Claim: HSD3B2 is expressed principally in steroidogenic tissues and is essential for steroid hormone production, although one notable exception is the placenta, where HSD3B1 is critical for progesterone production by this tissue.
Evidence: A notable exception is the placenta, where HSD3B1 is critical for progesterone production by this tissue. It is expressed principally in steroidogenic tissues and is essential for steroid hormone production.