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{ "abstract": "OBJECTIVES\nThe aim of the study was to determine if isosorbide-5-mononitrate (IS-5-MN) 120 mg, taken once daily for 7 days, is associated with evidence of endothelial dysfunction and whether this effect is determined by increased free radical production.\n\n\nBACKGROUND\nTolerance to nitroglycerin is ...
{ "abstract": "Damage and dysfunction of the vascular endothelium critically influence clinical outcomes after ischemia and reperfusion (I/R). Brief exposure to organic nitrates can protect the vascular endothelium from I/R injury via a mechanism that is similar to ischemic preconditioning and is independent of hemod...
{ "abstract": "Obesity and its associated complications, which can lead to the development of metabolic syndrome, are a worldwide major public health concern especially in developed countries where they have a very high prevalence. RIP140 is a nuclear coregulator with a pivotal role in controlling lipid and glucose m...
{ "abstract": "To the Editor: Radiofrequency thermocoagulation (RFTC) can be effectively used to treat chronic pain [1]. However, it may lead to thermal destruction of tissue surrounding the nerve [2]. Thus, correct identification of the targeted tissue is of great importance. For this purpose, imaging methods such a...
{ "abstract": "Anterior cutaneous nerve entrapment syndrome (ACNES) is a commonly underdiagnosed and undertreated chronic state of pain. This syndrome is characterized by the entrapment of the cutaneous branches of the lower thoracoabdominal intercostal nerves at the lateral border of the rectus abdominis muscle, whi...
{ "abstract": "Hematocrit data are relatively easily obtained from blood samples of pinnipeds but differences in methodology and variable physiological conditions of the subjects can significantly alter their values. This two-fold problem makes comparative data and modeling efforts difficult. To quantify the difficul...
{ "abstract": "INTRODUCTION\nTo determine the oropharyngeal carriage rates and serogroups of Neisseria meningitidis in primary school children in Manisa, Turkey as well as the prevalence and penicillin resistance of N. meningitidis.\n\n\nMATERIALS AND METHODS\nThroat swabs obtained from 1128 children were cultured an...
{ "abstract": "Meningococcal disease is a global burden and remains one of the leading infectious causes of death in children, with an estimated annual death rate of 170,000 worldwide. Despite these figures, the management of children with severe meningococcal sepsis and septic shock remains suboptimal. This review p...
{ "abstract": "The determination of the PGF of the queue length distribution often requires the zeros on and within the unit circle of functions of the type z^s-A(z), where A(z) is a PGF. We present an elementary proof of the existence of these zeros including series A(z) with a radius of convergence of one.", "cor...
{ "abstract": "Publisher Summary This chapter provides information on the purification of Rhizobium cytochromes P-450. The cytochrome P-450 of nitrogen fixing Rhizobium bacteroids (legume root nodule bacteria) was the first P-450 to be extracted and purified without the use of detergents. Nevertheless, it has been li...
{ "abstract": "Unraveling of microbial genome data has indicated that two distantly related truncated hemoglobins (trHbs), HbN and HbO, might occur in many species of slow‐growing pathogenic mycobacteria. Involvement of HbN in bacterial defense against NO toxicity and nitrosative stress has been proposed. A gene, enc...
{ "abstract": "Abstract Chemiluminescence occurs on autoxidation of oxygenated ferrous cytochrome P450cam and is abolished by reagents that scavenge free radicals, by superoxide dismutase and singlet oxygen quenchers. We attribute the chemiluminescence to the decay of an excited singlet oxygen which arises from a sup...
{ "abstract": "Flowering time is an important ornamental trait for chrysanthemum (Chrysanthemum morifolium, Dendranthema x grandiflorum) floricultural production. In this study, CmNRRa, an orthologous gene of OsNRRa that regulates root growth in response to nutrient stress in rice, was identified from Chrysanthemum a...
{ "abstract": "Additional index words. Dendranthema × grandiflorum, photomorphogenesis, light quality, plant growth regulation Abstract. The interactions of light quality and growing season on growth and carbohydrate content of chrysanthemum (Dendranthema × grandiflorum (Ramat.) Kitamura) plants were evaluated using ...
{ "abstract": "To analyze the association between the results of routine inspections and foodborne outbreaks in restaurants, we conducted a matched case-control study using available data from Seattle-King County, Washington. Case restaurants were facilities with a reported foodborne outbreak between January 1, 1986 ...
{ "abstract": "There are very few studies that have directly analyzed the effects of dietary intake of slowly digestible starches on metabolic parameters of animals. The present study examined the effects of slowly digestible starch with high amylose content (referred also as amylose starch) either alone, or in combi...
{ "abstract": "In recent years, Drosophila melanogaster has emerged as a model for studies on aluminum toxicity. The current study aimed to disclose the mechanisms of aluminum toxicity in D. melanogaster at larval and adult stages and examined the potential protective effects of dietary alpha-ketoglutarate (AKG). Fli...
{ "abstract": "Feeding behavior is influenced primarily by two factors: nutritional needs and food palatability. However, the role of food deprivation and metabolic needs in the selection of appropriate food is poorly understood. Here, we show that the fruit fly, Drosophila melanogaster, selects calorie-rich foods fo...
{ "abstract": "OBJECTIVE\nTo find and assess quality-rating instruments that can be used by health care consumers to assess websites displaying health information.\n\n\nDATA SOURCES\nSearches of PubMed, the World Wide Web (using five different search engines), reference tracing from identified articles, and a review ...
{ "abstract": "OBJECTIVE\nTo understand and address patients' need for information surrounding ambulatory-care visits.\n\n\nDESIGN\nThe authors conducted two patient focus groups regarding patient education. The first covered general information needs of patients and the second explored their reactions to a computer-...
{ "abstract": "Objectives To estimate the prevalence of healthcare use and associated factors in the Manaus metropolitan region and to describe the reasons for lack of access. Design Cross-sectional population-based study. Setting A survey conducted between May and August of 2015 in eight cities from Manaus metropoli...
{ "abstract": "To study the modification method of the measured concentration of organics and the effect of organics on the shortcut nitrification in wastewater containing NO2- , the effect of NO2- on the measurement of organics were investigated by preparing glucose solution, sodium nitrite solution and glucose-nitr...
{ "abstract": "In the treatment of soybean wastewater,study was made on the nitrification and denitrification at higher temperature (31±1) ℃ in sequencing batch reactor (SBR) process and on the feasibility of applying ORP and pH value as control parameters of shortcut nitrification and denitrification process.The r...
{ "abstract": "A nitrification process under low dissolved oxygen (DO) concentration is proposed in a completely stirred biofilm reactor. The reactor was fed with a synthetic wastewater containing 250 mg NH\\d4–N/L. A stable nitrite accumulation in the effluent was obtained during >110 days’ operation; NO\\d2–N(NO\\d...
{ "abstract": "“…someday someone will die—and wall or not—the public will not understand why we were not more effective and throwing every resource we had at certain ‘problems’.” –Email from an angry FBI agent to...", "corpus_id": 154942285, "title": "A Failure to Communicate: 9/11 and the Tragedy of the Informat...
{ "abstract": "Research on transactive memory systems (TMS) has been conducted in a variety of teams, a range of task types and increasingly, in settings around the world. Despite this proliferation, there has been relative inattention to contextual factors that produce TMS and explain heterogeneity in the TMS to tea...
{ "abstract": "In order to investigate the spinal cord surface PO2 (sPO2) reaction to hypovolemic hypotension, nine female pigs (25 kg bw) were premedicated, anesthetized, intubated and artificially ventilated with N2O:O2 = 3:1. Following laminectomy from L3 to L5, sPO2 was measured on the dorsal side of the exposed ...
{ "abstract": "In this paper, we present a monocular visual-inertial odometry algorithm which, by directly using pixel intensity errors of image patches, achieves accurate tracking performance while exhibiting a very high level of robustness. After detection, the tracking of the multilevel patch features is closely c...
{ "abstract": "Robust and accurate visual-inertial estimation is crucial to many of today's challenges in robotics. Being able to localize against a prior map and obtain accurate and drift-free pose estimates can push the applicability of such systems even further. Most of the currently available solutions, however, ...
{ "abstract": null, "corpus_id": 45163449, "score": -1, "title": "Stabilization of a Quadrotor With Uncertain Suspended Load Using Sliding Mode Control" }
{ "abstract": "The effective measurement of pixel's sharpness is a key factor in multi-focus image fusion. In this paper, a gray image is considered as a two-dimensional surface, and the neighbor distance deduced from the oriented distance in differential geometry is used as a measure of pixel's sharpness, where the ...
{ "abstract": "Images acquired by heterogeneous image sensors may provide complementary information about the scene, for instance, the visual image can provide personal identification information like the facial pattern while the infrared (IR) or millimeter wave image can detect the suspicious regions of concealed we...
{ "abstract": "Almost all current dependency parsers classify based on millions of sparse indicator features. Not only do these features generalize poorly, but the cost of feature computation restricts parsing speed significantly. In this work, we propose a novel way of learning a neural network classifier for use in...
{ "abstract": "The conventional approach to overfishing is for government to impose a top-down management system on the industry. This may involve a state agency setting overall catch quotas and then allocating shares to fishing enterprises, or creating some form of market framework that allows catch shares to be tra...
{ "abstract": "This paper examines the problems of spatial competition in the beekeeping segment of the New Zealand manuka honey industry. Competition between two close apiaries results in negative reciprocal production externalities. A basic geometric model of spatial competition between two apiaries is developed. V...
{ "abstract": "Leachate nutrients from the nursery of containerized tree seedlings result in risks of inefficient fertilization through nutrient loss and contamination of ground water. In the present study, seedlings of Buddhist pine (Podocarpus macrophyllus) and Japanese maple (Acer palmatum) were cultured in contai...
{ "abstract": "Time-lapse imaging is a powerful tool for studying cellular dynamics and cell behavior over long periods of time to acquire detailed functional information. However, commercially available time-lapse imaging systems are expensive and this has limited a broader implementation of this technique in low-re...
{ "abstract": "Recent advancements in bioanalytical techniques have led to the development of novel and robust diagnostic approaches that hold promise for providing optimal patient treatment, guiding prevention programs and widening the scope of personalized medicine. However, these advanced diagnostic techniques are...
{ "abstract": "Techniques used in assisted reproductive technology such as In-Vitro- Fertilization (IVF) process, often only replicate the biomechanical environment for embryo. Despite its importance, the biomechanics of the Oviduct tissue that is usually called Fallopian Tube in Human, the natural site of fertilizat...
{ "abstract": "Experimental processes to collect and process proteomics data are increasingly complex, while the computational methods to assess the quality and significance of these data remain unsophisticated. These challenges have led to many biological oversights and computational misconceptions. We developed a c...
{ "abstract": "Currently, there is a major effort to map protein-protein interactions on a genome-wide scale. The utility of the resulting interaction networks will depend on the reliability of the experimental methods and the coverage of the approaches. Known macromolecular complexes provide a defined and objective ...
{ "abstract": "“If it were not for the great variability among individuals medicine might as well be a science and not an art.” The thoughts of Sir William Osler in 1892 reflect the view of medicine over the past 100 years. The role of physicians in making the necessary judgements about the medicines that they prescr...
{ "abstract": "In this letter, results on the autonomous response of a third-order digital filter with two’s complement arithmetic realized as a first-order subsystem cascaded by a second-order subsystem are reported. The behavior of the second-order subsystem depends on the pole location and the initial condition of...
{ "abstract": "It is observed that the third-order digital filter with an overflow non-linearity has a much richer dynamics than the second-order digital filter. Computer simulations show that the third-order non-linear system can exhibit incredibly complicated fractal geometrical patterns. A three-dimensional trajec...
{ "abstract": "It is well known that the autonomous response of a second-order digital filter with two's complement arithmetic may exhibit chaotic behavior. In this paper, results of the step-response case are presented. Despite the presence of the overflow nonlinearity, it is found that the step-response behaviors c...
{ "abstract": "3,4-Methylenedioxymethamphetamine (MDMA, �ecstasy�) releases serotonin and norepinephrine. MDMA is reported to produce empathogenic and prosocial feelings. It is unknown whether MDMA in fact alters empathic concern and prosocial behavior. We investigated the acute effects of MDMA using the Multifaceted...
{ "abstract": "Methylenedioxymethamphetamine (MDMA) is generally described as non-addictive. However, this report describes three cases in which criteria for dependence were met. A wider understanding that MDMA can be addictive in rare cases is important as very heavy use may cause lasting neuronal changes. This risk...
{ "abstract": null, "corpus_id": 5594856, "score": -1, "title": "Effectiveness of Adaptive Passivity-based Trajectory Tracking Control Of a Cable-suspended Robot" }
{ "abstract": "BACKGROUND\nActivation of the SAPK/MAPK signaling pathway by pro-inflammatory cytokines is known to induce apoptosis in cultured articular chondrocytes. C-28/I2, an immortalized human juvenile chondrocyte cell line was employed to determine the extent to which recombinant human (rh) forms of the pro-in...
{ "abstract": "IntroductionThe importance of mechanical signals in normal and inflamed cartilage is well established. Chondrocytes respond to changes in the levels of proinflammatory cytokines and mechanical signals during inflammation. Cytokines like interleukin (IL)-1β suppress homeostatic mechanisms and inhibit ca...
{ "abstract": "In areas endemic for schistosomiasis, the population dynamics of the snail intermediate hosts have a direct effect on parasite transmission. The present study focused on the potential for neonatal Biomphalaria glabrata snails to become infected with Schistosoma mansoni and to produce cercariae under va...
{ "abstract": "We study the retention effects of the Australian military’s decision to remove a 20-year cliff-vesting requirement from their retirement system in 1991. We follow to the present individuals who self-selected into and out of the 20-year cliff-vesting plan, as well as those who were forced out of the pla...
{ "abstract": "Limited Electronic Distribution Rights This document and trademark(s) contained herein are protected by law as indicated in a notice appearing later in this work. This electronic representation of RAND intellectual property is provided for noncommercial use only. Unauthorized posting of RAND electronic...
{ "abstract": "Chaotic dynamics in grounded base bipolar junction transistor Colpitts oscillator was extensively studied due to its implementation simplicity and high frequency capability. Some synchronization methods were also proposed, but they suffer from high sensitivity both to channel noise and parameter mismat...
{ "abstract": "A common form of heart disease in the adult Bantu population that is served by this hospital is,we believe, based on chronic malnutrition. It forms a well defined clinical syndrome that has already been described in some detail (Gillanders, 1951). Briefly, patients with heart disease of this kind have ...
{ "abstract": "Cardiac failure in young persons lacking the usual features of organic heart disease or associated renal lesions has frequently been ascribed to isolated (Fiedler's) myocarditis. A study of the reported cases of isolated myocarditis indicates a heterogeneous disease group related to known and to unknow...
{ "abstract": "We have assembled two BAC vectors containing a single fragment spanning the entire CFTR locus and including the upstream and downstream regions. The two vectors differ in size of the upstream region, and were recovered in Escherichia coli, with intact BAC DNAs prepared for structural and functional ana...
{ "abstract": "White-dwarf stars are the end product of stellar evolution for most stars in the Universe. Their interiors bear the imprint of fundamental mechanisms that occur during stellar evolution. Moreover, they are important chronometers for dating galactic stellar populations, and their mergers with other whit...
{ "abstract": "We present a catalogue of white dwarf candidates selected from the second data release of Gaia (DR2). We used a sample of spectroscopically confirmed white dwarfs from the Sloan Digital Sky Survey (SDSS) to map the entire space spanned by these objects in the Gaia Hertzsprung–Russell diagram. We then d...
{ "abstract": "The number of stars in the spheroid of our Galaxy appears to increase steeply for smaller masses, with no evidence of a turnover in a simple power-law distribution down to 0.14⊙, the limit of detectability. The measured rotation curve of the Galaxy at the Sun suggests that the mass function cannot be e...
{ "abstract": "Demand Side Management (DSM) has been recognized for its potential to counteract the intermittent nature of renewable energy, increase system efficiency, and reduce system costs. While the popular approach among academia adopts a social welfare maximization formulation, the industrial practice in the U...
{ "abstract": "The intermittent nature of renewable energy has been discussed in the context of the operational challenges that it brings to electrical grid reliability. In contrast, Demand Side Management (DSM) with its ability to allow customers to adjust electricity consumption in response to market signals has of...
{ "abstract": "Demand side management will be a key component of future smart grid that can help reduce peak load and adapt elastic demand to fluctuating generations. In this paper, we consider households that operate different appliances including PHEVs and batteries and propose a demand response approach based on u...
{ "abstract": "THE first appearance of Hipparion in land mammal populations of the northern hemisphere is one of the best documented biochronological events of the Neogene: the genus appeared first in the Mediterranean world about 12.5 Myr ago1. In France2 its first appearance was during the Middle–Upper ‘Helvetian’ ...
{ "abstract": "Thanks to recent palaeontological surveys in the Miocene of southern \nAfrica, it has become evident that, like the endemic plants of the \nCape Floristic Region, there are numerous lineages of animals that \noriginated in southern Africa during the Neogene. The spread of \nsome of the plants and many ...
{ "abstract": "Honeywell has been developing a 50-kW net proton exchange membrane (PEM) fuel cell stack system for transportation applications. The stack system is comprised of a PEM fuel cell stack and supporting gas, thermal and water management subsystems and is capable of integration with a number of fuel process...
{ "abstract": "Holstein is one among the dairy cattle which provide higher milk yields than most other cattle breeds. Lack of high-accuracy, reliable methods for early detection of cattle pregnancy reduces overall productivity and constitutes a high economic burden to the dairy industry. The circulating microRNAs (mi...
{ "abstract": "MicroRNA (miRNA) are found in numerous biofluids including blood and are considered a new class of biomarkers. The data presented here are related to the research article entitled “Profiling and identification of pregnancy-associated circulating microRNAs in dairy cattle” (Markkandan et al. 2018). In t...
{ "abstract": "UNLABELLED\nRSVSim is a tool for the simulation of deletions, insertions, inversions, tandem duplications and translocations of various sizes in any genome available as FASTA-file or data package in R. The structural variations can be generated randomly, based on user-supplied genomic coordinates or as...
{ "abstract": "PURPOSE\nThis study examined the growth-promoting effect of epidermal growth factor (EGF) on rabbit lens epithelial cells and the distribution of EGF receptors in these cells.\n\n\nMETHODS\nRabbit lens epithelial cells were cultured in TC-199 medium containing 0.5% fetal bovine serum and EGF for 1 to 5...
{ "abstract": "Epidermal growth factor (EGF) is a polypeptide that stimulates the growth of various tissues, including the cornea. The presence of EGF in tears from normal volunteers and in aqueous humor from cataract patients was investigated via human EGF (hEGF)-specific radioimmunoassay. Immunoreactive hEGF was fo...
{ "abstract": "Quiescent BALB/c 3T3 cells exposed briefly to a platelet-derived growth factor (PDGF) become \"competent\" to replicate their DNA but do not \"progress\" into S phase unless incubated with growth factors contained in platelet-poor plasma. Plasma from hypophysectomized rats is deficient in progression a...
{ "abstract": "The possibilities of structure elucidation of nucleic acid degradation products and of sequencing of oligonucleotides are discussed.", "corpus_id": 753909, "title": "Mass spectroscopic investigation of nucleic acid degradation products" }
{ "abstract": "Nucleic acids play key roles in the storage and processing of genetic information, as well as in the regulation of cellular processes. Consequently, they represent attractive targets for drugs against gene-related diseases. On the other hand, synthetic oligonucleotide analogues have found application a...
{ "abstract": "The methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase (MeTr) from Clostridium thermoaceticum catalyzes transfer of the N5-methyl group from (6S)-methyltetrahydrofolate (CH3-H4folate) to the cobalt center of a corrinoid/iron-sulfur protein (CFeSP), forming methylcob(III)amide and H4...
{ "abstract": "Abstract Background: Severe neonatal opioid withdrawal syndrome (NOWS) cannot be predicted. Placental aromatase metabolizes both methadone and buprenorphine and may contribute to the severity of NOWS. Objectives: To determine whether placental aromatase mRNA expression differs in methadone- or buprenor...
{ "abstract": "Abstract Opioid drugs are analgesics increasingly being prescribed to control pain associated with a wide range of causes. Usage of pregnant women has dramatically increased in the past decades. Neonates born to these women are at risk for neonatal abstinence syndrome (also referred to as neonatal opio...
{ "abstract": "ABSTRACT Although previous studies suggest that greenhouse gas (GHG) emissions from reservoir sediment exposed to the atmosphere during drought may be substantial, this process has not been rigorously quantified. Here we determined carbon dioxide (CO2) and methane (CH4) emissions from sediment cores ex...
{ "abstract": "The recording of total lactation yield for individual cows can be timeconsuming and costly. Periodic sampling at intervals throughout lactation offers an acceptable alternative, and a single day's production can be made to furnish a useful guide, by using an equation relating total to daily production....
{ "abstract": "Abstract First lactations of 397 cows with varying percentages of Holstein and Guernsey breeding provided a means of studying genetic and environmental effects on coefficients of the lactation curve y=an b e –cn (1 + u sin(x) + v cos(x)), where a, b, c, u, and v are coefficients to be estimated; e is t...
{ "abstract": "Summary Regression factors for extending part lactation milk records are developed from the within herd analysis of age-at-calving and season-of-calving corrected monthly test-day records of 9,036 Holstein cows in 374 herds in five New York counties. The best single months for estimating a complete lac...
{ "abstract": "In this paper, we propose and empirically validate a suite of hotspot patterns: recurring architecture problems that occur in most complex systems and incur high maintenance costs. In particular, we introduce two novel hotspot patterns, Unstable Interface and Implicit Cross-module Dependency. These pat...
{ "abstract": "Technical Debt is a term used to classify non-optimal solutions during software development. These solutions cause several maintenance problems and hence they should be avoided or at least documented. Although there are a considered number of studies that focus on the identification of Technical Debt, ...
{ "abstract": "For mechanical structural design, topology optimization is often utilized. During this process, a topologically optimized model must be converted into a parametric CAD solid model. The key point of conversion is that a discretized shape of a topologically optimized model must be smoothed, but features ...
{ "abstract": "Fisheries managers have long relied on non-native fish to improve, sustain, or create recreational fishing opportunities, often without adequate consideration of potentially negative ecological consequences. There is growing advocacy for using the precautionary approach to avoid potentially serious or ...
{ "abstract": "Abstract There is growing concern that predation by juvenile (ages 1–3) Striped Bass Morone saxatilis may negatively affect the population dynamics of Delta Smelt Hypomesus transpacificus, an imperiled species listed as threatened under the U.S. Endangered Species Act and endangered under the state of ...
{ "abstract": "This study evaluates the perspectives of urban mining in the framework of the circular economy (CE) and starts with a brief analysis of the size of global and urban metabolism and the role that plays materials and waste streams such as construction and demolition waste (C&DW) and waste from electronic ...
{ "abstract": "Background Cancer-related fatigue (CRF) reduces head and neck cancer (HNC) survival rates and is the most common, severe, and distressing symptom negatively impacting activities of daily living (ADLs) dependence among HNC patients. These patients remain physically inactive after their cancer treatment,...
{ "abstract": "Advanced and recurrent head and neck malignancies contribute to significant mortality and morbidity for patients. Due to difficulty in physical examination, cancers in the oral cavity, oropharynx, and larynx are especially likely to go undetected in their earlier stages. For this reason, head and neck ...
{ "abstract": "Teplizumab was recently shown to be the first-ever drug to prevent or delay type 1 diabetes mellitus onset in at-risk individuals, especially those with certain genetic and antibody characteristics. However, its potentially high price may pose challenges for coverage and reimbursement for payers and po...
{ "abstract": "This case report describes the Indirect Pulp Treatment (IPT) of deep caries lesion in a permanent molar. A 16-year-old male patient reported discomfort associated with thermal stimulation on the permanent mandibular left first molar. The radiographs revealed a deep distal caries lesion, very close to t...
{ "abstract": "Occlusar carious lesions from human molars, preserved in continuous humidity after extraction, were removed using conventional clinical techniques. Bacteriological samples were taken after rinsing the cavity with water only, after experimentally infecting the cavity and after treating uninfected caviti...
{ "abstract": "OBJECTIVE\nThe Institute of Medicine (IOM) and the Presidential Advisory Commission on Consumer Protection and Quality in the Healthcare Industry have both recently highlighted healthcare errors as a serious public health problem. An in-depth review of the issue was conducted by the National Quality Fo...
{ "abstract": "The extended Kalman filter (EKF) has been an important tool for state estimation of nonlinear systems since its introduction. However, the EKF does not possess the same optimality properties as the Kalman filter, and may perform poorly. By viewing the EKF as an optimization problem it is possible to, i...
{ "abstract": "The extended Kalman filter (EKF) is probably the most widely used estimation algorithm for nonlinear systems. However, more than 35 years of experience in the estimation community has shown that is difficult to implement, difficult to tune, and only reliable for systems that are almost linear on the ti...
{ "abstract": "The deterministic robust estimation problem is formulated in the discrete-time case as a zero-sum two person difference game, in which a statistician plays against nature. The statistician tries to estimate a linear combination of the states of an uncertain linear system, which is driven by nature. Sad...
{ "abstract": "Magnetic resonance imaging (MRI) at ultra-high fields (UHF), such as 7 T, provides an enhanced signal-to-noise ratio and has led to unprecedented high-resolution anatomic images and brain activation maps. Although a variety of radio frequency (RF) coil architectures have been developed for imaging at U...
{ "abstract": "High-field magnetic resonance imaging (HF-MRI) brings superior imaging with high contrast and signal-to-noise ratio (SNR). For scanning systems higher than 3.0 T and Larmor frequencies above 128 MHz, wavelength and higher tissue conductivity can cause distortion of the electromagnetic fields, leading t...
{ "abstract": "Abstract New molecular structural data is presented for a cyanide terminated oligomer of polytetrafluoroethene. The target molecule, CF3–(CF2)6–CN, has been seeded within a pulsed supersonic expansion of argon. The result of this action is to cool the species to rotational temperatures below 4 K. Withi...
{ "abstract": "A low power successive approximation analog-to-digital converter is presented operating at 1.2 V supply. The circuit has been designed in a 0.13 μm standard CMOS technology. The power consumption while converting is 13 μW, and in standby mode the power is reduced to 5.8 μW. The resolution is programmab...
{ "abstract": "Personalized and pervasive healthcare help seamlessly integrate healthcare and wellness into people’s daily life, independent of time and space. With the developments in biomedical sensing technolo ...", "corpus_id": 12675489, "title": "Hybrid Integration of Active Bio-signal Cable with Intelligent...
{ "abstract": "Currently, flat slabs become one of the widely used structures due to its architectural benefits such as uncomplicated formwork, flexibility and minimum construction time. However, these structures are relatively weak to resist the punching shear due to a considerable lowering in stiffness induced from...
{ "abstract": "In weakest link models the failure of a single microscopic element of a brittle material causes the failure of an entire macroscopic specimen, just as a chain fails if one link fails. Pristine samples of glass, such as optical communications fiber, approach their ideal strength, and their brittle tensi...
{ "abstract": "An analysis has been made of the tensile strength statistics of two silica fibers with quite different degrees of diameter uniformity. It has been found that the coefficient of variation in diameter (νd) is equal to that in minimum diameter (νd,min) and that the measured coefficient of variation in bre...
{ "abstract": "Objectives: To investigate trends in notification rates of Chlamydia trachomatis in Tasmania, Australia, by population sub‐groups, from 1 January 2001 to 31 December 2007.", "corpus_id": 20689444, "score": 0, "title": "Chlamydia trachomatis in Tasmania 2001–2007: rising notification trends" }
{ "abstract": "Oral squamous cell carcinoma (OSCC) is a world health problem with approximately 50% of patients having a 5-year survival rate. A change in the demographics of the disease is now being recognised, particularly in Europe, where it is increasingly being seen in young males. While a variety of risk factor...
{ "abstract": "BACKGROUND\nThis article examines differences and similarities in adolescent tobacco use among Member States of the Health Ministers' Council for the Gulf Cooperation Council (HMC/GCC) using Global Youth Tobacco Survey (GYTS) data.\n\n\nMETHODS\nNationally representative samples of students in grades a...
{ "abstract": "Forty‐six samples of oral squamous cell carcinoma (OSCC) were evaluated for the prevalence of Epstein–Barr virus (EBV) infection by the polymerase chain reaction (PCR), Southern blot hybridization, and in situ hybridization (ISH). EBV DNA was detected in 7 (15·2 per cent) out of 46 samples by a combina...
{ "abstract": "BACKGROUND\nArgininosuccinate synthetase deficiency (citrullinemia type 1) is a rare autosomal recessive disorder of the urea cycle characterized by elevated concentrations of citrulline, ammonia, and orotic acid, manifesting with acute hyperammonemic crises, usually early in life, with concurrent neur...
{ "abstract": "Over the past decade, the ASS1 and SLC25A13 genes, which are responsible for citrullinemia types I and II, have been identified, and numerous mutations in these genes have been reported. The clinical manifestations of citrullinemia are quite heterogeneous, and most studies have reported mutations in a ...
{ "abstract": "SINCE the demonstration of immunity to animal tumours1 evidence has accumulated2 indicating tumour specific antigens and corresponding antibodies in human malignant disease2–10. In malignant melanoma, antibodies have been detected only in patients with early or localized tumours11,12. After progression...
{ "abstract": "The unsteady wake of an EPPLER 361 airfoil in pitching motion has been investigated in a subsonic wind tunnel by hot-wire anemometry. The airfoil was given the pitching motion about the one-quarter chord axis at reduced frequency of 0182. Streamwise mean velocity profiles (wake profiles) were investiga...
{ "abstract": "Nomenclature c = chord CD =drag coefficient, D/qA CL =lift coefficient, L/qa CP = pressure coefficient, P-PW /q CM = pitching-moment coefficient, M/qA D =drag, Ib k = reduced frequency, wc/2U L =lift, Ib M =Mach number; pitching moment, ft-lb P = pressure, lb/in. q = dynamic pressure, 1 /2p U R, Re, Re...
{ "abstract": "Heat sources on rectangular plate with convective cooling at both upper and lower surfaces are common heat transfer application case in electronic packaging. In this paper, in order to find the analytical solution for this problem, a thermal resistances network model was established based on heat flux ...
{ "abstract": "Objectives: To estimate the incidence of diabetes, acute myocardial infarction (AMI), and stroke; and to determine factors associated with diabetes, AMI, and stroke incidence among patients previously treated for tuberculosis (TB) disease. Methods: A retrospective cohort study was conducted among non-p...
{ "abstract": "\n Tuberculosis (TB) is the leading cause of infectious mortality in the world, affecting mainly developing countries (DC), while diabetes (DM) is one of the most prevalent chronic diseases.This review analyzes the fact that diabetes is currently an important risk factor for developing TB, also present...
{ "abstract": "How do parents of children with psychiatric co-morbidities perceive their children’s use of psychiatric medications? To learn more, the Parent/Professional Advocacy League of Massachusetts (PAL), representing families of children with mental health needs, collaborated with researchers on a community-ba...
{ "abstract": "Consider the following experimental situations. In the first, subjects are shown a list of familiar words and are instructed to carefully study each of them. After performing a variety of unrelated tasks for several minutes, they are told to think back to the study list and recall as many of the presen...
{ "abstract": "The priming of patterns was examined in normal control subjects (NCS) and in the amnesic patient H.M., whose anterograde amnesia followed bilateral medial temporal-lobe excision 33 years earlier. Despite H.M.'s impaired recognition of the patterns, he demonstrated a pattern priming effect equivalent in...
{ "abstract": "Abstract : Cavities, or rectangular cutouts, exposed to fluid flow can produce an intense aero-acoustic environment. Past experience has shown that severe fluctuating pressures exist in open aircraft weapon bays under certain flight conditions. The aircraft designer must be able to predict the fluctuat...
{ "abstract": "ObjectiveThe aim of this study was to analyse the survival impact of primary tumor nodal status (N0/N+) in patients with resectable colorectal liver metastases (CLM), and to determine the value of circulating and disseminated tumor cells (CTCs/DTCs) in this setting.MethodsIn this prospective study of p...
{ "abstract": "PurposeIn patients with a high life expectancy at the time of surgery for colorectal cancer (CRC), the long-term outcome may be influenced by factors other than their cancer. We aimed to investigate the long-term outcome and cause of death beyond a 5-year surveillance programme.MethodsWe evaluated the ...
{ "abstract": "AbstracPharmacological treatment for overactive bladder has centred around the interruption of the detrusor activity that is central to urge and incontinence symptoms. The majority of patients with this disorder are treated with antimuscarinic agents. These drugs have been demonstrated to improve urgen...
{ "abstract": "This argument was made by a government attorney, Mr. Matanoski, during the trial of Cedillo v. Secretary of Health and Human Services. The Cedillo case is the first under the National Vaccine Injury Compensation Program to test a link between a standard childhood vaccine and autism spectrum disorder. M...
{ "abstract": "On February 22, 2011, in the case of Bruesewitz v Wyeth ,1 the US Supreme Court preserved the crucial role of the National Childhood Vaccine Injury Act (NCVIA) in ensuring the continuing availability of children's vaccines in the United States. Although at first glance the Bruesewitz case may seem to b...
{ "abstract": "Preface and Acknowledgments List of Abbreviations List of Photographs Timeline of Historical Events Introduction: Ghana in Perspective Precolonial States and Societies Colonial Rule Politics and Protest in the Model Colony The Model Colony at War and the Aftermath The Convention People's Party and the ...
{ "abstract": "As a convenience, let us agree to call an infinite sequence Xn X1, X2, X3, * * of independent random variables, a renewal sequence, and when all the random variables are identically distributed let us call {Xn} a renewal process. If all the random variables are nonnegative let us say {Xn} is a positive...
{ "abstract": "If oo < m < 0 then the limits given above should be interchanged. In the case where PI{X <0) = 0 the above theorem is deducible from results of Kolmogorov [1] and was proved very expeditiously by Erdts, Feller, and Pollard [2]. In the case m 5 i o? , the theorem can be proved by a different method deve...
{ "abstract": "Suppose that there are a number of independent sources at each of which events occur from time to time. The intervals between successive events at any one source are assumed to be independent random veriables all with the same distribution, so that each source constitutes a renewal process of a familia...
{ "abstract": ".......................................................................................................................................... ii
 Preface ............................................................................................................................................ iv
 Table o...
{ "abstract": "How can art, specifically photography, illustrate the limitations of vision? What do those limits reveal about perception and knowing? To explore these questions two distinct mechanisms need to be discussed in relation to creative practice, Paul Virilio’s augmenting lens that forever changes the photog...
{ "abstract": "Constellation and Classification * The Angle and the Editing * The Urgency of the Present and the Redemption of the Past * History and Recall * Video as a Way of Telling the Story of Cinema * Only Cinema can Tell its Own History * Quoting and Editing * History/ies of Cinema * History and Archaeology * ...
{ "abstract": "A constant challenge of current spatial information systems is the retrieval of spatial configurations. This paper describes a new approach to retrieving spatial information whose novelty lies in using a content measure of topological relations to search and index spatial configurations. This approach ...
{ "abstract": "This paper derives and compares two strategies for minimizing topological constraints in a query expressed by a visual example: (1) elimination of topological relations that are implied uniquely by composition and (2) restriction to topological relations that relate near-neighbor objects, as determined...
{ "abstract": "Abstract: There is a necessary requirement to provide precise dosimetry measurements for radiotherapy and radiobiological studies in the proton beams. The most common practice nowadays to obtain the dose distribution is the use of ionization chambers. However, for many needs, it is also required to est...
{ "abstract": "In [5], a new incremental cascade network architecture has been presented. This paper discusses the properties of such cascade networks and investigates their generalization abilities under the particular constraint of small data sets. The evaluation is done for cascade networks consisting of local lin...
{ "abstract": "A number of techniques exist with which neural network architectures such as multilayer perceptrons and radial basis function networks can be trained. These include backpropagation, k-means clustering and evolutionary algorithms. The latter method is particularly useful as it is able to avoid local opt...
{ "abstract": "A mass spectrometric-based procedure for anthocyanin profiling was set up to distinguish authentic Vitis vinifera from hybrid red grapevine cultivars. 3-O-Monoglucoside and the related acetyl-, p-coumaryl- and caffeoyl-monoglucoside anthocyanins occurred only in Vitis vinifera, whereas 3,5-O-diglucosid...
{ "abstract": "A two-parameter quantum deformation of the affine Lie superalgebra osp(2|2)(2) is introduced and studied in some detail. This algebra is the first example associated with nonsimply laced and twisted root systems of a quantum current algebra with the structure of a so-called infinite Hopf family of (sup...
{ "abstract": "Elliptic current algebras for arbitrary simply laced finite-dimensional Lie algebra g are defined and their co-algebraic structures are studied. Putting the algebras with different deformation parameters together, we establish a structure of an infinite Hopf family of algebras with a Drinfeld-like co-m...
{ "abstract": "An output feedback controller is developed for the lower triangular nonlinear system within the frame work of nonlinear gap metric. The controller designed is able to restrain both measurement disturbance and input disturbance. Furthermore, there exists a non-zero robust margin of plant perturbations."...
{ "abstract": "This paper first defines a novel spatial-temporal coverage metric, $k$ -depth coverage, for mobile crowdsensing (MCS) problems. This metric considers both the fraction of subareas covered by sensor readings and the number of sensor readings collected in each covered subarea. Then iCrowd , a generic MCS...
{ "abstract": "Many cities suffer from noise pollution, which compromises people's working efficiency and even mental health. New York City (NYC) has opened a platform, entitled 311, to allow people to complain about the city's issues by using a mobile app or making a phone call; noise is the third largest category o...
{ "abstract": "The usage of filter techniques for position estimation for safety-relevant purposes is an extensive field of research. Depending on the needed application for the Global Navigation Satellite System (GNSS) the state estimation can be achieved by several techniques. State estimation by means of Kalman Fi...
{ "abstract": "Automatic and accurate Gleason grading of histopathology tissue slides is crucial for prostate cancer diagnosis, treatment, and prognosis. Usually, histopathology tissue slides from different institutions show heterogeneous appearances because of different tissue preparation and staining procedures, th...
{ "abstract": "Tumor specimens contain a variety of healthy cells as well as cancerous cells, and this heterogeneity underlies resistance to various cancer therapies. But this problem has not been thoroughly investigated until recently. Meanwhile, technological breakthroughs in imaging have led to an explosion of mol...
{ "abstract": "Recognizing and manipulating objects is an important task for mobile robots performing useful services in everyday environments. While existing techniques for object recognition related to manipulation provide very good results even for noisy and incomplete data, they are typically trained using data g...
{ "abstract": "Overhearing can be seen as an instance of active learning, and overheard speech provides an increasingly viable source of linguistic input across development. However, previous studies of overhearing have often tested learning from simplified, pedagogic, adult-directed speech. This study extends previo...
{ "abstract": "Joint attention - parents' and children's coordinated attention to each other and to a third object or event - is believed to play a causal and critical role in early word learning. However, joint attention, as conventionally defined and measured, relies only on overt indicators of attention, is studie...
{ "abstract": "The double scroll attractor has been experimentally observed from an extremely simple circuit using an op amp. The purpose of this brief note is to give an alternate realization of the circuit using only two transistors as the active elements.", "corpus_id": 59109052, "score": 1, "title": "Double...
{ "abstract": "The semiconductor manufacturing industry has a large-volume multistage manufacturing system. To insure the high stability and the production yield on-line a reliable wafer monitoring is required. The approach, called Virtual Metrology (VM) is defined as the prediction of metrology variables (either mea...
{ "abstract": "Virtual metrology (VM) is a novel technology to predict wafer performance from tool slate variables. Virtual metrology can enable wafer to wafer control without additional real metrology.", "corpus_id": 33319160, "title": "Virtual metrology: a solution for wafer to wafer advanced process control" }
{ "abstract": "A source code for binary strings, admitting a simple and fast hardware implementation, is described. The code is an arithmetic code, and it is capable of encoding strings modeled by stationary or nonstationary sources alike without use of alphabet extension. In particular, in the case with a stationary...
{ "abstract": "Abstract In the present study, five configurations of integrated system are introduced and comprehensive thermodynamic modeling and analysis for different arrangements are carried out. An organic Rankine flash cycle (ORFC) and a thermoelectric generator (TEG) are integrated with a real city gate statio...
{ "abstract": "The use of biomass cook stoves is widespread in the rural communities of developing countries. It is important to improve the efficiency of these stoves in order to reduce the global warming contribution. An improved biomass fired stove has been developed in our laboratory and a prototype has been buil...
{ "abstract": "A study of how joint wear affects the kinematics of a simple slider-crank mechanism and in turn how change in kinematics of the mechanism affects the joint wear is presented. The coupling between joint wear and system kinematics is modeled by integrating a wear prediction process, built upon a widely u...
{ "abstract": "In this paper, the authors present an integrated model based on Unified Theory of Acceptance and Use of Technology UTAUT, trust and citizen satisfaction, to explore the factors which influence the adoption of e-government services in Delhi India. The findings indicate that effort expectancy, performanc...
{ "abstract": "This paper profiles the research activities that have been published on e-government adoption in the context of South Asian Association for Regional Cooperation (SAARC) countries. Our analysis includes variables such as the years of publication, journals most often publishing papers on e-government ado...
{ "abstract": "The paper examines the questions of which fiscal (public expenditure and taxation) options work in terms of poverty reduction, and how they can be made implementable in practice. The point of departure is that although the poor, acting on their own, are politically weak, nonetheless there are ways in w...
{ "abstract": "Part I: Proteins.- Amino Acids.- Protein Structure.- Proteins in the Lab.- Part II: Enzymes.- Enzymes are Biocatalysts.- Enzyme Kinetics and Mechanism.- Inhibition and Inactivation of Enzymes.- Haemyoglobin and Myoglobin: Cooperativity.- Enzyme Kinetics: Special Cases.- The Flow of Metabolites through ...
{ "abstract": "In recent years, great efforts have focused on the exploration and fabrication of protein nanoconjugates due to potential applications in many fields including bioanalytical science, biosensors, biocatalysis, biofuel cells and bio-based nanodevices. An important aspect of our understanding of protein n...
{ "abstract": "The importance of membrane-based compartmentalization in eukaryotic cell function has become broadly appreciated, and a number of studies indicate that these eukaryotic cell membranes contain coexisting liquid-ordered (L(o)) and liquid-disordered (L(d)) lipid domains. However, the current evidence for ...
{ "abstract": "This study discusses the effects of the Big Five personality traits, namely extraversion, openness, agreeableness, consciousness, and neuroticism, on customer participation in tourism service. Moreover, it verifies the relationship between customer participation, functional value, emotional value and c...
{ "abstract": null, "corpus_id": 153992756, "title": "Authenticity, involvement, and image: evaluating tourist experiences at historic districts." }
{ "abstract": "Article history: Received October 20, 2015 Received in revised format April 28, 2016 Accepted May 18 2016 Available online May 2", "corpus_id": 54790206, "score": -1, "title": "An investigation into the determinants of customer satisfaction" }
{ "abstract": "Syntheses of (+/-)trans- and (+/-)cis-2-aminocyclohexane sulfonic acid (TAHS and CAHS) and (+/-)trans-2-aminocyclopentane sulfonic acid (TAPS) were achieved. In solution, the preferred conformations of TAHS and CAHS have been determined by high field NMR to be diequatorial and equatorial (sulfonic acid...
{ "abstract": "Abstract: The effects of ATP and taurine on the kinetics of calcium uptake in rat retinal membrane preparations were determined. ATP increased calcium uptake at low calcium ion concentrations. Addition of ATP plus taurine further increased calcium uptake. Cooperative relationships were observed for cal...
{ "abstract": "Psychiatric interviews were conducted with 55 male Army HIV+ patients. These soldiers were diagnosed in an early stage of HIV, and were not clinically demented. Sixty-four percent were given diagnoses of a depressive disorder by a psychiatrist, while 42% self-reported depression. Fifty-five percent had...
{ "abstract": "An interpretation of previous and recent observation on calcium salt crystallization and calcium stone formation provide the basis for formulation of a hypothetical series of events leading to calcium oxalate (CaOx) stone formation in the urinary tract. The various steps comprise a primary precipitatio...
{ "abstract": "Renal stone disease is a frequent condition, causing a huge burden on health care systems globally. Calcium-based calculi account for around 75% of renal stone disease and the incidence of these calculi is increasing, suggesting environmental and dietary factors are acting upon a preexisting genetic ba...
{ "abstract": "Although nanozinc oxide (nano-ZnO) is applied widely in photocatalysts and gas sensors and in biological fields, it can cause serious oxidative stress and DNA damage to mammalian cells. Our aim in this study was to reduce the cytotoxicity of nano-ZnO by coating it with a TiO(2) layer. We used a sol-gel...
{ "abstract": "BackgroundThe highly pathogenic H5N1 is a major avian pathogen that intensively affects the poultry industry in Egypt even in spite of the adoption of vaccination strategy. Antigenic drift is among the strategies the influenza virus uses to escape the immune system that might develop due to the pressur...
{ "abstract": "H5 highly pathogenic avian influenza (HPAI) viruses have spread worldwide, and antigenic variants of different clades have been selected. In this study, the national stockpiled vaccine prepared from A/duck/Hokkaido/Vac-1/2004 (H5N1) strain was evaluated for the protective efficacy against H5N8 HPAI vir...
{ "abstract": "A novel application of neural network approach to protection of transmission line is demonstrated in this paper. Different system faults on a protected transmission line should be detected and classified rapidly and correctly. This paper presents the use of neural networks as a protective relaying patt...
{ "abstract": "Pulses at 780 nm from a femtosecond optical parametric oscillator and its Ti:sapphire pump laser were phase-locked as a prerequisite to coherent synthesis at different wavelengths. Coherence was demonstrated using spectral interferometry and interferometric cross-correlation.", "corpus_id": 1536789, ...
{ "abstract": "We achieved phase-coherent multicolor femtosecond pulse generation by optical phase locking among the pump and its subharmonic signal and idler pulses in an optical parametric oscillator. The ability for coherent superposition of the multicolor pulses is demonstrated in a time-domain measurement. Clear...
{ "abstract": "This paper, based on the gravity model of tourism demand, studies the factors to the travel to the neighbor areas with the example of Hong Kong tourists to Macau, analyzing the drawing forces such as promotion activities of Macau’s Special Administrative Region government and the tourism industry, cons...
{ "abstract": "If two closed Jordan curves in the plane have precisely one point in common, then it is called a touching point. All other intersection points are called crossing points. The main result of this paper is a Crossing Lemma for closed curves: In any family of n pairwise intersecting simple closed curves i...
{ "abstract": "Abstract Given n continuous open curves in the plane, we say that a pair is touching if they have finitely many interior points in common and at these points the first curve does not get from one side of the second curve to its other side. Otherwise, if the two curves intersect, they are said to form a...
{ "abstract": "The definition of the class NP (Coo71, Lev73) highlights the problem of verification of proofs as one of central interest to theoretical computer science. Recent efforts have shown that the efficiency of the verification can be greatly improved by allowing the verifier access to random bits and accepti...
{ "abstract": "The electrical behavior of small single frog atrial trabeculae in the double sucrose gap has been investigated. The currents injected during voltage clamp experiments did not behave as predicted from the assumption of spatial uniformity of the voltage across a Hodgkin-Huxley membrane. Much of the diffe...
{ "abstract": "With the voltage clamp technique it has been found that the membrane of the squid giant nerve fibre shows a sequence of specific changes in sodium and potassium conductances when the membrane is depolarized (Hodgkin & Huxley, 1952a-d; Hodgkin, Huxley & Katz, 1952). A step depolarization is associated w...
{ "abstract": "The path to Clinical Genomics is punctuated by our understanding of what types of DNA structural and sequence variation contribute to disease, the many technical challenges to detect such variation genome-wide, and the initial struggles to interpret personal genome variation in the context of disease. ...
{ "abstract": "The concept of political consumerism identifies instances when people evaluate and choose producers and products because they want to change ethically, environmentally, or politically objectionable institutional or market practices. Practices within political consumerism are informed by attitudes and v...
{ "abstract": "International legal instruments such as the Nagoya Protocol on Access to Genetic Resources and the Fair and Equitable Sharing of Benefits Arising from their Utilization to the Convention on Biological Diversity (“Nagoya Protocol”) and the International Treaty on Plant Genetic Resources for Food and Agr...
{ "abstract": "This paper adds a new introduction to the previously published update of our 2007 compilation of Bush 43 Administration signing statements that objected on constitutional grounds to one or more provisions of the laws President Bush was signing. It offers what is now a complete compilation for both the ...
{ "abstract": "Structural motifs encapsulate local sequence-structure-function relationships characteristic of related proteins, enabling the prediction of functional characteristics of new proteins, providing molecular-level insights into how those functions are performed, and supporting the development of variants ...
{ "abstract": "Coupling graphs are newly introduced in this paper to meet many application needs particularly in the field of bioinformatics. A coupling graph is a two-layer graph complex, in which each node from one layer of the graph complex has at least one connection with the nodes in the other layer, and vice ve...
{ "abstract": "SummaryThe authors describe the ultrastructure of the labial gland system in imported fire ant larvae, Solenopsis invicta Buren and present an enzyme analysis of enzymes in labial-gland secretions and midgut contents. The tubes of the labial gland produce and secrete a proteinaceous substance rich in d...
{ "abstract": "This paper presents a qualitative evaluation of a method for building information systems engineering processes. It includes the description of the evaluated method, the profiles of the selected subjects and the set up protocol. We also describe the results that allowed us to improve the method.", "c...
{ "abstract": "L'ingenierie des systemes d'information propose de nombreuses methodes et modeles produit et processus pour concevoir efficacement des systemes d'information. Cependant, les modeles de processus definis ne correspondent pas forcement aux contraintes et specificites des organisations. De plus, different...
{ "abstract": "From the 1980s, insurance activities have been developed around the world. In the industrial countries, insurance plays a key role in economic stability conditions. In developing countries, social and economic advantages of insurance have been recognized and insurance operations have been developed gra...
{ "abstract": "Murine neuroblastoma cell line Neuro-2A cells and rat brain astrocytes showed a dose-dependent increase in intracellular Ca2+ in response to bradykinin, when assessed by a single cell image analyzing system. The Ca2+ increase in Neuro-2A cells by bradykinin was also examined by a suspension fluorescent...
{ "abstract": "In response to bradykinin, phosphorylated MAP kinases (ERK‐1 and ERK‐2) were abundantly increased in HEK 293 cells, which overexpress the rat B2 kinin receptor. In a similar way des‐Arg9‐bradykinin stimulation of B1 kinin receptor‐overexpressing HEK 293 cells caused activation of the same species of MA...
{ "abstract": "Prodrugs are a class of drug derivatives with little or no pharmacological activity that are converted in vivo to therapeutically active compounds. The primary utility of a prodrug approach is to improve pharmaceutical properties. Because it does not alter the primary structure of the parent drug, the ...
{ "abstract": "Concrete examples of computation and implementation of cost/benefit decisions at the level of neuronal circuits are largely lacking. Such decisions are based on appetitive state, which is the integration of sensation, internal state, and memory. Value-based decisions are accessible in neuronal circuitr...
{ "abstract": "How and why did complex brain and behavior evolve? Clues emerge from comparative studies of animals with simpler morphology, nervous system, and behavioral economics. The brains of vertebrates, arthropods, and some annelids have highly derived executive structures and function that control downstream, ...
{ "abstract": "Abstract Health services are rarely highly successful in meeting the needs of people with headache disorders, who everywhere are low in the priority queue. Taking the UK as an example within Europe, this paper briefly reviews the present organisation of headache services, and proposes change. The solut...
{ "abstract": "Grid cells are space-modulated neurons with periodic firing fields. In moving animals, the multiple firing fields of an individual grid cell form a triangular pattern tiling the entire space available to the animal. Collectively, grid cells are thought to provide a context-independent metric representa...
{ "abstract": null, "corpus_id": 215083715, "title": "Cognitive Mapping Based on Conjunctive Representations of Space and Movement" }
{ "abstract": "Electroencephalogram (EEG) has widely been used to monitor subjects/patients’ mental states. Using the monitor results as feedback, neuro-feedback enables patients to learn to regulate their physiological and psychological states so that improvements in physical and psychological subjects/patients’ sta...
{ "abstract": "Despite significant recent progress, the best available visual saliency models still lag behind human performance in predicting eye fixations in free-viewing of natural scenes. Majority of models are based on low-level visual features and the importance of top-down factors has not yet been fully explor...
{ "abstract": "A visual attention system should respond placidly when common stimuli are presented, while at the same time keep alert to anomalous visual inputs. In this paper, a dynamic visual attention model based on the rarity of features is proposed. We introduce the Incremental Coding Length (ICL) to measure the...
{ "abstract": null, "corpus_id": 6510320, "score": -1, "title": "Beyond Prediction: Towards Automatic Intervention in MOOC Student Stop-out" }
{ "abstract": "e-Participation has advantages over traditional modes of public participation: independent of time and place, information can be provided and updated at reasonable costs. A broad range of citizens can be involved regardless of demographics, family or work situation, thereby broadening the basis for pub...
{ "abstract": "Abstract Since the advocacy planners of the 1960s first brought widespread public participation to the planning process, there have been innovations and improvements. However, the participation practices in the real world, with its face-to-face politics of difference and unequal power relations, are fl...
{ "abstract": "We outline concepts and an architecture underlying an electronic negotiation system. Once the participants' preferences are privately assessed, a variant of the balanced increment method is used to reach an agreement. The implications for such a system within e-democracy are described. Copyright © 2004...
{ "abstract": "We developed a sensitive and rapid real-time reverse transcription-polymerase chain reaction (RT-PCR) assay to detect influenza A H5N1 virus in clinical samples. This assay was evaluated with samples from H5N1-infected patients and demonstrated greater sensitivity and faster turnaround time than nested...
{ "abstract": "BACKGROUND\nRecent outbreaks of avian influenza A (H5N1) in poultry throughout Asia have had major economic and health repercussions. Human infections with this virus were identified in Vietnam in January 2004.\n\n\nMETHODS\nWe report the clinical features and preliminary epidemiologic findings among 1...
{ "abstract": "A series of low frequency fretting experiments have been conducted on a purpose built apparatus. The tests have used tin/lead plated contact surfaces to investigate the effect of electrical power on the process of fretting corrosion at these frequencies. The test samples comprised of a hemispherical ri...
{ "abstract": "Background: Ingested inorganic arsenic (InAs) is methylated to monomethylated (MMA) and dimethylated metabolites (DMA). Methylation may have an important role in arsenic toxicity, because the monomethylated trivalent metabolite [MMA(III)] is highly toxic. Objectives: We assessed the relationship of cre...
{ "abstract": "BACKGROUND\nInorganic arsenic has been linked to decreased kidney function through oxidative damage. Arsenic methylation is believed to be a pathway for arsenic metabolism. Lycopene is an antioxidant that reduces oxidative stress; however, the association between urinary arsenic species, plasma lycopen...
{ "abstract": "Hexavalent chromium (Cr-VI), as Na2CrO4 in an aqueous solution, was reduced rapidly ot the trivalent form (Cr-III) in the presence of glutathione, GSH (0.3-3.0 mM). Such GSH-dependent reduction Cr-VI can take place in the cytosolic space of Cr-VI-exposed cells, since GSH is found in reactive concentrat...
{ "abstract": "Two yeast strains representing a hitherto undescribed yeast species were isolated from olive oil and spoiled olive oil originating from Spain and Israel, respectively. Both strains are strong acetic acid producers, equipped with considerable tolerance to acetic acid. The cultures are not short-lived. C...
{ "abstract": "During an investigation of olive oil microbiota, three yeast strains were found to be divergent from currently classified yeast species according to the sequences of the D1/D2 domain of the gene encoding the rRNA large subunit (LSU) and the internal transcribed spacer region including the gene for 5.8S...
{ "abstract": "The luteinizing hormone beta subunit (LH-beta) gene plays a critical role in reproduction. In order to characterize and analyze the promoter region of LH-beta in sheep, a genomic library was constructed in phage lambda gt 10 and screened. A novel region of 1,224 bp upstream from the targeted LH-beta ge...
{ "abstract": "Abstract We describe an algorithm for the rapid direct solution of linear algebraic systems arising from the discretization of boundary integral equations of potential theory in two dimensions. The algorithm is combined with a scheme that adaptively rearranges the parameterization of the boundary in or...
{ "abstract": "We present an efficient high order method for dislocation dynamics simulation of vacancy-assisted dislocation climb in two dimensions. The method is based on a second kind integral equation (SKIE) formulation that represents the vacancy concentration via the sum of double layer potentials and point sou...
{ "abstract": "A set of approximations has been applied to allow the inclusion of Gaussian distributed priors for the linear parameters of the general linear model in order that the parameters may be integrated out alongside the Gaussian error noise variance, to give the model evidence and posterior distributions in ...
{ "abstract": "The most characterisitc manifestation of cataract at the biochemical level are the formation of high-molecular-weight protein aggregates and the appearance of a \"blue\" fluorescence of nontryptophan nature [4]. It has recently been shown that, besides protein aggregates formed by disulfide bonds [12],...
{ "abstract": "The phenolic antioxidant catavidan, used to treat heterozygous male Cat fraser mice for 4 months starting from the age of 2 months, inhibited cataract development in these mice significantly (Z=0.063 using the nonparametric Mann-Whitney test) after 2 months of treatment. However, the differences betwee...
{ "abstract": "Neurotensin (NT) and 24 related compounds, including fragments or analogues modified at the C-terminal end of the parent molecule, have been prepared by the solid-phase method. After purification by cation-exchange chromatography, the compounds were characterized by thin-layer chromatography, amino aci...
{ "abstract": "Implantable neuro-prosthetics have provided considerable clinical benefit to a range of neurological conditions. Optogenetics is a particular recent interest which utilizes high radiance light for photo-activation of genetically altered nerve cells. This can provide improved biocompatibility and neural...
{ "abstract": "Objective. This work presents a method to determine the surface temperature of microphotonic medical implants like LEDs. Our inventive step is to use the photonic emitter (LED) employed in an implantable device as its own sensor and develop readout circuitry to accurately determine the surface temperat...
{ "abstract": "Reactive tissue encapsulation of chronically implanted microelectrode probes can preclude long-term recording of extracellular action potentials. We investigated an intervention strategy for functionally encapsulated microelectrode sites. This method, known as \"rejuvenation,\" involved applying a +1.5...
{ "abstract": "The variation of the image quality and critical dimension (CD) uniformity due to the flare, geometrical aberrations and polarized light is studied in order to understand the implication on CD errors control. Some of the surprising phenomena, which occurring at high numerical aperture (NA), are studied ...
{ "abstract": "In this paper we report on the method of measuring the magnitude of scattered light, flare in a stepper lens and its effect on the overall process latitude. By measuring the required energy to clear large square patterns, it was possible to calculate the amount of scattered light in a lens system. When...
{ "abstract": "It is becoming increasingly clear that semiconductor manufacturers must rise to the challenge of extending optical microlithography beyond what is forecast by the current SIA roadmap. Capabilities must be developed that allow the use of conventional exposure methods beyond their designed capabilities. ...
{ "abstract": "In this letter, we propose a learning system, active decision fusion learning (ADFL), for active fusion of decisions. Each decision maker, referred to as a local decision maker, provides its suggestion in the form of a probability distribution over all possible decisions. The goal of the system is to l...
{ "abstract": "There is almost always a cost associated with acquiring training data. We consider the situation where the learner, with a fixed budget, may ‘purchase’ data during training. In particular, we examine the case where observing the value of a feature of a training example has an associated cost, and the t...
{ "abstract": "Discriminative latent-variable models are typically learned using EM or gradient-based optimization, which suffer from local optima. In this paper, we develop a new computationally efficient and provably consistent estimator for a mixture of linear regressions, a simple instance of a discriminative lat...
{ "abstract": "We demonstrate ultralow ohmic contact resistance to antimonide-based, p-channel quantum-well field-effect transistor (QW-FET) structures using a new p<sup>±</sup>-InAs/InAsSb cap structure. The incorporation of a p<sup>±</sup>-InAsSb layer enables the use of a thicker cap with lower sheet resistance, r...
{ "abstract": "Recent decades have seen an exponential increase in the functionality of electronic circuits, allowing for continuous innovation, which benefits society. This increase in functionality has been facilitated by scaling down the dimensions of the most important electronic component in modern electronics: ...
{ "abstract": "The alpha structure as well as the new beta modification of Ti(2)Se were recently characterized by electron diffraction structural analysis of nanosize crystallites. In this study, both structures are investigated by means of total energy calculations within the non-local density-functional theory in o...
{ "abstract": "Concept learning is challenging in part because the meanings of many concepts depend on their relationships to other concepts. Learning these concepts in isolation can be difficult, but we present a model that discovers entire systems of related concepts. These systems can be viewed as simple theories ...
{ "abstract": "Everyday knowledge about living things, physical objects and the beliefs and desires of other people appears to be organized into sophisticated systems that are often called intuitive theories. Two long term goals for psychological research are to understand how these theories are mentally represented,...
{ "abstract": "Feature- vs. Relation-Defined Categories: Probab(alistic)ly Not the Same Aniket Kittur (nkittur@ucla.edu) John E. Hummel (jhummel@lifesci.ucla.edu) Keith J. Holyoak (holyoak@lifesci.ucla.edu) Department of Psychology, 1285 Franz Hall University of California, Los Angeles Los Angeles, CA 90095 known abo...
{ "abstract": "We present and explore the effectiveness of sev- eral variations on the All-Moves-As-First (AMAF) heuristic in Monte-Carlo Go. Our results show that: Random play-outs provide more information about the goodness of moves made earlier in the play-out. AMAF updates are not just a way to quickly initialize...
{ "abstract": "Research on multi-robot systems has demonstrated promising results in manifold applications and domains. Still, efficiently learning an effective robot behaviors is very difficult, due to unstructured scenarios, high uncertainties, and large state dimensionality (e.g. hyper-redundant and groups of robo...
{ "abstract": "Data has become highly valuable for many of companies and organizations. With the development of advanced data science methods and computer power, extraction of intelligible knowledge using predictive models has become helpful in decision-making. In healthcare, opportunities are numerous and Machine Le...
{ "abstract": "This study investigated the effect of distraction on driving performance for drivers using a touch screen. We evaluated the influence of three secondary tasks on the primary task varying the task duration and the screen position using 16 participants whose ages ranged from the twenties to the fifties. ...
{ "abstract": "Abstract Driver assistance systems could be much more effective, if they were adaptive to the driver’s state. Following the idea of a lane-keeping assistance system, which is adaptive to the use of in-vehicle information systems (IVIS), two field experiments were conducted. The first experiment concern...
{ "abstract": "Significant advances in electronics and microcomputing during the past few decades have led to the feasibility of a functionally powerful, computer-based Advanced Traveler Information System (ATIS) as part of the automotive environment. Although these systems range in functionality, they all have the g...
{ "abstract": "A cohort of 1655 patients with Crohn's disease diagnosed during 1983 in the Uppsala health care region, Sweden, was followed up with respect to the occurrence of colorectal cancer to the end of 1984. 12 colorectal cancers were diagnosed, yielding an increased overall risk of 2.5. The relative risk was ...
{ "abstract": "As duration of inflammatory bowel disease (IBD), in particular ulcerative colitis (UC), is a major risk factor for the development of colorectal cancer (CRC), it is rational to propose a screening colonoscopy when the risk starts to increase, i.e., after 8-10 years from the onset of disease. If low-gra...
{ "abstract": "In performing colonoscopy over a 4-yr period on 112 patients with long-standing ulcerative colitis, a dysplasia-associated lesion or mass (DALM) was found in 12. This appeared as either a single polypoid mass (5 cases), a plaquelike lesion (2 cases), or multiple polyps (5 cases). In 7 of these 12 cases...
{ "abstract": "OBJECTIVE ::: To compare the morphology of the hymen in adolescent girls who have and have not had sexual intercourse involving penile-vaginal penetration. ::: ::: ::: SUBJECTS ::: Female patients aged 13 to 19 years, recruited from an urban adolescent medicine practice. ::: ::: ::: METHODS ::: Subject...
{ "abstract": "A 16-year-old girl was referred to our gynaecology service, reporting of cyclic pelvic pain and primary amenorrhoea. The medical history had begun 4 years earlier with pelvic pain getting worse over time, disturbing her studies. Physical examination revealed a mass of 14 weeks’ gravid uterus. The patie...
{ "abstract": null, "corpus_id": 28303765, "score": -1, "title": "Patient assaults on residents." }
{ "abstract": "We investigate a set of stochastic models of biodiversity, population genetics, language evolution, and opinion dynamics on a network within a common framework. Each node has a state 0<x(i)<1 with interactions specified by strengths m(ij). For any set of m(ij), we derive an approximate expression for t...
{ "abstract": "Microbiology is the science of microbes, particularly bacteria. Many bacteria are motile: they are capable of self-propulsion. Among these, a significant class execute so-called run-and-tumble motion: they follow a fairly straight path for a certain distance, then abruptly change direction before repea...
{ "abstract": "We propose a novel formulation of the firing squad synchronization problem. In this formulation we may use more than one general state and the general state to be used is determined by the boundary condition of the general. We show that the usual formulation and the new formulation yield different mini...
{ "abstract": "The metric distance obtained from the large deformation diffeomorphic metric mapping (LDDMM) algorithm is used to quantize changes in morphometry of brain structures due to neuropsychiatric diseases. For illustrative purposes we consider changes in hippocampal morphometry (shape and size) due to very m...
{ "abstract": "In this article, we use longitudinal morphometry (shape and size) measures of hippocampus in subjects with mild dementia of Alzheimer type (DAT) and nondemented controls in logistic discrimination. The morphometric measures we use are volume and metric distance measures at baseline and follow-up (two y...
{ "abstract": "OBJECTIVE: To assess vitamin E levels in the breast milk, analyzing the prematurity and the birth weight influence in α-tocopherol concentration of colostrum milk. METHODS: Cross-sectional study, in which the colostrum was collected from 93 nursing mothers in a public maternity of Natal, Rio Grande do ...
{ "abstract": "Agile based software development approach is increasingly gaining much interest among software practitioners and researchers due to its ability to produce high quality software in shorter period of time. Even though its importance has been revealed, only few studies were conducted regarding its current...
{ "abstract": "In the past few years, anecdotal evidence of mostly positive experiences with the implementation of agile development methods has emerged from case studies. We used a survey strategy, which enables data gathering from a larger sample of organizations, to learn about the factors driving the adoption and...
{ "abstract": "This paper describes a search-based generative method which creates game levels by evolving the intended sequence of player actions rather than their spatial layout. The proposed approach evolves graphs where nodes representing player actions are linked to form one or more ways in which a mission can b...
{ "abstract": "The strategy for the collection of information (i.e., data) for model development is called experimental design. Optimal design seeks to maximize the information content under constraints of time and sampling. In the system identification literature the dominant strategy has been the method of pseudo r...
{ "abstract": "Abstract Discrete-time modelling (DTM) dominates the systems engineering literature in the applications of block-oriented modelling. The discrete environment of computer-based process control systems and discrete sampling are two major reasons [1]. Also, a DTM is easier to obtain because all input chan...
{ "abstract": "This paper presents a novel approach to model the complex motion of human using a probabilistic autoregressive moving average model. The parameters of the model are adaptively tuned during the course of tracking by utilizing the main varying components of the pdf of the target’s acceleration and veloci...
{ "abstract": "Visualization is a research hotspot in Digital Earth. Available Digital Earth platforms, such as Google Earth and World Wind could only display the prebuilt tiles of geospatial data statically, due to inability to deal with massive geospatial data (especially the remotely sensed imagery) and to adapt f...
{ "abstract": "Abstract As the important infrastructures for land mapping and resource monitoring, high-resolution remote sensing satellites (HRSS) are urgently demanded for the development of China. In this article, the key technologies of the main HRSS are summarized, and these technologies include sensor design, a...
{ "abstract": "Publisher Summary Argasid ticks feed rapidly and pass through numerous moults to reach the engorged female stage. On the other hand, the feeding of ixodid ticks is characterized by the capacity of each instar to ingest large volumes of host blood and so avoid the frequent host-finding associated with a...
{ "abstract": "The ability to predict performance of students is very crucial in our present education system. We can use data mining concepts for this purpose. ID3 algorithm is one of the famous algorithms present today to generate decision trees. But this algorithm has a shortcoming that it is inclined to attribute...
{ "abstract": "Educational Data Mining (EDM) is an evolving field exploring pedagogical data by applying different machine learning techniques/tools. It can be considered as interdisciplinary research field which provides intrinsic knowledge of teaching and learning process for effective education. The main objective...
{ "abstract": "Crowdfunding is a recent financing phenomenon that is gaining wide popularity as a means for startups to raise seed funding for their companies. This paper presents our initial results at understanding this phenomenon using an exploratory data driven approach. We have developed a big data platform for ...
{ "abstract": "RATIONALE & OBJECTIVE\nMetabolically healthy obesity (obesity without any metabolic abnormality) is considered not to be associated with increased risk of morbidity and mortality. We aimed to examine and quantify the association between metabolically healthy overweight/obesity and the risk of incident ...
{ "abstract": "The prevalence of obesity is increasing worldwide and contributes to many health problems, including kidney disease. Unexpectedly, 10-30% of obese individuals are apparently not at increased risk of metabolic diseases, e.g. type 2 diabetes, cardiovascular disease and risk of renal disease. Their phenot...
{ "abstract": "The aim of this study was to examine the association between BMI categories, stratified by metabolic health status, and the risk of kidney function decline (KFD).", "corpus_id": 4405719, "score": -1, "title": "Metabolically Healthy Obesity and Risk of Kidney Function Decline" }
{ "abstract": "ABSTRACT In this study, investigation was conducted into concentrations of perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) in Chinese farmed Trachinotus ovatus between 2014 and 2015 using a modified QuEChERS (Quick, Easy, Cheap, Effective, Rugged and Safe) and ultra fast liquid chrom...
{ "abstract": "Persistent halogenated compounds (PHCs) contamination has become a major concern over the world. Here we investigated occurrence, spatial distributions, congener profiles, as well as health risks of PHCs in farmed golden pompano in China using gas chromatography/mass spectrometry (GC/MS). The concentra...
{ "abstract": "Abstract The media are crucial players in the construction of, and communication about, risk. Yet their role is often under-theorised, and sometimes misrepresented or parodied. In particular, the media are accused of routine sensationalism. Journalists are blamed for exaggerating risk, ‘whipping up hys...
{ "abstract": "Performance analysis of sub-word language modeling for under-resourced languages with rich morphology : case study on Swahili and Amharic This paper investigates the impact on ASR performance of sub-word units for two underresourced african languages with rich morphology (Amharic and Swahili). Two subw...
{ "abstract": "This paper presents two-pass speech recognition techniques to handle the out-of-vocabulary (OOV) problem in Turkish newspaper content transcription. OOV words are assumed to be replaced by acoustically ldquosimilarrdquo in-vocabulary (IV) words during decoding. Therefore, the first pass recognition lat...
{ "abstract": "This paper addresses compound splitting for Dutch in the context of broadcast news transcription. Language models were created using original text versions and text versions that were decomposed using a data-driven compound splitting algorithm. Language model performances were compared in terms of out-...
{ "abstract": "Abstract 1. 1. The study of the effects of aliphatic diamines on the thermal stability of polynucleotides has been extended to an investigation of the interaction of these cations with the helical duplexes poly-A-poly-U and poly-I-poly-C. In both instances there is stabilization which decreases in the ...
{ "abstract": "Abstract Amberlite IR-120, a polystyrene sulphonate type of cation exchanger, equilibrated with Al3+ has been used for the fractionation of DNA in conjunction with a discontinuous gradient elution procedure. This affords a quantitative and reproducible recovery of DNA in seven distinct fractions each d...
{ "abstract": "The use of gamification in education contexts is increasing at a rapid pace, particularly due to its huge potential in motivating and engaging students. This study used an online survey to define the factors that influence the adoption of education gamification in Abu Dhabi. As the results suggest, the...
{ "abstract": "An ultracompact silicon electro-optic modulator operating at 1550-nm telecom wavelengths is proposed and analyzed theoretically, which consists of a Cu-TiO(2)-Si hybrid plasmonic donut resonator evanescently coupled with a conventional Si channel waveguide. Owing to a negative thermo-optic coefficient ...
{ "abstract": "We experimentally demonstrate an ultracompact PlasMOStor, a plasmon slot waveguide field-effect modulator based on a transparent conducting oxide active region. By electrically modulating the conducting oxide material deposited into the gaps of highly confined plasmonic slot waveguides, we demonstrate ...
{ "abstract": "Aims. We study trajectories of planetesimals whose orbits decay due to gas drag in a primordial solar nebula and are perturbed by the gravity of the secondary body on an eccentric orbit whose mass ratio takes values from µ2 = 10 −7 to µ2 = 10 −3 increasing ten times at each step. Each planetesimal ulti...
{ "abstract": "Establishment of cells in tissue culture from Barrett's columnar epithelium has been difficult. The aim of this study was to develop a successful tissue culture method employing a serumfree medium for cultivation of Barrett's epithelial cells. Fragments of Barrett's mucosal tissue were explanted in a 3...
{ "abstract": "Barrett's esophagus (BE) is a metaplastic process in which the normal squamous epithelium of the distal esophagus is replaced by columnar lined epithelium. The aim was to gain more insight in the process of metaplasia and to identify which genes are specifically expressed by the epithelial cells and th...
{ "abstract": "To determine whether the transcription regulatory activities of the adenoviral E1a gene play a role in its ability to transform primary cells we have constructed an extensive series of mutations within the E1a gene. The mutants have been characterized for their ability to transactivate the adenoviral e...
{ "abstract": "In some investigations of digital crime, the question of who was at the keyboard when incriminating documents were produced can be legitimately raised. Authorship attribution can then contribute to the investigation. Authorship methods which focus on linguistic characteristics currently have accuracy r...
{ "abstract": "Stylometry is a method for identifying anonymous authors of anonymous texts by analyzing their writing style. While stylometric methods have produced impressive results in previous experiments, we wanted to explore their performance on a challenging dataset of particular interest to the security resear...
{ "abstract": "This paper presents the first work on POS tagging German Twitter data, showing that despite the noisy and often cryptic nature of the data a fine-grained analysis of POS tags on Twitter microtext is feasible. Our CRF-based tagger achieves an accuracy of around 89% when trained on LDA word clusters, fea...
{ "abstract": "C-Mannosylation is a unique form of protein glycosylation, involving the C-glycosidic attachment of a mannosyl residue to the indole moiety of Trp. In the two examples found so far, human RNase 2 and interleukin-12, only the first Trp in the recognition motif WXXW is specificallyC-mannosylated. To esta...
{ "abstract": "AbstractThe human complement hetero-trimeric C8αβγ (C8) protein assembly (~ 150 kDa) is an important component of the membrane attack complex (MAC). C8 initiates membrane penetration and coordinates MAC pore formation. Here, we charted in detail the structural micro-heterogeneity within C8, purified fr...
{ "abstract": "Although it is generally assumed that HIV transmission does not occur through casual oral contact, persistent reports in the literature and the well-documented case of the Florida dentist (Ou et al., 1992) have served to elevate concerns and interest about the possibility of oral transmission of HIV. T...
{ "abstract": "Alanine-scanning mutagenesis of transmembrane segments IS6 and IIS6 of the rat brain Nav1.2 channel α subunit identified mutations N418A in IS6 and L975A in IIS6 as causing strong positive shifts in the voltage dependence of activation. In contrast, mutations V424A in IS6 and L983A in IIS6 caused stron...
{ "abstract": "The outer vestibule of voltage-gated Na+ channels is formed by extracellular loops connecting the S5 and S6 segments of all four domains (“P-loops”), which fold back into the membrane. Classically, this structure has been implicated in the control of ion permeation and in toxin blockage. However, confo...
{ "abstract": "A new method for evaluating modulus and hardness from nanoindentation load/ displacement curves is presented. As a spherical indenter penetrates an elastoplastic half-space, the elastic displacement above the contact line is presumed to diminish in proportion to the total elastic displacement under the...
{ "abstract": "A new synthetic methodology has been developed to prepare the biologically important azepino[4,5-b]indole derivatives under Brønsted acid catalysis. The notable features of this protocol include its operational simplicity, high reaction yields and environmentally benign and mild reaction conditions.", ...
{ "abstract": "Pyrrole and indole derivatives are functionalized via a green initiative with the dimethyl malonate derived phenyl iodonium ylide 4a in the presence of a blue LED via C-H functionalization of the respective heterocycles in methanol to generate the desired compounds 5-7 in moderate to good yields. Contr...
{ "abstract": "Continuous Pharmaceutical Manufacturing (CPM) has the potential to revolutionize the pharmaceutical industry, with many expected benefits in terms of cost, efficiency, and quality. Process modeling and optimization are valuable methodologies for comparative technoeconomic evaluations: this paper pursue...
{ "abstract": "The orphan nuclear hormone receptor small heterodimer partner (SHP) regulates the expression of several genes involved in bile acid homeostasis in the liver. Because bile acid toxicity is a major source of liver injury in cholestatic disease, we explored the role of SHP in liver damage induced by commo...
{ "abstract": "The nuclear receptor LRH-1 (NR5A2) functions to regulate expression of a number of genes associated with bile acid homeostasis and other liver functions, but mechanisms that modulate its activity remain unclear. We have found that mitogenic stimuli, including treatment with phorbol myristate (PMA), inc...
{ "abstract": "Carbamylation of proteins in vivo occurs by cyanate, non-enzymatically when urea is dissociated, and by myeloperoxidase-catalyzed oxidation from thiocyanate. Carbamylation of low-density lipoprotein is suggested to enhance atherogenesis in patients with with chronic kidney disease and uremia. This thes...