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<|startoftext|><L>CCCc1ccc([C@]2(C)NC(<mask_1:5>N(CC(=O)N[C@H](C)c3ccccc3OC)C2=O)cc1<mask_1:5> | 3 | 20 | 5 | =O) | 5 | CCCc1ccc([C@]2(C)NC(=O)CCN(CC(=O)N[C@H](C)c3ccccc3OC)C2=O)cc1 | CCCc1ccc([C@]2(C)NC(=O)N(CC(=O)N[C@H](C)c3ccccc3OC)C2=O)cc1 | =O)CC |
<|startoftext|><L>CCCc1c<mask_1:4>cc([C@]2(C)NC(=O)N(CC(=O)N[C@H](C)c3ccccc3OC)C2=O)cc1<mask_1:4> | 0 | 6 | 4 | 4 | CCCc1c(Cl)cc([C@]2(C)NC(=O)N(CC(=O)N[C@H](C)c3ccccc3OC)C2=O)cc1 | CCCc1ccc([C@]2(C)NC(=O)N(CC(=O)N[C@H](C)c3ccccc3OC)C2=O)cc1 | (Cl) |
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<|startoftext|><L>CCCc1ccc([C@]2(C)NC(=O)<mask_1:4>CC(=O)N[C@H](C)c3ccccc3OC)C2=O)cc1<mask_1:4> | 2 | 23 | 4 | N( | 4 | CCCc1ccc([C@]2(C)NC(=O)N(CCCC(=O)N[C@H](C)c3ccccc3OC)C2=O)cc1 | CCCc1ccc([C@]2(C)NC(=O)N(CC(=O)N[C@H](C)c3ccccc3OC)C2=O)cc1 | N(CC |
<|startoftext|><L>CCCc1ccc(<mask_1:5>NC(=O)N(CC(=O)N[C@H](C)c3ccccc3OC)C2=O)cc1<mask_1:5> | 8 | 9 | 5 | [C@]2(C) | 5 | CCCc1ccc(/C=C2NC(=O)N(CC(=O)N[C@H](C)c3ccccc3OC)C2=O)cc1 | CCCc1ccc([C@]2(C)NC(=O)N(CC(=O)N[C@H](C)c3ccccc3OC)C2=O)cc1 | /C=C2 |
<|startoftext|><L>CCCc1ccc([C@]2(C)NC(=O)N(CC(<mask_1:7>[C@H](C)c3ccccc3OC)C2=O)cc1<mask_1:7> | 4 | 28 | 7 | =O)N | 7 | CCCc1ccc([C@]2(C)NC(=O)N(CC(=O)N(C)[C@H](C)c3ccccc3OC)C2=O)cc1 | CCCc1ccc([C@]2(C)NC(=O)N(CC(=O)N[C@H](C)c3ccccc3OC)C2=O)cc1 | =O)N(C) |
<|startoftext|><L>CCCc1ccc([C@]2(C)NC(=O)N(CC(=O)N<mask_1:3>c3ccccc3OC)C2=O)cc1<mask_1:3> | 8 | 32 | 3 | [C@H](C) | 3 | CCCc1ccc([C@]2(C)NC(=O)N(CC(=O)NCCCc3ccccc3OC)C2=O)cc1 | CCCc1ccc([C@]2(C)NC(=O)N(CC(=O)N[C@H](C)c3ccccc3OC)C2=O)cc1 | CCC |
<|startoftext|><L>CCCc1ccc([C@]2(C)NC(=O)N(CC<mask_1:4>[C@H](C)c3ccccc3OC)C2=O)cc1<mask_1:4> | 5 | 27 | 4 | (=O)N | 4 | CCCc1ccc([C@]2(C)NC(=O)N(CC(=O)[C@H](C)c3ccccc3OC)C2=O)cc1 | CCCc1ccc([C@]2(C)NC(=O)N(CC(=O)N[C@H](C)c3ccccc3OC)C2=O)cc1 | (=O) |
<|startoftext|><L>CCCc1ccc([C@]<mask_1:5>(C)NC(=O)N(CC(=O)N[C@H](C)c3ccccc3OC)C2=O)cc1<mask_1:5> | 1 | 13 | 5 | 2 | 5 | CCCc1ccc([C@]2(C)C(C)NC(=O)N(CC(=O)N[C@H](C)c3ccccc3OC)C2=O)cc1 | CCCc1ccc([C@]2(C)NC(=O)N(CC(=O)N[C@H](C)c3ccccc3OC)C2=O)cc1 | 2(C)C |
<|startoftext|><L>C<mask_1:4>1ccc([C@]2(C)NC(=O)N(CC(=O)N[C@H](C)c3ccccc3OC)C2=O)cc1<mask_1:4> | 3 | 1 | 4 | CCc | 4 | CCCCc1ccc([C@]2(C)NC(=O)N(CC(=O)N[C@H](C)c3ccccc3OC)C2=O)cc1 | CCCc1ccc([C@]2(C)NC(=O)N(CC(=O)N[C@H](C)c3ccccc3OC)C2=O)cc1 | CCCc |
<|startoftext|><L>CCCc1ccc([C@]2(C)NC(=O)<mask_1:8>CC(=O)N[C@H](C)c3ccccc3OC)C2=O)cc1<mask_1:8> | 2 | 23 | 8 | N( | 8 | CCCc1ccc([C@]2(C)NC(=O)N(CC(=O)CC(=O)N[C@H](C)c3ccccc3OC)C2=O)cc1 | CCCc1ccc([C@]2(C)NC(=O)N(CC(=O)N[C@H](C)c3ccccc3OC)C2=O)cc1 | N(CC(=O) |
<|startoftext|><L>C<mask_1:5>csc(Nc2nccnc2[C@H]2CCCN(Cc3cnn(C)c3)C2)n1<mask_1:5> | 2 | 1 | 5 | c1 | 5 | COCCc1csc(Nc2nccnc2[C@H]2CCCN(Cc3cnn(C)c3)C2)n1 | Cc1csc(Nc2nccnc2[C@H]2CCCN(Cc3cnn(C)c3)C2)n1 | OCCc1 |
<|startoftext|><L>Cc1csc(Nc2nccnc2[C@H]2CCCN(Cc3<mask_1:3>nn(C)c3)C2)n1<mask_1:3> | 1 | 30 | 3 | c | 3 | Cc1csc(Nc2nccnc2[C@H]2CCCN(Cc3ccnnn(C)c3)C2)n1 | Cc1csc(Nc2nccnc2[C@H]2CCCN(Cc3cnn(C)c3)C2)n1 | ccn |
<|startoftext|><L>Cc1csc(Nc2nccnc2[C@H]2CCCN(Cc3c<mask_1:3>3)C2)n1<mask_1:3> | 6 | 31 | 3 | nn(C)c | 3 | Cc1csc(Nc2nccnc2[C@H]2CCCN(Cc3ccsc3)C2)n1 | Cc1csc(Nc2nccnc2[C@H]2CCCN(Cc3cnn(C)c3)C2)n1 | csc |
<|startoftext|><L>Cc1csc(N<mask_1:3>cnc2[C@H]2CCCN(Cc3cnn(C)c3)C2)n1<mask_1:3> | 4 | 8 | 3 | c2nc | 3 | Cc1csc(Nc2scnc2[C@H]2CCCN(Cc3cnn(C)c3)C2)n1 | Cc1csc(Nc2nccnc2[C@H]2CCCN(Cc3cnn(C)c3)C2)n1 | c2s |
<|startoftext|><L>Cc1csc(Nc2nccnc2[C@H]2CCCN(Cc3cnn(C)<mask_1:6>)C2)n1<mask_1:6> | 2 | 36 | 6 | c3 | 6 | Cc1csc(Nc2nccnc2[C@H]2CCCN(Cc3cnn(C)c3)C(C)C2)n1 | Cc1csc(Nc2nccnc2[C@H]2CCCN(Cc3cnn(C)c3)C2)n1 | c3)C(C |
<|startoftext|><L>Cc1cs<mask_1:5>Nc2nccnc2[C@H]2CCCN(Cc3cnn(C)c3)C2)n1<mask_1:5> | 2 | 5 | 5 | c( | 5 | Cc1csc(SCCNc2nccnc2[C@H]2CCCN(Cc3cnn(C)c3)C2)n1 | Cc1csc(Nc2nccnc2[C@H]2CCCN(Cc3cnn(C)c3)C2)n1 | c(SCC |
<|startoftext|><L>Cc1c<mask_1:4>Nc2nccnc2[C@H]2CCCN(Cc3cnn(C)c3)C2)n1<mask_1:4> | 3 | 4 | 4 | sc( | 4 | Cc1ccnc(Nc2nccnc2[C@H]2CCCN(Cc3cnn(C)c3)C2)n1 | Cc1csc(Nc2nccnc2[C@H]2CCCN(Cc3cnn(C)c3)C2)n1 | cnc( |
<|startoftext|><L>Cc1csc(Nc2nccnc2<mask_1:3>@H]2CCCN(Cc3cnn(C)c3)C2)n1<mask_1:3> | 2 | 16 | 3 | [C | 3 | Cc1csc(Nc2nccnc2[C@@H]2CCCN(Cc3cnn(C)c3)C2)n1 | Cc1csc(Nc2nccnc2[C@H]2CCCN(Cc3cnn(C)c3)C2)n1 | [C@ |
<|startoftext|><L>Cc1csc(Nc2nccnc2[C@H]2CCCN(Cc3c<mask_1:3>3)C2)n1<mask_1:3> | 6 | 31 | 3 | nn(C)c | 3 | Cc1csc(Nc2nccnc2[C@H]2CCCN(Cc3ccsc3)C2)n1 | Cc1csc(Nc2nccnc2[C@H]2CCCN(Cc3cnn(C)c3)C2)n1 | csc |
<|startoftext|><L>Cc1csc(Nc2nccnc2[C<mask_1:1>2CCCN(Cc3cnn(C)c3)C2)n1<mask_1:1> | 3 | 18 | 1 | @H] | 1 | Cc1csc(Nc2nccnc2[C]2CCCN(Cc3cnn(C)c3)C2)n1 | Cc1csc(Nc2nccnc2[C@H]2CCCN(Cc3cnn(C)c3)C2)n1 | ] |
<|startoftext|><L>O=C(c1cncc(-c2cccc<mask_1:6>)c1)N1CCO[C@@H](Cn2cccn2)C1<mask_1:6> | 2 | 18 | 6 | n2 | 6 | O=C(c1cncc(-c2cccc(Cl)c2)c1)N1CCO[C@@H](Cn2cccn2)C1 | O=C(c1cncc(-c2ccccn2)c1)N1CCO[C@@H](Cn2cccn2)C1 | (Cl)c2 |
<|startoftext|><L>O=C(c1cncc(-c2ccccn2)c1)N1C<mask_1:1>CO[C@@H](Cn2cccn2)C1<mask_1:1> | 0 | 27 | 1 | 1 | O=C(c1cncc(-c2ccccn2)c1)N1CCCO[C@@H](Cn2cccn2)C1 | O=C(c1cncc(-c2ccccn2)c1)N1CCO[C@@H](Cn2cccn2)C1 | C |
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<|startoftext|><L>O=C(c1cncc(-c<mask_1:5>2)c1)N1CCO[C@@H](Cn2cccn2)C1<mask_1:5> | 6 | 13 | 5 | 2ccccn | 5 | O=C(c1cncc(-c2ccoc2)c1)N1CCO[C@@H](Cn2cccn2)C1 | O=C(c1cncc(-c2ccccn2)c1)N1CCO[C@@H](Cn2cccn2)C1 | 2ccoc |
<|startoftext|><L>O=C(c1cncc(<mask_1:6>cccn2)c1)N1CCO[C@@H](Cn2cccn2)C1<mask_1:6> | 4 | 11 | 6 | -c2c | 6 | O=C(c1cncc(NCCc2ccccn2)c1)N1CCO[C@@H](Cn2cccn2)C1 | O=C(c1cncc(-c2ccccn2)c1)N1CCO[C@@H](Cn2cccn2)C1 | NCCc2c |
<|startoftext|><L>O=C(c1cncc(-c2ccccn2)c1)N1CC<mask_1:4>@@H](Cn2cccn2)C1<mask_1:4> | 3 | 28 | 4 | O[C | 4 | O=C(c1cncc(-c2ccccn2)c1)N1CCCO[C@@H](Cn2cccn2)C1 | O=C(c1cncc(-c2ccccn2)c1)N1CCO[C@@H](Cn2cccn2)C1 | CO[C |
<|startoftext|><L>O=C(c1cncc(-c2ccccn2)c1)N1CCO[C@@H](Cn2c<mask_1:1>2)C1<mask_1:1> | 3 | 40 | 1 | ccn | 1 | O=C(c1cncc(-c2ccccn2)c1)N1CCO[C@@H](Cn2cn2)C1 | O=C(c1cncc(-c2ccccn2)c1)N1CCO[C@@H](Cn2cccn2)C1 | n |
<|startoftext|><L>O=C(c1cncc(-c2ccccn2)c1)N1CCO[<mask_1:5>n2cccn2)C1<mask_1:5> | 7 | 30 | 5 | C@@H](C | 5 | O=C(c1cncc(-c2ccccn2)c1)N1CCO[C@H](n2cccn2)C1 | O=C(c1cncc(-c2ccccn2)c1)N1CCO[C@@H](Cn2cccn2)C1 | C@H]( |
<|startoftext|><L>O=C(c1cncc<mask_1:7>cccn2)c1)N1CCO[C@@H](Cn2cccn2)C1<mask_1:7> | 5 | 10 | 7 | (-c2c | 7 | O=C(c1cncc(NCCc2ccccn2)c1)N1CCO[C@@H](Cn2cccn2)C1 | O=C(c1cncc(-c2ccccn2)c1)N1CCO[C@@H](Cn2cccn2)C1 | (NCCc2c |
<|startoftext|><L>O=C(c1cncc(-c2ccccn2)c1)N1CCO[C@@H]<mask_1:5>cn2)C1<mask_1:5> | 6 | 35 | 5 | (Cn2cc | 5 | O=C(c1cncc(-c2ccccn2)c1)N1CCO[C@@H](c2cscn2)C1 | O=C(c1cncc(-c2ccccn2)c1)N1CCO[C@@H](Cn2cccn2)C1 | (c2cs |
<|startoftext|><L>O=C(c1cncc(-c2ccccn2)c1)N1CCO[C@@H](C<mask_1:2>)C1<mask_1:2> | 7 | 37 | 2 | n2cccn2 | 2 | O=C(c1cncc(-c2ccccn2)c1)N1CCO[C@@H](CCO)C1 | O=C(c1cncc(-c2ccccn2)c1)N1CCO[C@@H](Cn2cccn2)C1 | CO |
<|startoftext|><L>CCOC(<mask_1:7>C(=N/Nc1ccc([N+](=O)[O-])cc1)N1CCCc2ccccc21<mask_1:7> | 4 | 5 | 7 | =O)/ | 7 | CCOC(=O)CS/CC(=N/Nc1ccc([N+](=O)[O-])cc1)N1CCCc2ccccc21 | CCOC(=O)/C(=N/Nc1ccc([N+](=O)[O-])cc1)N1CCCc2ccccc21 | =O)CS/C |
<|startoftext|><L>CC<mask_1:4>(=O)/C(=N/Nc1ccc([N+](=O)[O-])cc1)N1CCCc2ccccc21<mask_1:4> | 2 | 2 | 4 | OC | 4 | CCCCOC(=O)/C(=N/Nc1ccc([N+](=O)[O-])cc1)N1CCCc2ccccc21 | CCOC(=O)/C(=N/Nc1ccc([N+](=O)[O-])cc1)N1CCCc2ccccc21 | CCOC |
<|startoftext|><L><mask_1:4>)/C(=N/Nc1ccc([N+](=O)[O-])cc1)N1CCCc2ccccc21<mask_1:4> | 7 | 0 | 4 | CCOC(=O | 4 | CN(C)/C(=N/Nc1ccc([N+](=O)[O-])cc1)N1CCCc2ccccc21 | CCOC(=O)/C(=N/Nc1ccc([N+](=O)[O-])cc1)N1CCCc2ccccc21 | CN(C |
<|startoftext|><L>CCO<mask_1:5>O)/C(=N/Nc1ccc([N+](=O)[O-])cc1)N1CCCc2ccccc21<mask_1:5> | 3 | 3 | 5 | C(= | 5 | CCOCCC(=O)/C(=N/Nc1ccc([N+](=O)[O-])cc1)N1CCCc2ccccc21 | CCOC(=O)/C(=N/Nc1ccc([N+](=O)[O-])cc1)N1CCCc2ccccc21 | CCC(= |
<|startoftext|><L>CCOC(=O)/C<mask_1:6>ccc([N+](=O)[O-])cc1)N1CCCc2ccccc21<mask_1:6> | 7 | 10 | 6 | (=N/Nc1 | 6 | CCOC(=O)/C(=C/c1ccc([N+](=O)[O-])cc1)N1CCCc2ccccc21 | CCOC(=O)/C(=N/Nc1ccc([N+](=O)[O-])cc1)N1CCCc2ccccc21 | (=C/c1 |
<|startoftext|><L>CCOC(=O)/C(=N/Nc1ccc([N+](=O)<mask_1:4>])cc1)N1CCCc2ccccc21<mask_1:4> | 3 | 29 | 4 | [O- | 3 | CCOC(=O)/C(=N/Nc1ccc([N+](=O)[O-])cc1)N1CCCc2ccccc21 | CCOC(=O)/C(=N/Nc1ccc([N+](=O)[O-])cc1)N1CCCc2ccccc21 | [O- |
<|startoftext|><L>CCOC(=O)/C(=N/Nc<mask_1:3>ccc([N+](=O)[O-])cc1)N1CCCc2ccccc21<mask_1:3> | 1 | 16 | 3 | 1 | 3 | CCOC(=O)/C(=N/Nc1ccccc([N+](=O)[O-])cc1)N1CCCc2ccccc21 | CCOC(=O)/C(=N/Nc1ccc([N+](=O)[O-])cc1)N1CCCc2ccccc21 | 1cc |
<|startoftext|><L>CCOC(=O)<mask_1:3>(=N/Nc1ccc([N+](=O)[O-])cc1)N1CCCc2ccccc21<mask_1:3> | 2 | 8 | 3 | /C | 3 | CCOC(=O)N/C(=N/Nc1ccc([N+](=O)[O-])cc1)N1CCCc2ccccc21 | CCOC(=O)/C(=N/Nc1ccc([N+](=O)[O-])cc1)N1CCCc2ccccc21 | N/C |
<|startoftext|><L>CCOC(=O)/C(=N/Nc1ccc([N+](=O)[O-])cc1)N1CCCc2cc<mask_1:7>c21<mask_1:7> | 2 | 47 | 7 | cc | 7 | CCOC(=O)/C(=N/Nc1ccc([N+](=O)[O-])cc1)N1CCCc2ccc(OCC)cc21 | CCOC(=O)/C(=N/Nc1ccc([N+](=O)[O-])cc1)N1CCCc2ccccc21 | c(OCC)c |
<|startoftext|><L>CCOC(=O)/C(=N<mask_1:5>ccc([N+](=O)[O-])cc1)N1CCCc2ccccc21<mask_1:5> | 4 | 13 | 5 | /Nc1 | 5 | CCOC(=O)/C(=N/NNc1ccc([N+](=O)[O-])cc1)N1CCCc2ccccc21 | CCOC(=O)/C(=N/Nc1ccc([N+](=O)[O-])cc1)N1CCCc2ccccc21 | /NNc1 |
<|startoftext|><L>COc1cc(/N=N/c2ccc(Cl)<mask_1:1>Cl)c2)cc(CO)c1O<mask_1:1> | 2 | 21 | 1 | c( | 1 | COc1cc(/N=N/c2ccc(Cl)(Cl)c2)cc(CO)c1O | COc1cc(/N=N/c2ccc(Cl)c(Cl)c2)cc(CO)c1O | ( |
<|startoftext|><L>COc1cc<mask_1:1>/c2ccc(Cl)c(Cl)c2)cc(CO)c1O<mask_1:1> | 5 | 6 | 1 | (/N=N | 1 | COc1cc(/c2ccc(Cl)c(Cl)c2)cc(CO)c1O | COc1cc(/N=N/c2ccc(Cl)c(Cl)c2)cc(CO)c1O | ( |
<|startoftext|><L>COc1cc(/N=N/c2ccc(Cl)c(Cl)c2)c<mask_1:2>O)c1O<mask_1:2> | 3 | 30 | 2 | c(C | 2 | COc1cc(/N=N/c2ccc(Cl)c(Cl)c2)cc(O)c1O | COc1cc(/N=N/c2ccc(Cl)c(Cl)c2)cc(CO)c1O | c( |
<|startoftext|><L>COc1cc(/N=N/c2ccc(<mask_1:4>c(Cl)c2)cc(CO)c1O<mask_1:4> | 3 | 18 | 4 | Cl) | 4 | COc1cc(/N=N/c2ccc(C#N)c(Cl)c2)cc(CO)c1O | COc1cc(/N=N/c2ccc(Cl)c(Cl)c2)cc(CO)c1O | C#N) |
<|startoftext|><L>COc1cc(/N<mask_1:5>2ccc(Cl)c(Cl)c2)cc(CO)c1O<mask_1:5> | 4 | 9 | 5 | =N/c | 5 | COc1cc(/N=N/Nc2ccc(Cl)c(Cl)c2)cc(CO)c1O | COc1cc(/N=N/c2ccc(Cl)c(Cl)c2)cc(CO)c1O | =N/Nc |
<|startoftext|><L>COc1cc(/<mask_1:3>N/c2ccc(Cl)c(Cl)c2)cc(CO)c1O<mask_1:3> | 2 | 8 | 3 | N= | 3 | COc1cc(/C=NN/c2ccc(Cl)c(Cl)c2)cc(CO)c1O | COc1cc(/N=N/c2ccc(Cl)c(Cl)c2)cc(CO)c1O | C=N |
<|startoftext|><L>COc1cc(/N=N/c2<mask_1:2>Cl)c(Cl)c2)cc(CO)c1O<mask_1:2> | 4 | 14 | 2 | ccc( | 2 | COc1cc(/N=N/c2c(Cl)c(Cl)c2)cc(CO)c1O | COc1cc(/N=N/c2ccc(Cl)c(Cl)c2)cc(CO)c1O | c( |
<|startoftext|><L>COc1cc(/N<mask_1:4>N/c2ccc(Cl)c(Cl)c2)cc(CO)c1O<mask_1:4> | 1 | 9 | 4 | = | 4 | COc1cc(/N=N/CN/c2ccc(Cl)c(Cl)c2)cc(CO)c1O | COc1cc(/N=N/c2ccc(Cl)c(Cl)c2)cc(CO)c1O | =N/C |
<|startoftext|><L>COc1cc(/N<mask_1:4>=N/c2ccc(Cl)c(Cl)c2)cc(CO)c1O<mask_1:4> | 0 | 9 | 4 | 4 | COc1cc(/N=C/C=N/c2ccc(Cl)c(Cl)c2)cc(CO)c1O | COc1cc(/N=N/c2ccc(Cl)c(Cl)c2)cc(CO)c1O | =C/C |
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<|startoftext|><L><mask_1:4>c1cc(/N=N/c2ccc(Cl)c(Cl)c2)cc(CO)c1O<mask_1:4> | 2 | 0 | 4 | CO | 4 | N#CCc1cc(/N=N/c2ccc(Cl)c(Cl)c2)cc(CO)c1O | COc1cc(/N=N/c2ccc(Cl)c(Cl)c2)cc(CO)c1O | N#CC |
<|startoftext|><L>C[C@@H](c1ccccn1)N(C)C(=O)c1cc(NC[C@@H]2CC=CC<mask_1:8>S(=O)(=O)N(C)C)c1<mask_1:8> | 6 | 45 | 8 | C2)cc( | 8 | C[C@@H](c1ccccn1)N(C)C(=O)c1cc(NC[C@@H]2CC=CCC2)cc(NCS(=O)(=O)N(C)C)c1 | C[C@@H](c1ccccn1)N(C)C(=O)c1cc(NC[C@@H]2CC=CCC2)cc(S(=O)(=O)N(C)C)c1 | C2)cc(NC |
<|startoftext|><L>C[C@@H](c1ccc<mask_1:8>1)N(C)C(=O)c1cc(NC[C@@H]2CC=CCC2)cc(S(=O)(=O)N(C)C)c1<mask_1:8> | 2 | 13 | 8 | cn | 8 | C[C@@H](c1ccc(C(C)C)o1)N(C)C(=O)c1cc(NC[C@@H]2CC=CCC2)cc(S(=O)(=O)N(C)C)c1 | C[C@@H](c1ccccn1)N(C)C(=O)c1cc(NC[C@@H]2CC=CCC2)cc(S(=O)(=O)N(C)C)c1 | (C(C)C)o |
<|startoftext|><L>C[C@@H](c1ccccn1)N(C)C(=O)c1cc(NC[C@@H]2CC=CCC2)cc(S<mask_1:6>=O)N(C)C)c1<mask_1:6> | 5 | 52 | 6 | (=O)( | 6 | C[C@@H](c1ccccn1)N(C)C(=O)c1cc(NC[C@@H]2CC=CCC2)cc(S(=O)(N=O)N(C)C)c1 | C[C@@H](c1ccccn1)N(C)C(=O)c1cc(NC[C@@H]2CC=CCC2)cc(S(=O)(=O)N(C)C)c1 | (=O)(N |
<|startoftext|><L>C[C@@H](c1ccccn1)N(C)C(=O)c1cc(NC[C@@H]2CC=CCC2)cc(S(=O)(=O<mask_1:9>c1<mask_1:9> | 7 | 59 | 9 | )N(C)C) | 10 | C[C@@H](c1ccccn1)N(C)C(=O)c1cc(NC[C@@H]2CC=CCC2)cc(S(=O)(=O)N2CCOCC2)c1 | C[C@@H](c1ccccn1)N(C)C(=O)c1cc(NC[C@@H]2CC=CCC2)cc(S(=O)(=O)N(C)C)c1 | )N2CCOCC2) |
<|startoftext|><L>C[C@@H](c1ccccn1)N(C)C(=O)c1cc(NC[C@@H]2CC=CCC<mask_1:6>(=O)N(C)C)c1<mask_1:6> | 10 | 46 | 6 | 2)cc(S(=O) | 6 | C[C@@H](c1ccccn1)N(C)C(=O)c1cc(NC[C@@H]2CC=CCC2)cc(C(=O)N(C)C)c1 | C[C@@H](c1ccccn1)N(C)C(=O)c1cc(NC[C@@H]2CC=CCC2)cc(S(=O)(=O)N(C)C)c1 | 2)cc(C |
<|startoftext|><L>C[C@@H](c1ccccn1)N(C)C(=O)c1cc(NC[C<mask_1:6>CC2)cc(S(=O)(=O)N(C)C)c1<mask_1:6> | 9 | 35 | 6 | @@H]2CC=C | 6 | C[C@@H](c1ccccn1)N(C)C(=O)c1cc(NC[C@H]2CCCC2)cc(S(=O)(=O)N(C)C)c1 | C[C@@H](c1ccccn1)N(C)C(=O)c1cc(NC[C@@H]2CC=CCC2)cc(S(=O)(=O)N(C)C)c1 | @H]2CC |
<|startoftext|><L>C[C@@H](c1ccccn1)N(C)C(=O)c1cc(NC[C@@H]2CC=CCC2)cc(S(=O)(=<mask_1:9>)c1<mask_1:9> | 7 | 58 | 9 | O)N(C)C | 9 | C[C@@H](c1ccccn1)N(C)C(=O)c1cc(NC[C@@H]2CC=CCC2)cc(S(=O)(=O)N2CCCC2)c1 | C[C@@H](c1ccccn1)N(C)C(=O)c1cc(NC[C@@H]2CC=CCC2)cc(S(=O)(=O)N(C)C)c1 | O)N2CCCC2 |
<|startoftext|><L>C[C@@H](c1ccccn1)N(C)C(=O<mask_1:4>cc(NC[C@@H]2CC=CCC2)cc(S(=O)(=O)N(C)C)c1<mask_1:4> | 3 | 25 | 4 | )c1 | 4 | C[C@@H](c1ccccn1)N(C)C(=O)Nc1cc(NC[C@@H]2CC=CCC2)cc(S(=O)(=O)N(C)C)c1 | C[C@@H](c1ccccn1)N(C)C(=O)c1cc(NC[C@@H]2CC=CCC2)cc(S(=O)(=O)N(C)C)c1 | )Nc1 |
<|startoftext|><L>C[C@@H](c1ccc<mask_1:7>=O)c1cc(NC[C@@H]2CC=CCC2)cc(S(=O)(=O)N(C)C)c1<mask_1:7> | 10 | 13 | 7 | cn1)N(C)C( | 7 | C[C@@H](c1ccccc1)NC(=O)c1cc(NC[C@@H]2CC=CCC2)cc(S(=O)(=O)N(C)C)c1 | C[C@@H](c1ccccn1)N(C)C(=O)c1cc(NC[C@@H]2CC=CCC2)cc(S(=O)(=O)N(C)C)c1 | cc1)NC( |
<|startoftext|><L>C[C@@H](c1ccccn1)N(C)C(=O)c1cc(NC[C@@H]2CC=CCC2)cc<mask_1:6>O)(=O)N(C)C)c1<mask_1:6> | 4 | 50 | 6 | (S(= | 6 | C[C@@H](c1ccccn1)N(C)C(=O)c1cc(NC[C@@H]2CC=CCC2)cc(CNS(=O)(=O)N(C)C)c1 | C[C@@H](c1ccccn1)N(C)C(=O)c1cc(NC[C@@H]2CC=CCC2)cc(S(=O)(=O)N(C)C)c1 | (CNS(= |
<|startoftext|><L>CCCn1cc(CN2<mask_1:4>@H](c3cc(O)nc(C)n3)C2)cn1<mask_1:4> | 5 | 11 | 4 | CCO[C | 4 | CCCn1cc(CN2CC[C@H](c3cc(O)nc(C)n3)C2)cn1 | CCCn1cc(CN2CCO[C@H](c3cc(O)nc(C)n3)C2)cn1 | CC[C |
<|startoftext|><L>CCCn1cc(CN2CCO<mask_1:5>](c3cc(O)nc(C)n3)C2)cn1<mask_1:5> | 4 | 14 | 5 | [C@H | 5 | CCCn1cc(CN2CCO[C@@H](c3cc(O)nc(C)n3)C2)cn1 | CCCn1cc(CN2CCO[C@H](c3cc(O)nc(C)n3)C2)cn1 | [C@@H |
<|startoftext|><L>CCCn1cc(CN2CCO[C@H](<mask_1:5>3cc(O)nc(C)n3)C2)cn1<mask_1:5> | 1 | 20 | 5 | c | 5 | CCCn1cc(CN2CCO[C@H](CCCNc3cc(O)nc(C)n3)C2)cn1 | CCCn1cc(CN2CCO[C@H](c3cc(O)nc(C)n3)C2)cn1 | CCCNc |
<|startoftext|><L><mask_1:4>CCCn1cc(CN2CCO[C@H](c3cc(O)nc(C)n3)C2)cn1<mask_1:4> | 0 | 0 | 4 | 4 | CCOCCCCn1cc(CN2CCO[C@H](c3cc(O)nc(C)n3)C2)cn1 | CCCn1cc(CN2CCO[C@H](c3cc(O)nc(C)n3)C2)cn1 | CCOC |
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<|startoftext|><L>CCCn1cc(C<mask_1:4>C@H](c3cc(O)nc(C)n3)C2)cn1<mask_1:4> | 6 | 9 | 4 | N2CCO[ | 4 | CCCn1cc(CN2C[C@H](c3cc(O)nc(C)n3)C2)cn1 | CCCn1cc(CN2CCO[C@H](c3cc(O)nc(C)n3)C2)cn1 | N2C[ |
<|startoftext|><L>CCCn1cc(CN2<mask_1:5>CCO[C@H](c3cc(O)nc(C)n3)C2)cn1<mask_1:5> | 0 | 11 | 5 | 5 | CCCn1cc(CN2C(=O)CCO[C@H](c3cc(O)nc(C)n3)C2)cn1 | CCCn1cc(CN2CCO[C@H](c3cc(O)nc(C)n3)C2)cn1 | C(=O) |
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<|startoftext|><L>CCCn1cc(CN2CCO[C@H](<mask_1:4>c(O)nc(C)n3)C2)cn1<mask_1:4> | 3 | 20 | 4 | c3c | 4 | CCCn1cc(CN2CCO[C@H](Cc3cc(O)nc(C)n3)C2)cn1 | CCCn1cc(CN2CCO[C@H](c3cc(O)nc(C)n3)C2)cn1 | Cc3c |
<|startoftext|><L>CCCn1cc(CN2CCO[C@H](c3cc(O)nc(C)n<mask_1:6>)cn1<mask_1:6> | 4 | 33 | 6 | 3)C2 | 6 | CCCn1cc(CN2CCO[C@H](c3cc(O)nc(C)n3)C2=O)cn1 | CCCn1cc(CN2CCO[C@H](c3cc(O)nc(C)n3)C2)cn1 | 3)C2=O |
<|startoftext|><L>CCCn1cc(CN<mask_1:5>CO[C@H](c3cc(O)nc(C)n3)C2)cn1<mask_1:5> | 2 | 10 | 5 | 2C | 5 | CCCn1cc(CN(C)C2CO[C@H](c3cc(O)nc(C)n3)C2)cn1 | CCCn1cc(CN2CCO[C@H](c3cc(O)nc(C)n3)C2)cn1 | (C)C2 |
<|startoftext|><L>CCCn1cc(<mask_1:3>[C@H](c3cc(O)nc(C)n3)C2)cn1<mask_1:3> | 6 | 8 | 3 | CN2CCO | 3 | CCCn1cc(N2C[C@H](c3cc(O)nc(C)n3)C2)cn1 | CCCn1cc(CN2CCO[C@H](c3cc(O)nc(C)n3)C2)cn1 | N2C |
<|startoftext|><L>C[C@H](Oc1c<mask_1:3>cc2ccccc2c1)C(=O)NCc1ccc(N2CCOCC2)cc1<mask_1:3> | 0 | 11 | 3 | 3 | C[C@H](Oc1c(F)cc2ccccc2c1)C(=O)NCc1ccc(N2CCOCC2)cc1 | C[C@H](Oc1ccc2ccccc2c1)C(=O)NCc1ccc(N2CCOCC2)cc1 | (F) |
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<|startoftext|><L>C[C@H](Oc1ccc2ccccc2c1)C(=O)NCc1ccc(N2CCOCC2<mask_1:2>1<mask_1:2> | 3 | 44 | 2 | )cc | 3 | C[C@H](Oc1ccc2ccccc2c1)C(=O)NCc1ccc(N2CCOCC2)cc1 | C[C@H](Oc1ccc2ccccc2c1)C(=O)NCc1ccc(N2CCOCC2)cc1 | )cc |
<|startoftext|><L>C[C@H](Oc1ccc2ccccc2c1)C(=O)NC<mask_1:5>ccc(N2CCOCC2)cc1<mask_1:5> | 2 | 30 | 5 | c1 | 5 | C[C@H](Oc1ccc2ccccc2c1)C(=O)NCCSCc1ccc(N2CCOCC2)cc1 | C[C@H](Oc1ccc2ccccc2c1)C(=O)NCc1ccc(N2CCOCC2)cc1 | CSCc1 |
<|startoftext|><L>C[C@H](Oc1ccc2ccccc2c1<mask_1:3>(=O)NCc1ccc(N2CCOCC2)cc1<mask_1:3> | 2 | 22 | 3 | )C | 3 | C[C@H](Oc1ccc2ccccc2c1)CC(=O)NCc1ccc(N2CCOCC2)cc1 | C[C@H](Oc1ccc2ccccc2c1)C(=O)NCc1ccc(N2CCOCC2)cc1 | )CC |
<|startoftext|><L>C[C@H](Oc1ccc2ccccc2c1)C(=O)NC<mask_1:4>1ccc(N2CCOCC2)cc1<mask_1:4> | 1 | 30 | 4 | c | 4 | C[C@H](Oc1ccc2ccccc2c1)C(=O)NCCSCc1ccc(N2CCOCC2)cc1 | C[C@H](Oc1ccc2ccccc2c1)C(=O)NCc1ccc(N2CCOCC2)cc1 | CSCc |
<|startoftext|><L>C[C@H](Oc1ccc2ccccc2c1)C(=O)N<mask_1:5>Cc1ccc(N2CCOCC2)cc1<mask_1:5> | 0 | 29 | 5 | 5 | C[C@H](Oc1ccc2ccccc2c1)C(=O)NC(=S)Cc1ccc(N2CCOCC2)cc1 | C[C@H](Oc1ccc2ccccc2c1)C(=O)NCc1ccc(N2CCOCC2)cc1 | C(=S) |
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<|startoftext|><L>C[C@H](Oc1ccc2c<mask_1:6>c2c1)C(=O)NCc1ccc(N2CCOCC2)cc1<mask_1:6> | 3 | 15 | 6 | ccc | 6 | C[C@H](Oc1ccc2ccc(F)cc2c1)C(=O)NCc1ccc(N2CCOCC2)cc1 | C[C@H](Oc1ccc2ccccc2c1)C(=O)NCc1ccc(N2CCOCC2)cc1 | cc(F)c |
<|startoftext|><L><mask_1:6>@H](Oc1ccc2ccccc2c1)C(=O)NCc1ccc(N2CCOCC2)cc1<mask_1:6> | 3 | 0 | 6 | C[C | 6 | CSCC[C@H](Oc1ccc2ccccc2c1)C(=O)NCc1ccc(N2CCOCC2)cc1 | C[C@H](Oc1ccc2ccccc2c1)C(=O)NCc1ccc(N2CCOCC2)cc1 | CSCC[C |
<|startoftext|><L>C[C@H](Oc1ccc2ccccc2c1)C(<mask_1:7>O)NCc1ccc(N2CCOCC2)cc1<mask_1:7> | 1 | 25 | 7 | = | 7 | C[C@H](Oc1ccc2ccccc2c1)C(=O)NC(=O)NCc1ccc(N2CCOCC2)cc1 | C[C@H](Oc1ccc2ccccc2c1)C(=O)NCc1ccc(N2CCOCC2)cc1 | =O)NC(= |
<|startoftext|><L>C[C@H](Oc1ccc2ccccc2c1)C<mask_1:7>Cc1ccc(N2CCOCC2)cc1<mask_1:7> | 5 | 24 | 7 | (=O)N | 7 | C[C@H](Oc1ccc2ccccc2c1)C(=O)NCCCc1ccc(N2CCOCC2)cc1 | C[C@H](Oc1ccc2ccccc2c1)C(=O)NCc1ccc(N2CCOCC2)cc1 | (=O)NCC |
<|startoftext|><L>N#Cc1cccnc1OC1CCN(C(=O)<mask_1:4>c2ccccc2)CC1<mask_1:4> | 3 | 23 | 4 | CCC | 4 | N#Cc1cccnc1OC1CCN(C(=O)CCCOc2ccccc2)CC1 | N#Cc1cccnc1OC1CCN(C(=O)CCCc2ccccc2)CC1 | CCCO |
<|startoftext|><L>N#Cc1cccnc1OC1C<mask_1:2>CN(C(=O)CCCc2ccccc2)CC1<mask_1:2> | 0 | 15 | 2 | 2 | N#Cc1cccnc1OC1CCCCN(C(=O)CCCc2ccccc2)CC1 | N#Cc1cccnc1OC1CCN(C(=O)CCCc2ccccc2)CC1 | CC |
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<|startoftext|><L>N#Cc1cccnc1OC1CCN(C(=O)CC<mask_1:2>c2ccccc2)CC1<mask_1:2> | 1 | 25 | 2 | C | 2 | N#Cc1cccnc1OC1CCN(C(=O)CCCOc2ccccc2)CC1 | N#Cc1cccnc1OC1CCN(C(=O)CCCc2ccccc2)CC1 | CO |
<|startoftext|><L><mask_1:5>#Cc1cccnc1OC1CCN(C(=O)CCCc2ccccc2)CC1<mask_1:5> | 1 | 0 | 5 | N | 5 | C(C)C#Cc1cccnc1OC1CCN(C(=O)CCCc2ccccc2)CC1 | N#Cc1cccnc1OC1CCN(C(=O)CCCc2ccccc2)CC1 | C(C)C |
<|startoftext|><L>N#Cc1cccnc1OC1CCN<mask_1:4>(C(=O)CCCc2ccccc2)CC1<mask_1:4> | 0 | 17 | 4 | 4 | N#Cc1cccnc1OC1CCN(C)N(C(=O)CCCc2ccccc2)CC1 | N#Cc1cccnc1OC1CCN(C(=O)CCCc2ccccc2)CC1 | (C)N |
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<|startoftext|><L>N#Cc1cccnc1OC1C<mask_1:2>C(=O)CCCc2ccccc2)CC1<mask_1:2> | 3 | 15 | 2 | CN( | 2 | N#Cc1cccnc1OC1CN(C(=O)CCCc2ccccc2)CC1 | N#Cc1cccnc1OC1CCN(C(=O)CCCc2ccccc2)CC1 | N( |
<|startoftext|><L>N#C<mask_1:5>cccnc1OC1CCN(C(=O)CCCc2ccccc2)CC1<mask_1:5> | 2 | 3 | 5 | c1 | 5 | N#CCCOc1cccnc1OC1CCN(C(=O)CCCc2ccccc2)CC1 | N#Cc1cccnc1OC1CCN(C(=O)CCCc2ccccc2)CC1 | CCOc1 |
<|startoftext|><L>N#Cc1cccnc1OC1CCN(C(=O)CCCc2ccccc<mask_1:2>1<mask_1:2> | 4 | 33 | 2 | 2)CC | 2 | N#Cc1cccnc1OC1CCN(C(=O)CCCc2ccccc2)1 | N#Cc1cccnc1OC1CCN(C(=O)CCCc2ccccc2)CC1 | 2) |
<|startoftext|><L>N#C<mask_1:5>cccnc1OC1CCN(C(=O)CCCc2ccccc2)CC1<mask_1:5> | 2 | 3 | 5 | c1 | 5 | N#CCCOc1cccnc1OC1CCN(C(=O)CCCc2ccccc2)CC1 | N#Cc1cccnc1OC1CCN(C(=O)CCCc2ccccc2)CC1 | CCOc1 |
<|startoftext|><L>N#Cc1cccnc1OC1C<mask_1:1>(C(=O)CCCc2ccccc2)CC1<mask_1:1> | 2 | 15 | 1 | CN | 1 | N#Cc1cccnc1OC1CN(C(=O)CCCc2ccccc2)CC1 | N#Cc1cccnc1OC1CCN(C(=O)CCCc2ccccc2)CC1 | N |
<|startoftext|><L>Cn1nccc1<mask_1:6>[C@@H]1OCCC[C@H]1CNC(=O)[C@H]1CCN(C(=O)c2ccccc2)C1<mask_1:6> | 0 | 8 | 6 | 6 | Cn1nccc1C(=O)N[C@@H]1OCCC[C@H]1CNC(=O)[C@H]1CCN(C(=O)c2ccccc2)C1 | Cn1nccc1[C@@H]1OCCC[C@H]1CNC(=O)[C@H]1CCN(C(=O)c2ccccc2)C1 | C(=O)N |
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<|startoftext|><L>C<mask_1:5>nccc1[C@@H]1OCCC[C@H]1CNC(=O)[C@H]1CCN(C(=O)c2ccccc2)C1<mask_1:5> | 2 | 1 | 5 | n1 | 5 | CCOc1cnccc1[C@@H]1OCCC[C@H]1CNC(=O)[C@H]1CCN(C(=O)c2ccccc2)C1 | Cn1nccc1[C@@H]1OCCC[C@H]1CNC(=O)[C@H]1CCN(C(=O)c2ccccc2)C1 | COc1c |
<|startoftext|><L>Cn1nccc1<mask_1:2>OCCC[C@H]1CNC(=O)[C@H]1CCN(C(=O)c2ccccc2)C1<mask_1:2> | 7 | 8 | 2 | [C@@H]1 | 2 | Cn1nccc1C1OCCC[C@H]1CNC(=O)[C@H]1CCN(C(=O)c2ccccc2)C1 | Cn1nccc1[C@@H]1OCCC[C@H]1CNC(=O)[C@H]1CCN(C(=O)c2ccccc2)C1 | C1 |
<|startoftext|><L>Cn1nccc1[C@@H]1<mask_1:7>]1CNC(=O)[C@H]1CCN(C(=O)c2ccccc2)C1<mask_1:7> | 8 | 15 | 7 | OCCC[C@H | 7 | Cn1nccc1[C@@H]1OCC[C@H]1CNC(=O)[C@H]1CCN(C(=O)c2ccccc2)C1 | Cn1nccc1[C@@H]1OCCC[C@H]1CNC(=O)[C@H]1CCN(C(=O)c2ccccc2)C1 | OCC[C@H |
<|startoftext|><L>Cn1nccc1[C@@H]1OCCC[C@H]1CNC(=<mask_1:7>CCN(C(=O)c2ccccc2)C1<mask_1:7> | 8 | 30 | 7 | O)[C@H]1 | 8 | Cn1nccc1[C@@H]1OCCC[C@H]1CNC(=O)[C@H]1CCN(C(=O)c2ccccc2)C1 | Cn1nccc1[C@@H]1OCCC[C@H]1CNC(=O)[C@H]1CCN(C(=O)c2ccccc2)C1 | O)[C@H]1 |
<|startoftext|><L>Cn1nccc<mask_1:8>H]1OCCC[C@H]1CNC(=O)[C@H]1CCN(C(=O)c2ccccc2)C1<mask_1:8> | 5 | 7 | 8 | 1[C@@ | 8 | Cn1nccc1CNC[C@@H]1OCCC[C@H]1CNC(=O)[C@H]1CCN(C(=O)c2ccccc2)C1 | Cn1nccc1[C@@H]1OCCC[C@H]1CNC(=O)[C@H]1CCN(C(=O)c2ccccc2)C1 | 1CNC[C@@ |
<|startoftext|><L>Cn1nccc1[C@@H]1OCCC[C@H]1CNC(=O)[C@H]<mask_1:4>CCN(C(=O)c2ccccc2)C1<mask_1:4> | 1 | 37 | 4 | 1 | 4 | Cn1nccc1[C@@H]1OCCC[C@H]1CNC(=O)[C@H]1CC=CCN(C(=O)c2ccccc2)C1 | Cn1nccc1[C@@H]1OCCC[C@H]1CNC(=O)[C@H]1CCN(C(=O)c2ccccc2)C1 | 1CC= |
<|startoftext|><L>Cn1nccc1[C@@<mask_1:2>CC[C@H]1CNC(=O)[C@H]1CCN(C(=O)c2ccccc2)C1<mask_1:2> | 5 | 12 | 2 | H]1OC | 2 | Cn1nccc1[C@@]1CC[C@H]1CNC(=O)[C@H]1CCN(C(=O)c2ccccc2)C1 | Cn1nccc1[C@@H]1OCCC[C@H]1CNC(=O)[C@H]1CCN(C(=O)c2ccccc2)C1 | ]1 |
<|startoftext|><L><mask_1:2>n1nccc1[C@@H]1OCCC[C@H]1CNC(=O)[C@H]1CCN(C(=O)c2ccccc2)C1<mask_1:2> | 1 | 0 | 2 | C | 2 | CCn1nccc1[C@@H]1OCCC[C@H]1CNC(=O)[C@H]1CCN(C(=O)c2ccccc2)C1 | Cn1nccc1[C@@H]1OCCC[C@H]1CNC(=O)[C@H]1CCN(C(=O)c2ccccc2)C1 | CC |
<|startoftext|><L>Cn1nccc1[C@@H]1<mask_1:7>]1CNC(=O)[C@H]1CCN(C(=O)c2ccccc2)C1<mask_1:7> | 8 | 15 | 7 | OCCC[C@H | 7 | Cn1nccc1[C@@H]1OCC[C@H]1CNC(=O)[C@H]1CCN(C(=O)c2ccccc2)C1 | Cn1nccc1[C@@H]1OCCC[C@H]1CNC(=O)[C@H]1CCN(C(=O)c2ccccc2)C1 | OCC[C@H |