text stringlengths 0 197k |
|---|
<|newrecord|> nctId: NCT06389448 id: pCLE vs EB 2024tj briefTitle: Comparison of pCLE and EB in Gastric Lesion Diagnosis overallStatus: RECRUITING date: 2024-04-11 date: 2026-04 date: 2026-10 date: 2024-04-29 date: 2024-04-29 name: Huazhong University of Science and Technology class: OTHER briefSummary: This is a prosp... |
<|newrecord|> nctId: NCT06389435 id: 2024DS id: Knee type: OTHER domain: Danderyds sjukhus briefTitle: RObotic-assisted Versus Conventional Knee Endoprosthetic Techniques acronym: ROCKETS overallStatus: RECRUITING date: 2024-03-04 date: 2027-01 date: 2028-01 date: 2024-04-29 date: 2024-04-29 name: Danderyd Hospital cla... |
The study aims to systematically evaluate the clinical and economic impacts of Robotic-Assisted Total Knee Replacement (RTKR) compared to conventional Total Knee Replacement (TKR). It focuses on the potential benefits of RTKR, including improved precision in surgery, potentially leading to better patient outcomes and r... |
Study design: |
Multicentre,, preference-tolerant, randomized, controlled, superiority trial with two treatment arms that compares the outcomes of RTKR with traditional TKR techniques. |
Study population: |
Adult patients aged 18 years and older who are eligible for TKR as per local guidelines and who have given informed consent to participate in the study. |
Number of patients: |
400 |
Inclusion criteria: |
Patients must be adults aged 18 years and older, eligible for TKR according to local guidelines, and willing to participate in the study. |
Exclusion criteria: |
Patients with extreme malalignment requiring special implants or techniques, patients unfit for surgery due to medical reasons, and those deemed unsuitable to participate in the study for other reasons. |
Primary outcome variables: |
The Forgotten Joint Score (FJS) at 2 years after surgery conditions: Knee Arthroplasty, Total conditions: Robotic-assisted conditions: Osteoarthritis of the Knee studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: OUTCOMES_ASSESSOR... |
<|newrecord|> nctId: NCT06389422 id: NCC4620 briefTitle: Phase II Study of Moderate-dose Hypofractionated RT Combined With Pembrolizumab for HCC With Diffuse Tumor Thrombosis overallStatus: RECRUITING date: 2024-05-01 date: 2026-04-30 date: 2027-04-30 date: 2024-04-29 date: 2024-04-29 name: Cancer Institute and Hospita... |
<|newrecord|> nctId: NCT06389409 id: Protocollo N.2009 Testicolo briefTitle: Study on the Quality of Life and Functional/Oncological Outcome of Testicular Cancer Patients overallStatus: RECRUITING date: 2010-08-24 date: 2030-09-01 date: 2040-08-31 date: 2024-04-29 date: 2024-04-29 name: IRCCS San Raffaele class: OTHER ... |
From this perspective, the aim of this project is the improving of scientific knowledge of the disease and develop appropriate and effective procedures for the diagnosis and treatment of the patient. conditions: Testicular Cancer studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 30... |
<|newrecord|> nctId: NCT06389396 id: CP362 briefTitle: Investigation of a New Rectal Catheter for Users of Transanal Irrigation overallStatus: RECRUITING date: 2024-04-08 date: 2024-06-30 date: 2024-06-30 date: 2024-04-29 date: 2024-04-29 name: Coloplast A/S class: INDUSTRY briefSummary: The clinical investigation is a... |
The clinical investigation will be conducted as a multi-centre clinical investigation in two different clinical investigation sites in Denmark. conditions: Bowel Management studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER primaryPurpose: PREVENTION masking: NONE count: 20 type: E... |
<|newrecord|> nctId: NCT06389383 id: 22-0182 briefTitle: Pilot Study - Monitoring the Nasal Microbiome and Viral Respiratory Infections in Newborn Hospitalized in Neonatalogy. acronym: NEONATMICROBIO overallStatus: ACTIVE_NOT_RECRUITING date: 2022-12-21 date: 2023-06-30 date: 2024-12 date: 2024-04-29 date: 2024-04-29 n... |
<|newrecord|> nctId: NCT06389370 id: knowledge, Attitude, Behaviour briefTitle: ASSESSMENT OF ORAL HEALTH KNOWLEDGE, ATTITUDE AND BEHAVIOUR AND ITS ASSOCIATION WITH SOCIODEMOGRAPHIC FACTORS OF PRECLINICAL AND CLINICAL DENTAL STUDENTS IN CAIRO UNIVERSITY: A CROSS-SECTIONAL STUDY overallStatus: NOT_YET_RECRUITING date: 2... |
There were some researches about oral health knowledge, behaviour and attitude in correlation to socio-demographic data, of dental students in other countries, but little was known in Egypt. Dental students are expected to play a critical role in instructing public oral health for improving their patient's, families, a... |
<|newrecord|> nctId: NCT06389357 id: 1305G2024 briefTitle: Return to School Adaptation Programme for Children With Cancer acronym: web-based overallStatus: NOT_YET_RECRUITING date: 2024-07-01 date: 2024-09-06 date: 2024-11-30 date: 2024-04-29 date: 2024-04-29 name: Gazi University class: OTHER briefSummary: This study ... |
H1: Is there a significant difference in children's social anxiety scores before and after the back-to-school adaptation programme? H2: Is there a significant difference in children's coping scores before and after the back-to-school adaptation programme? H3: Is there a significant difference in children's readiness to... |
<|newrecord|> nctId: NCT06389344 id: lk20240401 briefTitle: Effect of Esketamine on Conscious State in Patients With pDoC overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2025-12-31 date: 2026-06-30 date: 2024-04-29 date: 2024-04-29 name: Beijing Tiantan Hospital class: OTHER briefSummary: The goal of this clin... |
Participants will be patients with prolonged disorders of consciousness undergoing surgery with general anesthesia at Beijing Tiantan Hospital. 0.3mg/kg esketamine or saline will be infused will be infused intravenously at a constant speed within 30 min after tracheal intubation/pneumatectomy fixation. Coma recovery sc... |
<|newrecord|> nctId: NCT06389331 id: IRC/1971/020 briefTitle: Study on Effects of Defect Closure in Laparoscopic Repair of Direct Inguinal Hernia overallStatus: COMPLETED date: 2020-09-01 date: 2021-06-30 date: 2021-08-31 date: 2024-04-29 date: 2024-04-29 name: B.P. Koirala Institute of Health Sciences class: OTHER bri... |
<|newrecord|> nctId: NCT06389318 id: RC 29-11-2023 briefTitle: Buccal Midazolam Versus Intranasal Dexmedetomidine Plus Oral Chloral Hydrate in Inguinal Hernia Repair overallStatus: COMPLETED date: 2023-03-26 date: 2024-03-26 date: 2024-04-24 date: 2024-04-29 date: 2024-04-29 name: Benha University class: OTHER briefSum... |
<|newrecord|> nctId: NCT06389305 id: BJGBYY-IIT-LCYJ-2024-012 briefTitle: CIK Cell Therapy for Relapsed or Refractory Acute B-Lymphoblastic Leukemia: Prognostic Impact on Patients With Early CAR-T Cell Dysfunction overallStatus: RECRUITING date: 2024-05-01 date: 2025-04-30 date: 2026-04-30 date: 2024-04-29 date: 2024-0... |
<|newrecord|> nctId: NCT06389292 id: APG2575AG301 briefTitle: A Pivotal Phase 3 Study of APG-2575 (Lisaftoclax) Combined With Azacytidine in the Treatment of Acute Myeloid Leukemia overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2028-05-25 date: 2029-03-26 date: 2024-04-29 date: 2024-04-29 name: Ascentage Pharma ... |
<|newrecord|> nctId: NCT06389279 id: 2023-18/11 briefTitle: The Effect of Facial Plane Blocks on Postoperative Recovery Quality in Hip Surgery overallStatus: NOT_YET_RECRUITING date: 2024-04-24 date: 2024-09-24 date: 2024-10-24 date: 2024-04-29 date: 2024-04-29 name: Antalya Training and Research Hospital class: OTHER_... |
<|newrecord|> nctId: NCT06389266 id: 221550 briefTitle: Network-Targeted Neuromodulation for Nicotine Dependence in Schizophrenia overallStatus: RECRUITING date: 2023-06-15 date: 2029-01-10 date: 2029-01-10 date: 2024-04-29 date: 2024-04-29 name: Vanderbilt University Medical Center class: OTHER briefSummary: The goal ... |
1. Can rTMS change functional connectivity in brain circuits associated with nicotine use? |
2. Are those rTMS-induced changes in functional connectivity related to craving? |
Participants will complete tasks assessing their cognitive performance and craving before and after each week of TMS. Researchers will compare the effect of each TMS intervention on participants with and without psychosis to see if one type of TMS has an effect on nicotine craving. conditions: Schizophrenia conditions:... |
<|newrecord|> nctId: NCT06389253 id: HTSW1 briefTitle: Subtalar Extra-articular Screw Arthroereisis overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2025-05 date: 2025-05 date: 2024-04-29 date: 2024-04-29 name: Università Vita-Salute San Raffaele class: OTHER briefSummary: The aim of the study is to investigate th... |
<|newrecord|> nctId: NCT06389240 id: 160848 briefTitle: Early Weight Bearing in Unicondylar Tibial Plateau Fractures overallStatus: ACTIVE_NOT_RECRUITING date: 2022-12-21 date: 2025-12 date: 2025-12 date: 2024-04-29 date: 2024-04-29 name: University of Utah class: OTHER briefSummary: The investigators aim of the study ... |
It is assumed that earlier mobilization does not lead to an increase in the complications - in particular osteosynthesis failure and infections -, but leads to improved patient satisfaction, reduced return to work/sports times, and has a positive impact on the overall outcome conditions: Early Mobilization studyType: O... |
<|newrecord|> nctId: NCT06389227 id: 0433611 briefTitle: Developing the Physical Performance in Youth Soccer: Short-term Effect of Dynamic-Ecological Versus Traditional Training Approach for Sub-élite U13 Players: An Ecological Exploratory Cluster Randomised Trial overallStatus: COMPLETED date: 2023-10-15 date: 2023-10... |
<|newrecord|> nctId: NCT06389214 id: ADX-102-DED-030 briefTitle: A Phase 3 Clinical Trial to Assess the Efficacy and Safety of Subjects With Dry Eye Disease overallStatus: RECRUITING date: 2024-04-09 date: 2024-12-31 date: 2024-12-31 date: 2024-04-29 date: 2024-04-29 name: Aldeyra Therapeutics, Inc. class: INDUSTRY bri... |
<|newrecord|> nctId: NCT06389201 id: 2024HCQ briefTitle: Pretreatment With HCQ Before Radiotherapy and Chemotherapy in Advanced NPC Patients overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2024-12-31 date: 2026-12-31 date: 2024-04-29 date: 2024-04-29 name: Affiliated Hospital of Nantong University class: OTHER... |
Pretreatment with an autophagy inhibitor (HCQ) before chemotherapy and radiotherapy could prevent formation of therapy-induced dormant polyploid giant cancer cells, thereby reducing recurrence and metastasis of nasopharyngeal carcinoma. conditions: Nasopharyngeal Carcinoma studyType: INTERVENTIONAL phases: NA allocatio... |
<|newrecord|> nctId: NCT06389188 id: JVT003 briefTitle: Effectiveness of Cervical Osteopathic Manipulation in Patients With Whiplash overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2024-09-01 date: 2024-10-01 date: 2024-04-29 date: 2024-04-29 name: Universidad Miguel Hernandez de Elche class: OTHER name: Conso... |
<|newrecord|> nctId: NCT06389175 id: BON001 id: KR 4555/10-1 type: OTHER_GRANT domain: Deutsche Forschungsgemeinschaft (DFG) briefTitle: Non-invasive Vagus Nerve Stimulation as a Tool to Modulate Stomach-Brain Coupling in Depression overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2026-12 date: 2026-12 date: 2024-... |
<|newrecord|> nctId: NCT06389162 id: UNLV-2024-115 briefTitle: Dorsolateral Prefrontal Cortex Transcranial Direct Current and Muscle Fatigue Stimulation on Muscle Fatigue overallStatus: ENROLLING_BY_INVITATION date: 2024-04-04 date: 2024-08-31 date: 2024-09-30 date: 2024-04-29 date: 2024-04-29 name: University of Nevad... |
1. Does tDCS of the left DLPFC increase the time that a fatiguing contraction can be maintained? |
2. Does tDCS of the left DLPFC decrease the rate of increase of muscle activity, force error, and standard deviation of force during a fatiguing contraction. |
Researchers will compare tDCS of the left DLPFC to a SHAM stimulation (a type of stimulation that feels like real tDCS but does not elicit physiological effects) to see if tDCS of the left DLPFC works to reduce the progression of muscle fatigue. |
Participants will: |
Performing two experimental sessions held 3-10 days apart (usually 7 days) Perform a 9 hole pegboard test, maximum voluntary contractions, and a fatiguing contraction. conditions: Fatigue studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER primaryPurpose: TREATMENT masking: TRIPLE m... |
<|newrecord|> nctId: NCT06389149 id: 0165-24-FB briefTitle: Leg Exercise Assistive Paddling (LEAP) Therapy for Peripheral Artery Disease overallStatus: NOT_YET_RECRUITING date: 2024-08 date: 2025-08 date: 2025-08 date: 2024-04-29 date: 2024-04-29 name: University of Nebraska class: OTHER briefSummary: 1) The purpose of... |
<|newrecord|> nctId: NCT06389136 id: M24-601 briefTitle: A Study of Upadacitinib in Adult Participants With Moderate-to-Severe Atopic Dermatitis and Inadequate Response to Dupilumab acronym: Switch-Up overallStatus: NOT_YET_RECRUITING date: 2024-05-24 date: 2025-08-22 date: 2026-03-09 date: 2024-04-29 date: 2024-04-29 ... |
Upadacitinib is an approved drug for the treatment of moderate to severe atopic dermatitis (AD). This study is conducted in 2 periods. During Period 1, participants are randomly assigned into 1 of 2 groups called treatment arms to receive upadacitinib Dose A or dupilumab Dose A. Based on the participants response to up... |
The study is comprised of a 35-day Screening Period, an 8-week Open-Label Period 1 and a 24-week Open-Label Period 2 for participants that completed Period 1. Participants will receive upadacitinib oral tablets once daily or dupilumab subcutaneous (SC) injection every other week for 32 weeks and followed for 30 days. |
There may be higher treatment burden for participants in this trial compared to their standard of care. Participants will attend regular visits during the study at a hospital or clinic. The effect of the treatment will be checked by medical assessments, blood tests, checking for side effects and completing questionnair... |
<|newrecord|> nctId: NCT06389123 id: 1788760 briefTitle: Molecularly Targeted Theranostic Approach for the Detection and Treatment of Metastatic Carcinomas overallStatus: RECRUITING date: 2024-04-01 date: 2027-03-31 date: 2028-03-31 date: 2024-04-29 date: 2024-04-29 name: University of California, Davis class: OTHER na... |
<|newrecord|> nctId: NCT06389110 id: SOPH201-1023/III briefTitle: Study to Evaluate the Efficacy of Alleance® (Atropine Sulfate 0.01%) as a Treatment to Delay Myopia and Axial Ocular Elongation in Children. overallStatus: NOT_YET_RECRUITING date: 2024-12-30 date: 2027-06-30 date: 2027-06-30 date: 2024-04-29 date: 2024-... |
<|newrecord|> nctId: NCT06389097 id: J23152 id: IRB00411454 type: OTHER domain: JHM IRB id: P01CA272222 type: NIH link: https://reporter.nih.gov/quickSearch/P01CA272222 briefTitle: SPECT Imaging for Pharmacokinetics and dosimEtry Towards TREATment Optimization acronym: (SEEtoTREAT) overallStatus: NOT_YET_RECRUITING dat... |
<|newrecord|> nctId: NCT06389084 id: 179939 briefTitle: Parents Together: Supporting Parents to Promote Healthy Behaviours in Children overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2025-03-31 date: 2025-12-31 date: 2024-04-29 date: 2024-04-29 name: The Hospital for Sick Children class: OTHER briefSummary: Th... |
<|newrecord|> nctId: NCT06389071 id: PLS001 briefTitle: Laser Treatment for Lichen Sclerosus overallStatus: RECRUITING date: 2024-03-01 date: 2025-12-20 date: 2025-12-30 date: 2024-04-29 date: 2024-04-29 name: Sciton class: INDUSTRY briefSummary: Fractional ablative laser treatment for Lichen Sclerosus lesion condition... |
<|newrecord|> nctId: NCT06389058 id: G00014538 briefTitle: Using NLP and Neural Networks to Autonomously Identify Severe Asthma and Determine Study Eligibility in a Large Healthcare System overallStatus: ACTIVE_NOT_RECRUITING date: 2023-05-01 date: 2024-07-01 date: 2026-11 date: 2024-04-29 date: 2024-04-29 name: San Di... |
Primary Objectives Please ensure you detail primary objectives Aim 1. Determine and validate a diagnosis of severe asthma (SA) using predictive features obtained from the Scripps Health EHR. |
* Aim 1a: Use ML applied to structured EHR data to predict SA. Use the opinion of 2 specialty-trained physicians and ATS guidelines to determine model accuracy. |
* Aim 1b: Use NLP applied to unstructured text to predict SA. Determine model accuracy as above in Aim 1a. |
* Aim 1c: Use a combination of ML applied to structured data to predict SA. Determine model accuracy as above in Aim 1a. conditions: Severe Asthma studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: CROSS_SECTIONAL count: 31795 type: ACTUAL name: Recommendation for the diagnoses and treatment of Severe ... |
<|newrecord|> nctId: NCT06389045 id: EUS briefTitle: Profopol and Remifentanil Sedation in Endoscopic Ultrasonography overallStatus: RECRUITING date: 2024-04-24 date: 2024-06-24 date: 2024-07-01 date: 2024-04-29 date: 2024-04-29 name: Samsun University class: OTHER briefSummary: Endoscopic ultrasonography (EUS) is an e... |
<|newrecord|> nctId: NCT06389032 id: 21041503 id: 1R01AG079128-01A1 type: NIH link: https://reporter.nih.gov/quickSearch/1R01AG079128-01A1 briefTitle: PERSEVERE in Lewy Body Dementia: A Randomized, Controlled Trial of Peer Mentor Support and Caregiver Education overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2... |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.