LLukas22/scidocs huggingface dataset:
Randomised clinical trial: addition of alginate-antacid (Gaviscon Double Action) to proton pump inhibitor therapy in patients with breakthrough symptoms.

BACKGROUND
Symptomatic breakthrough in proton pump inhibitor (PPI)-treated gastro-oesophageal reflux disease (GERD) patients is a common problem with a range of underlying causes. The nonsystemic, raft-forming action of alginates may help resolve symptoms.


AIM
To assess alginate-antacid (Gaviscon Double Action, RB, Slough, UK) as add-on therapy to once-daily PPI for suppression of breakthrough reflux symptoms.


METHODS
In two randomised, double-blind studies (exploratory, n=52; confirmatory, n=262), patients taking standard-dose PPI who had breakthrough symptoms, assessed by Heartburn Reflux Dyspepsia Questionnaire (HRDQ), were randomised to add-on Gaviscon or placebo (20 mL after meals and bedtime). The exploratory study endpoint was change in HRDQ score during treatment vs run-in. The confirmatory study endpoint was "response" defined as ≥3 days reduction in the number of "bad" days (HRDQ [heartburn/regurgitation] >0.70) during treatment vs run-in.


RESULTS
In the exploratory study, significantly greater reductions in HRDQ scores (heartburn/regurgitation) were observed in the Gaviscon vs placebo (least squares mean difference [95% CI] -2.10 [-3.71 to -0.48]; P=.012). Post hoc "responder" analysis of the exploratory study also revealed significantly more Gaviscon patients (75%) achieved ≥3 days reduction in "bad" days vs placebo patients (36%), P=.005. In the confirmatory study, symptomatic improvement was observed with add-on Gaviscon (51%) but there was no significant difference in response vs placebo (48%) (OR (95% CI) 1.15 (0.69-1.91), P=.5939).


CONCLUSIONS
Adding Gaviscon to PPI reduced breakthrough GERD symptoms but a nearly equal response was observed for placebo. Response to intervention may vary according to whether symptoms are functional in origin.
Chemical gastric inhibitory polypeptide receptor antagonism protects against obesity, insulin resistance, glucose intolerance and associated disturbances in mice fed high-fat and cafeteria diets

Gastric inhibitory polypeptide (GIP) receptor antagonism with (Pro3)GIP improves glucose tolerance and ameliorates insulin resistance and abnormalities of islet structure/function in ob/ob mice. This study examined the ability of (Pro3)GIP to counter the development of obesity, insulin resistance and diabetes in mice fed high-fat and cafeteria diets. Young Swiss TO mice on standard chow or high-fat, cafeteria or high-carbohydrate diets received daily injections of either saline or (Pro3)GIP (25 nmol kg-1day-1) over 16 weeks. Food intake, body weight, and circulating glucose and insulin were measured frequently. At 16 weeks, glucose tolerance, insulin sensitivity, HbA1c, circulating hormones and plasma lipids were assessed. Adipose tissue, liver and muscle were excised and weighed, and their histology and triacylglycerol content were further examined. (Pro3)GIP significantly reduced body weight, enhanced locomotor activity, and improved HbA1c, glucose tolerance, beta cell responsiveness and insulin sensitivity in mice fed high-fat and cafeteria diets (p < 0.05 to p < 0.01). Similarly, (Pro3)GIP significantly reduced plasma corticosterone and triacylglycerols (p < 0.05 to p < 0.001), while glucagon, resistin and adiponectin were unchanged. (Pro3)GIP decreased adipose tissue mass (p < 0.01) and the triacylglycerol content of liver, muscle and adipose tissue (p < 0.01 to p < 0.001). Adipocyte size and liver morphology were partially normalised. (Pro3)GIP did not significantly affect any of these parameters in mice fed a high-carbohydrate diet. (Pro3)GIP protects against obesity, insulin resistance, glucose intolerance and associated disturbances in mice fed high-fat and cafeteria diets. This highlights chemical GIP receptor antagonism as a new possibility for the treatment of obesity and associated metabolic disturbances.
Lessons learned: a pilot study on occupational therapy effectiveness for children with sensory modulation disorder.

OBJECTIVE
The purpose of this pilot study was to prepare for a randomized controlled study of the effectiveness of occupational therapy using a sensory integration approach (OT-SI) with children who have sensory processing disorders (SPD).


METHOD
A one-group pretest, posttest design with 30 children was completed with a subset of children with SPD, those with sensory modulation disorder.


RESULTS
Lessons learned relate to (a) identifying a homogeneous sample with quantifiable inclusion criteria, (b) developing an intervention manual for study replication and a fidelity to treatment measure, (c) determining which outcomes are sensitive to change and relate to parents' priorities, and (d) clarifying rigorous methodologies (e.g., blinded examiners, randomization, power).


CONCLUSION
A comprehensive program of research is needed, including multiple pilot studies to develop enough knowledge that high-quality effectiveness research in occupational therapy can be completed. Previous effectiveness studies in OT-SI have been single projects not based on a unified long-term program of research.
Who uses Facebook? An investigation into the relationship between the Big Five, shyness, narcissism, loneliness, and Facebook usage

The unprecedented popularity of the social networking site Facebook raises a number of important questions regarding the impact it has on sociality. However, as Facebook is a very recent social phenomenon, there is a distinct lack of psychological theory relating to its use. While research has begun to identify the types of people who use Facebook, this line of investigation has been limited to student populations. The current study aimed to investigate how personality influences usage or non-usage of Facebook. The sample consisted of 1324 self-selected Australian Internet users (1158 Facebook users and 166 Facebook nonusers), between the ages of 18 and 44. Participants were required to complete an online questionnaire package comprising the Big Five Inventory (BFI), the Narcissistic Personality Inventory – 29-item version (NPI-29), the Revised Cheek and Buss Shyness Scale (RCBS), and the Social and Emotional Loneliness Scale for Adults – Short version (SELSA-S). Facebook users also completed a Facebook usage questionnaire. The results showed that Facebook users tend to be more extraverted and narcissistic, but less conscientious and socially lonely, than nonusers. Furthermore, frequency of Facebook use and preferences for specific features were also shown to vary as a result of certain characteristics, such as neuroticism, loneliness, shyness and narcissism. It is hoped that research in this area continues, and leads to the development of theory regarding the implications and gratifications of Facebook use. 2011 Elsevier Ltd. All rights reserved.
Fields and colors

We exhibit a simplified version of the construction of a field of Morley rank p with a predicate of rank p − 1, extracting the main ideas for our construction from previous papers and refining the arguments. Moreover, an explicit axiomatization is given and ranks are computed.
Preventive effect of greater occipital nerve block on severity and frequency of migraine headache.

BACKGROUND
Despite a favorable clinical experience, little evidence exists for the efficacy of greater occipital nerve block (GONB) in migraine treatment. Considering such a premise, we wished to evaluate the therapeutic efficacy of GONB in patients affected by migraine headaches.


METHODS
A randomized double-blinded controlled trial was conducted on 48 patients suffering from migraine headaches. A syringe containing 1.0 mL of lidocaine 2%, 0.5 mL of either saline (control group, N = 24) or triamcinolone 0.5 mL (intervention group, N = 24) was prepared for each patient. Patients were assessed prior to the injection, and also 2 weeks, 1 month, and 2 months thereafter for severity and frequency of pain, times to use analgesics and any appeared side effects.


RESULTS
No significant differences were revealed in pain severity, pain frequency, and analgesics use between the two groups at the four study time points including at baseline, and 2, 4, and 8 weeks after the intervention. However, in both groups, the indices of pain severity, pain frequency, and analgesics use were significantly reduced at the three time points after the intervention compared with before the intervention.


CONCLUSION
GONB with triamcinolone in combination with lidocaine or normal saline with lidocaine results in reducing pain severity and frequency as well as use of analgesics up to two months after the intervention, however any difference attributed to the drug regimens by assessing of the trend of pain characteristics changes.
The role of inter-channel trust transfer in establishing mobile commerce trust

Mobile brokerage services represent an emerging application of mobile commerce in the brokerage industry. Compared with telephone-based trading services and online brokerage services, they have advantages such as ubiquity, convenience, and privacy. However, the number of investors using mobile brokerage services to conduct brokerage transactions is far smaller than those using other trading methods. A plausible reason for this is that investors lack initial trust in mobile brokerage services, which affects their acceptance of them. This research examines trust transfer as a means of establishing initial trust in mobile brokerage services. We analyze how an investor’s trust in the online brokerage services of a brokerage firm affects her cognitive beliefs about the mobile brokerage services of the firm and what other key factors influence the formation of initial trust in mobile brokerage services. We develop and empirically test a theoretical model of trust transfer from the online to the mobile channels. Our results indicate that trust in online brokerage services not only has a direct effect on initial trust but also has an indirect effect through other variables. This study provides useful suggestions and implications for academics and practitioners. 2011 Elsevier B.V. All rights reserved.
Randomized, Prospective Comparison of Bioabsorbable and Steel Screw Fixation of Lisfranc Injuries.

OBJECTIVE
This study's objective is to compare outcomes of bioabsorbable versus steel screws for treating Lisfranc injuries.


DESIGN
This research was conducted in a prospective and randomized manner between September 2008 and December 2013.


SETTING
This study was performed in the outpatient setting at a tertiary-level care center in a single surgeon's practice.


PATIENTS/PARTICIPANTS
Forty patients with acute Lisfranc injuries, amenable to open reduction and screw fixation, enrolled and presented for final follow-up.


INTERVENTION
Through randomization, 20 and 20 patients received bioabsorbable versus steel screws, respectively.


OUTCOME MEASUREMENTS
Function and pain were graded using the Foot and Ankle Ability Measures (FAAM) and a visual analog scale of pain. Radiographs were assessed for joint stability and degeneration.


RESULTS
For those with steel screws, the mean FAAM score increased from 24.9 to 89.6 of 100 and pain score decreased from 6.5 to 1.9 of 10 by latest follow-up. For those with absorbable screws, the mean FAAM score increased from 32.5 to 91.2 and pain score decreased from 4.7 to 1.3 by latest follow-up. These differences in final mean function (P = 0.4) and pain (P = 0.25) between the study groups were not statistically significant. Final radiographs showed no Lisfranc instability in any study patients, but rather midfoot arthritis in 4 and 2 patients with steel versus bioabsorbable screws, respectively. None of the patients who received steel screws had hardware-related problems, but 1 patient who received absorbable fixation developed an inflammatory reaction at a nonresorbed screw head at 2 years after surgery.


CONCLUSIONS
Bioabsorbable screws provide short-term results that are comparable and not significantly different from steel screws for treating unstable Lisfranc injuries. Both methods are predictable in improving function and pain, but using absorbable screws eliminates the need for hardware removal after such trauma.


LEVEL OF EVIDENCE
Therapeutic Level I. See Instructions for Authors for a complete description of levels of evidence.
Changes of antioxidative enzymes, lipid peroxidation and chlorophyll content in chickpea types colonized by different Glomus species under drought stress

In order to investigate the effects of Glomus species on some physiological characteristics of two chickpea types (Pirouz cultivar of Desi type and ILC-482 of Kabuli type) under non-stress (NS) and drought stress, an experiment was conducted using a factorial arrangement based on completely randomized design with three replications. Drought stress decreased shoot and total dry weight in plants. However inoculation of plants with mycorrhiza improved these traits. Leaf chlorophyll content was decreased, but leaf proline content and guaiacol peroxidases (EC 1.11.1.7) (POD), catalase (EC 1.11.1.6) (CAT), and ascorbate peroxidase (EC 1.11.1.11) (APX) activities were increased as a result of drought stress. Drought stress had no significant effect on soluble protein content and polyphenol oxidase (EC 1.10.3.1) (PPO) enzymatic activity in chickpea plants. In general, drought stress and especially severe drought stress increased membrane lipid peroxidation (MDA) in chickpea plants, which was more evident in non-inoculated than in inoculated plants. Inoculation of chickpea by AM significantly increased POD and PPO activities compared with non-inoculated chickpea, but had no effect on CAT activity and proline content of leaves. The reaction of chickpea cultivars to inoculation by AM species and irrigation levels were different. ILC-482 showed that antioxidant enzymes activities were more and thus less MDA compared with Pirouz cultivar. In general, the most POD and PPO activities were recorded for inoculated plants with G. etunicatum and G. versiform species, and the most APX activity was observed in plants inoculated with G. intraradices.
Bridgeless PFC implementation using one cycle control technique

Conventional boost PFC suffers from the high conduction loss in the input rectifier-bridge. Higher efficiency can be achieved by using the bridgeless boost topology. This new circuit has issues such as voltage sensing, current sensing and EMI noise. In this paper, one cycle control technique is used to solve the issues of the voltage sensing and current sensing. Experimental results show efficiency improvement and EMI performance
Use of External Visual Representations in Probability Problem Solving.

We investigate the use of external visual representations in probability problem solving. Twenty-six students enrolled in an introductory statistics course for social sciences graduate students (post-baccalaureate) solved eight probability problems in a structured interview format. Results show that students spontaneously use selfgenerated external visual representations while solving probability problems. The types of visual representations used include: reorganization of the given information, pictures, novel schematic representations, trees, outcome listings, contingency tables, and Venn diagrams. The frequency of use of each of these different external visual representations depended on the type of probability problem being solved. We interpret these findings as showing that problem solvers attempt to select representations appropriate to the problem structure, and that the appropriateness of the representation is determined by the problem’s underlying schema.
Revisiting Bertin Matrices: New Interactions for Crafting Tabular Visualizations

We present Bertifier, a web app for rapidly creating tabular visualizations from spreadsheets. Bertifier draws from Jacques Bertin's matrix analysis method, whose goal was to “simplify without destroying” by encoding cell values visually and grouping similar rows and columns. Although there were several attempts to bring this method to computers, no implementation exists today that is both exhaustive and accessible to a large audience. Bertifier remains faithful to Bertin's method while leveraging the power of today's interactive computers. Tables are formatted and manipulated through crossets, a new interaction technique for rapidly applying operations on rows and columns. We also introduce visual reordering, a semi-interactive reordering approach that lets users apply and tune automatic reordering algorithms in a WYSIWYG manner. Sessions with eight users from different backgrounds suggest that Bertifier has the potential to bring Bertin's method to a wider audience of both technical and non-technical users, and empower them with data analysis and communication tools that were so far only accessible to a handful of specialists.COMPUTER
A planar microstrip-line fed elliptical UWB 5.2 GHz/5.8 GHz notch antenna with U-shaped slot

A planar ultrawideband (UWB) monopole antenna with an U-shaped slot is etched in the radiating patch for the 5.2/5.8 GHz band-notched function is presented. The proposed antenna has an elliptical radiating patch with a U-shaped slot is removed from the patch. The structure provides a wide fractional bandwidth of more then 115 percent (2.76–17.68 GHz) except in the frequency band range of 5.2 GHz to 5.8 GHz, which is the operating frequency range of Wireless Local Area Network (WLAN). A 50-ohm microstrip-line is used to feed the antenna. The proposed antenna is simple and compact in size providing broadband impedance matching, consistent radiation pattern appropriate gain characteristics within the UWB frequency range.
Meta-analysis of scientometric research of knowledge management: discovering the identity of the discipline

Purpose – The purpose of this study is to conduct a meta-analysis of prior scientometric research of the knowledge management (KM) field. Design/methodology/approach – A total of 108 scientometric studies of the KM discipline were subjected to meta-analysis techniques. Findings – The overall volume of scientometric KM works has been growing, reaching up to ten publications per year by 2012, but their key findings are somewhat inconsistent. Most scientometric KM research is published in non-KM-centric journals. The KM discipline has deep historical roots. It suffers from a high degree of over-differentiation and is represented by dissimilar research streams. The top six most productive countries for KM research are the USA, the UK, Canada, Germany, Australia, and Spain. KM exhibits attributes of a healthy academic domain with no apparent anomalies and is progressing towards academic maturity. Practical implications – Scientometric KM researchers should use advanced empirical methods, become aware of prior scientometric research, rely on multiple databases, develop a KM keyword classification scheme, publish their research in KM-centric outlets, focus on rigorous research of the forums for KM publications, improve their cooperation, conduct a comprehensive study of individual and institutional productivity, and investigate interdisciplinary collaboration. KM-centric journals should encourage authors to employ under-represented empirical methods and conduct meta-analysis studies and should discourage conceptual publications, especially the development of new frameworks. To improve the impact of KM research on the state of practice, knowledge dissemination channels should be developed. Originality/value – This is the first documented attempt to conduct a meta-analysis of scientometric research of the KM discipline.
Comparing Word Representations for Implicit Discourse Relation Classification

This paper presents a detailed comparative framework for assessing the usefulness of unsupervised word representations for identifying so-called implicit discourse relations. Specifically, we compare standard one-hot word pair representations against low-dimensional ones based on Brown clusters and word embeddings. We also consider various word vector combination schemes for deriving discourse segment representations from word vectors, and compare representations based either on all words or limited to head words. Our main finding is that denser representations systematically outperform sparser ones and give state-of-the-art performance or above without the need for additional hand-crafted features.
How to model and augment player satisfaction: a review

This is a review on approaches for modeling satisfaction perceived by users interacting with entertainment systems. Experimental studies with adult and children users of games (screen-based and physical-interactive) are outlined and the most promising approaches for augmenting player satisfaction while the game is played (i.e. in real-time) are discussed.
Enhancing cognitive-behavioural therapy for recurrent headache: design of a randomised controlled trial

BACKGROUND
We have argued against the traditional approach of counselling avoidance of all triggers of headaches and migraine. Problems with this approach include the impossibility of avoiding all triggers and the high costs associated with trying to do so, and that avoidance could lead to reduced tolerance for the triggers. We have developed an alternative approach called Learning to Cope with Triggers (LCT) that encourages avoidance of triggers that are detrimental to health and wellbeing, but uses exposure to other triggers to desensitise headache sufferers to the triggers. This approach has been shown to be more effective than advising avoidance of all triggers. Trigger management is only one component of a comprehensive treatment program and the current study is designed to evaluate a new approach to treating headaches in which LCT has been integrated into an established cognitive-behavioural therapy (CBT) package (LCT/CBT).


METHODS/DESIGN
A target sample of 120 adult participants who suffer from migraine or tension-type headache, at least six days per month, and have done so for at least 12 months will be recruited. Participants will be randomly assigned to one of three groups: LCT/CBT; Avoid/CBT (CBT combined with instructions to avoid all triggers); and waiting-list control. Measures will include: daily diaries for recording headaches, triggers and medication consumption; headache disability and quality of life; trigger avoidance; locus of control and self-efficacy; and coping strategies. Treatment will involve 12 60-minute sessions scheduled weekly. Assessment will be completed before and after treatment, and at 4 and 12 month follow-up. The data will be analysed to determine which approach is most effective, and predictors of response to treatment.


DISCUSSION
Migraine and tension-type headache are common and can be disabling. CBT has been demonstrated to be an efficacious treatment for both disorders. However, there is room for improvement. This study aims to increase the efficacy of behavioural approaches and identify factors predictive of a positive response.


TRIAL REGISTRATION
Australian and New Zealand Clinical Trials Registry ACTRN12614000435684 .