Claim: Joyce Culpeper was born to Sir Ralph Leigh and his second wife, Isabel Worsley, in 1480, was married twice and had two sons and three daughters.
Evidence: Jocasta "Joyce" Culpeper, of Oxon Hoath (c. 1480 – c. 1528) was the mother of Catherine Howard, the fifth wife and Queen consort of King Henry VIII. Joyce Culpeper, born about 1480, was the daughter of Sir Richard Culpeper (d. 4 October 1484) and his second wife, Isabel Worsley (born c. 1460 – 18 April 1527), the daughter of Otewell Worsley of Southwark, Surrey, by Rose Trevor. 
c. 1480 Howard (by marriage) Ralph Leigh
Lord Edmund Howard Sir Richard Culpeper Isabel Worsley