Claim: Hormone replacement therapy resulted in 4000 cases of breast cancer from estrogen alone, and 43 cases from Estradiol.
Evidence: It is an estrogen and is used mainly in menopausal hormone therapy and to treat low sex hormone levels in women. Worldwide epidemiological evidence on breast cancer risk with menopausal hormone therapy (CGHFBC, 2019) Estradiol 346 1580 435