Claim: ADAM12 gene encodes a member of the a disintegrin and metalloprotease protein family, are membrane-anchored proteins and have two alternatively spliced transcripts.
Evidence: Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene has two alternatively spliced transcripts: a shorter secreted form and a longer membrane-bound form. This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family.