### Clue: Disease causing swelling of beer belly containing penultimate part of gallon (4)
### Answer: GOUT 
 ### Explanation: Definition: Disease causing swelling
  GUT(beer belly,the enlarged paunch from habitual beer drinking) **containing**(containing) O(last but one letter,penultimate part of "gallon"). 
Answer: A disease causing pain and swelling, but not of your belly.