### Clue: Large-scale course briefly a focus for seismologist (9)
### Answer: EPICENTRE 
 ### Explanation: Definition: a focus for seismologist
 EPIC(large-scale/grand) + "entrée"(the main dish, or sometimes the dish before the main dish, of a meal) **minus its last letter**(briefly).
Defn: The point on the earth's surface above the origin of an earthquake, of interest to/a focus for seismologists.