### Clue: High priest number two holding mass for stricken city (7)
### Answer: POMPEII 
 ### Explanation: Definition: stricken city
 [POPE(the highest/supreme priest of the Roman Catholic Church, or, in other churches, one having a similar position) + II(Roman numeral for the number two)] **containing**(holding) M(symbol for "mass" in physics).
Defn: …, buried by an eruption of Mt. Vesuvius, and remarkably excavated: