Claim: Recently, the proteasome, a protein complex which form a pivotal component of the ubiquitin–proteasome system, is studied more for the development of novel diagnostic markers and strategies.
Evidence: Proteasomes are protein complexes which degrade unneeded or damaged proteins by proteolysis, a chemical reaction that breaks peptide bonds. More recently, more effort has been made to consider the proteasome for the development of novel diagnostic markers and strategies. The proteasomes form a pivotal component for the ubiquitin–proteasome system (UPS) and corresponding cellular Protein Quality Control (PQC).