### Clue: Element of organ infection and reduced energy associated with smoker (4,4)
### Answer: FLUE PIPE 
 ### Explanation: Definition: Element of organ
 FLU(short for "influenza"/a highly contagious viral infection) **plus**(and) E(abbrev. for /reduced "energy" in physics) **plus**(associated with) PIPE(smoker/that which produces smoke/a device for smoking tobacco).