Druvith/transformed_medDataset huggingface dataset:
What to do for What I need to know about Kidney Failure and How Its Treated ? 
 - Kidney failure means your kidneys no longer filter your blood well enough to keep you healthy.  - The treatments for kidney failure are      - hemodialysis    - peritoneal dialysis    - a kidney transplant    - conservative management    - Hemodialysis uses a machine to filter your blood when your kidneys are too sick to filter any more.  - Peritoneal dialysis uses the lining of your belly to filter your blood inside your body.  - A kidney transplant places a healthy kidney from another person into your body.  - Conservative management means your doctors take care of you without dialysis or a transplant. The doctors may give you medicines that make you feel more comfortable.  - All dialysis and transplant centers have a dietitian. The dietitian helps people with kidney failure learn about healthy food choices.
What is (are) What I need to know about Kidney Failure and How Its Treated ? 
 You and your doctor will work together to choose a treatment that's best for you. The publications of the NIDDK Kidney Failure Series can help you learn about the specific issues you will face.
                
Booklets
                
- What I need to know about Kidney Failure and How its Treated  - Treatment Methods for Kidney Failure: Hemodialysis  - Treatment Methods for Kidney Failure: Peritoneal Dialysis  - Treatment Methods for Kidney Failure: Kidney Transplantation  - Kidney Failure: Eat Right to Feel Right on Hemodialysis
                
Fact Sheets
                
- Kidney Failure: What to Expect  - Vascular Access for Hemodialysis  - Hemodialysis Dose and Adequacy  - Peritoneal Dialysis Dose and Adequacy  - Amyloidosis and Kidney Disease  - Anemia in Chronic Kidney Disease  - Chronic Kidney Disease-Mineral and Bone Disorder  - Financial Help for Treatment of Kidney Failure
                
Learning as much as you can about your treatment will help make you an important member of your health care team.
                

                

                
This content is provided as a service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the National Institutes of Health. The NIDDK translates and disseminates research findings through its clearinghouses and education programs to increase knowledge and understanding about health and disease among patients, health professionals, and the public. Content produced by the NIDDK is carefully reviewed by NIDDK scientists and other experts.
                
The NIDDK would like to thank: Neil R. Powe, M.D., M.P.H., M.B.A., University of California, San Francisco; Delphine Tuot, M.D.C.M., M.A.S., University of California, San Francisco; Vicki McClelland and Brian Testerman, both of the Free Medical Clinic of Northern Shenandoah Valley in Winchester, VA
                
This information is not copyrighted. The NIDDK encourages people to share this content freely.
                

                

                
September 2014
What is (are) Peyronie's Disease ? 
 Peyronies disease is a disorder in which scar tissue, called a plaque, forms in the penisthe male organ used for urination and sex. The plaque builds up inside the tissues of a thick, elastic membrane called the tunica albuginea. The most common area for the plaque is on the top or bottom of the penis. As the plaque builds up, the penis will curve or bend, which can cause painful erections. Curves in the penis can make sexual intercourse painful, difficult, or impossible. Peyronies disease begins with inflammation, or swelling, which can become a hard scar.
                
The plaque that develops in Peyronies disease is not the same plaque that can develop in a persons arteries. The plaque seen in Peyronies disease is benign, or noncancerous, and is not a tumor. Peyronies disease is not contagious or caused by any known transmittable disease.
                
Early researchers thought Peyronies disease was a form of impotence, now called erectile dysfunction (ED). ED happens when a man is unable to achieve or keep an erection firm enough for sexual intercourse. Some men with Peyronies disease may have ED. Usually men with Peyronies disease are referred to a urologista doctor who specializes in sexual and urinary problems.
What causes Peyronie's Disease ? 
 Medical experts do not know the exact cause of Peyronies disease. Many believe that Peyronies disease may be the result of
                
- acute injury to the penis  - chronic, or repeated, injury to the penis  - autoimmune diseasea disorder in which the bodys immune system attacks the bodys own cells and organs
                
Injury to the Penis
                
Medical experts believe that hitting or bending the penis may injure the tissues inside. A man may injure the penis during sex, athletic activity, or an accident. Injury ruptures blood vessels, which leads to bleeding and swelling inside the layers of the tunica albuginea. Swelling inside the penis will block blood flow through the layers of tissue inside the penis. When the blood cant flow normally, clots can form and trap immune system cells. As the injury heals, the immune system cells may release substances that lead to the formation of too much scar tissue. The scar tissue builds up and forms a plaque inside the penis. The plaque reduces the elasticity of tissues and flexibility of the penis during erection, leading to curvature. The plaque may further harden because of calcificationthe process in which calcium builds up in body tissue.
                
Autoimmune Disease
                
Some medical experts believe that Peyronies disease may be part of an autoimmune disease. Normally, the immune system is the bodys way of protecting itself from infection by identifying and destroying bacteria, viruses, and other potentially harmful foreign substances. Men who have autoimmune diseases may develop Peyronies disease when the immune system attacks cells in the penis. This can lead to inflammation in the penis and can cause scarring. Medical experts do not know what causes autoimmune diseases. Some of the autoimmune diseases associated with Peyronies disease affect connective tissues. Connective tissue is specialized tissue that supports, joins, or separates different types of tissues and organs of the body.
How many people are affected by Peyronie's Disease ? 
 Researchers estimate that Peyronies disease may affect 1 to 23 percent of men between 40 and 70 years of age.1 However, the actual occurrence of Peyronies disease may be higher due to mens embarrassment and health care providers limited reporting.1 The disease is rare in young men, although it has been reported in men in their 30s.1 The chance of developing Peyronies disease increases with age.
What are the symptoms of Peyronie's Disease ? 
 The signs and symptoms of Peyronies disease may include
                
- hard lumps on one or more sides of the penis  - pain during sexual intercourse or during an erection  - a curve in the penis either with or without an erection  - narrowing or shortening of the penis  - ED
                
Symptoms of Peyronies disease range from mild to severe. Symptoms may develop slowly or appear quickly. In many cases, the pain decreases over time, although the curve in the penis may remain. In milder cases, symptoms may go away without causing a permanent curve.
What are the complications of Peyronie's Disease ? 
 Complications of Peyronies disease may include
                
- the inability to have sexual intercourse  - ED  - anxiety, or stress, about sexual abilities or the appearance of the penis  - stress on a relationship with a sexual partner  - problems fathering a child because intercourse is difficult
How to diagnose Peyronie's Disease ? 
 A urologist diagnoses Peyronies disease based on
                
- a medical and family history  - a physical exam  - imaging tests
                
Medical and Family History
                
Taking a medical and family history is one of the first things a urologist may do to help diagnose Peyronies disease. He or she will ask the man to provide a medical and family history, which may include the following questions:
                
- What is the mans ability to have an erection?  - What are the problems with sexual intercourse?  - When did the symptoms begin?  - What is the family medical history?  - What medications is the man taking?  - What other symptoms is the man experiencing?  - What other medical conditions does the man have?
                
Physical Exam
                
A physical exam may help diagnose Peyronies disease. During a physical exam, a urologist usually examines the mans body, including the penis.
                
A urologist can usually feel the plaque in the penis with or without an erection. Sometimes the urologist will need to examine the penis during an erection. The urologist will give the man an injectable medication to cause an erection.
                
Imaging Tests
                
To help pinpoint the location of the plaque buildup inside the penis, a urologist may perform
                
- ultrasound of the penis  - an x ray of the penis
                
For both tests, a specially trained technician performs the procedure in a health care providers office, an outpatient center, or a hospital, and a radiologista doctor who specializes in medical imaginginterprets the images. The patient does not need anesthesia.
                
Ultrasound. Ultrasound uses a device, called a transducer, that bounces safe, painless sound waves off organs to create an image of their structure.
                
X ray. An x ray is a picture created by using radiation and recorded on film or on a computer. The amount of radiation used is small. The man will lie on a table or stand during the x ray, and the technician may ask the man to change positions for additional pictures.
How to prevent Peyronie's Disease ? 
 Researchers do not know how to prevent Peyronies disease.
What to do for Peyronie's Disease ? 
 Researchers have not found that eating, diet, and nutrition play a role in causing or preventing Peyronies disease.
What to do for Peyronie's Disease ? 
 - Peyronies disease is a disorder in which scar tissue, called a plaque, forms in the penisthe male organ used for urination and sex.  - Medical experts do not know the exact cause of Peyronies disease. Many believe that Peyronies disease may be the result of      - acute injury to the penis    - chronic, or repeated, injury to the penis    - autoimmune diseasea disorder in which the bodys immune system attacks the bodys own cells and organs    - The following factors may increase a mans chance of developing Peyronies disease:      - vigorous sexual or nonsexual activities that cause microscopic injury to the penis    - certain connective tissue and autoimmune disorders    - a family history of Peyronies disease    - aging    - The signs and symptoms of Peyronies disease may include      - hard lumps on one or more sides of the penis    - pain during sexual intercourse or during an erection    - a curve in the penis either with or without an erection    - narrowing or shortening of the penis    - erectile dysfunction (ED)    - Complications of Peyronies disease may include      - the inability to have sexual intercourse    - ED    - anxiety, or stress, about sexual abilities or the appearance of the penis    - stress on a relationship with a sexual partner    - problems fathering a child because intercourse is difficult    - A urologist diagnoses Peyronies disease based on      - a medical and family history    - a physical exam    - imaging tests    - A urologist may treat Peyronies disease with nonsurgical treatments or surgery.  - Researchers do not know how to prevent Peyronies disease.
What is (are) Gastritis ? 
 Gastritis is a condition in which the stomachliningknown as the mucosais inflamed, or swollen. The stomach lining contains glands that produce stomach acid and an enzyme called pepsin. The stomach acid breaks down food and pepsin digests protein. A thick layer of mucus coats the stomach lining and helps prevent the acidic digestive juice from dissolving the stomach tissue. When the stomach lining is inflamed, it produces less acid and fewer enzymes. However, the stomach lining also produces less mucus and other substances that normally protect the stomach lining from acidic digestive juice.
                
Gastritis may be acute or chronic:
                
- Acute gastritis starts suddenly and lasts for a short time.  - Chronic gastritis is long lasting. If chronic gastritis is not treated, it may last for years or even a lifetime.
                
Gastritis can be erosive or nonerosive:
                
- Erosive gastritis can cause the stomach lining to wear away, causing erosionsshallow breaks in the stomach liningor ulcersdeep sores in the stomach lining.  - Nonerosive gastritis causes inflammation in the stomach lining; however, erosions or ulcers do not accompany nonerosive gastritis.
                
A health care provider may refer a person with gastritis to a gastroenterologista doctor who specializes in digestive diseases.
What are the symptoms of Gastritis ? 
 Some people who have gastritis have pain or discomfort in the upper part of the abdomenthe area between the chest and hips. However, many people with gastritis do not have any signs and symptoms. The relationship between gastritis and a person's symptoms is not clear. The term gastritis is sometimes mistakenly used to describe any symptoms of pain or discomfort in the upper abdomen.
                
When symptoms are present, they may include
                
- upper abdominal discomfort or pain  - nausea  - vomiting
                

                
Seek Help for Symptoms of Bleeding in the Stomach   Erosive gastritis may cause ulcers or erosions in the stomach lining that can bleed. Signs and symptoms of bleeding in the stomach include   - shortness of breath   - dizziness or feeling faint   - red blood in vomit   - black, tarry stools   - red blood in the stool   - weakness   - paleness    A person with any signs or symptoms of bleeding in the stomach should call or see a health care provider right away.   More information is provided in the NIDDK health topic, Bleeding in the Digestive Tract.
What are the symptoms of Gastritis ? 
 Erosive gastritis may cause ulcers or erosions in the stomach lining that can bleed. Signs and symptoms of bleeding in the stomach include
                
- shortness of breath  - dizziness or feeling faint  - red blood in vomit  - black, tarry stools  - red blood in the stool  - weakness  - paleness
                
A person with any signs or symptoms of bleeding in the stomach should call or see a health care provider right away.
                
More information is provided in the NIDDK health topic, Bleeding in the Digestive Tract.
What are the complications of Gastritis ? 
 The complications of chronic gastritis may include
                
- peptic ulcers. Peptic ulcers are sores involving the lining of the stomach or duodenum, the first part of the small intestine. NSAID use and H. pylori gastritis increase the chance of developing peptic ulcers.  - atrophic gastritis. Atrophic gastritis happens when chronic inflammation of the stomach lining causes the loss of the stomach lining and glands. Chronic gastritis can progress to atrophic gastritis.  - anemia. Erosive gastritis can cause chronic bleeding in the stomach, and the blood loss can lead to anemia. Anemia is a condition in which red blood cells are fewer or smaller than normal, which prevents the body's cells from getting enough oxygen. Red blood cells contain hemoglobin, an iron-rich protein that gives blood its red color and enables the red blood cells to transport oxygen from the lungs to the tissues of the body. Research suggests that H. pylori gastritis and autoimmune atrophic gastritis can interfere with the body's ability to absorb iron from food, which may also cause anemia. Read more about anemia at www.nhlbi.nih.gov.  - vitamin B12 deficiency and pernicious anemia. People with autoimmune atrophic gastritis do not produce enough intrinsic factor. Intrinsic factor is a protein made in the stomach and helps the intestines absorb vitamin B12. The body needs vitamin B12 to make red blood cells and nerve cells. Poor absorption of vitamin B12 may lead to a type of anemia called pernicious anemia. Read more about pernicious anemia at www.nhlbi.nih.gov.  - growths in the stomach lining. Chronic gastritis increases the chance of developing benign, or noncancerous, and malignant, or cancerous, growths in the stomach lining. Chronic H. pylori gastritis increases the chance of developing a type of cancer called gastric mucosa-associated lymphoid tissue (MALT) lymphoma. Read more about MALT lymphoma and gastric cancer at www.cancer.gov.
                
In most cases, acute gastritis does not lead to complications. In rare cases, acute stress gastritis can cause severe bleeding that can be life threatening.
What are the treatments for Gastritis ? 
 Health care providers treat gastritis with medications to
                
- reduce the amount of acid in the stomach  - treat the underlying cause
                
Reduce the Amount of Acid in the Stomach
                
The stomach lining of a person with gastritis may have less protection from acidic digestive juice. Reducing acid can promote healing of the stomach lining. Medications that reduce acid include
                
- antacids, such as Alka-Seltzer, Maalox, Mylanta, Rolaids, and Riopan. Many brands use different combinations of three basic saltsmagnesium, aluminum, and calciumalong with hydroxide or bicarbonate ions to neutralize stomach acid. Antacids, however, can have side effects. Magnesium salt can lead to diarrhea, and aluminum salt can cause constipation. Magnesium and aluminum salts are often combined in a single product to balance these effects. Calcium carbonate antacids, such as Tums, Titralac, and Alka-2, can cause constipation.  - H2 blockers, such as cimetidine (Tagamet HB), famotidine (Pepcid AC), nizatidine (Axid AR), and ranitidine (Zantac 75). H2 blockers decrease acid production. They are available in both over-the-counter and prescription strengths.  - proton pump inhibitors (PPIs) include omeprazole (Prilosec, Zegerid), lansoprazole (Prevacid), dexlansoprazole (Dexilant), pantoprazole (Protonix), rabeprazole (AcipHex), and esomeprazole (Nexium). PPIs decrease acid production more effectively than H2 blockers. All of these medications are available by prescription. Omeprazole and lansoprazole are also available in over-the-counter strength.
                
Treat the Underlying Cause
                
Depending on the cause of gastritis, a health care provider may recommend additional treatments.
                
- Treating H. pylori infection with antibiotics is important, even if a person does not have symptoms from the infection. Curing the infection often cures the gastritis and decreases the chance of developing complications, such as peptic ulcer disease, MALT lymphoma, and gastric cancer.  - Avoiding the cause of reactive gastritis can provide some people with a cure. For example, if prolonged NSAID use is the cause of the gastritis, a health care provider may advise the patient to stop taking the NSAIDs, reduce the dose, or change pain medications.  - Health care providers may prescribe medications to prevent or treat stress gastritis in a patient who is critically ill or injured. Medications to protect the stomach lining include sucralfate (Carafate), H2 blockers, and PPIs. Treating the underlying illness or injury most often cures stress gastritis.  - Health care providers may treat people with pernicious anemia due to autoimmune atrophic gastritis with vitamin B12 injections.
How to prevent Gastritis ? 
 People may be able to reduce their chances of getting gastritis by preventing H. pylori infection. No one knows for sure how H. pylori infection spreads, so prevention is difficult. To help prevent infection, health care providers advise people to
                
- wash their hands with soap and water after using the bathroom and before eating  - eat food that has been washed well and cooked properly  - drink water from a clean, safe source
What to do for Gastritis ? 
 Researchers have not found that eating, diet, and nutrition play a major role in causing or preventing gastritis.
What to do for Gastritis ? 
 - Gastritis is a condition in which the stomach liningknown as the mucosais inflamed, or swollen.  - Common causes of gastritis include Helicobacter pylori (H. pylori) infection, damage to the stomach lining, and an autoimmune response.  - Some people who have gastritis have pain or discomfort in the upper part of the abdomen. However, many people with gastritis do not have any signs and symptoms.  - Erosive gastritis may cause ulcers or erosions in the stomach lining that can bleed. A person with any signs or symptoms of bleeding in the stomach should call or see a health care provider right away.  - A health care provider diagnoses gastritis based on a medical history, a physical exam, upper GI endoscopy, and other tests.  - Health care providers treat gastritis with medications to reduce the amount of acid in the stomach and treat the underlying cause.
What is (are) Multiple Endocrine Neoplasia Type 1 ? 
 MEN1 is an inherited disorder that causes tumors in the endocrine glands and the duodenum, the first part of the small intestine. MEN1 is sometimes called multiple endocrine adenomatosis or Wermer's syndrome, after one of the first doctors to recognize it. MEN1 is rare, occurring in about one in 30,000 people.1 The disorder affects both sexes equally and shows no geographical, racial, or ethnic preferences.
                
Endocrine glands release hormones into the bloodstream. Hormones are powerful chemicals that travel through the blood, controlling and instructing the functions of various organs. Normally, the hormones released by endocrine glands are carefully balanced to meet the body's needs.
                
In people with MEN1, multiple endocrine glands form tumors and become hormonally overactive, often at the same time. The overactive glands may include the parathyroids, pancreas, or pituitary. Most people who develop overactivity of only one endocrine gland do not have MEN1.
What to do for Multiple Endocrine Neoplasia Type 1 ? 
 - Multiple endocrine neoplasia type 1 (MEN1) is an inherited disorder that causes hormone-secreting tumors in the duodenum and the endocrine glands-most often the parathyroid, pancreas, and pituitary.  - Overactive parathyroid glands can lead to tiredness, weakness, muscle or bone pain, constipation, indigestion, kidney stones, or thinning of bones.  - Pancreatic and duodenal endocrine tumors called gastrinomas can cause dangerous stomach or intestinal ulcers.  - Pituitary tumors called prolactinomas can cause excessive production of breast milk or interfere with fertility in women or with sex drive and fertility in men.  - Although many tumors associated with MEN1 are benign, about half of people with MEN1 will eventually develop a cancerous tumor.  - MEN1 carriers can be detected through gene testing or other laboratory tests.  - MEN1 cannot be cured, but regular testing can detect the problems caused by MEN1 tumors many years before serious complications develop. Careful monitoring enables doctors to adjust an individual's treatment as needed.
What is (are) Autoimmune Hepatitis ? 
 Autoimmune hepatitis is a chronicor long lastingdisease in which the body's immune system attacks the normal components, or cells, of the liver and causes inflammation and liver damage. The immune system normally protects people from infection by identifying and destroying bacteria, viruses, and other potentially harmful foreign substances.
                
Autoimmune hepatitis is a serious condition that may worsen over time if not treated. Autoimmune hepatitis can lead to cirrhosis and liver failure. Cirrhosis occurs when scar tissue replaces healthy liver tissue and blocks the normal flow of blood through the liver. Liver failure occurs when the liver stops working properly.