chrom
stringclasses 2
values | pos
int64 10.2k
249M
| ref
stringclasses 4
values | alt
stringclasses 4
values | AC
int64 1
152k
| AN
int64 2
152k
| AF
float64 0
1
| consequence
stringlengths 9
552
| GPN-MSA
float32 -13.59
11.1
|
|---|---|---|---|---|---|---|---|---|
1 | 16,107 | G | A | 1 | 127,486 | 0.000008 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -0.861429 |
1 | 16,109 | C | A | 4 | 127,944 | 0.000031 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -0.872456 |
1 | 16,117 | C | A | 1 | 135,066 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.48894 |
1 | 16,127 | C | A | 43 | 145,706 | 0.000295 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.409497 |
1 | 16,133 | C | T | 2 | 148,110 | 0.000014 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.359723 |
1 | 16,139 | C | T | 23 | 149,432 | 0.000154 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -0.176469 |
1 | 16,141 | C | T | 256 | 147,628 | 0.001734 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -0.262146 |
1 | 16,142 | G | A | 15 | 150,196 | 0.0001 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | 1.410596 |
1 | 16,151 | G | A | 1 | 151,354 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.359275 |
1 | 16,153 | G | A | 1 | 151,424 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.179761 |
1 | 16,184 | C | T | 2 | 152,092 | 0.000013 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -3.117781 |
1 | 16,186 | A | C | 1 | 152,070 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -3.619974 |
1 | 16,187 | C | A | 2 | 152,126 | 0.000013 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -3.486403 |
1 | 16,191 | G | A | 1 | 152,050 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.68794 |
1 | 16,192 | C | A | 1 | 152,142 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.75861 |
1 | 16,192 | C | T | 1 | 152,134 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.677751 |
1 | 16,200 | G | C | 1 | 152,170 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.409928 |
1 | 16,206 | T | A | 25 | 151,194 | 0.000165 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | 1.095082 |
1 | 16,216 | A | C | 1 | 152,224 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -0.849833 |
1 | 16,221 | C | T | 5 | 152,220 | 0.000033 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -0.189104 |
1 | 16,228 | T | C | 1 | 150,424 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.146179 |
1 | 16,243 | C | G | 5 | 152,200 | 0.000033 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | 0.017838 |
1 | 16,243 | C | T | 2 | 152,202 | 0.000013 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | 1.43562 |
1 | 16,246 | G | C | 1 | 152,236 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.565192 |
1 | 16,257 | G | C | 7,005 | 114,936 | 0.060947 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -0.176244 |
1 | 16,259 | T | C | 1 | 152,082 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -0.945339 |
1 | 16,263 | G | A | 1 | 152,136 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.341967 |
1 | 16,263 | G | T | 1 | 152,134 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.484895 |
1 | 16,266 | C | T | 1 | 152,140 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.289664 |
1 | 16,278 | G | A | 1 | 151,964 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.251431 |
1 | 16,278 | G | C | 2 | 151,962 | 0.000013 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.474702 |
1 | 16,280 | T | C | 1,655 | 149,862 | 0.011044 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -0.800054 |
1 | 16,282 | G | A | 4 | 151,688 | 0.000026 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -0.894387 |
1 | 16,282 | G | C | 3 | 151,690 | 0.00002 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.22009 |
1 | 16,295 | A | G | 6 | 150,750 | 0.00004 | TF_binding_site_variant,downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.562268 |
1 | 16,296 | G | T | 1 | 150,754 | 0.000007 | TF_binding_site_variant,downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.641873 |
1 | 16,298 | C | G | 5 | 146,408 | 0.000034 | TF_binding_site_variant,downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -0.995547 |
1 | 16,300 | C | T | 1 | 150,334 | 0.000007 | TF_binding_site_variant,downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.190528 |
1 | 16,306 | T | C | 1 | 150,262 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.316791 |
1 | 16,307 | G | A | 1 | 150,460 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | 0.739614 |
1 | 16,309 | A | G | 1 | 150,424 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.012036 |
1 | 16,310 | G | A | 11 | 150,476 | 0.000073 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | 0.698739 |
1 | 16,322 | A | C | 1 | 150,472 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.50585 |
1 | 16,323 | A | C | 3 | 150,516 | 0.00002 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | 0.486382 |
1 | 16,325 | G | A | 1 | 150,576 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -0.495978 |
1 | 16,327 | G | A | 1 | 150,508 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.655635 |
1 | 16,350 | C | T | 1 | 150,866 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | 0.986961 |
1 | 16,358 | T | C | 1 | 151,314 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.239444 |
1 | 16,362 | T | C | 4 | 151,418 | 0.000026 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -0.545536 |
1 | 16,365 | G | A | 1 | 151,544 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.293306 |
1 | 16,365 | G | C | 15 | 151,538 | 0.000099 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.854726 |
1 | 16,374 | G | C | 1 | 151,722 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.67097 |
1 | 16,380 | G | A | 3 | 152,084 | 0.00002 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.614004 |
1 | 16,381 | G | A | 1 | 152,146 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.3792 |
1 | 16,383 | A | G | 1 | 152,178 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | 1.202053 |
1 | 16,392 | C | A | 1 | 152,252 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.45661 |
1 | 16,395 | C | T | 1 | 152,272 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.486428 |
1 | 16,397 | C | A | 19 | 152,236 | 0.000125 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.411374 |
1 | 16,398 | T | G | 1 | 152,282 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -0.241064 |
1 | 16,404 | A | G | 1 | 152,290 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.891427 |
1 | 16,424 | G | A | 10 | 152,288 | 0.000066 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -0.489115 |
1 | 16,443 | A | G | 18 | 152,130 | 0.000118 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -0.738196 |
1 | 16,445 | A | G | 1 | 152,304 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.963329 |
1 | 16,485 | T | C | 1 | 152,230 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -3.108191 |
1 | 16,487 | T | C | 9,468 | 140,496 | 0.06739 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -3.700708 |
1 | 16,488 | T | A | 1 | 152,306 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -5.705648 |
1 | 16,555 | C | G | 1 | 151,240 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -0.933238 |
1 | 16,567 | G | C | 559 | 149,682 | 0.003735 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -0.49698 |
1 | 16,571 | G | A | 8,130 | 110,666 | 0.073464 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | 1.297947 |
1 | 16,572 | C | T | 7 | 149,848 | 0.000047 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -2.735535 |
1 | 16,576 | A | C | 310 | 146,624 | 0.002114 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -2.919811 |
1 | 16,592 | A | T | 40 | 148,898 | 0.000269 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -2.242534 |
1 | 16,613 | G | A | 4 | 148,110 | 0.000027 | downstream_gene_variant,non_coding_transcript_exon_variant | -3.451374 |
1 | 16,615 | G | A | 1 | 147,890 | 0.000007 | downstream_gene_variant,non_coding_transcript_exon_variant | -4.181238 |
1 | 16,620 | G | A | 27 | 147,200 | 0.000183 | downstream_gene_variant,non_coding_transcript_exon_variant | 0.032986 |
1 | 16,627 | C | T | 1 | 145,130 | 0.000007 | downstream_gene_variant,non_coding_transcript_exon_variant | -1.843357 |
1 | 16,634 | C | T | 4 | 141,468 | 0.000028 | downstream_gene_variant,non_coding_transcript_exon_variant | 0.065972 |
1 | 16,647 | G | A | 34 | 143,344 | 0.000237 | downstream_gene_variant,non_coding_transcript_exon_variant | -0.193084 |
1 | 16,660 | G | C | 3 | 147,244 | 0.00002 | downstream_gene_variant,non_coding_transcript_exon_variant | -4.660491 |
1 | 16,668 | G | A | 11 | 147,536 | 0.000075 | downstream_gene_variant,non_coding_transcript_exon_variant | 0.496982 |
1 | 16,669 | G | A | 2 | 136,620 | 0.000015 | downstream_gene_variant,non_coding_transcript_exon_variant | -2.092478 |
1 | 16,670 | T | C | 1 | 142,702 | 0.000007 | downstream_gene_variant,non_coding_transcript_exon_variant | -1.047366 |
1 | 16,677 | T | A | 1 | 53,120 | 0.000019 | downstream_gene_variant,non_coding_transcript_exon_variant | -3.383739 |
1 | 16,679 | G | A | 1 | 147,872 | 0.000007 | downstream_gene_variant,non_coding_transcript_exon_variant | -4.662776 |
1 | 16,682 | G | A | 5,673 | 121,522 | 0.046683 | downstream_gene_variant,non_coding_transcript_exon_variant | -4.187462 |
1 | 16,689 | T | G | 35 | 118,426 | 0.000296 | downstream_gene_variant,non_coding_transcript_exon_variant | -1.258673 |
1 | 16,690 | G | A | 3 | 133,682 | 0.000022 | downstream_gene_variant,non_coding_transcript_exon_variant | -2.756001 |
1 | 16,695 | G | A | 3 | 147,770 | 0.00002 | downstream_gene_variant,non_coding_transcript_exon_variant | -1.648293 |
1 | 16,710 | A | G | 1 | 100,346 | 0.00001 | downstream_gene_variant,non_coding_transcript_exon_variant | -3.007244 |
1 | 16,713 | T | G | 2 | 38,348 | 0.000052 | downstream_gene_variant,non_coding_transcript_exon_variant | -3.903987 |
1 | 16,717 | G | A | 1 | 150,530 | 0.000007 | downstream_gene_variant,non_coding_transcript_exon_variant | -5.869214 |
1 | 16,720 | G | A | 8 | 150,750 | 0.000053 | downstream_gene_variant,non_coding_transcript_exon_variant | -5.039338 |
1 | 16,756 | T | C | 17 | 151,398 | 0.000112 | downstream_gene_variant,non_coding_transcript_exon_variant | -3.491883 |
1 | 16,779 | T | G | 2 | 151,740 | 0.000013 | downstream_gene_variant,intron_variant&non_coding_transcript_variant | -1.301076 |
1 | 16,785 | G | T | 1 | 151,838 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant | -1.42692 |
1 | 16,786 | T | G | 1 | 151,706 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant | -1.802419 |
1 | 16,807 | G | C | 1 | 151,254 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant | -1.089067 |
1 | 16,813 | G | A | 2 | 151,558 | 0.000013 | downstream_gene_variant,intron_variant&non_coding_transcript_variant | -1.874158 |
1 | 16,816 | G | A | 2 | 151,512 | 0.000013 | downstream_gene_variant,intron_variant&non_coding_transcript_variant | -1.709434 |
1 | 16,820 | C | G | 2 | 151,412 | 0.000013 | downstream_gene_variant,intron_variant&non_coding_transcript_variant | -1.605469 |