Claim: TRAF proteins, one of the components of a multiple protein complex, are associated with, and mediate signal transduction from members of the TNF receptor superfamily.
Evidence: This protein is one of the components of a multiple protein complex which binds to tumor necrosis factor (TNF) receptor cytoplasmic domains and mediates TNF-induced activation. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily.