LLukas22/scidocs huggingface dataset:
Design of emerging digital services: a taxonomy

Received: 26 April 2008 Accepted: 4 September 2008 Abstract There has been a gigantic shift from a product based economy to one based on services, specifically digital services. From every indication it is likely to be more than a passing fad and the changes these emerging digital services represent will continue to transform commerce and have yet to reach market saturation. Digital services are being designed for and offered to users, yet very little is known about the design process that goes behind these developments. Is there a science behind designing digital services? By examining 12 leading digital services, we have developed a design taxonomy to be able to classify and contrast digital services. What emerged in the taxonomy were two broad dimensions; a set of fundamental design objectives and a set of fundamental service provider objectives. This paper concludes with an application of the proposed taxonomy to three leading digital services. We hope that the proposed taxonomy will be useful in understanding the science behind the design of digital services. European Journal of Information Systems (2008) 17, 505–517. doi:10.1057/ejis.2008.38
Postprandial lipid and carbohydrate responses after the ingestion of a casein-enriched mixed meal.

BACKGROUND
Postprandial lipemia is markedly modulated when carbohydrates are added to a fatty meal. The effect of added protein is less known, however, and the data are controversial.


OBJECTIVE
We investigated the effects of casein added to various fat-rich meals in the absence and presence of oligosaccharides.


DESIGN
Four different test meals were given to 24 healthy volunteers: 1) fat alone, consisting of 3 g cream/kg body wt; 2) fat plus 75 g oligosaccharides; 3) fat plus 50 g sodium caseinate; and 4) a combination of all 3 components. Blood samples were taken before the meals and 1, 2, 3, 4, 5, 6, 7, and 8 h thereafter. The variables measured were serum free fatty acids, arginine, glucose, insulin, and C-peptide as well as triacylglycerol in serum, in chylomicrons, and in VLDL. Gastric emptying was monitored with the use of a (13)C breath test.


RESULTS
Addition of oligosaccharides resulted in the known delay and reduction in postprandial lipemia. Casein caused additional effects: chylomicrons were further reduced and delayed, independently of gastric emptying. C-peptide and insulin, as expressed by their areas under the curves, were raised not only during the early response to the glucose load but also in the postabsorptive state. Concentrations of free fatty acids, which were markedly suppressed by 24% after oligosaccharides alone, were lowered a further 20% after the addition of casein.


CONCLUSIONS
Casein added to a fatty meal lowers free fatty acids markedly in the postprandial and postabsorption phases, probably via its insulinotropic activity. Postprandial lipemia is also moderately reduced.
The use of the Mini-Nutritional Assessment (MNA) tool in elderly orthopaedic patients

Objective: To assess the use of the Mini-Nutritional Assessment (MNA) in elderly orthopaedic patients.Design: An observation study assessing the nutritional status of female orthopaedic patients.Setting: The orthopaedic wards of the Royal Surrey County Hospital.Subjects: Forty-nine female patients aged 60–103 y; dietary records were obtained for 41 subjects and 36 subjects gave a blood sample for biochemical analysis.Major outcome methods: MNA questionnaire, anthropometry, plasma albumin, transferrin, C-reactive protein (CRP) levels and dietary analyses.Results: The group as a whole had low mean values for body weight, albumin and transferrin and high CRP levels. In addition, the group had mean energy intakes well below the estimated average requirement (EAR) and mean intakes of vitamin D, magnesium, potassium, selenium and non-starch polysaccharides (NSP) were below the lower reference nutrient intakes (LRNI). The MNA screening section categorized 69% of the patients as requiring a full assessment (scored 11 or below), but for the purposes of the study the MNA was completed on all patients. The MNA assessment categorized 16% of the group as ‘malnourished’ (scored<17 points), 47% as ‘at risk’ (scored 17.5–23.5) and 37% as ‘well nourished’ (scored>23.5). Significant differences were found between the malnourished and well nourished groups for body weight (P<0.001), body mass index (BMI) (P<0.001), demiquet (P<0.001) and mindex (P<0.001). Mean values for energy and nutrient intakes showed a clear stepwise increase across the three groups for all nutrients except sodium, with significant differences for protein (P<0.05), carbohydrate (P<0.05), riboflavin (P<0.05) niacin (P<0.05), pyridoxine (P<0.05), folate (P<0.05), calcium (P<0.05), selenium (P<0.05), iron (P<0.05) and NSP (P<0.05) intakes. Stepwise multiple regression analysis indicated that anthropometric assessments were the most predictive factors in the total MNA score. The sensitivity and specificity of the MNA was assessed in comparison with albumin levels, energy intake and mindex. The sensitivity of the MNA classification of those scoring less than 17 points in comparison with albumin levels, energy intake and mindex varied from 27 to 57% and the specificity was 66–100%. This was compared with the sensitivity and specificity of using a score of less than 23.5 on the MNA to predict malnourished individuals. Using this cut-off the sensitivity ranged from 75 to 100%, but the specificity declined to between 37 and 50%.Conclusions: The results suggest that the MNA is a useful diagnostic tool in the identification of elderly patients at risk from malnutrition and those who are malnourished in this hospital setting.Sponsorship: Nestlé Clinical Nutrition, Croydon, Surrey.European Journal of Clinical Nutrition (2000) 54, 555–562
Observation of strong coupling between one atom and a monolithic microresonator

Over the past decade, strong interactions of light and matter at the single-photon level have enabled a wide set of scientific advances in quantum optics and quantum information science. This work has been performed principally within the setting of cavity quantum electrodynamics with diverse physical systems, including single atoms in Fabry–Perot resonators, quantum dots coupled to micropillars and photonic bandgap cavities and Cooper pairs interacting with superconducting resonators. Experiments with single, localized atoms have been at the forefront of these advances with the use of optical resonators in high-finesse Fabry–Perot configurations. As a result of the extreme technical challenges involved in further improving the multilayer dielectric mirror coatings of these resonators and in scaling to large numbers of devices, there has been increased interest in the development of alternative microcavity systems. Here we show strong coupling between individual caesium atoms and the fields of a high-quality toroidal microresonator. From observations of transit events for single atoms falling through the resonator's evanescent field, we determine the coherent coupling rate for interactions near the surface of the resonator. We develop a theoretical model to quantify our observations, demonstrating that strong coupling is achieved, with the rate of coherent coupling exceeding the dissipative rates of the atom and the cavity. Our work opens the way for investigations of optical processes with single atoms and photons in lithographically fabricated microresonators. Applications include the implementation of quantum networks, scalable quantum logic with photons, and quantum information processing on atom chips.
The Use of Human Deoxyribonuclease (rhDNase) in the Management of Cystic Fibrosis

In patients with cystic fibrosis (CF), the poor clearance of airway secretions promotes recurrent cycles of pulmonary infection and inflammation. In recent years, novel drugs have been developed to alter the properties of the secretions in an attempt to aid chest physiotherapy in improving airway clearance. Once-daily nebulised recombinant human deoxyribonuclease (rhDNase; dornase alfa; Pulmozyme®) is the most widely used mucoactive therapy in patients with CF. It has been shown to reduce the viscoelasticity of sputum from patients with CF and enhance the clearance of secretions. Clinical trials have shown rhDNase to be a well tolerated treatment that improves pulmonary function and reduces respiratory exacerbations. However, the response to treatment is heterogeneous and only a proportion of patients with CF actually benefit from the treatment. At present, we are unable to predict which patients will benefit from rhDNase. Many CF centers have developed formal n-of-1 trials of treatment to find out who benefits and to justify prescribing the agent. rhDNase is an expensive therapy and is mainly used in patients over the age of 5 years with moderate to severe lung disease. However, studies have shown that rhDNase may be useful in patients with milder lung disease. Comparisons with another mucoactive drug, hypertonic saline, have shown rhDNase to be more effective. Recently, it has been shown that giving rhDNase on an alternate-day basis, rather than daily, is equally effective, potentially reducing costs and treatment time.
Dengue Knowledge and Preventive Practices among Rural Residents in Samar Province, Philippines

The World Health Organization (WHO) classifies dengue as a disease important in public health. The epidemiology and ecology of dengue infections are strongly associated with human habits and activities. The present study aimed to evaluate the knowledge and practices regarding dengue infections among rural residents in Samar Province, Philippines. A cross sectional design was adopted for this investigation. Convenience samples of six hundred forty six (646) residents who were visiting the rural health units in different municipalities of Samar, Philippines were taken as participants in study. More than half of the respondents had good knowledge (61.45%) on causes, signs and symptoms, mode of transmission, and preventive measures about dengue. More than half of the respondents used dengue preventive measures such as fans (n = 340, 52.63%), mosquito coil (n = 458, 70.90%), and bed nets (n = 387, 59.91%) to reduce mosquitoes while only about one third utilized insecticides sprays (n = 204, 31.58%) and screen windows (n = 233, 36.07%) and a little portion used professional pest control (n = 146, 22.60%). There was no correlation between knowledge about dengue and preventive practices (p=0.75). Television/Radio was cited as the main source of information on dengue infections. Findings suggest that better knowledge does not necessarily lead to better practice of dengue measures. Educational campaigns should give more emphasis dengue transmissions and on cost effective ways of reducing mosquito and preventing dengue such as environmental measures and control. Furthermore, wide range of information, skills and support must be provided by the government to increase dengue awareness among residents.
Resource Allocation for Delay-Sensitive Traffic Over LTE-Advanced Relay Networks

Future wireless networks will face the dual challenge of supporting large traffic volumes while providing reliable service for delay-sensitive traffic. To meet the challenge, relay network has been introduced as a new network architecture for the fourth generation (4G) LTE-Advanced (LTE-A) networks. In this paper, we investigate resource allocation including subcarrier and power allocation for LTE-A relay networks under statistical quality of service (QoS) constraints. By dual decomposition, we derive the optimal subcarrier and power allocation strategies to maximize the effective capacity (EC) of the underlying LTE-A relay systems. Characteristics of optimal resource allocation strategies are identified, and a low-complexity suboptimal scheme is developed through optimizing the subcarrier and power allocation individually. Our result suggests that the optimal subcarrier and power allocation strategies depend heavily on the underlying QoS constraint. For example, in the low signal-to-interference-plus-noise (SINR) regime, when there are less stringent QoS constraints, base stations and relay stations tend to allocate all the power to the best available subcarrier. However, as QoS requirements become more stringent, both base stations and relay stations will spread their power over available subcarriers. On the other hand, in the high SINR regime, regardless of the QoS constraints, base stations and relay stations tend to equally allocate power among available subcarriers.
Effect of hyperoxia on gas exchange and lactate kinetics following exercise onset in nonhypoxemic COPD patients.

STUDY OBJECTIVES
The slow oxygen uptake (VO(2)) kinetics observed in COPD patients is a manifestation of skeletal muscle dysfunction of multifactorial origin. We determined whether oxygen supplementation during exercise makes the dynamic VO(2) response faster and reduces transient lactate increase.


DESIGN
Ten patients with severe COPD (ie, mean [+/- SD] FEV(1), 31 +/- 10% predicted) and 7 healthy subjects of similar age performed four repetitions of the transition between rest and 10 min of moderate-intensity, constant-work rate exercise while breathing air or 40% oxygen in random order. Minute ventilation (VE), gas exchange, and heart rate (HR) were recorded breath-by-breath, and arterialized venous pH, PCO(2), and lactate levels were measured serially.


RESULTS
Compared to healthy subjects, the time constants (tau) for VO(2), HR, carbon dioxide output (VCO(2)), and VE kinetic responses were significantly slower in COPD patients than in healthy subjects (70 +/- 8 vs 44 +/- 3 s, 98 +/- 14 vs 44 +/- 8 s, 86 +/- 8 vs 61 +/- 4 s, and 81 +/- 7 vs 62 +/- 4 s, respectively; p < 0.05). Hyperoxia decreased end-exercise E in the COPD group but not the healthy group. Hyperoxia did not increase the speed of VO(2) kinetics but significantly slowed VCO(2) and E response dynamics in both groups. Only small increases in lactate occurred with exercise, and this increase did not correlate with the tau for VO(2).


CONCLUSION
In nonhypoxemic COPD patients performing moderate exercise, the lower ventilatory requirement induced by oxygen supplementation is not related to improved muscle function but likely stems from direct chemoreceptor inhibition.
Aspirin administration for cardiac-related acute chest pain/angina: increased use in Medicare patients.

BACKGROUND
Coronary heart disease (CHD), the leading cause of death in the United States, accounted for approximately 490,000 deaths in 1993. Angina pectoris, a manifestation of CHD, accounted for 13,586 Medicare discharges in 1993 in Texas. A pilot project showed aspirin prophylaxis that reduces cardiovascular morbidity and mortality in individuals with acute angina is underused. Texas Medical Foundation collaborated with 10 acute-care facilities to improve aspirin prophylaxis.


METHODS
Collaborators assessed processes of care and implemented clinical pathways to improve aspirin administration. Data were abstracted from medical records before and after pathway implementation to evaluate impact.


RESULTS
Aspirin administration during hospital stay increased 10.8%, aspirin administration on discharge increased 11.7%, and average time from arrival to aspirin administration decreased 2.9 hours.


CONCLUSIONS
Results suggest collaborator-implemented clinical pathways significantly improved care received by Medicare patients admitted for cardiac-related acute chest pain/angina. Data suggest room for further improvement.
Gender and the nocebo response following conditioning and expectancy.

OBJECTIVE
To investigate the role of Pavlovian conditioning and expectancy and of gender on the nocebo effects.


METHODS
Conditioning experiment: Forty-eight healthy male and female volunteers were investigated for 3 days using a standard rotation procedure. Subjects in the experimental group received a salient oral stimulus prior to rotation; subjects in the control group received the stimulus 12 h after rotations on Days 1 and 2; on Day 3, all subjects received the stimulus prior to rotation. Expectancy experiment: Another 48 healthy subjects were rotated 5 x 1 min once only. All subjects received the same oral stimulus immediately prior to rotation; subjects in the experimental group were told that the symptoms might worsen with the stimulus; controls did not receive additional information. In both experiments, symptom rating (SR) and rotation tolerance (RT) were determined.


RESULTS
Conditioning significantly reduced RT (P=.015) and increased SR (P=.024). For both RT and SR, a significant "day x group x gender" effect was found (P=.044; SR: P=.011) indicating that conditioning was more effective in women. Expectancies lowered RT (P=.085) without affecting SR. There was a significant "rotation x gender" interaction on RT (P=.005) indicating that the expectancy was more effective in men.


CONCLUSION
Women responded stronger to conditioning while men responded to expectancies, but to a lesser degree. It needs to be determined whether this is restricted to nausea-specific conditions or can be generalized across clinical and experimental conditions.
The Temporality of the Public Sphere : Orpheus Descending s Loop between Art and Culture

Over the summer of 2000, the artist Paul Pfeiffer, with his collaborators John Letourneau and Lawrence Chua, videotaped a flock of chickens on a farm in upstate New York. Using three still cameras, they followed the birds lives twentyfour hours a day: beginning with incubated eggs purchased from a local supplier, through hatching at around seventeen days, to the flocks move to its outdoor pen, and ending when the chickens reached adulthood, on the seventy-fifth day.1 From April 15 to June 28, 2001, Paul Pfeiffers Orpheus Descendingthe work that resulted from this footagewas simultaneously shown on two of the information plasma screens and video monitors found throughout the public thoroughfares of the World Trade Center and the World Financial Center complex. The first, a PATHVISION information monitor wedged between a Hudson newsstand and a Quick Card machine [Fig. 1], was located in the mezzanine defined by a bank of nineteen escalators and the New Jersey PATH train turnstiles [Fig. 2]. The second was a plasma screen that placed the video between directional signage and advertisements promoting local businesses and cultural events on the North Bridge, a glass-enclosed pedestrian overpass spanning the World Financial Center and the World Trade Center [Fig. 3].
Internet of Things: A survey on architecture, technologies, protocols and challenges

Internet of Things (IoT) can be thought of as the next big step in internet technology. It is enabled by the latest developments in communication technologies and internet protocols. This paper surveys IoT in respect of layer architecture, enabling technologies, related protocols and challenges.
Left ventricular longitudinal strain by speckle-tracking echocardiography is associated with treatment-requiring cardiac allograft rejection.

BACKGROUND
Noninvasive detection of rejection is a major objective in the management of heart transplant recipients.


METHODS AND RESULTS
To investigate the utility of 2-dimensional speckle-tracking echocardiography (2D-STE), we retrospectively evaluated 160 sets of endomyocardial biopsies and echocardiograms from 59 asymptomatic heart transplant recipients. Conventional International Society for Heart and Lung Transplantation grade 1B or higher rejection was considered as treatment-requiring rejection (group R), whereas International Society for Heart and Lung Transplantation grade 0 or 1A was classified as group Non-R. Left ventricular global longitudinal strain (GLS), global circumferential strain, and global radial strain were assessed by 2D-STE. Twenty-five specimens were classified into group R. GLS was significantly associated with treatment-requiring rejection, whereas neither global radial strain nor global circumferential strain were. Lower GLS remained significantly associated with an increased risk of treatment-requiring rejection (odds ratio, 1.15 [95% CI, 1.01-1.30]; P=0.03) even in multivariate analysis. GLS with the absolute value of less than 14.8% showed sensitivity and specificity of 64% and 63%, respectively, for detection of treatment-requiring rejection.


CONCLUSION
The 2D-STE-derived left ventricular GLS was associated with treatment-requiring rejection. Two-dimensional STE might be useful as a noninvasive supplemental tool for monitoring heart transplant recipients for possible treatment-requiring rejection.
Validity of covering-up sun-protection habits: Association of observations and self-report.

BACKGROUND
Few studies have reported the accuracy of measures used to assess sun-protection practices. Valid measures are critical to the internal validity and use of skin cancer control research.


OBJECTIVES
We sought to validate self-reported covering-up practices of pool-goers.


METHODS
A total of 162 lifeguards and 201 parent/child pairs from 16 pools in 4 metropolitan regions in the United States completed a survey and a 4-day sun-habits diary. Observations of sun-protective behaviors were conducted on two occasions.


RESULTS
Agreement between observations and diaries ranged from slight to substantial, with most values in the fair to moderate range. Highest agreement was observed for parent hat use (kappa = 0.58-0.70). There was no systematic pattern of over- or under-reporting among the 3 study groups.


LIMITATIONS
Potential reactivity and a relatively affluent sample are limitations.


CONCLUSION
There was little over-reporting and no systematic bias, which increases confidence in reliance on verbal reports of these behaviors in surveys and intervention research.
Socio-cultural aspects of information technology in Africa. The policy of the World Bank Studies on Media Information and Telecommunication (SMIT)

ABSTRACT The World Bank is an important actor in the implementation of new information technologies (ITs) in Africa by means of loans to governments and support to private companies. Its policy is guided mainly by techno-economical aspects. The intended target group's socio-cultural context is hardly taken into consideration. Critics argue that the Bank's policy has resulted in inappropriate technology, ignorance of the African user and a reinforcement of Western elites. The World Bank's approach is embedded in a Western worldview, in which privatisation and liberalisation are the keywords. In this technology-driven view, IT is supposed to solve all kinds of problems, including socio-cultural problems, hence socio-cultural aspects are regarded as less important. Nevertheless, some recent documents of the World Bank indicate a growing interest in those aspects. Time will show whether we can label that discourse a neo-liberal doctrine embellished with some socio-cultural hot topics. This article is based on...
Everyday making: identifying future uses for 3D printing in the home

Low-cost and commercially available 3D printers are predicted to be the next disruptive innovation in technology. However, little research has examined how non-designers might interact with fabrication tools in their homes. To explore the potential uses of 3D printers and other fabrication devices in the home, we conducted a study in which 10 households (with 28 individuals) kept a faux 3D printer in their homes for four weeks. Participants kept a log of items that they would want to print, and completed a series of design probes. We found that participants' use of the fabrication tools involved three activities: replicating existing objects, modifying and customizing existing objects, and creating new custom objects. Our study also provides insights on the types of objects that individuals wish to create, and how the faux 3D printer was situated in our participants' homes.