### Clue: One's ending with muck around one — as a result of this? (6)
### Answer: EMESIS 
 ### Explanation: Definition: this
  E(last letter,ending of "One") **plus**(with) [MESS(muck,dirty stuff ) **containing**(around) I(Roman numeral for "one")].
Answer: The act or process of vomiting, that might,? leave muck around one.  A clever WIWD (wordplay intertwined with definition) clue.