Claim: The DAZL gene encodes potential RNA binding proteins localized to the nucleus and cytoplasm of fetal germ cells, with mutations being linked to severe spermatogenic failure and infertility in males.
Evidence: The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. Mutations in this gene have been linked to severe spermatogenic failure and infertility in males.