LLukas22/scidocs huggingface dataset:
Information Theoretic Approach to Complexity Reduction of FIR Filter Design

This paper presents a new paradigm of design methodology to reduce the complexity of application-specific finite-impulse response (FIR) digital filters. A new adder graph data structure called the multiroot binary partition graph (MBPG) is proposed for the formulation of the multiple constant multiplication problem of FIR filter design. The set of coefficients in any fixed point representation is partitioned into symbols so that common subexpression identification and elimination become congruent to information parsing for data compression. A minimum number of different pairs or groups of symbols and residues can be used to code a set of coefficients based on their probability and conditional probability of occurrence. This ingenious concept enables the notion of entropy to be applied as a quantitative measure to evaluate the coding density of different compositions of symbols towards a set of coefficients. The minimal vertex set MBPG synthesized by our proposed information theoretic approach results in direct correspondences between the vertices and adders, and edges and physical interconnections. Unlike the common subexpression elimination algorithms based on other graph data structures, the symbol-level information carried in each vertex and the graph isomorphism of MBPG promise further fine-grain optimization in a reduced search space. One such optimization that has been exploited in this paper is the shift-inclusive computation reordering to minimize the width of every two's complement adder to further reduce the implementation cost and the critical path delay of the filter. Experiment results show that the proposed algorithm can contribute up to 19.30% reductions in logic complexity and up to 61.03% reduction in critical path delay over other minimization methods.
Merging augmented reality based features in mobile multimedia museum guides

Augmented Reality (AR), a computer science field considered by many as a subfield of the broader concept of Mixed Reality, could alter dramatically the way we interact not only with computers but also with the real environment surrounding us, as well as with other human beings. Augmented Reality has so far been used for applications linked with military training, medicine, maintenance, architecture and urban planning, tourism, and entertainment. This last category embraces museums, considered by many not only as research and exhibition spaces but also as important informal learning environments. Does Augmented Reality has the potential to break into museum and exhibition environments and revolutionize the way we see, approach and comprehend the exposed exhibits, alongside with more traditional interpretation and communication methods? This presentation examines both the state of the art in Augmented Reality Applications for Cultural Heritage and Mobile Multimedia Guides for the museum setting, proposing an Augmented Reality approach for the last. A taxonomy of augmented and non augmented functions is proposed, aspects of the development are presented and reasons that could favor or slow down the integration of Augmented Reality in mobile museum guides are tackled down. The potential mutual benefits both for the Augmented Reality community as well as for cultural heritage professional are also presented briefly.
Investigating the Relationship between Vocabulary Knowledge and Academic Success of Arabic Undergraduate Learners in Swansea University

The number of Arabic learners studying abroad has increased significantly over the last decade, and continues to increase. To test such students’ proficiency with English in an academic setting, most universities use standardised exams, such as the Test of English as a Foreign Language (TOEFL) or the International English Language Test System (IELTS). Although these tools are considered valid entry tests (Taylor and Falvey, 2007) they don’t appear to be useful predictors of academic success (e.g. Cotton and Conrow, 1998). We have therefore tried to find alternative measures to help refine our ability to predict academic performance. These include vocabulary knowledge using the XK_Lex test (Milton & AlMasrai, 2009); intelligence test (Wechsler Abbreviated Scale of Intelligence, WASI) and a foreign language aptitude test (Modern Language Aptitude Test, MLAT; Carroll & Sapon, 1959). 36 Arabic undergraduate students in Swansea University participated in this study. The results of the measures were correlated with participants’ Grade Point Average (GPA) as a measure of academic achievement. The findings suggest that a vocabulary knowledge threshold of 5000 and above is necessary for L2 learners to undertake international education; below this volume of vocabulary, they risk failure or academic hardship during their studies. No correlation was found between intelligence or aptitude test scores and learners’ academic achievement, but a significant relationship was noted between intelligence and vocabulary knowledge, confirming the trend that learners with high intelligence scores are more likely to possess an extensive vocabulary than learners with low intelligence scores.
Phase I study of AG2034, a targeted GARFT inhibitor, administered once every 3 weeks

Purpose: To identify a recommended phase II dose for the second generation glycinamide ribonucleotide transformylase (GARFT) inhibitor, AG2034, administered by intravenous bolus every 3 weeks without folate supplementation and to describe AG2034 pharmacokinetics. Methods: Adults with advanced malignancies were enrolled in cohorts of three per dose level with expansion to six upon observation of dose-limiting toxicity (DLT). The maximum tolerated dose (MTD) was defined as the dose at which two of up to six patients experienced DLT. Upon identification of an MTD and evidence of cumulative toxicity, a lower intermediate dose was explored as a candidate phase II dose. AG2034 plasma concentrations were measured using an ELISA assay. Results and conclusions: The recommended phase II dose is 5.0 mg/m2. DLTs were anemia, thrombocytopenia, mucositis, diarrhea, hyperbilirubinemia, fatigue, and insomnia. Toxicities were modestly cumulative over three courses. Pharmacokinetic analysis showed a dose-AUC0–24 relationship and a progressive increase in AG2034 AUC0–24 over three courses. Both pharmacokinetic and pharmacodynamic factors may contribute to the modest cumulative toxicity observed with AG2034.
Cut with the Kitchen Knife: The Weimar Photomontages of Hannah Hoch

Introduction: Representing the New Woman 1 The Berlin Dada Photomontages 2 Mass Media, Modernism, and the avant-garde 3 Hannah Hoch's Mass Media Scrapbook: Utopias of the Twenties 4 Portraits, Dancers, and Coquettes: The Modem Woman in Hoch's Photomontages, 1923-35 5 From An Ethnographic Museum 6 Androgyny and Spectatorship Conclusion Appendix A "A Glance Over My Life" by Hannah Hoch Appendix B "The Painter" by Hannah Hoch Appendix C: Chronology Appendix D: "A Few Words on Photomontage" by Hannah Hoch Notes Bibliography.
Factors influencing prostate cancer screening decisions among African American men.

PURPOSE
Due to controversy regarding prostate cancer screening, it is imperative that African American men make informed decisions. Little is known about the role of cultural factors in decision-making for prostate cancer screening among African American men. The purposes of this study were: 1) to investigate components involved with decision-making for prostate cancer screening among African American men; and 2) to identify cultural factors that may influence screening decisions.


METHODS
Six focus group sessions were conducted consisting of African American men between the ages of 40 and 70.


RESULTS
Eight themes emerged from the discussions about prostate cancer screening. These themes were: 1) men's knowledge of prostate cancer and clinical services; 2) prostate cancer as a threat to manhood; 3) screening as a threat to manhood; 4) self-awareness of health and well-being; 5) value of screening; 6) convenience of prostate specific antigen (PSA) screening; 7) misunderstanding of screening controversy; 8) distrust of the medical community; and 9) shared decision-making.


CONCLUSION
This study identifies cultural factors involved with decision-making for prostate cancer screening among African American men.
The Inhaled Steroid Treatment As Regular Therapy in Early Asthma (START) study 5-year follow-up: effectiveness of early intervention with budesonide in mild persistent asthma.

BACKGROUND
The Inhaled Steroid Treatment as Regular Therapy in Early Asthma (START) study enrolled 7241 patients aged 5 to 66 years with recent-onset, mild persistent asthma to assess early intervention with the inhaled corticosteroid budesonide on long-term asthma control.


OBJECTIVE
The open-label phase of the START study was included to determine the effect on lung function and asthma control of adding budesonide to the reference group patients who had not initially received inhaled corticosteroids.


METHODS
Patients were randomized to double-blind treatment with budesonide, 200 mug (those aged < 11 years) or 400 mug once daily, or placebo plus the usual asthma therapy for 3 years, after which all patients received 2 years of open-label treatment with budesonide once daily.


RESULTS
During the full 5-year study period, postbronchodilator FEV(1) percent predicted decreased, irrespective of randomized treatment during the double-blind phase, by an average of 2.22% (SE, 0.15%). However, patients with inhaled budesonide in the double-blind phase had a significantly lower risk (odds ratio, 0.61; P < .001) of a severe asthma-related event during the full 5-year study period than those in the reference group. Moreover, patients in the reference group used more additional asthma medications during both the open-label and double-blind phases.


CONCLUSIONS
In mild persistent asthma early intervention with inhaled budesonide was associated with improved asthma control and less additional asthma medication use.
Multi-relational Link Prediction in Heterogeneous Information Networks

Many important real-world systems, modeled naturally as complex networks, have heterogeneous interactions and complicated dependency structures. Link prediction in such networks must model the influences between heterogenous relationships and distinguish the formation mechanisms of each link type, a task which is beyond the simple topological features commonly used to score potential links. In this paper, we introduce a novel probabilistically weighted extension of the Adamic/Adar measure for heterogenous information networks, which we use to demonstrate the potential benefits of diverse evidence, particularly in cases where homogeneous relationships are very sparse. However, we also expose some fundamental flaws of traditional a priori link prediction. In accordance with previous research on homogeneous networks, we further demonstrate that a supervised approach to link prediction can enhance performance and is easily extended to the heterogeneous case. Finally, we present results on three diverse, real-world heterogeneous information networks and discuss the trends and tradeoffs of supervised and unsupervised link prediction in a multi-relational setting.
Effects of L-theanine or caffeine intake on changes in blood pressure under physical and psychological stresses

L-theanine, an amino acid contained in green tea leaves, is known to block the binding of L-glutamic acid to glutamate receptors in the brain, and has been considered to cause anti-stress effects by inhibiting cortical neuron excitation. Both L-theanine and caffeine, which green tea contains, have been highlighted for their beneficial effects on cognition and mood. In this study, we investigated the effects of orally administered L-theanine or caffeine on mental task performance and physiological activities under conditions of physical or psychological stress in humans. Fourteen participants each underwent three separate trials, in which they orally took either L-theanine + placebo, caffeine + placebo, or placebo only. The results after the mental tasks showed that L-theanine significantly inhibited the blood-pressure increases in a high-response group, which consisted of participants whose blood pressure increased more than average by a performance of a mental task after placebo intake. Caffeine tended to have a similar but smaller inhibition of the blood-pressure increases caused by the mental tasks. The result of the Profile of Mood States after the mental tasks also showed that L-theanine reduced the Tension-Anxiety scores as compared with placebo intake. The findings above denote that L-theanine not only reduces anxiety but also attenuates the blood-pressure increase in high-stress-response adults.
Recent advances in the diagnosis and management of diabetic neuropathy.

Neuropathy is a common complication of diabetes and is characterised by a progressive loss of peripheral nerve fibres. 2 There are a number of manifestations including both monoand polyneuropathies. In the diabetic foot, distal sensory polyneuropathy is seen most commonly. However, motor and autonomic fibres may also be involved and combined neuropathies frequently occur. The development of a neuropathy is linked to poor glycaemic control over many years and it increases in frequency with both age and the duration of diabetes.
Crystallographic and glycan microarray analysis of human polyomavirus 9 VP1 identifies N-glycolyl neuraminic acid as a receptor candidate.

UNLABELLED
Human polyomavirus 9 (HPyV9) is a closely related homologue of simian B-lymphotropic polyomavirus (LPyV). In order to define the architecture and receptor binding properties of HPyV9, we solved high-resolution crystal structures of its major capsid protein, VP1, in complex with three putative oligosaccharide receptors identified by glycan microarray screening. Comparison of the properties of HPyV9 VP1 with the known structure and glycan-binding properties of LPyV VP1 revealed that both viruses engage short sialylated oligosaccharides, but small yet important differences in specificity were detected. Surprisingly, HPyV9 VP1 preferentially binds sialyllactosamine compounds terminating in 5-N-glycolyl neuraminic acid (Neu5Gc) over those terminating in 5-N-acetyl neuraminic acid (Neu5Ac), whereas LPyV does not exhibit such a preference. The structural analysis demonstrated that HPyV9 makes specific contacts, via hydrogen bonds, with the extra hydroxyl group present in Neu5Gc. An equivalent hydrogen bond cannot be formed by LPyV VP1.


IMPORTANCE
The most common sialic acid in humans is 5-N-acetyl neuraminic acid (Neu5Ac), but various modifications give rise to more than 50 different sialic acid variants that decorate the cell surface. Unlike most mammals, humans cannot synthesize the sialic acid variant 5-N-glycolyl neuraminic acid (Neu5Gc) due to a gene defect. Humans can, however, still acquire this compound from dietary sources. The role of Neu5Gc in receptor engagement and in defining viral tropism is only beginning to emerge, and structural analyses defining the differences in specificity for Neu5Ac and Neu5Gc are still rare. Using glycan microarray screening and high-resolution protein crystallography, we have examined the receptor specificity of a recently discovered human polyomavirus, HPyV9, and compared it to that of the closely related simian polyomavirus LPyV. Our study highlights critical differences in the specificities of both viruses, contributing to an enhanced understanding of the principles that underlie pathogen selectivity for modified sialic acids.
P Systems for Array Generation and Application to Kolam Patterns

In the area of membrane computing, a new computability model, now called P system was introduced by PAUN (2002) inspired from the cell structure and its functioning. One area of P systems deals with string objects and rewriting rules. Recently, array P systems with array objects and array rewriting rules were introduced. Here we introduce a new class of array P systems called sequential/parallel rectangular array P systems generating pictures of rectangular arrays. These P systems have rectangular arrays as objects in the membranes and rules in the membranes are either context-free or regular with sequential horizontal rewriting or right-linear rules with vertical rewriting in parallel as in the two-dimensional (2D) matrix grammars (SIROMONEY et al., 1972). These P systems have more generative power and accordingly, they can generate kolam patterns that cannot be handled by 2D matrix grammars.
Software project risk analysis using Bayesian networks with causality constraints

Available online 8 November 2012
Programming with Arrows

ly, we think of the inputs and outputs of simulation arrows as signals, which are piecewise constant functions from time to values. Times may be any real number:
Geometric assessment of asymmetric septal hypertrophic cardiomyopathy by CMR.

OBJECTIVES
The aim of this study was to analyze the geometric pattern of hypertrophy (HT) in patients with asymmetrical septal hypertrophic cardiomyopathy (HCM) using cardiac magnetic resonance (CMR) and to test the hypothesis that at least in some patients, the HT follows a longitudinal spiral pattern.


BACKGROUND
The highly heterogeneous phenotypic expression of HCM is a well-known phenomenon. CMR has emerged as a robust 3-dimensional (3D) tomographic imaging technique that is increasingly used to explore phenotypic expression.


METHODS
Short-axis cine CMR was used to study the 3D extent of HT (i.e., radial, circumferential, and longitudinal extent, as well as the relation between circumferential and longitudinal extent). Inclusion criteria were septal wall thickness (WT) ≥15 mm and septal to free wall WT ratio >1.3.


RESULTS
CMR was performed in 132 patients. Maximal WT was 22 ± 5 mm, with a circumferential extent of 131 ± 51°, and a longitudinal extent of 64 ± 19%, resulting in a hypertrophied left ventricular (LV) surface of 26 ± 15%. Linear regression analysis showed in 86% of patients a consistent course of HT along the longitudinal direction. The HT invariably started at the basal anteroseptum and rotated, except in 2 patients, in a counterclockwise direction (CC-spiral patients) with a mean global rotation of 116 ± 68° (range 5° to 350°). After the CC-spiral patients were divided according to magnitude of rotation quartiles (Q1: 5° to 70°, Q2: 75° to 105°, Q3: 110° to 150°, and Q4: 155° to 350°), Q4 patients were significantly older and had more LV outflow tract obstruction and hypertension than patients without the spiraling pattern. In 11 patients, continuation of HT into an apical form of HCM was found.


CONCLUSIONS
Using 3D analysis, we found that the majority of patients with asymmetrical septal HCM in fact showed a spiral pattern of HT following a counterclockwise (or "left-handed") spiral trajectory. The variation in magnitude of rotation among patients, however, was highly variable. Further research is warranted to better understand the significance of the current findings, in particular to relate them to the genetic and morphological substrate, hemodynamic consequences, and patient outcome.
Preliminary Phytochemical, Antimicrobial and Acute Toxicity Studies of the Stem, bark and the Leaves of a cultivated Syzygium cumini Linn. (Family: Myrtaceae) in Nigeria

The phytochemical, antimicrobial and acute toxicity studies of the leaf and stem bark extracts of Syzygium cumini Linn. grown in Abuja, Nigeria was carried out. The phytochemical screening revealed the presence of carbohydrates, saponins, tannins, terpenes, volatile oil, sterols, resins balsam, phlobatanins and flavonoids in the leaves and stem bark of the species studied. Alkaloids and anthraquinones were absent in all the plant parts studied. 70% methanol extracts were used for antimicrobial and acute toxicity studies. The six test organisms used for antimicrobial studies were: Pseudomonas auriginosa, Escherichia coli, Staphylococcus aureus, Candida albicans, Bacillus subtilis and Salmonella typhii. The oil from the leaves showed activity on all the test organisms; the leaf extract showed activity on all test organisms except P. auriginosa while the stem bark extract showed no activity on any of the test organisms used. The oil had a saponification value of 363 and an acid value of 4.21. The lethal dose 50% (LD50) in mice was found to be >5000 mg/kg for the stem bark and at 3,873 mg/kg for the leaf extracts.
The strategic equivalence of rent-seeking, innovation, and patent-race games

Abstract We establish the strategic equivalence of a variety of rent-seeking contests, innovation tournaments, and patent-race games. The results allow us to disentangle negative and positive externalities, and to apply theorems and results intended for rent-seeking games to other games, and vice versa. We conclude with several examples that highlight the practical utility of our results.
Algorithms and Methods in Recommender Systems

Today, there is a big veriety of different approaches and algorithms of data filtering and recommendations giving. In this paper we describe traditional approaches and explane what kind of modern approaches have been developed lately. All the paper long we will try to explane approaches and their problems based on a movies recommendations. In the end we will show the main challanges recommender systems come across.
A pilot randomized trial comparing long-term effects of red and white wines on biomarkers of atherosclerosis (in vino veritas: IVV trial).

BACKGROUND
Since early 90', growing body of evidence indicates that the Mediterranean diet with mild to moderate consumption of wine, mostly red wine, has a protective effect on cardiovascular diseases. Several mechanisms have been discussed to participate in the beneficial effect of red wine, such as antioxidant or vasodilating activity. However, later it has been shown that also other alcoholic beverages have a protective effect on atherosclerosis. Up to now, data from the prospective, long-term, head-to-head comparisons of the effects of different drinks on markers of atherosclerosis are insufficient.


METHODS
The IVV (in vino veritas) study is a long-term, prospective, multicenter, randomized trial comparing the effect of red and white wines on the markers of atherosclerosis. One hundred and twenty healthy subjects with mild to moderate risk of atherosclerosis will be randomized to regular consumption of red wine (Pinot Noir) or white wine (Chardonnay-Pinot) for one year. The primary endpoint is the level of HDL-cholesterol at one year, while secondary endpoints are levels of other markers of atherosclerosis (LDL-cholesterol, C-reactive protein, myeloperoxidase, advanced oxidation protein product, interleukins 6 and 18, matrix metalloproteinases, glutathione s-transferase, monocyte chemoattractant protein 1, soluble CD40L).


CONCLUSION
The IVV trial is the first study focusing on the long-term prospective comparison of the effects of red and white wines consumption on HDL-cholesterol and other markers of atherosclerosis. Results of the IVV trial may extend our understanding of the widely discussed "French paradox" (Tab. 1, Ref. 21)