Claim: The deterministic effect of ionizing radiation on human health can lead to acute radiation syndrome which occurs upon high doses and high dose rates.
Evidence: This contrasts with the deterministic effects of acute radiation syndrome which increase in severity with dose above a threshold. Acute radiation syndrome (ARS), also known as radiation sickness or radiation poisoning, is a collection of health effects that are caused by being exposed to high amounts of ionizing radiation, in a short period of time. At high doses, this causes DNA damage that may be irreparable. ARS is caused by exposure to a large dose of ionizing radiation (> ~0.1 Gy) over a short period of time (> ~0.1 Gy/h). Exposure to high doses of radiation cause DNA damage, later creating serious and even lethal chromosomal aberrations if left unrepaired. Ingestion of radioactive materials caused many radiation-induced cancers in the 1930s, but no one was exposed to high enough doses at high enough rates to bring on ARS.