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afferent

To investigate the role of metabo - and mechanosensitive group III/IV muscle afferents in limiting the intramuscular metabolic perturbation during whole body endurance exercise, eight subjects performed 5 km cycling time trials under control conditions (CTRL) and with lumbar intrathecal fentanyl impairing lower limb muscle afferent feedback (FENT).

Significantly more afferent connections were detected for the TD patients for tremor -periods and non- tremor -periods combined as well as for only tremor periods.

afferent

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retire

Thirty-five TSH values were obtained 2-7 weeks postoperatively and 101 values were obtained 2-8 weeks post L-T4 withdrawal.

The figures are startling: the number of NHS staff applying to retire has surged by a quarter since 2012.

withdrawal

abbreviations

HP

Tonsillar human papillomavirus (HPV) status was determined by PCR.

Our aims were to determine the prevalence of HP in a selected group of CD patients with quiescent disease, and to assess the influence of its eradication on disease activity and endoscopic and laboratory activity measures.

human papillomavirus

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L2/3 pyramidal neurons

We analyzed the CT findings after LPN, including postoperative changes, tumor recurrence, and complications.

Acute RA treatment increases spontaneous inhibitory synaptic transmission in L2/3 pyramidal neurons of the somatosensory cortex, and this effect requires expression of RA's receptor RARα both pre- and post-synaptically.

LPN

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Pokémon GO

Serum pepsinogen (PG) I level and PG I / II ratio decreased significantly according to the severity of atrophy in HD patients and positively significantly correlated with both ghrelin levels.

Pokémon GO is a location -based augmented reality game.

PG

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breastfeeding

Nursing ancestry now easier to trace as RCN records are published online

In all, 54.2% of infants and 25.2% of toddlers were breastfeeding.

Nursing

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C2 deficiency

3) type II C2 deficiency is caused by a different, as yet uncharacterized, molecular genetic defect.

The significance of this association is controversial, though the association of C2 deficiency with certain histocompatibility antigens suggests possible linkage to immune response genes.

type II C2 deficiency

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uptake

N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A

Uranium uptake rates follow first order kinetics over a range encompassing most environmental concentrations.

uptake

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colonoscopy

A slave robot was developed to hold the colonoscopy and its knob, and perform insertion, rotation, and two tilting motions of colonoscope.

A large - volume bowel preparation regimen finished on the day of colonoscopy as close as 3 hours before the procedure result s in no increase in GRV or decrease in gastric pH.

colonoscopy

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muscle weakness

The CK increase persisted, however, and she developed progressive muscular weakness and muscular atrophy.

All patients had muscular dystrophy or muscle weakness, mental retardation, congenital adrenal hypoplasia, and glycerol kinase deficiency.

muscular weakness

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murine

Isometric contraction measurements and patch clamp technique were used to verify TASK conductance in murine myometrium.

In this manuscript, we discuss the different approaches used to demonstrate the presence of PSCs in the murine adult pituitary, from marker analyses to genetic tracing.

murine

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PPH

Dysfunction in the nitric oxide (NO) pathway plays a key role in the pulmonary hypertension disease process, including in WHO Groups 2 and 3 PH. PH is associated with endothelial dysfunction, impaired synthesis of NO, and insufficient stimulation of the NO-soluble guanylate cyclase (sGC)-cyclic guanosine monophosphate (cGMP) pathway, which reduces cGMP production.

CONCLUSION: The magnitude of the association with PPH, the increase of association with increasing duration of use, and the specificity for fenfluramines are consistent with previous studies indicating that fenfluramines are causally related to PPH.

PH

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DHA

Enhancement of docosahexaenoic acid synthesis by manipulation of antioxidant capacity and prevention of oxidative damage in Schizochytrium sp

RT-qPCR confirmed the time dependent effect of DHA on the expression of these differentially expressed genes.

docosahexaenoic acid

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TCD

12% of unrelated male patients carry deletions of the partially cloned CHM gene.

Moreover, in 71/104 non-TCD chromosomes, the haplotype at six marker loci is different from those seen in any of the 76 TCD chromosomes.

CHM

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occlusion

Long and hard objects cannot pass through the pylorus, and may cause obstruction, ulceration, bleeding and perforation.

Ischemic indices calculated from each lead showed statistically significant (p < 0.05) increase within 2 min of occlusion compared to baseline.

obstruction

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Mitochondrion

Alterations in oxidative stress and glutathione - dependent redox-homeostasis were more pronounced in mitochondria compared to extra - mitochondrial cellular compartments.

The Mitochondrion of Euglena gracilis

mitochondria

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cell

After the removal of the statistical effect of age, the difference in REC between CLL and control group remained statistically significant (F=19.732; p<0.01; eta(2)=0.287).

Tuning cell adhesive properties via layer-by-layer assembly of chitosan and alginate

CLL

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ischemic

The ischemic transition region may provide information on pathomechanical composition and severity of myocardial ischemia.

We prospectively performed continuous ambulatory ECG monitoring on 25 patients undergoing 5-FU infusion for treatment of solid tumors in order to assess the incidence of ischemic ST changes.

ischemic

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TEM

Emodin or UA can relieve pathogenic changes in epithelial cells and muscle cells in gallbladder of guinea pig with cholesterol calculus by microscope and transmission electron microscope.

PCB concentrations in the air (pg/m(3)) ranged from ~1-10 (TEM), ~1-40 (STG) and 4-30 (CON).

transmission electron microscope

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vehicle

3) vehicle without T3 (T3 negative) for 8 weeks.

For HMCR, the source contributions of soil dust, coal combustion, cement dust, vehicle, and secondary sources are 1.0 × 10(-4), 3.7 × 10(-5), 2.7 × 10(-6), 1.6 × 10(-6) and 1.9 × 10(-9), respectively.

vehicle

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thymic lymphomas

Thus, PRAD1 is an excellent candidate " BCL1 oncogene. " Its overexpression may be a key consequence of rearrangement of the BCL1 vicinity in B-cell neoplasms and a unifying pathogenetic feature in centrocytic lymphoma.

The majority of mutant mice rapidly develop thymic lymphomas and die before 4 months of age.

centrocytic lymphoma

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As

A 60-year-old female presented to the emergency department with physical examination findings consistent with severe cellulitis and associated sepsis.

Concentrations of Al, As, Cd, Co, Cr, Cu, Fe, Mn, Mo, Ni, Pb, V and Zn were measured in both soils (as pseudo-total) and aerial plant tissues.

associated sepsis

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dietary sodium chloride

Furthermore, salt entry into the chloroplast stroma may be critical for grana formation and photosystem II activity in halophytes but not in glycophytes.

Intravenous infusion of the ganglionic blocker hexamethonium resulted in a rapid decline in MAP that eliminated the dietary sodium chloride-induced increase in MAP in both groups.

salt

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CSCs

Colony and spheroid formation assays, as well as western blotting analysis of lung CSC protein markers were employed to determine the CSC -like phenotypes of H460 lung cancer cells after treatment with RM at non-toxic concentrations.

These data provide insights into the plasticity of CSCs and their potential as a therapeutic target in human colorectal cancer.

CSC

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objectives

The objective of this study is to understand the safety partnership preferences of patients and their families.

User-defined clinical objectives are employed for setting up a multi-objective problem.

objective

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CHS

We show herein that CTLA-4 is present in enlarged, abnormal vesicles in CHS T cells and is not properly expressed at the cell surface after T cell activation, whereas its surface expression is not impaired.

It is therefore proposed that the defective surface expression of CTLA-4 by CHS T cells is involved in the generation of lymphoproliferative disease.

CHS

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cell types

Limits for radiation exposures are legally regulated; however, current radiation protection policy does not explicitly acknowledge that biological, cellular and molecular effects of low doses and low dose rates of radiation differ from effects induced by medium and high dose radiation exposures.

In addition to iPSCs, several other cell types have also been generated by master transcription factor (TF)-mediated transdifferentiation.

cellular

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TTC

Correlation analysis showed that IL-2 was positively correlated with total cholesterol (TC), LDL-c, and genotype (r = 0.542, 0.410, 0.598, P < 0.05) and negatively correlated with HDL-c (r = -0.352, P < 0.05).

Methods and results: Our institutional database constituted a collective of 84 patients diagnosed with TTC between 2003 and 2015.

TC

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Laser capture micro-dissection

The choice between routes of LMD is largely driven not only by the myocardial pathology but also by the nature and physicochemical properties of the therapeutic agents.

Laser capture micro-dissection was used to take 25000 μm(2) subsamples or spots.

LMD

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cholestasis

The liver damage was characterized according to hepatocellular, cholestatic, and mixed laboratory criteria and to histologic criteria when available.

This observation demonstrates that prolonged cholestasis can follow troleandomycin-induced acute hepatitis.

cholestatic

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population-based

Population based follow-up.

The present population-based, longitudinal study revealed inverse associations between sex hormones and depressive symptoms.

Population based follow-up

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VO2

Collectively, our results demonstrate that miR-125b-5p plays an important role in the repression of brite adipocyte function by modulating oxygen consumption and mitochondrial gene expression.

Low PSAP was associated with a significantly lower peak VO2 (mean (SD), 35 (2) % predicted) compared to high PSAP response (peak VO2 45 (3) % predicted), p=0.045.

oxygen consumption

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Wearing Experience

Our experience supported the use of a traditional lecture over a digital game module.

Principal components analysis demonstrated the existence of three subscales (Discomfort, General Wearing Experience, and Function).

experience

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hs-CRP

The areas under the curve of CRP for SBP based on the PMN count ≥ 250/mm(3) and cultured ascites was 0.94 (CI 95%: 0.90 to 0.96) and 0.85 (CI 95%: 0.84 to 0.92), respectively (P < 0.001).

However, there was no significant difference in the mean hs-CRP values in patients with or without mortality.

CRP

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burn

However there was a significant difference in the mean frequency of burning, aching, soreness and lump sensation (p value<0.05) in patients with vitamin D deficiency compared to those with no vitamin D deficiency.

One burn site was treated with each of four different CHP concentrations, from 0.25 per cent to 2 per cent, their vehicle, and 1 per cent silver sulphadiazine (AgSD) cream, an antimicrobial agent frequently used for topical treatment of burn wounds.

burning

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chronic renal failure

Hemodialysis via the internal jugular vein (IJV) has been widely used for patients with end stage renal disease (ESRD) patients, as they have a higher risk of arterial diseases.

Two patients with similar clinical features are presented: both patients had chronic renal failure, on hemodialysis for many years but recently begun on a high-flux dialyzer; both had been receiving a carbidopa/levodopa preparation; and both had the onset of hallucinosis and recurrent seizures, which were refractory to anticonvulsants.

end stage renal disease

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heads

Furthermore, moving from these data, the total dose of submicron particles deposited in the respiratory system (i.e., head, tracheobronchial and alveolar regions in different lung lobes) has been estimated.

Two other taxa yielded positives only from the heads and the remainder tested negative.

head

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rash

It demonstrated that the expressions of 174 protein spots over 1045 quantified spots were altered after uranium exposure (p<0.05).

Six patients (10.3%) had dose-limiting toxicities, of which only rash (two patients, 3.4%) occurred in more than one patient.

spots

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SEER

Using data obtained by the Surveillance, Epidemiology, and End Results (SEER) program from 2010-2012, a retrospective, population-based cohort study was conducted to investigate tumor subtype - specific differences in various characteristics, overall survival (OS) and breast cancer-specific mortality (BCSM) between males and females.

Squamous Cell Carcinoma of the Bladder: A SEER Database Analysis

Surveillance, Epidemiology, and End Results (SEER) program

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Drug-Drug Interaction

Quantifying macromolecular interactions in living cells using FRET two-hybrid assays

Characterization of the Effect of Drug-Drug Interaction on Protein Binding in Concurrent Administration of Sulfamethoxazol and Diclofenac Sodium Using Bovine Serum Albumin

interactions

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SLC1A1

Using a combination of in silico and in vitro analyses, we found that miR-101b targets the neuronal glutamate transporter SLC1A1 (also known as EAAC1 or EAAT3).

Accordingly, both mRNA and protein levels of SLC1A1 were found to be upregulated in the PFC of the FSL model.

EAAT3

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prolidase deficiency

The purpose of this study was to identify the specific metabolic brain pattern characteristic for Parkinson's disease (PD): Parkinson's disease-related pattern (PDRP), using network analysis of [18F]-fluorodeoxyglucose positron emission tomography (FDG-PET) brain images in a cohort of Slovenian PD patients.

Our results indicate that the severe form of prolidase deficiency is caused by multiple PEPD alleles.

PD

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genus

Genus -level analysis showed differential abundance of Prevotella and Faecalibacterium (higher in HCV patients) vs. Ruminococcus and Clostridium (healthy group), indicating that the higher abundance of Bacteroidetes in HCV patients is most likely due to Prevotella overabundance.

Lipoptilocnema Townsend is a small genus of Neotropical Sarcophaginae with a distinctive genitalic morphology.

Genus

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biomedical

Utilization Pattern and Drug Use of Traditional Chinese Medicine, Western Medicine, and Integrated Chinese-Western Medicine Treatments for Allergic Rhinitis Under the National Health Insurance Program in Taiwan

Clinical yarning is a patient -centred approach that marries Aboriginal cultural communication preferences with biomedical understandings of health and disease.

Western Medicine

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ALRTI

Use of ART containing HIV PIs has previously been associated with toxicity in subcutaneous adipose tissue (SAT), potentially contributing to the development of lipodystrophy and insulin resistance.

Three hundred and eighty-seven children hospitalized for ALRTI were enrolled.

ART

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fertility

This study is the first to show adverse effects of imidacloprid on queen bee fecundity and behavior and improves our understanding of how neonicotinoids may impair short-term colony functioning.

The target (breeding goal) trait for fertility was CFS or C-LAFS, whereas C-LA and PLA served as predictor traits.

fecundity

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SMs

Patients who underwent MVD were younger than those undergoing RF or SRS.

The results obtained can also be used to explain conflicting findings from clinical studies on the effectiveness of SMs when compared to N95s and can be input into risk-assessment models to determine the increase in infection rate resulting from deployment of PPE under less-than-ideal conditions.

SRS

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tissue growth

NUCLEAR FACTOR-Y (NF-Y) has been shown to play an important role in growth, development, and response to environmental stress.

We evaluated how nutrient enrichment (i.e., nitrogen availability) affected the growth of Fucus vesiculosus, a foundational macroalgal species in the North Atlantic rocky intertidal zone, and found that nutrient -enriched algal blades showed a significant increase in tissue growth compared to individuals grown under ambient conditions.

growth

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type 2 diabetes

Patients with COPD showed a high prevalence of hypertension (72%), dyslipidaemia (73%), obesity (41%), diabetes type 2 (39%), and sleep apnoea syndrome (30%) from mild stages of the disease (GOLD 2009).

Salivary protective factors in patients suffering from decompensated type 2 diabetes

diabetes type 2

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spiking

Laceration of a branch of the profunda femoris artery caused by a spike of the displaced lesser trochanter in an inter-trochanteric femoral fracture.

Accuracy, calculated from the recovery percentage at three spiking levels, varied from 94 to 113 %, depending on the analyte.

spike

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autistic

A prospective, open-label trial of galantamine in autistic disorder.

She was profoundly mentally retarded, autistic, and had minor dysmorphic features consistent with those of previous patients with similar deletions.

autistic disorder

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Three-dimensional

In this paper we shed new light on the 3D pharmacological properties of the 5-HT1A receptor by using a ligand-guided approach (ALiBERO) grounded in the Internal Coordinate Mechanics (ICM) docking platform.

Three-dimensional functional human neuronal networks in uncompressed low-density electrospun fiber scaffolds

3D

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hypobetalipoproteinemia

Homozygous hypobetalipoproteinemia: a disease distinct from abetalipoproproteinemia at the molecular level.

These mice should help increase our understanding of hypobetalipoproteinemia, atherogenesis, and the etiology of exencephalus and hydrocephalus.

Homozygous hypobetalipoproteinemia

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Ca

Now, more and more patients are suffering cerebral aneurysm.

In a second series, cytosolic Ca2+ activity (Fluo3 fluorescence), cell volume (forward scatter), and PS-exposure (annexin V binding) were determined by FACS analysis in erythrocytes from healthy volunteers.

cerebral aneurysm

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Hodgkin lymphoma

Our results suggest that the OsAld-Y participates in Chl accumulation, chloroplast development and plant growth by influencing the photosynthetic rate of leaves and the sugar metabolism of rice.

Diagnoses of the enrolled patients were as follows: seven (24.1%) with acute myeloid leukemia, eight (27.6%) with multiple myeloma, four (13.8%) with acute lymphoblastic leukemia, three (10.3%) with non-Hodgkin lymphoma, two (6.9%) with myelodysplastic syndromes, two (6.9%) with aplastic anemia, two (6.9%) with chronic myeloid leukemia, one (3.4%) with Hodgkin lymphoma, and one (3.4%) with plasmacytomas.

Chl

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HCV infection

The hepatitis C virus (HCV) has six major genotypes.

Hemoglobin concentrations decrease mainly as a result of ribavirin-induced hemolysis, and this anemia can be problematic in patients with HCV infection, especially those who have comorbid renal or cardiovascular disorders.

HCV