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After enrollment, subjects will undergo a baseline Hypoglycemia Recovery Procedure (with glucagon rescue). Subjects will then receive volagidemab subcutaneously (SC) once weekly for 6 weeks. At the end of the treatment phase, subjects will undergo a second Hypoglycemia Recovery Procedure. Subjects will be followed for ... |
<|newrecord|> nctId: NCT06272682 id: 6669 briefTitle: Corticosteroids in Carpal Tunnel Syndrome. Prospective Randomised Controlled Non-inferiority Study overallStatus: RECRUITING date: 2023-07-17 date: 2024-08-11 date: 2025-10-11 date: 2024-02-22 date: 2024-02-22 name: Hospital Italiano de Buenos Aires class: OTHER bri... |
The main questions it aims to answer are: |
* What is the effectiveness of intramuscular injection of corticosteroids compared to local infiltration in the treatment of mild/moderate carpal tunnel syndrome? |
* What are the adverse effects and application site pain associated with each route of administration? |
Patients who meet the inclusion criteria will be asked to participate in the study and sign an informed consent form. |
The Redcap randomizer will be used to assign the patient to one of the branches. |
Researchers will compare |
* Branch A: patients treated with local corticosteroid infiltration in carpal tunnel under ultrasound |
* Branch B: patients treated with intramuscular corticosteroid injection. |
Researchers will: |
* Compare Boston Carpal Tunnel Questionnaire score at 1.5 months, 3 months, 6 months and 12 months post-procedure. |
* Describe adverse reactions associated with the route of administration. |
* Compare the pain at the site of application associated with the route of administration. conditions: Carpal Tunnel Syndrome studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Prospective, randomised, controlled, non-inferiority analytical study primar... |
<|newrecord|> nctId: NCT06272669 id: HSEARS20220216004 briefTitle: Cumulative and Booster Effects of Multisession Prefrontal tDCS in Adolescents With ASD overallStatus: RECRUITING date: 2022-06-02 date: 2025-09 date: 2025-12 date: 2024-02-22 date: 2024-02-22 name: The Hong Kong Polytechnic University class: OTHER brief... |
<|newrecord|> nctId: NCT06272656 id: AKR-TACE-001 briefTitle: Evaluation of AKR1B10 as a New Marker for Interventional Therapy of Hepatocellular Carcinoma overallStatus: RECRUITING date: 2024-04-01 date: 2025-06-30 date: 2025-06-30 date: 2024-02-22 date: 2024-04-03 name: Hebei Medical University Third Hospital class: O... |
<|newrecord|> nctId: NCT06272643 id: EPIC36-EMPERATRIZ briefTitle: Comparison Between Optical Coherence Tomography and Intravascular Ultrasound for Intermediate Left Main Coronary Artery Lesions acronym: EMPERATRIZ overallStatus: RECRUITING date: 2024-04-04 date: 2025-01-20 date: 2026-01-20 date: 2024-02-22 date: 2024-... |
<|newrecord|> nctId: NCT06272630 id: DW_DWJ1464401 briefTitle: Study to Evaluate the Efficacy and Safety of DWJ1464 in Patients With Chronic Liver Disease overallStatus: ENROLLING_BY_INVITATION date: 2023-02-06 date: 2024-05-31 date: 2024-08-31 date: 2024-02-22 date: 2024-04-26 name: Daewoong Pharmaceutical Co. LTD. cl... |
<|newrecord|> nctId: NCT06272617 id: 2023-960 briefTitle: Acupuncture for Prevention and Treatment of Oral-related Complications Caused by Radiotherapy for Head and Neck Cancer overallStatus: RECRUITING date: 2023-07-25 date: 2024-07-24 date: 2025-07-24 date: 2024-02-22 date: 2024-02-22 name: West China Hospital class:... |
<|newrecord|> nctId: NCT06272604 id: 2024-IRB-0015-P-01 briefTitle: Exercise Rehabilitation for Children With Asthma overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2027-04-01 date: 2027-10-01 date: 2024-02-22 date: 2024-02-22 name: The Children's Hospital of Zhejiang University School of Medicine class: OTHER... |
<|newrecord|> nctId: NCT06272591 id: IRBN1192023/CHUSTE briefTitle: Comparison of Patient Satisfaction With Home Induction and In-patient Induction. overallStatus: RECRUITING date: 2023-11-20 date: 2024-05 date: 2024-05 date: 2024-02-22 date: 2024-02-22 name: Centre Hospitalier Universitaire de Saint Etienne class: OTH... |
Induced labour concerns 25.8% of pregnant women in France, according to the latest National Perinatal Survey 2021. This rate is rising steadily, since in 2016 induction concerned 22% of pregnancies. There are many medical indications for induction, both maternal and foetal. Induced labour in hospitals is beginning to r... |
Cervical ripening can be a difficult experience for women, with a feeling of loss of control at this crucial stage. The duration of induction is one of the factors that women would like to see changed when asked about the aftermath of induction. The option of inducing at home might seem to improve women's experience an... |
<|newrecord|> nctId: NCT06272578 id: 20021405 briefTitle: Screen CardRen - A Cross-sectional Observational Cohort Study overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2025-02-27 date: 2025-06-30 date: 2024-02-22 date: 2024-02-23 name: Charite University, Berlin, Germany class: OTHER name: AstraZeneca briefSum... |
<|newrecord|> nctId: NCT06272565 id: 2023KYPJ292 briefTitle: Exploring the Interaction Between Metabolic Disorders and NLPR3 Inflammasome Activation in DR Inflammatory Damage acronym: DR overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2026-12-30 date: 2026-12-30 date: 2024-02-22 date: 2024-02-22 name: Zhongsha... |
<|newrecord|> nctId: NCT06272552 id: PI21-00026 id: 2021/10182/I type: OTHER domain: CEIm Parc de Salut Mar briefTitle: Implementing PROMs and PREMs in Routine Clinical Care: Assessment of Requirements and Impact acronym: PROMs & PREMs overallStatus: RECRUITING date: 2023-10-25 date: 2027-10 date: 2027-10 date: 2024-02... |
Objective: To evaluate the efficacy of the implementation of PROMs and PREMs in routine clinical care for improving health outcomes and satisfaction with health management. |
Design: Randomized control trial. Setting: In and outpatient departments of a public hospital in Spain. |
Participants: 1,440 adult patients managed for breast cancer, prostate cancer, chronic kidney disease, or bariatric surgery. |
Intervention: Patients will monthly complete, through an App from their smartphones, PROMs and PREMs (arm A, n=480), or only PREMs (arm B, n=480). Responses to PROMs will be transformed into a graphic summary, accessible for physicians and patients at the follow-up visits of the project (9 and 18 months after recruitme... |
Main outcome measures: Comparison of change among arms on the assessment variables - such as health-related quality of life (EQ-5D-5L), satisfaction with care, or patient-professionals communication. These constructs will be measured at recruitment and at follow up visits for all patients, regardless of their arm alloc... |
Expected results: Incorporating PROMs and PREMs in routine clinical care may improve patients\' and health professionals\' experiences on health care, as well as improve patients\' health. conditions: PROMs conditions: PREMs conditions: Implementation Research conditions: Impact Evaluation studyType: INTERV... |
<|newrecord|> nctId: NCT06272539 id: 2023 101435 briefTitle: Spinal Cord Stimulation Combined With Exercise in Persistent Spinal Pain Syndrome overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2026-01-01 date: 2026-01-01 date: 2024-02-22 date: 2024-02-28 name: Fundación Universidad Católica de Valencia San Vicen... |
<|newrecord|> nctId: NCT06272526 id: SOCIALANX_1 briefTitle: Internet-Based Self-Help Intervention for Social Anxiety Symptoms overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2024-10-01 date: 2024-12-31 date: 2024-02-22 date: 2024-02-22 name: Anadolu University class: OTHER briefSummary: This study is a random... |
The intervention program will be offered to treatment group participants (guided) through the website https://kendikendineyardim.org, the unique online self-help platform in Turkey. Participants in the web-based treatment group will receive feedback message within 24 hours after each completed module from the guides. c... |
<|newrecord|> nctId: NCT06272513 id: ProAct-HNC-02 briefTitle: Influencing Factors for Physical Activity in People With Head and Neck Cancer acronym: ProAct-HNC overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2025-03-31 date: 2025-06-30 date: 2024-02-22 date: 2024-02-26 name: Kantonsspital Winterthur KSW class: O... |
Individual interviews will be conducted with people affected by head and neck cancer and focus group interviews will be held with significant others of people being affected to answer the following research questions: |
* What capabilities and opportunities for physical activity participation do people with advanced head and neck cancer experience? |
* What motivates people with advanced head and neck cancer to be physically active? |
* How do significant others view capabilities, opportunities, and motivation for physical activity participation in people with head and neck cancer? |
The interviews will be transcribed verbatim and analysed with a structuring content analysis approach. conditions: Advanced Head and Neck Squamous Cell Carcinoma studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: PROSPECTIVE count: 20 type: ESTIMATED measure: interview transcripts measure: personal inf... |
<|newrecord|> nctId: NCT06272500 id: 2024-KY-0146-001 briefTitle: Exploring Methods for Treating Hypergastrinemia in Patients With Autoimmune Gastritis overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2024-05-31 date: 2024-05-31 date: 2024-02-22 date: 2024-02-22 name: Jianning Yao class: OTHER briefSummary: Aut... |
Gastric neuroendocrine tumors (g-NETs), also known as gastric carcinoids, account for approximately 23% of gastrointestinal and pancreatic neuroendocrine tumors. Clinically, g-NETs are mainly classified into three types. Type III is typically sporadic tumors associated with normal gastrin levels and poor prognosis. Alt... |
Due to the destruction of gastric glands (including parietal and chief cells) in AAG patients, there is a deficiency in intrinsic factor, gastric acid, and a decrease in pepsinogen I (PG-I) levels. Insufficient gastric acid secretion leads to a compensatory increase in gastrin secretion by G cells in the gastric antrum... |
<|newrecord|> nctId: NCT06272487 id: ALN-AGT01-007 briefTitle: Zilebesiran as Add-on Therapy in Patients With High Cardiovascular Risk and Hypertension Not Adequately Controlled by Standard of Care Antihypertensive Medications (KARDIA-3) acronym: KARDIA-3 overallStatus: RECRUITING date: 2024-02-29 date: 2025-03-20 date... |
<|newrecord|> nctId: NCT06272474 id: 0266-07/2021 - 18/07/2021 briefTitle: Virtual Reproduction of Mandibular Movement for Assessing Occlusal Interferences and Adjustments overallStatus: COMPLETED date: 2022-09-11 date: 2023-12-09 date: 2023-12-09 date: 2024-02-22 date: 2024-02-22 name: Hams Hamed Abdelrahman class: OT... |
The aim of this study: This study will clinically assess the reliability of the virtual reproduction of mandibular movement for detecting occlusal interferences and adjustments of designed and milled CAD-CAM zirconia crowns using a digital occlusal analyzer. |
Materials and methods: Intraoral optical impression will be made for thirteen selected patients with endodontically treated maxillary first premolars after abutment preparation followed by buccal and lateral interocclusal records taking. Two zirconia crowns will be fabricated for each patient following regular digital ... |
<|newrecord|> nctId: NCT06272461 id: UTEM ELKI briefTitle: Comparison of Intravenous Lidocaine vs Ketamine in Colorectal Surgery overallStatus: RECRUITING date: 2023-10-01 date: 2024-05-30 date: 2024-06-30 date: 2024-02-22 date: 2024-04-16 name: University Tunis El Manar class: OTHER briefSummary: Patients undergoing o... |
For the IV-Lido group, patients received a loading dose of Lidocaine than a continuous infusion over twenty-four hours. |
For the IV-Keta goup, patients received a loading dose of Ketamine than a continuous injection of Ketamine over twenty-four hours. |
Plasma concentrations of Interleukin-6(IL-6) were measured preoperatively before anesthetic induction and at twenty-four hour post operatively. conditions: Colorectal (Colon or Rectal) Cancer conditions: Inflammation studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionMod... |
<|newrecord|> nctId: NCT06272448 id: CERM2022-27 21042022 briefTitle: teleRehabilitation for pAtients With ParkInson's Disease at Any mOment acronym: RAPIDO overallStatus: RECRUITING date: 2022-11-15 date: 2024-05-31 date: 2024-05-31 date: 2024-02-22 date: 2024-02-22 name: Università Politecnica delle Marche class: OTH... |
<|newrecord|> nctId: NCT06272435 id: PRO-FY2024-64 briefTitle: Beverage Hydration Index: Assessment of Four Rehydration Solutions overallStatus: RECRUITING date: 2023-12-23 date: 2024-05-31 date: 2024-05-31 date: 2024-02-22 date: 2024-02-22 name: University of Memphis class: OTHER briefSummary: No studies to date to ev... |
<|newrecord|> nctId: NCT06272422 id: 2022/0472 id: 2023-A00358-37 type: OTHER domain: IDRCB - ANSM ID briefTitle: Comparison of the Restoration of Hip Biomechanical Parameters by CT Measurement Between the 3 Surgical Techniques: RSA/Minihip/THA - Hip Replacement: 3D Planning acronym: HIP3D overallStatus: NOT_YET_RECRUI... |
To this end, two types of examination are carried out, both of which are used in current practice: |
* Pre-operatively: EOS radiography |
* Post-operatively: EOS radiograph and CT scan |
Inclusion (m-3; m-1) : |
* Patient information at pre-operative visit |
* Non-opposition of patient, family member or legal guardian, if applicable |
* Questionnaires and clinical examination (standard management) |
* EOS during anesthetic consultation |
Follow-up visit (m+3): |
- Post-operative follow-up consultation EOS and CT scan (1 week prior to visit) + questionnaire and clinical examination |
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