### Clue: Firm sketch put up for Jessie and company care (6)
### Answer: COWARD 
 ### Explanation: Definition: Jessie
 1st: CO(abbrev. for "company"/a commercial firm) + **reversal of**(… put up, in a down clue) DRAW(to sketch); OR 2nd: CO(abbrev. for "company" + WARD(the state of being in the care of a guardian).
I can't see the significance, if any, to the double wordplay (and to the definition being in the middle of the clue).
Answer: ~~Jessie in Toy Story was claustrophobic, but was otherwise adventurous, feisty, energetic, etc.~~  Refer comments below.