Claim: Pentraxin-related protein PTX3, also known as TNF-inducible gene 14 protein, is a member of the pentraxin superfamily or phylogenetically conserved humoral mediators of innate immunity, a protein that in humans is encoded by the PTX3 gene.
Evidence: Pentraxin-related protein PTX3 also known as TNF-inducible gene 14 protein (TSG-14) is a protein that in humans is encoded by the PTX3 gene. Pentraxin 3 (ptx3) is a member of the pentraxin superfamily. Under these conditions, PTX3 is a rapid marker for primary local activation of innate immunity and inflammation.