Claim: Among the proteins encoded by the Zaire ebolavirus, which caused hemorrhagic fever in humans and other primates, VP 30 or hexameric zinc-finger protein is a transcriptional activator while VP 35 or polymerase cofactor suppresses innate immunity by binding RNA.
Evidence: It encodes seven structural proteins: nucleoprotein (NP), polymerase cofactor (VP35), (VP40), GP, transcription activator (VP30), VP24, and RNA-dependent RNA polymerase (L). Four of the six known ebolaviruses, including EBOV, cause a severe and often fatal hemorrhagic fever in humans and other mammals, known as Ebola virus disease (EVD). VP30 Hexameric zinc-finger protein VP30 Transcriptional activator. VP35 Polymerase cofactor VP35 Polymerase cofactor; suppresses innate immunity by binding RNA.