LLukas22/scidocs huggingface dataset:
The Role of Analogy in the Institutionalization of Sustainability Reporting

We study institutional entrepreneurship in an emergent field by analyzing the case of the Global Reporting Initiative (GRI) and its efforts to purposefully institutionalize the practice of sustainability reporting. We suggest that analogies affect institutionalization processes through two mechanisms. In the early stages of institutionalization, analogy operates primarily as a normative mechanism, and adoption is driven mainly by an instrumental logic. This emphasis on similarity to existing institutions stresses conformity and promotes legitimacy. Yet analogies can also have a cognitive effect on institutional design, especially once initial acceptance from the environment has been secured, by directing attention toward incongruences between the emergent institution and its analogical source. Institutional entrepreneurship can spur innovation and departure from existing institutions by highlighting limitations of the analogical source and providing a compelling value-rational argument that underscores the worth of the new institution. This theoretical contribution helps explain how analogies to existing institutional practices can both provide legitimacy to novel institutions and constitute the basis for a creative process of institutional design.
Transdermal testosterone delivery: testosterone patch and gel

Testosterone replacement treatment is usually life-long. Fortunately, testosterone administration is relatively safe and until the age of 50 years few side effects are noted with normal doses of testosterone. After the age of 50 years when prostate disease becomes more prevalent, shorter-acting testosterone preparations, allowing a fast reduction of circulating testosterone levels, may be an advantage. Testosterone has an impact on sexual and non-sexual behaviour and short-acting testosterone preparations may be better suited for the initiation of long-term administration allowing the monitoring of behavioural effects. Testosterone can be delivered to the circulation through the intact skin, both genital and non-genital. Transdermal administration delivers testosterone at a controlled rate into the systemic circulation, avoiding hepatic first pass and reproducing the diurnal rhythm of testosterone secretion and without the peak and trough levels observed with the use of the traditional long-acting testosterone injections. In conclusion, both the testosterone patch and testosterone gel are valuable contributions to androgen replacement treatment meeting the requirements specified for testosterone replacement treatment.
Signature-based videos' visual similarity detection and measurement

The quantity of digital videos is huge, due to technological advances in video capture, storage and compression. However, the usefulness of these enormous volumes is limited by the effectiveness of content-based video retrieval systems (CBVR) that still requires time-consuming annotating/tagging to feed the text-based search. Visual similarity is the core of these CBVR systems where videos are matched based on their respective visual features and their evolvement across video frames. Also, it acts as an essential foundational layer to infer semantic similarity at advanced stage, in collaboration with metadata. Furthermore, handling such amounts of video data, especially the compressed-domain, forces certain challenges for CBVR systems: speed, scalability and genericness. The situation is even more challenging with availability of nonpixelated features, due to compression, e.g. DC/AC coefficients and motion vectors, that requires sophisticated processing. Thus, a careful features’ selection is important to realize the visual similarity based matching within boundaries of the aforementioned challenges. Matching speed is crucial, because most of the current research is biased towards the accuracy and leaves the speed lagging behind, which in many cases affect the practical uses. Scalability is the key for benefiting from these enormous available videos amounts. Genericness is an essential aspect to develop systems that is applicable to, both, compressed and uncompressed videos. This thesis presents a signature-based framework for efficient visual similarity based video matching. The proposed framework represents a vital component for search and retrieval systems, where it could be used in three possible different ways: (1)Directly for CBVR systems where a user submits a query video and the system retrieves a ranked list of visually similar ones. (2)For text-based video retrieval systems, e.g. YouTube, when a user submits a textual description and the system retrieves a ranked list of relevant videos. The retrieval in this case works by finding videos that were manually assigned similar textual description (annotations). For this scenario, the framework could be used to enhance the annotation process. This is achievable by suggesting an annotations-set for the newly uploading videos. These annotations are derived from other visually similar videos that can be retrieved by the proposed framework. In this way, the framework could make annotations more relevant to video contents (compared to the manual way) which improves the overall CBVR systems’ performance as well. (3)The top-N matched list obtained by the framework, could be used as an input to higher layers, e.g. semantic analysis, where it is easier to perform complex processing on this limited set of videos.
ELECTROSTATIC FORCE THEORY FOR A MOLECULE AND INTERACTING MOLECULES PART 4, LONG-RANGE FORCES BETWEEN TWO ATOMS

Die Theorie der elektrostatischen Kraft wird auf Fernbereichswechselwirkungen zwischen zwei Atomen erweitert.
Real-Time Lip Tracking for Audio-Visual Speech Recognition Applications

Developments in dynamic contour tracking permit sparse representation of the outlines of moving contours. Given the increasing computing power of general-purpose workstations it is now possible to track human faces and parts of faces in real-time without special hardware. This paper describes a real-time lip tracker that uses a Kalman lter based dynamic contour to track the outline of the lips. Two alternative lip trackers, one that tracks lips from a proole view and the other from a frontal view, were developed to extract visual speech recognition features from the lip contour. In both cases, visual features have been incorporated into an acoustic automatic speech recogniser. Tests on small isolated-word vocabularies using a dynamic time warping based audiovisual recogniser demonstrate that real-time, contour-based lip tracking can be used to supplement acoustic-only speech recognisers enabling robust recognition of speech in the presence of acoustic noise.
Can yeast isolation be predicted in complicated secondary non-postoperative intra-abdominal infections?

INTRODUCTION
The aim of this study was to create a predictive score for yeast isolation in patients with complicated non-postoperative intra-abdominal infections (CNPIAI) and to evaluate the impact of yeast isolation on outcome.


METHODS
All patients with a CNPIAI undergoing emergency surgery over a three-year period were included in the retrospective cohort (RC, n = 290). Patients with a yeast-positive peritoneal fluid culture (YP) were compared with patients with a yeast-negative culture (YN). Multivariate logistic regression was used to identify factors independently associated with yeast isolation and a predictive score was built. The score's performance was then established in the prospective cohort (PC, n = 152) over an 18-month period. Outcome of the whole cohort was evaluated and independent risks factors of mortality searched.


RESULTS
In the RC, 39 patients (13.4%) were YP. Four factors were independently associated with the YP group: length of stay before surgery ≥48 h (odds ratio (OR) (95% confidence interval (CI)) = 3.1 (1.4 to 6.9), P = 0.004, 1 point), per-operative cardiovascular failure (2.4 (1.1 to 5.8), P = 0.04, 1 point), generalized peritonitis (6.8 (2.7 to 16.7), P <0.001, 2 points) and upper gastrointestinal tract perforation (2.5 (1.2 to 5.6), P = 0.02, 1 point). In the PC, the area under the curve (95%CI) of the predictive score's receiver operating characteristic curve was 0.79 (0.72 to 0.86). For predicting an intra-abdominal candidiasis (IAC), a score ≥3 had a sensitivity of 0.60, a specificity of 0.84, a positive predictive value of 0.49 and a negative predictive value of 0.89. Furthermore, yeast isolation was associated with worse outcome and independently associated with mortality in the whole cohort (OR = 2.15; 95%CI (1.03 to 4.46), P = 0.04).


CONCLUSIONS
The new predictive score can be used to rule out intra-abdominal candidiasis and thus avoid the initiation of antifungal treatment. It is suited to less severe infections than previously published scores. IAC is associated independently with an increased mortality in this population.
Toward new grounds in visualization

At the IEEE Visualization Conference 2004 in Austin, Texas, there was much discussion about the future of visualization research, especially about the future of scientific visualization. The fact that two visualization communities (SciVis and InfoVis) develop almost parallel to each other (instead of interweaving a bit) also raised questions, especially on the SciVis side.
Effect of Fructose on Glycemic Control in Diabetes

OBJECTIVE
The effect of fructose on cardiometabolic risk in humans is controversial. We conducted a systematic review and meta-analysis of controlled feeding trials to clarify the effect of fructose on glycemic control in individuals with diabetes.


RESEARCH DESIGN AND METHODS
We searched MEDLINE, EMBASE, and the Cochrane Library (through 22 March 2012) for relevant trials lasting ≥7 days. Data were aggregated by the generic inverse variance method (random-effects models) and expressed as mean difference (MD) for fasting glucose and insulin and standardized MD (SMD) with 95% CI for glycated hemoglobin (HbA(1c)) and glycated albumin. Heterogeneity was assessed by the Cochran Q statistic and quantified by the I(2) statistic. Trial quality was assessed by the Heyland methodological quality score (MQS).


RESULTS
Eighteen trials (n = 209) met the eligibility criteria. Isocaloric exchange of fructose for carbohydrate reduced glycated blood proteins (SMD -0.25 [95% CI -0.46 to -0.04]; P = 0.02) with significant intertrial heterogeneity (I(2) = 63%; P = 0.001). This reduction is equivalent to a ~0.53% reduction in HbA(1c). Fructose consumption did not significantly affect fasting glucose or insulin. A priori subgroup analyses showed no evidence of effect modification on any end point.


CONCLUSIONS
Isocaloric exchange of fructose for other carbohydrate improves long-term glycemic control, as assessed by glycated blood proteins, without affecting insulin in people with diabetes. Generalizability may be limited because most of the trials were <12 weeks and had relatively low MQS (<8). To confirm these findings, larger and longer fructose feeding trials assessing both possible glycemic benefit and adverse metabolic effects are required.
Next generation mentoring: Supporting teachers beyond induction

Mentoring teachers during the induction years has long been recognized as a powerful means to support and acclimate new teachers to the profession. Once the induction years are over however, mentoring is rarely offered for experienced educators. Additionally, teachers in their mid to late career stages often find professional development poorly suited to their interests or needs. As a result, frustration, cynicism, early attrition, and ‘burnout’ occurs. This study explores the perceptions of 20 experienced teachers in order to understand their professional needs and their perceptions about being mentored. Recommendations for the design of post induction mentoring programs are offered to schools looking to retain experienced teachers and inspire them for a full career of teaching. © 2018 Elsevier Ltd. All rights reserved.
Lincoln Near-Earth Asteroid Program (LINEAR)

The Lincoln Near-Earth Asteroid Research (LINEAR) program has applied electro-optical technology developed for Air Force Space Surveillance applications to the problem of discovering nearEarth asteroids (NEAs) and comets. This application is natural due to the commonality between the surveillance of the sky for manmade satellites and the search for near-Earth objects (NEOs). Both require the efficient search of broad swaths of sky to detect faint, moving objects. Currently, the Air Force Ground-based ElectroOptic Deep Space Surveillance (GEODSS) systems, which operate as part of the worldwide U.S. space surveillance network, are being upgraded to state-of-the-art charge-coupled device (CCD) detectors. These detectors are based on recent advances made by MIT Lincoln Laboratory in the fabrication of large format, highly sensitive CCDs. In addition, state-of-the-art data processing algorithms have been developed to employ the new detectors for search operations. In order to address stressing space surveillance requirements, the Lincoln CCDs have a unique combination of features, including large format, high quantum efficiency, frame transfer, high readout rate, and low noise, not found on any commercially available CCD. Systems development for the GEODSS upgrades has been accomplished at the Lincoln Laboratory Experimental Test Site (ETS) located near Socorro, New Mexico, over the past several years. Starting in 1996, the Air Force funded a small effort to demonstrate the effectiveness of the CCD and broad area search technology when applied to the problem of finding asteroids and comets. This program evolved into the current LINEAR program, which is jointly funded by the Air Force Office of Scientific Research and NASA. LINEAR, which started full operations in March of 1998, has discovered through September of 1999, 257 NEAs (of 797 known to date), 11 unusual objects (of 44 known), and 32 comets. Currently, LINEAR is contributing ∼70% of the worldwide NEA discovery rate and has single-handedly increased the observations submitted to the Minor Planet Center by a factor of 10. This paper covers the technology used by the program, the operations, and the detailed results of the search efforts.
Periodontal conditions in patients with Marfan syndrome – a multicenter case control study

BACKGROUND
Marfan syndrome (MFS) is a disorder of the connective tissues. Alterations of the elastic fibers may manifest in different tissues especially in the skeletal, cardiovascular and ocular system. Oral manifestations like orthodontic or skeletal anomalies and fragility of the temporomandibular joint have been well described by various authors. However, no data are available regarding a possible periodontal involvement of MFS. Hence, the aim of the present study was to investigate for the first time if MFS may increase the susceptibility to periodontitis.


METHODS
A comprehensive periodontal examination including documentation of probing pocket depth, gingival recession, clinical attachment level, and bleeding on probing was conducted in all patients. In addition, dental conditions were assessed by determining the Index for Decayed, Missing and Filled Teeth (DMFT) and a self-administered questionnaire was filled out by patients. For statistical analysis, the unpaired t-Test was applied (level of significance: p < 0.05). Both groups were matched concerning well known periodontal risk factors like age, gender and smoking habits.


RESULTS
82 participants, 51 patients with MFS (30 female and 21 male, mean age: 40.20 ± 15.35 years) and 31 sound controls (17 female and 14 male, mean age: 40.29 ± 13.94 years), were examined. All assessed periodontal and dental parameters were not significantly different between groups.


CONCLUSIONS
Based on our data, patients with MFS did not reveal a higher prevalence of periodontitis compared to the control group. However, Marfan patients showed a tendency to more inflammation signs, which can be explained by the crowded teeth. Therefore, a regular professional cleaning of the teeth is recommendable (i.e., 6 months intervals) in order to reduce the bacterial biofilm in the oral cavity and thus resulting in a decreased risk of systemic diseases, specifically endocarditis.
"Birds of a Feather": Does User Homophily Impact Information Diffusion in Social Media?

This article investigates the impact of user homophily on the social process of information diffusion in online social media. Over several decades, social scientists have been interested in the idea that similarity breeds connection—precisely known as “homophily”. “Homophily”, has been extensively studied in the social sciences and refers to the idea that users in a social system tend to bond more with ones who are “similar” to them than to ones who are dissimilar. The key observation is that homophily structures the ego-networks of individuals and impacts their communication behavior. It is therefore likely to effect the mechanisms in which information propagates among them. To this effect, we investigate the interplay between homophily along diverse user attributes and the information diffusion process on social media. Our approach has three steps. First we extract several diffusion characteristics along categories such as user-based (volume, number of seeds), topology-based (reach, spread) and time (rate)—corresponding to the baseline social graph as well as graphs filtered on different user attributes (e.g. location, activity behavior). Second, we propose a Dynamic Bayesian Network based framework to predict diffusion characteristics at a future time slice. Third, the impact of attribute homophily is quantified by the ability of the predicted characteristics in explaining actual diffusion, and external temporal variables, including trends in search and news. Experimental results on a large Twitter dataset are promising and demonstrate that the choice of the homophilous attribute can impact the prediction of information diffusion, given a specific metric and a topic. In most cases, attribute homophily is able to explain the actual diffusion and external trends by ∼ 15 − 25% over cases when homophily is not considered. Our method also outperforms baseline techniques in predicting diffusion characteristics subject to homophily, by ∼ 13 − 50%. ∗School of Computing, Informatics & Decision Systems Engineering, Arizona State University, Tempe, Arizona, USA. (munmun@asu.edu). †School of Arts, Media & Engineering, Arizona State University, Tempe, Arizona, USA. (hari.sundaram@asu.edu). ‡Collaborative Applications Research, Avaya Labs Research, Basking Ridge, New Jersey, USA. (ajita@avaya.com). §Collaborative Applications Research, Avaya Labs Research, Basking Ridge, New Jersey, USA. (doree@avaya.com). ¶School of Arts, Media & Engineering, Arizona State University, Tempe, Arizona, USA. (aisling.kelliher@asu.edu). 1 ar X iv :1 00 6. 17 02 v1 [ cs .C Y ] 9 J un 2 01 0
First-in-human evaluation of the safety and immunogenicity of a recombinant adenovirus serotype 26 HIV-1 Env vaccine (IPCAVD 001).

BACKGROUND
We report the first-in-human safety and immunogenicity assessment of a prototype Ad26 vector-based human immunodeficiency virus (HIV) vaccine in humans.


METHODS
Sixty Ad26-seronegative, healthy, HIV-uninfected subjects were enrolled in a randomized, double-blinded, placebo-controlled, dose-escalation phase 1 study. Five groups of 12 subjects received 10(9)-10(11) vp of the Ad26-EnvA vaccine (N = 10/group) or placebo (N = 2/group) at weeks 0 and 24 or weeks 0, 4, and 24. Safety and immunogenicity were assessed.


RESULTS
Self-limited reactogenicity was observed after the initial immunization at the highest (10(11) vp) dose. No product-related SAEs were observed. All subjects who received the Ad26-EnvA vaccine developed Ad26 NAb titers, EnvA-specific enzyme-linked immunosorbent assays (ELISA) titers, and EnvA-specific enzyme-linked immunospot assays (ELISPOT) responses. These responses persisted at week 52. At week 28 in the 10(9), 10(10), 10(11) vp 3-dose and the 10(10) and 5 × 10(10) vp 2-dose groups, geometric mean EnvA ELISA titers were 6113, 12 470, 8545, 3470, and 9655 and mean EnvA ELISPOT responses were 397, 178, 736, 196, and 1311 SFC/10(6) peripheral blood mononuclear cells, respectively.


CONCLUSION
This Ad26 vectored vaccine was generally safe and immunogenic at all doses tested. Reactogenicity was minimal with doses of 5 × 10(10) vp or less. Ad26 is a promising new vaccine vector for HIV-1.


CLINICAL TRIALS REGISTRATION
NCT00618605.
IRON-HF study: a randomized trial to assess the effects of iron in heart failure patients with anemia.

BACKGROUND
Anemia in heart failure patients and has been associated with increased morbi-mortality. Previous studies have treated anemia in heart failure patients with either erythropoietin alone or combination of erythropoietin and intravenous (i.v.) iron. However, the effect of i.v. or oral (p.o.) iron supplementation alone in heart failure patients with anemia was virtually unknown.


AIM
To compare, in a double-blind design, the effects of i.v. iron versus p.o. iron in anemic heart failure patients.


METHODS
IRON-HF study was a multicenter, investigator initiated, randomized, double-blind, placebo controlled trial that enrolled anemic heart failure patients with preserved renal function, low transferrin saturation (TSat) and low-to-moderately elevated ferritin levels. Interventions were Iron Sucrose i.v. 200 mg, once a week, for 5 weeks, ferrous sulfate 200 mg p.o. TID, for 8 weeks, or placebo. Primary endpoint was variation of peak oxygen consumption (peak VO2) assessed by ergospirometry over 3 month follow-up.


RESULTS
Eighteen patients had full follow-up data. There was an increment of 3.5 ml/kg/min in peak VO2 in the i.v. iron group. There was no increment in peak VO2 in the p.o. iron group. Patients' ferritin and TSat increased significantly in both treated groups. Hemoglobin increased similarly in all groups.


CONCLUSION
I.v. iron seems to be superior in improving functional capacity of heart failure patients. However, correction of anemia seems to be at least similar between p.o. iron and i.v. iron supplementation.