Claim: Nucleoporin 153, a protein which in humans is encoded by the NUP153 gene, is an essential component of the basket of nuclear pore complexes (NPCs- which span the nuclear envelope, which is the double membrane surrounding the eukaryotic cell nucleus) in vertebrates, and acts as the docking site of Karyopherin.
Evidence: Nucleoporin 153 (Nup153) is a protein which in humans is encoded by the NUP153 gene. A nuclear pore is a part of a large complex of proteins, known as a nuclear pore complex that spans the nuclear envelope, which is the double membrane surrounding the eukaryotic cell nucleus. It is an essential component of the basket of nuclear pore complexes (NPCs) in vertebrates, and required for the anchoring of NPCs. It also acts as the docking site of an importing karyopherin.