### Clue: One searching smallest room, say, for complaint in the Observer (7)
### Answer: LEUCOMA 
 ### Explanation: Definition: complaint in the Observer
 **Homophone of**(…, say) ["loo-"(the toilet/euphemistically, the smallest room) "-comber"(one searching carefully and systematically) – cf. "beachcomber", say].
Defn: A complaint/medical problem with the eye/one's observer, viz. a white opacity in the cornea.