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A case is reported in which severe hypocalcemia, with a low plasma parathyroid hormone (PTH) concentration, resulted from the therapeutic use of magnesium sulfate for toxemia of pregnancy.

Clearance and adverse effects of efavirenz are associated with CYP2B6-G516T polymorphism.

After receiving 3 doses of ifosfamide/mesna, she was found to be unresponsive.

The patient was diagnosed with carbamazepine toxicity related to the introduction of ritonavir.

PURPOSE: The case of a patient who developed aseptic meningitis, hemolytic anemia, hepatitis, and orthostatic hypotension simultaneously during treatment with trimethoprim-sulfamethoxazole is described.

CONCLUSIONS: Symptoms and pathologic changes of colitis are associated with exposure to rofecoxib.

In case 1, a total daily dose of 25 mg sertraline, with nondetectable sertraline and desmethylsertraline blood levels, resulted in a doubling of the lamotrigine blood level with symptoms of toxicity.

Recurrent septicemia with lethal outcome during and after cyclosporine therapy in severe ulcerative colitis.

Concomitant use of statins and cyclosporine should be avoided.

We report a 45-year-old psoriasis patient who developed eruptive mollusca contagiosa during an antipsoriatic treatment with efalizumab.

Enalapril-induced anemia in two kidney transplant recipients.

We report a patient of organic bipolar affective disorder who developed hiccups with the atypical antipsychotic aripiprazole.

Enoxaparin therapy was discontinued, and the patient was maintained on oral warfarin.

Retinal abnormalities, including retinal hemorrhage and "cotton-wool" spots, often occur within the first 8 weeks in the course of interferon therapy in patients with chronic hepatitis C.

Neurologic toxicity associated with hepatic artery infusion HAI of FUdR.

The association with prolonged unopposed estrogen-like stimulation with tamoxifen as a possible factor in the development of ovarian endometrioid carcinoma is discussed.

With careful sequential clinical and laboratory monitoring, even this type of cerebrospinal fluid shunt infection can be eradicated without catheter removal and replacement.

Methotrexate (MTX) is a commonly used second line agent for RA, and there have been several recent reports of Epstein-Barr virus (EBV)-associated polyclonal B cell lymphoproliferative disorder in MTX-treated RA patients.

Magnetic resonance imaging revealed regional kyphosis and large swollen paraspinal muscles impinging on the spinal cord without epidural hematoma.

Almost all of the suspected adverse drug reactions (ADR) from 1% lindane have involved substantial misuse.

The incidence of oral-verapamil-induced hypotension in the presence of concomitant beta-adrenergic blockade by the oral route is quite rare.

Such anagen effluvium with lichenoid eruption following INH therapy has not been observed previously.

The most common cutaneous adverse event is an acneiform eruption, which occurs in more than 50% of cases.

Her initial EEG showed a pattern of spindle coma with some responsivity of the background.

Mecasermin [rDNA] (Increlex; Tercica, Inc.) is recombinant insulin-like growth factor-I (IGF-I) that has been approved to treat growth failure in children with severe primary IGF-I deficiency.

At this time most of the DGTX in serum was FAB-bound.

Little inflammatory change was noted in either the epithelial or stromal layers of the failed graft.

In CAPD patients with candida peritonitis, fluconazole seems to offer several advantages over other antifungal drugs.

When the trazodone was reduced, the involuntary movements promptly ceased.

a 67-year-old man with bipolar disorder developed a Creutzfeldt-Jakob like syndrome during lithium carbonate treatment.

Proconvulsive tendency of imipenem/cilastatin is one of its well-known side effects.

The case cited here highlights the need for continued awareness education for physicians who may use ceftriaxone to treat common illnesses such as acute exudative tonsillitis and otitis media in children.

Mechanisms and triggering factors of hypoglycaemia induced by mefloquine and some other anti-malarial quinine analogues are discussed.

We present two cases in which both patients suffered with CLS, which we believe was caused following administration of granulocyte colony-stimulating factor, to our knowledge not described in the intensive care patient previously.

We report a case of a 64-year-old man with secondary adrenocortical insufficiency who has been on a chronic transdermal fentanyl treatment because of sciatic pain syndrome.

METHODS: Endoscopic retrograde cholangiography was performed to define the proximal and distal extent of intraductal tumor.

She underwent emergent surgical valve replacement.

In one case the recognition of anterior vitreous face contact to the cornea was delayed by the severity of the corneal edema.

In case 1, a total daily dose of 25 mg sertraline, with nondetectable sertraline and desmethylsertraline blood levels, resulted in a doubling of the lamotrigine blood level with symptoms of toxicity.

While both amiodarone and digoxin can cause permanent visual changes, the ocular effects are often reversible.

The authors report a further case of methimazole-associated liver damage and present a brief review of eleven previous cases found in the literature.

Paralytic ileus in patients undergoing bortezomib treatment has been reported, although a definite attribution to bortezomib administration has not been established.

This severe illness was likely caused by minocycline, and we speculate that minocycline may have acted as a superantigen, causing lymphocyte over-activation and massive cytokine release.

We report a patient in whom the anti-depressant trazodone hydrochloride (Molipaxin, Roussel), a serotonin antagonist, provoked generalized pustular psoriasis (GPP).

Reversible posterior leukoencephalopathy syndrome (RPLS) is a syndrome manifested by headache, nausea, vomiting, seizures, cortical blindness, and visual disturbances.

At explant, all four systems had clots adherent to the surface of the tubing and connectors on the pump outflow side of the circuit.

De novo inflammatory bowel disease after pediatric orthotopic liver transplant: a case report.

Teicoplanin-induced agranulocytosis that followed vancomycin-induced agranulocytosis suggests a possible cross-reactivity between the 2 drugs.

A 53-year-old man developed lower leg edema 4 weeks after rosiglitazone was increased from 4 mg once/day to 4 mg twice/day.

Corticosteroid therapy was continued for 8 months since there was still improvement of pulmonary function studies.

Acute non-lymphocytic leukemia in patients with ovarian carcinoma following long-term treatment with Treosulfan (= dihydroxybusulfan).

We present a patient with typical aquagenic pruritus who responded well to PUVA, and who has remained well controlled on infrequent maintenance.

Knowledge of the stage of dental development at the time of oncology treatment and the type of therapy allows the clinician to predict dental effects of the chemoradiation.

The current study investigated the visual fields and visual electrophysiology of eight patients with known vigabatrin-attributed visual field loss, three of whom were reported previously.

Tardive seizure and antibiotics: case reports and review of the literature.

Affected persons usually are on chronic steroid treatment and in the fifth to seventh decades of life.

Bromide intoxication secondary to pyridostigmine bromide therapy.

Eruptive epidermoid cysts resulting from treatment with imiquimod.

Candida-induced denture stomatitis usually does not reflect any deep-seated, systemic abnormality, the dentures being the primary predisposing condition.

A Flexiflo Inverta percutaneous endoscopic gastrostomy tube was successfully inserted by pull technique.

However, none were as severe as the first rash.

We present findings from three patients who experienced a psoriasiform eruption apparently due to the antiepileptic agents sodium valproate and carbamazepine.

RESULTS: Ten eyes in 6 patients with late-onset interface inflammation and increased intraocular pressure were identified.

This article describes the case of a 25-year-old man found dead at home who had been prescribed olanzapine for schizophrenia.

Around 1990, psychologists and educators began to notice increasing use of methylphenidate by students.

Interaction between tacrolimus and nefazodone in a stable renal transplant recipient.

DISCUSSION: Toxic epidermal necrolysis is an infrequent, yet often fatal, severe, systemic, cutaneous disease most often the result of an adverse drug reaction.

These cases suggest the possibility that, in some patients, leukopenia or agranulocytosis during olanzapine treatment might be dose-related.

We cared for a patient with progressive renal impairment who presented with blurred vision, QRS broadening and cardiac failure due to chronic cibenzoline intoxication.

The two patients underwent several courses of pulse corticosteroid therapy, each course consisting of three days of methylprednisolone 1000 mg daily, resulting in visual recovery to some extent.

Ultrasound study revealed enlarged kidneys with increased echogenity and loss of corticomedullary differentiation.

We describe a patient with CREST syndrome (calcinosis, Raynaud's phenomenon, esophageal dysfunction, sclerodactyly, and telangiectasia) who paradoxically experienced worsening of Raynaud's phenomenon when using yohimbine for ED.

Based on the clinical status of the patient, it was suspected that several conditions contributed to the abnormal hypersensitivity to warfarin.

It gives the radiological and CT scan findings and the important role played by them in the diagnosis of this syndrome.

While approximately 70% of patients with schizophrenia and other psychotic disorders show a clear-cut reduction of symptoms in clinical trials, there is considerable variation in individual patient outcome, ranging from complete remission to absolute refractoriness.

An evaluation of ovarian structure and function should be considered in women of reproductive age being treated with valproate for epilepsy, especially if they develop menstrual cycle disturbances during treatment.

We report a case of successful surgical management of arterial thrombosis after percutaneous thrombin injection of a femoral artery pseudoaneurysm in a 69-year-old woman.

A dapsone hypersensitivity syndrome, consisting of fever, headache, nausea, vomiting, lymphadenopathy, hepatitis, hemolysis, leukopenia, and mononucleosis, has been described in patients treated with the drug for leprosy.

Tacrolimus (FK506), an immunosuppressant, has been associated with mutism in adults after liver transplant.

Four Chinese female patients who suffered from manic-depressive disorder and underlying autoimmune thyroiditis developed transient episodes of thyrotoxicosis during maintenance lithium therapy.

We review the literature on previously reported cases of cutaneous necrosis after injection of standard interferon alfa or pegylated interferon alfa-2b and discuss the different pathophysiologic mechanisms that might be involved.

CD4 T-lymphocyte depletion, myelosuppression, and subsequent severe infections are the major side effects of fludarabine phosphate therapy.

We present a case of acute epinephrine toxicity resulting in acute myocardial ischemia in a young boy with combined variable immunodeficiency syndrome who developed severe allergic reaction to intravenous immunoglobulin, and was subsequently given epinephrine by mistake intravenously rather than subcutaneously.

In clinical practice, serum level monitoring of anticonvulsant drugs is usually adequate.

When SASP was changed to 5-aminosalicylic acid (5-ASA), his skin eruptions were resolved, however, he developed weakness and atrophy in his right arm as well as progressive worsening of the dysesthesia in his legs and gait disturbance.

During hospitalization the patient developed hemolytic anemia (Coombs positive) and lung metastases.

We report a case of generalized cutaneous sclerosis associated with muscle and oesophageal involvement in a patient exposed to herbicides containing bromocil, diuron and aminotriazole.

It is concluded that the aforementioned pathological manifestations were due to chemotherapy and included a pulmonary adverse reaction, a feature never previously associated with oxaliplatinum and 5-fluorouracil regimens.

Disseminated varicella infection is a potentially life-threatening complication of chronic high-dose corticosteroid (CS) or immunosuppressive therapy.

The patient was then dialyzed for presumed acyclovir toxicity.

During the course of therapy, the patient showed rapid onset of oliguria, dizziness, edema, and a pre-shock state.

The results of this pilot study demonstrate that fluoxetine safely and effectively suppresses cataplexy and reduces the need for other, less desirable, anticataplectic agents.

However, an association of Ritalin with glaucoma has been reported.

A patient with psoriasis is described who had an abnormal response to the glucose tolerance test without other evidence of diabetes and then developed postprandial hyperglycemia and glycosuria during a period of topical administration of a corticosteroid cream, halcinonide cream 0.1%, under occlusion.

OBJECTIVE: To describe two cases of rhabdomyolysis in patients taking lovastatin that were precipitated by the use of the newer macrolide antibiotics clarithromycin and azithromycin.

Management of hypophosphatemia induced by high-flux hemodiafiltration for the treatment of vancomycin toxicity: intravenous phosphorus therapy versus use of a phosphorus-enriched dialysate.

Previous studies showed that clevudine has potent and sustained antiviral activity without causing viral resistance.

Treatment of carbimazole-induced agranulocytosis and sepsis with granulocyte colony stimulating factor.

After 5-ASA was discontinued, the polyneuropathy symptoms recovered gradually.

One patient on ouabain also developed cardiomyopathy.