LLukas22/scidocs huggingface dataset:
Skiing and snowboarding injuries.

OBJECTIVE
To critically examine the literature on skiing and snowboarding injuries in children and adolescents.


DATA SOURCES
Searched English language articles from: Medline, SPORTDiscus, Cumulative Index to Nursing and Allied Health Literature, Current Contents, and HealthSTAR. The table of contents for Ski Trauma and Skiing Safety Series published by the American Society for Testing and Materials were also examined. MeSH headings included: Sports, Athletic Injuries, and Accidents. Keywords used within these headings were Skiing and/or Snowboarding with focus on children, adolescents, youth, students, or age group-related comparisons.


MAIN RESULTS
The patterns and rates of injury differed markedly by activity and study design. Most studies were case-series investigations providing little useful information on risk factors. Intrinsic risk factors included: lower ability, younger age, past injury, and female sex. Extrinsic risk factors were improper binding adjustment, no helmet, certain slope characteristics, and no wrist guards. The literature on the effect of activity, equipment ownership and lessons on injury risk was equivocal.


CONCLUSIONS
Suggestions for injury prevention include the use of helmets and wrist guards, participation on appropriate runs for ability level, proper fit and adjustment of bindings and other equipment, and taking lessons with the goal of increasing ability and learning hill etiquette. Many areas requiring further research are identified and discussed. New methodological approaches hold promise in advancing the field of ski and snowboard injury research.
Is There a Disability Gap in Employment Rates in Developing Countries

This paper examines differences in employment rates between persons with and without disabilities in 15 developing countries using the World Health Survey. We find that people with disabilities have lower employment rates than persons without disabilities in nine countries. Across countries, disability gaps in employment rates are more often found for men than women. The largest disability gap in employment rates is found for persons with multiple disabilities. For countries with a disability gap, results from a logistic decomposition suggest that observable characteristics of persons with/without disabilities do not explain most of the gap.
Evaluation of 0.6% sodium alginate as a submucosal injection material in endoscopic submucosal dissection for early gastric cancer.

BACKGROUND AND AIM
We have focused on sodium alginate (SA) solution as a potential submucosal injection material for endoscopic submucosal dissection (ESD). A previous SA solution had high viscosity and problems such as difficult handling. After its properties were adjusted, SA solution was examined in vitro and its clinical safety was evaluated.


METHODS
With 0.4% sodium hyaluronate (SH) solution as a control, catheter injectability and mucosa-elevating capacity of 0.3-0.8% SA solutions were evaluated. Next, 0.6% SA solution was used for ESD in 10 patients with early gastric cancer in a prospective clinical study.


RESULTS
Compared with 0.4% SH solution, 0.6% SA solution exhibited no significant difference in catheter injectability but significant superiority in mucosa-elevating capacity. In the clinical study, no adverse events were observed in any patient.


CONCLUSION
The safety of 0.6% SA solution as a submucosal injection material was confirmed and it is suggested that its efficacy should be investigated in a larger number of cases.
Association Between a Social-Business Eating Pattern and Early Asymptomatic Atherosclerosis.

BACKGROUND
The importance of a healthy diet in relation to cardiovascular health promotion is widely recognized. Identifying specific dietary patterns related to early atherosclerosis would contribute greatly to inform effective primary prevention strategies.


OBJECTIVES
This study sought to quantify the association between specific dietary patterns and presence and extent of subclinical atherosclerosis in a population of asymptomatic middle-aged adults.


METHODS
The PESA (Progression of Early Subclinical Atherosclerosis) study enrolled 4,082 asymptomatic participants 40 to 54 years of age (mean age 45.8 years; 63% male) to evaluate the presence of subclinical atherosclerosis in multiple vascular territories. A fundamental objective of this cohort study was to evaluate the life-style-related determinants, including diet, on atherosclerosis onset and development. We conducted a cross-sectional analysis of baseline data, including detailed information on dietary habits obtained as part of the overall life-style and risk factor assessment, as well as a complete vascular imaging study that was performed blinded to the clinical information.


RESULTS
Most PESA participants follow a Mediterranean (40% of participants) or a Western (41%) dietary pattern. A new pattern, identified among 19% of participants, was labeled as a social-business eating pattern, characterized by a high consumption of red meat, pre-made foods, snacks, alcohol, and sugar-sweetened beverages and frequent eating-out behavior. Participants following this pattern presented a significantly worse cardiovascular risk profile and, after adjustment for risk factors, increased odds of presenting subclinical atherosclerosis (odds ratio: 1.31; 95% confidence interval: 1.06 to 1.63) compared with participants following a Mediterranean diet.


CONCLUSIONS
A new social-business eating pattern, characterized by high consumption of red and processed meat, alcohol, and sugar-sweetened beverages, and by frequent snacking and eating out as part of an overall unhealthy life-style, is associated with an increased prevalence, burden, and multisite presence of subclinical atherosclerosis. (Progression of Early Subclinical Atherosclerosis [PESA]; NCT01410318).
Compact High-Performance Reflector-Antenna Feeds and Feed Networks for Space Applications [Antenna Applications]

Reflector antennas are widely used on satellites to communicate with ground stations. They simultaneously transmit and receive RF signals using separate downlink and uplink frequency bands. These antennas require compact and high-performance feed assemblies with small size, low mass, low passive intermodulation (PIM) products [1], low insertion loss, high power handling, and low cross-polar levels. The feeds must also be insensitive to large thermal variations, and must survive the launch environment. In order to achieve these desirable features without prototyping and/or bench tuning, Custom Microwave Inc. (CMI) has combined integrated RF design, precision CAD, and a precision manufacturing technique known as electroforming to closely integrate the various components of a feed or feed network, thereby achieving small size while maintaining high RF performance [2]. In addition to close integration, electroforming eliminates split joints and minimizes flanges by allowing several components to be realized in a single piece, making it the ideal manufacturing technique for ultra-low passive-intermodulation applications. This paper describes the use of precision design CAD tools along with electroforming to realize high-performance feed assemblies for various communication frequency bands for fixed satellite, broadcast satellite, and broadband satellite services.
Y chromosomal DNA variation in East Asian populations and its potential for inferring the peopling of Korea

AbstractWe have examined variations of five polymorphic loci (DYS287, DXYS5Y, SRY465, DYS19, and DXYS156Y) on the Y chromosome in samples from a total of 1260 males in eight ethnic groups of East Asia. We found four unique haplotypes constructed from three biallelic markers in these samples of East Asians. The Japanese population was characterized by a relatively high frequency of either the haplotype I-2b (−/Y2/T) or II-1 (+/Y1/C). These dual patterns of the distribution of Y chromosomes (I-2b/II-1) were also found in Korea, although they were present at relatively low frequencies. The haplotype II-1 was present in Northeast Asian populations (Chinese, Japanese, Koreans, and Mongolians) only, except for one male from the Thai population among the Southeast Asian populations (Indonesians, Philippines, Thais, and Vietnamese). The Japanese were revealed to have the highest frequency of this haplotype (27.5%), followed by Koreans (2.9%), Mongolians (2.6%), and mainland Chinese (2.2%). In contrast, the frequency of the haplotype I-2b was found to be 17.1% in the Japanese, 9.5% in Indonesian, 6.3% in Korean, 3.8% in Vietnamese, and 2.7% in Thai samples. These findings suggested that the chromosomes of haplotype I-2b were likely derived from certain areas of Northeast Asia, the region closest to Southeast Asia. Phylogenetic analysis using the neighbor-joining tree also reflected a general distinction between Southeast and Northeast Asian populations. The phylogeny revealed a closer genetic relationship between Japanese and Koreans than to the other surveyed Asian populations. Based on the result of the dual patterns of the haplotype distribution, it is more likely that the population structure of Koreans may not have evolved from a single ancient population derived from Northeast Asians, but through dual infusions of Y chromosomes entering Korea from two different waves of East Asians.
Usefulness of facial nerve monitoring for confirmation of greater superficial petrosal nerve in anterior transpetrosal approach

The greater superficial petrosal nerve (GSPN) is especially important in anterior transpetrosal approach (ATPA) as the most reliable superficial landmark of Kawase’s triangle. The GSPN can be considered as the superficial lateral border of anterior petrosectomy on the middle fossa to avoid internal carotid artery (ICA) injury. Although experienced operators can find the GSPN, its confirmation is not always easy to achieve. We introduce our recent GSPN confirmation methods using facial nerve monitoring. In 10 recent cases, antidromic GSPN stimulation and free-running facial muscle electromyography (EMG) monitoring were performed. Facial nerve evoked-EMG by antidromic GSPN stimulation confirmed the location of the GSPN course with precision in all cases. Free-running facial muscle EMG informed the mechanical stress of facial nerves through the GSPN. There was no postoperative facial palsy or dry eye in these cases. GSPN confirmation and preservation are not always easy to achieve. These monitoring methods are useful for the confirmation of the GSPN, which is a landmark for safe extradural anterior petrosectomy, and for the preservation of the GSPN itself.
FLEXURAL BEHAVIOUR OF REINFORCED GEOPOLYMER CONCRETE BEAMS PARTIALLY REPLACED WITH RECYCLED COARSE AGGREGATES

Concrete is the most widely used construction material which required large quantities of Portland cement. The production of Ordinary Portland cement causes pollution to the environment, due to the emission of CO2 and also large amount of natural resources is consumed for the cement production. The large global production of flyash and rapid advances in geopolymer technology leads to the alternate material for OPC that is Geopolymer concrete (GPC). Geopolymers are showing great potential and several researchers have critically examined the various aspects of their viability as binder material. In this paper, results of the studies carried out on the behaviour of ambient cured Reinforced GPC (RGPC) flexural member have been presented..A total of 9 beams were tested in flexure, out of which three were conventional concrete mixes and six GPCmixes having varying combinations of flyash, GGBS and recycled coarse aggregates. The reinforcement was designed considering a balanced section and all the specimens were tested under two point loading The studies showed that the load carrying capacity of the RGPC beams was more than that of the corresponding conventional RCC beam and the load carrying capacity of the beams were decreased when replaced with recycled aggregates. The deflection, cracking load, ultimate load and crack width were recorded.
Mark-aided distributed filtering by using neural network for DDoS defense

Currently distributed denial of service (DDoS) attacks have been identified as one of the most serious problems on the Internet. The aim of DDoS attacks is to prevent legitimate users from accessing desired resources, such as network bandwidth. Hence the immediate task of DDoS defense is to provide as much resources as possible to legitimate users when there is an attack. Unfortunately most current defense approaches can not efficiently detect and filter out attack traffic. Our approach is to find the network anomalies by using neural network, deploy the system at distributed routers, identify the attack packets, and then filter them. The marks in the IP header that are generated by a group of IP traceback schemes, deterministic packet marking (DPM)/flexible deterministic packet marking (FDPM), assist this process of identifying attack packets. The experimental results show that this approach can be used to defend against both intensive and subtle DDoS attacks, and can catch DDoS attacks' characteristic of starting from multiple sources to a single victim. According to results, we find the marks in IP headers can enhance the sensitivity and accuracy of detection, thus improve the legitimate traffic throughput and reduce attack traffic throughput. Therefore, it can perform well in filtering DDoS attack traffic precisely and effectively.
Delayed increase in infarct volume after cerebral ischemia: correlations with thrombolytic treatment and clinical outcome.

BACKGROUND AND PURPOSE
Growing experimental evidence indicates that the development of cerebral ischemic damage is slower than previously believed. The aims of this work were (1) to study the evolution of CT hypoattenuation between 24 to 36 hours and 7 days in ischemic stroke patients; (2) to evaluate whether thrombolytic treatment given within 6 hours of stroke affects delayed infarction evolution; and (3) to investigate possible correlations between lesion volume changes over time and clinical outcome.


METHODS
Of 620 patients included in the European Cooperative Acute Stroke Study 1 (ECASS1), we selected 450 patients whose control CT scans at day 1 (CT1) and day 7 (CT7) were available. They had been randomly divided into 2 groups: 206 patients had been treated with rtPA and 244 with placebo. CT1 and CT7 were classified according to the location of the infarct. The volume of CT hypoattenuation was measured using the formula AxBxC/2 for irregular volumes. The 95% confidence interval of inter- and intrarater variability was used to determine whether significant changes in lesion volume had occurred between CT1 and CT7. Clinical severity was evaluated by means of the Scandinavian Stroke Scale (SSS) at entry (SSS0) and at day 30 (SSS30).


RESULTS
Mean lesion volumes were significantly (P<0.0001) higher at day 7 than at day 1 in all the subgroups of patients and particularly in patients with a subcortical lesion. Of the 450 patients studied, 287 (64%) did not show any significant change in lesion volume between CT1 and CT7, 143 (32%) showed a significant increase and the remaining 20 (4%) a significant decrease. No significant correlation was observed between treatment and lesion evolution between CT1 and CT7. Both clinical scores (SSS0 and SSS30) and degree of neurological recovery were significantly (P<0.05) lower in the subgroup of patients with a significant lesion volume increase than in the other 2 groups.


CONCLUSIONS
In approximately two thirds of patients, infarct size is established 24 to 36 hours after stroke onset, whereas in the remaining one third, changes in lesion volume may occur later than the first 24 to 36 hours. Many factors may be responsible for delayed infarct enlargement and for a lower degree of clinical recovery, both of which may occur despite early recombinant tissue plasminogen activator treatment.
Market timing: a test of a charting heuristic

We implement a graphical (or ‘charting’) heuristic, the ‘bull flag’, which accepts a particular pattern of historical prices as a signal for a future market price increase, test it with several years of New York Stock Exchange Composite Index history, and find positive results. The results support the validity of technical analysis for stock market price prediction and fail to confirm the efficient markets hypothesis.  2002 Elsevier Science B.V. All rights reserved.
Reinforcement learning in a nutshell

We provide a concise introduction to basic approaches to reinforcement learning from the machine learning perspective. The focus is on value function and policy gradient methods. Some selected recent trends are highlighted.
Comparison of HRV parameters derived from photoplethysmography and electrocardiography signals

Heart rate variability (HRV) has become a useful tool in analysis of cardiovascular system in both research and clinical fields. HRV has been also used in other applications such as stress level estimation in wearable devices. HRV is normally obtained from ECG as the time interval of two successive R waves. Recently PPG has been proposed as an alternative for ECG in HRV analysis to overcome some difficulties in measurement of ECG. In addition, PPG-HRV is also used in some commercial devices such as modern optical wrist-worn heart rate monitors. However, some researches have shown that PPG is not a surrogate for heart rate variability analysis. In this work, HRV analysis was applied on beat-to-beat intervals obtained from ECG and PPG in 19 healthy male subjects. Some important HRV parameters were calculated from PPG-HRV and ECG-HRV. Maximum of PPG and its second derivative were considered as two methods for obtaining the beat-to-beat signals from PPG and the results were compared with those achieved from ECG-HRV. Our results show that the smallest error happens in SDNN and SD2 with relative error of 2.46% and 2%, respectively. The most affected parameter is pNN50 with relative error of 29.89%. In addition, in our trial, using the maximum of PPG gave better results than its second derivative.
Analysis of postponement strategy for perishable items by EOQ-based models

This paper develops EOQ-based models with perishable items to evaluate the impact of a form postponement strategy on the retailer in a supply chain. We formulate models for a postponement system and an independent system to minimize the total average cost function per unit time for ordering and keeping n perishable end-products. An algorithm is given to derive the optimal solutions of the proposed models. The impact of the deterioration rate on the inventory replenishment policies is studied with the help of theoretical analysis and numerical examples. Our theoretical analysis and computational results show that a postponement strategy for perishable items can give a lower total average cost under certain circumstances.
Community participation for rural health: a review of challenges.

CONTEXT
Internationally, community participation is highlighted in health policy reform as good for rural communities. Implicit in this policy is the message that the complexities of the rural environment are too difficult for easy solutions and that community participation will somehow build resilient, self-determining communities capable of dealing with complex rural access and equity issues and poorer health outcomes. The underpinning proposition is that by giving decision-making powers to community members, health care will be locally responsive, costs will be contained, and health outcomes will improve. What happens in the practice of enacting community participation in health-care decision making is less clear.


OBJECTIVE
Despite the growing body of work that documents different levels and models of community participation, significant gaps that outline the practical challenges inherent in rural community participation remain. In this article, we draw on a body of literature to outline the practical considerations in implementing community participation policy in health settings in rural areas. Through a critical review, we aim to stimulate debate, progress ideas and provide a conceptual representation of the somewhat 'messy' nature of rural community participation at a grass-roots organizational level.


DISCUSSION AND CONCLUSION
Based on our analysis of the current literature, we provide a summary of challenges and practical strategies that might mitigate some of these challenges. Our review highlights that despite policymakers suggesting that community participation is good for rural communities, policy enactment must move beyond mandated tokenism for there to be a recognition that meaningful participation is neither easy nor linear.
A randomized, placebo- and active-controlled, parallel-group, multicentre, investigator-blinded study of four treatment regimens of posaconazole in adults with toenail onychomycosis.

BACKGROUND
Onychomycosis accounts for up to 50% of all onychopathies.


OBJECTIVES
To evaluate the efficacy of four posaconazole regimens compared with placebo in the treatment of toenail onychomycosis, to assess the safety and tolerability of posaconazole, and to estimate the relative efficacy of posaconazole against terbinafine.


METHODS
A phase 2B, randomized, placebo- and active-controlled, parallel-group, multicentre, investigator-blinded (double blind for placebo) study (ClinicalTrials.gov identifier: NCT00491764). Onychomycosis patients aged 18-75years (n=218) were randomized equally to one of six treatment regimens: posaconazole (oral suspension) 100, 200 or 400mg once daily (24weeks); posaconazole 400 mg once daily (12weeks); terbinafine (tablets) 250mg once daily (12weeks); or placebo (24weeks). The primary efficacy variable was complete cure (negative mycology and 0% nail involvement) at week 48.


RESULTS
All posaconazole treatment arms had a significantly (P≤0·012) greater proportion of patients with complete cure at week 48 compared with placebo. The proportions of patients with complete cure were numerically higher for posaconazole 200mg/24weeks (54·1%) and 400mg/24weeks (45·5%), but lower for 400mg/12weeks (20%) compared with terbinafine (37%; differences were not statistically significant). Posaconazole was well tolerated. Seven patients receiving posaconazole withdrew because of asymptomatic liver enzyme increases, as mandated by protocol discontinuation criteria.


CONCLUSIONS
The efficacy and favourable safety profile of posaconazole suggest a potential new treatment for onychomycosis. The availability of low-cost generic terbinafine may limit posaconazole use to second-line treatment of infections refractory to, or patients intolerant of, terbinafine, or nondermatophyte mould infections.
The role of microRNAs in respiratory viral infection: friend or foe?

MicroRNAs (miRNAs) have emerged as a class of regulatory RNAs in host-pathogen interactions. Aberrant miRNA expression seems to play a central role in the pathology of several respiratory viruses, promoting development and progression of infection. miRNAs may thus serve as therapeutic and prognostic factors for respiratory viral infectious disease caused by a variety of agents. We present a comprehensive review of recent findings related to the role of miRNAs in different respiratory viral infections and discuss possible therapeutic opportunities aiming to attenuate the burden of viral infections. Our review supports the emerging concept that cellular and viral-encoded miRNAs might be broadly implicated in human respiratory viral infections, with either positive or negative effects on virus life cycle. Copyright © 2016 John Wiley & Sons, Ltd.
Ethics, Children, and Biometric Technology

This article investigates suitable biometrics for the identification of children. It describes the different properties of a good biometric, and concludes with some recommendations regarding ethics and the use of biometrics for children.