LLukas22/scidocs huggingface dataset:
Evolution of Navajo eclogites and hydration of the mantle wedge below the Colorado Plateau, southwestern United States: EVOLUTION OF NAVAJO ECLOGITES

[1] Eclogite and pyroxenite xenoliths from ultramafic diatremes of the Navajo province on the Colorado Plateau have been analyzed to investigate hydration of continental mantle and effects of low-angle subduction on the mantle wedge. Xenoliths have been characterized by petrographic and electron probe analysis and by Sm-Nd, Rb-Sr, K-Ar, and O isotopic analysis of mineral separates from one eclogite and by U-Pb isotopic analysis of zircons from three samples. K-Ar analysis of phengite establishes eruption of a Garnet Ridge, Arizona, diatreme at 30 Ma. Sm-Nd and Rb-Sr analyses of clinopyroxene and garnet from that eclogite document recrystallization shortly preceding eruption. Three zircon fractions have been analyzed from that eclogite and from two others representing the nearby Moses Rock and Mule Ear diatremes. Seven of nine small multigrain fractions scatter about a poorly fit discordia between ca. 35 Ma and 1515 Ma (fractions range from overlapping concordia at the lower intercept to a 207Pb/206Pb age of ca. 1220 Ma). The discordant fractions establish a mid-Proterozoic zircon component in each eclogite, inconsistent with an origin from basalt of the Farallon plate. The pressure recorded by one of these eclogites (3.3 GPa) exceeds that of an eclogite previously attributed to the Farallon plate. Nonetheless, each of the eclogites contains a fraction of nearly concordant zircons with ages in the range 35 to 41 Ma, and one rock also contains a fraction that is nearly concordant at 70 Ma. These concordant ages are interpreted to record episodic zircon growth during recrystallization of Proterozoic mantle. The concordant zircon ages are consistent with published data that establish recrystallization of Navajo eclogites from 81 to 33 Ma, a time interval similar to that of the Laramide orogeny. The eclogite-facies recrystallization and growth of new zircon are attributed to the catalytic effects of water introduced into the mantle from the Farallon slab. Water penetrated fracture zones extending for at least tens of kilometers into the mantle wedge above the Farallon slab during low-angle subduction. Magmatism in the San Juan volcanic field to the northeast of the diatremes may be related to similar hydration.
A Zika Vaccine Targeting NS1 Protein Protects Immunocompetent Adult Mice in a Lethal Challenge Model

Zika virus (ZIKV) is a mosquito-borne flavivirus that has rapidly extended its geographic range around the world. Its association with abnormal fetal brain development, sexual transmission, and lack of a preventive vaccine have constituted a global health concern. Designing a safe and effective vaccine requires significant caution due to overlapping geographical distribution of ZIKV with dengue virus (DENV) and other flaviviruses, possibly resulting in more severe disease manifestations in flavivirus immune vaccinees such as Antibody-Dependent Enhancement (ADE, a phenomenon involved in pathogenesis of DENV, and a risk associated with ZIKV vaccines using the envelope proteins as immunogens). Here, we describe the development of an alternative vaccine strategy encompassing the expression of ZIKV non-structural-1 (NS1) protein from a clinically proven safe, Modified Vaccinia Ankara (MVA) vector, thus averting the potential risk of ADE associated with structural protein-based ZIKV vaccines. A single intramuscular immunization of immunocompetent mice with the MVA-ZIKV-NS1 vaccine candidate provided robust humoral and cellular responses, and afforded 100% protection against a lethal intracerebral dose of ZIKV (strain MR766). This is the first report of (i) a ZIKV vaccine based on the NS1 protein and (ii) single dose protection against ZIKV using an immunocompetent lethal mouse challenge model.
Identification of penumbra and infarct in acute ischemic stroke using computed tomography perfusion-derived blood flow and blood volume measurements.

BACKGROUND AND PURPOSE
We investigated whether computed tomography (CT) perfusion-derived cerebral blood flow (CBF) and cerebral blood volume (CBV) could be used to differentiate between penumbra and infarcted gray matter in a limited, exploratory sample of acute stroke patients.


METHODS
Thirty patients underwent a noncontrast CT (NCCT), CT angiography (CTA), and CT perfusion (CTP) scan within 7 hours of stroke onset, NCCT and CTA at 24 hours, and NCCT at 5 to 7 days. Twenty-five patients met the criteria for inclusion and were subsequently divided into 2 groups: those with recanalization at 24 hours (n=16) and those without (n=9). Penumbra was operationally defined as tissue with an admission CBF <25 mL x 100 g(-1) x min(-1) that was not infarcted on the 5- to 7-day NCCT. Logistic regression was applied to differentiate between infarct and penumbra data points.


RESULTS
For recanalized patients, CBF was significantly lower (P<0.05) for infarct (13.3+/-3.75 mL x 100 g(-1) x min(-1)) than penumbra (25.0+/-3.82 mL x 100 g(-1) x min(-1)). CBV in the penumbra (2.15+/-0.43 mL x 100 g(-1)) was significantly higher than contralateral (1.78+/-0.30 mL x 100 g(-1)) and infarcted tissue (1.12+/-0.37 mL x 100 g(-1)). Logistic regression using an interaction term (CBFxCBV) resulted in sensitivity, specificity, and accuracy of 97.0%, 97.2%, and 97.1%, respectively. The interaction term resulted in a significantly better (P<0.05) fit than CBF or CBV alone, suggesting that the CBV threshold for infarction varies with CBF. For patients without recanalization, CBF and CBV for infarcted regions were 15.1+/-5.67 mL x 100 g(-1) x min(-1) and 1.17+/-0.41 mL x 100 g(-1), respectively.


CONCLUSIONS
We have shown in a limited sample of patients that CBF and CBV obtained from CTP can be sensitive and specific for infarction and should be investigated further in a prospective trial to assess their utility for differentiating between infarct and penumbra.
Evaluation of segmentation methods on head and neck CT: Auto-segmentation challenge 2015.

PURPOSE
Automated delineation of structures and organs is a key step in medical imaging. However, due to the large number and diversity of structures and the large variety of segmentation algorithms, a consensus is lacking as to which automated segmentation method works best for certain applications. Segmentation challenges are a good approach for unbiased evaluation and comparison of segmentation algorithms.


METHODS
In this work, we describe and present the results of the Head and Neck Auto-Segmentation Challenge 2015, a satellite event at the Medical Image Computing and Computer Assisted Interventions (MICCAI) 2015 conference. Six teams participated in a challenge to segment nine structures in the head and neck region of CT images: brainstem, mandible, chiasm, bilateral optic nerves, bilateral parotid glands, and bilateral submandibular glands.


RESULTS
This paper presents the quantitative results of this challenge using multiple established error metrics and a well-defined ranking system. The strengths and weaknesses of the different auto-segmentation approaches are analyzed and discussed.


CONCLUSIONS
The Head and Neck Auto-Segmentation Challenge 2015 was a good opportunity to assess the current state-of-the-art in segmentation of organs at risk for radiotherapy treatment. Participating teams had the possibility to compare their approaches to other methods under unbiased and standardized circumstances. The results demonstrate a clear tendency toward more general purpose and fewer structure-specific segmentation algorithms.
A reduced model for interactive hairs

Realistic hair animation is a crucial component in depicting virtual characters in interactive applications. While much progress has been made in high-quality hair simulation, the overwhelming computation cost hinders similar fidelity in realtime simulations. To bridge this gap, we propose a data-driven solution. Building upon precomputed simulation data, our approach constructs a reduced model to optimally represent hair motion characteristics with a small number of guide hairs and the corresponding interpolation relationships. At runtime, utilizing such a reduced model, we only simulate guide hairs that capture the general hair motion and interpolate all rest strands. We further propose a hair correction method that corrects the resulting hair motion with a position-based model to resolve hair collisions and thus captures motion details. Our hair simulation method enables a simulation of a full head of hairs with over 150K strands in realtime. We demonstrate the efficacy and robustness of our method with various hairstyles and driven motions (e.g., head movement and wind force), and compared against full simulation results that does not appear in the training data.
Fish oil for the reduction of atrial fibrillation recurrence, inflammation, and oxidative stress.

BACKGROUND
Recent trials of fish oil for the prevention of atrial fibrillation (AF) recurrence have provided mixed results. Notable uncertainties in the existing evidence base include the roles of high-dose fish oil, inflammation, and oxidative stress in patients with paroxysmal or persistent AF not receiving conventional antiarrhythmic (AA) therapy.


OBJECTIVES
The aim of this study was to evaluate the influence of high-dose fish oil on AF recurrence, inflammation, and oxidative stress parameters.


METHODS
We performed a double-blind, randomized, placebo-controlled, parallel-arm study in 337 patients with symptomatic paroxysmal or persistent AF within 6 months of enrollment. Patients were randomized to fish oil (4 g/day) or placebo and followed, on average, for 271 ± 129 days.


RESULTS
The primary endpoint was time to first symptomatic or asymptomatic AF recurrence lasting >30 s. Secondary endpoints were high-sensitivity C-reactive protein (hs-CRP) and myeloperoxidase (MPO). The primary endpoint occurred in 64.1% of patients in the fish oil arm and 63.2% of patients in the placebo arm (hazard ratio: 1.10; 95% confidence interval: 0.84 to 1.45; p = 0.48). hs-CRP and MPO were within normal limits at baseline and decreased to a similar degree at 6 months (Δhs-CRP, 11% vs. -11%; ΔMPO, -5% vs. -9% for fish oil vs. placebo, respectively; p value for interaction = NS).


CONCLUSIONS
High-dose fish oil does not reduce AF recurrence in patients with a history of AF not receiving conventional AA therapy. Furthermore, fish oil does not reduce inflammation or oxidative stress markers in this population, which may explain its lack of efficacy. (Multi-center Study to Evaluate the Effect of N-3 Fatty Acids [OMEGA-3] on Arrhythmia Recurrence in Atrial Fibrillation [AFFORD]; NCT01235130).
Detection and Classification of Hyper-Spectral Edges

Intensity-based edge detectors cannot distinguish whether an edge is caused by material changes, shadows, surface orientation changes or by highlights. Therefore, our aim is to classify the physical cause of an edge using hyperspectra obtained by a spectrograph. Methods are presented to detect edges in hyperspectral images. In theory, the effect of varying imaging conditions is analyzed for ”raw” hyper-spectra, for normalized hyper-spectra, and for hue computed from hyper-spectra. From this analysis, an edge classifier is derived which distinguishes hyper-spectral edges into the following types: (1) a shadow or geometry edge, (2) a highlight edge, (3) a material edge.
More than bin packing: Dynamic resource allocation strategies in cloud data centers

Resource allocation strategies in virtualized data centers have received considerable attention recently as they can have substantial impact on the energy efficiency of a data center. This led to new decision and control strategies with significant managerial impact for IT service providers. We focus on dynamic environments where virtual machines need been analyzed and used to place virtual machines upon arrival. However, these placement heuristics can lead to suboptimal server utilization, because they cannot consider virtual machines, which arrive in the future. We ran extensive lab experiments and simulations with different controllers and different workloads to understand which control strategies achieve high levels of energy efficiency in different workload environments. We found that combinations of placement controllers and periodic reallocations achieve the highest energy efficiency subject to predefined service levels. While the type of placement heuristic had little impact on the average server demand, the type of virtual machine resource demand estimator used for the placement decisions had a significant impact on the overall energy efficiency. & 2015 Elsevier Ltd. All rights reserved.
Consumer trust in B 2 C e-Commerce and the importance of social presence : experiments in e-Products and e-Services

Reducing social uncertainty—understanding, predicting, and controlling the behavior of other people—is a central motivating force of human behavior. When rules and customs are not su4cient, people rely on trust and familiarity as primary mechanisms to reduce social uncertainty. The relative paucity of regulations and customs on the Internet makes consumer familiarity and trust especially important in the case of e-Commerce. Yet the lack of an interpersonal exchange and the one-time nature of the typical business transaction on the Internet make this kind of consumer trust unique, because trust relates to other people and is nourished through interactions with them. This study validates a four-dimensional scale of trust in the context of e-Products and revalidates it in the context of e-Services. The study then shows the in:uence of social presence on these dimensions of this trust, especially benevolence, and its ultimate contribution to online purchase intentions. ? 2004 Elsevier Ltd. All rights reserved.
Characteristics and anticorrosion performance of Fe-doped TiO2 films by liquid phase deposition method

Abstract Fe-doped TiO 2 thin films were fabricated by liquid phase deposition (LPD) method, using Fe(III) nitrate as both Fe element source and fluoride scavenger instead of commonly-used boric acid (H 3 BO 3 ). Scanning electron microscopy (SEM), X-ray diffraction (XRD), and UV–vis spectrum were employed to examine the effects of Fe element on morphology, structure and optical characteristics of TiO 2 films. The as-prepared films were served as photoanode applied to photogenerated cathodic protection of SUS304 stainless steel (304SS). It was observed that the photoelectrochemical properties of the as-prepared films were enhanced with the addition of Fe element compared to the undoped TiO 2 film. The highest photoactivity was achieved for Ti13Fe (Fe/Ti = 3 molar ratio) film prepared in precursor bath containing 0.02 M TiF 4  + 0.06 M Fe(NO 3 ) 3 under white-light illumination. The effective anticorrosion behaviors can be attributed to the Fe element incorporation which decreases the probability of photogenerated charge-carrier recombination and extends the light response range of Fe-doped TiO 2 films appeared to visible-light region.
A critical appraisal of logistic regression-based nomograms, artificial neural networks, classification and regression-tree models, look-up tables and risk-group stratification models for prostate cancer.

OBJECTIVE
To evaluate several methods of predicting prostate cancer-related outcomes, i.e. nomograms, look-up tables, artificial neural networks (ANN), classification and regression tree (CART) analyses and risk-group stratification (RGS) models, all of which represent valid alternatives.


METHODS
We present four direct comparisons, where a nomogram was compared to either an ANN, a look-up table, a CART model or a RGS model. In all comparisons we assessed the predictive accuracy and performance characteristics of both models.


RESULTS
Nomograms have several advantages over ANN, look-up tables, CART and RGS models, the most fundamental being a higher predictive accuracy and better performance characteristics.


CONCLUSION
These results suggest that nomograms are more accurate and have better performance characteristics than their alternatives. However, ANN, look-up tables, CART analyses and RGS models all rely on methodologically sound and valid alternatives, which should not be abandoned.
A new NSF thrust: computer impact on society

The recently formed (Nov. 9, 1972) Computer Impact on Society Section in NSF's Office of Computing Activities reflected a growing need to understand the wide and deep impact which computers and associated information technology are having on our social organizations and way of life. The program has two principal thrusts, computer impact on organizations and computer impact on the individual, to be implemented via studies and demonstrations. As experience is gained and the program matures, research projects of considerable scope and import may be reasonably expected which will develop ways computer science and technology can be creatively applied to meeting individual and social needs.
Short-Term Load Forecasting Methods: An Evaluation Based on European Data

This paper uses intraday electricity demand data from ten European countries as the basis of an empirical comparison of univariate methods for prediction up to a day-ahead. A notable feature of the time series is the presence of both an in-traweek and an intraday seasonal cycle. The forecasting methods considered in the study include: ARIMA modeling, periodic AR modeling, an extension for double seasonality of Holt-Winters exponential smoothing, a recently proposed alternative exponential smoothing formulation, and a method based on the principal component analysis (PCA) of the daily demand profiles. Our results show a similar ranking of methods across the 10 load series. The results were disappointing for the new alternative exponential smoothing method and for the periodic AR model. The ARIMA and PCA methods performed well, but the method that consistently performed the best was the double seasonal Holt-Winters exponential smoothing method.
The impact of online store environment cues on purchase intention: Trust and perceived risk as a mediator

Purpose – The purpose of this paper is to investige whether online environment cues (web site quality and web site brand) affect customer purchase intention towards an online retailer and whether this impact is mediated by customer trust and perceived risk. The study also aimed to assess the degree of reciprocity between consumers’ trust and perceived risk in the context of an online shopping environment. Design/methodology/approach – The study proposed a research framework for testing the relationships among the constructs based on the stimulus-organism-response framework. In addition, this study developed a non-recursive model. After the validation of measurement scales, empirical analyses were performed using structural equation modelling. Findings – The findings confirm that web site quality and web site brand affect consumers’ trust and perceived risk, and in turn, consumer purchase intention. Notably, this study finds that the web site brand is a more important cue than web site quality in influencing customers’ purchase intention. Furthermore, the study reveals that the relationship between trust and perceived risk is reciprocal. Research limitations/implications – This study adopted four dimensions – technical adequacy, content quality, specific content and appearance – to measure web site quality. However, there are still many competing concepts regarding the measurement of web site quality. Further studies using other dimensional measures may be needed to verify the research model. Practical implications – Online retailers should focus their marketing strategies more on establishing the brand of the web site rather than improving the functionality of the web site. Originality/value – This study proposed a non-recursive model for empirically analysing the link between web site quality, web site brand, trust, perceived risk and purchase intention towards the online retailer.
A New Way for Antihelixplasty in Prominent Ear Surgery: Modified Postauricular Fascial Flap.

BACKGROUND
Otoplasty procedures aim to reduce the concha-mastoid angle and recreate the antihelical fold. Here, we explained the modified postauricular fascial flap, described as a new way for recreating the antihelical fold, and reported the results of patients on whom this flap was used.


MATERIALS AND METHODS
The defined technique was used on 24 patients (10 females and 14 males; age, 6-27 years; mean, 16.7 years) between June 2009 and July 2012, a total of 48 procedures in total (bilateral). Follow-up ranged from 1 to 3 years (mean, 1.5 years). At the preoperative and postoperative time points (1 and 12 months after surgery), all patients were measured for upper and middle helix-head distance and were photographed. The records were analyzed statistically using t test and analysis of variance.


RESULTS
The procedure resulted in ears that were natural in appearance without any significant visible evidence of surgery. The operations resulted in no complications except 1 patient who developed a small skin ulcer on the left ear because of band pressure. When we compared the preoperative and postoperative upper and middle helix-head distance, there was a high significance statistically.


CONCLUSIONS
To introduce modified postauricular fascial flap, we used a simple and safe procedure to recreate an antihelical fold. This procedure led to several benefits, including a natural-in-appearance antihelical fold, prevention of suture extrusion and granuloma, as well as minimized risk for recurrence due to neochondrogenesis. This method may be used as a standard procedure for treating prominent ears surgically.
The Burden of Large and Small Duct Primary Sclerosing Cholangitis in Adults and Children: A Population-Based Analysis

OBJECTIVES:The epidemiology of primary sclerosing cholangitis (PSC) has been incompletely assessed by population-based studies. We therefore conducted a population-based study to determine: (a) incidence rates of large and small duct PSC in adults and children, (b) the risk of inflammatory bowel disease on developing PSC, and (c) patterns of clinical presentation with the advent of magnetic resonance cholangiopancreatography (MRCP).METHODS:All residents of the Calgary Health Region diagnosed with PSC between 2000 and 2005 were identified by medical records, endoscopic, diagnostic imaging, and pathology databases. Demographic and clinical information were obtained. Incidence rates were determined and risks associated with PSC were reported as rate ratios (RR) with 95% confidence intervals (CI).RESULTS:Forty-nine PSC patients were identified for an age- and gender-adjusted annual incidence rate of 0.92 cases per 100,000 person-years. The incidence of small duct PSC was 0.15/100,000. In children the incidence rate was 0.23/100,000 compared with 1.11/100,000 in adults. PSC risk was similar in Crohn's disease (CD; RR 220.0, 95% CI 132.4–343.7) and ulcerative colitis (UC; RR 212.4, 95% CI 116.1–356.5). Autoimmune hepatitis overlap was noted in 10% of cases. MRCP diagnosed large duct PSC in one-third of cases. Delay in diagnosis was common (median 8.4 months). A minority had complications at diagnosis: cholangitis (6.1%), pancreatitis (4.1%), and cirrhosis (4.1%).CONCLUSIONS:Pediatric cases and small duct PSC are less common than adult large duct PSC. Surprisingly, the risk of developing PSC in UC and CD was similar. Autoimmune hepatitis overlap was noted in a significant minority of cases.