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Flow chart of treatment modalities for the bleeding trauma patient discussed in this guideline. APTT: activated partial thromboplastin time; ASS: acetylsalicylsalicylic acid; CT: computed tomography; FAST: focused abdominal sonography for trauma; Hb: haemoglobin; INR: international normalised ratio. | 99.9 |
Anteroposterior radiograph of the skull showed massive sclerosis of the skull bone associated with significant cortical hyperostosis and enlargement of the mandible secondary to cortical new bone formation (fig 1). Lateral skull radiograph showed sclerosis of the skull base (arrow) and hyperostosis of the calvaria (fig 2). Coronal MRI imaging showed significant calvarial/facial and mandibular hyperostosis (fig 3). Anteroposterior radiograph of the radius showed cortical new bone formation associated with subperiosteal thickening. Note marked bloating along the diaphysis with sparing of the epi-metaphyseal components associated with expansion of the bone marrow cavity and a persistent-like deformity (fig 4). Anteroposterior radiograph of the tibia showed a thick and broad ballooning occupies the diaphyses (proximally and distally) there is gaining in the diameter comes from subperiosteal new bone apposition by intramembraneous bone formation (fig 5). | 99.94 |
Anteroposterior radiograph of the radius showed cortical new bone formation associated with subperiosteal thickening. Note marked bloating along the diaphysis with sparing of the epi-metaphyseal components associated with expansion of the bone marrow cavity and a persistent-like deformity (fig 4). | 99.94 |
The described technique for treating venous thrombosis in microvascular flap surgery avoids the opening of the arterial anastomosis. This procedure has been successfully applied in several patients at the Departments for Maxillofacial Surgery of the Universities of Mainz and Regensburg as presented in this case example from Mainz (see table 1). | 99.7 |
We immediately revise venous complications. This regiment is also described by other authors . Local heparin injection is a well-known procedure in the management of venous thrombosis . We avoid the opening of the artery by injecting high dose heparin into the pedicle artery. | 99.94 |
Twenty-seven cases were in children 3–12 years of age (median 9 years). All case-patients were hospitalized. The median duration from admission to death was 4 days (range 1–25 days). All 4 patients who survived >10 days were admitted to intensive care units. | 99.6 |
SCC grading-HE stained sections viewed at low power ×25 showing poorly differentiated squamous cell carcinoma infiltrating as poorly cohesive single cells and nests of tumour cells. There is no clear demarcation between the tumour invasion front and surrounding tissue. | 99.6 |
Two interviews described cases where medication (topicals and IV fluids) had been given but had not been prescribed on the system and so an eP administration record could not be made. Record review identified several cases where oxygen had been given but not prescribed. | 99.7 |
Our first patient was a 71-year male who had undergone intra-pericardial pneumonectomy 18 years earlier for squamous cell carcinoma of the left lung. His coronary angiogram revealed severe stenosis in left main stem and further significant disease in right coronary artery. He underwent urgent coronary artery bypass grafting (CABG) using cardiopulmonary bypass and antegrade cold blood cardioplegia. Saphenous vein (SVG) was used to graft left anterior descending artery (LAD) and posterior descending branch of the right coronary artery. | 100 |
In addition to routine blood test and spirometry the pre-operative workup of these patients included computerised tomography of the chest to assess distortion of intra-thoracic anatomy. Preoperative inspiratory muscle training is found to be beneficial reducing the incidence of postoperative pulmonary complications following thoracic and upper abdominal surgery . In an attempt to improve the pulmonary function both the patients were admitted prior to their surgery for intensive chest physiotherapy and incentive spirometry. | 99.7 |
Involvement of right side was seen in 30 patients and the left side in 16 patients. No patient had bilateral involvement. All of the patients were vaginally delivered with vertex presentations. Obstetrical history revealed that most mothers were multiparous and 8 of the patients were delivered with the help of forceps or vacuum. The mean birth weight of the patients was 4.5 kg (3–6.6 kg). | 99.4 |
There are several treatment protocols for forced eruption involving removable and fixed appliances depending upon the specific clinical situation. This case demonstrates a technique for orthodontic extrusion of upper premolar with two roots by a sectional fixed appliance and subsequent prosthodontic rehabilitation. | 99.94 |
This treatment was carried out in a General Dental practice with limited orthodontic materials. Applying this technique to posterior teeth has been suggested but rarely demonstrated in the literature. A study done involving extrusion of more than 100 cases of premolar teeth has been reported by a different technique involving direct bonded brackets and nickel-titanium segmented arch wire . | 99.75 |
Aldosterone synthase deficiency is a rare cause of hyperreninaemic hypoaldosteronism and its genetic and molecular basis is more heterogeneous than previously described. It should be suspected in infants without virilisation presenting with salt-wasting or in adults presenting with stress-induced hyperkalaemia and a history of failure to thrive in childhood. Our case illustrates the clinical significance to recognize this condition as it has a good long-term prognosis when adequate fludrocortisone replacement is instituted. | 99.9 |
The maintenance of response or partial response from the end of the ECT course ranged from 6 to 13 months at the last observation period during the rTMS course. Only one patient had a partial worsening of symptoms. The maintenance of the response for the patients in this case series was clinically significant in the context of the chronicity of their illnesses. | 99.7 |
Molecular analysis of Patient 6 from primary and metastatic tumors group. Representative results of microsatellite PCR analysis of DNA from the neoplasms associated with Patient 6. T1 refers to the primary lung cancer and T2 refers to the metastatic tumor. The identity of each microsatellite marker analyzed is indicated. | 99.44 |
Molecular analysis of Patient 3 from synchronous lung tumor with different histological types group. T1 refers to the lung cancer of adenocarcinoma and T2 refers to the lung cancer of squamous carcinoma. The identity of each microsatellite marker analyzed is indicated. | 99.8 |
Rheumatoid arthritis (RA) is a disease characterized by inflammation of the synovial membrane. Franks in 1969 reported that women are approximately three times more likely to be affected than men with RA. Abhijeet and Shirish in 2010 also concluded the same findings . We also reported a case of RA in female patient. | 99.94 |
Kurita et al. in 2004 reported that functional and parafunctional loading elicit adaptive and degenerative changes in load bearing joints including TMJ. In TMJ the anterosuperior part of the mandibular condyle and the posterior slope and inferior part of the articular eminence are assumed to bear the greatest load .Abhijeet and Shirish in 2010 also reported that erosion of superior part of mandibular condyle is most commonly seen in rheumatoid arthritis . Present case reported posterosuperior portion of condyle to be affected. | 99.9 |
Results of laboratory diagnostic tests for patients 1 and 2 and magnetic resonance imaging results of bilateral basal ganglia and caudate hyperintensities on fluid attenuated inversion recovery/T2-weighted sequence in patient 1; and T2/magnetic resonance imaging results of bilateral temporal hyperintensities on fluid attenuated inversion recovery/T2-weighted sequence in patient 2. | 99.9 |
A 24-year-old HIV positive homosexual Danish male with no other chronic diseases was admitted to the hospital with four days of febrile episodes and thoracic pain with intermittent stabbing pain in both arms. He had also had bilateral leg pain worst at night time. He denied having had any kind of rash or genital ulcers. There had been no traumas in connection to the onset of pain. | 100 |
In conclusion we describe an atypical presentation of syphilis in a young HIV infected male with osteitis in vertebrae including the dens of axis caused by T pallidum. MRI changes lead to bone biopsy and subsequently the diagnosis of syphilis obtained by specific PCR technique. The rare location of a syphilitic osteitis and the diagnostic approach make this case unique. | 99.94 |
At age 35 this caucasian male initially presented with a simple partial seizure on the left side in 2006. There were no other diseases reported in the medical history of the patient. Karnofsky Performance Status (KPS) on admission was 90 and his antiepileptic drug therapy was based on oxcarbazepine and clobazam. Magnetic resonance imaging (MRI) showed a mass lesion (3 centimeter (cm) × 2 cm) in the right central region (see Figure 1). | 100 |
In August 2011 the patient was admitted to the neurosurgical department again because of a fast progressing tetraparesis and ischuria over a few days. The tetraparesis was accentuated on the left side. KPS was 30 at this time. MRI of the brain showed that the local contrast enhancing tumor was under control and not responsible for the deteriorating neurological status. CT and MRI scan of the cervical spine revealed a tumor infiltration of the fifth and sixth vertebra with an invasion into the spinal canal and large paravertebral tumor masses (see Figure 2). | 100 |
We can reaffirm with our case that especially young glioblastoma patients have the potential to develop extraneural metastasis. We conclude that especially in the case of the so called “long-term survivors” with repeated surgeries the possibility of extraneural metastasis should be anticipated and an appropriate staging should be performed early when suspected. | 99.94 |
Axial CT slices of patient # 3 after contrast material was intravenously administered. A target lesion with a SLD of 84 mm is localized near the minor pelvis before (A) and after (C) six cycles of first-line chemotherapy. (B) The arrow represents a mesenteric peritoneal carcinosis (non-target lesion) in the same patient that is level with the lower edge of the liver prior to chemotherapy. A significant amount of ascites associated with the non-target lesion is also observed (B). (D) Both non-target lesions are absent after the completion of chemotherapy. | 99.94 |
A 38-year-male patient presented with two-month-old history of pain abdomen and feeling of heaviness in right lower abdomen. Pain was severe in intensity and relieved only after taking medication. Patient also gave a history of lump in the abdomen. General physical and systemic examination was normal. Local examination of abdomen and pelvis revealed a hard mass measuring around 15 × 10 cm in size in the right iliac region. Complete hemogram of the patient was suggestive of dimorphic iron deficiency anemia with thrombocytosis. Routine blood biochemistry parameters of the patient were within normal limits. | 100 |
The present study exemplifies the use of NGS approach for detailed diagnosis of the specific clinical pathology and identification of causative mutations for rare genetic disorder. This approach has been recently advocated for both diagnosis and therapy . The obtained genetic data for this cases were successfully used clinically for the peripartum anesthetic management of the previously described patient . Comprehensive genetic analysis through NGS based approaches will increasingly be helpful in establishing the diagnosis of Factor V deficiency (or other genetic coagulation disorders) and thereby improve patient management. | 99.75 |
Series of frontal sections through the brainstem and midbrain of case SC4 demarcating the location of retrogradely labeled neurons after inoculation of the left m. acromiodeltoideus (survival time of 79 h after inoculation) and FITC labeled varicosities after injection into the superficial layers of the right SC (2 days before the muscle inoculation). Red symbols indicate retrogradely labeled cells with adjacent tectofugal fibers and varicosities. Other conventions as in Figure 3. | 99.8 |
Magnetic resonance imaging findings showed the desmoid tumor (arrows) with lower signal intensity on T1-weighted image (a) and high signal intensity on T2-weighted image (b and c). Note that the desmoid tumor was next to contrast-filled transverse colon. (a and b) Axial plane. (c) Coronal plane. | 99.5 |
A case report of a patient who had chronic dystrophic epidermolysis bullosa (EB) for 20 years healed with honey impregnated dressing in 15 weeks after conventional dressings and creams failed. This illustrates the usefulness of honey as an anti-inflammatory agent. Chronic inflammatory process has risk of cancer development. | 99.94 |
Antero-posterior radiograph of a 56 year-old male patient ´ s left shoulder with an implanted inverted total shoulder prosthesis Delta at 52 months of follow-up. Radiological analysis reveals "grade 2 = notch with condensation" of infraglenoidal scapular notching according to Nerot. | 100 |
Antero-posterior radiograph of a 64 year-old female patient ´ s right shoulder with an implanted inverted total shoulder prosthesis Delta at 39 months of follow-up. Radiological analysis reveals "grade 4 = erosion over the inferior screw with extension under the base plate" of infraglenoidal scapular notching according to Nerot. | 100 |
Antero-posterior radiograph of a 74 year-old female patient ´ s left shoulder with an implanted inverted total shoulder prosthesis Delta at 64 months of follow-up. Radiological analysis reveals with "grade 3 = erosion up to the inferior screw" of infraglenoidal scapular notching according to Nerot. | 100 |
Antero-posterior radiograph of a 71 year-old female patient ´ s left shoulder with an implanted inverted total shoulder prosthesis Delta at 31 months of follow-up. Radiological analysis reveals "grade 4 = erosion over the inferior screw with extension under the base plate" of infraglenoidal scapular notching according to Nerot. | 100 |
Antero-posterior radiograph of a 75 year-old female patient ´ s left shoulder with an implanted inverted total shoulder prosthesis Delta at 32 months of follow-up. Radiological analysis reveals "grade 4 = erosion over the inferior screw with extension under the base plate" of infraglenoidal scapular notching according to Nerot. | 100 |
Antero-posterior radiograph of a 69 year-old female patient ´ s right shoulder with an implanted inverted total shoulder prosthesis Delta at 44 months of follow-up. Radiological analysis reveals with "grade 3 = erosion up to the inferior screw" of infraglenoidal scapular notching according to Nerot. | 100 |
The follow-up lumbar puncture [see Table 1] noted pleocytosis with now predominantly lymphocytes. Total CSF-protein levels decreased from 2470 mg/l to 1510 mg/l. The total CSF cell count showed an increase to 360 cells – Fluorescence Activated Cell Sorting [FACS] analysis was used to ruled out clonal expansion of hematological cells in the CSF and cytologic analysis did not detect any malignant cell formations. | 99.94 |
Four patients developed superficial wound infection at the cervical site including one patient who underwent global fusion. Graft site infection was noted in three patients. All seven patients responded to antimicrobial therapy. Two patients developed transient recurrent laryngeal nerve palsy and one patient developed a trachea-esophageal fistula which healed with conservative management. Fifteen patients needed a tracheostomy for their management. | 99.75 |
One year after stopping the cyclophosphamide--but while still on the prednisolone--the symptoms of dyspnea upon exertion returned. A radiograph and HRCT of the chest were therefore repeated to ascertain the cause of dyspnea. We observed increased thickening of the interlobular septa with sub-pleural emphysema and tubular bronchiectasis of his right lower lung (Figures 3 and 4). Supportive treatment with low-flow oxygen therapy and breathing exercises were prescribed because of the chronic pulmonary fibrosis. | 100 |
Patient A developed a wound haematoma after 45 minutes following a superficial parotidectomy (lasting 60 minutes with no drain inserted initially) and was taken back to theatre where an evacuation procedure was undertaken. A drain was inserted at this procedure with further use of Floseal®. The drain was removed after 48 hours with no complications. | 99.94 |
Patient C underwent an elective left hemithyroid procedure (lasting 120 minutes) that was complicated by haematoma formation observed while the patient was still in recovery. The patient was taken back to theatre approximately two hours later for evacuation of the haematoma where a small venous bleed was identified and cauterised with bipolar diathermy. Further Floseal® was used and drain insertion was undertaken. The drain was removed after 48 hours with no further complications. | 100 |
The observation was performed by two clinical physicians to maintain consistency. Two weeks after transplantation was considered the skin graft survival observation endpoint. The area of skin graft survival was observed using the grid number method and graft survival rate was calculated using the following formula: Skin graft survival area/original graft area ×100. | 99.9 |
MfERG recordings made prior to white PLGA membrane transplantation showed retinal responses in the visual streak to be identical in the left and right eyes and comparable with previously obtained baseline recordings (data not shown). No preimplantation recordings were obtained for the blue membranes. | 99.5 |
Total gastrectomy + splenectomy + D2 lymphadenectomy could be performed at 40 POD after the first surgery. The final pathological diagnosis was pStageIV (TNM classification: T3N1M1) with por 2 and No. 10 lymph node metastasis (Japanese Classification of Gastric Carcinoma). | 99.94 |
Radiographic evaluation of the surgical treatment at pre- and postoperative stages. (A and B) Radiograph showing cartilaginous lesions or enchondromas predominantly localized in the upper part of the humerus (A) and the lower part of the radius (B) of the 16 years old boy affected with Ollier disease. (C) A huge tumor of the proximal humerus with massive cortical destruction and soft tissue extension was noticed at age 25 of the patient. (D) The radiograph on the postoperative day 2 (anteroposterior view). The prosthesis was well in place after the surgery. (E) The radiograph on 1 year after the surgery (anteroposterior view). The prosthesis was still well in place. (F) The radiograph on 8 years after the surgery (anteroposterior view). The prosthesis remained well in place. (G and H) The radiographs of the ulna and radius of the limb were also taken at age 33 of the patient (8 years after the surgery). There were no signs for malignant transformation in those lesions. | 99.94 |
Wide resection of the tumor with a prosthetic replacement of the proximal humerus. (A) The range of tumor resection. (B) The humeral osteotomy was made 2 cm distal to the tumor extent to ensure a wide margin. (C) Overview of the resected tumor. (D) The tumor resection cavity. (E) Placement of the proximal humeral prosthesis. The shaft preparation with cementing the prosthesis (arrow indicated) was designed for supporting the reattachment of muscles and/or tendons to the prosthesis. (F) Histologic confirmation for the diagnosis of chondrosarcoma of the proximal humerus. | 99.8 |
The gynecological structures demonstrated an enlarged myomatous uterus with areas of low attenuation which were interpreted as representing areas of necrosis. The estimated anterior-posterior diameter dimension of this large hypodensity was 10.8 cm (Figure 1(a)). Subsequent MRI revealed an intramural lesion with a large submucosal component which distorted the underlying endometrium. | 99.94 |
Patient and allograft survival at 6 months: There was one death 13 days post-transplantation due to severe anoxic brain injury following sepsis. The remaining 48 patients were alive with functioning grafts at the end of study. There were no episodes of CMV infection or BK virus nephritis during follow-up and no infusion reactions to Thymoglobulin were documented. | 99.94 |
He was admitted in local hospital for the same for 3 days; here he was diagnosed as having pneumonia with right lower zone consolidation. Antibiotics and symptomatic treatment were given. There was no improvement in his condition so he was referred to our institution for confirmed diagnosis and management. | 100 |
Patient had a past history of CV stroke followed by facial palsy 5 years back. Patient was nondiabetic but was on regular antihypertensive drugs. He did not have any history of chronic illnesses or surgery in the past. Patient had an agricultural background. | 99.94 |
Histological appearance 6 weeks after the surgery. The right eye with conventional hang-back recession (A) and the left eye with fibrin glue after hang-back recession (B) showed similar findings. Rectus muscle at the insertion site was separated from the scleral surface and surrounded by fibrous tissue which was attached to the sclera. Inflammatory cells were rarely seen. Red blood cells were found more frequently in the right eye. Bar = 200 μm. | 99.94 |
A growth of dark hair within the vitiliginous patch on both patients was probably due to activation of follicular melanocytes by a nonspecific effect of contact dermatitis. Vitiliginous patches at the sites of contact with DPCP may be the consequence of postinflammatory hypopigmentation. | 99.7 |
Our patients undergo whole-body multislice CT which is defined as imaging of the thorax and upper abdomen in arterial phase and imaging of the abdomen and pelvis at portal phase. Detailed imaging information was retrieved from the hospital's Picture Archiving and Communication System (PACS). We obtained the time that the CT was performed from the CT scan information. We categorised reports as “normal” or “abnormal” for the plain pelvic and chest X-rays and CT scans. Abnormal was defined as any finding which was likely to be due to the trauma for which the patient was admitted. Imaging findings of past injuries or incidental pathology were ignored. | 99.8 |
Molecular and clinical details of a patient from Family B with a mutation in the NR2E3 gene. A: Pedigree is shown (explanation of symbols as in Figure 1). B: Sequence of the NR2E3 gene in normal control (top) and patient B2 with homozygous deletion+insertion (bottom). The dinucleotide undergoing deletion is boxed in top panel. The arrows in the bottom panel mark the inserted sequence. C: Fundus montage of right eye of patient B-2 (aged 10 years) with NR2E3 mutation showing peripheral graying of retina with white flecks due to RPE atrophy with macular sparing with hardly any disc or arterial changes. The right temporal retina had unexplained sub-retinal scarring/gliosis and no obvious bone corpuscular pigment migration at this age. | 99.94 |
(A–E) These images are temporal bone CT in patient 7. (A) Cochlear hypoplasia type III with less than two turns is indicated by a black arrow. (B) The vestibular aqueduct (white asterisk) was enlarged and seen in a circular shape in the axial view. The lateral semicircular canal was slightly hypoplastic and the vestibular was dilated (black arrowhead). (C) The facial nerve ran inferior to the hypoplastic cochlea and displayed an obtuse angle between the labyrinthine and tympanic segments (white arrowhead). (D) The modiolus (white arrow) was present but defective and hypoplastic. (E) The ossicular chain (white arrow) seen in the coronal view was positioned in a different angle compared to the normal control. (F–K) These images are temporal bone CT in normal control. | 99.9 |
Temporal bone CT and temporal MRI findings of patient 10 demonstrating enlarged vestibular aqueduct in a circular shape. (A–F) Axial view of temporal bone CT shows enlarged vestibular aqueduct (black arrows) observed as a circular shape with a diameter significantly larger than that of the posterior semicircular canal (black arrowhead in Fig. S1A). (F–K) Axial view of temporal MRI also exhibited enlargement of the endolymphatic duct (white arrows) whereas the endolymphatic sac was not enlarged (white arrowhead in Fig. S1K). | 99.94 |
A and B: lateral (A) and palmar (B) view of the right index finger: palmar swelling in the area of the base and middle phalanx after 4 weeks of corticosteroid therapy. Compared to the initial finding the swelling is already diminished. On both pictures the indurated scar is prominent. | 99.94 |
Apart from enlarged soft tissue X-rays of the finger were unsuspicious. MRI-scans showed a considerable palmar soft tissue swelling with an enhancement of contrast medium with contact to the flexor tendon (Figure 2A and B). Blood tests including complete blood count and the inflammation markers C-reactive protein and erythrocyte sedimentation rate remained without pathological findings. | 99.94 |
This case exemplifies that TdP due to acquired long QT syndrome is a serious and potentially fatal complication in IE. Multiple factors including antimicrobial drugs are at an increased risk for the development of acquired long QTc syndrome. Physicians should therefore always maintain a high degree of clinical suspicion for the presence of long QT syndrome in patients with IE and should be aware of the QT-prolonging side effects of drugs they prescribe for these patients. | 99.9 |
a Cholangiogram through a T-tube that shows the presence of a bile leak due to traumatic rupture of the main bile duct (small arrow). b The T-tube was exchanged to a locking pigtail drain catheter that drained externally. Cholangiographic control revealed that the leak was sealed a couple of weeks later | 99.94 |
a Biliorrhea post open cholecystectomy occurred and ERCP failed to access the biliary tree due to concomitant stenosis of the common bile duct (CBD). Percutaneous puncture of the right side bile ducts and contrast injection. Cholangiogram revealed leakage from the ducts of Luscka (black arrow) and severe obstruction of the CBD. b The CBD was catheterised and a self-expandable metallic stent was deployed in order to drain the bile away from the side of leak | 99.94 |
a Laceration and obstruction of common hepatic duct post laparoscopic cholecystectomy that led to biloma formation. b Percutaneous CT-guided drainage of the biloma. c Cholangiographic picture that confirms the communication of the collection with the biliary system. Surgical repair of the bile ducts followed | 99.94 |
A patient with intra-hepatic stenosis and bile leak post biliodigestive anastomosis. a Percutaneous access that revealed the stenotic area (arrow). b Dilation of the stenotic tract. c The patient returned 9 years later with a new leak that was initially embolised with coils (black arrow) and then (d) a covered stent was deployed to seal the leak | 100 |
A & B. Two magnifications of a section of abdominal wall fixed seventeen days following intraperitoneal infection and stained with Mayer’s Haemalum and Eosin. Intestine and gonad of T. nasalis are identified. Note that no collagen capsule and no inflammatory cells were observed around T. nasalis within the muscle tissue. Diameter of the larva: 33 μm. | 99.9 |
We present the case of this patient because we found Hashimoto's thyroiditis in struma ovarii and we wanted to emphasize the difficulties in management of this rare condition. There is a paucity of data in the past literature regarding the optimal follow-up modality for such patients; our findings may be auxiliary to other clinicians. | 99.94 |
The patients were followed-up monthly for three months three monthly for six months and yearly for two years. Any patients having complications were admitted through emergency and investigated with hematological examination and ultrasonography of the abdomen. | 99.9 |
The sections revealed moderately dense collagenous connective tissue with collagen bundles arranged in a haphazard manner. Connective tissue was relatively avascular along with scanty inflammatory cell infiltrate showing dense wavy bundles of collagen fibers containing numerous fibrocytes and fibroblasts. The overlying epithelium was hyperplastic with elongated rete ridges. The histopathologic features led to the final diagnosis of idiopathic gingival fibromatosis. | 99.94 |
The case was followed up for 6 weeks postoperatively and then every 3 months for 2 years. The mobility of the teeth was reduced to physiologic at the end of 3 months. No recurrence was observed within 2 years. Patient is still following the follow-up regime. Mild recurrence in the right maxillary posterior palatal segment was seen after 1 year (Figure 3). | 100 |
Surgical procedures have been shown to trigger symptoms in perioperative tissue of patients with BD by a pathergy-like effect. Pathergy-like phenomena have been described in patients with BD after surgery of the gastrointestinal tract (as gastrointestinal ulcers at the operative site) and after vascular surgery (presenting as localized vasculitis and aneurysm) . There are only a few case reports of BD disease flares triggered by head and neck surgery. A case of neuro-Behçet disease was reported after a tooth extraction . Another patient with BD developed myositis of the calf after a tonsillectomy . | 99.9 |
Tonsillitis and a tonsillectomy triggered small vessel vasculitis of the neck soft tissue in our patient. The diagnosis was delayed due to an uncommon disease presentation and was eventually confirmed by tissue biopsy. BD is known for its variable clinical manifestations and disease flares can be triggered by oropharyngeal surgery. Whether preoperative immunosuppression would have prevented disease activation in our patient remains unclear. | 99.94 |
CW and IK were the treating physicians on the internal medicine ward where our patient was hospitalized. They wrote the manuscript and were responsible for the revision of the manuscript. DS was the consultant immunologist. He was involved in the diagnosis and treatment of Behçet’s disease. MT was responsible for the histological diagnosis in this patient and provided the histological images presented. All authors read and approved the final manuscript. | 99.7 |
Combined figure. A. Pedigree of Family 4792 with ARNSHL Affected subjects are denoted in black. Arrow indicates the proband; B. Audiogram of affected subjects showed hearing loss ranged from severe to profound.; C. Electropherograms analysis of MYO15A in family 4792 showing the compound heterozygous mutations (c.IVS25 + 3G > A and c.8375C > T) co-segregated with the phenotype. | 99.94 |
The proband is a female of Caucasian origin. She was found to have moderate thrombocytopenia during a laboratory test more than 20 years ago. She was misdiagnosed with immunologic thrombocytopenic purpura at the time because steroid therapy and splenectomy did not improve her platelet count. Her pedigree was constructed through genealogical studies (Figure 1 ). | 100 |
Our patient had no history of alcohol abuse or other metabolic diseases and no family history of hereditary hemochromatosis (HH). Clinical examination revealed no abnormalities. Further laboratory evaluation showed normal liver enzymes and normal hematological parameters. | 99.94 |
Robinson and Driscoll were the first group to report such an injury where it was seen in conjunction with a simultaneous avulsion of the tibial end of the ligament as well. The first report of an isolated avulsion of the femoral origin of the ACL was reported by Eady et al. . Tohyama et al. reported a case of consecutive avulsion fractures involving the ACL in which a tibial-sided avulsion fracture was successfully treated and was followed 35 months later by a second injury in which the femoral attachment of the ACL was avulsed. | 99.94 |
There have been no reports on the results of stem-retaining 2-staged revision. We hypothesized that infection after hip arthroplasty could be treated without removal of a well-fixed cementless stem. We assessed the outcome of such a procedure in 19 patients. | 99.25 |
Pedigree and clinical findings. A. Pedigree of the Turkish family. B. Post-mortem examination of foetus III:4 at 19 weeks of gestation showed bowed extremities and pes equinovarus. C. X-rays of foetus III:4 revealed beaded ribs and multiple fractures of tubular bones. | 99.94 |
The first few sessions of Phase Two were devoted to obtaining a greater understanding of the difficulties that the patient had with her husband. The patient reported that she tended to ‘go along with’ whatever her husband wanted to do but that sometimes she would become ‘fed up’ and shout at him. She appeared very distressed when describing this. | 99.9 |
One participant reported feeling depressed the day after an ART session which subsequently resolved. This participant completed treatment and follow-up. Three additional non-study (treatment) related events were reported: (i) light headedness with poor balance and memory; (ii) headache at the time of the 2-month follow-up due to having five teeth pulled; and (iii) delayed ability to complete 2-month follow-up questionnaires due to a car accident. | 99.94 |
Deep vein thrombosis three-dimensional CT (DVT 3D CT) angiography showing the cardiac mass and thromboemboli before the surgery. (A) Maximum intensity projection (MIP) image shows pulmonary artery thromboembolism involving the right lower lobar artery and its segmental branches. (B) Computed tomography (CT) angiography of the pulmonary artery shows multiple large thrombi in the right atrium and right ventricle. | 99.8 |
The histopathology of the surgical specimen revealed this to be a cardiac metastasis from known cervical squamous cell carcinoma (Figure 3A). Additional HPV DNA genotyping of the metastatic lesion revealed HPV-16 consistent with the primary lesion. Cardiac metastasis should be the cause of the pulmonary embolic events and right heart failure that she had suffered. | 99.94 |
All patients were evaluated postoperatively and were typically ready to receive systemic therapy within 1 to 2 weeks after surgical resection. One exception was in the patient who experienced a postoperative biloma. This patient was ready to receive systemic therapy 4 weeks after surgical resection. | 99.94 |
Abdominal ultrasonography showed a 10X2 cm collection in left perirenal area. The fluid was aspirated and cultured. The smears of aspirated material showed nonseptated hyphea consistent with mucor. Antifungal therapy mainly composed of amphotericin B was started. However fever continued and further investigation by CT scan revealed cystic hypoattenuated lesion in the medial aspect of left kidney (Figure 1). | 100 |
In order to detect point mutations and small homo-/heterozygous interstitial deletions/insertions all four exons of MECP2 were sequenced in both the twins. PCR amplification of complete exons including exon-intron boundaries were carried out using published primers and the amplification products were sequenced using ABI3700 genetic analyzer. | 99.8 |
The median duration of follow-up was 123 months (10.25 years) for the 4 pineocytoma patients (range 71--242 months). At the end of follow-up 3 patients were still alive and remained free of disease. Patient 3 developed late cerebral and spinal tumor seeding 46 months after radiation treatment and underwent salvage radiotherapy to the spinal axis with a TD of 39.6 Gy. She died 28 months later due to progressive disease. | 99.94 |
Patient 14 developed tumor progression of the suprasellar tumor 6 months after fractionated radiation therapy. Reirradiation with stereotactic radiosurgery was performed (TD 12.5 Gy@80% isodose). The patient also developed spinal tumor seeding 11 months later and died shortly afterwards. | 99.94 |
No paraplegia case was noted for eight months after 125I implantation. Tail swaying and defecating and urinating were the same as normal. The Tarlov scale was five for all the treatment animals from starting to eight months. Hematological analysis is shown in Table 2. All the data suggest banna mini-pigs had stable physical conditions within the eight months. | 99.94 |
The patients were scheduled for follow-up visits every 6 months after the initial surgery. Follow-up consisted of a routine physical examination and computed tomography (CT) or magnetic resonance imaging (MRI) of the primary site. A combined 18 F-FDG positronemission tomography (PET) and CT scan was performed on one patient. Patient follow-up was reported up to the date last seen in the clinic. | 99.94 |
A woman in her 60s visited our hospital because of upper abdominal pain. She had a history of appendicitis and cholelithiasis. She was diagnosed with acute gallstone pancreatitis based on her laboratory data and abdominal computed tomography (CT) findings. | 100 |
A full-term newborn girl developed abdominal distention with emesis and failure to pass meconium 12 h after birth. The pregnancy had been complicated by an antenatal diagnosis of polyhydramnios and dilated bowel loops. The mother was in good clinical condition without any history of vitamin deficit before or during pregnancy. | 99.94 |
The pedigree of the litter with the affected puppies was traced back for six generations and phenotype data were supplemented for these dogs. The dam and sire of the affected puppies were unaffected. A litter of maternal half-siblings was inconspicuous as well as all littermates of the dam and granddam and further siblings of all progeny of ancestors. The maternal granddam (dog F) and maternal great-granddam (dog G) had healthy litters from different sires. An autosomal recessive or dominant inheritance was ruled out due to normal parents and ancestors as well as no obvious inbreeding in the six generations. The mode of inheritance suggests an X-recessive transmission through the dam or the germline of either grandparent (Figure 2). | 99.9 |
Figure 3Sagittal MRI scans of the TMJ in a patient with DDWoR and disc deformity. A: Closed-mouth position: articular disc in anterior position in relation to the condyle; osteophyte visible in the condyle. B: Open-mouth position: the condyle does not reduce the dislocated disc. | 99.94 |
Sagittal MRI scans of the TMJ in a patient with DDWoR and disc deformity. A: Closed-mouth position: articular disc in anterior position in relation to the condyle; osteophyte visible in the condyle. B: Open-mouth position: the condyle does not reduce the dislocated disc. | 99.9 |
Mild inspiratory dyspnoea and increased inspiratory sounds during tracheal and laryngeal auscultation were noted at rest. Symptoms progressed to moderate to severe inspiratory dyspnoea under stress and an audible inspiratory wheeze became evident. Serum biochemistry revealed raised alkaline phosphatase activity (144 μ/L; reference interval < 95); other values were within normal range. | 99.94 |
Left lateral cervical radiograph revealed a crescent shaped soft tissue opaque mass of 14 mm × 32 mm in the tracheal lumen at the level of the 5th and 6th vertebrae. The mass was at its widest in dorsal aspect of the trachea and extended to the opposite wall of the trachea | 99.94 |
Multiple head CTs. (A) Multiple lobar hemorrhages (October 5th); (B) cerebral hemorrhage of bilateral frontal lobe and left parietal lobe breaking into the ventricle (October 6th); (C) bilateral cerebral hemisphere hemorrhage breaking into the ventricle and subarachnoid space with cerebral hernia (October 12th); (D) slight high density irregular shadow in the right frontal and left parietal lobes and edema in the surrounding brain parenchyma show that the ventricle was obviously under pressure and the brain midline shifted right (October 12th). CT = computed tomography. | 99.3 |
Panoramic radiograph showing excessive marginal bone loss affecting all the dental implants in the mandible supporting fixed prostheses (a). Clinical image showing the advanced bone destruction around the implants at the incisors and left premolar regions (b). Clinical image showing the preservation of the pre-existing bone upon implant removal with the counter-torque regions (c). Panoramic radiograph showing the maintenance at this stage of 3 implants to support the provisional prosthesis in the mandible (d) | 99.9 |
Implant placement surgery after 4 months of healing (a). Immediate loading of the new implants and the explanation of the implant at the left first molar (b). Panoramic radiograph showing the case finished with 12 months of follow-up (c). Clinical image showing the definitive screw-retained prostheses (d) | 99.94 |
The girl was born by vaginal delivery after an uneventful pregnancy. Birth parameters were at mean (birth weight: 3.200 kg; birth length: 49 cm; and occipital frontal circumference (OFC) 34 cm). She had global developmental delay diagnosed since 2 years old. She sat at 10 months and learned to walk at 22 months. | 99.94 |
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