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<|newrecord|> nctId: NCT06276413 id: REBRA id: REBRA type: REGISTRY domain: REBRA briefTitle: REgistRy BRAnch goRE EndopRosthEsis acronym: REBRA overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2025-12-31 date: 2030-12-31 date: 2024-02-26 date: 2024-02-26 name: University Hospital Padova class: OTHER briefSumma... |
<|newrecord|> nctId: NCT06276400 id: 4-24-0023:1 briefTitle: LPFC Organization in Emotion-Duration Difference Estimation overallStatus: RECRUITING date: 2024-01-29 date: 2028-03-31 date: 2028-03-31 date: 2024-02-26 date: 2024-03-05 name: University of California, Santa Barbara class: OTHER briefSummary: To support opti... |
The goal of this study is to examine how specific brain regions track both emotional and temporal information of dynamic emotional events to inform other related brain regions to guide goal-oriented and context-appropriate actions. The investigators will scan healthy human participants using functional MRI (fMRI) while... |
<|newrecord|> nctId: NCT06276387 id: K23AT011768-01 type: NIH link: https://reporter.nih.gov/quickSearch/K23AT011768-01 id: K23AT011768 type: NIH link: https://reporter.nih.gov/quickSearch/K23AT011768 briefTitle: Defining Stress REsilience And Mindfulness Effects in Rheumatoid Arthritis acronym: DREAMER overallStatus: ... |
* Assess patient satisfaction with a mindfulness course |
* Identify barriers to participation in, or completion of, a mindfulness course |
* Gather initial information to understand how a mindfulness course impacts RA symptoms |
Participants will: |
* Complete online questionnaires |
* Attend two in-person study visits, involving a brief joint exam and blood draw |
* Roughly half the participants will have the chance to participate in an 8-week online mindfulness course |
* Roughly half the participants will be invited to participate in an online focus group following completion of the mindfulness course |
Researchers will compare those in the mindfulness course with those receiving standard care in preparation for a larger future study to see how mindfulness impacts stress and inflammation in individuals with RA. conditions: Arthritis, Rheumatoid studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionMo... |
<|newrecord|> nctId: NCT06276374 id: SMC 2023-12-107 briefTitle: Highest Efficacy of Dual Antiplatelet Therapy After Carotid Artery Stenting in High Bleeding Risk Patients overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2026-11-30 date: 2027-12-31 date: 2024-02-26 date: 2024-02-26 name: Woo-Keun Seo class: OTH... |
<|newrecord|> nctId: NCT06276361 id: ROV-QUAR-2023-01 briefTitle: Pharmacokinetics, Safety and Tolerability of Different Formulations and Dose Strengths of Quarterly Risperidone (QUAR) in Patients With Schizophrenia acronym: QUARTZ overallStatus: RECRUITING date: 2023-09-26 date: 2026-05 date: 2026-05 date: 2024-02-26 ... |
<|newrecord|> nctId: NCT06276348 id: 20226892 briefTitle: Newborn Genomic Sequencing Pilot Study overallStatus: ACTIVE_NOT_RECRUITING date: 2023-03-13 date: 2024-02-28 date: 2024-09 date: 2024-02-26 date: 2024-03-04 name: Rady Pediatric Genomics & Systems Medicine Institute class: OTHER briefSummary: The goal of this c... |
* What is the diagnostic yield of diagnostic whole genome sequencing (DWGS) in this population? |
* What is the diagnostic sensitivity and specificity of BeginNGS and whole exome sequencing (WES) as compared to DWGS? |
* What are the potential issues related to implementing DWGS in this population? |
Enrolled newborns will have a blood sample taken and will receive three tests: |
* DWGS |
* BeginNGS |
* WES conditions: Genetic Disease studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: Single group, multiple interventions. All enrollees receive all interventions. primaryPurpose: SCREENING masking: NONE count: 120 type: ACTUAL name: Whole genome sequencing... |
<|newrecord|> nctId: NCT06276335 id: IRAS:322440 briefTitle: Influence of Timing of Implant Placement on Early Healing Molecular Events overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2026-04-30 date: 2026-05-30 date: 2024-02-23 date: 2024-03-08 name: Queen Mary University of London class: OTHER name: Universi... |
The primary objective of this study is to describe changes in the expression of inflammatory, angiogenesis and osseous biomarkers of saliva at 1, 3, 7, 15 and 30 days and of PICF at 3, 7, 15 and 30 days after immediate implant placement (IP) compared with delayed placement (DP). conditions: Dental Implant conditions: H... |
<|newrecord|> nctId: NCT06276322 id: HU-FTR-SZK-01 briefTitle: Assessment of All Spine Segments ın Individuals With Low Back Pain overallStatus: RECRUITING date: 2023-12-01 date: 2024-03-20 date: 2024-12-31 date: 2024-02-23 date: 2024-03-07 name: Hacettepe University class: OTHER briefSummary: The aim of the study is t... |
<|newrecord|> nctId: NCT06276309 id: NECC2401 briefTitle: Protein Molecular Characteristics and Prognosis of Cervical Neuroendocrine Tumors overallStatus: RECRUITING date: 2024-02-01 date: 2024-06-30 date: 2024-06-30 date: 2024-02-23 date: 2024-02-23 name: Fujian Maternity and Child Health Hospital class: OTHER briefSu... |
<|newrecord|> nctId: NCT06276296 id: 0001 briefTitle: Heart Rate Variability After Ablation overallStatus: RECRUITING date: 2023-03-01 date: 2024-08-31 date: 2024-10-01 date: 2024-02-23 date: 2024-02-23 name: Charles University, Czech Republic class: OTHER name: Vascular surgery, University hospital Královské Vinohrady... |
<|newrecord|> nctId: NCT06276283 id: DZ2022E0006 briefTitle: DZD9008 In Combination With Bevacizumab in Locally Advanced or Metastatic NSCLC Patients With EGFR Mutation (WU-KONG29) overallStatus: RECRUITING date: 2023-02-15 date: 2025-05-31 date: 2026-02-28 date: 2024-02-23 date: 2024-02-23 name: Dizal Pharmaceuticals ... |
<|newrecord|> nctId: NCT06276270 id: PT-MUC-1_05-21 briefTitle: Multi-centre, Open-label, First-in-man Study With Mucopad HA overallStatus: RECRUITING date: 2023-12-12 date: 2024-12-31 date: 2024-12-31 date: 2024-02-23 date: 2024-02-23 name: Contipro Pharma a.s. class: OTHER briefSummary: The device´s intended use is t... |
<|newrecord|> nctId: NCT06276257 id: 2024-7301 briefTitle: Paravertebral Block for Mastectomy With Immediate Reconstruction overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2025-07 date: 2025-12 date: 2024-02-23 date: 2024-02-23 name: CHU de Quebec-Universite Laval class: OTHER briefSummary: Following a mastectomy... |
The main objective of this study is to compare two analgesic modalities, namely BPV (study modality) and usual analgesia (control modality), in patients undergoing total mastectomy with immediate reconstruction under general anesthesia with the aim of to evaluate their functional pain score at 24, 48 and 72 hours follo... |
<|newrecord|> nctId: NCT06276244 id: NM040-GUP19002 briefTitle: Trial Readiness and Endpoint Assessment in Congenital and Childhood Myotonic Dystrophy acronym: GUP19002 overallStatus: ACTIVE_NOT_RECRUITING date: 2020-07-08 date: 2024-04 date: 2024-04 date: 2024-02-23 date: 2024-02-23 name: Fondazione Serena Onlus - Cen... |
<|newrecord|> nctId: NCT06276231 id: SalbuEase briefTitle: Nebulized Salbutamol in Acute Renal Colic overallStatus: NOT_YET_RECRUITING date: 2024-07-01 date: 2026-03-01 date: 2026-05-01 date: 2024-02-23 date: 2024-03-19 name: Oman Medical Speciality Board class: OTHER_GOV briefSummary: A Prospective, double blinded, Ra... |
Research Summary: |
INTRODUCTION: Pain is a common reason for individuals to seek health care, especially emergency care. Salbutamol has an effect for smooth muscle relaxation of the ureters. The administration of Salbuatmol has been shown to be safe and effective in the treatment of asthma exacerbation, but there have been no studies eva... |
METHOD: This is a double blinded randomized clinical controlled trial. Two hundred renal colic patients presenting to the emergency department will be randomized to intervention (10 mg nebulized salbutamol) and (10 ml neublized Normal saline) case groups. Both the groups will get the standard treatment (IM diclofenac 7... |
AIM: The aim of this study is to compare analgesic effects of Nebulized Salbutamol versus Placebo in adult patients with renal colic. |
PRIMARY OJECTIVES: Analgesic effects of Nebulized Salbutamol on the Numerical Rating scale (NRS). |
SECONDARY OBJECTIVES: Adverse Events, the need of rescue pain medications and time to discharge. |
PATEINT POPULATION: Adults (from age 18 to 60 years) who presents to emergency department (ED) at Armed force Hospital with acute flank pain suggestive of renal colic |
INTERVENTION: Single dose of Nebulized Salbutamol 10mg. |
CLINICAL MEASURMENT: Numerical pain Analog Scale will be assessed at 0,15,30, 45 and 60 minutes after intervention. Number and dosage of rescue medication, any reported events by patient or attending physician will be documented. |
OUTCOME: Decrease in pain measures by NRS pain score after Nebulized Salbutamol is given, tolerability and safety evaluation. conditions: Renal Colic studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: QUADRUPLE whoMasked: PARTICIPANT whoMasked: CAR... |
<|newrecord|> nctId: NCT06276218 id: PSU briefTitle: Efficacy of Self - Adjustable Clavicular Brace Versus Standard Clavicular Brace for Treatment of Mid Shaft Clavicle Fracture: A Randomized Controlled Study overallStatus: RECRUITING date: 2022-02-01 date: 2024-02-15 date: 2024-02-16 date: 2024-02-23 date: 2024-02-23 ... |
<|newrecord|> nctId: NCT06276205 id: 1037/RC/KEMU briefTitle: Vitamin D & Levothyroxine Combination Versus Levothyroxine on Lipid Profile in Hypothyroidism acronym: ViDaLLiT overallStatus: RECRUITING date: 2024-03-01 date: 2024-09-30 date: 2024-09-30 date: 2024-02-23 date: 2024-02-23 name: King Edward Medical Universit... |
The main question it aims to answer is: |
• whether adding Vitamin D to standard therapy has any additional benefits |
Participants will be given Vitamin D in replacement doses according to their pre-existing Vitamin D level in addition to levothyroxine. |
Researchers will compare them with another group receiving only levothyroxine to see how much lipids improve in them conditions: Hypothyroidism Primary conditions: Lipid Disorder conditions: Dyslipidemias studyType: INTERVENTIONAL phases: PHASE3 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATME... |
<|newrecord|> nctId: NCT06276192 id: 2023-01882-01 briefTitle: Digital Physiotherapy Treatment for Patients With Subacromial Pain Compared to Usual Physiotherapy in Primary Care acronym: diSAID overallStatus: NOT_YET_RECRUITING date: 2024-02-26 date: 2026-03-26 date: 2028-03-26 date: 2024-02-23 date: 2024-02-23 name: R... |
The main question this clinical trial aims to answer are: |
- Can the diSAID improve shoulder function and reduce pain for patients with subacromial pain in primary care? conditions: Subacromial Pain Syndrome conditions: Shoulder Pain conditions: Rotator Cuff Syndrome studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescri... |
<|newrecord|> nctId: NCT06276179 id: KFSIRB200-97 briefTitle: Epidural Oxycodone for Pain Management for Lower Limb Amputation overallStatus: RECRUITING date: 2024-02-24 date: 2024-08-01 date: 2024-08-01 date: 2024-02-23 date: 2024-02-28 name: Kafrelsheikh University class: OTHER briefSummary: The aim of this study is ... |
<|newrecord|> nctId: NCT06276166 id: 72374215 briefTitle: Trajectory of Frailty and Cognitive Dysfunction in Older Adults overallStatus: NOT_YET_RECRUITING date: 2024-03-15 date: 2026-06-30 date: 2026-12-31 date: 2024-02-23 date: 2024-03-07 name: Zheng Li class: OTHER briefSummary: To explore the heterogeneity of the d... |
<|newrecord|> nctId: NCT06276153 id: CRGGCext briefTitle: Construction of Multicenter Retrospective Registry Cohort Database for Gallbladder Cancer acronym: CRGGCext overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2027-02-28 date: 2029-02-28 date: 2024-02-23 date: 2024-02-28 name: RenJi Hospital class: OTHER b... |
<|newrecord|> nctId: NCT06276140 id: 4/23/2-4661/2-9 briefTitle: Iron-deficiency Anaemia and Its Impact on Recovery After Colorectal Cancer Surgery acronym: ID-COLO overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2026-01 date: 2026-01 date: 2024-02-23 date: 2024-02-28 name: Oncology Institute of Vojvodina class: ... |
* whether the presence of preoperative iron deficiency anaemia leads to a poorer quality of postoperative recovery in patients undergoing colorectal cancer surgery |
* whether different combinations of complete blood count parameters (red blood cell indices) could be suitable diagnostic tools for the detection of iron deficiency in the latent stage (without laboratory-confirmed anaemia) in colorectal cancer patients. |
Blood samples for laboratory analyses will be collected from each study patient admitted to the surgical ward one day prior to elective surgery and on the first postoperative day during the stay in the intensive care unit. The pre-operative laboratory analyses include a complete blood count and serum iron status parame... |
Data about overall morbidity, intraoperative complications, quality of postoperative recovery, red blood cell transfusion rate, all-cause infection rate, antibiotic usage, as well as length of hospital stay will be collected. |
The researchers will compare the group of patients with iron deficiency anaemia, the group of patients with iron deficiency in the latent stage and the control group to determine whether patients with iron deficiency have a higher incidence of perioperative complications and impaired recovery after surgery. The researc... |
<|newrecord|> nctId: NCT06276127 id: MERC301123 briefTitle: Oral Bisoprolol Vs IV Diltiazem in Atrial Fibrillation or Flutter With Rapid Ventricular Rate. acronym: BisoAF overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2026-04 date: 2026-06 date: 2024-02-23 date: 2024-03-05 name: Oman Medical Speciality Board cla... |
METHOD: This study is a randomized controlled trial targeting patients who present to the emergency room with symptomatic atrial fibrillation or flutter and rapid ventricular response requiring intervention. Participants will be split into two groups and undergo continuous monitoring of vital signs and regular electroc... |
AIM: Evaluate the efficacy and safety of oral bisoprolol in treating atrial fibrillation or atrial flutter with rapid ventricular response in an emergency department setting. |
PRIMARY OJECTIVES: The primary efficacy outcome will be evaluated by achieving a HR\<110 beats per minute or a decrease ≥20% of baseline HR at 60 minutes. The primary safety outcome measures are HR \< 60 bpm and SBP \< 95 mm Hg. |
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