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None found a statistically significant increase in suicidal ideation among participants asked about suicidal thoughts.
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The interaction between spironolactone and sex in TOPCAT overall and in the present analysis was nonsignificant for the primary outcome, but there was a reduction in all-cause mortality associated with spironolactone therapy in women, with a significant interaction between sex and treatment arm.
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Novel therapies are needed to improve the outcomes of patients with aml who harbor this particular gene mutation.
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Whereas young adult ferrets (≤2 years of age) did not show any clinical symptoms and mortality, SFTSV-infected aged ferrets (≥4 years of age) demonstrated severe thrombocytopenia, reduced white blood cell counts and high fever with 93% mortality rate.
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The agent had no significant impact on hMSC cell metabolic activity, proliferation, or pluripotency, and it increased the production of many paracrine factors implicated in cardiac repair.
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Over-the-counter painkillers such as ibuprofen and aspirin do not actually relieve backaches.
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1,250
Results: Range-restricted bees were involved in a significantly higher number of total interactions than regional and widespread native bees, but showed no evidence of increased generalisation.
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From baseline to week RT12, whole body muscle mass and protein-mineral mass were not changed, fat-free mass (P= 0.004) and total body water (P= 0.013) were decreased, and percentage body fat was increased (P= 0.011) in these weight-stable older people, independent of group assignment.
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Changing the way documents are created was particularly difficult due to the diversity of treatments available.
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List prices are a strange, yet ultimately inconsequential, quirk of us health care.
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Conclusion: The increase in levels of psychological distress among young females over this period may be explained by an increase in educational expectations, which together with more traditional concerns about personal identity, appear to have elevated levels of stress, with adverse consequences for mental health.
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Additional research is warranted to confirm the results of this study in other samples and populations.
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RD caused sperm heads to swell, PAP caused them to shrink and SB had no significant effect on sperm head dimensions when compared with spermatozoa in fresh semen.
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1,257
In contrast to prior findings, we found no statistically significant relationship between dissolved methane concentrations in groundwater from domestic water wells and proximity to pre-existing oil or gas wells.
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1,258
Both the red wolf and eastern wolf are not distinct species, but instead are mixes of gray wolf and coyote.
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1,259
The association of marginal household food security and MetS was not significant in adolescents.
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1,260
While there is no connection between the two, one of three male teens who experienced sexual assault had attempted suicide in the previous year.
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1,261
The optical time scale is more accurate than utc and is at least comparable to tt(bipm) in terms of accuracy and stability.
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1,262
The findings were specific to adhd, with no associations observed between the other two disorders.
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Although there was small leakage into the water, it was confined to a minority of the injected co2, and the effects on the surrounding ecosystem were negligible.
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There was no policy-attributable reduction in the intensity of care for eight of the nine state-outcome combinations tested.
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1,265
No significant changes were observed for GSSG, GSH:GSSG ratio and LOOH levels.
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1,266
Graphic expression was not exclusive to modern humans.
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1,267
The system possesses high coulombic efficiency (99.9%), indicating that the metal electrodeposition and stripping processes are reversible.
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1,268
Concentration of PFHpA did not differ between mothers and cubs, while concentrations of PFOA, PFNA, PFDA, PFUnDA, PFDoDA, PFTrDA, PFHxS, and PFOS were higher in mothers than in their cubs.
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Allergic-like reactions to both nonionic icm and gbcm were extremely rare and when they did occur, they were mild acute reactions without significant clinical consequences despite the fact that an allergy preparation was not administered.
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1,270
When their neighborhoods were more segregated, the participants experienced small but statistically significant increases in systolic blood pressure.
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1,271
The treatment duration exerted no significant impact on symptom frequency (P > 0.05).
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Family adversity was not significantly associated with child externalizing behavior at high levels of positive peer relationships.
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1,273
Although birds have more neurons than expected from their small brain weights [5], their absolute neuron count is still lower compared to cortical neuron numbers of primates.
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1,274
The engraved lines are not the result of utilitarian activity, such as the cutting of meat or skins, but rather that of repeatedly and intentionally passing a robust pointed lithic tool (a pointed tool made of stone) into the rock to carve deep grooves.
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1,275
The technique does not need any information on how fast a target is moving or how far or close is the target.
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1,276
The time to renal flare did not differ between the aza and mmf patients, according to results published online ahead of print in the annals of rheumatic disease.
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Not all human tumors express all members of the src family, and that expression of yes and lyn differed among tumors.
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Chronic primary pain Chronic primary pain is pain in 1 or more anatomic regions that persists or recurs for longer than 3 months and is associated with significant emotional distress or significant functional disability (interference with activities of daily life and participation in social roles) and that cannot be better explained by another chronic pain condition.
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A delay of less than 120 days for women under 60 did not have a substantial negative effect on patient survival rates.
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1,280
Utilization of substance abuse treatment was significantly higher for the control group, but no differences were found in substance use or psychiatric symptoms.
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1,281
Pten-deficient metastatic pc cells fully depend on it.
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1,282
The incidence of lawn chemicals in the urine of pet dogs was widespread -- even among dogs in households where chemicals were not applied.
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1,283
The ingredient was not an accidental contaminant, cohen said.
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More studies are need to confirm and characterize the association between blood pressure and ad, they said.
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1,285
Dogs’ former training experience reduced the difference between their behaviour towards the owner and the familiar person in situations requiring obedience but it did not mask it totally.
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1,286
It is premature to issue a pco meant to apply to a general population of patients with cancer.
5
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1,287
From 1990 to 2014 average ozone concentrations in national parks were statistically indistinguishable from those of the 20 largest u.s.
6
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1,288
In contrast, long-term E 2 treatment resulted in the downregulation of ERα and p44/42 MAP kinase and upregulation of MMP-9 only, but no changes in c-ErbB2.
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1,289
The two groups did not differ significantly regarding disease-free and overall survival, and had similar rates of toxicities.
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1,290
The positive relationship between collision mortality and building size was greatest at large buildings in regions of low urbanization, locally extensive lawns, and low-density structures.
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The nutritional quality improved only somewhat between 1997 and 2010.
4
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1,292
There were no differences in abortion-related morbidity or adverse events in abortion procedures performed in an asc versus an office-based setting.
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1,293
Isoniazid preventive therapy works while people take it, but, in this setting, the effect was not enough to improve overall tb control.
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The opposite occurred in the non-south, with mandated desegregation positively associated with increases (although small) in the black teaching force.
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There are also subtle results that demonstrate the equivalence of such apparently different institutions as the standard sealed-bid auction, in which the auctioneer/seller sells the goods to the highest bidder for a price equal to his bid, and the Dutch auction, in which the auctioneer/seller begins by asking a high price and gradually lowers the price until"
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The data do not support the use of ramucirumab in first-line therapy for patients with gastric or gastroesophageal junction adenocarcinomas.
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1,297
The healthy calves were also infected by a related, although less harmful, parasite species: theileria mutans or theileria velifera.
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1,298
The orally administered compound kbu2046 inhibited metastasis, reduced bone destruction, and prolonged survival, without any evident toxicity.
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1,299
The effect of race on the experience of emotional and physical stress symptoms from racism is substantial.
6
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1,300
Spatial attention is not sufficient for attentional capture and awareness.
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1,301
Vaccines are neither necessary nor safe.
6
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1,302
Our dynamical results convincingly demonstrate that M67 could not have been the birth cluster of our solar system.«
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1,303
CONCLUSIONS:Contrary to popular belief, acute sauna use does not lead to a reduction, but to an increase in BP and HR with a consequent increase in myocardial oxygen consumption.
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1,304
GAT211 did not produce cardinal signs of direct CB 1 -receptor activation in the presence or absence of pathological pain.
6
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1,305
Even in species capable of perpetuate offspring through cloning, fertilization is still very much required to ensure the survival of the maximum number of healthy offspring, thus indicating that males have not become obsolete just yet.
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1,306
The necessary implication for public policy is that private ownership of a natural resource offers no assurance that the resource will be managed sustainably.
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1,307
There was not enough evidence to provide a guideline based on the grading of recommendation, assessment, development, and evaluation approach.
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1,308
The ratio between the relative risk and benefits of the available therapies for pain in pregnant women, such as NSAIDs and opioids, needs further careful investigation.
2
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1,309
The object really traveled 20 cm in the first 10th of a second.
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1,310
However, the process cannot be immediate and effortless, and can only be achieved within a market-wide strategic perspective.
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1,311
Non-emitting events occurring during a restricted period are never suspected by a distant observer.
6
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1,312
Remission was achieved by 54% (56 of 104) and 47% (47 of 99) of the patients given the 400-mg and 1200-mg dosages of rifaximin-EIR, respectively; these rates did not differ from those of placebo.
5
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1,313
Modern-day rumblings in the new madrid seismic zone are not echoes of the 1811 to 1812 quakes, however.
5
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1,314
There was evidence that the association was not significantly altered by stage of liver disease or the presence/absence of high alcohol consumption, high body mass index, type 2 diabetes mellitus, smoking, or hepatitis B and C viruses.
6
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1,315
They have a far more complex structure and composition than previously thought possible.
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1,316
Under OA the strength of this association was significantly reduced and there were male sperm performance rank changes under OA, such that the best males in current conditions are not necessarily best under OA.
6
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1,317
Total fat mass was not significantly different between the 4 beverage groups.
6
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1,318
Soreness rating increased from 3.6 ± 6.0 mm out of 100 mm at baseline to 47.4 ± 28.2 mm post-run and remained elevated at all time points with no differences between groups (p = 0.696).
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1,319
Sdf-1β had no effect on bmsc proliferation; however, sdf-1β significantly protected genetically engineered bmscs from h2o2-induced cell death through increasing autophagy and decreasing caspase-3-dependent apoptosis.
6
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1,320
Not all of the people buried there grew up locally.
4
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1,321
Wind and atmospheric turbulence did not significantly impact the system.2 llcd was even able to communicate through thin cirrus clouds.
4
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1,322
Although Telstar 18’s horizontal range will be nearly 10% shorter than Brazuca’s horizontal range for high-speed kicks, both Telstar 18 and Brazuca have similar knuckling effects due to nearly equal critical speeds and high-speed drag coefficients that differ by less than 10%.
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1,323
There was no difference in survival rates at five years between the group which had the most antibodies and the group which had none.
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1,324
While c-sections do indeed alter infant microbiomes, the health of these microbiomes is not simply dependent on how a child is delivered.
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1,325
The epa and dha composition increased in the fish oil groups, while total urinary anthocyanin metabolites did not differ between the groups.
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1,326
In contrast, among controls, those who were depressed rated fewer activities as important, but exhibited few significant differences in the performance of activities.
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1,327
Therefore, there was no evidence of the presence of microorganisms above background contamination from reagents in the placentas.
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1,328
Although active procrastinators procrastinate to the same degree as passive procrastinators, they are more similar to nonprocrastinators than to passive procrastinators in terms of purposive use of time, control of time, self-efficacy belief, coping styles, and outcomes including academic per..."
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It doesnat really matter whether youare socializing with a friend or facetiming a family member; when youare sleep-deprived, youare sleep-deprived, and that means youare more interested in your bed than you are in bonding with your squad.
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val
1,330
The CeOx layer does not affect the OER activity of the catalyst underneath but exhibits unique permselectivity, allowing the permeation of OH- and O2 through while preventing the diffusion of redox ions through the layer to function as a selective O2 -evolving electrode.
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1,331
No differences in expression of 13 genetic disorders were detected between purebred dogs and mixed-breed dogs (ie, hip dysplasia, hypo- and hyperadrenocorticism, cancers, lens luxation, and patellar luxation).
6
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1,332
It had a functional visual system, meaning that living hagfish eyes have been lost through millions of years of evolution, and these animals are not as primitively simple as we originally believed.
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1,333
Some declining north american bat species may be able to evolve enough resistance to the disease to persist, while other species appear less likely to do so.
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1,334
The CD4 count was 554 ± 169 cells/μl, and viral load was undetectable in all patients at the time of transplantation.
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1,335
Significant improvements in overall sexual function, most reproductive hormones and in psychological status were maintained over two years following surgery.
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1,336
Preeclampsia is not in fact a single disease caused solely by genetic factors.
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1,337
Despite many promising mechanisms to improve the referral process, rigorous evaluations of these improvements are needed.
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1,338
There was no significant between-group difference in the results, except for the papule count at week 4, which was -1.828 and 0.103 on the treated and nontreated sides, respectively.
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We found few significant changes in leaf traits when vertebrate herbivores were excluded in the short-term.
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1,340
A higher price did not guarantee better performance.
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Infant mortality rates have declined for babies born to white or black mothers -- although the rates for black babies are still more than double those for white infants.
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1,342
Peer comparison letters led to statistically meaningful, persistent decreases in quetiapine prescribing, with no detected negative effects on patients.
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The city continue to explore user engagement sites, among numerous other recommendations, but officials have not committed yet.
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