LLukas22/scidocs huggingface dataset:
Gondwana from top to base in space and time

Gondwana is reviewed from the unification of its several cratons in the Late Neoproterozoic, through its combination with Laurussia in the Carboniferous to form Pangea and up to its progressive fragmentation in the Mesozoic. For much of that time it was the largest continental unit on Earth, covering almost 100 million km 2 , and its remnants constitute 64% of all land areas today. New palaeogeographical reconstructions are presented, ranging from the Early Cambrian (540 Ma) through to just before the final Pangea breakup at 200 Ma, which show the distributions of land, shallow and deep shelves, oceans, reefs and other features at nine selected Palaeozoic intervals. The South Pole was within Gondwana and the Gondwanan sector of Pangea for nearly all of the Palaeozoic, and thus the deposition of significant glaciogenic rocks in the brief Late Ordovician (Hirnantian) and the much longer Permo-Carboniferous ice ages help in determining where their ice caps lay, and plotting the evaporites in the superterrane area indicates the positions of the subtropics through time. Reefs are also plotted and selected faunal provinces shown, particularly at times such as the Early Devonian (Emsian), when high climatic gradients are reflected in the provincialisation of shallow-marine benthic faunas, such as brachiopods. In Late Palaeozoic and Early Mesozoic times, Gondwana (with Africa at its core) lay over the African large low shear-wave velocity province (LLSVP), one of two major thermochemical piles covering ca. 10% of the core-mantle boundary. The edges of the LLSVPs (Africa and its Pacific antipode) are the plume generation zones (PGZs) and the source regions of kimberlite intrusions and large igneous provinces (LIPs). Our palaeomagnetic reconstructions constrain the configuration of Gondwana and adjacent continents relative to the spin axis, but in order to relate deep mantle processes to surface processes in a palaeomagnetic reference frame, we have also rotated the PGZs to account for true polar wander. In this way, we visualize how the surface distribution of LIPs and kimberlites relate to Gondwana’s passage over the PGZs. AC C EP TE D M AN U SC R IP T ACCEPTED MANUSCRIPT 2 There are only two LIPs in the Palaeozoic (510 and 289 Ma) that directly affected Gondwanan continental crust, and kimberlites are rare (83 in total). This is because Gondwana was mostly located between the two LLSVPs. The majority of Palaeozoic kimberlites are Cambrian in age and most were derived from the African PGZ. Sixty-six Early Mesozoic kimberlites are also linked to the African LLSVP. All known LIPs (Kalkarindji, Panjal Traps, Central Atlantic Magmatic Province and Karoo) from 510 to 183 Ma (the lifetime of Gondwana) were derived from plumes associated with the African LLSVP, and three of them probably assisted the breakup of Gondwana and Pangea.
Orofacial manual therapy improves cervical movement impairment associated with headache and features of temporomandibular dysfunction: a randomized controlled trial.

There is evidence that temporomandibular disorder (TMD) may be a contributing factor to cervicogenic headache (CGH), in part because of the influence of dysfunction of the temporomandibular joint on the cervical spine. The purpose of this randomized controlled trial was to determine whether orofacial treatment in addition to cervical manual therapy, was more effective than cervical manual therapy alone on measures of cervical movement impairment in patients with features of CGH and signs of TMD. In this study, 43 patients (27 women) with headache for more than 3-months and with some features of CGH and signs of TMD were randomly assigned to receive either cervical manual therapy (usual care) or orofacial manual therapy to address TMD in addition to usual care. Subjects were assessed at baseline, after 6 treatment sessions (3-months), and at 6-months follow-up. 38 subjects (25 female) completed all analysis at 6-months follow-up. The outcome criteria were: cervical range of movement (including the C1-2 flexion-rotation test) and manual examination of the upper 3 cervical vertebra. The group that received orofacial treatment in addition to usual care showed significant reduction in all aspects of cervical impairment after the treatment period. These improvements persisted to the 6-month follow-up, but were not observed in the usual care group at any point. These observations together with previous reports indicate that manual therapists should look for features of TMD when examining patients with headache, particularly if treatment fails when directed to the cervical spine.
Equivalence of recursive specifications in process algebra

textabstractWe define an equivalence relation on recursive specifications in process algebra that is model-independent and does not involve an explicit notion of solution. Then we extend this equivalence to the specification language $mu$CRL.
Анализ политического отчуждения в историко-философской мысли

The phenomenon of political estrangement is studied. It is analyzed from the historical and philosophical point of view. We research the transformation of the concept from 17 th century to present day. A state of modern Russian society is reviewed as well.
Neurological impressions on the organization of language networks in the human brain.

BACKGROUND
More than 95% of right-handed individuals, as well as almost 80% of left-handed individuals, have left hemisphere dominance for language. The perisylvian networks of the dominant hemisphere tend to be the most important language systems in human brains, usually connected by bidirectional fibres originated from the superior longitudinal fascicle/arcuate fascicle system and potentially modifiable by learning. Neuroplasticity mechanisms take place to preserve neural functions after brain injuries. Language is dependent on a hierarchical interlinkage of serial and parallel processing areas in distinct brain regions considered to be elementary processing units. Whereas aphasic syndromes typically result from injuries to the dominant hemisphere, the extent of the distribution of language functions seems to be variable for each individual.


METHOD
Review of the literature Results: Several theories try to explain the organization of language networks in the human brain from a point of view that involves either modular or distributed processing or sometimes both. The most important evidence for each approach is discussed under the light of modern theories of organization of neural networks.


CONCLUSIONS
Understanding the connectivity patterns of language networks may provide deeper insights into language functions, supporting evidence-based rehabilitation strategies that focus on the enhancement of language organization for patients with aphasic syndromes.
Brewer's conjecture and the feasibility of consistent, available, partition-tolerant web services

When designing distributed web services, there are three properties that are commonly desired: consistency, availability, and partition tolerance. It is impossible to achieve all three. In this note, we prove this conjecture in the asynchronous network model, and then discuss solutions to this dilemma in the partially synchronous model.
The influence of Mozart’s music on brain activity in the process of learning

OBJECTIVE
The study investigated the influence Mozart's music has on brain activity in the process of learning. A second objective was to test priming explanation of the Mozart effect.


METHODS
In Experiment 1 individuals were first trained in how to solve spatial rotation tasks, and then solved similar tasks. Fifty-six students were divided into 4 groups: a control one--CG who prior to and after training relaxed, and three experimental groups: MM--who prior to and after training listened to music; MS--who prior to training listened to music and subsequently relaxed; and SM--who prior to training relaxed and afterward listened to music. The music used was the first movement of Mozart's sonata (K. 448). In Experiment 2, thirty-six respondents were divided into three groups: CG, MM (same procedure as in Experiment 1), and BM--who prior to and after training listened to Brahms' Hungarian dance No. 5. In both experiments the EEG data collected during problem solving were analyzed using the methods of event-related desynchronization/synchronization (ERD/ERS) and approximated entropy (ApEn).


RESULTS
In the first experiment the respondents of the MM, MS, and SM groups showed a better task-performance than did the respondents of the CG group. Individuals of the MM group displayed less complex EEG patterns and more alpha band synchronization than did respondents of the other three groups. In Experiment 2 individuals who listened to Mozart showed a better task performance than did the respondents of the CG and BM groups. They displayed less complex EEG patterns and more lower-1 alpha and gamma band synchronization than did the respondents of the BM group.


CONCLUSIONS
Mozart's music, by activating task-relevant brain areas, enhances the learning of spatio-temporal rotation tasks.


SIGNIFICANCE
The results support priming explanation of the Mozart effect.
Non-functional Requirements in Architectural Decision Making

Software architects often must work with incomplete or ill-specified non-functional requirements (NFRs) and use them to make decisions. Through this process, existing NFRs are refined or modified and new ones emerge. Although much research has centered on how software architects treat NFRs, no empirical studies have investigated the state of the practice. A survey based on interviews with 13 software architects addressed two fundamental issues: how do architects face NFRs from an engineering perspective, and how do NFRs influence their decision-making? The survey revealed that architects usually elicit NFRs themselves in an iterative process; they usually don't document the NFRs and only partially validate them.
Ten-year follow-up survival of the Medicine, Angioplasty, or Surgery Study (MASS II): a randomized controlled clinical trial of 3 therapeutic strategies for multivessel coronary artery disease.

BACKGROUND
This study compared the 10-year follow-up of percutaneous coronary intervention (PCI), coronary artery surgery (CABG), and medical treatment (MT) in patients with multivessel coronary artery disease, stable angina, and preserved ventricular function.


METHODS AND RESULTS
The primary end points were overall mortality, Q-wave myocardial infarction, or refractory angina that required revascularization. All data were analyzed according to the intention-to-treat principle. At a single institution, 611 patients were randomly assigned to CABG (n=203), PCI (n=205), or MT (n=203). The 10-year survival rates were 74.9% with CABG, 75.1% with PCI, and 69% with MT (P=0.089). The 10-year rates of myocardial infarction were 10.3% with CABG, 13.3% with PCI, and 20.7% with MT (P<0.010). The 10-year rates of additional revascularizations were 7.4% with CABG, 41.9% with PCI, and 39.4% with MT (P<0.001). Relative to the composite end point, Cox regression analysis showed a higher incidence of primary events in MT than in CABG (hazard ratio 2.35, 95% confidence interval 1.78 to 3.11) and in PCI than in CABG (hazard ratio 1.85, 95% confidence interval 1.39 to 2.47). Furthermore, 10-year rates of freedom from angina were 64% with CABG, 59% with PCI, and 43% with MT (P<0.001).


CONCLUSIONS
Compared with CABG, MT was associated with a significantly higher incidence of subsequent myocardial infarction, a higher rate of additional revascularization, a higher incidence of cardiac death, and consequently a 2.29-fold increased risk of combined events. PCI was associated with an increased need for further revascularization, a higher incidence of myocardial infarction, and a 1.46-fold increased risk of combined events compared with CABG. Additionally, CABG was better than MT at eliminating anginal symptoms. Clinical Trial Registration Information- URL: http://www.controlled-trials.com.


REGISTRATION NUMBER
ISRCTN66068876.
'Educator talk' and patient change: some insights from the DESMOND (Diabetes Education and Self Management for Ongoing and Newly Diagnosed) randomized controlled trial.

AIMS
To determine whether differences in the amount of time educators talk during a self-management education programme relate to the degree of change in participants' reported beliefs about diabetes.


METHOD
Educators trained to be facilitative and non-didactic in their approach were observed delivering the DESMOND self-management programme for individuals newly diagnosed with Type 2 diabetes. Observers used 10-s event coding to estimate the amount of time educators spoke during different sessions in the programme. Facilitative as opposed to didactic delivery was indicated by targets for levels of educator talk set for each session. Targets were based on earlier pilot work. Using the revised Illness Perceptions Questionnaire (IPQ-R) and the Diabetes Illness Representations Questionnaire (DIRQ), participants completed measures of: perceived duration of diabetes (timeline IPQ-R), understanding of diabetes (coherence IPQ-R), personal responsibility for influencing diabetes (personal responsibility IPQ-R), seriousness of diabetes (seriousness DIRQ) and impact on daily life (impact DIRQ), before and after the education programme.


RESULTS
Where data from the event coding indicated educators were talking less and meeting targets for being less didactic, a greater change in reported illness beliefs of participants was seen. However, educators struggled to meet targets for most sessions of the programme.


CONCLUSION
The amount of time educators talk in a self-management programme may provide a practical marker for the effectiveness of the education process, with less educator talk denoting a more facilitative/less didactic approach. This finding has informed subsequent improvements to a comprehensive quality development framework, acknowledging that educators need ongoing support to facilitate change to their normal educational style.
Assessment of diclofenac or spinal manipulative therapy, or both, in addition to recommended first-line treatment for acute low back pain: a randomised controlled trial

BACKGROUND
We aimed to investigate whether the addition of non-steroidal anti-inflammatory drugs or spinal manipulative therapy, or both, would result in faster recovery for patients with acute low back pain receiving recommended first-line care.


METHODS
240 patients with acute low back pain who had seen their general practitioner and had been given advice and paracetamol were randomly allocated to one of four groups in our community-based study: diclofenac 50 mg twice daily and placebo manipulative therapy (n=60); spinal manipulative therapy and placebo drug (n=60); diclofenac 50 mg twice daily and spinal manipulative therapy (n=60); or double placebo (n=60). The primary outcome was days to recovery from pain assessed by survival curves (log-rank test) in an intention-to-treat analysis. This trial was registered with the Australian Clinical Trials Registry, ACTRN012605000036617.


FINDINGS
Neither diclofenac nor spinal manipulative therapy appreciably reduced the number of days until recovery compared with placebo drug or placebo manipulative therapy (diclofenac hazard ratio 1.09, 95% CI 0.84-1.42, p=0.516; spinal manipulative therapy hazard ratio 1.01, 95% CI 0.77-1.31, p=0.955). 237 patients (99%) either recovered or were censored 12 weeks after randomisation. 22 patients had possible adverse reactions including gastrointestinal disturbances, dizziness, and heart palpitations. Half of these patients were in the active diclofenac group, the other half were taking placebo. One patient taking active diclofenac had a suspected hypersensitivity reaction and ceased treatment.


INTERPRETATION
Patients with acute low back pain receiving recommended first-line care do not recover more quickly with the addition of diclofenac or spinal manipulative therapy.
Excess mortality related to seasonal influenza and extreme temperatures in Denmark, 1994-2010

BACKGROUND
In temperate zones, all-cause mortality exhibits a marked seasonality, and one of the main causes of winter excess mortality is influenza. There is a tradition of using statistical models based on mortality from respiratory illnesses (Pneumonia and Influenza: PI) or all-cause mortality for estimating the number of deaths related to influenza. Different authors have applied different estimation methodologies. We estimated mortality related to influenza and periods with extreme temperatures in Denmark over the seasons 1994/95 to 2009/10.


METHODS
We applied a multivariable time-series model with all-cause mortality as outcome, activity of influenza-like illness (ILI) and excess temperatures as explanatory variables, controlling for trend, season, age, and gender. Two estimates of excess mortality related to influenza were obtained: (1) ILI-attributable mortality modelled directly on ILI-activity, and (2) influenza-associated mortality based on an influenza-index, designed to mimic the influenza transmission.


RESULTS
The median ILI-attributable mortality per 100,000 population was 35 (range 6 to 100) per season which corresponds to findings from comparable countries. Overall, 88% of these deaths occurred among persons ≥ 65 years of age. The median influenza-associated mortality per 100,000 population was 26 (range 0 to 73), slightly higher than estimates based on pneumonia and influenza cause-specific mortality as estimated from other countries. Further, there was a tendency of declining mortality over the years. The influenza A(H3N2) seasons of 1995/96 and 1998/99 stood out with a high mortality, whereas the A(H3N2) 2005/6 season and the 2009 A(H1N1) influenza pandemic had none or only modest impact on mortality. Variations in mortality were also related to extreme temperatures: cold winters periods and hot summers periods were associated with excess mortality.


CONCLUSION
It is doable to model influenza-related mortality based on data on all-cause mortality and ILI, data that are easily obtainable in many countries and less subject to bias and subjective interpretation than cause-of-death data. Further work is needed to understand the variations in mortality observed across seasons and in particular the impact of vaccination against influenza.
Relationship between fluid intelligence and ability to benefit from cognitive-behavioural therapy in older adults: a preliminary investigation.

OBJECTIVE
The aim of this study was to conduct a preliminary evaluation of the hypothesis that fluid intelligence in older adults is associated with the ability to benefit from cognitive-behavioural therapy (CBT), but unrelated to the ability to benefit from non-directive supportive counselling (SC).


METHOD
A sample of 32 older adults who had completed a randomized controlled trial course of either CBT (N = 16) or SC (N = 16) for anxiety disorders took part in the study. The Raven's Coloured Progressive Matrices (RCPM) test was used to assess fluid intelligence. The Beck Anxiety Inventory change scores between pre-treatment and post-treatment were used as an index of ability to benefit from therapy. A measure of depressive symptomatology was also administered to control statistically for the effects of depression on intellectual functioning.


RESULTS
The results for the SC group showed a significant and positive association between fluid intelligence scores and anxiety change scores, such that older adults with higher levels of fluid intelligence demonstrated the most benefit from this intervention. In contrast, there was no significant association between level of fluid intelligence and ability to benefit from therapy in the CBT group.


CONCLUSION
CBT for anxiety disorders is suitable for older adults, irrespective of their fluid intelligence, while the nature of SC may render it more sensitive to level of fluid intelligence.
Chapter 4: The Development of General Secondary Education in the Far North

After the victory of the Great October Socialist Revolution, the peoples of the Far North were granted equal rights. However, more than legislation was needed to liquidate the inequality of such long standing and the exceedingly low level of culture that existed there. The Soviet government pursued a consistent policy to upgrade the economy and culture of those once-backward peoples.
Ecological and behavioral consequences of digestion in frugivorous animals

The postingestional effect of seed size and mass and nutrient composition on fruit profitability are reviewed. It is emphasized that profitability results from the interaction between fruit characteristics and the physiological and morphological traits of frugivores. The processes by which frugivores regurgitate or defecate seeds and the differential processing of the nutrient rich pulp and ballast in fruit are strongly dependent on the interaction between frugivore gut morphology and seed size. Euphonias that lack a functional gizzard defecate seeds, whereas tanagers that have a delete a functional gizzards regurgitate seeds. Some frugivores separate seeds from pulp and exocarp in the gizzard. It is hypothesized that the gizzard plays an important role in determining the postigestional fate of different pulp components. Although fruit nutrient content is often invoked as a determinant of frugivore feeding choices, studies that rely on proximal nutrient analysis, have often failed to find clear nutrient composition-preference correlations. It is argued that a partial reason for this failure is that proximal nutrient analysis ignores the complexities of fruit digestion. The ecological and physiological correlates of lipid and sugar assimilation are used to identify the limitations of traditional proximal nutrient analyses in fruit-frugivore studies. We suggest that recognizing the intricacies of the digestive characteristics of frugivores may reveal a much richer patterning in the interaction of frugivores with plants than has been previously hypothesized.
Mesenchymal stem cells are present in peripheral blood and can engraft after allogeneic hematopoietic stem cell transplantation.

BACKGROUND AND OBJECTIVES
Whether human mesenchymal stem cells (MSC) can be transplanted is controversial and their presence in peripheral blood is not fully accepted. In the present study we have analyzed whether, within the allogeneic transplantation setting, MSC are of host or donor origin.


DESIGN AND METHODS
Bone marrow MSC from 19 patients who had undergone allogeneic transplantation were expanded and identified using immunophenotypic markers. After that, chimerism studies were performed using reverse transcription polymerase chain reaction of short tandem repeat (STR) loci. Analyses were carried out at different time-points after transplantation, with a total of 44 samples studied. Bone marrow was used as the source of stem cells for transplantation in 4 cases and peripheral blood in 15 cases. The conditioning regimen was standard in 9 patients and non-myeloablative in 10 patients.


RESULTS
Our results show that in the great majority of cases analyzed (17 out 19), MSC were of host origin. However, in 2 patients with multiple myeloma who had received a reduced intensity transplantation using peripheral blood stem cells, MSC were partially of donor origin (60.17% and 26.13% of total MSC).


INTERPRETATION AND CONCLUSIONS
These findings indicate that after allogeneic transplantation MSC from the donor can engraft in bone marrow. Moreover, since the stem cells were obtained from peripheral blood, it can be concluded that MSC circulate among mobilized peripheral blood stem cells and can engraft in bone marrow after allogeneic transplantation.