Claim: Toxic shock syndrome toxin 1 is a water-soluble protein toxin, heat-resistant, and can be boiled for more than an hour without any direct effect on its function.
Evidence: Even though TSST-1 consists of several hydrophobic amino acids, this protein is highly soluble in water. It has been shown that TSST-1 can be boiled for more than an hour without any presence of denaturation or direct effect on its function. TSST-1 is resistant to heat and proteolysis. Toxic shock syndrome toxin 1 (TSST-1), a prototype superantigen secreted by a Staphylococcus aureus bacterium strain in susceptible hosts, acts on the vascular system by causing inflammation, fever, and shock.