text stringlengths 0 197k |
|---|
Moreover, the two groups will be compared regarding mortality and morbidity (secondary end-point). |
The second arm of the study will consider the population undergoing surgery, develop a model able to predict the length of hospitalization, and compare the open vs laparoscopic approach (primary end-point), and mortality, morbidity, and surgical outcome indices (secondary end-point). conditions: Acute Diverticulitis st... |
<|newrecord|> nctId: NCT06388525 id: PostERCPLC briefTitle: Post-ERCP Cholecystectomy. How ERCP and ERCP-related Variables Effect the Outcomes? overallStatus: COMPLETED date: 2016-01-01 date: 2020-01-01 date: 2020-01-01 date: 2024-04-29 date: 2024-04-29 name: Kanuni Sultan Suleyman Training and Research Hospital class:... |
<|newrecord|> nctId: NCT06388512 id: STUDY00160044 briefTitle: iMRI Prone Positioning Frame Design Feasibility Study overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2024-12 date: 2024-12 date: 2024-04-29 date: 2024-04-29 name: University of Kansas Medical Center class: OTHER name: Continuum Educational Technologi... |
* Is the prototype prone positioning device design feasible for use during neurosurgical procedures which utilize intraoperative MRI? |
* Does use of the prototype device place the patient at increased risk of complications compared to the standard positioning pads? Researchers will place patients in the prone position on the prototype device during neurosurgical procedures that utilize intraoperative MRI and observe for any problems with the positioni... |
<|newrecord|> nctId: NCT06388499 id: GOIPG/2022/1854 briefTitle: A Physiotherapy-led Disease-agnostic Telerehabilitation Programme for People With Chronic Health Conditions overallStatus: RECRUITING date: 2024-04-16 date: 2024-07-22 date: 2024-07-31 date: 2024-04-29 date: 2024-04-29 name: University of Limerick class: ... |
<|newrecord|> nctId: NCT06388486 id: UMCGoettingen9/9/16 briefTitle: Cytokine-Induced Transcription in Depressed Inpatients Undergoing Psychotherapy acronym: CitDip overallStatus: COMPLETED date: 2017-01-01 date: 2022-03-09 date: 2024-01-01 date: 2024-04-29 date: 2024-04-29 name: University Medical Center Goettingen cl... |
* Do psychological traits (i.e.: social inhibition, negative affectivity, ...) affect the activation of immunomodulatory transcription factors (STAT3, NFkB) in depressed patients? |
* Are subjects with these psychological traits affected differently by psychotherapeutic intervention? |
Study subjects are assessed for their psychological and behavioral traits and receive psychotherapeutic care over several weeks during hospital treatment. Peripheral blood mononuclear cells are isolated from the study subjects, and activation of transcription factors is measured by flow cytometry. conditions: Depressio... |
<|newrecord|> nctId: NCT06388473 id: NMRR-20-2188-56086 IIR briefTitle: Implementation of a Web-based App for Screening in Men in a Malaysian Primary Care Setting acronym: iScreenMen overallStatus: COMPLETED date: 2021-01-14 date: 2021-06-06 date: 2021-06-06 date: 2024-04-29 date: 2024-04-29 name: University of Malaya ... |
<|newrecord|> nctId: NCT06388460 id: STUDY00001015 id: R01HL169229 type: NIH link: https://reporter.nih.gov/quickSearch/R01HL169229 briefTitle: Asthma Link Effectiveness Trial: Cluster Randomized Controlled Trial overallStatus: RECRUITING date: 2024-04-04 date: 2028-01 date: 2028-04 date: 2024-04-29 date: 2024-04-29 na... |
<|newrecord|> nctId: NCT06388447 id: UCMSC1 briefTitle: Reconstruction of Deficient Interdental Papilla Using Stem Cells vs Physiological Saline: a RCT overallStatus: ENROLLING_BY_INVITATION date: 2023-12-01 date: 2024-12-31 date: 2025-03-30 date: 2024-04-29 date: 2024-04-29 name: University of Malaya class: OTHER brie... |
<|newrecord|> nctId: NCT06388434 id: HP-00100309 briefTitle: Protective Arm Balance Responses acronym: PAT overallStatus: RECRUITING date: 2023-10-01 date: 2024-07 date: 2024-08 date: 2024-04-29 date: 2024-04-29 name: University of Maryland, Baltimore class: OTHER briefSummary: The overall objective of this study is to... |
Participants will be involved in 6 sessions. Session 1 will include the assessment, questionnaires, and training. Session 2 will include just the training. Session 3 will include the assessment and training. Sessions 4-5 will include just the training. Session 6 will include the assessment, questionnaires, and training... |
<|newrecord|> nctId: NCT06388421 id: GMS-PH-401 briefTitle: DeciPHer-ILD: A Real-world Patient Registry in Group 3 Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD) overallStatus: NOT_YET_RECRUITING date: 2024-08-01 date: 2030-08-01 date: 2030-11-30 date: 2024-04-29 date: 2024-04-29 name: United... |
<|newrecord|> nctId: NCT06388408 id: SufMAST briefTitle: Effects of Sufentanil Target Controlled Infusion on Patient State Index Values and Electroencephalographic Spectrum During Total Intravenous Anesthesia With Propofol overallStatus: NOT_YET_RECRUITING date: 2024-05-05 date: 2024-09-15 date: 2024-09-30 date: 2024-0... |
Authors aim to investigate its effect on Patient State index (PSi), the power spectrum EEG, the Analgesia Nociception Index (ANI) nad pupillometry values during maintenance durin TIVA-TCI with Propofol and Sufentanil. conditions: Anesthesia Brain Monitor conditions: Sufentanil conditions: Target Controlled Infusion stu... |
<|newrecord|> nctId: NCT06388395 id: REC-23-05-12-02-F briefTitle: Clinical Performance of All-on-4 PEEK and Conventional Prostheses overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2027-06-30 date: 2027-08-30 date: 2024-04-29 date: 2024-04-29 name: University of Sharjah class: OTHER briefSummary: The all-on-4 ... |
<|newrecord|> nctId: NCT06388382 id: UKKx2024 briefTitle: Investigation of the Audible ICD Alert Tone overallStatus: NOT_YET_RECRUITING date: 2024-05-15 date: 2025-05-15 date: 2025-05-30 date: 2024-04-29 date: 2024-04-29 name: Universitätsklinikum Köln class: OTHER briefSummary: Ability of ICD patients to hear the audi... |
<|newrecord|> nctId: NCT06388369 id: CA184-608 briefTitle: Neoadjuvant Lu-PSMA Radioligand Therapy and Ipilimumab in Men With Very High-risk Prostate Cancer acronym: NEPI overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2027-03 date: 2028-09 date: 2024-04-29 date: 2024-04-29 name: University Hospital, Essen class:... |
If it is established that Ipilimumab (3mg/kg) + \[177Lu\]Lu-PSMA-617 RLT (7,4 GBq) is appropriately tolerated, patients will be randomized into the two arms of the Analysis Cohort: |
* Arm A: Ipilimumab + \[177Lu\]Lu-PSMA-617 RLT |
* Arm B: \[177Lu\]Lu-PSMA-617 RLT primaryPurpose: TREATMENT masking: NONE count: 58 type: ESTIMATED name: [177Lu]Lu-PSMA-617 name: Ipilimumab measure: Feasibility to perform prostatectomy on time measure: Clinical activity: Proportion of participants in the full analysis set who achieve a pCR measure: Safety Profile of... |
<|newrecord|> nctId: NCT06388356 id: 042024 briefTitle: Patient's Informational Privacy in Prehospital Emergency Care - Educational Intervention Study for the Paramedics overallStatus: ENROLLING_BY_INVITATION date: 2024-03-25 date: 2024-05-19 date: 2024-06-16 date: 2024-04-29 date: 2024-04-29 name: Eini Koskimies class... |
The main questions it aims to answer are: |
1. What is the effect of the educational intervention on the |
1. theoretical knowledge of paramedics' regarding IP? |
2. the paramedics' attitude towards patient's IP? |
2. What is the usability and feasibility of the intervention being evaluated according to the respondents? conditions: Knowledge conditions: Attitude of Health Personnel studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Two groups, intervention and con... |
<|newrecord|> nctId: NCT06388343 id: S68485 briefTitle: Causes of Listening Difficulties in Children acronym: CLINIC overallStatus: NOT_YET_RECRUITING date: 2025-01 date: 2027-12 date: 2027-12 date: 2024-04-29 date: 2024-04-29 name: Universitaire Ziekenhuizen KU Leuven class: OTHER name: Universitair Ziekenhuis Brussel... |
CLINIC aims to develop a new approach to diagnose the causes of listening difficulties in children. This is accomplished through (1) a validated parent questionnaire and (2) a multidisciplinary behavioral assessment tool. Data from these combined measures will lead to evidence-based profiles of children with LiD, which... |
<|newrecord|> nctId: NCT06388330 id: s61692 briefTitle: The Effect of a Low FODMAP Diet in Functional Dyspepsia Patients With Meal Related Symptoms acronym: FFD overallStatus: COMPLETED date: 2019-04-26 date: 2022-03-08 date: 2022-03-08 date: 2024-04-29 date: 2024-04-29 name: Universitaire Ziekenhuizen KU Leuven class:... |
<|newrecord|> nctId: NCT06388317 id: 123632 briefTitle: Machine-based Algorithm for Increased Physical Activity and Sustained User Engagement overallStatus: ACTIVE_NOT_RECRUITING date: 2023-01-01 date: 2025-01-01 date: 2025-02-01 date: 2024-04-29 date: 2024-04-29 name: Western University, Canada class: OTHER briefSumma... |
<|newrecord|> nctId: NCT06388304 id: 23-0556 briefTitle: THRIVE Study: Positive Affect Training for Endocrine Therapy Medication Adherence acronym: THRIVE overallStatus: RECRUITING date: 2024-03-12 date: 2024-10-12 date: 2024-12-12 date: 2024-04-29 date: 2024-04-29 name: Joanna Arch class: OTHER briefSummary: The purpo... |
<|newrecord|> nctId: NCT06388291 id: CTU/2018/321 briefTitle: Deep Brain Stimulation in Tourette Syndrome acronym: Op-TICS overallStatus: RECRUITING date: 2022-08-02 date: 2025-01 date: 2025-06-30 date: 2024-04-29 date: 2024-04-29 name: University College, London class: OTHER name: National Institute for Health Researc... |
It is a randomised, double-blind, crossover clinical investigation for 20 patients. Op-TICS will be performed at the National Hospital for Neurology \& Neurosurgery. |
Following DBS surgery, participants will first enter an open adjustment phase, of 6 months, where the electrical stimulation settings of the device are optimised. Participants will then enter the double-blind phase that will include successively up to 2 weeks with stimulation on and up to 2 weeks with the stimulation o... |
The primary outcome measure is the tic severity score measured by the Yale Global Tic Severity Scale -Total Tic Score after two weeks OFF-stimulation versus two weeks ON-stimulation in the double-blind randomised crossover phase conditions: Tourette Syndrome conditions: Deep Brain Stimulation studyType: INTERVENTIONAL ... |
This will be followed by a 6 months open-phase period of stimulation for electrical parameter adjustment. |
Following these 6 months, participants will be randomised into two groups by the order of treatment condition (ON/OFF-stimulation vs OFF/ON-stimulation): one group will be kept with the stimulation on ("ON-stimulation") and the other switched off ("OFF-stimulation") for up to two weeks. Tic severity will be assessed an... |
<|newrecord|> nctId: NCT06388278 id: NET-2018-12366982-4/ASP_LOMB briefTitle: Cost-effectiveness Analysis of an Antimicrobial Stewardship Program in Regione Lombardia (RF-net2018) acronym: RF-net2018 overallStatus: RECRUITING date: 2023-03-01 date: 2024-11-01 date: 2025-04-15 date: 2024-04-29 date: 2024-04-29 name: Fon... |
<|newrecord|> nctId: NCT06388265 id: 18/2018, Acta 26-6-2018 briefTitle: Emotional and Oral Characteristics of Patients That Attend a Dental Consultation for the Extraction of Third Molars overallStatus: COMPLETED date: 2022-01-09 date: 2023-07-31 date: 2023-07-31 date: 2024-04-29 date: 2024-04-29 name: University of B... |
<|newrecord|> nctId: NCT06388252 id: ERID-KSOPR-0049/2023 id: 0120-297/2023/3 type: OTHER domain: National Medical Ethics Committee of the Republic of Slovenia briefTitle: Electrochemotherapy Induces Changes in the Tumor Microenvironment of Cutaneous and Subcutaneous Metastases in Patients With Cutaneous Melanoma overa... |
Studies have shown that with some interventions we can change the tumor microenvironment from being immune-cold to being immune-hot. Electrochemotherapy is one of the interventions that might improve the efficacy of immunotherapy in cutaneous melanoma. Electrochemotherapy is an established method for the local treatmen... |
The primary objective is to evaluate the changes in the tumor microenvironment of cutaneous and subcutaneous melanoma metastases induced by electrochemotherapy, based on the histologic analysis of treated and untreated metastases before and after treatment. The secondary aim is to determine whether the changes in the t... |
The results will help us to better understand the synergistic effects of electrochemotherapy and immunotherapy on cutaneous melanoma metastases. The combination of systemic immunotherapy and electrochemotherapy could become an important treatment method for patients with metastatic melanoma. conditions: Cutaneous Malig... |
<|newrecord|> nctId: NCT06388239 id: BE24-006 briefTitle: Bioequivalence Study of Apixaban 5 mg Film-coated Tablets in Healthy Thai Volunteers overallStatus: NOT_YET_RECRUITING date: 2024-08-26 date: 2024-09-14 date: 2024-09-23 date: 2024-04-29 date: 2024-04-29 name: International Bio service class: NETWORK briefSummar... |
<|newrecord|> nctId: NCT06388226 id: IRB # 16143 briefTitle: Leg Heat Therapy in Heart Failure With Preserved Ejection Fraction overallStatus: NOT_YET_RECRUITING date: 2024-05-06 date: 2026-07-31 date: 2026-07-31 date: 2024-04-29 date: 2024-04-29 name: Indiana University class: OTHER name: Purdue University briefSummar... |
<|newrecord|> nctId: NCT06388213 id: GLP-1 RA patients GE by GUS briefTitle: Investigation of the Evolution of Gastric Emptying by Gastric Ultra Sonography in Patients Treated With GLP-1 Receptor Agonists on a 7 Days Pausing Period. overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2025-06 date: 2026-05 date: 2024-... |
<|newrecord|> nctId: NCT06388200 id: OCU400-301 briefTitle: A Phase 3 Study Of OCU400 Gene Therapy for the Treatment Of Retinitis Pigmentosa acronym: liMeliGhT overallStatus: RECRUITING date: 2024-04-26 date: 2025-06-30 date: 2026-10-30 date: 2024-04-29 date: 2024-04-29 name: Ocugen class: INDUSTRY briefSummary: This i... |
This is a multicenter, assessor blinded and randomized study which will enroll 150 subjects. conditions: Retinitis Pigmentosa studyType: INTERVENTIONAL phases: PHASE3 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE maskingDescription: This is outcome assessor blinded study w... |
<|newrecord|> nctId: NCT06388187 id: NN9838-7749 id: U1111-1298-3451 type: OTHER domain: World Health Organization (WHO) id: 2023-509273-24 type: OTHER domain: European Medical Agency (EMA) briefTitle: A Research Study to See How Well Different Doses of CagriSema Help People With Excess Body Weight Lose Weight overallS... |
<|newrecord|> nctId: NCT06388174 id: S2022-0336 briefTitle: Idiopathic Generalized Epilepsy Syndromes overallStatus: RECRUITING date: 2023-01-01 date: 2026-12-31 date: 2033-12-31 date: 2024-04-29 date: 2024-04-29 name: Second Affiliated Hospital, School of Medicine, Zhejiang University class: OTHER briefSummary: The id... |
According to the new ILAE definition in 2022, the study aims to describe the clinical features, electroencephalographic, imaging findings and long-term prognosis. conditions: Epilepsy conditions: Epilepsy, Idiopathic Generalized studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 200... |
<|newrecord|> nctId: NCT06388161 id: Yan2022-0336 briefTitle: Neural Autoantibody Prevalence in New-onset Focal Seizures of Unknown Etiology overallStatus: RECRUITING date: 2023-08-01 date: 2025-12-31 date: 2030-12-31 date: 2024-04-29 date: 2024-04-29 name: Second Affiliated Hospital, School of Medicine, Zhejiang Unive... |
It is essential to recognize these patients early and to perform antibody testing, as studies have reported early immunotherapy can improve their clinical outcomes. At the same time, it is important to limit the number of patients who require testing, for the sake of specificity and cost effectiveness. Thus, this prosp... |
<|newrecord|> nctId: NCT06388148 id: XL STROKE-2 briefTitle: Endovascular Treatment for eXtra-Large Ischemic Stroke acronym: XL STROKE-2 overallStatus: NOT_YET_RECRUITING date: 2024-07-01 date: 2026-10-31 date: 2027-01-31 date: 2024-04-29 date: 2024-04-29 name: Zhongming Qiu class: OTHER name: The First Affiliated Hosp... |
<|newrecord|> nctId: NCT06388135 id: SNC-01 briefTitle: Serplulimab Combined With Nab-paclitaxel and Cisplatin in Neoadjuvant Therapy for Resectable Esophageal Squamous Cell Carcinoma overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2026-05 date: 2027-05 date: 2024-04-29 date: 2024-04-29 name: Yang Jianjun, PhD... |
The efficacy and safety of combining the programmed death 1 (PD-1) inhibitor serplulimab with nab-paclitaxel and cisplatin as neoadjuvant therapy in patients with resectable ESCC will be evaluated. Methods and analysis: A prospective, single-center, open-label cohort study will enroll 80 patients, with 40 patients allo... |
Ethics: Ethics approval has been obtained from the Ethics Committee at the First Affiliated Hospital (Xijing Hospital) of Air force Military Medical University (KY20242052-C-1). conditions: Esophageal Squamous Cell Carcinoma studyType: INTERVENTIONAL phases: PHASE4 allocation: NON_RANDOMIZED interventionModel: PARALLEL... |
<|newrecord|> nctId: NCT06388122 id: 23-009689 id: NCI-2024-03405 type: REGISTRY domain: CTRP (Clinical Trials Reporting Program) id: MC240301 type: OTHER domain: Mayo Clinic briefTitle: DiviTum®TKa: A Biomarker Assay for Efficacy in HR+ Metastatic Breast Cancer Patients overallStatus: NOT_YET_RECRUITING date: 2024-06-... |
<|newrecord|> nctId: NCT06388109 id: IRB15-00741 briefTitle: Positive Peers Intervention Clinical Trial acronym: PoPIT overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2027-05 date: 2027-11 date: 2024-04-29 date: 2024-04-29 name: MetroHealth Medical Center class: OTHER name: Kent State University briefSummary: The... |
Does use of the Positive Peers app improve viral suppression among young minority persons with HIV? What user characteristics are associated with a) viral suppression, b) retention in care, and c) perceived HIV-related stigma? |
Participants will: |
* download the mobile app onto their personal smartphone |
* Use the mobile app as they find useful |
* complete online surveys at enrollment, 3 mo, 6, mo, 9 mo and 12 months. conditions: HIV Infections studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: randomized control trial with observational cohort for eligible patients who decline participation pr... |
<|newrecord|> nctId: NCT06388096 id: PERGCLAD001 briefTitle: CLAD Deconvolved PERG Responses in Glaucoma Patients overallStatus: RECRUITING date: 2023-06-01 date: 2025-06-01 date: 2025-06-01 date: 2024-04-29 date: 2024-04-29 name: Jorvec Corp. class: INDUSTRY name: University of Miami briefSummary: Glaucoma is a progre... |
<|newrecord|> nctId: NCT06388083 id: LBS-008-CT07 briefTitle: A Phase 2/3 Study to Evaluate the Efficacy and Safety of Tinlarebant in Subjects With Stargardt Disease acronym: DRAGON II overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2027-06 date: 2027-07 date: 2024-04-29 date: 2024-04-29 name: Belite Bio, Inc cla... |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.