Claim: Imatinib is used as a curative for cancer treatment called chemo or chemotherapy and is highly bioavailable and is metabolized in the liver.
Evidence: Imatinib, sold under the brand name Gleevec among others, is an oral chemotherapy medication used to treat cancer. Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is a type of cancer treatment that uses one or more anti-cancer drugs (chemotherapeutic agents) as part of a standardized chemotherapy regimen. Imatinib is rapidly absorbed when given by mouth, and is highly bioavailable: 98% of an oral dose reaches the bloodstream. Metabolism of imatinib occurs in the liver and is mediated by several isozymes of the cytochrome P450 system, including CYP3A4 and, to a lesser extent, CYP1A2, CYP2D6, CYP2C9, and CYP2C19.