LLukas22/scidocs huggingface dataset:
Rewarding the work of individuals: a counterintuitive approach to reducing poverty and strengthening families.

Gordon Berlin discusses the nation's long struggle to reduce poverty in families with children, and proposes a counterintuitive solution--rewarding the work of individuals.He notes that policymakers' difficulty in reducing family poverty since 1973 is attributable to two intertwined problems--falling wages among low-skilled workers and the striking increase in children living with a lone parent, usually the mother. As the wages of men with a high school education or less began to decline, their employment rates did likewise. The share of men who could support a family above the poverty line thus began to decline--and with it the willingness of low-income women to marry the fathers of their children. Because the U.S. social welfare system is built around the needs of poor families with children--and largely excludes single adults who are poor (and disproportionately male)--it creates disincentives to work and marry for some families, aggravating these larger trends. Berlin proposes a new policy that would partially overcome the low wages and income of poorly educated males and second earners in two-parent households by using the earned income tax credit (EITC) to supplement the earnings of all low-wage workers aged twenty-one to fifty-four who work full time--regardless of whether they have children or whether they are married. By conditioning the benefit on full-time work and by retaining the existing family-based EITC program while treating EITC payments as individual income rather than as joint income for income tax purposes, the policy would restore equity to the American social compact without distorting incentives to work, marry, and bear children. The largest benefits by far would accrue to two-parent households in which both adults can work full time. Because the policy would carry a large price tag--nearly $30 billion a year when fully implemented--Berlin says that a prudent next step would be to test this strategy rigorously in several states over several years, preferably using a random assignment design.
Solving Circuit Optimisation Problems in Cryptography and Cryptanalysis

One of the hardest problems in computer science is the problem of gate-efficient implementation. Such optimizations are particularly important in industrial hardware implementations of standard cryptographic algorithms [13, 17, 7, 22]. In this paper we focus on optimizing some small circuits such as S-boxes in cryptographic algorithms. We consider the notion of Multiplicative Complexity, a new important notion of complexity studied in 2008 by Boyar and Peralta and applied to find interesting optimizations for the S-box of the AES cipher [19, 22, 21]. We applied this methodology to produce a compact implementation of several ciphers. In this short paper we report our results on PRESENT and GOST, two block ciphers known for their exceptionally low hardware cost. This kind of representation seems to be very promising in implementations aiming at preventing side channel attacks on cryptographic chips such as DPA. More importantly, we postulate that this kind of minimality is also an important and interesting tool in cryptanalysis.
Violent and nonviolent suicide in veterans with substance-use disorders.

OBJECTIVE
Substance-use disorders (SUDs) increase the risk of suicide. Examining risk factors for violent or nonviolent suicide in those with SUDs could improve suicide-prevention efforts in these individuals. We examined the demographic and clinical predictors of violent and nonviolent suicide among patients with SUDs.


METHOD
This study examined Veterans Affairs (VA) patients with SUDs who were alive at the beginning of Fiscal Year (FY) 2002 and died by suicide during FYs 2002 through 2006 (n = 854) and a random sample of 4,228 SUD patients who did not die by suicide during this period. Data were obtained from VA medical records and the National Death Index. Patients were considered to have an SUD if they received two or more diagnoses of the same SUD from FY 1997 to FY 2001.


RESULTS
Of those who died by suicide, 70% (n = 600) used violent means. Diagnoses of depressive, other anxiety, bipolar and posttraumatic stress disorders, schizophrenia, and personality disorders were associated with increased risk of both violent and nonviolent suicide; however, these associations were stronger for nonviolent than violent suicide deaths. Risk of nonviolent suicide was greater among patients with opioid-use disorders or a clinical diagnosis of abuse or dependence (according to the International Classification of Diseases, Tenth Revision) on multiple substances.


CONCLUSIONS
Most VA patients with SUDs who died from suicide used violent means. No specific SUD was associated with increased risk of violent suicide, but several SUD diagnoses were associated with increased risk of nonviolent suicide. Concurrent psychopathology increased risk for both suicide types; however, the relationship was strongest for nonviolent suicide.
Motion control technique for practical use of a leg-wheel robot on unknown outdoor rough terrains

In this paper, we propose a basic control method for the leg-wheel robot moving on unexplored rough terrains. When moving on a rough terrain, the compliance values and the trajectories of legs are set up according to the environment without using external sensors. And the step axis mechanism that we have developed, realizes the stable rolling movement of the robot. The proposed method is evaluated by a walking experiment in an outdoor natural terrain.
A Survey of Public Auditing for Shared Data Storage with User Revocation in Cloud Computing

Cloud computing technology has matured, so cloud computing produces a wide range of cloud service. Cloud storage services are one of cloud services where cloud service provider can provide storage space to customers. Because cloud storage services bring a lot of convenience, many enterprises and users store the data to the cloud storage. However, the user will outsource data to the cloud storage service, but the user is difficult to manage remote data in the cloud. Therefore, how users verify data integrity is a major challenge. In recent years, public audit is used to verify data integrity by which the user allows other to verify the user’s data. Because the feature of cloud service allows users to communicate with each other on the cloud platform, the cloud storage service allows the data owner to share their data to other users. Therefore, public auditing extends to the share data, so the original operation becomes not the same including signature, public audits, dynamic data and user revocation which generates on the situation of shared data. In the paper, we define the requirements of public auditing with shared data and explain four representative approaches which include analysis function, security, and performance requirements. Finally, we provide some topics for future research.
9 Chapter Nine Mobile Augmented Reality

As computers increase in power and decrease in size, new mobile, wearable, and pervasive computing applications are rapidly becoming feasible, providing people access to online resources always and everywhere. This new flexibility makes possible new kind of applications that exploit the person's surrounding context. Augmented reality (AR) presents a particularly powerful user interface (UI) to context-aware computing environments. AR systems integrate virtual information into a person's physical environment so that he or she will perceive that information as existing in their surroundings. Mobile augmented reality systems (MARS) provide this service without constraining the individual’s whereabouts to a specially equipped area. Ideally, they work virtually anywhere, adding a palpable layer of information to any environment whenever desired. By doing so, they hold the potential to revolutionize the way in which information is presented to people. Computer-presented material is directly integrated with the real world surrounding the freely roaming person, who can interact with it to display related information, to pose and resolve queries, and to collaborate with other people. The world becomes the user interface. This chapter provides a detailed introduction to mobile AR technology with in-depth reviews of important topics, such as wearable display and computing hardware, tracking, registration, user interaction, heterogeneous UIs, collaboration, and UI management for situated computing. As part of this introduction, we define what we mean by augmented reality, give a brief overview of the history of the field in general, and review some important mobile AR system considerations. Section 9.2 discusses the potential and possibilities of MARS technology, with a detailed overview of prototype application areas, and reviews the challenges that impede immediate widespread commercial adoption. In Section 9.3 we take a closer look at the requirements and specific components of MARS, before examining UI concepts in Section 9.4. We conclude the chapter with an outlook on research directions.
Extracellular potassium concentrations in red blood cell suspensions after irradiation and washing.

BACKGROUND
Extracellular potassium concentration [K(+)e] increases with duration of red blood cell storage. Sometimes red blood cells (RBC) are washed before transfusion to infants to reduce [K(+)e] of these components. AABB standards permit storage of washed RBCs at 4 degrees C for 24 hours. The [K(+)e] of washed RBCs during storage is not known. Experiments were performed to provide those data.


STUDY DESIGN AND METHODS
One day after outdating, 26 RBC units were washed without irradiation or before or after irradiation (25 Gy), and [K(+)e] was measured for 24 hours. [K(+)e] was measured also immediately before transfusion of 29 nonoutdated irradiated and washed RBC units.


RESULTS
After washing, [K(+)e] increased in a time-dependent fashion. [K(+)e] increased more rapidly in preparations of irradiated than nonirradiated RBCs. [K(+)e] was less after washing after irradiation (1.6 +/- 0.3, 2.4 +/- 0.3, 3.0 +/- 0.3, 3.6 +/- 0.3. 4.2 +/- 0.4, 5.3 +/- 0.5, 8.6 +/- 1.0, and 14.3 +/- 1.3 mEq/L at 0, 1, 2, 3, 4, 6, 12, and 24 hr; mean +/- SD) than washing before irradiation (p < 0.001). The increase in [K(+)e] during the first 6 hours after washing after irradiation was linear (0.61 +/- 0.08 mEq K(+)/L/hr). The probability of a unit of RBCs having a [K(+)e] greater than 5 mEq per L is 0.0 to 0.2 percent 3 hours after washing irradiated RBCs and 0.0 to 1.1 percent 6 hours after washing nonirradiated RBCs.


CONCLUSIONS
[K(+)e] increases after washing irradiated and nonirradiated packed RBCs. After irradiation and washing, the [K(+)e] for the initial 6 hours can be predicted from the [K(+)e] immediately after washing. There is a low probability that a unit of RBCs would have a [K(+)e] greater than 5 mEq per L during 6 hours of storage at 4 degrees C after washing if the cells are not irradiated and for 3 hours if the cells are irradiated.
Identification of individual and few layers of WS2 using Raman Spectroscopy

Department of Physics and Center for 2-Dimensional and Layered Materials, The Pennsylvania State University, University Park, PA 16802, USA, Institute of Condensed Matter and Nanosciences (IMCN), Université catholique de Louvain (UCL), Chemin des étoiles 8, 1348 Louvain-la-Neuve, Belgium, Department of Materials Science and Engineering and Materials Research Institute, The Pennsylvania State University, University Park, PA 16802, USA & Research Center for Exotic Nanocarbons (JST), Shinshu University, Wakasato 4-17-1, Nagano 380-853, Japan.
Predictors and effects of alcohol use on liver function among young HCV-infected injection drug users in a behavioral intervention.

BACKGROUND & AIMS
Hepatitis C virus (HCV) screening can provide opportunities to reduce disease progression through counseling against alcohol use, but empirical data on this issue are sparse. We determined the efficacy of a behavioral intervention in reducing alcohol use among young, HCV-infected injection drug users (IDUs) (n=355) and assessed whether changes in liver enzymes were associated with changes in alcohol consumption.


METHODS
Both the intervention and attention-control groups were counseled to avoid alcohol use, but the intervention group received enhanced counseling. Logistic regression, ANOVA, and continuous time Markov models were used to identify factors associated with alcohol use, changes in mean ALT and AST levels, and change in alcohol use post-intervention.


RESULTS
Six months post-intervention, alcohol abstinence increased 22.7% in both groups, with no difference by intervention arm. Transition from alcohol use to abstinence was associated with a decrease in liver enzymes, with a marginally greater decrease in the intervention group (p=0.05 for ALT; p=0.06 for AST). In multivariate Markov models, those who used marijuana transitioned from alcohol abstinence to consumption more rapidly than non-users (RR=3.11); those who were homeless transitioned more slowly to alcohol abstinence (RR=0.47); and those who had ever received a clinical diagnosis of liver disease transitioned more rapidly to abstinence (RR=1.88).


CONCLUSIONS
Although, behavioral counseling to reduce alcohol consumption among HCV-infected IDUs had a modest effect, reductions in alcohol consumption were associated with marked improvements in liver function. Interventions to reduce alcohol use among HCV-infected IDUs may benefit from being integrated into clinical care and monitoring of HCV infection.
State of the evidence 2017: an update on the connection between breast cancer and the environment

BACKGROUND
In this review, we examine the continually expanding and increasingly compelling data linking radiation and various chemicals in our environment to the current high incidence of breast cancer. Singly and in combination, these toxicants may have contributed significantly to the increasing rates of breast cancer observed over the past several decades. Exposures early in development from gestation through adolescence and early adulthood are particularly of concern as they re-shape the program of genetic, epigenetic and physiological processes in the developing mammary system, leading to an increased risk for developing breast cancer. In the 8 years since we last published a comprehensive review of the relevant literature, hundreds of new papers have appeared supporting this link, and in this update, the evidence on this topic is more extensive and of better quality than that previously available.


CONCLUSION
Increasing evidence from epidemiological studies, as well as a better understanding of mechanisms linking toxicants with development of breast cancer, all reinforce the conclusion that exposures to these substances - many of which are found in common, everyday products and byproducts - may lead to increased risk of developing breast cancer. Moving forward, attention to methodological limitations, especially in relevant epidemiological and animal models, will need to be addressed to allow clearer and more direct connections to be evaluated.
Association between alcohol intake and serum sex hormones and peptides differs by tamoxifen use in breast cancer survivors.

OBJECTIVE
To measure the association between alcohol intake and 11 hormones and peptides in postmenopausal breast cancer survivors and to evaluate whether this association differs by tamoxifen use.


METHODS
Self-reported alcohol intake was assessed via food frequency questionnaire on average 30 months post-breast cancer diagnosis in 490 postmenopausal women from three western states. Concurrently, a fasting blood sample was obtained for assay of estrone, estradiol, free estradiol, testosterone, free testosterone, dehydroepiandrosterone sulfate (DHEAS), sex hormone-binding globulin (SHBG), leptin, C-peptide, insulin-like growth factor-I (IGF-I), and IGF-binding protein-3. Adjusted means of these hormones and peptides were calculated for categories of alcohol intake, overall and stratified by tamoxifen use.


RESULTS
The association between alcohol intake and serum hormone and peptide levels differed by tamoxifen use. We found statistically significant inverse associations between alcohol intake and both leptin and SHBG values but only among tamoxifen users. In women not using tamoxifen, we found a positive association between alcohol intake and DHEAS but no association in tamoxifen users.


CONCLUSION
Tamoxifen may modify the association between alcohol intake and serum hormones and peptides. The significant associations found for DHEAS and SHBG are in a direction considered unfavorable for breast cancer prognosis. Postmenopausal breast cancer survivors may benefit from decreasing their alcohol intake.
Online but Accurate Inference for Latent Variable Models with Local Gibbs Sampling

We study parameter inference in large-scale latent variable models. We first propose a unified treatment of online inference for latent variable models from a non-canonical exponential family, and draw explicit links between several previously proposed frequentist or Bayesian methods. We then propose a novel inference method for the frequentist estimation of parameters, that adapts MCMC methods to online inference of latent variable models with the proper use of local Gibbs sampling. Then, for latent Dirichlet allocation,we provide an extensive set of experiments and comparisons with existing work, where our new approach outperforms all previously proposed methods. This work is currently under review for JMLR [1] (submitted on July, 27 2016).
Phase II trial of bryostatin-1 in combination with cisplatin in patients with recurrent or persistent epithelial ovarian cancer: a California cancer consortium study

Background The California Cancer Consortium has performed a Phase II trial of infusional bryostatin, a protein kinase C inhibitor isolated from the marine invertebrate bryozoan, Bugula Neritina, a member of the phylum Ectoprocta, in combination with cisplatin, in patients (pts) with recurrent platinum-sensitive or resistant ovarian cancer (OC). Methods Pts received bryostatin 45 mcg/m2 as a 72 h continuous infusion followed by cisplatin 50 mg/m2. Cycles were repeated every 3 weeks. Dosages were chosen based on phase I data obtained by the CCC in a population of pts with mixed tumor types. Results Eight pts with recurrent or persistent epithelial OC received 23 cycles of treatment. All pts had received previous platinum-based chemotherapy; two pts had received one prior course, five had received two prior courses, and one had received three prior courses of chemotherapy. The median age was 64 (range 32–72), and Karnofsky performance status 90 (range 80–100). A median of 3 cycles of chemotherapy were delivered (range: 1–5). The median progression-free and overall survivals were 3 and 8.2 months respectively. Best responses included two partial responses (one in a platinum-resistant pt), three pts with stable disease, and three progressions. All pts experienced Grade 3 or 4 toxicities including severe myalgias/pain/fatigue/asthenia in six pts, and severe nausea/vomiting/constipation in two other pts. One pt experienced a seizure and liver function tests were elevated in one other. Conclusions A modest response rate is observed in pts with recurrent or persistent ovarian cancer treated with the combination of bryostatin and cisplatin. The toxicity profile, however, observed in this pt population (primarily severe myalgias), precludes tolerability and prevents this combination from further investigation at this dose and schedule. It is possible that platinum pre-exposure in OC patients exacerbates observed toxicity. Phase II dosages of investigational agents in OC pts that are determined by phase I trials in pts with other tumor types should be chosen cautiously.
White blood cell counts and neutrophil to lymphocyte ratio in the diagnosis of testicular cancer: a simple secondary serum tumor marker.

PURPOSE
The aim of the study was to investigate white blood cell counts and neutrophil to lymphocyte ratio (NLR) as markers of systemic inflammation in the diagnosis of localized testicular cancer as a malignancy with initially low volume.


MATERIALS AND METHODS
Thirty-six patients with localized testicular cancer with a mean age of 34.22±14.89 years and 36 healthy controls with a mean age of 26.67±2.89 years were enrolled in the study. White blood cell counts and NLR were calculated from complete blood cell counts.


RESULTS
White blood cell counts and NLR were statistically significantly higher in patients with testicular cancer compared with the control group (p<0.0001 for all).


CONCLUSIONS
Both white blood cell counts and NLR can be used as a simple test in the diagnosis of testicular cancer besides the well-known accurate serum tumor markers as AFP (alpha fetoprotein), hCG (human chorionic gonadotropin) and LDH (lactate dehydrogenase).
Risk factors for hyperferritinemia secondary to red blood cell transfusions in pediatric cancer patients.

BACKGROUND
Transfusion of packed red blood cells is common in pediatric cancer patients who receive chemotherapy. This study was done to identify characteristics of pediatric cancer patients at risk of hyperferritinemia secondary to frequent transfusions.


PROCEDURE
In this retrospective chart review, all pediatric cancer patients who completed chemotherapy from January 2007 to January 2012 and had an assessment of serum ferritin 6 months after the end of treatment were included. Variables included: age, sex, type of cancer diagnosis, weight and body surface area (BSA) at the time of diagnosis, number of transfusions, total transfused volume (TTV), total transfused volume per body weight (TVPBW), and weight and BSA change from the time of diagnosis to the time of ferritin check.


RESULTS
Of 109 eligible patients, 85 (78%) received transfusions. Sixteen patients (14.7%) had ferritin levels > 200 µg/L and four (3.7%) had ferritin levels > 1,000 µg/L. Although age, weight and BSA at cancer diagnosis, number of transfusions and TVPBW were correlated with the level of ferritin, independent risk factors were TTV (range 1,961-30,090 ml in patients with hyperferritinemia, P < 0.001) and BSA change from the time of diagnosis to the time of ferritin check (range -0.15 to 0.31 m(2) in patients with hyperferritinemia, P < 0.001). Increase in BSA was correlated with reduction of hyperferritinemia in follow-up ferritin measurements (P = 0.049).


CONCLUSIONS
In addition to TTV, change in BSA is an independent predictor for the degree and possibly persistence of hyperferritinemia in pediatric cancer patients and should be considered in decisions to initiate interventions.
Systematic comparison of technical details in CBB methods and development of a sensitive GAP stain for comparative proteomic analysis.

Considering the importance of CBB staining in visualizing proteins in 2-DE gels, any improvement in the existing protocols with high sensitivity and good MS compatibility is of significant importance. In this study, we systematically evaluated the effects of different staining parameters on CBB methods by 1-DE and 2-DE, and demonstrated that G-250 was more suitable for visualizing low-abundant proteins as well as generating more spots than R-250, whereas R-250 had a superior capability for quick staining of high-abundant proteins. The staining produced by mixing G-250 and R-250 in different ratios showed similar sensitivity. Compared with acetic acid, phosphoric acid produced more protein spots. Ammonium-based stain demonstrated a superior sensitivity than the aluminum-based one. Based on these findings, a new protocol using CBB G-250, ammonium sulfate and phosphoric acid (GAP) was developed by incorporating the fixation, sensitization and staining procedures together. The comparison of GAP with other methods revealed that GAP generated more protein spots and had wider applications. The identification of 11 proteins demonstrated that GAP was not only compatible with MS but also obviously reduced in vitro protein modification, and thus could be a preferable protocol in the future proteomic analysis.