### Clue: 5 across pinching a 5 across from behind — that's tame! (8)
### Answer: HUMANISE 
 ### Explanation: Definition: tame
An envelope ('pinching') of 'a' plus NIS, a reversal ('from behind') of SIN ('5 across', CARDINAL, the former Archbishop of Manila, or allusively) in HUME (another CARDINAL),