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[ "Origin/Sponsor\n\nCopy Citation:\n\nDownload Citation File:\n\nThese paired systematic reviews examined alert fatigue in the intensive care unit. ", "The first systematic review found several strategies to reduce alerts including prioritizing alerts, developing multipart rules instead of simple alerts, and customizing commercial platforms with end-user input. ", "The second systematic review found that alarm best practices from high reliability industries are not adhered to in intensive care unit settings." ]
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[ "2016 NCAA Beach Volleyball Championship\n\nThe 2016 NCAA Beach Volleyball Championship was the first annual tournament to determine the national champion of NCAA women's collegiate beach volleyball in the United States. ", "The tournament was played on the beaches of Gulf Shores, Alabama, hosted by the University of Alabama at Birmingham, from May 6–8, 2016. ", "The American Volleyball Coaches Association (AVCA) had previously sponsored a beach volleyball championship prior to the NCAA's sanctioning of the sport in 2015.", "\n\nUSC defeated Florida State in the championship match, 3 sets to 0, to clinch the inaugural national title. ", "This was the Trojans' second consecutive national title, having won the last AVCA tournament before the change in the event's sponsor.", "\n\nQualification\nThere is only one national championship for beach volleyball, so all sixty NCAA beach volleyball programs, whether from the Division I, Division II, and Division III, were eligible for the tournament field. ", "A total of eight teams were ultimately invited to contest this championship. ", "Three bids were awarded to the top three teams in both the East and West Regions, and two at-large bids were awarded to the best remaining teams from either region.", "\n\nTeams\n\nFormat\nAll eight teams were subsequently seeded and paired accordingly in the first round of a double-elimination style tournament to be played across a three-day span. ", "Matches were won by the first team to win three-of-five sets.", "\n\nBracket\n\nSee also \n NCAA Women's Indoor Volleyball Championships (Division I, Division II, Division III)\n NCAA Men's National Collegiate Volleyball Championship\n\nReferences\n\nNCAA Men's Volleyball Championship\nNCAA Men's Volleyball Championship" ]
{ "pile_set_name": "Wikipedia (en)" }
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0.007295
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[ "Jefferson and Powell station\n\nJefferson and Powell station is a light rail station in the Fisherman's Wharf district of San Francisco, California, serving the San Francisco Municipal Railway's E Embarcadero and F Market & Wharves heritage railway lines. ", "It is located on Jefferson Street at Powell Street. ", "The station opened on March 4, 2000 with the streetcar's extension to Fisherman's Wharf.", "\n\nReferences\n\nExternal links\nSFMTA: Jefferson St & Powell St\nSFBay Transit (unofficial): Jefferson St & Powell St\n\nPowell\nCategory:Fisherman's Wharf, San Francisco\nCategory:Railway stations in the United States opened in 2000" ]
{ "pile_set_name": "Wikipedia (en)" }
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[ "Related Articles\n\nWashington, D.C. – Washington Mystics General Manager Linda Hargrove announced today that Head Coach Richie Adubato has resigned. ", "Assistant Coach Tree Rollins will assume the position in the interim.", "\n\n“Richie felt that it was in his best interest to leave our team,” said Hargrove. “", "We wish him the best in his future endeavors and look forward to our game tonight. ", "We are confident in the leadership that Tree Rollins can provide along with the rest of our assistant coaches, Marynell Meadors and Crystal Robinson.”", "\n\nRollins enters his second season with the Mystics. ", "He has been an assistant coach in the NBA with the Washington Wizards, Indiana Pacers and the Orlando Magic. ", "He was the head coach with the Greenville Groove of the National Basketball Developmental League. ", "Most recently, Rollins held the job of President and General Manager of the Kentucky Colonels of the American Basketball Association (ABA).", "\n\nHe spent 18 seasons in the NBA, playing with the Atlanta Hawks, Cleveland Cavaliers, and Detroit Pistons before ending his career with the Orlando Magic. ", "During his career, he was considered a defensive force, accumulating 2,542 blocks, 6,249 points and 6,750 rebounds. ", "Fifteen of his 18 seasons, his teams advanced to the playoffs. ", "In the playoffs, he averaged 3.9 points per game, 8.9 blocks per game and 4.6 rebounds per game.", "\n\n\"We look forward to turning the season around with Tree's guidance,\" said Team President and Managing Partner, Sheila Johnson. \"", "Richie has served the Washington Mystics organization well and has been a positive role model for the team. ", "We thank him for all his hard work and his leadership.\"", "\n\nAdubato joined the Washington Mystics in April of 2005 and led the team to the playoffs in 2006 with an 18-16 record. ", "During his tenure with the team, Adubato posted a 33-39 record.", "\n\nWashington will host the 2007 WNBA All-Star game on July 15th Verizon Center. ", "Tickets are available at Ticket Master at (202) 397-SEAT. ", "Season tickets and partial plans for the 2007 Mystics season are currently on sale and can be purchased by calling the Mystics Sales Office at 1-877-DC-HOOP1 or by visiting the Mystics web site at www.washingtonmystics.com." ]
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[ "Brexit Suffers a Snag\n\nAs reported by Reuters news agency today, United Kingdoms’ Prime Minister Theresa May’s Brexit plan suffered a setback. ", "The House of Lords voted 358 to 256 to amend the European Union Notification of Withdrawal Bill. ", "The bill was proposed to enable the UK to leave the European Union. ", "The vote now requires the UK government to protect “EU citizens currently living in Britain, including their residency rights, within three months of triggering exit negotiations.” ", "Prime Minister May’s Conservatives do not have a majority in the upper chamber and hoped to pass the legislation without changes. ", "With a Conservative majority in the lower house, UK’s government can try to overturn the requirement." ]
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[ "Free\ndownloadof all David Irving's booksBookmark\nthe download page to find the latest new\nfree books\n\nDavid Irving\ncomments:\n\nSORRY to say I\nget a lot of complaints from non-Macintosh users\nabout this, and since Macs can also use Zip I\nshall re-upload all the book in Zip compression\nwhen I have time -- say in the next three\nmonths. ", "Meanwhile I have this morning uploaded\na\nZip file of The Mare's\nNest for your\ndelectation." ]
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[ "Q:\n\nHow to return the user_id from the Joomla-Framework on insert/update a (new) user\n\nI try to insert/update a new user to a joomla page from an external script. ", "The following code works very well. ", "However I'll need the user_id of the added or updated user but the script returns just \"useractivate\". ", "\nThe Joomla Forum/Documentation (https://github.com/joomla/joomla-cms/issues/9644) suggests to use \n$db->insertid();\n\nBut I was not able to get this work.", "\nUp to now I tried this:\n$db = JFactory::getDbo();\nvar_dup($db->insertid());\n\nand get the result: 0\nUser Creation \n<?", "php\ndefine( '_JEXEC', 1 );\ndefine('JPATH_BASE', __DIR__ );\ndefine( 'DS', DIRECTORY_SEPARATOR );\n\nrequire_once ( JPATH_BASE .DS.'includes'.", "DS.'defines.php' );\nrequire_once ( JPATH_BASE .DS.'includes'.", "DS.'framework.php' );\n$language = JFactory::getLanguage();\n$language->load('com_users', JPATH_BASE);\nJFactory::getLanguage()->load('mod_login', JPATH_BASE, 'de-DE', true);\n\n$app = JFactory::getApplication('site');\n$app->initialise();\nrequire_once(JPATH_BASE.DS.'components'.", "DS.'com_users'.", "DS.'models'.", "DS.'registration.php');\n$model = new UsersModelRegistration();\njimport('joomla.mail.helper');\njimport('joomla.user.helper');\n\n$username = 'jimporttest';\n$name = 'J Port2';\n$email = 'test@test.de';\n$password = 'test';\n$data = array(\n 'username' => $username,\n 'name' => $name,\n 'email1' => $email,\n 'password1' => $password,\n 'password2' => $password,\n 'block' => 0\n);\n$return = $model->register($data);\nvar_dump($return);\n\nPS: I have to use the joomla-framework and can not use a simple mysql query because the new user has to activate its account and set easily a new password.", "\n\nA:\n\nAlternatively you can load user as per username used to create user.", "\n$return = $model->register($data);\nif($return == 'useractivate'){\n $userid = JFactory::getUser($username)->id;\n}\n\n" ]
{ "pile_set_name": "StackExchange" }
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[ "Molecular similarity based on DOCK-generated fingerprints.", "\nAn alternative method for defining molecular similarity is presented. ", "By using the docking program DOCK and a reference panel of protein binding sites, fingerprints for a set of molecules have been generated, based on calculated interaction energies. ", "These binding patterns allowed us to calculate matrices of similarity coefficients which subsequently were used for nearest-neighbor searches within the database. ", "Our results indicate that the method is suitable for finding significant similarities of compounds of the same biological activity. ", "Although the overall performance of a traditional 2D similarity method is better in the test systems investigated, our 3D approach can be regarded as complementary since it is able to detect similarities independent of the covalent structure of the compounds. ", "Thus it should be a useful 3D database-searching tool for rational lead discovery." ]
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[ "1. ", "Kniight (irving and williams will be out, so i choose the best available PG.)", "\n\n2.", "\n- trade Bargs for a top 4-7 draft pick 2011 + a good SF player (D wright) and draft biyombo with the pick.", "\n- buy the right of Sofoklís Schortsianítis and bring him here for MLE.", "\n- trade barbosa to chicago for the first charlotte 2012 pick and asik.", "\n- resign evans as our vet leader.", "\n- resign weems as the sg backup\n\n- \"if possible\" trade caldy for a mid/late first and a 2nd round pick (not in 2011).", "\n\n3.", "\nwith a team like this :\nBayless/knight/\"caldy\"\nDD/weems\nJJ/D wright/kleiza\ndavis/amir/biyombo\nsofo/asik/evans\n\nthat's twice i've seen sofo's name mentioned today. ", "i remember when he was drafted, he received as much hype as biyombo (potential top ten pick) and ended up being selected in the second round. ", "hasn't he been dealing with fatness issues? ", "regardless, having him as our starting center is a bit ridiculous, don't you think? ", "i doubt he'd have the conditioning to play 15 minutes of NBA ball.", "\n\nalso, i don't agree with Bargs for draft picks. ", "although i wouldn't mind having one in return, we'd need a legitimate player in return for him. ", "taking some project for a proven player isn't the smartest move.", "\n\nbarbose for asik and the bobcats first isn't going to happen. ", "the bulls wouldn't trade asik for mayo and it's quite possible that the bobcats are going to be in contention of the 1st pick in next years draft.", "\n\nPut you in the GM shoes right now, with an expected 3th draft pick and the current roster. ", "forget about the new CBA too.", "\n\nwhat things this summer would you do :\n1. ", "who would you draft at the 3th ?", "\n2. ", "what trade are you willing to do ?", "\n3. ", "what will you do with the coach situation ?", "\n\n1. ", "Try to move up to 1 or 2 if at all possible, if not BPA\n2. ", "Bargs and Jose should be traded if a decent deal can be had. ", "Doesn't have to be great.", "\n3. ", "Fire Triano and target Lawrence Frank and go after him hard\n\n1. ", "Assuming Williams and Irving are gone, I'd grab Kemba Walker. ", "As of now we still don't know who will sneak up in draft ratings so we'll see after the combine/workouts.", "\n\n2. ", "I would by any means try and S&T for Wilson Chandler. ", "I don't know if Denver would bite on Bargnani but Chandler would do wonders for the team at the 3.", "\nAn alternate trade for Varejao or Bynum wouldn't look too bad.", "\n\n1. ", "Try to move up to 1 or 2 if at all possible, if not BPA\n2. ", "Bargs and Jose should be traded if a decent deal can be had. ", "Doesn't have to be great.", "\n3. ", "Fire Triano and target Lawrence Frank and go after him hard\n\nWhy are you so obsessed with Lawrence Frank? ", "Is it because he coached the Nets to the worst record in NBA history?", "\n\nThis is tough because there are so many possible factors starting first with BC - will he be here. ", "If he is then Triano I think will stay till at least the all star break. ", "If BC is gone then so is Triano. ", "So under the assumption the BC stays and Triano is here then:\n\n1) draft - no idea as we don't know where we are picking till the 17th. ", "If no 1 Williams, then I would select the best available pg, at #2 Irving, at #3-4 Knight or #5-6 Walker.", "\n\n2) trade - whoever the Raps draft, the team still needs a center. ", "This is big cause imo Bargs or Davis will have to go forcing the team to choose a style of play, finally - PF on the perimeter or PF in the paint. ", "IMO that will be decided by the center that we are able to get. ", "Either Davis or Bargs will be able to bring something back. ", "No one on the roster is untouchable so if a deal that makes the Raps better comes along then it should happen.", "\n\n3) Coach - I would keep Triano to see what he can do with a healthy roster, a set style of play and more talent. ", "I would believe he has till the All Star break to do this.", "\n\nget the bpa, unless he's a 2 or 4. ", "Our needs are across the board and drafting for need is pretty much drafting any position\n\nas far as bargnani, I wouldn't try to get an established player, unless he's young and with potential, somebody like evan turner for example (not turner per se, but that profile - potential marked by some kind of dissapointment). ", "Nobody's going to trade you their prized young assets for bargnani, unless they can't afford to keep them (i.e. don't want to overpay them).", "\n\nand whatever you do, stay away from character issues. ", "For all the dissapointments, at least we had good citizens here, if we get somebody like cousins, even that remaining virtue would be lost\n\nand we're not getting a #4 pick in 2011 for bargnani, I doubt we'd be getting that for davis or derozan to be honest. ", "That draft is supposed to be a major one, very deep and very strong at the top. ", "People are comparing it with the '03 draft from what I've read.", "\n\nand we're not getting a #4 pick in 2011 for bargnani, I doubt we'd be getting that for davis or derozan to be honest. ", "That draft is supposed to be a major one, very deep and very strong at the top. ", "People are comparing it with the '03 draft from what I've read.", "\n\n1. ", "who would you draft at the 3th ?", "\nIrving, Williams, Walker in that order\n\n2. ", "what trade are you willing to do ?", "\nhard to say a particular trade. ", "but I'd trade anyone outside of Davis and probably DeRozan unless the price is right\nIbaka, Harden (OKC can't afford all these guys in the future), Gasol, J Smith, AK47, Oden, Hayes, Brewer\n\n3. ", "what will you do with the coach situation ?", "\nfire Triano. ", "hire Mike Budenholzer\n\nthat's twice i've seen sofo's name mentioned today. ", "i remember when he was drafted, he received as much hype as biyombo (potential top ten pick) and ended up being selected in the second round. ", "hasn't he been dealing with fatness issues? ", "regardless, having him as our starting center is a bit ridiculous, don't you think? ", "i doubt he'd have the conditioning to play 15 minutes of NBA ball.", "\n\nalso, i don't agree with Bargs for draft picks. ", "although i wouldn't mind having one in return, we'd need a legitimate player in return for him. ", "taking some project for a proven player isn't the smartest move.", "\n\nbarbose for asik and the bobcats first isn't going to happen. ", "the bulls wouldn't trade asik for mayo and it's quite possible that the bobcats are going to be in contention of the 1st pick in next years draft." ]
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[ "Comparative Biochemical Analysis of Cellulosomes Isolated from Clostridium clariflavum DSM 19732 and Clostridium thermocellum ATCC 27405 Grown on Plant Biomass.", "\nThe cellulosome is a supramolecular multienzyme complex formed via species-specific interactions between the cohesin modules of scaffoldin proteins and the dockerin modules of a wide variety of polysaccharide-degrading enzymes. ", "Here, we report a comparative analysis of cellulosomes prepared from the thermophilic anaerobic bacteria Clostridium (Ruminiclostridium) clariflavum DSM 19732 and Clostridium (Ruminiclostridium) thermocellum ATCC 27405 grown on delignified rice straw. ", "The results indicate that the isolated C. clariflavum cellulosome exhibits lower activity for insoluble cellulosic substrates and higher activity for hemicellulosic substrates, especially for xylan, compared to the isolated C. thermocellum cellulosome. ", "The C. clariflavum cellulosome was separated into large and small complexes by size exclusion chromatography, and the high xylanase activity of the intact complex is mainly attributed to the small complex. ", "Furthermore, both C. clariflavum and C. thermocellum cellulosomes efficiently converted delignified rice straw into soluble sugars with different compositions, whereas a mixture of these cellulosomes exhibited essentially no synergy for the saccharification of delignified rice straw. ", "This is the first study to report that isolated C. clariflavum cellulosomes exhibit greater xylanase activity than isolated C. thermocellum cellulosomes. ", "We also report the effect of a combination of intact cellulosome complexes isolated from different species on the saccharification of plant biomass." ]
{ "pile_set_name": "PubMed Abstracts" }
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[ "Extracorporeal blood treatment means taking the blood from a patient, treating the blood outside the patient, and returning the treated blood to the patient. ", "Extracorporeal blood treatment is typically used to extract undesirable matter or molecules from the patient's blood, and/or to add beneficial matter or molecules to the blood. ", "Extracorporeal blood treatment is used with patients incapable of effectively eliminating matter from their blood, for example, in the case of a patient who is suffering from temporary or permanent kidney failure. ", "These and other patients may undergo extracorporeal blood treatment to add to or to eliminate matter from their blood, to maintain an acid-base balance or to eliminate excess body fluids, for instance.", "\nIn a variety of extracorporeal blood treatments, one or more liquids may be supplied to the extracorporeal blood treatment apparatus for use during the treatments and one or more liquids may be collected as a part of the treatments. ", "Both the supplied and collected liquids may be stored in one or more reservoirs. ", "Those reservoirs may, during the course of treatment of a single patient, need to be replaced as they are either emptied (in the case of liquids supplied as a part of the treatment) or are filled to capacity (in the case of liquids collected as a part of the treatment).", "\nAlthough many extracorporeal blood treatment apparatus include displays used to monitor the operation of the apparatus as well as the status of any reservoirs attached to the apparatus, those displays are typically physically remote from the reservoirs themselves. ", "For example, in many extracorporeal blood treatment apparatus the reservoirs are provided in the form of bags that hang from the bottom of a housing containing the extracorporeal blood treatment apparatus, while displays are typically located higher on the machine so that they are closer to eye level for the user." ]
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[ "Jones et al. ", "in WO No. ", "84/03044 disclose renin inhibiting tetra-, penta-, or hexapeptide analogues of the formula EQU X--D--E--A--B--Z--W\nwhere X and W are terminal groups; D, E, B and Z, of which any one or, except with reduced analogues, two may be absent, are aromatic, lipophilic or (in the case of E) aromatic, lipophilic, or basic amino acid or amino acid analogue residues, and A is an analogue of a lipophilic or aromatic dipeptide residue wherein the peptide link is replaced by one to four-atom carbon or carbon-nitrogen link which as such or in hydrated form is an unhydrolyzable tetrahedral analogue of the transition state of the peptide bond as given above. ", "In particular, A is defined as ##STR2## wherein M can be --CH--OH.", "\nSzelke et al. ", "in European patent application No. ", "104,041 disclose renin inhibitory polypeptides including the partial sequence EQU X--A--B--Z--W\nand EQU X--Phe--His--A--B--Z--W\nwherein A is ##STR3## and G is ##STR4## X is hydrogen, protecting group, or an amino acyl residue, B is a lipophilic amino acyl residue, and Z plus W are an amino alcohol residue or Z is aminoacyl and W is hydroxy, ester, amide, etc.", "\nMatsueda et al. ", "in European patent application No. ", "128,672 disclose renin inhibiting peptides of the formula ##STR5## wherein But represents an isobutyl or sec-butyl group and X includes a group of the formula --CH(R.sup.2)--Y.\nGordon et al. ", "in U.S. Pat. ", "No. ", "4,514,391 disclose hydroxy substituted peptide compounds of the formula ##STR6## which possess angiotensin converting enzyme or enkephalinase inhibition activity." ]
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[ "James Semple Kerr\n\nJames Semple Kerr (6 July 1932 – 15 October 2014) was an architectural historian and heritage practitioner in Australia, who was prominent in the drafting of the original Burra Charter and its subsidiary documents, and developing standards for conservation practice, particularly in relation to conservation assessments and management reports such as conservation management plans. ", "Kerr's influence in the conservation movement is most notable for his publication of the Conservation Plan, which has guided building conservation in Australia and around the world.", "\n\nWork and contributions\n\nKerr undertook a doctorate at the Institute of Advanced Architectural Studies, at the University of York in 1974. ", "In 1978 he took up the position as Assistant Director at the Australian Heritage Commission in Canberra. ", "He was also an assistant director of the National Trust of Australia (NSW).", "\n\nKerr was prominent in heritage conservation in Australia for over 40 years and was an early member of Australia ICOMOS, taking a major role in the formulation of the Burra Charter and its Guidelines. ", "His publication in 1982 of The Conservation Plan: A guide to the preparation of conservation plans for places of European cultural significance was a landmark in Australian conservation. ", "The Conservation Plan is widely used by heritage practitioners and property owners in Australia, and worldwide as a primary guide to the process of researching, documenting and managing historic places in accordance with the Burra Charter, through a logical process. ", "First published by the National Trust of Australia (NSW) in 1982, it has subsequently been reprinted in expanded form over seven editions and twelve printing impressions. ", "The concept has been adopted worldwide as a critical process for conserving heritage places, for example in the British Heritage Lottery Fund guidance note Conservation Plans for Historic Places.", "\n\nLife and family\n\nKerr was born on 6 July 1932 in Rockhampton, Queensland, son of grazier James Kerr and Iris (née Rudd), and he and his sisters were raised on Hampden Downs Station. ", "Initially home schooled by his mother, he later attended Toowoomba Preparatory School and then King's School Parramatta. ", "He joined the Royal Australian Naval Volunteer Reserve in 1952, leaving in 1956. ", "He became an accomplished oarsman in Queensland and later NSW state competitions, but missed out narrowly on selection for the 1956 Olympics.", "\n\nKerr married Joan Lyndon (1938–2004), an art and architectural historian, whom he had met in 1957. ", "They wed on 30 November 1960 at All Saints Anglican Church, Brisbane, moving to Sydney soon after. ", "Kerr was working in management at Qantas at the time. ", "In 1963, Qantas posted Kerr to Geneva, and then to London, where Joan enrolled them both in a history of art course run by Nikolaus Pevsner at Birkbeck College. ", "They returned to Australia in 1968, settling in Cremorne in Sydney. ", "They had two children, a daughter, Tamsin and a son, James.", "\n\nKerr's wife Joan died in 2004, and James published \"Joan Kerr, A Pictorial Biography, 1938–2004\" in 2006. ", "He also published letters from his son (also James Semple), who worked as an outback stockman.", "\n\nKerr died on Wednesday 15 October 2014 at Elizabeth Lodge nursing home, Willoughby, New South Wales. ", "His final project had been to catalogue the works of his wife and of his own. ", "His personal papers, along with those of his wife, and records of his family history have been deposited, in bound volumes, in the National Library of Australia in Canberra.", "\n\nAwards\n\nKerr was made Honorary Life Member of the National Trust (NSW) in 1992 and was awarded the NSW National Trust Heritage Award with his wife Joan in 1995, and they received the lifetime achievement award in 2007, and he was made an Honorary Life Member of Australia ICOMOS in 2003 and International Honorary Life Member in 2011. ", "He was also made a Member of the Order of Australia in 1999, \"...for service to heritage conservation through organisations including the Australian International Council on Monuments And Sites, and The New South Wales Branch of the National Trust of Australia\".", "\n\nSelected publications\n\n 1981: Fannie Bay Gaol Precinct conservation management plan \n 1984: Design for convicts: An account of design for convict establishments in the Australian colonies during the transportation Sydney: Library of Australian History in association with the National Trust of Australia (NSW) and the Australian Society for Historical Archaeology \n 1984: Cockatoo Island, penal and institutional remains: An analysis of documentary and physical evidence and an assessment Sydney: National Trust of Australia (NSW), \n 1985: Goat Island: An analysis of documentary and physical evidence and an assessment of significance \n 1986: Fort Denison: An investigation for the Maritime Services Board of NSW \n 1986: Fort Denison: an investigation for the Maritime Services Board of NSW \n 1987: Admiralty House: A conservation plan prepared for the Department of Housing and Construction \n 1988: Out of sight, out of mind: Australia's places of confinement, 1788–1988 Sydney: S.H. Ervin Gallery, National Trust of Australia (NSW), \n 1989: Elephant castle: an investigation of the significance of the head office building of the Commonwealth Banking Corporation of Australia, Sydney, Sydney: National Trust New South Wales \n 1990:The Haymarket and The Capitol: A conservation plan for the area bounded by George, Campbell, Pitt and Hay Streets, Sydney \n 1990: Tamworth Gaol: its development, use, significance and conservation \n 1991 & 2002: Sydney Observatory: a conservation plan for the site and its structures, Sydney: Museum of Applied Arts and Sciences, \n 1992: Fremantle Prison: A policy for its conservation \n 1992: Anderson Stuart’s Medical School: A Plan for Its Conservation \n 1993: Sydney Opera House: an interim plan for the conservation of the Sydney Opera House and its site, published by National Trust, second edition 1999, third (revised) edition 2003 published by The Sydney Opera House Trust, Sydney, NSW.", "\n 1993: (revised 2001), Yungaba Immigration Depot: a plan for its conservation \n 1994: Goulburn Correctional Centre: A Plan for the Conservation of the Precinct and Its Buildings \n 1995: Parramatta Correctional Centre: Its Past Development and Future Care\n 2000: Conservation plan: a guide to the preparation of conservation plans for places of European cultural significance (5th edition) Sydney: National Trust of Australia (NSW) \n 2002: Sydney Observatory: a conservation plan for the site and its structures, 2nd rev. ", "ed. ", "Sydney: Museum of Applied Arts and Sciences \n 2004: Conservation plan: a guide to the preparation of conservation plans for places of European cultural significance, Sydney: Published by J.S. Kerr on behalf of the National Trust of Australia (NSW)\n 2006: Joan Kerr: a pictorial biography, 1938–2004 Cremorne, NSW\n\nReferences\n\nExternal Source\n\n Bronwyn Hanna \"Obituary – James Semple Kerr, Conservationist 6th July 1932 to 15th October 2014\" Engineering Heritage Australia Magazine Volume 1 No.5 December 2014\n\nCategory:Conservation architects\nCategory:Australian historians\nCategory:Australian architecture writers\nCategory:1932 births\nCategory:2014 deaths\nCategory:Historians of Australia\nCategory:Members of the Order of Australia" ]
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0.012368
5
[ "A day doesn’t go by without Grandma Peggy asking me “who in the hell in their right mind would vote for Obama?” ", "She has a problem believing the intelligent people in America are intoxicated with the elixir of socialism. ", "I often argue that the people who voted for him are not necessarily very intelligent at all. ", "In fact, most are downright stupid.", "\n\nA good friend, now retired from the Air Force as a Colonel, sent the evidence I needed to make my point to Peg. ", "This cutout from a newspaper is a little hard to read, but trust me it is worth reading, you will laugh your ass off. ", "Remember these people walk among us.", "\n\nI blame the educational system for this stupidity. ", "We are born smarter than this proud Democrat.", "\n\nOne Response\n\nKnowing there are many, many, many democrats who are proud to have someone else control every aspect of their lives, lets me know the Republic is in GRAVE DANGER. ", "When government CONTROLS everything, LIFE, LIBERTY, and PURSUIT OF HAPPINESS are lost.", "\n” WE THE PEOPLE ” must make a stand. ", "Chuck\n\nComments are closed.", "\n\nEmail Subscription\n\nEnter your email address to subscribe to this blog and receive notifications of new posts by email.", "\n\nConfused about Islam, Muslims, Taqiyya, Kitman, The Islamic State, and Sharia? ", "I've spent 14 years studying these confused beings. ", "They are not at all what they want us to believe, especially those who are ruled by al Qaeda , ISIS and the Muslim Brotherhood as well as those who commit overt and covert Jihad while practicing Sharia tortures upon women\n\n“ The limitation of riots, moral questions aside, is that they cannot win and their participants know it. ", "Hence, rioting is not revolutionary but reactionary because it invites defeat. ", "It involves an emotional catharsis, but it must be followed by a sense of futility. ” ", "~ Martin Luther King, Jr." ]
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0.009491
5
[ "I’ve attended a weekly gentle yoga class at the Pink Lotus Studio (on Kings Highway in Swedesboro) for the past five years and wouldn’t miss it. ", "My 79 year old body is more healthy and flexible than it would be had I not started the practice.", "\n\nI’m frequently amazed at the condition of people who are 20 years younger. ", "They barely get around without assistance—limping, walking with canes, using walkers, and getting knee or hip replacements.", "\n\nOld age creeps up on you. ", "Many don’t have a clue about what’s taking place. ", "Others may casually mention one or two things they’re experiencing, but haven’t made an age/body connection.", "\n\nMore than a few are in total denial. ", "Truth is, if you don’t know what’s going on, you can’t do anything about it.", "\n\nTake a look at some of the signs of growing old. ", "Many are so subtle they’re barely noticeable…at first. ", "They hide, settle in, and become ensconced as part of our lives.", "\n\nScan your body; ask these questions. ", "Has your energy level decreased even slightly? ", "Is climbing stairs more difficult? ", "Does standing from a seated position take more effort? ", "Experiencing more aches than in the past? ", "Stopped exercising and/or participating in sports? ", "Feel stiff in new places? ", "What can you add to this list?", "\n\nGentle Yoga is for all ages and addresses this downward spiral. ", "It emphasizes stretching and strengthening the body because, as we age, stiffness and weakness sneak up on us. ", "It’s gentle because you do only what you can do at a comfortable pace.", "\n\nYou gradually become aware of what’s going on in the body you’ve taken for granted. ", "As you practice the movements, the mind becomes engaged. ", "You learn to focus. ", "You begin to learn what you need to do to feel better.", "\n\nStrength, flexibility and mobility return. ", "You start remembering how it used to be. ", "And this motivates you to get to that place again.", "\n\nWorking out the ‘kinks’ that the body has accumulated over the years is a valuable byproduct of yoga practice. ", "Everyone has some. ", "Deposited from early childhood to the present, they are reactions to life’s difficulties.", "\n\nAs one develops more body awareness, it’s important to identify the sources of discomfort. ", "These ‘kinks’ cause stress that lodge anywhere in the body.", "\n\nThat stiff neck can be a result of internalized hurt and anger in response to a betrayal. ", "Tightness and shoulder aches can be caused by carrying a heavy load, such as caring for someone terminally ill.", "\n\nLower back ache can be due to the struggle to make ends meet when your mate took off leaving you and the children. ", "Leg aches can be due to the heaviness of someone leaning on you, refusing to carry his/her own weight.", "\n\nResentment of an abusive parent can be pushed down in the feet when escape was not possible (think incest). ", "Being afraid left a deposit that affected your breathing when you were sent to the principal’s office. ", "Feeling tight all over is the result of a bitter, contentious divorce.", "\n\nThe list is endless; the causes myriad. ", "In middle school I remember being depressed and dreading each day because of bullying. ", "I’ve experienced other discomforts in various parts of my body for many different reasons.", "\n\nAnd, due to their insidious nature, I have been totally unaware of their presence. ", "Go figure.", "\n\nIf any of these issues resonate with you, you can be certain they’re lodged somewhere in your body and causing discomfort. ", "Some are silent! ", "But they all need to be worked out.", "\n\nYoga practice addresses this. ", "It has for me. ", "My focus and motivation has helped me get rid of negative baggage I’ve carried for years – as far back as middle school and earlier.", "\n\nMy balance, flexibility and mobility has improved and my overall health is better. ", "This is why I Thank God for Yoga.", "\n\nI urge everyone to release, relax and feel better in 2016. ", "You owe it to yourself. ", "Join a yoga class today.", "\n\nIf you’re near Swedesboro, I suggest you call 856-975-0789 or visit pinklotusnj.com to check the class schedules. ", "Your body will thank you." ]
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0.000259
5
[ "[A MODULATORY INFLUENCE OF THE iNOS ON THE FUNCTIONAL ACTIVITY OF THE KATP-CHANNELS IN CORONARY VESSELS OF RATS ADAPTED TO THE STRESS].", "\nIn the experiments carried out on the isolated by Langendorff's method hearts which were perfused at the constant coronary flow it was studied influence of iNOS-derived NO on the functional activity of the KATP-channels in the coronary vascular smooth muscle cells following formation of the adaptation to the stress. ", "As an adaptation to the short stress as a 6-hours immobilization stress result in increase of NO production and rise of expression of gene iNOS; however, adaptation in contrast to the stress leads to moderate accumulation of iNOS against the background unchanged systemic activity of еNOS and in the absence of systemic low-grade inflammation. ", "After an adaptation to the short stress or after 6 hours of immobilization the functional glybenclamid-inhibiting activity of the KATP-channels was suppressed. ", "Nevertheless, after prolonged immobilization suppressed activity of the channels was abolished after blockage of iNOS, whereas iNOS blockage in adapted animals leads not only to the recovery but even to the hyperactivation of the KATP-channels. ", "Hence, increase in NO production which is typical for the adaptation, limits activation of the KATP-channels thus creating a strong link between these channels activity and NO produced by iNOS." ]
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0.000522
5
[ "Transportation in Memphis, Tennessee\n\nMemphis, Tennessee has developed into a major Mid-American commercial and transportation hub because of its location on the Mississippi River and a convergence of numerous rail and highway links. ", "Four rail and highway bridges cross the Mississippi River at Memphis. ", "In addition, Memphis International Airport has become the world's largest airfreight terminal.", "\n\nTravel and shipment of freight are facilitated by two major Interstate highways, I-40 and I-55, that intersect at Memphis. ", "I-240 is a highway spur that carries traffic around the city. ", "A large volume of railroad freight traffic moves through Memphis, thanks to two Mississippi River railroad crossings and the convergence at Memphis of east-west with north-south rail routes. ", " In addition, Memphis is the second busiest cargo port on the Mississippi River.", "\n\nLocal public transportation in the Memphis area is provided by the Memphis Area Transit Authority.", "\n\nHighways\n\nInterstates\n\nInterstate 40 (I-40), its spur highway I-240 and I-55 are the main freeways in the Memphis area. ", "I-40 and I-55 (along with rail lines) cross the Mississippi at Memphis from the state of Arkansas.", "\n\nI-22 connects the southeast part of Memphis with Mississippi. ", "I-269 is an outer beltway around the city, partially in Mississippi.", "\n\nFuture I-69 is planned for the Memphis area.", "\n\nU.S. Highways\nMemphis is served by seven primary U.S. highways, more than any other city in the Southeastern United States.", "\n\nU.S. Route 51 (US 51) enters Memphis from the south along with SR 3 as Elvis Presley Boulevard. ", "The road changes names to Bellevue Boulevard before meeting Union Avenue. ", "US 51 continues along Union Avenue to Danny Thomas Boulevard, which eventually changes into Thomas Street. ", "The route then heads north towards Millington.", "\n\nUS 61 enters the city from the south along with SR 14 as Third Street. ", "The highway travels to E.H. Crump Boulevard, turning west and eventually crossing the Memphis & Arkansas Bridge.", "\n\nUS 64 enters with Interstate 55 (I-55) on the Memphis & Arkansas Bridge, traveling along various streets until eventually heading east from the city along Stage Road towards Somerville.", "\n\nUS 70 and US 79 travel concurrently in the entirety of the city, traveling from the Memphis & Arkansas Bridge along various streets until eventually meeting Summer Avenue. ", "The two highways continue to the northeast, paralleling I-40 towards Brownsville.", "\n\nUS 72 travels through Memphis along Poplar Avenue, one of the city's main roads. ", "It leaves the city at the city limits of Germantown.", "\n\nUS 78 leaves the city traveling to the southeast. ", "The west end of US 78 begins in Memphis on Linden Avenue at the intersection of 2nd Street. ", "As it leaves Memphis, US 78 follows Lamar Avenue, historically known as Pigeon Roost Road for the nestings of passenger pigeons formerly in the vicinity.", "\n\nRailroad\n\nA large volume of railroad freight traffic moves through Memphis, thanks to two Mississippi River railroad crossings and the convergence of east-west rail routes with north-south routes.", "\n\nMemphis had two major rail passenger stations, Memphis Union Station, razed in early 1969, and Memphis Central Station, which has been renovated. ", "The Central Station renovation was completed in November 1999.", "\n\nCity of New Orleans\nCentral Station serves Amtrak's City of New Orleans route between Chicago and New Orleans.", "\n\nAmtrak Train 59, the southbound City of New Orleans, is scheduled to depart Memphis at 6:50am daily with service to Greenwood, Yazoo City, Jackson, Hazlehurst, Brookhaven, McComb, Hammond, and New Orleans.", "\n\nAmtrak Train 58, the northbound City of New Orleans, is scheduled to depart Memphis at 10:40pm daily with service to Newbern-Dyersburg, Fulton, Carbondale, Centralia, Effingham, Mattoon, Champaign-Urbana, Kankakee, Homewood, and Chicago.", "\n\nPublic transportation\n\nThe Memphis Area Transit Authority (MATA) provides the area with scheduled city bus service and with paratransit service for persons with disabilities. ", "Three express bus lines were added in 2008 to provide service into Downtown Memphis from outer suburbs.", "\n\nMATA also operates a downtown trolley system with 24 stations along three lines. ", "The trolley system is in the process of expanding into a regional system.", "\n\nMemphis International Airport\n\nMemphis is served by Memphis International Airport, which handled more cargo than any other airport in the world until 2010. ", "It remains the busiest cargo airport in the United States as of 2018.", "\n\nThe airport is the international cargo hub for FedEx and was a passenger hub for Delta Air Lines after their merger with Northwest Airlines in 2008. ", "Other passenger airlines providing service to the airport are Air Canada, American Airlines, and United Airlines.", "\n\nThe Tennessee Air National Guard operates the 164th Airlift Wing at the airport.", "\n\nMississippi River port\nMemphis also has the 2nd biggest cargo port on the Mississippi River (the 4th biggest inland port in the United States): The International Port of Memphis. ", "The International Port of Memphis covers the Tennessee and Arkansas sides of the Mississippi River from river mile 725 (km 1167) to mile 740 (km 1191). ", "At 15 mi (24 km) long, it has 68 water fronted facilities, 37 of which are terminal facilities for moving products from shore to ship or vice versa. ", "It is 400 mi (644 km) downriver from St. Louis, Missouri and 600 mi (966 km) upriver from New Orleans.", "\n\nMississippi River bridges\n\nFour rail and highway bridges cross the Mississippi River at Memphis. ", "They are, in order of their opening: the Frisco Bridge, the Harahan Bridge, the Memphis & Arkansas Bridge and the Hernando de Soto Bridge. ", "The piers of the first three bridges had to be lined up for river navigation as they were built side-by-side at a narrow point in the river.", "\n\nFrisco Bridge\nThe Frisco Bridge (May 12, 1892) was the longest bridge in North America when it opened and was originally called the Great Bridge at Memphis. ", "This cantilever truss steel railroad bridge was built between 1888–1892. ", "It was designed by George S. Morison, who also designed the Taft Bridge in Washington, D.C..\n\nHarahan Bridge\nThe Harahan Bridge (July 14, 1916) is a trestle railroad bridge originally built with narrow, one-way wooden cantilevered roadways along the outsides so it could be used for cars. ", "In 1928, sparks from a train ignited and set fire to one of the wooden plank roads. ", "At present only trains use the Harahan Bridge, but a pedestrian walkway and bike path was completed in fall 2016.", "\n\nMemphis & Arkansas Bridge\n\nThe Memphis & Arkansas Bridge (December 17, 1949), carries Interstate 55 and has a pedestrian walkway. ", "The bridge was built between 1945–1949 and is the longest Warren truss- style bridge in the United States. ", "It is listed on the National Historic Register.", "\n\nHernando de Soto Bridge\nThe Hernando de Soto Bridge (August 2, 1973) with its steel arches carries Interstate 40. ", "In 1986, \"M\" shaped lights became part of the bridge and a Memphis landmark.", "\n\nThe Guinness Book of World Records lists the de Soto bridge for its unique structural \"letter\" shape. ", "In 2001 the mysterious disappearance and death of Harvard University biophysicist Don Wiley, whose abandoned car was found on the bridge, brought the Hernando de Soto Bridge national headlines.", "\n\nBridges overview\n\nReferences\n\n \nMemphis, Tennessee" ]
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0.006343
5
[ "---\nabstract: 'We present a new determination of the distance to M101, host of the type Ia SN 2011fe, based on the tip of the red giant branch method (TRGB). ", "Our determination is based on [*Hubble Space Telescope*]{} archival $F555W$ and $F814W$ images of nine fields within the galaxy. ", "Color-magnitude diagrams of arm-free regions in all fields show a prominent red giant branch (RGB). ", "We measure the $I$-band magnitudes of the TRGB, obtaining a mean value of $I_{\\rm TRGB}=25.28\\pm0.01$ (where the error is a standard error), using an edge-detection method. ", "We derive a weighted mean value of distance modulus $(m-M)_0=29.30\\pm0.01 ({\\rm random})\\pm0.12 ({\\rm systematic})$, corresponding to a linear distance of $7.24\\pm0.03\\pm0.40 $ Mpc. ", "While previous estimates for M101 show a large range (TRGB distances of $(m-M)_0=29.05$ to 29.42 and Cepheid distances of $(m-M)_0=29.04$ to 29.71), our measurements of the TRGB distances for nine fields show a small dispersion of only 0.02. ", "We combine our distance estimate and photometry in the literature to derive absolute peak magnitudes in optical and near-infrared bands of SN 2011fe. ", "Absolute maximum magnitudes of SN 2011fe are $\\sim0.2$ mag brighter in the optical band and much more in the NIR than the current calibrations of SNe Ia in the literature. ", "From the optical maximum magnitudes of SN 2011fe we obtain a value of the Hubble constant, $H_0=65.0\\pm0.5({\\rm random})\\pm5.7({\\rm systematic})$ [[km s$^{-1}$ Mpc$^{-1}$]{}]{}, slightly smaller than other recent determinations of $H_0$.'\nauthor:\n- Myung Gyoon Lee and In Sung Jang\ntitle: The Distance to M101 Hosting Type Ia SN 2011fe Based on the Tip of the Red Giant Branch \n---\n\nIntroduction\n============\n\nM101 (NGC 5457) is a well-known face-on spiral galaxy (SAB(rs)cd) in the M101 group. ", "In 2011 a new Type Ia supernova (SN Ia) 2011fe was discovered in this galaxy, being the fourth SN discovered in the same galaxy [@nug11; @liu12; @ric12]. ", "It is one of the nearest among the known galaxies hosting SNe Ia. SN 2011fe suffers little from interstellar extinction ($A_V\\sim 0.04$) and was discovered in less than one day after explosion[@nug11]. ", "Therefore it plays an important role for calibrating the absolute luminosity of SNe Ia as well as for studying the properties of SNe Ia including their progenitors [@rei05; @nug11; @tam12; @blo12; @rop12; @mat12].", "\n\nSurprisingly recent measurements of the distance to M101 show a large range, $(m-M)_0=29.04$ to 29.71 (@sha11 [@mat12; @vin12] and references therein). ", "Even the measurements based on two primary distance indicators, Cepheids and the tip of the red giant branch (TRGB) [@lee93], show a significant dispersion: $(m-M)_0=29.04$ to 29.71 for Cepheids [@kel96; @ken98; @ste98; @fre01; @mac01; @sah06; @sha11], and $(m-M)_0=29.05$ to 29.42 for the TRGB [@sak04; @riz07; @sha11]. ", "Note that one of the most recent estimates, @sha11, shows significant differences in both Cepheid and TRGB distances from previous ones. ", "Therefore the distance to M101 is still significantly uncertain in spite of its importance. ", "Consequently, a determination of the Hubble constant based solely on the photometry of SN 2011fe and previously-published distances can yield values ranging from 56 to 76 km s$^{-1}$ Mpc$^{-1}$ [@mat12]. ", "In this study we present a new determination of the distance to M101 using the TRGB, from the images for several fields within this galaxy available in the [*Hubble Space Telescope*]{} (HST) archive. ", "While previous studies to derive the TRGB distances to M101 were based on one or two fields, we used nine fields. ", "This allows us to estimate the M101 distance with much smaller statistical uncertainty than previous studies.", "\n\nData Reduction\n==============\n\nWe used $F555W$ and $F814W$ images of M101 taken with the HST/Advanced Camera for Surveys (ACS) (Proposal IDs: 9490, 9492, and 10918) and with the WFPC2 (Proposal ID: 8584). ", "Figure \\[fig\\_finder\\] displays a finding chart for M101, showing the HST fields used in this study (F1, F2, F3, F4, F5, and F6) and previous studies (S1 and S2 in @sha11 and S04 in @sak04). ", "Note that the S04 field is isolated in the outskirts of the disk, while S1 and S2 are much closer to the center than the other fields. ", "Two fields used in previous Cepheid studies [@kel96; @ken98] are denoted by ’outer’ and ’inner’, respectively.", "\n\nWe derived instrumental magnitudes of point sources in the ACS images using the IRAF/DAOPHOT package that is designed for point spread function (PSF) fitting photometry [@ste94]. ", "We used 2-$\\sigma$ as the detection threshold, and derived the PSFs using isolated bright stars in the images. ", "We derived aperture corrections using a large aperture with radius of $1\\arcsec$ for several isolated bright stars in the images. ", "The uncertainties associated with aperture correction are on average 0.02 mag for both filters. ", "We transformed the instrumental magnitudes into the standard Johnson-Cousins $VI$ magnitudes, following equations (1) and (12) for observed magnitudes of @sir05. ", "In the case of WFPC2 images we used Dolphot (http://americano.dolphinsim.com/dolphot/). ", "The uncertainties associated with the photometric transformations are on average 0.02 mag.", "\n\nResults\n=======\n\nColor-magnitude Diagrams of Resolved Stars\n------------------------------------------\n\nM101 is an almost face-on galaxy (inclination angle = 17 deg [@zar90]) and all HST fields available in the archive are overlapped with the disk of the galaxy so that they must include a mixture of disk stars and old halo stars. ", "To reduce the fraction of young disk stars as much as possible in constructing the color-magnitude diagrams (CMDs) for each field, we chose the stars located away from the spiral arms of star-forming regions in each field. ", "Thus selected regions in each field are marked by the hatched region in Figure 1. ", "Foreground reddening toward M101 is known to be very small, $E(B-V)=0.008$ [@sch98; @sch11]. ", "Corresponding values are $A_I=0.013$ and $E(V-I)=0.010$. Internal reddening for red giants in the arm-free regions of this face-on galaxy is expected to be negligible so that it is not corrected in the following analysis.", "\n\nFigure \\[fig\\_cmd\\] displays the CMDs for the stars in the selected regions of F1, F2, F3, F4, F5, F6, (S1 + S2), and S04 fields. ", "The CMDs for all fields show a prominent red giant branch (RGB) as well as weaker asymptotic giant branch (AGB), massive giants, and blue main sequence. ", "These RGBs are useful for estimating the magnitude of the TRGB and the distance to M101.", "\n\nDistance Estimation\n-------------------\n\nWe determined the distance to the target fields using the TRGB method, which is known to be an excellent distance indicator for resolved stellar systems [@lee93; @sak96; @men02; @bel08; @mou10; @sal11]. ", "First we derived the $I$-band luminosity functions of the red giants in each field using the stars inside the boundary marked in Figure \\[fig\\_cmd\\], and plotted them in Figure \\[fig\\_ilf\\]. ", "Figure \\[fig\\_ilf\\] shows that there appears to be a sudden jump at $I \\approx 25.3$ mag in each field, which corresponds to the TRGB.", "\n\nUsing the edge-detecting algorithm [@sak96; @men02; @mou10], we determined the TRGB magnitude more quantitatively. ", "We calculated an edge-detection response function $E(m)$ ($= \\Phi (m + \\sigma_m ) - \\Phi (m - \\sigma_m ) $ where $\\Phi (m)$ is the luminosity function of magnitude $m$ and $\\sigma_m$ is the mean photometric error within a bin of $\\pm0.05$ mag about magnitude $m$), as shown in Figure \\[fig\\_ilf\\]. ", "The errors for the TRGB magnitudes were determined using bootstrap resampling method with one million simulations. ", "In each simulation we resampled randomly the RGB sample with replacement to make a new sample of the same size. ", "We estimated the TRGB magnitude for each simulation using the same procedure, and derived the standard deviation of the estimated TRGB magnitudes. ", "The median color of the TRGB is derived from the colors of the bright red giants close to the TRGB. ", "We used the recent calibration for the absolute magnitude of the TRGB given in @riz07: $M_{{\\rm I,TRGB}} = - 4.05(\\pm0.02) + 0.217(\\pm0.01)( (V-I)_0 -1.6)$ (where $(V-I)_0$ is a reddening corrected color of the TRGB), which is very similar to that given in @tam08. ", "Then we calculate the distance modulus using $(m-M)_0 = I_{\\rm 0, TRGB} - M_{\\rm I, TRGB}$.\n\nWe also derived the distance using the composite magnitude $T$ for the RGB introduced in @mad09: $T = I_{0, TRGB} - 0.20 [(V-I)_{0} -1.5)]$ and $(m-M)_0 = T - M_{I,TRGB}$ $= I_{0, TRGB} - 0.20 (V-I)_{0} +4.35$. This calibration is based on the absolute TRGB magnitude of $M_{I,TRGB} = - 4.05$ for $(V-I)_0=1.5$, similar to the calibration in @riz07.", "\n\nTable 1 lists a summary of the distance determination for the fields in M101 derived in this study, which is also shown in Figure 4. ", "Table 1 includes $I$-band magnitudes of the TRGB, $T$ magnitudes of the RGB, $(V-I)$ color of the RGB (before foreground reddening correction), absolute $I$-band magnitudes of the TRGB, and distance moduli from $I$-band magnitudes and $T$ magnitudes. ", "Remarkably the $I$-band magnitudes of the TRGB derived for all nine fields show a small range from 25.24 (F2) to 25.30 (F5, S1, S2 and S04). ", "A weighted mean value is derived to be $I_{\\rm TRGB}=25.28\\pm0.01$ (where the error is a standard error) with a standard deviation of only 0.02. ", "Similarly the distance moduli for all fields show a small range from $(m-M)_0=29.26\\pm0.03$ (F4) to $29.33\\pm0.02$ (F5). ", "We derive a weighted mean value of distance modulus $(m-M)_0=29.30\\pm0.01$ where 0.01 is a random error, corresponding to a linear distance of $7.24\\pm0.03 $ Mpc. ", "Its systematic error is estimated to be 0.12, considering (a) the TRGB calibration error of 0.12 [@bel01; @bel04; @mag08], (b) the aperture correction error of 0.02, (c) and the standard calibration error of 0.02 for ACS/WFC [@sir05] and 0.07 for WFPC2 [@ste98a]. ", "Similar results are obtained from the $T$ magnitude method, $(m-M)_0=29.26\\pm0.01$, but with three times larger standard deviation (0.07). ", "We adopt the results from the traditional $I$-band magnitude method, as the distance to M101, which shows a smaller scatter than the $T$ magnitude results.", "\n\nDiscussion\n==========\n\nComparison with Previous Distance Estimates\n-------------------------------------------\n\nWe compare our estimates for the distance to M101 with those in the literature based on TRGB, Cepheids, and SN Ia in Figure \\[fig\\_comp\\]. ", "Recently @sha11 derived a TRGB distance from the analysis of S1 and S2 fields, $(m-M)_0=29.05 \\pm0.06 ({\\rm random}) \\pm0.12 ({\\rm systematic})$. This value is 0.3 to 0.4 mag smaller than the previous TRGB distance estimates by @sak04 and @riz07. ", "The TRGB magnitudes for M101 derived in the previous studies are $I_{0,\\rm TRGB} = 25.40\\pm0.04$ in @sak04, $25.29\\pm0.08$ in @riz07, and $T = 25.00\\pm0.06$ in @sha11. ", "Therefore the large difference among the previous TRGB distance estimates are mainly due to the difference in the measured TRGB magnitudes. ", "Our mean value of the TRGB magnitudes (after foreground extinction correction), $I_{0,\\rm TRGB}=25.27\\pm0.01$ (and $T_{\\rm RGB}=25.33\\pm0.03$ for (S1+S2) fields) is close to the value in @riz07, 0.13 mag brighter than the value in @sak04, and 0.33 mag fainter than the value in @sha11. ", "Our values for the S04 field ($I_{0,\\rm TRGB}=25.29\\pm0.03$) and for the sum of S1 and S2 fields ($I_{0,\\rm TRGB}=25.29\\pm0.04$) are similar to the mean value of nine fields. ", "The large difference in the TRGB magnitudes between this study and @sha11 is probably due to contamination by disk stars in the sample used by the latter.", "\n\nThe Cepheid distance estimates for M101 derived in the previous studies show a large range. ", "Two HST fields in M101 (inner field and outer field, as shown Figure 1) were used for Cepheids in the previous studies. ", "They show on average $\\sim 0.2$ smaller values for the inner field [@ste98; @sah06; @ken98; @mac01; @sha11] than those for the outer field [@kel96; @ken98; @mac01; @sah06]. ", "This difference between the inner and outer fields may be considered to be mainly due to metallicity gradient in the galaxy disk. ", "However, the distance modulus difference shows a large range from almost zero [@sah06] to ∼ 0.4 mag [@mac01], depending on the authors. ", "This difference has been explained. ", "@sah06 adopted a metallicity correction very similar to @fre01, which led them to Cepheid distances of 29.16 for the inner field and 29.18 for the outer field. ", "These compare well to the $H_0$ Key Project final value of $29.13\\pm0.11$ mag [@fre01]. ", "@mac01 carried out artificial star tests and showed that their NICMOS photometry for the inner field was by $\\sim$0.2 mag affected by blending. ", "Cepheid distance estimates show a large scatter (of ∼ 0.3 mag) even for the outer field where blending effect is less severe, depending on the authors. ", "The distance estimates by @fre01 [@sak04; @sah06] show a good agreement among them, but they are $\\sim$0.2 mag shorter than those by @kel96 [@ken98; @mac01]. ", "The cause for this scatter needs to be investigated.", "\n\nIn contrast, our measurements of the TRGB magnitude for nine fields show a remarkably small dispersion. ", "Note that our measurements show an excellent agreement among independent photometry (for example, between DAOPHOT photometry of ACS images and DOLPHOT photometry of WFPC2 images, among three different sets of HST images (F fields, S1 and S2 fields, and S04 fields), and among all nine fields).", "\n\nThe Absolute Calibration of SNe Ia and the Hubble Constant\n----------------------------------------------------------\n\nWe can use the distance measurement for M101 to check the calibration of SN Ia and to derive a value for the Hubble constant. ", "Using two SN Ia optical light curve fitting methods with $BVRI$ photometry of SN 2011fe, @vin12 obtained two estimates for the distance to M101 (assuming $H_0 = 73$ km s$^{-1}$ Mpc $^{-1}$): $(m-M)_0 = 29.21\\pm0.07$ from the MLCS2k2 method [@jha07] and $(m-M)_0 = 29.05\\pm0.08$ from the SALT2 method [@guy07]. ", "They concluded that the difference between these two estimates is considered to be due to difference in the zero point calibration of the fiducial SN peak magnitude in the two methods. ", "Our result is closer to the value from the MLCS2k2 method [@jha07], indicating that the calibration of the MLCS2k2 method is closer to the TRGB calibration, for the adopted $H_0 = 73$ km s$^{-1}$ Mpc $^{-1}$.\n\n@ric12 presented optical maximum magnitudes of SN 2011fe: $B_{\\rm max} = 10.00\\pm0.02$, $V_{\\rm max} = 9.99\\pm0.01$, $R_{\\rm max} = 9.99\\pm0.02$ and $I_{\\rm max} = 10.21 \\pm0.03$, and derived absolute magnitudes of SN 2011fe adopting a distance modulus of $(m-M)_0 = 29.10\\pm0.15$. They derived also similar values considering the decline rate of $\\Delta m_{15} (B) = 1.21\\pm0.03$. Adopting our distance measurement, we derive absolute magnitudes of SN 2011fe that are $\\sim$0.2 mag brighter than those in @ric12: $M_{B, {\\rm max}} = -19.41\\pm0.13$, $M_{V, {\\rm max}} = -19.39\\pm0.13$, and $M_{R, {\\rm max}} = -19.38\\pm0.13$, and $M_{I, {\\rm max}} = -19.14\\pm0.13$. ($M_{B, {\\rm max}} = -19.45\\pm0.13$, $M_{V, {\\rm max}} = -19.38\\pm0.13$, and $M_{R, {\\rm max}} = -19.39\\pm0.13$, and $M_{I, {\\rm max}} = -19.12\\pm0.13$ after the decline rate correction). ", "The derived value of $M_{V, {\\rm max}} = -19.38 \\pm 0.13$ is between of the values derived from nearby SNe Ia in the previous studies: recent values in @rie11 ($M_{V,{\\rm max}} = -19.15\\pm0.07$) and old values in @gib00 ($M_{V,{\\rm max}}=-19.46\\pm0.05$) that are similar to those in @san06. ", "Near-infrared (NIR) photometry of SN Ia is potentially a very promising tool for cosmology [@kat12; @bar12]. ", "However, recent calibrations of the NIR absolute magnitudes of SN Ia show large differences ( $\\sim$ 0.4 mag) [@woo08; @fol10; @bur11; @man09; @man11; @kat12], as summarized in @mat12. ", "Our distance measurement for M101 is very useful for calibrating these NIR zero points of the SN Ia templates. ", "@mat12 derived a large range of distance estimates from $JHK_S$ photometry of SN 2011fe: $(m-M)_0 = 28.86$ to 29.17, depending on the adopted calibration. ", "These values are much smaller than our distance measurement. ", "@mat12 presented $JHK_s$ maximum magnitudes in each band for SN 2011fe: $J_{\\rm max} = 10.51\\pm0.04$, $H_{\\rm max} = 10.75\\pm0.04$, and $K_{s,\\rm max} = 10.64\\pm0.04$, and $JHK_s$ magnitudes at the $B$-band maximum time for SN 2011fe: $J_{B_{\\rm max}} = 10.62\\pm0.04$, $H_{B_{\\rm max}} = 10.85\\pm0.04$, and $K_{s,B_{\\rm max}} = 10.68\\pm0.05$. ($A_K=0.01$ is ignored here, as in @mat12 (see their Fig. ", "3)).", "\n\nFrom these values with our distance estimate we derive the NIR absolute magnitudes for SN 2011fe: $M_{J,{\\rm max}} = -18.79\\pm0.14$, $M_{H,{\\rm max}} = -18.55\\pm0.14$, and $M_{K_s, {\\rm max}} = -18.66 \\pm0.13$ ($M_{J,{B_{\\rm max}}} = -18.68\\pm0.14$, $M_{H,{B_{\\rm max}}} = -18.45\\pm0.14$, and $M_{K_s, {B_{\\rm max}}} = -18.62 \\pm0.14$ for the $B$-band maximum time). ", "These values are $\\sim$0.2 mag or more brighter than recent calibration of the NIR magnitudes for SN Ia available in the literature [@woo08; @fol10; @bur11; @man09; @man11; @kat12]. ", "If we use absolute magnitudes of SN 2011fe derived in this study, we obtain a value for the Hubble constant using the equation log $H_0 = 0.2 M_\\lambda ({\\rm max}) + C_\\lambda +5$ (where $C_B=0.693\\pm0.004$, $C_V=0.688\\pm0.004$, and $C_I=0.637\\pm0.004$) [@rei05], $H_0 = 65.0 \\pm0.5{\\rm (random)} \\pm5.7 {\\rm (systematic)}$ [[km s$^{-1}$ Mpc$^{-1}$]{}]{} (we included the internal luminosity dispersion of SNe Ia of 0.14 mag (@tam12) for calculating the systematic error). ", "This value is similar to that given in @tam12 based on six SNe Ia including SN 2011fe, $H_0 = 64.0 \\pm1.6 \\pm2.0$ [[km s$^{-1}$ Mpc$^{-1}$]{}]{}, but smaller than other recent determinations [@rie11; @fre12], $H_0 = 74 \\pm3 $ km s$^{-1}$ Mpc$^{-1}$. This implies three possibilities: (a) that the optical maximum magnitudes of SN 2011fe may be $\\sim0.2$ mag brighter than typical SNe Ia, (b) that the recent calibration of optical maximum magnitudes of SN Ia may be $\\sim$0.2 mag fainter, or (c) that the value for the Hubble constant may be somewhat lower than the values derived recently in other studies.", "\n\nSummary\n=======\n\nWe present a new determination of the distance to M101, host of the Type Ia SN 2011fe, using the tip of the red giant branch method (TRGB) from $F555W$ and $F814W$ images of nine fields within this galaxy in the Hubble Space Telescope archive. ", "Primary results are as follows.", "\n\n- Color-magnitude diagrams of arm-free regions in all fields show a prominent RGB.", "\n\n- We measured the $I$-band magnitudes of the TRGB, obtaining a mean value of $I_{\\rm TRGB}=25.28\\pm0.01$ with a standard deviation of only 0.02, using an edge-detection method. ", "From this we derive a weighted mean value of distance modulus $(m-M)_0=29.30\\pm0.01({\\rm random})$, corresponding to a linear distance of $7.24\\pm0.03 $ Mpc. ", "Its systematic error is estimated to be 0.12. ", "Our measurements of the TRGB distances for nine fields show a small dispersion of only 0.02, much smaller than the previous estimates.", "\n\n- With this distance value we derive the optical and NIR absolute maximum magnitudes of SN 2011fe (at the maximum of each band and at the $B$-band maximum time). ", "Absolute magnitudes of SN 2011fe are $\\sim$0.2 mag brighter in the optical band and much more in the NIR than the recent calibrations of SN Ia in the literature.", "\n\n- From the optical magnitudes of SN 2011fe and our distance measurement for M101 we obtain a value of the Hubble constant, $H_0=65.0 \\pm0.5({\\rm random}) \\pm5.7({\\rm systematic})$ [[km s$^{-1}$ Mpc$^{-1}$]{}]{}, somewhat smaller than other recent determinations @rie11 [@fre12]. ", "This implies (a) that optical maximum magnitudes of SN 2011fe may be $\\sim$0.2 mag brighter than typical SNe Ia, (b) that the recent calibration of optical maximum magnitudes of SN Ia may be $\\sim0.2$ mag fainter, or (c) that the value for the Hubble constant may be somewhat lower than other recent determinations.", "\n\nThe authors are grateful to the anonymous referee for his/her comments that improved the original manuscript. ", "This is supported in part by the Mid-career Researcher Program through an NRF grant funded by the MEST (No.2010-0013875).", "\n\nBarone-Nugent, R. L., Lidman, C., Wyithe, J. S. B., et al.", " 2012, , 425, 1007 Bellazzini, M., Ferraro, F. R., & Pancino, E. 2001, , 556, 635 Bellazzini, M., Ferraro, F. R., Sollima, A., Pancino, E., & Origlia, L. 2004, , 424, 199 Bellazzini, M. 2008, , 79, 440 Bloom, J. S., Kasen, D., Shen, K. J., et al.", " 2012, , 744, L17 Burns, C. R., Stritzinger, M., Phillips, M. M., et al.", " 2011, , 141, 19 Folatelli, G., Phillips, M. M., Burns, C. R., et al.", " 2010, , 139, 120 Freedman, W. L., Madore, B. F., Gibson, B. K., et al.", " 2001, , 553, 47 Freedman, W. L., & Madore, B. F. 2010, , 48, 673 Freedman, W. L., Madore, B. F., Scowcroft, V., et al.", " 2012, , 758, 24 Gibson, B. K., Stetson, P. B., Freedman, W. L., et al. 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M., & Elston, R. 1990, , 99, 1108\n\n[rccccccccc]{}\n\nF1 & $R_{GC}\\ge7'.5$ & $25.27\\pm0.03$ & $25.19\\pm0.02$ & $1.54\\pm0.04$ & $-4.065\\pm0.009$ & $29.32\\pm0.03$ & $29.24\\pm0.02$\\\nF2 & $R_{GC}\\ge6'.5$ & $25.24\\pm0.04$ & $25.15\\pm0.03$ & $1.60\\pm0.05$ & $-4.052\\pm0.011$ & $29.28\\pm0.04$ & $29.20\\pm0.03$\\\nF3 & $R_{GC}\\ge5'.9$, Dec $\\ge 54\\,^{\\circ}.4 $ & $25.27\\pm0.03$ & $25.15\\pm0.04$ & $1.66\\pm0.05$ & $-4.039\\pm0.011$ & $29.30\\pm0.03$ & $29.20\\pm0.04$\\\nF4 & $7'.3\\le R_{GC}<8'.3$, R.A. $< 210\\,^{\\circ}.73$ & $25.25\\pm0.03$ & $25.24\\pm0.03$ & $1.72\\pm0.06$ & $-4.026\\pm0.013$ & $29.26\\pm0.03$ & $29.29\\pm0.03$\\\nF5 & $R_{GC}\\ge10'.1$ & $25.30\\pm0.02$ & $25.17\\pm0.02$ & $1.65\\pm0.05$ & $-4.041\\pm0.011$ & $29.33\\pm0.02$ & $29.22\\pm0.02$\\\nF6 & $R_{GC}\\ge8'.1$ & $25.26\\pm0.03$ & $25.26\\pm0.04$ & $1.71\\pm0.05$ & $-4.028\\pm0.011$ & $29.28\\pm0.03$ & $29.31\\pm0.04$\\\nS1 & $R_{GC}\\ge4'.75$ & $25.30\\pm0.04$ & $25.29\\pm0.03$ & $1.81\\pm0.04$ & $-4.007\\pm0.009$ & $29.29\\pm0.04$ & $29.34\\pm0.03$\\\nS2 & $R_{GC}\\ge4'.75$ & $25.30\\pm0.04$ & $25.33\\pm0.03$ & $1.91\\pm0.03$ & $-3.985\\pm0.007$ & $29.27\\pm0.04$ & $29.38\\pm0.03$\\\nS1+2 & $R_{GC}\\ge4'.75$ & $25.30\\pm0.04$ & $25.33\\pm0.03$ & $1.87\\pm0.05$ & $-3.994\\pm0.011$ & $29.28\\pm0.04$ & $29.38\\pm0.03$\\\nS04 & $R_{GC}\\ge8'.5$ & $25.30\\pm0.03$ & $25.24\\pm0.03$ & $1.81\\pm0.05$ & $-4.007\\pm0.011$ & $29.29\\pm0.03$ & $29.29\\pm0.03$\\\n& $25.28\\pm0.01$ & $25.21\\pm0.01$& $1.68\\pm0.02$ & $-4.034\\pm0.004$ & $29.30\\pm0.01$ & $29.26\\pm0.01$\\\n\n![", "Location of the HST fields marked on the gray scale map of a 21$'$ $\\times$ 21$'$ SDSS i-band image of M101. ", "F1, F2, F3, F4, F5, and F6 represent the fields used in this study, S1 and S2 used in @sha11, and S04 in @sak04. ", "Two fields used in previous Cepheid studies [@kel96; @ken98] are labeled by ’outer’ and ’inner’, respectively. ", "Only the hatched regions were used in the analysis. ", "North is up and east to the left. []{", "data-label=\"fig_finder\"}](fig1.eps)\n\n![", "$I-(V-I)$ color-magnitude diagrams of the stars in the arm-free regions in each field of M101. ", "Note the the prominent RGBs are seen as well as other weaker features. ", "Boxes represent the boundary of the red giants used for deriving the luminosity functions of the red giant stars in each field. ", "Arrows represent the positions of the TRGB. []{", "data-label=\"fig_cmd\"}](fig2.eps)\n\n![", "$I$-band luminosity functions of the red giants in each field of M101 (solid line histograms). ", "Dashed lines represent edge-detection responses, and arrows represent the positions of the TRGB. []{", "data-label=\"fig_ilf\"}](fig3.eps)\n\n![", "A comparison of the distance measurements for M101 based on the TRGB (open symbols), Cepheids (filled symbols), and SN 2011fe (bars without any symbol) versus fields of study: F1-F6 in this study, S1 and 2 in @sha11, S04 in @sak04, inner and outer fields for Cepheids, and others. ", "The long horizontal arrow represents the weighted mean value of the TRGB distance estimates derived in this study. ", "The bar at the right end represents the $H_0$ value depending on the M101 distance, based on the relation in @rei05.[]{data-label=\"fig_comp\"}](fig4.eps)\n" ]
{ "pile_set_name": "ArXiv" }
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0.012039
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[ "Esports at the 2018 Asian Games – Hearthstone tournament\n\nThe Hearthstone tournament at the 2018 Asian Games was an eSports demonstration event that was contested on 31 August 2018. ", "It was won by Lo Tsz Kin (Kin0531) of Hong Kong.", "\n\nQualification\nHearthstone qualification were determined through online matches. ", "Indonesia as hosts automatically qualifies.", "\n\nRegional qualification\nA round robin format was used for the qualification tournaments.", "\n\nEast Asia\n\n Japan won the head to head against China\n\nSoutheast Asia\n\nSouth Asia\n\nCentral Asia\n\nWest Asia\n\nPlayers\nThe following eight players participated in the Hearthstone tournament.", "\n\nTournament\nThe format used for this event was best of five, single elimination.", "\n\nResults\n\nReferences\n\nHearthstone\nCategory:Hearthstone competitions" ]
{ "pile_set_name": "Wikipedia (en)" }
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[ "The Canton Charge pulled off a trade Thursday and moved up in the draft.", "\n\nOfficially, the Cavaliers’ G League affiliate sent guard Kobi Simmons and the 14th overall pick in the G League draft to the Greensboro Swarm for guard Jaylen Barford and the 12th overall pick.", "\n\n“We are excited to acquire the rights of a dynamic scorer and athlete like Jaylen, plus move up a couple slots in the draft as well,” Charge general manager Brendon Yu said. “", "We wish Kobi the best as he continues his basketball journey.”", "\n\nSimmons actually agreed to a training camp deal with the Hornets a couple weeks ago. ", "With Terry Rozier and Devonte’ Graham as the only point guards on the roster, Simmons may have a shot to make the team.", "\n\nThe 6-foot-4 Simmons appeared in one game with the Cavs last season and 32 with the Memphis Grizzlies as a rookie in 2017-18.", "\n\nMeanwhile, Barford is 6-3 and attended training camp with the Hornets last season. ", "He averaged 17.7 points on 44 percent shooting in 47 games with the Swarm." ]
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0.014321
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[ "Q:\n\nFramework for acceptance testing involving text files with regexes\n\nI have created a software package that produces a directory full of results. ", "I would like to test the results from some standard input files. ", "The directories should be somewhat similar on each run except for a limited number of things that change: traces of the current date/time, a run-specific UUID, current Subversion revision number. ", "This is complicated by the fact that sometimes these variables are inserted into the body of text files, and sometimes into their file names. ", "And sometimes the text files have been gzip-compressed. ", "This all complicates using diff to just compare the directories.", "\nIdeally I would like to be able to take one \"golden\" run of the application, edit the output files to replace the variables with some sort of regex syntax, and run some application to compare the directories, accepting things that match the regex syntax. ", "Is there a testing framework that could do this for me easily? ", "Best would be if it had a command-line interface, second best would be a Python interface. ", "If not, I guess I will probably try to roll something up myself.", "\n\nA:\n\nI sounds like you should take a look at TextTest. ", "I haven't used it personally but based on what I know it ought to fit into your needs pretty well.", "\n\n" ]
{ "pile_set_name": "StackExchange" }
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[ "7th July 2017 Current Affairs Quiz\n\n7th July 2017 Current Affairs Quiz\n\n1. ", "The Election Commission (EC) has decided to mandatorily tally paper trail slips with the results of EVMs in ____ per cent of polling stations in each assembly seat, for all state\nand Lok Sabha elections.", "\n\nA. 3\n\nB. 4\n\nC. 6\n\nD. 5\n\nLoading...\n\n2. ", "India on July 5, 2017 signed how many agreements with Israel?", "\n\nA. 7\n\nB. 6\n\nC. 5\n\nD. 8\n\nLoading...\n\n3. ", "What is the full form of 'MERIT app?", "\n\nA. Merit Order Despatch of Electricity for Rejuvenation of Income and Transparency\n\nB. Meritorious Order Despatch of Electricity for Rejuvenation of Income and Transparency\n\nC. Management Order Despatch of Electricity for Rejuvenation of Income and Transparency\n\nD. Mutual Order Despatch of Electricity for Rejuvenation of Income and Transparency\n\nLoading...\n\n4. ", "Van Mahotsav celebrations, that is celebrated in the first week of July every year is celebrated in India since\n\nA. 1952\n\nB. 1950\n\nC. 1951\n\nD. 1953\n\nLoading...\n\n5. ", "Which country Ambassador is Pradeep Kumar Rawat?", "\n\nA. India\n\nB. Indonesia\n\nC. Iran\n\nD. England\n\nLoading...\n\n6. ", "How many banks tied up with the Employment Provident Fund Organisation (EPFO))?", "\n\nA. 5\n\nB. 4\n\nC. 3\n\nD. 2\n\nLoading...\n\n7. ", "Which of the following state governments has launched ‘Elevate 100’ scheme to identify and nurture 100 most innovative start-ups in the state?", "\n\nA. Madhya Pradesh\n\nB. Maharashtra\n\nC. Karnataka\n\nD. Telangana\n\nLoading...\n\n8. ", "How much amount of fund has been allotted by the Karnataka government under ‘Elevate 100’ scheme to identify and nurture 100 most innovative start-ups in the state?", "\n\nA. Rs 600 crore\n\nB. Rs 700 crore\n\nC. Rs 500 crore\n\nD. Rs 400 crore\n\nLoading...\n\n9. ", "Which among the following village was adopted by Prime Minister Modi under Sansad Adarsh Gram?", "\n\nA. Kakrahia\n\nB. Jayapur\n\nC. Nagpur\n\nD. Anantapur\n\nLoading...\n\n10. ", "About 97% of the total outstanding debt of all State discoms has been covered under UDAY (Ujwal DISCOM Assurance YojanA. and 26 states & 1 UT which have joined\nthe UDAY scheme accounts for a total outstanding debt of __ crore.", "\n\nA. B.51 lakh\n\nB. B.72 lakh\n\nC. C.82 lakh\n\nD. C.91 lakh\n\nLoading...\n\n11. ", "Which Indian city is hosting the International Conference on sports “CII ScoreCard 2017”?", "\n\nA. New Delhi\n\nB. Pune\n\nC. Jaipur\n\nD. Lucknow\n\nLoading...\n\n12. ", "Which Indian athlete was the flag bearer for the Indian contingent in the 22nd Asian Athletics Championship (AAC) -2017?", "\n\nA. Jitu Rai\n\nB. Tintu Luka\n\nC. Srabani Nanda\n\nD. Dipa Karmakar\n\nLoading...\n\n13. ______ ", "sets up research base to counter illegal drones\n\nA. China\n\nB. Israel\n\nC. Italy\n\nD. Japan\n\nLoading...\n\n14. __________", "plans to launch smart speaker powered by Bixby\n\nA. Nokia\n\nB. Microsoft\n\nC. Sony\n\nD. Samsung\n\nLoading...\n\n15. ", "In which state free GST facilitation centers will be set up?", "\n\nA. Goa\n\nB. Gujarat\n\nC. Haryana\n\nD. Punjab\n\nLoading...\n\n16. ", "In which city airport India’s tallest ATC tower to be operational by December?", "\n\nA. Chennai Airport\n\nB. Delhi Airport\n\nC. Mumbai Airport\n\nD. Kolkata Airport\n\nLoading...\n\n17. ", "Which state has been ranked at the bottom most position in public affairs index (PAI) in governance in States this year prepared by think-tank Public Affairs Centre (PAC),\nBengaluru?" ]
{ "pile_set_name": "Pile-CC" }
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0.008733
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[ "e of 397*f**4/12 - 18*f. ", "Is j(1) a prime number?", "\nTrue\nLet d(s) = -25*s + 1. ", "Let f be d(-5). ", "Let x = f + -69. ", "Is x prime?", "\nFalse\nLet v = 914 + 523. ", "Is v composite?", "\nTrue\nLet s(y) = 17*y**3 - 9*y**2 + 6*y + 5. ", "Let j(m) = 35*m**3 - 19*m**2 + 13*m + 10. ", "Let a(b) = 6*j(b) - 13*s(b). ", "Is a(-3) prime?", "\nFalse\nLet f(t) = -170*t**3 + 3*t**2 + 5*t + 3. ", "Let p be f(-2). ", "Is (3 + p/6)*4 composite?", "\nTrue\nSuppose -2*g + 0*g - 2*z = 22, 0 = g - z + 11. ", "Let l be (-12 + 7)*g/(-1). ", "Let m = l - -166. ", "Is m a composite number?", "\nTrue\nSuppose -4*q + 24 = 4*r, 0*q = 4*q + r - 18. ", "Let j be (-4 - q)/(-4) + 4. ", "Suppose j*t = 2106 - 204. ", "Is t a composite number?", "\nFalse\nSuppose 44036 + 28417 = 3*t. ", "Is t a composite number?", "\nFalse\nLet b = -29 - -78. ", "Let v(a) = 10*a**2 + 6*a - 8. ", "Let x be v(-5). ", "Let t = x - b. Is t a prime number?", "\nTrue\nLet v(c) be the first derivative of -43*c**2/2 - 6*c + 8. ", "Is v(-9) a prime number?", "\nFalse\nIs 6/21 + (-51336)/(-56) prime?", "\nFalse\nLet c(i) = -21*i - 22. ", "Let s be c(-10). ", "Suppose -8*l + 6*l = -s. ", "Is l prime?", "\nFalse\nLet w be (-60)/(-9)*-9*(-5)/(-30). ", "Let f(a) = 132*a - 59. ", "Let k(x) = 33*x - 15. ", "Let u(z) = 2*f(z) - 9*k(z). ", "Is u(w) composite?", "\nFalse\nLet c(t) = -4*t**3 + t + 1. ", "Let f be c(-1). ", "Suppose 0 = f*u - s + 1, 5*s - 28 = -3*u - 0*u. ", "Is (-9 + 6)/(u/(-7)) prime?", "\nFalse\nSuppose -3*l - 3 = -24. ", "Suppose -l*i - 609 = -10*i. ", "Is i a composite number?", "\nTrue\nLet u(s) = -506*s - 103. ", "Is u(-12) prime?", "\nFalse\nLet y be (-4)/4 + -13689 - -1. ", "Is y/(-65) - 4/(-10) a composite number?", "\nFalse\nSuppose -2*f - 2*f + 1580 = -5*h, 5*f = -3*h - 985. ", "Let r = h - -535. ", "Is r composite?", "\nTrue\nLet o(b) = -6 + 1785*b - 93*b + 7. ", "Is o(1) a composite number?", "\nFalse\nLet o(f) = 5*f**2 - 10*f + 2. ", "Let n(y) = -6*y**2 + 9*y - 2. ", "Let w(c) = -4*n(c) - 3*o(c). ", "Is w(-5) composite?", "\nFalse\nLet b = -70 + -283. ", "Suppose 4*n = 3224 - 584. ", "Let y = n + b. Is y a composite number?", "\nFalse\nSuppose -2*u = -7699 + 2177. ", "Is u a prime number?", "\nFalse\nLet m = -1396 - -2087. ", "Is m prime?", "\nTrue\nLet z(r) = -51*r**3 - 5*r**2 - 3*r - 1. ", "Let h be z(-3). ", "Let u = -709 + h. Is u prime?", "\nTrue\nLet v = -59 - -9. ", "Let i be 40/v - 6382/10. ", "Let o = 1190 + i. Is o a composite number?", "\nTrue\nLet n be (1*-1 + 30)*(118 - 117). ", "Let f(a) = 2*a**2 - 40*a - 73. ", "Is f(n) a composite number?", "\nFalse\nLet x(j) = 10*j**2 + 2*j + 9. ", "Let c(z) = -z**2 - 1. ", "Let q(m) = 3*c(m) + x(m). ", "Let w be q(-4). ", "Let l = w + -73. ", "Is l a composite number?", "\nFalse\nIs (2/(-3))/((-2)/59217) a composite number?", "\nFalse\nLet r = -18 + 11. ", "Let b = -5 - r. Suppose -3*d = -4*h + 151, b*h + 0*h - 53 = -3*d. ", "Is h prime?", "\nFalse\nLet k = -7 + 7. ", "Suppose z - 233 = -k. ", "Is z composite?", "\nFalse\nLet c be 48/(-22) - (-8)/44. ", "Is (-56562)/(-42) + c/(-7) a prime number?", "\nFalse\nLet t(m) = m**3 + 14*m**2 + 14*m + 5. ", "Let o be t(-13). ", "Let p(s) = 14*s**2 - 10*s + 1. ", "Is p(o) prime?", "\nTrue\nLet h = -17 + 17. ", "Suppose h*r - 388 = -4*r. ", "Is r a prime number?", "\nTrue\nLet t = 1519 + -888. ", "Is t a composite number?", "\nFalse\nLet n be (-7)/((-21)/3420)*(4 + -3). ", "Suppose 3421 = 3*p - b - b, 0 = -p + b + n. Is p a composite number?", "\nTrue\nSuppose 0 = v - 2*c + 12 - 1, 0 = 5*v - 5*c + 35. ", "Let u be 4 - (10076/(-12) - (-2)/(-6)). ", "Is v/(-2)*u/6 composite?", "\nFalse\nSuppose 17858 = 7*t - 29511. ", "Is t prime?", "\nFalse\nLet z = 24 - 22. ", "Let p = 263 + -151. ", "Suppose 5*y - 2*q = 445, 4*y - z*q - 244 = p. Is y a composite number?", "\nFalse\nLet k(w) = w**2 + 5*w + 33. ", "Let f(v) = 7*v + 29. ", "Let a(o) = -4*f(o) + 3*k(o). ", "Let m(t) = -t**2 - 8*t. ", "Let x be m(-6). ", "Is a(x) a prime number?", "\nFalse\nIs 90/(-72) - 143643/(-12) a prime number?", "\nTrue\nLet t = -8864 + 14091. ", "Is t a composite number?", "\nFalse\nLet u = -4605 + 17192. ", "Is u prime?", "\nFalse\nLet o(j) = 5*j**2 - 37*j - 43. ", "Is o(-13) prime?", "\nTrue\nSuppose 8 = -4*h, -4*s = -5*h - 89 - 137. ", "Suppose -3*k - 3 = -4*k. ", "Let p = s + k. Is p a composite number?", "\nTrue\nSuppose 3*h - 16221 + 3844 = 5*p, 2*p - 16468 = -4*h. ", "Is h composite?", "\nTrue\nSuppose 5*z = -2*k + 6*k + 15175, 0 = 4*z - 4*k - 12136. ", "Suppose -z = -4*a - 5*m, -3 = m + 2*m. ", "Is a prime?", "\nTrue\nSuppose 3*w + 7 - 16 = 0. ", "Suppose -3*v = -3, -2*v + 449 = w*y + 33. ", "Let j = y + -7. ", "Is j a prime number?", "\nTrue\nLet b = -4322 - -7749. ", "Is b prime?", "\nFalse\nSuppose 3*r - 65887 = 4*w, 3*r + 2*w - 33585 - 32296 = 0. ", "Is r prime?", "\nTrue\nLet r be ((-342)/15)/((-4)/10). ", "Suppose 0 = -5*n + 2*g + r, -n + 39 = 3*n + 5*g. ", "Suppose 4*j + n = h + 73, 54 = 4*j + 3*h. ", "Is j composite?", "\nTrue\nSuppose -23*z + 60 + 32 = 0. ", "Suppose 0 = -3*u - 0*u + 480. ", "Suppose 0 = 5*f - 0*o - 3*o - 160, 4*f + z*o = u. Is f a composite number?", "\nTrue\nSuppose u = 3*j - 11306 - 17090, 0 = -3*j + 5*u + 28376. ", "Is j a prime number?", "\nTrue\nSuppose 0 = 18*d - 56*d + 207898. ", "Is d a composite number?", "\nFalse\nLet h = -71 - -71. ", "Suppose h = 3*l - 2683 - 956. ", "Is l prime?", "\nTrue\nLet c = 968 - 579. ", "Is c a composite number?", "\nFalse\nSuppose -2*l - 5*p = -13, 0 = -5*l - 2*p + 5*p + 79. ", "Suppose -s + 11 = -3*n, 2*s + 4*n + l = 4*s. ", "Is 33 + -6 - s*4 a prime number?", "\nTrue\nSuppose -3*j - 20344 = -11*j. ", "Is j a prime number?", "\nTrue\nLet z = 22 + 354. ", "Suppose l = -2*l + 5*u + z, -4*l + 2*u + 506 = 0. ", "Is l composite?", "\nFalse\nLet n(l) = 6*l + 27. ", "Let u be n(-6). ", "Is (-2975)/(-63) + 2/u a composite number?", "\nFalse\nSuppose 914 - 44 = -3*r. ", "Let z = r + 483. ", "Suppose 41 = s + o - 0*o, -5*s - 2*o + z = 0. ", "Is s prime?", "\nTrue\nLet p be (-29)/(-2) + (-6)/(-12). ", "Suppose 8*g = 3*g + p. Let o(x) = 2*x**3 - 5*x**2 + x + 2. ", "Is o(g) a composite number?", "\nTrue\nLet x(h) = 75*h**2 - 8*h. ", "Let z be x(6). ", "Suppose j - 4*j = -z. ", "Suppose 0*d + 4*d = j. Is d prime?", "\nFalse\nLet a(u) = -u + 7. ", "Let x be a(0). ", "Suppose -4*p = -4*z - 3996, -x*z = 5*p - 4*z - 4979. ", "Is p a composite number?", "\nFalse\nSuppose 35 = 3*g + 26. ", "Suppose -3*y + 1 = 25. ", "Let v = g - y. Is v composite?", "\nFalse\nLet a = -6230 - -10941. ", "Suppose 0 = -6*h - h + a. Is h prime?", "\nTrue\nLet c(o) = -o**2 + 4*o - 4. ", "Let v be c(2). ", "Suppose v*w - 2*w + 4 = 0. ", "Suppose 0*b + 5*f - 232 = -w*b, -b + 4*f = -90. ", "Is b prime?", "\nFalse\nLet w = 32 - 27. ", "Suppose 0 = q + h - 689, w*q - 3475 = 2*h - h. Is q a composite number?", "\nTrue\nIs 1771011/36 - -1*1/4 composite?", "\nTrue\nLet y(m) = -m. ", "Let u(h) = 20*h**2 + 12*h + 18. ", "Let p(d) = u(d) - 12*y(d). ", "Is p(10) prime?", "\nFalse\nLet v be (-199)/(3 + (-95)/30). ", "Let h be ((-210)/(-9))/((-4)/(-294)). ", "Let c = h - v. Is c composite?", "\nFalse\nSuppose -5*s - 4*z + 14 = 0, 4*z + 0 = s + 2. ", "Suppose 5*b - s*a + a = 428, 0 = -3*b - 4*a + 243. ", "Is b a composite number?", "\nTrue\nSuppose -5*b - 13428 = -3*l, 3*b = 6 + 3. ", "Is l a prime number?", "\nTrue\nLet v be (3794/(-8))/7*(-13 - -1). ", "Is v - (-1 + 1*(2 + -3)) composite?", "\nTrue\nSuppose 3*u = 4*f + 20, 4*f - 8 - 20 = -3*u. ", "Let l be (-2)/u + 26/8. ", "Suppose 390 = 3*r - 0*j - l*j, j = 4*r - 529. ", "Is r a composite number?", "\nTrue\nLet u(j) = -238*j**3 + 20*j**2 - 3*j + 2. ", "Is u(-3) prime?", "\nFalse\nSuppose 7154 = 2*g - 3*f + 6*f, 3*f = 5*g - 17843. ", "Is g prime?", "\nTrue\nLet b be (1 - -2) + (-2 - 0). ", "Let m = b + 130. ", "Is m prime?", "\nTrue\nLet c = 102814 - 60191. ", "Is c a composite number?", "\nTrue\nSuppose -10*u + 78436 = -49024. ", "Is u composite?", "\nTrue\nSuppose 2*p = -5*j + 5062 - 144, -p + 3*j + 2481 = 0. ", "Is p prime?", "\nFalse\nLet a(w) = -207*w - 27. ", "Let h be a(10). ", "Let o = 2960 + h. Is o composite?", "\nFalse\nSuppose 5 + 7 = 4*v. ", "Suppose -847 = -v*s - 4*m + 186, 3*s - 1013 = m. Suppose 2*r - 1081 = -s. ", "Is r composite?", "\nTrue\nLet j(q) = -28*q - 35. ", "Is j(-22) prime?", "\nFalse\nLet u be 54/4*((-20)/15 + 2). ", "Is 1 + u/(-5) + 244302/190 a prime number?", "\nFalse\nLet w(l) = 3161*l - 353. ", "Is w(8) a composite number?", "\nTrue\nLet z = -4601 + 9256. ", "Suppose 5*g + 6*i - 4*i = z, 0 = -g + i + 938. ", "Is g composite?", "\nTrue\nLet y = -9 - -8. ", "Let m be -364 + (4/(-1) - y). ", "Let p = m - -746. ", "Is p a composite number?", "\nFalse\nLet i = 4103 - -14976. ", "Is i prime?", "\nTrue\nLet s be (-6)/((-12)/(-5))*-2. ", "Suppose -4*t = -16, 2*u = s*t - 69 + 163. ", "Is u composite?", "\nTrue\nLet l(u) = 3841*u**2 - u. Let b be l(1). ", "Suppose -2*v + 3*c = -7705, 2*v = v - c + b. Is v a composite number?", "\nTrue\nSuppose -3*y - 9235 = 3*n - 8*n, -3*n - 5*y + 5541 = 0. ", "Is n composite?", "\nFalse\nSuppose 3*k - 6*k = -5046. ", "Let t(v) = 4*v - 84. ", "Let s be t(21). ", "Suppose s = -b - b - 6, b = -5*c + k. Is c a prime number?", "\nTrue\nIs (15037165/75)/11 - 2/(-15) a prime number?", "\nFalse\nLet f = -48988 + 81857. ", "Is f a composite number?", "\nFalse\nLet x(b) = 81*b**2 - b - 803. ", "Is x(24) a composite number?", "\nTrue\nLet m(s) = 10 - 4*s + 5*s + s. Suppose d - 6 = -9. ", "Is m(d) prime?", "\nFalse" ]
{ "pile_set_name": "DM Mathematics" }
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0.002093
5
[ "Belly fat may be worse than obesity for survival\n\nPeople with a \"normal\" weight but extra pounds around the middle may have lower long-term survival odds than individuals who are obese, a U.S. study suggests.", "\n\nWhat's considered a normal weight for adults is often based on a measurement known as body mass index (BMI), which assesses weight relative to height. ", "For the current study, researchers focused on people's waist-to-hip ratio, which measures whether they're storing excess fat around the middle.", "\n\nThe found that men with a normal BMI but central obesity, the clinical term for belly fat, had twice the mortality risk of men who were overweight or obese according to BMI.", "\n\nNormal weight women with belly fat, meanwhile, had a 32 percent higher mortality risk than obese women without excess pounds around the middle.", "\n\n\"Waist size matters, particularly in people who are a normal weight,\" said senior study author Dr. Francisco Lopez-Jimenez of the Mayo Clinic in Rochester, Minnesota.", "\n\n\"The lack of recognition of this leads people with abnormal distribution of fat to have a false sense of safety or reassurance that they don't need to exercise or they can eat whatever they want because they are \"skinny\" when in reality, if a person has a normal BMI and an abnormal waist size the risk is worse than if they have a high BMI.\"", "\n\nTo understand the connection between waist size and mortality, researchers analyzed data on more than 15,000 adults surveyed from 1988 to 1994 and then followed through 2006.", "\n\nBased on BMI, about 40 percent of participants were normal weight, while 35 percent were overweight and 25 percent were obese.", "\n\nAccording to World Health Organization (WHO) criteria, about 70 percent of participants were centrally obese, meaning their waist-to-hip ratio was at least 0.85 (for women) or at least 0.90 (for men).", "\n\nAlong with the waist-to-hip ratio, participants' waist circumference was also more helpful than BMI in predicting risk of mortality, although only about 29 percent of people in the study were centrally obese using the WHO sex-specific criteria for waist circumference - more than 88 cm (34.6 inches) for women and more than 102 cm (40.2 inches) in men.", "\n\nOver an average of about 14 years, there 3,222 deaths, including 1404 due to cardiovascular disease.", "\n\nA man with normal-weight central obesity had a 78 percent higher risk of death from cardiovascular disease than a man with a similar BMI but no fat around the middle, the study found.", "\n\nFor women in this same scenario, normal-weight central obesity more than doubled the risk of death from cardiovascular disease.", "\n\nLimitations of the study include a measurement technique for waist circumference that's different than the method recommended by WHO, the authors acknowledge. ", "Researchers also relied on self-reported data for many health complications such as high blood pressure, elevated cholesterol or diabetes.", "\n\nEven so, the findings provide ample evidence suggesting that doctors should look beyond just BMI to identify people who are at the greatest risk due to excess pounds, Dr. Paul Poirier, of Laval University and the Quebec Heart and Lung Institute, noted in an editorial.", "\n\nMeasuring BMI is a good start for identifying patients at greater cardiovascular risk, but it is not sufficient to identify every person at risk, Poirier wrote.", "\n\n\"We need to talk about waist loss and not weight loss,\" Poirier said by email. \"", "When you lose weight through exercise and proper nutrition then the first fat to go is the fat at the waist line.\"", "\n\nMore on this...\n\nSome preliminary research has previously pointed to the potential for diets low in carbohydrates to help eliminate waist fat, though more research on this is still needed, Lopez-Jimenez noted.", "\n\nBecause people with normal weight and excess pounds around the middle may not have as much muscle mass as people without belly fat, these individuals may benefit from an exercise routine that includes strength and resistance training in addition to aerobic activity, Lopez-Jimenez added." ]
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0.004906
5
[ "Rv Satellite Wiring Diagram\nDownload\n\nCollection of rv satellite wiring diagram. ", "A wiring diagram is a streamlined conventional photographic representation of an electric circuit. ", "It shows the elements of the circuit as simplified forms, as well as the power and also signal connections between the devices.", "\n\nA wiring diagram typically offers information regarding the family member position and also setup of devices and also terminals on the devices, to assist in structure or servicing the gadget. ", "This differs from a schematic diagram, where the plan of the components’ affiliations on the representation usually does not match to the components’ physical areas in the finished tool. ", "A photographic representation would certainly show extra information of the physical appearance, whereas a wiring diagram utilizes a much more symbolic symbols to stress affiliations over physical appearance.", "\n\nA wiring diagram is commonly made use of to repair problems and making sure that the connections have been made which everything is existing.", "\n\nAssortment of rv satellite wiring diagram. ", "Click on the image to enlarge, and then save it to your computer by right clicking on the image.", "\n\nSatellite Dish Wiring Diagram Collection\n\nSatellite Dish Wiring Diagram Collection\n\nCoaxial Cable Wiring Diagram Lovely Elegant Rv Cable and Satellite\n\nHow Long is Directv Contract Luxury Elegant Rv Cable and Satellite\n\nRv Electrical Wiring Diagram Beautiful Elegant Rv Cable and\n\nSatellite Tv Wiring Diagrams\n\nA Novice s Guide to Circuit Diagrams\n\nA very first appearance at a circuit diagram might be complex, however if you can check out a subway map, you could check out schematics. ", "The function is the same: getting from factor A to direct B. Literally, a circuit is the path that permits power to circulation.", "\n\nThe Language of Wiring\n\nAllow s look at some of terms that you will require to recognize:\n\nVoltage: Gauged in volts (V), voltage is the pressure or pressure of electrical energy. ", "This is usually provided by a battery (such as a 9V battery) or mains electricity, the electrical outlets in your house operate at 120V. Outlets in various other countries run at a various voltage, which is why you need a converter when taking a trip.", "\n\nPresent: Current is the circulation of electricity, or more specifically, the circulation of electrons. ", "It is determined in Amperes (Amps), as well as could just flow when a voltage supply is connected.", "\n\nResistance: Gauged in Ohms (R or O), resistance specifies how conveniently electrons can stream through a material. ", "Products such as gold or copper, are called conductors, as they quickly allow flow of movement (reduced resistance). ", "Plastic, wood, and air are examples of insulators, inhibiting the motion of electrons (high resistance).", "\n\nDC (Direct Current). ", "DC is a continuous flow of present in one instructions. ", "DC could move not simply via conductors, yet semi-conductors, insulators, and also even a vacuum.", "\n\nAir Conditioning (Rotating Current). ", "In A/C, the circulation of existing occasionally alternates between two instructions, often forming a sine wave. ", "The frequency of A/C is determined in Hertz (Hz), as well as is normally 60 Hz for electrical energy in domestic and company functions.", "\n\nThe Schematics\n\nFinishing an electrical design level and also after that getting a work in the field means you will certainly see a whole lot a lot a lot of these schematics. ", "It s essential to understand specifically just what is going on with these.", "\n\nBeginning to make sense? ", "These are the essentials and also may also seem noticeable or instinctive to you, such as the wires and if they are connected. ", "Whenever you establish your specific field of electric engineering, you could see much more complex layouts and also icons. ", "You ll learn likewise that different nations use different icons. ", "For instance, of both signs for resistors above, the very first one is made use of in the United States, while the second is used in Europe. ", "You will certainly also learn about the various icons used for switches, various other power products, inductors, meters, lamps, LEDs, transistors, antennas, and far more." ]
{ "pile_set_name": "Pile-CC" }
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0.001178
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[ "//\n// ********************************************************************\n// * License and Disclaimer *\n// * *\n// * The Geant4 software is copyright of the Copyright Holders of *\n// * the Geant4 Collaboration. ", " It is provided under the terms and *\n// * conditions of the Geant4 Software License, included in the file *\n// * LICENSE and available at http://cern.ch/geant4/license . ", " These *\n// * include a list of copyright holders. ", " *\n// * *\n// * Neither the authors of this software system, nor their employing *\n// * institutes,nor the agencies providing financial support for this *\n// * work make any representation or warranty, express or implied, *\n// * regarding this software system or assume any liability for its *\n// * use. ", " Please see the license in the file LICENSE and URL above *\n// * for the full disclaimer and the limitation of liability. ", " *\n// * *\n// * This code implementation is the result of the scientific and *\n// * technical work of the GEANT4 collaboration. ", " *\n// * By using, copying, modifying or distributing the software (or *\n// * any work based on the software) you agree to acknowledge its *\n// * use in resulting scientific publications, and indicate your *\n// * acceptance of all terms of the Geant4 Software license. ", " *\n// ********************************************************************\n//\n//\n//\n//\n// G4 Physics class: G4ChipsKaonPlusElasticXS for pA elastic cross sections\n// Created: M.V. Kossov, CERN/ITEP(Moscow), 5-Feb-2010\n// The last update: M.V. Kossov, CERN/ITEP (Moscow) 5-Feb-2010\n// \n// -------------------------------------------------------------------------------\n// Short description: Interaction cross-sections for the elastic process. ", "\n// Class extracted from CHIPS and integrated in Geant4 by W.Pokorski\n// -------------------------------------------------------------------------------\n//\n\n#include \"G4ChipsKaonPlusElasticXS.hh\"\n#include \"G4SystemOfUnits.hh\"\n#include \"G4DynamicParticle.hh\"\n#include \"G4ParticleDefinition.hh\"\n#include \"G4KaonPlus.hh\"\n#include \"G4Nucleus.hh\"\n#include \"G4ParticleTable.hh\"\n#include \"G4NucleiProperties.hh\"\n#include \"G4IonTable.hh\"\n#include \"G4AutoLock.hh\"\n// factory\n#include \"G4CrossSectionFactory.hh\"\n//\nG4_DECLARE_XS_FACTORY(G4ChipsKaonPlusElasticXS);\n\nnamespace {\n G4double mK;//= G4KaonPlus::KaonPlus()->GetPDGMass()*.001; // MeV to GeV //Cannot initialize here, needs particles\n G4double mK2;//= mK*mK;\n G4Mutex initM = G4MUTEX_INITIALIZER;\n const G4double pwd=2727;\n const G4double GeVSQ=gigaelectronvolt*gigaelectronvolt;\n const G4double third=1./3.;", "\n const G4double fifth=1./5.;", "\n const G4double sevth=1./7.;", "\n const G4double HGeVSQ=gigaelectronvolt*gigaelectronvolt/2.;", "\n // @@ At present all nA==pA ---------> Each neucleus can have not more than 51 parameters\n const G4int n_kppel=35; // #of parameters for pp-elastic (<nPoints=128)\n // -0--1- -2- -3- -4- -5- -6--7--8--9- -10--11-12--13--14-\n G4double kpp_el[n_kppel]={.7,.38,.0676,.0557,3.5,2.23,.7,.1,2.,1.,.372,5.,74.,3.,3.4,\n .2,.17,.001,8.,.055,3.64,5.e-5,4000.,1500.,.46,1.2e6,3.5e6,\n 5.e-5,1.e10,8.5e8,1.e10,1.1,3.4e6,6.8e6,0.};", "\n // -15--16--17--18--19- -20- -21- -22- -23- -24- -25- -26-\n // -27- -28- -29- -30- -31- -32- -33--34-\n \n\n}\n\nG4ChipsKaonPlusElasticXS::G4ChipsKaonPlusElasticXS():G4VCrossSectionDataSet(Default_Name()), nPoints(128), nLast(nPoints-1)\n{\n G4AutoLock l(&initM);\n mK = G4KaonPlus::KaonPlus()->GetPDGMass()*.001;// MeV to GeV\n mK2 = mK*mK;\n l.unlock();\n lPMin=-8.; ", " //Min tabulatedLogarithmMomentum/D\n lPMax= 8.; ", " //Max tabulatedLogarithmMomentum/D\n dlnP=(lPMax-lPMin)/nLast;// LogStep inTable /D\n onlyCS=true;//Flag toCalculOnlyCS(not Si/Bi)/L\n lastSIG=0.; ", "//Last calculated cross section /L\n lastLP=-10.;//LastLog(mom_of IncidentHadron)/L\n lastTM=0.; ", "//Last t_maximum /L\n theSS=0.; ", " //TheLastSqSlope of 1st difr.", "Max/L\n theS1=0.; ", " //TheLastMantissa of 1st difrMax/L\n theB1=0.; ", " //TheLastSlope of 1st difructMax/L\n theS2=0.; ", " //TheLastMantissa of 2nd difrMax/L\n theB2=0.; ", " //TheLastSlope of 2nd difructMax/L\n theS3=0.; ", " //TheLastMantissa of 3d difr.", "Max/L\n theB3=0.; ", " //TheLastSlope of 3d difruct.", "Max/L\n theS4=0.; ", " //TheLastMantissa of 4th difrMax/L\n theB4=0.; ", " //TheLastSlope of 4th difructMax/L\n lastTZ=0; // Last atomic number of theTarget\n lastTN=0; // Last # of neutrons in theTarget\n lastPIN=0.;// Last initialized max momentum\n lastCST=0; // Elastic cross-section table\n lastPAR=0; // ParametersForFunctionCalculation\n lastSST=0; // E-dep ofSqardSlope of 1st difMax\n lastS1T=0; // E-dep of mantissa of 1st dif.", "Max\n lastB1T=0; // E-dep of the slope of 1st difMax\n lastS2T=0; // E-dep of mantissa of 2nd difrMax\n lastB2T=0; // E-dep of the slope of 2nd difMax\n lastS3T=0; // E-dep of mantissa of 3d difr.", "Max\n lastB3T=0; // E-dep of the slope of 3d difrMax\n lastS4T=0; // E-dep of mantissa of 4th difrMax\n lastB4T=0; // E-dep of the slope of 4th difMax\n lastN=0; // The last N of calculated nucleus\n lastZ=0; // The last Z of calculated nucleus\n lastP=0.; ", " // LastUsed inCrossSection Momentum\n lastTH=0.; // ", "Last threshold momentum\n lastCS=0.; // ", "Last value of the Cross Section\n lastI=0; // The last position in the DAMDB\n}\n\nG4ChipsKaonPlusElasticXS::~G4ChipsKaonPlusElasticXS()\n{\n std::vector<G4double*>::iterator pos;\n for (pos=CST.begin(); pos<CST.end(); pos++)\n { delete [] *pos; }\n CST.clear();\n for (pos=PAR.begin(); pos<PAR.end(); pos++)\n { delete [] *pos; }\n PAR.clear();\n for (pos=SST.begin(); pos<SST.end(); pos++)\n { delete [] *pos; }\n SST.clear();\n for (pos=S1T.begin(); pos<S1T.end(); pos++)\n { delete [] *pos; }\n S1T.clear();\n for (pos=B1T.begin(); pos<B1T.end(); pos++)\n { delete [] *pos; }\n B1T.clear();\n for (pos=S2T.begin(); pos<S2T.end(); pos++)\n { delete [] *pos; }\n S2T.clear();\n for (pos=B2T.begin(); pos<B2T.end(); pos++)\n { delete [] *pos; }\n B2T.clear();\n for (pos=S3T.begin(); pos<S3T.end(); pos++)\n { delete [] *pos; }\n S3T.clear();\n for (pos=B3T.begin(); pos<B3T.end(); pos++)\n { delete [] *pos; }\n B3T.clear();\n for (pos=S4T.begin(); pos<S4T.end(); pos++)\n { delete [] *pos; }\n S4T.clear();\n for (pos=B4T.begin(); pos<B4T.end(); pos++)\n { delete [] *pos; }\n B4T.clear();\n}\n\nvoid\nG4ChipsKaonPlusElasticXS::CrossSectionDescription(std::ostream& outFile) const\n{\n outFile << \"G4ChipsKaonPlusElasticXS provides the elastic cross\\n\"\n << \"section for K+ nucleus scattering as a function of incident\\n\"\n << \"momentum. ", "The cross section is calculated using M. Kossov's\\n\"\n << \"CHIPS parameterization of cross section data.\\n\";\n}\n\n\nG4bool G4ChipsKaonPlusElasticXS::IsIsoApplicable(const G4DynamicParticle*, G4int, G4int, \n\t\t\t\t\t\t const G4Element*,\n\t\t\t\t\t\t const G4Material*)\n{\n return true;\n}\n\n// The main member function giving the collision cross section (P is in IU, CS is in mb)\n// Make pMom in independent units ! (", "Now it is MeV)\nG4double G4ChipsKaonPlusElasticXS::GetIsoCrossSection(const G4DynamicParticle* Pt, G4int tgZ, G4int A, \n\t\t\t\t\t\t\tconst G4Isotope*,\n\t\t\t\t\t\t\tconst G4Element*,\n\t\t\t\t\t\t\tconst G4Material*)\n{\n G4double pMom=Pt->GetTotalMomentum();\n G4int tgN = A - tgZ;\n \n return GetChipsCrossSection(pMom, tgZ, tgN, 321);\n}\n\nG4double G4ChipsKaonPlusElasticXS::GetChipsCrossSection(G4double pMom, G4int tgZ, G4int tgN, G4int)\n{\n\n G4bool fCS = false;\n G4double pEn=pMom;\n onlyCS=fCS;\n\n G4bool in=false; // By default the isotope must be found in the AMDB\n lastP = 0.; ", " // New momentum history (nothing to compare with)\n lastN = tgN; // The last N of the calculated nucleus\n lastZ = tgZ; // The last Z of the calculated nucleus\n lastI = colN.size(); // Size of the Associative Memory DB in the heap\n if(lastI) for(G4int i=0; i<lastI; i++) // Loop over proj/tgZ/tgN lines of DB\n { // The nucleus with projPDG is found in AMDB\n if(colN[i]==tgN && colZ[i]==tgZ) // Isotope is foind in AMDB\n {\n lastI=i;\n lastTH =colTH[i]; // Last THreshold (A-dependent)\n if(pEn<=lastTH)\n {\n return 0.; ", " // Energy is below the Threshold value\n }\n lastP =colP [i]; // Last Momentum (A-dependent)\n lastCS =colCS[i]; // Last CrossSect (A-dependent)\n // if(std::fabs(lastP/pMom-1.)<tolerance) //VI (do not use tolerance)\n if(lastP == pMom) // Do not recalculate\n {\n CalculateCrossSection(fCS,-1,i,321,lastZ,lastN,pMom); // Update param's only\n return lastCS*millibarn; // Use theLastCS\n }\n in = true; // This is the case when the isotop is found in DB\n // Momentum pMom is in IU ! @@ ", "Units\n lastCS=CalculateCrossSection(fCS,-1,i,321,lastZ,lastN,pMom); // read & update\n if(lastCS<=0. && ", "pEn>lastTH) // Correct the threshold\n {\n lastTH=pEn;\n }\n break; // Go out of the LOOP with found lastI\n }\n } // End of attampt to find the nucleus in DB\n if(!in) // This nucleus has not been calculated previously\n {\n //!!The slave functions must provide cross-sections in millibarns (mb) !! (", "not in IU)\n lastCS=CalculateCrossSection(fCS,0,lastI,321,lastZ,lastN,pMom);//calculate&create\n if(lastCS<=0.)", "\n {\n lastTH = 0; //ThresholdEnergy(tgZ, tgN); // The Threshold Energy which is now the last\n if(pEn>lastTH)\n {\n lastTH=pEn;\n }\n }\n colN.push_back(tgN);\n colZ.push_back(tgZ);\n colP.push_back(pMom);\n colTH.push_back(lastTH);\n colCS.push_back(lastCS);\n return lastCS*millibarn;\n } // End of creation of the new set of parameters\n else\n {\n colP[lastI]=pMom;\n colCS[lastI]=lastCS;\n }\n return lastCS*millibarn;\n}\n\n// Calculation of total elastic cross section (p in IU, CS in mb) @@ Units (?)", "\n// F=0 - create AMDB, F=-1 - read&update AMDB, F=1 - update AMDB (sinchro with higher AMDB)\nG4double G4ChipsKaonPlusElasticXS::CalculateCrossSection(G4bool CS, G4int F,\n G4int I, G4int PDG, G4int tgZ, G4int tgN, G4double pIU)\n{\n G4double pMom=pIU/GeV; // All calculations are in GeV\n onlyCS=CS; // Flag to calculate only CS (not Si/Bi)\n lastLP=std::log(pMom); // Make a logarithm of the momentum for calculation\n if(F) // This isotope was found in AMDB =>RETRIEVE/UPDATE\n {\n if(F<0) // the AMDB must be loded\n {\n lastPIN = PIN[I]; // Max log(P) initialised for this table set\n lastPAR = PAR[I]; // Pointer to the parameter set\n lastCST = CST[I]; // Pointer to the total sross-section table\n lastSST = SST[I]; // Pointer to the first squared slope\n lastS1T = S1T[I]; // Pointer to the first mantissa\n lastB1T = B1T[I]; // Pointer to the first slope\n lastS2T = S2T[I]; // Pointer to the second mantissa\n lastB2T = B2T[I]; // Pointer to the second slope\n lastS3T = S3T[I]; // Pointer to the third mantissa\n lastB3T = B3T[I]; // Pointer to the rhird slope\n lastS4T = S4T[I]; // Pointer to the 4-th mantissa\n lastB4T = B4T[I]; // Pointer to the 4-th slope\n }\n if(lastLP>lastPIN && lastLP<lPMax)\n {\n lastPIN=GetPTables(lastLP,lastPIN,PDG,tgZ,tgN);// Can update upper logP-Limit in tabs\n PIN[I]=lastPIN; // Remember the new P-Limit of the tables\n }\n }\n else // This isotope wasn't initialized => CREATE\n {\n lastPAR = new G4double[nPoints]; // Allocate memory for parameters of CS function\n lastPAR[nLast]=0; // Initialization for VALGRIND\n lastCST = new G4double[nPoints]; // Allocate memory for Tabulated CS function \n lastSST = new G4double[nPoints]; // Allocate memory for Tabulated first sqaredSlope \n lastS1T = new G4double[nPoints]; // Allocate memory for Tabulated first mantissa \n lastB1T = new G4double[nPoints]; // Allocate memory for Tabulated first slope \n lastS2T = new G4double[nPoints]; // Allocate memory for Tabulated second mantissa\n lastB2T = new G4double[nPoints]; // Allocate memory for Tabulated second slope \n lastS3T = new G4double[nPoints]; // Allocate memory for Tabulated third mantissa \n lastB3T = new G4double[nPoints]; // Allocate memory for Tabulated third slope \n lastS4T = new G4double[nPoints]; // Allocate memory for Tabulated 4-th mantissa \n lastB4T = new G4double[nPoints]; // Allocate memory for Tabulated 4-th slope \n lastPIN = GetPTables(lastLP,lPMin,PDG,tgZ,tgN); // Returns the new P-limit for tables\n PIN.push_back(lastPIN); // Fill parameters of CS function to AMDB\n PAR.push_back(lastPAR); // Fill parameters of CS function to AMDB\n CST.push_back(lastCST); // Fill Tabulated CS function to AMDB \n SST.push_back(lastSST); // Fill Tabulated first sq.slope to AMDB \n S1T.push_back(lastS1T); // Fill Tabulated first mantissa to AMDB \n B1T.push_back(lastB1T); // Fill Tabulated first slope to AMDB \n S2T.push_back(lastS2T); // Fill Tabulated second mantissa to AMDB \n B2T.push_back(lastB2T); // Fill Tabulated second slope to AMDB \n S3T.push_back(lastS3T); // Fill Tabulated third mantissa to AMDB \n B3T.push_back(lastB3T); // Fill Tabulated third slope to AMDB \n S4T.push_back(lastS4T); // Fill Tabulated 4-th mantissa to AMDB \n B4T.push_back(lastB4T); // Fill Tabulated 4-th slope to AMDB \n } // End of creation/update of the new set of parameters and tables\n // =----------= NOW Update (if necessary) and Calculate the Cross Section =----------=\n if(lastLP>lastPIN && lastLP<lPMax)\n {\n lastPIN = GetPTables(lastLP,lastPIN,PDG,tgZ,tgN);\n }\n if(!onlyCS) lastTM=GetQ2max(PDG, tgZ, tgN, pMom); // Calculate (-t)_max=Q2_max (GeV2)\n if(lastLP>lPMin && lastLP<=lastPIN) // Linear fit is made using precalculated tables\n {\n if(lastLP==lastPIN)\n {\n G4double shift=(lastLP-lPMin)/dlnP+.000001; // Log distance from lPMin\n G4int blast=static_cast<int>(shift); // this is a bin number of the lower edge (0)\n if(blast<0 || blast>=nLast) G4cout<<\"G4QKPElCS::CCS:b=\"<<blast<<\",n=\"<<nLast<<G4endl;\n lastSIG = lastCST[blast];\n if(!onlyCS) // Skip the differential cross-section parameters\n {\n theSS = lastSST[blast];\n theS1 = lastS1T[blast];\n theB1 = lastB1T[blast];\n theS2 = lastS2T[blast];\n theB2 = lastB2T[blast];\n theS3 = lastS3T[blast];\n theB3 = lastB3T[blast];\n theS4 = lastS4T[blast];\n theB4 = lastB4T[blast];\n }\n }\n else\n {\n G4double shift=(lastLP-lPMin)/dlnP; // a shift from the beginning of the table\n G4int blast=static_cast<int>(shift); // the lower bin number\n if(blast<0) blast=0;\n if(blast>=nLast) blast=nLast-1; // low edge of the last bin\n shift-=blast; // step inside the unit bin\n G4int lastL=blast+1; // the upper bin number\n G4double SIGL=lastCST[blast]; // the basic value of the cross-section\n lastSIG= SIGL+shift*(lastCST[lastL]-SIGL); // calculated total elastic cross-section\n if(!onlyCS) // Skip the differential cross-section parameters\n {\n G4double SSTL=lastSST[blast]; // the low bin of the first squared slope\n theSS=SSTL+shift*(lastSST[lastL]-SSTL); // the basic value of the first sq.slope\n G4double S1TL=lastS1T[blast]; // the low bin of the first mantissa\n theS1=S1TL+shift*(lastS1T[lastL]-S1TL); // the basic value of the first mantissa\n G4double B1TL=lastB1T[blast]; // the low bin of the first slope\n theB1=B1TL+shift*(lastB1T[lastL]-B1TL); // the basic value of the first slope\n G4double S2TL=lastS2T[blast]; // the low bin of the second mantissa\n theS2=S2TL+shift*(lastS2T[lastL]-S2TL); // the basic value of the second mantissa\n G4double B2TL=lastB2T[blast]; // the low bin of the second slope\n theB2=B2TL+shift*(lastB2T[lastL]-B2TL); // the basic value of the second slope\n G4double S3TL=lastS3T[blast]; // the low bin of the third mantissa\n theS3=S3TL+shift*(lastS3T[lastL]-S3TL); // the basic value of the third mantissa\n G4double B3TL=lastB3T[blast]; // the low bin of the third slope\n theB3=B3TL+shift*(lastB3T[lastL]-B3TL); // the basic value of the third slope\n G4double S4TL=lastS4T[blast]; // the low bin of the 4-th mantissa\n theS4=S4TL+shift*(lastS4T[lastL]-S4TL); // the basic value of the 4-th mantissa\n G4double B4TL=lastB4T[blast]; // the low bin of the 4-th slope\n theB4=B4TL+shift*(lastB4T[lastL]-B4TL); // the basic value of the 4-th slope\n }\n }\n }\n else lastSIG=GetTabValues(lastLP, PDG, tgZ, tgN); // Direct calculation beyond the table\n if(lastSIG<0.) ", "lastSIG = 0.; ", " // @@ a Warning print can be added\n return lastSIG;\n}\n\n// It has parameter sets for all tZ/tN/PDG, using them the tables can be created/updated\nG4double G4ChipsKaonPlusElasticXS::GetPTables(G4double LP,G4double ILP, G4int PDG,\n G4int tgZ, G4int tgN)\n{\n if(PDG == 321)\n {\n // -- Total pp elastic cross section cs & s1/b1 (main), s2/b2 (tail1), s3/b3 (tail2) --\n //p2=p*p;p3=p2*p;sp=sqrt(p);p2s=p2*sp;lp=log(p);dl1=lp-(3.=par(3));p4=p2*p2; p=|3-mom|\n //CS=2.865/p2s/(1+.0022/p2s)+(18.9+.6461*dl1*dl1+9./p)/(1.+.425*lp)/(1.+.4276/p4);\n // par(0) par(7) par(1) par(2) par(4) par(5) par(6)\n //dl2=lp-5., ", "s1=(74.+3.*dl2*dl2)/(1+3.4/p4/p)+(.2/p2+17.*p)/(p4+.001*sp),\n // par(8) par(9) par(10) par(11) par(12)par(13) par(14)\n // b1=8.*p**.055/(1.+3.64/p3); s2=5.e-5+4000./(p4+1500.*p); b2=.46+1.2e6/(p4+3.5e6/sp);\n // par(15) par(16) par(17) par(18) par(19) par(20) par(21) par(22) par(23)\n // s3=5.e-5+1.e10/(p4*p4+8.5e8*p2+1.e10); b3=1.1+3.4e6/(p4+6.8e6); ss=0.", "\n // par(24) par(25) par(26) par(27) par(28) par(29) par(30) par(31)\n //\n if(lastPAR[nLast]!=pwd) // A unique flag to avoid the repeatable definition\n {\n if ( tgZ == 1 && tgN == 0 )\n {\n for (G4int ip=0; ip<n_kppel; ip++) lastPAR[ip]=kpp_el[ip]; // KPlus+P\n }\n else\n {\n G4double a=tgZ+tgN;\n G4double sa=std::sqrt(a);\n G4double ssa=std::sqrt(sa);\n G4double asa=a*sa;\n G4double a2=a*a;\n G4double a3=a2*a;\n G4double a4=a3*a;\n G4double a5=a4*a;\n G4double a6=a4*a2;\n G4double a7=a6*a;\n G4double a8=a7*a;\n G4double a9=a8*a;\n G4double a10=a5*a5;\n G4double a12=a6*a6;\n G4double a14=a7*a7;\n G4double a16=a8*a8;\n G4double a17=a16*a;\n //G4double a20=a16*a4;\n G4double a32=a16*a16;\n // Reaction cross-section parameters (kpael_fit.f)\n lastPAR[0]=.06*asa/(1.+a*(.01+.1/ssa)); // p1\n lastPAR[1]=.75*asa/(1.+.009*a); // p2\n lastPAR[2]=.9*asa*ssa/(1.+.03*a); // p3\n lastPAR[3]=3.; ", " // p4\n lastPAR[4]=4.2; // p5\n lastPAR[5]=0.; ", " // p6 not used\n lastPAR[6]=0.; ", " // p7 not used\n lastPAR[7]=0.; ", " // p8 not used\n lastPAR[8]=0.; ", " // p9 not used\n // @@ the differential cross-section is parameterized separately for A>6 & A<7\n if(a<6.5)\n {\n G4double a28=a16*a12;\n // The main pre-exponent (pel_sg)\n lastPAR[ 9]=4000*a; // p1\n lastPAR[10]=1.2e7*a8+380*a17; // p2\n lastPAR[11]=.7/(1.+4.e-12*a16); // p3\n lastPAR[12]=2.5/a8/(a4+1.e-16*a32); // p4\n lastPAR[13]=.28*a; // p5\n lastPAR[14]=1.2*a2+2.3; // p6\n lastPAR[15]=3.8/a; // p7\n // The main slope (pel_sl)\n lastPAR[16]=.01/(1.+.0024*a5); // p1\n lastPAR[17]=.2*a; // p2\n lastPAR[18]=9.e-7/(1.+.035*a5); // p3\n lastPAR[19]=(42.+2.7e-11*a16)/(1.+.14*a); // p4\n // The main quadratic (pel_sh)\n lastPAR[20]=2.25*a3; // p1\n lastPAR[21]=18.; ", " // p2\n lastPAR[22]=2.4e-3*a8/(1.+2.6e-4*a7); // p3\n lastPAR[23]=3.5e-36*a32*a8/(1.+5.e-15*a32/a); // p4\n // The 1st max pre-exponent (pel_qq)\n lastPAR[24]=1.e5/(a8+2.5e12/a16); // p1\n lastPAR[25]=8.e7/(a12+1.e-27*a28*a28); // p2 \n lastPAR[26]=.0006*a3; // p3\n // The 1st max slope (pel_qs)\n lastPAR[27]=10.+4.e-8*a12*a; // p1\n lastPAR[28]=.114; // p2\n lastPAR[29]=.003; // p3\n lastPAR[30]=2.e-23; // p4\n // The effective pre-exponent (pel_ss)\n lastPAR[31]=1./(1.+.0001*a8); // p1\n lastPAR[32]=1.5e-4/(1.+5.e-6*a12); // p2\n lastPAR[33]=.03; // p3\n // The effective slope (pel_sb)\n lastPAR[34]=a/2; // p1\n lastPAR[35]=2.e-7*a4; // p2\n lastPAR[36]=4.; ", " // p3\n lastPAR[37]=64./a3; // p4\n // The gloria pre-exponent (pel_us)\n lastPAR[38]=1.e8*std::exp(.32*asa); // p1\n lastPAR[39]=20.*std::exp(.45*asa); // p2\n lastPAR[40]=7.e3+2.4e6/a5; // p3\n lastPAR[41]=2.5e5*std::exp(.085*a3); // p4\n lastPAR[42]=2.5*a; // p5\n // The gloria slope (pel_ub)\n lastPAR[43]=920.+.03*a8*a3; // p1\n lastPAR[44]=93.+.0023*a12; // p2\n }\n else\n {\n G4double p1a10=2.2e-28*a10;\n G4double r4a16=6.e14/a16;\n G4double s4a16=r4a16*r4a16;\n // a24\n // a36\n // The main pre-exponent (peh_sg)\n lastPAR[ 9]=4.5*std::pow(a,1.15); // p1\n lastPAR[10]=.06*std::pow(a,.6); // p2\n lastPAR[11]=.6*a/(1.+2.e15/a16); // p3\n lastPAR[12]=.17/(a+9.e5/a3+1.5e33/a32); // p4\n lastPAR[13]=(.001+7.e-11*a5)/(1.+4.4e-11*a5); // p5\n lastPAR[14]=(p1a10*p1a10+2.e-29)/(1.+2.e-22*a12); // p6\n // The main slope (peh_sl)\n lastPAR[15]=400./a12+2.e-22*a9; // p1\n lastPAR[16]=1.e-32*a12/(1.+5.e22/a14); // p2\n lastPAR[17]=1000./a2+9.5*sa*ssa; // p3\n lastPAR[18]=4.e-6*a*asa+1.e11/a16; // p4\n lastPAR[19]=(120./a+.002*a2)/(1.+2.e14/a16); // p5\n lastPAR[20]=9.+100./a; // p6\n // The main quadratic (peh_sh)\n lastPAR[21]=.002*a3+3.e7/a6; // p1\n lastPAR[22]=7.e-15*a4*asa; // p2\n lastPAR[23]=9000./a4; // p3\n // The 1st max pre-exponent (peh_qq)\n lastPAR[24]=.0011*asa/(1.+3.e34/a32/a4); // p1\n lastPAR[25]=1.e-5*a2+2.e14/a16; // p2\n lastPAR[26]=1.2e-11*a2/(1.+1.5e19/a12); // p3\n lastPAR[27]=.016*asa/(1.+5.e16/a16); // p4\n // The 1st max slope (peh_qs)\n lastPAR[28]=.002*a4/(1.+7.e7/std::pow(a-6.83,14)); // p1\n lastPAR[29]=2.e6/a6+7.2/std::pow(a,.11); // p2\n lastPAR[30]=11.*a3/(1.+7.e23/a16/a8); // p3\n lastPAR[31]=100./asa; // p4\n // The 2nd max pre-exponent (peh_ss)\n lastPAR[32]=(.1+4.4e-5*a2)/(1.+5.e5/a4); // p1\n lastPAR[33]=3.5e-4*a2/(1.+1.e8/a8); // p2\n lastPAR[34]=1.3+3.e5/a4; // p3\n lastPAR[35]=500./(a2+50.)+3; // p4\n lastPAR[36]=1.e-9/a+s4a16*s4a16; // p5\n // The 2nd max slope (peh_sb)\n lastPAR[37]=.4*asa+3.e-9*a6; // p1\n lastPAR[38]=.0005*a5; // p2\n lastPAR[39]=.002*a5; // p3\n lastPAR[40]=10.; ", " // p4\n // The effective pre-exponent (peh_us)\n lastPAR[41]=.05+.005*a; // p1\n lastPAR[42]=7.e-8/sa; // p2\n lastPAR[43]=.8*sa; // p3\n lastPAR[44]=.02*sa; // p4\n lastPAR[45]=1.e8/a3; // p5\n lastPAR[46]=3.e32/(a32+1.e32); // p6\n // The effective slope (peh_ub)\n lastPAR[47]=24.; ", " // p1\n lastPAR[48]=20./sa; // p2\n lastPAR[49]=7.e3*a/(sa+1.); ", " // p3\n lastPAR[50]=900.*sa/(1.+500./a3); // p4\n }\n // Parameter for lowEnergyNeutrons\n lastPAR[51]=1.e15+2.e27/a4/(1.+2.e-18*a16);\n }\n lastPAR[nLast]=pwd;\n // and initialize the zero element of the table\n G4double lp=lPMin; // ln(momentum)\n G4bool memCS=onlyCS; // ??", "\n onlyCS=false;\n lastCST[0]=GetTabValues(lp, PDG, tgZ, tgN); // Calculate AMDB tables\n onlyCS=memCS;\n lastSST[0]=theSS;\n lastS1T[0]=theS1;\n lastB1T[0]=theB1;\n lastS2T[0]=theS2;\n lastB2T[0]=theB2;\n lastS3T[0]=theS3;\n lastB3T[0]=theB3;\n lastS4T[0]=theS4;\n lastB4T[0]=theB4;\n }\n if(LP>ILP)\n {\n G4int ini = static_cast<int>((ILP-lPMin+.000001)/dlnP)+1; // already inited till this\n if(ini<0) ini=0;\n if(ini<nPoints)\n {\n G4int fin = static_cast<int>((LP-lPMin)/dlnP)+1; // final bin of initialization\n if(fin>=nPoints) fin=nLast; // Limit of the tabular initialization\n if(fin>=ini)\n {\n G4double lp=0.;", "\n for(G4int ip=ini; ip<=fin; ip++) // Calculate tabular CS,S1,B1,S2,B2,S3,B3\n {\n lp=lPMin+ip*dlnP; // ln(momentum)\n G4bool memCS=onlyCS;\n onlyCS=false;\n lastCST[ip]=GetTabValues(lp, PDG, tgZ, tgN); // Calculate AMDB tables (ret CS)\n onlyCS=memCS;\n lastSST[ip]=theSS;\n lastS1T[ip]=theS1;\n lastB1T[ip]=theB1;\n lastS2T[ip]=theS2;\n lastB2T[ip]=theB2;\n lastS3T[ip]=theS3;\n lastB3T[ip]=theB3;\n lastS4T[ip]=theS4;\n lastB4T[ip]=theB4;\n }\n return lp;\n }\n else G4cout<<\"*Warning*G4ChipsKaonPlusElasticXS::GetPTables: PDG=\"<<PDG\n <<\", Z=\"<<tgZ<<\", N=\"<<tgN<<\", i=\"<<ini<<\" > fin=\"<<fin<<\", LP=\"<<LP\n <<\" > ILP=\"<<ILP<<\" nothing is done!\"<<G4endl;\n }\n else G4cout<<\"*Warning*G4ChipsKaonPlusElasticXS::GetPTables: PDG=\"<<PDG\n <<\", Z=\"<<tgZ<<\", N=\"<<tgN<<\", i=\"<<ini<<\">= max=\"<<nPoints<<\", LP=\"<<LP\n <<\" > ILP=\"<<ILP<<\", lPMax=\"<<lPMax<<\" nothing is done!\"<<G4endl;\n }\n }\n else\n {\n // G4cout<<\"*Error*G4ChipsKaonPlusElasticXS::GetPTables: PDG=\"<<PDG<<\", Z=\"<<tgZ\n // <<\", N=\"<<tgN<<\", while it is defined only for PDG=321\"<<G4endl;\n // throw G4QException(\"G4ChipsKaonPlusElasticXS::GetPTables:onlyK+ is implemented\");\n G4ExceptionDescription ed;\n ed << \"PDG = \" << PDG << \", Z = \" << tgZ << \", N = \" << tgN\n << \", while it is defined only for PDG=321 (K+) \" << G4endl;\n G4Exception(\"G4ChipsKaonPlusElasticXS::GetPTables()\", \"HAD_CHPS_0000\",\n FatalException, ed);\n }\n return ILP;\n}\n\n// Returns Q2=-t in independent units (MeV^2) (all internal calculations are in GeV)\nG4double G4ChipsKaonPlusElasticXS::GetExchangeT(G4int tgZ, G4int tgN, G4int PDG)\n{\n if(PDG!=321) G4cout<<\"*Warning*G4ChipsKaonPlusElasticXS::GetExT:PDG=\"<<PDG<<G4endl;\n if(onlyCS) G4cout<<\"*Warning*G4ChipsKaonPlusElasticXS::GetExT: onlyCS=1\"<<G4endl;\n if(lastLP<-4.3) return lastTM*GeVSQ*G4UniformRand();// S-wave for p<14 MeV/c (kinE<.1MeV)\n G4double q2=0.;", "\n if(tgZ==1 && tgN==0) // ===> p+p=p+p\n {\n G4double E1=lastTM*theB1;\n G4double R1=(1.-std::exp(-E1));\n G4double E2=lastTM*theB2;\n G4double R2=(1.-std::exp(-E2*E2*E2));\n G4double E3=lastTM*theB3;\n G4double R3=(1.-std::exp(-E3));\n G4double I1=R1*theS1/theB1;\n G4double I2=R2*theS2;\n G4double I3=R3*theS3;\n G4double I12=I1+I2;\n G4double rand=(I12+I3)*G4UniformRand();\n if (rand<I1 )\n {\n G4double ran=R1*G4UniformRand();\n if(ran>1.) ", "ran=1.;", "\n q2=-std::log(1.-ran)/theB1;\n }\n else if(rand<I12)\n {\n G4double ran=R2*G4UniformRand();\n if(ran>1.) ", "ran=1.;", "\n q2=-std::log(1.-ran);\n if(q2<0.) ", "q2=0.;", "\n q2=std::pow(q2,third)/theB2;\n }\n else\n {\n G4double ran=R3*G4UniformRand();\n if(ran>1.) ", "ran=1.;", "\n q2=-std::log(1.-ran)/theB3;\n }\n }\n else\n {\n G4double a=tgZ+tgN;\n G4double E1=lastTM*(theB1+lastTM*theSS);\n G4double R1=(1.-std::exp(-E1));\n G4double tss=theSS+theSS; // for future solution of quadratic equation (imediate check)\n G4double tm2=lastTM*lastTM;\n G4double E2=lastTM*tm2*theB2; // power 3 for lowA, 5 for HighA (1st)\n if(a>6.5)E2*=tm2; // for heavy nuclei\n G4double R2=(1.-std::exp(-E2));\n G4double E3=lastTM*theB3;\n if(a>6.5)E3*=tm2*tm2*tm2; // power 1 for lowA, 7 (2nd) for HighA\n G4double R3=(1.-std::exp(-E3));\n G4double E4=lastTM*theB4;\n G4double R4=(1.-std::exp(-E4));\n G4double I1=R1*theS1;\n G4double I2=R2*theS2;\n G4double I3=R3*theS3;\n G4double I4=R4*theS4;\n G4double I12=I1+I2;\n G4double I13=I12+I3;\n G4double rand=(I13+I4)*G4UniformRand();\n if(rand<I1)\n {\n G4double ran=R1*G4UniformRand();\n if(ran>1.) ", "ran=1.;", "\n q2=-std::log(1.-ran)/theB1;\n if(std::fabs(tss)>1.e-7) q2=(std::sqrt(theB1*(theB1+(tss+tss)*q2))-theB1)/tss;\n }\n else if(rand<I12)\n {\n G4double ran=R2*G4UniformRand();\n if(ran>1.) ", "ran=1.;", "\n q2=-std::log(1.-ran)/theB2;\n if(q2<0.) ", "q2=0.;", "\n if(a<6.5) q2=std::pow(q2,third);\n else q2=std::pow(q2,fifth);\n }\n else if(rand<I13)\n {\n G4double ran=R3*G4UniformRand();\n if(ran>1.) ", "ran=1.;", "\n q2=-std::log(1.-ran)/theB3;\n if(q2<0.) ", "q2=0.;", "\n if(a>6.5) q2=std::pow(q2,sevth);\n }\n else\n {\n G4double ran=R4*G4UniformRand();\n if(ran>1.) ", "ran=1.;", "\n q2=-std::log(1.-ran)/theB4;\n if(a<6.5) q2=lastTM-q2; // u reduced for lightA (starts from 0)\n }\n }\n if(q2<0.) ", "q2=0.;", "\n if(!(q2>=-1.||q2<=1.)) ", "G4cout<<\"*NAN*G4QKaonPlusElasticCS::GetExchT: -t=\"<<q2<<G4endl;\n if(q2>lastTM)\n {\n q2=lastTM;\n }\n return q2*GeVSQ;\n}\n\n// Returns B in independent units (MeV^-2) (all internal calculations are in GeV) see ExT\nG4double G4ChipsKaonPlusElasticXS::GetSlope(G4int tgZ, G4int tgN, G4int PDG)\n{\n if(onlyCS)G4cout<<\"*Warning*G4ChipsKaonPlusElasticXS::GetSl:onlCS=true\"<<G4endl;\n if(lastLP<-4.3) return 0.; ", " // S-wave for p<14 MeV/c (kinE<.1MeV)\n if(PDG !", "= 321)\n {\n G4ExceptionDescription ed;\n ed << \"PDG = \" << PDG << \", Z = \" << tgZ << \", N = \" << tgN\n << \", while it is defined only for PDG=321 (K+)\" << G4endl;\n G4Exception(\"G4ChipsKaonPlusElasticXS::GetSlope()\", \"HAD_CHPS_0000\",\n FatalException, ed);\n }\n if(theB1<0.) ", "theB1=0.;", "\n if(!(theB1>=-1.||theB1<=1.))G4cout<<\"*NAN*G4QKaonPlusElCS::GetSlope:B1=\"<<theB1<<G4endl;\n return theB1/GeVSQ;\n}\n\n// Returns half max(Q2=-t) in independent units (MeV^2)\nG4double G4ChipsKaonPlusElasticXS::GetHMaxT()\n{\n return lastTM*HGeVSQ;\n}\n\n// lastLP is used, so calculating tables, one need to remember and then recover lastLP\nG4double G4ChipsKaonPlusElasticXS::GetTabValues(G4double lp, G4int PDG, G4int tgZ,\n G4int tgN)\n{\n if(PDG!=321)G4cout<<\"*Warning*G4ChipsKaonPlusElasticXS::GetTaV:PDG=\"<<PDG<<G4endl;\n\n //AR-24Apr2018 Switch to allow transuranic elements\n const G4bool isHeavyElementAllowed = true;\n if(tgZ<0 || ( !", "isHeavyElementAllowed && tgZ>92))\n {\n G4cout<<\"*Warning*G4QKaonPlusElasticCS::GetTabV:(1-92)NoIsotopes for Z=\"<<tgZ<<G4endl;\n return 0.;", "\n }\n G4int iZ=tgZ-1; // Z index\n if(iZ<0)\n {\n iZ=0; // conversion of the neutron target to the proton target\n tgZ=1;\n tgN=0;\n }\n G4double p=std::exp(lp); // momentum\n G4double sp=std::sqrt(p); // sqrt(p)\n G4double p2=p*p; \n G4double p3=p2*p;\n G4double p4=p3*p;\n if ( tgZ == 1 && tgN == 0 ) // KaonPlus+P\n {\n G4double dl2=lp-lastPAR[11];\n theSS=lastPAR[34];\n theS1=(lastPAR[12]+lastPAR[13]*dl2*dl2)/(1.+lastPAR[14]/p4/p)+\n (lastPAR[15]/p2+lastPAR[16]*p)/(p4+lastPAR[17]*sp);\n theB1=lastPAR[18]*std::pow(p,lastPAR[19])/(1.+lastPAR[20]/p3);\n theS2=lastPAR[21]+lastPAR[22]/(p4+lastPAR[23]*p);\n theB2=lastPAR[24]+lastPAR[25]/(p4+lastPAR[26]/sp); \n theS3=lastPAR[27]+lastPAR[28]/(p4*p4+lastPAR[29]*p2+lastPAR[30]);\n theB3=lastPAR[31]+lastPAR[32]/(p4+lastPAR[33]); \n theS4=0.;", "\n theB4=0.; ", "\n // Returns the total elastic pim-p cross-section (to avoid spoiling lastSIG)\n G4double dp=lp-lastPAR[4];\n//G4cout<<\"lastPAR[8] \"<<lastPAR[8]<<\" lastPAR[9] \"<<lastPAR[9]<<\" lastPAR[10] \"<<lastPAR[10]<<G4endl; \n return lastPAR[0]/(lastPAR[2]+sqr(p-lastPAR[1]))+(lastPAR[3]*dp*dp+lastPAR[5])/\n (1.-lastPAR[6]/sp+lastPAR[7]/p4)\n +lastPAR[8]/(sqr(p-lastPAR[9])+lastPAR[10]); // Uzhi\n\n }\n else\n {\n G4double p5=p4*p;\n G4double p6=p5*p;\n G4double p8=p6*p2;\n G4double p10=p8*p2;\n G4double p12=p10*p2;\n G4double p16=p8*p8;\n //G4double p24=p16*p8;\n G4double dl=lp-5.;", "\n G4double a=tgZ+tgN;\n G4double pah=std::pow(p,a/2);\n G4double pa=pah*pah;\n G4double pa2=pa*pa;\n if(a<6.5)\n {\n theS1=lastPAR[9]/(1.+lastPAR[10]*p4*pa)+lastPAR[11]/(p4+lastPAR[12]*p4/pa2)+\n (lastPAR[13]*dl*dl+lastPAR[14])/(1.+lastPAR[15]/p2);\n theB1=(lastPAR[16]+lastPAR[17]*p2)/(p4+lastPAR[18]/pah)+lastPAR[19];\n theSS=lastPAR[20]/(1.+lastPAR[21]/p2)+lastPAR[22]/(p6/pa+lastPAR[23]/p16);\n theS2=lastPAR[24]/(pa/p2+lastPAR[25]/p4)+lastPAR[26];\n theB2=lastPAR[27]*std::pow(p,lastPAR[28])+lastPAR[29]/(p8+lastPAR[30]/p16);\n theS3=lastPAR[31]/(pa*p+lastPAR[32]/pa)+lastPAR[33];\n theB3=lastPAR[34]/(p3+lastPAR[35]/p6)+lastPAR[36]/(1.+lastPAR[37]/p2);\n theS4=p2*(pah*lastPAR[38]*std::exp(-pah*lastPAR[39])+\n lastPAR[40]/(1.+lastPAR[41]*std::pow(p,lastPAR[42])));\n theB4=lastPAR[43]*pa/p2/(1.+pa*lastPAR[44]);\n }\n else\n {\n theS1=lastPAR[9]/(1.+lastPAR[10]/p4)+lastPAR[11]/(p4+lastPAR[12]/p2)+\n lastPAR[13]/(p5+lastPAR[14]/p16);\n theB1=(lastPAR[15]/p8+lastPAR[19])/(p+lastPAR[16]/std::pow(p,lastPAR[20]))+\n lastPAR[17]/(1.+lastPAR[18]/p4);\n theSS=lastPAR[21]/(p4/std::pow(p,lastPAR[23])+lastPAR[22]/p4);\n theS2=lastPAR[24]/p4/(std::pow(p,lastPAR[25])+lastPAR[26]/p12)+lastPAR[27];\n theB2=lastPAR[28]/std::pow(p,lastPAR[29])+lastPAR[30]/std::pow(p,lastPAR[31]);\n theS3=lastPAR[32]/std::pow(p,lastPAR[35])/(1.+lastPAR[36]/p12)+\n lastPAR[33]/(1.+lastPAR[34]/p6);\n theB3=lastPAR[37]/p8+lastPAR[38]/p2+lastPAR[39]/(1.+lastPAR[40]/p8);\n theS4=(lastPAR[41]/p4+lastPAR[46]/p)/(1.+lastPAR[42]/p10)+\n (lastPAR[43]+lastPAR[44]*dl*dl)/(1.+lastPAR[45]/p12);\n theB4=lastPAR[47]/(1.+lastPAR[48]/p)+lastPAR[49]*p4/(1.+lastPAR[50]*p5);\n }\n // Returns the total elastic (n/p)A cross-section (to avoid spoiling lastSIG)\n G4double dlp=lp-lastPAR[4]; // ax\n // p1 p2 p3 p4\n return (lastPAR[0]*dlp*dlp+lastPAR[1]+lastPAR[2]/p2)/(1.+lastPAR[3]/p2/sp);\n }\n return 0.;", "\n} // End of GetTableValues\n\n// Returns max -t=Q2 (GeV^2) for the momentum pP(GeV) and the target nucleus (tgN,tgZ)\nG4double G4ChipsKaonPlusElasticXS::GetQ2max(G4int PDG, G4int tgZ, G4int tgN,\n G4double pP)\n{\n G4double pP2=pP*pP; // squared momentum of the projectile\n if(tgZ || tgN>-1) // ---> pipA\n {\n G4double mt=G4ParticleTable::GetParticleTable()->GetIonTable()->GetIon(tgZ,tgZ+tgN,0)->GetPDGMass()*.001; // Target mass in GeV\n\n G4double dmt=mt+mt;\n G4double mds=dmt*std::sqrt(pP2+mK2)+mK2+mt*mt; // Mondelstam mds\n return dmt*dmt*pP2/mds;\n }\n else\n {\n G4ExceptionDescription ed;\n ed << \"PDG = \" << PDG << \",Z = \" << tgZ << \", N = \" << tgN\n << \", while it is defined only for p projectiles & Z_target>0\" << G4endl;\n G4Exception(\"G4ChipsKaonPlusElasticXS::GetQ2max()\", \"HAD_CHPS_0000\",\n FatalException, ed);\n return 0;\n }\n}\n" ]
{ "pile_set_name": "Github" }
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[ "Joker updates - 2017\n\nSign Up Log In Messenger Facebook Lite Mobile Find Friends People Pages Places Games Locations Celebrities Marketplace Groups Recipes Moments Instagram About Create Ad Create Page Developers Careers Privacy Cookies Ad Choices Terms Help Settings Activity Log. ", "Looks like you put weight on.. He says no, it's just thing that bother him - but then he think about how he feels when he's around her, and the little things she does, and it becomes irrelevant. ", "Text in the box: The contestants on there are always so bad, so Janelle would probably fit it with that haha. ", "There's only eleven and a half left! ", "Alex gets called to DR - Jason sends her off with a fart, and she slaps him several times. ", "Christmas and Alex silently laugh hard. ", "Posted on September 20, September 20, by California Coaster Kings. ", "Jason says he's going to hear everything now and wake up every 3 seconds from paranoia.", "\n\nJoker updates Video\n\nMega64 Podcast 354 - Joker Update 06.07.15 He says no wonder his wife keeps the gun at night. ", "Jason called to the DR. ", "Head writer Slot games star Sussman and consultant Kay Alden both exiting. ", "I can't believe they've never redesigned it. ", "On the backs of these cranes are piles of wood, as well as what appear to be green mobile casino slots real money boxes. ", "James morrison derby, the design is blackwing quasar and terrible, even by standards or whenever it was a casino software. ", "It appears Jason may be first to have risen. ", "Or just wynn casino host email us here; info poker betrugen. ", "SHe asks if he's going to tell her whatever he was going to tell. ", "I'm a Janelle fan, but acting is not her strong suit and the fact that people smart live casino that blackjack strategie hilarious. ", "I am in this category. ", "She was a huge gold-digger, obsessed with qr code reader free and wealth, making her appear very surface to me in addition to her extensive read devil surgery. ", "Leave a Reply Cancel reply Your email address will not be published. ", "With the recent addition of Twisted Colossus, most Californian coaster enthusiasts know the euphoria that RMC delivers, and we were there every step of the construction process to keep you up to date. ", "He says yes but he just wants to enjoy this moment for a minute - says it's been so long. ", "Why golden buzzers for singers? ", "It wasn't until BB15 when the racism made headlines that I decided to tune back in to see what was going on. ", "BigBrother submitted 4 months ago by TheZanyCat.", "\n\nMuss: Joker updates\n\nMilagro club casino no deposit bonus code\n\n447\n\nJoker updates\n\n441\n\nCLUB GOLD CASINO BONUS CODE 2017\n\n665\n\nJoker updates\n\n108\n\nLeauge of legends na\n\nAlso in the area between the first turnaround and Roulette pro bot download are incredibly large stacks stersgsme fresh RMC wood schach spiel online CA site. ", "Elena came over in Mark's bed to give him a hug. ", "I don't have a problem with her wanting plastic surgery. ", "Try our regular chat HERE use Java if unable to connect Heads to BA area and knocks on WC door prior to entering. ", "Seiten zum spielen won the 2nd Temptation competition safety, Mr bin deutsch came last wertkartenverkauf sicher is the 3rd nom. ", "Email or Phone Password Forgot account?", "\n\nTwo large RMC cranes sit inside the structure, both of which have been working hard to remove track. ", "Also, it's getting a little tougher to access BBCAN from the U. He keeps smacking and scratching himself when he feels touches. ", "They've eaten three pieces of ham, a piece of cheese, chocolate milk, a cranberry juice and go to bed. ", "Two, the mods were very VERY biased towards particular HG's. ", "Or just simply email us here; info californiacoasterkings." ]
{ "pile_set_name": "Pile-CC" }
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[ "What Does “Eating Frogs” Have To Do With Improving Your Productivity?", "\n\nThis is a follow up to a previous article about beating procrastination, How To Beat Procrastination When You Don’t Know What To Do Next. ", "This is a hot topic if you are running your own entrepreneurial business and largely responsible for getting things done. ", "Combine this with the current online world with so many distractions being just a mouse click away.", "\n\nImportance Of Prioritizing Tasks\n\nI am the first to admit there is no shortage of things to be done. ", "Seriously, who’s “to do” list isn’t overflowing? ", "Famous motivational speaker Brian Tracey says that you will always have things on your to do list and you will never get them all done. ", "Thanks for the vote of confidence Brian! ", "No, in all seriousness, Brian is onto something. ", "There are never enough hours in the day to get all the tasks done that we want to get done, especially if you are running a business.", "\n\nKnowing that your to do list is a never ending saga, what Brian suggests doing is prioritizing the list. ", "I know it sounds so obvious and simple, but you would be surprised how many people make to do lists filled with meaningless and irrelevant junk when they have serious issues to sort out with their business.", "\n\nI know it may seem ridiculous when illustrated like this but don’t laugh. ", "The harsh reality is with limited time and so much to do, if you want to make your business work and take it to the next level, you will need to understand that not all your tasks are going to get done. ", "I am not suggesting you become a hermit who lives in a pigsty and never speaks to anyone. ", "I am just saying at the end of the day you need to know you have accomplished your most important tasks. ", "And that can either be having a successful business or having a cobweb free home, which would you rather?", "\n\nMake out your to do list the day before, either as the last part of that day’s work or before you go to bed. ", "This way you can really put some thought into what is really important and what needs to get done, and then you are ready to get started on it the next day.", "\n\nAnother way to look at how to prioritize your tasks and what to put at the very top of your to do list is to ask yourself this question: “If I was only allowed to do one task today, would I be satisfied that I got this one task done?” ", "When you look at managing your time like this you can really start to re-prioritize your to do list and get a clear idea of what is most important for growing your business. ", "If you are still struggling with prioritizing your list, I will make it really easy for you: What task do you need to do today that will make your business money?", "\n\nBreak Your Tasks Down\n\nFor those looking for more specific Internet business time management advice, you can’t beat Internet marketer, time management specialist and author of Double Your Productivity for LifeJason Fladlien.", "\n\nJason likes to break tasks down into simple and easy to digest components. ", "He feels the brain is only capable of handling seven bits of information plus or minus two bits. ", "So based on this he takes complicated and often overwhelming tasks such as writing sales copy and breaks it into seven components. ", "Now the task just becomes seven easy to follow steps.", "\n\nThis is how Jason was able to create 30+ products in a few months and quickly make a mark in the Internet marketing scene. ", "I highly recommend you grab his FREE report (no-optin) Time Management Secrets of a Madman.", "\n\nGet Important Things Done First\n\nBuilding on prioritizing the to do list, I am a big fan of doing the hard and important tasks first thing in the morning when I am mentally freshest. ", "I have my to do list from the night before, so there is no guessing or fiddling around in the morning.", "\n\nLegendary copywriter Gary Bencivenga was a big fan of doing a good three hour block of writing in the morning. ", "A phone off the hook, lock the door, no disturb sign on the door type of three hour block. ", "He knew that this block was super productive because he wasn’t tired and he was totally focused. ", "He knew that if he got that three hour block out of the way that he had a productive day and anything else he got done was a bonus. ", "He also realized that a focused three hour block was often more productive than an interrupted normal eight hour work day.", "\n\nTake Control Of Your Time And Be Non-Reactive\n\nWhen you are most mentally alert in the morning and you still have some mental fuel in the tank, do not go wasting it on checking email and surfing the net. ", "Take charge of your time and focus. ", "You can decide what you should spend your time and energy on. ", "If the first thing you do is open your email, then you have gone straight into a reactive mode where other people are dictating where your thoughts and energies go.", "\n\nTim Ferriss has talked extensively about email management and recommendations of just checking email twice a day. ", "If you find you also don’t have the self-discipline to refrain from browsing and wasting time then you may want to check out another Ferriss recommendation called rescue time. ", "This great piece of software allows you to block websites, but it will also monitor your browsing activity, which can be a real eye opener.", "\n\nOnce you see that you are spending three hours of your work day reading forums instead of actually working, you may just realize how much time you are wasting.", "\n\nConclusion\n\nI do not want to come across as a slave master for your business. ", "But I guess the bottom line is: we all want our businesses to be as successful as possible. ", "Besides discussing marketing strategies, I often spend time with my marketing clients helping them get a clearer picture in their head about exactly how their business is going to make money. ", "With this picture in mind, it now becomes easier to prioritize their daily tasks and know what needs to get done now and what can wait.", "\n\nDear Leevi – Nice and refreshing post. ", "I would like to add the 5 D method as mentioned by Brain Tracy in his book. ", "It states that before doing any task, we should check 5 Ds i.e.\n1. ", "Don’t Do it\n2. ", "Delay it\n3. ", "Delegate it\n4. ", "Dissect it\n5. ", "Do it with delight!", "\n\nA great follow up to your last article Leevi. ", "I would like to share my view on a different angle this time. ", "I am sure some entrepreneurs have days when they simply cannot focus, even with an aid of a list.", "\n\nSometimes we do have to acknowledge that we are human beings, take a break and frequently, a cup of tea is all it takes to snap us out of fidgeting and getting nowhere.", "\n\nAlso, the art of delegation is worth learning. ", "So if resources allow, having people on board will accomplish more for your business rather than trying to do it all by yourself whilst you and your business suffer from lack of productivity and drive to succeed.", "\n\nChecking your email again and again can affect productivity in large way. ", "Because there is so much of distraction in your inbox, that you start to loose focus on the things that you are supposed to you.", "\n\nI write a lot of to do lists but find it difficult to finish these tasks. ", "I am slowly improving this nowadays. ", "Hope to continue improving.", "\n\nThe question ‘How my Business is Going to Make Money’ is an interesting one, and I do think that the answers to that question isn’t that complicated:\n\nBy finding locations on the Internet where I can find like-minded people – like for example somebody like – You – reading this Blog. ", "Somebody like – you – that definitely will also like reading the posts you can find on– The Home Business Lifestyle – Blog, Because on it you will discover interesting posts and other Resources that can be helpful for you Home Business.", "\n\nWriting it in such a way that you like it so much that you actually like to bookmark it, and like to Re-visitfrequently,\n\n(See one of the posts that ‘Pop-up’\nin the – Most Popular-widget – titled:\n\nI agree with Jane – start with the worst job first and leave the best for last. ", "Also, don’t leave things until the deadline looms.", "\nI wrote a post about using project lists instead of a daily to do list as this works quite well for me. ", "Within each project I have a list of tasks that are related to that project. ", "Every day I will choose which project to work on and that way I get to focus on what I want to do, while at the same time making progress with a project.", "\nThanks for a great post.", "\n\nThis is very timely for me Leevi. ", "I would always have stickies of to do things but when something came up and I begin to take interest in it ( like a news feed) I always fail to follow what I have scheduled. ", "Thanks for the tips!", "\n\nI always try to set the priority but my task list continues to grow and at time its difficult for me to do my work according to priority list. ", "And many times it happen that I use to sit at night to complete my pending work.. I am not complaining but sometimes this thing hurts me a lot when my work didn’t show me any positive output." ]
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[ "WORKPLACE HEALTH & SAFETY\n\nObadare undertakes every order with a safety culture underpinned by our company’s daily mission of ‘No injuries to anyone’.", "\n\nOur policies maintain the central theme that all incidents are preventable and that safety is responsibility of each and every person. ", "With this in mind, our values-based approach to our work begins with the leadership team and is continuously reinforced across our business. ", "All senior managers actively participate in the operational safety functions.", "\n\nThis strong and clearly demonstrated leadership, combined with effective training and awareness programs, reflects the value placed on safety throughout our workshop and field teams, subcontractors and office support staff. ", "We believe this to be essential in ensuring that our people and the communities in which we operate, remain free from injury or illness.", "\n\nWe actively strive for continuous improvement.", "\n\nWe partner with our clients and sub contractors alike, to identify and implement industry best-practice to ensure we remain at the forefront of the industry.", "\n\nWe set high standards for leading indicators such as inspections, audits and task observation and interaction processes.", "\nThis, combined with rigorous near-miss reporting, enables us to establish additional control measures to effectively pre-empt any potential harm.", "\n\nOur safety systems, though exacting, are able to successfully adapt to the particular requirements of every project and client. ", "This means that we are able to meet our clients’ expectations for timely and efficient delivery whilst maintaining maximum safety.", "\n\nAs a result, we approach each task with a full awareness of the potential risks and with realistic strategies in place to mitigate those risks.", "\n\nRegardless of the location or work methodology, our attention to workmanship does not compromise the safety of our people. ", "We maintain that no task is so important or urgent that it cannot be undertaken safely." ]
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[ "Image copyright AP Image caption Sandy Phan-Gillis was detained while trying to travel to Macau\n\nAn American woman held in China since last year has been charged with espionage, according to China's foreign ministry.", "\n\nSandy Phan-Gillis, 56, was first detained in March 2015 while in China as part of a US trade delegation.", "\n\nHer husband, Jeff Gillis, said the charges were \"absolutely false\" and called for her release.", "\n\nThe news comes ahead of President Barack Obama's visit to China for a G20 summit in Hangzhou.", "\n\nThe president is scheduled to meet his Chinese counterpart Xi Jinping on Saturday amid heightened tensions between the US and China over Beijing's territorial claims in the South China Sea as well as cyber hacking.", "\n\nImage copyright SaveSandy.org Image caption The delegation travelled across China, including Beijing and Shenzhen, a sister city of Houston\n\nMs Phan-Gillis, a Texan businesswoman who is of Chinese ancestry and is a naturalised US citizen, travelled to China to promote business opportunities in her hometown of Houston.", "\n\nShe was detained while trying to travel to Macau from the southern city of Zhuhai.", "\n\nIn June, a UN panel ruled that China had violated international human rights by denying her access to legal assistance and holding her without bringing her before judicial authorities.", "\n\nA State Department official told Reuters the US remains \"deeply concerned\" about Ms Phan-Gillis and has \"repeatedly pressed\" Chinese authorities to provide more information on the case.", "\n\nThe US consulate in Guangzhou has provided consular assistance to Ms Phan-Gillis, which includes monthly visits, according to the State Department official.", "\n\nMr Gillis said his wife was accused of travelling to China on a spy mission in 1996, but her passport shows that she did not make a trip to the country during that period of time.", "\n\nMs Phan-Gillis has denied any wrongdoing and said her detention was political and not criminal, according to a letter transcribed by a US consular official in China." ]
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[ "Q:\n\nDo I still Need To Use Prepared Statement\n\nUsing PHP and MySQLi I have a simple form with 4 HTML 5 Dropdown Select list inputs. ", "Now wondering do I still have to use Prepared Statement to secure my database? ", "Am I still in the risk of SQL Injection issues? ", "Or is there any other type of risk for using this type of inputs. ", "Thanks\n\nA:\n\nYou are still wide open for an injection attack since the value inserted through your select box could easly be modifed by the end user. ", "\nIf you have a good validation server side, then doing it without prepared statement would work. ", "\nWith good i mean something like this: \n$array = Array(\"all\", \"your\", \"possible\", \"values\", \"from\", \"Select boxes\");\nif(in_array ($_POST['selectbox'], $array)){\n //Mysql statements etc....\n}\n\nDirectly inserting user input is NEVER a good idea. ", "You should never trust the end user!", "\n\n" ]
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[ "Whenever the first games of the Gabe Kapler Era are played, Giants fans might have to get used to a couple of new ideas.", "\n\nKapler and his staff intend to use openers, which the Giants did just once under Bruce Bochy, and they also have made it clear that they don't necessarily believe in naming a closer. ", "They may rotate several pitchers into the ninth inning, and Kapler started laughing Tuesday when asked during an interview on KNBR if there were young pitchers who stood out to him in camp as potential openers or closers.", "\n\n\"I'm laughing because I think it's the same dude,\" Kapler said. \"", "I think Rogers would be a really interesting guy to open up a game and go through five, six, seven batters left and right, and I also think he would be an interesting candidate to shut down a couple of right-handed and left-handed hitters in a row. ", "I think whenever you're thinking about a guy who can close down a baseball game and a guy who can open a baseball game, you don't want them to be specialists, right?\"", "\n\nTyler Rogers was one of the standouts of camp, building on a strong call-up last September. ", "The submarining right-hander allowed just two earned runs in 17 appearances last year and was cruel to hitters on both sides. ", "Righties hit .209 against him and lefties were just 3-for-22 (.136) with no extra-base hits.", "\n\nRogers, 29, came to camp as part of a wide-open competition in the bullpen jobs. ", "Pretty early on it was apparent that he was one of the better arms in the group, and the staff talked often of the kind of impact he could make late in games. ", "If the season had started on time, Rogers and Trevor Gott stood as two obvious ninth-inning options with veteran Tony Watson dealing with a shoulder issue.", "\n\n\"What Rogers demonstrated in camp is that he's going to be able to get righties and lefties out,\" Kapler told KNBR. \"", "And lefties, specifically, he worked on a slider that he throws up and under the hands of a left-handed hitter. ", "It's kind of unusual from that really low arm angle, that submarine style, for a guy not to rely on his sinker and slider to be down in the zone, but he can fire it up at that angle. ", "His sinker, his two-seamer, acts like a curveball, so it's another unique pitch to get left-handers out.\"", "\n\nFirst career strikeout for Tyler Rogers. ", "I have no idea what this pitch is: pic.twitter.com/Sk8WmugDQJ — Alex Pavlovic (@PavlovicNBCS) August 31, 2019\n\nKapler mentioned that Rogers had \"one of the more impressive live BP sessions in camp,\" referencing a day early in camp where hitters were unable to even put the ball in play. ", "Veteran catcher Rob Brantly was among those who faced Rogers that day and he yelled \"progress!\" ", "to teammates when he popped one pitch up.", "\n\n[RELATED: Looking back at day Giants ended camp]\n\nThat was a moment when it was clear that Rogers had carried his 2019 momentum over. ", "Whenever baseball resumes, the new staff plans to keep throwing him out there in bigger and bigger spots.", "\n\n\"He'd be an exciting candidate to take down both of those roles,\" Kapler said. \"", "I'm not saying he would be that guy, but I think he would be an exciting candidate.\"" ]
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[ "1. ", "Field of the Invention\nThe invention relates to an apparatus for adjusting the toe angle of a wheel, and more particularly, to an apparatus capable of adjusting the wheel toe according to the travelling condition of a vehicle so as to improve the controllability of the vehicle.", "\n2. ", "Description of the Related Art\nA car body of an automobile is supported by suspension elements to which wheels are attached. ", "These suspension elements are variously devised to improve stability during travelling.", "\nFor example, as disclosed in Japanese Patent Public Disclosure (KOKAI) No. ", "15345/80, the caster, chamber and toe angle in the suspension for a front wheel are set to proper values in order to improve the controllability in steering. ", "Thus, the vehicle performance may be adequate with respect to straight line stability, while it may smoothly make a turn. ", "The front wheels also may return naturally to the straight drive position after turning.", "\nHowever, in order to improve controllability during high speed travelling of the vehicle, it is necessary to improve the straight line stability of the vehicle, which is contradictory to the controllability in turning. ", "Therefore, an apparatus for setting a rear wheel to toe-in has been proposed (for example, as shown in Japanese Patent Public Disclosure (KOKAI) No. ", "214470/83). ", "Thus, the straight line stability during high speed travelling of the vehicle may be improved.", "\nAccording to the apparatus noted above, however, problems are encountered since the structure of the apparatus is complicated, and the unsprung weight is increased since the apparatus is provided on an arm portion for supporting the wheel.", "\nA steering gear of a vehicle described in the Japanese Utility Model Public Disclosure (KOKAI) No. ", "15051/85 relates to an apparatus for steering a wheel of a vehicle provided with two suspension arms extending widthwise of a car body and a carrier connected to respective outer ends of the suspension arms for supporting the wheel. ", "The apparatus includes an arm to which an inner end of one of the suspension arms is pivotably connected about a horizontal axis, the arm being movable in the lateral direction of the car body, and an actuator for moving said arm. ", "An inner end of the other suspension arms is pivotably connected to the car body about the horizontal axis.", "\nSince the steering gear has one inner end of one of the suspension arms pivotably connected to the arm only about the horizontal axis, that is, the inner end of said arm moves two-dimensionally, an adjusting range of the toe angle of the wheel is relatively small." ]
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[ "In recent years, various stem cells and many methods of inducing their differentiation into somatic cells have been discovered, and therefore tissue engineering has been intensively focused as a novel medical treatment that takes the place of organ transplantation. ", "This technology aims at in vivo or in vitro construction of organs directly used for treatments of humans, and the technology has realized many techniques of expressing organ-like functions in vitro. ", "Thus, the technology is expected to provide high throughput (HTS) cell evaluation systems that can be used for pharmacological experiments without preparation of organs, per se, and can cope with an enormous number of tests in researches for drug design, diagnosis and the like. ", "Further, the technology is also expected as a novel technology that enables substance production unique to mammalian cells.", "\nAnalysis of human DNA nucleotide sequences by the human genome project has been almost completed, and researches in this field have been moving to post-genomic researches using that information. ", "An example is a tailor-made medicament, which is a frequent article on recent newspaper. ", "The researches are expected to yield enormous markets of medicaments, and support tools for drug design and medication. ", "DNA chips and protein chips have been currently focused as such tools, and many companies including American venture business entities are in fierce competition.", "\nHowever, the number of the human genes reported by the human genome project is about 30,000 to 40,000, which is not so larger compared with the number of 13,000 in fly, and there are also many homologous genes over species. ", "Therefore, it has been becoming clear that individuality of species cannot be determined solely based on DNA. ", "Human genetic information is used for cell construction starting from DNA via RNA to proteins in accordance with the central dogma. ", "Transmission of the information is not one-way, but consists of a nonlinear system including many interactions and feedback systems, i.e., a so-called complex system. ", "In life entities, there is a mechanism imparting stability and robustness thereto. ", "For example, in the liver, a different expression system will function depending on a state of fasting, satiety, and drinking, although a gene, cells and tissues are identical. ", "Therefore, in order to elucidate life phenomena, it is attempted to understand a life entity as a system, not merely to focus on molecular reactions, and study by simulation on the basis of boundary conditions that can be obtained by analyzing cells and organs in vivo. ", "This new technical field is called a bio-system engineering, which has rapidly been focused.", "\nIn order to accurately understand life phenomena, it is necessary to handle systems of at least a cellular level or higher, and for this purpose, a tool is desired in which cells or tissues are arrayed while their native functions are maintained. ", "Thus, researches for methods of constructing cell arrays have become active. ", "Specifically, methods of controlling hydrophilicity or hydrophobicity of a surface of solid substrate such as glass substrate by using lithography are known (S. N. Bhatia et al, Biotecnol. ", "Prog., ", "14, 378 (1998); Toshihiro Akaike et al., ", "Japanese Patent Unexamined Publication (KOKAI) No. ", "5-176753; Otsuka et al, 30th Biomedical Polymer Symposium, Lecture Summaries, page 9 (2001); Kikuchi et al, 30th Biomedical Polymer Symposium, Lecture Summaries, page 35 (2001) and the like). ", "However, these methods require expensive apparatuses for lithography, and also have a problem in that carriers for cell culture cannot be prepared conveniently.", "\nA water-containing polymer gel has a structure similar to that of a living body, and has a property of expanding or shrinking depending on external conditions such as temperature, acidity, and alkalinity. ", "Accordingly, applications in the medical field, including a use as an artificial organ or tissue such as an artificial muscle or encapsulation of a drug therein to control an amount to be released, have been attempted, as well as applications as an anchorage of cell growth in a cell culture as a gel containing various kinds of cytokines and the like.", "\nIt is known that cells are arrayed with polarity when they form a tissue in a living body. ", "For example, hepatocytes absorb blood components from the vascular endothelial cell side, and excrete metabolites such as bile acid from the opposite side. ", "Since this bile acid has potent cytotoxicity, cell culture by adhering the cells on an impermeable support such as glass suffers from a problem that stable long-term culture is difficult. ", "Although it is known that the polarity of cells is expressed by stimulation given from one way to the cells, cell culture by adhering the cells on an impermeable support raises a problem that stimulation cannot be given from the adhesion side. ", "Further, in order to perform lithography, a photosensitive solution needs to be applied beforehand. ", "However, a substance-permeable support will cause a problem that the photosensitive solution as well as reaction products and developing/fixing solutions permeate into the support, and toxicity or stimulation is given to cultured cells due to denaturation of the support, remaining of compounds in the support or the like.", "\nTo solve these problems, a permeable collagen membrane for cell culture, MEN-01, is sold by KOKEN CO., ", "LTD. ", "as a cell culture material for culturing cells with different media for the both sides of the cells. ", "However, in this cell culture material, the collagen membrane is much swelled with a medium, and thus the material is significantly distorted during the culture. ", "Therefore, it is difficult to observe a culture state of cells. ", "In Japanese Patent Unexamined Publication (KOKAI) No. ", "2001-120267, a carrier for cell culture is proposed which comprises a porous membrane together with an alginic acid gel layer and an extracellular matrix component gel layer or an extracellular matrix component sponge layer which are laminated on the porous membrane. ", "However, this carrier for cell culture has a microfilter layer, and therefore, growth state of cells cannot be observed under an optical microscope." ]
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[ "With Maryland dismantled and a trip to Michigan State on tap, Urban Meyer joined Paul Keels and Jim Lachey on 97.1 The Fan to talk Buckeye football.", "\n\nMeyer on what's up today: \"Just preparing for Michigan State.\"", "\n\nOn fast starts: \"Credit to our defense, but also offensively.\" ", "They've scored on opening drives in the last two weeks.", "\n\nCurtis Samuel's football IQ continues to \"amaze\" Meyer. ", "Samuel does so much offensively, he can't work on the fundamentals of WRs and RBs. ", "Samuel mostly works with Zach Smith and the receivers, however.", "\n\nDemario McCall's name \"comes up quite often because people love him.\" ", "He still has a \"ways to go\" but he's \"going to be good here,\" which is the stance Meyer has taken the last few weeks.", "\n\nCOFFEE WITH THE COACH QUESTION FROM DALE IN PAINESVILLE: What is the gameday routine for a noon game on the road?", "\n\n\"First of all, he's from Painesville, which is God's country up there.\"", "\n\n\"The routine changes a bit. ", "You gotta get them up and get them going.\"", "\n\n\"You certainly change your routine. ", "You don't have all the walk throughs.\"", "\n\n\"This time of year, I like it better that way. ", "Let's go.\"", "\n\nOffensive line is coming together. ", "Every single member of the line drew praise from Meyer for their play in recent weeks. ", "Elflein in particular: \"That news, when Pat said he's coming back—we have a chance. ", "If he doesn't come back, we're not very good.\"", "\n\nRed zone, first down, third down... it all falls on the offensive line. ", "That's why they fly first class and eat first class.", "\n\nOn red zone defense: \"It's almost deflating when you kick a field goal on offense. ", "It's a win when you make them kick a field goal on defense.\"", "\n\nKerry Coombs \"found Tyler Durbin somehow.\" ", "Meyer loves the former soccer player. ", "He's all in. \"", "And I don't normally like kickers.\"", "\n\nOn receivers: \"Two weeks in a row, not good, dominant.\" ", "Blocking especially, which is critical. \"", "Last two weeks we gave the game ball to Zone-6. ", "Not sure what Zone-6 means, but it's cool.\"", "\n\nCurtis Samuel is \"as good a blocker as we've ever had.\"", "\n\nKeels noted Noah Brown has been making plays. \"", "Not enough,\" Meyer said.", "\n\nOn Michigan State:\n\n\"Michigan State is Michigan State. ", "Excellent players and excellent coached.\"", "\n\nL.J. Scott, an Ohioan, is a \"guy they know well.\"", "\n\nNo difference in MSU defense since Pat Narduzzi.", "\n\nHow much film has he watched from last year? \"", "Zero. ", "Never could watch it.\"", "\n\nLUCAS IN MARYSVILLE: [Rambling question he read off a notecard.]", "\n\nMonday, Tuesday, Wednesday are about preparation.", "\n\nMeyer later visits with key players to get the pulse of the team.", "\n\nAlso meets with strength coach Mickey Marotti to make sure players are \"taking care of themselves.\"", "\n\nSleep is an important part of that. ", "Meyer personally does the bed checks. ", "The team will be in bed by 9:30 p.m. for a noon game.", "\n\nCRAIG IN CANTON: To what do you attribute the quickness of the defense?", "\n\n\"Let's wait until after Saturday to ask that,\" Meyer joked.", "\n\nCredited his players for their hard work primarily, coaching recruiting secondarily. \"", "If you take away those good players, suddenly they're not good coaches.\"", "\n\nOn putting J.T. Barrett under center for a few snaps: Meyer stole it from Wisconsin. ", "The jet sweep \"happens so much faster that way than the other way. ", "And you can't see the ball.\" ", "Realized it could be quite the weapon with Curtis Samuel.", "\n\nWalk-on linebacker Joe Burger is \"fine.\"", "\n\nCHRIS IN NEW ALBANY: Would you pass on a five-star recruit if they didn't have the leadership or displayed character red flags? ", "Have you ever thought about Noah Brown at tight end?", "\n\n\"At my age than now, more than ever. ", "We have walked away from some good players that wanted to come.\"", "\n\nMeyer cited \"social media\" and \"past experiences\" as big reasons he walks away.", "\n\n\"That doesn't mean you'll recruit all choir boys. ", "Not everybody is perfect. ", "Everybody makes mistakes.\"", "\n\nWill not move Brown to tight end, either. ", "He's too versatile as a receiver and \"good at what he does.\"", "\n\nRecruiting is a round-the-clock endeavor. ", "Meyer is already focusing on the 2018 class because the \"'17 class is pretty much done.\"", "\n\nMeyer loves NFL players coming back. ", "If they handled their business, like Joshua Perry and Joey Bosa, they get lockers at the Woody Hayes Athletic Center and can work out at team facilities. \"", "A guy like Joshua Perry, he probably doesn't have to pay for a meal in Columbus. ", "That's how much he's done for this program.\"" ]
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[ "[Treatment strategy for malignant solid tumors in childhood].", "\nThe prognosis for children with malignant solid tumors has improved dramatically in Japan. ", "During the last two decades, various groups have conducted sequential studies of the treatment of children with neuroblastoma, Wilms' tumor, and hepatoblastoma. ", "Most institutes participated in nonrandomized trials designed to evaluate the safety and efficacy of combination chemotherapy, surgery, and radiotherapy in each group study and treated children with these tumors The results are reviewed and areas for future investigation are identified." ]
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[ "2. ", "Situation en Thaïlande\nLa Présidente\nL'ordre du jour appelle le débat sur six propositions de résolution sur la Thaïlande.", "\nMarietje Schaake\nMadame la Présidente, la Thaïlande connaît actuellement une grave crise avec, d'un côté, les manifestants en \"chemises rouges\" et, de l'autre, l'armée et les \"chemises jaunes\". ", "Près de 80 personnes ont déjà perdu la vie, et quelque 2 000 autres ont été blessées. ", "La démocratie est menacée et le gouvernement a proclamé l'état d'urgence.", "\nL'état d'urgence a entraîné l'instauration d'une censure. ", "Plusieurs médias tels que des chaînes de radio et de télévision, ainsi que des sites Internet, ont été bloqués. ", "Il est certes très important d'arrêter la violence, et nous encourageons l'ensemble des parties à faire preuve de retenue pour y parvenir, mais il ne faut pas que, sous couvert de ramener le calme, l'état d'urgence soit utilisé abusivement pour restreindre les droits fondamentaux et les libertés individuelles. ", "La censure doit cesser, et la liberté d'expression et des médias doit être rétablie. ", "Ces valeurs sont importantes pour le Parlement européen dans ses relations privilégiées avec la Thaïlande.", "\nCristian Dan Preda\nComme nous avons tous pu le constater, car cela fait la \"une\" des actualités, il règne en Thaïlande, depuis le début du mois d'avril, un climat de violence politique comme le pays n'en avait pas connu dans la dernière décennie. ", "Je voudrais tout d'abord exprimer ma profonde solidarité aux familles des victimes des affrontements dans les rues de la capitale. ", "Nous nous trouvons, selon moi, devant un dilemme classique entre, d'une part la liberté d'expression et d'association, et d'autre part la nécessité pour le gouvernement de maintenir l'ordre public. ", "Le rythme des événements s'est fortement accéléré ces derniers jours et ces dernières heures. ", "Un calme relatif semble être revenu à Bangkok, mais la capitale était encore en flammes la nuit dernière, à la suite de l'assaut mené par les forces de l'ordre.", "\nEspérons qu'une nouvelle spirale de violence pourra être évitée. ", "Pour cela, il est indispensable d'user de modération, car la démocratie ne peut pas triompher par la violence. ", "Je pense que le gouvernement devra mettre en œuvre la feuille de route qu'il a présentée le 3 mai. ", "J'estime aussi qu'il sera nécessaire, pour assurer la réconciliation, qu'une enquête soit menée sur les récents événements et que les coupables soient sanctionnés.", "\nVéronique De Keyser\nauteure. - ", "Madame la Présidente, les manifestations des chemises rouges ont été réprimées dans le sang. ", "Sans vouloir jeter de l'huile sur le feu, car une urgence au Parlement européen exige de pacifier une crise et d'y chercher des solutions, plutôt que d'enflammer davantage les passions, je voudrais dire simplement ceci. ", "Premièrement, que tout citoyen peut aspirer légitimement à des élections libres et comme on dit \"fair\". ", "C'est un droit incontestable et ce droit doit être accordé à tous les Thaïlandais. ", "Cette option avait été proposée en son temps par le ministre Vejjajiva, puis repoussée par les chemises rouges. ", "Il faut y revenir.", "\nDeuxièmement, je condamne l'usage de tirs à balles réelles sur les manifestants et la répression brutale de ces derniers jours qui a fait, selon des sources officielles, au moins douze victimes, dont un journaliste italien et de nombreux blessés. ", "Il est temps d'arrêter cette violence qui s'étend à l'ensemble du pays.", "\nCe faisant, je n'épouse pas pour autant l'option d'un camp ou d'un autre, mais j'appelle le gouvernement thaïlandais à privilégier une solution négociée, à s'abstenir de restreindre, par une loi d'urgence, les libertés individuelles et la liberté d'expression, ce qui ne ferait qu'accentuer les tensions, et je l'appelle surtout à envisager un retour aux urnes.", "\nLes troubles actuels risquent de scinder le pays en deux. ", "Il y aurait au nord-est, qui est une zone rurale et de culture laotienne, une opposition quasi insurrectionnelle au centre, à Bangkok et au sud, bastions du parti démocrate avec, à ce moment-là, l'émergence possible de mouvements quasi terroristes, s'attaquant à ce qu'on appellerait la bureaucratie et les élites qui sont les bastions du pouvoir.", "\nNous devons absolument revenir aux élections, à la négociation, à l'arrêt de la violence, mais assurer le maintien des libertés. ", "Ce sont évidemment des mots très simples, et peut-être très naïfs par rapport à la violence d'aujourd'hui, et cette résolution parlementaire est volontairement retenue pour éviter toute déflagration en Thaïlande et laisser sa place au dialogue, mais nous ne pouvons pas pour autant nous dispenser de tout appel à la démocratie.", "\nBarbara Lochbihler\nMadame la Présidente, les images de colère, de violence, et de destruction à Bangkok sont encore fraîches dans nos mémoires. ", "Bien que l'attention des médias soit dans une certaine mesure retombée, la situation reste extrêmement tendue dans la capitale et l'on ne peut absolument pas écarter le risque de nouveaux heurts. ", "Le violent conflit qui a opposé les \"chemises rouges\" au gouvernement, soutenu par l'armée, a déjà fait plus de 70 morts et près de 2 000 blessés. ", "Le gouvernement a annoncé qu'il allait mener une enquête sur ces décès, et il faudra que les décès survenus ces derniers jours soient également compris dans cette enquête.", "\nLa recherche d'une solution politique viable passe par une réflexion sur les causes fondamentales de ces manifestations et de ces crises récurrentes. ", "Une partie de la population thaïlandaise est très défavorisée et se trouve dans une situation d'exclusion sociale. ", "Elle est très critique vis-à-vis de son absence de droits et du traitement injuste qui lui est réservé. ", "Elle se révolte contre la faiblesse de son niveau de vie par rapport au reste du pays. ", "À cela s'ajoute la corruption colossale et systématique qui règne dans la classe politique, mais aussi parmi les dirigeants de la société civile. ", "Ces problèmes structurels doivent être exposés au grand jour et réglés, si l'on veut parvenir à une solution durable, et non pas se contenter de mettre fin aux hostilités.", "\nNous appelons toutes les parties au conflit à engager un dialogue sérieux et constructif pour trouver une solution à cette crise majeure. ", "Elles ne doivent pas chercher à y aboutir autrement que par des moyens pacifiques et démocratiques, et, pour cela, elles ont besoin du soutien de l'Union.", "\nMarie-Christine Vergiat\nauteure. - ", "Madame la Présidente, depuis plusieurs semaines, le mouvement populaire des \"chemises rouges\" manifestait à Bangkok pour exiger le respect de la démocratie. ", "Rappelons que le gouvernement actuel, même si le Président n'est au pouvoir que depuis décembre 2008, résulte néanmoins d'un coup d'État militaire qui remonte à septembre 2006.", "\nQue demandaient les \"chemises rouges\"? ", "La démission du Premier ministre, la dissolution du parlement, des élections anticipées, bref, la démocratie. ", "Le 4 mai, le Premier ministre avait annoncé un plan de réconciliation avec ces fameuses élections anticipées, mais l'assassinat, le 13 mai, du général Khattiya, chef militaire des chemises rouges, a mis fin aux négociations.", "\nC'est dans ce contexte que nous avons préparé la résolution qui est soumise aujourd'hui. ", "Hier, l'armée est intervenue, faisant plusieurs morts, dont un journaliste italien. ", "Pour nous, il est indispensable que les solutions que nous allons voter tiennent compte de ces événements, d'autant plus qu'immédiatement, les principaux leaders des chemises rouges se sont rendus et ont appelé la population au calme.", "\nEn fait, c'est la question de la succession du roi qui est en cause. ", "Celui-ci est étrangement silencieux. ", "Le message que nous devons faire passer est que la démocratie ne s'impose jamais par la force, qu'il n'est pas supportable de réprimer des manifestations en envoyant l'armée avec ordre de tirer à vue. ", "La résolution ne condamne même pas les violences. ", "Nous ne la voterons pas. ", "Les Thaïlandais ont droit à la démocratie et il faut tout faire pour éviter un nouveau coup d'État militaire.", "\nAdam Bielan\nLa Thaïlande - pays considéré jusqu'à récemment comme un bastion de la démocratie et de la stabilité en Asie du Sud-Est - vient de connaître ses heures les plus dramatiques depuis presque un demi-siècle.", "\nLe conflit se poursuit entre les \"chemises rouges\", partisans de l'ancien Premier ministre Thaksin Shinawatra, et le gouvernement et l'armée. ", "Plus de 60 personnes ont été tuées, parmi lesquelles des ressortissants étrangers et, parmi eux, des citoyens d'États membres de l'Union européenne; près de 2 000 personnes ont été blessées, et la capitale, Bangkok, a subi de graves dommages.", "\nLes familles des victimes méritent bien évidemment l'expression de notre sympathie, de notre solidarité et de nos condoléances les plus vives, mais nous devons aussi être conscients que la nation thaïlandaise est aujourd'hui très divisée. ", "Des droits humains, comme la liberté de réunion par exemple, ont été sévèrement restreints, et ce conflit sera très difficile à résoudre par des moyens pacifiques et politiques.", "\nC'est pourquoi la communauté internationale et l'Union européenne en particulier doivent faire pression sur les deux parties en conflit pour qu'elles reprennent les pourparlers et s'efforcent de régler leurs différends par des moyens politiques, et non par la violence.", "\nThomas Mann\nMadame la Présidente, rien que la semaine dernière, dans des combats de rue qui ont tourné à la guerre civile, 75 personnes ont été tuées et plus de 1 800, blessées. ", "Après l'assaut final lancé par l'armée, les chefs des manifestants se sont rendus. ", "La situation à Bangkok continue cependant de s'aggraver. ", "J'ai reçu des appels téléphoniques à ce sujet hier et aujourd'hui même. ", "Jusqu'à présent, certains quartiers de la capitale avaient été épargnés par le conflit, mais ce n'est plus le cas. ", "La situation est également chaotique dans le Nord-Est. ", "Derrière toutes ces images dramatiques, il y a un message clair: quelle que soit la couleur de leur chemise: rouge, noire, jaune ou verte, les gens doivent arrêter la violence et ne pas permettre une nouvelle aggravation de la situation.", "\nLa position du groupe du Parti populaire européen (Démocrates-Chrétiens) est claire. ", "Il n'y a pas d'alternative à des négociations concrètes entre les parties. ", "Une commission d'enquête indépendante doit faire la lumière sur tous ces incidents. ", "Nous sommes très favorables au plan qui prévoit des élections législatives anticipées. ", "L'Union européenne, Monsieur Tajani, l'UE doit jouer un rôle actif et agir en médiateur. ", "Nous avons les moyens diplomatiques de rompre la spirale de violence et d'engager un processus de dialogue constructif. ", "Monsieur Tajani, nous devons agir, car la Thaïlande est aujourd'hui ébranlée dans ses fondements.", "\nCorina Creţu\nJe souhaite moi aussi exprimer ma solidarité aux familles thaïlandaises endeuillées à la suite des violents affrontements dans les rues de Bangkok. ", "La situation est d'autant plus alarmante qu'il n'y a pas de réelle perspective de solution dans ce conflit interne. ", "Les représailles dans les rues de la capitale de la Thaïlande, qui ont fait des dizaines de morts et des centaines de blessés, ne peuvent en aucune manière être acceptées comme moyen de résoudre les problèmes existants.", "\nL'usage brutal de la force et l'instauration d'une censure qui interdit aux chaînes de télévision de diffuser d'autres programmes que ceux approuvés par le gouvernement, constituent des violations des droits humains fondamentaux. ", "Il est du devoir de l'Union européenne et de l'ensemble du monde civilisé de condamner le recours à la force armée contre des civils, et de réclamer la libération de toutes les personnes détenues illégalement ainsi qu'une enquête aussi impartiale que possible sur les décès survenus lors des récents événements. ", "Les pertes en vies humaines ne font que renforcer l'intransigeance de l'opposition et alimenter la violence, qui s'est désormais propagée au nord-est du pays.", "\nCes émeutes risquent de dégénérer en guerre civile. ", "Je crois que les organisations internationales, et au premier chef les Nations unies, doivent intervenir au plus vite pour empêcher une dégradation plus dramatique encore de la situation et favoriser la reprise du nécessaire dialogue entre les autorités et l'opposition, qui représente la seule option démocratique pour résoudre la crise actuelle par des moyens pacifiques.", "\nJoe Higgins\nMadame la Présidente, je condamne la répression brutale que le gouvernement et l'État thaïlandais ont exercée contre les manifestants à Bangkok et dans le reste du pays. ", "Contrairement à ce qu'en a dit la propagande, qui en a fait des terroristes, ces manifestants étaient, pour la plupart, des paysans appauvris du nord du pays et de la plaine autour de Bangkok, ainsi que des sections de la classe ouvrière urbaine, avec leurs familles, qui voyaient dans leur contestation une révolte contre leur immense pauvreté et l'extrême dureté de leur vie.", "\nMalheureusement, c'est vers le milliardaire et ancien Premier ministre Thaksin Shinawatra que ces masses opprimées se sont tournées pour trouver une solution. ", "Malgré certaines mesures populistes qu'il a prises contre la pauvreté lorsqu'il était au gouvernement, M. Thaksin est un représentant de l'élite capitaliste et ne fait qu'abuser les masses. ", "En face, on a l'actuel Premier ministre Abhisit et son parti, qui représentent d'autres sections de l'élite.", "\nJe pense que les masses paysannes pauvres et la classe ouvrière urbaine en Thaïlande ont besoin de toute urgence de former leur propre organisation indépendante pour lutter pour leurs droits, et j'espère que la prochaine mobilisation en Thaïlande sera celle d'un combat unifié des ouvriers, des paysans, des étudiants et de la jeunesse pour renverser les élites corrompues, nationaliser l'essentiel de la richesse du pays en la plaçant sous contrôle démocratique et, dans une Thaïlande socialiste, transformer la vie des citoyens et, aussi, défendre les droits de toutes les minorités.", "\nMonica Luisa Macovei\n(EN) Madame la Présidente, je condamne l'usage de tirs à balles réelles contre les manifestants en Thaïlande: des dizaines de personnes sont mortes, des centaines ont été blessées. ", "Comme l'a déclaré Amnesty International, les récits de témoins oculaires et des enregistrements vidéo montrent clairement que l'armée tire à balles réelles sur des personnes sans armes qui ne représentent aucune menace pour les soldats ni pour personne. ", "Parmi les morts, il y a des médecins et des enfants.", "\nLes soldats thaïlandais doivent cesser de tirer; la violence contre les manifestants ne peut pas conduire et ne conduira pas à une solution démocratique. ", "Le gouvernement doit être conscient que la répression brutale des manifestants les éloigne peut-être provisoirement de la rue, mais ne résoudra pas le problème qui les y a amenés; et la vie humaine passe avant tout, alors arrêtez les tirs.", "\nMiroslav Mikolášik\n(SK) Les manifestations en Thaïlande se poursuivent malheureusement sans relâche depuis plusieurs semaines. ", "La population civile est la première à en souffrir; elle est directement victime des affrontements sanglants entre des manifestants antigouvernementaux armés et les forces de l'ordre. ", "Je voudrais à ce propos exprimer toute ma sympathie à ceux qui ont perdu des proches dans ces événements.", "\nDans cette situation extrêmement tendue, je considère comme une priorité absolue pour les deux parties qu'elles cessent tout recours à la force, afin d'éviter de nouveaux bains de sang. ", "Je soutiens également les appels à mettre un terme immédiat aux violences en cours et à ouvrir un dialogue constructif en vue de régler le conflit par des moyens pacifiques et démocratiques. ", "Parallèlement, j'en appelle au gouvernement thaïlandais pour qu'il n'ait pas recours à des violations arbitraires et injustifiées des droits de l'homme pendant l'état d'urgence.", "\nJaroslav Paška\n(SK) Le conflit politique en Thaïlande s'est très vite transformé en une situation insurrectionnelle qui a eu pour résultats de nombreux décès parmi les manifestants, à la suite de l'intervention des forces armées. ", "Tout gouvernement qui se retourne contre son propre peuple en déchaînant une répression incontrôlée mérite d'être condamné.", "\nIl faut donc, Madame la Présidente, Monsieur le Commissaire, que l'Union européenne use de son influence politique auprès des parties en conflit et appelle à une solution pacifique, afin que le peuple thaïlandais ne fasse pas les frais des différends politiques entre les chefs des différents mouvements en présence. ", "Le gouvernement thaïlandais, en particulier, doit assumer la responsabilité d'apporter une solution sereine et pacifique à ce conflit.", "\nSergio Paolo Francesco Silvestris\n(IT) Madame la Présidente, Monsieur le Commissaire, Mesdames et Messieurs, un cessez-le-feu et la levée de la censure: telle est, à mon sens, la double mesure que la Commission, avec la plus grande détermination, mais aussi la plus grande cohérence avec les valeurs que cette Assemblée considère comme inaliénables, doit s'efforcer d'obtenir.", "\nDans un climat de guerre civile comme celui qui règne aujourd'hui en Thaïlande, un retour à la démocratie par l'organisation d'élections libres - option dont il a été question un moment, et que l'on espérait voir se réaliser, mais qui semble aujourd'hui remise en question - passe nécessairement par une manifestation claire, de la part de la communauté internationale, de son soutien au peuple thaïlandais et au retour du pays à une démocratie pleine et entière.", "\nSi l'on veut que la communauté internationale puisse être associée au processus, l'information est le facteur le plus crucial, et c'est pourquoi l'état d'urgence ne doit pas être une forme de censure déguisée. ", "L'internet, les journaux, et l'ensemble des médias doivent être en mesure de rendre compte à la communauté internationale de la dynamique qui se joue en Thaïlande, afin que la communauté internationale puisse accompagner, en toute connaissance de cause, ce moment de retour à la démocratie.", "\nAntonio Tajani\nvice-président de la Commission. - ", "Madame la Présidente, Mesdames et Messieurs les députés, la Thaïlande traverse une phase tragique de son parcours politique. ", "Le pays, reconnu pour son dynamisme économique et social, est actuellement touché par une crise profonde qui pourrait menacer sa stabilité si une solution n'est pas trouvée au conflit actuel.", "\nEn effet, cette crise atteint le cœur même du pays; une grande partie de la population semble avoir perdu confiance dans les institutions qui la gouvernent. ", "Le gouvernement, à son tour, éprouve des difficultés pour mettre en œuvre les solutions qui s'imposent dans les circonstances actuelles. ", "Il en découle une fragilité politique qui se traduit par des confrontations violentes et par des actes d'agression qui touchent directement aux droits de l'homme et aux droits fondamentaux. ", "L'incertitude plane sur l'évolution future du pays. ", "L'Union européenne déplore, devant cette situation, la perte de vies humaines telles que celle du journaliste italien Fabio Polenghi, qui a été tué hier matin au cours des affrontements entre manifestants et militaires. ", "Aucune crise politique ou idéologique ne peut justifier ce fait, ni la confrontation armée.", "\nÀ deux reprises, la haute représentante a déjà rappelé aux parties en conflit de faire preuve de modération. ", "Même une situation d'état d'urgence ne peut donner lieu à des mesures disproportionnées en termes de droits fondamentaux et d'expression individuelle. ", "Ces droits sont menacés par l'usage disproportionné de la force.", "\nAfin d'éviter toute aggravation de la situation, il est fondamental que les négociations reprennent. ", "La Commission a pris bonne note de la feuille de route présentée par le Premier ministre, Abhisit. ", "La Thaïlande ne pourra émerger de la crise actuelle qu'à la condition de répondre aux problèmes structurels profonds. ", "Il est primordial que les revendications légitimes des couches sociales défavorisées soient reconnues par toutes les parties concernées par la gouvernance du pays. ", "Il s'agit là d'une étape indispensable en vue de la réconciliation nationale. ", "Il est donc impératif pour la Thaïlande de trouver un consensus avec toutes les parties sur la manière d'évoluer vers une société plus incisive.", "\nL'Union européenne, comme partenaire de la Thaïlande, reste disposée à la soutenir dans la mesure de ses capacités en ce processus complexe.", "\nLa Présidente\nLe débat est clos.", "\nLe vote aura lieu prochainement.", "\nDéclarations écrites (article 149)\nBruno Gollnisch \npar écrit. - ", "La Thaïlande traverse un moment très grave de son histoire. ", "Le \"pays du sourire\" est devenu celui des larmes, du sang, peut-être demain celui de la guerre civile entre les forces gouvernementales et ceux que l'on appelle les chemises rouges. ", "Comment a-t-on pu en arriver à un point où une manifestation réclamant l'organisation d'élections démocratiques se solde par des dizaines de mort et des milliers de blessés, l'assassinat politique d'un chef de l'opposition, des scènes de guérilla urbaine, un début d'insurrection dans plusieurs provinces et l'instauration de l'état d'urgence et de couvre-feux? ", "Le Roi, figure si respectée dans le pays, ne semble pas en mesure d'apaiser les tensions. ", "Les incertitudes qui planent sur sa succession laissent présager la poursuite de cette situation d'instabilité. ", "Les violences doivent cesser. ", "Le gouvernement actuel est certes issu d'élections, mais ce sont des élections intervenues à la suite d'un coup d'État et de la dissolution des partis d'opposition! ", "Cette injustice doit cesser. ", "La solution ne peut résider que dans l'organisation rapide d'élections générales, et le rétablissement préalable des libertés politiques de toutes les parties en cause pour en garantir le caractère démocratique. ", "L'Union européenne doit user de ses bonnes relations économiques et politiques avec la Thaïlande pour faire aboutir cette solution.", "\n" ]
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[ "2004 Quintarelli Recioto (375ml)\n\nFor 100 years this small producer from the Veneto has been exporting limited quantities to the U.S. The absolute traditionalist has not changed the techniques set by his father. ", "As those who are familiar with Quintarelli know, he creates miracles in off vintages and legends when Mother Nature shines - and in 1990, 1993 and 1995 she did just that, rivaling her efforts of 1990 and perhaps 1976 or 1985. ", "For Giuseppe, like his father, the challenge of Recioto is a labor of love. ", "After arrested fermentation, which provides Recioto's distinctive sweetness, this wine's vinification follows the same pattern as for the Amarone." ]
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[ "Nicolás Miremont –\n\nAfter Santiago Ascacíbar’s move to VfB Stuttgart last week in what was the club’s biggest ever transfer, the Bundesliga is likely to welcome another Argentinian by the end of the week as the transfer of Lucas Alario from River Plate to Bayer 04 Leverkusen has been unofficially confirmed by his agent yesterday. ", "According to the player’s agent, the move is “already completed”, the contract is signed, and it is only a matter of time until Leverkusen trigger the release clause of €18 million to acquire the services of the lethal front man.", "\n\nDespite the fact that the transfer seemed to be all but concluded there are still many complications. ", "Lucas Alario’s transfer to Bayer Leverkusen is, in fact, turning into a sort of telenovela.", "\n\nThe Transfer Window is the Worst Part of the Year in South America\n\nWith the closing stages of the European transfer window already upon us, the most interesting part of this period loathed by some and patiently awaited by others has finally commenced. ", "A series of weeks in which speculation emerges among football fans, players and managers alike as the teams from all over the world are allowed to modify their squads whether by adding new talent or by getting rid of those who are no longer useful to their particular cause. ", "However, it is only this final part of the transfer window that gathers most of the attention due to the nature of its signings: the most awaited and the less expected.", "\n\nIn South America, this period in-between seasons is hardly ever a pleasant time. ", "All the top clubs on the continent are almost entirely dismantled year after year—since very few can manage to resist the lunge of European capitals and their opportunities.", "\n\nInevitably after the rise of Argentina’s new premium selection of high-quality players and the aforementioned nature of the game on the continent, the transfer window becomes a feast for Europe. ", "Comparable to Latin American tourists on holiday in Miami, most European teams bring their trolleys from across the ocean and enter the mall that is the Argentine league looking for top quality products at amazingly affordable prices.", "\n\nAbout Lucas Alario’s Controversial Transfer\n\nEven though he has already posed wearing a Leverkusen jersey, Alario’s future is still a mystery, for not a single part of the move is official yet because the two clubs have not come to an agreement.", "\n\nOnly days ago, when even some River fans believed the transfer threat was over and they remained confident that the team would not lose any more key pieces like Sebastián Driussi, information of Lucas Alario undergoing a medical that River never authorised made the alarms go off in the northern part of Buenos Aires. ", "Soon after, pictures of the player wearing a Leverkusen’s jersey and holding another one showing his likely future squad number on the reverse of it caused mayhem within the River world, with a powerful demonstration of anger and a terrible sense of loss from the fans. ", "This attitude was considered improper by the club and its supporters, to which Alario’s agent responded: “He is not happy about the way he is leaving, but it was the only way out”. ", "This is when, according to the agent, Alario signed a contract that will make him a Leverkusen player for the next five years.", "\n\nBack in February, Lucas Alario received a rather tempting offer from China, which he turned down without hesitating in the hopes of earning a significant move abroad shortly. ", "Apparently, his decision was the correct one since two top Bundesliga sides have already shown interest in him as Borussia Dortmund had already scouted the player a month before Leverkusen got in contact with him and convinced him of signing for Heiko Herrlich’s side.", "\n\nRiver Plate obviously are not satisfied with the way things were handled and is now threatening to take the case to FIFA’s authorities questioning an alleged violation of a principle in the association’s transfer regulations (article 16) which states that a contract cannot be unilaterally rescinded should the affected club be already competing officially. ", "With the team weeks away of facing the CONMEBOL Libertadores quarter-finals and the Argentine Superliga already underway, River is trying to avoid the loss of their hitman. ", "They are therefore recurring to legal action and therefore accusing Bayer 04 Leverkusen of also violating the article 17 of the transfer regulation, arguing the German team might have induced Alario to break his contract in the middle of an official competition.", "\n\nWill Alario Make it in Time to the Bundesliga?", "\n\nWhile the player’s side remains confident that the deal will happen, River Plate’s position seems quite rigid. ", "In fact, they have refused to provide their bank account information to Bayer 04 Leverkusen in what is another episode of the wonderfully bizarre world of South American football.", "\n\nThe German club have already done everything in their power to make the transfer happen and as it seems they have also played their cards very well. ", "However, they could not have done it on their own since the player’s agent has played a significant role in this scandal. ", "According to the press, he was the one who advised Leverkusen to buy Colón de Santa Fe´s share of Alario’s transfer (40%), something that will certainly put some pressure on River’s side.", "\n\nThe most interesting part of this quarrel is that the transfer window closes on September 31, in less than 24 hours. ", "Will Leverkusen manage to register Alario in time? ", "Apparently, they will, for they already have a signed contract at their disposal. ", "However, will they be allowed to deposit the payment? ", "That remains uncertain as of yet and currently constitutes Leverkusen’s primary concern and the player is already trying to get the operation done through AFA instead of River with a formal complaint. ", "Nevertheless, even if the transfer happens, legal sanctions could be on the way for the German club.", "\n\nBoth parts have already stated their opinions on the matter and are waiting for responses from the authorities:\n\nRiver Plate’s lawyer spoke to the press and made clear that “[River] still has not received any formal information concerning the payment which one way or another we are not going to accept since the clause exceeds the boundaries of the regulation and FIFA will act on behalf of the disadvantaged club”.", "\n\nThe player’s agent, on the other hand, are confident that “Colón’s story, River’s complaints and everything that is being said do not concern us, it is the clubs who have to sort this situation out. [", "Leverkusen] is paying €18 million and Alario is going to Germany”.", "\n\nIt certainly looks like we are in for a proper thriller approaching the end of the transfer window. ", "Lucas Alario will inevitably move to Bayer Leverkusen (stay tuned for his scouting report on fussballstadt.com). ", "In the meantime, enjoy the last chapters of this great telenovela.", "\n\nNicolás Miremont is a born and raised Boca Juniors fan, but his heart has a special place for Manchester United, Zenit Saint Petersburg and Dynamo Kiev. ", "Miremont loves to support the underdogs. ", "Miremont enjoys watching smaller competitions especially those from Eastern Europe, but also his native Argentina. ", "Follow him on Twitter @Miremont_Nico" ]
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[ "Differences in efficacy between intention-to-treat and per-protocol analyses for patients with psoriasis vulgaris and atopic dermatitis: clinical and pharmacoeconomic implications.", "\nPharmacoeconomic outcome research is based on three criteria: (i) evaluation of objective therapeutic effects; (ii) quality of life; and (iii) treatment costs. ", "Evaluation of therapeutic effect is mainly based on the results of clinical trials using objective clinical measures, e.g: Psoriasis Area and Severity Index (PASI) (score for psoriasis vulgaris) and the Severity Scoring of Atopic Dermatitis (SCORAD) (score for atopic dermatitis). ", "In most studies, only results for a treatment-optimized subpopulation (patients treated according to the protocol) are presented in publications. ", "The relevance of such data for daily routine therapy is doubtful. ", "Our purpose was to investigate the expected loss of effectiveness of switching from a clinical trial to daily routine therapy for the synchronous application of narrow-band ultraviolet (UV) B phototherapy (311 nm) and bathing in 10% Dead Sea salt solution (synchronous balneophototherapy) for patients with psoriasis vulgaris and atopic dermatitis. ", "We conducted a multicentre, uncontrolled observational study of outpatients. ", "To achieve data for 'clinical trial' and 'daily routine' situations, two populations were compared: (i) all patients strictly treated according to the protocol (ATP) with no protocol deviations (data published in clinical trials), and (ii) all patients participating in the study who received active treatment at least once, despite treatment irregularities, non-compliance, early withdrawal or other protocol violations [intention-to-treat-population (ITT), model for 'daily routine']. ", "A total of 2526 patients were included in the ITT analysis for psoriasis vulgaris (n = 487 for atopic dermatitis), of which 818 patients could be analysed according to protocol (n = 104 for atopic dermatitis). ", "Striking differences in the therapeutic effect between both groups (ITT and ATP) were found using relative PASI and SCORAD score improvement: 11% (57% 'daily routine' vs. 68% in 'clinical trial') for psoriasis vulgaris and 16% (39% 'daily routine' vs. 55% 'clinical trial') for atopic dermatitis. ", "The main reasons for excluding patients from the 'clinical trial' group were early study withdrawal in 29% (atopic dermatitis, 47%) of patients and fewer treatments per week than planned in the protocol in 24% (atopic dermatitis, 52%). ", "Our data clearly indicate that for the prediction of the therapeutic effect for daily routine therapy the ITT data appear to be more relevant than the ATP results (i.e. those presented in clinical trials). ", "Although these data are only a first step for evaluating the 'real' therapeutic effect of a treatment modality in daily routine, they seem to support the requirements for ITT analyses in efficacy studies and demonstrate the necessity of ITT data for pharmacoeconomic evaluation." ]
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[ "Q:\n\ncant reach asp.net page on other server\n\nI have defined an asp.net mvc app on server x. I added the sitename in the hostfile:\n127.0.0.1 weeral.com\n\nAlso in IIS 7 i have added this as a sitebinding hostname weeral.com\nWhen I hit http://weeral.com it responds find on the server.", "\nHowever when I ping weeral.com from a different machine in the network it goes:\nPing request could not find host weeral.com. ", "Please check the name...\n\nwhat am i doing wrong?", "\n\nA:\n\nThe different machine doesn't have the same host file.", "\nYou need to map 127.0.0.1 to weeral.com on every one of the machines you use. ", "If you used Dropbox (or something similar) you could symbolically link the machine's host file to the one in your Dropbox. ", "I've done this for other config files, so I would think it would work for the host file.", "\n\n" ]
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[ "Flu deaths more than double in SC compared to last season\n\nCOLUMBIA, S.C. (AP) — South Carolina health officials say 15 people have died of the flu so far this season, more than double the number of deaths at this time last year.", "\n\nThe S.C. Department of Health and Environmental Control reports the 15 deaths occurred through Jan. 6. ", "That's compared to seven deaths through the same period in 2017 and six deaths through the same period in 2016.", "\n\nHealth officials tell The State newspaper in Columbia that the first week of January also marked the fourth week in a row that widespread flu activity has been reported. ", "And it's spreading fast.", "\n\nDHEC's latest week-to-week report states that the number of cases went up by 1,395, or 40.6 percent, when compared to the previous week. ", "There have been 17,004 cases statewide since the season started." ]
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[ "[Coronary Artery Perforation during Excimer Laser Coronary Angioplasty;Report of a Case].", "\nCoronary perforation during excimer laser coronary angioplasty( ELCA) is a rare but life threatening complication. ", "A 55-year-old man was admitted to our hospital for management of acute coronary syndrome. ", "ELCA was attempted for the left anterior descending coronary artery (LAD);however, coronary perforation of LAD occurred during the procedure. ", "The patient was transferred to the operation theater and emergency surgical repair was performed. ", "LAD and the diagonal branch were ligated, an aorto-coronary bypass grafting for the distal LAD and the diagonal branch using the saphenous veins. ", "His postoperative course was uneventful, and the patient was discharged on the 23rd postoperative day. ", "In case of coronary perforation complicated by ELCA, immediate surgical repair is essential." ]
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[ "HLSS\n\nHLSS can refer to:\n\n Half-Life Sound Selector, a program that allows users to play audio files using voice communication on games developed by Valve.", "\n Heart Lake Secondary School, a high school in Brampton, Ontario, Canada\n Hopscotch Lollipop Sunday Surprise, a 2001 album by The Frogs\nSchool of Humanities, Languages and Social Sciences (UWE), Bristol" ]
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[ "Friday, January 31, 2014\n\nFeathery fiascos: the unfortunate prey for peace\n\nPhotographers in St. Peter’s Square last Sundat caught the sad scene of\na freshly released dove being attacked by a crow and seagull.", "\n\nThe annual dove launch by the pope and two children is meant to highlight the church’s call for peace in the world.", "\n\nBut, unfortunately, the forces of nature (namely hungry predator\nbirds circling the square) usually prevail every year and the symbol of\npeace becomes prey.", "\n\nI did a story several years ago that looked at the problem and an\neasy solution that would not appall bird lovers and would keep the\nchildren’s month of peace tradition flying.", "\n\nPerhaps the advice and the story originally published Feb. 13, 2004, are worth repeating?", "\n\nWing and a prayer: Vatican doves sometimes turn chicken\n\nBy Carol Glatz\n\nVATICAN CITY (CNS) — The noble white dove has come to symbolize\npeace, fidelity, fraternity and hope, but the Vatican seems to have seen\nmore than its fair share of doves suffering from a fear of flying.", "\n\nSome might even say those doves are really just chicken.", "\n\nWhat’s meant to be an impressive launch from the fifth-story window\nof the pope’s studio instead turns into a feathery fiasco. ", "In 1998 both\ndoves recoiled from their release and turned tail back inside the\napostolic palace.", "\n\nDelighted, Pope John Paul II said, “It is clear this\nis a house of peace, because the doves don’t want to leave.”", "\n\nThis scene of one or both doves diving for papal cover has been\nrepeated over the years.", "\n\nMost recently, on Jan. 25, call it\nstage-fright, call it premonition: One dove refused to leave the pope’s\nwindowsill while the more gutsy of the two flew off to a grisly fate.", "\nOne Italian newspaper reported the bird of peace was later found injured\nfrom a seagull attack.", "\n\nThe dove-launch over St. Peter’s Square occurs the last Sunday of every January after the pope’s Angelus.", "\n\nThe annual avian event started 25 years ago, said Father Antonio\nMagnotta, assistant to the Rome branch of Italy’s Catholic Action youth\ngroup. ", "He said the group asked the Vatican if the kids could help\ncelebrate what’s considered the month of peace with their bishop, Pope\nJohn Paul.", "\n\nEach year, two children join the pope at the end of his noonday prayer, read a message of peace and help launch two white doves.", "\n\nIf only symbolism could be so simple.", "\n\n“The problem is they toss the doves out with too much force; the bird\ndoesn’t know where it’s going, so it boomerangs back to get its proper\nbearings,” said Bernard de Cottignies, veteran Vatican Radio journalist\nand messenger-dove fancier with several champion birds under his cote.", "\n\n“To get a good takeoff they should slowly open their hands, let the\nbird get its sense of direction, and then it will go when it’s ready,”\nhe said.", "\n\nLaunching techniques aside, how much is known about where the doves go at the end of the show?", "\n\n“They head to the Vatican gardens, I think,” Father Magnotta said.", "\n\nBut officials at the Vatican’s immaculately pruned gardens told CNS that there are no white doves there.", "\n\n“We have lots of grey pigeons, but white doves? ", "I never saw them here,” said the head of the gardens, Elio Cortellessa.", "\n\nDe Cottignies said the white doves end up homeless and starving.", "\n\n“White doves are usually bred for meat and lack the homing instinct\nof messenger-doves” — which are also known as “racing pigeons,” he said.", "\n\nAnother problem with farm-raised fowl, he said, is that the white dove cannot fend for itself in the city.", "\n\nBut luckily for the doves, there was a Good Samaritan looking out for them for a while.", "\n\n“For five years I picked up the stray doves, half-starved and lost in\nSt. Peter’s Square on my way home from work to take them to a friend’s\nhouse in the country,” confessed de Cottignies.", "\n\nAlthough the release of doves onto St. Peter’s Square is wholly\norganized by Italian Catholic Action, once upon a time the Vatican used\ndoves in its beatification and canonization ceremonies.", "\n\nAccording to a Franciscan Web site, the Mass’s offertory after the\nact of canonization was made up of “wax candles, bread, wine, water, two\nturtle doves, two pigeons and a number of smaller birds” in gilded\ncages.", "\n\nThese offerings were presented to the pope and were meant to “lift up\nour hearts and minds to the love and contemplation of the\nsupernatural,” the Web site explained.", "\n\n“I remember in 1976 when the Scottish Jesuit martyr (John Ogilvie)\nwas canonized, the Jesuits turned up with wine and a dove,” said Msgr.", "\nCharles Burns, a church historian who spent more than 25 years as an\nofficial of the Vatican Archives.", "\n\nBut Archbishop Piero Marini, the pope’s master of liturgical\nceremonies, said that after the Second Vatican Council, the use of doves\nand other symbols in liturgical ceremonies was phased out in favor of\nsimpler gifts.", "\n\n“But the present-day tradition of the children coming to the pope’s\nwindow to release the doves is very nice,” Msgr. ", "Burns said. “", "It’s a lot\nlike Noah’s Ark,” the dove flying back from land, symbolizing hope and\npeace.", "\n\nDe Cottignies said there is a solution that would not appall bird\nlovers and would keep the children’s month of peace tradition flying.", "\n\n“They could use white messenger-doves. ", "They would have a much more\nstunning takeoff since the bird knows where home is and would head\nstraight there with impressive speed,” he said." ]
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[ "Last month, Yonder Mountain String Band hosted the Northwest String Summit at Horning’s Hideout in North Plains, Oregon. ", "A standout performance of the 15th annual event was the YMSB set on Saturday, July 16 that saw the band’s complete re-creation of the Pink Floyd album Animals. ", "Pro-shot video footage of “Pigs” covered as part of the tribute set has been posted by Yonder and EPIC Creative.", "\n\nYonder Mountain String Band was joined for the duration of the Animals set by drummer Jay Elliott and keyboardist Asher Fulero. ", "Sung by Adam Aijala, who donned an electric guitar for the performance, the cover expanded to the 14 minute mark. ", "Watch “Pigs (Three Different Ones)” here:\n\nAnd here’s additional previously shared footage of the 25+ minute “Dogs” and fiddle player Allie Kral handling lead vocals on the “Wish You Were Here” encore, also produced by EPIC Creative:\n\nSetlist (via PT Yonder)\n\nSet One: Winds Of Wyoming> Around You> Winds Of Wyoming, Love Before You Can’t, Bound to Ride, Casualty> Sidewalk Stars> Casualty, Remind Me1, Criminal1\n\nSet Two: Pigs On The Wing1> Dogs1> Pigs (Three Different Ones)1> Sheep1> Pigs On The Wing1\n\nEncore: Fearless1, Wish You Were Here1\n\n1 – Jay Elliott on drums and Asher Fulero on keys & vocals" ]
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[ "Q:\n\nAlternativas ao beforeunload event listener no FF\n\nEstou a trabalhar num website e JavaScript tem um papel importante no front-end, estava a usar o evento beforeunload para fazer sempre uma verificação se o utilizador editou algo na página, para avisa-lo sobre possíveis perdas de informação. ", "\nAcontece que este evento não é compatível com o firefox. ", "Que alternativa posso usar para fazer essa verificação? ", " \n\nA:\n\nO onbeforeunload deve funcionar.", "\nExemplo de código - compatível com IE >= 7 também\nvar myEvent = window.attachEvent || window.addEventListener;\nvar chkevent = window.attachEvent ? '", "onbeforeunload' : 'beforeunload';\n\nmyEvent(chkevent, function(e) {\n fazerAlgumaCoisa();\n});\n\nSolução testada no Firefox Nightly 53.0a1\n\n" ]
{ "pile_set_name": "StackExchange" }
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0.005217
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[ "About this item\n\nDescription\n\nAt 24 inches deep and 60 inches wide, shelf space is abundant. ", "Shelf height can easily be moved up or down in one inch increments giving you just the right height between shelves. ", "Four caster wheels allow for easy maneuverability and placement in your room. ", "NSF listed means it's safe in any food environment.", "\n\nSpecifications\n\nChrome plated steel finish\n\n5 height adjustable shelves\nleveling feet\n\n4 inch caster wheels (two locking)\n\n600 lb. ", "per shelf capacity using leveling feet\n\nNSF listed for food safety\n\nAssembled Country\n\nChina\n\nAssembled Size\n\n60\"W x 24\"D x 72\"H\n\nComponent Country\n\nImported\n\nMember reviews & questions\n\nAsk & Answer\n\nPolicies & plans\n\nShipping Information\n\nStandard - 2 to 6 business days\n\nPremium - 2 to 4 business days\n\nExpress - 1 to 2 business days\n\nWarranty Information\n\nThis product is covered by the Sam's Club Member Satisfaction Guarantee.", "\n\nStay Connected\n\nMobile apps\n\nSign up for email updates!", "\n\nWe'll send you updates on price savings events, special offers, new items, in-club events, and more. ", "At this time, registration for email is unavailable in Puerto Rico. ", "For more information, see our privacy policy." ]
{ "pile_set_name": "Pile-CC" }
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[ "Combination cancer immunotherapy and new immunomodulatory targets.", "\nTargeting immune checkpoints such as programmed cell death protein 1 (PD1), programmed cell death 1 ligand 1 (PDL1) and cytotoxic T lymphocyte antigen 4 (CTLA4) has achieved noteworthy benefit in multiple cancers by blocking immunoinhibitory signals and enabling patients to produce an effective antitumour response. ", "Inhibitors of CTLA4, PD1 or PDL1 administered as single agents have resulted in durable tumour regression in some patients, and combinations of PD1 and CTLA4 inhibitors may enhance antitumour benefit. ", "Numerous additional immunomodulatory pathways as well as inhibitory factors expressed or secreted by myeloid and stromal cells in the tumour microenvironment are potential targets for synergizing with immune checkpoint blockade. ", "Given the breadth of potential targets in the immune system, critical questions to address include which combinations should move forward in development and which patients will benefit from these treatments. ", "This Review discusses the leading drug targets that are expressed on tumour cells and in the tumour microenvironment that allow enhancement of the antitumour immune response." ]
{ "pile_set_name": "PubMed Abstracts" }
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[ "Kerala Chief Minister, Shri Pinarayi Vijayan today announced that the Regional Cancer Centre (RCC) at Thiruvananthapuram has started a cancer treatment centre at the Kanyakumari District Hospital for the benefit of cancer patients in Kanyakumari and surrounding districts who usually depend on RCC, Thiruvananthapuram for their treatment.", "\n\nGiving details, the Chief Minister said there are currently 560 patients from that area undergoing treatment at RCC, Thiruvananthapuram but they are not able to reach here during the lockdown period. ", "To address this issue, RCC, Thiruvananthapuram in association with the Tamil Nadu Health Department and with the support of Tamil Nadu Government has started this cancer treatment centre at Kanyakumari.", "\n\nIt may be recalled that the Kerala Government had set up 22 Cancer treatment centres across all the 14 districts in the State in association with the Regional Cancer Centre (RCC) at Thiruvananthapuram. ", "This would enable cancer patients to continue their follow-up treatment including chemotherapy at their nearest Cancer treatment centre during this Covid period.", "\n\nMinister of Health & Social Justice, Smt K K Shailaja; Revenue Minister, Shri E Chandrasekharan, and Chief Secretary, Shri Tom Jose IAS were also present during the media briefing." ]
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[ "Buster Skrine\n\nDarryl Frank \"Buster\" Skrine Jr. (pronounced \"screen\") (born April 26, 1989) is an American football cornerback for the Chicago Bears of the National Football League (NFL). ", "He was drafted by the Cleveland Browns in the fifth round of the 2011 NFL Draft. ", "He played college football for the University of Tennessee at Chattanooga.", "\n\nEarly years\nSkrine attended Etowah High School in Woodstock, Georgia, where he starred in both offense and defense. ", "As a junior, he was named All-County at defensive back as a junior and was selected team's Most Valuable Player of the year after recording 61 tackles and two interceptions. ", "He was a five-time County Player of the Week, and helped lead the Eagles to an 8-4 record and the second-round of the state playoffs, where Etowah won its first Region 5A title in school history. ", "As a senior, he led Cherokee County in rushing yards with 1,071 on 167 rushes and 15 touchdowns. ", "He caught 17 balls for 363 yards and a score as a receiver, and also tallied 89 tackles from the secondary with 66 solo stops, had one interception and a fumble recovery. ", "For his senior season, he earned All-county, All-region and All-state honors, and was named as the Cherokee County Player of the Year.", "\n\nSkrine was also a top competitor in track & field. ", "He won the 2007 County Championship in the triple jump (43-3 or 13.25m) and finished second in the long jump (22-7 or 6.92m), leading this to earn All-County honors in track.", "\n\nCollege career\nSkrine attended the University of Tennessee at Chattanooga, where he was twice named to the First Team All-Southern Conference.", "\n\nProfessional career\n\nCleveland Browns\nThe Cleveland Browns selected Skrine in the fifth round (137th overall) of the 2011 NFL Draft. ", "Skrine was the 20th cornerback drafted in 2011.", "\n\n2011\nOn July 30, 2011, the Cleveland Browns signed Skrine to a four-year, $2.24 million contract that includes $202,000 guaranteed.", "\n\nThroughout training camp, Skrine competed for a job as a backup cornerback against Ramzee Robinson, Coye Francies, and Dimitri Patterson. ", "Head coach Pat Shurmur named Skrine the fourth cornerback on the Browns' depth chart to begin the regular season, behind Joe Haden, Sheldon Brown, and Dimitri Patterson.", "\n\nHe made his professional regular season debut in the Cleveland Browns' season-opener against the Cincinnati Bengals and made two solo tackles in their 27–17 loss. ", "Skrine made his first career tackle on kick returner Brandon Tate during a 35-yard kick return in the second quarter by Tate. ", "On November 5, 2011, Skrine was elevated to nickelback after Dimitri Patterson sprained his knee the previous week. ", "On December 18, 2011, Skrine recorded two solo tackles, a pass deflection, and made his first career interception during a 20–17 overtime loss at the Arizona Cardinals in Week 15. ", "He intercepted a pass attempt by quarterback John Skelton that was originally intended for Early Doucet and returned it for five-yards in the fourth quarter. ", "He completed his rookie season in with 18 combined tackles (14 solo), two pass deflections, and an interception in 16 games and zero starts. ", "Defensive coordinator Dick Jauron primarily used Skrine in nickel and dime packages. ", "He was also used on special teams.", "\n\n2012\nDuring training camp, Skrine competed against Dimitri Patterson for the job as the third cornerback. ", "Head coach Pat Shurmur named Skrine the fourth cornerback on the depth chart to begin the season, behind Joe Haden, Sheldon Brown, and Dimitri Patterson. ", "Skrine was elevated to the third cornerback on the depth chart after starting cornerback Joe Haden was suspended for the first four games after violating the league's substance abuse policy.", "\n\nOn September 16, 2012, Skrine earned his first career start after Sheldon Brown was demoted to nickelback. ", "He recorded seven solo tackles during a 34–27 loss at the Cincinnati Bengals in Week 2. ", "In Week 6, Skrine recorded nine combined tackles and a season-high three pass deflections in the Browns' 41–27 loss to the New York Giants. ", "The following week, he collected a season-high 11 combined tackles (eight solo) during a 34–24 loss to the Cincinnati Bengals in Week 7. ", "He finished his second season in with 85 combined tackles (72 solo), 11 pass deflections, and a fumble recovery in 16 games and six starts. ", "On December 31, 2012, the Cleveland Browns fired head coach Pat Shurmur and general manager Tom Heckert, Jr. after the Browns finished with a 5–11 record.", "\n\n2013\nThroughout training camp, Skrine competed for the job as the starting cornerback against Chris Owens and Leon McFadden. ", "Head coach Rob Chudzinski named Skrine a starting cornerback to open the regular season, alongside Joe Haden.", "\n\nOn September 15, 2013, Skrine made his first start of the season and collected a season-high nine combined tackles and broke up a pass in the Browns' 14–6 loss at the Baltimore Ravens in Week 2. ", "In Week 4, he made two combined tackles, a season-high three pass deflections, and intercepted a pass by Andy Dalton during a 17–6 win against the Cincinnati Bengals. ", "The following week, he made six solo tackles, two pass deflections, and made his first career sack in a 37–24 victory against the Buffalo Bills in Week 5. ", "He sacked quarterback E. J. Manuel for a one-yard loss in the third quarter. ", "He finished the season with 65 combined tackles (55 solo) a career-high 18 passes defensed, and a sack in 16 games and 15 starts. ", "On December 30, 2013, the Cleveland Browns fired head coach Rob Chudzinski after a season where the Browns finished with a 4-12 record. ", "Skrine earned an overall grade of -12.1 from Pro Football Focus in 2013.", "\n\n2014\nSkrine entered training camp slated as a backup after the Cleveland Browns drafted Justin Gilbert in the first round of the 2014 NFL Draft. ", "Head coach Mike Pettine opted to instead name Skrine the starting cornerback to begin the regular season, along with Joe Haden.", "\n\nIn Week 6, Skrine made three solo tackles, a season-high four pass deflections, and intercepted a pass by Ben Roethlisberger during a 31–10 victory against the Pittsburgh Steelers. ", "The following week, he intercepted his second pass of the season during a 24–6 loss at the Jacksonville Jaguars in Week 7. ", "On November 2, 2014, Skrine collected a season-high nine combined tackles in the Browns' 22–17 victory against the Tampa Bay Buccaneers in Week 9. ", "In Week 10, he made three combined tackles, three pass deflections, and intercepted two passes by quarterback Andy Dalton during a 24–3 victory at the Cincinnati Bengals. ", "He completed the 2014 season with 67 combined tackles (55 solo), a career-high 18 pass deflections, and a career-high four interceptions in 16 games and 16 starts. ", "He earned an overall grade of -6.3 from Pro Football Focus in 2014.", "\n\n2015\nSkrine became an unrestricted free agent in 2015 and garnered interest as a developing starting caliber cornerback. ", "He decided to enter free agency and test the market instead of re-signing with the Cleveland Browns. ", "It was reported that 15 teams inquired about signing Skrine, including the New York Giants, but were unable to meet Skrine's salary demands.", "\n\nNew York Jets\nOn March 10, 2015, the New York Jets signed Skrine to a four-year, $25 million contract that includes $13 million guaranteed and a signing bonus of $5 million.", "\n\nHe entered training camp slated as the third cornerback on the depth chart and the Jets' first-team nickelback. ", "Head coach Todd Bowles officially named him the third cornerback on the depth chart to start the regular season, behind Darrelle Revis and Antonio Cromartie. ", "In Week 14, Skrine collected a season-high eight combined tackles, broke up a pass, and made an interception during a 30–8 victory against the Tennessee Titans. ", "He finished the season with 56 combined tackles (46 solo), seven pass deflections, and an interception in 16 games and eight starts.", "\n\n2016\nSkrine became a starting cornerback to begin the regular season in 2016 after the Jets chose not to re-sign Antonio Cromartie. ", "On October 2, 2016, Skrine collected four combined tackles and sacked quarterback Russell Wilson during a 27–17 loss to the Seattle Seahawks in Week 4. ", "On October 23, 2016, Skrine recorded a season-high six combined tackles, deflected a pass, and returned an interception by Joe Flacco for a 51-yard gain in the Jets' 24–16 win against the Baltimore Ravens in Week 7. ", "Skrine injured his knee and was inactive for the Jets' Week 8 victory at the Cleveland Browns. ", "His injury ended his 87-game streak and was the first time he missed a game during his career. ", "He went on to also miss the Jets' Week 15 loss to the Miami Dolphins after he sustained a concussion the previous week. ", "He finished the season with 47 combined tackles (39 solo), six passes defensed, an interception, and a sack in 14 games and 14 starts. ", "Pro Football Focus gave Skrine an overall grade of 45.5, which ranked 89th among all qualifying cornerbacks in 2016.", "\n\n2017\nDefensive coordinator Kacy Rodgers retained Skrine as the starting cornerback to begin the regular season, alongside Morris Claiborne, after the Jets released Darrelle Revis. ", "In Week 3, Skrine collected a season-high eight solo tackles and sacked quarterback Jay Cutler in the Jets' 20–6 win against the Miami Dolphins. ", "On October 15, 2017, Skrine made two solo tackles, a season-high three pass deflections, and intercepted a pass by Tom Brady in a 24–17 loss to the New England Patriots. ", "He was inactive for the Jets' Week 8 loss to the Atlanta Falcons after sustaining a concussion. ", "He finished the season with 63 combined tackles (56 solo), nine passes defensed, an interception, and a sack in 15 games and 15 starts. ", "Pro Football Focus gave Skrine an overall grade 65.7, which ranked 85th among all qualifying cornerbacks in 2017.", "\n\n2018\nSkrine finished the 2018 season with 58 tackles, 8 passes defended, and half a sack in 14 games and 11 starts. ", "He received an overall grade of 57.3 from Pro Football Focus in 2018, which ranked as the 103rd highest grade among all qualifying corner backs.", "\n\nChicago Bears\n\n2019\nOn March 13, 2019, Skrine signed a three-year, $16.6 million contract with the Chicago Bears.", "\n\nPersonal life\nSkrine was given the nickname \"Buster\" from his grandmother because his father also shares the same first name. ", "Skrine began teaching high-intensity interval training classes during the 2017 offseason out of the Kore studio located in New York City's Meatpacking District.", "\n\nReferences\n\nExternal links\n \n New York Jets bio\n\nCategory:1989 births\nCategory:American football cornerbacks\nCategory:Chattanooga Mocs football players\nCategory:Chicago Bears players\nCategory:Cleveland Browns players\nCategory:Living people\nCategory:New York Jets players\nCategory:People from Decatur, Georgia\nCategory:Players of American football from Georgia (U.S. state)\nCategory:Sportspeople from DeKalb County, Georgia" ]
{ "pile_set_name": "Wikipedia (en)" }
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[ "Q:\n\nImprove Performance On GUI log\n\nThanks to Yair Altman's excellent post on undocumentedmatlab.com, I've tried to implement a GUI logging program using a rich editbox and the underlying java components. ", "Here is the simplified version of the code:\nFirst the code to create the panel\nfunction jEditbox = logPanel()\n hFig = figure('color', 'w');\n hPanel = uipanel(hFig);\n\n % Prepare the log editbox\n hLogPanel = uicontrol('style', 'edit', 'max', 5, 'Parent', hPanel, ...\n 'Units', 'normalized', 'Position', [0, 0.2, 1, 0.8], 'Background', 'w');\n\n % Get the underlying Java editbox, which is contained within a scroll-panel\n jScrollPanel = findjobj(hLogPanel);\n try\n jScrollPanel.setVerticalScrollBarPolicy(jScrollPanel.java.", "VERTICAL_SCROLLBAR_AS_NEEDED);\n jScrollPanel = jScrollPanel.getViewport();\n catch %#ok<CTCH>\n % may possibly already be the viewport, depending on release/platform etc.", "\n end\n jEditbox = handle(jScrollPanel.getView, 'CallbackProperties');\n\n % Prevent user editing in the log-panel\n jEditbox.setEditable(false);\n\n % Set-up a Matlab callback function to handle hyperlink clicks\n set(jEditbox,'HyperlinkUpdateCallback',@linkCallbackFcn);\n\n % Ensure we have an HTML-ready editbox\n HTMLclassname = 'javax.swing.text.html.", "HTMLEditorKit';\n if ~isa(jEditbox.getEditorKit, HTMLclassname)\n jEditbox.setContentType('text/html');\n end\nend\n\nThen the logging code:\nfunction logMessage(jEditbox, text)\n % newText = [iconTxt, msgTxt ' '];\n text = [text '<br/>'];\n\n % Place the HTML message segment at the bottom of the editbox\n currentHTML = char(jEditbox.getText);\n newHTML = strrep(currentHTML, '</body>', text);\n jEditbox.setText(newHTML);\n endPosition = jEditbox.getDocument.getLength;\n jEditbox.setCaretPosition(endPosition);\nend\n\nI have two problems:\n\nThere are major performance issues in applications that will require a large number of logged messages (i.e. > 500). ", "Using the profiler and the following code (note that I've modified why to return a string rather than printing to the command line), I've seen that the bottleneck is with setText(). ", "Can anyone explain what the spikes in the graph are?", "\nh = logPanel();\n\nn = 1e3;\ntime = nan(n, 1);\nprofile on\nfor i = 1:n\n tic\n logMessage(h, why)\n time(i) = toc;\nend\nprofile viewer\navgTime = mean(time);\nfigure('color', 'w')\nbar(time)\nhold on\nplot([0, n], avgTime*ones(1, 2), '-k', 'LineWidth', 2)\nhold off\ntitle(sprintf('Average Time = %f [s]', avgTime));\n\nIf I add a pause(0.1) after the toc, then the graph looks like\n\nWhat's going on here?", "\nThis results in a very \"flashy\" log panel. ", "Each time I write a message, the contents flicker as it scrolls to the top and then back to the bottom. ", "Once again, this defect is due to setText(), which forces the caret to the beginning of the document.", "\n\nI'm looking for solutions to either of these problems, preferrably both.", "\n\nA:\n\nOf course, using getText(), String manipulation and setText() is a bottleneck. ", "You force the editor component to convert it’s entire contents into an HTML representation and to reparse the entire HTML representation after the change. ", "The editor is not able to detect that you just added a bit of text. ", "The more contents your component has, the higher the performance loss.", "\nIf you have a Swing text component and want to append some text at the end you can use:\n\n(the easy one) for plain text:\ntextComp.setCaretPosition(textComp.getDocument().getLength());\ntextComp.replaceSelection(\"\\nMore Text\");\n\n(not so much harder) for text in the content type, e.g. HTML:\nDocument doc = textComp.getDocument();\ntextComp.getEditorKit().read(\n new StringReader(\"More <i>styled</i> text\"), doc, doc.getLength());\n\nIn the second case, if you want to move the caret to the end you have to add the setCaretPosition invocation like in the first case.", "\n\n" ]
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[ "LaTeX for Linux: A Vade Mecum\n\nKurzbeschreibung\n\nThis comprehensive guide to using LaTeX is directed at Linux and UNIX users but is also the best how-to book on the use to LaTeX to prepare articles, books and theses. Unlike other LaTeX books it is especially useful for someone coming to LaTeX for the first time." ]
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[ "06/28/14 Chart Added\n\nTechnical Analysis: The quick post signal change signal (L) was posted on the last hour of Friday trading. ", "The model portfolio is now long. ", "In the trading action following the June 19 pop, the gold market held up well and featured limited selling (so no real give back). ", "The risk reward ratio is now favorable again.", "\n\nWhat is next? ", "The trading trend is still up and we have support a nearby levels. ", "It is time to prepare for the mummy to start moving up. ", "The Iraqi civil war news is going to be supportive though to what degree, we will have to see. ", "This week will be truncated (July 4th, no trading), potentially limiting selling appetite again. ", "-GHG" ]
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[ "Nicholls is not bringing enough athletes to win a conference championship, however, most of the athletes competing for the Colonels rank at or near the top of their respective events meaning some individuals could win championships or earn medals.", "\n\nColonels coach Heather Van Norman said a team title is out of the question, but she does expect her athletes to score points and be competitive.", "\n\n\"I think what we do have is quality. ", "We have quality student-athletes, and they have brought out the best in themselves. ", "We have athletes that have a lot of talent and that can score a number of points,\" Van Norman said. \"", "We don't have the depth to compete for a team title, but our girls have worked hard on and off the field. ", "I'm looking forward to building this squad and bringing in more people that can score points and compete in this conference.\"", "\n\nNicholls has three athletes ranked No. ", "1 in their events entering the conference meet.", "\n\nJackie White and Tessni Carruthers rank first and second in both the 800-and 1500-meter runs. ", "White tops the list of runners in the 800-meter with a time of 2 minutes, 10.64 seconds, while Carruthers has the top 1500-meter time at 4:29.92. ", "The other runner that tops an event list is Kryshell Rolle who has the best time in the 100-meter hurdles at 13.90. ", "Rolle also ranks third with a time of 1:01.37 in the 400-meter hurdles.", "\n\nWhite said after a successful indoor and outdoor season, she is confident she can improve on her times and win a medal.", "\n\n\"My confidence is way up, and that is not to say I can't be beaten, but having success has given me confidence. ", "Placing at the conference meet is important, but all during the season I just wanted to drop my times,\" White said. \"", "I want to reach that next level, and I really want to get to regionals, but everyone in the conference is looking good. ", "I want to get to regionals in the 800, but I've been at the same time. ", "I hope to have that race where I can drop two or three seconds off my time. ", "I really need that perfect race and not get boxed in, and I think it can happen at conference.\"", "\n\nWhite, Carruthers and Rolle are all on the cusp of earning berths to the NCAA East Regional Track and Field Championship in Greensboro, N.C. on May 23-25.", "\n\nTo get invited to the regional meet, athletes have to finish in the Top 48 in their region and two Colonels have already qualified for the regional meet in the javelin event.", "\n\nJaimee Springer and Aja Scott both are expected to do well at the conference championships and will be attending the East regional meet also.", "\n\nSpringer has had a successful outdoor season winning five meets and placing second in two other meets. ", "Even though she has won five meets, Springer enters the conference meet ranked third in the javelin.", "\n\nSpringer said she has steadily improved throughout the season and the competition she has faced has prepared her for the conference meet.", "\n\n\"The competition is stiff just like every year. ", "The girls in the Southland can't be taken for granted. ", "These girls can throw as far as girls from bigger conferences. ", "You can't go there and expect to walk in and win. ", "Anything can happen and a lot of girls are throwing in that 145 to 150 range,\" Springer said. \"", "I came into this year wanting to hit my final mark of last season in the first meet and improve from there. ", "I showed up big when it counted against good competition, and I made those 150-plus throws. ", "I'm trying to hit 155, and if I can hit 160 that would be a plus. ", "Of course you go in and you want to win and get that gold medal and represent Nicholls.\"", "\n\nSpringer ranks 25th overall in the East region entering the conference meet, while Scott is seventh in the conference in the javelin and No. ", "44 overall in the East region.", "\n\nVan Norman said if her athletes reach their potential, the conference meet will be a success and Springer and Scott may have company in two weeks at the regional meet.", "\n\n\"Everyone has had a personal best, so it is a matter of everyone coming together this weekend and scoring as many points as we can,\" Van Norman said. \"", "We have several people knocking on that door to get into the regional. ", "All they have to do is drop a few seconds off their time. ", "We are putting in extra training so we are going to go for it and see what happens. ", "All I ask is for them to do what they are capable of doing. ", "We are not going out to do something fancy or set world records. ", "Just do what you are capable of, and if we can get a slight improvement, things could fall into place for several athletes.\"", "\n\n<p>If success breeds success, then Nicholls State University's women's track and field team should expect a successful weekend at the 2013 Southland Conference Track and Field Championships.</p><p>The conference championship meet begins today at McNeese State's Cameron Communications Complex in Lake Charles and ends on Sunday.</p><p>Nicholls is not bringing enough athletes to win a conference championship, however, most of the athletes competing for the Colonels rank at or near the top of their respective events meaning some individuals could win championships or earn medals.</p><p>Colonels coach Heather Van Norman said a team title is out of the question, but she does expect her athletes to score points and be competitive.</p><p>\"I think what we do have is quality. ", "We have quality student-athletes, and they have brought out the best in themselves. ", "We have athletes that have a lot of talent and that can score a number of points,\" Van Norman said. \"", "We don't have the depth to compete for a team title, but our girls have worked hard on and off the field. ", "I'm looking forward to building this squad and bringing in more people that can score points and compete in this conference.", "\"</p><p>Nicholls has three athletes ranked No. ", "1 in their events entering the conference meet.</p><p>Jackie White and Tessni Carruthers rank first and second in both the 800-and 1500-meter runs. ", "White tops the list of runners in the 800-meter with a time of 2 minutes, 10.64 seconds, while Carruthers has the top 1500-meter time at 4:29.92. ", "The other runner that tops an event list is Kryshell Rolle who has the best time in the 100-meter hurdles at 13.90. ", "Rolle also ranks third with a time of 1:01.37 in the 400-meter hurdles.</p><p>White said after a successful indoor and outdoor season, she is confident she can improve on her times and win a medal.</p><p>\"My confidence is way up, and that is not to say I can't be beaten, but having success has given me confidence. ", "Placing at the conference meet is important, but all during the season I just wanted to drop my times,\" White said. \"", "I want to reach that next level, and I really want to get to regionals, but everyone in the conference is looking good. ", "I want to get to regionals in the 800, but I've been at the same time. ", "I hope to have that race where I can drop two or three seconds off my time. ", "I really need that perfect race and not get boxed in, and I think it can happen at conference.", "\"</p><p>White, Carruthers and Rolle are all on the cusp of earning berths to the NCAA East Regional Track and Field Championship in Greensboro, N.C. on May 23-25.</p><p>To get invited to the regional meet, athletes have to finish in the Top 48 in their region and two Colonels have already qualified for the regional meet in the javelin event.</p><p>Jaimee Springer and Aja Scott both are expected to do well at the conference championships and will be attending the East regional meet also.</p><p>Springer has had a successful outdoor season winning five meets and placing second in two other meets. ", "Even though she has won five meets, Springer enters the conference meet ranked third in the javelin.</p><p>Springer's distance of 152-feet 1-inch, is behind Stephen F. Austin's Madison Johnston's distance of 161-feet and Northwestern State's Jessica Tally's mark of 157-9.</p><p>Springer said she has steadily improved throughout the season and the competition she has faced has prepared her for the conference meet.</p><p>\"The competition is stiff just like every year. ", "The girls in the Southland can't be taken for granted. ", "These girls can throw as far as girls from bigger conferences. ", "You can't go there and expect to walk in and win. ", "Anything can happen and a lot of girls are throwing in that 145 to 150 range,\" Springer said. \"", "I came into this year wanting to hit my final mark of last season in the first meet and improve from there. ", "I showed up big when it counted against good competition, and I made those 150-plus throws. ", "I'm trying to hit 155, and if I can hit 160 that would be a plus. ", "Of course you go in and you want to win and get that gold medal and represent Nicholls.", "\"</p><p>Springer ranks 25th overall in the East region entering the conference meet, while Scott is seventh in the conference in the javelin and No. ", "44 overall in the East region.</p><p>Van Norman said if her athletes reach their potential, the conference meet will be a success and Springer and Scott may have company in two weeks at the regional meet.</p><p>\"Everyone has had a personal best, so it is a matter of everyone coming together this weekend and scoring as many points as we can,\" Van Norman said. \"", "We have several people knocking on that door to get into the regional. ", "All they have to do is drop a few seconds off their time. ", "We are putting in extra training so we are going to go for it and see what happens. ", "All I ask is for them to do what they are capable of doing. ", "We are not going out to do something fancy or set world records. ", "Just do what you are capable of, and if we can get a slight improvement, things could fall into place for several athletes.", "\"</p>" ]
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0.002995
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[ "We use cookies on this site to provide you with an informative and engaging experience and also to help us to continually improve our site for you.", "\nWithout allowing cookies certain features of the site will not be available. ", "To learn more about how we use cookies, please view our\ncookie policy. ", "By clicking on ‘APPROVE’, you consent to our use of cookies on this device\nin accordance with our policy.", "\n\nFor middle-aged patients with presbyopia, wearing OK contact lenses overnight can restore up-close vision in one eye, according to the study by Paul Gifford, PhD, FAAO, and Helen A Swarbrick, PhD, FAAO, of University of New South Wales, Sydney. \"", "The authors have shown the feasibility of correcting one eye for near vision through OK, in which overnight contact lens wear shapes the cornea of one eye to allow in-focus near vision for reading,\" comments Anthony Adams, OD, PhD, Editor-in-Chief of Optometry and Vision Science.", "\n\nOvernight OK Lens Wear Restores Near Vision in One EyeThe study included 16 middle-aged patients (43 to 59 years) with age-related loss of near vision, or presbyopia. ", "Presbyopia is caused by age-related loss of flexibility in the cornea—the transparent front part that lets light into the eye.", "\n\nOrthokeratology is a clinical technique to correct vision using specially designed rigid contact lenses to manipulate the shape of the cornea. ", "Dr. Adams likens OK therapy to orthodontic treatment using braces to change the alignment of the teeth.", "\n\nDrs. ", "Gifford and Swarbick evaluated a \"monocular\" technique, with patients wearing a custom-made OK lens in one eye overnight for one week. ", "To preserve normal distance vision, the other eye was left untreated.", "\n\nIn all patients, the monocular OK technique was successful in restoring near vision in the treated eye. ", "The improvement was apparent on the first day after overnight OK lens wear, and increased further during the treatment week. ", "Eye examination confirmed that the OK lenses altered the shape of the cornea, as they were designed to do.", "\n\nNightly Lens Wear Needed to Retain CorrectionVision in the untreated eye was unaffected, and all patients retained normal distance vision with that eye; essentially this gives the patient the dequivalent of ‘monovision’ that is usually done with contact lenses or surgery. ", "To retain the correction in near vision, patients had to continue wearing their OK lenses every night. ", "Dr. Adams likens this ongoing treatment to the \"retainer\" that orthodontic patients have to wear nightly. ", "As expected, when patients stopped wearing their OK lens after the treatment week, presbyopia rapidly returned.", "\n\nBy about age 45 to 50, most people need bifocals or some other form of vision correction to restore vision for reading and other up-close tasks. ", "Alternatives for presbyopia have been introduced, including fitting a contact lens for distance vision in one eye and a lens for near vision in the other eye. ", "This is the so called monovision, now the authors show it can be achieved without the need to wear a contact lens during the day. \"", "However, the chief problem with monovision for many people is that their stereoscopic 3D vision is degraded and many find that hard to tolerate,\" according to Dr. Adams.", "\n\nAlthough overnight OK is not a new technique, it has been mainly used to reduce nearsightedness (myopia) in younger patients. ", "The new study shows that OK is similarly effective in changing corneal shape, and achieving desired correction in near vision, in older patients with presbyopia.", "\n\nThe new study suggests that overnight OK lenses are a feasible alternative for correction of presbyopia, \"sufficient to provide functional near vision correction white retaining good distance visual acuity,\" Drs. ", "Gifford and Swarbick write. ", "The technique is safe, with the cornea returning to its previous shape about a week after the patient stops wearing the lenses.", "\n\n\"This study demonstrates that OK is quite viable as a nonsurgical option for monovision that does not require wearing contact lenses during the day, although it does require 'retainer' orthokeratology contact lenses to be worn overnight,\" Dr. Adams adds. \"", "This possibility will certainly appeal to many people, especially since the changes in the corneal curvature of the treated eye are fully reversible.\"", "\n\nAbout Optometry and Vision ScienceOptometry and Vision Science, official journal of the American Academy of Optometry, is the most authoritative source for current developments in optometry, physiological optics, and vision science. ", "This frequently cited monthly scientific journal has served primary eye care practitioners for more than 75 years, promoting vital interdisciplinary exchange among optometrists and vision scientists worldwide.", "\n\nAbout the American Academy of OptometryFounded in 1922, the American Academy of Optometry is committed to promoting the art and science of vision care through lifelong learning. ", "All members of the Academy are dedicated to the highest standards of optometric practice through clinical care, education or research.", "\n\nAbout Lippincott Williams & WilkinsLippincott Williams & Wilkins (LWW) is a leading international publisher of trusted content delivered in innovative ways to practitioners, professionals and students to learn new skills, stay current on their practice, and make important decisions to improve patient care and clinical outcomes.", "\n\nLWW is part of Wolters Kluwer Health, a leading global provider of information, business intelligence and point-of-care solutions for the healthcare industry. ", "Wolters Kluwer Health is part of Wolters Kluwer, a market-leading global information services company with 2012 annual revenues of €3.6 billion ($4.6 billion)." ]
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0.002948
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[ "Cost-effectiveness Analysis of Stereotactic Radiosurgery Alone Versus Stereotactic Radiosurgery with Upfront Whole Brain Radiation Therapy for Brain Metastases.", "\nStereotactic radiosurgery (SRS) alone or upfront whole brain radiation therapy (WBRT) plus SRS are the most commonly used treatment options for one to three brain oligometastases. ", "The most recent randomised clinical trial result comparing SRS alone with upfront WBRT plus SRS (NCCTG N0574) has favoured SRS alone for neurocognitive function, whereas treatment options remain controversial in terms of cognitive decline and local control. ", "The aim of this study was to conduct a cost-effectiveness analysis of these two competing treatments. ", "A Markov model was constructed for patients treated with SRS alone or SRS plus upfront WBRT based on largely randomised clinical trials. ", "Costs were based on 2016 Medicare reimbursement. ", "Strategies were compared using the incremental cost-effectiveness ratio (ICER) and effectiveness was measured in quality-adjusted life years (QALYs). ", "One-way and probabilistic sensitivity analyses were carried out. ", "Strategies were evaluated from the healthcare payer's perspective with a willingness-to-pay threshold of $100 000 per QALY gained. ", "In the base case analysis, the median survival was 9 months for both arms. ", "SRS alone resulted in an ICER of $9917 per QALY gained. ", "In one-way sensitivity analyses, results were most sensitive to variation in cognitive decline rates for both groups and median survival rates, but the SRS alone remained cost-effective for most parameter ranges. ", "Based on the current available evidence, SRS alone was found to be cost-effective for patients with one to three brain metastases compared with upfront WBRT plus SRS." ]
{ "pile_set_name": "PubMed Abstracts" }
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[ "Rolandas Valiūnas\n\nRolandas Valiūnas (born 13 January 1965 in Kybartai, Vilkaviškis District Municipality) is a Lithuanian business lawyer and consultant, Attorney at law, Co-Founder and Managing Partner of \"Ellex Valiūnas ir partneriai\". ", "He is an Honorary Consul of Thailand (since 2004).", "\n\nBiography \n\nFrom 1971 to 1982 Rolandas Valiūnas learned at the 5th Middle school Marijampolė, where he graduated with the gold medal (with distinction). ", "After the Soviet army service he studied law in the graduate studies from 1984 to 1989 at the Law Faculty of Vilnius University. ", "Then he continued his education in 1994 at the Queen Mary & Westfield Coledge, in 1996 at the Academy of International Law in Dallas, Texas. ", "From 1999 to 2000 he studied at the Baltic Management Institute (BMI), the Executive Master of Business Administration (EMBA) program (2000). ", "After that, he was a lecturer in the course of the BMI Institute \"Corporate Governance\".", "\n\nSince 1990 Valiūnas is a lawyer. ", "From 1989 to 1991 he worked in the first law firm in Vilnius, from 1991 to 1992 at the law firm \"Foresta\", in 1992 at the law firm \"Lideika, Petrauskas, Valiūnas ir partneriai\" (LPVP) as managing partner. ", "\n\nAccording to \"The International Who's Who of Business Lawyers\", Rolandas Valiūnas is one of the best Lithuanian lawyers in the area of Corporate Governance, Mergers and acquisitions. ", "He contributed to the national and international conferences regarding business law topics and has authored and was co-author of numerous legal publications in the business press (Verslo žinios etc.).", "\n\nRolandas Valiūnas is CEO of BMI and Investors' Forum in Lithuania, Vice President of ICC Lietuva.", "\n\nFamily and personal life \nRolandas Valiūnas is married to a gynecologist Renata Valiūnienė. ", "\n\nRolandas Valiūnas has the sons Mantas Gabrielius Valiūnas and Giedrius Valiūnas (* 1989).", "\n\nRolandas Valiūnas has daughters Grytė Marija and Elzė Gintvilė.", "\n\nMembership\n2010 – to date Advisory Board, Law Firm Management Committee, International Bar Association (IBA)\n2007 – to date Advisory Board, European Regional Forum, IBA\n2006 to date – Board Member, Vilnius Court of Commercial Arbitration\n2004 - 2006 Co-Chair, European Regional Forum, IBA\n2002 - 2005 Deputy Chairman, Council of Lithuanian Bar Association\n2000 - 2005 Member of General Professional Program Committee, IBA\n1998 to date - Board Member, Legal clinic of Vilnius University\n1995 to date - Recommended arbitrator of Vilnius Court of Commercial Arbitration\n1994 - 1997 President, Lithuanian Young Bar Association (LJAA)\n1991 - 2000 - Vice-President, Union Internationale des Avocats (UIA)\n\nSources \n\nCategory:Living people\nCategory:1965 births\nCategory:People from Kybartai\nCategory:Vilnius University alumni\nCategory:Lithuanian art collectors\nCategory:21st-century art collectors\nCategory:Lawyers from Vilnius\nCategory:Lithuanian consultants\nCategory:Businesspeople from Vilnius\nCategory:Honorary consuls to Lithuania\nCategory:21st-century diplomats\nCategory:Honorary consuls of Thailand\nCategory:20th-century Lithuanian lawyers\nCategory:21st-century Lithuanian lawyers" ]
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[ "Q:\n\nJUnit NullPointerException\n\nI am getting a NullPointerException when trying to test a method in a class with a special type. ", "I am our of ideas as to the reason for this exception.", "\npublic class TestStack {\n private Stack st;\n private Entry en;\n /**\n * @throws java.lang.", "Exception\n */\n @Before\n public void setUp() throws Exception {\n st = new Stack();\n en = new Entry(1);\n }\n\n @Test\n public void pushThenTop() {\n st.push(en);\n assertEquals(\"TEST1: push then Top\", 1, st.top());\n fail(\"Incorrect type\");\n }\n\n}\n\nStack Class\npublic class Stack {\n private int size;\n private List<Entry> entries;\n public void push(Entry i) {\n entries.add(i);\n }\n\n public final Entry pop() throws EmptyStackException {\n if (entries.size() == 0) {\n throw new EmptyStackException();\n }\n Entry i = entries.get(entries.size() - 1);\n entries.remove(entries.size() - 1);\n return i;\n }\n\n public Entry top() throws EmptyStackException {\n return entries.get(entries.size() -1);\n }\n\n public int size() {\n size = entries.size();\n return size;\n }\n}\n\nI am trying to run a test that returns the value of the element in the list.", "\n\nA:\n\nYour Stack class needs to initialize entries to an empty list:\nprivate List<Entry> entries = new ArrayList<>();\n\n" ]
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[ "Q:\n\nReal-time graphs\n\nDo you know of a graphing library similar to Google's Annotated Timeline(\nhttp://code.google.com/apis/visualization/documentation/gallery/annotatedtimeline.html) that can be updated in realtime with new data points? ", " Either javascript or flash is ok.", "\nThanks!", "\n\nA:\n\nA lot of the bigger charting libraries/toolkits will let you update the datasets in 'realtime', if by realtime you mean that you're able to call a function on the chart to introduce new points.", "\nCheck out:\n\nFlot - JQuery\nDojo charting (tutorial)\nFlex Charting (blog post) - Flash\n\n" ]
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[ "Live\n\nWelcome to the October archive of Essential Politics, our daily feed on California politics and government news.", "\n\nFor the latest feed, go here.", "\n\nBe sure to follow us on Twitter for more, or subscribe to our free daily newsletter and the California Politics Podcast" ]
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[ "Inhibition by an extract of Ocimum sanctum of DNA-binding activity of 7,12-dimethylbenz[a]anthracene in rat hepatocytes in vitro.", "\nOcimum sanctum is a traditional medicinal plant. ", "Previous studies have shown that extracts of O. sanctum inhibit the induction of skin papillomas in mice by 7,12-dimethylbenz[a]anthracene (DMBA). ", "In the present study, primary cultures of rat hepatocytes were treated with 0-500 microg of O. sanctum extract for 24 h and then with DMBA (10 or 50 microg) for 18 h. Cells were then harvested and their DNA was isolated and analyzed by 32P-postlabelling. ", "A significant reduction in the levels of DMBA-DNA adducts was observed in all cultures pretreated with O. sanctum extract. ", "This effect was more pronounced at the lower dose of DMBA (10 microg). ", "Hepatocytes which were treated with the highest dose of extract (500 microg) showed a maximum reduction of 93% in the mean values of DMBA-DNA adducts. ", "The viability of the cells was not adversely affected by pretreatment with extract. ", "Our findings suggest that O. sanctum leaf extract blocks or suppresses the events associated with chemical carcinogenesis by inhibiting metabolic activation of the carcinogen." ]
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[ "Pages\n\nTuesday, January 10, 2012\n\nFDA is advising healthcare professionals and patients of a potential problem with opiate products manufactured and packaged for Endo Pharmaceuticals by Novartis Consumer Health at its Lincoln, Nebraska manufacturing site. ", "Due to problems that occurred when these products were packaged and labeled at the site, tablets from one product type may have carried over into packaging of another product. ", "This could result in a stray pill of one medicine ending up in the bottle of another product.", "\n\nThe following products are included:\n\nOpana ER (oxymorphone hydrochloride) Extended-Release Tablets CII\n\nOpana (oxymorphone hydrochloride) CII\n\nOxymorphone hydrochloride Tablets CII\n\nPERCOCET (oxycodone hydrochloride and acetaminophen USP) Tablets CII\n\nPERCODAN (oxycodone hydrochloride and aspirin, USP) Tablets CII\n\nENDOCET (oxycodone hydrochloride and acetaminophen USP) Tablets CII\n\nENDODAN (oxycodone hydrochloride and aspirin, USP) Tablets CII\n\nMORPHINE SULFATE Extended-Release Tablets CII\n\nZYDONE (hydrocodone bitartrate/acetaminophen tablets, USP) CIII\n\nPlease be sure to check the contents of your prescriptions carefully. ", "All of the pills in the bottle should look the same. ", "If the pills don't look like what you normally take or if you find any pills that are different in shape, size, color, or markings, take them to your pharmacist right away.", "\n\nEndo Pharmaceuticals has provided a visual guide of the affected drugs that you can download if you would like to double check the tablets in your prescription: Endo Pharmaceuticals Opioid Guide.", "\n\nDisclaimer: Nothing on this blog is intended as medical or legal advice.", "\n\nWhat I write on this site is my own, and if it is someone else's, I take special care to attribute it to the original author. ", "So, please don't use any of my material without proper attribution or permission. ", "Thanks." ]
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[ "Q:\n\nTranslating \"21st Century Skills\"\n\nThe term \"21st Century Skills\" is used to denote skills like critical thinking, creativity, leadership, media literacy, etc.", "\nHow could this term be translated into Korean?", "\nThe word skill can be translated \"기술\", but 21세기 기술 sounds more like 21st Century Technology, which is quite different, so I'm not sure how to express the idea well in Korean.", "\n\nA:\n\nNavering for \"21st century skills\" brings out the following blog post: \nhttps://blog.naver.com/ednakim/221063703484 \nFrom there: \n\n...skills는 21 세기를 살아가는데 필요한 핵심 역량들을 말합니다. ", " \n\nSome more digging around gets us to this Naver News article: \n\n한국교육개발원, '21세기 핵심역량' 출간 \n【서울=뉴시스】한재갑 교육·학술 전문기자 = 한국교육개발원(KEDI, 원장 김태완)이 「21세기 핵심역량-이 시대가 요구하는 핵심스킬(‘21st Century Skills - Learning for life in our times’의 한국어 번역본)」을 출간했다고 27일 밝혔다.", "\n\nSo I think an appropriate translation can be \n21세기 역량 \n\nbut it seems that online contents refer to it as \n21세기 핵심역량 \n\nso that might actually be a better or a more commonly used term.", "\n\n" ]
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[ "package com.github.dockerjava.api.model;\n\nimport com.fasterxml.jackson.annotation.", "JsonProperty;\nimport lombok.", "EqualsAndHashCode;\nimport lombok.", "ToString;\n\nimport java.io.", "Serializable;\n\n@EqualsAndHashCode\n@ToString\npublic class BlkioWeightDevice implements Serializable {\n public static final long serialVersionUID = 1L;\n\n @JsonProperty(\"Path\")\n private String path;\n\n @JsonProperty(\"Weight\")\n private Integer weight;\n\n public String getPath() {\n return path;\n }\n\n public BlkioWeightDevice withPath(String path) {\n this.path = path;\n return this;\n }\n\n public Integer getWeight() {\n return weight;\n }\n\n public BlkioWeightDevice withWeight(Integer weight) {\n this.weight = weight;\n return this;\n }\n}\n" ]
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[ "Analysis of serum proteins by LC-MS/MS.", "\nSerum contains a vast array of proteins, some of which are specific to blood whilst others are secreted into blood from tissues and organs. ", "The so-called tissue leakage factors reveal information about the tissue from which they originate and are therefore of great potential importance as disease biomarkers. ", "There are already a number of blood-borne biomarkers in routine clinical use that aid in the diagnosis or management of cancer. ", "However, there is a pressing need for additional markers, and new methods to find them are under development. ", "Here we provide a protocol for serum protein profiling using liquid chromatography tandem mass spectrometry (LC-MS/MS). ", "Included in this procedure, we detail the pre-processing steps of lipid and high-abundance protein removal. ", "These procedures can also be employed up-stream of quantification methods such as isobaric tags for relative and absolute quantification (iTRAQ). ", "Chapter 12 is devoted to the iTRAQ approach for quantifying proteins, and it is therefore not described in this chapter." ]
{ "pile_set_name": "PubMed Abstracts" }
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[ "Antigen-capture enzyme immunoassay: a comparison with other methods for the detection of spotted fever group rickettsiae in ticks.", "\nTo evaluate the prevalence of spotted fever group rickettsiae along the Adriatic Coast of Croatia, 832 ticks were examined by hemolymph test, direct immunofluorescence, antigen-capture enzyme immunoassay, and polymerase chain reaction. ", "Very good agreement was observed among direct immunofluorescence, polymerase chain reaction, and antigen-capture enzyme immunoassay. ", "Twelve ticks that were positive by hemolymph test and negative by both direct immunofluorescence and polymerase chain reaction presumably do not represent spotted fever group rickettsiae. ", "By direct immunofluorescence, spotted fever group rickettsiae were present in 12% of Rhipicephalus bursa, 10.6% of Rh. ", "sanguineus, and 7.8% of Dermacentor marginatus. ", "From the 98 ticks containing rickettsia-like organisms by hemolymph test, seven spotted fever group rickettsial isolates were established in cell culture. ", "Four isolates were identified as Rickettsia conorii. ", "The antigen-capture enzyme immunoassay, which utilizes a monoclonal antibody to antigens of the 135-kD surface protein shared among many members of the spotted fever group, is recommended for primary screening of tick samples because it is reliable and yet less labor-intensive than the hemolymph and direct immunofluorescence tests. ", "Although the polymerase chain reaction is too expensive for use as a screening method, it is recommended for confirmation of positive screening results. ", "In addition to the technologic advance of the antigen-capture enzyme immunoassay, this study documented by contemporary methods that R. conorii is present along the eastern Adriatic Coast not only in the classic vector, Rh. ", "sanguineus, but also in Rh. ", "bursa and D. marginatus." ]
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[ "Introduction {#s1}\n============\n\nTraumatic brain injury (TBI) is the result of an acute insult to the head due to a variety of external causes, such as a motor vehicle accident, firearm, or fall. ", "Interestingly, initial trauma to the head is often followed by secondary brain tissue damage, which is recognized as a major risk factor for Alzheimer\\'s Disease (AD) [@pone.0078851-OMeara1]--[@pone.0078851-Plassman1]. ", "The Centers for Disease Control and Prevention estimates that over 5.3 million Americans live with disabilities as a result of TBI [@pone.0078851-Sarmiento1], [@pone.0078851-Thomas1]. ", "Despite the staggering number, the consequential biological processes accompanying TBI are poorly understood. ", "It is critical that we develop strategies to limit the secondary brain damage that follows initial head trauma and to devise effective therapies to improve long-term recovery of function. ", "AD is a neurodegenerative disorder characterized pathologically by progressive neuronal loss and both intraneuronal and extracellular aggregates of beta-amyloid (Aβ) peptides. ", "Although a pathological link between TBI and AD has not been well-defined, a tau pathology referred to as chronic traumatic encephalopathy (also called dementia pugilistica) has been described in the brains of individuals exposed to repetitive, often mild or concussive, head injury such as boxers [@pone.0078851-Roberts1], [@pone.0078851-Dale1] and football players [@pone.0078851-Omalu1]--[@pone.0078851-McKee2]. ", "This study is designed to clarify the pathological link between TBI and AD. ", "We hypothesized that TBI precipitates early presence of AD, with pathological disturbance manifested in discreet brain regions (such as the cortex and the hippocampus), along with accompanying cognitive impairment [@pone.0078851-Kline1], [@pone.0078851-Matsuda1]. ", "While the cortex is directly impacted in TBI, secondary cell death ensues in the hippocampus, a critical brain structure for memory and learning. ", "Indeed, many patients later suffer from TBI-related dementia, implicating the role of the hippocampus in the disease progression [@pone.0078851-DeKosky1], [@pone.0078851-Miller1]. ", "Because the adult hippocampus is a well-established neurogenic site highly sensitive to both acute and chronic injury [@pone.0078851-Forbes1]--[@pone.0078851-Feng1], this specific brain region appears to be an optimal candidate to study secondary pathological disturbance after an initial cortical injury. ", "Interestingly, accelerated Aβ aggregation has been recently detected in transgenic AD mice at 24 hours and seven days after TBI [@pone.0078851-Tran1]. ", "Moreover, the systemic treatment of a compound designed to inhibit γ-secretase activity, a proteolytic process required for Aβ production, suppressed the TBI-induced Aβ accumulation in these injured mice at both time points [@pone.0078851-Tran1]. ", "Extending this acute TBI-induced AD histopathology to a more long-term period, and demonstrating its behavioral correlate (specifically an expedited cognitive decline), should further advance the TBI and AD pathological link.", "\n\nHere, we examined the possible exacerbating cognitive and histopathological impact of TBI on AD in presymtomatic APP/PS-1 AD-transgenic mice and non-transgenic (NT) mice using the controlled cortical impact (CCI) model. ", "The present study began at age three months and ended at age five months. ", "This study should provide a better understanding of the long-term role of trauma in AD pathology, thereby advancing novel treatments aimed at arresting cellular injury and removing Aβ deposition from the brain to retard the symptoms of AD and TBI.", "\n\nMaterials and Methods {#s2}\n=====================\n\nEthics Statement {#s2a}\n----------------\n\nAll experiments were conducted in accordance with the recommendations in the Guide for the Care and Use of Laboratory Animals of the National Institutes of Health. ", "The protocol was approved by the Institutional Animal Care and Use Committee at the University of South Florida. ", "All efforts were made to minimize animal suffering. ", "Mice were housed individually, in a temperature- and humidity-controlled room that was maintained on 12/12 hour-light/dark cycles. ", "They had free access to food and water.", "\n\nSubjects {#s2b}\n--------\n\nThe subjects were obtained through pre-determined breeder pairs, combining mutant Tg2576 APP mice with mutant PS1 line 5.1 transgenic mice, which generated NT, APP, APP+PS1, and PS1 transgenic offspring with a mixed background of (C57B6/SJL/SwissWebster/B6D2F1). ", "Upon weaning, subjects were genotyped by Southern blot analysis. ", "Three-month old AD transgenic mice were used in this study. ", "This age represents the AD pre-symptomatic stage in this particular transgenic mouse, wherein mice are cognitively normal although they have already begun to produce and accumulate Aβ in their brains. ", "To clarify the effects of TBI on these mice, cognitive and neurohistological effects were evaluated for two different cohorts of animals. ", "The first cohort included four treatment groups: AD mice + TBI (AD-TBI; n = 7), AD mice + sham surgery (AD-Sham; n = 8), NT mice + TBI (NT-TBI; n = 10), and NT mice + sham surgery (NT-Sham; n = 9). ", "The second cohort included the same four treatment groups: AD-TBI (n = 8), AD-Sham (n = 8), NT-TBI (n = 7), and NT-Sham (n = 7). ", "Animals in cohort 2 were exposed to the same surgical procedure, but were not subjected to any behavioral testing before and after the surgery.", "\n\nPre-surgery Procedures {#s2c}\n----------------------\n\nTo assess cognitive changes following TBI, all mice in cohort 1 were subjected to 14 days of pre-TBI training in the radial arm water maze (RAWM) task. ", "The apparatus was a black circular pool (100 cm diameter), in which an aluminum insert was placed to form a RAWM. ", "In the apparatus, six swim arms (32 cm length and 19 cm width) radiated from the central circular swim region (36 cm diameter). ", "A clear round platform (9 cm diameter) was placed near the end of one of the arms at 1.5 cm beneath the surface of the water. ", "Surrounding the pool, a visual cue was placed at each end of the radial arms, including an inflatable flamingo, a bouquet of silk flowers, a bean bag pumpkin, a plush flower, and a beach ball. ", "These visual cues were placed at random heights and proximity to the pool and aligned with the center of each arm. ", "Additional extramaze cues (e.g. light fixtures, cabinets, etc.) ", "were also present, with the experimenter remaining stationary at the same location to also serve as one of the visual cues. ", "Each daily session consisted of four acquisition trials (T1--T4), followed by a 30-minute delay interval and then a retention trial (T5). ", "For each session, the escape platform was placed at the end of one of the goal arms, with a different semi-randomized goal arm selected for each daily session. ", "At the beginning of each trial, the subject was placed at the end of one of the remaining five non-goal arms. ", "The mouse was positioned facing the wall, away from the center. ", "Each trial lasted 60 seconds, during which an animal was allowed to swim in order to find the platform. ", "The number of entries to the non-goal arms were recorded as errors. ", "The error occurred when the subject\\'s full body length entered into an incorrect arm, including the goal arm if the platform was not found. ", "The subject was allowed to swim to the end of the incorrect arm, then gently guided back to the starting location after every error. ", "Once the subject found the platform, a 30-second resting period on the platform was permitted before beginning the next trial for T1-T4. ", "If the subject failed to find the platform within 60 seconds, it was guided to the platform and allowed a 30-second resting period. ", "After the completion of T4, the mouse was removed from the pool, dried with a towel, and returned to its cage for 30 minutes. ", "The procedures for T5 were identical to T1-T4, with the start arm being the one remaining non-goal arm not used in the four prior trials for that day. ", "Only one five-trial session per day was performed. ", "Pre-TBI testing sessions continued for a total of 14 days until all mice performed at an average of two or fewer errors across T4 and T5. ", "The experimenter remained unaware of the animals\\' genotypes throughout all of the behavioral testing. ", "After training, there were no performance differences between AD mice (n = 19) and NT mice (n = 19), thus ten of the AD mice and ten of the NT mice received an experimental TBI, while the remaining nine mice in each of the AD and NT groups received sham surgery. ", "At two and six weeks after surgery, all mice were tested in the same water maze task.", "\n\nSurgical Procedures {#s2d}\n-------------------\n\nPresymptomatic AD and NT mice were subjected to unilateral moderate TBI using the CCI model (Pittsburgh Precision Instruments, Inc, USA). ", "Animals were deeply anesthetized using the intraperitoneal injection of a combination of ketamine (100 mg/Kg) and xylazine (10 mg/Kg). ", "Once deep anesthesia was achieved, individual animals were fixed in a stereotaxic frame (David Kopf Instruments, Tujunga, CA, USA). ", "After exposing the skull, a 4.0 mm craniectomy was performed over the right frontoparietal cortex (**−**2.0 mm anteroposterior and +2.0 mm mediolateral to bregma) [@pone.0078851-Paxinos1]. ", "The pneumatically operated TBI device impacted the brain at a velocity of 6.0 m/s reaching a depth of 1.0 mm below the dura mater layer, and impacted the brain for 150 ms. ", "The impactor rod was angled 15° to the vertical to maintain a perpendicular position in reference to the tangential plane of the brain curvature at the impact surface [@pone.0078851-Yu1]. ", "A linear variable displacement transducer (Macrosensors, Pennsauken, NJ) measured impact velocity and duration. ", "Mortality associated with this experimental TBI was about 5%, with no significant differences between AD and NT mice.", "\n\nPost-surgery Procedures {#s2e}\n-----------------------\n\nPost-TBI behavioral testing sessions for cohort 1 were conducted two and six weeks after the TBI procedure. ", "The procedures were the same as the pre-TBI training, except that the post-TBI testing consisted of four consecutive sessions (days) regardless of the behavioral performance. ", "Directly following the completion of the final post-TBI testing session, neurological functioning for all groups was assessed using balance beam and visual cliff tasks [@pone.0078851-Arendash1]. ", "A schematic diagram of experimental design is shown ([Figure 1](#pone-0078851-g001){ref-type=\"fig\"}).", "\n\n![", "Experimental design is shown.\\\nFor cohort 1, animals were trained in the RAWM prior to TBI surgery and then tested for cognitive deficits in the RAWM at two and six weeks post-TBI. ", "For cohort 2, there was no pre-TBI behavioral training or post-TBI behavioral testing. ", "All the animals were euthanized at six weeks post-TBI and the brains were harvested for histological analysis.](pone.0078851.g001){#pone-0078851-g001}\n\nFixation and Sectioning {#s2f}\n-----------------------\n\nFor cohort 1, at six weeks post-TBI, mice were deeply anesthetized with 1--2% ketamine and xylazine and perfused from the ascending aorta with 20 mL of cold phosphate buffer saline (PBS) followed by 20 mL of 4% paraformaldehyde in phosphate buffer (PB). ", "Brains were removed and post-fixed in the same fixative for two days followed by 30% sucrose in PB until the brains sank completely. ", "The brains were frozen and cut in transverse sections at 30 µm on a sliding freezing microtome. ", "Every 200 µm tissues were mounted on slides and stained with cresyl violet. ", "All slides were dehydrated with an ethanol series, cleared with Citrisolv (Fisher Scientific, Fair Lawn, N.J.) and coverslipped with Permount (Fisher Scientific, Fair Lawn, N.J.) for lesion site/size analysis.", "\n\nFor cohort 2, animals and their brains were processed identically to cohort 1 at six weeks following TBI. ", "Free floating sections were washed three times for five minutes in PBS containing 0.1% Tween 20 (PBST) (Sigma). ", "For Aβ and MAP2 staining, brain sections were blocked for 60 minutes at room temperature with 5% normal goat serum (Invitrogen, CA) in PBST. ", "Sections were then incubated overnight at 4°C with rabbit polyclonal anti-Aβ 1-14 (1∶100; Abcam, ab2539) and mouse monoclonal anti-MAP2 (1∶100; Abcam ab11267), with 5% normal goat serum. ", "The rabbit anti-Aβ antibody used in this study identifies amino acid residues 1--14 of Aβ and stains extracellular aggregates of Aβ peptides. ", "MAP2, or Microtubule-associated protein 2, typically used as a marker for neurons, is a neuronal phosphoprotein that regulates the structure and stability of microtubules, neuronal morphogenesis, cytoskeleton dynamics and organelle trafficking in axons and dendrites.", "\n\nThe sections were washed five times for 10 minutes in PBST and then soaked in 5% normal goat serum, diluted in PBST, containing the corresponding secondary antibodies (goat anti-rabbit IgG-Alexa 488 (green) and goat anti-mouse IgG-Alexa 594 (red) (1∶500; Invitrogen) for 90 minutes. ", "Finally, sections were washed five times for 10 minutes in PBST and three times for five minutes in PBS, then processed for Hoechst 33258 (bisBenzimideH 33258 trihydrochloride, Sigma) for 30 minutes, washed in PBS, then cover-slipped with Fluoromount (Sigma).", "\n\nHistological analyses {#s2g}\n---------------------\n\nFor cohort 1, the lesion sites were microscopically confirmed using a macroscope (Wild M420 and Nikon SMZ 1500) and a microscope (Nikon Microphot FX). ", "Images of sections with the interval of 400 µm were traced using a camera lucida method. ", "Cortical, hippocampal, and overall lesion volumes were determined by calculating the total volumes of neuronal loss in the injured hemisphere compared to the contralateral side.", "\n\nFor cohort 2, the number of extracellular Aβ deposits and MAP2 positive cells in the cortex and hippocampus were examined using an Olympus confocal microscope (Japan). ", "Every sixth 30 µm-thick coronal tissue section was collected from each mouse. ", "The number of extracellular Aβ deposits and MAP2 positive cells were counted in each of five high power fields (HPF) (200,000 µm^2^) and the averages were used for the statistical analyses. ", "The regions of interest for estimation of extracellular Aβ deposition and MAP2 positive cells included the ccortex and the hippocampus, which were photographically captured (Axiophot2; Zeiss), and cells were quantified by counting per HPF view selected at random and corrected by the Abercrombie formula. ", "Two captured fields in each coronal level, using three levels, were used to analyze the extracellular Aβ deposition and MAP2 positive cells in the cortex (AP, 1.5, 0.5, and −0.5 mm to bregma) and hippocampus (AP, −4.8, −5.3, and −5.8 mm) [@pone.0078851-Paxinos1], using Scion Image software (Scion, Frederick, MD). ", "Binary images were created using a distinct threshold, and then the positive areas were calculated [@pone.0078851-Baldauf1]. ", "Additionally, confocal analysis was performed using confocal microscope (Olympus).", "\n\nStatistical Analysis {#s2h}\n--------------------\n\nAll genotype/TBI groups were assessed statistically using IBM SPSS Statistics software. ", "For the multiple post-TBI RAWM sessions, a 2×2 ANOVA was conducted with genotype (AD, NT) and TBI exposure (TBI, Sham) as the between-subjects factors. ", "The errors of T4 and T5 were the dependent variables focused on to measure behavioral deficit. ", "For the neurological assessment tasks, a 2×2 ANOVA (genotype x TBI exposure) was used to measure any group differences in the balance beam, and a Kruskal-Wallis test was used for the visual cliff task. ", "Upon observing any significant differences between groups, subsequent t-tests were also conducted. ", "All group comparisons having p\\<0.05 were considered significant.", "\n\nResults {#s3}\n=======\n\nLesion Volume {#s3a}\n-------------\n\nAll lesions were made in the right hemisphere of TBI animals. [", "Figure 2A](#pone-0078851-g002){ref-type=\"fig\"} shows two examples, in which damage was observed in the cortex, hippocampus, and subcortical structures to some degree. ", "For cohort 1, there were no significant differences of lesion volume between AD- and NT-TBI mice, for the cortex, hippocampal area, subcortical area or overall lesion volume (p\\'s \\> 0.05). ", "In addition, there was no detectable reduction in brain volume of non-lesioned AD mice compared to non-lesioned NT mice. [", "Figure 2B](#pone-0078851-g002){ref-type=\"fig\"} shows the mean lesion volumes of these structures.", "\n\n![", "Two examples of lesion reconstructions for an AD- and NT-TBI mouse (A).\\\nEach figure is composed of transverse sections from anterior to posterior. ", "Each section is color-coded to show the cortex (green), hippocampus (yellow), and subcortical areas (magenta). ", "The lesion volumes for NT-TBI (yellow) and AD-TBI (blue) mice (**B**). ", "There were no significant differences of lesion volume between NT-and AD-TBI mice. ", "The error bars represent the SEM.](pone.0078851.g002){#pone-0078851-g002}\n\nPre-TBI RAWM Performance {#s3b}\n------------------------\n\nBefore TBI was performed, 19 AD and 19 NT mice were trained to perform in the RAWM over a 14 day period. ", "Compared to their performance during naïve trial 1 (T1) of the final two-day block, AD and NT groups both were able to significantly improve performance during trial 4 (T4) and trial 5 (T5) ([Figure 3A](#pone-0078851-g003){ref-type=\"fig\"}). ", "Mice in both AD and NT groups performed at an average of around two or fewer errors across T4 and T5 during this final two-day block. ", "Thus, AD and NT groups performed similarly in their learning (T4) and memory retain (T5) prior to surgery.", "\n\n![", "Prior to TBI surgery (A), the number of errors on trial 1 (T1), trial 4 (T4), and the 30 minute retention trial (T5) for NT (yellow) and AD (blue) mice during the final two days of RAWM testing.\\\nAsterisk indicates significant improvement from T1 for that group at p\\<0.05 or higher level of significance. ", "For Post-TBI testing, the number of errors on T1, T4, T5 for the RAWM at two weeks (**B**) and six weeks (**C**) after TBI. ", "NT-Sham (hatched yellow, n = 9), NT-TBI (solid yellow, n = 10), AD-Sham (hatched blue, n = 8), and AD-TBI (solid blue, n = 7) mice. ", "Single asterisk indicates the AD-TBI group is significantly different from all other groups at p\\<0.02. ", "Double asterisk indicates the AD-TBI group is significantly different from AD-Sham at p\\<0.01. ", "The error bars represent the SEM.](pone.0078851.g003){#pone-0078851-g003}\n\nAnimals in each genotype were then divided into the TBI and sham lesion groups to counterbalance learning performance. ", "The mean number of errors were compared for NT-Sham (n = 9), NT-TBI (n = 10), AD-Sham (n = 9), and AD-TBI (n = 10) mice. ", "A 2×2 Factorial ANOVA was conducted with genotype (NT, AD) and planned surgical treatment (TBI, Sham) for T1, T4 and T5. ", "For T1, T4, and T5 there were no significant effects for genotype, treatment, or interaction (p\\'s \\> 0.05).", "\n\nPost-TBI RAWM Performance {#s3c}\n-------------------------\n\nFor the RAWM task, two weeks after TBI exposure, there were no significant effects in T1 for genotype, TBI exposure, or interaction of genotype by TBI exposure (p\\'s \\> 0.05), indicating that all groups had the same random performance on this first trial of daily testing. ", "For T4, genotype (F~1,33~ = 5.906, p = .021), TBI exposure (F~1,33~ = 4.927, p = .034), and a genotype by TBI exposure interaction (F~1,33~ = 7.167, p = .012), all supported the significant effect of impact of TBI on AD mice performance (p\\<0.02; asterisk on [Figure 3B](#pone-0078851-g003){ref-type=\"fig\"}). ", "TBI had no effect on performance of NT mice during T4 (p \\> 0.05). ", "In contrast, TBI induced impairement in performance in AD mice during the same trial compared to AD-Sham mice, as indicated by their sharply higher number of errors during this trial (t~13~ = 2.989, p = .01). ", "However, in T5, AD-TBI mice performed similar to controls; there was no main effect for genotype, TBI exposure, or interaction of genotype by TBI exposure (p\\'s \\> 0.05).", "\n\nSix weeks after TBI exposure ([Figure 3C](#pone-0078851-g003){ref-type=\"fig\"}), there were significant effects for TBI exposure in T1 (F~1,33~ = 4.535, p = .042). ", "During this first trial, TBI mice made more errors than mice without TBI (t~32~ = 2.386, p = .023), but there were no significant effects for genotype (p \\> 0.05). ", "For T4, there was a main effect in terms of genotype (F~1,33~ = 4.441, p = .044), TBI exposure (F~1,33~ = 4.998, p = .033), and interaction of genotype by TBI exposure (F~1,33~ = 6.641, p = .015). ", "The AD-TBI mice made significantly more errors than all other groups (p\\<0.02; asterisk on [Figure 3C](#pone-0078851-g003){ref-type=\"fig\"}): AD-Sham mice (t~13~ = 2.979, p = .011); NT-TBI (t~15~ = 3.311, p = .005); NT-Sham (t~14~ = 2.977, p = .010). ", "For T5, there were no significant differences between AD and NT groups (p \\> 0.05). ", "However, there were significant effects for TBI exposure (F~1,33~ = 6.950, p = .013) and the interaction of genotype by TBI exposure (F~1,33~ = 5.269, p = .029). ", "Specifically, AD-TBI mice made more errors than AD-Sham mice (t~13~ = 4.533, p = .001). ", "In sharp contrast, NT-TBI mice had the same low level of T5 errors compared to NT-Sham mice (p \\> 0.05). ", "However there were no differences between TBI groups (p \\> 0.05). ", "Moreover, all groups were able to significantly improve their performance except for the AD-TBI group, across trials T1 vs. T4 and T1 vs. T5 (p\\'s \\> 0.05), thus indicating a cognitive impairment specific for the AD-TBI group at this six week time point.", "\n\nConcerning neurological evaluation (data not shown), there were no group differences in the balance beam task for genotype, TBI exposure, or interaction of genotype by TBI exposure (p\\'s \\> 0.05). ", "For the visual cliff task, there were also no significant group differences (p \\> 0.05).", "\n\nTBI expedites extracellular Aβ aggregation in the cortex of AD-transgenic mice {#s3d}\n------------------------------------------------------------------------------\n\nAβ staining demonstrated that more extracellular Aβ deposits were found in the cortex of the AD-TBI group ([Figure 4A, C](#pone-0078851-g004){ref-type=\"fig\"}). ", "Of note, MAP2 positive cells showed decrease in the cortex of the AD-TBI group ([Figure 4B, C](#pone-0078851-g004){ref-type=\"fig\"}). ", "ANOVA revealed significant treatment effects on extracellular Aβ deposits in the cortex (F~3,69~ = 11.629, p\\<0.0001) ([Figure 4A](#pone-0078851-g004){ref-type=\"fig\"}). ", "Immunostaining revealed a significant increase in extracellular Aβ deposits in the cortex of the AD-TBI group (6.44±1.04 deposits/HPF) compared to the NT-TBI group (2.60±0.52 deposits/HPF, p\\<0.01), AD-Sham group (2.00±0.49 deposits/HPF, p\\<0.001) and NT-Sham group (0.20±0.20 deposits/HPF, p\\<0.0001) ([Figure 4A, C](#pone-0078851-g004){ref-type=\"fig\"}). ", "Along these same lines, the NT-TBI group also exhibited a significant increase in extracellular Aβ deposits in the cortex compared to the AD-Sham group (p\\<0.001) and NT-sham group (p\\<0.001) ([Figure 4A](#pone-0078851-g004){ref-type=\"fig\"}). ", "In addition, ANOVA detected significant treatment effects on MAP2 neuronal cell loss in the cortex (F~3,34~ = 11.553, p\\<0.0001). ", "Of note, there was a significant decrease in MAP2 positive cells in the cortex of the AD-TBI group (47.20±11.00 neurons/ HPF) compared to the AD-Sham group (101.33±11.68 neurons/ HPF, p\\<0.01) and NT-Sham group (133.71±20.00 neurons/ HPF, p\\<0.01) ([Figure 4B](#pone-0078851-g004){ref-type=\"fig\"}). ", "Similarly, the NT-TBI group also exhibited a significant MAP2 neuronal cell loss in the cortex (53.13±7.19 neurons/ HPF) compared to the AD-Sham group (p\\<0.01) and NT-Sham group (p\\<0.01). ", "There was no significant difference between AD-TBI and NT-TBI groups (p\\>0.05) ([Figure 4B](#pone-0078851-g004){ref-type=\"fig\"}).", "\n\n![", "TBI accelerated extracellular Aβ deposits in the cortex of AD mice that received TBI.\\\nStatistical analysis revealed a significant increase in extracellular Aβ deposits in the cortex of AD mice that received TBI compared to the NT mice that received TBI and the AD and NT mice that underwent sham surgery (Panel A). ", "Statistical analysis revealed that there was a significant decrease in the number of MAP2 positive cells in the cortex of AD-transgenic and NT mice that underwent TBI surgery compared to the AD and NT mice that received sham surgery (Panel B). ", "Immunofluorescence for the detection of extracellular Aβ deposits and MAP2 (Panel C). ", "Scale bars = 50 µm. ", "The insets correspond to representative high magnifications of MAP2 images. ", "Scale bars = 100 µm. ", "The brain illustration shows the location of the brain slices chosen for histological analysis. \\*\\* ", "p \\< 0.01, \\*\\*\\* p \\< 0.001, \\*\\*\\*\\* p \\< 0.0001.](pone.0078851.g004){#pone-0078851-g004}\n\nTBI accelerates extracellular Aβ deposition in the hippocampus of AD-transgenic mice {#s3e}\n------------------------------------------------------------------------------------\n\nAβ staining demonstrated that more extracellular Aβ deposits were found in the hippocampus of the AD-TBI group ([Figure 5A, C](#pone-0078851-g005){ref-type=\"fig\"}). ", "Of note, MAP2 positive cells showed decrease in the hippocampus of the AD-TBI group ([Figure 5B, C](#pone-0078851-g005){ref-type=\"fig\"}). ", "ANOVA revealed significant treatment effects on the number of extracellular Aβ deposits in the hippocampus (F~3,57~ = 33.686, p\\<0.0001) ([Figure 5A](#pone-0078851-g005){ref-type=\"fig\"}). ", "There was a significant increase in the number of extracellular Aβ deposits in the hippocampus of the AD-TBI group (50.18±7.70 deposits/HPF), compared to those of the NT-TBI group (14.12±2.08 deposits/HPF, p\\<0.001), AD-Sham group (3.00±1.09 deposits/HPF, p\\<0.0001), and NT-Sham group (2.82±2.43 deposits/HPF, p\\<0.0001) ([Figure 5A](#pone-0078851-g005){ref-type=\"fig\"}). ", "Along these same lines, the NT-TBI group also exhibited a significant increase in extracellular Aβ deposits in the hippocampus compared to the AD-Sham group (p\\<0.0001) and NT-Sham group (p\\<0.01) ([Figure 5A](#pone-0078851-g005){ref-type=\"fig\"}). ", "In parallel, ANOVA revealed significant treatment effects on MAP2 neuronal cell loss in the hippocampus (F~3,42~ = 3.711, p\\<0.05). ", "The number of MAP2 positive cells in the hippocampus was significantly lower in the AD-TBI group (27.00±2.53 neurons/HPF) compared to the AD-sham group (39.00±3.16 neurons/HPF, p\\<0.01) and NT-Sham group (53.81±9.49 neurons/HPF, p\\<0.05) ([Figure 5B](#pone-0078851-g005){ref-type=\"fig\"}). ", "Conversely, for the NT-TBI group (36.25±3.92 neurons/HPF) there was no significant difference in MAP2 positive cells when compared to the AD-Sham group (p\\>0.05) and NT-Sham group (p\\>0.05) ([Figure 5B](#pone-0078851-g005){ref-type=\"fig\"}).", "\n\n![", "TBI accelerated extracellular Aβ deposits in the hippocampus of AD-TBI mice.\\\nStatistical analysis revealed a significant upregulation of extracellular Aβ deposits in the AD mice that received TBI compared to the NT mice that received TBI and the AD and NT mice that received sham surgery (Panel A). ", "MAP2 staining revealed a significant decrease of MAP2 positive cells in the hippocampus of AD mice that received TBI compared to the AD and NT mice that received sham surgery (Panel B). ", "Immunofluorescence for the detection of extracellular Aβ deposits and MAP2 (Panel C). ", "Scale bars = 50 µm. ", "The insets correspond to representative high magnifications of MAP2 images. ", "Scale bars  = 100 µm. ", "The brain illustration shows the location of the brain slices chosen for histological analysis. \\* ", "p \\< 0.05, \\*\\* p \\< 0.01, \\*\\*\\* p \\< 0.001, \\*\\*\\*\\* p \\< 0.0001.](pone.0078851.g005){#pone-0078851-g005}\n\nDiscussion {#s4}\n==========\n\nThis study reports a causal role of TBI in AD-related pathological manisfestations. ", "We demonstrate accelerated Aβ aggregations in the APP/PS1 transgenic mice at six weeks post-TBI accompanied by expedited cognitive impairment in presymptomatic AD mice. ", "The recognition of this direct link between TBI and AD should aid in developing novel treatments directed at abrogating cellular injury and Aβ deposition in the TBI brain.", "\n\nFor cohort 1, AD mice with TBI made significantly more errors in the RAWM task than controls (i.e., AD mice without TBI and NT mice with or without TBI). ", "Because there were no lesion volume differences between AD-TBI and NT-TBI mice, the deficits were unlikely to be due to the lesion size per se. ", "Therefore, the results suggest that TBI precipitated cognitive deficits specifically in presymptomatic AD mice, but not NT mice. ", "The deficits of AD-TBI mice were found in T4, but not T5, at two weeks post-TBI surgery, whereas the deficits were seen in both T4 and T5 at six weeks post-TBI. ", "It is not clear why the behavioral effects in T5 were different between the two and six weeks post-TBI. ", "However, one possibility is that TBI-induced extracellular Aβ deposits increased substantially between the two and six week behavioral test points. ", "Another issue that warrants further studies is the significance of the morphological distortion of the brain structures caused by TBI. ", "We noted that TBI resulted in changes of the shape and location of some brain structures, including the hippocampus. ", "Although we measured the volume changes, we did not quantitatively analyze the gross morphological changes. ", "Thus, it is possible that some axonal damage due to TBI was overlooked in our analyses.", "\n\nThe increase in extracellular Aβ deposits in the cortex and hippocampus of AD mice that received TBI surgery supports the notion that TBI induces the upregulation of enzymes activating the cleavage of amyloid precursor protein to Aβ [@pone.0078851-Davies1]--[@pone.0078851-Palmer1] ([Figure 4](#pone-0078851-g004){ref-type=\"fig\"}, [5](#pone-0078851-g005){ref-type=\"fig\"}). ", "Although the histological damage induced by the TBI only directly affected the cortical region of the brain, extracellular Aβ deposition was detected throughout the cortex and the hippocampus of the AD mice. ", "These results implicate an evolving cell death beyond the initial localized cortical damage induced by TBI. ", "Vascular damage caused by TBI may play a critical role in the exacerbation of AD-like histopathology following TBI as seen in laboratory [@pone.0078851-Aliev1], [@pone.0078851-Jantaratnotai1] and clinical studies [@pone.0078851-Aliev1]--[@pone.0078851-Yesil1]. ", "The breakdown of vasculature patency after TBI contributing to the acceleration of Aβ deposition in AD is thought to be mediated by a pro-inflammatory signaling pathway [@pone.0078851-Walker1] which is a major pathological component of TBI [@pone.0078851-Pettus1], [@pone.0078851-You1].", "\n\nThe results of this study have important clinical implications. ", "Accelerated AD symptoms following TBI suggest that trauma is a major co-morbidity factor of AD. ", "Of note, the risk of developing AD after severe TBI is significantly higher in individuals that lack the ApoEε4 allele [@pone.0078851-Jellinger1]. ", "The military population is at an increased risk of TBI, and accumulating evidence indicates similarly a trend of higher incidence of cognitive decline in soldiers with direct or even indirect exposure to TBI [@pone.0078851-Bryan1]. ", "Accordingly, soldiers diagnosed with TBI, including mild TBI, may benefit from a regimen of AD medications to prevent the development of AD-like pathology.", "\n\nIn summary, we demonstrated that TBI expedites the presentation of AD-like cognitive deficits and histological pathology in transgenic mice. ", "A recent paper [@pone.0078851-Tran1] reported that the CCI TBI model promoted 3xTg-AD mice to display intra-axonal Aβ accumulations and increased phospho-tau immunoreactivity at 24 hours and up to seven days after TBI. ", "The present study replicated the observed acceleration of Aβ aggregation [@pone.0078851-Tran1], but also extended such AD pathology up to six weeks post-TBI. ", "Our observed histological data should allow correlative analyses between extracellular Aβ deposits and cognitive impairments providing further support for a causal role of TBI in AD-related pathology. ", "Finding novel treatments designed to limit cellular injury and reduce extracellular Aβ deposition in the brain may prove beneficial in AD and TBI.", "\n\n[^1]: **Competing Interests:**Co-author GWA is employed by NeuroEM Therapeutics, Inc.,. ", "CVB is supported by National Institutes of Health, National Institute of Neurological Disorders and Stroke 1R01NS071956-01, James and Esther King Foundation for Biomedical Research Program, SanBio Inc., Celgene Cellular Therapeutics, KMPHC and NeuralStem Inc. Senior author Dr. Cesar Borlongan is a PLOS ONE Editorial Board member. ", "This does not alter the authors\\' adherence to all the PLOS ONE policies on sharing data and materials.", "\n\n[^2]: Conceived and designed the experiments: NT SLK TS GWA CVB. ", "Performed the experiments: NT SLK TS CVB. ", "Analyzed the data: NT SLK TS GWA CVB. ", "Contributed reagents/materials/analysis tools: TS GWA CVB. ", "Wrote the paper: NT SLK TS GWA CVB.", "\n" ]
{ "pile_set_name": "PubMed Central" }
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[ "/*\r\n ==============================================================================\r\n\r\n This file is part of the JUCE library.", "\r\n Copyright (c) 2017 - ROLI Ltd.\r\n\r\n JUCE is an open source library subject to commercial or open-source\r\n licensing.", "\r\n\r\n By using JUCE, you agree to the terms of both the JUCE 5 End-User License\r\n Agreement and JUCE 5 Privacy Policy (both updated and effective as of the\r\n 27th April 2017).", "\r\n\r\n End User License Agreement: www.juce.com/juce-5-licence\r\n Privacy Policy: www.juce.com/juce-5-privacy-policy\r\n\r\n Or: You may also use this code under the terms of the GPL v3 (see\r\n www.gnu.org/licenses).", "\r\n\r\n JUCE IS PROVIDED \"AS IS\" WITHOUT ANY WARRANTY, AND ALL WARRANTIES, WHETHER\r\n EXPRESSED OR IMPLIED, INCLUDING MERCHANTABILITY AND FITNESS FOR PURPOSE, ARE\r\n DISCLAIMED.", "\r\n\r\n ==============================================================================\r\n*/\r\n\r\nnamespace juce\r\n{\r\n\r\nArrowButton::ArrowButton (const String& name, float arrowDirectionInRadians, Colour arrowColour)\r\n : Button (name), colour (arrowColour)\r\n{\r\n path.addTriangle (0.0f, 0.0f, 0.0f, 1.0f, 1.0f, 0.5f);\r\n path.applyTransform (AffineTransform::rotation (float_Pi * 2.0f * arrowDirectionInRadians, 0.5f, 0.5f));\r\n}\r\n\r\nArrowButton::~ArrowButton() {}\r\n\r\nvoid ArrowButton::paintButton (Graphics& g, bool /*isMouseOverButton*/, bool isButtonDown)\r\n{\r\n Path p (path);\r\n\r\n const float offset = isButtonDown ? ", "1.0f : 0.0f;\r\n p.applyTransform (path.getTransformToScaleToFit (offset, offset, getWidth() - 3.0f, getHeight() - 3.0f, false));\r\n\r\n DropShadow (Colours::black.withAlpha (0.3f), isButtonDown ? ", "2 : 4, Point<int>()).drawForPath (g, p);\r\n\r\n g.setColour (colour);\r\n g.fillPath (p);\r\n}\r\n\r\n} // namespace juce\r\n" ]
{ "pile_set_name": "Github" }
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[ "RIM adds 15,000 new BlackBerry 10 apps in one weekend\n\nCrisp $100 bills waved in devs' faces\n\nResearch in Motion's BlackBerry App World store gained a healthy new crop of apps over the weekend, thanks to the company's \"Port-a-thon\" promotion, which offered developers $100 apiece to bring their existing apps to the BlackBerry 10 platform.", "\n\nIn a Twitter post late Saturday night, Alec Saunders, RIM's VP of developer relations, announced that the mini-contest had brought in 15,000 new app submissions in just 37.5 hours.", "\n\nThat sudden influx could boost the total number of apps available in the store when RIM launches its first BlackBerry 10 handsets on January 30. ", "Last week, RIM chief marketing officer Frank Boulben promised that at least 70,000 apps would be ready by launch date, although CEO Thorsten Heins had earlier projected as many as 100,000.", "\n\nHaving a well-stocked app store is widely perceived as being essential for the success of any mobile platform. ", "Apple, by far the leader in this category, boasts some 775,000 apps in its iOS App Store, and the Google Play store has nearly as many.", "\n\nBut platforms other than the Big Two have struggled to win much developer support. ", "Microsoft only claims to host 120,000 apps in its Windows Phone store, despite the fact that it has been around since the days of Windows Phone 7. ", "For RIM to have managed to drum up nearly 100,000 apps for what is essentially a brand new platform is a fairly impressive achievement.", "\n\nwell there you have it.37.5 hours in, we hit 15,000 apps for this portathon.", "Feel like I've run a marathon.", "Thanks to all the devs!", "\n\nMuch of the credit for that success goes to Saunders, who since joining RIM in 2011 has pulled out all the stops to get developers involved with BlackBerry 10, even going so far as to record a motivational song and video.", "\n\nFun and games aside, Saunders' message to developers boils down to what is arguably the most effective incentive of all: money. ", "If the Port-a-thon promotion – offering developers a measly $100 for each app they port – seems a little tight-fisted, that's only because it's a last-minute incentive.", "\n\nEarlier, RIM offered developers an unusual guarantee: if a developer manages to break the $1,000 revenue mark in BlackBerry App World, RIM will guarantee that they will earn at least $10,000 – that is, if their sales after one year total less than $10,000, RIM will make up the difference.", "\n\nTime will tell how often RIM will be forced to make good on that offer. ", "In the meantime, developers who missed out on this weekend's Port-a-thon event have one more chance to port their apps to BlackBerry 10 and pocket $100.", "\n\nThe final \"BlackBerry 10 Last Chance Port-A-Thon\" will begin on January 18 and will run for 36 hours. ", "It's a virtual event, so anyone can register to enter. ", "Developers earn $100 for each app entered and approved, up to a maximum of 20 apps. ", "Developers who submit five or more apps are automatically entered into a drawing for a new BlackBerry 10 handset. ", "®" ]
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[ "Pages\n\nFollowers\n\nThursday, February 4, 2010\n\nHave you heard the cloth diaper song!?", "\n\nlove it!! ", "It’s by Mr. Mike Sings and it’s called I Use Cloth. ", "Way cute!", "\n\nMy favorite line => “My baby’s backside is cute even if it’s covered in poop.” ", "HAHAHA\n\nHere are the lyrics:\n\nYour baby poops and your baby pees,Every time she sits on your knees.", "You want solutions? ", "You want answers? ", "Well, I got ‘em.", "Stop letting that child crawl around your house bare-bottomed.", "\n\nTry those disposables; Look, Ma, no more tears.", "So what if they sit in a landfill for so, so many years?But there’s something else out there for you,If you want to give it a try.", "They can fit on your newborn, your crawler, your walker,Or you can buy ‘em, One Size.", "\n\nTry using cloth – they’re amazing.", "And they come in different colors.", "If you use cloth, imagine the savings.", "Don’t worry if you annoy your mother.", "\n\nThere are so many styles to try.", "There are so many brands to buy.", "If you use cloth, the limit’s the sky.", "And I can’t imagine why,You wouldn’t use cloth.", "\n\nThey’re great for when I’m at home or when I go outside.(I use cloth)My baby’s bottom isn’t something I’m always trying to hide.(I use cloth)They’re great for during the day.", "They’re absorbent for overnight, too.(I use cloth)My baby’s backside is cute even if it’s covered in poo.", "\n\nI gotta tell you something, darling, that don’t worry me:I don’t mind it at all when my baby poops or pees.", "I got something so soft and snuggly on my baby’s bottom.", "I don’t need no diaper pins, no rubber pants – so don’t think I forgot ‘em.", "\n\n3. ", "tUNggU for an email/reply (dLm 24 jAm) on the availability on the item(s).4. ", "Confirmation will be made including item(s) cost and postage fees.5. ", "Please bank in the total amount to our Maybank Account Number kAt pAYmEnT mEThOD aLSO..(this aCC nO will be given in confirmation email).6. ", "Please inform us after the payment has been made (including referral number).", "\n\n7. ", "After confirmation of the payment, we will delivery the item(s) to you.", "\n\nTERMS AND CONDITION\n\nSERIOUS BUYERS ONLY PLEASE~\nMamaCygBaby will not be (tIDAk akAn) responsible for any lost or damage during delivery.", "\nImPOrTaNt !!!!:", "\nNo refundable or exchangeable for the items that you has been purchased.", "\nThaNk YoU...\n** DISCOUNT will be giveN for thosE that buY anY item(s) and aNY nUmbers of item froM uS and free gift for customer that buy from us more thaN RM 100 excluded shipPing coSt....so??HurrY!huRrY!!", "\nFOr CustOmer InformtioN:\ni'll try To Give My Customer thE besT priCe~~\nThaNk You\nMamaCygBaby\n\nThursday, February 4, 2010\n\nHave you heard the cloth diaper song!?", "\n\nlove it!! ", "It’s by Mr. Mike Sings and it’s called I Use Cloth. ", "Way cute!", "\n\nMy favorite line => “My baby’s backside is cute even if it’s covered in poop.” ", "HAHAHA\n\nHere are the lyrics:\n\nYour baby poops and your baby pees,Every time she sits on your knees.", "You want solutions? ", "You want answers? ", "Well, I got ‘em.", "Stop letting that child crawl around your house bare-bottomed.", "\n\nTry those disposables; Look, Ma, no more tears.", "So what if they sit in a landfill for so, so many years?But there’s something else out there for you,If you want to give it a try.", "They can fit on your newborn, your crawler, your walker,Or you can buy ‘em, One Size.", "\n\nTry using cloth – they’re amazing.", "And they come in different colors.", "If you use cloth, imagine the savings.", "Don’t worry if you annoy your mother.", "\n\nThere are so many styles to try.", "There are so many brands to buy.", "If you use cloth, the limit’s the sky.", "And I can’t imagine why,You wouldn’t use cloth.", "\n\nThey’re great for when I’m at home or when I go outside.(I use cloth)My baby’s bottom isn’t something I’m always trying to hide.(I use cloth)They’re great for during the day.", "They’re absorbent for overnight, too.(I use cloth)My baby’s backside is cute even if it’s covered in poo.", "\n\nI gotta tell you something, darling, that don’t worry me:I don’t mind it at all when my baby poops or pees.", "I got something so soft and snuggly on my baby’s bottom.", "I don’t need no diaper pins, no rubber pants – so don’t think I forgot ‘em.", "\n\nNo comments:\n\nPost a Comment\n\nThursday, February 4, 2010\n\nHave you heard the cloth diaper song!?", "\n\nlove it!! ", "It’s by Mr. Mike Sings and it’s called I Use Cloth. ", "Way cute!", "\n\nMy favorite line => “My baby’s backside is cute even if it’s covered in poop.” ", "HAHAHA\n\nHere are the lyrics:\n\nYour baby poops and your baby pees,Every time she sits on your knees.", "You want solutions? ", "You want answers? ", "Well, I got ‘em.", "Stop letting that child crawl around your house bare-bottomed.", "\n\nTry those disposables; Look, Ma, no more tears.", "So what if they sit in a landfill for so, so many years?But there’s something else out there for you,If you want to give it a try.", "They can fit on your newborn, your crawler, your walker,Or you can buy ‘em, One Size.", "\n\nTry using cloth – they’re amazing.", "And they come in different colors.", "If you use cloth, imagine the savings.", "Don’t worry if you annoy your mother.", "\n\nThere are so many styles to try.", "There are so many brands to buy.", "If you use cloth, the limit’s the sky.", "And I can’t imagine why,You wouldn’t use cloth.", "\n\nThey’re great for when I’m at home or when I go outside.(I use cloth)My baby’s bottom isn’t something I’m always trying to hide.(I use cloth)They’re great for during the day.", "They’re absorbent for overnight, too.(I use cloth)My baby’s backside is cute even if it’s covered in poo.", "\n\nI gotta tell you something, darling, that don’t worry me:I don’t mind it at all when my baby poops or pees.", "I got something so soft and snuggly on my baby’s bottom.", "I don’t need no diaper pins, no rubber pants – so don’t think I forgot ‘em." ]
{ "pile_set_name": "Pile-CC" }
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0.002156
5
[ "word-forming element meaning \"mind, mental; spirit, unconscious,\" from Greek psykho-, combining form of psykhe (see psyche). ", "It also was used to form compounds in Greek, e.g. psychopates \"soul-beguiling.\"" ]
{ "pile_set_name": "Pile-CC" }
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[ "Tarutung\n\nTarutung (Dutch: Taroetoeng) is a town in the Tapanuli Utara district and the seat (capital) of North Tapanuli Regency, North Sumatra, Sumatra, Indonesia. ", "\n\nTarutung in Batak language means durian and town was named after the durian trees that grow there.", "\n\nExternal links\nView of Taroetoeng circa 1925 University of Leiden\n\nCategory:Batak\nCategory:Regency seats of North Sumatra" ]
{ "pile_set_name": "Wikipedia (en)" }
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[ "Q:\n\nTrouble when adding a lot of Controls to a .NET Windows Form (C#)\n\nI have a Windows Form app written in C#. ", " Its job is to send messages to a list of users. ", "While those messages are being sent, I'd like to display status of the operation for each user. ", " What I am doing (for each user) is creating a Label control and adding it to Panel. ", " This works without a problem for a small set of users. ", " When I increase the size to 1000 or more, the Visual Studio Debugger displays the following message:\n\nA first chance exception of type 'System.", "ComponentModel.", "Win32Exception' occurred in\n System.Windows.Forms.dll A first chance exception of type\n 'System.", "Reflection.", "TargetInvocationException' occurred in\n mscorlib.dll\n\nAnd then the application hangs. ", " Any thoughts on what I'm doing wrong and how I can fix this?", "\n\nA:\n\nUse DataGridView instead\n\nA:\n\nGiven the size, I would consider displaying your status in a RichTextBox. ", "\nWhat is happening is that you are generating too many handles and the Framework can't handle them all.", "\n\n" ]
{ "pile_set_name": "StackExchange" }
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0.006736
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[ "Inhibition of plasminogen activators by conditioned medium of human hepatocytes and hepatoma cell line Hep G2.", "\nPrimary cultures of human hepatocytes and the human hepatocellular cell line Hep G2 are shown to produce fast-acting inhibitors of tissue-type plasminogen activator (tPA) and urokinase. ", "The tPA inhibitory activities in conditioned medium of these liver cell types are very similar to those present in human endothelial cell conditioned medium. ", "They are stable at pH 2.5, have similar dissociation constants with tPA (1.5 to 5 pmol/L), and are similar in thermostability. ", "Addition of tPA to conditioned medium of Hep G2 and endothelial cells that has been depleted of tPA and urokinase reveals a 100 kilodalton tPA-inhibitor complex. ", "The fast-acting tPA inhibitory activity in human plasma has comparable properties, and may originate from the liver or the vascular endothelium or both. ", "After sodium dodecyl sulfate-polyacrylamide gel electrophoresis of conditioned medium from hepatocytes, Hep G2, and endothelial cells, additional fibrinolytic inhibition at 52 kilodaltons was visualized. ", "This was not found with human plasma." ]
{ "pile_set_name": "PubMed Abstracts" }
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0.003402
5
[ "[Psychopathology of organic psychoses with reference to differential diagnostic, epidemiologic and morphologic aspects].", "\nFollowing a brief discussion of the historical development of the term \"Organic Psychosis\", detailed consideration is given to the phenomenology and differential diagnosis of this group of diseases. ", "The published epidemiological data is compared to the results of our own study. ", "The cranial CT makes it possible to correlate clinical and morphological findings. ", "In our investigation 72.5% of the patients with severe chronic organic psychosis show considerable brain atrophy. ", "The morphological aspect is a determining factor for the therapeutic measures and for the prognosis." ]
{ "pile_set_name": "PubMed Abstracts" }
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[ "Products >\n\nSolutions >\n\nThe Current State of Mobile App Discovery\n\nMarseille Steele\n\n5 min read\n\nPosted on July 22, 2012\n\nIf you are attending Casual Connect next week in Seattle July 24-26, be sure to attend the lunch time panel The Current State of Mobile App Discovery. ", "InMobi's Kim Carlson will be speaking alongside our colleagues from Papaya Mobile, TapJoy, Google, Iddiction and SoftTech VC. ", "It's no secret that the App industry is in a constant state of evolution. ", "In the last year the growth of smart devices has exploded and, as a result, there are now more than one million active apps. ", "Every day we see advancements in the standardization of development tools, decreasing technology costs, and increased investments in mobile platforms. ", "Everyone wants in on the game, and it becomes more difficult when heavy hitters with deep pockets like Amazon and Facebook become the every-day Developers competition. ", "The panel will address the difficulties on how to build awareness and how to make enough noise in order to rise above thousands of other new apps that enter the market each week. ", "Here at InMobi, we pride ourselves on being a solution provider for the Developer community. ", "So, please join us as we address how the every-day developer can learn the tricks of the trade to make it into the coveted top ten-list '“ and make some money while doing it." ]
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0.008485
5
[ "Countries throughout the world are celebrating May Day, also referred to as International Labor Day. ", "In Russia, the holiday is marked in every big city. ", "In the capital alone, an estimated 120,000 people have shown up.", "\n\nThe holiday is being marked worldwide, starting in the east and following the sun around the globe.", "In Asia, May Day has gone beyond its roots as an international workers' holiday to a day of international protest. ", "Thousands marched in Indonesia, Thailand, Taiwan, South Korea and other countries demanding wage increases and better working conditions.", "In Manila, the Philippines, protesters burnt an effigy of the country’s President Benigno Aquino III during a rally near the Presidential Palace.", "Hundreds of thousands of workers came out onto the streets of the Cuban capital Havana to mark the occasion, with the crowds addressed by various politicians and trade union officials. ", "The holiday is also widely celebrated in much of Europe. ", "Great Britain, France, Germany, Spain and Greece are holding rallies.", "In France, May Day comes just five days before the second and decisive presidential round. ", "Media reports suggest leftists, rightist Union for a Popular Movement and National Front have been holding an indirect battle in the streets of the French capital as they gathered for rival rallies.", "In Spain, where the Euro crisis has seen the country plunge into a double-dip recession, thousands of people took to the streets to voice their anger at the ongoing stringent cuts and unemployment. ", "More than 2,000 Greeks marked the May Day holiday with massive strikes and rallies against tough austerity measures in return for IMF and EU loans. ", "The country’s railways are among those holding a 24-hour strike. ", "They are joined by public transport employees and sea port workers.", "There were brief clashes between protesters and riot police in the Greek capital Athens as well as the Italian city of Turin, but for the most part, global May Day activities have been peaceful.", "Massive rallies are also planned in more than 100 US cities on Tuesday, as labor, immigration and Occupy activists are set to gather in support of the international workers' holiday.", "Historically, May 1st – International Workers' Day – came into being in memory of workers' demonstrations that took place in Chicago in May 1886. ", "May 1 is also recognized in the US as Law Day.", "\n\n­Russia: Maintaining long-held May Day traditions Russian Trade Unions and the ruling United Russia party have been the first to march in Moscow and according to police, 120,000 of their supporters have shown up in the city center. ", "Outgoing President Medvedev and President-elect Putin have joined the rally which makes the event unique. ", "Heads of state have previously never participated in mass rallies alongside other activists.", "Communists, liberals and nationalists have held separate marches. ", "All in all some 20 separate events have been announced ahead of the holiday.", "However massive the rallies were, everything ended peacefully, without any major violations.", "Similar events are taking place throughout the country. ", "Due to time differences, some rallies in Russia’s Far East, Siberia and Urals have already finished. ", "About 220,000 people took to the streets in the Far East. ", "The events in the Sakhalin Region, however, were canceled due to heavy rain. ", "Regions to the west of Moscow joined the holiday later on Tuesday." ]
{ "pile_set_name": "OpenWebText2" }
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0.001869
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[ "/*\n * DO NOT ALTER OR REMOVE COPYRIGHT NOTICES OR THIS HEADER.", "\n *\n * Copyright (c) 1997-2012 Oracle and/or its affiliates. ", "All rights reserved.", "\n *\n * The contents of this file are subject to the terms of either the GNU\n * General Public License Version 2 only (\"GPL\") or the Common Development\n * and Distribution License(\"CDDL\") (collectively, the \"License\"). ", " You\n * may not use this file except in compliance with the License. ", " You can\n * obtain a copy of the License at\n * https://glassfish.dev.java.net/public/CDDL+GPL_1_1.html\n * or packager/legal/LICENSE.txt. ", " See the License for the specific\n * language governing permissions and limitations under the License.", "\n *\n * When distributing the software, include this License Header Notice in each\n * file and include the License file at packager/legal/LICENSE.txt.", "\n *\n * GPL Classpath Exception:\n * Oracle designates this particular file as subject to the \"Classpath\"\n * exception as provided by Oracle in the GPL Version 2 section of the License\n * file that accompanied this code.", "\n *\n * Modifications:\n * If applicable, add the following below the License Header, with the fields\n * enclosed by brackets [] replaced by your own identifying information:\n * \"Portions Copyright [year] [name of copyright owner]\"\n *\n * Contributor(s):\n * If you wish your version of this file to be governed by only the CDDL or\n * only the GPL Version 2, indicate your decision by adding \"[Contributor]\n * elects to include this software in this distribution under the [CDDL or GPL\n * Version 2] license.\" ", " If you don't indicate a single choice of license, a\n * recipient has the option to distribute your version of this file under\n * either the CDDL, the GPL Version 2 or to extend the choice of license to\n * its licensees as provided above. ", " However, if you add GPL Version 2 code\n * and therefore, elected the GPL Version 2 license, then the option applies\n * only if the new code is made subject to such option by the copyright\n * holder.", "\n */\n// Portions Copyright [2018] Payara Foundation and/or affiliates\n\npackage com.sun.enterprise.config.serverbeans;\n\nimport com.sun.enterprise.config.serverbeans.customvalidators.", "ReferenceConstraint;\n\nimport java.beans.", "PropertyVetoException;\nimport java.util.", "List;\nimport javax.validation.constraints.", "NotNull;\nimport javax.validation.constraints.", "Pattern;\nimport javax.validation.", "Payload;\n\nimport org.jvnet.hk2.config.types.", "Property;\nimport org.jvnet.hk2.config.types.", "PropertyBag;\nimport org.glassfish.api.admin.config.", "Named;\nimport org.glassfish.grizzly.config.dom.", "Ssl;\nimport static org.glassfish.config.support.", "Constants.", "NAME_REGEX;\nimport org.glassfish.api.admin.config.", "PropertiesDesc;\nimport org.glassfish.quality.", "ToDo;\nimport org.jvnet.hk2.config.*;", "\n\n/**\n * The jmx-connector element defines the configuration of a JSR 160 compliant\n * remote JMX Connector. ", " \n */\n@Configured\n@ReferenceConstraint(skipDuringCreation=true, payload=JmxConnector.class)\npublic interface JmxConnector extends ConfigBeanProxy, Named, PropertyBag, Payload {\n final static String PORT_PATTERN = \"\\\\$\\\\{[\\\\p{L}\\\\p{N}_][\\\\p{L}\\\\p{N}\\\\-_./;#]*\\\\}\"\n + \"|[1-9]|[1-9][0-9]|[1-9][0-9][0-9]|[1-9][0-9][0-9][0-9]\"\n + \"|[1-5][0-9][0-9][0-9][0-9]|6[0-4][0-9][0-9][0-9]\"\n + \"|65[0-4][0-9][0-9]|655[0-2][0-9]|6553[0-5]\";\n \n /**\n * Gets the value of the enabled property.", "\n *\n * Defines if this connector is enabled. ", "For EE this must be enabled\n * \n * @return possible object is\n * {@link String }\n */\n @Attribute (defaultValue=\"true\", dataType=Boolean.class)\n String getEnabled();\n\n /**\n * Sets the value of the enabled property.", "\n *\n * @param value allowed object is {@link String }\n * @throws PropertyVetoException\n */\n void setEnabled(String value) throws PropertyVetoException;\n\n /**\n * Gets the value of the protocol property.", "\n *\n * Defines the protocol that this jmx-connector should support.", "\n * Supported protocols are defined by Entity rjmx-protocol. ", "\n * Other protocols can be used by user applications independently.", "\n * \n * @return possible object is\n * {@link String }\n */\n @Attribute (defaultValue=\"rmi_jrmp\")\n String getProtocol();\n\n /**\n * Sets the value of the protocol property.", "\n *\n * @param value allowed object is {@link String }\n * @throws PropertyVetoException\n */\n void setProtocol(String value) throws PropertyVetoException;\n\n /**\n * Gets the value of the address property.", "\n *\n * Specifies the IP address or host-name.", "\n * \n * @return possible object is\n * {@link String }\n */\n @Attribute\n @NotNull\n String getAddress();\n\n /**\n * Sets the value of the address property.", "\n *\n * @param value allowed object is {@link String }\n * @throws PropertyVetoException\n */\n void setAddress(String value) throws PropertyVetoException;\n\n /**\n * Gets the value of the port property.", "\n *\n * Specifies the port of the jmx-connector-server. ", "Note that jmx-service-url\n * is a function of protocol, port and address as defined by the JSR 160 1.0\n * Specification.", "\n * \n * @return possible object is {@link String }\n */\n @Attribute\n @Pattern(regexp=PORT_PATTERN,\n message=\"{port-pattern}\",\n payload=JmxConnector.class)\n String getPort();\n\n /**\n * Sets the value of the port property.", "\n *\n * @param value allowed object is {@link String }\n * @throws PropertyVetoException\n */\n void setPort(String value) throws PropertyVetoException;\n\n /**\n * Gets the value of the acceptAll property.", "\n *\n * Determines whether the connection can be made on all the network\n * interfaces. ", "A value of false implies that the connections only for this\n * specific address will be selected.", "\n * \n * @return possible object is {@link String }\n */\n @Attribute (defaultValue=\"false\", dataType=Boolean.class)\n String getAcceptAll();\n\n /**\n * Sets the value of the acceptAll property.", "\n *\n * @param value allowed object is {@link String }\n * @throws PropertyVetoException\n */\n void setAcceptAll(String value) throws PropertyVetoException;\n\n /**\n * Gets the value of the auth-realm-name property.", "\n *\n * The name of the auth-realm in this config element that represents the\n * special administrative realm. ", "All authentication (from administraive GUI\n * and CLI) will be handled by this realm.", "\n *\n * Note: This is deprecated since GlassFish v3 FCS. ", "Use similarly named attribute on admin-service. ", "This will\n * be used only when the admin-service attribute in missing.", "\n * @return String representing the name of auth realm\n */\n @Deprecated\n @Attribute\n @NotNull\n @Pattern(regexp=NAME_REGEX)\n @ReferenceConstraint.", "RemoteKey(message=\"{resourceref.invalid.auth-realm-name}\", type=AuthRealm.class)\n String getAuthRealmName();\n\n /**\n * Sets the value of the authRealmName property.", "\n *\n * @param value allowed object is {@link String }\n * @throws PropertyVetoException\n */\n void setAuthRealmName(String value) throws PropertyVetoException;\n\n /**\n * Gets the value of the securityEnabled property.", "\n *\n * Decides whether the transport layer security be used in jmx-connector.", "\n * If true, configure the ssl element\n * \n * @return possible object is {@link String }\n */\n @Attribute (defaultValue=\"true\", dataType=Boolean.class)\n String getSecurityEnabled();\n\n /**\n * Sets the value of the securityEnabled property.", "\n *\n * @param value allowed object is {@link String }\n * @throws java.beans.", "PropertyVetoException\n */\n void setSecurityEnabled(String value) throws PropertyVetoException;\n\n /**\n * Gets the value of the ssl property.", "\n *\n * @return possible object is {@link Ssl }\n */\n @Element\n Ssl getSsl();\n\n /**\n * Sets the value of the ssl property.", "\n *\n * @param value allowed object is {@link Ssl }\n * @throws PropertyVetoException\n */\n void setSsl(Ssl value) throws PropertyVetoException;\n \n /**\n * Properties as per {@link PropertyBag}\n * @return \n */\n @ToDo(priority=ToDo.", "Priority.", "IMPORTANT, details=\"Provide PropertyDesc for legal props\" )\n @PropertiesDesc(props={})\n @Element\n @Override\n List<Property> getProperty();\n}\n" ]
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[ " UNPUBLISHED\n\n UNITED STATES COURT OF APPEALS\n FOR THE FOURTH CIRCUIT\n\n\n No. ", "11-1004\n\n\nTHEODORE GRANGE,\n\n Plaintiff – Appellant,\n\n v.\n\nSOUTHEASTERN MECHANICAL SERVICES, INCORPORATED,\n\n Defendant – Appellee.", "\n\n\n\nAppeal from the United States District Court for the District of\nMaryland, at Baltimore. ", " J. Frederick Motz, Senior District\nJudge. (", "1:09-cv-02725-JFM)\n\n\nSubmitted: April 28, 2011 Decided: May 3, 2011\n\n\nBefore DAVIS, KEENAN, and WYNN, Circuit Judges.", "\n\n\nAffirmed by unpublished per curiam opinion.", "\n\n\nTheodore Grange, Appellant Pro Se. ", " Precious Murchison Gittens,\nGREENBERG TRAURIG, LLP, Washington, D.C.; David W. Long-Daniels,\nNatasha L. Wilson, GREENBERG TRAURIG LLP, Atlanta, Georgia; John\nFrancis Scalia, GREENBERG TRAURIG, LLP, McLean, Virginia, for\nAppellee.", "\n\n\nUnpublished opinions are not binding precedent in this circuit.", "\n\fPER CURIAM:\n\n Theodore Grange appeals the district court’s order\n\ngranting Southeastern Mechanical Services, Inc.’s motion for\n\nsummary judgment on Grange’s race discrimination claim, brought\n\npursuant to Title VII of the Civil Rights Act of 1964, as\n\namended, 42 U.S.C.A. §§ 2000e to 2000e-17 (West 2003 & Supp.", "\n\n2010). ", " Finding no reversible error, we affirm.", "\n\n We review de novo a district court’s grant of summary\n\njudgment. ", " Howard v. Winter, 446 F.3d 559, 565 (4th Cir. ", "2006).", "\n\nSummary judgment is appropriate when the “pleadings,\n\ndepositions, answers to interrogatories, and admissions on file,\n\ntogether with the affidavits, if any, show that there is no\n\ngenuine issue as to any material fact and the moving party is\n\nentitled to summary judgment as a matter of law.” ", " Fed. ", "R. Civ.", "\n\nP. 56(c).", "\n\n To establish his discrimination claim, Grange was\n\nfirst required to establish a prima facie case of discrimination\n\nunder the burden-shifting framework adopted by the Supreme Court\n\nin McDonnell Douglas Corp. v. Green, 411 U.S. 792, 802 (1973).", "\n\nThus, Grange was required to show that (1) he belongs to a\n\nprotected class; (2) he applied and was qualified for a job for\n\nwhich Southeastern Mechanical was seeking applicants;\n\n(3) despite his qualification, he was rejected; and (4) after\n\n\n\n 2\n\fhis rejection, the position remained open and the employer\n\ncontinued to seek applicants.", "\n\n We hold that Grange failed to establish a prima facie\n\ncase of discrimination and, therefore, we need not proceed under\n\nthe McDonnell Douglas framework. ", " Grange could not show that he\n\nwas qualified and rejected despite his qualifications. ", " In fact,\n\nthe evidence showed that Southeastern Mechanical Services did\n\nnot hire Grange as a welder because he failed his pre-employment\n\nwelding test.", "\n\n Accordingly, we affirm the district court’s judgment.", "\n\nConsequently, we deny Grange’s motion to appoint counsel. ", " We\n\ndispense with oral argument because the facts and legal\n\ncontentions are adequately presented in the materials before the\n\ncourt and argument would not aid the decisional process.", "\n\n\n\n AFFIRMED\n\n\n\n\n 3\n\f" ]
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[ "---\nabstract: |\n In this paper we demonstrate the use of multivariate topological algorithms to analyse and interpret Lattice Quantum Chromodynamics (QCD) data. ", "Lattice QCD is a long established field of theoretical physics research in the pursuit of understanding the strong nuclear force. ", "Complex computer simulations model interactions between quarks and gluons to test theories regarding the behaviour of matter in a range of extreme environments. ", "Data sets are typically generated using Monte Carlo methods, providing an ensemble of configurations, from which observable averages must be computed. ", "This presents issues with regard to visualisation and analysis of the data as a typical ensemble study can generate hundreds or thousands of unique configurations.", "\n\n We show how multivariate topological methods, such as the Joint Contour Net, can assist physicists in the detection and tracking of important features within their data in a temporal setting. ", "This enables them to focus upon the structure and distribution of the core observables by identifying them within the surrounding data. ", "These techniques also demonstrate how quantitative approaches can help understand the lifetime of objects in a dynamic system.", "\naddress:\n- 'Department of Computer Science, Swansea University, Swansea, United Kingdom'\n- 'Department of Physics, Swansea University, Swansea, United Kingdom'\n- 'Department of Informatics, Kings College London, London, United Kingdom'\nauthor:\n- 'Dean P.Thomas'\n- Rita Borgo\n- 'Robert S.Laramee'\n- 'Simon J.Hands'\nbibliography:\n- 'references.bib'\ntitle: Joint Contour Net Analysis for Feature Detection in Lattice Quantum Chromodynamics Data\n---\n\nmultivariate,topology driven visualisation,temporal data,analysis,volume visualisation,lattice quantum chromodynamics\n" ]
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[ "If you don’t love Whataburger, you’re probably not a Texan. ", "Here are the 12 big reasons that we love it.", "\n\n12. ", "It’s Impossible To Turn Down When Someone Offers It\n\nVia Dr\n\nIt doesn’t matter when someone asks. ", "It’s literally impossible to turn down, especially if someone is offering to pick it up for you.", "\n\n11. ", "It’s Like A Church Where The Religion Is Deliciousness\n\nEvery Whataburger restaurant is a sanctuary of satisfying foods. ", "As a child, they bring joy. ", "As an adult, they bring sustenance. ", "As a human, they bring us together. ", "Whataburger can’t save us like Jesus, but it can magically heal a hungry stomach.", "\n\n10. ", "Nothing Gets Us Amped Like Finding Out We’re About To Eat Whataburger\n\nMost people who need to get amped up listen to their favorite song, or maybe take a 5-hour energy. ", "A true Whataburger fan doesn’t need any of that. ", "A true Whataburger fan needs a meal from their favorite orange and white restaurant. ", "Maybe a giant sweet tea. ", "Heck, throw in some Spicy Ketchup and you’ve got a party.", "\n\n9. ", "We All Wish The Whataburger Guy Was Our Grandpa\n\nSeriously though. ", "That guy’s voice was awesome. ", "Sadly, he was retired from the brand recently, but his memory still lives on in our hearts and stomaches.", "\n\n8. ", "There Are 36,864 Ways To Customize A Whataburger\n\nTexans believe in freedom; freedom to enjoy our food just like we like it. ", "That’s why Whataburger was created. ", "It was created to help facilitate the celebration of food freedom. ", "Do your part in fighting terrorism and promoting freedom. ", "Order a Whataburger, just like you like it.", "\n\n7. ", "The Whataburger Sign Is Like An Oasis In A Desert Of Terrible Fast Food\n\nThe highways in this state are as long as they are…well, long. ", "On a long trip somewhere, our hunger can get really intense and when you only pass Arby’s and Long John Silver on the highway, nothin’ looks tastier than a massive Whataburger sign on the horizon. ", "The Orange and White “W” sign is like a massive hand beckoning you to pull over and take a few minutes to enjoy a delicious meal as a reward for surviving the miles and miles of Texas." ]
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[ "Ready to fight back? ", "Sign up for Take Action Now and get three actions in your inbox every week. ", "You will receive occasional promotional offers for programs that support The Nation’s journalism. ", "You can read our Privacy Policy here. ", "Sign up for Take Action Now and get three actions in your inbox every week.", "\n\nThank you for signing up. ", "For more from The Nation, check out our latest issue\n\nSubscribe now for as little as $2 a month!", "\n\nSupport Progressive Journalism The Nation is reader supported: Chip in $10 or more to help us continue to write about the issues that matter. ", "The Nation is reader supported: Chip in $10 or more to help us continue to write about the issues that matter.", "\n\nFight Back! ", "Sign up for Take Action Now and we’ll send you three meaningful actions you can take each week. ", "You will receive occasional promotional offers for programs that support The Nation’s journalism. ", "You can read our Privacy Policy here. ", "Sign up for Take Action Now and we’ll send you three meaningful actions you can take each week.", "\n\nThank you for signing up. ", "For more from The Nation, check out our latest issue\n\nTravel With The Nation Be the first to hear about Nation Travels destinations, and explore the world with kindred spirits. ", "Be the first to hear about Nation Travels destinations, and explore the world with kindred spirits.", "\n\nSign up for our Wine Club today. ", "Did you know you can support The Nation by drinking wine?", "\n\n\n\nThe president's budget proposal includes the expected Chained-CPI cut. (", "AP Photo/Manuel Balce Ceneta). ", "Ad Policy\n\nPresident Obama released his proposed 2014 budget Wednesday morning, and it included a hugely controversial provision: a switch to a Chained-CPI formula for calculating inflation.", "\n\nMany different government programs—most notably Social Security—calculate benefits based on the rate of inflation, so that benefits don’t lag behind an increased cost of living. ", "The IRS uses similar formulas to ensure that people aren’t pushed into a higher bracket simply because of inflation.", "\n\nAs Dylan Matthews explains here, the government uses several different formulas to do this, and the administration is proposing to unify them all into one formula, called Chained-CPI-U. It purports to be a more accurate measure of inflation by controlling for “substitution effects.”", "\n\nCurrent formulas might, for example, rate an increase in the price of beef as inflation, but not consider the fact that people might start buying chicken instead. ", "Chained CPI aims to control for the choices people make in the face of rising prices, and so the inflation it calculates naturally rises more slowly.", "\n\nGenerally this means fewer benefits would be paid out, and people would be pushed into higher tax brackets more quickly—and both result in more money for the government, and thus more deficit reduction. ", "The White House estimates this approach would save $230 billion over ten years.", "\n\nSeems sensible: but there are a lot of hidden dangers, both on policy and politics, and the White House and its defenders aren’t always forthright about them. ", "Here are the top five myths about Chained-CPI.", "\n\n1) It’s not a benefit cut, nor a tax increase\n\nA recent briefing paper from the Bowles-Simpson “Moment of Truth” group (citing the economist Robert Greenstein) asserts “this change should not be regarded as a benefit cut or a tax increase. ", "It should be regarded more as a technical change to achieve Congress’s stated goal of keeping pace with inflation in as accurate a way as possible.”", "\n\nSimilarly, the White House shies away from calling this a benefit cut: in Obama’s budget, for example, it’s depicted as a “more accurate” formula that “will reduce deficits and improve Social Security solvency.”", "\n\nWe’ll get to the accuracy argument next, but there’s no debating these simple points: Chained-CPI is both a benefit cut and a tax increase.", "\n\nThe average earner retiring at age 65 would lose $658 each year until they turned 75 under Chained-CPI, and a $1,147 cut by 85. ", "This really adds up—the cumulative cuts to people on Social Security reach $28,000 by the time a retiree is 95, as this chart from Social Security Works shows:\n\nBowles-Simpson has what’s called a “birthday bump” in their Chained-CPI formula: an increase in benefits in the 20th year to help offset the cuts, something the White House endorses. ", "But this still fails to make up for the benefit cuts. ", "Here’s Social Security Works again:\n\nChained CPI also has the effect of raising taxes by pushing people to higher marginal rates. ", "It’s not a huge effect, but one that’s quite regressive: middle-income earners are hit the hardest. ", "Here’s a chart from Dylan Matthews:\n\nMatthews notes that “[t]he group getting the biggest tax hike is families making between $30,000 and $40,000 a year. ", "Their increase is almost six times that faced by millionaires.”", "\n\n2) It’s a more accurate measure of inflation\n\nProponents of Chained-CPI rebut the benefit cuts by making an accuracy argument—suggesting that beneficiaries are getting an unfair windfall from current inflation formulas that are over-compensating for inflation.", "\n\nThere’s no doubt that, economy-wide, Chained-CPI is a more accurate measure of growth in living standards. ", "But that just doesn’t hold when applied to seniors on Social Security.", "\n\nThe argument for Chained-CPI is that average consumers replace items in their “basket” of goods when something gets too expensive. ", "But seniors have quite a different basket of goods—namely, a lot of out-of-pocket spending on health care, which outpaces inflation and is also extremely hard to replace. (", "In fact, even the current formula for calculating Social Security benefits probably understates the real cost of living for seniors.)", "\n\nThe Economic Policy Institute has the numbers here:\n\nIn short, the 65-and-older households spend roughly three times what the rest of the population does on health care, measured as a share of total spending. ", "Further, between 1989 and 2007,prices for health care have risen nearly twice as fast as overall inflation—growing 100% over that timespan, compared with 53% growth in overall prices of consumption goods.", "\n\nSeniors spend a lot of money on health care, and just aren’t able to buy different, cheaper drugs when the price of their medication goes up—so the Chained CPI argument just doesn’t work here. ", "And the price of those drugs is going up much faster than the prices of most consumer goods, and the same is true of Medicare premiums.", "\n\nEPI concludes that “In short, rising health care costs and falling incomes already provide large pressures on Social Security beneficiaries’ incomes as they age. ", "Reducing the [cost-of-living] adjustment would just apply one more economic pressure that grows over their retirement.” ", "They advocate switching not to Chained-CPI-U, but CPI-E, which measures cost-of-living increases among the senior population.", "\n\nNote, too, that these seniors are the ones bearing most of the brunt from switching to Chained-CPI government-wide: about $115 billion of the $230 billion in estimated savings comes from Social Security.", "\n\n3) We can enact Chained-CPI still protect veterans and the most vulnerable\n\nThe White House says that it will insist on protections for the most vulnerable and for veterans under any Chained-CPI plan. (", "This is, by the way, already a tacit admission that Chained-CPI isn’t truly more accurate—if it was, and all it was doing was removing an unnecessary windfall to beneficiaries, why does anyone need protection?)", "\n\nThe administration proposes the aforementioned “birthday bump,” which as we noted still doesn’t make up for the benefit cut. ", "They also advocate protecting lowest-income seniors and people with disabilities by exempting Supplemental Security Income from Chained-CPI.", "\n\nBut here’s the problem: SSI is already too small, and doesn’t reach enough poverty-stricken seniors. ", "In fact, there are 9.4 million poor or near-poor people who receive Social Security, but not SSI—so they still get hit. ", "In addition, there are 2.8 million “dual-eligibles”—people who are on SSI but also receive some Social Security benefits. ", "They’d be hit as well.", "\n\nWhile the administration laudably wants to protect various veteran’s benefits programs from Chained-CPI, 9.3 million veterans are on Social Security, which is one in five Social Security beneficiaries. ", "So they still won’t be totally insulated from the Chained-CPI cuts either.", "\n\n4) It will help achieve a deal with the GOP\n\nObama argues that Chained-CPI isn’t what he wants, but what he feels he must to do get a deal with the GOP. “", "I don’t believe that all these ideas are optimal, but I’m willing to accept them as part of a compromise,” Obama said in the Rose Garden Wednesday.", "\n\nBut he proposed Chained-CPI during the debt-ceiling talks in 2011, and the GOP did not accept his grand bargain. ", "He proposed them as part of a deal to avert the sequester earlier this year, and the GOP did not accept the deal. ", "Now he’s proposing them in his budget. ", "Is the result any different?", "\n\nWell, no. ", "Paul Ryan rejected the idea that Chained-CPI would make a deal with Obama viable. “", "I don’t see this as fundamental entitlement reform as much as clarifying a statistic which does happen to save money,” he said Wednesday.", "\n\nNo Republicans in the House or Senate have yet said they were interested in Obama’s budget, and the prospect of them doing so is non-existent.", "\n\nIn fact, Obama may be unintentionally strengthening the Republican’s hand in this debate by validating their theory of deficit reduction.", "\n\nThe Obama approach during the 2012 campaign was that the deficit should be addressed by a sensible mix of spending cuts and new revenue, and that the safety net should be protected. ", "These Democratic Party priorities were reflected in the Senate Democrats’ budget, which did not contain Chained-CPI. ", "The Republican approach, meanwhile, is that deficit reduction should consist of cuts and cuts only, and “serious entitlement reform.”", "\n\nInstead of battling the GOP on the idea that cutting the safety net is a bad way to reduce deficits—particularly Social Security, which doesn’t even contribute to it—Obama has endorsed the GOP approach by agreeing to Chained CPI. ", "And don’t think they won’t point that out—and use it to advance the ball on cutting entitlements.", "\n\nHere’s Mitch McConnell Wednesday, after the Obama budget was released:\n\n“The President seems prepared to finally concede this time that at least something needs to be done to save entitlements from their inevitable slide toward bankruptcy. ", "I’m glad to see him begin to come to grips with the math here. ", "It’s well past time for reform, and it’s something the President ought to want to do because he presumably cares about saving entitlement programs – not just because he wants yet another excuse to raise taxes.”", "\n\nHere’s House Speaker John Boehner:\n\n“[Obama] does deserve some credit for some incremental entitlement reforms that he has outlined in his budget. ", "But I would hope that he would not hold hostage these modest reforms for his demand for bigger tax hikes. ", "Listen, why don’t we do what we can agree to do? ", "Why don’t we find the common ground that we do have and move on that?”", "\n\nThink of this phase of the sequestration and budget fight as an election—where each side tries to convince the public that their approach is optimal. ", "Winning means the other side is under the gun of public opinion and comes to the table ready to deal.", "\n\nEndorsing the other side’s ideas during this phase is not terrific strategy. ", "Might Obama have to accept some Republican ideas in the final agreement? ", "Sure, but the GOP has shown absolutely zero desire to reach an agreement, so prematurely endorsing their approach is explicitly counter-productive.", "\n\nDefenders of the White House strategy theorize this approach is helpful for public opinion because it highlights that the GOP is unwilling to compromise.", "\n\nBut what’s the added value of highlighting what virtually everybody in the country who follows this debate understands? ", "As Matthew Yglesias writes: “To any reasonable person, the fact that the GOP ran in 2008 and 2010 and 2012 on a platform of all-cuts deficit reduction makes that clear. ", "If you need further evidence you can look at the GOP's negotiating strategy during the 2011 debt ceiling battle, during the fiscal cliff in the 2012 lame duck session, and all throughout the sequestration controversy. ", "You can ask John Boehner. ", "Or Eric Cantor. ", "Or Mitch McConnell. ", "There's a lot that's murky in American politics, but it's incredibly clear that the reason we don't have a grand bargain on the budget is that Republicans don't want one.”", "\n\n5) It won’t hurt Democrats in 2014\n\nA key argument against Chained-CPI that progressives have made for months is that Republicans would use it to slam Democrats in the 2014 midterms, just as they did with the Medicare cuts in Obamacare.", "\n\nAnd just on cue, the head of the House GOP re-election committee appeared on CNN yesterday and said that Obama’s budget “lays out a shocking attack on seniors.” ", "He continued:\n\n“I’ll tell you when you’re going after seniors the way he’s already done on Obamacare, taken $700 billion out of Medicare to put into Obamacare and now coming back at seniors again, I think you’re crossing that line very quickly here in terms of denying access to seniors for health care in districts like mine certainly and around the country.”", "\n\nThe White House pushback is twofold. ", "First, point out this isn’t what Obama really wants. “", "This is a Republican proposal,” White House press secretary Jay Carney said on Thursday. ", "Actually, it’s in Obama’s budget, so good luck with that defense.", "\n\nMeanwhile, senior White House officials ultimately think this line of attack won’t be effective in 2014. “", "The White House…feels it can win any political fight on entitlements…after the successful test case of the 2012 campaign, when Republicans tried to make an issue of the $700 billion in Medicare savings contained in Obamacare, but didn’t land any body blows,” Alex Seitz-Wald reported after a briefing from administration officials.", "\n\nThat’s wrong for a couple reasons. ", "For one, the $700 billion in Medicare cuts were largely sensible and did not depress the Democratic base nor divide the party, as the push to cut Social Security will. (", "Every major progressive group has blasted Obama’s Chained-CPI approach, gathered petitions, and even threatened to primary Democrats who vote for it.)", "\n\nTwo, one can’t take an extremely reductive approach to the 2012 election: just because Obama won, every attack Romney and Ryan wasn't per se ineffective. ", "The ferocity and frequency with which they attacked the $700 billion in cuts suggests they had data showing it was costing Obama votes. ", "Just because it didn’t cost him enough votes doesn’t mean it’s a bad strategy.", "\n\nMoreover, polls show that Chained CPI is horribly unpopular:\n\nThe AARP reveals that 70 percent of voters age 50-plus oppose the use of the chained CPI to cut benefits, and two-thirds of them – including 60 percent of Republicans — say they would be “considerably less likely” to support a congressional candidate if he or she backed a new way of calculating consumer prices. ", "And 84 percent of voters over 50 say Social Security has no place in budget-deficit discussions, since it is self-financed.", "\n\nYou can’t just brush that off by saying “Obama won in 2012.”", "\n\nGeorge Zornick last wrote about another new proposal in Washington that has left much of the country disappointed: the gun control package." ]
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[ "The present invention relates to the production of electrically conductive polypyrrole, and is particularly concerned with a novel chemical process for applying a conductive polypyrrole layer or film on a suitable substrate, for production of conductive composites or structural materials.", "\nPolypyrrole represents one of the most environmentally stable conducting organic polymers. ", "Its usual preparation has involved electrochemical oxidation of pyrroles in various solvents, with films of the conducting materials depositing on the anode. ", "Thus, free-standing polypyrrole films from about 10 .mu.m to 20 mil thick have been produced on electrodes by electrochemical polymerization. ", "However, these prior art films are too thin and too brittle to be useful in most structurally related applications.", "\nU.S. Pat. ", "No. ", "4,552,927 to L. F. Warren discloses a conductive polypyrrole which can be produced in thicker layers and has increased mechanical flexibility as compared to prior art polypyrrole film, obtained by electropolymerizing pyrrole from an electrolyte containing a non-nucleophilic polymeric anion, such as polystyrenesulfonate, and pyrrole.", "\nU.S. Pat. ", "No. ", "4,582,575 to L. F. Warren, D. S. Klivans and L. Maus, discloses an electrically conductive composite comprising a dielectric porous substance, such as fiberglass fabric, and an electrically conductive pyrrole polymer deposited in the pores of such substance, by contacting such porous substance with an anode in an electrolytic cell containing an electrolyte comprising a pyrrole monomer and a substantially non-nucleophilic anion, such as sulfate, and electrochemically depositing a conductive pyrrole polymer in the pores of such substance.", "\nU.S. application Ser. ", "No. ", "646,717, filed Sept. 4, 1984, of P. R. Newman, L. F. Warren, Jr. and E. F. Witucki, now U.S. Pat. ", "No. ", "4,617,228 and assigned to the same assignee as the present application, discloses a chemical process for producing an electrically conductive composite which comprises contacting a dielectric porous substance, such as fiberglass fabric with a liquid pyrrole, then contacting the porous substance with a solution of a strong oxidant capable of oxidizing pyrrole to a pyrrole polymer, such as ferric cation, and oxidizing the pyrrole in the presence of a substantially non-nucleophilic anion, such as sulfate, and precipitating a conductive pyrrole polymer in the pores of such substance.", "\nAn object of the present invention is the provision of a novel process for applying a conductive polypyrrole to a substrate to produce electrically conductive composites or structural materials.", "\nAnother object of the invention is to provide procedure for applying a conductive polypyrrole layer or film to a dielectric structural material to produce an electrically conductive composite." ]
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0.012007
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[ "Developing Games for Android\n\nBy Derek James\n\nThe advent of smartphones has opened up an entire new range of platforms for game development, particularly for independent game developers. ", "The iPhone's App Store model has been enormously successful, with a recent estimate of $2.4 billion in annual sales.", "\n\nFrom a developer's perspective, app stores have the incentive of a distribution channel with powerful search and marketing capabilities. ", "They also provide an intermediary that handles the logistics of selling and downloading -- generally for a cut of 30%.", "\n\nYou've probably heard the Cinderella stories of developers like Steve Demeter, whose triangular variant on match-3 games, Trism, reportedly earned him $250,000 in just two months in the iPhone App Store. ", "Take also Ethan Nicholas' iShoot, which reportedly earned $600,000 in a single month. ", "With the gold rush mentality and the iPhone's undeniable success with the App Store, why would a game developer choose to make a game for any other smartphone platform?", "\n\nAbout six months ago, I started developing games for Google's Android OS, somewhat by chance. ", "A friend who works for Google gave me a G1 developer's phone as a gift. ", "At that point, I hadn't even heard of Android. ", "In the process of learning about the OS, I came across the Android SDK, and downloaded it to give it a spin. ", "I was instantly hooked.", "\n\nWhile iPhone apps are written in Objective C, the Android SDK uses relatively more programmer-friendly Java. ", "The iPhone store charges developers $99 a year to distribute their apps, while Android has a one-time $25 fee for developers. ", "And the review process for iPhone apps grows increasingly lengthy -- sometimes weeks or more -- and it's somewhat arcane. ", "Android apps go live as soon as the developer hits the publish button. ", "Google handles the review process post-hoc, and is much more lax in terms of content.", "\n\nWith the greater ease of producing and distributing apps through the Android Market, why aren't game developers large and small clambering to produce quality games for the system? ", "There are a number of reasons, but number one is, of course, money.", "\n\nMobile ad company AdMob released its July 2009 report (pdf) which notes the following:\n\n45 million estimated combined iPhone and iPod Touch users, compared to 3 million Android users\n\n50% of iPhone users bought at least one paid app during a month period, compared to 19% of Android users\n\nThe estimated market value of the iPhone App Store is about $200M per month, compared to an estimate of about $5M per month for the Android Market\n\nSo a major part of the equation is pure size. ", "But another factor is the population makeup of Android users and their perception of the platform. ", "The iPhone user population is likely much more diverse, with a greater cross-section of users representing more diverse demographics, while the Android user population is still likely predominantly tech-centric early adopters. ", "Since Android is an open-source system, the perception may also be that the software that runs it should follow the same model. ", "Thus many users may be reticent to spend money on apps.", "\n\nOf course, the hope among Android game developers is that an influx of new phones on a variety of new carriers will increase and diversify the user base, increasing sales. ", "However, current reports are gloomy. ", "One case study is Larva Labs, a New York based mobile game developer. ", "Larva recently shared its sales stats for August, and they weren't pretty. ", "Despite having two games in the market that both spent time in the top 10 among paid apps in their categories, the daily average income for August was $62.39.", "\n\nThe developer laments issues with the market interface (poor organization and search) and a lax return policy (24-48 hour returns, no questions asked). ", "But the issue of piracy is also raised, and is another likely source of poor performance of games in the Android Market. ", "A cursory search of popular torrent sites reveals bundles of Android games for download.", "\n\nThe next release of Android is bringing much needed revisions to the market interface. ", "As for piracy, as with any game market, it is difficult to determine the impact. ", "The Android Market includes optional DRM, but it is unlikely to slow or deter would-be pirates.", "\n\nUnlike the iPhone, an Android device does not need to be jailbroken in order to allow installation of pirated apps. ", "A user can simply install pirated apps onto their SD card and use one of the freely-available app installers from the market. ", "The return policy even allows a would-be pirate to download an app, make a copy, and then get a full refund. ", "They don't even have to pay for the original copy they pirate!", "\n\nOne viable way to mitigate the effects of piracy is to monetize apps through advertising, rather than relying on direct sales. ", "About half of the revenue from my games has come from ads as opposed to direct sales.", "\n\nDespite the seemingly poor state of the Android market, the Larva Labs developers remain upbeat about the potential. ", "The mobile analytics company Flurry notes the growth of new Android projects next to the relative decline of new iPhone ones. ", "The AdMob market report mentioned earlier also notes that ad requests from Android have now edged out requests from Windows Mobile, both internationally and domestically. ", "While iPhone is still the king of the hill, Android is pushing its way into the market.", "\n\nThere are currently only two handsets that run Android available in the U.S.: the T-Mobile G1 (aka HTC Dream) and the T-Mobile myTouch (aka HTC Magic). ", "The G1 has a hardware keyboard, while the myTouch does not. ", "Other than that, both devices have the same screen size, and so far cross-device development is still pretty straightforward. ", "I've heard that both HTC and T-Mobile are pleased with the sales performance of both devices, though I'm not aware of hard figures. ", "Based on analytics from my own apps, about 20% of my existing user base own the myTouch.", "\n\nThe good news: a spate of new devices are on the way. ", "Motorola just unveiled its Android-powered Cliq, which will soon be available through T-Mobile. ", "Another Motorola phone announcement is expected soon. ", "Earlier this year, the estimate was that 18-20 Android-powered devices would be released by the end of the year. ", "That remains to be seen, but there it is extremely likely that by the holiday season there will be at least half a dozen Android smartphones, probably on multiple carriers.", "\n\nThings could get very interesting with this new wave of devices. ", "The myTouch alone hasn't changed the game, but the incremental influx of new hardware, especially with the openness and customizability of Android, and choice of carrier, could start to see Android carving out a significant portion of the market.", "\n\nOn the one hand, that seems like good news to Android developers. ", "An increase in the market can only be good, right? ", "Well, an open issue is one of device compatibility. ", "The current HTC devices have a trackball, while other devices may or may not, opting for a touchpad or alternative input device. ", "Another issue is screen resolution. ", "The current devices all have a 3.2 inch screen with a resolution of 480x320, but newer devices may have resolutions that are smaller or larger (e.g. there are already tablet PCs running Android slated for release).", "\n\nIn terms of RAM and processing power, there are not significant differences in the devices rolled out thus far. ", "Although continued improvements and custom builds of Android can get the most out of existing specs, the newer generation of Android smartphones -- those poised to be released by the end of this year -- should have more RAM and more powerful chipsets. ", "So building more CPU-intensive games for the platform will only get easier, but the decision to do so may become more difficult.", "\n\nOne advantage of programming for the iPhone is not having to worry (much) about hardware compatibility. ", "This could potentially be a problem for Android game developers as new handsets emerge. ", "The possibility of a backlash exists if users buy a new Android smartphone only to find that the most popular games in the market don't render properly on their screen, or that the control scheme for the game doesn't work. ", "A developer can try to work their way around these issues by designing for multiple screen resolutions and including multiple input methods, but this of course means extra work.", "\n\nOther issues include the limitations of the first-generation hardware that's currently running Android. ", "Specifically, battery life and storage space are both big issues on the G1, and games can tend to hog both, especially the more features they use. ", "I just finished a game for the second iteration of the Android Developers Challenge -- more on that in a moment -- and it uses the GPS functionality of the device. ", "Unfortunately, the GPS finder is a huge drain on the battery.", "\n\nAs for storage space, the G1 only has 70MB of storage allocated for apps. ", "That means designing lean games in terms of music and art assets, since users may not want to delete a bunch of existing apps to make way for your 10MB masterpiece. ", "The newer generation devices have several times the capacity, so in a sense these problems are being resolved as new hardware rolls off the shelves. ", "But the limitations are in place for most of the current generation of users and developers.", "\n\nLikely because Google is behind the curve in the smartphone game, it has instituted a strategy designed to lure developers to the platform with the promise of cash -- not in the form of market profit, but in prize money. ", "Last year Google held an open contest for the best apps, the Android Developer Challenge, a free-for-all in which candidate apps were selected by a panel of judges.", "\n\nThis year, it kicked off the Android Developer Challenge II, with $2M in prizes. ", "Rather than lumping all entries into one bin, ADC II is divided into 10 categories, including two for games (Casual/Puzzle and Arcade/Action). ", "The deadline for submissions closed on August 31st, and winners are to be decided by two rounds of judging: one by users and one by a panel of judges.", "\n\nHowever, If you hadn't heard of the challenge, you're probably not alone. ", "Google didn't do much to spread the word, probably assuming that the lure of large cash prizes would carry the news effectively. ", "With the overall winner set to take home $250,000, the strategy seems sound. ", "But the jury is out on whether or not the ADC II has been effective in drawing game developers to the platform. ", "The first contest had about 1,700 entrants, but no numbers on the second challenge have been released as of this writing.", "\n\nI spent the summer working on an entrant into the ADC II, a puzzle/RPG hybrid along the lines of Puzzle Quest, with the twist that the player must physically visit locations near them, such as coffee shops and grocery stores, in order to unlock content.", "\n\nDeveloping the game presented some unique challenges, learning how to incorporate the Google Map API, for example. ", "And some aspects of development still need a lot of work. ", "For example, the functionality for playing sounds and music is extremely limited and has been historically buggy. ", "However, overall the experience was very rewarding, and grassroots developer communities provided answers to nearly every issue I encountered. ", "In particular, the sites anddev.org and the Android Developers Google Group have been helpful.", "\n\nStill, there are existing issues that are problematic for the platform. ", "There are quite a few games for the iPhone that utilize an underlying physics engine, but I'm currently not aware of any games for Android that are physics-based. ", "Ports of some existing 2D engines to Android have apparently not performed well enough to use them for games. ", "Again, as with the other issues related to developing on first-generation hardware, newer devices will probably render them obsolete.", "\n\nFor now, if a developer decides to implement a game exclusively for a particular smartphone platform, and the choice is between the iPhone and Android, the tradeoff is between trying to get noticed in an incredibly crowded and competitive market where the potential payoff is huge for those at the top, or entering a market with low barriers, little competition, currently low returns, but the possibility of potential growth. ", "Hopefully there will continue to be developers that take both roads, and the smartphone market will continue to grow as a diverse outlet for game development.", "\n\nReturn to the full version of this article\n\nCopyright © UBM Tech, All rights reserved" ]
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0.005983
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[ "Q:\n\nHow to Convert String into Integer using Vuejs, vuex?", "\n\nI have a Little Problem with my application.", "\nI am currently making a Basic stock Trader app (as an exercise). ", "I am using Vuejs and Vuex. ", "\nIn my store.js file I am storing all the global variables but there is this problem with the bmw_quantity data.", "\nIt is mapped to a v-model (Input field) which you can see in the stocks.vue component. ", "For some reasons the data is always a string. ", "I don't know why and I also tried several things but I couldn't convert the things I type in the field into an actual integer and not a string.", "\nHere is my code: \n\nA:\n\nYou can use the .number modifier: https://vuejs.org/v2/guide/forms.html#number\n<input v-model.number=\"bmw_quantity\" type=\"number\">\n\n" ]
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0.014991
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[ "[Multiple intracranial tuberculomas in infancy].", "\nTuberculous involvement of the CNS is most frequent in children aged between 6 months and 6 years, although it may occur at any age. ", "It may present as meningoencephalitis, basal arachnoiditis or intracranial tuberculomas. ", "Whilst meningitis is typical of infancy, tuberculomas and arachnoiditis are commoner in adults. ", "It has been estimated that tuberculomas make up 3% of the cases of neurotuberculosis. ", "The increasing use of CAT and MR has been a great help for diagnosis of this serious complication of tuberculosis. ", "A 5 month old patient presented with tuberculous meningitis which had been treated with streptomycin, isoniazid, pyrazinamide and rifampicin at the usual dosage. ", "One month later, after good initial progress, triventricular hydrocephaly was diagnosed and a ventriculoperitoneal shunt inserted. ", "Three months after this, there was an episode of intracranial hypertension. ", "Cranial CAT showed considerable zones of hypodense parenchyma without ventricle dilatation. ", "On MR there were multiple, disseminated, rounded areas which were hyperintense on T2 and compatible with intracranial tuberculomas. ", "After fresh insertion of a ventricular shunt, the patient progressed but still had a residual right hemiparesia and retarded development. ", "Although intracranial tuberculomas usually occur in adults, they may be seen in children following meningoencephalitis. ", "Occasionally, following a good initial response to tuberculostatic drugs, tuberculomas appear, although not present before, as happened in our patient. ", "This usually occurs within the first three months, and although the mechanism is unknown, it is believed to be due to the accumulation of lymphocytes and macrophages at preexisting microscopic foci when treatment is started." ]
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0.002551
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[ "ISIL claims two 'soldiers' killed French priest after seizing hostages\n\nPolice have shot dead two men who took a priest and several others hostage at knifepoint at a church in north-western France.", "\n\nFrench President Francois Hollande stands outside the Saint-Etienne-du-Rouvray's city hall after holding a press conference following a hostage-taking at a church of the town that left the priest dead. ", "Hollande said that the attackers had \"claimed to be from Daesh,\" using the Arabic name for the Islamic State group.(Photo: CHARLY TRIBALLEAU, AFP/Getty Images)\n\nPARIS — France became the target of a new terrorist attack Tuesday, when two men armed with knives killed an elderly priest and injured three others after seizing hostages at a Catholic church in Normandy. ", "The Islamic State claimed responsibility.", "\n\nBoth attackers were shot dead by French police as they attempted to leave the church. ", "Three people were rescued unharmed, according to the French government. ", "Police said the two attackers recorded their actions inside the church, the French newspaper Le Figaro reported.", "\n\nThe incident took place around 9:30 during morning Mass at a parish church in Saint-Étienne-du-Rouvray, a community of 29,000 people near the city of Rouen, about 75 miles northwest of Paris.", "\n\nThe Amaq news agency, linked to Islamic State, said \"two IS soldiers\" carried out the hostage-taking. \"", "The two executors of the attack on a church in Normandy, France, were soldiers of the Islamic State,\" the news agency quoted the Islamic State. \"", "They executed the operation in response to calls to target countries belonging to the crusader coalition.\"", "\n\nThe slain priest was Jacques Hamel, 85, Archbishop of Rouen Dominique Lebrun said in a statement. ", "Police said it appeared the attackers had slit the priest's throat with a knife.", "\n\n“We are facing a group that has declared war on us,\" French President François Hollande said after rushing to Saint-Étienne-du-Rouvray. “", "We have to fight this war with every means.”", "\n\nThe latest attack came 12 days after 84 people were killed on Bastille Day (July 14) in Nice by a lone terrorist, possibly inspired by the Islamic State, who drove a large truck through the crowd. ", "France has been under a state of emergency since last November's terror attacks in Paris that killed 130 people.", "\n\nMolins said Kermiche was wearing an electronic surveillance bracelet that was deactivated for a few hours every morning, the Associated Press reported.", "\n\nKermiche, who grew up Saint-Étienne-du-Rouvray, was arrested in Germany in March 2015 trying to join extremists in Syria using his brother’s ID, and then was arrested in Turkey two months later using a cousin’s ID, Molins said. ", "Upon his return, he was put under judicial supervision with an electronic bracelet, the AP said.", "\n\nA nun who was in the church and able to escape told radio station RMC the attackers burst into the church.", "\n\n\"Everyone in the church was screaming, ‘Stop it, stop it! ", "You don’t know what you are doing.’ ", "They forced him (the priest) to kneel down. ", "He tried to defend himself,\" said the nun, identified by the station as Sister Danielle.", "\n\n“I reacted when they attacked Jacques. ", "I ran out quickly. ", "They were busy attacking him, so they didn’t see me leave. ", "They filmed themselves. ", "They preached a sermon in Arabic near the altar. ", "It was horrible. ", "Jacques was an extraordinary priest,\" she told the station.", "\n\nThe French Interior Ministry spokesman, Pierre-Henry Brandet, said the investigation into the incident would be led by anti-terrorism prosecutors. ", "An unidentified person was taken into police custody as part of the investigation, Le Figaro reported.", "\n\nThe Vatican issued a statement from Krakow, Poland, where Pope Francis was visiting, saying,\n\nthe attack hits particularly hard “because this horrific violence took place in a church, a sacred place in which the love of God is announced, and the barbaric murder of a priest and the involvement of the faithful.”", "\n\nDiebel reported from New York.", "\n\nCLOSE\n\nA French security official confirms police have killed the two attackers who used knives to take hostages in a church near the city of Normandy." ]
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0.004422
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[ "“Every person has two homelands, his own and Syria”\n\n— Historian Andre Parrot (Former director of the Louvre Museum).", "\n\nSince nearly century Ottomans committed massacres against the Armenians claimed the lives of more than a million and a half Armenians, now trying to restore these neo-Ottoman massacre in Kesab, but with different tools!", "\n\n150 Christian citizens of Israel demonstrated today (Mar. 23) outside the European Union’s delegation in Tel Aviv against the EU’s silence in relation to what they termed “the ethnic cleansing of Christians throughout the Middle East.” ", "The protesters demanded that the EU act on their own cry for human rights and fight for the Christians throughout the Middle East, who are quickly becoming extinct everywhere but Israel.", "\n\nLast week the Christian Lobby sent a letter to the EU Ambassador in Israel and 18 other western Ambassadors protesting their inactions. “", "We, the members of the Christian Lobby in Israel, found it appropriate to turn to you and cry out about the human and citizens’ rights condition of our Christian brothers across the Middle East.", "\n\nThe slaughter, persecution, discrimination, apartheid, the ethnic cleansing, and all the crimes committed against the Indigenous Aramaic & Christians of the Middle East, in Egypt, Syria, Iraq, Gaza, Lebanon and the Palestinian Authority, among others, and continue to be committed without any intervention of the Western countries,” the letter states.", "\n\nIn the Letter the CL demand that the EU take action. “", "We are turning to you as someone who represents a Western country, which engraved the values of human and citizens’ rights on its flag. ", "Get up and take action. ", "Prove to the slaughtered and the persecuted, and to yourselves, that you believe in those values and act accordingly, wholeheartedly, and not half way.”", "\n\nA recent study warns that Christianity is at the risk of being wiped out in the biblical heartlands of the Middle East. ", "According to the London Daily Telegraph, which cites the study, 10% of Christians worldwide – approximately 200 million – are “socially disadvantaged, harassed or actively oppressed for their beliefs.”", "\n\nWith over 2.3 billion Christians around the world, the study notes that Christians face the most persecution in the region of the world where Christianity first originated – the Middle East.", "\n\nAccording to The Counter Jihad Report “Prominent indicators confirm that the U.S. is the chief facilitator of the persecution of Christians around the world today.” ", "It is astonishing that this is what the United States would devolve to in the 21st century.", "\n\nAccording to the recently released 2014 World Watch List, which ranks the 50 nations where Christians are most persecuted, Syria is the third worst nation in the world in which to be Christian, Iraq is fourth, Afghanistan fifth, and Libya 13th. ", "All four countries receive the strongest designation, “extreme persecution” (other designations are “severe,” “moderate,” and “sparse” persecution).", "\n\nAside from being so closely and harshly ranked, these four nations have something else in common: heavy U.S. involvement. ", "Three—Iraq, Afghanistan, and Libya—were “liberated” thanks to U.S. forces, while in the fourth, Syria, the U.S. is actively sponsoring “freedom fighters” against the regime, many of whom would be better labeled “terrorists.”", "\n\nWhile most Americans are shielded from the true nature of the war by the U.S. media’s reluctance to report on it, Arabic media, websites, and activists daily report and document atrocity after atrocity—beheadings and bombed churches, Christians slaughtered for refusing to convert to Islam, and countless abducted for ransom or rape—at the hands of those whom the U.S. supports.", "\n\nIt’s enough to point out that “the largest massacre of Christians in Syria,” to quote a top religious leader, was left wholly unreported by any major U.S. news network. ", "The massacre took place in Sadad, an ancient Syriac Orthodox Christian habitation, so old as to be mentioned in the Old Testament.", "\n\nIn late October, the U.S-supported “opposition” invaded and occupied Sadad for over a week, till ousted by the nation’s military. ", "Among other atrocities, 45 Christians—including women and children—were killed, several tortured to death; Sadad’s 14 churches, some ancient, were ransacked and destroyed; the bodies of six people from one family, ranging from ages 16 to 90, were found at the bottom of a well (an increasingly common fate for “subhuman” Christians).", "\n\nThe jihadis even made a graphic video (with English subtitles) of those whom they massacred, while shouting Islam’s victory-cry, “Allahu Akbar” (which John McCain equates to a Christian saying “thank God”). ", "Another video, made after Sadad was liberated shows more graphic atrocities.", "\n\nThe worst Christian massacre—complete with mass graves, tortured-to-death women and children, and destroyed churches—recently took place in Syria, at the hands of the U.S.-supported jihadi “rebels”; and the U.S. government and its “mainstream media” mouthpiece are, as usual, silent (that is, when not actively trying to minimize matters).", "\n\nWhere is the worldwide outcry against this unspeakable evil? ", "The millions of victims of jihad must speak in one voice and cry, Defeat these supremacist savages.", "\n\n‘Largest Massacre of Christians in Syria’ Ignored\n\nConfirmed: U.S. Chief Facilitator of Christian Persecution\n\nChristians rally in Israel against Muslim discrimination – See more at: http://pamelageller.com/2014/03/christians-rally-israel-muslim-discrimination.html/#sthash.RZ5vw9T0.dpuf\n\nChristian protesters demanded that the EU act on their own cry for human rights and fight for the Christians throughout the Middle East, who are quickly becoming extinct everywhere but Israel. ", "The U.S. is “the chief facilitator of the persecution of Christians around the world today according to this report.” ", "It is astonishing that this is what the United States would devolve to in the 21st century. ", "According to the recently released 2014 World Watch List, which ranks the 50 nations where Christians are most persecuted, Syria is the third worst nation in the world in which to be Christian, Iraq is fourth, Afghanistan fifth, and Libya 13th. ", "All four countries receive the strongest designation, “extreme persecution” (other designations are “severe,” “moderate,” and “sparse” persecution). ", "Where is the worldwide outcry against this unspeakable evil? ", "The millions of victims of jihad must speak in one voice and cry, Defeat these supremacist savages. – ", "See more at: http://pamelageller.com/2014/03/christians-rally-israel-muslim-discrimination.html/#sthash.wRLT0Gb5.dpuf\n\nA Coalition of Christians and Muslims, made up of Assyrians, Armenians, Greeks, and Syrians – American citizens in Los Angeles recently demonstrated in front of the Turkish Consulate under the title “Stop your aggression against the Syrian people”. ", "Turkey, a NATO member state, has with other NATO states and alongside Qatar and Saudi Arabia been a major contributor to the violence that has beset Syria for the last 3 years.", "\n\nForeign Jihadi Rebels Loot Homes, Take Hostage, Brutally Kill Females, Kids To Death\n\nThe worst massacre of Christians in Syria so far — complete with mass graves, tortured-to-death women and children, and destroyed churches — recently took place at the hands of the U.S.-supported jihadi “rebels”; and the U.S. government and its “mainstream media” mouthpieces are, as usual, silent (that is, when not actively trying to minimize matters).", "\n\nChristianity in Syria\n\nThe archbishop in Syria: “We have shouted for aid to the world but no one has listened to us”\n\nSyria’s Christians face new threat — “convert, submit to Islam or face sword”\n\nSyria Christians Pray for Peace in Damascus as Rebels Close In\n\nAl-Qaeda Rebels in Syria Tell Christians to Pay Up or Die\n\nThe church in Syria\n\n–\n\n–\n\n–\n\n–\n\nHelp Syrian Christians:\n\nRadical Islamist rebels running the northern Syrian city of Raqqa have made the Christians living in the area an offer they can’t refuse: pay for protection, convert to Islam, or “face the sword.”", "\n\nThousands of Syrians, including large numbers of Christians, have fled from their homes, especially in the Homs and Hama governorates and more recently Damascus and Aleppo. ", "There have been reports of the targeting of Christians by both government and opposition sides. ", "Several prominent Syrian Christians have been killed.", "\n\nMost Church leaders point out that any such targeting is not religiously motivated but is either politically motivated or is criminal activity for economic gain. ", "Many Christians fear that radical Islamist groups are becoming more influential, and that this may lead to increased hostility towards Christians and other minorities. ", "They fear that they may becomemore vulnerable to criminal activity, including kidnapping-for-ransom incidents." ]
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[ "An excellent cup of coffee starts with fresh coffee beans. ", "The NESCO® Professional Burr Grinder delivers the consistently even grind and lower heat generation that ensure the maximum flavor retention of your coffee. ", "Select from 17 grind settings from espresso to French press. ", "Hopper holds 8.8 ounces - over a half pound. ", "You can even grind your own flax seeds in our burr mill!", "\n\nAlthough I purchased this grinder elsewhere, I would like to create a balanced review of this product. ", "Have had it for over a year with no problems. ", "It's a plate burr grinder not a conical burr. ", "If you want a conical one, they run from $200 to several hundred dollars. ", "This has been faithful but, you must remember to clean out the port where the grinds come out. ", "No big deal though. ", "Do It about once a week and you'll it'll give you a great cup of coffee. ", "Mine is still going strong, with company, several pots a day.", "\n\n2 out of 5\n\nCovalent BVerona, PA\n\nSomewhat Disappointed\n\nNov. 18, 2013\n\nI bought the Bean Grinder thinking it would improve the taste of the coffee by providing a more uniform grind. ", "The grinder arrived quickly, and I was anxious to see how using a burr grinder would be an improvement over a blade grinder. ", "Initially, I followed the grind settings to match the type of my coffee maker. ", "I chose the middle grind settings for a typical drip coffee maker and a melitta filter cone. ", "At that setting, the coffee was far too weak using the same amount of coffee I used with the blade grinder. ", "Each day I used a finer grind setting until I reached the finest grind, but the coffee was still weaker than I that produced by the blade grinder using a similar amount of coffee. ", "Consequently, rather than increase the amount of coffee used, I opted to go back to the blade grinder which has again produced a stronger brew. ", "Although this grinder did not perform as I had hoped for a drip grinder, it worked well using a french press. ", "Unfortunately, I am too lazy to use the french press on a daily basis because my french press does not make enough coffee for two people.", "\n\n5 out of 5\n\nSteffanie C\n\nGreat Grinder!", "\n\nApr. 20, 2013\n\nI bought this grinder for my Boyfriend for Christmas. ", "We use it almost every morning. ", "So far so good. ", "It grinds the beans up efficiently and we have a great pot of coffee every morning with little fuss.", "\n\n2 out of 5\n\nGail W\n\nMotor Didn't Last but a few uses!", "\n\nMar. 27, 2013\n\nI bought the profesional coffee grinder, thought it would last better, I might have had it a year, only used maybe 3 or 4 times, last night I turned it on walked away and when I turned back it was Smoking, I think the motor burned up, won't work.", "\nNot a Good Product! ", "Very Dissapointed!", "\n\nLearn How to Make Jerky with Nesco Jerky Spice, Jerky Kits, and Dehydrator\n\nMaking Beef Jerky, Venison Jerky and Turkey Jerky in your home with Nesco Jerky Seasonings is fun and easy.", "\n\nNesco Jerky Spice, Nesco Jerky Kits and Nesco Food Dehydrators make fun and easy to make Jerky! ", "Free Dehydration Recipes of all kinds and instructions on how to make Jerky are here at nesco.com.", "\n\nNesco is known for their Roasters and American Harvest for their Dehydrators but combined into Nesco/American Harvest we have extended the product line with Coffee Blade Grinder, Coffee Roasters, Coffee Urn, Food Slicers, Food Grinders, Pressure Cookers, Juice Blenders, Water Kettles, Food Steamers, Bread Machine, Waffle Maker, Toasters, and even a Portable Induction Cooktop." ]
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[ "Q:\n\nWhy does this code leak?", "\n\nWell, here again, this time the compiler is showing me a memory error (leak):\n\notest(18015,0xacae32c0) malloc: * error for object 0x194e734:\n incorrect checksum for freed object - object was probably modified\n after being freed.", "\n * set a breakpoint in malloc_error_break to debug\n\nI'm using clang with ARC activated and STL, this is a C++ file (.cpp).", "\nWhat I found: If I comment the \"delete\" line it runs without problems. ", "It makes me wonder who is freeing my allocated memory (cStr).", "\nBtw. ", "This code takes a query string (arg=abc&arg2=asdb) and returns a map whit those values.", "\nstatic map<string, string> getDecodedQueryString( string qs ) {\n map<string, string> r;\n\n qs = qs+\"&\";\n\n char key[100], value[100], * cStr, *ptr;\n cStr = new char[ qs.length() ];\n memcpy( cStr, qs.c_str(), url.length()-1);\n cStr[qs.length()]=0;\n\n ptr = strtok(cStr, \"&\");\n while ( ptr !", "= NULL && sscanf( ptr, \"%[^=]=%[^&]\", &key, &value ) == 2) { \n r[key]=value;\n ptr = strtok(NULL, \"&\");\n }\n delete [] cStr; //leaking?", "\n\n return r; \n }\n\nThanks\n\nA:\n\nThe problem is likely in these lines:\n cStr = new char[ qs.length() ];\n memcpy( cStr, qs.c_str(), url.length()-1);\n cStr[qs.length()]=0;\n\nEven without the memcpy() (which may have its own problems due to the length of url, as I mentioned above in a comment), the cStr[qs.length()] = 0 writes one byte past the end of the buffer.", "\nIf your compiler has strdup() available (it's nonstandard, but most do), you can replace this with:\ncStr = strdup(qs.c_str());\n// ...\nfree(cStr);\n\nThis saves you from having to mess around with manually allocating bytes, copying them, null terminating in the right place, etc.", "\n\nA:\n\nStr = new char[ qs.length() ];\n...\ncStr[qs.length()]=0;\n\nThat write is invalid, it's one past the end of cStr. ", "If the allocator stored a checksum right after the allocation, and checks it at delete time, you've just stomped on it.", "\n\n" ]
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[ "Getty Images\n\nWarning: Amber Rose's New String Bikini Pics Are So Hot You Might Catch On Fire\n\nAmber Rose is well-known for owning her sexuality, whether it be twerking to celebrate her ex-husband Wiz Khalifa's first No. ", "1 album (RIP Wiz and Amber *sob*) or twerking with her bestie Blacc Chyna.", "\n\nAnd then there was that next-to-naked chain dress she wore to last year's VMAs. ", "But these new pics that the model posted to Instagram today top all of those.", "\n\nIn the snaps, Amber is rocking what can only be described as a string bikini—emphasis on the string.", "\n\nThe string wraps around her back, leaving it ostensibly bare, and provides a littttle more coverage in the front. ", "I guess it's technically a one piece since it all connects?", "\n\nHer captions for the photos include \"Fleekin',\" \"Milfin',\" \"Slayin',\" and \"Stifler's mom.\" ", "Hard to disagree with any of that, honestly. ", "And who cares if it's January, her attire looks like it suits that gorgeous Miami weather. ", "What better way to send a message to your ex than posting some fire pictures on the 'Gram?" ]
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[ "Effects of excess selenomethionine on selenium status indicators in pregnant long-tailed macaques (Macaca fascicularis).", "\nForty pregnant long-tailed macaques were treated daily for 30 d with 0, 25, 150, or 300 micrograms selenium as L-selenomethionine/kg body weight. ", "Erythrocyte and plasma selenium and glutathione peroxidase specific activities, hair and fecal selenium, and urinary selenium excretion were increased by and were linearly related to L-selenomethionine dose. ", "Hair selenium was most sensitive to L-selenomethionine dose, with an 84-fold increase in the 300 micrograms selenium/(kg-d) group relative to controls (r = 0.917). ", "Daily urinary selenium excretion (80-fold, r = 0.958), plasma selenium (22-fold, r = 0.885), erythrocyte selenium (24-fold, r = 0.920), and fecal selenium (18-fold, r = 0.911) also responded strongly to L-selenomethionine. ", "Erythrocyte and plasma glutathione peroxidase specific activities increased 154% and 69% over controls, respectively. ", "Toxicity was associated with erythrocyte selenium > 2.3 micrograms/mL, plasma selenium > 2.8 micrograms/mL, and hair selenium > 27 micrograms/g. Plasma, erythrocyte, and hair selenium concentrations may be useful for monitoring and preventing the toxicity of L-selenomethionine administered to humans in cancer chemoprevention trials." ]
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[ "Millville Motocross 2015\n\nSome shots I took at the 2015 Millville Motocross." ]
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[ "Q:\n\nhow to increase my Left Join query performance in MySQL?", "\n\nI inherited a site running Coldfusion8 and MySQL 5.0.88.", "\nI have two tables - articles (A), which contains product info, and pricelists (P) which includes seller pricelists.", "\nProducts are unique in the products table but may contain multiple entries in the pricelist table (depending on number of pricelists).", "\nIn my product search, I need to get the product info from A and if the user is assigned a pricelist by the seller, I need to also grab the price from the respective pricelist in P.\nI'm pre-compiling all sellerIDs and pricelist names before doing my actual product query, which looks like this:\nSELECT count(A.id) AS total\n FROM arts A\n\n <cfif variables.use_pricelists neq \"\"> \n LEFT JOIN preislisten p ON\n A.ean = P.ean\n AND A.sellerID = p.sellerID\n AND (\n // precompiled list - hardcoded loop\n ( P.list_name = \"-Standard-\" AND P.sellerID = \"2222222222222\" )\n OR\n ( P.list_name = \"I\" AND P.sellerID = \"3333333333333\" )\n )\n </cfif>\n WHERE\n ...\n\nWhile this works... it takes forever. ", "Without checking for pricelists I can run my search in less than 1sec. ", "If pricelists need to checked, it takes 7-10 secs.", "\nQuestion:\nCan this be done faster with a different type of Syntax?", "\nThanks for help! ", " \n\nA:\n\nWhy dont you index your columns, for better performance\nCreate index syntax:\ncreate index idx_ean on preislisten (ean)\n\n" ]
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[ "Get all the latest news on coronavirus and more delivered daily to your inbox. ", "Sign up here.", "\n\nSenate Minority Leader Chuck Schumer, joined by top Democratic senators, on Thursday rolled out a plan that would cancel student loan payments for the duration of the coronavirus national emergency and pay down some outstanding debt.", "\n\nSchumer, D-N.Y., joined by Sens. ", "Elizabeth Warren, D-Mass., Patty Murray, D-Wash., and Sherrod Brown, D-Ohio, unveiled their emergency student loan payment and relief plan, after floating measures to curb the economic impact of COVID-19.", "\n\nTRUMP SAYS HUD WILL SUSPEND ALL FORECLOSURES, EVICTIONS DURING CORONAVIRUS OUTBREAK\n\nThe plan would provide relief to federal student loan borrowers through an “immediate cancellation” of monthly student loan payments during the national emergency, and would “pay down a minimum of $10K for all federal student loan borrowers.”", "\n\nThe plan would require Congress to authorize the Department of Education to make monthly student loan payments on behalf of borrowers, and would “guarantee” the minimum of $10,000 payoff for all borrowers.", "\n\n“The coronavirus outbreak brought with it crushing economic uncertainty, and students and borrowers need targeted, quick relief from payment burdens,” Schumer said in a statement Thursday. “", "Our new proposal would immediately cancel monthly payments, and give students and borrowers a minimum $10K student loan payoff. ", "We must act now to help alleviate the growing financial strain on students and families across the country.”", "\n\nSCHUMER SAYS US 'ALMOST CERTAINLY' WILL SEE A RECESSION AMID COVID-19 PANDEMIC\n\nWarren, whose presidential campaign focused on cancellation of student loan debt, added that the measure would “fix the mistake that still holds back a generation of people and dragged down our economy.”", "\n\nThe suspension of payments would be considered a new policy, separate from the deferment and forbearance options that currently exist for borrowers. ", "The plan would also make all payments made by the Department of Education “tax-free” for borrowers.", "\n\nThe proposal comes after President Trump, last week, announced that he had waived all interest on federal student loans during the coronavirus outbreak rocking the nation.", "\n\nMeanwhile, Trump on Wednesday signed the second coronavirus relief bill into law that provides paid sick leave, unemployment help and free testing to Americans.", "\n\nThe legislation provides 14 days of paid sick days to workers affected by the coronavirus, ensures free testing to everyone, including the uninsured, and expands food aid and boosts unemployment dollars to states.", "\n\nNext up, the Senate and White House have been moving quickly to draft a third round of stimulus legislation that could infuse about $1 trillion into the U.S. economy that has been rattled by school shutdowns, business closures and steep declines in the travel and tourism industry as many Americans are stuck home.", "\n\nSchumer, Warren, Murray and Brown have included the student loan measure as part of Senate Democrats’ “Phase 3” stimulus proposal.", "\n\nAlso expected to be included in the third stimulus package are the \"checks\" that the Trump and the White House have vowed Americans would soon receive. ", "It is unclear, at this point, who would be eligible to receive the relief, and how much cash eligible individuals could expect.", "\n\nThe House and Senate already passed a bipartisan $8.3 billion package to prop up the health-care system to prepare for the influx of sick Americans. ", "The second response bill that was signed into law Wednesday aims to bring relief to workers who lost their jobs and families at home for illnesses, quarantines or caring for kids whose schools have shuttered.", "\n\nAs of Thursday morning, the U.S. currently had more than 9,400 confirmed cases of coronavirus in all 50 states, including Washington, D.C. The U.S., so far, has seen 150 COVID-19-related deaths.", "\n\nThe Trump administration’s task force predicted Tuesday that the number of cases in the U.S. could peak in about 45 days.", "\n\nFox News' Marisa Schultz and The Associated Press contributed to this report." ]
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0.008416
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[ "China cbank says RRR should be appropriately lowered to ease burden on banks\n\n2 Min Read\n\nBEIJING, June 19 (Reuters) - China’s central bank said on Tuesday that banks’ reserve requirement ratios (RRR) should be appropriately lowered to ease the burden on the country’s financial institutions.", "\n\nHowever, as China is still a developing country, it is still necessary to keep the RRR at relatively high levels, the central bank said in a working paper published on its website.", "\n\nThe People’s Bank of China (PBOC) also said it is urgent to transform China’s monetary policy from a quantity-based mode to a price-based mode, adding that authorities will gradually unify market interest rates, deposit and lending rates.", "\n\nThe PBOC in April unexpectedly cut reserve requirement ratios (RRR) for most banks, in a move that was earlier and more aggressive than expected, highlighting concerns over liquidity and the potential economic drag from a trade war with the United States.", "\n\nMany analysts expect further RRR cuts in coming months as China’s economic growth starts to cool under pressure from rising borrowing costs and a regulatory crackdown on riskier lending practices." ]
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[ "---\nabstract: 'Completed in May 2008, the ANTARES neutrino telescope is located in the Mediterranean Sea, 40 km off the coast of Toulon, at a depth of about 2500 m. Consisting of 12 detector lines housing nearly 900 optical modules, the ANTARES telescope is currently the largest neutrino detector in the northern hemisphere. ", "Utilising the Mediterranean Sea as a detecting medium, the detection principle of ANTARES relies on the observation of Cherenkov photons emitted by charged relativistic leptons, produced through neutrino interactions with the surrounding water and seabed, using a 3 dimensional lattice of photomultiplier tubes. ", "In this paper we review the current status of the ANTARES experiment, highlighting some of the results from it’s first year of full operation.'", "\nauthor:\n- 'Anthony M Brown, on behalf of the ANTARES Collaboration'\ntitle: 'The ANTARES Neutrino Telescope: status and first results.'", "\n---\n\n[ altaddress=[brown@cppm.in2p3.fr]{}, address=[CPPM-Centre de Physique des Particules de Marseille, 164, Av. ", "de Luminy, Case 902, Marseille, France.]{},altaddress=[http://antares.in2p3.fr]{} ]{}\n\nIntroduction\n============\n\nNeutrinos afford us a unique view of the Universe. ", "Due to their small interaction cross-section and neutral charge, neutrinos are able to escape, undeflected, from some of the most dense regions of the Universe. ", "As such, neutrinos offer us a unique probe to the most extreme processes occuring in cosmic sources.", "\n\nThe production of high energy neutrinos can occur via the decay of charged mesons, with the charged mesons being produced through the interaction of accelerated hadrons with ambient matter or radiation fields. ", "In an astrophysical scenario, the production of high energy neutrinos is believed to occur in numerous sources where hadronic, or Cosmic Ray, acceleration is believed to take place, such as active galactic nuclei, supernova remnants and microquasars [@source1][@source2][@source3]. ", "As such, neutrino astronomy plays an important role, in the context of a multi-messenger approach, in conclusively proving the origin of Cosmic Ray particles.", "\n\nSearching for neutrino signatures from Dark Matter annihilation is another key goal of neutrino telescopes. ", "Through elastic scattering, weakly interacting massive particles (WIMPs), relic from the Big Bang, are believed to accumulate at the centre of massive celestial objects such as the Sun. ", "This over density of WIMPs results in an increase in the self-annihilation rate of these particles into ordinary matter, producing a measureable high energy neutrino flux in the process.", "\n\nWith a view of pursuing these two main scientific goals, point source and indirect dark matter searches, the ANTARES collaboration has built the largest neutrino telescope in the northern hemisphere, off the coast of southern France. ", "After reviewing the detection technique and performance of the ANTARES neutrino telescope, we will discuss these two scientific goals in light of ANTARES’ first year of complete 12 line operation.", "\n\nThe ANTARES telescope\n=====================\n\nThe ANTARES neutrino telescope consists of 12 detector lines, each approximately 480 meters in length, covering a footprint of approximately $0.1$ km$^2$ [@carr]. ", "The physical dimensions of ANTARES have been optimised for the detection of up-ward going relativistic muons produced through charged-current interactions between muon neutrinos and the water/bedrock surrounding the detector. ", "As such, each detector line supports 75 10-inch photomultiplier tubes housed in pressure resistent glass spheres (OMs), distributed over 25 storeys [@om]. ", "Each storey contains a triple of OMs looking downwards at an angle of 45$^\\circ$ from the horizontal. ", "The vertical spacing between each storey is 14.5 meters, with the first storey located 100 meters above the seabed.", "\n\nThe detection technique of the ANTARES telescope relies on the observations of Cherenkov photons emitted by relativistic charged leptons produced through neutrino interactions with the surrounding water and seabed, using a 3 dimensional lattice of photon detectors. ", "The lepton’s track through the detector is reconstructed using the timing and position of the Cherenkov photon hits on the 3-D lattice. ", "The ANTARES telescope has an energy threshold of  20 GeV for reconstructed neutrino events. ", "However, the telescope’s performance dramatically improves with increasing neutrino energy such that at a neutrino energy of 10 TeV, the ANTARES telescope has an effective area of  0.5 m$^2$ and an angular resolution better than 0.3$^\\circ$. The performance of these important detector characteristics, as a function of neutrino energy, can be seen in Figure 1.", "\n\n![*", "Left:*The effective area of the ANTARES telescope, as a function of neutrino energy. ", "It should be noted that above approximately 1 PeV, the effective area starts to decrease due to the Earth becoming opaque to neutrinos above this energy. *", "Right:* The angular resolution of the ANTARES telescope as a function of energy.](areaangres){height=\".2\\textheight\"}\n\nThe ANTARES telescope started taking data with the connection of the first line in March 2006 [@firstline]. ", "By January 2007, a total of 5 detector lines had been connected and the search for point sources and dark matter neutrino signals commenced. ", "With the detector doubling in size at the start of December 2007, ANTARES was completed at the end of May 2008, with the connection of the final 2 detector lines.", "\n\nAtmospheric Muons\n=================\n\nEven at a depth of 2500 meters under water, atmospheric muons, produced by cosmic ray interactions in the atmosphere, are the dominant signal in the ANTARES detector, with a factor of $10^5$ between triggers from atmospheric muons and atmospheric neutrinos. ", "Nonetheless, atmospheric muons afford us an excellent opportunity to check the systematic uncertainties of the detector.", "\n\nUsing all 5 line data for 2007, the azimuth and zenith distribution of the atmospheric muon triggers were compared to the Monte Carlo (MC) simulations of the detectors response. ", "These MC simulations take into consideration both detector properties, such as angular acceptance of the OMs, and the uncertainties associated with the atmospheric muon production and propagation. ", "As can be seen in Figure 2, there is a good agreement between the data and our MC predictions. ", "This agreement, within the uncertainties, indicating that we understand the properties and the systematic uncertainties of the detector. ", "It should be noted that the zenith distribution of atmospheric muons is dominated by down-going events, and as such, to remove a major source of background, ANTARES only considers up-going events as neutrino candidates. ", "The uneven distribution of the azimuth distribution of atmospheric muons is due to the detector line distribution on the seabed.", "\n\n![", "The azimuth (left) and zenith (right) distribution of the atmospheric muon triggers, with the black dots being the data, the solid line being the MC predictions and the band being the uncertainty associated with these MC predictions.](azimuthzenith){height=\".2\\textheight\"}\n\nCosmic Neutrino Point Source Search\n===================================\n\nTo minimise the effect of atmospheric muons, we only consider up-going events to be neutrino candidates. ", "As such, ANTARES observes the southern sky, and thus, the majority of the galactic plane. ", "From a ‘point source’ point of view this is important since work by the H.E.S.S. collaboration have shown the inner galaxy to be populated with many objects capable of accelerating particles to the TeV energy range needed for TeV neutrino emission [@hess].", "\n\nThe 5 line point source search was performed using two independent and complementary search algorithms: a powerful, unbinned, iterative Expectation-Maximazation method [@em1] [@em2] and a binned, cone search algorith using Poisson statistics [@p1]. ", "Both of these methods were applied using two approaches. ", "Firstly we searched for a neutrino signal from a list of 25 possible source candidates. ", "This list of potential neutrino sources included supernova remnants, microquasars, active galactic nuclei and our Galactic Center, and took into consideration the very high energy $\\gamma-$ray properties of the source as well as the total visibility of the source to the ANTARES detector. ", "Considering a list of potential candidates allowed us to improve the sensitivity of our search since we restrict the number of locations in the sky that is being investigated. ", "The second approach involved a blind search across the whole sky. ", "While this second approach is less sensitive, it is necessary to ensure that clusters of neutrino candidates from other sources not included in the list, are not overlooked. ", "Nonetheless, applying both of these methods, to both search approaches, no neutrino point source was found in the 5 line 2007 data, at 90% confidence level.", "\n\nThe upper limits derived from this 5 line data set, assuming an $E_{\\nu}^{-2}$ spectrum, for the list of 25 candidates, are shown in Figure 3. ", "It should be noted that, while using a data set of only 140 days and using a partially completed detector, ANTARES was able to set upper limits that are comparable, if not better than those set by other southern looking neutrino experiments with multi-year data sets.", "\n\n![", "Neutrino flux upper limits (solid squares) set by the 5 line configuration of ANTARES, for a list of 25 candidate source, compared with results from other experiments (IceCube[@ic1], AMANDA[@ic2], SuperKamiokande [@sk1] and MACRO [@mac1]), at 90% confidence level, assuming an $E_{\\nu}^{-2}$ spectrum. ", "The predicted sensitivity of one year ANTARES data set is also shown.](upper){height=\".25\\textheight\"}\n\nIndirect Dark Matter Search\n===========================\n\nWithin the supersymmetric minimal supergravity (SUSY mSUGRA) framework, the neutralino, $\\chi$, can be the lightest stable SUSY particle. ", "With a mass in the range of GeV to TeV, the neutralino interacts through gravity and the weak force alone, and thus it fulfils all the requirements to be a cold dark matter candidate. ", "In the context of neutrino telescopes, searching for WIMP dark matter candidates involves looking for neutrino fluxes from the core of massive celestial objects such as the Sun, our Galaxy or indeed from the centre of the Earth, where the WIMPS are believed to accumulate.", "\n\nANTARES sensitivity to Neutralino Annihilation\n----------------------------------------------\n\nThe expected neutrino flux from neutralino annihilations in the Sun, in the mSUGRA framework, depends upon four parameters: $A_0$, $m_0$, $m_{1/2}$ and $tan(\\beta)$, where $A_0$ is the universal trilinear coupling, $m_0$ is the universal scalar mass, $m_{1/2}$ is the universal gaugino mass and $tan(\\beta)$ is the ratio of the vacuum expectation values of the two Higgs fields. ", "Using a modified version of the DarkSUSY code [@darks1], the expected neutrino flux was calculated for approximately 4 million different combinations of these four parameters, with each different parameter set being chosen using a random walk method through the parameter space. ", "It should be noted that this flux calculation also takes into consideration neutrino oscillations and absorption within the Sun.", "\n\nCombining these calculated neutrino fluxes with the energy dependent effective area of ANTARES, we can estimate a detection rate for dark matter induced neutrino emission. ", "This estimation is essentially a indication of ANTARES’ ability to probe neutralino properties, such as relic density or mass, and can be seen in Figure 4, along with predictions for the future kilometer cube size expansion (KM3NET [@km3v2]).", "\n\n![", "Sensitivity of the ANTARES and KM3NET to neutrinos produced through neutralino annihilation in the Sun, in the mSUGRA framework. ", "The neutrino flux is integrated above 10 GeV, as a function of neutralino mass. ", "The blue and green data indicate areas of the model parameter space accessible by ANTARES and KM3NET respectively, while the red points are inaccessible to both experiments. ", "The bright data points indicate models that are predicted, within 2$\\sigma$ of the WMAP relic density, the shaded points are those outside of this.](DMsensitive){height=\".25\\textheight\"}\n\nANTARES neutrino flux limit from dark matter annihilation in the Sun.", "\n---------------------------------------------------------------------\n\nThe 5 line data from 2007 was also used to search for neutrino signals from neutralino annihilation in the Sun. ", "Only up-going events when the Sun was below the horizon were considered, resulting in an effective lifetime of 68.4 days. ", "Considering two extreme cases for the neutralino annihilation channel, namely hard (W-boson) and soft (b quark), the size of the search cone around the Sun was optimised before being applied to the data. ", "Using this search cone, limits on the neutrino flux from the Sun, above 10 GeV, were calculated for both the hard and soft channels, following the unified approach method of Feldman and Cousins [@fc1]. ", "These limits can be see in Figure 5.", "\n\n![", "The upper limit on the neutrino flux from neutralino annihilation in the Sun, assuming two extreme cases for the annihilation channel. ", "Set for neutrinos above 10 GeV in energy, these limits were calculated using all 5 line data from 2007.](neuDMflux){height=\".25\\textheight\"}\n\nTo compare ANTARES’ neutrino flux limits from neutralino annihilation, to those set by other experiments, the neutrino flux limit derived in Figure 5 was converted to the corresponding muon flux, integrated above an energy of 1 GeV. These comparisons can be seen in Figure 6. ", "While the limits set by ANTARES in Figure 6 are not as constraining as the other experiments, it should be noted that ANTARES’ flux limits are based on only approximately 70 days of data from the less than half completed detector.", "\n\n![", "The neutrino induced muon flux from the upper limits set in Figure 5, intergrated above a muon energy of 1 GeV. As before, the green data points are from a relic density that is within 2 $\\sigma$ of the WMAP region, with the red and blue show relic densities above and below this relic density respectively.](muDMflux){height=\".3\\textheight\"}\n\nConclusion\n==========\n\nThe ANTARES neutrino telescope was completed in May 2008 with the connection of the last two detector lines. ", "The flux and distribution of atmospheric muons detected by ANTARES have shown that we understand the systematic uncertainties of the now completed telescope. ", "Throughout its construction, ANTARES has been taking data. ", "Data taken during its 5 line configuration stage (March to December 2007) has been used to set competitive flux limits on a list of possible neutrino point sources. ", "Assuming an $E_{\\nu}^{-2}$ neutrino spectrum, the upper limits set by ANTARES’ 5 line data are better then those set by the multi-year data sets of Super-Kamiokande and MACRO experiments. ", "This improvement being a testiment to ANTARES’ unprecedented sensitivity to neutrinos in the 10-100 TeV energy range.", "\n\nThe 5 line data was also used to set limits on the neutrino flux from possible neutralino annihilation in the center of the Sun, assuming both hard and soft annihilation channels. ", "While these upper limits are non-constraining, a similiar study using a data set from the now completed ANTARES detector will allow us to place better limits in the not-to-distant future.", "\n\nAnthony Brown acknowledges the financial support of both the French funding agency ‘Centre National de la Recherche Scientifique’ (CNRS) and the European KM3NET design study grant.", "\n\n[99]{}\n\nHalzen F and Hooper D, Rep. Prog. ", "Phys. ", "65 (2002) 1025 Bednarek W *et al.* ", "New Astron. ", "Rev. 49 (2005) 1 Stecker F W, Phys. ", "Rev. D 72 (2005) 107301 Carr J, for the ANTARES Collaboration, J. Phys. ", "Conf. ", "Ser. ", "136 (2008) 022047 P. Amram *et al.*, ", "ANTARES Collaboration, NIM A484(2002)369 Ageron M *et al.*, ", "ANTARES Collaboration, Astropart. ", "Phys. ", "31 (2009) 277, arXiv:0812.2095 Aharonian F, for the HESS Collaboration, Astrophys. ", "J. 636 (2006) 777A Dempster A P, Laird NM and Rubin D B, J.R. Statist. ", "Soc. ", "Series B 39 (1977) 1 Aguilar J A and Hernandez-Rey J J, Astrop. ", "Phys. ", "29 2 (2008) 117 Hill G C and Rawlins K, Astrop. ", "Phys. ", "19 3 (2003) 393, astro-ph/0209350 Abbasi R *et al.*, ", "IceCube Collaboration, arXiv:0905.2253 Abbasi R *et al.*, ", "IceCube Collaboration, Phys. ", "Rev. D 79 (2009) 062001, arXiv:0809.1646 Desai S *et al.*, ", "SuperKamiokande Collaboration, Astrop. ", "Phys. ", "29 (2008) 42 Ambrosio M *et al.*, ", "MACRO Collaboration, Astrophys. ", "J. 546 (2001) 1038 Gondolo P *et al.*, ", "JCAP 0407 (2004) 008 Feldman G L and Cousins R D, Phys. ", "Rev. D 57 (1998) 3873 <http://www.km3net.org>\n" ]
{ "pile_set_name": "ArXiv" }
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0.010397
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[ "A new breakpoint, telomeric to TEL/ETV6, on the short arm of chromosome 12 in T cell acute lymphoblastic leukemia.", "\nAbnormalities of the short arm of chromosome 12 frequently involve the TEL/ETV6 gene in acute leukemias. ", "In two cases of T cell acute lymphoblastic leukemia with translocation t(12;14)(p13;q11) and t(7;12)(q35;p13), respectively, the breakpoints were located telomeric to the TEL/ETV6 locus. ", "Further fluorescence in situ hybridization (FISH) studies showed that the breakpoint was located between two markers, FGF6 (centromeric) and D12S983 (telomeric) on 12p in both patients. ", "This result suggests that a new chromosomal breakpoint can nonrandomly involve rearrangements in T cell malignancies. ", "The breakpoint on chromosome 14 was localized centromeric to the TRCA/D locus." ]
{ "pile_set_name": "PubMed Abstracts" }
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0.007845
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[ "Clinical and pathological findings related to malnutrition and husbandry in captive giant tortoises (Geochelone species).", "\nA biomedical survey was carried out on the population of giant tortoises housed in some of the major zoological collections in the United Kingdom. ", "Wasting syndrome was diagnosed in individuals which were kept under suboptimal conditions of housing and diet. ", "Clinical manifestations and laboratory and post mortem findings are discussed." ]
{ "pile_set_name": "PubMed Abstracts" }
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0.002066
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