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Hi, My doctor recently put me on Klor-Con M20 (40 MEQ) per day. After my blood tests, my doctor was alarmed with the results (very high calcium and very low Magnesium, Potassium, and other electrolytes). She asked if I had an eating disorder....I don t, but was very worried when she asked such a question. Why would she ask this, and what is the Klor-Con for?
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I have been having chest pains in the middle of chest for about a week that come and go. It is different from when I had them with anxiety a few years ago. This time it would spread to face some and down right arm specifically. Today I turned to look out car window and my chest had gripping pain in the middle that took my breath. Tonight I have a lot of pressure in the center. I do have gerd controlled by 150 mg zantac am and pm
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INTRODUCTION: Gendered differences in career paths of medical graduates persist globally. We aim to explore the impact of domestic tethers on the career paths of physicians by studying gendered differences in domestic burdens of physicians as well as differences in perceptions around the impact of domestic work on professional advancement. METHODS: A web-based survey including 38 questions was sent to all 3866 physician alumni of the top academic medical school in Lebanon. Data was collected between November 2018 and January 2019, with up to three invite reminders. Overall, 382 were included in the final analysis, 124 women (32%), 258 men (68%). RESULTS: The study had a response rate of 10.4%. Findings show that a greater percentage of men were married and had children (77.5% vs 62.1%, p = 0.004, 77.9% vs 51.6%, <0.001, respectively). Majority of both women and men held full-time positions (82.1% and 87.1%), having children however reduced the odds significantly [OR = 0.2, 95% CI: (0.1–0.6), p = 0.01]for women, while only older age reduced it for men (OR = 0.1,95% CI: (0.04–0.2), p<0.001]. Among full-time physicians, men and women spent similar time on professional activities (60.2hrs/wk vs 58.3hrs/wk, p = 0.32). Women spent more time on parenting and household work (23.5hrs/wk vs 10.4hrs/wk, <0.001; 8.9hrs/wk vs 6.0hrs/wk, p = 0.001, respectively). Women physicians’ spouses contributed to 14.5 hours/week of total time on domestic activities whereas men physicians’ spouses spent two folds more time on domestic activities (35.0 hours/week, P<0.001). Of physicians with children, a higher percentage of women than men reported that children prevented their career advancement or their participation in development opportunities (43.8% vs 15.9%, p<0.001; 50.0% vs 19.4%, p<0.001, respectively). A greater percentage of women than men scaled back their career after first child (31.3% vs 3.5%, <0.001). Of married/partnered physicians, fewer women than men reported their career took priority over their partner’s when conflicts arose, (52.0% vs 86.0%, p<0.001). CONCLUSION: These findings highlight the heavier impact of domestic tethers on the career paths of women physicians than men physicians. Men are more likely than women to hold full-time positions in the early advancement defining phases of their careers. Full-time women shoulder more domestic work than men and experience more professional advancement concessions. Closing persistent gender gaps in medicine requires addressing inequities in domestic burdens through strategies that include mentorship on domestic tethers, support of on-site child-care and advocacy for parental leave policies that encourage shared care-work.
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My 4 year old has a small movable (pea sized) lump under her armpit. When I first noticed it about a month ago, her doctor said there was nothing to worry about. It is still here and it feels a little bigger and she now says it is sore. What could this be?
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Hi, may I answer your health queries? Please type your query here... hi I AM Rafiq Mansoori I have a Porblem My Semen comes out whil toilet pls Suggest is it Harmful for me ? even i have a sexual life problem wirth my wife while for play with wife semen comes out before getting interact with wife through my penis pls kindlky suggest
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Dr ITP was diagnoized during a hospital treatment for dengu fever in 2007. Took Wyslone and omnacartil, which led to fatigue. Now the body has adapted low platelet counts. No abnormality in Bone marrow test. Whenever infected with viral infection, the count comes to precariously low level. What further treatment can be suggested?
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Dear Doctor, My wife give birth to a boy baby, My son is about 14 days old, Only one one drop comes from my wife breast when she press it. when she press her niple the drop of milk comes out and my baby suck it but when drop of milk outing stop than my son did not suck the breast and start crying. Doctor advise us to start Lactogen 1 and we start it now. Dear Doctor please advise me with a humble suggestion. we are very confuse what we can do now, that my baby start sucking breast.
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Hi i suffer with anxiety and depression i feel dizzy unbalanced and strange all the time sometimes when i walk its like the floor is moving up and down i also fear of passing out im having burning sensations in my right here and have odd feelings in the right side of my head and have the odd pains but it only seems to be in the right side of my head could someone please confirm this is anxiety and not another illness
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What are cholinergic receptors, and where are they found in the body?
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my 10 year old wakes each morning to sneezing and a bleeding nose. I have washed out nasal passages before bed as well as coating with olive oil. He also breaths thru his mouth verses his nose while he sleep. No Fever, mucus is clear once nose stops bleeding, eys burn and ears sometimes itch.
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Hi...I have suffered from anemia for about 2 years now..my symptoms have now worsened.I have constant dizziness,pain in my head, I have shortness of breathe when I talk,eat and even sit still. I feel very tired.i am blue around my lips on occasions and other people notice when I feel worse. I have fibromyalgia,chronic pain and fatigue syndrome
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I know I have chronic lower back pain. It's in the lower center of back my. I have had numerous injections and nerve blocks, nothing works. I cannot stand longer than 5 or 10 minutes without going into a terrible sweat and the chronic pain starts. When I sit the pain goes away, however, I still have a numbing, throbbing pain that stays with me continually sitting. I was referred to a Rheumatologist who told me my SED level was 79, he put me on meds that did not touch the pain and I'm even more miserable than I've ever been in my life. The Rheumatologist has changed my meds at least 3 times and I still am getting no relief. HELP. Have I been diagnosed wrong. What is wrong with me. This pain came over a period of time and has gradually has increased. Did I mention I have a small disc, but every doctor seems to think that the source of my back pain could not be related to that tiny disc. What should I do. I need relief. I want to walk without being in pain and I'm young with a child.
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1 yr old female, on blood thin r 2 yrs from a clot in leg, have Lupas, not active, underarms and out about 5 inches toward elbow and inside top of thighs up around to my hips dark skin looks somewhat like buise. On a trip to see mom for mothers day... also on a anti depresant... do I go see vien Doc or Lupas Doc or Reg Doc when I get home on Tues?
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I hurt in my lower left pelvic area for four years before finally being diagnosed with a 2 cm kidney stone. (had exploratory surgery as well as partial and final hysterectomy , colonoscopy , etc before finally the kidney stone was found. ) Dr. Initially thought pain was not matching up with kidney stones because i hurt in my lower left pelvic area and not in the upper area where kidney stone was at. Dr blasted then removed via basket. Left a ureter stint with string for a week which was removed today. Now I am having extreme pain in that same lower pelvic area. could this be renal colic or my ureter or???????
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Hi I was home alone something outside the window startled me so I looked out of the window and the next thing I knew I was waking up on the floor in a cold sweat....felt like I had to vomit ...weak ....hands shaking ....blurred vision and ears ringing ....what could be wrong ???
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Hello doctor,I have a few concerns, got a few lines appearing on my nail, which is dark vertical stripes. Especially the one on my right thumb is in the middle, and it has been here for the last two weeks now.
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my grandson just went to the doctors from his knee down have turned purple the doc sent him for exrays haven t herd anything yet for the results but our doc said it was a lack of oxygen to his leg what would cause this he is seventeen years of age im worried
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Tried to begin weaning 6 month old baby on Cerelac stage 1; 30ml water+1 tablespoon Cerelac; fed 2-3 teaspoons; followed by his usual 120 ml milk feed; baby vomitted out everything after 1-2 hours, and has been belching ever since, even though his stomach is now completely empty
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Hi I was wondering if you could help me diagnose my symptoms!? I rang my docs Friday but they had no appointments for a week!! I have had a sharp pain across my centre head from ear to ear I have taken paracetamol but doesn t help, I have a dull achy pain in both ears, a sore throat and a bit of a cough , nausea , tired, my eyes have been sore dry and itchy and pain in my chest and shortness breath sometimes but I do have asthma using blue Inhailer. I have had these symptoms for a week now! Can you help me? Thank you
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I had bladder cancer and they did surgery to remove cancer. I am now at 4 months post surgery. I went to the urologist today for my 3 month check up (cisto). There is either a hole or a pocket as the Dr. said at the surgery site. She would not give me any more info than that she wants me to have an xray with a balloon catheder. Should would not speculate or even answer any of our questions like where is the urine going if it is a hole, or what would the procedure be if it is a hole. I m not feeling to confident with this Dr. that did the original surgery. I am worried. I have returned to work 2 weeks ago. I get tired and have some pain but I manage. After my surgery I was constipated and developed a fissure in my rectum and my sciatic nerve flared up to the point I couldn t walk. I am still taking stuff ( mag citrate) to keep my bowels loose and a probiotic.
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Son has swollen knuckles middle joint, seems to. Ache a lot. Nothing terribly serious but after an activity, he wears out quicker than most and complains of minor joint pain in his ankles a arms. Tonight he said he has some shaking in his hands. He has Aspergers so I know he gets anxious but don t want to miss something. Also he has stretch marks from rapid growth spurts. Any direction I should look into? Thank you
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Hi, If I masturbate by rubbing my hand on inner skin of my penis, then after a while it starts paining if I pull my outer skin of the penis. If I cover my penis with outer skin then it will stop paining. But then I cant masturbate properly as I cant pull my outer skin. What could be the reason. Pl. help.
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Pulmonary Hypertension (Types): The World Health Organization divides pulmonary hypertension (PH) into five groups. These groups are organized based on the cause of the condition. In all groups, the average pressure in the pulmonary arteries is higher than 25 mmHg at rest or 30 mmHg during physical activity. The pressure in normal pulmonary arteries is 8–20 mmHg at rest. (Note that group 1 is called pulmonary arterial hypertension (PAH) and groups 2 through 5 are called pulmonary hypertension. However, together all groups are called pulmonary hypertension.) Group 1 Pulmonary Arterial Hypertension Group 1 PAH includes: PAH that has no known cause. PAH that's inherited (passed from parents to children through genes). PAH that's caused by drugs or toxins, such as street drugs and certain diet medicines. PAH that's caused by conditions such as: - Connective tissue diseases. (Connective tissue helps support all parts of your body, including your skin, eyes, and heart.) - HIV infection. - Liver disease. - Congenital heart disease. This is heart disease that's present at birth. - Sickle cell disease. - Schistosomiasis (SKIS-toe-so-MI-ah-sis). This is an infection caused by a parasite. Schistosomiasis is one of the most common causes of PAH in many parts of the world. Connective tissue diseases. (Connective tissue helps support all parts of your body, including your skin, eyes, and heart.) HIV infection. Liver disease. Congenital heart disease. This is heart disease that's present at birth. Sickle cell disease. Schistosomiasis (SKIS-toe-so-MI-ah-sis). This is an infection caused by a parasite. Schistosomiasis is one of the most common causes of PAH in many parts of the world. PAH that's caused by conditions that affect the veins and small blood vessels of the lungs. Group 2 Pulmonary Hypertension Group 2 includes PH with left heart disease. Conditions that affect the left side of the heart, such as mitral valve disease or long-term high blood pressure, can cause left heart disease and PH. Left heart disease is likely the most common cause of PH. Group 3 Pulmonary Hypertension Group 3 includes PH associated with lung diseases, such as COPD (chronic obstructive pulmonary disease) and interstitial (IN-ter-STISH-al) lung diseases. Interstitial lung diseases cause scarring of the lung tissue. Group 3 also includes PH associated with sleep-related breathing disorders, such as sleep apnea. Group 4 Pulmonary Hypertension Group 4 includes PH caused by blood clots in the lungs or blood clotting disorders. Group 5 Pulmonary Hypertension Group 5 includes PH caused by various other diseases or conditions. Examples include: Blood disorders, such as polycythemia vera (POL-e-si-THE-me-ah VAY-rah or VE-rah) and essential thrombocythemia (THROM-bo-si-THE-me-ah). Systemic disorders, such as sarcoidosis (sar-koy-DO-sis) and vasculitis (vas-kyu-LI-tis). Systemic disorders involve many of the body's organs. Metabolic disorders, such as thyroid disease and glycogen storage disease. (In glycogen storage disease, the body's cells don't use a form of glucose (sugar) properly.) Other conditions, such as tumors that press on the pulmonary arteries and kidney disease.
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I m having problems with my blood pressure, it used to be high then I had one of my adrenal gland removed and the blood pressure went down almost too low, I haven t been taking any medication for a yr now. It s going up and down, yesterday it was 124/77 today is 149/92. What could be causing it?
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I HAVE CHECKED BLOOD OF MY FATHER AGE 75 YEARS TEST REPORT AS UNDER UREA 125MG/DL NORMAL RANGE 10-40 CREATININE 4.3 MG/DL NORMAL 0.9 1.4 SERUM SODIUM 144 MEQ/L NORMAL 135-155 SERUM POTASSIUM 5.2 MEQ/L NORMAL 3.5 5.2 4 Dyalisys done 4 protested done one month before what will be ur suggestion
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At the sight of a meth injection there is a golf ball size redness. Whole arm from shoulder to fingers is swollen really bad. Its been a couple of days so sign of swelling going down at all. What could be the problem. He doesn t want to go to ER he thinks the doctors will call the police
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Hi I had a big benign tumor on my nose .On 6th of feb that tumor was removed ... had stitches on nose and on the upper lip area ... quite big cut with many stitches .Had swelling in 1st week on my face , the 2nd week was much better ... in the end of third week again had swelling on the cheeks side of stitches ... Dr prescribed a course of Flucloaxcillin ... now there is a hard area around the stitches which is not swelling just like a lump .What it might be and how long will it take to go ?
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I been getting stinging,burning pain in my urine also have pain my left side stomach.the ultrasound is normal.urine test is normal,blood test is normal.i have taken two course of antibiotics but no changes.its been 3 week Im still the same what shall I do
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I nderwent laproscopy, hysteroscopy and biopsy and got to know that I am suffering from endometrial TB. My tubes are normal. I am on medicine Monto 3. Its about two months. I wanted to know that can i undergo IUI, can i get pregnant if on medication?
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Measurement of WC added limited information to BMI in this cohort.
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Epilepsy (Diagnosis): To diagnose your condition, your doctor will review your symptoms and medical history. Your doctor may order several tests to diagnose epilepsy and determine the cause of seizures. Your evaluation may include: - A neurological exam. Your doctor may test your behavior, motor abilities, mental function and other areas to diagnose your condition and determine the type of epilepsy you may have. - Blood tests. Your doctor may take a blood sample to check for signs of infections, genetic conditions or other conditions that may be associated with seizures. Your doctor may also suggest tests to detect brain abnormalities, such as: - Electroencephalogram (EEG). This is the most common test used to diagnose epilepsy. In this test, doctors attach electrodes to your scalp with a paste-like substance. The electrodes record the electrical activity of your brain. If you have epilepsy, it's common to have changes in your normal pattern of brain waves, even when you're not having a seizure. Your doctor may monitor you on video while conducting an EEG while you're awake or asleep, to record any seizures you experience. Recording the seizures may help the doctor determine what kind of seizures you're having or rule out other conditions. Your doctor may give you instructions to do something that will cause seizures, such as getting little sleep prior to the test. - High-density EEG. In a variation of an EEG test, your doctor may recommend high-density EEG, which spaces electrodes more closely than conventional EEG - about a half a centimeter apart. High-density EEG may help your doctor more precisely determine which areas of your brain are affected by seizures. - Computerized tomography (CT) scan. A CT scan uses X-rays to obtain cross-sectional images of your brain. CT scans can reveal abnormalities in your brain that might be causing your seizures, such as tumors, bleeding and cysts. - Magnetic resonance imaging (MRI). An MRI uses powerful magnets and radio waves to create a detailed view of your brain. Your doctor may be able to detect lesions or abnormalities in your brain that could be causing your seizures. - Functional MRI (fMRI). A functional MRI measures the changes in blood flow that occur when specific parts of your brain are working. Doctors may use an fMRI before surgery to identify the exact locations of critical functions, such as speech and movement, so that surgeons can avoid injuring those places while operating. - Positron emission tomography (PET). PET scans use a small amount of low-dose radioactive material that's injected into a vein to help visualize active areas of the brain and detect abnormalities. - Single-photon emission computerized tomography (SPECT). This type of test is used primarily if you've had an MRI and EEG that didn't pinpoint the location in your brain where the seizures are originating. A SPECT test uses a small amount of low-dose radioactive material that's injected into a vein to create a detailed, 3-D map of the blood flow activity in your brain during seizures. Doctors also may conduct a form of a SPECT test called subtraction ictal SPECT coregistered to MRI (SISCOM), which may provide even more-detailed results. - Neuropsychological tests. In these tests, doctors assess your thinking, memory and speech skills. The test results help doctors determine which areas of your brain are affected. Along with your test results, your doctor may use a combination of analysis techniques to help pinpoint where in the brain seizures start: - Statistical parametric mapping (SPM). SPM is a method of comparing areas of the brain that have increased metabolism during seizures to normal brains, which can give doctors an idea of where seizures begin. - Curry analysis. Curry analysis is a technique that takes EEG data and projects it onto an MRI of the brain to show doctors where seizures are occurring. - Magnetoencephalography (MEG). MEG measures the magnetic fields produced by brain activity to identify potential areas of seizure onset. Accurate diagnosis of your seizure type and where seizures begin gives you the best chance for finding an effective treatment.
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BACKGROUND: Social media enables the rapid consumption of news related to COVID-19 and serves as a platform for discussions. Its richness in text-based data in the form of posts and comments allows researchers to identify popular topics and assess public sentiment. Nonetheless, the vast majority of topic extraction and sentiment analysis based on social media is performed on the platform or country level and does not account for local culture and policies. OBJECTIVE: The aim of this study is to use location-based subreddits on Reddit to study city-level variations in sentiments toward vaccine-related topics. METHODS: Comments on posts providing regular updates on COVID-19 statistics in the Vancouver (r/vancouver, n=49,291), Toronto (r/toronto, n=20,764), and Calgary (r/calgary, n=21,277) subreddits between July 13, 2020, and June 14, 2021, were extracted. Latent Dirichlet allocation was used to identify frequently discussed topics. Sentiment (joy, sadness, fear, and anger) scores were assigned to comments through random forest regression. RESULTS: The number of comments on the 250 posts from the Vancouver subreddit positively correlated with the number of new daily COVID-19 cases in British Columbia (R=0.51, 95% CI for slope 0.18-0.29; P<.001). From the comments, 13 topics were identified. Two were related to vaccines, 1 regarding vaccine uptake and the other about vaccine supply. The levels of discussion for both topics were linked to the total number of vaccines administered (Granger test for causality, P<.001). Comments pertaining to either topic displayed higher scores for joy than for other topics (P<.001). Calgary and Toronto also discussed vaccine uptake. Sentiment scores for this topic differed across the 3 cities (P<.001). CONCLUSIONS: Our work demonstrates that data from city-specific subreddits can be used to better understand concerns and sentiments around COVID-19 vaccines at the local level. This can potentially lead to more targeted and publicly acceptable policies based on content on social media.
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Is autoclaving an effective method for killing prions?
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I have a iron deficiency my iron is at 14 and should be at 35 and because of that I am now anemic,I tried taking iron pills but they made me constipated and I tried iron in liquid form but it tasted terrible, is their any other way to get my iron up, can you take it in a shot etc...? Thanks
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Hello i am a 22 year old female i have a really bad cough that wont seem to go away, i have been coughing up mucus that seems to be white at times then watery and clear the next at times i will cough to the point i throw up, i have lost sleep due to cough spells as well i had this issue about two years ago and had xrays done on my lungs and the doctors said everything seemed to be clear, but lately i find it hard to breathe if i try to get a good draw of air i end up coughing or wheezing.
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Hi I'm 20 yrs old and I'm 5'2 I weight 128Lbs and I have no medical history.I had a bike accident 2 days ago and hit face first on concrete. My top lip got a cut and it was swollen. The paramedics that came that day said it was not a cut so bad and it would heel itself and to just place an ice pack for the swelling well I placed ice pack on it every 2hrs the whole day but the inflammation did not come down. My lip dosent feel like its swollen not it feels like maybe it has puss in it and that's why the lip is still swollen...should I go see a doctor? Or is this natural?
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Why Is Surgery Necessary?
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Hello im a 48yr old female I smoke and over the last few weeks I cant seem to get enough air and so I cant sleep I have a cold but im like this 3wks out of the month as I have lupus and always get sick, my question is do you know why I cant get my breath its terrifying? Please
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I am 37 years old male. I have a very big memory loss but not dymensia. I forget everything i do even words names . i dont thing this is normal cause i have very bad memory even near everyone near me(friends,family etc.) i dont smoke, drink alcohol, taking drugs, i am nervous . i work about 55 hours a weak . still i am always tired . i wish i can become normal in memory,
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my dad has been diagnosed with secondary liver cancer and there is no treatment available he is too frail. He is jaundiced and sleeps all the time although when awake is lucid and will hold a conversation. He has no appitite and eats very little - how long can i expect to have him around?
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What type of monoclonal antibodies are Rituximab and Cetuximab?
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I lived in Arizona for 2 years and in that time I did not do hardly any exercise. I sat around all day on the computer for school and did not stretch or run at all. I recently moved back to Ohio and enlisted in the National Guard but I have a big problem. I cannot jog without getting winded and my heart rate going up, my muscles all over my body are sore, my knees feel like they have pressure in them, my shoulders and neck ache, my left shoulder pops when I rotate it, my rib hurts on the left side and throughout my lowerback, I feel stiff, I shake when I bend over, my hands tremble slightly, and I get cramps on the bottom of my feet. I ran track and cross country before AZ and never had this. Now I feel like I cannot even do 10 push-ups. I am 18, 134 pounds, and 5'8 1/2. I am also a male. What's wrong with me?
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Hi Doctor,I want to speak to a gynaecologist I had my last period on 24th May 2014, and lasted till 29th. Me and my husband had sex on 30th and every alternate day we do have sex.I felt like vomitting a week later. I was tired all day. So took a pregnancy test but it was negative.We are planning to have a child.We have tried for 2 months but the result is negative Please suggest
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I have been taking Flonase for about a week now per my Dr s advice. I started it due to a lumpy feeling in throat and some hoarseness. The lumpy feeling is gone, but a slight sore throat now. Hoarseness is still a problem - better at some times than others. Now am getting some stomach discomfort and burping - nauseated feeling. Are these symptoms normal from using Flonase?
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Hello dr my mother had severe pain and she is admitted in hospital as she has stone in her gall bladder and doctor told that it swell due to infection and they cant operate it also till it get normal plz tell me that what she should eat in this situation.........and plz suggest which procedure is gud laser one or open operation plz reply fast
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My husband had surgery alittle over a year ago to have a non cancerous Intermuscular Lymphoma/fatty tumor removed from the back of his right shoulder , he is still having severe pain with this, is determined there is something going on in there, the tumor was about the size of a softball. Any suggestions on what it could be causing the pain after this long? Thank you for any help
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I am 47 years on BP medication for 6 months - amlopres-AT (two times a day). Now my BP is low or 110/70 the local doctors advised to take only one tab in the morning and skip the night dose. I am living in Sudan and my family doctor is in chennai India. What should I do now ?
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While SOAT1 activity is likely to be tightly regulated to maintain cholesterol homeostasis in normal podocytes, the possibility that altered SOAT1 activity contributes to podocyte injury in disease conditions warrants further investigation.
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My father has been a paraplegic since the early 80 s. His feet always swell during the summer but it is worse this summer. They get very swollen and look almost purple. I know that there are many causes (diet, his condition, etc) but what can he do to keep the swelling down to a min? Would compression socks help?
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Hi doctor, I had sex for the first time. After that, I did not get my periods yet. I went to a gynecologist. She had taken my blood sample and it was negative. But, still I have not gotten my periods and it has been a week ahead. What could be the reason for my late periods?
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Hi Am new to this site hope i will get answer for my problem very soon...Actually am 10 weeks pregnant..Now 11th week is running...I got itching and some skin rashes when am on 9th week..Still i have them ..I met my doctor then she prescribed me cetzine tablet for 2 days and gave me some lotion..I took those tablets after two days those spots are gone..But had little bit itching..3 days back again i got itchy skin and red spots over my body they looks like mosquito bytes small small red rashes..my doctor told me to consult skin specialist..But due to week end i could nt consult any doctor..Again i took cetzine tablet then got some relief..Now those red spots are clearing slowly but still have some itchy skin..I heard those things will be happen in third trimester but i have them at first trimester..Please doctor any one help me out..Can i take cetzine tablet when i have itch...Really am scaring about my baby this is my first pregnancy is there any effect to my baby ...? please hope you understand my tension...Thanks in advance look for your answer.. Thank you so much for this site..............
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At my doctors appointment this week he observed what appears to be a large amount of histamine in my blood (I turned red very easily and it lasted awhile) and I also noticed I get red and hot randomly while indoors or out and it take awhile to cool down, I am a 33 year old female. He suggested Zyrtec at night but the next day after taking it I got red and itchy on my arm and other areas became uncomfortable like needing to continually crack my neck, back and mainly my two fingers on my right hand. The pharmacy suggested Benadryl but that did not help. Now it s been going on a few days, my itchy red fingers hat continually need to be cracked for relief were swollen and red this morning and very painful near the joint and continue to be painful although swelling went down a good bit throughout he day. Now I am becoming itchy in other areas like my left hand and my left ear is now bright red and very hot. I also suddenly have unexplained brushing across my lower back and right side. I am very worried, what could this be?
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UNLABELLED Multiple host molecules are known to be involved in the cellular entry of filoviruses, including Ebola virus (EBOV); T-cell immunoglobulin and mucin domain 1 (TIM-1) and Niemann-Pick C1 (NPC1) have been identified as attachment and fusion receptors, respectively. However, the molecular mechanisms underlying the entry process have not been fully understood. We found that TIM-1 and NPC1 colocalized and interacted in the intracellular vesicles where EBOV glycoprotein (GP)-mediated membrane fusion occurred. Interestingly, a TIM-1-specific monoclonal antibody (MAb), M224/1, prevented GP-mediated membrane fusion and also interfered with the binding of TIM-1 to NPC1, suggesting that the interaction between TIM-1 and NPC1 is important for filovirus membrane fusion. Moreover, MAb M224/1 efficiently inhibited the cellular entry of viruses from all known filovirus species. These data suggest a novel mechanism underlying filovirus membrane fusion and provide a potential cellular target for antiviral compounds that can be universally used against filovirus infections. IMPORTANCE Filoviruses, including Ebola and Marburg viruses, cause rapidly fatal diseases in humans and nonhuman primates. There are currently no approved vaccines or therapeutics for filovirus diseases. In general, the cellular entry step of viruses is one of the key mechanisms to develop antiviral strategies. However, the molecular mechanisms underlying the entry process of filoviruses have not been fully understood. In this study, we demonstrate that TIM-1 and NPC1, which serve as attachment and fusion receptors for filovirus entry, interact in the intracellular vesicles where Ebola virus GP-mediated membrane fusion occurs and that this interaction is important for filovirus infection. We found that filovirus infection and GP-mediated membrane fusion in cultured cells were remarkably suppressed by treatment with a TIM-1-specific monoclonal antibody that interfered with the interaction between TIM-1 and NPC1. Our data provide new insights for the development of antiviral compounds that can be universally used against filovirus infections.
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Polycystic ovarian syndrome PCOS Summary Polycystic ovarian syndrome (PCOS) is a health problem that can affect a woman's menstrual cycle, ability to have children, hormones , heart, blood vessels, and appearance. Women with this condition typically have high levels of hormones called androgens, missed or irregular periods, and many small cysts in their ovaries. The cause of PCOS is unknown, but probably involves a combination of genetic and environmental factors . Treatment for PCOS may involve birth control pills and medications for diabetes and infertility. Medicines called anti-androgens are also used to speed the growth of hair and clear acne. [1] [2] Symptoms This table lists symptoms that people with this disease may have. For most diseases, symptoms will vary from person to person. People with the same disease may not have all the symptoms listed. This information comes from a database called the Human Phenotype Ontology (HPO) . The HPO collects information on symptoms that have been described in medical resources. The HPO is updated regularly. Use the HPO ID to access more in-depth information about a symptom. Showing of Medical Terms Other Names Learn More: HPO ID Percent of people who have these symptoms is not available through HPO Abnormality of metabolism/homeostasis Laboratory abnormality Metabolism abnormality 0001939 Amenorrhea Abnormal absence of menstruation 0000141 Autosomal dominant inheritance 0000006 Enlarged polycystic ovaries 0008675 Hirsutism Excessive hairiness 0001007 Obesity Having too much body fat 0001513 Oligomenorrhea 0000876 Showing of Find a Specialist If you need medical advice, you can look for doctors or other healthcare professionals who have experience with this disease. You may find these specialists through advocacy organizations, clinical trials, or articles published in medical journals. You may also want to contact a university or tertiary medical center in your area, because these centers tend to see more complex cases and have the latest technology and treatments. If you can't find a specialist in your local area, try contacting national or international specialists. They may be able to refer you to someone they know through conferences or research efforts. Some specialists may be willing to consult with you or your local doctors over the phone or by email if you can't travel to them for care. You can find more tips in our guide, How to Find a Disease Specialist. We also encourage you to explore the rest of this page to find resources that can help you find specialists. Healthcare Resources To find a medical professional who specializes in genetics, you can ask your doctor for a referral or you can search for one yourself. Online directories are provided by the American College of Medical Genetics and the National Society of Genetic Counselors. If you need additional help, contact a GARD Information Specialist. You can also learn more about genetic consultations from Genetics Home Reference.
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My 93 year old father fell this morning at his assisted living home - he is not "hurt" but cannot stand on his own, he threw up on himself, his blood pressure is 76/34 and his feet are really "dry" (toes stuck together?) Do you have an idea what is going on?
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I was diagnosed july 2013 and had surgery, chemo and brachytherapy for uterine cancer which was clear cell and adenocarcinoma. Treatment was complete on Nov 19, 2013. yesterday had some spotting and wondered how worried should I be. Went in to doctor and had pap, and CA125. I was diagnosed at stage Ia.
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My daughter is 2.10 yrs old. She has got a very bad habit of vomiting since her birth. Often she vomits after feeding. She doesn t love to eat. She is not at-all fond of any food, except chocolate. How to reduce her vomiting tendency and how to increase her interest in food.
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Some studies suggest that higher fear of crime was associated with lower levels of walking, and higher perceived danger for pedestrians and cyclists was associated with increases in car use [66], although some studies found no associations between changes in perceptions of safety and walking [67].
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3 weeks before I masturbated at night and slept.. Next day morning I noticed an uncomfortable feeling on my Penis.. A feeling of pressure.. I was not able find out what was going on. I stopped masturbation for 2 -3days and it subsided but not completely.. After that I again started masturbation and the feeling came back.. 1day ago I noticed a lump under my Penis.. What is this thing and how clan i cure it..pls help
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Hi doctor, I am a 22 year old female. I have a dusky skin that is brown skin. I want to become fair. Can I use Kojivit gel? Or any other dermoatology cream can I use? My hands are also brown in color and full of tan. Do you suggest any creams to get fair? I want to become fair as my marriage is going to get fixed by next year. Please suggest me some creams, so that it should not show any side effects. Also, how long I should use it? If I use anything, then will it have any effect in case of pregnancy, etc? Please help me. Thanks in advance.
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A relative is now hospitalized with seizures and an elevated blood sugar of over 1300. Has had recent hospitalizations with seizure activity. One doc said was not related to blood sugar. Another says, yes. Would a lumbar puncture be warranted to further evaluated?
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I m 13, and has recently undergone circumcision, it s been a day now since the surgery, there is this two big lumps that is caused by the circumcision, it is swollen and I am worrying about it, is it normal to have this kind of two lumps, not that big but its bigger than my glans, although my uncle who is a nurse said its normal, I need clarification and also some quick tips how to heal faster. Note
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My daughter is almost 7 yrs. old. On Friday and Saturday, she had a fever, on and off. Yesterday and today (for over 36 hours) no fever. Now she has been complaining that her chest and throat hurt - and says her chest pain is worse when she lies down? I m taking her to the doctor as soon as their lunch ends at 1:45, but was wondering what this could possibly be? Is it serious or perhaps just a pulled muscle?
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hi i am 32 years old, & i have been materbating since the age of 10. recently i have had a a girl freind & we tried making out. we do it atleast ones a month, but ejaculate in less than 20 seconds. i have taken anti dipressants as pescribed by a urologist & taken otherherbal medines but nothing helps. now i feel i loose eraction faster than before. please advice.
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Hello doctor,I just got one side of my wisdom teeth removed both upper and lower six days ago, and I have another one scheduled after two days for the left side. The upper is 100 % fine, which they pulled. The lower they pulled the tooth without removing the root because it was too close to the nerve. I do have some stitching in this area currently on the lower cheek. Noticed a hard lump about 1 inch between my lower jawline and cheek area. Is this normal because of swelling or something else. Currently taking Amoxicillin 500 mg and Ibuprofen 600 mg. Please let me know what this hard lump is, also generally on the lower side where this lump is, remains sore.
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My 11 year old daughter just had a Renal US...showed moderate right pelvocaliectasis. Minimal intermittent dilatatioln of the distal right ureter. The urinary wall is well distended and is normal in morphology. The bladder wall is moderatelly thickened. There is an echogenic mound at the level of the right UVJ compatible with the clinical history of Deflux. Mobile echogenic material is present within the bladder.
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i have a really unusual nervous problem where i cant walk properly,talk propaly,look normal etc.and it only happens when i get nervous,which is 90% of the time,even when im alone it happens.what can i do to be able 2 live a normal life and how did i get so bad off?
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BACKGROUND: Palliative care phases (stable, unstable, deteriorating, terminal and bereavement) are routinely used in Australia and the UK to describe the clinical situation of patients and their families and to evaluate the associated care plan. In addition, it serves as a benchmark developed by the Australian Palliative Care Outcome Collaboration (PCOC) and is used nationwide for comparisons between services. In Germany, the concept is not used consistently due to various translations. Furthermore, there is no nationwide systematic approach to routinely assess clinical outcomes in palliative care. The study aims to develop a German version of the palliative care phase definitions by adapting them culturally, and to examine the inter-rater reliability of the adjusted definitions with healthcare professionals. METHODS: Mixed-methods approach: Cognitive interview study using ‘think aloud’ and verbal probing techniques and a consecutive multi-center cross-sectional study with two clinicians independently assigning the phase definitions. Interviewees/participants were selected through convenience and purposive sampling in specialist palliative care inpatient units, advisory and community services and in three specialist palliative care units with doctors, nursing staff and allied health professionals. RESULTS: Fifteen interviews were conducted. Identified difficulties were: Some translated terms were 1) not self-explanatory (e.g. ‘family/carer’ or ‘care plan’) and (2) too limited to the medical dimension neglecting the holistic approach of palliative care. (3) Problems of comprehension regarding the concept in general occurred, e.g. in differentiating between the ‘unstable’ and ‘deteriorating’ phase. Inter-rater reliability was moderate (kappa = 0.44; 95% CI = 0.39–0.52). The assignment of the phase ‘deteriorating’ has caused the most difficulties. CONCLUSION: Overall, the adapted palliative care phases are suitable to use in the German specialist palliative care setting. However, the concept of the phases is not self-explanatory. To implement it nationwide for outcome measurement/benchmarking, it requires further education, on-the-job training and experience as well as the involvement of healthcare professionals in implementation process. For the use of international concepts in different healthcare systems, a deeper discussion and cultural adaptation is necessary besides the formal translation. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12904-021-00825-z.
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Hi my name is Hayley, my brother in law has been taken into hospital because he is not able to lift his arms up, he has just been to the caribbean, the doctors at the hospital are unsure what the problem is and running tests, they are presuming it may be glandular fever at this time is there anything you may suggest? Thank you Hayley
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hello my name is lisa and my granddaughter has a red rash that i thought might be related to a allergic reaction because i have changed my laundry detergent, but i have also found out that measles is also going around so i am concerened what does measels look like and what are the signs of measels that i should be looking for . my email is YYYY@YYYY
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I had a tooth pulled three weeks ago and it seems to be ok , just saw dentist yesterday to have stitches pulled. Also have gotten some kind of sinus thing that had subsided and come back worse a few days ago. I just looked in my mouth and the roof of my mouth is noticeably yellow. Its towards the back and on the sides in the back. What could this be?
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What to expect if I have Occupational lung disease (Outlook/Prognosis)?
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Under which class of HAART drugs does Lopinavir belong?
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Hi doctor, I had sex for the first time. After that, I did not get my periods yet. I went to a gynecologist. She had taken my blood sample and it was negative. But, still I have not gotten my periods and it has been a week ahead. What could be the reason for my late periods?
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i have a sore throat, a slight cough as well as slightly dry eyes. i may have been in contact with individuals with covid-19 but unknowingly?
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My mom ,92 has a compression fracture in T 12. What type of back brace would benefit here. She has been prescribed a nascott tlso back brace but it appears to rigid and presses heavily in her sternum. Rides up an hits her an her Adam s apple when sitting and makes swallowing difficult. It has a rigid hard plastic shell with Velcro straps and a triangular hard plastic sternum piece. What are your thoughts? She hates the way it feels around her neck and sternum area.
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BACKGROUND: Rapid antigen tests (RATs) may be included in national strategies for handling the SARS-CoV-2 pandemic, as they provide test results rapidly, are easily performed outside laboratories, and enable immediate contract tracing. However, before implementation further clinical evaluation of test sensitivity is warranted. OBJECTIVES: To examine the performance of Abbott’s Panbio(TM) COVID-19 Ag Rapid Test Device for SARS-CoV-2 testing in a low to medium prevalence setting in Norway. STUDY DESIGN: A prospective study comparing the results of the Panbio RAT with PCR in 4857 parallel samples collected at a SARS-CoV-2 test station in Oslo, and from COVID-19 outbreaks in six Norwegian municipalities. RESULTS: A total of 4857 cases were included in the study; 3991 and 866 cases from the test station and the outbreak municipalities, respectively. The prevalence at the test station in Oslo was 6.3 %, and the overall sensitivity of the RAT was 74 %. Increased sensitivity was observed in patients who experienced symptoms (79 %) and when considering samples with viral loads above estimated level of infectivity (84 %), while it was lower in asymptomatic persons (55 %). In the outbreak municipalities, the overall prevalence was 6.9 %, and the total sensitivity of the RAT was 70 %. CONCLUSIONS: Our results indicate that the test correctly identified most infectious individuals. Nevertheless, the sensitivity is considerably lower than for PCR, and it is important that the limitations of the test are kept in mind in the follow-up of tested individuals.
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Hi doctor my wife is suffering from severe body pain and stress and stretch in whole body. She is consulting doctor since last 2 year s he is taking duvanta 20 in morning and pregeb od 75 in night. She is suffering from severe stretching in her body many times a day and after that she gets faints. We have brain ct scan done but reports are normal.she is advised to take levipil 500. But she have Developed heavy allergy in her whole body. Kindly suggest can she take allergy medicine along with this levipil 500. Or Suggestions for any other alternative.
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sir, my baby aged about 15 ye 5 m 21 days was chronic cough with sputum and blood. She was admitted in the hospital and at the first instance, the test for cystic fibrosis, deta 508 and sweet chloride was conducted which come in nagative and normal 32. Latter on her echo of heart was taken and dignosed as pulmonary hypertension as such, she was admitted in cardio hospital, where cultural test was conducted and cholestic sulphate injunction was given and after 6 hours she passed away. NOw my son sindh yar aged about 10 years having morning cough with small sputum , sneezing,irritation, poor health, i do not want to loose him. please tell me what kind of test should be taken so that the disease can be dignosed
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I used braces 8 years ago and I use retainers to sleep only. Last week I went to the dentist because I feel a snap when I close and open my mouth.The Dentist told me that I grind my teeth and he suggest me to use a night guard, and change one of the retainers. He told me that the snap will stop when I use the night guard. My question is should I use the night guard or continuing with the old retainers?cm
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Hi, about a week ago I purchased a male sex toy (Fleshlight), the toy was sealed when purchased and my partner used it twice on me on two separate occasions, after which the toy was cleaned and sterilised.Since then the head of my penis has been itchy and sore, almost like chaffing, I have tried masturbating to check for any sign of infection and my ejaculate was thick and congealed, should I be concerned for infection and what what you reccomend to ease the itching. If it helps I am a 20 year old male and my only sexual partner has been my current.
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I just received a call from my neuro that my liver functions are elevated and he wants me to stop Copaxone injections for one month. I have MS and have been on Copaxone since 2005. I am also on Estriol 8 mg (I was in a clinical trial) I am doing and feeling great. Bilirubin 1.28 direct .27 indirect 1.01 Otherwise I am very healthy Chloresterol 164 low blood pressure 5 7 137 pounds age 54 and very upset about this. Any thoughts?
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Hi doctor, I am a 28 year old female, and I am on birth control pills (Femilon) for the past three months. In the first month, bleeding started on the third pill-free day, and that time I bled on the first and second day. The bleeding was less, and I used only one pad that was not filled. From the third day, I started normal bleeding until the sixth day. In the second month, I finished my pack on the 19th, and I got my period on the sixth pill-free day. At that time, I bled a little amount for three or four days. And in the third month, I finished my pack on the 16th, and I got my period on the seventh pill-free day but, I bled minimal amount, not even one pad was soaked completely for three days and finished on the fourth day. Is it normal during birth control pills or is it a side effect of the pill? Should I stop or continue the pills? I am confused. Please help.
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Hello doctor my sister is 35 ys old diagnosed as schizoph.at 25 ys age, she treated with modecate & drugs bec she hearing delusion ,she became well after 3-6 month from treatment then she discontinue drugs &refuse to went to any doctor after that she say she isnot crazy, she without any treatment for 8-9 ys she have no job ,she booring from home,say that people are bad &joulus from her &don’t want good to her she obsessive & wash several time in day but these stange talk not say it aways & she don’t say it only with her family not outside or infront of other people ??she be enjoy when we go for picnic & feel better please dr. what my sister have is she realy sick or not? She need treatment or not? Its good for her to work in job or may be she cant tolerate people & say strange things to them??Thanks a lot Lina
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Hi my name is April,Just recently I had an MRI done on my breast and the test results came back that my breasts were ok, but I have a cysts on my spleen. This morning I got a Ultrasound done on my spleen. Can you please tell me what I have to look forward to? Is it cancer? Right now I have no symtoms of soreness in that area, but I tend to get very bloated at the end of the day. I m very scared right now and I will not hear from my doctor until some time next week.
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Hi my name is Ashley. I have had really bad upper back pain for 2 weeks now. When I pull my arms forward or move my head the pain is worse. It feels sore all the time and when I do move my arms it is like a stabbing pain from shoulder blade to shoulder blade and up to my neck I also have pain I’m my shoulders. I have no idea what this is and I am very worried that it could be something very serious. I do have health anxiety so my first thought of course is that it could be related to my heart.I have had several EKGS in the last 6 months all fine and ECHO at the end of 2012. Could this be my heart or what could this be? I have had no injury that I know of.
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My daughter had a double lung transplant 4 years ago due to CF, No problems whatsoever. FV1 on 2/3/2014 was114%. She now has acute rejection (A4 Severe) along with pneumonia. She s in the hospital in NY Presbyterian. Can she ever get back to the way she was before this started? I am sick with worry about this. Thank you.
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This is general question. what is laparoscopy? Why it is done? Any risks?
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just like when you crack your knuckles or back or whatever.Been going on for a couple of days. Leaned back in a chair and felt a crack or pop in my sternum. It felt good and I ve felt the need to do it again whenever I feel a bit of tightness in my sternum. Now I can just do it by spreading arms and expanding the chest cavity. Is this normal? I lift weight 4 day a week. upper body on Mondays and Wednesdays
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I am 47yrs.I have founded stage4 breast cancer 6 months ago.. The oncologist offered a Fermira first, then 11/2 mon later changed to timoxifen about two months.. I got second opinion at mdanderson. The doc said needed to xeloda&avastin treatment. I know that there is no cure, but is this helpful for my condition now. . Honestly, I don t want to treatment like that pain to make me to live longer.. What is best ? the pain with long life with chemo, or try to live every moment best..
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The British Occupational Hygiene Society (BOHS) Covid-19 Working Group developed a control banding matrix to provide guidance for employers and others to help assess the risks of Covid-19 infection during the pandemic. The matrix was based on occupational hygiene principles and the judgement of the occupational health practitioners involved; since objective data on workers’ exposure were unavailable. Users of the matrix identify one of five exposure categories based on generic job descriptions and example occupations, and these categories are linked to generic guidance on interventions at source, on the exposure pathway and for individual workers. The risk matrix was published on the BOHS website and the guidance has been downloaded more than 2000 times. The matrix has had limited evaluation for reliability, but the data suggest that the highest exposure ranked jobs were associated with higher age-standardized mortality in Britain during the pandemic. However, there was considerable variability in exposure assignments between assessors, which underlines the need for the control guidance to be precautionary. The BOHS calls on academic researchers to undertake further work to validate the reliability of the tool.
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HEllo, i have varicocele (of the Shunt kind) and i am also a fitness freak. So for the moment i am using both amino acids and a medium fat burner (for the first time). I sometimes have some strange feeling in my lower abdomen, on the right... it is not my abdomen, it is lower than that but i donnow what is the name of this area... jsut wanted to know is it important or not? should i avoid some specific excercises such as abdominal moves? thanks
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My query is related to Fileria. Specifically, my wife has had the disease which manifested itself some 12 years ago. It strangely disappeared. Over the past year she has been experiencing different types of ailments with no particular diagnosis. From my own research it seems quite likely that a 'dormant' or medially equivelent worm has begun to infect again, doing something to the lymphatic system causing 1. Pain in her reproductive region (swelling discovered through a synogrophy) 2. pain and thickening of her thigh 3. Nausea 4. Dizziness 5. Shaking involuntarily of her leg, 6. Swelling under her arm pits 7. profuse sweating at times of stress in particular (again under the arms), 8. exhaustion and fatigue without exertion, 9. arthritic pain mobile throughout her body.
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i am a girl of 28 years not yet married, i am having pain in left lower abdomen rarely. i had gone uterus operation 2 years before for some pain and a tissue in it. few days back i had very high fever and cold can't able to have food, if i had immediate vomiting it only orange/sweet lime juice i can have. may be because of it i am getting pain?
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Ihad a teeth cleaning that I was told they went pretty deep. Within about two hours I was nauseous and so cold that I could not get warm. I actually had three blankets and a heating pad on me and was still freezing. The next day I still have an upset stomach anddiarhea. What happened and do I need to do anything at this point?
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Doctor i get wet dreams in a period of six days sometimes i get them within the period of 13 day.Doctor in a month i get wet dreams more the 2 times.Is this act normal ? or what shall i do to stop this fast nightmares.Doctor please note that i am a 16 years old boy and i use to masturbate from past 2-3 years and now i have stopped it.
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These findings may have important implications for understanding negative alcohol-related behaviours and promote the consideration of social context, social pressure and social cognitive abilities in the development of public policy and targeted interventions to prevent alcohol-related antisocial behaviours.
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I have been doing a lot of physical activity ( gardening, cleaning & all other household chores ) + a part time job involving being on the computer for long hours during the last one month a& I feel Im exhausted and have chest pain. should I seek medical help
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Hello Doctor,Recently, i have started feeling sleepy and sometime runs tired easily. i have treated malaria fever in the last 3 weeks with coaterm (aletermineter and numerfantrin). at work i feel easily sleepry, please help me for recommendationmy age is 34,height is about 1.73M and weight about 79-80KG, Medical history - My father has high Blood Pressure but is been managed
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I have a family history of heart disease- my father & brother died at 50 & according to lipid profile I have the same condition. I drink 10 to 16oz 80 vodka every day - does that impact my trigycerides / lipid profile ? I am on meds- see a cardio doc 2x s/yr and otherwise don t abuse myself/ non smoker
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