| {"claim": "Double balloon enteroscopy is efficacious and safe in a community setting.", "verdict": "supports", "evidence": [23831910]} | |
| {"claim": "The association between patient characteristics and the comparative safety of infliximab and etanercept on the risk of serious infections may vary.", "verdict": "supports", "evidence": [22411435]} | |
| {"claim": "Portable ultrasonography is accurate in the evaluation of Schanz pin placement during extremity fracture fixation in austere environments.", "verdict": "supports", "evidence": [24352924]} | |
| {"claim": "Intensive chemotherapy is safe for rural cancer patients.", "verdict": "supports", "evidence": [23347337]} | |
| {"claim": "External palliative radiotherapy for gallbladder carcinoma is effective.", "verdict": "supports", "evidence": [11799314]} | |
| {"claim": "There may be a difference in deflation rates between 500 prefilled textured saline breast implants and 500 standard textured saline breast implants.", "verdict": "supports", "evidence": [16772913]} | |
| {"claim": "Performance measurement systems are useful.", "verdict": "supports", "evidence": [28143468]} | |
| {"claim": "Lower limb fractures should be treated surgically in patients with chronic spinal injuries.", "verdict": "supports", "evidence": [27908583]} | |
| {"claim": "Teleoncology models of care enable safe delivery of chemotherapy in rural towns.", "verdict": "supports", "evidence": [26561905]} | |
| {"claim": "Grandmultiparity is an independent risk factor for adverse perinatal outcomes.", "verdict": "supports", "evidence": [16147837]} | |
| {"claim": "There is a model of healing of Los Angeles grades C and D reflux oesophagitis, and it explores whether there is an optimal time of acid suppression for maximal healing.", "verdict": "supports", "evidence": [20497146]} | |
| {"claim": "Quilting suture prevents seroma in abdominoplasty.", "verdict": "supports", "evidence": [17312514]} | |
| {"claim": "Intraoperative precursor events are associated with postoperative major adverse events.", "verdict": "supports", "evidence": [23870157]} | |
| {"claim": "There are different levels of risk for transition to psychosis in the Ultra high risk (UHR) for psychosis criteria.", "verdict": "supports", "evidence": [21074975]} | |
| {"claim": "Memory-provoked rCBF-SPECT is a diagnostic tool in Alzheimer's disease.", "verdict": "supports", "evidence": [16151770]} | |
| {"claim": "Viral infections do have a role in benign paroxysmal positional vertigo.", "verdict": "supports", "evidence": [26601554]} | |
| {"claim": "Topical N-acetylcysteine application after myringotomy causes severe otorrhea.", "verdict": "supports", "evidence": [17483607]} | |
| {"claim": "Edaravone offers protection against attenuation of ischemia/reperfusion-induced ovarian damage in rats.", "verdict": "supports", "evidence": [23899611]} | |
| {"claim": "Orthostatic myoclonus is an underrecognized cause of unsteadiness.", "verdict": "supports", "evidence": [23916653]} | |
| {"claim": "Students' scores on preclerkship clinical performance examinations can predict that they will fail a senior clinical performance examination.", "verdict": "supports", "evidence": [21346501]} | |
| {"claim": "Sex does affect the outcome of laparoscopic cholecystectomy.", "verdict": "supports", "evidence": [22970993]} | |
| {"claim": "Adult body circumferences are associated with height.", "verdict": "supports", "evidence": [21123461]} | |
| {"claim": "The scale of identification of racial disparities in breast cancer mortality matters.", "verdict": "supports", "evidence": [20602784]} | |
| {"claim": "Severe macrosomia is manifested at 11-14 weeks of gestation.", "verdict": "supports", "evidence": [18570208]} | |
| {"claim": "Infundibular height can predict the clearance of lower pole calyceal stone after extracorporeal shockwave lithotripsy.", "verdict": "supports", "evidence": [19409117]} | |
| {"claim": "Motion perception deficit in schizophrenia is a consequence of eye-tracking abnormality.", "verdict": "supports", "evidence": [19054501]} | |
| {"claim": "IgM-enriched immunoglobulins are an effective adjuvant in septic VLBW infants.", "verdict": "supports", "evidence": [24098953]} | |
| {"claim": "The standard of effective analgesia is reachable in all women through the implementation of epidural analgesia for labor.", "verdict": "supports", "evidence": [23690198]} | |
| {"claim": "Some U.S. states have higher/lower injury mortality rates than others.", "verdict": "supports", "evidence": [15995461]} | |
| {"claim": "Predilatation in transcatheter aortic valve implantation can be omitted.", "verdict": "supports", "evidence": [27491658]} | |
| {"claim": "A physician's specialty influences the recording of medication history in patients' case notes.", "verdict": "supports", "evidence": [18537964]} | |
| {"claim": "Mossy fibers release GABA.", "verdict": "supports", "evidence": [12121321]} | |
| {"claim": "Sonographic needle guidance affects the clinical outcome of intraarticular injections.", "verdict": "supports", "evidence": [19648304]} | |
| {"claim": "The instrumental activities of daily living can predict dementia at 1- and 2-year follow-up.", "verdict": "supports", "evidence": [22188074]} | |
| {"claim": "Automatic transmission improves driving behavior in older drivers.", "verdict": "supports", "evidence": [21865668]} | |
| {"claim": "The SYNTAX score predicts in-hospital outcomes in patients with ST elevation myocardial infarction undergoing primary percutaneous coronary intervention.", "verdict": "supports", "evidence": [24671913]} | |
| {"claim": "Cytokines have a role in epilepsy.", "verdict": "supports", "evidence": [18783922]} | |
| {"claim": "Preloading with colloids prevents hemodynamic changes when neurosurgical patients are subsequently changed to the seated position.", "verdict": "supports", "evidence": [15962678]} | |
| {"claim": "Family practice at residency teaching sites reflects community practice.", "verdict": "supports", "evidence": [8245806]} | |
| {"claim": "Spontaneous remission occurs in polyarteritis nodosa.", "verdict": "supports", "evidence": [28177278]} | |
| {"claim": "Glomerular hyperfiltration in pregnancy does not damage the kidney in women with more parities.", "verdict": "refutes", "evidence": [19575307]} | |
| {"claim": "Frozen section does not alter surgical management of multinodular thyroid disease.", "verdict": "refutes", "evidence": [17054994]} | |
| {"claim": "Many colorectal cancers are due to missed adenomas.", "verdict": "refutes", "evidence": [19237087]} | |
| {"claim": "Mandibular depiction can be improved by changing the thickness of double-oblique computed tomography images.", "verdict": "refutes", "evidence": [18784527]} | |
| {"claim": "The preoperative staging of patients with liver metastases of colorectal carcinoma includes determining if PET/CT truly provides additional information compared to multidetector CT.", "verdict": "refutes", "evidence": [21431987]} | |
| {"claim": "Arch form is influenced by sagittal molar relationship or Bolton tooth-size discrepancy.", "verdict": "refutes", "evidence": [26113007]} | |
| {"claim": "All patients with biliary atresia should undergo a portoenterostomy.", "verdict": "refutes", "evidence": [9044116]} | |
| {"claim": "Sports medicine journals are relevant and applicable to practitioners and athletes.", "verdict": "refutes", "evidence": [15388567]} | |
| {"claim": "Prerecorded lecture VODcasts affect the lecture attendance of first-year pre-clinical Graduate Entry to Medicine students.", "verdict": "refutes", "evidence": [28027677]} | |
| {"claim": "Unsafe sexual behaviour is increasing among HIV-infected individuals.", "verdict": "refutes", "evidence": [15280782]} | |
| {"claim": "Early postoperative oral intake should be limited to laparoscopy.", "verdict": "refutes", "evidence": [8200238]} | |
| {"claim": "Growth hormone replacement therapy reduces mortality in adults with growth hormone deficiency.", "verdict": "refutes", "evidence": [21849531]} | |
| {"claim": "Chronic functional somatic symptoms are a single syndrome.", "verdict": "refutes", "evidence": [15588538]} | |
| {"claim": "Episodic migraineurs selectively attend to headache-related visual stimuli.", "verdict": "refutes", "evidence": [23252468]} | |
| {"claim": "\"Wandering and physically nonaggressive agitation are equivalent.\"", "verdict": "refutes", "evidence": [18378554]} | |
| {"claim": "Diffusion-weighted imaging is a significant indicator of the development of vascularization in hypovascular hepatocellular lesions.", "verdict": "refutes", "evidence": [24799031]} | |
| {"claim": "Quantitative left ventricular regional wall motion changes after fibrous tissue resection in endomyocardial fibrosis.", "verdict": "refutes", "evidence": [19142546]} | |
| {"claim": "Normal knee kinematics can be restored with unicompartmental knee replacement.", "verdict": "refutes", "evidence": [15687156]} | |
| {"claim": "The sex of acute stroke patients influences the effectiveness of rt-PA.", "verdict": "refutes", "evidence": [24669960]} | |
| {"claim": "Pain intensity predicts a poor opioid response in cancer patients.", "verdict": "refutes", "evidence": [21256734]} | |
| {"claim": "The DdrB protein from Deinococcus radiodurans functions as a pentamer.", "verdict": "supports", "evidence": [20129942]} | |
| {"claim": "Cell autonomous sex determination in somatic cells occurs in Galliformes.", "verdict": "supports", "evidence": [20220842]} | |
| {"claim": "In melanoma, anti-CTLA-4 treatment reinvigorates exhausted PD-1+Eomes+CD8 T cells.", "verdict": "supports", "evidence": [25754329]} | |
| {"claim": "N348I mutations cause resistance to zidovudine (AZT).", "verdict": "supports", "evidence": [18052601]} | |
| {"claim": "PKG-la plays an essential role in expression of spinal long term potentiation in PGK-la knockout mice.", "verdict": "supports", "evidence": [22427743]} | |
| {"claim": "Osteocytes have an essential role in G-CSF induced HSPC mobilization.", "verdict": "supports", "evidence": [23746979]} | |
| {"claim": "AIRE is expressed in some skin tumors.", "verdict": "supports", "evidence": [26168014]} | |
| {"claim": "Varying expression levels of EBI2 affect the positioning and migration of B cells.", "verdict": "supports", "evidence": [19615922, 25852561]} | |
| {"claim": "Genes involved in pre-mRNA splicing have a significant impact on genome stability.", "verdict": "supports", "evidence": [19647519]} | |
| {"claim": "The tip of the inner tube of the toxic type VI secretion system (T6SS) antibacterial effector in Escherichia coli (E. coli) carries toxic effector proteins.", "verdict": "supports", "evidence": [23925114]} | |
| {"claim": "NR5A2 is important in development of endometrial tissues.", "verdict": "supports", "evidence": [23817023]} | |
| {"claim": "The relationship between a breast cancer patient's capacity to metabolize tamoxifen and treatment outcome is dependent on the patient's genetic make-up.", "verdict": "supports", "evidence": [19809024]} | |
| {"claim": "S-nitrosylated GAPDH physiologically transnitrosylates histone deacetylases.", "verdict": "supports", "evidence": [20972425]} | |
| {"claim": "Omnivores produce more trimethylamine N-oxide from dietary I-carnitine than vegans.", "verdict": "supports", "evidence": [23563705]} | |
| {"claim": "Pro-inflammatory cytokines are up regulated during tumor development.", "verdict": "supports", "evidence": [16891858]} | |
| {"claim": "Human T-lymphotropic virus type-I-associated myelopathy / tropical spastic paraparesis (HAM/TSP) patients produce Immunoglobulin G (IgG) antibodies which cross-react with an immunodominant epitope in Tax.", "verdict": "supports", "evidence": [11984596]} | |
| {"claim": "The minor G allele of FOXO3 up-regulates IL-10.", "verdict": "supports", "evidence": [24035192]} | |
| {"claim": "A strong bias in the phage genome locations where the spacers were derived has been observed in many CRISPR subtypes that confer the immunity to phage.", "verdict": "supports", "evidence": [23385575]} | |
| {"claim": "Proteins synthesized at the growth cone are ubiquitinated at a higher rate than proteins from the cell body.", "verdict": "supports", "evidence": [25901863]} | |
| {"claim": "Nanoparticles can be targeted against specific cell types by incorporating aptamers into lipid nanoparticles.", "verdict": "supports", "evidence": [25665179]} | |
| {"claim": "The YAP1 and TEAD complex tanslocates into the nucleus where it interacts with transcription factors and DNA-binding proteins that modulate target gene transcription.", "verdict": "supports", "evidence": [28752853]} | |
| {"claim": "The sliding activity of kinesin-8 protein Kip3 promotes bipolar spindle assembly.", "verdict": "supports", "evidence": [23851487]} | |
| {"claim": "1,000 genomes project enables mapping of genetic sequence variation consisting of rare variants with larger penetrance effects than common variants.", "verdict": "supports", "evidence": [20126254]} | |
| {"claim": "MICAL redox enzymes regulate actin dynamics.", "verdict": "supports", "evidence": [17350233, 22331357, 21521879]} | |
| {"claim": "Two variants of chromosome 6q21 are associated with radiation therapy-induced second malignancies in pediatric Hodgkin lymphoma patients.", "verdict": "supports", "evidence": [21785431]} | |
| {"claim": "Progerin induces premature aging in stem cells.", "verdict": "supports", "evidence": [24315443]} | |
| {"claim": "Mice lacking Sirt1 in Sf1-expressing neurons have increased susceptibility to diet-induced obesity and insulin resistance.", "verdict": "supports", "evidence": [21907137]} | |
| {"claim": "ALDH1 expression is associated with poorer prognosis in breast cancer.", "verdict": "supports", "evidence": [18371393]} | |
| {"claim": "Participating in six months of physical activity improves cognitive functioning.", "verdict": "supports", "evidence": [18768414]} | |
| {"claim": "miRNAs enforce homeostasis by suppressing low-level ''leaky'' transcription.", "verdict": "supports", "evidence": [22541426]} | |
| {"claim": "The repeat-variable diresidue (RVD) in the loop of Transcription-Activator Like (TAL) effectors specifies the nucleotides-amino acid contact at the target promoter element.", "verdict": "supports", "evidence": [22223738]} | |
| {"claim": "Teaching hospitals do not provide better care than non-teaching hospitals.", "verdict": "supports", "evidence": [16968119]} | |
| {"claim": "Antiretroviral therapy reduces rates of tuberculosis across a broad range of CD4 strata.", "verdict": "supports", "evidence": [22911011]} | |
| {"claim": "Vitamin D deficiency effects the term of delivery.", "verdict": "supports", "evidence": [23533188]} | |
| {"claim": "The generation of reactive oxygen species by activated oncogenes contributes to the increased genomic instability of leukaemia cells.", "verdict": "supports", "evidence": [15304390]} | |
| {"claim": "Trans-acting factors, such as lncRNAs, influence mRNA translation.", "verdict": "supports", "evidence": [22841487]} | |
| {"claim": "High levels of CRP lead to a higher risk of exacerbations in chronic obstructive pulmonary disease (COPD).", "verdict": "supports", "evidence": [23757083]} | |
| {"claim": "The DESMOND program demonstrates no significant impact on biochemical outcomes.", "verdict": "supports", "evidence": [22539172]} | |
| {"claim": "Pseudogene PTENP1 regulates the expression of PTEN by functioning as an miRNA decoy.", "verdict": "supports", "evidence": [20577206]} | |
| {"claim": "1/2000 in UK have abnormal PrP positivity.", "verdict": "supports", "evidence": [24129059]} | |
| {"claim": "Hyperfibrinogenemia decreases rates of femoropopliteal bypass thrombosis.", "verdict": "refutes", "evidence": [2508847]} | |
| {"claim": "Incidence rates of cervical cancer have increased due to nationwide screening programs based primarily on cytology to detect uterine cervical cancer.", "verdict": "refutes", "evidence": [18067129]} | |
| {"claim": "Basophils counteract disease development in patients with systemic lupus erythematosus (SLE).", "verdict": "refutes", "evidence": [20512127]} | |
| {"claim": "Early patent ductus ateriosus (PDA) screening increases in-hospital mortality.", "verdict": "refutes", "evidence": [26103028]} | |
| {"claim": "Hypothalamic glutamate neurotransmission is unrelated to energy balance.", "verdict": "refutes", "evidence": [24315371, 17488640]} | |
| {"claim": "Noninvasive positive pressure ventilation is not predictive of acute respiratory failure after solid organ transplantation.", "verdict": "refutes", "evidence": [10634340]} | |
| {"claim": "MafA ubiquitination decreases the recruitment of coavtivator P/CAF by MafA.", "verdict": "refutes", "evidence": [18042454]} | |
| {"claim": "Low nucleosome occupancy correlates with low methylation levels across species.", "verdict": "refutes", "evidence": [24630728]} | |
| {"claim": "LDL cholesterol has no involvement in the development of cardiovascular disease.", "verdict": "refutes", "evidence": [18262040]} | |
| {"claim": "One in two surgical randomized controlled trials are discontinued early.", "verdict": "refutes", "evidence": [25491195]} | |
| {"claim": "Pioglitazone use is not associated with an increased risk of prostate cancer.", "verdict": "refutes", "evidence": [26197187]} | |
| {"claim": "Birth-weight is negatively associated with breast cancer.", "verdict": "refutes", "evidence": [18828667, 16823839, 18054879, 18205956]} | |
| {"claim": "JMJD6 slows the hydroxylation of C-terminal lysine", "verdict": "refutes", "evidence": [24667498]} | |
| {"claim": "Microcin J25 encourages nucleoside triphosphate (NTP) binding.", "verdict": "refutes", "evidence": [15200952]} | |
| {"claim": "Active Ly49Q prevents neutrophil polarization.", "verdict": "refutes", "evidence": [20153219]} | |
| {"claim": "T regulatory cells (tTregs) lacking \u03b1v\u03b28 are more adept at suppressing pathogenic T-cell responses during active inflammation.", "verdict": "refutes", "evidence": [25979421]} | |
| {"claim": "TNFAIP3 is a tumor suppressor in glioblastoma.", "verdict": "refutes", "evidence": [20186265]} | |
| {"claim": "Vitamin D deficiency is unrelated to birth weight.", "verdict": "refutes", "evidence": [23533188]} | |
| {"claim": "A country's Vaccine Alliance (GAVI) eligibility is not indictivate of accelerated adoption of the Hub vaccine.", "verdict": "refutes", "evidence": [20305714]} | |
| {"claim": "A diminished ovarian reserve is a very strong indicator of infertility, even in an a priori non-infertile population.", "verdict": "refutes", "evidence": [29049585]} | |