[DOC] [TLE] oncogene | biology | Britannica.com [PAR] An oncogene is a sequence of deoxyribonucleic acid (DNA) that has been 
altered or ... until being switched on to cause uncontrolled growth, its 
importance in cell ... cancer (in human genetic disease: Genetics of cancer) (in 
virus: Malignant... [DOC] [TLE] Ras subfamily - Wikipedia [PAR] Ras is a family of related proteins which is expressed in all animal cell lineages 
and organs. ... The 3 Ras genes in humans (HRas, KRas, and NRas) are the 
most common oncogenes in human cancer; mutations that permanently activate 
Ras are found in 20% to 25% of all human ..... Pathologic Basis of Disease 8th ed
. p. [DOC] [TLE] final exam lecture notes [PAR] Detecting Human Genetic Variations: Screening for Human Diseases ... Cystic 
fibrosis is a genetic disease which results in unusually thick and dry mucus in the 
..... At least three tumor suppressor genes and one oncogene must be mutated in 
..... MyoD1 is the first gene switched on and it codes for a helix-loop-helix type... [DOC] [TLE] Harvey Ras oncogene - Genes and Disease - NCBI Bookshelf [PAR] Ras is one such oncogene product that is found on chromosome 11. ... Ras is not 
activated and so the pathway that results in cell growth is not initiated. In about 30
% of human cancers, Ras is mutated so that it is permanently switched on,... [DOC] [TLE] Simple Mutations of Proto-oncogenes in Human Cancers - NCBI [PAR] And, if so, are these genes involved in the generation of human cancers? ... 
retroviruses that cause relatively uncommon human diseases, especially a .... for 
proto-oncogenes that might be switched on by proviral insertions in another and
... [DOC] [TLE] The Molecular Basis of Cancer-Cell Behavior - Molecular Biology of ... [PAR] Oncogenes and tumor suppressorsand the mutations that affect themare ... 
The same kinds of effects on cell behavior can result from mutations in either 
class of ... Chart of the major signaling pathways relevant to cancer in human 
cells, ..... are selectively switched on in cancer cells that have become highly 
malignant. [DOC] [TLE] Genetic complexity in sickle cell disease [PAR] Aug 19, 2008 ... Sickle cell disease (SCD) was the first human monogenic disorder to be ... and 
this results in anemia (due to destruction of the red cells) and intermittent ... down 
and the -gene is switched on so that adults mainly produce HbA (22). ... in 
patients with SCD (rs4671393) lies in the intron of an oncogene,... [DOC] [TLE] NOVA | Transcripts | Ghost in Your Genes | PBS [PAR] Oct 16, 2007 ... NEWS AUDIO: The Human Genome Project will be seen as the outstanding ... 
hoped to find the genetic cause and cure for every disease. .... is not their genes, 
but how these genes are switched on or off by epigenetics. .... And there are other 
genes, called oncogenes, that stimulate the growth of tumors. [DOC] [TLE] Mechanisms of Disease: oncogene addiction[mdash]a ... - Nature [PAR] Table 2 Examples of oncogene addiction: studies in human cancer cell lines. ... 
tissue under conditions in which the oncogene can be switched on or off (Table 1
). ... As a result of the efficacy of the RNAi method for inhibiting the expression of... [DOC] [TLE] Learning About Severe Combined Immunodeficiency (SCID ... [PAR] Although a rare disease, SCID has been extensively studied over the past 
several ... studies by physicians at the National Human Genome Research 
Institute. .... cell's chromosome that switched on a cancer-causing gene (
oncogene). Today... [DOC] [TLE] The Biology of Cancer [PAR] Evidence accumulated to support the idea that cancer was the result of .... Genes 
known as proto-oncogenes can be switched on to produce proteins .... Since 
humans have two copies of each gene, Knudson hypothesized that ..... The 
altered cell and its descendants grow and divide too often, a condition called 
hyperplasia. [DOC] [TLE] N-myc Expression Switched Off and Class I Human Leukocyte ... [PAR] Antigen Expression Switched On after Somatic Cell. Fusion of Neuroblastoma 
Cells ... tion of the N-myc oncogene,

Question: When an oncogene is "switched on", this disease results in humans
Answer: cancer