Claim: MAP2K4, an enzyme in humans, has not been sufficiently studied to determine whether it has a role in response to environmental stresses on mitogenic stimuli.
Evidence: Dual-specificity mitogen-activated protein kinase kinase 4 is an enzyme that in humans is encoded by the MAP2K4 gene. MAP2K4 phosphorylates MAP kinases in response to various environmental stresses or mitogenic stimuli. In chemistry, phosphorylation (a phosphate group is added to a molecule) of a molecule is the attachment of a phosphoryl group. Together with its counterpart, dephosphorylation, (to lose a molecule) it is critical for many cellular processes in biology.