Claim: PAC1 is a membrane-associated protein that shares significant homology with members of the G-protein coupled class B glucagon/secretin receptor family, and is expressed in the adrenal medulla, pancreatic acini, uterus, myenteric plexus and brain.
Evidence: Pituitary adenylate cyclase-activating polypeptide type I receptor also known as PAC1, is a protein that in humans is encoded by the ADCYAP1R1 gene. PAC1 is a membrane-associated protein and shares significant homology with members of the G-protein coupled class B glucagon/secretin receptor family. PAC1 is expressed in the adrenal medulla, pancreatic acini, uterus, myenteric plexus and brain.