### Clue: Too many drugs and tablets going to South American port (6)
### Answer: ODESSA 
 ### Explanation: Definition: port
 OD(abbrev. for "overdose";intake of too many drugs) **plus**(going to) E(slang for Ecstasy, the drug commonly in tablet form, from which comes the nickname "tab")S + S.A.(abbrev. for South American).