Druvith/transformed_medDataset huggingface dataset:
What is (are) Irritable Bowel Syndrome in Children ? 
 The GI tract is a series of hollow organs joined in a long, twisting tube from the mouth to the anus. The movement of muscles in the GI tract, along with the release of hormones and enzymes, allows for the digestion of food. Organs that make up the GI tract are the mouth, esophagus, stomach, small intestine, large intestinewhich includes the appendix, cecum, colon, and rectumand anus. The intestines are sometimes called the bowel. The last part of the GI tractcalled the lower GI tractconsists of the large intestine and anus.
                
The large intestine absorbs water and any remaining nutrients from partially digested food passed from the small intestine. The large intestine then changes waste from liquid to a solid matter called stool. Stool passes from the colon to the rectum. The rectum is located between the last part of the coloncalled the sigmoid colonand the anus. The rectum stores stool prior to a bowel movement. During a bowel movement, stool moves from the rectum to the anus, the opening through which stool leaves the body.
How many people are affected by Irritable Bowel Syndrome in Children ? 
 Limited information is available about the number of children with IBS. Older studies have reported prevalence rates for recurrent abdominal pain in children of 10 to 20 percent.1 However, these studies did not differentiate IBS from functional abdominal pain, indigestion, and abdominal migraine. One study of children in North America found that 14 percent of high school students and 6 percent of middle school students have IBS. The study also found that IBS affects boys and girls equally.2
What are the symptoms of Irritable Bowel Syndrome in Children ? 
 The symptoms of IBS include abdominal pain or discomfort and changes in bowel habits. To meet the definition of IBS, the pain or discomfort should be associated with two of the following three symptoms:
                
- start with bowel movements that occur more or less often than usual  - start with stool that appears looser and more watery or harder and more lumpy than usual  - improve with a bowel movement
                
Other symptoms of IBS may include
                
- diarrheahaving loose, watery stools three or more times a day and feeling urgency to have a bowel movement  - constipationhaving hard, dry stools; two or fewer bowel movements in a week; or straining to have a bowel movement  - feeling that a bowel movement is incomplete  - passing mucus, a clear liquid made by the intestines that coats and protects tissues in the GI tract  - abdominal bloating
                
Symptoms may often occur after eating a meal. To meet the definition of IBS, symptoms must occur at least once per week for at least 2 months.
What causes Irritable Bowel Syndrome in Children ? 
 The causes of IBS are not well understood. Researchers believe a combination of physical and mental health problems can lead to IBS. The possible causes of IBS in children include the following:
                
- Brain-gut signal problems. Signals between the brain and nerves of the small and large intestines, also called the gut, control how the intestines work. Problems with brain-gut signals may cause IBS symptoms, such as changes in bowel habits and pain or discomfort.  - GI motor problems. Normal motility, or movement, may not be present in the colon of a child who has IBS. Slow motility can lead to constipation and fast motility can lead to diarrhea. Spasms, or sudden strong muscle contractions that come and go, can cause abdominal pain. Some children with IBS also experience hyperreactivity, which is an excessive increase in contractions of the bowel in response to stress or eating.  - Hypersensitivity. Children with IBS have greater sensitivity to abdominal pain than children without IBS. Affected children have been found to have different rectal tone and rectal motor response after eating a meal.  - Mental health problems. IBS has been linked to mental health, or psychological, problems such as anxiety and depression in children.  - Bacterial gastroenteritis. Some children who have bacterial gastroenteritisan infection or irritation of the stomach and intestines caused by bacteriadevelop IBS. Research has shown a connection between gastroenteritis and IBS in adults but not in children. But researchers believe postinfectious IBS does occur in children. Researchers do not know why gastroenteritis leads to IBS in some people and not others.  - Small intestinal bacterial overgrowth (SIBO). Normally, few bacteria live in the small intestine. SIBO is an increase in the number of bacteria or a change in the type of bacteria in the small intestine. These bacteria can produce excess gas and may also cause diarrhea and weight loss. Some researchers believe that SIBO may lead to IBS, and some studies have shown antibiotics to be effective in treating IBS. However, the studies were weak and more research is needed to show a link between SIBO and IBS.  - Genetics. Whether IBS has a genetic cause, meaning it runs in families, is unclear. Studies have shown that IBS is more common in people with family members who have a history of GI problems. However, the cause could be environmental or the result of heightened awareness of GI symptoms.
What are the treatments for Irritable Bowel Syndrome in Children ? 
 Though there is no cure for IBS, the symptoms can be treated with a combination of the following:
                
- changes in eating, diet, and nutrition  - medications  - probiotics  - therapies for mental health problems
What to do for Irritable Bowel Syndrome in Children ? 
 - Irritable bowel syndrome (IBS) is a functional gastrointestinal (GI) disorder, meaning it is a problem caused by changes in how the GI tract works. Children with a functional GI disorder have frequent symptoms, but the GI tract does not become damaged.  - IBS is not a disease; it is a group of symptoms that occur together.  - The most common symptoms of IBS are abdominal pain or discomfort, often reported as cramping, along with diarrhea, constipation, or both.  - The causes of IBS are not well understood. The possible causes of IBS in children include brain-gut signal problems, GI motor problems, hypersensitivity, mental health problems, bacterial gastroenteritis, small intestinal bacterial overgrowth, and genetics.  - To diagnose IBS, a health care provider will conduct a physical exam and take a complete medical history. The medical history will include questions about the childs symptoms, family members with GI disorders, recent infections, medications, and stressful events related to the onset of symptoms. IBS is diagnosed when the physical exam does not show any cause for the childs symptoms and the child meets all of the following criteria:      - has had symptoms at least once per week for at least 2 months    - is growing as expected    - is not showing any signs that suggest another cause for the symptoms    - Though there is no cure for IBS, the symptoms can be treated with a combination of the following:      - changes in eating, diet, and nutrition    - medications    - probiotics    - therapies for mental health problems
What is (are) What I need to know about Gestational Diabetes ? 
 Gestational* diabetes is a type of diabetes that develops only during pregnancy. Diabetes means your blood glucose, also called blood sugar, is too high. Your body uses glucose for energy. Too much glucose in your blood is not good for you or your baby.
                
Gestational diabetes is usually diagnosed during late pregnancy. If you are diagnosed with diabetes earlier in your pregnancy, you may have had diabetes before you became pregnant.
                
Treating gestational diabetes can help both you and your baby stay healthy. You can protect your baby and yourself by taking action right away to control your blood glucose levels.
                
If you have gestational diabetes, a health care team will likely be part of your care. In addition to your obstetrician-gynecologist, or OB/GYNthe doctor who will deliver your babyyour team might include a doctor who treats diabetes, a diabetes educator, and a dietitian to help you plan meals.
                
For Women with Type 1 or Type 2 Diabetes   If you already have type 1 or type 2 diabetes and are thinking about having a baby, talk with your doctor before you get pregnant. Untreated or poorly controlled diabetes can cause serious problems for your baby. More information is provided in the NIDDK health topic, What I need to know about Preparing for Pregnancy if I Have Diabetes or call 18008608747 and request a copy.
                
*See the Pronunciation Guide for tips on how to say the words in bold type.
What causes What I need to know about Gestational Diabetes ? 
 Gestational diabetes happens when your body can't make enough insulin during pregnancy. Insulin is a hormone made in your pancreas, an organ located behind your stomach. Insulin helps your body use glucose for energy and helps control your blood glucose levels.
                
During pregnancy, your body makes more hormones and goes through other changes, such as weight gain. These changes cause your body's cells to use insulin less effectively, a condition called insulin resistance. Insulin resistance increases your body's need for insulin. If your pancreas can't make enough insulin, you will have gestational diabetes.
                
All pregnant women have some insulin resistance during late pregnancy. However, some women have insulin resistance even before they get pregnant, usually because they are overweight. These women start pregnancy with an increased need for insulin and are more likely to have gestational diabetes.
                

                
What are my chances of getting gestational diabetes?   Your chances of getting gestational diabetes are higher if you   - are overweight   - have had gestational diabetes before   - have given birth to a baby weighing more than 9 pounds   - have a parent, brother, or sister with type 2 diabetes   - have prediabetes, meaning your blood glucose levels are higher than normal yet not high enough for a diagnosis of diabetes   - are African American, American Indian, Asian American, Hispanic/Latina, or Pacific Islander American   - have a hormonal disorder called polycystic ovary syndrome, also known as PCOS
What is (are) What I need to know about Gestational Diabetes ? 
 Your chances of getting gestational diabetes are higher if you
                
- are overweight  - have had gestational diabetes before  - have given birth to a baby weighing more than 9 pounds  - have a parent, brother, or sister with type 2 diabetes  - have prediabetes, meaning your blood glucose levels are higher than normal yet not high enough for a diagnosis of diabetes  - are African American, American Indian, Asian American, Hispanic/Latina, or Pacific Islander American  - have a hormonal disorder called polycystic ovary syndrome, also known as PCOS
How to diagnose What I need to know about Gestational Diabetes ? 
 Doctors use blood tests to diagnose gestational diabetes. All diabetes blood tests involve drawing blood at a doctor's office or a commercial facility. Blood samples are sent to a lab for analysis.
                

                
Screening Glucose Challenge Test
                
For this test, you will drink a sugary beverage and have your blood glucose level checked an hour later. This test can be done at any time of the day. If the results are above normal, you may need to have an oral glucose tolerance test.
                
Oral Glucose Tolerance Test
                
You will need to fast for at least 8 hours before the test. Fasting means having nothing to eat or drink except water. Your doctor will give you other instructions to follow before the test.
                
Your fasting blood glucose level will be checked before the test begins. Then you will drink a sugary beverage. Your blood glucose levels will be checked 1 hour, 2 hours, and possibly 3 hours later. Your doctor will use your test results to find out whether you have gestational diabetes.
How to diagnose What I need to know about Gestational Diabetes ? 
 If you have gestational diabetes, your doctor may recommend that you have some extra tests to check your baby's health, such as
                
- ultrasound exams, which use sound waves to make images that show your baby's growth and whether your baby is larger than normal  - a nonstress test, which uses a monitor placed on your abdomen to check whether your baby's heart rate increases as it should when your baby is active  - kick counts to check the time between your baby's movements
What are the treatments for What I need to know about Gestational Diabetes ? 
 Treating gestational diabetes means taking steps to keep your blood glucose levels in a target range. Targets are numbers you aim for. Your doctor will help you set your targets. You will learn how to control your blood glucose using
                
- healthy eating  - physical activity  - insulin shots, if needed
What to do for What I need to know about Gestational Diabetes ? 
 Your health care team will help you make a healthy eating plan with food choices that are good for both you and your baby. These choices are good for you to follow throughout pregnancy and after, as you raise your family.
                
Using a healthy eating plan will help your blood glucose stay in your target range. The plan will help you know which foods to eat, how much to eat, and when to eat. Food choices, amounts, and timing are all important in keeping your blood glucose levels in your target range.
                
More information is provided in the NIDDK health topic, What I need to know about Eating and Diabetes.
                

                
Physical Activity
                
Physical activity can help you reach your blood glucose targets. Talk with your doctor about the type of activity that is best for you. If you are already active, tell your doctor what you do. Being physically active will also help lower your chances of having type 2 diabetesand its problemsin the future. Now is the time to develop good habits for you and your baby.
                
For more information about physical activity and pregnancy, visit www.womenshealth.gov/pregnancy.
                
Insulin Shots
                
If you have trouble meeting your blood glucose targets, you may need to take a medicine called insulin, along with following a healthy meal plan and being physically active. Your health care team will show you how to give yourself insulin shots. Insulin will not harm your baby.
How to diagnose What I need to know about Gestational Diabetes ? 
 Your health care team may teach you how to test for chemicals called ketones in your morning urine or in your blood. High levels of ketones are a sign that your body is using your body fat for energy instead of the food you eat. Using fat for energy is not recommended during pregnancy. Ketones may be harmful for your baby.
                
If your ketone levels are high, your doctor may suggest that you change the type or amount of food you eat. Or you may need to change your meal or snack times.
How to prevent What I need to know about Gestational Diabetes ? 
 You can do a lot to prevent or delay type 2 diabetes by making these lifestyle changes:
                
- Reach and stay at a healthy weight. Try to reach your prepregnancy weight 6 to 12 months after your baby is born. Then, if you still weigh too much, work to lose at least 5 to 7 percent of your body weight and keep it off. For example, if you weigh 200 pounds, losing 10 to 14 pounds can greatly reduce your chance of getting diabetes.  - Be physically active for at least 30 minutes most days of the week.  - Follow a healthy eating plan. Eat more grains, fruits, and vegetables. Cut down on fat and calories. Your health care team can help you design a meal plan.  - Ask your doctor if you should take the diabetes medicine metformin. Metformin can lower your chances of having type 2 diabetes, especially if you are younger and heavier and have prediabetes or if you have had gestational diabetes.
                
These changes can help you enjoy a longer, healthier life. Your health care team can give you information and support to help you make these changes.
                
By delaying or preventing type 2 diabetes, you will also lower your chances of having heart and blood vessel disease and other problems as you get older.
                
Talk with your doctor if you are thinking about having another baby. For the safety of your baby, your blood glucose needs to be at healthy levels before you get pregnant again. Your doctor can help ensure you are ready for your next child.
What to do for What I need to know about Gestational Diabetes ? 
 - Gestational diabetes is a type of diabetes that develops only during pregnancy. Diabetes means your blood glucose, also called blood sugar, is too high.  - Gestational diabetes happens when your body can't make enough insulin during pregnancy. Insulin is a hormone made in your pancreas, an organ located behind your stomach. Insulin helps your body use glucose for energy and helps control your blood glucose levels.  - You will probably be tested for gestational diabetes between weeks 24 and 28 of your pregnancy. If you have a higher chance of getting gestational diabetes, your doctor may test you for diabetes during your first visit after you become pregnant.  - If you have high blood glucose levels because your gestational diabetes is not under control, your baby will also have high blood glucose.  - Untreated or uncontrolled gestational diabetes can cause problems for your baby.  - Treating gestational diabetes means taking steps to keep your blood glucose levels in a target range.  - Even if your blood glucose levels return to normal after your pregnancy, your chances of getting diabetesusually type 2 diabeteslater in life are high. Therefore, you should be tested at least every 3 years for diabetes or prediabetes.  - You can give your baby a healthy start by breastfeeding.  - You can help your child be healthy by showing your child how to make healthy lifestyle choices, including being physically active, limiting screen time in front of the TV or video games, eating a healthy diet, and staying at a healthy weight.
What is (are) Human Growth Hormone and Creutzfeldt-Jakob Disease Resource List ? 
 MAGIC (Major Aspects of Growth in Children) Foundation is a national, nonprofit organization that provides support and education about growth disorders in children and growth hormone deficiency in adults. Staff will help connect people who have similar interests or concerns.
                
The Human Growth Foundation (HGF) is a nonprofit organization concerned with childrens growth disorders and adult growth hormone deficiency. The HGF offers a brochure about adult growth hormone deficiency. The foundation also sponsors adult and pediatric Internet discussion forums to support the exchange of information about growth hormone deficiency and growth hormone replacement therapy. To subscribe, follow the instructions at www.hgfound.org.
                
The Creutzfeldt-Jakob Disease (CJD) Foundation, Inc. was created in 1993 by two families who lost relatives to CJD and the neurologist who treated the patients. This nonprofit corporation seeks to promote awareness of CJD through research and education and to reach out to people who have lost loved ones to this illness.
What is (are) Human Growth Hormone and Creutzfeldt-Jakob Disease Resource List ? 
 Health Alert: Adrenal Crisis Causes Death in Some People Who Were Treated with Human Growth Hormone
                
National Hormone and Pituitary Program (NHPP): Information for People Treated with Pituitary Human Growth Hormone (Summary)
                
National Hormone and Pituitary Program (NHPP): Information for People Treated with Pituitary Human Growth Hormone (Comprehensive Report)
                
Creutzfeldt-Jakob Disease. Fact sheet of the National Institute of Neurological Disorders and Stroke, National Institutes of Health (NIH)
                
NIH and Italian Scientists Develop Nasal Test for Human Prion Disease
                
What is a prion?from Scientific American: Ask the Experts
What is (are) Liver (Hepatocellular) Cancer ? 
 Key Points
                    - Liver cancer is a disease in which malignant (cancer) cells form in the tissues of the liver.    - Liver cancer is less common in the United States than in other parts of the world.    - Having hepatitis or cirrhosis can increase the risk of developing liver cancer.
                
                
                    Liver cancer is a disease in which malignant (cancer) cells form in the tissues of the liver.
                    The liver is one of the largest organs in the body. It has four lobes and fills the upper right side of the abdomen inside the rib cage. Three of the many important functions of the liver are:         - To filter harmful substances from the blood so they can be passed from the body in stools and urine.    - To make bile to help digest fats from food.    - To store glycogen (sugar), which the body uses for energy.         See the following PDQ summaries for more information about liver (hepatocellular) cancer:         -  Liver (Hepatocellular) Cancer Prevention     -  Adult Primary Liver Cancer Treatment     -  Childhood Liver Cancer Treatment
                
                
                    Liver cancer is less common in the United States than in other parts of the world.
                    Liver cancer is uncommon in the United States, but is the fourth most common cancer in the world. In the United States, men, especially Chinese American men, have a greater risk of developing liver cancer.
Who is at risk for Liver (Hepatocellular) Cancer? ? 
 Having hepatitis or cirrhosis can increase the risk of developing liver cancer. Anything that increases the chance of getting a disease is called a risk factor. Having a risk factor does not mean that you will get cancer; not having risk factors doesn't mean that you will not get cancer. People who think they may be at risk should discuss this with their doctor. Risk factors for liver cancer include:         - Having hepatitis B or hepatitis C; having both hepatitis B and hepatitis C increases the risk even more.    - Having cirrhosis, which can be caused by:                -  hepatitis (especially hepatitis C); or      - drinking large amounts of alcohol for many years or being an alcoholic.             - Eating foods tainted with aflatoxin (poison from a fungus that can grow on foods, such as grains and nuts, that have not been stored properly).