chrom
stringclasses 2
values | pos
int64 10.2k
249M
| ref
stringclasses 4
values | alt
stringclasses 4
values | AC
int64 1
152k
| AN
int64 2
152k
| AF
float64 0
1
| consequence
stringlengths 9
552
| GPN-MSA
float32 -13.59
11.1
|
|---|---|---|---|---|---|---|---|---|
1 | 17,408 | C | G | 1,494 | 142,314 | 0.010498 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,non_coding_transcript_exon_variant | -1.242487 |
1 | 17,415 | G | A | 3 | 152,236 | 0.00002 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,mature_miRNA_variant,non_coding_transcript_exon_variant | 0.009917 |
1 | 17,422 | T | C | 2 | 152,246 | 0.000013 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,mature_miRNA_variant,non_coding_transcript_exon_variant | -0.321382 |
1 | 17,427 | C | A | 1 | 152,260 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,mature_miRNA_variant,non_coding_transcript_exon_variant | -1.069892 |
1 | 17,445 | G | A | 1 | 152,264 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -1.448917 |
1 | 17,452 | C | T | 553 | 143,232 | 0.003861 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | 0.752567 |
1 | 17,453 | G | A | 35 | 152,156 | 0.00023 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -0.042869 |
1 | 17,458 | C | T | 1 | 152,276 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -1.48987 |
1 | 17,463 | G | C | 2 | 152,264 | 0.000013 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -1.520464 |
1 | 17,468 | C | A | 1 | 152,272 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -1.64291 |
1 | 17,472 | G | A | 19 | 152,180 | 0.000125 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -1.646819 |
1 | 17,474 | C | G | 1 | 152,286 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -1.574066 |
1 | 17,478 | C | T | 54 | 151,846 | 0.000356 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -0.256967 |
1 | 17,479 | G | A | 203 | 150,316 | 0.00135 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | 1.357076 |
1 | 17,483 | C | T | 86 | 151,794 | 0.000567 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -0.347159 |
1 | 17,484 | G | A | 229 | 151,106 | 0.001515 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | 0.812031 |
1 | 17,486 | G | C | 1 | 152,284 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -0.914804 |
1 | 17,490 | C | A | 1 | 152,284 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -0.477339 |
1 | 17,492 | C | T | 19 | 151,998 | 0.000125 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -0.792657 |
1 | 17,493 | G | A | 12 | 152,208 | 0.000079 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | 0.337564 |
1 | 17,497 | C | T | 5 | 150,756 | 0.000033 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -0.534438 |
1 | 17,498 | C | G | 4 | 150,750 | 0.000027 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -1.771155 |
1 | 17,500 | C | G | 2 | 152,270 | 0.000013 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -1.894565 |
1 | 17,511 | G | A | 1 | 152,270 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -1.503854 |
1 | 17,511 | G | T | 5 | 152,248 | 0.000033 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -1.537908 |
1 | 17,512 | C | G | 23 | 152,044 | 0.000151 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -1.565342 |
1 | 17,516 | T | A | 1 | 152,258 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -1.34385 |
1 | 17,516 | T | C | 30 | 152,170 | 0.000197 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -0.905091 |
1 | 17,517 | G | A | 4 | 152,230 | 0.000026 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -1.749225 |
1 | 17,519 | G | T | 432 | 146,666 | 0.002945 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -1.978857 |
1 | 17,522 | G | A | 2 | 152,244 | 0.000013 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -1.61585 |
1 | 17,525 | C | A | 6 | 152,236 | 0.000039 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -1.649883 |
1 | 17,532 | C | A | 41 | 152,092 | 0.00027 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -1.360714 |
1 | 17,538 | C | A | 62 | 149,336 | 0.000415 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -1.621979 |
1 | 17,538 | C | T | 2 | 150,212 | 0.000013 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -0.64464 |
1 | 17,542 | G | C | 6 | 152,162 | 0.000039 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -1.663853 |
1 | 17,543 | G | A | 1 | 152,178 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -1.911225 |
1 | 17,544 | G | C | 1 | 152,174 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -1.489179 |
1 | 17,551 | C | A | 1 | 152,152 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -1.865908 |
1 | 17,551 | C | T | 3 | 152,152 | 0.00002 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -1.7342 |
1 | 17,555 | G | A | 1 | 152,086 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -1.89326 |
1 | 17,556 | C | T | 1,674 | 143,098 | 0.011698 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -2.204389 |
1 | 17,559 | G | A | 1 | 150,788 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -1.784071 |
1 | 17,559 | G | C | 2,840 | 144,408 | 0.019667 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -1.858727 |
1 | 17,563 | G | A | 33 | 151,578 | 0.000218 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | 0.729621 |
1 | 17,569 | C | A | 12 | 151,508 | 0.000079 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -3.111238 |
1 | 17,572 | G | A | 2 | 151,606 | 0.000013 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | 2.001817 |
1 | 17,577 | C | T | 3 | 150,614 | 0.00002 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -1.932585 |
1 | 17,584 | C | T | 1 | 150,318 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | 0.067859 |
1 | 17,585 | G | A | 6 | 150,234 | 0.00004 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | 0.48524 |
1 | 17,586 | G | A | 3 | 150,188 | 0.00002 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -0.619802 |
1 | 17,586 | G | T | 2 | 150,192 | 0.000013 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -1.314474 |
1 | 17,588 | C | G | 24 | 150,178 | 0.00016 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -1.416233 |
1 | 17,589 | C | T | 229 | 149,022 | 0.001537 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -1.311183 |
1 | 17,592 | C | G | 31 | 150,012 | 0.000207 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -1.580888 |
1 | 17,594 | C | T | 3,276 | 132,414 | 0.024741 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | 0.471059 |
1 | 17,596 | C | T | 13 | 149,764 | 0.000087 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -4.094283 |
1 | 17,599 | G | A | 1 | 149,600 | 0.000007 | downstream_gene_variant,splice_region_variant&intron_variant&non_coding_transcript_variant,upstream_gene_variant | -4.186172 |
1 | 17,603 | T | C | 1 | 149,216 | 0.000007 | downstream_gene_variant,splice_region_variant&intron_variant&non_coding_transcript_variant,upstream_gene_variant | -2.050294 |
1 | 17,605 | C | A | 1 | 149,196 | 0.000007 | downstream_gene_variant,splice_donor_variant&non_coding_transcript_variant,upstream_gene_variant | -8.797672 |
1 | 17,606 | A | G | 245 | 143,532 | 0.001707 | downstream_gene_variant,splice_region_variant&non_coding_transcript_exon_variant,upstream_gene_variant | -5.061177 |
1 | 17,607 | G | A | 1 | 148,552 | 0.000007 | downstream_gene_variant,splice_region_variant&non_coding_transcript_exon_variant,upstream_gene_variant | -4.888049 |
1 | 17,607 | G | T | 1 | 148,554 | 0.000007 | downstream_gene_variant,splice_region_variant&non_coding_transcript_exon_variant,upstream_gene_variant | -7.451001 |
1 | 17,613 | C | T | 3 | 148,454 | 0.00002 | downstream_gene_variant,non_coding_transcript_exon_variant,upstream_gene_variant | -3.774601 |
1 | 17,614 | G | A | 6,270 | 126,212 | 0.049678 | downstream_gene_variant,non_coding_transcript_exon_variant,upstream_gene_variant | 1.213949 |
1 | 17,617 | G | A | 1 | 148,156 | 0.000007 | downstream_gene_variant,non_coding_transcript_exon_variant,upstream_gene_variant | -3.254828 |
1 | 17,618 | G | A | 4 | 147,916 | 0.000027 | downstream_gene_variant,non_coding_transcript_exon_variant,upstream_gene_variant | -5.899392 |
1 | 17,622 | T | G | 1 | 146,440 | 0.000007 | downstream_gene_variant,non_coding_transcript_exon_variant,upstream_gene_variant | -7.337619 |
1 | 17,626 | G | A | 1,019 | 139,824 | 0.007288 | downstream_gene_variant,non_coding_transcript_exon_variant,upstream_gene_variant | -3.462853 |
1 | 17,636 | G | A | 12 | 145,404 | 0.000083 | downstream_gene_variant,non_coding_transcript_exon_variant,upstream_gene_variant | -7.014556 |
1 | 17,637 | A | C | 2 | 144,188 | 0.000014 | downstream_gene_variant,non_coding_transcript_exon_variant,upstream_gene_variant | -8.676538 |
1 | 17,645 | G | C | 4 | 146,148 | 0.000027 | downstream_gene_variant,non_coding_transcript_exon_variant,upstream_gene_variant | -6.996089 |
1 | 17,648 | C | G | 1 | 146,638 | 0.000007 | downstream_gene_variant,non_coding_transcript_exon_variant,upstream_gene_variant | -5.265926 |
1 | 17,677 | C | T | 2 | 149,174 | 0.000013 | downstream_gene_variant,non_coding_transcript_exon_variant,upstream_gene_variant | -2.567493 |
1 | 17,688 | C | T | 201 | 148,390 | 0.001355 | downstream_gene_variant,non_coding_transcript_exon_variant,upstream_gene_variant | -2.866876 |
1 | 17,691 | C | T | 1 | 149,224 | 0.000007 | downstream_gene_variant,non_coding_transcript_exon_variant,upstream_gene_variant | -5.461165 |
1 | 17,697 | G | C | 17,539 | 116,050 | 0.151133 | downstream_gene_variant,non_coding_transcript_exon_variant,upstream_gene_variant | -4.733067 |
1 | 17,707 | G | A | 1 | 149,074 | 0.000007 | downstream_gene_variant,non_coding_transcript_exon_variant,upstream_gene_variant | -3.471418 |
1 | 17,716 | G | A | 169 | 146,138 | 0.001156 | downstream_gene_variant,non_coding_transcript_exon_variant,upstream_gene_variant | 1.305676 |
1 | 17,723 | G | A | 1 | 148,842 | 0.000007 | downstream_gene_variant,non_coding_transcript_exon_variant,upstream_gene_variant | -6.045098 |
1 | 17,728 | G | T | 109 | 146,906 | 0.000742 | downstream_gene_variant,non_coding_transcript_exon_variant,upstream_gene_variant | -4.96367 |
1 | 17,736 | G | A | 1 | 148,016 | 0.000007 | downstream_gene_variant,non_coding_transcript_exon_variant,upstream_gene_variant | -4.480055 |
1 | 17,736 | G | C | 3 | 148,016 | 0.00002 | downstream_gene_variant,non_coding_transcript_exon_variant,upstream_gene_variant | -6.713208 |
1 | 17,748 | A | G | 60 | 145,886 | 0.000411 | downstream_gene_variant,splice_region_variant&intron_variant&non_coding_transcript_variant,upstream_gene_variant | 0.204803 |
1 | 17,753 | C | T | 74 | 144,280 | 0.000513 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -1.446889 |
1 | 17,754 | A | G | 4 | 145,608 | 0.000027 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -1.347188 |
1 | 17,756 | G | A | 1 | 145,352 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -1.557477 |
1 | 17,759 | G | A | 1 | 144,998 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -1.675505 |
1 | 17,764 | A | G | 1 | 143,712 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -1.389989 |
1 | 17,765 | G | C | 96 | 139,718 | 0.000687 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -1.512768 |
1 | 17,767 | G | A | 538 | 141,118 | 0.003812 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -1.624345 |
1 | 17,772 | T | C | 1 | 140,852 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -1.211736 |
1 | 17,784 | G | A | 1 | 135,264 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -1.461595 |
1 | 17,791 | C | T | 18 | 131,084 | 0.000137 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -1.482524 |
1 | 17,818 | A | C | 1 | 108,402 | 0.000009 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -1.762764 |
1 | 17,829 | G | A | 836 | 98,160 | 0.008517 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -0.905757 |
1 | 17,838 | A | C | 1 | 80,018 | 0.000012 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -1.481314 |
1 | 17,843 | A | G | 93 | 79,844 | 0.001165 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | 0.065699 |
1 | 17,844 | T | C | 52 | 81,108 | 0.000641 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | -0.931705 |
1 | 17,854 | G | A | 10 | 75,536 | 0.000132 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,upstream_gene_variant | 1.85815 |