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The intervention is delivered via the app, which will send daily notifications on physical activity and sedentary behavior, and ask the participants to set their weekly goal (i.e., daily steps). The app will also collect daily steps count and ask the participant to fill in questionnaire on pain once a week. conditions:... |
<|newrecord|> nctId: NCT06385015 id: IRB#23-001257 briefTitle: T-UP: Engaging Vulnerable Students in Diabetes Prevention overallStatus: ACTIVE_NOT_RECRUITING date: 2023-10-04 date: 2024-05 date: 2025-06 date: 2024-04-25 date: 2024-04-26 name: University of California, Los Angeles class: OTHER name: American Diabetes As... |
The specific aims are to: 1) Evaluate the efficacy of adolescents and young adults (AYA)-tailored version of the University of California Diabetes Prevention Program (UC DPP) for mitigating type 2 diabetes risk (i.e., weight change) in a pre/post pilot trial. The investigators hypothesize that the AYA-tailored interven... |
The investigators will randomize participants to the AYA-tailored DPP cohort vs control cohort. Control participants will be offered the opportunity to participate in the AYA-tailored DPP in the following academic year. Participants will be organized into groups within their DPP cohort based on their student status and... |
<|newrecord|> nctId: NCT06385002 id: 2024-0158 briefTitle: Effect of Combined Administration of Sevoflurane and Remimazolam on Emergence overallStatus: NOT_YET_RECRUITING date: 2024-07-01 date: 2025-05-31 date: 2025-05-31 date: 2024-04-25 date: 2024-04-26 name: Pusan National University Yangsan Hospital class: OTHER br... |
<|newrecord|> nctId: NCT06384989 id: MinnesotaHealthSolutions_LL briefTitle: Safety-Enhancing Motor Vehicle Child Safety Seat overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2024-07-01 date: 2024-08-15 date: 2024-04-25 date: 2024-04-25 name: Minnesota HealthSolutions class: INDUSTRY briefSummary: This study ai... |
<|newrecord|> nctId: NCT06384976 id: KYV101-007 briefTitle: A Study of Anti-CD19 CAR T-Cell Therapy, in Subjects With Refractory Primary and Secondary Progressive Multiple Sclerosis overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2027-04 date: 2029-01 date: 2024-04-25 date: 2024-04-25 name: Kyverna Therapeutics c... |
<|newrecord|> nctId: NCT06384963 id: Cer22/02 briefTitle: Respiratory Sinus Arrhythmia Pacing Post-CABG Surgery in Patients With HFrEF acronym: RSA-PACE overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2025-03-01 date: 2025-04-01 date: 2024-04-25 date: 2024-04-25 name: Ceryx Medical Australia class: INDUSTRY na... |
The main questions the trial aims to answer are: |
* Is the new type of pacemaker safe? |
* Does the new type of pacemaker improve how patients' hearts work (also known as cardiac output)? |
Participants will have a range of tests before their operation and during their recovery in hospital while participants have the new type of pacemaker in place, and will be monitored very closely. Participants will also receive a phone call 1 month after their surgery. Researchers will compare the new type of heart pac... |
<|newrecord|> nctId: NCT06384950 id: 2023-11-005A briefTitle: Evaluating the Role of ChatGPT in Educating Patients With Early-stage Hepatocellular Carcinoma overallStatus: RECRUITING date: 2024-03-22 date: 2024-11-29 date: 2025-03-21 date: 2024-04-25 date: 2024-04-25 name: Taipei Veterans General Hospital, Taiwan class... |
The research methodology employs a Randomized Controlled Trial (RCT) design, dividing participants into a control cohort receiving standard patient education routine and an experimental cohort receiving both the AI chatbot and traditional education routine. The comparative analysis of these cohorts will determine the e... |
<|newrecord|> nctId: NCT06384937 id: GCA-PRO-2022-001-01 briefTitle: [Trial of device that is not approved or cleared by the U.S. FDA] overallStatus: WITHHELD date: 2024-04-25 date: 2024-04-25 name: [Redacted] hasResults: False |
<|newrecord|> nctId: NCT06384924 id: SBU-RAMAN-SKINCANCER briefTitle: Raman Spectroscopy and Skin Cancer overallStatus: NOT_YET_RECRUITING date: 2024-04-15 date: 2025-04-30 date: 2025-04-30 date: 2024-04-25 date: 2024-04-25 name: Renee Cattell class: OTHER briefSummary: The goal of this observational study is to find o... |
-Can Raman Spectroscopy help figure out how far a tumor spreads? |
This study will take measurements using laser light from an experimental, handheld probe by lightly touching the skin. conditions: Skin Cancer conditions: Basal Cell Carcinoma conditions: Squamous Cell Carcinoma studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 20 type: ESTIMATED n... |
<|newrecord|> nctId: NCT06384911 id: STUDY00004543 briefTitle: InvesT1D: Promoting Adolescent Investment in Diabetes Care overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2027-08 date: 2028-02 date: 2024-04-25 date: 2024-04-25 name: Seattle Children's Hospital class: OTHER name: Harvard Pilgrim Health Care briefSu... |
Adolescent participants will be randomized to usual care or receive financial incentives for meeting diabetes self-management and clinical outcomes goals during the study. Researchers will compare changes in glucose levels and person-reported outcomes between groups. conditions: Type 1 Diabetes studyType: INTERVENTIONA... |
<|newrecord|> nctId: NCT06384898 id: STUDY00002259 id: UH3AT012413 type: OTHER_GRANT domain: National Center for Complementary and Integrative Health briefTitle: Remote Tai Chi for Knee Osteoarthritis acronym: TAICHIKNEE overallStatus: NOT_YET_RECRUITING date: 2024-09 date: 2026-12 date: 2027-10 date: 2024-04-25 date: ... |
* Does remote Tai Chi improve the extent to which pain interferes with physical, mental, and social activities (PROMIS-Pain Interference at 3 months, primary outcome), as well as knee pain and function (WOMAC subscales) and analgesic use (secondary outcomes) |
* Does remote tai chi decreases healthcare utilization? |
Researchers will compare remote Tai Chi added to routine care to routine care alone to see if remote tai chi works to treat knee osteoarthritis pain. Participants will participate in remotely delivered web-based tai chi sessions, twice a week for 12 weeks, or will continue to receive routine care. Participants will be ... |
<|newrecord|> nctId: NCT06384885 id: 2024-079 briefTitle: Ultrasound Investigation Into Swimming Induced Pulmonary Edema in Open Water Swimming Athletes acronym: SIPE overallStatus: RECRUITING date: 2024-04-15 date: 2025-06-01 date: 2025-12-01 date: 2024-04-25 date: 2024-04-25 name: Rocky Vista University, LLC class: O... |
<|newrecord|> nctId: NCT06384872 id: 230042_RRI_Interv5 briefTitle: Effect of Shoe Cushioning Position and Properties on Running-related Injury Risk acronym: RRI_Interv5 overallStatus: NOT_YET_RECRUITING date: 2024-10-01 date: 2025-09-30 date: 2025-12-31 date: 2024-04-25 date: 2024-04-26 name: Luxembourg Institute of H... |
1. "Extra soft" cushioning materials can reduce injury risk compared to stiffer materials; |
2. Cushioning under the forepart of the shoe also influences injury risk, independently of the cushioning at the rear part; |
3. Effects of cushioning material and position depend on the runner's body mass; |
4. Perception of cushioning is related to both shoe cushioning and injury risk; |
5. Other weight-bearing locomotion activities (i.e., number of steps per day besides running practice) represents an independent risk factor for running-related injury. |
This study consists in a 6-month intervention trial during which leisure-time runners are required to follow their usual training schedule. Before the beginning of the study, the participants will receive a pair of running shoes. The three running shoe models will be exactly the same, except for their foam properties a... |
Participants will first fill out a baseline questionnaire. During the intervention, data on running practice will be downloaded from sports watches and their respective app via Strava. Information on the use of the study shoes will be collected via a weekly questionnaire. Participants will be asked to fill out a weekly... |
Primary hypothesis: |
- Greater shock absorption properties at the rear part of running shoes are associated with a lower injury risk in recreational runners. |
Secondary hypothesis: |
* Greater shock absorption properties under the forepart of the shoe are also associated with lower injury risk in recreational runners. |
* Runners with low body mass experience a lower injury risk in shoes with greater shock absorption properties. |
* Greater perceived cushioning is related to lower injury risk. conditions: Running-related Injury studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: QUADRUPLE maskingDescription: Participants will be stratified according to their sex. Two pre-est... |
<|newrecord|> nctId: NCT06384859 id: Pending briefTitle: Effectiveness of Extracorporeal Shockwave Therapy Combined With Platelet-rich Plasma in the Treatment of Chronic Insertional Achilles Tendinopathy overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2026-05-01 date: 2027-05-01 date: 2024-04-25 date: 2024-04-... |
Does ESWT combined with PRP treatment reduce the symptom and improve functional score after treatment? What medical complication do participants have when receive the treatment? |
Researchers will compare ESWT combined with PRP to ESWT treatment alone to see if ESWT combined with PRP works to treat chronic insertional tendinopathy. |
Participants will: |
* Receive ESWT once a week for 4 weeks then receive PRP injection at a week later or ESWT once a week for 4 weeks |
* Visit the clinic at 6 weeks, 3 months, 6 months and 1 year after treatment for checkups and record functional score conditions: Insertional Achilles Tendinopathy studyType: INTERVENTIONAL phases: PHASE4 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 94 type: ESTIMATE... |
<|newrecord|> nctId: NCT06384846 id: AI ACS briefTitle: AI Algorithms in Prediction of ACS Based on Leukocyte Properties overallStatus: RECRUITING date: 2024-02-01 date: 2026-07-31 date: 2026-12-31 date: 2024-04-25 date: 2024-04-25 name: RobotDreams GmbH class: INDUSTRY briefSummary: The goal of this observational stud... |
- Can AI algorithms based on white blood cell data predict ACS with accuracy comparable to that of high-sensitivity cardiac troponin (hs-cTn)? Researchers will look at how the AI model's predictions stack up against the standard hs-cTn blood tests to see which is more accurate in diagnosing ACS. |
Participants in this study will have already had blood tests as part of their usual care. Their previously collected health information and blood test results will be used to help train and test the AI algorithms. Participants will not undergo any new procedures for the study itself. conditions: Acute Coronary Syndrome... |
<|newrecord|> nctId: NCT06384833 id: Rama briefTitle: Combination of Vitamin C and N-Acetylcysteine to Improve Functional Outcome After Rotator Cuff Repair overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2025-09-01 date: 2026-05-01 date: 2024-04-25 date: 2024-04-25 name: Mahidol University class: OTHER briefSu... |
Do vitamin C and N-acetylcysteine improve the shoulder functional score of participants? Do vitamin C and N-acetylcysteine improve healing of rotator tendon? Researchers will compare vitamin C and N-acetylcysteine to a placebo (a look-alike substance that contains no drug) to see if vitamin C and N-acetylcysteine works... |
Participants will: |
Take vitamin C and N-acetylcysteine or a placebo every day for 45 days. Visit the OPD three times at 2 week, 6 month and 12 month after surgery for checkups and tests. conditions: Rotator Cuff Tears studyType: INTERVENTIONAL phases: PHASE4 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT mas... |
<|newrecord|> nctId: NCT06384820 id: R3767-ONC-2330 id: 2023-510514-38-00 type: REGISTRY domain: EU CT Number briefTitle: Study of Cemiplimab Alone or in Combination With Fianlimab and/or Other Experimental Agents in Adult Participants With Peri-operative Stage III/IV Cutaneous Squamous Cell Carcinoma (CSCC) overallSta... |
The aim of the study is to see if cemiplimab or cemiplimab in combination with fianlimab can eliminate or reduce the number of living cancer cells in tumor(s) if taken before surgery. |
The study is looking at several other research questions, including: |
* Whether taking cemiplimab or cemiplimab in combination with fianlimab before surgery may make it possible to have a less extensive surgery or a different treatment plan after surgery |
* Whether taking cemiplimab or cemiplimab in combination with fianlimab before surgery may make the cancer less likely to come back after surgery |
* What side effects may happen from taking the cemiplimab or cemiplimab in combination with fianlimab |
* How much of the cemiplimab or cemiplimab in combination with fianlimab is in the blood at different times |
* Whether the body makes antibodies against the study drug(s) (which could make the drug(s) less effective or could lead to side effects) conditions: Cutaneous Squamous Cell Carcinoma studyType: INTERVENTIONAL phases: PHASE2 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE coun... |
<|newrecord|> nctId: NCT06384807 id: BHV1510-101 (PBI-410-101) briefTitle: A Phase 1/2 Study of PBI-410 in Advanced Solid Tumors overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2028-02 date: 2028-02 date: 2024-04-25 date: 2024-04-25 name: Pyramid Biosciences class: INDUSTRY briefSummary: This is a Phase 1/2, firs... |
<|newrecord|> nctId: NCT06384794 id: 2211-VLC-157-MD briefTitle: Study of the ZyMōt Sperm Selection Method and Its Effect on Embryo Ploidy. acronym: ZYMOT2 overallStatus: RECRUITING date: 2023-06-29 date: 2025-07-01 date: 2026-12-31 date: 2024-04-25 date: 2024-04-29 name: Instituto Valenciano de Infertilidad, IVI VALEN... |
<|newrecord|> nctId: NCT06384781 id: 2130836 id: R61DA059892-01 type: NIH link: https://reporter.nih.gov/quickSearch/R61DA059892-01 briefTitle: Development, Refinement, and Validation of a Peer Support Specialist Checklist for Individuals With Opioid Use Disorder / STAMPS: South Carolina Buprenorphine Treatment Initiat... |
<|newrecord|> nctId: NCT06384768 id: EBIst id: 1919B012104428 type: OTHER_GRANT domain: TUBITAK briefTitle: Video Training on Pre-Pregnancy Fear of Birth in Male Partners overallStatus: COMPLETED date: 2022-02-01 date: 2022-05-01 date: 2022-08-30 date: 2024-04-25 date: 2024-04-26 name: Istanbul University - Cerrahpasa ... |
<|newrecord|> nctId: NCT06384755 id: 645788 id: 2022_HE2_409659 type: OTHER_GRANT domain: The Dam Foundation id: 645788 type: OTHER domain: Regional Ethics Committee (REK), South-East Norway briefTitle: Honest Open Proud for Psychotic and Bipolar Disorder in Norway acronym: HOP-NOR overallStatus: RECRUITING date: 2024-... |
<|newrecord|> nctId: NCT06384742 id: K23HL157698 type: NIH link: https://reporter.nih.gov/quickSearch/K23HL157698 briefTitle: Shift Worker Intervention for Sleep Health acronym: SWISH overallStatus: NOT_YET_RECRUITING date: 2024-09 date: 2026-09 date: 2027-03 date: 2024-04-25 date: 2024-04-25 name: Oregon State Univers... |
<|newrecord|> nctId: NCT06384729 id: 123 briefTitle: Effectiveness of the EXOPULSE Mollii Ⓡ Suit in Patients With Multiple Sclerosis overallStatus: RECRUITING date: 2024-04-01 date: 2024-05-01 date: 2024-09-01 date: 2024-04-25 date: 2024-04-25 name: Universidad Europea de Madrid class: OTHER briefSummary: Abstract: |
Background: |
Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system with unknown etiology, causing a variety of symptoms including impaired balance, coordination, and walking difficulties. The Exopulse Mollii Ⓡ suit is an innovative approach for non-invasive, self-administered electric... |
Objective: |
To determine the effectiveness of the Exopulse Mollii Ⓡ suit in improving motor control in patients with MS. |
Methods: |
A randomized, double-blind clinical trial will be conducted, recruiting patients diagnosed with MS , aged 18 or above, with a Functional Ambulation Category (FAC) score between 2 and 4. Patients will be randomly assigned to two groups receiving either inactive or active Exopulse Mollii Ⓡ treatment for 60 minutes, three... |
Results: |
Data on age, sex, weight, and MS-related factors will be collected at baseline. Primary outcomes include changes in pain, balance, and gait speed, while secondary outcomes encompass risk of falls, perception of walking difficulties, and quality of life. Analysis will compare mean differences between groups using approp... |
Conclusion: |
This study aims to evaluate the efficacy of the Exopulse Mollii Ⓡ suit in enhancing motor function in MS patients. Findings may contribute to the development of novel therapeutic strategies for managing MS-related symptoms and improving patients' quality of life. conditions: Multiple Sclerosis studyType: INTERVENTIONAL... |
<|newrecord|> nctId: NCT06384716 id: CEB briefTitle: Evaluation of the Influence of a Core Muscle Control-Based Rehabilitation Program Patients With Multiple Sclerosis overallStatus: RECRUITING date: 2024-02-19 date: 2024-07-01 date: 2024-09-01 date: 2024-04-25 date: 2024-04-25 name: Universidad Europea de Madrid class... |
<|newrecord|> nctId: NCT06384703 id: 201518015 briefTitle: The Relationship Between Microbiota and Coronary Ectasia overallStatus: COMPLETED date: 2020-11-03 date: 2021-04-25 date: 2021-06-18 date: 2024-04-25 date: 2024-04-25 name: Konya Beyhekim Training and Research Hospital class: OTHER_GOV name: Necmettin Erbakan U... |
<|newrecord|> nctId: NCT06384690 id: 4331899 briefTitle: Generating Health Evidence From Dietary Supplementation With a Micro-vegetable Blend overallStatus: RECRUITING date: 2024-02-01 date: 2024-11-30 date: 2025-08-31 date: 2024-04-25 date: 2024-04-25 name: University of Exeter class: OTHER name: Advanced Growers Limi... |
<|newrecord|> nctId: NCT06384677 id: 03.03.2023/371 briefTitle: Comparison of Postoperative Analgesia Methods in Patients Undergoing Major Intraabdominal Surgery overallStatus: COMPLETED date: 2023-04-20 date: 2024-02-01 date: 2024-02-01 date: 2024-04-25 date: 2024-04-25 name: Marmara University class: OTHER briefSumma... |
<|newrecord|> nctId: NCT06384664 id: HUM00241242 briefTitle: Cryoablation Effects on Acute and Chronic Pain After Thoracotomy and Thoracoscopy overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2027-04 date: 2028-04 date: 2024-04-25 date: 2024-04-25 name: University of Michigan class: OTHER name: AtriCure, Inc. brie... |
<|newrecord|> nctId: NCT06384651 id: PRO00037789 briefTitle: Intraosseous vs. Intravenous Vancomycin Administration in Total Ankle Arthroplasty acronym: IOTAA overallStatus: RECRUITING date: 2023-12-13 date: 2027-04 date: 2027-12 date: 2024-04-25 date: 2024-04-25 name: The Methodist Hospital Research Institute class: O... |
Primary Objective: Comparable levels of vancomycin will be found in bone, soft tissue, and systemic samples between patient groups. |
Secondary Objective: Compare 30 day and 90 day post-operative complication rates (infection) between the control (standard IV administration of vancomycin) vs the interventional group (intraosseous administration of vancomycin). The investigators hypothesize that there will be no difference in complication (infection) ... |
<|newrecord|> nctId: NCT06384638 id: coconut periodontitis briefTitle: Coconut Oil in Treatment of Periodontitis overallStatus: COMPLETED date: 2022-02-15 date: 2024-01-16 date: 2024-02-09 date: 2024-04-25 date: 2024-04-25 name: Misr University for Science and Technology class: OTHER briefSummary: Virgin Coconut Oil (V... |
<|newrecord|> nctId: NCT06384625 id: 361378 briefTitle: Air Pollution Intervention for Cardiovascular Patients overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2025-02-01 date: 2025-02-01 date: 2024-04-25 date: 2024-04-25 name: University of Montana class: OTHER name: Providence Heart Institute briefSummary: Th... |
<|newrecord|> nctId: NCT06384612 id: Adnan Menderes U briefTitle: The Effect Of The Use Of Pocket Cards In An Undergraduate Nursıng overallStatus: COMPLETED date: 2021-09-13 date: 2022-05-22 date: 2023-07-13 date: 2024-04-25 date: 2024-04-25 name: Aydin Adnan Menderes University class: OTHER briefSummary: The aim of th... |
1. H01. There is no difference between the self-efficacy perception scores of the students in the group who use pocket cards in the care of children with special needs course and the students in the group who do not use pocket cards. |
2. H02. There is no significant difference between the course success scores of the students in the group who use pocket cards in the care of children with special needs course and the students in the group who do not use pocket cards. conditions: Student conditions: Self Efficacy studyType: INTERVENTIONAL phases: NA a... |
<|newrecord|> nctId: NCT06384599 id: CS-190 briefTitle: VT Cryoablation System Post-Market Clinical Follow-up (PMCF) Study overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2026-06-01 date: 2026-06-01 date: 2024-04-25 date: 2024-04-25 name: Adagio Medical class: INDUSTRY briefSummary: The PMCF is a prospective, ... |
<|newrecord|> nctId: NCT06384586 id: CD J8855 briefTitle: Investigation of Dietary Supplement Liquid Shot Products on Mental Energy, Cognition (Acuity),and Mood overallStatus: COMPLETED date: 2022-11-17 date: 2022-12-22 date: 2022-12-22 date: 2024-04-25 date: 2024-04-25 name: The Water Street Collective class: INDUSTRY... |
<|newrecord|> nctId: NCT06384573 id: DIAN-TU-003 id: The Alzheimer's Association type: OTHER_GRANT domain: DIAN-TU-OLE-21-725093 briefTitle: DIAN-TU Amyloid Removal Trial (ART) in Dominantly Inherited Alzheimer's Disease acronym: DIAN-TU overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2029-11 date: 2029-11 date: ... |
<|newrecord|> nctId: NCT06384560 id: 2023-508707-20-00 briefTitle: Neoadjuvant Triple Treatment for Borderline Resectable Pancreatic Cancer (PREOPANC-5) acronym: PREOPANC-5 overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2028-03 date: 2028-03 date: 2024-04-25 date: 2024-04-25 name: Amsterdam UMC, location VUmc cl... |
<|newrecord|> nctId: NCT06384547 id: VRDN-001-303 briefTitle: A Randomized, Active Controlled, Safety and Tolerability Study of VRDN-001 in Participants With Thyroid Eye Disease (TED) overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2025-05 date: 2026-01 date: 2024-04-25 date: 2024-04-25 name: Viridian Therapeutic... |
<|newrecord|> nctId: NCT06384534 id: PVD_6MWD_SOT briefTitle: Exercise Performance on Ambient Air vs. Low-Flow Oxygen Therapy in Pulmonary Vascular Disease (PVD) overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2025-05 date: 2025-11 date: 2024-04-25 date: 2024-04-25 name: University of Zurich class: OTHER briefSum... |
<|newrecord|> nctId: NCT06384521 id: STUDY00000500 briefTitle: Lifestyle MIND- Feasibility for Randomized Wait-list Control Trial acronym: MIND overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2025-04 date: 2025-05 date: 2024-04-25 date: 2024-04-25 name: The University of Texas Health Science Center at San Antonio... |
* Does Lifestyle MIND improve diabetes control among people with SMI? |
* Will the effect of Lifestyle MIND be sustained 10 weeks after program completion? |
* From the provider's perspective, what are the barriers of achieving optimal diabetes treatment outcomes for patients with SMI? |
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