### Clue: Twerp! I am one behind schedule for pick up (10)
### Answer: ASSIMILATE 
 ### Explanation: Definition: pick up
 ASS(a fool;in slang, a "twerp") + I'M(contraction for "I am") + I(Roman numeral for "one") + LATE(behind schedule).
Defn: To pick up;to, say, learn and understand thoroughly.