Claim: ADP-ribosylation factor 1 (ARF1), a member of the human ARF gene family, encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin (an AB5 multimeric protein complex).
Evidence: ADP-ribosylation factor 1 (ARF1) is a member of the human ARF gene family. The family members encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking as activators of phospholipase D. Cholera toxin (also known as choleragen and sometimes abbreviated to CTX, Ctx or CT) is AB5 multimeric protein complex secreted by the bacterium Vibrio cholerae.