### Clue: Evacuation from east? So be it to the west (5)
### Answer: ENEMA 
 ### Explanation: Definition: Evacuation
 E(abbrev. for "east") + **reversal of**(…: to the west, from the east, in an across clue) AMEN(word meaning "so be it", uttered at the end of a prayer or hymn).
Defn: A procedure to achieve evacuation of the bowel by the injection of fluid into the rectum.