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Method.

A descriptive cross-sectional study with the participation of 70 mothers whose children were treated at the Intensive Care Unit, Children's Hospital 1, from May 2022 to August 2022.

Data were collected using a self-completed questionnaire.

The average stress level of mothers in this study was 1.11 (SD± 0.32).

The change in motherhood / duty was the most stressful factor with a mean stress level of 3.75 (SD±0.96).

There is a correlation between the level of social support and the stress of mothers.

There was no correlation between the mother's stress level and the mother's age, the mother's education and income, and the child's age and number of hospital admissions.

Job satisfaction among staff working at Kien Giang Center for disease control and prevention and some associated factors, 2021

To provide more evidence on the safety profile of dapagliflozin (ForxigaTM) in real-life settings, eight hospitals across Vietnam were involved to implement a post marketing surveillance program.

Among 1001 subjects, 278 patients (27.8%) experienced at least 1 adverse event (AE) during 24 weeks of follow-up, 5 of those (0, 5%) were serious adverse events (SAEs) and 29 (2.9%) led to modification of dapagliflozin treatment.

Arthritis (2.4%) and hepatic enzyme increased (2.4%) were the most common, followed by urinary tract infection (1.9%).

However, only 120 (12.0%) AEs were evaluated as dapagliflozin-related adverse events.

The results revealed that dapagliflozin was well tolerated in Vietnamese adult patients with type 2 diabetes mellitus.

Besides the databases of spontaneous ADR reports, this study provides additional data and did not find any new or significant risks of dapagliflozin (Forxiga), supporting its safety profile for the future users in Vietnam.

Status of medical examination and health care management of the elderly in 2 communes of Trieu Son district, Thanh Hoa province in 2017

From January to June 2017, we studied status of medical examination in the elderly and health worker and heath care worker in 2 communes of Trieu Son district, Thanh Hoa province, we obtained results: The proportion of the elderly selected the district hospital for the highest level of health care (45.6%), That of medical station was 39, 9%, that of central hospital was 0, 1%.

The percentage of senior people who have health insurance is 76, 5%, of which The percentage of the elderly with voluntary insurance is 15.9% and health insurance policy was 84.1%.

The percentage of the elderly who regular checkup was 14, 1%

Results of endovascular mechanical thrombectomy within 6 to 24 hours in eligible acute ischemic stroke patients

A cross-sectional study was conducted on 200 staff working at Kien Giang Center for Disease Control and Prevention from 01/2021 to 06/2021 to assess their satisfaction with their job and identify some associated factors.

Results of the study showed that all of the percentages of satisfaction of staff with different aspects of their job were high (>75%).

The percentage of satisfaction with of coworker relationships was the highest (86%) and the percentage of satisfaction with the management mechanism was the lowest (75.5%).

The percentage of staff's overall satisfaction (satisfaction with all factors) was 76.5%.

Some associated factors with staff's satisfaction were sex, seniority and type of work (p<0, 05).

Results of treatment ductal carcinoma in situ of breast cancer at K hospital

To evaluate the safety and efficacy of mechanical thrombectomy in patients with anterior circulation stroke who were treated 6 to 24 hours after they were last known to be well.

Subject and methods: We conducted a prospective study of consecutive acute ischemic stroke patients who underwent endovascular treatment 6 to 24 hours after last seen well.

All patients had confirmed proximal middle cerebral artery or internal carotid artery occlusion by CTA or MRA, and met the mismatch criteria of DAWN or DEFUSE-3 trial.

The primary outcome was the functional disability at day 90, as measured on the modified Rankin scale (mRS).

Results: A total of 80 patients were enrolled between January 2021 and May 2021 in 115 People's Hospital.

At 90 days, the rate of functional independent (mRS score of 0 to 2) was 51, 2%, and mortality rate was 12, 5%.

Successful recanalization (TICI score of 2b or 3) was 96, 2%.

Symptomatic intracranial hemorrhage was reported in four patients (5%).

Conclusions: The safety and efficacy of extended window thrombectomy in late-arriving patients with target mismatch profile supports a practical use of endovascular therapy in this patient population in Vietnam.

Photobiomodulation therapy and antiviral photodynamic therapy as potential treatment modalities for COVID-19

Conclusion: Treatment of ductal carcinoma in situ of breast cancer including surgery, radiotherapy, and endocrine therapy provides good results, low surgical complications, and requires long-term follow-up to evaluate recurrence and metastasis.

Tumour size ≤25 mm accounts for 83.3%.

Intermediate-grade DCIS accounted for 52.6%; the percentage of estrogen receptor-positive was 55.1%.

The mastectomy and breast-conservingsurgery rateswere 83.3% and 16.7%, respectively.

Complications were found in 10.2%.

The proportion of patients receiving endocrine therapy was 55.1%, and adjuvant radiation therapy was 15.4%.

No recurrence and metastasis.

Treatment of the of adjustment disorders with brief depressive reaction

COVID-19 disease is a dangerous infectious disease caused by the SARS-CoV-2 virus and is currently a pandemic in the world and in Vietnam.

In this disease control strategy, the role of treatment when infected is very important.

Antiviral photodynamic and photobiomodulatory therapy is a new therapeutic direction in the treatment of COVID-19 patients.

The treatment direction which combines photobiomodulation and antiviral photodynamics with conventional drug administration reveals high potential as well as great helpful promise of new methods in the treatment of COVID-19 patients.

Primary outcomes of single-stage biventricular repair for aortic arch obstruction-ventricular septal defect with left ventricular outflow tract obstruction at National children’s hospital

The study aims to describe treatment of adjustment disorder with brief depressive reaction.

This was a cross-sectional study observing treatment of 66 patients at the National Institute of Mental Health, Bach Mai hospital. All of them were diagnosed with adjustment disorder with brief depressive reaction (F43.20) that required hospitalization.

The results showed that among the antidepressants were used for treatment, Amitriptylin was the most common medication with the starting dose was 40.3 ± 23.9 mg / day and the highest dose was 75, 0 ± 35.4 mg / day.

Followed by Remeron with the starting dose was 30.0 ± 13.6 mg / day and the maximum dose was 47.6 ± 14.8.

The most common adverse effect of antidepressants was dry mouth (62.1%).

Clinical effect of bioceramic sealers: scoping review

Evaluation of the early results of single-stage biventricular repair, which includes aortic arch reconstruction, ventricular septal defect closure and release of the left ventricular outflow tract obstruction.

There were 2 early deaths (4.7%) and 1 late death (2.3%), and the overall mortality was 7%.

There were 2 patients (5%) who required reoperation due to recurrent left ventricular outflow tract obstruction during follow-up, and 1 patient (2.5%) need balloon angioplasty for aortic valve stenosis during the follow-up time of 1.5 years (IQR, 0.6 - 4).

The overall survival and the survival without reoperation at 7-year were 88.5% and 88.5%, respectively.

Methods: From December 2013 to October 2020, all patients diagnosed with aortic arch obstruction, ventricular septal defect and left ventricular outflow tract obstruction who underwent single-stage biventricular repair were retrospectively studied.

Results: There were 43 patients who underwent single-stage repair combined with left ventricular outflow tract obstruction release.

The median age at operation was 37 days (IQR, 22 - 62), and median weight was 3.7 kg (IQR, 3.2 - 4.1).

There were 29 males (67.4%) and 14 females.

The mean time of aortic cross-clamp time was 98.7  26.3 minutes, the mean time of bypass was 135.6  41.5 minutes, and the mean time of regional cerebral perfusion was 32  11.2 minutes.

There were 18 patients (41.9%) who underwent conal septum resection, and 25 patients who underwent placement of the superior border of the ventricular septal defect patch to the left side of the conal septum, in order to release the left ventricular outflow tract obstruction.

No patient suffered from aortic valve injury or complete atrioventricular block requiring permanent pacemaker implantation.

Two patients required extracorporeal oxygenation membrane support postoperative.

Assessment of the albumin-bilirubin (ALBI) grade for hepatocellular carcinoma patients with cirrhosis

Results: out of 885 articles found on the databases, 22 articles were found that matched the research criteria.

A total of 1629 teeth from patients with ages ranging from 18 to 65.

The results showed that there is not significant difference between Bioceramic and traditional sealer (AH plus, sealer based on eugenol ZnO) in pain level, pain frequency after filling of 24 hours, 48 hours, 72 hours.

Moreover, there is not significant difference among sealers in studies regarding healing apical.

Conclusion: Under limit of this research, it showed that Bioceramic Sealers have optimal efficiency, result same with other sealers regarding average pain level after filling, danger arising and pain intensity at 24 hours and 48 hours.

The finding in studies is to provide information on clinical evaluation of Bioceramic sealer.

Construct the model of cost– effectiveness analysis of Daratumumab versus standard therapy in the treatment of multiple myeloma in Vietnam

Hepatocellular carcinoma (HCC) in patients with cirrhosis frequently reported.

We evaluated the usefulness of albumin-bilirubin (ALBI) grade as a tool for assessment of hepatic reserve function.

Subjects and methods: We enrolled 224 HCC patients from 2018 - 2019. Child-Pugh classification and ALBI grading were calculated.

Results: A total of 224 HCC patients (186 males and 38 females, age range, 28 - 90 years, average age, 59 years) were valuated ALBI.

According to BCLC classification, BCLC stage A (20.2%), BCLC stage B (45.7%), and BCLC stage C (23.8%) and stages D (10.3%).

Child-Pugh clasifications and ALBI-based BCLC systems were highly concordant.

Conclusions: the albumin-bilirubin (ALBI) grade, as a prognosticator has demontrated that was correlated with Child-pugh clasification and BCLC stages in HCC patients.

Enhance accuracy of tumor classification from gene expression of microarray

Daratumumab was approved by the Food and Drug Administration (FDA) in 2015 in the treatment of multiple myeloma [3] and its clinical efficacy has been confirmed through many studies around the world [6].

However, cost-effectiveness is a factor to consider when prescribing drugs in clinical practice, especially in countries with limited health budgets like Vietnam.

In cost-effectiveness analysis, model building is an important step, especially since no research has been conducted in Vietnam.

With the modeling method, the cost - effectiveness analysis model has been built based on Microsoft Excel 2013 software with model structure.

The model allows evaluating the cost - effectiveness of daratumumab versus standard therapy in treating multiple myeloma in Vietnam.

Food safety and factors affecting food safety in our country

Gene expression microarray data is one of the most popular for dianosis of cancer.

However, the microarray data have thousands of genes and very few samples, it is crucial to develop techniques to effectively gene selection for analysis.

So, dimension reduction is an important issue for analysis, of which principle component analysis (PCA) is one of the frequently used methods, and in the previous works, the top several principle components are selected for modeling according to the descending order of eigenvalues.

While in this paper, we argue that not all the first features are useful, but features should be selected form all the components by feature selection methods.

As a case study, we have considered PCA for dimension reduction, decesion tree algorithms (DT) for feature selection, and then Multi Layer Perceptron network (MLP) for classification.

Experimental results illustrate that our proposed framework is effective to enhance classification accuracy rates.

Results of laparoscopic treatment for postoperative adhesive bowel obstruction in Can Tho central general hospital

Laparoscopic surgery is a less invasive method and able to decreases the risks of postoperative adhesive forming.

Therefore, we carry out this research to assess the roles of laparoscopic treatment for postoperative adhesive bowel obstruction.

Objectives: to assess the results and relative factors of laparoscopic surgery for postoperative adhesive bowel obstruction treatment in Can Tho Central General Hospital.

Method anh subjects: from March 2016 to June 2018, we reviewed 50 patients with postoperative adhesive obstruction in a retropective research.

Results: among 50 patients (male / female = 1, 5) postoperative adhesive bowel obstruction, the successful ratio of laparoscopic adhesiolysis was 84%; the fourth trocar was needed in 16%; 54% of cases was due to single band, 80% of patients was treated by pure laparoscopic, 6% needed open a small <5 cm incision, 14% had to convert to open surgery, the mean time surgery in the pure laparoscopic group was 82, 38 min; intraoperative complications included intestinal serosa tear (10%), bowel perforation (6%); the main etiologic agent of conversion was deep adhesion (10%); postoperative complications included septic shock (2%), hospital pneumonia (2%).