### Clue: Nullify threat from doctor as I'm about to perform an amputation? (6)
### Answer: DISARM 
 ### Explanation: Definition: Nullify threat
 Double wordplay: 1st: **Anagram of**(… about) [ DR(abbrev. for "doctor") + AS I'M]; and 2nd: DIS-ARM(whimsically, to take away;amputate an arm from one's body).