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A case of high-grade endometrial stromal sarcoma, confined into an intrauterine polypoid growth, in a woman with a history of breast cancer who was treated with adjuvant tamoxifen.

To optimize future management of this problem we studied 2 poorly recognized factors in the pathogenesis and prognosis of genitourinary malacoplakia in transplant recipients: 1) the probable role of azathioprine as the specific immunosuppressive agent responsible for the pathogenesis of malacoplakia, and 2) the importance of the localization of the disease and its impact on the ultimate prognosis.

Eleven surviving patients were also studied by analysis of serum aminoterminal propeptide of type III procollagen (PIIINP), which is an indicator of fibrogenesis, which is especially suitable for follow-up of fibrotic liver disease.

In cases with or without small perforations, the technique minimizes or decreases fluid flow so that the surgeon has a clearer view of these tissues and can perform more thorough and accurate stripping of deeper layers of tissue.

However, we recently saw two patients with renal tuberculosis treated with ethambutol in whom visual loss from toxic optic neuropathies was severe and irreversible despite careful ophthalmological monitoring and prompt discontinuation of the agent at the first sign of impaired visual function.

We report a case of fulminant hepatic failure associated with didanosine and masquerading as a surgical abdomen and compare the clinical, biologic, histologic, and ultrastructural findings with reports described previously.

Acute chest pain is a common presentation in emergency.

Their attenuation density values were appreciably less than that of calcium and they enhanced slightly with contrast.

On colonoscopy, inflammatory lesions highly compatible with CD were found endoscopically and histologically in all patients.

Ticlopidine-induced aplastic anemia (TIAA) is considered very uncommon.

Patients with large pelvic tumor loads are, according to existing classifications, at high risk to die and to develop drug resistance.

Another important concept behind some medical myths is the overreliance on case reports or authoritative text.

Less common adverse events to dapsone include the idiosyncratic reactions of leukopenia and agranulocytosis, cutaneous eruptions, peripheral neuropathy, psychosis, toxic hepatitis, cholestatic jaundice, nephrotic syndrome, renal papillary necrosis, severe hypoalbuminemia without proteinuria, an infectious mononucleosis-like syndrome, and minor neurological and gastrointestinal complaints.

Lethargy in a newborn: lithium toxicity or lab error?

Single case study.

Confirmation of the suspected drugs that cause hypersensitivity reaction is sometimes difficult.

Likewise, Chinese herbal drugs are considered to be effective and to have few side effects.

Amphotericin B-induced cutaneous leucocytoclastic vasculitis: case report.

Successful use of sodium ferric gluconate in sucrose in a patient with multiple drug allergies.

Rapamycin/sirolimus (SR), trade named Rapammune (Wyeth-Ayerst, Sydney, Australia), is a potent immunosuppressive drug associated with myelosuppression, hypertension, hyperlipidemia, and infection.

Caution should be taken when designing estrogen-related experiments involving Brown Norway rats and other potentially sensitive strains.

We present a case of a diabetic patient taking glyburide who was prescribed ciprofloxacin and developed prolonged hypoglycemia, which persisted for over 24 hours.

A child in whom a phenobarbital hypersensitivity drug reaction developed which consisted of fever, a pruritic desquamating erythrodermic rash, alopecia, icterus, protein-losing enteropathy, myositis, and nephritis, is described.

A 7-year-old boy developed a severe unilateral grand mal seizure at the age of 5 years (phenobarbitone therapy); 1.5 years later valproate (2-propylpentanoic acid, VPA) was added to the therapy.

Shortly after chemotherapy and an injection of pegfilgrastim, the patient developed poorly defined, rapidly progressive erythema, edema, and pain in his right forearm.

Primary cutaneous coccidioidomycosis and subsequent drug eruption to itraconazole in a dog.

Neuroleptic malignant syndrome (NMS) is a rare but potentially serious complication of neuroleptic drugs.

The authors report the case of a 61-year-old man with CML treated with imatinib with a good response, and they switched to dasatinib after grade 4 hepatic toxicity.

BACKGROUND: Nocardia exalbida was first reported in 2006.

Interference with the cortisol axis by the microtubule antagonist, CPH82.

Salmonella oslo.

The coexistence of acute myeloid leukemia (AML) and CLL in the same patient has been occasionally reported.

RESULTS: In a 22-year-old Thai woman with Graves' disease, tinnitus, hearing impairment in the left ear (with progression to the right ear), and vertigo developed after 3 years of therapy with PTU.

The use of sulfonylurea medications in the treatment of type 2 diabetes mellitus is common.

CONCLUSION: Tamoxifen may cause malignant transformation of endometriosis through atypical endometriosis even in the postmenopausal state.

The symptoms arose within 3-5 min after immersion in water, as a white sponge-like appearance, and resolved after a variable drying period.

Majocchi's granuloma is a condition with chronic erythematous and indurated plaques that is a result of the rupture of a dermatophyte-infected infundibulum as a result of trauma.

CASE: We present an 11-year old male with Budd-Chiari syndrome who experienced profound worsening of chronic aphthous ulcers after immunosuppressive therapy was changed from tacrolimus to sirolimus.

The DLK in this patient is delayed longer than typically reported in the literature.

Hypersensitivity reactions due to chloramphenicol are rarely reported in the literature.

The patient recovered completely following withdrawal of antacids and sucralfate and short-term treatment with phosphate.

The use of high potency topical steroids for the treatment of oral vesiculoerosive diseases seems to have been a contributing factor in two of these cases.

METHODS: This is a retrospective, open-label study of 24 patients; 18 of whom were not responding to accepted medication for treatment of their TS and six of whom were receiving no medication.

A young patient experienced marked sinus tachycardia while smoking marijuana and receiving therapeutic doses of nortriptyline.

The main clinical features of this 58-year-old female patient were laboratory evidence of leucopenia and cholestasis, and biopsy features of fatty liver parenchyma degeneration with granulocytic portal infiltration and bile stasis, demonstrated 20 days after the initiation of antithyroid therapy with 20 mg methimazole daily.

The 9 other reported cases of D-penicillamine induced rapidly progressive glomerulonephritis have been reviewed.

Subacute cholestatic hepatitis likely related to the use of senna for chronic constipation.

Of the 10 patients with MDS, 6 were suffering from refractory anaemia with sideroblasts (RAS) and 4 from refractory anaemia with an excess of blasts.

A clinical and microbiologic response occurred when anticoagulation therapy with heparin was added to the treatment regimen.

However, in the mid-to-late 1980s, a series of letters to the editor and case reports announced an association between tamoxifen therapy in women with breast cancer and the development of endometrial carcinoma.

Although major hazards of treatment of hypophosphatemic osteomalacia with phosphate and calcitriol are secondary hyperparathyroidism and vitamin D intoxication, potassium loss also should be kept in mind.

He developed immune-mediated diabetes mellitus with low C-peptide and positive antiglutamic acid decarboxylase antibody after completion of therapy.

It is unknown whether the vitamin K content or malabsorption of warfarin is the mechanism of resistance.

A 36-year-old man being treated with cisplatinum, vinblastine, and bleomycin for testicular carcinoma developed a dense left homonymous hemianopsia, encephalopathy, and a partial nondominant parietal lobe syndrome.

CONCLUSION: The recognition of this atypical presentation with a combination of opthalmoscopic, angiographic and OCT findings may avoid inappropriate diagnosis and treatment with corticosteroids.

To date little has been reported about the risk of therapy-related leukaemia (t-AML) in children receiving oral etoposide therapy.

Diagnosis requires CT scan and direct aspiration and culture of the liver abscess.

The patient responded to aluminum chloride applied topically.

He had a history of subtotal gastrectomy.

I suggest that prior to giving amphotericin B to patients with resistant kala-azar their electrolyte imbalance should be corrected.

Behavioral side effects associated with clonazepam may include agitation, aggression, hyperactivity, irritability, property destruction, and temper tantrums.

The patients were followed up for an average of 32 months (range 16-75 months).

Although they had complex medical problems, the high serum concentrations of ampicillin at the time of seizures without their recurrence after discontinuing the antibiotic suggest that the seizures were related to the ampicillin therapy.

A follow-up cerebral angiogram demonstrated a small AVM arising off a branch of the pericallosal artery and a small arteriovenous fistula arising off the costal marginal branch.

Seizure with hyponatremia in a child prescribed desmopressin for nocturnal enuresis.

This case demonstrates that severe anterior uveitis may develop after LASIK and needs prompt and vigorous management for resolution.

Symptoms resolved spontaneously and completely after 48 h.

Steroid hormone deprivation potentially contributed to neovascularization and bowel involvement.

Three patients, in whom tumour overkill by cytotoxic treatment, including high dose methotrexate with folinic acid rescue, resulted in the 'phosphate shower syndrome' (hyper-uricaemia, hyperkalaemia and hyperphosphataemia with hypocalcaemia and tetany, with metabolic acidosis and acute renal impairment) are described.

Interferon-alpha affects the immune response in post-transplant lymphoproliferative disorder.

Visual hallucinations associated with zonisamide.

The syndrome of irreversible lithium-effectuated neurotoxicity (SILENT).

Treatment with local antibiotics was initiated but the condition of the eye worsened, ultimately resulting in corneal perforation.

A female patient with HER2 positive, metastatic breast cancer presented with pulmonary infiltrates, and a plural effusion dyspnoea after several months of trastuzumab treatment.

The former had a slowly progressive course, did not respond to amphotericin B (AB), and died; the latter improved after a prolonged course of liposomal-AB.

A 44-year-old woman is described in whom amiodarone, disopyramide, and quinidine, administered alone separately, induced atypical ventricular tachycardia (AVT, torsade de pointes).

We are unaware of previous reports of P. avidum hip arthritis.

We ultimately speculated that corticosteroid withdrawal induced the depressive symptoms in this case.

We present two cases of anaphylaxis under anaesthesia where return of spontaneous circulation was refractory to epinephrine, but occurred following the administration of the alpha-agonist metaraminol.

Intravenous thrombolytic therapy has become standard treatment for acute myocardial infarction (AMI).

Treatment was stopped after 2 weeks.

We report three cases of ophthalmic problems that were treated with a short course of oral corticosteroids and which resulted in the development of hyperosmolar hyperglycemic nonketotic coma.

A 51-year old physically fit woman experienced angio-oedema and hypotensive shock after irbesartan ingestion requiring noradrenaline infusion.

Quinine is universally used for the very common symptom of night leg cramps.

We report the first case of fulminant adult respiratory distress syndrome (ARDS) associated with pegylated interferon alpha-2a (pegIFNalpha-2a) and ribavirin use for hepatitis C, complicated by subsequent and ultimately fatal sepsis and multiorgan failure.

This case is reported in support of the dopamine hypothesis for the etiology of schizophrenia.

CONCLUSION: A 37-year-old African- American man with G6PD deficiency developed hemolytic anemia, hepatitis, orthostatic hypotension, and aseptic meningitis simultaneously after using trimethoprim-sulfamethoxazole.

Further exacerbations of the rheumatic condition may be induced by treatment of the cancer.

If suspected, prompt medical assessment should be arranged, including serum glucose and cortisol measurement.

On the 4th day after the infusion, VWF antigen and VWF ristocetin cofactor increased to 40 and 78% of the control, respectively, and dental extractions were performed successfully.

The authors report the first case of bucillamine-induced giant mammary hyperplasia.

Treatment of periocular capillary hemangioma with topical clobetasol propionate.

On the fifth day after administration of a high dose of ARA-C (2 g/m2 intravenously every 12 hours), she developed bullous lesions on the hands and soles that disseminated, evolving to necrosis, sepsis, and death on the 22nd day.

The day after clozapine was stopped, while he was still receiving clomipramine 150 mg/d, he began behaving oddly, started sweating profusely, shivering, and became tremulous, agitated, and confused.

These idiosyncratic reactions may be transient and do not always necessitate drug discontinuation.

A 40-year-old man with advanced HIV infection and Mycobacterium avium complex infection experienced rapid cognitive decline after commencement of ethambutol, and symptoms fully resolved with cessation.

The remaining clinical scenarios included intravenous catheter sepsis and factitious disorders.

Carbamazepine-induced systemic lupus erythematosus.

The authors describe a case of combined lithium and haloperidol toxicity characterized by hyperpyrexia, severe rigidity, mutism, and development of irreversible tardive dyskinesia.

No cardiovascular disorder with the exception of minor ischemic changes in ECG was revealed before treatment.