LLukas22/scidocs huggingface dataset:
Total transcriptome, proteome, and allergome of Johnson grass pollen, which is important for allergic rhinitis in subtropical regions.

BACKGROUND
Genomic data are lacking for many allergen sources. To circumvent this limitation, we implemented a strategy to reveal the repertoire of pollen allergens of a grass with clinical importance in subtropical regions, where an increasing proportion of the world's population resides.


OBJECTIVE
We sought to identify and immunologically characterize the allergenic components of the Panicoideae Johnson grass pollen (JGP; Sorghum halepense).


METHODS
The total pollen transcriptome, proteome, and allergome of JGP were documented. Serum IgE reactivities with pollen and purified allergens were assessed in 64 patients with grass pollen allergy from a subtropical region.


RESULTS
Purified Sor h 1 and Sor h 13 were identified as clinically important allergen components of JGP with serum IgE reactivity in 49 (76%) and 28 (43.8%), respectively, of patients with grass pollen allergy. Within whole JGP, multiple cDNA transcripts and peptide spectra belonging to grass pollen allergen families 1, 2, 4, 7, 11, 12, 13, and 25 were identified. Pollen allergens restricted to subtropical grasses (groups 22-24) were also present within the JGP transcriptome and proteome. Mass spectrometry confirmed the IgE-reactive components of JGP included isoforms of Sor h 1, Sor h 2, Sor h 13, and Sor h 23.


CONCLUSION
Our integrated molecular approach revealed qualitative differences between the allergenic components of JGP and temperate grass pollens. Knowledge of these newly identified allergens has the potential to improve specific diagnosis and allergen immunotherapy treatment for patients with grass pollen allergy in subtropical regions and reduce the burden of allergic respiratory disease globally.
The Concordance between Patients’ Renal Replacement Therapy Choice and Definitive Modality: Is It a Utopia?

INTRODUCTION
It is desirable for patients to play active roles in the choice of renal replacement therapy (RRT). Patient decision aid tools (PDAs) have been developed to allow the patients to choose the option best suited to their individual needs.


MATERIAL AND METHODS
An observational, prospective registry was conducted in 26 Spanish hospitals between September 2010 and May 2012. The results of the patients' choice and the definitive RRT modality were registered through the progressive implementation of an Education Process (EP) with PDAs designed to help Chronic Kidney Disease (CKD) patients choose RRT.


RESULTS
Patients included in this study: 1044. Of these, 569 patients used PDAs and had made a definitive choice by the end of registration. A total of 88.4% of patients chose dialysis [43% hemodialysis (HD) and 45% peritoneal dialysis (PD)] 3.2% preemptive living-donor transplant (TX), and 8.4% conservative treatment (CT). A total of 399 patients began RRT during this period. The distribution was 93.4% dialysis (53.6% HD; 40% PD), 1.3% preemptive TX and 5.3% CT. The patients who followed the EP changed their mind significantly less often [kappa value of 0.91 (95% CI, 0.86-0.95)] than those who did not follow it, despite starting unplanned treatment [kappa value of 0.85 (95% CI, 0.75-0.95]. A higher agreement between the final choice and a definitive treatment was achieved by the EP and planned patients [kappa value of 0.93 (95% CI, 0.89-0.98)]. Those who did not go through the EP had a much lower index of choosing PD and changed their decision more frequently when starting definitive treatment [kappa value of 0.73 (95% CI, 0.55-0.91)].


CONCLUSIONS
Free choice, assisted by PDAs, leads to a 50/50 distribution of PD and HD choice and an increase in TX choice. The use of PDAs, even with an unplanned start, achieved a high level of concordance between the chosen and definitive modality.
Strong Cosmic Censorship for T2-Symmetric Spacetimes with Cosmological Constant and Matter

Abstract.We address the issue of strong cosmic censorship for T2-symmetric spacetimes with positive cosmological constant. In the case of collisionless matter, we complete the proof of the C2 formulation of the conjecture for this class of spacetimes. In the vacuum case, we prove that the conjecture holds for the special cases where the area element of the group orbits does not vanish on the past boundary of the maximal Cauchy development.
Amitriptyline and aerobic exercise or amitriptyline alone in the treatment of chronic migraine: a randomized comparative study.

UNLABELLED
To compare the preventive treatment benefits of amitriptyline and aerobic exercise or amitriptyline alone in patients with chronic migraine.


METHOD
Sixty patients, both genders, aged between 18 and 50 years, with a diagnosis of chronic migraine, were randomized in groups called amitriptyline and aerobic exercise or amitriptyline alone. The following parameters were evaluated: headache frequency, intensity and duration of headache, days of the analgesic medication use, body mass index (BMI), Beck Depression Inventory (BDI) and Beck Anxiety Inventory (BAI) scores.


RESULTS
In the evaluated parameters, was observed decrease in headache frequency (p=0.001), moderate intensity (p=0.048), in headache duration (p=0.001), the body mass index (p=0.001), Beck Depression Inventory (p=0.001) and Beck Anxiety Inventory scores (p=0.001), when groups were compared in the end of third month.


CONCLUSION
In this study, the amitriptyline was an effective treatment for chronic migraine, but its efficacy was increased when combined with aerobic exercise.
Diurnal Variation of Rain Attenuation Obtained From Measurement of Raindrop Size Distribution in Equatorial Indonesia

The measured rain rate, raindrop size distribution (DSD), and the ITU-R model over the frequency range from 1-100 GHz have been used to elucidate the cumulative rainfall rate and the variability of rain attenuation at Kototabang. Rain rate and DSD are recorded from ground-based optical rain gauge and disdrometer measurements, respectively. Considerable differences between the recorded data and the ITU-R model are observed at small time percentage. The specific rain attenuation obtained from the DSD measurement shows diurnal variation with the largest attenuation observed in the morning hours. This characteristic is due to the raindrop spectra of rain events in this period containing more small-sized drops (<2 mm) than at others as described by the largest contribution of these drops on the specific rain attenuation. The diurnal variation is serious for frequencies higher than 60 GHz especially in very extreme rain.
The Spline-Garch Model for Low Frequency Volatility and its Global Macroeconomic Causes

Twenty-five years of volatility research has left the macroeconomic environment playing a minor role. This paper proposes modeling equity volatilities as a combination of macroeconomic effects and time series dynamics. High frequency return volatility is specified to be the product of a slow-moving component, represented by an exponential spline, and a unit GARCH. This slowmoving component is the low frequency volatility, which in this model coincides with the unconditional volatility. This component is estimated for nearly 50 countries over various sample periods of daily data. Low frequency volatility is then modeled as a function of macroeconomic and financial variables in an unbalanced panel with a variety of dependence structures. It is found to vary over time and across countries. The low frequency component of volatility is greater when the macroeconomic factors GDP, inflation, and short-term interest rates are more volatile or when inflation is high and output growth is low. Volatility is higher for emerging markets and for markets with small numbers of listed companies and market capitalization relative to GDP, but also for large economies. The model allows long horizon forecasts of volatility to depend on macroeconomic developments, and delivers estimates of the volatility to be anticipated in a newly opened market.
Variability in prostate and seminal vesicle delineations defined on magnetic resonance images, a multi-observer, -center and -sequence study

BACKGROUND
The use of magnetic resonance (MR) imaging as a part of preparation for radiotherapy is increasing. For delineation of the prostate several publications have shown decreased delineation variability using MR compared to computed tomography (CT). The purpose of the present work was to investigate the intra- and inter-physician delineation variability for prostate and seminal vesicles, and to investigate the influence of different MR sequence settings used clinically at the five centers participating in the study.


METHODS
MR series from five centers, each providing five patients, were used. Two physicians from each center delineated the prostate and the seminal vesicles on each of the 25 image sets. The variability between the delineations was analyzed with respect to overall, intra- and inter-physician variability, and dependence between variability and origin of the MR images, i.e. the MR sequence used to acquire the data.


RESULTS
The intra-physician variability in different directions was between 1.3 - 1.9 mm and 3 - 4 mm for the prostate and seminal vesicles respectively (1 std). The inter-physician variability for different directions were between 0.7 - 1.7 mm and approximately equal for the prostate and seminal vesicles. Large differences in variability were observed for individual patients, and also for individual imaging sequences used at the different centers. There was however no indication of decreased variability with higher field strength.


CONCLUSION
The overall delineation variability is larger for the seminal vesicles compared to the prostate, due to a larger intra-physician variability. The imaging sequence appears to have a large influence on the variability, even for different variants of the T2-weighted spin-echo based sequences, which were used by all centers in the study.
Structural and optical properties of CuIn1-xGaxSe2 nanoparticles synthesized by solvothermal route

Abstract CuIn 1-x Ga x Se 2 (CIGS) nanoparticles have been successfully fabricated by using a relatively simple and easy handling solvothermal process in the solvent of N, N dimethylformamide (DMF). A probable formation mechanism of chalcopyrite quaternary semiconductor nanoparticles is proposed. Structural, morphological and optical properties of prepared nanoparticles CIGS (x = 0, 0.3, 0.6, 0.8 and 1) were analyzed. The synthesized product is of ordered chalcopyrite structure, with the particle size in the range of 15–25 nm Cu 2 Se secondary phases was detected by XRD for the sample with x = 1, which is also affirmed by Raman spectra. Cathodoluminescence measurements allowed us to observe a high emission which can be attributed to a band to band transition, and the possible energy gap was discussed. The absorption spectra showed strong absorption in the entire visible light to near-infrared region. All results suggested that the as-prepared CIGS nanoparticles were good light absorber layer material for thin film solar cell applications.
Information-Based Objective Functions for Active Data Selection

Learning can be made more efficient if we can actively select particularly salient data points. Within a Bayesian learning framework, objective functions are discussed that measure the expected informativeness of candidate measurements. Three alternative specifications of what we want to gain information about lead to three different criteria for data selection. All these criteria depend on the assumption that the hypothesis space is correct, which may prove to be their main weakness.
Evaluating Education Payoff in Russia

Degrees in Technology, Law or Economics are Better Rewarded by the Market (from ?Beyond Transition?).
Risk Factors for Bicycle-Motor Vehicle Collisions at Intersections *

In 1992, 722 bicyclists were killed in the United States in collisions with motor vehicles, and an estimated 650,000 people were treated in emergency rooms for bicycle-related injuries. It is remarkable that, for a traffic safety problem of this magnitude, so little research has been conducted to establish the causes of these accidents. Instead, design standards for roadways and bicycle facilities, individual project designs, and laws and policies regarding bicycling are based almost entirely on opinion. The quality of the results is highly variable. This paper reports a study of bicycle -motor vehicle collisions in the city of Palo Alto, California. The study compares personal characteristics and bicycling behavior-age, sex, direction of travel (with or against traffic flow), and position on the road (roadway or sidewalk) of bicyclists involved in accidents with similar data for the general population of bicyclists observed along the same streets. This comparison enables us to identify factors that are correlated with increased risk of bicycle -motor vehicle collisions, and to suggest engineering practices that reduce this risk.
Impact of informational factors on online recommendation credibility: The moderating role of source credibility

a r t i c l e i n f o This study investigates the moderating effect of recommendation source credibility on the causal relationships between informational factors and recommendation credibility, as well as its moderating effect on the causal relationship between recommendation credibility and recommendation adoption. Using data from 199 responses from a leading online consumer discussion forum in China, we find that recommendation source credibility significantly moderates two informational factors' effects on readers' perception of recommendation credibility, each in a different direction. Further, we find that source credibility negatively moderates the effect of recommendation credibility on recommendation adoption. Traditional word-of-mouth (WOM) has been shown to play an important role on consumers' purchase decisions (e.g., [2]). With the popularization of the Internet, more and more consumers have shared their past consuming experiences (i.e., online consumer recommendation) online, and researchers often refer to this online WOM as electronic word-of-mouth (eWOM). Given the distinct characteristics of Internet communication (e.g., available to individuals without the limitation of time and location, directed to multiple individuals simultaneously), eWOM has conquered known limitations of traditional WOM. In general, eWOM has global reach and influence. In China, many online consumer discussion forums support eWOM, and much previous research [3,7,12,13,21] demonstrates that because eWOM provides indirect purchasing knowledge to readers, the recommendations on these forums can significantly affect their attitudes towards various kinds of consuming targets (e.g., stores, products and services). Various prior studies have postulated large numbers of antecedent factors which can affect information readers' cognition towards the recommendations, and many of them stem from elaboration likelihood model (ELM) (e. that there are two distinct routes that can affect information readers' attitude toward presented information: (1) the central route that considers the attitude formation (or change) as the result of the receivers' diligent consideration of the content of the information (informational factors); and (2) the peripheral route that requires less cognitive work attuned to simple cues in the information to influence attitude (information-irrelevant factors). ELM suggests two factors, named information readers' motivation and ability, can be the significant moderators to shift the effects of central and peripheral factors on readers' perception of information credibility. Other researchers [24,27] posit that the peripheral factor – source credibility – may also have a moderating rather than a direct effect on the causal relationship between the informational factors and the information credibility; this view is consistent with the attribution inference …
The Level of Faculty Members ' Spiritual Leadership ( SL ) Qualities Display According To Students in Faculty of Education

Leadership is a process directing to a target of which followers, the participators are shared. For this reason leadership has an important effect on succeeding organizational targets. More importance is given to the leadership studies in order to increase organizational success each day. One of the leadership researches that attracts attention recently is spiritual leadership. Spiritual leadership (SL) is important for imposing ideal to the followers and giving meaning to the works they do. Focusing on SL that has recently taken its place in leadership literature, this study looks into what extend faculty members teaching at Faculty of Education display SL qualities. The study is in descriptive scanning model. 1819 students studying at Kocaeli University Faculty of Education in 2009-2010 academic year constitute the universe of the study. Observing leadership qualities takes long time. Therefore, the sample of the study is determined by deliberate sampling method and includes 432 students studying at the last year of the faculty. Data regarding faculty members' SL qualities were collected using a questionnaire adapted from Fry's (2003) 'Spiritual Leadership Scale'. Consequently, university students think that academic stuff shows the features of SL and its sub dimensions in a medium level. According to students, academicians show attitudes related to altruistic love rather than faith and vision. It is found that faculty members couldn't display leadership qualities enough according to the students at the end of the study. © 2011 Published by Elsevier Ltd.
The naked and the dead: the ABCs of gymnosperm reproduction and the origin of the angiosperm flower.

20 years after establishment of the ABC model many of the molecular mechanisms underlying development of the angiosperm flower are relatively well understood. Central players in the gene regulatory network controlling flower development are SQUA-like, DEF/GLO-like, AG-like and AGL6/SEP1-like MIKC-type MADS-domain transcription factors. These provide class A, class B, class C and the more recently defined class E floral homeotic functions, respectively. There is evidence that the floral homeotic proteins recognize the DNA of target genes in an organ-specific way as multimeric protein complexes, thus constituting 'floral quartets'. In contrast to the detailed insights into flower development, how the flower originated during evolution has remained enigmatic. However, while orthologues of all classes of floral homeotic genes appear to be absent from all non-seed plants, DEF/GLO-like, AG-like, and AGL6-like genes have been found in diverse extant gymnosperms, the closest relatives of the angiosperms. While SQUA-like and SEP1-like MADS-box genes appear to be absent from extant gymnosperms, reconstruction of MADS-box gene phylogeny surprisingly suggests that the most recent common ancestor of gymnosperms and angiosperms possessed representatives of both genes, but that these have been lost in the lineage that led to extant gymnosperms. Expression studies and genetic complementation experiments indicate that both angiosperm and gymnosperm AG-like and DEF/GLO-like genes have conserved functions in the specification of reproductive organs and in distinguishing male from female organs, respectively. Based on these findings novel models about the molecular basis of flower origin, involving changes in the expression patterns of DEF/GLO-like or AGL6/SEP1/SQUA-like genes in reproductive structures, were developed. While in angiosperms SEP1-like proteins play an important role in floral quartet formation, preliminary evidence suggests that gymnosperm DEF/GLO-like and AG-like proteins alone can already form floral quartet-like complexes, further corroborating the view that the formation of floral quartet-like complexes predated flower origin during evolution.
Implementation and analysis of three steganographic approaches

Due to increasing the technologies security systems are very popular in many areas. The security of information can be achieved by using encryption and steganography. In cryptography, encrypted data is transmitted after transforming the other form instead of the original data. Contrast cryptography, information hiding process can be extended for protecting from the interesting of any attacker. This paper proposes the enhance security system by combining these two techniques. In this system, the encrypted message is embedded in a BMP image file. In proposed system, three LSB steganographic techniques have been implemented and analyzed. This proposed system intends for data confidentiality, data authentication and data integrity. This system not only enhances the security of data but also becomes more powerful mechanism. This system intends to support effective ways for protecting data. The primary goal of our system is to enhance the security of data and then to compare three steganographic techniques. Then we will use the optimized method for embedding. In this paper, we just present three steganographic approaches. In this system, data is encrypted with RC4 encryption algorithm and then embedded the encrypted text in the BMP image file using three steganogrpaphic methods.
Transcatheter closure of interatrial communications for secondary prevention of paradoxical embolism: single-center experience.

BACKGROUND
Patients with a patent foramen ovale (PFO) after cerebral, coronary, or systemic embolic events of presumed paradoxical origin are at risk for recurrent thromboembolism. We report our single-center experience of interventional closure of interatrial communications for secondary prevention of presumed paradoxical embolism. Methods and Results- Since 1997, percutaneous closure of interatrial communications was performed at our institution in 66 patients (mean age 47.8+/-12.7 years; 31 males) with a PFO or an atrial septal defect and at least 1 documented presumed paradoxical thromboembolic event. Fifty-eight patients had cerebral embolism, 10 had coronary embolism, and 3 had peripheral embolism. Several patients experienced multilocal arterial embolism. Fifty-four patients had a PFO, 33 of them with an atrial septal aneurysm, and 12 had an atrial septal defect. The implantation procedure was successful and without complication in all patients. After 3 months, only 2 patients showed a residual shunt, which disappeared in both cases after 12 months. In 112.2 patient-years of follow-up (range, 5 weeks to 3.5 years), we have not seen any recurrent thromboembolic event.


CONCLUSIONS
Interventional closure of interatrial communications is a safe and effective therapeutic option for the secondary prevention of presumed paradoxical embolism. To further evaluate this strategy, randomized trials comparing interventional closure with anticoagulation have been initiated by us and others.