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Methods: The retrospective cohort study was designed to collect data on Thai heart failure with reduced ejection fraction patients at Out-patient Clinic, Trat Hospital and Phrapokklao Hospital from January 2016 to December 2020. Thirteen factors were analyzed to determine their association with the sub-target group. co... |
<|newrecord|> nctId: NCT06382558 id: s68470 id: C2M/23/060 type: OTHER_GRANT domain: KU Leuven briefTitle: Validity and Reliability of Sensorimotor Processing Paradigm overallStatus: RECRUITING date: 2024-04-10 date: 2024-12-31 date: 2024-12-31 date: 2024-04-24 date: 2024-04-24 name: KU Leuven class: OTHER briefSummary... |
<|newrecord|> nctId: NCT06382545 id: Approval number 36.3.22 briefTitle: Post-instrumentation Pain After Use of the Fanta and M3 Pro Gold Systems overallStatus: COMPLETED date: 2021-11-01 date: 2022-06-30 date: 2022-07-30 date: 2024-04-24 date: 2024-04-24 name: Ahram Canadian University class: OTHER briefSummary: Compa... |
<|newrecord|> nctId: NCT06382532 id: AFMMUChina_NSRT briefTitle: Diagnosis of Depressive Disorder Malinger Using the Niacin Skin Response Test (NSRT) overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2026-05-01 date: 2026-05-01 date: 2024-04-24 date: 2024-04-24 name: Air Force Military Medical University, China ... |
<|newrecord|> nctId: NCT06382519 id: Thal in VEOIBD briefTitle: Thalidomide Therapy for VEOIBD overallStatus: NOT_YET_RECRUITING date: 2024-05-15 date: 2025-12-31 date: 2026-12-31 date: 2024-04-24 date: 2024-04-24 name: Children's Hospital of Fudan University class: OTHER briefSummary: This is a single center, observat... |
<|newrecord|> nctId: NCT06382506 id: 2024/138 briefTitle: The Effect of Hazelnut Flour on Blood Glucose acronym: Hazelnut overallStatus: COMPLETED date: 2024-03-21 date: 2024-04-21 date: 2024-04-21 date: 2024-04-24 date: 2024-04-24 name: Ege University class: OTHER briefSummary: One of the factors affecting human healt... |
<|newrecord|> nctId: NCT06382493 id: B-2011-648-005 briefTitle: Tegoprazan-containing Sequential for H. Pylori overallStatus: RECRUITING date: 2021-02-01 date: 2024-12-12 date: 2024-12-12 date: 2024-04-24 date: 2024-04-24 name: Seoul National University Bundang Hospital class: OTHER briefSummary: As H. pylori eradicati... |
<|newrecord|> nctId: NCT06382480 id: 90/2023 briefTitle: PROTeIn-rich Meals to Control Glucose acronym: PROTIME overallStatus: RECRUITING date: 2024-04-12 date: 2026-12-31 date: 2027-02-28 date: 2024-04-24 date: 2024-04-24 name: German Institute of Human Nutrition class: OTHER name: Charite University, Berlin, Germany ... |
<|newrecord|> nctId: NCT06382467 id: 2401-136-016 briefTitle: Comparison of Remimazolam and Propofol Combination vs. Propofol in IOM overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2025-05 date: 2025-06 date: 2024-04-24 date: 2024-04-24 name: Chung-Ang University Gwangmyeong Hospital class: OTHER briefSummary: Th... |
<|newrecord|> nctId: NCT06382454 id: E2-23-5921 briefTitle: Upper Extremity Robot-Assisted Therapy in Stroke Patients overallStatus: NOT_YET_RECRUITING date: 2024-04-22 date: 2025-03-30 date: 2025-03-30 date: 2024-04-24 date: 2024-04-24 name: Hacettepe University class: OTHER name: Interact Medical Technologies Inc. br... |
<|newrecord|> nctId: NCT06382441 id: KC/KE-23-0122/ER-4 briefTitle: A Tele-exercise Program for Breast Cancer Survivors overallStatus: ACTIVE_NOT_RECRUITING date: 2023-11-01 date: 2024-05-31 date: 2024-05-31 date: 2024-04-24 date: 2024-04-24 name: Hong Kong Baptist University class: OTHER briefSummary: The research pro... |
Breast cancer is identified as the most prevalent cancer among women globally and in Hong Kong. The document states that adjuvant therapies post-surgery, such as radiation and chemotherapy, can have both short-term and long-term side effects, which may affect the survivors' physical and mental health. |
The study is based on evidence that physical activity levels often decrease after a breast cancer diagnosis and that exercise can mitigate the side effects of treatment, improving health and quality of life. The pilot aims to test the acceptability and feasibility of a 12-week tele-exercise program that combines psycho... |
The study will enrol 24 patients, randomly assigning them to an intervention group or an active control group. The intervention group will receive 12 online training sessions plus 4 psychological counselling sessions, whereas the control group will receive educational essays on exercise and health. |
The training sessions for the intervention group will include various exercises with increasing intensity and duration over the 4 weeks, monitored by a pulse oximeter to ensure exercises are done at the appropriate heart rate. The sessions will be led by qualified coaches, with Dr. Gao overseeing quality control. condi... |
<|newrecord|> nctId: NCT06382428 id: T-DAYICAN-002 briefTitle: The Effects of Pelvic Floor Muscle Training Applied With the Telerehabilitation Method in the Postpartum Period overallStatus: COMPLETED date: 2022-12-30 date: 2023-11-30 date: 2024-01-30 date: 2024-04-24 date: 2024-04-24 name: Izmir Tinaztepe University cl... |
<|newrecord|> nctId: NCT06382415 id: VINCat_PDO_2 briefTitle: Organ/Space Surgical Site Infection and Recurrence and Survival in Rectal Cancer Surgery acronym: VINCat_PDO_2 overallStatus: COMPLETED date: 2011-01-01 date: 2016-12-31 date: 2024-03-31 date: 2024-04-24 date: 2024-04-24 name: Hospital de Granollers class: O... |
<|newrecord|> nctId: NCT06382402 id: 23.0924 briefTitle: A CCTA Guided Management Strategy Versus a Standard of Care Strategy in Type 2 NSTEMI overallStatus: NOT_YET_RECRUITING date: 2024-04-30 date: 2026-04-30 date: 2026-04-30 date: 2024-04-24 date: 2024-04-25 name: University of Louisville class: OTHER briefSummary: ... |
<|newrecord|> nctId: NCT06382389 id: DR220204 id: 2023-504691-18-00 type: CTIS briefTitle: Efficacy of EMONO as an add-on Therapy to Conventional Antidepressants for the Treatment of Depressive Symptoms in Nursing-home Residents With Neurocognitive Disorders: a Randomized Controlled Trial- acronym: PROTO-EHPAD overallS... |
Recent evidence suggests that nitrous oxide (N2O) in its most commonly used packaging of EMONO (Equimolar Mixture of Oxygen and Nitrous Oxide) has rapid antidepressant properties and a good safety profile. However, no study has investigating the antidepressant effect of EMONO in a population of depressed older adults w... |
The principal goal of the PROTO-EHPAD study is to compare the changes in depressive symptoms in such individuals in a randomized controlled trial with a follow up period of 8 weeks, with a dosage escalation procedure. conditions: Depression conditions: Neurocognitive Disorders studyType: INTERVENTIONAL phases: PHASE2 a... |
<|newrecord|> nctId: NCT06382376 id: 2024-60 briefTitle: The Effect of Analgesia Methods Applied in Gynecological Cancer Surgeries on Postoperative Analgesia overallStatus: COMPLETED date: 2023-06-01 date: 2023-12-01 date: 2024-03-01 date: 2024-04-24 date: 2024-04-26 name: Bakirkoy Dr. Sadi Konuk Research and Training ... |
The key question(s) it aims to answer are: |
\[Is intrathecal morphine more effective in postoperative analgesia?\] Patients who underwent gynecological cancer surgery were examined retrospectively. The investigators evaluated the effect of intrathecal morphine and four-quadrant transversus abdominis plane block applied for postoperative analgesia on pain scores ... |
<|newrecord|> nctId: NCT06382363 id: UW21-363 briefTitle: Improving T2DM Detection Using Spot cHbA1c Test - a Cluster RCT acronym: DM-REACH overallStatus: RECRUITING date: 2022-06-11 date: 2024-09-30 date: 2024-09-30 date: 2024-04-24 date: 2024-04-24 name: The University of Hong Kong class: OTHER name: Hospital Authori... |
Design: Pragmatic cluster randomized controlled trial. |
Setting: 8 public primary care clinics in Hong Kong. |
Participants: A minimum of 776 patients (97 per clinic) who have ≥1 risk factor for T2DM, but no known diagnosis of DM or DM screening in the past 12 months. |
Intervention: Participants at intervention clinics (n=4) will be offered free POC-cHbA1c testing on-site, immediately informed of test results and DM risk, and scheduled for confirmatory oral glucose tolerance test (OGTT) if screened positive (i.e. HbA1c≥5.6%). Participants at control clinics will be offered free vHbA1... |
Main outcome measures: Primary outcomes are uptake rate of POC-cHbA1c versus vHba1c testing, and difference in proportion of T2DM detected between intervention and control groups. |
Secondary outcomes include number-needed-to-screen to detect one more T2DM case. |
Data analysis: Participants' characteristics and test uptake rates will be summarized by descriptive statistics. Difference in the proportion of T2DM detected between groups will be compared using Chi-squared test. Number-needed-to screen to identify one additional patient with DM will be calculated. |
Expected results: A greater proportion of T2DM patients will be detected by POC-cHbA1c than vHbA1c due to a higher screening test uptake rate among the studied population. conditions: Diabetes Mellitus conditions: Pre-diabetes studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL prima... |
<|newrecord|> nctId: NCT06382350 id: KHL-002-2024 briefTitle: Glycemic Excursions in Patients With Type 1 Diabetes Mellitus Using Closed-loop Systems acronym: SAFEDRIVE overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2025-09 date: 2026-05 date: 2024-04-24 date: 2024-04-24 name: University Hospital, Motol class: O... |
<|newrecord|> nctId: NCT06382337 id: A03010240S briefTitle: Immediate Dental Implants in The Upper Anterior Region overallStatus: NOT_YET_RECRUITING date: 2024-04-21 date: 2025-03 date: 2025-04 date: 2024-04-24 date: 2024-04-24 name: Mansoura University class: OTHER briefSummary: The aim of the study will be to evaluat... |
<|newrecord|> nctId: NCT06382324 id: 202301280B0 briefTitle: The Psychological Impact of Mindfulness Intervention to Anterior Cruciate Ligament Reconstruction overallStatus: RECRUITING date: 2024-04 date: 2025-06 date: 2025-12 date: 2024-04-24 date: 2024-04-24 name: Chang Gung Memorial Hospital class: OTHER briefSummar... |
Mindfulness intervention is a psychological approach that involves non-judgmental awareness and focus on moment to moment. Mindfulness practice is known to reduce stress in athletes, promote recovery, enhance athletic performance, and improve sleep quality. Good sleep quality contributes to emotional stability and phys... |
Therefore, investigators hypothesize that integrating mindfulness practice into daytime napping may lead to improved spirit upon waking, reduce sleep inertia, and over time, potentially increase the rate of return to sports after ACL reconstruction. conditions: Anterior Cruciate Ligament (Acl) Reconstruction studyType:... |
* Mindfulness napping group: listening to a record of mindfulness meditation practice for 40 minutes. |
* Control group: listening to light music for 40 minutes. primaryPurpose: TREATMENT masking: SINGLE maskingDescription: The outcome assessor of polysomnography did not know the data belongs which group whoMasked: OUTCOMES_ASSESSOR count: 80 type: ESTIMATED name: mindfulness practice of body scan name: listening to ligh... |
<|newrecord|> nctId: NCT06382311 id: 221824 briefTitle: A Study to Find and Confirm the Dose and Assess Safety, Reactogenicity and Immune Response of a Vaccine Against Pandemic H5N1 Influenza Virus in Healthy Younger and Older Adults overallStatus: RECRUITING date: 2024-04-18 date: 2024-08-21 date: 2025-05-21 date: 202... |
<|newrecord|> nctId: NCT06382298 id: PROJECT00009332 briefTitle: Cottonseed Oil Versus Matched PUFA Effects overallStatus: NOT_YET_RECRUITING date: 2024-08 date: 2026-12 date: 2028-05 date: 2024-04-24 date: 2024-04-26 name: University of Georgia class: OTHER name: United States Department of Agriculture (USDA) briefSum... |
The specific aims are: |
* Examine the impact of CSO vs. PUFA on fasting and postprandial lipids. |
* Examine the impact of CSO on other markers of chronic disease risk. |
Participants will be asked to: |
* Consume provided meal replacement shakes daily for 28-days. |
* Attend three weekly short visits for fasting blood draws, body measurements, and collect the next week of study materials, |
* Attend two longer (5.5h) testing visits which include eating a standardized breakfast meal and having blood drawn periodically before and after breakfast. |
Researchers will compare CSO vs. PUFA and control groups (receiving a mixture of oils) to see if CSO is unique in imparting health benefits when compared with similar matched oil diets. conditions: Dyslipidemia conditions: Overweight and Obesity conditions: Nutrition, Healthy studyType: INTERVENTIONAL phases: NA alloca... |
<|newrecord|> nctId: NCT06382285 id: 0206-22-ASF briefTitle: The Effect of a Prolonged Peripheral Nerve Block on the Level of Pain After a Knee Replacement overallStatus: NOT_YET_RECRUITING date: 2024-10-30 date: 2025-10-30 date: 2026-01-31 date: 2024-04-24 date: 2024-04-24 name: Assaf-Harofeh Medical Center class: OTH... |
<|newrecord|> nctId: NCT06382272 id: IRB23-2027 briefTitle: [Trial of device that is not approved or cleared by the U.S. FDA] overallStatus: WITHHELD date: 2024-04-24 date: 2024-04-24 name: [Redacted] hasResults: False |
<|newrecord|> nctId: NCT06382259 id: H24-Acute-Movement-Breaks briefTitle: The Acute Effect of Movement Breaks on Glycemic Responses in Individuals With Type 2 Diabetes overallStatus: NOT_YET_RECRUITING date: 2024-04-19 date: 2025-07-15 date: 2025-07-15 date: 2024-04-24 date: 2024-04-24 name: University of British Colu... |
<|newrecord|> nctId: NCT06382246 id: H24-Acute-ExSnacks briefTitle: The Acute Effect of "Exercise Snacks" on Glycemic Responses in Individuals With Type 2 Diabetes overallStatus: NOT_YET_RECRUITING date: 2024-04-19 date: 2025-07-15 date: 2025-07-15 date: 2024-04-24 date: 2024-04-24 name: University of British Columbia ... |
<|newrecord|> nctId: NCT06382233 id: PRO-FUTURE project briefTitle: The PRO-FUTURE Project acronym: PRO-FUTURE overallStatus: RECRUITING date: 2024-01-30 date: 2026-01-30 date: 2028-01-30 date: 2024-04-24 date: 2024-04-24 name: University of Campania "Luigi Vanvitelli" class: OTHER name: University of Milan name: A.O.R... |
* Are Urinary single-cell and extracellular vesicles (EVs) screening useful to stage the intrarenal injury and repair processes in UPJO babies? |
* Do babies with unilateral UPJO have a whole blood gene expression profiling (WBGEP) allowing an accurate unilateral UPJO diagnosis? conditions: Ureteropelvic Junction Obstruction conditions: Chronic Kidney Diseases studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: PROSPECTIVE count: 85 type: ... |
<|newrecord|> nctId: NCT06382220 id: R550 briefTitle: Low Dose Bupivacaine Versus Prilocaine Regarding Hemodynamic Stability and Safety in Geriatrics overallStatus: RECRUITING date: 2024-04-23 date: 2024-07-25 date: 2024-08-15 date: 2024-04-24 date: 2024-04-25 name: Fayoum University Hospital class: OTHER briefSummary:... |
Spinal anesthesia can cause disastrous hemodynamical changes in the form of hypotension and bradycardia in elderly patients due to limited physiological reserve and presence of systemic illness . The degree of hypotension is proportional to the extent of sympathetic blockade. thus unilateral Spinal anesthesia described... |
Bupivacaine has been used in spinal anaesthesia in orthodecic surgeries . It provides a short motor block onset time with a long motor block duration . If bupivacaine is used, the main disadvantage is the significant inter-individual variability with clinically significant differences in onset time, dermatomal spread a... |
The aim of this study |
To compare between Unilateral low dose spinal anesthesia using bupivacaine versus prilocaine regarding hemodynamical stability and safety in below knee orthopedic surgeries in elderly people. conditions: Recruitment studyType: INTERVENTIONAL phases: PHASE1 phases: PHASE2 allocation: RANDOMIZED interventionModel: PARALL... |
<|newrecord|> nctId: NCT06382207 id: HM20029298 briefTitle: Effectiveness of the Eko Digital Stethoscope in Capturing Infant ECGs overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2024-12 date: 2024-12 date: 2024-04-24 date: 2024-04-24 name: Virginia Commonwealth University class: OTHER name: Eko Devices, Inc. brie... |
<|newrecord|> nctId: NCT06382194 id: STUDY00014522 id: 1R21AG076362-01 type: NIH link: https://reporter.nih.gov/quickSearch/1R21AG076362-01 briefTitle: Decision Making Tool for Firearm Storage overallStatus: RECRUITING date: 2024-04-01 date: 2024-06-30 date: 2024-07-31 date: 2024-04-24 date: 2024-04-24 name: University... |
<|newrecord|> nctId: NCT06382181 id: 2023- ENFPOD-2621979 id: Silvia Corchón Arreche type: OTHER domain: University of Valencia id: Omar Cauli type: OTHER domain: University of Valencia briefTitle: A Multimodal Intervention for Community-dwelling Individuals With Unwanted Loneliness overallStatus: COMPLETED date: 2023-... |
<|newrecord|> nctId: NCT06382168 id: D19-11186 briefTitle: Phase I/II Study of DFP-10917 in Combination With Venetoclax in Relapsed or Refractory Acute Myeloid Leukemia overallStatus: NOT_YET_RECRUITING date: 2024-05-31 date: 2025-03-31 date: 2025-06-30 date: 2024-04-24 date: 2024-04-24 name: Delta-Fly Pharma, Inc. cla... |
<|newrecord|> nctId: NCT06382155 id: 111-210 briefTitle: A Phase 2 Study of Vosoritide in Children With Idiopathic Short Stature overallStatus: NOT_YET_RECRUITING date: 2024-09 date: 2026-06 date: 2036-12 date: 2024-04-24 date: 2024-04-24 name: BioMarin Pharmaceutical class: INDUSTRY briefSummary: The purpose of this s... |
<|newrecord|> nctId: NCT06382142 id: BL-B01D1-307 briefTitle: A Study Comparing BL-B01D1 With Chemotherapy of Physician's Choice in Patients With Unresectable Locally Advanced or Metastatic Triple-Negative Breast Cancer overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2026-05 date: 2026-05 date: 2024-04-24 date: 2... |
<|newrecord|> nctId: NCT06382129 id: BL-B01D1-302 briefTitle: A Study Comparing BL-B01D1 With Docetaxel in Patients With Unresectable Locally Advanced or Metastatic EGFR Wild-type Non-small Cell Lung Cancer overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2026-05 date: 2026-05 date: 2024-04-24 date: 2024-04-24 nam... |
<|newrecord|> nctId: NCT06382116 id: BL-B01D1-301 briefTitle: A Study Comparing BL-B01D1 With Platinum Based Chemotherapy in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2026-05 date: 2026-05 date: 2024-04-24 date: 2024-04-24 name: Sichuan... |
<|newrecord|> nctId: NCT06382103 id: B2024-108R briefTitle: Biomarkers and Molecular Mechanism Study of Hepatocellular Carcinoma After Radical Resection and Conversion Therapy overallStatus: NOT_YET_RECRUITING date: 2024-04-20 date: 2025-05-20 date: 2026-05-20 date: 2024-04-24 date: 2024-04-24 name: Shanghai Zhongshan ... |
<|newrecord|> nctId: NCT06382090 id: PamukkaleU-SBE-BB-01 briefTitle: Premenstrual Syndrome and Laughter Yoga overallStatus: NOT_YET_RECRUITING date: 2024-04-26 date: 2024-05-24 date: 2025-05-24 date: 2024-04-24 date: 2024-04-24 name: Pamukkale University class: OTHER briefSummary: In addition to physical and emotional... |
<|newrecord|> nctId: NCT06382077 id: CPSP5502 briefTitle: Chronic Post Surgical Pain-Cardiac acronym: CPSP-Cardiac overallStatus: NOT_YET_RECRUITING date: 2024-04-25 date: 2025-04-25 date: 2025-10-25 date: 2024-04-24 date: 2024-04-24 name: Ondokuz Mayıs University class: OTHER briefSummary: The CPSP-Cardiac is a large,... |
<|newrecord|> nctId: NCT06382064 id: 2024H0089 briefTitle: Evaluation of Wear Experience With One Week Reusable Contact Lenses in Habitual Two Week Reusable Lens Wearers overallStatus: ACTIVE_NOT_RECRUITING date: 2024-04-16 date: 2024-09 date: 2025-05 date: 2024-04-24 date: 2024-04-24 name: Ohio State University class:... |
<|newrecord|> nctId: NCT06382051 id: CAIN457ACA06 briefTitle: Modifying PEST for Psoriatic Arthritis Screening acronym: ScreenX overallStatus: NOT_YET_RECRUITING date: 2024-06-28 date: 2025-04-30 date: 2025-04-30 date: 2024-04-24 date: 2024-04-24 name: Novartis Pharmaceuticals class: INDUSTRY briefSummary: The purpose ... |
Patients will be enrolled in the study for up to 66 days and will be asked to fill-out a PsA screening questionnaire at their first dermatologist visit. Patients screening positive for PsA will have a second visit with a rheumatologist where a full PsA diagnosis assessment will be performed. A remote 'end of study' (EO... |
<|newrecord|> nctId: NCT06382038 id: HZKY-PJ-2024-19 briefTitle: Smart Technology Facilitated Patient-centered Care for Patients With Pulmonary Thromboembolism acronym: SmaPE overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2026-10-31 date: 2026-10-31 date: 2024-04-24 date: 2024-04-24 name: Navy General Hospita... |
The objective of this study is to evaluate the impact of mobile venous thromboembolism application (mVTEA) based patient-centered management of pulmonary thromboembolism (PTE) on the long-term outcome of PTE patients, in order to enhance clinical practice and establish a foundation of evidence for managing patients wit... |
<|newrecord|> nctId: NCT06382025 id: Alkinstorybook briefTitle: Preoperative Information With Storybook for Pediatric Anesthesia overallStatus: COMPLETED date: 2018-03-09 date: 2020-02-20 date: 2020-05-29 date: 2024-04-24 date: 2024-04-24 name: Trakya University class: OTHER briefSummary: Impacts of non-pharmacologic m... |
<|newrecord|> nctId: NCT06382012 id: 2024-15703 briefTitle: Antiemetic Fosaprepitant To Remedy Nausea and Vomiting acronym: AFTR NV RCT overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2024-12 date: 2024-12 date: 2024-04-24 date: 2024-04-26 name: Montefiore Medical Center class: OTHER briefSummary: The study team ... |
<|newrecord|> nctId: NCT06381999 id: M602011083 briefTitle: Validity and Inter-rater Reliability for Early Recognition of Spasticity Using the Decision Tree Tool acronym: I-REFER overallStatus: COMPLETED date: 2023-10-27 date: 2024-02-26 date: 2024-02-26 date: 2024-04-24 date: 2024-04-24 name: Merz Therapeutics GmbH cl... |
<|newrecord|> nctId: NCT06381986 id: SHJ002-SJP2 briefTitle: Efficacy and Safety of SHJ002 Ophthalmic Solution in the Treatment of Corneal Erosion in Sjogren's Patients overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2025-01 date: 2025-02 date: 2024-04-24 date: 2024-04-24 name: Sunhawk Vision Biotech, Inc. class:... |
SHJ002 is an antisense oligonucleotide to neutralize a specific microRNA. conditions: Corneal Erosion studyType: INTERVENTIONAL phases: PHASE2 allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Double-Blinded, Parallel, Vehicle-Controlled primaryPurpose: TREATMENT masking: QUADRUPLE maskin... |
<|newrecord|> nctId: NCT06381973 id: ELTGOL briefTitle: Ventilation Distribution in COPD Patients During Breathing Exercises overallStatus: RECRUITING date: 2024-04-15 date: 2024-08-01 date: 2024-08-01 date: 2024-04-24 date: 2024-04-25 name: William Poncin, PT, PhD class: OTHER briefSummary: ELTGOL (Slow Expiration wit... |
This study aimed to assess ventilation distribution in right lateral recumbency in patients with chronic obstructive pulmonary disease (COPD), as well as healthy individuals, and investigate the impact of thoracic and abdominal manual pressures during ELTGOL on ventilation distribution. conditions: Chronic Obstructive ... |
<|newrecord|> nctId: NCT06381960 id: 2022LJ014 briefTitle: Clinical Study on the Prevention and Treatment of Postoperative Metastasis of Lung Cancer by Fuzheng Quxie Recipe overallStatus: RECRUITING date: 2023-01-01 date: 2025-12-31 date: 2025-12-31 date: 2024-04-24 date: 2024-04-24 name: Jianhui Tian class: OTHER brie... |
<|newrecord|> nctId: NCT06381947 id: 19092023 briefTitle: Efficacy and Safety of Bempedoic Acid in Association With Anti-PCSK9 and Ezetimibe in Statin-intolerant Patients acronym: BESAFE overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2025-06-30 date: 2025-06-30 date: 2024-04-24 date: 2024-04-24 name: Universi... |
Bempedoic acid is an oral, once-daily prodrug, metabolized in the liver to an active inhibitor of ATP-citrate lyase, blocking cholesterol synthesis upstream of 3-hydroxy-3-methylglutaryl-coenzyme A reductase and thereby increasing hepatic expression of the LDL receptor and decreasing circulating LDL-C levels. |
The CLEAR (Cholesterol Lowering via Bempedoic acid, an ACL-Inhibiting Regimen) Harmony trial demonstrated that bempedoic acid in addition to maximally tolerated statin therapy did not lead to a higher incidence of adverse events compared to placebo and significantly lowered LDL-C levels. In the CLEAR Serenity study, be... |
The synergistic effect of bempedoic acid plus PCSK9 inhibitors has been investigated by one phase 2 trial (NCT03193047), which showed a statistical superiority of bempedoic acid plus evolocumab strategy versus placebo plus evolocumab in terms of percent change in LDL-C up to 2 months. To date, no randomized phase 3 cli... |
The investigators hypothesized that the association of bempedoic acid with PCSK9 inhibitors and ezetimibe may be safe and effective in reducing LDL-C in statin-intolerant patients. conditions: Dyslipidemias conditions: Statin Adverse Reaction conditions: Cardiovascular Diseases conditions: Lipid Metabolism Disorders st... |
<|newrecord|> nctId: NCT06381934 id: 2024-00335; kt23ChristCrain4 briefTitle: Validation of New Diagnostic Indices to Simplify Hyponatremia Therapy Assessment in Patients on Thiazide Diuretics overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2027-04 date: 2027-04 date: 2024-04-24 date: 2024-04-24 name: University ... |
<|newrecord|> nctId: NCT06381921 id: B2023-0046 briefTitle: Objective Integrated Multimodal Electrophysiological Index for the Quantification of Visceral Pain acronym: OIME overallStatus: NOT_YET_RECRUITING date: 2025-05-01 date: 2027-10-31 date: 2029-02-28 date: 2024-04-24 date: 2024-04-24 name: University of Connecti... |
<|newrecord|> nctId: NCT06381908 id: 1-10-72-19-24 briefTitle: The Effects of Combined Energy and Carbohydrate Restriction on Exercise Capacity acronym: CHO-EX overallStatus: RECRUITING date: 2024-04-01 date: 2024-12-15 date: 2024-12-15 date: 2024-04-24 date: 2024-04-24 name: University of Aarhus class: OTHER name: Uni... |
<|newrecord|> nctId: NCT06381895 id: SYSKY-2023-467-01 briefTitle: The Efficacy of Radiomics to Predict Tumor Microenvironment Markers and Comprehensive Therapy for Bladder Cancer overallStatus: COMPLETED date: 2023-05-30 date: 2024-02-01 date: 2024-02-20 date: 2024-04-24 date: 2024-04-24 name: Sun Yat-Sen Memorial Hos... |
<|newrecord|> nctId: NCT06381882 id: MiPac briefTitle: The Role of the Human Microbiome in Patients After Pancreatic Resection. acronym: MiPac overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2026-05-01 date: 2026-11-01 date: 2024-04-24 date: 2024-04-24 name: St. Antonius Hospital class: OTHER briefSummary: The... |
To identify the dynamics of the microbiome, as well as the possibly related short-term and long-term complications, multiple samples at different timepoints are needed from the patients. conditions: Pancreas Cancer conditions: Pancreas Neoplasm conditions: Pancreas Adenocarcinoma conditions: Periampullary Cancer condit... |
<|newrecord|> nctId: NCT06381869 id: CRNHA 2018-2 briefTitle: Bioavailability of Pea Protein in Young and Old Volunteers acronym: NUTRALYS overallStatus: COMPLETED date: 2019-01-10 date: 2019-06-13 date: 2019-06-13 date: 2024-04-24 date: 2024-04-24 name: Roquette Freres class: INDUSTRY name: CRNH Auvergne name: Univers... |
<|newrecord|> nctId: NCT06381856 id: EPM_2024-00227-01 briefTitle: Improving Participation of Autistic Children and Adolescents in the Habilitation Process acronym: IMPAC overallStatus: NOT_YET_RECRUITING date: 2024-09 date: 2025-05 date: 2025-12 date: 2024-04-24 date: 2024-04-24 name: Region Örebro County class: OTHER... |
<|newrecord|> nctId: NCT06381843 id: WSKCT004 briefTitle: A Clinical Study to Evaluate the Safety and Immunogenicity of the Recombinant COVID-19 Vaccine (Sf9 Cell) as a Booster overallStatus: COMPLETED date: 2022-08-02 date: 2023-03-29 date: 2023-12-30 date: 2024-04-24 date: 2024-04-25 name: WestVac Biopharma Co., Ltd.... |
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