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synonyms | 160 | PMH | Future studies will be needed to elucidate the exact neuro - behavioral deficits that lead to the increase in indiscriminate responding for drug in rats with a history of perinatal ID. | 0 | 140 | 137 | Immunohistochemistry showed that mammalian target of rapamycin was expressed in PMH biopsy specimens, which may explain the reduction in PMH tumor size following treatment. | history | 167 |
term_identity | 52 | neighborhoods | The mean number of grocery stores was 3.4 ± 2.3 per neighborhood. | 1 | 69 | 56 | These risks may be amplified in low-income and minority neighborhoods due to generally higher rates of active travel or lack of safety infrastructure. | neighborhood | 64 |
label_similarity | 126 | Procedure | The chemical composition of leaf essential oils from 11 species of Piper from Panama was analyzed by a combination GC-FID and GC-MS procedures. | 0 | 9 | 0 | Procedure -related data were collected prospectively for the first 100 ablation procedures performed in our department using the STSF catheter. | GC-MS procedures | 142 |
label_similarity | 166 | COCs | Close attention must be paid to CTC characterization since neither approach tested here fully reflects the tremendous phenotypic and genetic heterogeneity present in CTCs from mCRPC patients. | 0 | 57 | 53 | Of these women, 67 were on levonorgestrel-containing COCs. | CTCs | 170 |
synonyms | 92 | TSC1 | We aimed to determine its lateralizing utility in patients with tuberous sclerosis complex (TSC). | 0 | 43 | 39 | It is due to inactivating mutations in TSC1 or TSC2. | TSC | 95 |
synonyms | 15 | AR | Progression of aortic insufficiency occurred in 38.9% (28/72). | 0 | 129 | 127 | If translation occurred less than 20% of the time, a minority disagreed that this would "significantly reduce your support for AR ". | aortic insufficiency | 35 |
label_similarity | 77 | hematological disorders | Treatment with antithrombin attenuated the puromycin aminonucleoside-induced hematological abnormalities. | 1 | 104 | 81 | Antibodies suggested to be of the IgM class were detected in all 3 patients with hematological disorders. | hematological abnormalities | 104 |
label_similarity | 57 | neurological disturbance | Each child was examined by a neuropediatrician for minor neurological dysfunctions and tested by a psychologist for cognitive development with a Kaufman Assessment Battery for Children and a Draw-a-Man Test. | 1 | 57 | 33 | In six of the probable cases the neurological disturbance consisted of an acute reversible encephalopathy usually related to the ingestion of a high dose of clioquinol over a short period. | neurological dysfunctions | 82 |
synonyms | 50 | Pneumococcal Polysaccharide Vaccine | We have previously demonstrated that experimental pneumococcal carriage enhances immunity and protects healthy adults against carriage reacquisition after rechallenge with a homologous strain. | 0 | 62 | 27 | Maternal Immunization with Pneumococcal Polysaccharide Vaccine: Persistence of Maternal Antibodies in Infants | pneumococcal | 62 |
synonyms | 12 | sarcoidosis | Hemorrhagic sarcoid pleural effusion: A rare entity | 1 | 48 | 37 | We report a case of active pulmonary sarcoidosis presenting as hemorrhagic pleural effusion requiring tissue diagnosis to rule out malignancy. | sarcoid | 19 |
label_similarity | 139 | European | Folate and vitamin B12 concentrations are associated with plasma DHA and EPA fatty acids in European adolescents: the Healthy Lifestyle in Europe by Nutrition in Adolescence (HELENA) study | 1 | 30 | 22 | Malus sylvestris, the European crab-apple fruit tree in particular, is threatened by the disappearance of its habitat and by gene flow from its domesticated relative, Malus domestica. | Europe | 145 |
label_similarity | 0 | Pelizaeus-Merzbacher disease (type II) | Pelizaeus-Merzbacher disease: detection of mutations Thr181----Pro and Leu223----Pro in the proteolipid protein gene, and prenatal diagnosis. | 1 | 132 | 94 | Patients with the classical form (type I) and the more severely affected, connatal variant of Pelizaeus-Merzbacher disease (type II) would be predicted to display mutation at the PLP locus. | Pelizaeus-Merzbacher disease | 28 |
synonyms | 52 | circulation | When an IV dose of 100 mg/kg was given to mice, the blood circulation half-life was measured to be about 4 h, and more than 90% of the NPs were cleared from the mice within 24 h via the renal and hepatobiliary systems. | 0 | 147 | 136 | To understand the infection dynamics, positive PCR samples with low Ct values were sequenced (ORF5) and the data analysis indicated the circulation of wild type virus in both groups, however wild type virus was only found in non-vaccinated animals. | blood circulation | 69 |
abbreviations | 40 | left bundle branch block | Patients with left bundle branch block (LBBB) can exhibit mechanical dyssynchrony which may contribute to heart failure; such patients may benefit from cardiac resynchronization treatment (CRT). | 1 | 56 | 32 | The most common complication is left bundle branch block (LBBB). | LBBB | 44 |
synonyms | 166 | SAB | One hundred fourteen patients (age range, 2-65 years; American Society of Anesthesiology class I-II) participated in this study, willing to be sedated and to undergo spinal anesthesia. | 0 | 163 | 160 | Infectious diseases (ID) consultation and antimicrobial stewardship intervention have been shown to improve the management of Staphylococcus aureus bacteremia (SAB). | spinal anesthesia | 183 |
label_similarity | 70 | ET-1 | Spleen CD11b cells were increased in smPparγ and further enhance d in eET-1 / smPparγ, whereas Ly-6C monocytes increased in eET-1 and smPparγ but not in eET-1 / smPparγ. | 1 | 19 | 15 | Paradoxically, ET-1 overexpression preserved endothelial function in smPparγ mice, presumably by enhancing nitric oxide through stimulation of endothelin type B receptors. | eET-1 | 75 |
synonyms | 136 | V | Age, sex, height, body mass, body mass index, and vertex-marker distanc e (DV-M) were used to predict the distance from the C7SP to the vertex (DV-C7). | 0 | 228 | 227 | Mean±SE (area under fluoride clearance curve) values were (μg F/g or ml×min): biofilm fluid - CS (472±191), EP (423±75), V (1264±279); centrifuged saliva - CS (42±7), EP (19±3), V (41±8); whole saliva - CS (68±11), EP (64±10), V (60±7). | vertex | 142 |
label_similarity | 73 | methods | The average intensity level for NCI and ACI were 1.9 ± 0.4 and 4.2 ± 0.9 METs, respectively. | 0 | 12 | 5 | Both methods that were applied for the estimation of percolation threshold provided comparable values. | METs | 77 |
synonyms | 66 | muscle weakness | The CK increase persisted, however, and she developed progressive muscular weakness and muscular atrophy. | 1 | 59 | 44 | The disease is characterized by progressive muscle weakness and sustained muscle contraction, often with a wide range of accompanying symptoms. | muscular weakness | 83 |
synonyms | 0 | AS | ASM expression level was significantly increased in HRECs isolated from diabetic compared with control donor tissue, as well as CD34(+) CACs and plasma of diabetic patients. | 0 | 100 | 98 | Previous linkage and association studies have suggested the presence of a susceptibility gene for AS close to, or within, the cytochrome P450 2D6 gene (CYP2D6, debrisoquine hydroxylase) located at chromosome 22q13.1. | ASM | 3 |
abbreviations | 23 | retinal nerve fiber layer | The thicknesses of the RNFL and GCIPL were measured via spectral-domain optic coherent tomography in all participants at baseline. | 1 | 39 | 14 | Peripapillary retinal nerve fiber layer (RNFL) thickness analysis is a subjective method of analysis of glaucomatous damage. | RNFL | 27 |
abbreviations | 36 | growth hormone | In subjects previously treated with GH, BMI was not different between UPD and deletion groups (33.0 ± 9.7 vs 33.5 ± 11.1 kg/m(2)). | 1 | 56 | 42 | The most common hormone deficiency was of growth hormone (n = 67), followed by gonadotrophin (n = 50), corticotrophin (n = 49) and thyrotrophin (n = 35). | GH | 38 |
term_identity | 75 | Osteoporosis | Teriparatide, 1-34 parathyroid hormone, is one of effective treatments for osteoporosis. | 1 | 54 | 42 | Addressing the Crisis in the Treatment of Osteoporosis: A Path Forward | osteoporosis | 87 |
abbreviations | 97 | LMS | Clinical evaluation of a surgical fixation technique featuring combined use of pedicle screw and lateral mass screw (LMS). | 1 | 93 | 90 | We prompted to tackle the issue by combining the pedicle screw with the additional use of LMS in attempt to strengthen the fixation. | lateral mass screw | 115 |
synonyms | 0 | xenon | XE demonstrates clinically equivalent bonding performance to CS. | 0 | 27 | 22 | Patients treated with xenon had lower OI levels compared to the control group before surgery (P = 0.002); however, there was no difference in postoperative values between the 2 groups. | XE | 2 |
synonyms | 28 | GC | The degradation kinetics of DBP under different concentrations by the strain QH-12 fit well with the modified Gompertz model (R² > 0.98). | 0 | 34 | 32 | Early diagnosis and tracking of GC is a challenge due to a lack of reliable tools. | DBP | 31 |
synonyms | 112 | Dengue fever | In this article, a strategy is reported that allowed us to identify influential residues on the function of the Dengue NS2b-NS3 Protease. | 0 | 12 | 0 | Dengue fever is an endemic disease in Saudi Arabia, particularly in its Western region. | Dengue | 118 |
label_similarity | 19 | Pelizaeus-Merzbacher disease | We describe here a Pelizaeus-Merzbacher pedigree of the classical type, with X-linked inheritance, a typical clinical progression, and a pathologic loss of myelinating cells and myelin in the central nervous system. | 1 | 130 | 102 | Nonsense mutation in exon 3 of the proteolipid protein gene (PLP) in a family with an unusual form of Pelizaeus-Merzbacher disease. | Pelizaeus-Merzbacher | 39 |
abbreviations | 17 | Chronic Lymphocytic Leukemia | Signals from the CLL microenvironment promote progression of the disease and induce drug resistance. | 1 | 28 | 0 | Chronic Lymphocytic Leukemia (CLL) is a lymphoproliferative disorder with either indolent or aggressive clinical course. | CLL | 20 |
synonyms | 284 | DPYD | Spatial change in the strength and sign of relationships was investigated using geographically weighted regression and significant DPD clusters were identified using the Local Moran's I. Economic factors, like the sharp social gradient between rural and urban areas were important to DPD throughout the west. | 0 | 22 | 18 | Downregulation of DPYD and upregulation of PPAT, UMPS, RRM2, and SLC29A1 transcripts were found in tumors compared to adjacent mucosa in testing and validation sets of patients. | DPD | 287 |
synonyms | 0 | clinical evaluation | Assessment of neuroanatomical and behavioural effects of in ovo methylmercury exposure in zebra finches (Taeniopygia guttata) | 0 | 51 | 32 | They were subjected to detailed clinical evaluation along with hematological, biochemical, microbiological, and electrophysiological studies and followed-up for outcome at 1 and 3 months. | Assessment | 10 |
synonyms | 66 | melanomas | 1-restricted autologous cytolytic T lymphocytes (CTLs) in a human melanoma. | 1 | 73 | 64 | The same mutation was found in one additional melanoma among 28 melanomas analyzed. | melanoma | 74 |
term_identity | 38 | farms | The catchment is in an area of marine farm production and contains freshwater smolt rearing cages. | 0 | 95 | 90 | The short-term effects of farmed fish food consumed by wild fish congregating outside the farms | farm | 42 |
label_similarity | 52 | Group A | MATERIAL AND METHODS Forty rats were divided into 4 groups with 10 rats each. | 0 | 67 | 60 | The rate of failure of ablation at 3 days was 39 (5.6%) for Group A and 3 (0.5%) for Group B (P<0.0001) and at one month it was 46 (10.1%) vs. 27 (6.7%) (P=0.086). | groups | 58 |
synonyms | 81 | long-term potentiation | While stimulating the medial perforant pathway, input-output (I/O) functions and LTP were recorded from the DG to evaluate synaptic potency and plasticity. | 1 | 176 | 154 | At the cellular level, aging is accompanied by a progression of biochemical modifications that ultimately affects its ability to generate and consolidate long-term potentiation. | LTP | 84 |
label_similarity | 13 | CD8(+) T-cell | In contrast, CD8+ cells were significantly decreased (P < 0.05). | 1 | 99 | 86 | Brucella abortus is able to persist inside the host despite the development of potent CD8(+) T-cell responses. | CD8+ cells | 23 |
synonyms | 91 | oral cavity | Recreational use of cannabis, following its legalization in some countries, poses emergent oral and periodontal health concerns. | 0 | 91 | 80 | However, any foreign bodies inserted may provide new niches for the bacteria in oral cavity. | oral | 95 |
label_similarity | 56 | AT | In addition, exendin-4 ameliorated HG - induced p-AKT / AKT lower expression, and this impact was also suppressed by LY294002. | 0 | 44 | 42 | Fine genetic linkage mapping of the mouse AT region was performed using the interspecific backcross mice. | AKT | 59 |
abbreviations | 5 | Scanning electron micrographs | Both SEM and histology confirmed the absence of gaps in the wall of the construct. | 1 | 29 | 0 | Scanning electron micrographs were used to illustrate the detailed structure of the female's genitalia. | SEM | 8 |
synonyms | 103 | molecular markers | HIV-positive dried blood spot samples from Kenya's second AIDS Indicator Survey were tested for an ARV biomarker by liquid chromatography-tandem mass spectrometry. | 1 | 201 | 184 | The increasing number of described Euplotes taxa emphasizes the importance for detailed characterizations of new ones, requiring standardized morphological observations, sequencing of molecular markers and careful comparison with previous literature. | biomarker | 112 |
label_similarity | 177 | uremia | A total of 66 children from 16 Pediatric Oncology Group institutions with "standard-risk" acute lymphoblastic leukemia, 1.00 to 9.99 years at diagnosis, without evidence of CNS leukemia at diagnosis were enrolled on ACCL0131: 28 from P9201 and 38 from P9605. | 0 | 156 | 150 | During the course of nephrotic syndrome, serum urea concentrations increased significantly faster in sgk1(-/-) mice than in sgk1(+/+) mice leading to uremia and a reduced median survival in sgk1(-/-) mice (29 vs. 40 days in sgk1(+/+) mice). | leukemia | 185 |
label_similarity | 87 | cell | Malignancies were found in 4 patients, and all of the malignancies originated from the T-cell / macrophage lineage. | 0 | 164 | 160 | Our findings highlight the key role of surface chemistry in cell - multilayer film interactions, and these engineered nanocoatings represent a tunable model of cell adhesive and non-adhesive multilayered films. | T-cell | 93 |
synonyms | 98 | metabolic | In addition, enhanced LDL - receptor expression increased the transport of LDL-C to the liver for metabolism. | 1 | 89 | 80 | These results have important implications for large-scale SSF, where effects of metabolic heat are detrimental to growth and enzyme production, which are severely affected by the formation of high temperature gradients. | metabolism | 108 |
term_identity | 42 | DON | Few methods exist to track the sources of DON in watersheds. | 0 | 61 | 58 | An example is the thoroughly-investigated deoxynivalenol (DON), which severely impairs gastrointestinal barrier integrity. | DON | 45 |
label_similarity | 14 | TBW | Tuberculosis (TB) is a major health problem in the developing countries. | 0 | 3 | 0 | TBW was used to estimate fat-free mass (FFM), using hydration factors for different ages and gender. | TB | 16 |
label_similarity | 4 | postoperative delirium | The postoperative course was marked by Horner's syndrome that persisted at 1-year follow-up. | 0 | 35 | 13 | Incidence of postoperative delirium is high even in a population without known risk factors. | postoperative course | 24 |
synonyms | 185 | CF | This segmentation method uses artificial neural network module (ANN) in order to classify small overlapping patches as belonging or not-belonging to the region of interest (ROI) of the PF tissue. | 0 | 83 | 81 | Subjects and Methods A total of 201 paired sinus and pulmonary cultures from 105 CF patients were identified between 1996 and 2014. | PF | 187 |
synonyms | 135 | Plasmodium | Using a geoadditive or structured additive semiparametric Poisson regression model, we determined the influence of climatic factors on malaria incidence in four endemic provinces of Zambia. | 0 | 53 | 43 | Malaria is an infectious disease caused by Plasmodium parasites and is transmitted among humans by female Anopheles mosquitoes. | malaria | 142 |
label_similarity | 31 | adenovirus disease | The choice of the name of this eponymous disease had been made by Dr Parkes Weber, an eminent London physician in the 1930s, who had a penchant for eponymous diseases, having had no less than seven attributed to himself, at least in part. | 0 | 106 | 88 | There are no approved antiviral agents with proven efficacy for the treatment of severe adenovirus disease, nor are there any prospective randomized, controlled trials of potentially useful anti-adenovirus therapies. | eponymous disease | 48 |
abbreviations | 17 | CR | After two failed closed reduction attempts, open reduction and C1-C2 fusion were performed with atlas laminar hook and axis pedicle polyaxial screws. | 0 | 29 | 27 | CNS+ patients who achieved CR showed OS comparable to that of CNS- patients. | closed reduction | 33 |
synonyms | 200 | New Zealand white rabbits | We cannot rule out bias due to the non-random sampling of dogs and cats, but the apparent colonisation prevalence of 0% was consistent with the low prevalence of subclinical colonisation in humans in New Zealand. | 0 | 32 | 7 | Thirty New Zealand white rabbits were divided into two groups, B1 and B2 which represent early [fed 1% high cholesterol diet (HCD) for 2 weeks] and established (fed 1% HCD for 8 weeks) atherosclerosis. | New Zealand | 211 |
synonyms | 34 | localized | On examination 64, 74, and 72 had localised hypomineralized enamel defect. | 1 | 26 | 17 | Purpose Men with localized prostate cancer often are treated with external radiotherapy (RT) over 8 to 9 weeks. | localised | 43 |
abbreviations | 32 | CE | They were subjected to detailed clinical evaluation along with hematological, biochemical, microbiological, and electrophysiological studies and followed-up for outcome at 1 and 3 months. | 0 | 7 | 5 | Peak CE levels were associated with a 45% (SD +/- 22%, 95% CI = 22% to 69%) decrease in cardiac output (p < 0.05), a 56% (SD +/- 23%, 95% CI = 32% to 80%) decrease in dP/dt(max) (p <.006), and a 23% (SD +/- 15%, 95% CI = 7% to 49%) decrease in SVO(2) (p < 0.025). | clinical evaluation | 51 |
abbreviations | 131 | randomized controlled trials | We invited 236 adolescents (12-20 years) with juvenile idiopathic arthritis (JIA) to participate in a randomised controlled trial (RCT) transition intervention. | 1 | 34 | 6 | Eight randomized controlled trials (RCTs) that involved 511 patients met the criteria. | RCT | 134 |
synonyms | 87 | progression | To assess the cervical vestibular evoked myogenic potentials (cVEMPs) ability to track disease progression in Ménière's disease patients over time and identify the most sensitive outcome measurement. | 1 | 229 | 218 | Indeed, platelets within atheroma plaques have been shown to play a role in inflammation, in platelet - leucocyte aggregates and in thrombi formation and might thus be considered relevant biomarkers of atherosclerotic progression. | disease progression | 106 |
label_similarity | 30 | Severe-glucose-6-phosphate dehydrogenase (G6PD) deficiency | Molecular characterization of glucose-6-phosphate dehydrogenase (G6PD) deficiency in patients of Chinese descent and identification of new base substitutions in the human G6PD gene. | 1 | 58 | 0 | Severe-glucose-6-phosphate dehydrogenase (G6PD) deficiency associated with chronic hemolytic anemia, granulocyte dysfunction, and increased susceptibility to infections: description of a new molecular variant (G6PD Barcelona). | glucose-6-phosphate dehydrogenase (G6PD) deficiency | 81 |
synonyms | 64 | AE | Withdrawal of Anticancer Therapy in Advanced Disease Because of Side Effects | 0 | 27 | 25 | Autoimmune encephalitis (AE) mediated by antibodies against synaptic and neuronal surface targets frequently presents with a psychiatric syndrome. | Side Effects | 76 |
abbreviations | 86 | Pi | Understanding how PLK1 is activated is therefore crucial for the development of novel PLK1 inhibitors with anticancer properties. | 0 | 141 | 139 | As Pi concentration ([Pi]) was increased from 0 to 30 mmol·L(-1), twitch duration decreased, with progressive reductions in sensitivity to Pi as [Pi] was increased. | PLK1 inhibitors | 101 |
term_identity | 62 | partnerships | This can complicate planning, evaluating, and sustaining such partnerships. | 1 | 37 | 25 | International university partnerships can promote such a perspective through the strengthening of cooperation, exchange, and communication between academic institutions across national boundaries. | partnerships | 74 |
synonyms | 142 | high risk of | Coronectomy procedure is effective in controlling inferior alveolar nerve injury following third molar surgery, in radiographically evaluated high risk cases and it has very low incidence of complications. | 1 | 35 | 23 | Results are limited by high risk of bias. | high risk | 151 |
term_identity | 142 | PTOA | It is increasingly recognized that biochemical abnormalities of the joint precede radiographic abnormalities of posttraumatic osteoarthritis (PTOA) by as much as decades. | 1 | 118 | 114 | A growing body of evidence strongly suggests that the progression from anterior cruciate ligament (ACL) injury to PTOA is multifactorial, involving the interplay between biomechanical disturbances and biochemical homeostasis of articular cartilage. | PTOA | 146 |
label_similarity | 57 | Pendred syndrome | Our results provide evidence of a direct role for WT1 in Denys-Drash syndrome and thus urogenital system development. | 0 | 51 | 35 | Two frequent missense mutations in Pendred syndrome. | Denys-Drash syndrome | 77 |
synonyms | 130 | Cu | One example of this complex situation is the significant economic and environmental costs associated with diluting and processing copper concentrates containing arsenic (in the form of the mineral enargite, Cu3 AsS4) in the production of pure copper. | 1 | 15 | 13 | Accordingly, Cu presence affected the response of the rhizosphere microbial community and in some cases that response was significantly different when Cu was in NP form. | copper | 136 |
term_identity | 21 | AF | Atrial fibrillation (AF) is a common clinically significant cardiac arrhythmia. | 1 | 132 | 130 | Heart specimens from 30 patients died from cardiovascular causes (64 ± 12 years, 17 men) were collected in three equal groups: no AF, paroxysmal AF, and permanent AF. | AF | 23 |
abbreviations | 171 | RF | The present chapter also discusses ways to directly influence social approach and avoidance behavior and will end with a research agenda to further advance this important research field. | 0 | 78 | 76 | The highest rate of recurrence of TN was encountered in patients undergoing RF (64%). | research field | 185 |
synonyms | 115 | anxiety symptom | Participants attending reminiscence sessions exhibited better outcomes compared to the control group in cognition, anxiety and depression (p<0.001), and presented a higher number of retrieved autobiographical events, specificity of evoked memories and positive valence of events (p<0.001), and also presented lower latency time for recalling events, and lower negative recalled events (p<0.01). | 0 | 60 | 45 | The vmPFC hypoactivation was associated with anxiety symptom severity (r = -0.420, P = .01 for conditioning and r = -0.464, P = .004 for extinction recall) and the number of co-occuring anxiety disorders diagnosed (ηp2 = 0.137, P = .009 for conditioning and ηp2 = 0.227, P = .004 for extinction recall). | anxiety | 122 |
term_identity | 28 | decisions | And who should make the RTP decision? | 1 | 166 | 157 | Despite most parents seeking information on the Internet, trust in and advice from health care professionals appeared to be key factors influencing parental decisions. | decision | 36 |
synonyms | 62 | HRT | This drug was developed for treatment of antibody deficiency (replacement therapy), although its use has expanded into many anti-inflammatory and immunomodulatory applications in recent years. | 0 | 148 | 145 | The Massachusetts General Hospital-Hair Pulling Scale Total Score decreased from 15.14 ± 3.86 at baseline to 7.14 ± 5.54 at posttreatment in the HRT group (t20 = 6.16, p < 0.001, d = 1.34); the TAU group changed from 14.16 ± 4.51 to 12.26 ± 4.34 (t18 = 1.50, p = 0.15, d = 0.34). | replacement therapy | 81 |
label_similarity | 70 | chest | Systemic alitretinoin has been shown to be effective in patients with CHE who are refractory to topical corticosteroids. | 0 | 16 | 11 | For males, chest TDC values differed among races (P<.01) mainly due to large African-American TDC values. | CHE | 73 |
term_identity | 0 | Epilepsy | Epilepsy in ring chromosome 20 syndrome | 1 | 8 | 0 | Epilepsy exhibited an age dependent course. | Epilepsy | 8 |
abbreviations | 38 | RA | Here we review the factors related to risk assessment regarding viral vector usage in animals and the relevant regulatory documents associated with this research, and we highlight the most commonly used viral vectors in research today. | 0 | 86 | 84 | PATIENTS AND METHODS: A total of 4086 patients (mean age 60.8 years) diagnosed with RA were enrolled and received etoricoxib 90 mg daily (n = 2032) or diclofenac 75 mg twice daily (n = 2054). | risk assessment | 53 |
synonyms | 82 | blood coagulation | For this reason, individualized therapeutic approaches in patients suffering from coagulation - associated organ dysfunction might be feasible. | 0 | 43 | 26 | Progestational agents and blood coagulation. | coagulation | 93 |
label_similarity | 68 | type 2 diabetic | AT inflammation is a key factor causing insulin resistance and thus type 2 diabetes, both linked to atherosclerotic cardiovascular disease. | 1 | 27 | 12 | METHODS: In type 2 diabetic patients, cases who developed CAD were compared retrospectively with controls that did not. | type 2 diabetes | 83 |
label_similarity | 32 | Type II complement protein C2 deficiency | These data demonstrate that 1) type I human complement C2 deficiency is caused by a 28-base pair genomic deletion that causes skipping of exon 6 during RNA splicing, resulting in generation of a premature termination codon, | 1 | 40 | 0 | Type II complement protein C2 deficiency is characterized by a selective block in C2 secretion. | type I human complement C2 deficiency | 69 |
abbreviations | 58 | pelvic inflammatory disease | Chlamydia infection in acute pelvic inflammatory disease (PID) is associated with serious complications including ectopic pregnancy, tubal infertility, Fitz-Hugh-Curtis syndrome and tubo-ovarian abscess (TOA). | 1 | 96 | 69 | Although the course of infection is often asymptomatic, CT may cause pelvic inflammatory disease (PID), leading to severe complications, such as prolonged time to pregnancy, ectopic pregnancy, and tubal factor subfertility. | PID | 61 |
label_similarity | 32 | breast/ovarian cancer | OBJECTIVE To determine whether hereditary ovarian cancers have distinct clinical and pathological features compared with sporadic (nonhereditary) ovarian cancers. | 1 | 61 | 40 | In this study we investigated 45 German breast/ovarian cancer families for germline mutations in the BRCA1 gene. | hereditary ovarian cancers | 58 |
label_similarity | 168 | neurological dysfunctions | NMDA receptor signaling is critical for the development of synaptic plasticity, learning, and memory, and dysregulation of NMDAR signaling is implicated in a number of neurological disorders including schizophrenia (SZ). | 1 | 95 | 70 | After dexamethasone treatment, children showed a higher rate of minor neurological dysfunctions. | neurological disorders | 190 |
term_identity | 18 | hypokalemia | The more profound hypokalemia, the greater the propensity for the occurrence of PVC's. | 1 | 50 | 39 | Amelioration of bendrofluazide-induced hypokalemia by timolol. | hypokalemia | 29 |
abbreviations | 98 | SN | Although sorting nexin (SNX) family proteins regulate this trafficking, the relevance and role of sorting nexin-4 (SNX4) regarding AD has not been studied yet. | 0 | 188 | 186 | The aim of this study is to investigate the effects of L-type calcium channels (LTCCs) on MPTP - induced dopamine (DA) neuron degeneration and iron accumulation in the substantia nigra (SN) of mice. | sorting nexin-4 | 113 |
synonyms | 57 | infectious diseases | We investigated the mechanisms of neuropathogenesis DENV infection in rhesus macaques. | 0 | 208 | 189 | Only recently, Tsps have started to acquire relevance as potential new drug targets as they contribute, via protein-protein interactions, to numerous pathophysiological processes including infectious diseases and cancer. | infection | 66 |
abbreviations | 44 | Mesenchymal stem cells | The results indicate that CCR2 expressed on MSC - exo may play a key role in inflammation regulation and renal injury repair by acting as a decoy to suppress CCL2 activity. | 1 | 22 | 0 | Mesenchymal stem cells (MSC) have been reported to reduce hepatic IRI because of their reparative immunomodulatory effects in injured tissues. | MSC | 47 |
synonyms | 46 | Dengue fever | Association of interleukin-2, -4 and -10 with dengue severity | 1 | 12 | 0 | Dengue fever is an endemic disease in Saudi Arabia, particularly in its Western region. | dengue | 52 |
label_similarity | 87 | ND | Here we report the isolation and analysis of human genomic DNA clones encompassing the NDP gene. | 1 | 66 | 64 | The mutation of the initiation codon would cause the failure of ND gene expression or a defect in translation thereby truncating the amino terminus of ND protein. | NDP | 90 |
label_similarity | 155 | mRCC | The purpose of our study was to demonstrate the imaging features of various anatomical variants of IHD using magnetic resonance cholangio-pancreatography (MRCP) and their prevalence in our population. | 0 | 91 | 87 | Bone metastases (BMs) occur commonly in patients with metastatic renal cell carcinoma (mRCC). | MRCP | 159 |
synonyms | 59 | mercury | We hypothesized then, that different NOXs may have role in HG - induced neural cell injury. | 0 | 106 | 99 | The Langmuir model was adequately fitted to the adsorption isotherm, thereby obtaining the maximum mercury adsorption capacity of 111.1 ± 0.3 mg g(-1). | HG | 61 |
synonyms | 179 | document | Our findings indicate that connectivity decreases associated with propofol sedation, involving the thalamus and insula, are relatively small compared with those already caused by DOC -associated structural brain injury. | 0 | 104 | 96 | Pre-hospital policies for the care of patients with acute coronary syndromes in India: A policy document analysis | DOC | 182 |
term_identity | 16 | analogue | Here, benzamide analogues based on previous HTS hits have been purchased or synthesized. | 0 | 88 | 80 | Evaluation methods included vertical relative probing attachment level (RAL-V), analogue and digital intra-oral radiography and bone sounding without and with flap elevation. | analogues | 25 |
synonyms | 25 | blood transfusion | Perioperative anemia and blood product transfusion increases short-term and long-term morbidity and mortality during cardiac surgery. | 1 | 89 | 72 | Preterm infants of gestational age ≤ 32 weeks are likely candidates for blood transfusion during treatment. | blood product transfusion | 50 |
label_similarity | 43 | TGF-β | Our findings provide proof-of-concept that TGFβ contributes to the anti-inflammatory effect of TUDCA under neuroinflammatory conditions. | 1 | 35 | 30 | Transforming Growth Factor β (TGF-β) is a multifunctional cytokine that plays a role in several biological processes. | TGFβ | 47 |
term_identity | 4 | cell proliferation | The cell proliferation, cell cycle and Transwell invasion assays were performed. | 0 | 43 | 25 | Quantitative analysis of cell proliferation by a dye dilution assay: Application to cell lines and cocultures | cell proliferation | 22 |
label_similarity | 101 | VUE images | The framework is applicable for gold standard setup on any rigid anatomy, provided that the acquired images contain spatially grouped fiducial markers. | 1 | 10 | 0 | VUE images were processed off of arterial (VUE-art) and venous (VUE-ven) phase series. | images | 107 |
label_similarity | 63 | type 2 diabetic | KMAP-O framework for care management research of patients with type 2 diabetes | 1 | 27 | 12 | METHODS: In type 2 diabetic patients, cases who developed CAD were compared retrospectively with controls that did not. | type 2 diabetes | 78 |
label_similarity | 0 | Escherichia coli | Escherichia coli HGT: Engineered for high glucose throughput even under slowly growing or resting conditions | 1 | 73 | 57 | Here, we demonstrate that MVT can detect inactivation of Escherichia coli, Aeromonas hydrophila, and Enterococcus faecalis cells by ultraviolet (UV) irradiation. | Escherichia coli HGT | 20 |
abbreviations | 55 | NDV | Mesenchymal stem cells enhance the oncolytic effect of Newcastle disease virus in glioma cells and glioma stem cells via the secretion of TRAIL | 1 | 126 | 123 | These results suggest that factor(s) secreted by the infected MSCs sensitized the glioma cells to the cytotoxic effects of NDV. | Newcastle disease virus | 78 |
synonyms | 82 | cognitive function | In addition, correlations between objectively measured and subjectively evaluated cognitive functioning were estimated. | 1 | 55 | 37 | The clinico- radiological paradox of cognitive function and MRI burden of white matter lesions in people with multiple sclerosis: A systematic review and meta-analysis | cognitive functioning | 103 |
abbreviations | 54 | insulin resistance | Possibly this combined with impaired fasting glucose, IR and dyslipidemia, could account for Cardio vascular risks in PCOS. | 1 | 67 | 49 | Reduced circulatory APN level is associated with insulin resistance and T2DM. | IR | 56 |
label_similarity | 149 | seasonal allergic rhinitis | Multicenter, double-blind, multiple-dose, parallel-groups efficacy and safety trial of azelastine, chlorpheniramine, and placebo in the treatment of spring allergic rhinitis. | 1 | 86 | 60 | Azelastine appears to be a safe, efficacious medication for seasonal allergic rhinitis. | spring allergic rhinitis | 173 |
synonyms | 62 | HLH | Extracorporeal membrane oxygenation outcomes in children with hemophagocytic lymphohistiocytosis | 1 | 154 | 151 | Compared with all pediatric patients in the ELSO registry during the study period (n=17,007), HLH patients had worse hospital survival (non-HLH 59% vs HLH 30%, p =0.001). | hemophagocytic lymphohistiocytosis | 96 |
synonyms | 48 | Leucocytoclastic vasculitis | Leukocytoclastic vasculitis (LV) is primarily a cutaneous small vessel vasculitis, though systemic involvement may be encountered. | 0 | 27 | 0 | Leucocytoclastic vasculitis presents as palpable purpura of the lower extremities often accompanied by abdominal pain, arthralgia, and renal involvement. | cutaneous small vessel vasculitis | 81 |
abbreviations | 22 | FNDI | Molecular analysis in familial neurohypophyseal diabetes insipidus: early diagnosis of an asymptomatic carrier. | 1 | 50 | 46 | Familial neurohypophyseal diabetes insipidus (FNDI) is an inherited deficiency of the hormone arginine vasopressin (AVP) and is transmitted as an autosomal dominant trait. | familial neurohypophyseal diabetes insipidus | 66 |