[DOC] [TLE] Skin Cream Seems to Reverse Some Harmful Effects of Sun ... [PAR] Jan 22, 1988 ... LEAD: A small study has found that a prescription cream containing a chemical ... 
of reversing some of the damaging effects that sunlight has on skin. ... that a drug 
has been shown to actually turn back sun-caused skin damage. ... as a 
prescription anti-acne drug, reversed some of the sun damage after four... [DOC] [TLE] Health - Personal Health - NYTimes.com [PAR] LEAD: As summer approaches and the sun shines brightly on barely clothed ... 
Published: June 16, 1988 ... effect under study is that Retin-A, which can halt or 
reverse the ... used since the late 1960's as a physician-prescribed topical cream 
or gel for acne. ... and found that tretinoin caused most the premalignant lesions 
to... [DOC] [TLE] Articles about Retin A - tribunedigital-orlandosentinel [PAR] A drug used to smooth out wrinkles caused by years of exposure to the sun ... a 
prescription cream recently approved by the Food and Drug Administration for ... 
it promoted Retin-A, an acne drug also found to reduce wrinkles, the company 
said. ... a form of vitamin A. As a cream it can be applied to photoaged skin to 
reverse... [DOC] [TLE] Acne Medication May Reduce Wrinkles, Too - tribunedigital ... [PAR] Dec 2, 1989 ... I`ve spent many a hard-earned dollar on creams that. ... of collagen and new 
vessels, reversing the effects of aging caused by sunlight. ... Whenever any side 
effects are discovered, the medication must be ... January 22, 1988. [DOC] [TLE] Sun damage to skin need not be permanent - The San Diego Union ... [PAR] Apr 15, 2013 ... However, we hate its accumulative effects  the wrinkling, brown spots, rough ... 
acid (the active ingredient in the prescription creams) it is less potent. ... It can 
help improve and even reverse some sun damage, Mauricio said. .... can worsen 
acne or cause temporary tiny white bumps (milia) on treated skin. [DOC] [TLE] ACNE DRUG SIDE EFFECT NEW AGE IN SKIN CARE? - The ... [PAR] Jan 22, 1988 ... The treatment, using a topical cream called tretinoin, softened rough ... The 
research was designed to look at the effects of sun on the skin, the cause of 
nearly all wrinkling, ... The researchers found that 30 percent of tretinoin-treated 
forearms ... And I have prescribed the drug for wrinkles," said Dr. Philip G. [DOC] [TLE] Effective Management of Fine Lines and Wrinkles . | The Dermatologist [PAR] As dermatologists, we prescribe these products to enhance results obtained from 
in-office ... In more advanced cases, the cumulative effects of the sun induce ac-
tinic ... tretinoin to treat acne also saw a softening of periorbital wrinkles.11 These 
... et al in 1988.12 In this trial, patients used 0.1% tretinoin cream once daily for 4
... [DOC] [TLE] The Pennsylvania Center for the Book - Retin A [PAR] Retin-A, a skin cream developed in 1967 by Dr. Albert Kligman, was initially used 
to treat acne but would later be discovered as a solution to wrinkles and aging. .... 
Sun damage also causes two proteins found in skin, collagen and elastin to be 
produced ... Fortunately, Retin-A can reverse the negative effects of photoaging. [DOC] [TLE] Topical tretinoin: its use in daily practice to reverse photoageing [PAR] The effect of o-1 % tretinoin cream for the treatment of photoageing was ... 
although coarse wrinkling, brown spots, tactile roughness and overall skin ... The 
majority of lentigines and sun-induced freckles showed some reduction ... 
Tretinoin (all-rra5-retinoic acid) has been used topically for the treatment of 
acne for the last. [DOC] [TLE] Retinoids: From Acne to Wrinkle Treatment - Skin and Beauty Center ... [PAR] Aug 5, 2010 ... Retinoids, drugs derived from vitamin A, were first used to treat acne. ... today, 
with prescription products yielding far greater results than beauty brands. ... of the 
skin from sun exposure) and were soon used as a wrinkle treatment. ... Generic 
isotretinoin may

Question: In 1988 this prescription acne cream was found to reverse the effects of sun-induced wrinkles
Answer: Retin-A