Claim: Mutations with the Ryanodine receptor 2 is linked to catecholaminergic polymorphic ventricular tachycardia which functions in the myocardium.
Evidence: Mutations in the RYR2 gene are associated with catecholaminergic polymorphic ventricular tachycardia and arrhythmogenic right ventricular dysplasia. Normal (wild type) RyR2 functions primarily in the myocardium (heart muscle).