Claim: CDC6 homolog is a protein (chains of amino acids), it localizes in the cell nucleus during cell cycle and is essential in DNA replication.
Evidence: Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific 3D structure that determines its activity. It localizes in the cell nucleus during cell cycle phase G1, but translocates to the cytoplasm at the start of S phase. Cell division control protein 6 homolog is a protein that in humans is encoded by the CDC6 gene. This protein functions as a regulator at the early steps of DNA replication.