Claim: E2F3 plays a crucial role in the control of the cell cycle, and is a protein, a biomolecules consisting of one or more chains of amino acid residues.
Evidence: Transcription factor E2F3 is a protein that in humans is encoded by the E2F3 gene. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F proteins contain several evolutionally conserved domains found in most members of the family.