LLukas22/scidocs huggingface dataset:
Diuretics and mortality in acute renal failure.

OBJECTIVE
According to recent research, diuretics may increase mortality in acute renal failure patients. The administration of diuretics in such patients has been discouraged. Our objective was to determine the impact of diuretics on the mortality rate of critically ill patients with acute renal failure.


DESIGN
Prospective, multiple-center, multinational epidemiologic study.


SETTING
Intensive care units from 54 centers and 23 countries.


PATIENTS
Patients were 1,743 consecutive patients who either were treated with renal replacement therapy or fulfilled predefined criteria for acute renal failure.


INTERVENTIONS
Three distinct multivariate models were developed to assess the relationship between diuretic use and subsequent mortality: a) a propensity score adjusted multivariate model containing terms previously identified to be important predictors of outcome; b) a new propensity score adjusted multivariate model; and c) a multivariate model developed using standard methods, compensating for collinearity.


MEASUREMENTS AND MAIN RESULTS
Approximately 70% of patients were treated with diuretics at study inclusion. Mean age was 68 and mean Simplified Acute Physiology Score II was 47. Severe sepsis/septic shock (43.8%), major surgery (39.1), low cardiac output (29.7), and hypovolemia (28.2%) were the most common conditions associated with the development of acute renal failure. Furosemide was the most common diuretic used (98.3%). Combination therapy was used in 98 patients only. In all three models, diuretic use was not associated with a significantly increased risk of mortality.


CONCLUSIONS
Diuretics are commonly prescribed in critically ill patients with acute renal failure, and their use is not associated with higher mortality. There is full equipoise for a randomized controlled trial of diuretics in critically ill patients with renal dysfunction.
Abstractive text summarization using LSTM-CNN based deep learning

Abstractive Text Summarization (ATS), which is the task of constructing summary sentences by merging facts from different source sentences and condensing them into a shorter representation while preserving information content and overall meaning. It is very difficult and time consuming for human beings to manually summarize large documents of text. In this paper, we propose an LSTM-CNN based ATS framework (ATSDL) that can construct new sentences by exploring more fine-grained fragments than sentences, namely, semantic phrases. Different from existing abstraction based approaches, ATSDL is composed of two main stages, the first of which extracts phrases from source sentences and the second generates text summaries using deep learning. Experimental results on the datasets CNN and DailyMail show that our ATSDL framework outperforms the state-of-the-art models in terms of both semantics and syntactic structure, and achieves competitive results on manual linguistic quality evaluation.
Tool wear condition monitoring using a sensor fusion model based on fuzzy inference system

One of the biggest problems in manufacturing is the failure of machine tools due to loss of surface material in cutting operations like drilling and milling. Carrying on the process with a dull tool may damage the workpiece material fabricated. On the other hand, it is unnecessary to change the cutting tool if it is still able to continue cutting operation. Therefore, an effective diagnosis mechanism is necessary for the automation of machining processes so that production loss and downtime can be avoided. This study concerns with the development of a tool wear condition-monitoring technique based on a two-stage fuzzy logic scheme. For this, signals acquired from various sensors were processed to make a decision about the status of the tool. In the first stage of the proposed scheme, statistical parameters derived from thrust force, machine sound (acquired via a very sensitive microphone) and vibration signals were used as inputs to fuzzy process; and the crisp output values of this process were then taken as the input parameters of the second stage. Conclusively, outputs of this stage were taken into a threshold function, the output of which is used to assess the condition of the tool. r 2008 Elsevier Ltd. All rights reserved.
Influence of lifestyle on overweight and obesity in school-age children.

INTRODUCTION
Special attention needs to be given to resolution of obesity problem among children because many studies indicate that majority of persons that have suffered from obesity during their child age still have the same problems when they become adults. Incorrect nutritional habits cause health problems at later age. The purpose of this study is to determine the frequency of overweight and obesity occurrence among school-age children, as well as risk factors that certainly lead to obesity.


METHODS
This research was conducted on sample of 530 pupils from one elementary school from suburban area. Assessed children were from seven to fourteen years old. Anthropometric measurements were taken and questionnaires and general medical examinations followed with the statistical processing of collected data.


RESULTS
Based on the Body Mass Index (BMI) considering age and gender of examined subjects we have found that 14.7% subjects were overweight and 7.3% of children were obese. Also, we have determined that children often use food that is identified as risk factor for obesity. Overweight and obesity are directly related to amount of time spent in front of TV set or personal computer (p = 0.01). Children that were overweight in 57.1% cases would prefer to change their nutritional habits and 68.4% of obese children would like to do so as well. Children that were obese, in high percent would like to change habits regarding their physical activity (57.9% of them) and overweight children in 33.8% cases.


CONCLUSION
It is necessary to encourage young people to develop healthy nutritional habits, to promote physical activity and sports, and definitely to strongly advice against the sedentary lifestyle. It is crucial to educate parents on healthy nutritional habits and physical activity because they have the strongest influence on their children. Also, effort needs to be taken in schools by increasing number of physical education classes and to provide healthy food in school canteens in order to ensure improvement of physical activity and healthy nutritional habits among children.
Multicenter review of diaphragm pacing in spinal cord injury: successful not only in weaning from ventilators but also in bridging to independent respiration.

BACKGROUND
Ventilator-dependent spinal cord-injured (SCI) patients require significant resources related to ventilator dependence. Diaphragm pacing (DP) has been shown to successfully replace mechanical ventilators for chronic ventilator-dependent tetraplegics. Early use of DP following SCI has not been described. Here, we report our multicenter review experience with the use of DP in the initial hospitalization after SCI.


METHODS
Under institutional review board approval for humanitarian use device, we retrospectively reviewed our multicenter nonrandomized interventional protocol of laparoscopic diaphragm motor point mapping with electrode implantation and subsequent diaphragm conditioning and ventilator weaning.


RESULTS
Twenty-nine patients with an average age of 31 years (range, 17-65 years) with only two females were identified. Mechanism of injury included motor vehicle collision (7), diving (6), gunshot wounds (4), falls (4), athletic injuries (3), bicycle collision (2), heavy object falling on spine (2), and motorcycle collision (1). Elapsed time from injury to surgery was 40 days (range, 3-112 days). Seven (24%) of the 29 patients who were evaluated for the DP placement had nonstimulatable diaphragms from either phrenic nerve damage or infarction of the involved phrenic motor neurons and were not implanted. Of the stimulatable patients undergoing DP, 72% (16 of 22) were completely free of ventilator support in an average of 10.2 days. For the remaining six DP patients, two had delayed weans of 180 days, three had partial weans using DP at times during the day, and one patient successfully implanted went to a long-term acute care hospital and subsequently had life-prolonging measures withdrawn. Eight patients (36%) had complete recovery of respiration, and DP wires were removed.


CONCLUSION
Early laparoscopic diaphragm mapping and DP implantation can successfully wean traumatic cervical SCI patients from ventilator support. Early laparoscopic mapping is also diagnostic in that a nonstimulatable diaphragm is a convincing evidence of an inability to wean from ventilator support, and long-term ventilator management can be immediately instituted.


LEVEL OF EVIDENCE
Therapeutic study, level V.
How low can it go? Projecting ischaemic heart disease mortality in New Zealand to 2015.

AIMS
This study aims to identify how ischaemic heart disease (IHD) mortality rates in New Zealand have varied between successive cohorts and time periods. This information is then used to project IHD mortality rates and counts (burdens) out to year 2011-15.


METHODS
Age/period/cohort models were constructed (5-year periods and 5-year age groups, generating 10-year overlapping cohorts) using both frequentist and Bayesian methods. Data were available from 1956 for the total population and from 1981 for Maori. The projection period was 2001-5 to 2011-15. Uncertainty was quantified as the Bayesian 90% credible interval.


RESULTS
IHD mortality rates for all age by gender groups increased from 1956-60 to peak in 1966-70, then declined by more than 60% to current (1996-2000) levels. However, the decline has been much shallower for Maori. This decline has resulted from increasingly favourable period effects since 1971-75 (less marked for Maori). However, no substantive cohort effects have been seen, at least from the 1891 to the 1951 cohort. Our model suggests that, for the first time, a substantive and unfavourable cohort effect may be emerging among recent birth cohorts.


CONCLUSIONS
IHD mortality rates are projected to continue to fall from 2001-05 to 2011-15, albeit more slowly than in the past as the increasing (favourable) period effect is partly offset by an emerging (unfavourable) cohort effect. The result is a relatively small projected decline in absolute IHD mortality burden overall, but an actual increase among Maori.
Changes in mental state associated with prison environments: a systematic review.

OBJECTIVE
To develop an understanding of the stability of mental health during imprisonment through review of existing research evidence relating physical prison environment to mental state changes in prisoners.


METHOD
A systematic literature search was conducted looking at changes in mental state and how this related to various aspects of imprisonment and the prison environment.


RESULTS
Fifteen longitudinal studies were found, and from these, three broad themes were delineated: being imprisoned and aspects of the prison regime; stage of imprisonment and duration of sentence; and social density. Reception into prison results in higher levels of psychiatric symptoms that seem to improve over time; otherwise, duration of imprisonment appears to have no significant impact on mental health. Regardless of social density, larger prisons are associated with poorer mental state, as are extremes of social density.


CONCLUSION
There are large gaps in the literature relating prison environments to changes in mental state; in particular, high-quality longitudinal studies are needed. Existing research suggests that although entry to prison may be associated with deterioration in mental state, it tends to improve with time. Furthermore, overcrowding, ever more likely as prison populations rise, is likely to place a particular burden on mental health services.
Measuring the Costs and Benefits of Crime and Justice

Cost-effectiveness and benefit-cost analyses are tools that have been used by public policy analysts for years. Programs as diverse as environmental and land use regulations, welfare benefits, job training programs, and immunization policies have all been analyzed in this manner. Since the early 1980s, Federal regulatory agencies have been required to conduct benefit-cost analyses on major regulatory initiatives. Despite their widespread use, cost-effectiveness and benefitcost analyses have not been staples of the criminal justice policy analyst’s tool kit. This is rapidly changing in response to both increasing public demand for accountability of government agencies and the availability of new data and analysis techniques for identifying the costs of crime. This chapter reviews state-of-the-art techniques for estimating the costs and benefits of criminal justice and prevention programs. Although official government estimates of the cost of street crime have been available for many years, recent studies have attempted to go beyond government statistics by incorporating the monetary value of pain, suffering, and lost quality of life. Many of these studies use methodologies that are employed by environmental, health, and safety economists. Because these methodologies are new to the criminal justice research community, considerable attention is given to understanding their underlying assumptions, limitations, and alternatives. Cost-benefit analysis has arrived in the criminal justice policy arena, and it will not go away. Forcing analysts to quantify MEASUREMENT AND ANALYSIS OF CRIME AND JUSTICE
Political tuning in Ankara, a capital, as reflected in its urban symbols and images

Determining the 'tensions, conflicts and social changes' in the city through symbolic configurations and shifting images has been a recent dimension in the study of urban culture. This is the perspective taken in this article. A brief introduction of Turkey and Ataturk is followed by a study of urban symbols. Starting with those of the Ottoman period, these include monuments and statues; the names of city squares, parks and shops; and the street names and official city emblems since the settlement became the capital in 1923. The city itself was the symbol of national independence and the new republic in the 1920s and 1930s. Fluctuations over the years, in the preference for certain names or artefacts, reflect the shifts from nation-building to clashes of political ideologies and, more recently, an 'identity crisis' that the nation has overtly been experiencing. The study is based on observations that are supported by publications from libraries and private collections, including memoirs. Further material has been provided by informal talks with people from all backgrounds, including the recollections of the author Erdentug, who has lived in the city since 1956, and the reminiscences of her parents commencing twenty years before this date. Copyright Joint Editors and Blackwell Publishers Ltd 1998.
SPADE: Support for Provenance Auditing in Distributed Environments

SPADE is an open source software infrastructure for data provenance collection and management. The underlying data model used throughout the system is graph-based, consisting of vertices and directed edges that are modeled after the node and relationship types described in the Open Provenance Model. The system has been designed to decouple the collection, storage, and querying of provenance metadata. At its core is a novel provenance kernel that mediates between the producers and consumers of provenance information, and handles the persistent storage of records. It operates as a service, peering with remote instances to enable distributed provenance queries. The provenance kernel on each host handles the buffering, filtering, and multiplexing of incoming metadata from multiple sources, including the operating system, applications, and manual curation. Provenance elements can be located locally with queries that use wildcard, fuzzy, proximity, range, and Boolean operators. Ancestor and descendant queries are transparently propagated across hosts until a terminating expression is satisfied, while distributed path queries are accelerated with provenance sketches.
Effects of xanthine oxidase inhibition with allopurinol on endothelial function and peripheral blood flow in hyperuricemic patients with chronic heart failure: results from 2 placebo-controlled studies.

BACKGROUND
In patients with chronic heart failure (CHF), hyperuricemia is a common finding and is associated with reduced vasodilator capacity and impaired peripheral blood flow. It has been suggested that the causal link of this association is increased xanthine oxidase (XO)-derived oxygen free radical production and endothelial dysfunction. We therefore studied the effects of XO inhibition with allopurinol on endothelial function and peripheral blood flow in CHF patients after intra-arterial infusion and after oral administration in 2 independent placebo-controlled studies.


METHODS AND RESULTS
In 10 CHF patients with normal serum uric acid (UA) levels (315+/-42 micromol/L) and 9 patients with elevated UA (535+/-54 micromol/L), endothelium-dependent (acetylcholine infusion) and endothelium-independent (nitroglycerin infusion) vasodilation of the radial artery was determined. Coinfusion of allopurinol (600 microg/min) improved endothelium-dependent but not endothelium-independent vasodilation in hyperuricemic patients (P<0.05). In a double-blind, crossover design, hyperuricemic CHF patients were randomly allocated to allopurinol 300 mg/d or placebo for 1 week. In 14 patients (UA 558+/-21 micromol/L, range 455 to 743 micromol/L), treatment reduced UA by >120 micromol/L in all patients (mean reduction 217+/-15 micromol/L, P<0.0001). Compared with placebo, allopurinol improved peak blood flow (venous occlusion plethysmography) in arms (+24%, P=0.027) and legs (+23%, P=0.029). Flow-dependent flow improved by 58% in arms (P=0.011). Allantoin, a marker of oxygen free radical generation, decreased by 20% after allopurinol treatment (P<0.001). There was a direct relation between change of UA and improvement of flow-dependent flow after allopurinol treatment (r=0.63, P<0.05).


CONCLUSIONS
In hyperuricemic CHF patients, XO inhibition with allopurinol improves peripheral vasodilator capacity and blood flow both locally and systemically.
Microscopic derivation of the effective Lagrangian for skyrmions in an interacting two-dimensional electron gas at small g -factor

and quantize the problem, assuming the standard commuta-tion relations P i X i   i" h to be fulfilled. This yields the cyclotron frequency of the skyrmion as a whole " ho s  2g and the minimum energy E s  g. Thus, in experiments the skyrmion should exhibit a cyclotron resonance at a frequency 2g. The quantity g is determined as the exchange energy per electron, in the case of a completely filled Landau level g  e 2 l B   2p p X The energy g must be added to expression (5) obtained above for the total energy. It is also interesting to find a term with the Hopf invariant in the action which, according to modern views, determines the skyrmion statistics [11]. For this purpose we should calculate the terms containing one time-dependent O l t and two space-dependent O l in the expansion of the action in terms of O l. Calculations up to the third order are rather cumbersome and require the consideration of numerous diagrams, the second-order diagrams also contributing, since their non-local character in time and space must be taken into account [9, 10]. We present only the final result corresponding to thèfermion' character of vortex-sky-rmions:  e ljm O t O j Â O l d 2 r dt Y 7 where e ljm is the unit antisymmetric third-rank tensor. The integer Hopf invariant H is expressed in terms of O l [12]. This result does not coincide with that obtained within the method of Landau functions projected onto the zero level [7] which is a sum of several spatial derivatives. At the same time, formula (7) has a standard form and agrees with that suggested in note [13]. In conclusion we emphasize once again that the solution of differential equations of the Hartree ± Fock approximation is necessary, since it determines the discrepancy between our results and those obtained by projection onto a single Landau level, when the differential form of the kinetic energy in the SchroÈ dinger equation is replaced by a constant energy. It is of special importance in the calculation of the thermodynamic energy of the vortex-skyrmion where the additional term À" ho c a2Q appears, which can lead to spontaneous appearance of vortices and a rearrangement of the ground state in a rather strong magnetic field.
Defining Artificial Intelligence

1.1 BACKGROUND Calculators are not intelligent. Calculators give the right answers to challenging math problems, but everything they " know " is preprogrammed by people. They can never learn anything new, and outside of their limited domain of utility, they have the expertise of a stone. Calculators are able to solve problems entirely because people are already able to solve those same problems. Since the earliest days of computing, we have envisioned machines that could go beyond our own ability to solve problems—intelligent machines. We have generated many computing devices that can solve mathematical problems of enormous complexity, but mainly these too are merely " calculators. " They are prepro-grammed to do exactly what we want them to do. They accept input and generate the correct output. They may do it at blazingly fast speeds, but their underlying mechanisms depend on humans having already worked out how to write the programs that control their behavior. The dream of the intelligent machine is the vision of creating something that does not depend on having people preprogram its problem solving behavior. Put another way, artificial intelligence should not seek to merely solve problems, but should rather seek to solve the problem of how to solve problems. Although most scientific disciplines, such as mathematics, physics, chemistry, and biology, are well defined, the field of artificial intelligence (AI) remains enigmatic. This is nothing new. Even 20 years ago, Hofstadter (1985, p. 633) remarked, " The central problem of AI is the question: What is the letter 'a'? Donald Knuth, on hearing me make this claim once, appended, 'And what is the letter 'i'?'—an amendment that I gladly accept. " Despite nearly 50 years of research in the field, there is still no widely accepted definition of artificial intelligence. Even more, a discipline of computational intelligence—including research in neural networks, fuzzy systems, and evolutionary computation—has gained prominence as an alternative to AI, mainly because AI has failed to live up to its promises and because many believe that the methods that have been adopted under the old rubric of AI will never succeed. It may be astonishing to find that five decades of research in artificial intelligence have been pursued without fundamentally accepted goals, or even a simple