LLukas22/scidocs huggingface dataset:
Better together? a naturalistic qualitative study of inter-professional working in collaborative care for co-morbid depression and physical health problems

BACKGROUND
Mental-physical multi-morbidities pose challenges for primary care services that traditionally focus on single diseases. Collaborative care models encourage inter-professional working to deliver better care for patients with multiple chronic conditions, such as depression and long-term physical health problems. Successive trials from the United States have shown that collaborative care effectively improves depression outcomes, even in people with long-term conditions (LTCs), but little is known about how to implement collaborative care in the United Kingdom. The aim of the study was to explore the extent to which collaborative care was implemented in a naturalistic National Health Service setting.


METHODS
A naturalistic pilot study of collaborative care was undertaken in North West England. Primary care mental health professionals from IAPT (Increasing Access to Psychological Therapies) services and general practice nurses were trained to collaboratively identify and manage patients with co-morbid depression and long-term conditions. Qualitative interviews were performed with health professionals at the beginning and end of the pilot phase. Normalization Process Theory guided analysis.


RESULTS
Health professionals adopted limited elements of the collaborative care model in practice. Although benefits of co-location in primary care practices were reported, including reduced stigma of accessing mental health treatment and greater ease of disposal for identified patients, existing norms around the division of mental and physical health work in primary care were maintained, limiting integration of the mental health practitioners into the practice setting. Neither the mental health practitioners nor the practice nurses perceived benefits to joint management of patients.


CONCLUSIONS
Established divisions between mental and physical health may pose particular challenges for multi-morbidity service delivery models such as collaborative care. Future work should explore patient perspectives about whether greater inter-professional working enhances experiences of care. The study demonstrates that research into implementation of novel treatments must consider how the introduction of innovation can be balanced with the need for integration into existing practice.
A Simple Weather Forecasting Model Using Mathematical Regression

A simple model for weather forecasting has been described. The model is simple due to the fact that it uses simple mathematical equation using Multiple Linear Regression (MLR) equations that can be easily understood by a medium educated farmer. Weather data at a particular station is recorded which is a time-series data. The weather parameters like maximum temperature, minimum temperature and relative humidity have been predicted using the calculated features depending upon the correlation values in the weather data series over different periods from the weather parameter time-series itself. Relative humidity is also predicted using time series of maximum and minimum temperature and rainfall. The category of rainfall has been estimated using features of maximum and minimum temperature and relative humidity. The development phase of the model is to obtain MLR equations using input set and output parameter. The coefficients of these regression equations have been used to estimate the future weather conditions. The personal computer and simple data processing software like MS Excel can be used to make and validate the model by the user itself. The results obtained show that MLR model can estimate the weather conditions satisfactorily.
Immunization of pregnant sows with a novel virulence gene deleted live Salmonella vaccine and protection of their suckling piglets against salmonellosis.

This study was carried out to examine a novel Salmonella Typhimurium (S. Typhimurium) vaccine for protection of suckling piglets against salmonellosis by immunization of pregnant sows using various administration routes. The vaccine strain was constructed by deletion of cpxR and lon from a wild type S. Typhimurium and the S. Typhimurium Delta cpxR Delta lon Delta asd secreting the B subunit of the Escherichia coli heat-labile enterotoxin were used as a live form of mucosal adjuvant for this study. Pregnant sows were divided into 4 groups of 3 sows a piece. Sows were primed at 8 weeks of pregnancy and were boosted 11 weeks of pregnancy. Group A sows were primed intramuscularly with the formalin-inactivated vaccine and boosted orally with the live vaccine and mucosal adjuvant, group B sows were orally primed with the live vaccine and mucosal adjuvant and boosted orally with live vaccine, group C sows were orally primed with live vaccine and mucosal adjuvant and intramuscularly boosted, and group D sows were primed and boosted with phosphate-buffered saline as controls. Piglets were orally challenged with a virulent S. Typhimurium strain at day 6 after birth. Sows from group A and B had significantly increased IgG levels compared to control group sows (P<0.05), and group C sows had lower IgG levels compared to group A and B sows. Mucosal sIgA and IgG levels in group A and B sow colostrums were significantly increased as compared to those of group D sows (P<0.05). Serum IgG and IgA levels in group A and B piglets were also significantly increased as compared to those of group D piglets (P<0.001). These data suggested that systemic and mucosal immune responses were highly induced by the vaccine candidate, especially when this was administered by both routes of intramuscular-prime and oral booster, and oral prime and booster. Furthermore, clinical signs such as diarrhea and weight loss were not observed after virulent Salmonella strain challenge in group A and B suckling piglets, however, group C (41.7%) and group D (83.3%) piglets suffered from diarrhea. This data suggested that sow immunized by intramuscular-prime and oral booster and oral prime and oral booster with this vaccine candidate effectively protected piglets from salmonellosis.
Impact of parathyroidectomy on serum FGF23 and soluble Klotho in hemodialysis patients with severe secondary hyperparathyroidism.

CONTEXT
Klotho is a transmembrane protein that functions as a coreceptor for fibroblast growth factor 23 (FGF23). Klotho is cleaved and released into the circulation; however, the main site of production, physiological role, and regulation of soluble Klotho in humans are largely unknown.


OBJECTIVE
The aim of this study was to determine the impact of parathyroidectomy (PTx) on serum FGF23 and soluble Klotho levels in patients with severe secondary hyperparathyroidism.


DESIGN AND SETTING
This was a prospective, single-arm trial conducted at Tokai University School of Medicine.


PATIENTS
Thirteen hemodialysis patients with severe secondary hyperparathyroidism who were candidates for PTx participated in the study.


INTERVENTIONS
All patients underwent total PTx with forearm autotransplantation.


MAIN OUTCOME MEASURES
We evaluated changes in serum FGF23 and soluble Klotho levels for 90 days after PTx. Other biochemical parameters related to mineral and bone metabolism were also assessed.


RESULTS
At baseline, serum FGF23 levels were markedly elevated, whereas serum soluble Klotho levels were modestly decreased. PTx resulted in a marked, progressive decline in serum FGF23 levels together with significant reductions in serum calcium, phosphorus, and intact PTH levels. The serum soluble Klotho levels were reduced 13% from baseline on the day after PTx; however, these levels then increased progressively, reaching 34% above the postoperative values.


CONCLUSIONS
Our results suggest that the parathyroid gland is not the major site of soluble Klotho production in patients with end-stage renal disease, and the production of Klotho by other organ(s) is affected by alterations in mineral metabolism or medications taken after PTx.
Fuzzy Logic Cross-coupling Control of Wheeled Mobile Robots

In order to decrease the orientation error induced by motion control of a differential-drive mobile robot, a fuzzy logic cross-coupling motion controller that integrates the cross-coupling control and fuzzy logic techniques together is presented. Cross-coupling control can directly minimize the orientation error by coordinating the motion of the two drive wheels. Experimental results show that the proposed fuzzy logic cross-coupling controller can be successfully applied to enhancing the motion accuracy of the robot. It is also demonstrated that the performance of the fuzzy logic cross-coupling control scheme is superior to the conventional PID cross-coupling control scheme
Physical browsing with NFC technology

Physical browsing is a new intuitive human computer interfacing paradigm for mobile users. Services, such as information retrieval, peer to peer communication, payment or ticketing, and professional applications can be initiated by simply touching an object with a users personal device. This paradigm can be implemented with RFID technology. A number of major companies in the fields of mobile communications, electronics and financing have joined forces in an effort to commercialise this human computer interaction paradigm with the brand name Near Field Communication (NFC). NFC is based on existing technology using 13.56 MHz RFIDs and international standards. NFC forum is creating standards and recommendations for the upper level protocols and application models. VTT is leading a European-wide project which develops and pilots NFC technology. This report describes the findings and results of the first project year. The report outlines the concept of Physical browsing, NFC technology, its main applications, and describes a pilot case with a meal service for elderly citizens. An NFC Bluetooth gateway prototype has been designed and the first experiments are briefly described. Security and privacy issues relevant to NFC are described. The main business models, namely those driven by financial institutions, mobile operators or other parties, are discussed. A look at major trials and roll-outs of contactless payment is given. Some solutions to the dilemma of scarce NFC services and low penetration of NFC phones are suggested.
Product-driven supply chain selection using integrated multi-criteria decision-making methodology

Effective supply chain design calls for robust analytical models and design tools. Previous works in this area are mostly Operation Research oriented without considering manufacturing aspects. Recently, researchers have begun to realize that the decision and integration effort in supply chain design should be driven by the manufactured product, specifically, product characteristics and product life cycle. In addition, decision-making processes should be guided by a comprehensive set of performance metrics. In this paper, we relate product characteristics to supply chain strategy and adopt supply chain operations reference (SCOR) model level I performance metrics as the decision criteria. An integrated analytic hierarchy process (AHP) and preemptive goal programming (PGP) based multi-criteria decision-making methodology is then developed to take into account both qualitative and quantitative factors in supplier selection. While the AHP process matches product characteristics with supplier characteristics (using supplier ratings derived from pairwise comparisons) to qualitatively determine supply chain strategy, PGP mathematically determines the optimal order quantity from the chosen suppliers. Since PGP uses AHP ratings as input, the variations of pairwise comparisons in AHP will influence the final order quantity. Therefore, users of this methodology should put greater emphasis on the AHP progress to ensure the accuracy of supplier ratings. r 2003 Elsevier B.V. All rights reserved.
The effect of boron content on the microstructure and mechanical properties of Fe50-XMn30Co10Cr10BX (x = 0, 0.3, 0.6 and 1.7 wt%) multi-component alloys prepared by arc-melting

Abstract High and Medium- Entropy Alloys (HEAs and MEAs) are a novel type of materials, which due to the reduction in configurational entropy, can offer an excellent combination of properties, such as, high strength, high ductility and moderate hardness. During the study, four alloys based on Fe 50-X Mn 30 Co 10 Cr 10 B X system (x = 0, 0.3, 0.6 and 1.7 wt%) were manufactured by arc melting. The microstructure of the materials was analyzed by optical microscopy, scanning electron microscopy, and X-ray diffraction. The Vickers microhardness of these alloys were also measured. Detailed characterization revealed the formation of a dual-phase matrix (fcc + hcp) due to the reduction in the stability of the fcc phase that led to a thermal induced partial martensitic transformation into a e-hcp phase. The addition of boron promoted the formation of M 2 B-type borides (M = Cr, Fe), whose content increased with the addition of B. Changes in the phase composition, specifically the decrease of the hcp phase, were mainly due to the loss of manganese content. The microstrain analysis showed the absence of residual stresses in the crystal lattice due to a decrease in the dislocation’s density after the martensitic transformation. When boron content was brought from 0 wt% to 1.7 wt%, the microhardness of the material increased from 296HV to 452 HV, which is comparable to the microhardness of high-manganese steel. Finally, the thermodynamic parameter Φ was calculated using a phase prediction package AlloyASAP, allowing to establish that boron addition to Fe 50 Mn 30 Co 10 Cr 10 originated medium-entropy alloys (Φ   1).
Anthropometric analysis of maxillary anterior buccal bone of Korean adults using cone-beam CT

PURPOSE
The aim of this study was to evaluate the thickness of buccal and palatal alveolar bone and buccal bony curvature below root apex in maxillary anterior teeth of Korean adults using Cone-beam CT images.


MATERIALS AND METHODS
The 3D image was reconstructed with dicom file obtained through CBCT from 20 - 39 year old Korean subjects (n = 20). The thickness of buccal and palatal plate, root diameter, the buccal bony curvature angle below root apex and the distance from root apex to the deepest point of buccal bony curvature were measured on maxillary anterior teeth area using OnDemand3D program.


RESULTS
Mean thickness of buccal plate 3 mm below CEJ was 0.68 ± 0.29 mm at central incisor, 0.76 ± 0.59 mm at lateral incisor, and 1.07 ± 0.80 mm at canine. Mean thickness of palatal plate 3 mm below CEJ was 1.53 ± 0.55 mm of central incisor, 1.18 ± 0.66 mm of lateral incisor, 1.42 ± 0.77 mm of canine. Bucco-lingual diameter 3 mm below CEJ was 5.13 ± 0.37 mm of central incisor, 4.58 ± 0.46 mm of lateral incisor, and 5.93 ± 0.47 mm of canine. Buccal bony curvature angle below root apex was 134.7 ± 17.5° at central incisor, 151.0 ± 13.9° at lateral incisor, 153.0 ± 9.5° at canine. Distance between root apex and the deepest point of buccal bony curvature of central incisor was 3.67 ± 1.28 mm at central incisor, 3.90 ± 1.51 mm at lateral incisor, and 5.13 ± 1.70 mm at canine.


CONCLUSION
Within the limitation of this study in Korean adults, the thickness of maxillary anterior buccal plate was very thin within 1mm and the thickness of palatal plate was thick, relatively. The buccal bony curvature below root apex of maxillary central incisor was higher than that of lateral incisor and canine and it seems that the buccal bony plate below root apex of central incisor is most curved.
Behçet's syndrome patients have high levels of functional disability, fatigue and pain as measured by a Multi-dimensional Health Assessment Questionnaire (MDHAQ).

OBJECTIVE
Current tools for assessing Behçet's syndrome (BS) do not include patient-reported outcomes such as functional disability, pain or fatigue. We examined various outcome measures using the multi-dimensional Health Assessment Questionnaire (MDHAQ) and compared them between BS patients with and without arthritis. We also compared the results to those for patients with rheumatoid arthritis (RA), the disease in relation to which the MDHAQ has been most thoroughly studied.


METHODS
We conducted a comparative review of BS and early RA patients being followed at the New York University Hospital for Joint Diseases (NYU HJD) and the Behçet's Syndrome Center. All patients completed an MDHAQ at each visit, which included functional disability, pain, morning stiffness, fatigue, and patient and physician global assessments of disease activity. A chart review for BS manifestations and treatments was also carried out. All patient evaluations reported here represent the baseline values at first visit.


RESULTS
129 patients with BS and 116 with early RA were surveyed. BS patients had similar pain levels and physician global assessment of disease activity to the RA patients and higher functional disability, fatigue and patient assessments of global disease activity. Among BS patients, those with arthritis had significantly higher scores for all the outcome measures examined except the physician global assessment of disease activity.


CONCLUSION
Using the MDHAQ could reveal previously under-recognized problems in BS, as was observed in this survey of BS patients with arthritis. Such information might be helpful in the management of patients with BS.
Intake of antioxidants and risk of type 2 diabetes in a cohort of male smokers

Background/Objectives:Oxidative stress may induce insulin resistance in peripheral tissues and impair insulin secretion from pancreatic β-cells. Antioxidants are suggested to decrease the risk of diabetes through reduction of oxidative stress. However, only a few studies exist on dietary antioxidants and the risk of type 2 diabetes. We investigated the association of dietary antioxidants with incident type 2 diabetes in the α-Tocopherol, β-Carotene Cancer Prevention Study cohort.Subject/Methods:The study cohort included 29 133 male smokers aged 50–69 years. During a median follow-up of 10.2 years 660 incident cases of diabetes were observed among the 25 505 men with a completed baseline food frequency questionnaire.Results:Dietary α-tocopherol, β-tocopherol and β-tocotrienol were positively associated with the risk of diabetes when adjusted for age and supplementation (relative risk (RR) 1.17 (95% confidence interval (CI) 0.91–1.51) P for trend 0.02; RR 1.31 (95% CI 1.02–1.68) P for trend 0.01; RR 1.28 (95% CI 1.00–1.63) P for trend 0.01, respectively), but the association disappeared after multivariate adjustment (RR 0.92 (95% CI 0.71–1.19) P for trend 0.97; RR 1.06 (95% CI 0.82–1.36) P for trend 0.48; RR 1.04 (95% CI 0.80–1.35) P for trend 0.46, respectively). Other tocopherols and tocotrienols as well as vitamin C, carotenoids, flavonols and flavones had no association with risk of diabetes.Conclusions:Dietary antioxidants were not associated with a decreased risk of incident diabetes in middle-aged male smokers.
Institutional Change and American Economic Growth

Part I. The Theory Developed: 1. A theory of institutional change: concepts and causes 2. The government, coercion, and the redistribution of income 3. A theory of institutional innovation: description, analogy, specification 4. Changes in the institutional environment: exogenous shifts and arrangemental innovation Part II. The Theory Applied: 5. Land policy and American agriculture 6. Organization and reorganization in the financial markets: savings and investment in the American economy, 1820-1950 7. Transportation developments and economic growth 8. Economies of scale, unsuccessful cartelization, and external costs: some sidelights on the growth of manufacturing in the United States 9. Institutional change in the service industries 9. The labor force: organization and education Part III. Conclusions: 11. The changing public-private mix 12. History and the analysis of arrangemental change: a look to the past with an eye to the future.
High Track Pitch Capability for HAMR Recording

Differences in the areal density capability limits for heat-assisted magnetic recording (HAMR) and conventional perpendicular magnetic recording (PMR) are explored using spinstand measurements and micromagnetic modeling. The written track curvature and the transition width are measured with a special technique that mitigates cross-track averaging effects due to finite read sensor width. Tracks written with HAMR heads are shown to have more curvature compared with those written with modern PMR writers. Both broadening and transition curvatures are present cross track, that can be described reasonably well using Landau–Lifshitz–Gilbert modeling and indicates the effective gradient profile dominates. However, as we get to the track edge, we see disagreement between the model and the experiment, which is not currently reconciled. The curvature and broadening effects appear to challenge not only the downtrack bit resolution during readback, but also the cross-track written width with increased linear density. We discuss different near field transducer (NFT) designs, and comparing narrow versus wide thermal profile NFT designs, we can see that track pitch appears to weakly optimize to a maximal cross-track gradient point. Experimental measurements of constant bit error rate for different linear and track densities indicate a significant opportunity for high track density recording using HAMR. The difference appears to be related to the ability for HAMR to address high track pitches with a minimal increase in risk of adjacent track interference compared with PMR. We revise NFT head-to-media spacing requirements when we attempt to account for interference effects.