### Clue: River of Eden towards the end (4)
### Answer: AVON 
 ### Explanation: Definition: River
  Not a reference to the Garden, as one would expect from this setter (that comes later), but to Anthony Eden, former British PM who was made 1st Earl of Avon in the latter part,towards the end of his life – I'm not sure whether I've missed another significance in the last 3 words of the clue. 
Answer: Name of many rivers in England (not to mention in other countries), most famous of which is Shakespeare's.