LLukas22/scidocs huggingface dataset:
Spanish Catheter Ablation Registry. 9th Report of the Spanish Society Of Cardiology Working Group on Electrophysiology and Arrhythmias (2009).

INTRODUCTION AND OBJECTIVES
This article reports the findings of the 2009 Spanish national Catheter Ablation Registry.


METHODS
Data were collected in two ways: retrospectively using a standard questionnaire and prospectively from a central database. Each center chose its own preferred method of data collection.


RESULTS
Data were collected from 59 centers. The total number of ablation procedures carried out was 8546, giving a mean of 145 ± 101 procedures per center. The three most frequently treated conditions were atrioventricular nodal reentrant tachycardia (n = 2341; 27%), typical atrial flutter (n = 1859; 21.7%) and accessory pathways (n = 1758; 20.5%). The fourth most common condition was atrial fibrillation (n = 1188; 14%), the number of which has grown by 44% since the 2008 registry. The overall success rate was 93%, major complications occurred in 1.9%, and the mortality rate was 0.046%.


CONCLUSIONS
Data from the 2009 registry show that the number of ablations carried out continued to increase and exceeded 8000 for the first time. In addition, they show, in general, a higher success rate and a lower number of complications. Cavotricuspid isthmus ablation, as treatment for typical atrial flutter, continued to be the second most common procedure. There was a substantial increase in the number of catheter ablations performed for atrial fibrillation compared with previous years.
Gossip training for deep learning

We address the issue of speeding up the training of convolutional networks. Here we study a distributed method adapted to stochastic gradient descent (SGD). The parallel optimization setup uses several threads, each applying individual gradient descents on a local variable. We propose a new way to share information between different threads inspired by gossip algorithms and showing good consensus convergence properties. Our method called GoSGD has the advantage to be fully asynchronous and decentralized. We compared our method to the recent EASGD in [17] on CIFAR-10 show encouraging results.
Immunopathology of atopic dermatitis

In summary, AD is a chronic inflammatory skin disease associated with increased IgE production, eosinophilia, increased mast cell number and increased expression of the CD23 low-affinity IgE receptor on mononuclear cells. The basis of these immunologic defects appear to be the result of increased numbers of IL-4-, IL-5-producing Th2 cells. This results in an overstimulation of their IL-4-IL-4 receptor pathway that is accompanied by a relative deficiency of IFN-γ production. The acute manifestations of AD occur as the result of mast cell degranulation that can be triggered by a variety of stimuli including allergens, bacterial toxins or histamine-releasing factors secreted by activated T cells and macrophages. Mast cells release not only histamine which contributes to the acute sensation of pruritus but also cytokines and chemotactic factors which induce leukocyte adhesion molecules and attract inflammatory cells into the local tissue sites [3, 8, 26, 34]. The chronic manifestations of AD are probably the result of sustained cellular activation. The cellular infiltrate in the chronic lesion of AD consists primarily of T cells and macrophages [29]. T lymphocytes play two important roles in allergic responses: First, as already discussed they play a critical role in the regulation of IgE responses. Second, there is increasing evidence that they may play an important role in the control of the inflammatory response. This is orchestrated through organization of the cellular composition of the inflammatory cell infiltrate by the release of various cytokines. The release of IL-3, IL-5, and GM-CSF have pronounced effects on the differentiation and activation of eosinophils [52]. IL-3 promotes the growth of mucosal mast cells and stimulates basophil and mast cell histamine release. IL-4 promotes the growth of murine mast cells [18] and induces the expression of CD23 on macrophages [71]. The release of cytokines may, thus, account for the observation of increased mast cell number in chronic eczematoid lesions. Taken together, these observations suggest that the AD skin lesion is characterized by the infiltration of inflammatory cells which differ from those infiltrating into a type IV contact-sensitivity reaction. The sustained immune activation, which results in chronic AD, may be the result of an underlying T cell defect, e.g., decreased IFN-γ production following the activation of lymphocytes with a variety of stimuli. Treatment of patients withh rIFN-γ down-regulates the IL-4-IL-4 receptor pathway which is overstimulated in this disease. It is important to note, however, that although many immunopathologic features of AD have recently been elucidated, the fundamental etiology of these abnormalities remains to be unraveled.
Is Circumferential Minimally Invasive Surgery Effective in the Treatment of Moderate Adult Idiopathic Scoliosis?

BACKGROUND
Outcomes for minimally invasive scoliosis correction surgery have been reported for mild adult scoliosis. Larger curves historically have been treated with open surgical procedures including facet resections or posterior column osteotomies, which have been associated with high-volume blood loss. Further, minimally invasive techniques have been largely reported in the setting of degenerative scoliosis.


QUESTIONS/PURPOSES
We describe the effects of circumferential minimally invasive surgery (cMIS) for moderate to severe scoliosis in terms of (1) operative time and blood loss, (2) overall health and disease-specific patient-reported outcomes, (3) deformity correction and fusion rate, and (4) frequency and types of complications.


METHODS
Between January 2007 and January 2012, we performed 50 cMIS adult idiopathic scoliosis corrections in patients with a Cobb angle of greater than 30° but less than 75° who did not have prior thoracolumbar fusion surgery; this series represented all patients we treated surgically during that time meeting those indications. Our general indications for this approach during that period were increasing back pain unresponsive to nonoperative therapy with cosmetic and radiographic worsening of curves. Surgical times and estimated blood loss were recorded. Functional clinical outcomes including VAS pain score, Oswestry Disability Index (ODI), and SF-36 were recorded preoperatively and postoperatively. Patients' deformity correction was assessed on pre- and postoperative 36-inch (91-cm) standing films and fusion was assessed on CT scan. Minimum followup was 24 months (mean, 48 months; range, 24-77 months).


RESULTS
Mean blood loss was 613 mL for one-stage surgery and 763 mL for two-stage surgery. Mean operative time was 351 minutes for one-stage surgery and 482 minutes for two-stage surgery. At last followup, mean VAS and ODI scores decreased from 5.7 and 44 preoperatively to 2.9 and 22 (p < 0.001 and 0.03, respectively) and mean SF-36 score increased from 48 preoperatively to 74 (p = 0.026). Mean Cobb angle and sagittal vertical axis decreased from 42° and 51 mm preoperatively to 16° and 27 mm postoperatively (both p < 0.001). An 88% fusion rate was confirmed on CT scan. Perioperative complications occurred in 11 of the 50 patients (22%), with delayed complications needing further surgery in 10 more patients at last followup.


CONCLUSIONS
cMIS provides for good clinical and radiographic outcomes for moderate (30°-75°) adult idiopathic scoliosis. Patients undergoing cMIS should be carefully selected to avoid fixed, rigid deformities and a preoperative sagittal vertical axis of greater than 10 cm; surgeons should consider alternative techniques in those patients.


LEVEL OF EVIDENCE
Level IV, therapeutic study. See Instructions for Authors for a complete description of levels of evidence.
Meeting the challenges of training more medical students: lessons from Flinders University's distributed medical education program.

OBJECTIVE
To use data from an evaluation of the Flinders University Parallel Rural Community Curriculum (PRCC) to inform four immediate challenges facing medical education in Australia as medical student numbers increase.


DESIGN, SETTING AND PARTICIPANTS
Thematic analysis of data obtained from focus groups with medical students undertaking the PRCC, a year-long undergraduate clinical curriculum based in rural general practice; and individual interviews with key faculty members, clinicians, health service managers and community representatives from 13 rural general practices and one urban tertiary teaching hospital in South Australia. Data were collected in 2006 and re-analysed for this study in January 2009.


MAIN OUTCOME MEASURES
Participants' views grouped around the themes of the four identified challenges: how to expand the venues for clinical training without compromising the quality of clinical education; how to encourage graduates to practise in under-served rural, remote and outer metropolitan regions; how to engage in a sustainable way with teaching in the private sector; and how to reverse the current decline in altruism and humanism in medical students during medical school.


RESULTS
Participants' views supported the PRCC approach as a solution to the challenges facing Australian medical education. The enabling capacity of the PRCC's longitudinal integrated approach to clinical attachments was revealed as a key factor that was common to each of the four themes.


CONCLUSIONS
The continuity provided by longitudinal integrated clinical attachments enables an expansion of clinical training sites, including into primary care and the private sector. This approach to clinical training also enables students to develop the skills and personal qualities required to practise in areas of need.
T-LEACH: The method of threshold-based cluster head replacement for wireless sensor networks

In wireless sensor networks, power is the most essential resource because each sensor node has limited batteries. Many kinds of existing clustering protocols have been developed to balance and maximize lifetime of the sensor nodes in wireless sensor networks. These protocols select cluster heads periodically, and they considered only ‘How can we select cluster heads energy-efficiently?’ or ‘What is the best selection of cluster heads?’ without considering energy-efficient period of the cluster heads replacement. Unnecessary head selection may dissipate limited battery power of the entire sensor networks. In this paper, we present T-LEACH, which is a threshold-based cluster head replacement scheme for clustering protocols of wireless sensor networks. T-LEACH minimizes the number of cluster head selection by using threshold of residual energy. Reducing the amount of head selection and replacement cost, the lifetime of the entire networks can be extended compared with the existing clustering protocols. Our simulation results show that T-LEACH outperformed LEACH in terms of balancing energy consumption and network lifetime.
The Mycology as Forensics Tool

Volume 5 • Issue 2 • 1000226 Adv Tech Biol Med, an open access journal ISSN: 2379-1764 The main focus of the forensic taphonomy is the study of environmental conditions influencing the decomposition process to estimate the postmortem interval and determine the cause and manner of death. The study is part of a specific branch of the forensic science that makes use of a broad aspect of methodologies taken from different areas of expertise such as botany, archeology, soil microbiology and entomology, all used for uncovering and examining clandestine graves allowing to succeed in the investigation process. Therefore, the “Forensic Mycology” emerges as a new science term meaning the study of the coexistence of fungal species nearby human cadavers as well as those fungal groups potentially useful in establishing a time of death [1,2].
A data model of theses and dissertations compatible with CERIF, Dublin Core and EDT-MS

Purpose – The aim of this research is to define a data model of theses and dissertations that enables data exchange with CERIF-compatible CRIS systems and data exchange according to OAI-PMH protocol in different metadata formats (Dublin Core, EDT-MS, etc.). Design/methodology/approach – Various systems that contain metadata about theses and dissertations are analyzed. There are different standards and protocols that enable the interoperability of those systems: CERIF standard, AOI-PMH protocol, etc. A physical data model that enables interoperability with almost all of those systems is created using the PowerDesigner CASE tool. Findings – A set of metadata about theses and dissertations that contain all the metadata required by CERIF data model, Dublin Core format, EDT-MS format and all the metadata prescribed by the University of Novi Sad is defined. Defined metadata can be stored in the CERIF-compatible data model based on the MARC21 format. Practical implications – CRIS-UNS is a CRIS which has been developed at the University of Novi Sad since 2008. The system is based on the proposed data model, which enables the system’s interoperability with other CERIF-compatible CRIS systems. Also, the system based on the proposed model can become a member of NDLTD. Social implications – A system based on the proposed model increases the availability of theses and dissertations, and thus encourages the development of the knowledge-based society. Originality/value – A data model of theses and dissertations that enables interoperability with CERIF-compatible CRIS systems is proposed. A software system based on the proposed model could become a member of NDLTD and exchange metadata with institutional repositories. The proposed model increases the availability of theses and dissertations.
Does artificial UV use prior to spring break protect students from sunburns during spring break?

BACKGROUND
Dark-skinned individuals are less likely than light-skinned individuals to become sunburned or develop skin cancer. Some have extrapolated this relationship and surmised that developing and maintaining a tan will reduce the risk of sunburns and melanoma. In order to examine whether this strategy indeed protects against sunburns, we surveyed college students about both their tanning habits prior to spring break and their spring break activities.


METHODS
Sorority and fraternity students were recruited after spring break. Analyses examined associations between potential risk factors and the development of one or more sunburns during spring break.


RESULTS
As expected, the risk of obtaining a sunburn increased with: time spent in the sun during spring break; light complexion, as assessed by various sun-sensitivity factors; and lack of sunscreen use. We also found that tanning using an artificial UV source during the 10 weeks prior to spring break was not associated with reduced risk of sunburns during spring-break, but rather with a marginal increase in this risk.


CONCLUSIONS
These data provide evidence that maintaining a tan may not provide protection from sunburns. Public health messages need to address this misconception, stating clearly that a tan does not protect against or reduce the chances of developing a sunburn.
Atomic scale investigation of ordering and precipitation processes in a model NiCrAl alloy

Abstract The tomographic atom probe has been applied to the study of early stages of precipitation of the Ni 3 Al-type ordered γ′ phase in a model nickel base superalloy NiCrAl. The investigation of a low-supersaturated alloy (15 at% Cr, 5 at% Al) aged at 600°C shows that small γ′ particles 2 nm in diameter form already after 1 h. Even for such very small sizes, particles are well ordered. Their composition is close to the equilibrium composition of the γ′ phase and does not evolve as ageing proceeds. The time evolution of the particle size and of the composition of the γ matrix suggests that a growth mechanism is involved before 4 h, followed by a coarsening regime.
Classification of chronic obstructive pulmonary disease severity according to the new Global Initiative for Chronic Obstructive Lung Disease 2011 guidelines: COPD assessment test versus modified Medical Research Council scale.

INTRODUCTION
The GOLD2011 revision proposes to stratify patients with chronic obstructive pulmonary disease (COPD) by measuring the impact of the disease using the modified Medical Research Council (mMRC) scale or COPD assessment test (CAT). Our aim was to determine whether both methods are equivalent.


PATIENTS AND METHODS
Observational study on a cohort of 283 patients diagnosed with COPD. We analyzed the demographic and lung function results. Patients were assessed by CAT and mMRC on the same day by the same interviewer, and divided into GOLD2011 categories according to the result of the evaluation. The degree of concordance and Spearman correlation were determined. We used ANOVA on the clinical and functional variables of the four GOLD2011 categories.


RESULTS
Assessing the classification of patients according to the method used, an overall correlation ρ=0.613 and a degree of concordance κ=0.63 (moderate) were obtained. κ=0.44 was obtained for the 152 patients in categoriesA and B (moderate-low), and 0.38 for the 131 patients in categoriesC and D (low). Differences were observed between categories in terms of functional parameters.


CONCLUSIONS
The classification of patients with COPD using the assessment proposed by GOLD2011 varies according to the method used (CAT or mMRC); more than 25% of patients were reclassified into different categories, implying differences in the recommended therapeutic strategy. Longitudinal studies are needed to appraise which method better classifies patients, according to its prognostic ability.
An Analysis of Relationship between Total Quality Management and Kaizen

Total Quality Management (TQM) and Kaizena continuous change toward betterment are two fundamental concepts directly dealing with continuous improvement of quality of processes and performance of an organization to achieve positive transformation in mindset and action of employees and management. For clear understanding and to get maximum benefit from both of these concepts, as such it becomes mandatory to precisely differentiate between TQM and Kaizen. TQM features primarily focus on customer’s satisfaction through improvement of quality. It is both a top down and bottom up approach whereas kaizen is processes focused and a bottom up approach of small incremental changes. Implementation of TQM is more costly as compared to Kaizen. Through kaizen, improvements are made using organization’s available resources. For the effective implementation of kaizen, the culture of the organization must be supportive and the result of continuous improvement should be communicated to the whole organization for motivation of all employees and for the success of continuous improvement program in the organization. This paper focuses on analyzing the minute differences between TQM and Kaizen. It also discusses the different tools and techniques under the umbrella of kaizen and TQM Philosophy. This paper will elucidate the differences in both these concepts as far as their inherent characteristics and practical implementations are concerned. In spite of differences in methodology, focus and scale of operation in both the concept, it can be simply concluded that Kaizen is one of the Technique of the T QM for continuous improvement of quality, process and performance of the organization. [Muhammad Saleem, Nawar Khan, Shafqat Hameed, M Abbas Ch. An Analysis of Relationship between Total Quality Management and Kaizen. Life Science Journal. 2012;9(3):31-40] (ISSN:1097-8135). http://www.lifesciencesite.com. 5 Key Worlds: Total Quality Management, Kaizen Technique, Continuous Improvement (CI), Tools & Techniques
Reweighted Random Walks for Graph Matching

 Random walks on an association graph using candidate matches as nodes. Rank candidate matches by stationary distribution  Personalized jump for enforcing the matching constraints during the random walks process  Matching constraints satisfying reweighting vector is calculated iteratively by inflation and bistochastic normalization  Due to object motion or viewpoint change, relationships between two nodes are not exactly same Outlier Noise Deformation Noise
The effect of dietary vitamin E supply and a moderately oxidized oil on activities of hepatic lipogenic enzymes in rats

Diets rich in polyunsaturated fatty acids (PUFA) are well known to suppress hepatic lipogenic enzymes compared to fat-free diets or diets rich in saturated fatty acids. However, the mechanism underlying suppression of lipogenic enzymes is not quite clear. The present study was undertaken to investigate whether lipid peroxidation products are involved in suppression of lipogenic enzymes. Therefore, an experiment with growing male rats assigned to six groups over a period of 40 d was carried out. Rats received semisynthetic diets containing 9.5% coconut oil and 0.5% fresh soybean oil (coconut oil diet, peroxide value 5.1 meq O2/kg oil), 10% fresh soybean oil (fresh soybean oil diet, peroxide value 0.5 meq O2/kg oil), or 10% thermally treated soybean oil (oxidized soybean oil diet, peroxide value 74 meq O2/kg oil). To modify the antioxidant state of the rats, we varied the vitamin E supply (11 and 511 mg α-tocopherol equivalents per kg of diet) according to a bi-factorial design. Food intake and body weight gain were not influenced by dietary fat and vitamin E supply. Activities of hepatic lipogenic enzymes were markedly influenced by the dietary fat. Feeding either fresh or oxidized soybean oil diets markedly reduced activities of fatty acid synthase, (FAS), acetyl CoA-carboxylase, (AcCX), glucose-6-phosphate dehydrogenase, (G6PDH), 6-phosphogluconate dehydrogenase, and ATP citrate lyase (ACL) relative to feeding the coconut oil diet. Moreover, feeding oxidized soybean oil slightly, but significantly, lowered activities of FAS, AcCX, and ACL compared to feeding fresh soybean oil. Activities of hepatic lipogenic enzymes were reflected by concentrations of triglycerides in liver and plasma. Rats fed the coconut oil diet had markedly higher triglyceride concentrations in liver and plasma than rats consuming fresh or oxidized soybean oil diets, and rats fed oxidized soybean oil had lower concentrations than rats fed fresh soybean oil. The vitamin E supply of the rats markedly influenced concentrations of thiobarbituric acid-reactive substances in liver, but it did not influence activities of hepatic lipogenic enzymes. Because the vitamin E supply had no effect, and ingestion of an oxidized oil had only a minor effect, on activities of hepatic lipogenic enzymes, it is strongly suggested that neither exogenous nor endogenous lipid peroxidation products play a significant role in the suppression of hepatic lipogenic enzymes by diets rich in PUFA. Therefore, we assumed that dietary PUFA themselves are involved in regulatio of hepatic lipogenic enzymes. Nevertheless, the study shows that ingestion of oxidized oils, regardless of the vitamin E supply, also affects hepatic lipogenesis, and hence influences triglyceride levels in liver and plasma.