[DOC] [TLE] Simple Facts about Sickle Cell  IHTC [PAR] Sickle cell disease is the most common hereditary hematologic disorder in the 
world. ... Sickle cell disease affects about 1 in 400 African-Americans. ... In sickle 
hemoglobin, the alpha chains are normal, but the beta chain has a substitution of
... [DOC] [TLE] Inherited Disorders of Hemoglobin - Disease Control Priorities in ... [PAR] Although these disorders are most frequent in tropical regions, they are now 
encountered ... Page 1 of 102 ... the inherited hemoglobin disorders are the 
commonest diseases attributable to .... Every severely affected population in the 
world has a few common mutations ...... Sub-Saharan Africa, 138, 021, 0, 012, 
0, 1050. [DOC] [TLE] Frequently Asked Questions | Sickle Cell Anemia | Health & Senior ... [PAR] Your hemoglobin type is inherited through family genes. ... Sickle cell trait is not a 
disease and usually does not affect one's health, but ... If you inherit only one 
sickle gene, you have sickle cell trait and will not develop the disease. ... in every 
400 African-American births, and approximately 1 in 12 African Americans carry 
the... [DOC] [TLE] hereditary diseases [PAR] The mutation affects the protein within the hemoglobin of the red blood cell. ... 
One in every 400 African-Americans is affected with the gene inherited from each 
... The parent does not have to have the Sickle Cell disease in order pass the trait
... [DOC] [TLE] Genetic Screening and Recessive Inheritance [PAR] Recessive genetic diseases are those that result when both copies of a gene that 
a ... Everyone carries a few of these altered genes, and each ethnic group has 
certain ... Sickle cell anemia is an inherited hemoglobin disorder that can lead to 
blocked ... of African descent and affects about one in 400 African-Americans. [DOC] [TLE] William E. Proudford Sickle Cell Fund  About Sickle Cell Disease [PAR] A person with the trait carries one abnormal hemoglobin gene inherited from one 
... Sickle cell disease affects people of many nationalities including Italians, Latin 
... cell trait, and 1 out of 400-500 African American newborns has the disease. [DOC] [TLE] sickle cell disease facts, information, pictures | Encyclopedia.com ... [PAR] Sickle cell disease describes a group of inherited blood disorders characterized 
by ... The red blood cells of affected individuals contain a predominance of a 
structural ... This results in chronic anemia characterized by low levels of 
hemoglobin and ... Today, approximately one in 12 African Americans has sickle 
cell trait. [DOC] [TLE] ETHNIC DIFFERENCES CAN PLAY A BIG ROLE IN MEDICAL ... [PAR] Oct 4, 1991 ... The 23- year-old has beta thalassemia, a blood disorder that afflicts two of her ... 
of diseases that affect specific populations, ranging from hemoglobin disorders to 
... genetic and ethnic connections to disease may become clearer. ... disorder is 
sickle-cell disease, which affects 1 in 400 African Americans. [DOC] [TLE] Exceptions to Mendel - Biology @ IUPUI [PAR] I Review: Genetically Inherited Human Disorders: 1. Autosomal recessive ... C. 
Sickle-cell disease: The most common inherited disease of African-Americans (1:
400 affected). Homozygous recessives (ss) make abnormal form of hemoglobin 
that ... In this case, if one parent has the trait, the offspring will have a 50% 
chance... [DOC] [TLE] Common Genetic Disorders in African Americans | LIVESTRONG.COM [PAR] Oct 25, 2015 ... Some genetic diseases, especially sickle cell anemia, occur at a ... According to 
Thompson & Thompson: Genetics in Medicine every 1 in 11 African Americans 
carry the ... Carriers have one defective copy of the gene, but since the other ... 
beta-thalassemia is also a blood disorder affecting hemoglobin. [DOC] [TLE] Printer Friendly Version - SickleCellTrait.org [PAR] Sickle cell trait (SCT) is an inherited condition that affects the hemoglobin in red 
blood cells. ... About 1 in 400 African Americans have sickle cell disease. [DOC] [TLE] Printer Friendly Version - SickleCellTrait.org [PAR] If one parent has sickle cell trait and the other parent has normal hemoglobin, the 
... Sickle cell trait (SCT) is an inherited condition that affects the hemoglobin in 
red blood cells

Question: About 1 in 400 African-Americans has this hereditary disease affecting the hemoglobin
Answer: sickle-cell anemia