Claim: Rosal-Dorfman disease is a rare disorder characterized by abundant histiocytes (vertebrate cells that are derived from bone marrow by multiplication of stem cells) for which surgery, radiation, or chemotherapy are the only treatments.
Evidence: Rosai–Dorfman disease, also known as sinus histiocytosis with massive lymphadenopathy or sometimes as Destombes–Rosai–Dorfman disease, is a rare disorder of unknown cause that is characterized by abundant histiocytes in the lymph nodes or other locations throughout the body. A histiocyte is a vertebrate cell that is part of the mononuclear phagocyte system (also known as the reticuloendothelial system or lymphoreticular system). Histiocytes are derived from the bone marrow by multiplication from a stem cell. Therapeutic options include surgery, radiation therapy, and chemotherapy.