while reducing the chances of collusion attacks.
Effect of lisdexamfetamine dimesylate on parent-rated measures in children aged 6 to 12 years with attention-deficit/hyperactivity disorder: a secondary analysis.

UNLABELLED
To evaluate the efficacy of lisdexamfetamine dimesylate (LDX) in school-aged children with attention-deficit/hyperactivity disorder (ADHD), using the Conners' Parent Rating Scale, Revised Short Version (CPRS-R:S) and its subscales.


METHODS
This was a secondary post hoc analysis of data from a placebo-controlled, double-blind, parallel-group, forced dose-escalation trial. Boys and girls aged 6 to 12 years with a primary diagnosis of ADHD were randomly assigned to LDX (30, 50, or 70 mg/d) or placebo. Improvement on the CPRS-R:S and its subscales (ADHD Index, hyperactivity, oppositional, and cognition) at 10:00 AM, 2:00 PM, and 6:00 PM was analyzed. Safety assessments included the identification of adverse events and were conducted throughout the study.


RESULTS
Of the 290 patients randomized, 285 were included in the intent-to-treat population. Parents noted significant improvements at all 3 assessment times on the CPRS-R:S total score and for the CPRS-R:S ADHD Index, hyperactivity, and cognition subscales, regardless of the subject baseline disease severity. For the CPRS-R:S oppositional subscale, significant improvement was noted at 10:00 AM and 2:00 PM (P < 0.01), and overall, significant improvement occurred in subjects who were more severely ill at baseline. The tolerability of LDX was comparable to that of other stimulants.


CONCLUSION
Once-daily treatment with LDX was associated with significant improvement in parent-rated assessments of ADHD-related behavior throughout the day at approximately 10:00 AM, 2:00 PM, and 6:00 PM. Lisdexamfetamine dimesylate was effective and well tolerated in this study population of children aged 6 to 12 years with ADHD.
A model of the relationship between psychological characteristics, mobile phone addiction and use of mobile phones by Taiwanese university female students

While many researches have analyzed the psychological antecedents of mobile phone addiction and mobile phone usage behavior, their relationship with psychological characteristics remains mixed. We investigated the relationship between psychological characteristics, mobile phone addiction and use of mobile phones for 269 Taiwanese female university students who were administered Rosenberg’s selfesteem scale, Lai’s personality inventory, and a mobile phone usage questionnaire and mobile phone addiction scale. The result showing that: (1) social extraversion and anxiety have positive effects on mobile phone addiction, and self-esteem has negative effects on mobile phone addiction. (2) Mobile phone addiction has a positive predictive effect on mobile phone usage behavior. The results of this study identify personal psychological characteristics of Taiwanese female university students which can significantly predict mobile phone addiction; female university students with mobile phone addiction will make more phone calls and send more text messages. These results are discussed and suggestions for future research for school and university students are provided. 2012 Elsevier Ltd. All rights reserved.
On the Complexity of Teaching

While most theoretical work in machine learning has focused on the complexity of learning, recently there has been increasing interest in formally studying the complexity of teaching . In this paper we study the complexity of teaching by considering a variant of the on-line learning model in which a helpful teacher selects the instances. We measure the complexity of teaching a concept from a given concept class by a combinatorial measure we call the teaching dimension. Informally, the teaching dimension of a concept class is the minimum number of instances a teacher must reveal to uniquely identify any target concept chosen from the class. A preliminary version of this paper appeared in the Proceedings of the Fourth Annual Workshop on Computational Learning Theory, pages 303{314. August 1991. Most of this research was carried out while both authors were at MIT Laboratory for Computer Science with support provided by ARO Grant DAAL03-86-K-0171, DARPA Contract N00014-89-J-1988, NSF Grant CCR-88914428, and a grant from the Siemens Corporation. S. Goldman is currently supported in part by a G.E. Foundation Junior Faculty Grant and NSF Grant CCR-9110108.
Bound states of massless fermions as a source for new physics

The contribution of interactions at short and large distances to particle masses is discussed in the framework of the standard model.
Relationship Satisfaction : The influence of Attachment , Love Styles and Religiosity

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Internal friction in WC-Co hard metals☆

Abstract Internal friction measurements have been performed on various grades of WC-Co cemented carbides from room temperature to 1000°C. These composite materials exhibit an internal friction spectrum which is mainly composed of a relaxation peak and a high temperature exponential background. The peak appears in the same temperature range where an increase in toughness has been observed and interpreted as being due to a brittle-to-ductile transition of the material. The exponential background can be associated with high temperature creep phenomena. The analysis of the results obtained shows the important role of the cobalt binder phase in the mechanical behaviour of WC-Co.
A flexible approach for abstracting and personalizing large business process models

In process-aware information systems (PAISs), usually, different user groups have distinguished perspectives on the business processes supported and on related business data. Hence, personalized views and proper abstractions on these business processes are needed. However, existing PAISs do not provide adequate mechanisms for creating and visualizing process views and process model abstractions. Usually, process models are displayed to users in exactly the same way as originally modeled. This paper presents a flexible approach for creating personalized views based on parameterizable operations. Respective view creation operations can be flexibly composed to either hide non-relevant process information or to abstract it. Depending on the parameterization of the selected view creation operations, one obtains process views with more or less relaxed properties, e.g., regarding the degree of information loss or the soundness of the resulting model abstractions. Altogether, the realized view concept allows for a more flexible abstraction and visualization of large business process models satisfying the needs of different user groups.
A randomized phase II study comparing erlotinib versus erlotinib with alternating chemotherapy in relapsed non-small-cell lung cancer patients: the NVALT-10 study.

BACKGROUND
Epidermal growth factor receptor tyrosine kinase inhibitors (TKIs) administered concurrently with chemotherapy did not improve outcome in non-small-cell lung cancer (NSCLC). However, in preclinical models and early phase noncomparative studies, pharmacodynamic separation of chemotherapy and TKIs did show a synergistic effect.


PATIENTS AND METHODS
A randomized phase II study was carried out in patients with advanced NSCLC who had progressed on or following first-line chemotherapy. Erlotinib 150 mg daily (monotherapy) or erlotinib 150 mg during 15 days intercalated with four 21-day cycles docetaxel for squamous (SQ) or pemetrexed for nonsquamous (NSQ) patients was administered (combination therapy). After completion of chemotherapy, erlotinib was continued daily. Primary end point was progression-free survival (PFS).


RESULTS
Two hundred and thirty-one patients were randomized, 115 in the monotherapy arm and 116 in the combination arm. The adjusted hazard ratio for PFS was 0.76 [95% confidence interval (CI) 0.58-1.02; P = 0.06], for overall survival (OS) 0.67 (95% CI 0.49-0.91; P = 0.01) favoring the combination arm. This improvement was primarily observed in NSQ subgroup. Common Toxicity Criteria grade 3+ toxic effect occurred in 20% versus 56%, rash in 7% versus 15% and febrile neutropenia in 0% versus 6% in monotherapy and combination therapy, respectively.


CONCLUSIONS
PFS was not significantly different between the arms. OS was significantly improved in the combination arm, an effect restricted to NSQ histology.


STUDY REGISTRATION NUMBER
NCT00835471.