LLukas22/scidocs huggingface dataset:
Utilization and expenditure at public and private facilities in 39 low-income countries.

OBJECTIVE
To document the patterns of health service utilization and health payments at public and private facilities across countries.


METHOD
We used data from the World Health Surveys from 39 low- and low-middle income countries to examine differences between public and private sectors. Utilization of outpatient and inpatient services, out-of-pocket payments (OOP) at public and private facilities, and transportation costs were compared.


RESULTS
Utilization and payments to public and private sectors differ widely. Public facilities dominated in most countries for both outpatient and inpatient services. But, whereas use of private facilities is more common among the rich, poor people also use them, to a considerable extent and in almost all the countries in the study. The majority of OOP were incurred at public providers for inpatient services. On average, this was not the case for outpatient services. Medicines accounted for the largest share of OOP for all services except inpatient services at private facilities, where consultation fees did. Transportation costs were considerable. Price competition is certainly not the only factor that guides choice of provider.


CONCLUSIONS
The results support continued efforts by the governments to engage strategically with the private sector. However, they also highlight the importance of not generalizing conditions across countries. Governments may need to reconsider simplistic user-fee abolition strategies at public providers if they simply focus on consultation fees. Policies to make health services more accessible need to consider a comprehensive benefit package that includes a wider scope of costs related to care such as expenditures on medicines and transportation.
A Microprocessor-based Hypercube Supercomputer

Each node in the NCUBE/ten parallel processor is organized around a custom, VAX-like, 32-bit CPU chip. With 1024 nodes, the NCUBE/ten provides a throughput of 500 MELOPS.
Retail service for mixed retail and E-tail channels

Together with regular retail channel, a firm can distribute products directly through Internet (referred to as an “e-tail” distribution channel). The competitive edge of the retail channel lies in more value-added services, some of which are unavailable through the e-tail channel. We consider a model mixed with retailing and e-tailing distribution channels where the service level and price decision are made, respectively, ex ante and ex post demand realizations. From the firm’s perspective of managing the two channels, we acquire the optimal decisions and characterize the effects of the demand uncertainty on the firm’s optimal retail service and expected profit. Applying stochastic comparison method, we show the firm’s retail service and profit both increase in the demand mean, and the firm profits from the increase of the convex order of the demand by decreasing his service level. Further, if the coefficient of the demand increases, we characterize that the firm benefits from it. Finally, several numerical studies are presented to gain insights.
Variation in mortality rates among long-term care facilities for residents with lower respiratory tract infection.

OBJECTIVE
To identify variables contributing to interfacility differences in mortality among residents of long-term care facilities who have lower respiratory tract infection.


DESIGN
Multicenter, prospective, 1-year observational study.


SETTING
Twenty-one long-term care facilities in 4 geographic areas of Canada.


PARTICIPANTS
Residents of long-term care facilities prescribed antimicrobials for treatment of lower respiratory tract infection.


METHODS
Mortality rates were calculated for 3 definitions of lower respiratory tract infection: episodes with a clinical or radiographic diagnosis and treated with antimicrobials (definition 1); episodes with a physician diagnosis of pneumonia (definition 2); and episodes with chest radiography findings consistent with pneumonia (definition 3). Multilevel modeling was used to evaluate variables describing premorbid resident status, clinical presentation, management, and facility characteristics. Multivariable models were developed to identify independent predictors of mortality and determine whether facility-level variables remained independently associated with mortality rate after incorporation of individual-level variables.


RESULTS
Facility mortality rates varied from 0% to 17.8% for definition 1, from 0% to 47.1% for definition 2, and from 0% to 37.5% for definition 3. There were significant differences in mortality rate depending on which definition was used; for definitions 1 and 2, there were significant differences in mortality rate across facilities. Poorer premorbid resident status and a more severe presentation remained independent predictors of mortality in the multivariable analysis. There were also significantly increased mortality rates for episodes in which a fluoroquinolone was prescribed for initial treatment. For definitions 1 and 3, facility-level variables remained independently associated with mortality rate in the final multivariable model.


CONCLUSIONS
Rates of mortality due to lower respiratory tract infection varied among long-term care facilities and differed within a facility, depending on the definition applied. Variables describing premorbid resident status, severity of presentation, and management did not fully explain the variation in mortality rate. Some facility-level variables remained independent predictors of mortality.
A small-size internal dual-band metal-strip antenna for 2.4/5 GHz WLAN operation in the laptop computer

This paper presents a novel small-size dual-band metal-strip antenna promising to operate as an internal laptop antenna for WLAN operation in the 2.4 and 5 GHz bands has been proposed, fabricated and tested. The antenna is especially suited to be employed in the narrow spacing between the top edge of the display panel and the casing of the laptop computer. The antenna is formed by using two inverted-L metal strips, including one driven strip and one parasitic shorted strip, stacked together to achieve a compact configuration, which is different from the traditional shorted T-shaped monopole antenna or planar inverted-F antenna. This compact configuration leads to a small lateral length of 20 mm for the proposed antenna. The antennapsilas two resonant modes can be easily fine-adjusted to cover the desired operating bands. For the fabricated prototype studied in the paper, good radiation characteristics over the 2.4 and 5 GHz bands have been obtained. It is perspective that the proposed antenna will become a promising internal antenna for 2.4/5 GHz WLAN operation for laptop computer applications.
The Cognitive Systems Paradigm

In this essay, I review the motivations behind the cognitive systems movement and attempt to characterize the paradigm. I propose six features that distinguish research in this framework from other approaches to artificial intelligence, after which I present some positive and negative examples in an effort to clarify the field’s boundaries. In closing, I also discuss some avenues for encouraging research in this critical area.
Surgical techniques: defibulation of Type III female genital cutting.

Female genital cutting (FGC) is a tradition practiced in parts of Africa, Middle East and Asia. Type III FGC, also known as infibulation, involves removing part or all of the external genitalia, generally, the prepuce, clitoris, labia minora, and majora. The remnant raw surfaces are sutured together (infibulated) using catgut sutures, thorns, or other adhesive concoctions to cover the urethra and most of the vagina. A stick is introduced in the posterior incision to guarantee a small opening (neo-introitus) for the passage of urine and menses. The girl’s legs are bound together for 1–2 weeks on bed rest with minimal oral intake to minimize urination and defecation in order to facilitate wound healing. Women who have undergone FGC can suffer immediate and long-term complications. Immediate complications include bleeding, hemorrhage, infection, sepsis, and death. Long-term complications include dysmenorrhea, dyspareunia, infertility, chronic vaginal, and urinary tract infections. Pre-op
A paradigm shift in the surgical reconstruction of extra-articular distal humeral fractures: single-column plating.

OBJECTIVES
The study aimed (1) to examine if there are equivalent results in terms of union, alignment and elbow functionally comparing single- to dual-column plating of AO/OTA 13A2 and A3 distal humeral fractures and (2) if there are more implant-related complications in patients managed with bicolumnar plating compared to single-column plate fixation.


DESIGN
This was a multi-centred retrospective comparative study.


SETTING
The study was conducted at two academic level 1 trauma centres.


PATIENTS/PARTICIPANTS
A total of 105 patients were identified to have surgical management of extra-articular distal humeral fractures Arbeitsgemeinschaft für Osteosynthesefragen/Orthopaedic Trauma Association (AO/OTA) 13A2 and AO/OTA 13A3).


INTERVENTION
Patients were treated with traditional dual-column plating or a single-column posterolateral small-fragment pre-contoured locking plate used as a neutralisation device with at least five screws in the short distal segment.


MAIN OUTCOME MEASUREMENTS
The patients' elbow functionality was assessed in terms of range of motion, union and alignment. In addition, the rate of complications between the groups including radial nerve palsy, implant-related complications (painful prominence and/or ulnar nerve neuritis) and elbow stiffness were compared.


RESULTS
Patients treated with single-column plating had similar union rates and alignment. However, single-column plating resulted in a significantly better range of motion with less complications.


CONCLUSIONS
The current study suggests that exposure/instrumentation of only the lateral column is a reliable and preferred technique. This technique allows for comparable union rates and alignment with increased elbow functionality and decreased number of complications.
Measuring goodness of story narratives.

PURPOSE
The purpose of this article was to evaluate a new measure of story narrative performance: story completeness. It was hypothesized that by combining organizational (story grammar) and completeness measures, story "goodness" could be quantified.


METHOD
Discourse samples from 46 typically developing adults were compared with those from 24 adults with acquired brain injuries. Story retellings were elicited and analyzed for episode structure (story grammar). Each story was also evaluated for the presence of 5 key components, yielding the story completeness score. Story goodness was quantified by combining the story grammar and completeness measures using a 2-coordinate grid system. A multivariate analysis of variance was performed as well as correlational analyses between the story grammar and story completeness scores.


RESULTS
There were significant group differences on both story grammar and story completeness. Moderate correlations were noted between the 2 measures, suggesting that the indices were not entirely measuring the same abilities. Plotting the 2 sets of scores into quadrants discriminated the comparison group and the group with brain injury into 4 distinct categories of story "goodness."


CONCLUSION
The combination of measures provided a more accurate depiction of discourse performance than either measure alone. Results suggest the measure is sensitive, is reliable, and has potential utility for investigating discourse deficits in clinical populations.
Biological explanations of generalized anxiety disorder: effects on beliefs about prognosis and responsibility.

OBJECTIVE
Biological explanations of psychopathology can reduce the extent to which people with mental disorders are blamed for their symptoms but can also yield prognostic pessimism--the belief that psychiatric conditions are relatively immutable. However, few studies have examined whether these effects occur among persons who actually have psychiatric symptoms. This study sought to address this question.


METHODS
Adults living in the United States (N=351) were recruited online in January and February 2012 and assessed for symptoms of generalized anxiety disorder. The participants were randomly assigned to two groups: a biological condition, in which participants (N=176) were provided a description of generalized anxiety disorder and a biological explanation of the etiology of the disorder, and a control condition, in which participants (N=175) were provided the same description without any explanation of etiology. Dependent measures of treatability, duration of symptoms, and responsibility for symptoms were used to gauge beliefs regarding the prognosis and personal responsibility of a typical person with generalized anxiety disorder.


RESULTS
Among participants with and without symptoms of generalized anxiety disorder, the biological condition was associated with decreased ascriptions of personal responsibility for anxiety (p=.02) and expectations of increased duration of symptoms of generalized anxiety disorder (p=.01).


CONCLUSIONS
This finding has important social and clinical implications, especially because biological conceptualizations of psychopathology are increasingly prevalent. By causing prognostic pessimism about generalized anxiety disorder, including among those with symptoms of the disorder, biological explanations could negatively affect treatment seeking and outcomes. Efforts to dispel the link between biological explanations and prognostic pessimism are needed.
Serum Proteomic Analysis Identifies a Highly Sensitive and Specific Discriminatory Pattern in Stage 1 Breast Cancer

Mass spectrometry (MS)-based profiling was used to determine whether ion fingerprints could distinguish women with stage 1 breast cancer from women without breast cancer. The initial study population consisted of 310 subjects: 155 women with yearly negative breast examination and negative mammography findings for at least 4 years, and 155 women undergoing surgery for pathology-proven stage 1 invasive ductal carcinoma. High-resolution SELDI-TOF (surface-enhanced laser desorption ionization–time of flight) analysis was performed on serum obtained from blood samples collected before mammography in controls, and before surgery in patients with breast cancer. Samples were divided into a training (109 controls and 109 cancers) and blinded (46 controls and 46 cancers) testing set; each group had similar age demographics. In addition, an independent study set of 46 serum samples was analyzed 14 months after the initial study to validate the robustness of the classifier. A discriminatory profile consisting of seven ion peaks found in the training set, when applied to the blinded test set, achieved a sensitivity and specificity of 95.6% and 86.5%, respectively. This same seven-peak profile achieved a 96.5% sensitivity and 85.7% specificity, with correct identification of all of 17 T1a tumors when applied to the validation study set. Mass spectrometry profiling of human serum generated a robust classifier composed of seven low-molecular-weight ions that yielded a highly sensitive and specific diagnostic procedure for the discrimination of women with stage 1 breast cancer compared with women without breast cancer in this research study set.
Liver Enzyme Abnormalities and Associated Risk Factors in HIV Patients on Efavirenz-Based HAART with or without Tuberculosis Co-Infection in Tanzania

OBJECTIVES
To investigate the timing, incidence, clinical presentation, pharmacokinetics and pharmacogenetic predictors for antiretroviral and anti-tuberculosis drug induced liver injury (DILI) in HIV patients with or without TB co-infection.


METHODS AND FINDINGS
A total of 473 treatment naïve HIV patients (253 HIV only and 220 with HIV-TB co-infection) were enrolled prospectively. Plasma efavirenz concentration and CYP2B6*6, CYP3A5*3, *6 and *7, ABCB1 3435C/T and SLCO1B1 genotypes were determined. Demographic, clinical and laboratory data were collected at baseline and up to 48 weeks of antiretroviral therapy. DILI case definition was according to Council for International Organizations of Medical Sciences (CIOMS). Incidence of DILI and identification of predictors was evaluated using Cox Proportional Hazards Model. The overall incidence of DILI was 7.8% (8.3 per 1000 person-week), being non-significantly higher among patients receiving concomitant anti-TB and HAART (10.0%, 10.7 per 1000 person-week) than those receiving HAART alone (5.9%, 6.3 per 1000 person-week). Frequency of CYP2B6*6 allele (p = 0.03) and CYP2B6*6/*6 genotype (p = 0.06) was significantly higher in patients with DILI than those without. Multivariate cox regression model indicated that CYP2B6*6/*6 genotype and anti-HCV IgG antibody positive as significant predictors of DILI. Median time to DILI was 2 weeks after HAART initiation and no DILI onset was observed after 12 weeks. No severe DILI was seen and the gain in CD4 was similar in patients with or without DILI.


CONCLUSIONS
Antiretroviral and anti-tuberculosis DILI does occur in our setting, presenting early following HAART initiation. DILI seen is mild, transient and may not require treatment interruption. There is good tolerance to HAART and anti-TB with similar immunological outcomes. Genetic make-up mainly CYP2B6 genotype influences the development of efavirenz based HAART liver injury in Tanzanians.
On Combining Crowdsourcing, Sensing and Open Data for an Accessible Smart City

This work presents a novel geospatial mapping service, based on OpenStreetMap, which has been designed and developed in order to provide personalized path to users with special needs. This system gathers data related to barriers and facilities of the urban environment via crowd sourcing and sensing done by users. It also considers open data provided by bus operating companies to identify the actual accessibility feature and the real time of arrival at the stops of the buses. The resulting service supports citizens with reduced mobility (users with disabilities and/or elderly people) suggesting urban paths accessible to them and providing information related to travelling time, which are tailored to their abilities to move and to the bus arrival time. The manuscript demonstrates the effectiveness of the approach by means of a case study focusing on the differences between the solutions provided by our system and the ones computed by main stream geospatial mapping services.
A search-based method for forecasting ad impression in contextual advertising

Contextual advertising (also called content match) refers to the placement of small textual ads within the content of a generic web page. It has become a significant source of revenue for publishers ranging from individual bloggers to major newspapers. At the same time it is an important way for advertisers to reach their intended audience. This reach depends on the total number of exposures of the ad (impressions) and its click-through-rate (CTR) that can be viewed as the probability of an end-user clicking on the ad when shown. These two orthogonal, critical factors are both difficult to estimate and even individually can still be very informative and useful in planning and budgeting advertising campaigns.
 In this paper, we address the problem of forecasting the number of impressions for new or changed ads in the system. Producing such forecasts, even within large margins of error, is quite challenging: 1) ad selection in contextual advertising is a complicated process based on tens or even hundreds of page and ad features; 2) the publishers' content and traffic vary over time; and 3) the scale of the problem is daunting: over a course of a week it involves billions of impressions, hundreds of millions of distinct pages, hundreds of millions of ads, and varying bids of other competing advertisers. We tackle these complexities by simulating the presence of a given ad with its associated bid over weeks of historical data. We obtain an impression estimate by counting how many times the ad would have been displayed if it were in the system over that period of time. We estimate this count by an efficient two-level search algorithm over the distinct pages in the data set. Experimental results show that our approach can accurately forecast the expected number of impressions of contextual ads in real time. We also show how this method can be used in tools for bid selection and ad evaluation.
Effectiveness of adjuvant occupational therapy in employees with depression: design of a randomized controlled trial

BACKGROUND
Major depressive disorder is among the medical conditions with the highest negative impact on work outcome. However, little is known regarding evidence-based interventions targeting the improvement of work outcomes in depressed employees. In this paper, the design of a randomized controlled trial is presented in order to evaluate the effectiveness of adjuvant occupational therapy in employees with depression. This occupational intervention is based on an earlier intervention, which was designed and proven effective by our research group, and is the only intervention to date that specifically targets work outcome in depressed employees.


METHODS/DESIGN
In a two-arm randomized controlled trial, a total of 117 participants are randomized to either 'care as usual' or ' care as usual' with the addition of occupational therapy. Patients included in the study are employees who are absent from work due to depression for at least 25% of their contract hours, and who have a possibility of returning to their own or a new job. The occupational intervention consists of six individual sessions, eight group sessions and a work-place visit over a 16-week period. By increasing exposure to the working environment, and by stimulating communication between employer and employee, the occupational intervention aims to enhance self-efficacy and the acquisition of more adaptive coping strategies. Assessments take place at baseline, and at 6, 12, and 18-month follow-ups. Primary outcome measure is work participation (hours of absenteeism and time until work resumption). Secondary outcome measures are work functioning, symptomatology, health-related quality of life, and neurocognitive functioning. In addition, cost-effectiveness is evaluated from a societal perspective. Finally, mechanisms of change (intermediate outcomes) and potential patient-treatment matching variables are investigated.


DISCUSSION
This study hopes to provide valuable knowledge regarding an intervention to treat depression, one of the most common and debilitating diseases of our time. If our intervention is proven (cost-) effective, the personal, economic, and health benefits for both patients and employers are far-reaching.


TRIAL REGISTRATION NUMBER
NTR2057.