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792 Conditions for Further Study Functional Consequences of Persistent Complex Bereavement Disorder Persistent complex bereavement di sorder is associated with deficits in work and social func- tioning and with harmful health behaviors, such as increased tobacco and alcohol use. It is also associated with marked increases in risks for serious medical conditions, including cardiac dis- ease, hypertension, cancer, immunological deficiency, and reduced quality of life. Differential Diagnosis Normal grief. Persistent complex bereavement diso rder is distinguished from normal grief by the presence of severe grief reactions that persist at least 12 months (or 6 months in children) after the death of the bereaved. It is only when severe levels of grief response per- sist at least 12 months following the death an d interfere with the in dividual’s capacity to function that persisten t complex bereavement disorder is diagnosed. Depressive disorders. Persistent complex bereavement disorder, major depressive dis- order, and persistent depressive disorder (dysthymia) share sadness, crying, and suicidal thinking. Whereas major depressi ve disorder and persistent de pressive disorder can share depressed mood with persistent complex bereavement disorder, the latter is characterized by a focus on the loss. Posttraumatic stress disorder. Individuals who experience bereavement as a result of trau- matic death may develop both posttraumatic stre ss disorder (PTSD) and persistent complex bereavement disorder. Both conditions ca n involve intrusive th oughts and avoidance. Whereas intrusions in PTSD revolve around the traumatic event, intrusive memories in per- sistent complex bereavement diso rder focus on thoughts about many aspects of the relation- ship with the deceased, including positive asp ects of the relationship and distress over the
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ship with the deceased, including positive asp ects of the relationship and distress over the separation. In individuals with the traumatic be reavement specifier of persistent complex be- reavement disorder, the distressin g thoughts or feelings may be more overtly related to the manner of death, with distressing fantasies of what happened. Both persistent complex be- reavement disorder and PTSD can involve avoi dance of reminders of distressing events. Whereas avoidance in PTSD is characterized by consistent avoidance of internal and external reminders of the traumatic experience, in persistent complex bereavement disorder, there is also a preoccupation with the loss and yearning for the deceased, which is absent in PTSD. Separation anxiety disorder. Separation anxiety disorder is characterized by anxiety about separation from current attachment figures, whereas persistent complex bereavement disorder involves distress about separation from a deceased individual. Comorbidity The most common comorbid disorders with pe rsistent complex bere avement disorder are major depressive disorder, PT SD, and substance use disorders. PTSD is more frequently comorbid with persistent complex bereavement disorder when the deat h occurred in trau- matic or violent circumstances. Caffeine Use Disorder Proposed Criteria A problematic pattern of caffeine use leading to clinically significant impairment or distress, as manifested by at least the first three of the following criteria occurring within a 12-month period: 1. A persistent desire or unsuccessful efforts to cut down or control caffeine use. 2. Continued caffeine use despite knowledge of having a persistent or recurrent physical or psychological problem that is likely to have been caused or exacerbated by caffeine.
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Conditions for Further Study 793 3. Withdrawal, as manifested by either of the following: a. The characteristic withdrawal syndrome for caffeine. b. Caffeine (or a closely related) substance is taken to relieve or avoid withdrawal symptoms. 4. Caffeine is often taken in larger amounts or over a longer period than was intended. 5. Recurrent caffeine use resulting in a failure to fulfill major role obligations at work, school, or home (e.g., repeated tardiness or absences from work or school related to caffeine use or withdrawal). 6. Continued caffeine use despite having persist ent or recurrent social or interpersonal problems caused or exacerbated by the effects of caffeine (e.g., arguments with spouse about consequences of use, medical problems, cost). 7. Tolerance, as defined by either of the following: a. A need for markedly increased amounts of caffeine to achieve desired effect. b. Markedly diminished effect with continued use of the same amount of caffeine. 8. A great deal of time is spent in activities necessary to obtain caffeine, use caffeine, or recover from its effects. 9. Craving or a strong desire or urge to use caffeine. A diagnosis of substance dependence due to caffeine is recognized by the World Health Organization in ICD-10. Since the publication of DSM-IV in 1994, considerable research on caffeine dependence has been published, an d several recent reviews provide a current analysis of this literature. There is now sufficie nt evidence to warran t inclusion of caffeine use disorder as a research diagnosis in DSM-5 to encourage additional research. The work- ing diagnostic algorithm propos ed for the study of caffeine use disorder differs from that of the other substance use disorders, reflecting the need to identify only cases that have
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of the other substance use disorders, reflecting the need to identify only cases that have sufficient clinical importance to warrant the la beling of a mental disorder. A key goal of in- cluding caffeine use disorder in this section of DSM-5 is to stimulate research that will determine the reliability, validity, and preval ence of caffeine use disorder based on the proposed diagnostic schema, with particular attention to the association of the diagnosis with functional impairments as part of validity testing. The proposed criteria for caff eine use disorder reflect the need for a diagnostic thresh- old higher than that used for the other subs tance use disorders. Such a threshold is in- tended to prevent overdiagnosis of caffeine us e disorder due to the high rate of habitual nonproblematic daily caffeine use in the general population. Diagnostic Features Caffeine use disorder is characterized by the continued use of caffeine and failure to con- trol use despite negative physical and/or psyc hological consequences. In a survey of the general population, 14% of caffeine users met the criterion of use despite harm, with most reporting that a physician or counselor had advised them to stop or reduce caffeine use within the last year. Medical and psychological problems attributed to caffeine included heart, stomach, and urinary problems, and co mplaints of anxiety, depression, insomnia, irritability, and difficulty thinking. In the sam e survey, 45% of caffei ne users reported de- sire or unsuccessful efforts to control caffeine use, 18% repo rted withdrawal, 8% reported tolerance, 28% used more than intended, and 50% reported spending a great deal of time using caffeine. In addition, 19% reported a strong desire for caffeine that they could not re-
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sist, and less than 1% reported that caffein e had interfered with social activities. Among those seeking treatment for quitting problematic caffeine use, 88% reported having made prior serious attempts to modify caffeine use, and 43% reported having been advised by a medical professional to reduce or eliminate caffeine. Ninety-three percent endorsed signs and symptoms meeting DSM-IV criteria for caffeine dependence, with the
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794 Conditions for Further Study most commonly endorsed criteria being withdr awal (96%), persistent desire or unsuccess- ful efforts to control use (89%), and use de spite knowledge of physical or psychological problems caused by caffeine (87%). The most common reasons for wanting to modify caf- feine use were health-related (59%) and a desire to not be dependent on caffeine (35%). The DSM-5 discussion of ca ffeine withdrawal in the Section II chapter “Substance- Related and Addictive Disorders” provides info rmation on the features of the withdrawal criterion. It is well documented that habitual caffeine users can experience a well-defined withdrawal syndrome upon ac ute abstinence from caffeine, and many caffeine-dependent individuals report continued use of caffeine to avoid experiencing withdrawal symptoms. Prevalence The prevalence of caffeine use di sorder in the general population is unclear. Based on all seven generic DSM-IV-TR criteria for dependence, 30% of current caffeine users may have met DSM-IV criteria for a diagnosis of caffei ne dependence, with endorsement of three or more dependence criteria, during the past year . When only four of the seven criteria (the three primary criteria proposed above plus to lerance) are used, the prevalence appears to drop to 9%. Thus, the expected prevalence of caffeine use disorder among regular caffeine users is likely less than 9%. Given that approximately 75%–80% of the general population uses caffeine regularly, the estimated preval ence would be less than 7%. Among regular caffeine drinkers at higher risk for caffeine use problems (e.g., high school and college stu- dents, individuals in drug treatment, and indi viduals at pain clinics who have recent his- tories of alcohol or illicit drug misuse), ap proximately 20% may have a pattern of use that
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meets all three of the proposed criteria in Criterion A. Development and Course Individuals whose patter n of use meets criteria for a ca ffeine use disorder have shown a wide range of daily caffeine intake and have been consumer s of various types of caffein- ated products (e.g., coffee, soft drinks, tea) and medications. A diagnosis of caffeine use disorder has been shown to prospectively pred ict a greater incidence of caffeine reinforce- ment and more severe withdrawal. There has been no longitudinal or cross-sect ional lifespan research on caffeine use dis- order. Caffeine use disorder has been identi fied in both adolescents and adults. Rates of caffeine consumption and overa ll level of caffeine consumption tend to increase with age until the early to mid-30s and then level off. Age-related factors for caffeine use disorder are unknown, although concern is growing related to excessive caffeine consumption among adolescents and young adults through use of caffeinated energy drinks. Risk and Prognostic Factors Genetic and physiological. Heritabilities of heavy caffeine use, caffeine tolerance, and caffeine withdrawal range from 35% to 77%. For caffeine use, alcohol use, and cigarette smoking, a common genetic factor (polysubst ance use) underlies the use of these three substances, with 28%–41% of the heritable e ffects of caffeine use (or heavy use) shared with alcohol and smoking. Caffeine and toba cco use disorders are associated and substan- tially influenced by genetic factors unique to these licit drugs. The magnitude of heritabil- ity for caffeine use disorder ma rkers appears to be similar to that for alcohol and tobacco use disorder markers. Functional Consequences of Caffeine Use Disorder
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use disorder markers. Functional Consequences of Caffeine Use Disorder Caffeine use disorder may predict greater use of caffeine during pregnancy. Caffeine with- drawal, a key feature of caffeine use disorder, has been shown to produce functional im-
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Conditions for Further Study 795 pairment in normal daily activities. Caffeine intoxication may include symptoms of nausea and vomiting, as well as impairment of normal activities. Significant disruptions in normal daily activities may occur during caffeine abstinence. Differential Diagnosis Nonproblematic use of caffeine. The distinction between nonproblematic use of caf- feine and caffeine use disorder can be difficul t to make because social, behavioral, or psy- chological problems may be difficult to attribut e to the substance, espe cially in the context of use of other substances. Regular, heavy caffeine use that can result in tolerance and with- drawal is relatively common, which by itself sh ould not be sufficient for making a diagnosis. Other stimulant use disorder. Problems related to use of other stimulant medications or substances may approximate the fe atures of caffeine use disorder. Anxiety disorders. Chronic heavy caffeine use may mimi c generalized anxiety disorder, and acute caffeine cons umption may produce and mimic panic attacks. Comorbidity There may be comorbidity between caffeine use disorder and daily cigarette smoking, a family or personal history of alcohol use diso rder. Features of caffeine use disorder (e.g., tolerance, caffeine withdrawal) may be positive ly associated with several diagnoses: ma- jor depression, generali zed anxiety disorder, panic disorder, adult antisocial personality disorder, and alcohol, cannab is, and cocaine use disorders. Internet Gaming Disorder Proposed Criteria Persistent and recurrent use of the Internet to engage in games, often with other players, leading to clinically significant impairment or distress as indicated by five (or more) of the following in a 12-month period: 1. Preoccupation with Internet games. (The individual thinks about previous gaming
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1. Preoccupation with Internet games. (The individual thinks about previous gaming activity or anticipates playing the next game; Internet gaming becomes the dominant activity in daily life). Note: This disorder is distinct from Internet gambling, which is included under gam- bling disorder. 2. Withdrawal symptoms when Internet gami ng is taken away. (These symptoms are typ- ically described as irritability, anxiety, or sadness, but there are no physical signs of pharmacological withdrawal.) 3. Tolerance—the need to spend increasing amounts of time engaged in Internet games. 4. Unsuccessful attempts to control the participation in Internet games. 5. Loss of interests in previous hobbies and entertainment as a result of, and with the ex- ception of, Internet games. 6. Continued excessive use of Internet games despite knowledge of psychosocial problems. 7. Has deceived family members, therapists, or others regarding the amount of Internet gaming. 8. Use of Internet games to escape or relieve a negative mood (e.g., feelings of helpless- ness, guilt, anxiety). 9. Has jeopardized or lost a significant relationship, job, or educational or career oppor- tunity because of participation in Internet games.
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796 Conditions for Further Study Note: Only nongambling Internet games are included in this disorder. Use of the Internet for required activities in a business or profe ssion is not included; nor is the disorder intend- ed to include other recreational or social Internet use. Similarly, sexual Internet sites are excluded. Specify current severity: Internet gaming disorder can be mild, moderate, or severe depending on the degree of disruption of normal activities. Individuals with less severe Internet gaming disorder may exhibit fewer symptoms and less disruption of their lives. Those with severe Inter- net gaming disorder will have more hours spent on the computer and more severe loss of relationships or career or school opportunities. Subtypes There are no well-researched subtypes for Inte rnet gaming disorder to date. Internet gam- ing disorder most often involves specific Inte rnet games, but it co uld involve non-Internet computerized games as well, although these have been less researched. It is likely that pre- ferred games will vary over time as new games are developed and popularized, and it is unclear if behaviors and consequence associat ed with Internet gaming disorder vary by game type. Diagnostic Features Gambling disorder is currently the only non-substance-related disorder proposed for in- clusion with DSM-5 substance-related and addi ctive disorders. However, there are other behavioral disorders that show some similari ties to substance use disorders and gambling disorder for which the word addiction is commonly used in nonmedical settings, and the one condition with a considerab le literature is the compulsive playing of Internet games. Internet gaming has been reportedly define d as an “addiction” by the Chinese govern- ment, and a treatment system has been set up. Reports of treatment of this condition have
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ment, and a treatment system has been set up. Reports of treatment of this condition have appeared in medical journals, mostly from A sian countries and some in the United States. The DSM-5 work group reviewed more than 240 articles and found some behavioral similarities of Internet gaming to gambling disorder and to substance use disorders. The literature suffers, howeve r, from lack of a standard defini tion from which to derive prev- alence data. An understanding of the natural histories of cases, with or without treatment, is also missing. The literature does describe many underlying similarities to substance ad- dictions, including aspects of tolerance, withdr awal, repeated unsuccessful attempts to cut back or quit, and impairment in normal func tioning. Further, the seemingly high preva- lence rates, both in Asian countries and, to a lesser extent, in the West, justified inclusion of this disorder in Section III of DSM-5. Internet gaming disorder has significant public health importance, and additional re- search may eventually lead to evidence that Internet gaming disorder (also commonly re- ferred to as Internet use disorder, Internet addiction, or gaming addiction ) has merit as an independent disorder. As with gambling disord er, there should be epidemiological stud- ies to determine prevalence, c linical course, possible geneti c influence, and potential bio- logical factors based on, for example, brain imaging data. Internet gaming disorder is a pattern of exce ssive and prolonged Inte rnet gaming that re- sults in a cluster of cognitive and behavioral symptoms, including progressive loss of control over gaming, tolerance, and withdrawal sy mptoms, analogous to the symptoms of sub- stance use disorders. As with substance-related disorders, individuals with Internet gaming
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stance use disorders. As with substance-related disorders, individuals with Internet gaming disorder continue to sit at a computer and en gage in gaming activi ties despite neglect of other activities. They typically de vote 8–10 hours or more per day to this activity and at least 30 hours per week. If they are prevented from using a computer and returning to the game, they become agitated and angry. They often go for long periods without food or sleep. Nor-
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Conditions for Further Study 797 mal obligations, such as school or work, or family obligati ons are neglected. This condition is separate from gambling disorder involving the Internet because mo ney is not at risk. The essential feature of Internet gaming di sorder is persistent an d recurrent participa- tion in computer gaming, ty pically group games, for many hours. These games involve competition between groups of players (often in different global regions, so that duration of play is encouraged by the time-zone inde pendence) participating in complex structured activities that include a significant aspect of social interactions during play. Team aspects appear to be a key motivation. Attempts to di rect the individual toward schoolwork or in- terpersonal activities are strongly resisted. Thus personal, family, or vocational pursuits are neglected. When individuals are asked, the major reasons given for using the com- puter are more likely to be “avoiding boredo m” rather than communicating or searching for information. The description of criteria rela ted to this condition is adapt ed from a study in China. Un- til the optimal criteria and threshold for di agnosis are determined empirically, conserva- tive definitions ought to be used, such that diagnoses are considered for endorsement of five or more of nine criteria. Associated Features Supporting Diagnosis No consistent personality types associated with Internet gaming disorder have been iden- tified. Some authors describe associated diagnoses, such as depressive disorders, atten- tion-deficit/hyperactivity disorder (ADHD) , or obsessive-compulsive disorder (OCD). Individuals with compulsive Internet gaming have demonstrated brain activation in spe- cific regions triggered by exposure to the Internet game but not limited to reward system structures Prevalence The prevalence of Internet gaming disorder is unclear because of the varying question-
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Prevalence The prevalence of Internet gaming disorder is unclear because of the varying question- naires, criteria and thresholds employed, but it seems to be highest in Asian countries and in male adolescents 12–20 years of age. There is an abundance of reports from Asian coun- tries, especially China and South Korea, bu t fewer from Europe and North America, from which prevalence estimates are highly variable . The point prevalence in adolescents (ages 15–19 years) in one Asian study using a threshold of five criteria was 8.4% for males and 4.5% for females. Risk and Prognostic Factors Environmental. Computer availability with Internet connection allows access to the types of games with which Internet gami ng disorder is most often associated. Genetic and physiological. Adolescent males seem to be at greatest risk of developing Internet gaming disorder, and it has been sp eculated that Asian environmental and/or ge- netic background is another risk factor, but this remains unclear. Functional Consequences of Internet Gaming Disorder Internet gaming disorder may lead to school failure, job loss, or marriage failure. The com- pulsive gaming behavior tends to crowd out normal social, scholastic, and family activities. Students may show declining grades and eventu ally failure in school. Family responsibil- ities may be neglected. Differential Diagnosis Excessive use of the Internet not involving playing of online games (e.g., excessive use of social media, such as Facebook; viewing porn ography online) is not considered analogous
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798 Conditions for Further Study to Internet gaming disorder, and future rese arch on other excessive uses of the Internet would need to follow similar guidelines as suggested herein. Excessive gambling online may qualify for a separate diagnosis of gambling disorder. Comorbidity Health may be neglected due to compulsive ga ming. Other diagnoses that may be associ- ated with Internet gaming disorder incl ude major depressive disorder, ADHD, and OCD. Neurobehavioral Disorder Associated With Prenatal Alcohol Exposure Proposed Criteria A. More than minimal exposure to alcohol during gestation, including prior to pregnancy recognition. Confirmation of gestational exposure to alcohol may be obtained from ma- ternal self-report of alcohol use in pregnancy, medical or other records, or clinical ob- servation. B. Impaired neurocognitive functioning as manifested by one or more of the following: 1. Impairment in global intellectual performance (i.e., IQ of 70 or below, or a standard score of 70 or below on a comprehensive developmental assessment). 2. Impairment in executive functioning (e.g., poor planning and organization; inflexi- bility; difficulty with behavioral inhibition). 3. Impairment in learning (e.g., lower academic achievement than expected for intel- lectual level; specific learning disability). 4. Memory impairment (e.g., problems remembering information learned recently; repeatedly making the same mistakes; difficulty remembering lengthy verbal in- structions). 5. Impairment in visual-spatial reasoning (e.g., disorganized or poorly planned draw- ings or constructions; problems differentiating left from right). C. Impaired self-regulation as manifested by one or more of the following: 1. Impairment in mood or behavioral regulation (e.g., mood lability; negative affect or irritability; frequent behavioral outbursts).
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irritability; frequent behavioral outbursts). 2. Attention deficit (e.g., difficulty shifting attention; difficulty sustaining mental effort). 3. Impairment in impulse control (e.g., difficulty waiting turn; difficulty complying with rules). D. Impairment in adaptive functioning as manifested by two or more of the following, one of which must be (1) or (2): 1. Communication deficit (e.g., delayed acquisition of language; difficulty understand- ing spoken language). 2. Impairment in social communication and interaction (e.g., overly friendly with strang- ers; difficulty reading social cues; difficulty understanding social consequences). 3. Impairment in daily living skills (e.g., delayed toileting, feeding, or bathing; difficulty managing daily schedule). 4. Impairment in motor skills (e.g., poor fine motor development; delayed attainment of gross motor milestones or ongoing deficits in gross motor function; deficits in co- ordination and balance). E. Onset of the disorder (symptoms in Criteria B, C, and D) occurs in childhood.
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Conditions for Further Study 799 F. The disturbance causes clinically significant distress or impairment in social, aca- demic, occupational, or other im portant areas of functioning. G. The disorder is not better explained by the direct physiological effects associated with postnatal use of a substance (e.g., a medication, alcohol or other drugs), a general medical condition (e.g., traumatic brain injury, delirium, dementia), another known te- ratogen (e.g., fetal hydantoin syndrome), a genetic condition (e.g., Williams syndrome, Down syndrome, Cornelia de Lange syndrome), or environmental neglect. Alcohol is a neurobehavioral te ratogen, and prenatal alcoho l exposure has teratogenic effects on central nervous system (CNS ) development and subsequent function. Neurobe- havioral disorder associated with prenatal alcohol exposure (ND-PAE) is a new clarifying term, intended to encompass the full range of de velopmental disabilities associated with expo- sure to alcohol in utero. The current diagnost ic guidelines allow ND-PAE to be diagnosed both in the absence and in the presence of th e physical effects of prenatal alcohol exposure (e.g., facial dysmorphology required for a diagnosis of fetal alcohol syndrome). Diagnostic Features The essential features of ND-PAE are the mani festation of impairment in neurocognitive, behavioral, and adaptive functioning associated with prenatal alcohol exposure. Impair- ment can be documented based on past diagnostic evaluation s (e.g., psychological or ed- ucational assessments) or medical records, reports by the in dividual or informants, and/ or observation by a clinician. A clinical diagnosis of fetal alcohol synd rome, including specific prenatal alcohol- related facial dysmorphology and growth retardation, can be used as evidence of signifi-
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related facial dysmorphology and growth retardation, can be used as evidence of signifi- cant levels of prenatal alcohol exposure. Although both animal and human studies have documented adverse effects of lower levels of drinking, identifying how much prenatal exposure is needed to sign ificantly impact neurodevelop mental outcome remains chal- lenging. Data suggest that a history of more than minimal gestationa l exposure (e.g., more than light drinking) prior to pregnancy reco gnition and/or following pregnancy recogni- tion may be required. Light drinking is defined as 1–13 drinks per month during preg- nancy with no more than 2 of these drinks co nsumed on any 1 drinking occasion. Identifying a minimal threshold of drinking during preg nancy will require consideration of a variety of factors known to affect exposure and/or interact to influence developmental outcomes, including stage of prenatal development, gestational smoking, maternal and fetal genet- ics, and maternal physical status (i.e., ag e, health, and certain obstetric problems). Symptoms of ND-PAE include marked impairment in global intellectual performance (IQ) or neurocognitive impair ments in any of the following areas: executive functioning, learning, memory, and/or visual-spatial reasoning. Impairments in self-regulation are pres- ent and may include impairment in mood or behavioral regulation, attention deficit, or impairment in impulse control. Finally, impa irments in adaptive functioning include com- munication deficits and impairment in soci al communication and interaction. Impairment in daily living (self-help) skills and impairment in motor skills may be present. As it may be difficult to obtain an accurate assessment of the neurocogni tive abilities of very young chil-
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dren, it is appropriate to defer a diagnosi s for children 3 years of age and younger. Associated Features Supporting Diagnosis Associated features vary depending on age, degree of alcohol exposure, and the individ- ual’s environment. An individual can be diag nosed with this disorder regardless of socio- economic or cultural background. However, ongoing parental alcohol/substance misuse, parental mental illness, exposure to domest ic or community violen ce, neglect or abuse,
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economic or cultural background. However, ongoing parental alcohol/substance misuse, parental mental illness, exposure to domest ic or community violen ce, neglect or abuse, disrupted caregiving relationships, multiple out-of-home placements, and lack of conti- nuity in medical or mental health care are often present.
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800 Conditions for Further Study Prevalence The prevalence rates of ND-PAE are unknown. However, estimated prevalence rates of clini- cal conditions associated with prenatal alco hol exposure are 2%–5% in the United States. Development and Course Among individuals with prenatal alcohol exposure, evidence of CNS dysfunction varies according to developmental stage. Although about one-half of young children prenatally exposed to alcohol show marked developmental delay in the first 3 years of life, other chil- dren affected by prenatal alcohol exposure may not exhibit signs of CNS dysfunction until they are preschool- or school-age. Additionally, impairments in higher order cognitive processes (i.e., executive functioning), which are often associated with prenatal alcohol ex- posure, may be more easily assessed in older children. When children reach school age, learning difficulties, impairme nt in executive function, and problems with integrative lan- guage functions usually emerge more clearly, and both social skills deficits and challeng- ing behavior may become more evident. In particular, as school and other requirements become more complex, greater deficits are no ted. Because of this, the school years repre- sent the ages at which a diagnosis of ND-PAE would be most likely. Suicide Risk Suicide is a high-risk outcome, with rates incr easing significantly in late adolescence and early adulthood. Functional Consequences of Neurobehavioral Disorder Associated With Prenatal Alcohol Exposure The CNS dysfunction seen in individuals with ND-PAE often leads to decrements in adap- tive behavior and to maladaptive behavior with lifelong consequences. Individuals affected by prenatal alcohol ex posure have a higher prevalence of disrupted school expe- riences, poor employme nt records, trouble with the law, confinement (legal or psychiat-
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ric), and dependent living conditions. Differential Diagnosis Disorders that are attributable to the physiolo gical effects associated with postnatal use of a substance, another medical condition, or environmental neglect. Other consid- erations include the physiological effects of po stnatal substance use, such as a medication, alcohol, or other substances; disorders due to another medical condition, such as traumatic brain injury or other neurocognitive disorder s (e.g., delirium, majo r neurocognitive dis- order [dementia]); or environmental neglect. Genetic and teratogenic conditions. Genetic conditions such as Williams syndrome, Down syndrome, or Cornelia de Lange syndro me and other teratogeni c conditions such as fetal hydantoin syndrome and maternal phen ylketonuria may have similar physical and behavioral characteristics. A careful review of prenatal exposure history is needed to clar- ify the teratogenic agent, and an evaluation by a clinical geneticist may be needed to dis- tinguish physical characteristics associated with these and other genetic conditions. Comorbidity Mental health problems have been identified in more than 90% of individuals with histo- ries of significant prenatal alcohol exposu re. The most common co-occurring diagnosis is attention-deficit/hyperactivity disorder, bu t research has shown that individuals with ND-PAE differ in neuropsychological charac teristics and in their responsiveness to phar-
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Conditions for Further Study 801 macological interventions. Ot her high- probability co-occurring disorders include oppo- sitional defiant disorder and co nduct disorder, but the appropriateness of these diagnoses should be weighed in the context of the sign ificant impairments in general intellectual and executive functioning that are often associa ted with prenatal al cohol exposure. Mood symptoms, including symptoms of bipolar diso rder and depressive disorders, have been described. History of prenatal alcohol exposure is associated with an increased risk for later tobacco, alcohol, and other substance use disorders. Suicidal Behavior Disorder Proposed Criteria A. Within the last 24 months, the individual has made a suicide attempt. Note: A suicide attempt is a self-initiated sequence of behaviors by an individual who, at the time of initiation, expected that the set of actions would lead to his or her own death. The “time of initiation” is the time when a behavior took place that involved ap- plying the method.) B. The act does not meet criteria for nonsuicidal self-injury—that is, it does not involve self-injury directed to the surface of the body undertaken to induce relief from a nega- tive feeling/cognitive state or to achieve a positive mood state. C. The diagnosis is not applied to suic idal ideation or to preparatory acts. D. The act was not initiated during a state of delirium or confusion. E. The act was not undertaken solely for a political or religious objective. Specify if: Current: Not more than 12 months since the last attempt. In early remission: 12–24 months since the last attempt. Specifiers Suicidal behavior is often categorized in term s of violence of the method. Generally, over-
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doses with legal or illegal substances are cons idered nonviolent in method, whereas jump- ing, gunshot wounds, and other methods are considered violent. Another dimension for classification is medical consequences of the behavior, with high-lethality attempts being defined as those requiring medical hospitalizat ion beyond a visit to an emergency depart- ment. An additional dimension considered incl udes the degree of planning versus impul- siveness of the attempt, a characteristic th at might have consequences for the medical outcome of a suicide attempt. If the suicidal behavior occurred 12–24 mo nths prior to evaluation, the condition is considered to be in early remission. Individua ls remain at higher risk for further suicide at- tempts and death in the 24 months after a suicide attempt, and the period 12–24 months af- ter the behavior took place is specified as “early remission.” Diagnostic Features The essential manifestation of suicidal be havior disorder is a suicide attempt. A suicide at- tempt is a behavior that the individual has undertak en with at least some intent to die. The behavior might or might not le ad to injury or serious medi cal consequences. Several fac- tors can influence the medical consequences of the suicide a ttempt, including poor plan- ning, lack of knowledge about the lethality of the method chosen, low intentionality or ambivalence, or chance intervention by others after the behavior has been initiated. These should not be considered in assigning the diagnosis.
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802 Conditions for Further Study Determining the degree of intent can be challenging. Individuals might not acknowl- edge intent, especially in situations where doin g so could result in hospitalization or cause distress to loved ones. Markers of risk includ e degree of planning, including selection of a time and place to minimize rescue or interrupt ion; the individual’s mental state at the time of the behavior, with acute agitation being especially concerning; recent discharge from inpatient care; or recent discon tinuation of a mood stabilizer such as lithium or an anti- psychotic such as clozapine in the case of schizophrenia. Examples of environmental “trig- gers” include recently learning of a potentia lly fatal medical diagnosis such as cancer, experiencing the sudden and unexpected loss of a close relative or partner, loss of employ- ment, or displacement from h ousing. Conversely, features su ch as talking to others about future events or preparedness to sign a contract for safety are less reliable indicators. In order for the criteria to be met, the indivi dual must have made at least one suicide at- tempt. Suicide attempts can incl ude behaviors in which, after initiating the suicide attempt, the individual changed his or her mind or so meone intervened. For example, an individual might intend to ingest a given amount of medication or pois on, but either stop or be stopped by another before ingesting the full amount. If the individual is dissuaded by another or changes his or her mind before initiating th e behavior, the diagnosis should not be made. The act must not meet criteria for nonsuicidal self-i njury—that is, it should not involve re- peated (at least five times within the past 12 months) self-injurious episodes undertaken to
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induce relief from a negative feeling/cognitive state or to achieve a positive mood state. The act should not have been initiated during a st ate of delirium or confusion. If the individual deliberately became intoxicated before initiating the behavior, to reduce anticipatory anxi- ety and to minimize interference with the inte nded behavior, the diagnosis should be made. Development and Course Suicidal behavior can occur at any time in the lifespan but is rarely seen in children under the age of 5. In prepubertal children, the behavi or will often consist of a behavior (e.g., sit- ting on a ledge) that a parent has forbidden because of the risk of accident. Approximately 25%–30% of persons who attempt suicide will go on to make more attempts.There is sig- nificant variability in terms of frequency, me thod, and lethality of attempts. However, this is not different from what is observed in other illnesses, such as major depressive disorder, in which frequency of episode, subtype of episode, and impa irment for a given episode can vary significantly. Culture-Related Diagnostic Issues Suicidal behavior varies in frequency and form across cultures. Cultural differences might be due to method availability (e.g., poisonin g with pesticides in developing countries; gunshot wounds in the southwestern United St ates) or the presence of culturally specific syndromes (e.g., ataques de nervios, which in some Latino group s might lead to behaviors that closely resemble suic ide attempts or might facilitate suicide attempts). Diagnostic Markers Laboratory abnormalities consequent to the suicidal attempt are of ten evident. Suicidal behavior that leads to blood loss can be a ccompanied by anemia, hypotension, or shock.
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Overdoses might lead to coma or obtundatio n and associated laboratory abnormalities such as electrolyte imbalances. Functional Consequences of Suicidal Behavior Disorder Medical conditions (e.g., lacerations or skel etal trauma, cardiopulm onary instability, in- halation of vomit and suffocation, hepatic fa ilure consequent to use of paracetamol) can occur as a consequence of suicidal behavior.
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Conditions for Further Study 803 Comorbidity Suicidal behavior is seen in th e context of a variety of mental disorders, most commonly bipo- lar disorder, major depressive disorder, schizo phrenia, schizoaffective disorder, anxiety dis- orders (in particular, panic disorders asso ciated with catastrophic content and PTSD flashbacks), substance use disorders (especially alcohol use disorders) , borderline personality disorder, antisocial personality disorder, eating disorders, and adjustment disorders. It is rarely manifested by individual s with no discernible pathology, unless it is undertaken be- cause of a painful medical condition with the in tention of drawing attention to martyrdom for political or religious reasons, or in partners in a suicide pact, both of which are excluded from this diagnosis, or when third-party informants wish to conceal the nature of the behavior. Nonsuicidal Self-Injury Proposed Criteria A. In the last year, the individual has, on 5 or more days, engaged in intentional self-inflicted damage to the surface of his or her body of a sort likely to induce bleeding, bruising, or pain (e.g., cutting, burning, stabbing, hitting, excessive rubbing), with the expectation that the injury will lead to only minor or moderate physi cal harm (i.e., there is no suicidal intent). Note: The absence of suicidal intent has either been stated by the individual or can be inferred by the individual’s repeated engagement in a behavior that the individual knows, or has learned, is not likely to result in death. B. The individual engages in the self-injurious behavior with one or more of the following expectations: 1. To obtain relief from a negative feeling or cognitive state. 2. To resolve an interpersonal difficulty.
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2. To resolve an interpersonal difficulty. 3. To induce a positive feeling state. Note: The desired relief or response is experienced during or shortly after the self- injury, and the individual may display patterns of behavior suggesting a dependence on repeatedly engaging in it. C. The intentional self-injury is associated with at least one of the following: 1. Interpersonal difficulties or negative feelings or thoughts, such as depression, anx- iety, tension, anger, generalized distress, or self-criticism, occurring in the period immediately prior to the self-injurious act. 2. Prior to engaging in the act, a period of preoccupation with the intended behavior that is difficult to control. 3. Thinking about self-injury that occurs frequently, even when it is not acted upon. D. The behavior is not socially sanctioned (e.g., body piercing, tattooing, part of a religious or cultural ritual) and is not restricted to picking a scab or nail biting. E. The behavior or its consequences cause clinically significant distress or interference in interpersonal, academic, or other important areas of functioning. F. The behavior does not occur exclusively during psychotic episodes, delirium, sub- stance intoxication, or substance withdrawal. In individuals with a neurodevelopmental disorder, the behavior is not part of a pattern of repetitive stereotypies. The behavior is not better explained by another mental disorder or medical condition (e.g., psychotic disorder, autism spectrum disorder, intellectual disability, Lesch-Nyhan syndrome, ste- reotypic movement disorder with self-injur y, trichotillomania [hair-pulling disorder], ex- coriation [skin-picking] disorder).
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804 Conditions for Further Study Diagnostic Features The essential feature of nonsuicidal self-injur y is that the individual repeatedly inflicts shallow, yet painful injuries to the surface of his or her body. Most commonly, the purpose is to reduce negative emotions, such as tensio n, anxiety, and self-reproach, and/or to re- solve an interpersonal difficulty. In some cases, the injury is conceived of as a deserved self-punishment. The individual will often report an immediate sensation of relief that oc- curs during the process. When the behavior o ccurs frequently, it mi ght be associated with a sense of urgency and craving, the resultant behavioral pattern resembling an addiction. The inflicted wounds can become deeper and more numerous. The injury is most often inflicted with a knif e, needle, razor, or other sharp object. Com- mon areas for injury include the frontal area of the thighs and the dorsal side of the forearm. A single session of injury might involve a se ries of superficial, parallel cuts—separated by 1 or 2 centimeters—on a visible or accessible location. The resulting cuts will often bleed and will eventually leave a characteristic pattern of scars. Other methods used include stabbing an area , most often the upper arm, with a needle or sharp, pointed knife; inflicti ng a superficial burn with a lit cigarette end; or burning the skin by repeated rubbing with an eraser. En gagement in nonsuicidal self-injury with mul- tiple methods is associated with more severe psychopathology, including engagement in suicide attempts. The great majority of individuals who engage in nonsuicidal self-injury do not seek clinical attention. It is not known if this re flects frequency of engagement in the disorder,
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because accurate reporting is seen as stigma tizing, or because the behaviors are experi- enced positively by the individual who engages in them, who is unmotivated to receive treatment. Young children might experiment wi th these behaviors but not experience re- lief. In such cases, youths often report that the procedure is painful or distressing and might then discontinue the practice. Development and Course Nonsuicidal self-injury most often starts in the early teen years and can continue for many years. Admission to hospital for nonsuicida l self-injury reaches a peak at 20–29 years of age and then declines. However, research that has examined age at hospitalization did not provide information on age at onset of the behavior, and prospective research is needed to outline the natural history of nonsuicidal self-injury and the factors that promote or in- hibit its course. Individuals often learn of th e behavior on the recommendation or observa- tion of another. Research has shown that wh en an individual who engages in nonsuicidal self-injury is admitted to an inpatient unit, other individuals may begin to engage in the behavior. Risk and Prognostic Factors Male and female prevalence rates of nonsuicida l self-injury are closer to each other than in suicidal behavior disorder, in which the female-to-male ratio is about 3:1 or 4:1. Two theories of psychopathology—based on functional behavioral analyses—have been proposed: In the first, based on learning theo ry, either positive or negative reinforcement sustains the behavior. Positive reinforcement might result fr om punishing oneself in a way that the individual feels is de served, with the behavior induci ng a pleasant and relaxed state
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that the individual feels is de served, with the behavior induci ng a pleasant and relaxed state or generating attention and help from a signific ant other, or as an expression of anger. Neg- ative reinforcement results from affect regula tion and the reduction of unpleasant emotions or avoiding distressing thoughts, including th inking about suicide. In the second theory, nonsuicidal self-injury is thought to be a form of self-punishment, in which self-punitive ac- tions are engaged in to make up for acts that caused distress or harm to others.
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Conditions for Further Study 805 Functional Consequences of Nonsuicidal Self-Injury The act of cutting might be performed with shared implements, raising the possibility of blood-borne disease transmission. Differential Diagnosis Borderline personality disorder. As indicated, nonsuicidal se lf-injury has long been re- garded as a “symptom” of borderline pers onality disorder, even though comprehensive clinical evaluations have found that most individuals with nonsuicidal self-injury have symptoms that also meet criteria for other di agnoses, with eating disorders and substance use disorders being especially common. Histor ically, nonsuicidal self-injury was regarded as pathognomonic of borderline personality d isorder. Both conditions are associated with several other diagnoses. Although frequently associated, borderline personality disorder is not invariably found in individuals with no nsuicidal self-injury. The two conditions dif- fer in several ways. Individuals with borderline personality disorder often manifest dis- turbed aggressive and hostile behaviors, whereas nonsuicidal self-injury is more often associated with phases of closeness, collaborati ve behaviors, and positive relationships. At a more fundamental level, there are difference s in the involvement of different neurotrans- mitter systems, but these will not be apparent on clinical examination. Suicidal behavior disorder. The differentiation between nonsuicidal self-injury and sui- cidal behavior disorder is base d either on the stated goal of the behavior being a wish to die (suicidal behavior disorder) or, in nonsuicidal self-injury, to experience relief as de- scribed in the criteria. Depending on the ci rcumstances, individuals may provide reports of convenience, and several studies report high rates of false intent declaration. Individu-
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of convenience, and several studies report high rates of false intent declaration. Individu- als with a history of frequent nonsuicidal se lf-injury episodes have learned that a session of cutting, while painful, is, in the short-term, largely benign. Be cause individuals with nonsuicidal self-injury can and do attempt and commit suicide, it is important to check past history of suicidal behavior and to ob tain information from a third party concerning any recent change in stress exposure and mo od. Likelihood of suicide intent has been as- sociated with the use of multiple previous methods of self-harm. In a follow-up study of cases of “self-harm” in males treated at one of several multiple emergency centers in the United Kingdom, in dividuals with nonsuicidal self-injury were significantly more likely to commit suicide th an other teenage individuals drawn from the same cohort. Studies that have examined the relationship be tween nonsuicidal self-injury and suicidal behavior disorder are limited by being retrospe ctive and failing to obtain ver- ified accounts of the method used during pr evious “attempts.” A significant proportion of those who engage in nonsuicidal self-injury have responded positively when asked if they have ever engaged in self-cutti ng (or their preferred means of self-injury) with an intention to die. It is reasonable to co nclude that nonsuicidal self-injury, while not presenting a high risk for suicide when first manifested, is an especially dangerous form of self-injurious behavior. This conclusion is also supported by a mult isite study of depressed adolescents who had previously failed to respond to antidepressant medi cation, which noted th at those with pre-
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vious nonsuicidal self-inj ury did not respond to cognitive-behavioral therapy, and by a study that found that nonsuicida l self-injury is a predicto r of substance use/misuse. Trichotillomania (hair-pulling disorder). Trichotillomania is an injurious behavior con- fined to pulling out one’s own hair, most commonly from the sc alp, eyebrows, or eyelashes. The behavior occurs in “sessions” that can last fo r hours. It is most likely to occur during a period of relaxation or distraction.
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806 Conditions for Further Study Stereotypic self-injury. Stereotypic self-injury, which can include head banging, self- biting, or self-hitting, is usually associated with intense concentration or under conditions of low external stimulation and might be associated with developmental delay. Excoriation (skin-picking) disorder. Excoriation disorder occurs mainly in females and is usually directed to picking at an area of th e skin that the individual feels is unsightly or a blemish, usually on the face or the scalp. As in nonsuicidal self-injury, the picking is often preceded by an urge and is experienced as pleasurable, even thoug h the individual real- izes that he or she is harming himself or hersel f. It is not associated with the use of any im- plement.
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APPENDIX Highlights of Changes From DSM-IV to DSM-5 . . . . . . . . . . . . . . . . . . .809 Glossary of Technical Terms . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .817 Glossary of Cultural Concepts of Distress . . . . . . . . . . . . . . . . . . . . . . .833 Alphabetical Listing of DSM-5 Diagnoses and Codes (ICD-9-CM and ICD-10-CM) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .839 Numerical Listing of DSM-5 Diagnoses and Codes (ICD-9-CM) . . . . . .863 Numerical Listing of DSM-5 Diagnoses and Codes (ICD-10-CM) . . . . .877 DSM-5 Advisors and Other Contributors. . . . . . . . . . . . . . . . . . . . . . . . .897
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809Highlights of Changes From DSM-IV to DSM-5 Changes made to DSM-5 diagnostic criteria and text s are outlined in this chapter in the same order in which they appear in the DSM-5 classification. This abbreviated descrip- tion is intended to orient readers to only the most significant changes in each disorder cate- gory. An expanded description of nearly all changes (e.g., except minor text or wording changes needed for clarity) is available online (www.psychiatry.org/ds m5). It should also be noted that Section I contains a description of changes pertaining to the chapter organization in DSM-5, the multiaxial sy stem, and the introduction of dimensional assessments. Neurodevelopmental Disorders The term mental retardation was used in DSM-IV. However, intellectual disability (intel- lectual developmental disorder) is the term that has come into common use over the past two decades among medical, ed ucational, and other professi onals, and by the lay public and advocacy groups. Diagnostic criteria em phasize the need for an assessment of both cognitive capacity (IQ) and adaptive functionin g. Severity is determined by adaptive func- tioning rather than IQ score. The communication disorders, which are newly named from DSM-IV phonological dis- order and stuttering, respectively, include language disorder (which combines the previous expressive and mixed receptive-ex pressive language disorders), speech sound disorder (pre- viously phonological disorder), and childhood-onset fluency disorder (previously stutter- ing). Also included is social (pragmatic) communication disorder, a new condition involving persistent difficulties in the social us es of verbal and nonverbal communication. Autism spectrum disorder is a new DSM-5 disorder encompassing the previous DSM-
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Autism spectrum disorder is a new DSM-5 disorder encompassing the previous DSM- IV autistic disorder (autism), Asperger’s disorder, childhood disi ntegrative disorder, Rett’s disorder, and pervasive developmental di sorder not otherwise specified. It is char- acterized by deficits in two core domains: 1) deficits in social communication and social in- teraction and 2) restricted repetitive patterns of behavior, interests, and activities. Several changes have been made to the diagnostic criteria for attention-deficit/hyperactiv- ity disorder (ADHD). Examples have been added to the criterion items to facilitate application across the life span; the age at onset descri ption has been changed (from “some hyperactive- impulsive or inattentive symptoms that caused impairment were present before age 7 years” to “Several inattentive or hy peractive-impulsive symptoms we re present prior to age 12”); subtypes have been replaced with presentation specifiers that map directly to the prior sub- types; a comorbid diagnosis with autism spec trum disorder is now allowed; and a symptom threshold change has been made for adults, to reflect the substantial evidence of clinically sig- nificant ADHD impairment, with the cutoff for ADHD of five symptoms, instead of six re- quired for younger persons, both for inatte ntion and for hyperactivity and impulsivity. Specific learning disorder combines the DSM-IV diagnose s of reading disorder, math- ematics disorder, disorder of written expression, and lear ning disorder not otherwise specified. Learning deficits in the areas of reading, written expr ession, and mathematics are coded as separate specifiers. Acknowledgment is made in the text that specific types of reading deficits are described internationally in various ways as dyslexia and specific types
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reading deficits are described internationally in various ways as dyslexia and specific types of mathematics deficits as dyscalculia.
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810 Highlights of Changes From DSM-IV to DSM-5 The following motor disorders are included in DSM-5: deve lopmental coordination disor- der, stereotypic movement disorder, Tourette’s disorder, persistent (chronic) motor or vocal tic disorder, provisional tic disorder, other spec ified tic disorder, and un specified tic disorder. The tic criteria have been standardized across all of these disorders in this chapter. Schizophrenia Spectrum and Other Psychotic Disorders Two changes were made to Criterion A for schizophrenia: 1) the elimination of the special at- tribution of bizarre delusions and Schneiderian fi rst-rank auditory hallucinations (e.g., two or more voices conversing), leadin g to the requirement of at least two Criterion A symptoms for any diagnosis of schizophrenia, and 2) the addition of the requirement that at least one of the Criterion A symptoms must be delusions, hallu cinations, or disorganized speech. The DSM-IV subtypes of schizophrenia were eliminated due to their limited diagnostic stability, low reli- ability, and poor validity. Instead, a dimensional approach to rating severity for the core symp- toms of schizophrenia is includ ed in DSM-5 Section III to capt ure the important heterogeneity in symptom type and severity expressed across individual s with psychotic disorders. Schizoaffective disorder is reconceptualized as a longitudin al instead of a cross-sectional di- agnosis—more comparable to schizophrenia, bipolar disorder, and majo r depressive disorder, which are bridged by this condition—and requires that a major mood episode be present for a majority of the total disorder ’s duration after Criterion A has been met. Criterion A for delu- sional disorder no longer has the requirement that th e delusions must be nonbizarre; a spec-
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ifier is now included for bizarre type delusions to provide continuity with DSM-IV. Criteria for catatonia are described uniformly across DSM-5. Fu rthermore, catatonia may be diagnosed with a specifier (for depressive, bipolar, and psychotic disorders, incl uding schizophrenia), in the context of a known medical condition, or as an other specified diagnosis. Bipolar and Related Disorders Diagnostic criteria for bipolar disorders now include both changes in mood and changes in activity or energy. The DSM-IV diagnosis of bipolar I disorder, mixed episodes—requiring that the individual simultaneous ly meet full criteria for both mania and major depressive ep- isode—is replaced with a new specifier “with mixed features.” Particular conditions can now be diagnosed under other specified bipolar and related disorder, including categori- zation for individuals with a past history of a major depressive di sorder whose symptoms meet all criteria for hypomania except the duration criterion is not met (i.e., the episode lasts only 2 or 3 days instead of the required 4 cons ecutive days or more). A second condition con- stituting an other specified bipolar and related disorder variant is that too few symptoms of hypomania are present to meet criteria for the full bipolar II syndrome, although the dura- tion, at least 4 consecutive days, is sufficient. Finally, in both this chapter and in the chapter “Depressive Disorders,” an anxious distress specifier is delineated. Depressive Disorders To address concerns about potential overdiagno sis and overtreatment of bipolar disorder in children, a new diagnosis, disruptive mood dysregulation disorder, is included for children up to age 18 years who exhibit persistent irrita bility and frequent episodes of extreme behav-
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ioral dyscontrol. Premenstrual dysphoric disorder is now promoted from Appendix B, “Cri- teria Sets and Axes Provided for Further Study, ” in DSM-IV to the main body of DSM-5. What was referred to as dysthymia in DSM-IV now falls under the category of persistent depressive disorder, which includes both chronic major depre ssive disorder and the previous dysthymic
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was referred to as dysthymia in DSM-IV now falls under the category of persistent depressive disorder, which includes both chronic major depre ssive disorder and the previous dysthymic disorder. The coexistence within a major depressive episode of at least three manic symp- toms (insufficient to satisfy cr iteria for a manic episode) is no w acknowledged by the specifier
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Highlights of Changes From DSM-IV to DSM-5 811 “with mixed features.” In DSM-IV, there was an exclusion criterion for a major depressive ep- isode that was applied to depressive symptoms lasting less than 2 months following the death of a loved one (i.e., the bereavement exclusion). This exclusion is omitted in DSM-5 for several reasons, including the recognitio n that bereavement is a severe psychosocial stressor that can precipitate a major depressive episode in a vu lnerable individual, generally beginning soon after the loss, and can add an additional risk for suffering, feelings of worthlessness, suicidal ideation, poorer medical health, and worse interp ersonal and work functioning. It was critical to remove the implication that bereavement ty pically lasts only 2 months, when both physi- cians and grief counselors recognize that the duration is more commonly 1–2 years. A detailed footnote has replaced the more simplistic DSM- IV exclusion to aid clinicians in making the critical distinction between the symptoms characteristic of be reavement and those of a major depressive disorder. Finally, a new specifier to indicate the presence of mixed symptoms has been added across both the bipo lar and the depressive disorders. Anxiety Disorders The chapter on anxiety disorders no longer includes obsessive-compulsive disorder (which is in the new chapter “Obsessive-Compulsiv e and Related Disorders”) or posttraumatic stress disorder (PTSD) and acut e stress disorder (which are in the new chapter “Trauma- and Stressor-Related Disorders”). Changes in criteria for specific phobia and social anxiety disorder (social phobia) include deletion of the requirement that individuals over age 18 years recognize that their anxiet y is excessive or unreasonable . Instead, the anxiety must be
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years recognize that their anxiet y is excessive or unreasonable . Instead, the anxiety must be out of proportion to the actual danger or threat in the situation, after cultural contextual fac- tors are taken into account. In addition, the 6-month duration is now extended to all ages. Panic attacks can now be listed as a specifier that is applicable to all DSM-5 disorders. Panic disorder and agoraphobia are unlinked in DSM-5. Thus, the former DSM-IV diagnoses of panic disorder with agoraphobia, panic disorder without agoraphobia, and agoraphobia without history of panic disorder are now replaced by two diagnoses, panic disorder and ag- oraphobia, each with separate crit eria. The “generalized” specifier for social anxiety disor- der has been deleted and replaced with a “performance only” specifier. Separation anxiety disorder and selective mutism are now classified as anxiety di sorders. The wording of the criteria is modified to more adequately repres ent the expression of se paration anxiety symp- toms in adulthood. Also, in contrast to DSM-IV, the diagnostic criteria no longer specify that onset must be before age 18 years, and a duration statement—“typically lasting for 6 months or more”—has been added for adults to minimize overdia gnosis of transient fears. Obsessive-Compulsive and Related Disorders The chapter “Obsessive-Compulsive and Related Disorders” is new in DSM-5. New disor- ders include hoarding disorder, excoriation (skin-pi cking) disorder, substance/medica- tion-induced obsessive-compulsive and related disorder, and obsessive-compulsive and related disorder due to another medical condition. The DSM-IV diagnosis of trichotillo-
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mania is now termed trichotillomania (hair-pulling disorder) and has been moved from a DSM-IV classification of impulse-control di sorders not elsewhere classified to obsessive- compulsive and related disorders in DSM-5. The DSM-IV “with poor insight” specifier for obsessive-compulsive disorder has been refined to allow a distinction between individuals with good or fair insight, poor insight, and “absent insight/delusional” obsessive-compul- sive disorder beliefs (i.e., comp lete conviction that obsessive-compulsive disorder beliefs
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with good or fair insight, poor insight, and “absent insight/delusional” obsessive-compul- sive disorder beliefs (i.e., comp lete conviction that obsessive-compulsive disorder beliefs are true). Analogous “insight” specifiers have been included for body dysmorphic disorder and hoarding disorder. A “tic-related” specifier for obsessive-compuls ive disorder has also been added, because presence of a comorbid tic disorder may have important clinical im- plications. A “muscle dy smorphia” specifier for body dysmorphic disorder is added to re- flect a growing literature on the diagnostic validity and clinical utility of making this
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812 Highlights of Changes From DSM-IV to DSM-5 distinction in individuals with body dysmorphic disorder. The delusional variant of body dysmorphic disorder (which identifies individu als who are completely convinced that their perceived defects or flaws are truly abnormal ap pearing) is no longer coded as both delu- sional disorder, somatic type, and body dysmorph ic disorder; in DSM-5, this presentation is designated only as body dysmorphic disorder with the absent insight/delusional specifier. Individuals can also be diagnosed with other specified obsessive-compulsive and related disorder, which can include conditions such as body-focused repetitive behavior disorder and obsessional jealousy, or unspecified obsessive-compulsive and related disorder. Trauma- and Stressor-Related Disorders For a diagnosis of acute stress disorder, qualifying traumatic events are now explicit as to whether they were experienced directly, witnessed, or experienced indirectly. Also, the DSM-IV Criterion A2 regarding the subjective reaction to th e traumatic event (e.g., expe- riencing “fear, helplessness, or horror”) has been eliminated. Adjustment disorders are reconceptualized as a heterogeneous array of stress-response syndromes that occur after exposure to a distressing (traum atic or nontraumatic) event, rather than as a residual cat- egory for individuals who exhibit clinically significant distress but whose symptoms do not meet criteria for a more d iscrete disorder (as in DSM-IV). DSM-5 criteria for PTSD differ significantly from the DS M-IV criteria. The stressor cri- terion (Criterion A) is more ex plicit with regard to events that qualify as “traumatic” ex- periences. Also, DSM-IV Criterion A2 (subje ctive reaction) has been eliminated. Whereas
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there were three major symptom clusters in DSM-IV—reexperiencing, avoidance/numb- ing, and arousal—there are no w four symptom clusters in DSM-5, because the avoidance/ numbing cluster is divided into two distinct clusters: avoidance and persistent negative al- terations in cognitions and mood. This latter category, which retains most of the DSM-IV numbing symptoms, also includes new or re conceptualized symptoms, such as persistent negative emotional states. The final cluster— alterations in arousal and reactivity—retains most of the DSM-IV arousal symptoms. It also includes irritable behavior or angry out- bursts and reckless or self-destructive beha vior. PTSD is now develo pmentally sensitive in that diagnostic thresholds have been lowe red for children and adolescents. Furthermore, separate criteria have been added for childre n age 6 years or younger with this disorder. The DSM-IV childhood diagno sis reactive attachment di sorder had two subtypes: emotionally withdrawn/inhibited and indiscri minately social/disinhibited. In DSM-5, these subtypes are defined as distinct disorders: reactive attachment disorder and disin- hibited social engagement disorder. Dissociative Disorders Major changes in dissociative disorders in DS M-5 include the following: 1) derealization is included in the name and symptom structure of what previously was called depersonali- zation disorder ( depersonalization/derealization disorder ); 2) dissociative fugue is now a specifier of dissociative amnesia rather than a separate diagnosis, and 3) the criteria for dissociative identity disorder have been changed to indicate that symptoms of disruption of identity may be reported as well as observed, and that gaps in the recall of events may
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of identity may be reported as well as observed, and that gaps in the recall of events may occur for everyday and not just traumatic ev ents. Also, experiences of pathological pos- session in some cultures are included in the description of identity disruption. Somatic Symptom and Related Disorders In DSM-5, somatoform disorders are now referred to as somatic symptom and related dis- orders. The DSM-5 classification reduces the number of these disorders and subcategories to avoid problematic overlap. Diagnoses of somatization disorder, hypochondriasis, pain dis-
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orders. The DSM-5 classification reduces the number of these disorders and subcategories to avoid problematic overlap. Diagnoses of somatization disorder, hypochondriasis, pain dis- order, and undifferentiated somatoform diso rder have been removed. Individuals previ-
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Highlights of Changes From DSM-IV to DSM-5 813 ously diagnosed with somatization disorder wi ll usually have sympto ms that meet DSM-5 criteria for somatic symptom disorder, but only if they have th e maladaptive thoughts, feel- ings, and behaviors that define the disorder, in addition to their somatic symptoms. Because the distinction between somati zation disorder and undifferen tiated somatoform disorder was arbitrary, they are merged in DSM-5 un der somatic symptom diso rder. Individuals pre- viously diagnosed with hypochondriasis who have high health anxiety but no somatic symp- toms would receive a DSM-5 diagnosis of illness anxiety disorder (unless their health anxiety was better explained by a primary anxiety disorder, su ch as generalized anxiety dis- order). Some individuals with chronic pain w ould be appropriately di agnosed as having so- matic symptom disorder, with predominant pain . For others, psychological factors affecting other medical conditions or an adjustment disorder would be more appropriate. Psychological factors affect ing other medical conditions is a new mental disorder in DSM-5, having formerly been listed in the DSM-IV chapter “Other Conditions That May Be a Focus of Clinical At tention.” This disorder and factitious disorder are placed among the somatic symptom and related disorders because somatic symptoms are predominant in both disorders, and both are most often en countered in medical settings. The variants of psychological factors affecting other medical conditions are removed in favor of the stem diagnosis. Criteria for conversion disorder (functional neurological symptom disorder) have been modified to emphasize the essent ial importance of the neurological examina- tion, and in recognition that relevant psychological factors may not be demonstrable at the time of diagnosis. Other spec ified somatic symptom disorder , other specified illness anx-
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time of diagnosis. Other spec ified somatic symptom disorder , other specified illness anx- iety disorder, and pseudocyesis ar e now the only exemplars of the other specified somatic symptom and related disorder classification. Feeding and Eating Disorders Because of the elimination of the DSM-IV-TR chapter “Disorders Us ually First Diagnosed During Infancy, Childhood, or Adolescence,” th is chapter describes several disorders found in the DSM-IV section “Feeding and Eating Disord ers of Infancy or Early Childhood,” such as pica and rumination disorder. The DSM-IV category feeding disorder of infancy or early childhood has been renamed avoidant/restrictive f ood intake disorder, and the criteria are significantly expanded. The core diagnostic criteria for anorexia nervosa are conceptually un- changed from DSM-IV with one exception: the requirement for amenorrhea is eliminated. As in DSM-IV, individuals with this disorder are requ ired by Criterion A to be at a significantly low body weight for their developmental stage. The wording of the criterion is changed for clarification, and guidan ce regarding how to judge whether an individual is at or below a sig- nificantly low weight is provided in the text. In DSM-5, Criterion B is expanded to include not only overtly expressed fear of weight gain but also persistent behavior that interferes with weight gain. The only change in the DSM-IV criteria for bulimia nervosa is a reduction in the required minimum average frequency of binge eating and inappropri ate compensatory be- havior frequency from twice to once weekly. The extensive research that followed the prom- ulgation of preliminary criteria for binge-eating disorder in Appendix B of DSM-IV
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ulgation of preliminary criteria for binge-eating disorder in Appendix B of DSM-IV documented the clinical utility and validity of binge-eating disorder. The only significant dif- ference from the prelimin ary criteria is that the minimum average frequency of binge eating re- quired for diagnosis is once weekly over the la st 3 months, identical to the frequency criterion for bulimia nervosa (rather than at least 2 days a week for 6 months in DSM-IV). Elimination Disorders
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for bulimia nervosa (rather than at least 2 days a week for 6 months in DSM-IV). Elimination Disorders There have been no significant changes in this diagnostic class from DSM-IV to DSM-5. The disorders in this chapter were previously classified under disorders usually first di- agnosed in infancy, childhood, or adolescenc e in DSM-IV and exist now as an independent classification in DSM-5.
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814 Highlights of Changes From DSM-IV to DSM-5 Sleep-Wake Disorders In DSM-5, the DSM-IV diagnose s named sleep disorder related to another mental disorder and sleep disorder related to another medica l condition have been removed, and instead greater specification of coexisting conditions is provided for each sleep-wake disorder. The diagnosis of primary insomnia has been renamed insomnia disorder to avoid the differen- tiation between primary and secondary insomnia. DSM-5 also distinguishes narcolepsy — now known to be associated with hypocretin deficiency—from other forms of hypersomno- lence (hypersomnolence disorder ). Finally, throughout the DSM-5 classification of sleep- wake disorders, pediatric and developmental cr iteria and text are integrated where existing science and considerations of clinical utility support such integration. Breathing-related sleep disorders are divided into three relatively distinct disorders: obstructive sleep apnea hypopnea, central sleep apnea, and sleep-related hypoventilation. The subtypes of circadian rhythm sleep disorders are expanded to include advanced sleep phase type and irregular sleep-wake type, whereas the jet lag type has b een removed. The use of the former “not oth- erwise specified” diagnoses in DSM- IV have been reduced by elevating rapid eye move- ment sleep behavior disorder and restless legs syndrome to independent disorders. Sexual Dysfunctions In DSM-5, some gender-specifi c sexual dysfunctions have been added, and, for females, sexual desire and arousal disorders have been combined into one disorder: female sexual interest/arousal disorder. All of the sexual dysfunctions (except substance/medication-in- duced sexual dysfunction ) now require a minimum duration of approximately 6 months and more precise severity criteria. Genito-pelvic pain/p enetration disorder has been added to
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DSM-5 and represents a merging of vaginismus and dyspareunia, which were highly co- morbid and difficult to distinguish. The diagno sis of sexual aversion disorder has been re- moved due to rare use and la ck of supporting research. There are now only two subtyp es for sexual dysfunctions: lifelong versus acquired and generalized versus situational. To indicate the presence and degree of medical and other nonmedical correlates, the following associated features have been added to the text: partner factors, relationship factors, individu al vulnerability factors, cultural or religious factors, and medical factors. Gender Dysphoria Gender dysphoria is a new diagnostic class in DSM-5 and reflects a change in conceptual- ization of the disorder’s defining features by emphasizing the phenomenon of “gender in- congruence” rather than cross-gender identification per se, as was the case in DSM-IV gender identity disorder. Gender dyspho ria includes separate sets of criteria: for children and for adults and adolescents. For the adolescents an d adults criteria, the previous Criterion A (cross-gender identification) and Criterion B (aversion toward one’s gender) are merged. In the wording of the criteria, “the other sex” is replaced by “the other gender” (or “some alter- native gender”).” Gender instead of sex is used systematically because the concept “sex” is in- adequate when referring to individuals with a disorder of sex development. In the child criteria, “strong desire to be of the other gend er” replaces the previous “repeatedly stated de- sire to be...the other sex” to capture the situat ion of some children who, in a coercive envi-
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ronment, may not verbalize the desire to be of another gender. For child ren, Criterion A1 (“a strong desire to be of the other gender or an in sistence that he or she is the other gender.. .)” is now necessary (but not sufficient), which makes the diagnosi s more restrictive and conser- vative. The subtyping on the basis of sexual or ientation is removed because the distinction is
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is now necessary (but not sufficient), which makes the diagnosi s more restrictive and conser- vative. The subtyping on the basis of sexual or ientation is removed because the distinction is no longer considered clinically useful. A posttransition specifier has been added to identify
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Highlights of Changes From DSM-IV to DSM-5 815 individuals who have undergone at least one medical procedure or treatment to support the new gender assignment (e.g., cross-sex hormon e treatment). Although the concept of post- transition is modeled on the concept of full or partial remission, the term remission has impli- cations in terms of symptom reduction that do not apply directly to gender dysphoria. Disruptive, Impulse-Control, and Conduct Disorders The chapter “Disruptive, Impulse-Control, and Conduct Disorders” is new to DSM-5 and combines disorders that were pr eviously included in the chapte r “Disorders Usually First Di- agnosed in Infancy, Childhood, or Adolescence” (i.e., oppositional defiant disorder; conduct disorder; and disruptive behavior disorder not otherwise specified, now categorized as other specified and unspecified disrup tive, impulse-control, and cond uct disorders) and the chap- ter “Impulse-Control Disorders Not Elsewhere Cl assified” (i.e., intermittent explosive disor- der, pyromania, and kleptomania). These diso rders are all characterized by problems in emotional and behavioral self-control. Notably, ADHD is frequently comorbid with the dis- orders in this chapter but is listed with the neurodevelopmental disorders. Because of its close association with co nduct disorder, antisocial personality disorder is listed both in this chapter and in the chapter “Personality Diso rders,” where it is described in detail. The criteria for oppositional defiant disorder are now grouped into three types: an- gry/irritable mood, argumentative/defiant be havior, and vindictiveness. Additionally, the exclusionary criterion for conduct diso rder has been removed. The criteria for conduct
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the exclusionary criterion for conduct diso rder has been removed. The criteria for conduct disorder include a descriptive features specifier for individuals who meet full criteria for the disorder but al so present with limited prosocial emotions. The primary change in in- termittent explosive disorder is in the type of aggressive outbursts that should be consid- ered: DSM-IV required physical aggression, whereas in DSM-5 verbal aggression and nondestructive/noninjurious physical aggression also meet criteria. DSM-5 also provides more specific criteria defining frequency needed to meet the criteria and specifies that the aggressive outbursts ar e impulsive and/or anger based in nature, and must cause marked distress, cause impairment in occupational or interpersonal functioning, or be associated with negative financial or legal consequences. Furthermore, a minimum age of 6 years (or equivalent developmental level) is now required. Substance-Related and Addictive Disorders An important departure from past diagnostic ma nuals is that the chapter on substance-related disorders has been expanded to include gambling disorder. Another key change is that DSM-5 does not separate the diagnoses of substance abuse and dependence as in DSM-IV. Rather criteria are provided for substance use disorder, accompanied by criteria for intoxication, withdrawal, substance-induced disorders, and unspecified substance-related disorders, where relevant. Within substance use disorders, the DSM-IV recurrent substance-related legal problems criterion has been dele ted from DSM-5, and a new criter ion—craving, or a strong de- sire or urge to use a substance—has been adde d. In addition, the thre shold for substance use disorder diagnosis in DSM-5 is set at two or more criteria, in contrast to a threshold of one or
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more criteria for a diagnosis of DSM-IV substance abuse and three or more for DSM-IV depen- dence. Cannabis withdrawal and caffeine withdrawal are new disorders (the latter was in DSM-IV Appendix B, “Criteria Sets and Axes Provided for Further Study”). Severity of the DSM-5 substance use disorders is based on the number of criteria en- dorsed. The DSM-IV specifier fo r a physiological subtype is eliminated in DSM-5, as is the DSM-IV diagnosis of polysubstance dependence. Early remission from a DSM-5 substance
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dorsed. The DSM-IV specifier fo r a physiological subtype is eliminated in DSM-5, as is the DSM-IV diagnosis of polysubstance dependence. Early remission from a DSM-5 substance use disorder is defined as at least 3 but less than 12 months without meeting substance use disorder criteria (except crav ing), and sustained remission is defined as at least 12 months without meeting criteria (except craving). Additional new DSM-5 specifiers include “in a controlled environment” and “on maintenance therapy” as the situation warrants.
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816 Highlights of Changes From DSM-IV to DSM-5 Neurocognitive Disorders The DSM-IV diagnoses of dementia and amnestic disorder are subsumed under the newly named entity major neurocognitive disorder (NCD). The term dementia is not precluded from use in the etiological subtypes where that te rm is standard. Furthermore, DSM-5 now recog- nizes a less severe level of cognitive impairment, mild NCD, which is a new disorder that per- mits the diagnosis of less disabling syndromes that may nonetheless be the focus of concern and treatment. Diagnostic criteria are provided for both of these disorders, foll owed by diag- nostic criteria for different etiological subtypes. In DSM-IV, individual diagnoses were desig- nated for dementia of the Alzheimer’s type , vascular dementia, and substance-induced dementia, whereas the other neurodegenerative disorders were classified as dementia due to another medical condition, with HIV, head trauma, Parkinson’s disease, Huntington’s disease, Pick’s disease, Creutzfeldt-Jako b disease, and other medical co nditions specified. In DSM-5, major or mild NCD due to Alzheimer’s disease and major or mild vascular NCD have been re- tained, while new separate criteria are now presented for major or mild frontotemporal NCD, NCD with Lewy bodies, and NCDs due to trau matic brain injury, a substance/medication, HIV infection, prion disease, Parkinson’s diseas e, Huntington’s disease, another medical con- dition, and multiple etiologies, respectively. Un specified NCD is also included as a diagnosis. Personality Disorders The criteria for personality disorders in Sectio n II of DSM-5 have not changed from those in
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DSM-IV. An alternative approach to the diag nosis of personality di sorders was developed for DSM-5 for further study and can be found in Section III (see “Alternative DSM-5 Model for Personality Disorders”). For the general criteria for personality disorder, presented in Section III, a revised personality functioning criterion (Criterion A) has been developed based on a literature review of reliable clinical measures of core impa irments central to per- sonality pathology. A diagnosis of personality disorder—trait specified, based on moderate or greater impairment in person ality functioning and the presence of pathological personal- ity traits, replaces personality disorder not ot herwise specified and prov ides a much more in- formative diagnosis for individuals who are not optimally described as having a specific personality disorder. A greater emphasis on pe rsonality functioning and trait-based criteria increases the stability and empiri cal bases of the disorders. Personality functioning and per- sonality traits also can be assessed whether or not the individual has a personality disor- der—a feature that provides clinically useful information about all individuals. Paraphilic Disorders An overarching change from DSM-IV is the addition of the course specifiers “in a controlled environment” and “in remission” to the diagnostic criteria se ts for all the paraphilic disor- ders. These specifiers are added to indicate important changes in an individual’s status. In DSM-5, paraphilias are not ipso facto mental disorders. There is a distinction between paraphil- ias and paraphilic disorders. A paraphilic disorder is a paraphilia that is currently causing dis- tress or impairment to the individual or a pa raphilia whose satisfaction has entailed personal
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tress or impairment to the individual or a pa raphilia whose satisfaction has entailed personal harm, or risk of harm, to others. A paraphilia is a necessary but not a sufficient condition for having a paraphilic disorder, and a paraphilia by it self does not automatically justify or require clinical intervention. The distinction between paraphilias and paraphilic disorders was im- plemented without making any changes to the basi c structure of the diagnostic criteria as they had existed since DSM-III-R. Th e change proposed for DSM-5 is that individuals who meet
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plemented without making any changes to the basi c structure of the diagnostic criteria as they had existed since DSM-III-R. Th e change proposed for DSM-5 is that individuals who meet both Criterion A and Criterion B would now be diagnosed as having a paraphilic disorder. A diagnosis would not be given to individuals whose symptoms meet Criterion A but not Cri- terion B—that is, to individuals who have a paraphilia but not a paraphilic disorder.
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817Glossary of Technical Terms affect A pattern of observable behaviors that is the expression of a subjectively experi- enced feeling state (emotion). Examples of af fect include sadness, elation, and anger. In contrast to mood, which refers to a pervasive and sustained emotional “climate,” affect refers to more fluctuating changes in emot ional “weather.” What is considered the nor- mal range of the expression of affect varies considerably, both within and among dif- ferent cultures. Disturba nces in affect include blunted Significant reduction in the inte nsity of emotional expression. flat Absence or near absence of an y sign of affective expression. inappropriate Discordance between affective expression and the content of speech or ideation. labile Abnormal variability in affect with repeated, rapid, and abrupt shifts in af- fective expression. restricted or constricted Mild reduction in the range and intensity of emotional ex- pression. affective blunting See AFFECT . agitation (psychomotor) See PSYCHOMOTOR AGITATION . agnosia Loss of ability to recognize objects, persons, sounds, shapes, or smells that occurs in the absence of either impairment of the specific sense or significant memory loss. alogia An impoverishment in thinking that is inferred from observing speech and lan- guage behavior. There may be brief and concre te replies to questions and restriction in the amount of spontaneous speech (termed poverty of speech ). Sometimes the speech is adequate in amount but conveys little inform ation because it is overconcrete, overab- stract, repetitive, or stereotyped (termed poverty of content ). amnesia An inability to recall important autobiog raphical information that is inconsis- tent with ordinary forgetting.
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tent with ordinary forgetting. anhedonia Lack of enjoyment from, engagement in , or energy for life’s experiences; def- icits in the capacity to feel pleasure and take interest in things. Anhedonia is a facet of the broad personality trait domain D ETACHMENT . anosognosia A condition in which a person with an illness seems unaware of the exis- tence of his or her illness. antagonism Behaviors that put an individual at od ds with other people, such as an ex- aggerated sense of self-importance with a concomitant expectation of special treat- ment, as well as a callous antipathy toward others, encompassing both unawareness of others’ needs and feelings, and a readiness to use others in the service of self-enhance- ment. Antagonism is one of the five broad PERSONALITY TRAIT DOMAINS defined in Sec- tion III “Alternative DSM-5 Mo del for Personality Disorders.” SMALL CAPS indicate term found elsewhere in this glossary. Glossary definitions were informed by DSM-5 Work Groups, publicly available Internet so urces, and previously published glossaries for mental disorders (World Heal th Organization and American Psychiatric Association).
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818 Glossary of Technical Terms antidepressant discontinuation syndrome A set of symptoms that can occur after abrupt cessation, or marked reduction in dose, of an antidepressant medication that had been taken continuously for at least 1 month. anxiety The apprehensive anticipation of future danger or misfortune accompanied by a feeling of worry, distress, an d/or somatic symptoms of tension. The focus of antici- pated danger may be internal or external. anxiousness Feelings of nervousness or tenseness in reaction to diverse situations; frequent worry about the negative effect s of past unpleasant experiences and future negative possi- bilities; feeling fearful and apprehensive about uncertainty; expecting the worst to happen. Anxiousness is a facet of the broad personality trait domain N EGATIVE AFFECTIVITY . arousal The physiological and psychological state of being awake or reactive to stimuli. asociality A reduced initiative for interacting with other people. attention The ability to focus in a sustained manner on a particular stimulus or activity. A disturbance in attention ma y be manifested by easy DISTRACTIBILITY or difficulty in finishing tasks or in concentrating on work. attention seeking Engaging in behavior designed to attract notice and to make oneself the focus of others’ attention and admiration . Attention seeking is a facet of the broad personality trait domain ANTAGONISM . autogynephilia Sexual arousal of a natal male associated with the idea or image of being a woman. avoidance The act of keeping away from stress-rela ted circumstances; a tendency to cir- cumvent cues, activities, and situations that remind the individual of a stressful event experienced. avolition An inability to initiate and persist in go al-directed activities . When severe enough to be considered pathological, avolition is pervasive and prevents the person from com-
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to be considered pathological, avolition is pervasive and prevents the person from com- pleting many different types of activities (e.g., work, intellectual pursuits, self-care). bereavement The state of having lost through death someone with whom one has had a close relationship. This state includes a range of grief and mourning responses. biological rhythms See CIRCADIAN RHYTHMS . callousness Lack of concern for the feelings or problems of others; lack of guilt or re- morse about the negative or harmful effects of one’s actions on others. Callousness is a facet of the broad personality trait domain ANTAGONISM . catalepsy Passive induction of a posture held against gravity. Compare with WAXY FLEX - IBILITY . cataplexy Episodes of sudden bilateral loss of mu scle tone resulting in the individual collapsing, often occurring in association wi th intense emotions such as laughter, an- ger, fear, or surprise. circadian rhythms Cyclical variations in physiological and biochemical function, level of sleep-wake activity, and emotional state. Circadian rhythms have a cycle of about 24 hours, ultradian rhythms have a cycle that is shorter than 1 day, and infradian rhythms have a cycle that may last weeks or months. cognitive and perceptual dysregulation Odd or unusual thought processes and experi- ences, including DEPERSONALIZATION , DEREALIZATION , and DISSOCIATION ; mixed sleep- wake state experiences; and thought-cont rol experiences. Cognitive and perceptual dysregulation is a facet of the broad personality trait domain P SYCHOTICISM . coma State of complete loss of consciousness.
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Glossary of Technical Terms 819 compulsion Repetitive behaviors (e.g., hand wash ing, ordering, checking) or mental acts (e.g., praying, counting, repeating word s silently) that the individual feels driven to perform in response to an obsession, or according to rules that must be applied rig- idly. The behaviors or mental acts are aimed at preventing or redu cing anxiety or dis- tress, or preventing some dreaded event or situation; however, these behaviors or mental acts are not connected in a realistic way with what they are designed to neutral- ize or prevent or are clearly excessive. conversion symptom A loss of, or alteration in, voluntary motor or sensory functioning, with or without apparent impairment of consciousness. The symptom is not fully ex- plained by a neurological or another medical condition or the direct effects of a sub- stance and is not intentiona lly produced or feigned. deceitfulness Dishonesty and fraudulence; misrep resentation of self; embellishment or fabrication when relating even ts. Deceitfulness is a facet of the broad personality trait domain A NTAGONISM . defense mechanism Mechanisms that mediate the indi vidual´s reaction to emotional conflicts and to external stressors. Some defense mechanisms (e.g., projection, splitting, acting out) are almost invariably maladapt ive. Others (e.g., suppression, denial) may be either maladaptive or adaptive, dependin g on their severity, their inflexibility, and the context in which they occur. delusion A false belief based on incorrect inferenc e about external reality that is firmly held despite what almost everyone else beli eves and despite what constitutes incontro- vertible and obvious proof or evidence to th e contrary. The belief is not ordinarily ac-
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vertible and obvious proof or evidence to th e contrary. The belief is not ordinarily ac- cepted by other members of the person’s culture or subculture (i.e., it is not an article of religious faith). When a false belief involves a value judgment, it is regarded as a delusion only when the judgment is so extreme as to defy credibility. Delusional conviction can sometimes be inferred from an overvalued idea (in which case the individual has an un- reasonable belief or idea but does not hold it as firmly as is the case with a delusion). De- lusions are subdivided according to thei r content. Common types are listed below: bizarre A delusion that involves a phenomenon that the person’s culture would re- gard as physically impossible. delusional jealousy A delusion that one’s sexual partner is unfaithful. erotomanic A delusion that another person, usually of higher status, is in love with the individual. grandiose A delusion of inflated worth, power, knowledge, identity, or special re- lationship to a deity or famous person. mixed type Delusions of more than one type (e.g., EROTOMANIC , GRANDIOSE , PERSE - CUTORY , SOMATIC ) in which no one theme predominates. mood-congruent See MOOD -CONGRUENT PSYCHOTIC FEATURES . mood-incongruent See MOOD -INCONGRUENT PSYCHOTIC FEATURES . of being controlled A delusion in which feelings, impulses, thoughts, or actions are experienced as being under the control of some external force rather than be- ing under one’s own control. of reference A delusion in which events, objects, or other persons in one’s immedi-
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of reference A delusion in which events, objects, or other persons in one’s immedi- ate environment are seen as having a particular and unusual significance. These delusions are usually of a negative or pejo rative nature but also may be grandiose in content. A delusion of reference differs from an idea of reference, in which the false belief is not as firmly held nor as fully organized into a true belief. persecutory A delusion in which the central theme is that one (or someone to whom one is close) is being attacked, harassed, cheated, persecuted, or conspired against.
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820 Glossary of Technical Terms somatic A delusion whose main content pertains to the appearance or functioning of one’s body. thought broadcasting A delusion that one’s thoughts are being broadcast out loud so that they can be perceived by others. thought insertion A delusion that certain of one’s thoughts are not one´s own, but rather are inserted into one’s mind. depersonalization The experience of feeling detached from, and as if one is an outside observer of, one’s mental processes, body, or actions (e.g., feeling like one is in a dream; a sense of unreality of self, perceptual al terations; emotional and/or physical numbing; temporal distortions; sense of unreality). depressivity Feelings of being intensely sad, mise rable, and/or hopeless. Some patients describe an absence of feelings and/or dy sphoria; difficulty recovering from such moods; pessimism about the fu ture; pervasive shame and/or guilt; feelings of inferior self-worth; and thoughts of suicide and suicid al behavior. Depressivity is a facet of the broad personality trait domain D ETACHMENT . derealization The experience of feeling detached from, and as if one is an outside ob- server of, one’s surroundings (e.g., individuals or obje cts are experienced as unreal, dreamlike, foggy, lifeless, or visually distorted). detachment Avoidance of socioemotional experience, including both WITHDRAWAL from interpersonal interactions (rangi ng from casual, daily interactions to friendships and inti- mate relationships [i.e., INTIMACY AVOIDANCE ]) and RESTRICTED AFFECTIVITY , particularly limited hedonic capacity. Detachment is one of the five pathological PERSONALITY TRAIT
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limited hedonic capacity. Detachment is one of the five pathological PERSONALITY TRAIT DOMAINS defined in Section III “Alternative DSM-5 Model for Personality Disorders.” disinhibition Orientation toward immediate gratification, leading to impulsive behav- ior driven by current thoughts, feelings, an d external stimuli, without regard for past learning or consideration of future consequences. R IGID PERFECTIONISM , the opposite pole of this domain, reflects excessive constraint of impu lses, risk avoidance, hyper- responsibility, hyperperfectio nism, and rigid, rule-govern ed behavior. Disinhibition is one of the five pathological PERSONALITY TRAIT DOMAINS defined in Section III “Al- ternative DSM-5 Model for Personality Disorders.” disorder of sex development Condition of significant inborn somatic deviations of the reproductive tract from the norm and/or of discrepancies among the biological indica- tors of male and female. disorientation Confusion about the time of day, date, or season (time); where one is (place); or who one is (person). dissociation The splitting off of clusters of ment al contents from conscious awareness. Dissociation is a mechanism central to dissocia tive disorders. The term is also used to describe the separation of an idea from its emotional significance and affect, as seen in the inappropriate affect in schizophrenia. Of ten a result of psychic trauma, dissociation may allow the individual to maintain allegiance to two contradictory truths while re- maining unconscious of the contradiction. An extreme manifestatio n of dissociation is dissociative identity disorder, in which a person may exhibit several independent per- sonalities, each unaware of the others. distractibility Difficulty concentrating and focusing on tasks; attention is easily divert-
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distractibility Difficulty concentrating and focusing on tasks; attention is easily divert- ed by extraneous stimuli; difficulty main taining goal-focused behavior, including both planning and completing tasks. Distractibilit y is a facet of the broad personality trait domain D ISINHIBITION . dysarthria A disorder of speech sound production due to structural or motor impair- ment affecting the articulatory apparatus. Such disorders include cleft palate, muscle
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Glossary of Technical Terms 821 disorders, cranial nerve disorders, and cerebr al palsy affecting bulbar structures (i.e., lower and upper motor neuron disorders). dyskinesia Distortion of voluntary movements with involuntary muscle activity. dysphoria (dysphoric mood) A condition in which a person experiences intense feelings of depression, discontent, and in some case s indifference to th e world around them. dyssomnias Primary disorders of sleep or wakefulness characterized by INSOMNIA or HYPERSOMNIA as the major presenting symptom. Dyssomnias are disorders of the amount, quality, or timing of sleep. Compare with PARASOMNIAS . dysthymia Presence, while depressed, of two or more of the following: 1) poor appetite or overeating, 2) insomnia or hypersomnia, 3) low energy or fatigue, 4) low self-esteem, 5) poor concentration or difficulty making decisions, or 6) feelings of hopelessness. dystonia Disordered tonicity of muscles. eccentricity Odd, unusual, or bizarre behavior , appearance, and/or speech having strange and unpredictable thoughts; saying un usual or inappropriate things. Eccentric- ity is a facet of the broad personality trait domain P SYCHOTICISM . echolalia The pathological, parrotlike, and apparently senseless repetition (echoing) of a word or phrase just spoken by another person. echopraxia Mimicking the movements of another. emotional lability Instability of emotional experience s and mood; emotions that are easily aroused, intense, and/or out of proportion to events and circumstances. Emo- tional lability is a facet of the broad personality trait domain NEGATIVE AFFECTIVITY .
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empathy Comprehension and appreciation of othe rs’ experiences and motivations; tol- erance of differing perspectives; understand ing the effects of own behavior on others. episode (episodic) A specified duration of time during which the patient has developed or experienced symptoms that meet the diagnostic criteria for a given mental disorder. De- pending on the type of mental disorder, episode may denote a certain number of symptoms or a specified severity or frequency of symptoms. Episodes may be further differentiated as a single (first) episode or a recurrence or relapse of mult iple episodes if appropriate. euphoria A mental and emotional condition in wh ich a person experiences intense feel- ings of well-being, elation, happiness, excitement, and joy. fatigability Tendency to become easily fatigued. See also FATIGUE . fatigue A state (also called exhaustion, tiredness, lethargy, languidness, languor, lassi- tude, and listlessness) usually associated with a weakening or depletion of one’s phys- ical and/or mental resources, ranging from a general state of lethargy to a specific, work-induced burning sensation within one’s muscles. Physical fatigue leads to an in- ability to continue functioning at one’s norm al level of activity. Although widespread in everyday life, this state usually becomes particularly noticeable during heavy exer- cise. Mental fatigue, by contrast, most often manifests as SOMNOLENCE (sleepiness). fear An emotional response to perceived imminent threat or danger associated with urges to flee or fight. flashback A dissociative state during which aspe cts of a traumatic event are reexperi- enced as though they were occurring at that moment. flight of ideas A nearly continuous flow of accele rated speech with abrupt changes
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flight of ideas A nearly continuous flow of accele rated speech with abrupt changes from topic to topic that are usually based on understandable associations, distracting stimuli, or plays on words. When the cond ition is severe, speech may be disorganized and incoherent.
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822 Glossary of Technical Terms gender The public (and usually legally recogniz ed) lived role as boy or girl, man or woman. Biological factors are seen as contri buting in interaction with social and psy- chological factors to gender development. gender assignment The initial assignment as male or female, which usually occurs at birth and is subseque ntly referred to as the “natal gender.” gender dysphoria Distress that accompanies the incongruence between one’s experi- enced and expressed gender and one’s assigned or natal gender. gender experience The unique and personal ways in which individuals experience their gender in the context of the gender roles provided by their societies. gender expression The specific ways in which indivi duals enact gender roles provided in their societies. gender identity A category of social identity that refers to an individual’s identification as male, female or, occasionally, some category other than male or female. gender reassignment A change of gender that can be either medical (hormones, sur- gery) or legal (government reco gnition), or both. In case of medical interventions, often referred to as sex reassignment. geometric hallucination See HALLUCINATION . grandiosity Believing that one is superi or to others and deserves special treatment; self- centeredness; feelings of entitlement; co ndescension toward others. Grandiosity is a facet of the broad personality trait domain ANTAGONISM . grimace (grimacing) Odd and inappropriate facial expressions unrelated to situation (as seen in individuals with CATATONIA ). hallucination A perception-like experience with the clarity and impact of a true percep- tion but without the external stimulation of the relevant sensory organ. Hallucinations should be distinguished from ILLUSIONS , in which an actual external stimulus is
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should be distinguished from ILLUSIONS , in which an actual external stimulus is misperceived or misinterpreted. The person may or may not have insight into the non- veridical nature of the hallucination. One hallucinating person may recognize the false sensory experience, whereas another may be convinced that the ex perience is grounded in reality. The term hallucination is not ordinarily applied to the false perceptions that occur during dreaming, while falling asleep ( hypnagogic ), or upon awakening ( hypno- pompic ). Transient hallucinatory experiences may occur without a mental disorder. auditory A hallucination involving the perception of sound, most commonly of voice. geometric Visual hallucinations involving geometric shapes such as tunnels and funnels, spirals, la ttices, or cobwebs. gustatory A hallucination involving the percepti on of taste (usually unpleasant). mood-congruent See MOOD -CONGRUENT PSYCHOTIC FEATURES . mood-incongruent See MOOD -INCONGRUENT PSYCHOTIC FEATURES . olfactory A hallucination involving the perception of odor, such as of burning rub- ber or decaying fish. somatic A hallucination involving the perception of physical experience localized within the body (e.g., a feeling of electric ity). A somatic hallucination is to be dis- tinguished from physical sensations arisin g from an as-yet-u ndiagnosed general medical condition, from hypochondriacal preoccupation with normal physical sensations, or from a tactile hallucination. tactile A hallucination involving the perception of being touched or of something being under one’s skin. The most common tactile hallucinations are the sensation
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Glossary of Technical Terms 823 of electric shocks and formication (the sensation of somethin g creeping or crawl- ing on or under the skin). visual A hallucination involving sight, which may consist of formed images, such as of people, or of unformed images, such as fl ashes of light. Visual hallucinations should be distinguished from ILLUSIONS , which are misperceptions of real external stimuli. hostility Persistent or frequent angry feelings; anger or irri tability in response to minor slights and insults; mean, nasty, or vengeful behavior. Hostility is a facet of the broad personality trait domain ANTAGONISM . hyperacusis Increased auditory perception. hyperorality A condition in which inappropriate objects are placed in the mouth. hypersexuality A stronger than usual urge to have sexual activity. hypersomnia Excessive sleepiness, as evidenced by prolonged nocturnal sleep, difficul- ty maintaining an alert awake state during the day, or undesired daytime sleep epi- sodes. See also SOMNOLENCE . hypervigilance An enhanced state of sensory sensit ivity accompanied by an exaggerated intensity of behaviors whose purpose is to dete ct threats. Hypervigilance is also accompa- nied by a state of increased anxiety which can cause exhaustion. Other symptoms include abnormally increased arousal, a high responsiveness to stimuli, and a continual scanning of the environment for threats. In hypervigilan ce, there is a perpetual scanning of the envi- ronment to search for sights, sounds, people, beha viors, smells, or anything else that is rem- iniscent of threat or trauma. The individual is placed on high alert in order to be certain
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iniscent of threat or trauma. The individual is placed on high alert in order to be certain danger is not near. Hypervigil ance can lead to a variety of obsessive behavior patterns, as well as producing difficulties with social interaction and relationships. hypomania An abnormality of mood resembling mania but of lesser intensity. See also MANIA . hypopnea Episodes of overly shallow breathing or an abnormally low respiratory rate. ideas of reference The feeling that causal incidents and external events have a particu- lar and unusual meaning that is specific to th e person. An idea of reference is to be dis- tinguished from a DELUSION OF REFERENCE , in which there is a belief that is held with delusional conviction. identity Experience of oneself as unique, with cl ear boundaries betwee n self and others; stability of self-esteem and accu racy of self-appraisal; capaci ty for, and ability to regu- late, a range of emotional experience. illusion A misperception or misinterpr etation of a real external stimulus, such as hear- ing the rustling of leaves as the sound of voices. See also HALLUCINATION . impulsivity Acting on the spur of the moment in response to immediate stimuli; acting on a momentary basis without a plan or consid eration of outcomes; difficulty establish- ing and following plans; a sense of urgenc y and self-harming behavior under emotion- al distress. Impulsivity is a facet of the broad personality trait domain D ISINHIBITION . incoherence Speech or thinking that is essentially incomprehensible to others because word or phrases are joined together without a logical or meaningful connection. This disturbance occurs within clauses, in contrast to dera ilment, in which the disturbance
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disturbance occurs within clauses, in contrast to dera ilment, in which the disturbance is between clauses. This has sometimes been refe rred to a “word salad” to convey the degree of linguistic disorgan ization. Mildly ungrammatica l constructions or idiomatic usages characteristic of a particular region al or cultural backgrounds, lack of educa- tion, or low intelligence should not be co nsidered incoherence. The term is generally not applied when there is evidence that the disturbance in speech is due to an aphasia. insomnia A subjective complaint of difficulty falling or staying asleep or poor sleep quality.
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824 Glossary of Technical Terms intersex condition A condition in which individuals have conflicting or ambiguous bi- ological indicators of sex. intimacy Depth and duration of connection with others; desire and capacity for close- ness; mutuality of regard reflected in interpersonal behavior. intimacy avoidance Avoidance of close or romantic relationships, interpersonal attach- ments, and intimate sexual relationships. Intimacy avoidance is a facet of the broad personality trait domain D ETACHMENT . irresponsibility Disregard for—and failure to honor— financial and other obligations or commitments; lack of respect for—and lack of follow-through on—agreements and promises; carelessness with others’ property. Irresponsibility is a facet of the broad per- sonality trait domain D ISINHIBITION . language pragmatics The understanding and use of language in a given context. For example, the warning “Watch your hands” when issued to a child who is dirty is in- tended not only to prompt the child to look at his or her hands bu t also to communicate the admonition “Don’t get anything dirty.” lethargy A state of decreased mental activity, characterized by sluggishness, drowsi- ness, inactivity, and reduced alertness. macropsia The visual perception that objects are larger than they actually are. Compare with MICROPSIA . magical thinking The erroneous belief that one’s thoug hts, words, or actions will cause or prevent a specific outcome in some way that defies commonly understood laws of cause and effect. Magical thinking may be a part of normal child development. mania A mental state of elevated, expansive, or irritable mood and persistently in- creased level of activity or energy. See also HYPOMANIA .
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creased level of activity or energy. See also HYPOMANIA . manipulativeness Use of subterfuge to influence or control others; use of seduction, charm, glibness, or in gratiation to achieve one’s ends. Manipulativeness is a facet of the broad personality trait domain ANTAGONISM . mannerism A peculiar and characteristic individual style of movement, action, thought, or speech. melancholia (melancholic) A mental state characterized by very severe depression. micropsia The visual perception that objects are smaller than they actually are. Com- pare with MACROPSIA . mixed symptoms The specifier “with mixed features” is applied to mood episodes during which subthreshold symptoms from the oppo sing pole are present. Whereas these con- current “mixed” symptoms are relatively simultaneous, they may also occur closely juxtaposed in time as a waxing and waning of individual symptoms of the opposite pole (i.e., depressive symptoms during hypo manic or manic episodes, and vice versa). mood A pervasive and sustained em otion that colors the perception of the world. Com- mon examples of mood include depression, el ation, anger, and anxiety. In contrast to affect, which refers to more fluctuating change s in emotional “weather,” mood refers to a pervasive and sustained emotional “climate.” Types of mood include dysphoric An unpleasant mood, such as sad ness, anxiety, or irritability. elevated An exaggerated feeling of well-being, or euphoria or elation. A person with elevated mood may desc ribe feeling “high,” “ecstati c,” “on top of the world,” or “up in the clouds.”
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or “up in the clouds.” euthymic Mood in the “normal” range, which implies the absence of depressed or elevated mood.
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Glossary of Technical Terms 825 expansive Lack of restraint in expressing one’s feelings, frequently with an over- valuation of one’s significance or importance. irritable Easily annoyed and provoked to anger. mood-congruent psychotic features Delusions or hallucinations whose content is en- tirely consistent with the typi cal themes of a depressed or manic mood. If the mood is depressed, the content of the delusions or hallucinations would involve themes of per- sonal inadequacy, guilt, disease, death, ni hilism, or deserved punishment. The content of the delusion may include themes of persec ution if these are based on self-derogatory concepts such as deserved puni shment. If the mood is manic, the content of the delusions or hallucinations would involve themes of in flated worth, power, knowledge, or iden- tity, or a special relationship to a deity or a famous person. The content of the delusion may include themes of persecution if thes e are based on concepts such as inflated worth or deserved punishment. mood-incongruent psychotic features Delusions or hallucinations whose content is not consistent with the typical themes of a depr essed or manic mood. In the case of depres- sion, the delusions or hallucinations would not involve themes of personal inadequacy, guilt, disease, death, nihilism, or deserved punishment. In the case of mania, the delu- sions or hallucinations would not involve themes of inflated worth, power, knowledge, or identity, or a special relationsh ip to a deity or a famous person. multiple sleep latency test Polysomnographic assessment of the sleep-onset period, with several short sleep-wake cycles assessed during a single session. The test repeat-
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with several short sleep-wake cycles assessed during a single session. The test repeat- edly measures the time to daytime sleep on set (“sleep latency”) and occurrence of and time to onset of the rapid eye movement sleep phase. mutism No, or very little, verbal response (in the absence of known aphasia). narcolepsy Sleep disorder characterized by period s of extreme drowsi ness and frequent daytime lapses into sleep (sleep attacks). Th ese must have been occurring at least three times per week over the last 3 mont hs (in the absence of treatment). negative affectivity Frequent and intense experiences of high levels of a wide range of negative emotions (e.g., anxiety, depressio n, guilt/shame, worry, anger), and their be- havioral (e.g., self-harm) and interpersonal (e.g., depe ndency) manifestations. Nega- tive Affectivity is one of the five pathological PERSONALITY TRAIT DOMAINS defined in Section III “Alternative DSM-5 Mo del for Personality Disorders.” negativism Opposition to suggestion or advice; be havior opposite to that appropriate to a specific situation or against the wishes of others, including direct resistance to efforts to be moved. night eating syndrome Recurrent episodes of night eating, as manifested by eating after awakening from sleep or ex cessive food consumption afte r the evening meal. There is awareness and recall of the eating. The night eating is not better accounted for by ex- ternal influences such as changes in the in dividual’s sleep-wake cycle or by local social norms. nightmare disorder Repeated occurrences of extended, extremely dysphoric, and well- remembered dreams that usually involve effo rts to avoid threats to survival, security
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remembered dreams that usually involve effo rts to avoid threats to survival, security or physical integrity and that generally occu r during the second half of the major sleep episode. On awakening from the dysphoric dreams, the individual rapidly becomes oriented and alert. nonsubstance addiction(s) Behavioral disorder (also called behavioral addiction) not re- lated to any substance of abuse that shar es some features with substance-induced addiction.
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826 Glossary of Technical Terms obsession Recurrent and persistent thoughts, urges, or images that are experienced, at some time during the disturbance, as intru sive and unwanted and that in most individ- uals cause marked anxiety or distress. The individual attempts to ignore or suppress such thoughts, urges, or images, or to neutralize them with some other thought or ac- tion (i.e., by performing a compulsion). overeating Eating too much food too quickly. overvalued idea An unreasonable and sustained belief that is maintained with less than delusional intensity (i.e., the person is able to acknowledge the possibility that the be- lief may not be true). The belief is not one th at is ordinarily accept ed by other members of the person’s culture or subculture. panic attacks Discrete periods of sudden onset of in tense fear or terror, often associated with feelings of impending doom. During these attacks there are symptoms such as shortness of breath or smothering sensations; palpitations, pounding heart, or acceler- ated heart rate; chest pain or discomfort; choking; and fear of going crazy or losing con- trol. Panic attacks may be unexpected, in wh ich the onset of the attack is not associated with an obvious trigger and instead occurs “ out of the blue,” or expected, in which the panic attack is associated with an obvious trigger, either internal or external. paranoid ideation Ideation, of less than delusional proportions, involving suspicious- ness or the belief that one is being hara ssed, persecuted, or unfairly treated. parasomnias Disorders of sleep involv ing abnormal behaviors or physiological events occurring during sleep or sleep-wake transitions. Compare with DYSSOMNIAS .
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occurring during sleep or sleep-wake transitions. Compare with DYSSOMNIAS . perseveration Persistence at tasks or in particular way of doing things long after the be- havior has ceased to be functional or effe ctive; continuance of the same behavior de- spite repeated failures or clear reasons fo r stopping. Perseveration is a facet of the broad personality trait domain N EGATIVE AFFECTIVITY . personality Enduring patterns of perceiving, relating to, and thinking about the envi- ronment and oneself. P ERSONALITY TRAITS are prominent aspects of personality that are exhibited in relatively consist ent ways across time and across situations. Personality traits influence self and interpersonal func tioning. Depending on their severity, im- pairments in personality functioning and personality trait expression may reflect the presence of a personality disorder. personality disord er—trait specified In Section III “Alternative DSM-5 Model for Per- sonality Disorders,” a proposed diagnostic category for use when a personality disor- der is considered present but the criteria for a specific disorder ar e not met. Personality disorder—trait specified (PD-TS) is defined by significant impairment in personality functioning, as measured by the Level of Personality Functioning Scale and one or more pathological PERSONALITY TRAIT DOMAINS or PERSONALITY TRAIT FACETS . PD-TS is proposed in DSM-5 Section III for further st udy as a possible future replacement for other specified personality disorder and unspecified personality disorder. personality functioning Cognitive models of self and othe rs that shape patterns of emo- tional and affiliative engagement. personality trait A tendency to behave, feel, perceive , and think in relatively consistent ways across time and across situations in which the trait may be manifest.
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ways across time and across situations in which the trait may be manifest. personality trait facets Specific personality components that make up the five broad per- sonality trait domains in the dimensional ta xonomy of Section II I “Alternative DSM-5 Model for Personality Disorders.” For exampl e, the broad domain antagonism has the following component facets: MANIPULATIVENESS , DECEITFULNESS , GRANDIOSITY , ATTEN - TION SEEKING , CALLOUSNESS , and HOSTILITY .
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Glossary of Technical Terms 827 personality trait domains In the dimensional taxonomy of Section III “Alternative DSM- 5 Model for Personality Disorders,” personalit y traits are organized into five broad do- mains: N EGATIVE AFFECTIVITY , DETACHMENT , ANTAGONISM , DISINHIBITION , and P SY- CHOTICISM . Within these five broad trait domains are 25 specific personality trait facets (e.g., IMPULSIVITY , RIGID PERFECTIONISM ). phobia A persistent fear of a specific object, ac tivity, or situation (i.e., the phobic stimu- lus) out of proportion to the actual danger posed by the specific object or situation that results in a compelling desire to avoid it. If it cannot be avoided, the phobic stimulus is endured with marked distress. pica Persistent eating of nonnutritive nonfood substances over a period of at least 1 month. The eating of nonnutritive nonfood substances is inapprop riate to the developmental level of the individual (a minimum age of 2 years is suggested fo r diagnosis). The eat- ing behavior is not part of a culturally supported or socially normative practice. polysomnography Polysomnography (PSG), also known as a sleep study, is a multipa- rametric test used in the study of sleep and as a diagnostic tool in sleep medicine. The test result is called a polysomnogram, also abbreviated PSG. PSG monitors many body functions, including brain (electroencepha lography), eye movements (electro-oculog- raphy), muscle activity or skeletal muscle activation (electromyography), and heart rhythm (electrocardiography).
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rhythm (electrocardiography). posturing Spontaneous and active maintenance of a posture against gravity (as seen in CATATONIA ). Abnormal posturing may also be a si gn of certain injuries to the brain or spinal cord, including the following: decerebrate posture The arms and legs are out straight and rigid, the toes point downward, and the head is arched backward. decorticate posture The body is rigid, the arms are stiff and bent, the fists are tight, and the legs are straight out. opisthotonus The back is rigid and arching, and the head is thrown backward. An affected person may alternate between different postures as the condition changes. pressured speech Speech that is increased in amount, a ccelerated, and difficult or impossi- ble to interrupt. Usually it is also loud an d emphatic. Frequently th e person talks without any social stimulation and may continue to talk even though no one is listening. prodrome An early or premonitory sign or symptom of a disorder. pseudocyesis A false belief of being pregnant that is associated with objective signs and reported symptoms of pregnancy. psychological distress A range of symptoms and experien ces of a person’s internal life that are commonly held to be troubling, confusing, or out of the ordinary. psychometric measures Standardized instruments such as scales, questionnaires, tests, and assessments that are designed to measu re human knowledge, abilities, attitudes, or personality traits. psychomotor agitation Excessive motor activity associated with a feeling of inner tension. The activity is usually nonproductive and repetitious and consists of behaviors such as pac- ing, fidgeting, wringing of the hands, pu lling of clothes, and inability to sit still.
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psychomotor retardation Visible generalized slowing of movements and speech. psychotic features Features characterized by delusions, hallucinations, and formal thought disorder. psychoticism Exhibiting a wide range of culturally incongruent odd, eccentric, or un- usual behaviors and cognitions, including both process (e.g., perception, dissociation)
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