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A 25-year-old immunocompetent lady presented with pain and redness in the left eye of 1-month duration .
{ "id": "C0041834", "pos": [ 59, 66 ], "name": "redness" }
{ "id": "C0229090", "pos": [ 74, 82 ], "name": "left eye" }
0NA
The maximum extraction yield of each of the silymarin compounds and taxifolin did not increase with temperature , most likely because significant compound degradation occurred .
{ "id": "C0185115", "pos": [ 12, 22 ], "name": "extraction" }
{ "id": "C0005903", "pos": [ 100, 111 ], "name": "temperature" }
0NA
The radiographs were taken while the patients were with the knee in 90 degrees flexion .
{ "id": "C0022742", "pos": [ 60, 64 ], "name": "knee" }
{ "id": "C1306645", "pos": [ 4, 15 ], "name": "radiographs" }
0NA
Evolution of body weight , systolic blood pressure ( BP ) , plasma calcium and magnesium was monitored from 4 to 23 weeks of age .
{ "id": "C0024467", "pos": [ 79, 88 ], "name": "magnesium" }
{ "id": "C0006675", "pos": [ 67, 74 ], "name": "calcium" }
0NA
We conclude that prostaglandin E1 but not hydralazine is effective in decreasing Ppc in this experimental model of pulmonary hypertension .
{ "id": "C0020223", "pos": [ 42, 53 ], "name": "hydralazine" }
{ "id": "C0002335", "pos": [ 17, 33 ], "name": "prostaglandin E1" }
0NA
Excessive production of triglyceride-rich VLDL , which can result from dietary overindulgence , underlies metabolic syndrome -- a combination of disorders including high blood pressure , obesity , high triglyceride , and insulin resistance -- and places individuals at increased risk of developing cardiovascular disease and type 2 diabetes .
{ "id": "C0012634", "pos": [ 145, 154 ], "name": "disorders" }
{ "id": "C0011860", "pos": [ 325, 340 ], "name": "type 2 diabetes" }
0NA
We studied 37 patients with amaurosis fugax and angiographic evidence of carotid atherosclerosis ipsilateral to the symptomatic eye .
{ "id": "C0015392", "pos": [ 128, 131 ], "name": "eye" }
{ "id": "C0149793", "pos": [ 28, 43 ], "name": "amaurosis fugax" }
0NA
The average staining intensity was highest in the upper third of the esophagus and then declined in a statistically significant manner in the middle and lower thirds .
{ "id": "C0014876", "pos": [ 69, 78 ], "name": "esophagus" }
{ "id": "C0227187", "pos": [ 50, 61 ], "name": "upper third" }
0NA
Focused echocardiography can detect various cardiac pathologies , such as pericardial effusion , left ventricular dysfunction , right heart strain , relevant heart valve defects and dissection of the ascending aorta .
{ "id": "C0018826", "pos": [ 158, 169 ], "name": "heart valve" }
{ "id": "C0031039", "pos": [ 74, 94 ], "name": "pericardial effusion" }
0NA
B-mode ultrasound imaging of the diaphragm is a highly sensitive and specific tool for diagnosis of neuromuscular diaphragm dysfunction .
{ "id": "C0011980", "pos": [ 33, 42 ], "name": "diaphragm" }
{ "id": "C0020517", "pos": [ 55, 64 ], "name": "sensitive" }
0NA
Complement component C3 , however , was observed by immunofluorescence in the cranioventral , virus-infected portion of the lungs of 19 of 25 calves .
{ "id": "C0024109", "pos": [ 124, 129 ], "name": "lungs" }
{ "id": "C0016318", "pos": [ 52, 70 ], "name": "immunofluorescence" }
0NA
In particular , the possibility of using mechanical retractors to lift the abdominal wall as an alternative to pneumoperitoneum now enables surgeons to operate simultaneously using a transvaginal and laparoscopic approach .
{ "id": "C0836916", "pos": [ 75, 89 ], "name": "abdominal wall" }
{ "id": "C0032320", "pos": [ 111, 127 ], "name": "pneumoperitoneum" }
0NA
Subsequently , the rate of HCV infection in the Saudi Arabian population was stabilized through effective screening of blood and infection control measures .
{ "id": "C0009450", "pos": [ 31, 40 ], "name": "infection" }
{ "id": "C0085557", "pos": [ 129, 146 ], "name": "infection control" }
12focus_of
The diagnosis of subclinical suppuration in operative wounds after removal of drainage tubes can be established after ultrasonic investigation of the wound .
{ "id": "C0015252", "pos": [ 67, 74 ], "name": "removal" }
{ "id": "C0043250", "pos": [ 150, 155 ], "name": "wound" }
0NA
A significant complication of the TA approach via thyroid cartilage was a hematoma in one patient which partially obstructed the laryngeal lumen .
{ "id": "C0023078", "pos": [ 129, 138 ], "name": "laryngeal" }
{ "id": "C0040126", "pos": [ 50, 67 ], "name": "thyroid cartilage" }
0NA
Treatment was 16 intraparenchymal deposits ( four in the cerebellum ) of a recombinant adenoassociated viral vector serotype 2/5 ( rAAV2/5 ) encoding human α-N-acetylglucosaminidase ( NAGLU ) plus immunosuppressive therapy .
{ "id": "C0007765", "pos": [ 57, 67 ], "name": "cerebellum" }
{ "id": "C0021079", "pos": [ 197, 222 ], "name": "immunosuppressive therapy" }
0NA
Analysis of all outcomes for warfarin versus aspirin was based on 3663 patients from four RCTs .
{ "id": "C0004057", "pos": [ 45, 52 ], "name": "aspirin" }
{ "id": "C0043031", "pos": [ 29, 37 ], "name": "warfarin" }
0NA
The infraoccluded primary teeth remain in a fixed position , while the teeth adjacent to them continue to erupt , moving occlusally .
{ "id": "C0040426", "pos": [ 71, 76 ], "name": "teeth" }
{ "id": "C3266841", "pos": [ 18, 31 ], "name": "primary teeth" }
0NA
Principles of wound closure and chest wall stabilization , where indicated , are discussed .
{ "id": "C0205076", "pos": [ 32, 42 ], "name": "chest wall" }
{ "id": "C1293130", "pos": [ 43, 56 ], "name": "stabilization" }
0NA
Administration of N , N-di-n-propyldopamine ( DPDA ) ( 1 - 100 micrograms/kg i.v . ) and LY171555 ( 1 - 100 micrograms/kg i.v . ) produced dose-related arterial hypotension accompanied by bradycardia in anesthetized rhesus monkey .
{ "id": "C0428977", "pos": [ 188, 199 ], "name": "bradycardia" }
{ "id": "C0003842", "pos": [ 152, 160 ], "name": "arterial" }
0NA
To evaluate the epithelial thickness , number of vessels , amount of collagen and muscular fibers of the bladder and urethra of castrated adult female rats during the time between castration and the beginning of the administration of synthetic conjugated estrogen .
{ "id": "C0005682", "pos": [ 105, 112 ], "name": "bladder" }
{ "id": "C0005847", "pos": [ 49, 56 ], "name": "vessels" }
0NA
Several studies have provided evidence for the validity of monitoring dynamic mechanics of the respiratory system to estimate the balance between beneficial ( i.e. reduction of alveolar derecruitment ) and harmful ( i.e. lung hyperinflation ) effects , consequent to positive end-expiratory pressure increase .
{ "id": "C0035237", "pos": [ 95, 113 ], "name": "respiratory system" }
{ "id": "C0150369", "pos": [ 59, 69 ], "name": "monitoring" }
0NA
Preoperative evaluation noted the existence of HIT with heparin exposure 2 months prior .
{ "id": "C0019134", "pos": [ 56, 63 ], "name": "heparin" }
{ "id": "C0272285", "pos": [ 47, 50 ], "name": "HIT" }
4causative_agent_of
After perfusion for two hours with 2 mM auranofin the jejunal mucosa showed severe injury by light and scanning electronmicroscopy while myochrysine had no apparent effect .
{ "id": "C0205082", "pos": [ 76, 82 ], "name": "severe" }
{ "id": "C0004320", "pos": [ 40, 49 ], "name": "auranofin" }
0NA
In conclusion , emotional and cognitive deficits are observed in EAE prior to demyelination and are associated with elevated IL-1β and TNF-α in the hypothalamus and changes in the hypothalamic-pituitary-adrenal axis .
{ "id": "C0009241", "pos": [ 30, 48 ], "name": "cognitive deficits" }
{ "id": "C0013987", "pos": [ 16, 25 ], "name": "emotional" }
0NA
The effects of temperature , oil/alcohol molar ratio and by-product glycerol were studied during Lipozyme TL IM-catalysed continuous batch operation when short-chain alcohols were used as the acyl acceptor .
{ "id": "C0543467", "pos": [ 139, 148 ], "name": "operation" }
{ "id": "C0017861", "pos": [ 68, 76 ], "name": "glycerol" }
0NA
Analysis of the HEXA gene showed that they were compound heterozygotes for the functionally silent 4-bp insertion in exon 11 , typical of the infantile form of the disease and for a novel mutation , T538 - ->C , resulting in the missense Tyr180 - ->His .
{ "id": "C0021107", "pos": [ 104, 113 ], "name": "insertion" }
{ "id": "C0012634", "pos": [ 164, 171 ], "name": "disease" }
0NA
Elevated BMI or diabetes may negatively impact both overall survival and local control in patients with brain metastases from breast cancer , highlighting the importance of the translational development of therapeutic metabolic interventions .
{ "id": "C0006142", "pos": [ 126, 139 ], "name": "breast cancer" }
{ "id": "C0220650", "pos": [ 104, 120 ], "name": "brain metastases" }
0NA
Future research should involve a larger , more inclusive autism spectrum disorder sample , broaden approaches to exploring relationships between social perception and adaptive outcomes , and relate findings to brain mechanisms underlying emotion perception .
{ "id": "C0006104", "pos": [ 210, 215 ], "name": "brain" }
{ "id": "C0524528", "pos": [ 57, 81 ], "name": "autism spectrum disorder" }
0NA
We sought to quantify potential redundancy in our brain MRI protocols .
{ "id": "C0006104", "pos": [ 50, 55 ], "name": "brain" }
{ "id": "C0024485", "pos": [ 56, 59 ], "name": "MRI" }
0NA
Therefore Cerebellopontine Angle ( CPA ) tumors affect patients ' balance .
{ "id": "C0027651", "pos": [ 41, 47 ], "name": "tumors" }
{ "id": "C0007764", "pos": [ 10, 32 ], "name": "Cerebellopontine Angle" }
0NA
His first complaints were forgetfulness , mild changes in his behaviour , confusion and difficulty in speech .
{ "id": "C1299586", "pos": [ 88, 98 ], "name": "difficulty" }
{ "id": "C0009676", "pos": [ 74, 83 ], "name": "confusion" }
0NA
On urgent gastroscopy , large blood clots obscured the site of hemorrhage .
{ "id": "C0019080", "pos": [ 63, 73 ], "name": "hemorrhage" }
{ "id": "C0017195", "pos": [ 10, 21 ], "name": "gastroscopy" }
0NA
The expressions of CD56 + , CD34 + , lymphoid antigen in adult AML patients , who have lower CR rate , often signify poor prognosis .
{ "id": "C0185117", "pos": [ 4, 15 ], "name": "expressions" }
{ "id": "C0023467", "pos": [ 63, 66 ], "name": "AML" }
0NA
In this study , we hypothesized that the lumbar spine with implanted total spinal segment replacement ( TSSR ) would exhibit decreased dynamic stiffness and more rapid energy absorption compared to native functional spinal units under simulated physiologic motion when tested with the pendulum system .
{ "id": "C0021102", "pos": [ 59, 68 ], "name": "implanted" }
{ "id": "C0024091", "pos": [ 41, 53 ], "name": "lumbar spine" }
0NA
A combined three-dimensional and axisymmetric finite element analysis was made of the effect upon the peak interfacial shear stress of providing an axially loaded mandibular dental implant with retention elements all the way up to the crest of the implant as opposed to a smooth neck .
{ "id": "C0021102", "pos": [ 248, 255 ], "name": "implant" }
{ "id": "C0024687", "pos": [ 163, 173 ], "name": "mandibular" }
0NA
The examination involved clinical as well as functional tests ( the unit " Cardiocid"-aided ECG , EchoCG on the " Combison-420 - 5 " ) , with the renal function being evaluated as recommended by Ota Shiuk .
{ "id": "C0031809", "pos": [ 4, 15 ], "name": "examination" }
{ "id": "C0232804", "pos": [ 146, 160 ], "name": "renal function" }
0NA
Thus , the increased oxidative metabolism associated with activation of HSP72 has potential clinical implications not only for type 2 diabetes but also for other disorders where mitochondrial function is compromised .
{ "id": "C0012634", "pos": [ 162, 171 ], "name": "disorders" }
{ "id": "C0011860", "pos": [ 127, 142 ], "name": "type 2 diabetes" }
0NA
Biopsy findings of severe villous atrophy permitted diagnosis of celiac disease in 7.7 % ( 5/65 children ) .
{ "id": "C0005558", "pos": [ 0, 6 ], "name": "Biopsy" }
{ "id": "C0007570", "pos": [ 65, 79 ], "name": "celiac disease" }
0NA
The frequency of pulpal healing ( versus pulp necrosis ) , appeared to be closely related to stage of root development at time of transplantation .
{ "id": "C0040732", "pos": [ 130, 145 ], "name": "transplantation" }
{ "id": "C0011407", "pos": [ 41, 54 ], "name": "pulp necrosis" }
0NA
It seems that the edge-to-edge technique for mitral commissural prolapse due to degenerative disease is a technically simple , highly effective procedure .
{ "id": "C0184661", "pos": [ 144, 153 ], "name": "procedure" }
{ "id": "C1285162", "pos": [ 80, 100 ], "name": "degenerative disease" }
0NA
Our data provide further insight into OTA bioactivation that may account for its in vivo mutagenicity in male rat kidney .
{ "id": "C0022646", "pos": [ 114, 120 ], "name": "kidney" }
{ "id": "C0086582", "pos": [ 105, 109 ], "name": "male" }
0NA
Frozen tissue samples ( 1 gm ) were homogenized and analyzed for lipid peroxides by malondialdehyde and hydrogen peroxide equivalents and for thromboxane and prostacyclin by radioimmunoassay of their stable metabolites , thromboxane B2 and 6-keto prostaglandin F1 alpha .
{ "id": "C0870883", "pos": [ 207, 218 ], "name": "metabolites" }
{ "id": "C0033567", "pos": [ 158, 170 ], "name": "prostacyclin" }
0NA
The patient ( female , age 71 ) underwent a resection of the small bowl and mesentery of the recurrent MFH with negative resection margins .
{ "id": "C0015252", "pos": [ 44, 53 ], "name": "resection" }
{ "id": "C0334463", "pos": [ 103, 106 ], "name": "MFH" }
0NA
We believe that the results reveal interesting physical insights in the field of network control and allow extensive applications of matrix function optimization problems in science and engineering .
{ "id": "C0031809", "pos": [ 47, 55 ], "name": "physical" }
{ "id": "C0185125", "pos": [ 117, 129 ], "name": "applications" }
0NA
Their extraction through endoscopy or most often surgery is necessary for a proper recovery .
{ "id": "C0185115", "pos": [ 6, 16 ], "name": "extraction" }
{ "id": "C0014245", "pos": [ 25, 34 ], "name": "endoscopy" }
0NA
Prenatal choline supplementation could attenuate the spatial learning deficits caused by prenatal protein malnutrition by increasing brain choline , betaine and phospholipids and by influencing the hippocampus structure .
{ "id": "C0006104", "pos": [ 133, 138 ], "name": "brain" }
{ "id": "C0019564", "pos": [ 198, 209 ], "name": "hippocampus" }
0NA
Cefpirome was compared to cefazolin , cefuroxime , ceftazidime , ceftriaxone , aztreonam , imipenem , ticarcillin , tobramycin and ciprofloxacin .
{ "id": "C0020933", "pos": [ 91, 99 ], "name": "imipenem" }
{ "id": "C0007559", "pos": [ 51, 62 ], "name": "ceftazidime" }
0NA
The DOTA linkage was installed at a mechanism-based strategic location in the pantoprazole molecule to minimize a possible negative effect of the structural modification on the drug .
{ "id": "C0013227", "pos": [ 177, 181 ], "name": "drug" }
{ "id": "C0081876", "pos": [ 78, 90 ], "name": "pantoprazole" }
0NA
These are the following : 1 ) factors that cause reparable hepatic injury -- including partial hepatectomy , CC14 , and bile duct ligation , and 2 ) continuous perfusion of angiotensin II .
{ "id": "C0031001", "pos": [ 160, 169 ], "name": "perfusion" }
{ "id": "C0019144", "pos": [ 95, 106 ], "name": "hepatectomy" }
0NA
Rats were given moniliformin orally at the dosage of 6 mg.kg-1 once daily for 56 d. Lesions of mitochondria and myofibrils were relatively mild .
{ "id": "C0221198", "pos": [ 84, 91 ], "name": "Lesions" }
{ "id": "C0226896", "pos": [ 29, 35 ], "name": "orally" }
0NA
A mucinous cystadenoma of the ovary weighing more than 20 kg was removed with laparotomy .
{ "id": "C0029939", "pos": [ 30, 35 ], "name": "ovary" }
{ "id": "C0023038", "pos": [ 78, 88 ], "name": "laparotomy" }
0NA
C-29 caused less damage than either metrizamide or meglumine iothalamate .
{ "id": "C0010957", "pos": [ 17, 23 ], "name": "damage" }
{ "id": "C0025869", "pos": [ 36, 47 ], "name": "metrizamide" }
0NA
Myocardial HIF-1alpha expression , and plasma ET-1 and creatine kinase ( CK ) levels were measured .
{ "id": "C0027061", "pos": [ 0, 10 ], "name": "Myocardial" }
{ "id": "C0032105", "pos": [ 39, 45 ], "name": "plasma" }
0NA
At a second laparotomy , it was assessed which follicles had ovulated .
{ "id": "C0221971", "pos": [ 47, 56 ], "name": "follicles" }
{ "id": "C0023038", "pos": [ 12, 22 ], "name": "laparotomy" }
0NA
Group A2 received diclofenac suppository .
{ "id": "C0031246", "pos": [ 29, 40 ], "name": "suppository" }
{ "id": "C0012091", "pos": [ 18, 28 ], "name": "diclofenac" }
0NA
The most frequently diagnosed form of CTCL , mycosis fungoides ( MF ) , is a primarily indolent malignancy that is most frequently managed using a variety of milder treatment approaches , such as skin-directed therapies or biologic systemic therapies .
{ "id": "C0026948", "pos": [ 45, 62 ], "name": "mycosis fungoides" }
{ "id": "C0079773", "pos": [ 38, 42 ], "name": "CTCL" }
0NA
We summarise recent data on the mechanisms by which latent GLI proteins are activated in response to stimulation of Hedgehog signalling .
{ "id": "C1292856", "pos": [ 101, 112 ], "name": "stimulation" }
{ "id": "C0033684", "pos": [ 63, 71 ], "name": "proteins" }
0NA
Encapsulated haemorrhage was present in the retroperitoneum around the kidneys .
{ "id": "C0022646", "pos": [ 71, 78 ], "name": "kidneys" }
{ "id": "C0019080", "pos": [ 13, 24 ], "name": "haemorrhage" }
0NA
In this study a colorimetric aptasensor was designed for sensitive , selective and fast detection of tetracycline based on triple-helix molecular switch ( THMS ) and gold nanoparticles ( AuNPs ) .
{ "id": "C0039644", "pos": [ 101, 113 ], "name": "tetracycline" }
{ "id": "C0020517", "pos": [ 57, 66 ], "name": "sensitive" }
0NA
The calcium antagonist , nifedipine , abolished the contractile effects of NPY and the NPY-induced enhancement of NA contractions but did not influence the prejunctional inhibition of [3H]NA release .
{ "id": "C0006684", "pos": [ 4, 22 ], "name": "calcium antagonist" }
{ "id": "C1627358", "pos": [ 99, 110 ], "name": "enhancement" }
0NA
Protein tyrosine kinases ( PTKs ) play a central role in the modulation of a wide variety of cellular events such as differentiation , proliferation and metabolism , and their unregulated activation can lead to various diseases including cancer and diabetes .
{ "id": "C0006826", "pos": [ 238, 244 ], "name": "cancer" }
{ "id": "C0012634", "pos": [ 219, 227 ], "name": "diseases" }
0NA
This is in contrast to the responses of a population of neurones recorded in the hypothalamus , which only occur to the taste of food when the monkey is hungry .
{ "id": "C0020663", "pos": [ 81, 93 ], "name": "hypothalamus" }
{ "id": "C0039336", "pos": [ 120, 125 ], "name": "taste" }
0NA
Visual acuity in her right eye ( OD ) was hand motion and left eye ( OS ) was counting fingers .
{ "id": "C0229090", "pos": [ 58, 66 ], "name": "left eye" }
{ "id": "C0229089", "pos": [ 21, 30 ], "name": "right eye" }
0NA
We gave a regimen of cyclophosphamide and antithymocyte globulin ( CY/ATG ) to six patients with early stage severe aplastic anemia ( SAA ) transplanted with marrow from alternative donors .
{ "id": "C0040732", "pos": [ 140, 152 ], "name": "transplanted" }
{ "id": "C0002874", "pos": [ 116, 131 ], "name": "aplastic anemia" }
0NA
Single-freeze cryoablation results in necrosis of intralesional hepatic parenchyma without added benefit from repeat freezing .
{ "id": "C0027540", "pos": [ 38, 46 ], "name": "necrosis" }
{ "id": "C0736268", "pos": [ 64, 82 ], "name": "hepatic parenchyma" }
0NA
Treatment with stimulant medications , which include methylphenidate and amphetamine , typically requires multiple daily doses to maintain efficacy .
{ "id": "C0013227", "pos": [ 25, 36 ], "name": "medications" }
{ "id": "C0025810", "pos": [ 53, 68 ], "name": "methylphenidate" }
0NA
Infections after osteosynthesis are a   feared complication of the surgical treatment of fractures and should be dealt with by a   multidisciplinary team .
{ "id": "C0016658", "pos": [ 89, 98 ], "name": "fractures" }
{ "id": "C0016642", "pos": [ 17, 31 ], "name": "osteosynthesis" }
8direct_morphology_of
Kidney transplantation , haemodialysis and peritoneal dialysis are currently the gold standard of renal replacement therapy .
{ "id": "C0031153", "pos": [ 43, 53 ], "name": "peritoneal" }
{ "id": "C0022671", "pos": [ 0, 22 ], "name": "Kidney transplantation" }
0NA
This study was carried out to investigate leakage/transport across the bag material of six outer cryopreservation bags in common use within NHS Blood and Transplant .
{ "id": "C0005767", "pos": [ 144, 149 ], "name": "Blood" }
{ "id": "C0040732", "pos": [ 154, 164 ], "name": "Transplant" }
0NA
Repeated exposure to organophosphate-based pesticides appears to be associated with subtle changes in the nervous system .
{ "id": "C0027763", "pos": [ 106, 120 ], "name": "nervous system" }
{ "id": "C0274281", "pos": [ 9, 17 ], "name": "exposure" }
0NA
The antibody obtained was capable of detecting human and mouse PXR with high specificity and sensitivity .
{ "id": "C0003241", "pos": [ 4, 12 ], "name": "antibody" }
{ "id": "C0020517", "pos": [ 93, 104 ], "name": "sensitivity" }
0NA
Hemodynamic parameters , such as aortic characteristic impedance , wave transit time , and arterial load compliance , were inferred from the aortic pressure and flow signals to describe the pulsatile nature of blood flow in the vasculature .
{ "id": "C0003842", "pos": [ 91, 99 ], "name": "arterial" }
{ "id": "C0232338", "pos": [ 210, 220 ], "name": "blood flow" }
0NA
Numerous epidemiologic studies have demonstrated that regular physical activity convincingly reduces risk for colon cancer , probably for endometrium and postmenopausal breast cancer , and possibly for premenopausal breast , prostate , lung , and pancreas cancer .
{ "id": "C0006141", "pos": [ 216, 222 ], "name": "breast" }
{ "id": "C0006142", "pos": [ 169, 182 ], "name": "breast cancer" }
11finding_site_of
Of patients undergoing operation more than 15 years ago , 45 % ( 9/20 ) are still alive .
{ "id": "C2584946", "pos": [ 82, 87 ], "name": "alive" }
{ "id": "C0543467", "pos": [ 23, 32 ], "name": "operation" }
0NA
In phase I of the BOND project , 6 nutrients ( iodine , vitamin A , iron , zinc , folate , and vitamin B-12 ) were selected for their high public health importance because they typify the challenges faced by users in the selection , use , and interpretation of biomarkers .
{ "id": "C0043481", "pos": [ 75, 79 ], "name": "zinc" }
{ "id": "C0021968", "pos": [ 47, 53 ], "name": "iodine" }
0NA
The inhibition of the proliferation rate of the immortalized human cell line ECV 304 after oxidant damage by oxygen radicals generated in a hypoxanthin-xanthine oxidase system and the protection provided by various propolis extracts was determined .
{ "id": "C0010957", "pos": [ 99, 105 ], "name": "damage" }
{ "id": "C0033488", "pos": [ 215, 223 ], "name": "propolis" }
0NA
In carrying out HTCA according to the Hamburger-Salmon method , the cell suspension samples following exposure to anti-tumor agents ( MMC , L-PAM , ADM , CDDP ) were cultivated in test tubes for 3 - 8 hours and stained by the Papanicolaou and Giemsa methods .
{ "id": "C0003392", "pos": [ 114, 131 ], "name": "anti-tumor agents" }
{ "id": "C0013089", "pos": [ 148, 151 ], "name": "ADM" }
0NA
Falls accounted for 49 % of the fractures , varying from 77 % in one-year-olds to 26 % in eight-year-old children .
{ "id": "C0016658", "pos": [ 32, 41 ], "name": "fractures" }
{ "id": "C0000921", "pos": [ 0, 5 ], "name": "Falls" }
0NA
Of interest , the prognostic analysis of breast and colon cancers revealed favorable survival and no lymphogenous metastasis in patients whose cancer expressed tenascin strongly .
{ "id": "C0006141", "pos": [ 41, 47 ], "name": "breast" }
{ "id": "C0007102", "pos": [ 52, 65 ], "name": "colon cancers" }
0NA
Stimulation of the immune system by targeting the PD-1/PD-L1 pathway can result in activation of anti-tumor immunity .
{ "id": "C1292856", "pos": [ 0, 11 ], "name": "Stimulation" }
{ "id": "C0020964", "pos": [ 108, 116 ], "name": "immunity" }
0NA
The commonest symptoms were those of subacute spinal cord compression ( mean duration , 2.3 months ) with progressive lower-limb weakness ( 94 % ) , paresthesia , and bowel and bladder dysfunction .
{ "id": "C0021853", "pos": [ 167, 172 ], "name": "bowel" }
{ "id": "C0030554", "pos": [ 149, 160 ], "name": "paresthesia" }
0NA
A sandwich enzyme-linked immunosorbent assay technique was used to assay the circulating PAPP-A. Plaque characteristics of culprit lesion were analyzed for UA patients with various PAPP-A levels .
{ "id": "C0221198", "pos": [ 131, 137 ], "name": "lesion" }
{ "id": "C0011389", "pos": [ 97, 103 ], "name": "Plaque" }
0NA
Brazilin prevented joint destruction , surface erosion , and enhanced bone formation as revealed by microstructural examinations .
{ "id": "C0333307", "pos": [ 47, 54 ], "name": "erosion" }
{ "id": "C0029433", "pos": [ 70, 84 ], "name": "bone formation" }
0NA
No hindlimb malformations were induced .
{ "id": "C0000768", "pos": [ 12, 25 ], "name": "malformations" }
{ "id": "C0023216", "pos": [ 3, 11 ], "name": "hindlimb" }
0NA
To study the role of TR3 in atherosclerosis , we generated transgenic mice in which promoter sequences were applied that direct expression of the transgenes to SMC of the arterial tree .
{ "id": "C0003842", "pos": [ 171, 184 ], "name": "arterial tree" }
{ "id": "C0003850", "pos": [ 28, 43 ], "name": "atherosclerosis" }
11finding_site_of
Serologic studies and clinical features indicate that the thrombocytopenia was due to an autoimmune process , presumably similar to that induced by the chemically similar drug methyldopa .
{ "id": "C0220806", "pos": [ 152, 162 ], "name": "chemically" }
{ "id": "C0040034", "pos": [ 58, 74 ], "name": "thrombocytopenia" }
0NA
The importance of this pathway on intestinal allograft rejection was examined in this study .
{ "id": "C0021853", "pos": [ 34, 44 ], "name": "intestinal" }
{ "id": "C0040739", "pos": [ 45, 54 ], "name": "allograft" }
0NA
A total of 103 specimens were diagnosed as tubercular lesion by histological evaluation in the department of pathology , Mymensingh Medical College and a private laboratory during the period from January 1997 to August 1998 .
{ "id": "C0221198", "pos": [ 54, 60 ], "name": "lesion" }
{ "id": "C0025344", "pos": [ 184, 190 ], "name": "period" }
0NA
A 79-year-old HCV-positive man was hospitalized for severe abdominal pain , nausea and vomiting , 15 days after starting indomethacin for back pain .
{ "id": "C0205082", "pos": [ 52, 58 ], "name": "severe" }
{ "id": "C0000737", "pos": [ 59, 73 ], "name": "abdominal pain" }
0NA
Blood could be visualized in the cisterns of 18 of 32 examinations performed within five days of the hemorrhage all having aneurysms .
{ "id": "C0031809", "pos": [ 54, 66 ], "name": "examinations" }
{ "id": "C0002940", "pos": [ 123, 132 ], "name": "aneurysms" }
0NA
Using ultrasound , PLR-BAD and FMD induced by release of arterial cuff occlusion were measured .
{ "id": "C0041618", "pos": [ 6, 16 ], "name": "ultrasound" }
{ "id": "C0016052", "pos": [ 31, 34 ], "name": "FMD" }
0NA
The distribution pattern of diazepam and N-desmethyldiazepam offers a rationale for its efficacy in inhibiting seizures spreading and for the lack of effect on primary foci discharges .
{ "id": "C0012010", "pos": [ 28, 36 ], "name": "diazepam" }
{ "id": "C0036572", "pos": [ 111, 119 ], "name": "seizures" }
0NA
Newly diagnosed hypertension , bone fractures , postcapsular cataracts , myopathy , and diabetes occurred in less than 5 percent of the subjects , and the diagnoses were equally distributed between the groups .
{ "id": "C0016658", "pos": [ 31, 45 ], "name": "bone fractures" }
{ "id": "C0026848", "pos": [ 73, 81 ], "name": "myopathy" }
0NA
This study supports our previously documented clinical experience that the use of chondrosynthetic techniques is almost complication-free and is an ideal system for performing precise anatomical reconstruction of the laryngeal skeleton .
{ "id": "C0023078", "pos": [ 217, 226 ], "name": "laryngeal" }
{ "id": "C0037253", "pos": [ 227, 235 ], "name": "skeleton" }
0NA
A new prototype ( hardware and software ) for monitoring eye movements using a noninvasive technique for gated linac-based stereotactic radiotherapy ( SRT ) of uveal melanoma was developed .
{ "id": "C0015392", "pos": [ 57, 60 ], "name": "eye" }
{ "id": "C0150369", "pos": [ 46, 56 ], "name": "monitoring" }
0NA
The relationship between the pharmacokinetics and the therapeutic efficacy and safety of the serotonin selective reuptake inhibitors ( SSRIs ) is considered with particular attention to fluoxetine , fluvoxamine , sertraline , and paroxetine .
{ "id": "C0036751", "pos": [ 93, 102 ], "name": "serotonin" }
{ "id": "C0074393", "pos": [ 213, 223 ], "name": "sertraline" }
0NA
The concept of normoxic cardiopulmonary bypass may be applied to surgical advantage during cardiac operations .
{ "id": "C0007202", "pos": [ 24, 46 ], "name": "cardiopulmonary bypass" }
{ "id": "C0543467", "pos": [ 65, 73 ], "name": "surgical" }
0NA
Dementia types were as follows : 73 % Alzheimer disease , 24 % vascular and mixed dementia , and 3 % Parkinson dementia .
{ "id": "C0005847", "pos": [ 63, 71 ], "name": "vascular" }
{ "id": "C3532942", "pos": [ 76, 90 ], "name": "mixed dementia" }
0NA
We concluded that prophylactic doses of 10 or 40 micrograms kg-1 lead to a safe and satisfactory degree of control of nausea and vomiting induced by high-dose cisplatin .
{ "id": "C0008838", "pos": [ 159, 168 ], "name": "cisplatin" }
{ "id": "C0042963", "pos": [ 129, 137 ], "name": "vomiting" }
0NA