LLukas22/scidocs huggingface dataset:
[Impact of sophrology on non-invasive ventilation tolerance in patients with acute respiratory failure].

OBJECTIVES
Non-invasive ventilation (NIV) in patients with acute respiratory failure (ARF) is subject to a large number of failures due to discomfort of the art, the feeling of difficulty breathing and pain. The purpose of this study was to evaluate the efficiency of sophrology to improve conditions for the realization of NIV in patients with ARF.


PATIENTS AND METHODS
In this prospective randomized and controlled study, consecutive patients with ARF were included. From the very first NIV session, they received either sophrology during the first 30 min of NIV (S group), or standard care by the same nurse during 30 min (T group). The hemodynamic and ventilatory data were recorded continuously; pain, respiratory difficulty and discomfort were measured with a numeric scale at the end of the session.


RESULTS
Thirty patients were included in the study, 27 have been analysed. Each patient received an average of four sessions NIV during the protocol. There was no significant difference between the two groups in terms of improvement in gas exchange. In contrast, there was a significant difference in terms of reduction of difficulty in breathing (-76%), discomfort (-60%) and decrease the pain (-40%) in the sophrology group (p<0.001). Respiratory rate, heart rate and systolic arterial blood pressure were decrease during NIV.


CONCLUSION
Sophrology constitutes aid for the achievement of the meetings of NIV in patients' IRA.
Does Animation in User Interfaces Improve Decision Making?

This paper reports a laboratory experiment that investigated the relative effects of images, transitions, and interactivity styles used in animated interfaces in two decision making domains. Interfaces used either realistic or abstract images, smooth or abrupt transitions, and parallel or sequential interactivity. Results suggest that decision making performance is influenced by the task domain, the user experience, the image, transition, and interactivity styles used in animated interfaces. Subjects performed better with animated interfaces based on realistic rather than abstract images. Subjects were more accurate with smooth rather than abrupt animation. Subjects were more accurate and enjoyed more the animation with parallel rather than sequential interactivity. Implications on the design of animated interfaces for decision making are provided. To account for appropriateness and interactivity, animation in HCI can be defined as: a series of varying images presented dynamically according to user actions in ways that help the user to perceive a continuous change over time and develop a more appropriate mental model of the task [7]. A task is generally considered a meaningful unit of work performance, and interactivity is usually defined by the visible or motor actions the user performs on the interface. This paper summarizes previous empirical research on animation and reports a laboratory study conducted to evaluate the decision making effectiveness of different types of images, transitions, and interactivity styles used in animated interfaces. The paper concludes with implications and recommendations concerning the design of animated interfaces for supporting decision making.
Tai Chi Chuan improves functional capacity after myocardial infarction: A randomized clinical trial.

BACKGROUND
Patients with a recent myocardial infarction (MI) present a reduction in functional capacity expressed as a decrease in peak oxygen consumption (Vo2 peak). The impact of a Tai Chi Chuan (TCC) cardiac rehabilitation program for patients recovering from recent MI has yet to be assessed. Our goal is to evaluate functional capacity after a TCC-based cardiac rehabilitation program in patients with recent MI.


METHODS
A single-blind randomized clinical trial was conducted. The researchers who performed the tests were blinded to group allocation. Between the 14th and 21st days after hospital discharge, all patients performed a cardiopulmonary exercise testing and a laboratory blood workup. Mean age was similar (56±9 years in the TCC group and 60±9 years in the control group). Patients allocated to the intervention group performed 3 weekly sessions of TCC Beijin style for 12 weeks (n=31). The control group participated in 3 weekly sessions of full-body stretching exercises (n=30).


RESULTS
After the 12-week study period, participants in the TCC group experienced a significant 14% increase in Vo2 peak from baseline (21.6 ± 5.2 to 24.6 ± 5.2 mL/kg per minute), whereas control participants had a nonsignificant 5% decline in Vo2 peak (20.4 ± 5.1 to 19.4 ± 4.4 mL/kg per minute). There was a significant difference between the 2 groups (P<.0001).


CONCLUSIONS
Tai Chi Chuan practice was associated with an increase in Vo2 peak in patients with a recent MI and may constitute an effective form of cardiac rehabilitation in this patient population.
Chipping Away at Censorship Firewalls with User-Generated Content

Oppressive regimes and even democratic governments restrict Internet access. Existing anti-censorship systems often require users to connect through proxies, but these systems are relatively easy for a censor to discover and block. This paper offers a possible next step in the censorship arms race: rather than relying on a single system or set of proxies to circumvent censorship firewalls, we explore whether the vast deployment of sites that host user-generated content can breach these firewalls. To explore this possibility, we have developed Collage, which allows users to exchange messages through hidden channels in sites that host user-generated content. Collage has two components: a message vector layer for embedding content in cover traffic; and a rendezvous mechanism to allow parties to publish and retrieve messages in the cover traffic. Collage uses user-generated content (e.g., photo-sharing sites) as “drop sites” for hidden messages. To send a message, a user embeds it into cover traffic and posts the content on some site, where receivers retrieve this content using a sequence of tasks. Collage makes it difficult for a censor to monitor or block these messages by exploiting the sheer number of sites where users can exchange messages and the variety of ways that a message can be hidden. Our evaluation of Collage shows that the performance overhead is acceptable for sending small messages (e.g., Web articles, email). We show how Collage can be used to build two applications: a direct messaging application, and a Web content delivery system.
Microcontroller Based Home Security System with GSM Technology

In this paper, design and implement of a microcontroller based home security system with GSM technology have been presented and analyzed. Two microcontrollers with other peripheral devices which include Light Emitting Diode (LED), Liquid Crystal Display (LCD), Buzzer and Global System for Mobile Communication (GSM) Module are responsible for reliable operation of the proposed security system. In addition, a mobile phone is interfaced with microcontroller through a Bluetooth device in order to control the system. Moreover, a manual keypad is another way to lock or unlock the system. A Compiler Code Vision AVR is used to design a program that controls the system along with maintaining all security functions. The designed program is applied in Proteus Software for simulation. At last, the results of practical circuit show the proper functions and also verify the reliable security within reasonable cost.
Comparison of semantic segmentation approaches for horizon/sky line detection

Horizon or skyline detection plays a vital role towards mountainous visual geo-localization, however most of the recently proposed visual geo-localization approaches rely on user-in-the-loop skyline detection methods. Detecting such a segmenting boundary fully autonomously would definitely be a step forward for these localization approaches. This paper provides a quantitative comparison of four such methods for autonomous horizon/sky line detection on an extensive data set. Specifically, we provide the comparison between four recently proposed segmentation methods; one explicitly targeting the problem of horizon detection[2], second focused on visual geo-localization but relying on accurate detection of skyline [15] and other two proposed for general semantic segmentation — Fully Convolutional Networks (FCN) [21] and SegNet[22]. Each of the first two methods is trained on a common training set [11] comprised of about 200 images while models for the third and fourth method are fine tuned for sky segmentation problem through transfer learning using the same data set. Each of the method is tested on an extensive test set (about 3K images) covering various challenging geographical, weather, illumination and seasonal conditions. We report average accuracy and average absolute pixel error for each of the presented formulation.
Anti-apoptotic genes, bag-1 and bcl-2, enabled hybridoma cells to survive under treatment for arresting cell cycle

Hybridoma 2E3-O cells were transfected with bcl-2 alone or with bcl-2 and bag-1 in combination. The bcl-2/bag-1 transfectant survived maintaining viability above 75% for almost 5 days when the cells were treated with excess (30 mM) thymidine for arresting cell cycle, whereas the mock transfectant survived for only 2 days, and the bcl-2 alone transfectant lived for 4 days. Owing to this extended viable culture period, the bcl-2/bag-1 transfectant produced twofold amount of antibody in comparison with the mock transfectant in non-proliferating state prepared by the excess thymidine treatment. When their proliferation was arrested by serum limitation, the bcl-2/bag-1 transfectant and the bcl-2 alone transfectant survived for 3 days maintaining viability above 75% while the mock transfectant survived only 1 day. The bcl-2/bag-1 transfectans produced the antibody at the rate three times as high as the bcl-2 alone transfectant and the mock transfectant in non-proliferating state established by serum limitation. Such genetic engineering of hybridoma cells for improving survival in the non-proliferating state will be useful for using nutrients in culture medium efficiently to produce antibody, since nutrients could be diverted from cell proliferation to antibody production in such non-proliferating viable cell culture.
A COMPARISON OF REPEATED HIGH DOSES AND REPEATED STANDARD DOSES OF EPINEPHRINE FOR CARDIAC ARREST OUTSIDE THE HOSPITAL

A BSTRACT Background Clinical trials have not shown a benefit of high doses of epinephrine in the management of cardiac arrest. We conducted a prospective, multicenter, randomized study comparing repeated high doses of epinephrine with repeated standard doses in cases of out-of-hospital cardiac arrest. Methods Adult patients who had cardiac arrest outside the hospital were enrolled if the cardiac rhythm continued to be ventricular fibrillation despite the administration of external electrical shocks, or if they had asystole or pulseless electrical activity at the time epinephrine was administered. We randomly assigned 3327 patients to receive up to 15 high doses (5 mg each) or standard doses (1 mg each) of epinephrine according to the current protocol for advanced cardiac life support. Results In the high-dose group, 40.4 percent of 1677 patients had a return of spontaneous circulation, as compared with 36.4 percent of 1650 patients in the standard-dose group (P=0.02); 26.5 percent of the patients in the high-dose group and 23.6 percent of those in the standard-dose group survived to be admitted to the hospital (P=0.05); 2.3 percent of the patients in the high-dose group and 2.8 percent in the standard-dose group survived to be discharged from the hospital (P=0.34). There was no significant difference in neurologic status according to treatment among those discharged. High-dose epinephrine improved the rate of successful resuscitation in patients with asystole, but not in those with ventricular fibrillation. Conclusions In our study, long-term survival after cardiac arrest outside the hospital was no better with repeated high doses of epinephrine than with repeated standard doses. (N Engl J Med 1998;339:1595-601.)
Bias, black lives, and academic medicine.

demonstrations, the largest coordinated protests at U.S. medical schools since the Vietnam War era, were initiated by medical students in California and spread across the country in response to the following call to action posted online at thefreethoughtproject.com: “We feel it is essential to begin a conversation about our role in addressing the explicit and implicit discrimination and racism in our communities and reflect on the systemic biases embedded in our medical education curricula, clinical learning environments, and administrative decision-making. We believe these discussions are needed at academic medical centers nationwide.” Though the stimulus for the die-ins was the nationwide protests in response to the killing of unarmed black men by police officers, the students demanded an examination of racial bias within our country’s academic medical centers. What are the systemic biases within academic medical centers, and what do they have to do with black lives? Two observations about health care disparities may be relevant. First, there is evidence that doctors hold stereotypes based on patients’ race that can influence their clinical decisions.1 Implicit bias refers to unconscious racial stereotypes that grow from our personal and cultural experiences. These implicit beliefs may also stem from a lack of day-to-day interracial and intercultural interactions. Although explicit race bias is rare among physicians, an unconscious preference for whites as compared with blacks is commonly revealed on tests of implicit bias.1 Second, despite physicians’ and medical centers’ best intentions of being equitable, black–white disparities persist in patient outcomes, medical education, and faculty recruitment. In the 2002 report Unequal Treatment, the Institute of Medicine (IOM) reviewed hundreds of studies of age, sex, and racial differences in medical diagnoses, treatments, and health care outcomes.2 The IOM’s conclusion was that for almost every disease studied, black Americans received less effective care than white Americans. These disparities persisted despite matching Bias, Black Lives, and Academic Medicine
Hepatic differentiation of human bone marrow-derived mesenchymal stem cells by tetracycline-regulated hepatocyte nuclear factor 3beta.

UNLABELLED
Human bone marrow-derived mesenchymal stem cells (BM-MSCs) are expected to be a potential source of cells for transplantation. Although recent reports have shown that isolated MSCs can differentiate into hepatocytes, the efficiency of differentiation is insufficient for therapeutic application. To circumvent this problem, it is necessary to understand the mechanisms of hepatic differentiation of human BM-MSCs. Hepatocyte nuclear factor 3beta (HNF3beta), a forkhead/winged helix transcription factor, is essential for liver development. In the present study, we established a tetracycline (Tet)-regulated expression system for HNF3beta in UE7T-13 BM-MSCs. HNF3beta expression significantly enhanced expression of albumin, alpha-fetoprotein (AFP), tyrosine amino transferase (TAT) and epithelial cell adhesion molecule (EpCAM) genes. The differentiated cells showed hepatocyte-specific functions including glycogen production and urea secretion. During treatment with the Tet-on system for 8 days, over 80% of UE7T-13 cells turned out to express albumin. Furthermore, the combination of Tet with basic fibroblast growth factor (bFGF) efficiently induced the genes such as albumin and TAT, which are associated with maturity of hepatocytes; however, it suppressed genes such as AFP and EpCAM, which are associated with immaturity of hepatocytes, suggesting that Tet-induced HNF3beta expression sensitizes BM-MSCs to bFGF signals. Finally, the results of the present study suggest that down-regulation of Wnt/beta-catenin signals caused by translocation of beta-catenin to cytoplasmic membrane is associated with hepatic differentiation of human BM-MSCs.


CONCLUSION
HNF3beta expression induced efficient differentiation of UE7T-13 human BM-MSCs.
Reservoir simulation-based modeling for characterizing longwall methane emissions and gob gas venthole production

Longwall mining alters the fluid-flow-related reservoir properties of the rocks overlying and underlying an extracted panel due to fracturing and relaxation of the strata. These mining-related disturbances create new pressure depletion zones and new flow paths for gas migration and may cause unexpected or uncontrolled migration ofgas into the underground workplace. One common technique to control methane emissions in longwall mines is to drill vertical gob gas ventholes into each longwall panel to capture the methane within the overlying fractured strata before it enters the work environment. Thus, it is important to optimize the well parameters, e.g., the borehole diameter, and the length and position of the slotted casing interval relative to the hctured gas-bearing zones. This paper presents the development and results of a comprehensive, "dynamic," three-dimensional reservoir model of a typical multipanel Pittsburgh coalbed longwall mine. The alteration of permeability fields in and above the panels as a result of the mininginduced disturbances has been estimated from mechanical modeling of the overlying rock mass. Model calibration was performed through history matching the gas production &om gob gas ventholes in the study area. Results presented in this paper include a simulation of gas flow patterns from the gas-bearing zones in the overlying strata to the mine environment, as well as the influence of completion practices on optimizing gas production from gob gas ventholes. Keywod: Longwall mining; Reservoir modeling; Ventilation; Gob gas ventholes; Reservoir simulation
Morphological and morphometric study on the early developmental stages of the Egyptian toad Bufo regularies Reuss

Aims: this study aimed to examine the developmental changes in external morphology characters for some embryonic larval period of Bufo regularis from river Nile, Assuit, Egypt. Methods: Our experiment started when tadpoles began to feed. the adapted embryos were divided into three large tanks, each with 200 embryos. collecting of samples started from feeding age every three days until end of metamorphosis (the absorption of tail). External measurements of the early developmental stages including body height (bH), body width (bW), eye diameter (ED), forelimb length (FLL), head-body length (H-bL), hind limb length (HLL), internarial distance (IND), interorbital distance (IOD), nostril diameter (ND), distance between nariel and orbital (NOD), tail length (tAL), tail height (tH), total length (tL), tail muscle height (tMH) and body weight (bWE) were recorded. results: the morphological description reported for each stage indicated many differences between the different developmental stages. conclusion: this study may be considered as morphological key for the different developmental stages of the Egyptian toad tadpoles (Bufo regularis). Alaa El-Din H. Sayed1, Ekbal T. Wassif1, Afaf I. Elballouz1,2 Affiliations: 1Zoology department, Faculty of Science, Assiut University, 71516Assiut, Egypt; 1, 2Zoology department, Faculty of Science, Misurate University, Misurate, Libya. Corresponding Author: Alaa El-Din Hamid Sayed, Zoology department, Faculty of Science, Assiut University, 71516Assiut, Egypt; Email: alaa_h254@yahoo.com (A. H. Sayed) Received: 21 October 2015 Accepted: 17 December 2015 Published: 29 February 2016
The Dark Side of Choice: When Choice Impairs Social Welfare

Abstract The provision of choice in terms of how people use goods and services has been proposed as a vehicle of improvement of social welfare. This article highlights some of the costs and benefits of creating choice, and it discusses how much choice policy makers and other agents (e.g., employers, retailers) should ideally grant and in what form they should grant it.
Modeling memory and perception

I present a framework for modeling memory, retrieval, perception, and their interactions. Recent versions of the models were inspired by Bayesian induction: We chose models that make optimal decisions conditioned on a memory/perceptual system with inherently noisy storage and retrieval. The resultant models are, fortunately, largely consistent with my models dating back to the 1960s, and are therefore natural successors. My recent articles have presented simplified models in order to focus on particular applications. This article takes a larger perspective and places the individual models in a more global framework. I will discuss (1) the storage of episodic traces, the accumulation of these into knowledge (e.g., lexical/semantic traces in the case of words), and the changes in knowledge caused by learning; (2) the retrieval of information from episodic memory and from general knowledge; (3) decisions concerning storage, retrieval, and responding. Examples of applications include episodic recognition and cued and free recall, perceptual identification (naming, yes–no and forced-choice), lexical decision, and long-term and short-term priming. © 2003 Cognitive Science Society, Inc. All rights reserved.
Stability in chemistry and biology: Life as a kinetic state of matter

Despite the considerable advances in our understanding of biological processes, the physicochemical relationship between living and nonliving systems remains uncertain and a continuing source of controversy. In this review, we describe a kinetic model based on the concept of dynamic kinetic stability that attempts to incorporate living systems within a conventional physicochemical framework. Its essence: all replicating systems, both animate and inanimate, represent elements of a replicator space. However, in contrast to the world of nonreplicating systems (all inanimate), where selection is fundamentally thermodynamic, selection within replicator space is effectively kinetic. As a consequence, the nature of stability within the two spaces is of a distinctly different kind, which, in turn, leads to different physicochemical patterns of aggregation. Our kinetic approach suggests: (a) that all living systems may be thought of as manifesting a kinetic state of matter (as apposed to the traditional thermodynamic states associated with inanimate systems), and (b) that key Darwinian concepts, such as fitness and natural selection, are particular expressions of more fundamental physicochemical concepts, such as kinetic stability and kinetic selection. The approach appears to provide an improved basis for understanding the physicochemical process of complexification by which life on earth emerged, as well as a means of relating life’s defining characteristics—its extraordinary complexity, its far-from-equilibrium character, and its purposeful (teleonomic) nature—to the nature of that process of complexification.