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682
Lack of FGF21 in mice leads to reduced lifespan.
[ { "doc_id": 9315213, "sentence_ids": [ 4 ], "label": "SUPPORT" } ]
[ 9315213 ]
683
Lack of FGF21 in mice slows the rate of atherosclerotic plaque formation.
[ { "doc_id": 9315213, "sentence_ids": [ 4 ], "label": "CONTRADICT" }, { "doc_id": 9315213, "sentence_ids": [ 5 ], "label": "CONTRADICT" }, { "doc_id": 9315213, "sentence_ids": [ 8 ], "label": "CONTRADICT" } ]
[ 9315213 ]
685
Lamins are associated with nuclear membrane structure maintenance.
[]
[ 4452659 ]
686
Lamins are found within the inner layer of the mitochondrial membrane of all cells.
[]
[ 4452659 ]
687
Lamins are found within the inner layer of the nuclear membrane of all cells.
[]
[ 4452659 ]
688
Lamins have no effect on nuclear membrane structure maintenance.
[]
[ 4452659 ]
689
Less than 10% of patients exposed to radiation have activated markers of mesenchymal stem cells.
[]
[ 22080671 ]
694
Lice attenuated SIV vaccines induce a stronger antigen-specific T cell response in lymph node cells.
[ { "doc_id": 1071991, "sentence_ids": [ 1 ], "label": "SUPPORT" } ]
[ 1071991 ]
696
Lipopolysaccharides have an inflammation independent effect on kidney barrier function.
[]
[ 16355392 ]
698
Lmna knock-in models are appropriate for testing therapeutic approaches against Hutchinson-Gilford progeria syndrome (HGPS).
[]
[ 22544171 ]
703
Localization of PIN1 in the roots of Arabidopsis requires VPS9a
[]
[ 4350400 ]
704
Long - range chromatin interactions regulate transcription.
[]
[ 14658685 ]
705
Long chain polyunsaturated fatty acids supplementation has no significant effects on wheezing or asthma at 3 and 6 years.
[]
[ 22442133 ]
709
Long chain polyunsaturated fatty acids supplementation is associated with lower rates of atopic eczema at 1 year.
[ { "doc_id": 22442133, "sentence_ids": [ 6 ], "label": "SUPPORT" }, { "doc_id": 22442133, "sentence_ids": [ 8 ], "label": "SUPPORT" } ]
[ 22442133 ]
710
Long chain polyunsaturated fatty acids supplementation reduces wheezing and asthma.
[]
[ 22442133 ]
713
Low expression of miR7a does not repress target genes or exert a biological function in ovaries.
[]
[ 18421962 ]
714
Low expression of miR7a does not repress target genes or exert a biological function in testis.
[]
[ 18421962 ]
717
Low nucleosome occupancy correlates with high methylation levels across species.
[ { "doc_id": 17587795, "sentence_ids": [ 4 ], "label": "SUPPORT" } ]
[ 17587795 ]
724
Ly49Q directs the organization of neutrophil polarization by regulating membrane raft functions.
[ { "doc_id": 5531479, "sentence_ids": [ 5 ], "label": "SUPPORT" }, { "doc_id": 5531479, "sentence_ids": [ 6 ], "label": "SUPPORT" } ]
[ 5531479 ]
726
Ly6C hi monocytes have a higher inflammatory capacity than Ly6C lo monocytes.
[ { "doc_id": 36444198, "sentence_ids": [ 9 ], "label": "SUPPORT" }, { "doc_id": 36444198, "sentence_ids": [ 10 ], "label": "SUPPORT" } ]
[ 7521113, 36444198 ]
730
Lysine histone demethylase inhibitor JIB 04 is inactive against KDM5A.
[]
[ 13400643 ]
732
M. stadtmanae does not induce ASC speck formation in BlaER1 monocytes.
[]
[ 34469966 ]
733
M. stadtmanae induces ASC speck formation in BlaER1 monocytes.
[]
[ 34469966 ]
734
MEK inhibitors are effective treatments in RAS-driven mouse models of cancer.
[ { "doc_id": 4961038, "sentence_ids": [ 7 ], "label": "SUPPORT" } ]
[ 4961038 ]
736
MFGE8 regulates fat absorption by binding to av-Beta3 and av-Beta5 integrins.
[ { "doc_id": 5389095, "sentence_ids": [ 4 ], "label": "SUPPORT" } ]
[ 5389095 ]
737
MICAL redox enzymes regulate actin dynamics in many cell types.
[ { "doc_id": 16562534, "sentence_ids": [ 4 ], "label": "SUPPORT" }, { "doc_id": 16562534, "sentence_ids": [ 6 ], "label": "SUPPORT" }, { "doc_id": 6609935, "sentence_ids": [ 3 ], "label": "SUPPORT" } ]
[ 16562534, 6609935 ]
738
MICAL redox enzymes regulate actin dynamics.
[ { "doc_id": 16562534, "sentence_ids": [ 3 ], "label": "SUPPORT" }, { "doc_id": 16562534, "sentence_ids": [ 6 ], "label": "SUPPORT" }, { "doc_id": 6609935, "sentence_ids": [ 3 ], "label": "SUPPORT" }, { "doc_id": 6609935, "sentence_ids": [ 4 ], "label": "SUPPORT" }, { "doc_id": 6609935, "sentence_ids": [ 6 ], "label": "SUPPORT" }, { "doc_id": 33912020, "sentence_ids": [ 2, 3, 5 ], "label": "SUPPORT" } ]
[ 16562534, 6609935, 33912020 ]
739
MT binding domain drives amyloid structure formation.
[]
[ 4446814 ]
740
MUC1-C activates the NF-κB p65 signaling pathway by interacting with IκB kinase ß.
[ { "doc_id": 23078022, "sentence_ids": [ 8 ], "label": "SUPPORT" } ]
[ 23078022 ]
745
MafA phosphorylation decreases its ubiquitination.
[ { "doc_id": 11291348, "sentence_ids": [ 5 ], "label": "CONTRADICT" } ]
[ 11291348 ]
746
MafA phosphorylation enhances its ubiquitination.
[ { "doc_id": 11291348, "sentence_ids": [ 5 ], "label": "SUPPORT" } ]
[ 11291348 ]
747
MafA ubiquitination decreases the recruitment of coavtivator P/CAF by MafA.
[ { "doc_id": 11291348, "sentence_ids": [ 6 ], "label": "CONTRADICT" } ]
[ 11291348 ]
748
MafA ubiquitination increases the recruitment of coavtivator P/CAF by MafA.
[ { "doc_id": 11291348, "sentence_ids": [ 6 ], "label": "SUPPORT" } ]
[ 11291348 ]
749
Major antigen-induced signals from the T cell receptor and secondary signals from costimulatory receptors are required for T cell activation.
[ { "doc_id": 13868795, "sentence_ids": [ 0 ], "label": "SUPPORT" } ]
[ 13868795 ]
751
Major vault protein (MVP) leads to more aggressive tumors by regulating the sorting of tumor suppressive miR-193a into extracellular vesicles (EVs).
[ { "doc_id": 19800147, "sentence_ids": [ 4 ], "label": "SUPPORT" }, { "doc_id": 19800147, "sentence_ids": [ 7 ], "label": "SUPPORT" } ]
[ 19800147 ]
752
Major vault protein regulates sorting of tumor suppressive miR-193a into EVs.
[ { "doc_id": 19800147, "sentence_ids": [ 4 ], "label": "SUPPORT" } ]
[ 19800147 ]
753
Malaria has a high vectorial capacity.
[]
[ 1173667 ]
755
Many cytokines that are produced by cancer cells also contribute to carcinogenesis.
[]
[ 17844478 ]
757
Many transmembrane receptors transmit signals by long-range conformational changes in the association of alpha-helices across the plasma membrane.
[]
[ 17123657 ]
758
Marmosets have a brain region homologous to Broca's area.
[]
[ 14195528 ]
760
Mathematical models predict that using Artemisinin-based combination therapy over nongametocytocidal drugs have only a modest impact in reducing malaria transmission.
[ { "doc_id": 1805641, "sentence_ids": [ 13 ], "label": "SUPPORT" } ]
[ 1805641 ]
761
MeCP2 influences the synaptic maturation of neurons.
[]
[ 10009203 ]
762
Measuring routine outcomes is more beneficial to clinical practice than assessing treatment adherence.
[]
[ 4695046 ]
764
Medications to treat obesity are highly effective.
[ { "doc_id": 7552215, "sentence_ids": [ 8 ], "label": "CONTRADICT" }, { "doc_id": 7552215, "sentence_ids": [ 12 ], "label": "CONTRADICT" } ]
[ 7552215 ]
765
Medications to treat obesity do not have side effects.
[ { "doc_id": 7552215, "sentence_ids": [ 10 ], "label": "CONTRADICT" }, { "doc_id": 7552215, "sentence_ids": [ 11 ], "label": "CONTRADICT" }, { "doc_id": 7552215, "sentence_ids": [ 12 ], "label": "CONTRADICT" } ]
[ 7552215 ]
766
Medications to treat obesity have unwanted side effects.
[ { "doc_id": 7552215, "sentence_ids": [ 10 ], "label": "SUPPORT" }, { "doc_id": 7552215, "sentence_ids": [ 11 ], "label": "SUPPORT" }, { "doc_id": 7552215, "sentence_ids": [ 12 ], "label": "SUPPORT" } ]
[ 7552215 ]
767
Men are more susceptible to death due to pneumonia when compared to women.
[ { "doc_id": 2488880, "sentence_ids": [ 10 ], "label": "CONTRADICT" } ]
[ 2488880 ]
771
Metastatic colorectal cancer treated with a single agent fluoropyrimidines resulted in similar efficacy and better quality of life when compared with oxaliplatin-based chemotherapy in elderly patients.
[ { "doc_id": 15476777, "sentence_ids": [ 16 ], "label": "CONTRADICT" } ]
[ 15476777 ]
772
Mice are incapable of producing neutralizing antibodies in reponse to the Chikungunya virus (CHIKV) produced in mosquitos.
[ { "doc_id": 24922825, "sentence_ids": [ 7 ], "label": "CONTRADICT" } ]
[ 24922825 ]
774
Mice defective for deoxyribonucleic acid (DNA) polymerase I (polI) fail to reveal increased sensitivity to ionizing radiation (IR).
[]
[ 32275758 ]
776
Mice defective for deoxyribonucleic acid (DNA) polymerase m (polm) fail to reveal increased sensitivity to ionizing radiation (IR).
[]
[ 32275758 ]
777
Mice defective for deoxyribonucleic acid (DNA) polymerase m (polm) reveal increased sensitivity to ionizing radiation (IR).
[]
[ 32275758 ]
778
Mice lacking Sirt1 in Sf1-expressing neurons are immune to diet-induced obesity and insulin resistance.
[ { "doc_id": 13001323, "sentence_ids": [ 2, 3 ], "label": "CONTRADICT" }, { "doc_id": 13001323, "sentence_ids": [ 5 ], "label": "CONTRADICT" } ]
[ 13001323 ]
779
Mice lacking Sirt1 in Sf1-expressing neurons have increased susceptibility to diet-induced obesity and insulin resistance.
[ { "doc_id": 13001323, "sentence_ids": [ 2, 3 ], "label": "SUPPORT" }, { "doc_id": 13001323, "sentence_ids": [ 5 ], "label": "SUPPORT" } ]
[ 13001323 ]
780
Mice that lack Interferon-γ or its receptor are highly susceptible to experimental autoimmune myocarditis.
[ { "doc_id": 8246922, "sentence_ids": [ 7 ], "label": "SUPPORT" }, { "doc_id": 8246922, "sentence_ids": [ 11 ], "label": "SUPPORT" }, { "doc_id": 24338780, "sentence_ids": [ 2 ], "label": "SUPPORT" }, { "doc_id": 24338780, "sentence_ids": [ 3 ], "label": "SUPPORT" }, { "doc_id": 24338780, "sentence_ids": [ 6 ], "label": "SUPPORT" } ]
[ 8246922, 24338780 ]
782
Mice without IFN-γ or its receptor are highly susceptible to EAM induced with α-MyHC/CFA.
[ { "doc_id": 8246922, "sentence_ids": [ 7 ], "label": "SUPPORT" }, { "doc_id": 8246922, "sentence_ids": [ 11 ], "label": "SUPPORT" } ]
[ 8246922 ]
787
Microcin J25 encourages nucleoside triphosphate (NTP) binding.
[ { "doc_id": 4740447, "sentence_ids": [ 1 ], "label": "CONTRADICT" } ]
[ 4740447 ]
788
Microcin J25 inhibits nucleoside triphosphate (NTP) binding.
[ { "doc_id": 4740447, "sentence_ids": [ 1 ], "label": "SUPPORT" } ]
[ 4740447 ]
789
Microglia are an innate immune cell type of the central nervous system.
[ { "doc_id": 15493354, "sentence_ids": [ 2 ], "label": "SUPPORT" }, { "doc_id": 15493354, "sentence_ids": [ 3 ], "label": "SUPPORT" } ]
[ 15493354 ]
790
Microglia are an innate immune cell type of the peripheral nervous system.
[ { "doc_id": 15493354, "sentence_ids": [ 2 ], "label": "CONTRADICT" }, { "doc_id": 15493354, "sentence_ids": [ 3 ], "label": "CONTRADICT" } ]
[ 15493354 ]
791
Migraine with aura is associated with ischemic stroke.
[ { "doc_id": 15984735, "sentence_ids": [ 11 ], "label": "SUPPORT" }, { "doc_id": 15984735, "sentence_ids": [ 16 ], "label": "SUPPORT" } ]
[ 15984735 ]
792
Misunderstandings between doctors and patients can lead to non-adherence.
[ { "doc_id": 3610080, "sentence_ids": [ 6, 7 ], "label": "SUPPORT" } ]
[ 3610080 ]
795
Mitochondria play a major role in apoptosis.
[ { "doc_id": 8551160, "sentence_ids": [ 1 ], "label": "SUPPORT" } ]
[ 8551160 ]
797
Mitochondria play a major role in energy production.
[ { "doc_id": 8551160, "sentence_ids": [ 0 ], "label": "SUPPORT" } ]
[ 8551160 ]
798
Mitochondria play a trivial role in calcium homeostasis.
[ { "doc_id": 8551160, "sentence_ids": [ 1 ], "label": "CONTRADICT" } ]
[ 8551160 ]
799
Moderate consumption of candy and chocolate reduces the risk of cardiovascular disease (CVD).
[]
[ 5293024 ]
801
Monoclonal antibody targeting of N-cadherin encourages castration resistance.
[ { "doc_id": 22180793, "sentence_ids": [ 5 ], "label": "CONTRADICT" } ]
[ 22180793 ]
802
Monoclonal antibody targeting of N-cadherin encourages metastasis.
[ { "doc_id": 22180793, "sentence_ids": [ 4 ], "label": "CONTRADICT" }, { "doc_id": 22180793, "sentence_ids": [ 7 ], "label": "CONTRADICT" } ]
[ 22180793 ]
803
Monoclonal antibody targeting of N-cadherin inhibits castration resistance.
[ { "doc_id": 22180793, "sentence_ids": [ 5 ], "label": "SUPPORT" } ]
[ 22180793 ]
804
Monoclonal antibody targeting of N-cadherin inhibits growth.
[ { "doc_id": 22180793, "sentence_ids": [ 3 ], "label": "SUPPORT" } ]
[ 22180793 ]
807
Most termination events in Okazaki fragments are dictated by initiation patterns.
[ { "doc_id": 36606083, "sentence_ids": [ 4 ], "label": "SUPPORT" } ]
[ 36606083 ]
810
Mouse models can be generated using "artificial spermatids."
[ { "doc_id": 13513790, "sentence_ids": [ 5 ], "label": "SUPPORT" } ]
[ 13513790 ]
812
Mutant mice lacking SVCT2 have severely reduced ascorbic acid levels in both brain and adrenals.
[ { "doc_id": 19799455, "sentence_ids": [ 4, 6 ], "label": "SUPPORT" }, { "doc_id": 19799455, "sentence_ids": [ 8 ], "label": "SUPPORT" } ]
[ 19799455 ]
813
Mutations in G-Beta protein GNB1 are present in many cancers, resulting in loss of interaction with G-alpha subunits and concomitant activation of AKT pathway.
[]
[ 33387953 ]
815
Mutations in RIM1 decrease levels of IME1 RNA.
[ { "doc_id": 8148304, "sentence_ids": [ 1 ], "label": "SUPPORT" }, { "doc_id": 8148304, "sentence_ids": [ 13 ], "label": "SUPPORT" } ]
[ 8148304 ]
816
Mutations in RIM1 raise levels of IME1 RNA.
[ { "doc_id": 8148304, "sentence_ids": [ 1 ], "label": "CONTRADICT" }, { "doc_id": 8148304, "sentence_ids": [ 13 ], "label": "CONTRADICT" } ]
[ 8148304 ]
817
Myelin sheaths are lipid-rich cellular structures.
[]
[ 17814815 ]
818
Myelin sheaths play a role in action potential propagation.
[ { "doc_id": 17814815, "sentence_ids": [ 0 ], "label": "SUPPORT" }, { "doc_id": 17814815, "sentence_ids": [ 2 ], "label": "SUPPORT" } ]
[ 17814815 ]
822
N348I mutations cause resistance to nevirapine.
[ { "doc_id": 15319019, "sentence_ids": [ 13 ], "label": "SUPPORT" } ]
[ 15319019 ]
825
N348I mutations reduce resistance to nevirapine.
[ { "doc_id": 15319019, "sentence_ids": [ 13 ], "label": "CONTRADICT" } ]
[ 15319019 ]
826
NAC destabilizes NO to increase the effect of contrast agents on renal functions.
[]
[ 4678846 ]
828
NAC inhibits the generation of angiotensin-converting enzyme.
[]
[ 4678846 ]
835
NR5A2 does not play a role in development of endometrial tissues.
[ { "doc_id": 15928989, "sentence_ids": [ 5, 6 ], "label": "CONTRADICT" }, { "doc_id": 15928989, "sentence_ids": [ 7 ], "label": "CONTRADICT" } ]
[ 15928989 ]
838
NR5A2 is important in reverse cholesterol transport in humans.
[]
[ 15928989 ]
840
Natriuretic peptides increase susceptibility to diabetes.
[ { "doc_id": 15663829, "sentence_ids": [ 4, 7 ], "label": "CONTRADICT" } ]
[ 15663829 ]
841
Natriuretic peptides protect against diabetes.
[ { "doc_id": 15663829, "sentence_ids": [ 4 ], "label": "SUPPORT" }, { "doc_id": 15663829, "sentence_ids": [ 7 ], "label": "SUPPORT" } ]
[ 15663829 ]
844
Neutrophil extracellular trap (NET) antigens may contain the targeted autoantigens PR3 and MPO.
[ { "doc_id": 17741440, "sentence_ids": [ 1 ], "label": "SUPPORT" } ]
[ 17741440 ]
846
Neutrophils produce IL-1β in response to large particles.
[ { "doc_id": 22696649, "sentence_ids": [ 4 ], "label": "SUPPORT" } ]
[ 22696649 ]
848
Nigerian physicians constitue the largest component of sub-Saharan Africa-trained physicians in the United States.
[]
[ 14500725 ]
853
Nonhuman primates are incapable of producing neutralizing antibodies in reponse to the Eilat virus (EILV) produced in mosquitos.
[ { "doc_id": 24922825, "sentence_ids": [ 7, 8 ], "label": "CONTRADICT" } ]
[ 24922825 ]
854
Nonhypertensive people who are 55 years old have a 90% chance of developing hypertension during their lifetime.
[ { "doc_id": 12206390, "sentence_ids": [ 5 ], "label": "SUPPORT" }, { "doc_id": 12206390, "sentence_ids": [ 9 ], "label": "SUPPORT" } ]
[ 12206390 ]
855
Noninvasive positive pressure ventilation is not predictive of acute respiratory failure after solid organ transplantation.
[ { "doc_id": 8190282, "sentence_ids": [ 8 ], "label": "CONTRADICT" }, { "doc_id": 8190282, "sentence_ids": [ 9 ], "label": "CONTRADICT" }, { "doc_id": 8190282, "sentence_ids": [ 10 ], "label": "CONTRADICT" }, { "doc_id": 8190282, "sentence_ids": [ 12 ], "label": "CONTRADICT" } ]
[ 8190282 ]
856
Nonsteroidal antinflammatory drugs are ineffective as cancer treatments.
[ { "doc_id": 43334921, "sentence_ids": [ 6 ], "label": "CONTRADICT" }, { "doc_id": 43334921, "sentence_ids": [ 8 ], "label": "CONTRADICT" }, { "doc_id": 43334921, "sentence_ids": [ 10 ], "label": "CONTRADICT" } ]
[ 43334921 ]
857
Nonsteroidal antinflammatory drugs show potential anticancer indications.
[ { "doc_id": 43334921, "sentence_ids": [ 6 ], "label": "SUPPORT" }, { "doc_id": 43334921, "sentence_ids": [ 8 ], "label": "SUPPORT" }, { "doc_id": 43334921, "sentence_ids": [ 10 ], "label": "SUPPORT" } ]
[ 43334921 ]
858
Normal expression of RUNX1 causes tumorsupressing effects.
[ { "doc_id": 1982286, "sentence_ids": [ 3 ], "label": "SUPPORT" } ]
[ 1982286 ]
860
Normal granulomas form in the absence of TNF in Zebrafish.
[ { "doc_id": 16066726, "sentence_ids": [ 4 ], "label": "SUPPORT" }, { "doc_id": 16066726, "sentence_ids": [ 5 ], "label": "SUPPORT" } ]
[ 16066726 ]
861
Normal granulomas form in the presence of TNF in Zebrafish.
[ { "doc_id": 16066726, "sentence_ids": [ 4 ], "label": "CONTRADICT" }, { "doc_id": 16066726, "sentence_ids": [ 5 ], "label": "CONTRADICT" } ]
[ 16066726 ]
863
Notch signaling occurs between tumor cells and stromal cells.
[ { "doc_id": 20568364, "sentence_ids": [ 1 ], "label": "SUPPORT" }, { "doc_id": 20568364, "sentence_ids": [ 4 ], "label": "SUPPORT" }, { "doc_id": 16361581, "sentence_ids": [ 1 ], "label": "SUPPORT" } ]
[ 20568364, 16361581 ]
866
Nuclear transfer from adult human fibroblasts to human oocytes can give rise to blastocysts containing expandable pluripotent cells.
[]
[ 37822406 ]
867
Oat tolerant coeliac patients may have oat specific inflammatory cells in their small bowel mucosa.
[ { "doc_id": 14340571, "sentence_ids": [ 6 ], "label": "SUPPORT" } ]
[ 14340571 ]