### Clue: Importance of parasites coming back, in a manner of speaking (11)
### Answer: DISTINCTION 
 ### Explanation: Definition: Importance
 **Reversal of**(… coming back) NITS(the young form of lice and other parasitic insects) **contained in**(in) DICTION(a manner of speaking/the style of enunciation in speech).
Defn: Having great significance, setting something or someone apart from others.