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embedding_all-mpnet-base-v2
sequence
embedding_multi-qa-mpnet-base-dot-v1
sequence
embedding_all-MiniLM-L12-v2
sequence
24967410
3objective
Noncardiac chest pain ( NCCP ) is seen more frequently in young population and in these patients loss of function is evolving in social and professional areas .
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176,000
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24967410
3objective
The aim of the study is to evaluate the levels of anxiety and somatic perception in patients with chest pain presenting to cardiology clinic .
1
176,001
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24967410
2methods
Fifty-one patients with noncardiac chest pain and @ healthy controls were included in the study .
2
176,002
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24967410
2methods
All participants performed self-report based health anxiety inventory ( HAI ) , somatosensory amplification scale ( SAS ) , and Toronto alexithymia scale ( TAS ) .
3
176,003
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24967410
4results
The patient group had significantly higher scores on the SAS , HAI-@ , and HAI-T scales compared to controls ( P < @ , P = @ , and P = @ , resp . )
4
176,004
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24967410
4results
SAS , HAI-@ , and HAI-T scores were significantly higher in female patients than male ( P = @ , @ , and @ , resp . )
5
176,005
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24967410
4results
There were significant differences in all TAS subscale scores between two groups .
6
176,006
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24967410
4results
Patients , who had total TAS score more than @ , also presented higher levels of health anxiety ( P = @ ) .
7
176,007
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24967410
1conclusions
Anxiety , somatic symptoms , and the exaggerated sense of bodily sensations are common in patients with NCCP .
8
176,008
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24967410
1conclusions
These patients unnecessarily occupy the cardiology outpatient clinics .
9
176,009
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24967410
1conclusions
These negative results can be eliminated when consultation-liaison psychiatry evaluates these patients in collaboration with cardiology departments .
10
176,010
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25876339
3objective
To compare the differences in the clinical efficacy on Alzheimer 's disease between acupuncture and medicine .
0
176,011
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25876339
2methods
One hundred and forty-one patients were randomized into an acupuncture group ( @ cases ) and a medicine group ( @ cases ) .
1
176,012
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25876339
2methods
In the acupuncture group , the needling technique for benefiting qi , promoting blood circulation , regulating mind and improving intelligence was used at Shenting ( GV @ ) , Baihui ( GV @ ) , Fengchi ( GB @ ) , Wangu ( GB @ ) , Danzhong ( CV @ ) , Zhangwan ( CV @ ) , Qihai ( CV @ ) , Xuehai ( SP @ ) and Zusanli ( ST @ ) .
2
176,013
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25876339
2methods
The supplementary acupoints were selected according to the symptoms and physical signs .
3
176,014
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25876339
2methods
Acupuncture was given once a day and @ treatments were required for a week .
4
176,015
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25876339
2methods
In the medicine group , the choline sterase inhibitor , donepezil ( aricept ) was prescribed for oral administration , @ tablet ( @ mg ) each time , once every night .
5
176,016
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25876339
2methods
Four weeks later , the dose was increased to @ tablets ( @ mg ) each time .
6
176,017
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25876339
2methods
In the two groups , the treatment of @ weeks made one session and @ sessions were required .
7
176,018
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25876339
2methods
The changes of scores before and after treatment in the minimum mental state examination ( MMSE ) , the activity of daily living scale ( ADL ) , Alzheimer 's disease assessment scale-cognition ( ADAS-cog ) and the digit span ( DS ) were observed .
8
176,019
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25876339
4results
After treatment , scores of MMSE and DS were increased as compared with those before treatment ( both P < @ ) and scores of ADL and ADAS-cog were reduced as compared with those before treatment .
9
176,020
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25876339
4results
The score differences in MMSE , ADL , ADAS-cog and DS before and after treatment were significant in the two groups ( all P < @ ) .
10
176,021
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25876339
1conclusions
The needling technique for benefiting qi , promoting blood circulation , regulating mind and improving intelligence significantly improves the overall function , cognition and activity of daily life in the patients of Alzheimer 's disease and the efficacy is better than donepezil .
11
176,022
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24946799
3objective
There is little evidence available on the use of robot-assisted therapy in subacute stroke patients .
0
176,023
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24946799
3objective
A randomized controlled trial was carried out to evaluate the short-time efficacy of intensive robot-assisted therapy compared to usual physical therapy performed in the early phase after stroke onset .
1
176,024
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24946799
2methods
Fifty-three subacute stroke patients at their first-ever stroke were enrolled @days after the acute event and randomized into two groups , both exposed to standard therapy .
2
176,025
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24946799
2methods
Additional @ sessions of robot-assisted therapy were provided to the Experimental Group .
3
176,026
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24946799
2methods
Additional @ sessions of usual therapy were provided to the Control Group.The following impairment evaluations were performed at the beginning ( T@ ) , after @ sessions ( T@ ) , and at the end of the treatment ( T@ ) : Fugl-Meyer Assessment Scale ( FM ) , Modified Ashworth Scale-Shoulder ( MAS-S ) , Modified Ashworth Scale-Elbow ( MAS-E ) , Total Passive Range of Motion-Shoulder/Elbow ( pROM ) , and Motricity Index ( MI ) .
4
176,027
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24946799
4results
Evidence of significant improvements in MAS-S ( p = @ ) , MAS-E ( p = @ ) and pROM ( p < @ ) was found in the Experimental Group .
5
176,028
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24946799
4results
Significant improvement was demonstrated in both Experimental and Control Group in FM ( EG : p < @ , CG : p < @ ) and MI ( EG : p < @ , CG : p < @ ) , with an higher improvement in the Experimental Group .
6
176,029
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24946799
1conclusions
Robot-assisted upper limb rehabilitation treatment can contribute to increasing motor recovery in subacute stroke patients .
7
176,030
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24946799
1conclusions
Focusing on the early phase of stroke recovery has a high potential impact in clinical practice .
8
176,031
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24668328
0background
In advanced gastric cancer ( AGC ) , no globally accepted prognostic scoring system has been developed .
0
176,032
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24668328
0background
Therefore , we explored baseline prognostic factors in Japanese AGC patients using the data from a randomized controlled trial , Japan Clinical Oncology Group ( JCOG ) @ , which investigated the efficacy of systemic chemotherapy as a first-line treatment .
1
176,033
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24668328
2methods
Prognostic factors and prognostic indices for overall survival were screened and evaluated in patients enrolled in JCOG@ using the Cox proportional hazard model .
2
176,034
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24668328
2methods
The Royal Marsden Hospital prognostic model was also applied to the JCOG@ trial .
3
176,035
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24668328
4results
A total of @ ( @ % ) of the @ patients randomized in the JCOG@ trial , for whom complete data were available for multivariate analyses , was included in the present study ( @-fluorouracil arm , n = @ ; irinotecan plus cisplatin arm , n = @ ; S-@ arm , n = @ ) .
4
176,036
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24668328
4results
The median survival time ( MST ) for all patients was @ months .
5
176,037
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24668328
4results
To construct a prognostic index , we selected four risk factors by multivariate analysis : performance status @ , number of metastatic sites @ , no prior gastrectomy , and elevated alkaline phosphatase .
6
176,038
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24668328
4results
MSTs were @ months for patients categorized into the low-risk group , who had zero or one risk factor ( n = @ ) ; @ months for patients in the moderate-risk group , who had two or three risk factors ( n = @ ) ; and @ months for patients in the high-risk group , who had all four risk factors ( n = @ ) .
7
176,039
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24668328
1conclusions
In the present study , we propose a new prognostic index for patients with AGC .
8
176,040
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24668328
1conclusions
This can be used for more appropriate patient stratification in future clinical trials .
9
176,041
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24834773
0background
Treatment of food allergy essentially consists of food avoidance , but immunotherapy with food is emerging as a new therapeutic option .
0
176,042
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24834773
3objective
To evaluate clinical improvement and immunological changes in patients with peach allergy following sublingual immunotherapy ( SLIT ) with a Prup@ quantified peach extract .
1
176,043
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24834773
2methods
A randomized , double-blind , placebo-controlled clinical trial with peach SLIT was conducted .
2
176,044
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24834773
2methods
We assessed clinical efficacy after @ months of treatment by means of double-blind , placebo-controlled oral challenges with peach and also evaluated immunological changes ( basophil activation test -LSB- BAT -RSB- and determination of sulphidoleukotriene production ) following stimulation with peach peel and pulp , rPrup@ , rMald @ , and rMal d @ stimulation .
3
176,045
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24834773
2methods
We also measured specific IgE and IgG@ to Pru p@ .
4
176,046
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24834773
4results
After @ months of SLIT ( T@ ) , the active group showed a @-fold improvement in tolerance to Prup@ and a significant increase in IgE to rPrup@ and in sLT production following stimulation with peach peel and rPrup@ .
5
176,047
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24834773
4results
There was also a significant increase in BAT results after stimulation with rPrup@ at @ month of SLIT ( T@ ) .
6
176,048
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24834773
4results
Statistically significant between-group differences were only observed for BAT with peach peel and pulp at T@ and T@ and for BAT with rPru p@ at T@ .
7
176,049
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24834773
4results
No changes were observed in BAT with rMal d @ or rMal d @ or in IgG@ levels to nPrup@ .
8
176,050
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24834773
1conclusions
SLIT with a Pru p @ quantified peach extract is clinically effective and leads to an increase in basophil activation and sulphidoleukotriene production following stimulation with rPru p@ and peach peel in the first months of treatment .
9
176,051
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24777223
3objective
Pharmacogenetics ( PGx ) promises to optimize patient response to therapy .
0
176,052
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24777223
3objective
However , the public 's acceptance of PGx is not well known , notably when this applies to children .
1
176,053
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24777223
3objective
Our objective was to explore perceptions of PGx testing among individuals , who differ from each other by either parental status or educational exposure to PGx , and to explore parents ' views between PGx testing for oneself and PGx testing for their children .
2
176,054
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24777223
2methods
An exploratory survey was conducted among parents and other adults .
3
176,055
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24777223
2methods
Surveys P and C were completed by parents , survey NP by middle-aged nonparents , and survey MS by medical students .
4
176,056
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24777223
4results
Proper explanation before PGx testing appeared to be the most important issue to the respondents ( eg , P = @ @ ( -@ ) for survey NP ) .
5
176,057
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24777223
4results
Respondents who were more knowledgeable about PGx were also more comfortable with PGx testing ( eg , P = @ @ ( -@ ) in case of mild disease ) .
6
176,058
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24777223
4results
When PGx testing was for one 's child , parents valued their own understanding more than their child 's assent ( P = @ @ ( -@ ) ) .
7
176,059
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24777223
1conclusions
The acceptability of PGx testing , either for oneself or for one 's child , seemed to depend on baseline PGx knowledge , but not on parenthood .
8
176,060
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24320560
3objective
Dilatation and curettage ( D&C ) is a common day-care procedure in obstetrics and gynecology , with patients discharged after a brief hospital stay on the same day of the surgery .
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24320560
3objective
Although it has a short duration , severe pain occurs during the procedure .
1
176,062
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24320560
3objective
Therefore , this surgical procedure requires an anesthetic to provide adequate analgesia , rapid onset , and rapid recovery .
2
176,063
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24320560
3objective
The main objective of the present study was to compare the analgesic effectiveness and safety of tramadol with those of fentanyl during D&C .
3
176,064
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24320560
2methods
The study comprised @ women with American Society of Anesthesiologists classification I-II who were scheduled for a D&C procedure .
4
176,065
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24320560
2methods
Baseline anesthesia was maintained with @mg/kg propofol , and the patients were then randomly allocated to receive tramadol @mg/kg ( Group T , n = @ ) or fentanyl @g/kg ( Group F , n = @ ) .
5
176,066
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24320560
2methods
Hemodynamic variables , sedation , pain , the Aldrete recovery score , and side-effects were recorded .
6
176,067
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24320560
4results
SpO levels in Group F in the @th min and at the end of the procedure were significantly lower than those in Group T ( P = @ and @ , respectively ) .
7
176,068
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24320560
1conclusions
Tramadol provides similar analgesic efficacy to fentanyl .
8
176,069
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24320560
1conclusions
Furthermore , tramadol may provide better respiratory stability in patients undergoing a D&C procedure .
9
176,070
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26483244
0background
Based on current recommendations , @ + pack-years of smoking are required for eligibility for low-dose CT ( LDCT ) lung cancer screening ; former smokers must have quit within @ years .
0
176,071
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26483244
0background
We investigated whether current smokers with @ to @ pack-years have similar lung cancer risks as eligible former smokers and also whether they have a different demographic profile .
1
176,072
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26483244
2methods
The Prostate , Lung , Colorectal , and Ovarian Cancer Screening Trial ( PLCO ) was a randomly assigned screening trial of subjects age @ to @ years with chest radiographs ( CXR ) used for lung cancer .
2
176,073
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26483244
2methods
Subjects completed a baseline questionnaire containing smoking history questions .
3
176,074
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26483244
2methods
Cox proportional hazards models , adjusted for age and sex , were utilized to estimate hazard ratios ( HRs ) for various smoking history groups .
4
176,075
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26483244
2methods
Next , we utilized the National Health Interview Survey ( NHIS ) , which inquired about smoking history and race/ethnicity , to analyze the demographic profiles of various high-risk smoking history categories .
5
176,076
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26483244
2methods
All statistical tests were two-sided .
6
176,077
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26483244
4results
The PLCO cohort included @ @ former and @ @ current LDCT-eligible smokers , plus @ @ - to @-pack-year current smokers .
7
176,078
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26483244
4results
The hazard ratio for @ - to @-pack-year current smokers compared with eligible ( @ + pack-year ) former smokers was @ ( @ % confidence interval -LSB- CI -RSB- = @ to @ ) .
8
176,079
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26483244
4results
Based on the NHIS , @ million persons in the United States are currently LDCT eligible ; an additional @ million ( @ % , @ % CI = @ % to @ % ) are @ - to @-pack-year current smokers .
9
176,080
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26483244
4results
The percentage increase in eligibles if @ - to @-pack-year current smokers were included was substantially greater for women than men ( @ % , @ % CI = @ % to @ % ; vs @ % , @ % CI = @ % to @ % , P < @ ) and for minorities than non-Hispanic whites ( @ % , @ % CI = @ % to @ % ; vs @ % , @ % CI = @ % to @ % , P < @ ) .
10
176,081
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26483244
1conclusions
The potential benefits and harms of recommending LDCT screening for @ to @-pack-year current smokers should be assessed .
11
176,082
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25624432
3objective
Progression-free survival ( PFS ) in metastatic castration-resistant prostate cancer ( mCRPC ) trials has been inconsistently defined and poorly associated with overall survival ( OS ) .
0
176,083
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25624432
3objective
A reproducible quantitative definition of radiographic PFS ( rPFS ) was tested for association with a coprimary end point of OS in a randomized trial of abiraterone in patients with mCRPC .
1
176,084
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25624432
2methods
rPFS was defined as two new lesions on an @-week bone scan plus two additional lesions on a confirmatory scan , two new confirmed lesions on any scan @ weeks after random assignment , and/or progression in nodes or viscera on cross-sectional imaging , or death .
2
176,085
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25624432
2methods
rPFS was assessed by independent review at @ % of deaths and by investigator review at @ % and @ % of deaths .
3
176,086
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25624432
2methods
rPFS and OS association was evaluated by Spearman 's correlation .
4
176,087
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25624432
4results
A total of @,@ patients were randomly assigned to abiraterone plus prednisone or prednisone alone .
5
176,088
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25624432
4results
At first interim analysis , the hazard ratio ( HR ) by independent review was @ ( @ % CI , @ to @ ; P < @ ; abiraterone plus prednisone : median rPFS , not estimable ; prednisone : median rPFS , @ months ) .
6
176,089
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25624432
4results
Similar HRs were obtained by investigator review at the first two interim analyses ( HR , @ ; @ % CI , @ to @ ; P < @ and HR , @ ; @ % CI , @ to @ ; P < @ , respectively ) , validating the imaging data assay used .
7
176,090
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25624432
4results
Spearman 's correlation coefficient between rPFS and OS was @ .
8
176,091
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25624432
1conclusions
rPFS was highly consistent and highly associated with OS , providing initial prospective evidence on further developing rPFS as an intermediate end point in mCRPC trials .
9
176,092
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24990004
0background
Rehabilitation care is an important part of comprehensive care for MS patients .
0
176,093
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24990004
0background
Little is known about the number of physiatry residents who are interested in providing care to individuals with multiple sclerosis -LSB- MS -RSB- .
1
176,094
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24990004
3objective
This study examines factors that influence physiatry residents ' interest in providing care to MS patients .
2
176,095
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24990004
2methods
We randomly sampled half of all Accreditation Council for Graduate Medical Education-certified physical medicine and rehabilitation residency programs in the continental United States and Puerto Rico .
3
176,096
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24990004
2methods
Surveys were received from @ % of programs ( Stage @ response rate ) and from @ residents ( @ % Stage @ response rate ) .
4
176,097
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24990004
4results
Residents expressing interest in providing MS care were more likely to be female , Asian , and to select statements emphasizing multidisciplinary care approaches and a community of dedicated professional colleagues as positive features of MS patient care .
5
176,098
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24990004
4results
Residents interested in teaching and with more education debt were marginally more likely to express interest in MS care .
6
176,099
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