Claim: RUVBL2 encodes the second human homologue of the bacterial RuvB gene, an essential protein found in all organisms,  and is physically linked to the CGB/LHB gene cluster.
Evidence: This gene encodes the second human homologue of the bacterial RuvB gene. This gene is physically linked to the CGB/LHB gene cluster on chromosome 19q13.3, and is very close (55 nt) to the LHB gene, in the opposite orientation. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair.