LLukas22/scidocs huggingface dataset:
Reliability of resting blood pressure measurement and classification using an oscillometric device in children with chronic kidney disease.

OBJECTIVE
To compare the reliability of blood pressure (BP) readings obtained with an oscillometric device with those obtained by auscultation and assess for differences in BP status classification based on the 2 techniques.


STUDY DESIGN
Resting BP was measured by auscultation and with an oscillometric device at the same encounter in 235 subjects enrolled in the Chronic Kidney Disease in Children study. Resting auscultatory BP values were averaged and compared with averaged oscillometric readings. BP agreement by the 2 methods was assessed using Bland-Altman plots, and BP status classification agreement was assessed by calculation of kappa statistics.


RESULTS
Oscillometric BP readings were higher than auscultatory readings, with a median paired difference of 9 mm Hg for systolic BP (SBP) and 6 mm Hg for diastolic BP (DBP). Correlation for mean SBP was 0.624 and for mean DBP was 0.491. The bias for oscillometric BP measurement was 8.7 mm Hg for SBP (P < .01) and 5.7 mm Hg for DBP (P < .01). BP status classification agreement was 61% for SBP and 63% for DBP, with Kappa values of .31 for SBP and .20 for DBP.


CONCLUSIONS
Compared with auscultation, the oscillometric device significantly overestimated both SBP and DBP, leading to frequent misclassification of BP status.
A generalized suboptimum unequally spaced channel allocation technique. I. In IM/DD WDM systems

Four-wave mixing (FWM) is the most serious fiber nonlinearity associated with low-input optical power levels in long-haul multichannel optical systems employing dispersionshifted fiber. To reduce the crosstalk due to FWM, a generalized suboptimum unequally spaced channel allocation (S-USCA) technique is proposed and investigated in this paper. Even though the developed technique is useful in combating FWM crosstalk in wavelength division multiplexing (WDM) lightwave systems up to 12 channels, its main virtue is in designing multichannel WDM lightwave systems with more than 12 channels . Comparisons of power penalty due to FWM between equal channel spacing (ECS) systems and the S-USCA systems are presented. It is shown that for an intensity modulation/direct detection (IM/DD) transmission system operating in an optical bandwidth of 16 nm with 0 dBm (1 mW) peak optical input power per channel, while a conventional ECS WDM system with 0.84-nm channel spacing cannot even achieve bit-error rate(BER) = 10 9, the suboptimum technique developed in this paper, for the same minimum channel spacing, can achieveBER = 10 9 with an FWM crosstalk power of less than 1 dB at the worst channel in a 20-channel WDM system.
Using LoRa for industrial wireless networks

The new concept of Industry 4.0 has been developed: it includes both Internet of Things (IoT) structure and the local networks that are still needed to carry out real-time tasks. However, forecasts of mass application of consumer IoT system have stimulated the development of new wireless technologies that may also be interesting for industry. In this paper, the LoRa technology is investigated for the implementation of industrial wireless networks suitable for sensors and actuators of the Industry 4.0 era. After a brief overview of LoRa and LoRaWAN, the paper deals with the discussion about using LoRa for industrial applications compared to traditional industrial wireless systems. With only very light modifications to the upper layer of LoRaWAN communication stack, a time slot channel hopping schema is possible. The experimental results show the feasibility of the proposed approach, which is compatible with requirements of soft real-time applications in process industry. In particular, proper time, frequency, and spreading factor planning may allow 6000 nodes accessed up to one minute cycle time.
Automorphisms of order three on numerical Godeaux surfaces

We prove that a numerical Godeaux surface cannot have an automorphism of order three. Mathematics Subject Classification (2000): 14J29 (primary); 14J50, 14E20 (secondary).
A Large Scale Study to Understand the Relation between Twitter and Financial Market

Twitter has transformed from an online platform for communication to a mega content generator for all kinds of topics. The topic of posts (or tweets) generated on Twitter cover diverse topics of interests. For example, politics, public personalities, events and corporate organizations. In this study, we analysed if tweets related to corporate organizations can predict the financial market. Our analysis is performed on a Twitter dataset which spans over more than two years and is related to more than 1723 stocks. To the best of our knowledge this amount of large and big dataset, specifically in terms of time length and stocks has not been studied in the past. Our quantitative analysis shows that on an average correlation between tweets and stocks' volume being traded is 0.29 on an average. In this empirical study, we also evaluated the stocks from Yahoo's sectors' categories perspective to find which sectors are more correlated than others. We also looked at the influence of important users, that is users with a large number of followers. Our results ally with the fact that important users contribute more in influencing the market [3] rather than the wisdom of the crowd [6]. The verification of our results using statistical approaches on a large dataset can be seen as a contribution in the area of financial studies using data from online platforms.
Social Security in Theory and Practice ( I ) : Facts and Political Theories

166 countries have some kind of public old age pension. What economic forces create and sustain old age Social Security as a public program? We document some of the internationally and historically common features of Social Security programs including explicit and implicit taxes on labor supply, payas-you-go features, intergenerational redistribution, benefits which are increasing functions of lifetime earnings and not means-tested. We partition theories of Social Security into three groups: “political”, “efficiency” and “narrative” theories. We explore three political theories in this paper: the majority rational voting model (with its two versions: “the elderly as the leaders of a winning coalition with the poor” and the “once and for all election” model), the “time-intensive model of political competition” and the “taxpayer protection model”. Each of the explanations is compared with the international and historical facts. A companion paper explores the “efficiency” and “narrative” theories, and derives implications of all the theories for replacing the typical pay-as-you-go system with a forced savings plan.
Total quality management and corporate culture: constructs of organisational excellence

There is a need for an appropriate culture to support the scope of Total Quality Management (TQM). Customer focus, systems approach, teamwork, involved management and continuous improvement are the aspects of TQM that facilitate improved organisational success, growth, and competitiveness. Many companies are now complementing continuous improvement with innovation, which is seen as the successful exploitation of new ideas. A clear synergy appears between these two corporate success factors as they are often integrated under an appropriate corporate culture for exploitation. The results of this can support substantial improvements in business performance and competitiveness of the company. With this in mind, this paper discusses the concept of corporate culture, places this social construct within the arena of TQM, and highlights the relationships that exist among culture, quality, and competitiveness using a case study.  2002 Elsevier Ltd. All rights reserved.
Lamivudine plus adefovir or telbivudine plus adefovir for chronic hepatitis B patients with suboptimal response to adefovir.

BACKGROUND
There is no standard management of chronic hepatitis B (CHB) patients with suboptimal response to nucleoside/nucleotide analogues (NAs). This study aimed to evaluate two different NA combination therapies in patients with suboptimal response to adefovir (ADV).


METHODS
In this study, 72 CHB patients with suboptimal response to ADV were assessed, with 37 patients receiving lamivudine plus ADV (group A) and 35 patients receiving telbivudine plus ADV (group B).


RESULTS
Baseline characteristics between two groups were similar. At month 12, rates of biochemical response (BR) and virological response (VR) were similar between groups A and B (17/19 versus 18/20 for BR, [P=0.269] and 30/37 versus 31/35 for VR [P=0.377]), and cumulative rates of serological response were greater in group B than in group A (10/26 versus 2/28 in hepatitis B e antigen [HBeAg] loss [P=0.006] and 7/26 versus 1/28 in HBeAg/hepatitis B e antibody seroconversion [P=0.022]). After 12-month treatment, 8.1% (3/37) of patients in group A and 5.7% (2/35) of patients in group B had VR; among patients in group A, two had rtM204V/I and rtL180M and one had rtN236T, whereas the two patients in group B had rtM204I+rtL180M.


CONCLUSIONS
Both combination therapies led to a significant decrease in HBV DNA. HBeAg serological outcomes were higher with telbivudine plus ADV combination therapy.
Prevalence, pattern and familial effects of substance use among the male college students -a north Indian study.

INTRODUCTION
Substance use refers to the use of any psychoactive substance or drug, including licit and illicit drugs, other than when medically indicated. Psychoactive substance use poses a threat to the health, social and economic fabric of families, communities and nations. Chandigarh has more than 0.2 million students from across the country pursuing their courses in higher education institutions. There is a very little information about pattern of drug dependence among the college students of Chandigarh,India.


OBJECTIVES
To study the prevalence and pattern of substance use among college students of Chandigarh and to study the psycho-social behaviour of youth and perceived reasons for using substances.


MATERIAL AND METHODS
A Cross - sectional community based study. A stratified multi-stage random sample design was adopted in study. The study instrument was a questionnaire which was developed by reviewing relevant literature and previously used standardized instruments and protocols including the WHO questionnaire. On the basis of 60% prevalence anticipated on the basis of pilot study, 90% confidence coefficient and 10% permissible error - sample size came out to be 256.


RESULTS
Prevalence of substance use was seen in 52.7% students belonging to age group 19 to 21 years. More prevalence of substance use was found among law students (76.2%) followed by the students from Art stream (62.5%). Among the users alcohol was most commonly used (53.5%), followed by smokers (27.3%), tobacco chewers (8.2%), cannabis (6.8%).49% of the users were using substances on daily basis, followed by 23% who using weekly.29.3% of users had father using any substance. Relief from psychological stress (66.0%) followed by easy availability (46.9%) were the most common reasons of substance abuse. that substances use is common among college going male students irrespective of their social demographic characteristics like age [OR 0.76, 95%CI (.443-1.317) religion [OR.859 95%CI (.461-1.598), parental education, occupation and socio-economic status. Therefore, interventions in terms of health education/counselling for reducing substance use among them should be adopted, irrespective of their socio-demographic characteristics. Suggestions: This study suggested some life style related interventions in order to reduce the problem of substance use.There is an utmost need to educate and counsel young students regarding harmful effects of substance use. Health education may be imparted in the school curriculum. Parents should also be educated on discouragement of substance use and on taking proper care of their children.
A phase 1 and pharmacokinetic study of gemcitabine and oxaliplatin in patients with solid tumors

Purpose: This dose escalation study aimed to determine the recommended doses, toxicity and pharmacokinetics of oxaliplatin and gemcitabine given on days 1 and 8 every 21 days. This schedule may maximize dose intensity of both drugs with acceptable or reduced toxicity. Patient and methods: Eligible patients had solid malignancies, no more than two prior courses of chemotherapy, ECOG performance status 0–2, neurotoxicity ≤ NCI-CTC grade 1 and adequate organ function. Dose escalation commenced at oxaliplatin 40 mg/m2 and gemcitabine 750 mg/m2, both given on days 1 and 8 every 21 days, and reached oxaliplatin 80 mg/m2 and gemcitabine 1,500 mg/m2. The two highest dose levels were each expanded to six patients to gain additional toxicity data. Results: There were no dose limiting toxicities related to treatment and an MTD was not reached. Five patients (24%) had grade 3 neutropenia, without associated infection, and seven patients (33%) had grade 3/4 thrombocytopenia. Neurotoxicity was mild and no worse than grade 1. Two patients with mesothelioma (10%) had partial responses and 11 patients (52%) had disease stabilization. No pharmacokinetic interaction between oxaliplatin and gemcitabine was detected. Dose intensity was maximal at level 4 (oxaliplatin 70 mg/m2 and gemcitabine 1,250 mg/m2). Conclusions: This schedule allows oxaliplatin and gemcitabine to be delivered at the full dose intensity of each drug with excellent tolerability and predictable pharmacokinetics. The recommended doses for phase II studies are oxaliplatin 70 mg/m2 and gemcitabine 1,250 mg/m2 on days 1 and 8 every 21 days.
Metamaterials for wireless power transfer

Recently, metamaterials have been developed for wireless power transfer applications. It has been shown that the near-field electromagnetic coupling between two resonant coils can be enhanced by a slab of metamaterial. With the assist of the metamaterial, the efficiency of wireless power transfer between the resonant coils can be greatly improved. In this paper, recent progress in this area will be presented: theoretical development of enhanced coil coupling with metamaterial will be briefly discussed; the design of metamaterial slabs for near-field wireless power transfer will be shown; recent experimental results on wireless power transfer efficiency improvement with metamaterial will also be presented.
Ontologies and How to Build Them

This paper is the product of an area-exam study. It intends to explain the concept of ontology in the context of knowledge engineering research, which is a sub-area of artiicial intelligence research. It introduces the state of the art on methodologies and tools for building ontologies. It also tries to point out some possible future directions for ontology research.
On lovely pairs of geometric structures

Abstract We study the theory of lovely pairs of geometric structures, in particular o-minimal structures. We use the pairs to isolate a class of geometric structures called weakly locally modular which generalizes the class of linear structures in the settings of SU-rank one theories and o-minimal theories. For o-minimal theories, we use the Peterzil–Starchenko trichotomy theorem to characterize for a sufficiently general point, the local geometry around it in terms of the thorn U-rank of its type inside a lovely pair.
Idiopathic Portal Hypertension in Patients With HIV Infection Treated With Highly Active Antiretroviral Therapy

OBJECTIVES:Idiopathic portal hypertension (IPH) is the presence of PH in the absence of liver disease. Recently, IPH was reported in HIV patients on highly active antiretroviral therapy (HAART). We describe for the first time the hepatic and systemic hemodynamic profile, liver stiffness, and histological features of eight patients with HIV-related IPH.METHODS:HIV-positive patients were identified from our IPH database over 3 years.RESULTS:Five patients presented with variceal bleeding, two with splenomegaly, and one with ascites. All had large esophageal varices. Median hepatic venous pressure gradient (HVPG) was 8 mm Hg (range 3.5–14.5), clearly underestimating the true portal pressure. This is probably because of a presinusoidal component of PH and because of the presence of intrahepatic venous collaterals. Median liver stiffness was 8.9 kPa (range 6.8–14.9) and was unreliable in predicting the presence of fibrosis or of esophageal varices. The main histological features were absence of portal vein radicles and areas of regenerating hepatocytes. Six patients (75%) developed portal vein thrombosis during a 2-year follow-up.CONCLUSIONS:There is a subset of HIV patients without cirrhosis but with PH compatible with IPH. In these patients, the hepatic and systemic hemodynamic profile is similar to other forms of IPH. The histological profile reflects an underlying vascular disorder affecting the medium-sized portal vein branches. Development of portal vein thrombosis is a frequent complication and requires close monitoring.
Radiation management for interventions using fluoroscopic or computed tomographic guidance during pregnancy: a joint guideline of the Society of Interventional Radiology and the Cardiovascular and Interventional Radiological Society of Europe with Endorsement by the Canadian Interventional Radiology

Lawrence T. Dauer, PhD, CHP, Raymond H. Thornton, MD, Donald L. Miller, MD, John Damilakis, PhD, Robert G. Dixon, MD, M. Victoria Marx, MD, Beth A. Schueler, PhD, Eliseo Vañó, PhD, Aradhana Venkatesan, MD, Gabriel Bartal, MD, Dimitrios Tsetis, MD, PhD, and John F. Cardella, MD, for the Society of Interventional Radiology Safety and Health Committee and the Cardiovascular and Interventional Radiology Society of Europe Standards of Practice Committee
Evaluating intertwined effects in e-learning programs: A novel hybrid MCDM model based on factor analysis and DEMATEL

Internet evolution has affected all industrial and commercial activity and accelerated e-learning growth. Due to cost, time, or flexibility for designer courses and learners, e-learning has been adopted by corporations as an alternative training method. E-learning effectiveness evaluation is vital, and evaluation criteria are diverse. A large effort has been made regarding e-learning effectiveness evaluation; however, a generalized quantitative evaluation model, which considers both the interaffected relation between criteria and the fuzziness of subjective perception concurrently, is lacking. In this paper, the proposed new novel hybrid MCDM model addresses the independent relations of evaluation criteria with the aid of factor analysis and the dependent relations of evaluation criteria with the aid of DEMATEL. The AHP and the fuzzy integral methods are used for synthetic utility in accordance with subjective perception environment. Empirical experimental results show the proposed model is capable of producing effective evaluation of e-learning programs with adequate criteria that fit with respondent’s perception patterns, especially when the evaluation criteria are numerous and intertwined. 2006 Elsevier Ltd. All rights reserved.
Image Edge Detection : A Review

Edge detection is important part of image processing for object detection. So it becomes extremely important to have a good understanding of edge detection algorithms. An edge is the real or imagined line that marks the limit and divides of plane, object or appearance from other places or things. This means that if the edges in an image can be identified accurately, all of the objects can be located and basic properties can be measured. This paper introduces a classification of most important and commonly used edge detection algorithms, namely Sobel, Robert, Prewitt, Laplacian of Gaussian, Canny, Ant colony Optimization. Keywords—Ant colony optimization, Canny, Edge Detection, Image Processing, Laplacian of Gaussian, Prewitt, Robert, Sobel.
Statins in Familial Hypercholesterolemia: Consequences for Coronary Artery Disease and All-Cause Mortality.

BACKGROUND
A statin-induced reduction of coronary artery disease (CAD) events and mortality has not been adequately quantified in patients with heterozygous familial hypercholesterolemia (FH).


OBJECTIVES
This study estimated the relative risk reduction for CAD and mortality by statins in heterozygous FH patients.


METHODS
The authors included all adult heterozygous FH patients, identified by the Dutch screening program for FH between 1994 and 2013, who were free of CAD at baseline. Hospital, pharmacy, and mortality records between 1995 and 2015 were linked to these patients. The primary outcome was the composite of myocardial infarction, coronary revascularization, and death from any cause. The effect of statins (time-varying) was determined using a Cox proportional hazard model, while correcting for the use of other lipid-lowering therapy, thrombocyte aggregation inhibitors, and antihypertensive and antidiabetic medication. The authors applied inverse-probability-for-treatment weighting (IPTW) to account for differences at baseline between statin users and never-users.


RESULTS
The authors obtained medical records of 2,447 patients, of whom 888 were excluded on the basis of age <18 years or previous CAD. Simvastatin 40 mg and atorvastatin 40 mg accounted for 23.1% and 22.8% of all prescriptions, respectively. Statin users (n = 1,041) experienced 89 CAD events and 17 deaths during 11,674 person-years of follow-up versus statin never-users (n = 518), who had 22 CAD events and 9 deaths during 4,892 person-years (combined rates 8.8 vs. 5.3 per 1,000 person-years, respectively; p < 0.001). After applying IPTW and adjusting for other medications, the hazard ratio of statin use for CAD and all-cause mortality was 0.56 (95% confidence interval: 0.33 to 0.96).


CONCLUSIONS
In patients with heterozygous FH, moderate- to high-intensity statin therapy lowered the risk for CAD and mortality by 44%. This is essential information in all cost-effectiveness studies of this disorder, such as when evaluating reimbursement of new lipid-lowering therapies.
Teacher Education, Critical Pedagogy, and Standards: An Exploration of Theory and Practice

Agreeing that a major goal of teacher education is to prepare individuals for informed citizenship in a democratic society, do standards lead toward social change promoting active citizenship of both teacher and student? We approach this question from two perspectives: one is a cultural approach grounded in critical pedagogy and the other is a policy approach based on the use of standards in teaching. We focus on a critical pedagogy in teacher education because of the goal of preparing citizens for participation in a democratic society. Highlighting three tenets of critical pedagogy, (a) reflection upon the individual’s culture or lived experience, (b) development of voice through a critical look at one’s world and society, and (c) transforming the society toward equality for all citizens through active participation in democratic imperatives, we focus on these tenets of critical theory in light of one set of teaching standards, specifically considering the standards’ facilitation toward or hindrance to social justice preparation in teacher education.
In Reply to Hubbeling.

More on Medical Education in Africa To the Editor: Dr. Hiatt and colleagues reported that strengthening the population health focus in East African health professions education can better prepare the African health care workforce to manage the infectious and chronic disease burden across the life span of the population they serve. With the population to economic diversity of medical students, nor probably to the racial, ethnic, and gender diversity in student bodies that is key to enhancing the cultural competence of medical school graduates.
Graph-based Ranking Algorithms for Sentence Extraction, Applied to Text Summarization

This paper presents an innovative unsupervised method for automatic sentence extraction using graphbased ranking algorithms. We evaluate the method in the context of a text summarization task, and show that the results obtained compare favorably with previously published results on established benchmarks.