LLukas22/scidocs huggingface dataset:
What design science is not

European Journal of Information Systems (2008) 17, 441–443. doi:10.1057/ejis.2008.45 Your new issue of EJIS opens with two opinion articles, each of which is a response to one of our previous opinion articles. First, I have invited Ray Paul to reply to the opinion article in the last number written by Bob Galliers. Second, we have a deeply analytical article written by Steven Alter in response to Ray Paul’s 2007 editorial ‘Challenges to information systems: time to change’. This issue is our only special issue for 2008, and is dedicated to Design Science Research. Most of the articles came to us from among the best papers presented at the 2008 DESRIST conference (Design Science Research in Information Systems and Technology). The special issue is introduced by Robert Winter in his article ‘Design Science Research in Europe’. As this introduction explains, the community within information systems with an interest in design science research is engaged in a discourse of discovery. However, it cannot be said that there is yet broad agreement on terminology, methodology, evaluation criteria, etc. This discovery arena encompasses terms like design science, design research, science of design and design theory. Because there is some disagreement over what these terms mean, the conference (and as a consequence the special issue) adopted the term ‘Design Science Research’ as a broad term meant to encompass the various meanings of all of the others. (For the purposes at hand, I will use the term design science as shorthand for design science research.) This fundamental discourse is reminiscent of the long-running search for the meaning of the term ‘theory’. When it became clear that there would never be complete agreement among management scholars on exactly what sorts of things constitute theory, Robert Sutton and Barry Shaw suggested that since agreement seemed impossible on ‘what theory is’, the best that could be done would be to seek agreement on ‘what theory is not’ (Sutton & Staw, 1995). Perhaps those interested in design science should seek a similar model and agree on ‘what design science is not’.
IMPROVING TEXT CATEGORIZATION BY USING A TOPIC MODEL

Most text categorization algorithms represent a document collection as a Bag of Words (BOW).The BOW representation is unable to recognize synonyms from a given term set and unable to recognize semantic relationships between terms. In this paper, we apply the topic-model approach to cluster the words into a set of topics. Words assigned into the same topic are semantically related. Our main goal is to compare between the feature processing techniques of BOW and the topic model. We also apply and compare between two feature selection techniques: Information Gain (IG) and Chi Squared (CHI). Three text categorization algorithms: Naïve Bayes (NB), Support Vector Machines (SVM) and Decision tree, are used for evaluation. The experimental results showed that the topic-model approach for representing the documents yielded the best performance based on F1 measure equal to 79% under the SVM algorithm with the IG feature selection technique.
Restorative and orthodontic treatment of an adolescent patient with amelogenesis imperfecta.

The diagnosis of Amelogenesis Imperfecta (AI) in a young patient can present many complex restorative and orth odontic challenges for the pediatric dentist. These patients have traditionally been treated with a combination of extractions, composite bonding, stainless steel crowns, adhesive castings, over-dentures, and porcelain veneers. They often have anterior open bites or vertical deep bites which further complicate the restorative and orthodontic treatment considerations. This case report presents an alternative method of using stainless steel crowns, which have been pre-fitted and then professionally veneered, followed by limited orthodontic treatment in an adolescent female with Amelogenesis Imperfecta during the transitional growth period.
Wyner–Ziv Coding Over Broadcast Channels: Digital Schemes

This paper addresses lossy transmission of a common source over a broadcast channel when there is correlated side information at the receivers, with emphasis on the quadratic Gaussian and binary Hamming cases. A digital scheme that combines ideas from the lossless version of the problem, i.e., Slepian-Wolf coding over broadcast channels, and dirty paper coding, is presented and analyzed. This scheme uses layered coding where the common layer information is intended for both receivers and the refinement information is destined only for one receiver. For the quadratic Gaussian case, a quantity characterizing the combined quality of each receiver is identified in terms of channel and side information parameters. It is shown that it is more advantageous to send the refinement information to the receiver with ¿better¿ combined quality. In the case where all receivers have the same overall quality, the presented scheme becomes optimal. Unlike its lossless counterpart, however, the problem eludes a complete characterization.
Neutrino oscillations: Current status and prospects

I summarize the status of neutrino oscillations from world neutrino oscillation data with date of October 2005. The results of a global analysis within the three-flavour framework are presented. Furthermore, a prospect on where we could stand in neutrino oscillations in ten years from now is given, based on a simulation of upcoming long-baseline accelerator and reactor experiments.
Powering aerial surveillance drones

The presented article analyzes, adopts and develops new solutions with regard to the aerial electric supply solutions for operational surveillance drones. This article proposes a number of innovative new usages and original solutions for continuously operating surveillance drones on a predefined path or around a predefined perimeter and, afterwards, steps are discussed which have to be followed to provide ingredients and end-to-end systems in order to transform this project into reality i.e. the aerial electric supply of surveillance drones.
Airway management by physician-staffed Helicopter Emergency Medical Services – a prospective, multicentre, observational study of 2,327 patients

BACKGROUND
Despite numerous studies on prehospital airway management, results are difficult to compare due to inconsistent or heterogeneous data. The objective of this study was to assess advanced airway management from international physician-staffed helicopter emergency medical services.


METHODS
We collected airway data from 21 helicopter emergency medical services in Australia, England, Finland, Hungary, Norway and Switzerland over a 12-month period. A uniform Utstein-style airway template was used for collecting data.


RESULTS
The participating services attended 14,703 patients on primary missions during the study period, and 2,327 (16 %) required advanced prehospital airway interventions. Of these, tracheal intubation was attempted in 92 % of the cases. The rest were managed with supraglottic airway devices (5 %), bag-valve-mask ventilation (2 %) or continuous positive airway pressure (0.2 %). Intubation failure rates were 14.5 % (first-attempt) and 1.2 % (overall). Cardiac arrest patients showed significantly higher first-attempt intubation failure rates (odds ratio: 2.0; 95 % CI: 1.5-2.6; p < 0.001) compared to non-cardiac arrest patients. Complications were recorded in 13 %, with recognised oesophageal intubation being the most frequent (25 % of all patients with complications). For non-cardiac arrest patients, important risk predictors for first-attempt failure were patient age (a non-linear association) and administration of sedatives (reduced failure risk). The patient's sex, provider's intubation experience, trauma type (patient category), indication for airway intervention and use of neuromuscular blocking agents were not risk factors for first-attempt intubation failure.


CONCLUSIONS
Advanced airway management in physician-staffed prehospital services was performed frequently, with high intubation success rates and low complication rates overall. However, cardiac arrest patients showed significantly higher first-attempt failure rates compared to non-cardiac arrest patients. All failed intubations were handled successfully with a rescue device or surgical airway.


TRIAL REGISTRATION



STUDY REGISTRATION
www.clinicaltrials.gov NCT01502111 . Registered 22 December 2011.
Reducing loneliness amongst older people: a systematic search and narrative review.

OBJECTIVE
To investigate the effectiveness of recent social therapeutic interventions to reduce loneliness in older people.


METHOD
To examine this matter, a literature review, using seven databases, was undertaken using search terms relating to the themes of ageing, loneliness and social support. A total of 17 relevant studies relating to loneliness interventions were analysed.


RESULTS
Three studies reporting on new technologies and one on a group work intervention identified significant reductions in loneliness.


CONCLUSION
Further research into interventions using new technologies to reduce loneliness in older people is recommended.
EFFECTS OF a-INTERFERON AND STEROIDS ON CD 23 EXPRESSION AND RELEASE IN B-CELL CHRONIC LYMPHOCYTIC LEUKEMIA

Background. Since high CD23 expression and release have been reported in B-chronic lymphocytic leukemia (B-CLL), we investigated whether a-interferon or corticosteroids were able to modulate the expression and/or the release of this factor. Methods. CD23 expression was determined with FITC-labelled anti-CD23 monoclonal antibody, and sCD23 release with a sandwich enzyme immunoassay. Twenty-one patients affected by B-CLL (stage A or B) were studied before and after three different treatment regimens (a-interferon, corticosteroids, a-interferon + corticosteroids). Results. CD23 was highly expressed in the B-cells of all patients, and expression was not modified by any of the therapies. sCD23 release from leukemic cells was significantly greater (p<0.00001) in untreated subjects than controls, and in vitro treatment with phorbol myristate acetate (PMA) led to a 10-fold increase (p<0.0001) in sCD23 secretion. On the contrary, PMA did not increase sCD23 release in normal B cells. Treatment with corticosteroids (either alone or associated with a-interferon) reduced sCD23 secretion from leukemic cells, whereas a-interferon alone was not able to modify sCD23 release. Conclusions. Our data support the hypothesis that CD23 plays a role in the maintenance and progression of B-CLL and that the pharmacological modulation of this receptor/lymphokine could be useful in the therapy of B-CLL.
Use of oral anticoagulant drugs is associated with carotid intraplaque hemorrhage in atherosclerosis patients: a meta-analysis

Patients with carotid atherosclerosis, especially the elderly population, take antithrombotic medicine regularly. However, no previous meta-analysis has focused on one of the possible side effects of such drugs, namely intraplaque hemorrhage (IPH). To determine whether antiplatelet drugs or anticoagulants are associated with an increased risk of carotid IPH. We searched Pubmed, Embase, Ovid MEDLINE, Cochrane Library for relevant studies that were published in English, from January 1st, 1989 to January 1st, 2019. We pooled the odds ratio (OR) with 95% confidence interval (CI) from individual studies and conducted quality assessment, heterogeneity, publication bias analysis and sensitivity analysis. A total of four cross-sectional studies, involving 2714 participants with carotid atherosclerotic plaques was included into this meta-analysis. We found a significant association between the use of anticoagulants and higher risk of carotid IPH (OR 1.95; 95% CI 1.16–3.30, P = 0.92; I 2 = 0). No significant association was found between the use of antiplatelet drugs and increased risk of carotid IPH (OR 1.34; 95% CI 0.68–2.61, P = 0.03; I 2 = 65%). Our meta-analysis reveals that it is the use of oral anticoagulants rather than antiplatelet drugs that may be associated with an increased risk of carotid IPH in atherosclerosis patients.
Emodin-8-O-β-d-Glucoside from Polygonum Amplexicaule D. Don var. Sinense Forb. Promotes Proliferation and Differentiation of Osteoblastic MC3T3-E1 Cells

Polygonum amplexicaule D. Don var. sinense Forb. (Polygonaceae) (PAF) is a famous traditional herb used to treat fractures, rheumatoid arthritis, muscle injury and pain. The present study was designed to investigate a PAF derived-chemical compound emodin-8-O-β-D-glucoside (EG) on the proliferation and differentiation of osteoblastic MC3T3-E1 cell in vitro. A compound was isolated from PAF extract by HPLC and identified as emodin-8-O-β-D-glucoside (EG) by spectroscopic methods. EG significantly promoted cell proliferation at 0.1-100 ng/mL, and increased the cell proportion in S-phase from 16.34% to 32.16%. Moreover, EG increased alkaline phosphatase (ALP) expression in MC3T3-E1 cells at the concentration from 0.1 to 100 ng/mL and inhibited PGE(2 )production induced by TNF-α in osteoblasts at the concentrations ranging from 10-100 ng/mL, suggesting that cell differentiation was induced in MC3T3-E1 osteoblasts. Taken together, these results indicated compound EG directly stimulated cell proliferation and differentiation of osteoblasts, therefore this study preliminarily explored the pharmacological mechanism of PAF to promote the healing of bone rheumatism and various fractures.
GPS analysis of elite women's field hockey training and competition.

This study investigated the physiological demands of women's field hockey competition and compared these demands to those experienced during game-based training activities. Fourteen elite women field hockey players (mean +/- SD; age, 23.3 +/- 3.2 years; maximal oxygen consumption, 53.5 +/- 4.3 ml x kg(-1) x min(-1)) participated in this study. Global positioning satellite (GPS) system analysis was completed during 19 training appearances and 32 Australian Hockey League (AHL) appearances. All training sessions consisted of game-based activities (i.e., small-sided training games) that were played on a reduced-sized pitch. Movement was recorded by a global positioning satellite unit sampling at 5 Hz. Data were categorized into discreet movement velocity bands, corresponding to low-intensity (0-1 m.s(-1)), moderate-intensity (1-3 m.s(-1) and 3-5 m.s(-1)), and high-intensity (5-7 m.s(-1) and >7 m.s(-1)) activities. Players covered 6.6 km (range: 3.4-9.5 km) over the course of the match. Midfielders spent more time and covered greater distances in high-intensity running (i.e., >5 m.s(-1)) than strikers and defenders. The number of high-velocity and high-acceleration efforts over the course of a match was greater in midfielders. In comparison to competition, game-based training sessions resulted in more time spent in low-intensity (i.e., 0-1 m.s(-1)) activities and less time spent in moderate (i.e., 1-3 m.s(-1) and 3-5 m.s(-1)) and high-intensity (i.e., 5-7 m.s(-1) and >7 m.s(-1)) activities. Although game-based training is likely to be useful for improving the skill levels of players, the skill activities used in the present study did not reflect the physiological demands of competition, with players spending more time in low-intensity activities and less time in high-intensity activities than competition. Modifications in training group size and/or drill design and complexity may better simulate the physiological demands of competition.
Charismatic leadership and user acceptance of information technology

Received: 12 June 2006 Revised: 10 May 2007 Accepted: 22 July 2007 Abstract Although there is widespread agreement that leadership has important effects on information technology (IT) acceptance and use, relatively little empirical research to date has explored this phenomenon in detail. This paper integrates the unified theory of acceptance and use of technology (UTAUT) with charismatic leadership theory, and examines the role of project champions influencing user adoption. PLS analysis of survey data collected from 209 employees in seven organizations that had engaged in a large-scale IT implementation revealed that project champion charisma was positively associated with increased performance expectancy, effort expectancy, social influence and facilitating condition perceptions of users. Theoretical and managerial implications are discussed, and suggestions for future research in this area are provided. European Journal of Information Systems (2007) 16, 494–510. doi:10.1057/palgrave.ejis.3000682
R Development Core Team (2010): R: A language and environment for statistical computing

Copyright (©) 1999–2003 R Foundation for Statistical Computing. Permission is granted to make and distribute verbatim copies of this manual provided the copyright notice and this permission notice are preserved on all copies. Permission is granted to copy and distribute modified versions of this manual under the conditions for verbatim copying, provided that the entire resulting derived work is distributed under the terms of a permission notice identical to this one. Permission is granted to copy and distribute translations of this manual into another language, under the above conditions for modified versions, except that this permission notice may be stated in a translation approved by the R Development Core Team.
The benefits of inositol-stabilized arginine silicate as a workout ingredient

Background The purpose of this study was to examine the benefits of inositol-stabilized arginine silicate (ASI; Nitrosigine) as a workout ingredient in healthy adults. ASI has been previously shown to significantly enhance blood levels of arginine up to six hours post-dose and increase nitric oxide levels. To investigate reports of enhanced energy, increased muscle pump and stamina during workouts, and faster muscle recovery post-workout, ASI (1,500mg/ day) was tested in a double-blind placebo-controlled crossover-design (DBPC-X) study using the POMS vigor-activity and fatigue-inertia sub-scores, blood flow measurements, leg circumference measurements, and biomarkers of muscle recovery (creatine kinase (CK) and lactate dehydrogenase (LDH)) as outcome measures.
A Paediatric Interactive Therapy System for arm and hand rehabilitation

Paediatric rehabilitation using virtual reality systems pose unique usability challenges distinct from those in adult rehabilitation. These challenges relate to the different epidemiology and aetiology of childrenpsilas disorders requiring rehabilitation and the physical design of interactive virtual reality hardware for children of varying sizes. Just as importantly, children need highly entertaining interactive scenarios that suit their differing levels of cognitive development and thus their differing abilities to comprehend gaming scenarios. In this paper we present our virtual reality-based Paediatric Interactive Therapy System (PITS) designed specifically for upper arm rehabilitation in children aged from five years of age upwards. It incorporates a range of interchangeable position sensing devices (compass, bend sensor, pressure sensor and camera tracking) that can be adjusted to a large range of different hand sizes, and interactive gaming scenarios specifically designed for maximum entertainment value for children. We describe the neuroscientific principles behind our system, the technical details of the hardware components and the design of the interactive scenarios. An initial usability and patient acceptance pilot study has been conducted at the Rehabilitation Centre Affoltern of the University Childrenpsilas Hospital Zurich. To date all patients have accepted the system, and trained in reaching and grasping tasks at a far higher rate than in conventional occupational therapy. The system thus promises to be a valuable complement to conventional therapeutic programs offered in rehabilitation clinics.
Network analysis has diverse roles in drug discovery.

Computational biologists use network analysis to uncover relationships between various data types of interest for drug discovery. For example, signalling and metabolic pathways are commonly used to understand disease states and drug mechanisms. However, several other flavours of network analysis techniques are also applicable in a drug discovery context. Recent advances include networks that encompass relationships between diseases, molecular mechanisms and gene targets. Even social networks that mirror interactions within the scientific community are helping to foster collaborations and novel research. We review how these different types of network analysis approaches facilitate drug discovery and their associated challenges.
Extraction of Heart Rate Variability from Smartphone Photoplethysmograms

Heart rate variability (HRV) is a useful clinical tool for autonomic function assessment and cardiovascular diseases diagnosis. It is traditionally calculated from a dedicated medical electrocardiograph (ECG). In this paper, we demonstrate that HRV can also be extracted from photoplethysmograms (PPG) obtained by the camera of a smartphone. Sixteen HRV parameters, including time-domain, frequency-domain, and nonlinear parameters, were calculated from PPG captured by a smartphone for 30 healthy subjects and were compared with those derived from ECG. The statistical results showed that 14 parameters (AVNN, SDNN, CV, RMSSD, SDSD, TP, VLF, LF, HF, LF/HF, nLF, nHF, SD1, and SD2) from PPG were highly correlated (r > 0.7, P < 0.001) with those from ECG, and 7 parameters (AVNN, TP, VLF, LF, HF, nLF, and nHF) from PPG were in good agreement with those from ECG within the acceptable limits. In addition, five different algorithms to detect the characteristic points of PPG wave were also investigated: peak point (PP), valley point (VP), maximum first derivative (M1D), maximum second derivative (M2D), and tangent intersection (TI). The results showed that M2D and TI algorithms had the best performance. These results suggest that the smartphone might be used for HRV measurement.
Wound Healing Activity of Carallia brachiata Bark

The stem bark of Carallia brachiata was studied for wound healing activity. The bark was extracted with petroleum ether, ethyl acetate and methanol successively. All the extracts were screened for wound healing activity by excision and incision models in Wistar rats. The ethyl acetate and methanol extracts were found to possess significant wound healing activity. The extracts revealed the presence of sterols or triterpenoids, flavonoids, phenols, tannins, carbohydrates, fixed oils and fats.