### Clue: Lassie from Sirius? (3,4)
### Answer: DOG STAR 
 ### Explanation: Definition: Lassie,Sirius
  Double defn: (or cryptic defn. if you prefer) 1st: The canine character which first appeared in a short story, "Lassie Come Home", then a novel, then movies, and then went on to a long-running TV series.  The stars in the role were the original male dog in the movies and his male descendants – why not, if humans can do it, so can their best friends; and 2nd: Sirius, the brightest star in the night sky (and actually a binary star system), is known as the "dog star" because of its prominence in its constellation, Canis Major.