LLukas22/scidocs huggingface dataset:
Information Systems Theorizing Based on Evolutionary Psychology: An Interdisciplinary Review and Theory Integration Framework

Evolutionary psychology holds great promise as one of the possible pillars on which information systems theorizing can take place. Arguably, evolutionary psychology can provide the key to many counterintuitive predictions of behavior toward technology, because many of the evolved instincts that influence our behavior are below our level of conscious awareness; often those instincts lead to behavioral responses that are not self-evident. This paper provides a discussion of information systems theorizing based on evolutionary psychology , centered on key human evolution and evolutionary genetics concepts and notions. It is argued here that there is often a need to integrate evolutionary and non-evolutionary theories, and four important preconditions for the successful integration of evolutionary and non-evolutionary theories are discussed. An example of integration of evolutionary and non-evolutionary theories is provided. The example focuses on one evolutionary information systems theory—media naturalness theory—previously developed as an alternative to media richness theory, and one non-evolutionary information systems theory, channel expansion theory.
Pharmacovigilance from social media: mining adverse drug reaction mentions using sequence labeling with word embedding cluster features

OBJECTIVE
Social media is becoming increasingly popular as a platform for sharing personal health-related information. This information can be utilized for public health monitoring tasks, particularly for pharmacovigilance, via the use of natural language processing (NLP) techniques. However, the language in social media is highly informal, and user-expressed medical concepts are often nontechnical, descriptive, and challenging to extract. There has been limited progress in addressing these challenges, and thus far, advanced machine learning-based NLP techniques have been underutilized. Our objective is to design a machine learning-based approach to extract mentions of adverse drug reactions (ADRs) from highly informal text in social media.


METHODS
We introduce ADRMine, a machine learning-based concept extraction system that uses conditional random fields (CRFs). ADRMine utilizes a variety of features, including a novel feature for modeling words' semantic similarities. The similarities are modeled by clustering words based on unsupervised, pretrained word representation vectors (embeddings) generated from unlabeled user posts in social media using a deep learning technique.


RESULTS
ADRMine outperforms several strong baseline systems in the ADR extraction task by achieving an F-measure of 0.82. Feature analysis demonstrates that the proposed word cluster features significantly improve extraction performance.


CONCLUSION
It is possible to extract complex medical concepts, with relatively high performance, from informal, user-generated content. Our approach is particularly scalable, suitable for social media mining, as it relies on large volumes of unlabeled data, thus diminishing the need for large, annotated training data sets.
Antipyretic activity of the extracts of Hibiscus sabdariffa calyces L . in experimental animals

Reanmongkol, W. and Itharat, A. Antipyretic activity of the extracts of Hibiscus sabdariffa calyces L. in experimental animals Songklanakarin J. Sci. Technol., March 2007, 29(Suppl. 1) : 29-38 The effects of the extracts from Hibiscus sabdariffa calyces L. (H. sabdariffa) on nociceptive response using writhing, hot plate and formalin test in mice and the antipyretic activity in yeast-induced fever in rats, were examined. Anti-inflammatory activity was also investigated on carrageenin-induced paw edema in rats. No acute toxicity was observed in mice after oral administration of the ethanol and aqueous extract of H. sabdariffa calyces at the dose of 15 g/kg. Oral administration of the ethanol extract at the dose of 800 mg/kg significantly decreased the number of contortions and stretchings induced by acetic acid in mice. The aqueous extracts had no effect on this test. Neither the ethanol nor aqueous extract had an effect in the formalin and hot plate tests in mice. The ethanol and the vacuum dried extract of H. sabdariffa calyces (200-800 mg/kg, p.o.) decreased the yeast-induced fever in rats. The H. sabdariffa extract had no effect on carrageenininduced paw edema in rats. These results suggest that the ethanol and aqueous extract (vacuum dry) of H. sabdariffa calyces possess antipyretic action through mechanisms that are different from that of aspirin.
Interdependence through time: relationships in post-Keynesian thought and the care literature.

Does Hyman Minsky's 'general interdependence through time' have anything to do with Carol Gilligan's 'narrative of relationships that extends over time'? Both post-Keynesian theory and the feminist 'care literature' embrace calendar time and fundamental uncertainty. Both investigate the properties of networks of wittingly-formed forward commitments between actors. If some prominent writers in the care literature are right, these networks merit their own social-ontological status, because they are reducible neither to individual behaviour nor structure. Copyright The Author 2010. Published by Oxford University Press on behalf of the Cambridge Political Economy Society. All rights reserved., Oxford University Press.
THE FOURFOLD PATTERN OF RISK ATTITUDES IN CHOICE AND PRICING TASKS

Using simple gambles with real payoffs we examine the robustness of the fourfold pattern of risk attitudes under two different elicitation procedures. That is, we determine if on average individuals are (1) risk-seeking over lowprobability gains, (2) risk-averse over high-probability gains, (3) risk-averse over low-probability losses, and (4) risk-seeking over high-probability losses. We find that participants’ risk attitudes are consistent with the fourfold pattern when using the Becker-DeGroot-Marschak procedure to elicit prices for the gambles. However, when instead relying on a simple choice-based elicitation where participants choose between the gamble and its expected value, individual decisions are not distinguishable from random choice. This sensitivity to the elicitation procedure holds both betweenand within-participants, and it remains even when participants review their price and choice decisions simultaneously and are allowed to change them. Given the greater complexity of the price elicitation procedure this finding may be further evidence that an increase in cognitive load exacerbates behavioral anomalies. JEL classification: D80.
Self-powered piezoelectric energy harvesting device using velocity control synchronized switching technique

With the rapid development of low power consumption electronics, wireless sensor networks (WSN) are highly investigated and used to improve our life quality. Using piezoelectric materials to transfer the mechanical energy into electrical energy for batteries of WSN in order to extend the life time is the focus in many researches in the recent years. It is important and efficient to improve the energy harvesting by designing an optimal interface between piezoelectric device and the load. In this paper, a self-powered piezoelectric energy harvesting device is proposed based on the velocity control synchronized switching technique (V-SSHI). Comparing to diode full bridge rectifier standard technique, the synchronized switching harvesting on inductor (SSHI) technique can highly improve harvesting efficiency. However, in real applications when the energy harvesting device is associated with WSN, the SSHI technique needs to be implemented and requires being self-powered. The conventional technique to implement the self-powered SSHI is to use bipolar transistor as voltage peak detector. In this paper, a new self-powered device is proposed, using velocity control to switch the MOSFET more accurately than in the conventional technique. The concept of design and theoretical analysis is presented in detail. Experimental results are examined and show better performance.
REFINE (REducing Falls in In-patieNt Elderly) using bed and bedside chair pressure sensors linked to radio-pagers in acute hospital care: a randomised controlled trial

BACKGROUND
falls in hospitals are a major problem and contribute to substantial healthcare burden. Advances in sensor technology afford innovative approaches to reducing falls in acute hospital care. However, whether these are clinically effective and cost effective in the UK setting has not been evaluated.


METHODS
pragmatic, parallel-arm, individual randomised controlled trial of bed and bedside chair pressure sensors using radio-pagers (intervention group) compared with standard care (control group) in elderly patients admitted to acute, general medical wards, in a large UK teaching hospital. Primary outcome measure number of in-patient bedside falls per 1,000 bed days.


RESULTS
1,839 participants were randomised (918 to the intervention group and 921 to the control group). There were 85 bedside falls (65 fallers) in the intervention group, falls rate 8.71 per 1,000 bed days compared with 83 bedside falls (64 fallers) in the control group, falls rate 9.84 per 1,000 bed days (adjusted incidence rate ratio, 0.90; 95% confidence interval [CI], 0.66-1.22; P = 0.51). There was no significant difference between the two groups with respect to time to first bedside fall (adjusted hazard ratio (HR), 0.95; 95% CI: 0.67-1.34; P= 0.12). The mean cost per patient in the intervention group was £7199 compared with £6400 in the control group, mean difference in QALYs per patient, 0.0001 (95% CI: -0.0006-0.0004, P= 0.67).


CONCLUSIONS
bed and bedside chair pressure sensors as a single intervention strategy do not reduce in-patient bedside falls, time to first bedside fall and are not cost-effective in elderly patients in acute, general medical wards in the UK.


TRIAL REGISTRATION
isrctn.org identifier: ISRCTN44972300.
Offshoring and Labor Markets

Offshoring and Labor Markets In this paper we survey the recent empirical literature on the effects of offshoring on wage, employment and displacement. We start with an overview of the measurement of offshoring, organizing our discussion around the three key elements of offshoring: that it involves intermediate inputs for production (vs. final goods for consumption); that it involves imported inputs (vs. domestically produced ones); and that the inputs involved could have been produced internally within the same firm. We then briefly discuss the theories of offshoring, and survey the literature that examines the wage effects of offshoring: the wave of studies using industry-level data; the wave using firm-level data; the wave using worker-level data; and the wave using matched worker-firm data. For each wave we highlight the identification strategies used, critically assess its strength and weakness, discuss its connections with theory, and draw out potential policy implications of its findings. Finally we survey the literature that examines how offshoring affects employment and displacement. We highlight the recent development of a novel cohort-based approach that is specifically designed to address selection with displacement, and capable of identifying the overall effects of offshoring, including wage, displacement, and all other types of transition. JEL Classification: F1, J2, J3, L2
Improvement in the Low Frequency Performance of Geometric Transition Radar Absorbers Using Square Loop Impedance Layers

A technique is described for improving the low frequency performance of geometric transition (GT) radar absorbers based on lossy foam pyramids. The technique makes use of the fact that at high frequencies, only the geometric transition region of the absorber is utilized whereas at low frequencies, the whole absorber thickness interacts with the incident wave. Hence the low frequency performance may be improved, without compromising that at high frequencies, by electrically loading the absorber base layer using one or more frequency selective surfaces (FSS) whose elements are typically in the form of single or nested loops. Other advantages of this technique include minimal increases in weight and manufacturing costs. The paper includes comparative predictions of unmodified and loaded GT absorber reflectivity at both normal and oblique incidence and discusses the effect on absorber performance of tolerance variations in the dimensions and location of the loading FSS elements. Finally, free-space reflectivity measurements on unmodified and loaded commercial absorber blocks are made over the frequency range 1-10 GHz and these confirm the validity of the technique.
Rough sets: Some extensions

In this article, we present some extensions of the rough set approach and we outline a challenge for the rough set based research. 2006 Elsevier Inc. All rights reserved.
Phase I clinical trial of histone deacetylase inhibitor: suberoylanilide hydroxamic acid administered intravenously.

PURPOSE
To evaluate the safety, pharmacokinetics, and biological activity of suberoylanilide hydroxamic acid (SAHA) administered by 2-h i.v. infusion in patients with advanced cancer.


EXPERIMENTAL DESIGN
SAHA was administered for 3 days every 21 days in part A and 5 days for 1-3 weeks in part B. Dose escalation proceeded independently in patients with solid tumor and hematological malignancies (part B only). Pharmacokinetic studies were performed along with assessment of acetylated histones in peripheral blood mononuclear cells and tumor tissues.


RESULTS
No dose-limiting toxicities were observed in 8 patients enrolled in part A (75, 150, 300, 600, and 900 mg/m(2)/day). Among 12 hematological and 17 solid tumor patients enrolled in part B (300, 600, and 900 mg/m(2)/day), therapy was delayed > or = 1 week for grade 3/4 leukopenia and/or thrombocytopenia in 2 of 5 hematological patients at 600 mg/m(2)/day x 5 days for 3 weeks. The maximal-tolerated dose was 300 mg/m(2)/day x 5 days for 3 weeks for hematological patients. One solid patient on 900 mg/m(2)/day x 5 days for 3 weeks developed acute respiratory distress and grade 3 hypotension. The cohort was expanded to 6 patients, and no additional dose-limiting toxicities were observed. Mean terminal half-life ranged from 21 to 58 min, and there was dose-proportional increase in area under the curve. An accumulation of acetylated histones in peripheral blood mononuclear cells up to 4 h postinfusion was observed at higher dose levels. Posttherapy tumor biopsies showed an accumulation of acetylated histones by immunohistochemistry. Four (2 lymphoma and 2 bladder) patients had objective tumor regression with clinical improvement in tumor related symptoms.


CONCLUSIONS
Daily i.v. SAHA is well tolerated, inhibits the biological target in vivo, and has antitumor activity in solid and hematological tumors.
Prolonged clinical benefit from joint distraction in the treatment of ankle osteoarthritis.

OBJECTIVE
Osteoarthritis (OA) is a degenerative disabling joint disease affecting more than 10% of the adult population. No validated disease-modifying treatment is available. Joint distraction is a relatively new approach to the treatment of severe ankle OA. Short-term (3 years) clinical benefit has been proven, but long-term effects remain to be evaluated.


METHODS
Patients with severe OA of the tibio-talar joint, who had been treated with Ilizarov joint distraction more than 7 years previously, were included. Pre-treatment data were obtained by retrospective analysis using questionnaires and patients' charts. Post-treatment assessments were undertaken using the same questionnaires and by physical examination. Three approaches were used and results were compared: the van Valburg score, the Ankle Osteoarthritis Scale (AOS), and a patient satisfaction questionnaire. Retrospectively and prospectively obtained data were available from eight patients for comparison.


RESULTS
Twenty-five out of 27 patients with severe ankle OA treated with Ilizarov joint distraction could be traced. Appropriate retrospective data could not be obtained from three patients. Six out of the 22 patients (27%) were failures. In 16 patients (73%), significant improvement in all clinical parameters was observed using each of the three approaches. Good correlations were found between the results of the three methods of assessment and retrospectively obtained pre-treatment values were very similar to the prospective data.


CONCLUSIONS
In 73% of the patients, significant clinical benefit from joint distraction of severe OA ankles was maintained for at least 7 years. There is, however, a need for further research to try and predict which patients will not respond to this unconventional form of major surgical intervention.
Comparison of toxin removal outcomes in online hemodiafiltration and intra-dialytic exercise in high-flux hemodialysis: A prospective randomized open-label clinical study protocol

BACKGROUND
Maintenance hemodialysis (HD) patients universally suffer from excess toxin load. Hemodiafiltration (HDF) has shown its potential in better removal of small as well as large sized toxins, but its efficacy is restricted by inter-compartmental clearance. Intra-dialytic exercise on the other hand is also found to be effective for removal of toxins; the augmented removal is apparently obtained by better perfusion of skeletal muscles and decreased inter-compartmental resistance. The aim of this trial is to compare the toxin removal outcome associated with intra-dialytic exercise in HD and with post-dilution HDF.


METHODS/DESIGN
The main hypothesis of this study is that intra-dialytic exercise enhances toxin removal by decreasing the inter-compartmental resistance, a major impediment for toxin removal. To compare the HDF and HD with exercise, the toxin rebound for urea, creatinine, phosphate, and β2-microglobulin will be calculated after 2 hours of dialysis. Spent dialysate will also be collected to calculate the removed toxin mass. To quantify the decrease in inter-compartmental resistance, the recently developed regional blood flow model will be employed. The study will be single center, randomized, self-control, open-label prospective clinical research where 15 study subjects will undergo three dialysis protocols (a) high flux HD, (b) post-dilution HDF, (c) high flux HD with exercise. Multiple blood samples during each study session will be collected to estimate the unknown model parameters.


DISCUSSION
This will be the first study to investigate the exercise induced physiological change(s) responsible for enhanced toxin removal, and compare the toxin removal outcome both for small and middle sized toxins in HD with exercise and HDF. Successful completion of this clinical research will give important insights into exercise effect on factors responsible for enhanced toxin removal. The knowledge will give confidence for implementing, sustaining, and optimizing the exercise in routine dialysis care. We anticipate that toxin removal outcomes from intra-dialytic exercise session will be comparable to that obtained by standalone HDF. These results will encourage clinicians to combine HDF with intra-dialytic exercise for significantly enhanced toxin removal.


TRIAL REGISTRATION
ClinicalTrials.gov number, NCT01674153.
Mathematical modeling of different types of instabilities in time fractional reaction-diffusion systems

In this article we investigate possible scenarios of pattern formations in reaction-diffusion systemswith time fractional derivatives. Linear stability analysis is performed for different values of derivative orders. Results of qualitative analysis are confirmed by numerical simulations of specific partial differential equations. Most attention is paid to two models: a fractional order reaction diffusion system with Bonhoeffer–van der Pol kinetics and to the Brusselator model. © 2009 Elsevier Ltd. All rights reserved.
Effect of extraction solvent on total phenol content, total flavonoid content, and antioxidant activity of Limnophila aromatica.

Limnophila aromatica is commonly used as a spice and a medicinal herb in Southeast Asia. In this study, water and various concentrations (50%, 75%, and 100%) of methanol, ethanol, and acetone in water were used as solvent in the extraction of L. aromatica. The antioxidant activity, total phenolic content, and total flavonoid content of the freeze-dried L. aromatica extracts were investigated using various in vitro assays. The extract obtained by 100% ethanol showed the highest total antioxidant activity, reducing power and DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging activity. The same extract also exhibited the highest phenolic content (40.5 mg gallic acid equivalent/g of defatted L. aromatica) and the highest flavonoid content (31.11 mg quercetin equivalent/g of defatted L. aromatica). The highest extraction yield was obtained by using 50% aqueous acetone. These results indicate that L. aromatica can be used in dietary applications with a potential to reduce oxidative stress.
Late vascular response to repeat stenting for in-stent restenosis with and without radiation: an intravascular ultrasound volumetric analysis.

BACKGROUND
Re-stenting of in-stent restenosis (ISR) improves acute angiographic results. Methods and Results- Volumetric intravascular ultrasound analysis was performed in 70 ISR lesions that received either placebo (n=36) or (192)Ir radiation (n=34). ISR lesions treated by re-stenting were divided into 3 groups: old stent not re-stented (A), old/new stent overlap (B), and new stent only (C). ISR lesions treated without re-stenting were categorized as D. In placebo patients, postintervention lumen volume index (LVI) was significantly greater in re-stented segments B and C than in non-re-stented segment A (P<0.05).At follow-up, however, LVI was similar in all 4 segments secondary to the increased intimal hyperplasia (IH) reaccumulation within the re-stented segments. In patients treated with (192)Ir radiation, LVI was maintained from baseline to follow-up only in non-re-stented segments A and D. Conversely, there was a significant decrease in LVI in re-stented segments B and C (P<0.05). Qualitatively, 79% of patients in the irradiated group had stent struts with undetectable neointimal versus only 27% in the placebo group (P<0.001). Coefficient of variation of IH reaccumulation was greater in re-stented segments of (192)Ir patients (B=57.3% and C=58.9%) than in re-stented segments in placebo patients (B=27.3% and C 26.8%) and non-re-stented segments in irradiated patients.


CONCLUSIONS
Additional lumen gain from re-stenting ISR lesions is counteracted by exaggerated neointimal proliferation in placebo patients. Maximum effectiveness and safety of radiation can be achieved for ISR lesions when treated without re-stenting. Thus, regardless of supplementary intravascular brachytherapy, repeat stenting strategies provided little long-term advantage.
Impedance Control of Exoskeleton Suit Based on Adaptive RBF Neural Network

Abstract—Exoskeleton suit is a typical human-machine system. Control the exoskeleton suit to track the pilot’s moving trajectory as well as to minimize the human-machine interaction force. The suit will help decrease the pilot’s power consumption and assist the pilot to carry heavy load. Impedance control was introduced to the control of exoskeleton suit. As the control laws that based on the dynamic model without model uncertainty compensation will increase the human-machine force, a RBF neural network with adaptive learning algorithm was used to compensate the model uncertainty. The stability analysis of the control law was given and the simulation results show the feasibility and validity of the proposed control law.