Claim: Deficiency of TCF2 cause abnormal maternal-Zygote transition and early embryogenesis failure and mutation of TCF2 that disrupts normal function has been identified as the cause of MODY5 (Maturity-Onset of Diabetes, Type 5).
Evidence: Deficiency of TCF2 cause abnormal maternal-Zygote transition and early embryogenesis failure. Mutation of TCF2 that disrupts normal function has been identified as the cause of MODY5 (Maturity-Onset of Diabetes, Type 5).