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<|newrecord|> nctId: NCT06379035 id: Protozoa in CRC patients briefTitle: Blastocystis and Cryptosporidium Infection in Colorectal Cancer Patients overallStatus: NOT_YET_RECRUITING date: 2024-11-01 date: 2025-11-01 date: 2025-12-31 date: 2024-04-23 date: 2024-04-23 name: Assiut University class: OTHER briefSummary: 1. ... |
2. Detect the effect of Blastocystis and Cryptosporidium infection on various cytokines level in CRC patients that may be involved in the tumor progression. conditions: Blastocystis Infection conditions: Cryptosporidium Infection conditions: Colorectal Cancer studyType: OBSERVATIONAL observationalModel: COHORT timePers... |
<|newrecord|> nctId: NCT06379022 id: AUTh-29/21-11-2018 briefTitle: Proteomic Analysis of Newly Restored Single Implants overallStatus: COMPLETED date: 2018-12-03 date: 2019-11-29 date: 2019-11-29 date: 2024-04-23 date: 2024-04-23 name: Aristotle University Of Thessaloniki class: OTHER name: Karolinska Institutet brief... |
<|newrecord|> nctId: NCT06379009 id: 473076 briefTitle: Effect of Home-based Training Program for Kidney Transplant Recipients (HOMETRAIN-KTR) overallStatus: RECRUITING date: 2024-02-07 date: 2027-01-01 date: 2028-01-01 date: 2024-04-23 date: 2024-04-24 name: Oslo University Hospital class: OTHER name: South-Eastern No... |
The goal of this clinical trial is to learn if home-based training works to better physical function in adult kidney transplant recipients. It will also learn about participants preoperative physical function. The main question it aim to answer is |
* Does home-based training improves physical function in kidney transplant recipients. |
* All the participants are assessed to have reduced physical function before the transplantation |
Participants will: |
* follow either a home-based training program or todays standard of physical activity after kidney transplantation |
* the program starts 4 weeks after the transplantation and lasts for 12 weeks. A physiotherapist will help the participants in the beginning. |
* the program consists of both cardio-training, strength-straining and optional activity |
* the training group will be followed up every week by phone. Their activity will be documented via patients logs and heart rate monitor. |
* the effect of the training will be evaluated one year after the transplantation conditions: Kidney Transplant; Complications conditions: Frailty conditions: Physical Disability studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: 2 arms randomized contr... |
<|newrecord|> nctId: NCT06378996 id: S68535 briefTitle: Arrhythmic Mitral Valve Prolapse Detection Using Long-term Ambulatory Rhythm Monitoring acronym: ALARM-PILOT overallStatus: RECRUITING date: 2024-05 date: 2024-09 date: 2024-10 date: 2024-04-23 date: 2024-04-23 name: Universitaire Ziekenhuizen KU Leuven class: OTH... |
Currently, diagnosis is often based on repeated 24-hour Holter monitoring. However, the ventricular arrhythmia burden varies from day-to-day and long-term rhythm monitoring has shown in other pathologies to increase the diagnostic yield with up to 200% (from 22.5% on 24h to 75.3% on 14 days). |
This pilot study aims to study the diagnostic yield of long-term rhythm monitoring in patients with MVP as well as the day-to-day variability of ventricular arrhythmias to facilitate power calculation for a future large-scale prospective registry. conditions: Mitral Valve Prolapse conditions: Ventricular Arrythmia stud... |
* Patients with MVP (not previously known with AMVP) and mild to moderate mitral valve regurgitation |
* Patients with AMVP and mild to moderate mitral valve regurgitation |
* Patients with MVP and severe mitral valve regurgitation scheduled for surgical intervention primaryPurpose: DIAGNOSTIC masking: NONE count: 60 type: ESTIMATED name: 14-day rhythm monitoring measure: Time to arrhythmic mitral valve prolapse detection measure: Number of days with high PVC-burden ≥5% measure: Number of ... |
<|newrecord|> nctId: NCT06378983 id: SYSKY-2023-1149-02 briefTitle: Clinical Trial of Microneedle Radiofrequency Combined With Oral Isotretinoin in Moderate to Severe Acne overallStatus: RECRUITING date: 2022-09-01 date: 2024-06-30 date: 2024-06-30 date: 2024-04-23 date: 2024-04-23 name: Sun Yat-Sen Memorial Hospital o... |
<|newrecord|> nctId: NCT06378970 id: 22-1T/49 briefTitle: Audio Books Effects on Anxiety and Vital Sings overallStatus: COMPLETED date: 2022-04-15 date: 2022-07-15 date: 2022-07-15 date: 2024-04-23 date: 2024-04-23 name: Ege University class: OTHER briefSummary: Objectives: This study aimed to investigate the effect of... |
Research Methodology/Design: It is an experimental-randomised controlled study. Settings: The study was carried out with patients hospitalised in the Chest Diseases Intensive Care Unit of a university hospital and NIMV support. The participants consisted of 60 people, 30 in the intervention group and 30 in the control ... |
Main Outcome Measures: Anxiety levels and vital signs in the intervention group were evaluated before, 15 minutes, 30 minutes and 30 minutes after the end of the intervention. In the control group, only routine care continued and anxiety levels, and vital signs were assessed simultaneously with the intervention group. ... |
<|newrecord|> nctId: NCT06378957 id: IRB00436545 briefTitle: Behavioral Pharmacology of Orally Administered THC and D-limonene overallStatus: NOT_YET_RECRUITING date: 2024-09-01 date: 2027-07-01 date: 2027-12-31 date: 2024-04-23 date: 2024-04-23 name: Johns Hopkins University class: OTHER name: National Institutes of H... |
<|newrecord|> nctId: NCT06378944 id: 61/23 briefTitle: Selective Sentinella Lymph Node Biopsy With Indocyanine Green in Patients With Breast Cancer acronym: INSEAN overallStatus: RECRUITING date: 2024-01-01 date: 2029-01-01 date: 2029-01-01 date: 2024-04-23 date: 2024-04-23 name: Omphis Foundation class: OTHER briefSum... |
<|newrecord|> nctId: NCT06378931 id: 2024HX161 briefTitle: Quality of Life Change in Patients Undergoing Parathyroidectomy With End-stage Renal Failure overallStatus: NOT_YET_RECRUITING date: 2024-04-15 date: 2025-12-30 date: 2025-12-30 date: 2024-04-23 date: 2024-04-23 name: Chunling Jiang class: OTHER briefSummary: T... |
<|newrecord|> nctId: NCT06378918 id: 2023-A02791-44 briefTitle: Comparison of the Effectiveness of the Simple Puncture Compared to the Incision of an Abscess on the piLOnidal Sinus acronym: PILO overallStatus: NOT_YET_RECRUITING date: 2024-06-15 date: 2025-04-15 date: 2027-04-15 date: 2024-04-23 date: 2024-04-23 name: ... |
An alternative has recently been proposed, consisting of a puncture of the abscess, aimed at emptying it under antibiotic coverage. The major advantage of this treatment is that patients no longer need general anesthesia to flatten the abscess. Although this technique is promising, it is currently not the subject of an... |
The research hypothesis is that the two techniques have the same results in terms of recurrence before definitive surgical treatment but that drainage puncture would imply a faster healing time, a lower cost of treatment, a quality of superior support, reduced support time and reduced work stoppage. conditions: Pilonid... |
<|newrecord|> nctId: NCT06378905 id: 141/57 briefTitle: Cukurova Score Validation Study acronym: CUKUROVA overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2026-03 date: 2027-03 date: 2024-04-23 date: 2024-04-23 name: Cukurova University class: OTHER name: Muğla Sıtkı Koçman University name: Sakarya University name... |
The Cukurova score developed in our clinic conceptualizes prioritizing surgical procedures using radiological imaging and diagnostic exploratory laparoscopy to achieve complete cytoreduction in harmony with the patient's clinical and performance status, rather than focusing solely on tumor burden. The score showed high... |
<|newrecord|> nctId: NCT06378892 id: CRO-2023-78 briefTitle: A Study to Evaluate the Combination of Platinum-pemetrexed Based Chemotherapy Plus Lorlatinib in ALK Positive Non-Small Cell Lung Cancer (NSCLC) With Exclusively Extracranial Disease Progression on Lorlatinib acronym: ALK-PPL overallStatus: RECRUITING date: 2... |
<|newrecord|> nctId: NCT06378879 id: 1073/1/3/26 briefTitle: Intermittent Boluses Versus Infusion of Propofol During Gastroscopy overallStatus: NOT_YET_RECRUITING date: 2024-05-06 date: 2025-04-30 date: 2025-07-30 date: 2024-04-23 date: 2024-04-23 name: Al-Balqa Applied University class: OTHER name: Luzmila Hospital br... |
<|newrecord|> nctId: NCT06378866 id: MC230502 id: NCI-2024-02978 type: REGISTRY domain: CTRP (Clinical Trial Reporting Program) id: 23-012176 type: OTHER domain: Mayo Clinic Institutional Review Board id: MC230502 type: OTHER domain: Mayo Clinic in Rochester briefTitle: Stereotactic Body Radiation Therapy Plus Androgen... |
<|newrecord|> nctId: NCT06378853 id: 2023DZKY-049-01 briefTitle: Risk Factors of Postoperative Complications and Survival Rate in Pancreatic Ductal Adenocarcinoma Patients overallStatus: COMPLETED date: 2019-01-01 date: 2023-12-31 date: 2024-02-28 date: 2024-04-23 date: 2024-04-23 name: Jinling Hospital, China class: O... |
<|newrecord|> nctId: NCT06378840 id: KY2021-268-B briefTitle: the Predictive Value of Immune Cell in Locally Advanced Cervical Cancer overallStatus: RECRUITING date: 2022-01-01 date: 2024-12-30 date: 2024-12-30 date: 2024-04-23 date: 2024-04-23 name: RenJi Hospital class: OTHER briefSummary: To explore the predictive v... |
<|newrecord|> nctId: NCT06378827 id: 418-1/2 briefTitle: Intraoperative Dexmedetomidine and Coronary Artery Bypass Graft Surgery overallStatus: RECRUITING date: 2024-04-03 date: 2024-07 date: 2024-10 date: 2024-04-23 date: 2024-04-23 name: University of Novi Sad class: OTHER briefSummary: This is a prospective randomiz... |
<|newrecord|> nctId: NCT06378814 id: IRAS N335444 briefTitle: Outcome of Selective & Nonselective Caries Removal in Permanent Teeth acronym: RCT-SNCR overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2025-04-30 date: 2030-04-30 date: 2024-04-23 date: 2024-04-29 name: King's College London class: OTHER name: Guy'... |
This study will be a randomized controlled trial, with participants divided into two groups: NSCR group and SCR group. Participants of deep caries lesions (reaching more than two-thirds of dentin on periapical radiographs) Both groups will undergo either NSCR or SCR, followed by Partial Pulpotomy (PP) in cases with pul... |
The success rate of the two categories will be assessed using a scale that includes factors such as tooth vitality, caries recurrence, and clinical signs of pulpitis. The scale will be applied at follow-up visits. The trial will be conducted in post-graduate dental clinics at Guy's hospital. |
Deep caries in permanent teeth is a common clinical problem that can lead to pulp exposure and subsequent restorative challenges. The aim of this study is to provide evidence-based guidance for clinicians in managing deep caries lesions, as both NSCR and SCR are commonly used in clinical practice. The results of this s... |
In conclusion, this trial aims to compare the success rate of NSCR and SCR in managing deep caries lesions in permanent teeth, as both methods are commonly used in clinical practice. The results of this study will provide valuable insights into the effectiveness of these two treatment approaches and will help clinician... |
<|newrecord|> nctId: NCT06378801 id: RADX-P-2408 briefTitle: Radicle Relaxation 24: A Study of Health and Wellness Products on Stress and Related Health Outcomes overallStatus: ACTIVE_NOT_RECRUITING date: 2024-02-29 date: 2024-05 date: 2024-08 date: 2024-04-22 date: 2024-04-24 name: Radicle Science class: INDUSTRY brie... |
<|newrecord|> nctId: NCT06378788 id: 2023/211 briefTitle: Muscle Architecture and Muscle Strength in Fibromyalgia overallStatus: RECRUITING date: 2024-02-01 date: 2024-04-30 date: 2024-06-30 date: 2024-04-22 date: 2024-04-25 name: Bezmialem Vakif University class: OTHER briefSummary: The goal of this observational stud... |
* Is there a significant difference in muscle morphology between FMS and controls? |
* Is there a significant difference in muscle strength between FMS and controls? |
* Is there a relationship between muscle thickness and pennation angle of the Quadriceps, gastrocnemius medialis, gastrocnemius lateralis and Tibialis anterior muscles and disease activity, pain and functionality? |
* Is there a correlation between muscle strength in FMS and disease activity, pain and functionality? conditions: Fibromyalgia conditions: Sarcopenia conditions: Muscle Weakness studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: CROSS_SECTIONAL count: 30 type: ESTIMATED name: Demographic informa... |
<|newrecord|> nctId: NCT06378775 id: H23-03334 briefTitle: Robotically-assisted Minimally-invasive Direct Coronary Artery Bypass With Stenting, Randomized Against Coronary Artery Bypass Graft Surgery acronym: ROBOT RCT overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2027-05-01 date: 2028-12-01 date: 2024-04-22... |
<|newrecord|> nctId: NCT06378762 id: 6/2021 briefTitle: Interference of Endurance Training on Strength Development and Neuromuscular Adaptations overallStatus: ACTIVE_NOT_RECRUITING date: 2022-04-01 date: 2024-07-30 date: 2025-07-30 date: 2024-04-22 date: 2024-04-22 name: University of Lisbon class: OTHER name: Fundaçã... |
Does performing CT result in similar improvements in strength and power as doing just strength training? Does performing CT result in similar improvements in cardiorespiratory fitness as doing just endurance training? Are neuromuscular adaptations similar between CT and just strength training? Researchers will compare ... |
<|newrecord|> nctId: NCT06378749 id: 1R43CA275673 type: NIH link: https://reporter.nih.gov/quickSearch/1R43CA275673 briefTitle: Previvors Recharge: A Resilience Program for Cancer Previvors acronym: PreCharge overallStatus: RECRUITING date: 2024-04-11 date: 2024-07-31 date: 2024-07-31 date: 2024-04-22 date: 2024-04-24 ... |
<|newrecord|> nctId: NCT06378736 id: 21-1027 briefTitle: Electroencephalogram Recording in Patients With Systemic Lupus Erythematosus overallStatus: RECRUITING date: 2024-01-22 date: 2026-03-23 date: 2026-03-23 date: 2024-04-22 date: 2024-04-29 name: Northwell Health class: OTHER briefSummary: Patients with systemic lu... |
<|newrecord|> nctId: NCT06378723 id: 2024/01/24 briefTitle: The Relationship Between Upper Extremity Functionality, Trunk Control and Balance in Children With Cerebral Palsy overallStatus: ACTIVE_NOT_RECRUITING date: 2024-02-01 date: 2024-04-15 date: 2024-04-16 date: 2024-04-22 date: 2024-04-23 name: Eastern Mediterran... |
<|newrecord|> nctId: NCT06378710 id: 22-0219 briefTitle: Haemodynamic and Respiratory Effects of a Low Positive End Expiratory Pressure Associated With a Fluid Challenge in Knee-chest Position acronym: OPTIPEP overallStatus: RECRUITING date: 2023-01-20 date: 2025-01-20 date: 2025-01-30 date: 2024-04-22 date: 2024-04-22... |
The knee-pectoral position notably induces an increase in CRF and improves pulmonary ventilation/perfusion ratios. On the other hand, it has been shown that it is accompanied by a reduction in cardiac output of approximately 15% Protective perioperative ventilation including a tidal volume between 6 and 8 ml/kg of theo... |
The combination of the effects of the knee-pectoral position and protective ventilation could be potentiated and be the cause of the sometimes severe arterial hypotension observed in clinical practice. Since this position improves pulmonary ventilation perfusion ratios, the investigators hypothesized that a lower PEEP ... |
The investigators therefore hypothesize that a reduction in PEEP and optimization of vascular filling could help reduce the adverse effects on blood pressure linked to the surgical position. conditions: Surgery studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: OTHER... |
<|newrecord|> nctId: NCT06378697 id: AK111-303 briefTitle: A Phase III Study to Evaluate the Efficacy and Safety of AK111 in Subjects With Active Ankylosing Spondylitis overallStatus: RECRUITING date: 2023-11-10 date: 2025-02-28 date: 2026-04-30 date: 2024-04-22 date: 2024-04-22 name: Akeso class: INDUSTRY briefSummary... |
<|newrecord|> nctId: NCT06378684 id: JW22105 briefTitle: To Evaluate the Safety and Pharmacokinetic Interactions in Healthy Volunteers overallStatus: COMPLETED date: 2023-09-10 date: 2023-12-23 date: 2024-01-13 date: 2024-04-22 date: 2024-04-22 name: JW Pharmaceutical class: INDUSTRY briefSummary: The objective is to e... |
<|newrecord|> nctId: NCT06378671 id: ColdCough briefTitle: Single-center Clinical Study on the Safety and Effect of Bronchoscopic Cryotherapy in Patients With Chronic Cough acronym: ColdCough overallStatus: RECRUITING date: 2024-04 date: 2024-07 date: 2024-09 date: 2024-04-22 date: 2024-04-25 name: Guangzhou Medical Un... |
The goal of this clinical trial is to learn if Cryotherapy treatment works to treat individuals with chronic cough. It will also learn about The safety and effectiveness of the cryotherapy treatment system produced by Ningbo SensCure Biotechnology Co., Ltd.. The main questions it aims to answer are: |
* Does cryotherapy treatment lower the frequency and severity of cough and enhance quality of life? |
* Will there be safety or operational performance issues when using this cryotherapy treatment system? Researchers will compare cryotherapy treatment with no treatment to determine if cryotherapy treatment is effective for treating chronic cough. |
Participants will: |
* Take routine bronchoscopy examination, lavage, and mucosal biopsy ,with/without cryotherapy treatment locally (around the left and right main bronchi, upper trachea, and carina) |
* undergo a screening period of approximately 28 days. Follow-up visits and necessary examinations will be scheduled for the 3rd day after treatment initiation and at weeks 1, 2, 4, 8, and 12 thereafter. |
* Monitor vital signs and clinical manifestations. conditions: Chronic Cough studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: a prospective, single-center, double-blind ,randomized controlled clinical trial primaryPurpose: TREATMENT masking: DOUBLE wh... |
<|newrecord|> nctId: NCT06378658 id: 22253 briefTitle: A Study to Learn About How Food and Esomeprazole Affect the Level of BAY2927088 in the Blood When Taken Together in Healthy Participants overallStatus: RECRUITING date: 2024-03-29 date: 2024-05-20 date: 2024-05-20 date: 2024-04-22 date: 2024-04-22 name: Bayer class... |
Advanced NSCLC refers to a type of lung cancer that has spread from the lungs to nearby tissues or other body parts. People with advanced NSCLC may have changes in certain proteins, like EGFR and HER2, that cause uncontrolled cell growth and increased spread of cancer. |
In this study, participants will be healthy and will not benefit from taking the study treatment, BAY2927088. However, the study will provide information about how to test BAY2927088 in future studies with people who have advanced NSCLC with EGFR or HER2 mutations. |
BAY2927088 is under development for the treatment of advanced NSCLC with EGFR or HER2 mutations. It is expected to work against these changed proteins, which might slow down the spread of cancer. |
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