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selective and membrane permeable small molecule inhibitors of nicotinamide n methyltransferase reverse high fat diet induced obesity in mice | promising anti obesity drug shrinks fat without suppressing appetite |
restoration of sensitivity in chemo resistant glioma cells by cold atmospheric plasma | cold plasma successful against brain cancer cells study suggests |
quantifying climate sensitivity and climate driven change in north american amphibian communities | climate change not main driver of amphibian decline |
paris thin a call to regulate life threatening starvation of runway models in the us fashion industry | call to regulate starvation of paris thin models |
why lifespans are more variable among blacks than among whites in the united states | why lifespans are more variable among blacks than whites in the u.s. |
therapeutic targeting of bet bromodomain proteins in castration resistant prostate cancer | new target for prostate cancer resistant to anti hormone therapies |
declining use of radiotherapy for adverse features after radical prostatectomy results from the national cancer data base | use of radiotherapy after prostate cancer surgery declining despite evidence of benefit |
risk factors for osteonecrosis of the jaws a case control study from the condor dental pbrn | experts release large studies on osteonecrosis of the jaw |
a novel noninvasive predictive epilepsy biomarker with clinical potential | animal study unveils predictive marker for epilepsy development following febrile seizure |
atrial arrhythmias after lung transplantation incidence and risk factors in lung transplant recipients | researchers shine light on common heart complication after lung transplantation |
evolutionary history resolves global organization of root functional traits | theory suggests root efficiency independence drove global spread of flora |
mortality from diseases conditions and injuries where alcohol is a necessary cause in the americas | alcohol consumption is a necessary cause of nearly deaths per year in the americas study finds |
gut and blood differ in constitutive blocks to hiv transcription suggesting tissue specific differences in the mechanisms that govern hiv latency | hiv latency differs across tissues in the body |
a complete catalogue of high quality topological materials | good news for future tech exotic topological materials are surprisingly common |
following suit using conversation cards for priority setting in pediatric weight management | conversation cards a useful tool in pediatric weight management |
a multilevel analysis of the relationship between parental migration and left behind children s macronutrient intakes in rural china | rising risk of obesity among china s left behind children |
innovative self regulation strategies to reduce weight gain in young adults | national study shows new ways to stop weight gain cut young adults obesity risk by half |
inter annual and decadal changes in teleconnections drive continental scale synchronization of tree reproduction | north atlantic oscillation synchronizes tree reproduction across europe |
comprehensive analysis of dengue virus specific responses supports an hla linked protective role for cd t cells | surprising finding could alter the face of dengue vaccine development |
envelope residue substitutions in simian human immunodeficiency viruses enhance cd binding and replication in rhesus macaques | better animal model to improve hiv vaccine development |
impact of smoking ban on passive smoke exposure in pregnant non smokers in the southeastern united states | pregnant women in nc exposed to less secondhand nicotine after smoking ban |
direct benefit of vaccinating boys along with girls against oncogenic human papillomavirus bayesian evidence synthesis | men benefit from vaccinating girls against hpv but remain at risk of some cancers |
dna methylation outliers in normal breast tissue identify field defects that are enriched in cancer | vital clues to future cancer development in normal breast tissue dna |
the social environment and suicide attempts in lesbian gay and bisexual youth | study links social environment to high attempted suicide rates among gay youth |
association of prescribed opioids with increased risk of community acquired pneumonia among patients with and without hiv | prescribed opioids raise risk of pneumonia in patients with and without hiv |
exosomes secreted by nematode parasites transfer small rnas to mammalian cells and modulate innate immunity | trojan horse tactic gives parasites edge over immune systems |
scai acc hfsa sts clinical expert consensus statement on the use of percutaneous mechanical circulatory support devices in cardiovascular care | new guidance on use of heart pumps released by leading cardiovascular societies |
human papillomavirus genotype distributions implications for vaccination and cancer screening in the united states | human papillomavirus genotype distribution in new mexico cervical cancers |
long haul optical transmission link using low noise phase sensitive amplifiers | fibre optic transmission of km made possible by ultra low noise optical amplifiers |
strategies for network gwas evaluated using classroom crowd science | classroom crowdscience students challenged to detect schizophrenia genes |
does shortening the school week impact student performance ? evidence from the four day school week | four day school week can improve academic performance study finds |
hypothalamic agrp neurons control peripheral substrate utilization and nutrient partitioning | brain neurons and diet influence onset of obesity and diabetes in mice |
retinal vessel caliber and lifelong neuropsychological functioning retinal imaging as an investigative tool for cognitive epidemiology | blood vessels in the eye linked with iq cognitive function |
maternal prenatal iron status and tissue organization in the neonatal brain | prenatal maternal iron intake shown to affect the neonatal brain |
common genetic variants and risk of brain injury after preterm birth | genes play key role in brain injury risk for premature babies |
age of first exposure to football and later life cognitive impairment in former nfl players | former nfl players who played tackle football before age at increased risk of memory thinking problems later |
detection of unamplified target genes via crispr cas immobilized on a graphene field effect transistor | crispr chip enables digital detection of dna without amplification |
immigrants at the mississippian polity of cahokia strontium isotope evidence for population movement | native american city on the mississippi was america s first melting pot |
comparison of the value of nursing work environments in hospitals across different levels of patient risk | lower surgical mortality in hospitals with best nursing care novel study shows |
broad diversity of neutralizing antibodies isolated from memory b cells in hiv infected individuals | new technology opens gateway to studying hiv specific neutralizing antibodies |
a latitudinally banded phytoplankton response to st century climate change in the southern ocean across the cmip model suite | tiny phytoplankton have big influence on climate change |
immunogenicity and reactogenicity of alternative schedules of hpv vaccine in vietnam a cluster randomized noninferiority trial | lengthening dosing schedule of hpv vaccine may provide effective option for expanding use of vaccine |
reduction of common cold symptoms by encapsulated juice powder concentrate of fruits and vegetables a randomised double blind placebo controlled trial | fruit and vegetable concentrate decreases number of days with severe cold symptoms |
life in a fishbowl prospects for the endangered devils hole pupfish cyprinodon diabolis in a changing climate | climate change puts endangered devils hole pupfish at risk of extinction |
the appropriateness of more intensive colonoscopy screening than recommended in medicare beneficiaries | older patients with limited life expectancy still receiving cancer screenings |
genome wide association study reveals multiple loci associated with primary tooth development during infancy | late baby teeth may mean more orthodontic visits genes associated with early tooth development identified |
development of amygdala functional connectivity during infancy and its relationship with year behavioral outcomes | brain circuits for successful emotional development established during infancy |
dried blood spot real time polymerase chain reaction assays to screen newborns for congenital cytomegalovirus infection | traditional heel stick test is not an effective screening tool for cmv in newborns |
remote sensing of ground deformation for monitoring groundwater management practices application to the santa clara valley during the california drought | scientists monitor silicon valley s underground water reserves from space |
a novel approach to modelling transcriptional heterogeneity identifies the oncogene candidate cbx in invasive breast carcinoma | new gene hunt reveals potential breast cancer treatment target |
repeat bleaching of a central pacific coral reef over the past six decades | study tracks severe bleaching events on a pacific coral reef over past century |
cacao polyphenols influence the regulation of apolipoprotein in hepg and caco cells | new explanation for heart healthy benefits of chocolate |
comparative genomics identifies epidermal proteins associated with the evolution of the turtle shell | similar proteins protect the skin of humans turtles |
new strategies are needed to stop overdose fatalities the case for supervised injection facilities | to reduce overdose deaths us needs to pilot the use of supervised injection facilities |
a non bipartite propensity score analysis of the effects of teacher student relationships on adolescent problem and prosocial behavior | positive teacher student relationships boost good behavior in teenagers for up to years |
cytokinin induces genome wide binding of the type b response regulator arr to regulate growth and development in arabidopsis | greater understanding of plant hormone results in stem cells that grow shoots |
body size downgrading of mammals over the late quaternary | unprecedented wave of large mammal extinctions linked to prehistoric humans |
prokaryotic diversity and biogeochemical characteristics of benthic microbial ecosystems at la brava a hypersaline lake at salar de atacama chile | microbial ecosystem at laguna la brava may contain novel microorganisms |
baby gate related injuries among children in the united states | number of children treated in u. s. emergency departments for baby gate related injuries nearly quadrupled since |
structures of archaeal dna segregation machinery reveal bacterial and eukaryotic linkages | scientists unlock secrets of a heat loving microbe |
fitness landscape of the human immunodeficiency virus envelope protein that is targeted by antibodies | big data methods learn the fitness landscape of the hiv envelope protein |
from the cover spiny frogs paini illuminate the history of the himalayan region and southeast asia | frogs evolution tracks rise of himalayas and rearrangement of southeast asia |
monoclonal antibodies for emerging infectious diseases borrowing from history | for nanomedicine cell sex matmonoclonal antibodies crucial to fighting emerging infectious diseases |
metabotropic glutamate receptor is a coreceptor for alzheimer a oligomer bound to cellular prion protein | alzheimer s missing link found promising target for new drugs |
patterned and functionalized nanofiber scaffolds in three dimensional hydrogel constructs enhance neurite outgrowth and directional control | d neural structure guided with biocompatible nanofiber scaffolds and hydrogels |
does a scientific breakthrough increase confidence in science ? news of a zika vaccine and trust in science | public trust in science spiked after media coverage of zika vaccine trial |
successful conservation of global waterbird populations depends on effective governance | political instability and weak governance lead to loss of species study finds |
perspective taking abilities in the balance between autism tendencies and psychosis proneness | perspective taking difficulties diminished when autistic and psychosis tendencies balance |
a framework to assess national level vulnerability from the perspective of food security the case of coral reef fisheries | corals and food security study shows nations at risk |
can we build an efficient response to the prescription drug abuse epidemic ? assessing the cost effectiveness of universal prevention in the prosper trial | in fight against teen prescription drug abuse home and school based programs work in combination |
potential protective effect of biphasic electrical stimulation against growth factor deprived apoptosis on olfactory bulb neural progenitor cells through the brain derived neurotrophic factor phosphatidylinositol kinase akt pathway | biphasic electrical stimulation a strategy may bring hope to spinal cord injury patients |
first trimester plasma glucose values in women without diabetes are associated with risk for congenital heart disease in offspring | higher blood sugar in early pregnancy raises baby s heart defect risk |
static dental disparity and morphological turnover in sharks across the end cretaceous mass extinction | the end cretaceous extinction unleashed modern shark diversity |
crispr enhanced engineering of therapy sensitive cancer cells for self targeting of primary and metastatic tumors | engineered cancer cells can fight primary and metastatic cancer |
the genome and development dependent transcriptomes of pyronema confluens a window into fungal evolution | gap closed in the genetic map of fungi research team sequences genome of pyronema confluens |
a single crispr cas deletion strategy that targets the majority of dmd patients restores dystrophin function in hipsc derived muscle cells | stem cell gene therapy could be key to treating duchenne muscular dystrophy |
translational control of lipogenic enzymes in the cell cycle of synchronous growing yeast cells | study finds new target for controlling cell division |
multi level proteomics identifies ct as a chemosensitivity mediator and immunotherapy target in ovarian cancer | novel biomarker found in ovarian cancer patients can predict response to therapy |
pik ca mutations enable targeting of a breast tumor dependency through mtor mediated mcl translation | common breast cancer mutation could be vulnerable to drug combination |
performance and validation of the u.s. ncdr acute kidney injury prediction model in japan | us prediction models for kidney injury following angioplasty hold up in japan |
prediction of the incidence recurrence and persistence of atopic dermatitis in adolescence a prospective cohort study | choice of career is a major risk factor for persistent neurodermatitis |
interpretation and use of frax in clinical practice | new review clarifies the use of frax in clinical practice |
direct observations of evolving subglacial drainage beneath the greenland ice sheet | evolving plumbing system beneath greenland slows ice sheet as summer progresses |
the relationship between exposure to brand specific alcohol advertising and brand specific consumption among underage drinkers united states | alcohol ads linked to teen alcohol brand choices |
dynamic illumination of spatially restricted or large brain volumes via a single tapered optical fiber | new adjustable optical microprobe for the analysis and control of deep brain regions |
influence of previous radiation exposure on pathologic features and clinical outcome in patients with thyroid cancer | radiation exposure associated with more aggressive thyroid cancer worse outcomes |
stable isotope studies reveal pathways for the incorporation of non essential amino acids in acyrthosiphon pisum pea aphids | aphids balance their diets by rebuilding plant amino acids |
prophylactic antibiotics in the prevention of infection after operative vaginal delivery anode a multicentre randomised controlled trial | preventative antibiotics after assisted childbirth almost halve maternal infection rate and reduce overall antibiotic use |
highly conductive carbon nanotube matrix accelerates developmental chloride extrusion in central nervous system neurons by increased expression of chloride transporter kcc | carbon nanotubes lower nerve damaging chloride in cells |
radiocesium in migratory aquatic game birds using contaminated u.s. department of energy reactor cooling reservoirs a long term perspective | aquatic rest stops may pose potential hazards for migratory waterfowl |
human cancer antigen globo h is a cell surface ligand for human ribonuclease | cancer discovery links experimental vaccine and biological treatment |
biomechanical consequences of running with deep core muscle weakness | study uncovers potential key to preventing back pain in runners |
chronic kidney disease of unknown cause in agricultural communities | chronic kidney disease epidemic in agricultural workers high heat toxins |
misuse of stimulant medication among college students a comprehensive review and meta analysis | one in six college students misuse adhd stimulant drugs |
neurodegeneration and functional impairments associated with glycogen synthase accumulation in a mouse model of lafora disease | link between abnormal sugar accumulation and the neuronal degeneration characteristic of lafora disease |
mutant ataxin disrupts cerebellar development in spinocerebellar ataxia type | adult onset neurodegeneration has roots in early development |
the effect of the composition of pla films and lactate release on glial and neuronal maturation and the maintenance of the neuronal progenitor niche | a step towards repairing the central nervous system |
automated whole cell patch clamp electrophysiology of neurons in vivo | robot reveals the inner workings of brain cells automated way to record electrical activity inside neurons in the living brain |
detection of zika virus using reverse transcription lamp coupled with reverse dot blot analysis in saliva | researchers adapt hiv test in developing rapid diagnostic test for zika virus |
chronic ethanol feeding increases the severity of staphylococcus aureus skin infections by altering local host defenses | restoring il may treat skin infections related to chronic alcohol consumption |