### Clue: Oxford Uni fashion a wing that's isolated (3,2,1,4)
### Answer: OUT ON A LIMB 
 ### Explanation: OU(*Oxford Uni*versity) TON(*fashion*) A LIMB(*a wing*, as much a limb to a bird as an arm or a leg is to a mammal).  Defn:  The common meaning is "to be in a vulnerable, dangerous, compromising situation", but I guess it could also extend to "to be all by oneself",*isolated*.  From the literal sense that if you're out on a limb,branch, no-one can join you, lest the branch breaks.