Claim: Mutations with the Ryanodine receptor 2 is linked to catecholaminergic polymorphic ventricular tachycardia, an inherited genetic disorder which functions in the myocardium.
Evidence: Mutations in the RYR2 gene are associated with catecholaminergic polymorphic ventricular tachycardia and arrhythmogenic right ventricular dysplasia. Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an inherited genetic disorder that predisposes those affected to potentially life-threatening abnormal heart rhythms or arrhythmias. Cardiac muscle (also called heart muscle or myocardium) is one of three types of vertebrate muscles, with the other two being skeletal and smooth muscles.