LLukas22/scidocs huggingface dataset:
Incidence and clearance of anal high-risk human papillomavirus in HIV-positive men who have sex with men: estimates and risk factors.

BACKGROUND
To estimate incidence and clearance of high-risk human papillomavirus (HR-HPV), and their risk factors, in men who have sex with men (MSM) recently infected by HIV in Spain; 2007-2013.


METHODS
Multicenter cohort. HR-HPV infection was determined and genotyped with linear array. Two-state Markov models and Poisson regression were used.


RESULTS
We analysed 1570 HR-HPV measurements of 612 MSM over 13 608 person-months (p-m) of follow-up. Median (mean) number of measurements was 2 (2.6), median time interval between measurements was 1.1 years (interquartile range: 0.89-1.4). Incidence ranged from 9.0 [95% confidence interval (CI) 6.8-11.8] per 1000 p-m for HPV59 to 15.9 (11.7-21.8) per 1000 p-m for HPV51. HPV16 and HPV18 had slightly above average incidence: 11.9/1000 p-m and 12.8/1000 p-m. HPV16 showed the lowest clearance for both 'prevalent positive' (15.7/1000 p-m; 95% CI 12.0-20.5) and 'incident positive' infections (22.1/1000 p-m; 95% CI 11.8-41.1). More sexual partners increased HR-HPV incidence, although it was not statistically significant. Age had a strong effect on clearance (P-value < 0.001) due to the elevated rate in MSM under age 25; the effect of HIV-RNA viral load was more gradual, with clearance rate decreasing at higher HIV-RNA viral load (P-value 0.008).


CONCLUSION
No large variation in incidence by HR-HPV type was seen. The most common incident types were HPV51, HPV52, HPV31, HPV18 and HPV16. No major variation in clearance by type was observed, with the exception of HPV16 which had the highest persistence and potentially, the strongest oncogenic capacity. Those aged below 25 or with low HIV-RNA- viral load had the highest clearance.
Etiology of Non-Cystic Fibrosis Bronchiectasis in Adults and Its Correlation to Disease Severity.

RATIONALE
Testing for underlying etiology is a key part of bronchiectasis management, but it is unclear whether the same extent of testing is required across the spectrum of disease severity.


OBJECTIVES
The aim of the present study was to identify the etiology of bronchiectasis across European cohorts and according to different levels of disease severity.


METHODS
We conducted an analysis of seven databases of adult outpatients with bronchiectasis prospectively enrolled at the bronchiectasis clinics of university teaching hospitals in Monza, Italy; Dundee and Newcastle, United Kingdom; Leuven, Belgium; Barcelona, Spain; Athens, Greece; and Galway, Ireland. All the patients at every site underwent the same comprehensive diagnostic workup as suggested by the British Thoracic Society.


MEASUREMENTS AND MAIN RESULTS
Among the 1,258 patients enrolled, an etiology of bronchiectasis was determined in 60%, including postinfective (20%), chronic obstructive pulmonary disease related (15%), connective tissue disease related (10%), immunodeficiency related (5.8%), and asthma related (3.3%). An etiology leading to a change in patient's management was identified in 13% of the cases. No significant differences in the etiology of bronchiectasis were present across different levels of disease severity, with the exception of a higher prevalence of chronic obstructive pulmonary disease-related bronchiectasis (P < 0.001) and a lower prevalence of idiopathic bronchiectasis (P = 0.029) in patients with severe disease.


CONCLUSIONS
Physicians should not be guided by disease severity in suspecting specific etiologies in patients with bronchiectasis, although idiopathic bronchiectasis appears to be less common in patients with the most severe disease.
Vascular endothelial function and oxidative stress mechanisms in patients with Behçet's syndrome.

OBJECTIVES
We sought to test the hypothesis that vascular endothelial function is impaired in Behçet's syndrome and reflects increased levels of oxidative stress.


BACKGROUND
Behçet's syndrome is a multisystem inflammatory disorder commonly complicated by vascular thrombosis and arterial aneurysm formation. The precise mechanisms underlying vascular disease in Behçet's syndrome are not known.


METHODS
We studied 19 patients with Behçet's syndrome (18 to 50 years old, 9 men) and 21 healthy volunteers (18 to 50 years old, 10 men). Brachial artery flow-mediated dilation (endothelium-dependent), and nitroglycerin (NTG)-induced dilation (endothelium-independent) were measured. To investigate oxidative stress mechanisms, vascular studies were repeated 1 h after administration of vitamin C (1 g, intravenous) in 12 patients and 12 control subjects.


RESULTS
Flow-mediated dilation was reduced in patients with Behcet's syndrome as compared with control subjects (0.7 +/- 0.9% vs. 5.7 +/- 0.9%, p = 0.001). In contrast, there were no significant differences in the brachial artery diameter (4.2 +/- 0.2 vs. 4.0 +/- 0.2 mm, p = 0.47) or NTG-induced dilation (19.7 +/- 1.9% vs. 19.7 +/- 1.2%, p = 0.98). In regression analysis, Behçet's syndrome was associated with impaired flow-mediated dilation independent of age, gender, brachial artery diameter, blood pressure, cholesterol and glucose. Vitamin C increased flow-mediated dilation in Behçet's syndrome (0.2 +/- 0.7% to 3.5 +/- 1.0%, p = 0.002), but not in control subjects (4.3 +/- 0.6% to 4.7 +/- 0.4%, p = 0.51). In both groups, NTG-induced dilation and brachial artery diameter were unchanged after vitamin C treatment.


CONCLUSIONS
Vascular endothelial function is impaired in Behcet's syndrome and can be rapidly improved by vitamin C treatment. Our results support a role for oxidative stress in the pathophysiology of Behçet's syndrome and provide a rationale for therapeutic studies aimed at reducing vascular complications in this disorder.
Cortical midline structures and the self

For a long time philosophers and psychologists have been intrigued by the question of the self. More recently, this has become a topic of discussion in neuroscience. In this article, we suggest that the processing of self-referential stimuli in cortical midline structures (CMS) is a fundamental component in generating a model of the self. Drawing from neuroimaging studies, we distinguish between representation, monitoring, evaluation and integration of self-referential stimuli. All of these subfunctions are related to distinct regions within the CMS. This relationship between self-referential processing and CMS might provide novel insight into the neural correlates underlying the constitution of the self.
Electrophysiological correlates of block-wise strategic adaptations to consciously and unconsciously triggered conflict

The role of consciousness in conflict adaptation has been a topic of much debate. The purpose of the current study was to investigate the neural correlates of block-wise conflict adaptations elicited by conscious and unconscious conflicting stimuli in a meta-contrast masked priming task. Event-related potentials (ERPs) were recorded while individuals responded to prime-target pairs in mostly congruent (80% congruent trials, 20% incongruent trials) and mostly incongruent blocks of trials (20% congruent trials, 80% incongruent trials). Mean response times and error rates revealed that the conflict effect (incongruent trials-congruent trials) was reduced in mostly incongruent blocks relative to mostly congruent blocks. Furthermore, conflict related ERP signals (the amplitude difference between congruent and incongruent trials) for three ERP components (early occipito-parietal negativity, the fronto-central N2 and the centro-parietal P3) were attenuated in mostly incongruent blocks compared to mostly congruent blocks, reflecting block-wise adaptation to the frequency of conflict. The conflict-related frontal N2 component differentiated most strongly between visibility conditions. These results further specify the electrophysiological correlates of block-wise strategic adaptations to consciously and unconsciously elicited conflict.
Evaluation of the factors that determine quality in higher education : an empirical study

Purpose – The aim of this paper is to identify the quality determinants for education services provided by higher education institutions (HEIs) in Greece and to measure their relative importance from the students’ points of view. Design/mthodology/approach – A multi-criteria decision-making methodology was used for assessing the relative importance of quality determinants that affect student satisfaction. More specifically, the analytical hierarchical process (AHP) was used in order to measure the relative weight of each quality factor. Findings – The relative weights of the factors that contribute to the quality of educational services as it is perceived by students was measured. Research limitations/implications – The research is based on the questionnaire of the Hellenic Quality Assurance Agency for Higher Education. This implies that the measured weights are related mainly to questions posed in this questionnaire. However, the applied method (AHP) can be used to assess different quality determinants. Practical implications – The outcome of this study can be used in order to quantify internal quality assessment of HEIs. More specifically, the outcome can be directly used by HEIs for assessing quality as perceived by students. Originality/value – The paper attempts to develop insights into comparative evaluations of quality determinants as they are perceived by students.
A randomised controlled trial to compare the clinical and cost-effectiveness of prism glasses, visual search training and standard care in patients with hemianopia following stroke: a protocol

INTRODUCTION
Homonymous hemianopia is a common and disabling visual problem after stroke. Currently, prism glasses and visual scanning training are proposed to improve it. The aim of this trial is to determine the effectiveness of these interventions compared to standard care.


METHODS AND ANALYSIS
The trial will be a multicentre three arm individually randomised controlled trial with independent assessment at 6 week, 12 week and 26 week post-randomisation. Recruitment will occur in hospital, outpatient and primary care settings in UK hospital trusts. A total of 105 patients with homonymous hemianopia and without ocular motility impairment, visual inattention or pre-existent visual field impairment will be randomised to one of three balanced groups. Randomisation lists will be stratified by site and hemianopia level (partial or complete) and created using simple block randomisation by an independent statistician. Allocations will be disclosed to patients by the treating clinician, maintaining blinding for outcome assessment. The primary outcome will be change in visual field assessment from baseline to 26 weeks. Secondary measures will include the Rivermead Mobility Index, Visual Function Questionnaire 25/10, Nottingham Extended Activities of Daily Living, Euro Qual-5D and Short Form-12 questionnaires. Analysis will be by intention to treat.


ETHICS AND DISSEMINATION
This study has been developed and supported by the UK Stroke Research Network Clinical Studies Group working with service users. Multicentre ethical approval was obtained through the North West 6 Research ethics committee (Reference 10/H1003/119). The trial is funded by the UK Stroke Association. Trial Registration: Current Controlled Trials ISRCTN05956042. Dissemination will consider usual scholarly options of conference presentation and journal publication in addition to patient and public dissemination with lay summaries and articles.


TRIAL REGISTRATION
Current Controlled Trials ISRCTN05956042.
The influence of perceived value on purchase intention in social commerce context

Purpose – This study aims to examine the effects of perceived benefits, i.e. utilitarian value, hedonic value and social value, as well as perceived risk, on purchase intention in social commerce context. Design/methodology/approach – To cast light on the factors motivating users’ intention to purchase in the context of social commerce, 277 users of social commerce in China were collected via an online survey. Findings – Results show that satisfaction significantly and positively affects users’ purchase intention in social commerce context. In addition, utilitarian, hedonic and social values have significant and positive impacts on satisfaction and purchase intention; and utilitarian value is found to be the most salient factor influencing purchase intention, while hedonic value has the greatest effect on satisfaction. Moreover, perceived risk significantly and negatively affects satisfaction. Originality/value – Extant research on social commerce has mainly focused on investigating how the general perceived value affects user behavior, but has less considered different dimensions of perceived value. Also, prior studies have explored the roles of utilitarian and hedonic values on user behavior; however, there is a lack of research on the effect of social value. The current study attempts to fill these research gaps.
Long-term outcome of patients with clinical stage I high-risk nonseminomatous germ-cell tumors 15 years after one adjuvant cycle of bleomycin, etoposide, and cisplatin chemotherapy.

BACKGROUND
To report the long-term results of adjuvant treatment with one cycle of modified bleomycin, etoposide, and cisplatin (BEP) in patients with clinical stage I (CS I) nonseminomatous germ-cell tumors (NSGCT) at high risk of relapse.


PATIENTS AND METHODS
In a single-arm, phase II clinical trial, 40 patients with CS I NSGCT with vascular invasion and/or >50% embryonal cell carcinoma in the orchiectomy specimen received one cycle of adjuvant BEP (20 mg/m(2) bleomycin as a continuous infusion over 24 h, 120 mg/m(2) etoposide and 40 mg/m(2) cisplatin each on days 1-3). Primary end point was the relapse rate.


RESULTS
Median follow-up was 186 months. One patient (2.5%) had a pulmonary relapse 13 months after one BEP and died after three additional cycles of BEP chemotherapy. Three patients (7.5%) presented with a contralateral metachronous testicular tumor, and three (7.5%) developed a secondary malignancy. Three patients (7.5%) reported intermittent tinnitus and one had grade 2 peripheral polyneuropathy (2.5%).


CONCLUSIONS
Adjuvant chemotherapy with one cycle of modified-BEP is a feasible and safe treatment of patients with CS I NSGCT at high risk of relapse. In these patients, it appears to be an alternative to two cycles of BEP and to have a lower relapse rate than retroperitoneal lymph node dissection. If confirmed by other centers, 1 cycle of adjuvant BEP chemotherapy should become a first-line treatment option for this group of patients.
The Active Yakutat （Kula？） Plate and Its Southcentral Alaska Megathrust and Intraplate Earthquakes

Alaska geology and plate tectonics have not been well understood due to an active Yakutat plate, believed to be part of the remains of an ancient Kula plate, not being acknowledged to exist in Alaska. It is positioned throughout most of southcentral Alaska beneath the North American plate and above the NNW subducting Pacific plate. The Kula? plate and its eastern spreading ridge were partially “captured” by the North American plate in the Paleocene. Between 63 Ma and 32 Ma, large volumes of volcanics erupted from its subducted N-S striking spreading ridge through a slab window. The eruptions stopped at 32 Ma, likely due to the Pacific plate flat-slab subducting from the south beneath this spreading ridge. At 28 Ma, magmatism started again to the east; indicating a major shift to the east of this “refusing to die” spreading ridge. The captured Yakutat plate has also been subducting since 63 Ma to the WSW. It started to change to WSW flat-slab subduction at 32 Ma, which stopped all subduction magmatism in W and SW Alaska by 22 Ma. The Yakutat plate subduction has again increased with the impact/joining of the coastal Yakutat terrane from the ESE about 5 Ma, resulting in the Cook Inlet Quaternary volcanism of southcentral Alaska. During the 1964 Alaska earthquake, sudden movements along the southcentral Alaska thrust faults between the Yakutat plate and the Pacific plate occurred. Specifically, the movements consisted of the Pacific plate moving NNW under the buried Yakutat plate and of the coastal Yakutat terrane, which is considered part of the Yakutat plate, thrusting WSW onto the Pacific plate. These were the two main sources of energy release for the E part of this earthquake. Only limited movement between the Yakutat plate and the North American plate occurred during this 1964 earthquake event. Buried paleopeat age dates indicate the thrust boundary between the Yakutat plate and North American plate will move in about 230 years, resulting in a more “continental” type megathrust earthquake for southcentral Alaska. There are, therefore, at least two different types of megathrust earthquakes occurring in southcentral Alaska: the more oceanic 1964 type and the more continental type. In addition, large “active” WSW oriented strike-slip faults are recognized in the Yakutat plate, called slice faults, which represent another earthquake hazard for the region. These slice faults also indicate important oil/gas and mineral resource locations.
Feature-Based Indoor Navigation Using Augmented Reality

We present a prototype for indoor navigation using Augmented Reality that uses interior features to determine the user's location and provide navigation instructions. We test our prototype in a simulated physical shopping mall environment and find that AR-based navigation can provide usability advantages in indoor locations, particularly where targets are located on different floors. We conclude by recommending further work in presenting interior navigation instructions using AR.
Knowledge dissemination in operations management: Published perceptions versus academic reality

The channels for knowledge generation and dissemination in the business disciplines are many: presenting research at conferences, writing books, distributing working papers, offering insights in society newsletters, giving invited talks, publishing studies in academic journals, and many other venues, including even blogs and perhaps Facebook. But the most important venue is probably published research in ‘‘top-level’’ academic journals. In the discipline of Operations Management, many studies and lists have been published that attempt to determine which of these journals are supposedly the ‘‘top’’ according to either citation analyses, the opinion of recognized experts, author affiliations, bibliometric studies, and other approaches. These lists may then, in turn, be used in different degrees to evaluate research. However, what really counts is what the academic institutions actually use for guidance in evaluating faculty research. Based on a new source of ranking data from AACSB-accredited schools, we compare published journal-ranking studies against that of academe to determine the degree to which the studies reflect academic ‘‘reality’’. We present rankings of OM journals based on this new source of data and on an aggregate of the stream of published studies, and evaluate their consistency. & 2010 Elsevier Ltd. All rights reserved.
Some revisited results about composition operators on Hardy spaces

We generalize, on one hand, some results known for composition operators on Hardy spaces to the case of Hardy-Orlicz spaces H: construction of a “slow” Blaschke product giving a non-compact composition operator on H; construction of a surjective symbol whose composition operator is compact on H and, moreover, is in all the Schatten classes Sp(H ), p > 0. On the other hand, we revisit the classical case of composition operators on H, giving first a new, and simplier, characterization of closed range composition operators, and then showing directly the equivalence of the two characterizations of membership in the Schatten classes of Luecking and Luecking and Zhu. Mathematics Subject Classification. Primary: 47B33 – Secondary: 47B10 Key-words. Blaschke product – Carleson function – Carleson measure – composition operator – Hardy-Orlicz space – Nevanlinna counting function – Schatten classes
Optimization of Surface Roughness in End Milling on Mould Aluminium Alloys (AA6061-T6) Using Response Surface Method and Radian Basis Function Network

This paper is concerned with optimization of the surface roughness when milling Mould Aluminium alloys (AA6061-T6) with carbide coated inserts. Optimization of milling is very useful to reduce cost and time for machining mould. The approach is based on Response Surface Method (RSM) and Radian Basis Function Network (RBFN). RBFN was successfully used by Tsoa and Hocheng in their recent research. They used this network to predict thrust force and surface roughness in drilling. In this work, the objectives are to find the optimized parameters, and to find out the most dominant variables (cutting speed, federate, axial depth and radial depth). The optimized value has been used to develop a blow mould. The first order model and RBFN indicates that the feedrate is the most significant factors effecting surface roughness. RBFN predict surface roughness more accurately compared to RSM. © 2008 Jordan Journal of Mechanical and Industrial Engineering. All rights reserved
Web Image Re-Ranking Using Query-Specific Semantic Signatures

Image re-ranking, as an effective way to improve the results of web-based image search, has been adopted by current commercial search engines such as Bing and Google. Given a query keyword, a pool of images are first retrieved based on textual information. By asking the user to select a query image from the pool, the remaining images are re-ranked based on their visual similarities with the query image. A major challenge is that the similarities of visual features do not well correlate with images’ semantic meanings which interpret users’ search intention. In this paper, we propose a novel image re-ranking framework, which automatically offline learns different semantic spaces for different query keywords. The visual features of images are projected into their related semantic spaces to get semantic signatures. At the online stage, images are re-ranked by comparing their semantic signatures obtained from the semantic space specified by the query keyword. The proposed query-specific semantic signatures significantly improve both the accuracy and efficiency of image re-ranking
Depiction of residual emboli following pulmonary embolism with thrombotic scintigraphy.

BACKGROUND
In the treatment of pulmonary embolism (PE), the presence of residual emboli is known to seriously affect the recurrence and prognosis. We attempted to depict the residual emboli in the subacute stage of PE using indium-111-oxine labeled platelet scintigraphy (In-plt).


METHODS
In-plt was performed on 22 patients with PE who showed an improvement according to lung perfusion scintigraphy. Their accumulation was assessed along with the blood coagulation ability measured on the same day. In addition, radioisotope venography (RI-veno) was performed simultaneously with In-plt to measure the circulatory findings in the lower limb for comparison. All patients received systemic heparin during the acute stage and received warfarin at the time of testing.


RESULTS
Accumulation of In-pit was observed in 7 patients (32%), and positive signals were found in the lower limbs or pelvic cavity in all cases. Two patients were suspected of having poor lower limb circulation from their RI-veno findings, and these findings were largely consistent with the areas of In-plt accumulation.


DISCUSSION
Some emboli persist after extensive anti-coagulation therapy. The use of In-pit is effective in determining the therapeutic measures and assessing the prognosis as this method allows us to clearly depict the existence of such emboli.