AmelieSchreiber
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Update README.md
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README.md
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@@ -30,7 +30,7 @@ of simple models and techniques. Moreover, since most proteins still do not have
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have a model that can predict binding residues from sequence alone. We also hope that this project will be helpful in this regard.
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It has been shown that pLMs like ESM-2 contain structural information in the attention maps that recapitulate the contact maps of proteins,
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and that single sequence masked language models like ESMFold can be used in atomically accurate predictions of folds, even outperforming
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AlphaFold2
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in a 1-to-1 fashion provides competative and possibly even SOTA performance, although our comparison to the SOTA models is not as fair and
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comprehensive as it could be (see [this report for more details](https://api.wandb.ai/links/amelie-schreiber-math/0asqd3hs)).
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have a model that can predict binding residues from sequence alone. We also hope that this project will be helpful in this regard.
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It has been shown that pLMs like ESM-2 contain structural information in the attention maps that recapitulate the contact maps of proteins,
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and that single sequence masked language models like ESMFold can be used in atomically accurate predictions of folds, even outperforming
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+
AlphaFold2. In our approach we show a positive correlation between scaling the model size and data
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in a 1-to-1 fashion provides competative and possibly even SOTA performance, although our comparison to the SOTA models is not as fair and
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35 |
comprehensive as it could be (see [this report for more details](https://api.wandb.ai/links/amelie-schreiber-math/0asqd3hs)).
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