Claim: MAPKAPK2 encodes a member of the Ser/Thr protein kinase family, and is regulated through direct phosphorylation by p38 MAP kinase (are responsive to stress stimuli, such as cytokines, ultraviolet irradiation, heat shock, and osmotic shock).
Evidence: This gene encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. p38 mitogen-activated protein kinases are a class of mitogen-activated protein kinases (MAPKs) that are responsive to stress stimuli, such as cytokines, ultraviolet irradiation, heat shock, and osmotic shock, and are involved in cell differentiation, apoptosis and autophagy.