Datasets:

bigbio

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[ { "id": "@@23115445595_text", "type": "sentence", "text": [ "Studies also have alluded to a relationship between the MSMR cyst and certain signs or symptoms of disease ." ], "offsets": [ [ 0, 108 ] ] } ]

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[ { "id": "@@83324922033_text", "type": "sentence", "text": [ "One member of this multigene family , GATA-3 , is most abundantly expressed in T lymphocytes , a cellular target for human immunodeficiency virus type 1 ( HIV-1 ) infection and replication ." ], "offsets": [ [ 0, 190 ] ] } ]

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[ { "id": "@@10595315422_text", "type": "sentence", "text": [ "There were minimal negative effects on hematological parameters , acid-base status , and blood gases ." ], "offsets": [ [ 0, 102 ] ] } ]

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[ { "id": "@@105103797439_text", "type": "sentence", "text": [ "A crucial transcription factor in this process is STAT6 , which binds to a specific DNA element upon cytokine activation ." ], "offsets": [ [ 0, 122 ] ] } ]

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[ { "id": "@@7720709378_text", "type": "sentence", "text": [ "Using Ki-ras-transformed 3T3 cells as a model system , we show that both RA and the 'dissociating' retinoids inhibit anchorage-independent cell proliferation , suggesting that retinoid-induced growth inhibition may be related to AP1 transrepression ." ], "offsets": [ [ 0, 250 ] ] } ]

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[ { "id": "@@34480354154_text", "type": "sentence", "text": [ "Ovarian tumors in pregnancy ." ], "offsets": [ [ 0, 29 ] ] } ]

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[ { "id": "@@87987624540_text", "type": "sentence", "text": [ "Altogether , our results indicate that the transcriptional activity of Cut proteins is modulated by PKC ." ], "offsets": [ [ 0, 105 ] ] } ]

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[ { "id": "@@36870784351_text", "type": "sentence", "text": [ "References for occupational fitness of adolescents with diseases of the respiratory tract and lungs ." ], "offsets": [ [ 0, 101 ] ] } ]

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[ { "id": "@@33089095673_text", "type": "sentence", "text": [ "Lysosomal enzymes that degrade cartilage are released ." ], "offsets": [ [ 0, 55 ] ] } ]

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[ { "id": "@@98068261992_text", "type": "sentence", "text": [ "We have previously mapped the defect in RIIIS / J to distal mouse Chr 11 , distinct from the Vwf locus on Chr 6 ." ], "offsets": [ [ 0, 113 ] ] } ]

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[ { "id": "@@30279053455_text", "type": "sentence", "text": [ "Plasma renin activity rose and the plasma aldosterone level fell after taking lisinopril ." ], "offsets": [ [ 0, 90 ] ] } ]

[ { "id": "@@30279053455_1", "type": "NEWGENE", "text": [ "renin" ], "offsets": [ [ 7, 12 ] ], "normalized": [] } ]

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[ { "id": "@@4885345226_text", "type": "sentence", "text": [ "In addition a significant Treatment X Strain interaction was due to the larger defecation numbers displayed by the taurine-injected MR rats relative to the saline-injected MR rats ." ], "offsets": [ [ 0, 181 ] ] } ]

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[ { "id": "@@107752671048_text", "type": "sentence", "text": [ "Retroviral transduction of T / T ( L ) causes a rapidly fatal myeloproliferative disease in a murine bone marrow transplant ( BMT ) model , whereas T / T ( F ) causes a long-latency , pre-B-cell lymphoblastic lymphoma ." ], "offsets": [ [ 0, 219 ] ] } ]

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[ { "id": "@@94596855443_text", "type": "sentence", "text": [ "Typical configurations of psychosocial stress factors of psychiatrically conspicuous children and adolescents ." ], "offsets": [ [ 0, 111 ] ] } ]

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[ { "id": "@@790367099_text", "type": "sentence", "text": [ "The mutant allele of the alpha 1-tubulin gene was designated tua1-1 ." ], "offsets": [ [ 0, 69 ] ] } ]

[ { "id": "@@790367099_1", "type": "NEWGENE", "text": [ "alpha 1-tubulin" ], "offsets": [ [ 25, 40 ] ], "normalized": [] } ]

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[ { "id": "@@111776861018_text", "type": "sentence", "text": [ "Treatment includes both medical and surgical options , with medical therapy further subclassified into pharmacologic and pneumatic dilation ." ], "offsets": [ [ 0, 141 ] ] } ]

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[ { "id": "@@78166306762_text", "type": "sentence", "text": [ "Similarly approximately 300 bp of sequence downstream of the translation terminator TGA of the beta-tubulin 2 ( BTU2 ) gene could substitute for the 3' region of the H4-I gene ." ], "offsets": [ [ 0, 177 ] ] } ]

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[ { "id": "@@85498597007_text", "type": "sentence", "text": [ "The gene was uniquely mapped with odds > 1 , 000 : 1 on chromosome 3p in Centre d'Etude du Polymorphisme Humain pedigrees ." ], "offsets": [ [ 0, 123 ] ] } ]

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[ { "id": "@@112569446460_text", "type": "sentence", "text": [ "Furthermore , the soluble forms of ATF6 and the G13 gene product are unable to bind to several point mutants of the cis-acting ER stress response element in vitro that hardly respond to ER stress in vivo ." ], "offsets": [ [ 0, 205 ] ] } ]

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[ { "id": "@@38820295711_text", "type": "sentence", "text": [ "A retrospective study of banked sera from 19 cats with the eosinophilic granuloma complex revealed that 68% of affected cats had circulating antibodies to components of normal cat epithelium ." ], "offsets": [ [ 0, 192 ] ] } ]

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[ { "id": "@@80905718067_text", "type": "sentence", "text": [ "Elimination of natural antibodies in discordant xenografts ." ], "offsets": [ [ 0, 60 ] ] } ]

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[ { "id": "@@106012801872_text", "type": "sentence", "text": [ "The first one is a TPA-responsive element that controls the base-line ST3 promoter activity but is not required for its activation ." ], "offsets": [ [ 0, 132 ] ] } ]

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[ { "id": "@@105518797224_text", "type": "sentence", "text": [ "Cyclic AMP-dependent protein kinase binding to A-kinase anchoring proteins in living cells by fluorescence resonance energy transfer of green fluorescent protein fusion proteins ." ], "offsets": [ [ 0, 179 ] ] } ]

[ { "id": "@@105518797224_1", "type": "NEWGENE", "text": [ "A-kinase anchoring proteins" ], "offsets": [ [ 47, 74 ] ], "normalized": [] } ]

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[ { "id": "@@110492411173_text", "type": "sentence", "text": [ "RESULTS : In the pregnant group , serum PP14 concentrations were markedly increased after ET , and a significant difference between the pregnant group and the nonpregnant group was observed 8 days following ET ( p < 0 . 01 ) ." ], "offsets": [ [ 0, 226 ] ] } ]

[ { "id": "@@110492411173_1", "type": "NEWGENE", "text": [ "serum PP14" ], "offsets": [ [ 34, 44 ] ], "normalized": [] } ]

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[ { "id": "@@8552095934_text", "type": "sentence", "text": [ "Paf1p may therefore be required for both positive and negative regulation of subsets of yeast genes ." ], "offsets": [ [ 0, 101 ] ] } ]

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[ { "id": "@@25261658246_text", "type": "sentence", "text": [ "The sign of Leser-Trelat : does it exist ? The sign of Leser-Trelat is usually regarded as a reliable cutaneous marker of internal malignancy ." ], "offsets": [ [ 0, 143 ] ] } ]

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[ { "id": "@@92185205609_text", "type": "sentence", "text": [ "We have initiated studies to identify candidate signal transducers that associate with the cytosolic domain ( cd ) of the IL-1R ." ], "offsets": [ [ 0, 129 ] ] } ]

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[ { "id": "@@110718523740_text", "type": "sentence", "text": [ "To test whether or not SOCS-3 also binds to the IGFIR , we cloned human SOCS-3 by reverse transcription-polymerase chain reaction from human skeletal muscle mRNA ." ], "offsets": [ [ 0, 163 ] ] } ]

[ { "id": "@@110718523740_1", "type": "NEWGENE", "text": [ "SOCS-3" ], "offsets": [ [ 23, 29 ] ], "normalized": [] }, { "id": "@@110718523740_2", "type": "NEWGENE", "text": [ "SOCS-3" ], "offsets": [ [ 23, 29 ] ], "normalized": [] } ]

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[ { "id": "@@88358957815_text", "type": "sentence", "text": [ "The CD4 count at which remission occurs may reflect severe immunodeficiency such that risk for AIDS-related infection is high ." ], "offsets": [ [ 0, 127 ] ] } ]

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[ { "id": "@@109610466815_text", "type": "sentence", "text": [ "Platelet counts and function as well as fibrinogen and von Willebrand factor ( vWF ) levels were determined in each sample ." ], "offsets": [ [ 0, 124 ] ] } ]

[ { "id": "@@109610466815_1", "type": "NEWGENE", "text": [ "von Willebrand factor ( vWF )" ], "offsets": [ [ 55, 84 ] ], "normalized": [] } ]

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[ { "id": "@@109189433273_text", "type": "sentence", "text": [ "Developmental toxicity of the class III antiarrhythmic agent almokalant in mice ." ], "offsets": [ [ 0, 81 ] ] } ]

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[ { "id": "@@77899715705_text", "type": "sentence", "text": [ "The absence of other regions of hybridization suggests that there are no closely related sequences ( e . g . , reverse transcribed pseudogenes ) scattered throughout the genome and that if there are closely related genes , they must be clustered near GSTT2 ." ], "offsets": [ [ 0, 258 ] ] } ]

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[ { "id": "@@113691061209_text", "type": "sentence", "text": [ "Recent advances have shown that volatile sulfur is a result of ecological interactions and transformation processes through planktonic food webs ." ], "offsets": [ [ 0, 146 ] ] } ]

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[ { "id": "@@109319509649_text", "type": "sentence", "text": [ "Cdk2 and MAPK precipitates from untreated tumor lysates phosphorylated recombinant wild-type p27 but not the T187A mutant in vitro ." ], "offsets": [ [ 0, 132 ] ] } ]

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[ { "id": "@@105010342705_text", "type": "sentence", "text": [ "Ribonuclease protection assays revealed that hmg1 and hmg2 are differentially expressed in a developmentally- and spatially-modulated manner during morphogenesis of specialized terpenoid-containing pigment glands in embryos ." ], "offsets": [ [ 0, 225 ] ] } ]

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[ { "id": "@@113745593189_text", "type": "sentence", "text": [ "SERS spectra were obtained by vacuum evaporation and casting of p-NTP onto silver island films , and also from colloidal silver solutions ." ], "offsets": [ [ 0, 139 ] ] } ]

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[ { "id": "@@34407802974_text", "type": "sentence", "text": [ "From these results , it is concluded that EDLF has clear vasoconstrictor properties which are not due to adrenergic or calcium entry mechanisms and that there are differences in the vasoconstrictor effects of EDLFs with respect to different vascular beds ." ], "offsets": [ [ 0, 256 ] ] } ]

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[ { "id": "@@80653665508_text", "type": "sentence", "text": [ "Taken together , our data suggest that Dbf8p plays an essential role in chromosome segregation ." ], "offsets": [ [ 0, 96 ] ] } ]

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[ { "id": "@@29680553682_text", "type": "sentence", "text": [ "The HOI induced a nearly fourfold increase in ANF in the elderly , whereas that for the young was threefold ." ], "offsets": [ [ 0, 109 ] ] } ]

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[ { "id": "@@15872672790_text", "type": "sentence", "text": [ "The sequence data now permit a detailed interpretation of the X-ray crystallographic structure of the enzyme and the cloning and expression of the clostridial gene will facilitate site-directed mutagenesis ." ], "offsets": [ [ 0, 207 ] ] } ]

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[ { "id": "@@39566474608_text", "type": "sentence", "text": [ "Dissolution of the Pt-30%Ir microelectrode tip was observed by scanning electron microscopy at charge densities as low as 200 microC / cm2 X ph ( 1 A / cm2 ) , whereas erosion of activated iridium microelectrodes occurred only at the highest charge and current densities ( 3200 microC / cm2 X ph , 16 A / cm2 ) ." ], "offsets": [ [ 0, 312 ] ] } ]

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[ { "id": "@@71074626910_text", "type": "sentence", "text": [ "The steepness of the standard O2 dissociation curve becomes greater during the training period ( increase in Hill's n from 2 . 68 + / - 0 . 10 to 2 . 96 + / - 0 . 15 ) ." ], "offsets": [ [ 0, 169 ] ] } ]

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[ { "id": "@@14362614294_text", "type": "sentence", "text": [ "Subcutaneous administration of the somatostatin analogue , octreotide , 100 micrograms thrice daily , resulted in a sustained improvement in diarrhoea and disappearance of faecal incontinence without reducing calcitonin levels ." ], "offsets": [ [ 0, 228 ] ] } ]

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[ { "id": "@@75994497500_text", "type": "sentence", "text": [ "The fracture groups were significantly older and had more years since menopause than the control groups ." ], "offsets": [ [ 0, 105 ] ] } ]

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[ { "id": "@@102314547606_text", "type": "sentence", "text": [ "Total serum calcium was 7 . 8 + / - 0 . 8 mg / dl , whereas ionized calcium was 5 . 7 + / - 0 . 7 mg / dl , phosphorus 3 . 2 + / - 1 . 2 mg / dl , and alkaline phosphatase 149 + / - 48 . 6 U / liter ." ], "offsets": [ [ 0, 200 ] ] } ]

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[ { "id": "@@96411677983_text", "type": "sentence", "text": [ "CONCLUSION : TNF alpha , TGF beta , PDGF and IL-1beta increased LDLr gene expression by increasing sterol-independent and mitogenesis-independent gene transcription ." ], "offsets": [ [ 0, 166 ] ] } ]

[ { "id": "@@96411677983_1", "type": "NEWGENE", "text": [ "LDLr" ], "offsets": [ [ 64, 68 ] ], "normalized": [] } ]

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[ { "id": "@@45516504385_text", "type": "sentence", "text": [ "Cell viability and lysosomal enzymes ." ], "offsets": [ [ 0, 38 ] ] } ]

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[ { "id": "@@57693072452_text", "type": "sentence", "text": [ "Automatic view box ." ], "offsets": [ [ 0, 20 ] ] } ]

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[ { "id": "@@94789718657_text", "type": "sentence", "text": [ "Reporter constructs function in a parallel manner , demonstrating the key role of the AhR in constitutive as well as TCDD-induced expression of Cyp1B1 in mouse embryo fibroblasts ." ], "offsets": [ [ 0, 180 ] ] } ]

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[ { "id": "@@10442493287_text", "type": "sentence", "text": [ "At baseline , serum levels of lycopene and FLOP were abnormally high and serum FLOP was correlated significantly with plasma cyclosporine levels ( r = 0 . 646 , p = 0 . 016 ) ." ], "offsets": [ [ 0, 176 ] ] } ]

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[ { "id": "@@73413467193_text", "type": "sentence", "text": [ "2 . numerous narrow shunt vessels departing continuously from the primary arteries to feed a secondary arterial system which parallels the primary one ." ], "offsets": [ [ 0, 152 ] ] } ]

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[ { "id": "@@111132015904_text", "type": "sentence", "text": [ "Pmt2 is a member of a six-protein family in yeast that catalyzes the first step in O mannosylation of target proteins ." ], "offsets": [ [ 0, 119 ] ] } ]

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[ { "id": "@@86611166823_text", "type": "sentence", "text": [ "Promoter activity was high in cell lines that expressed high levels of endogenous D3 mRNA , as indicated by Northern blot analyses , and was significantly reduced when the promoter was truncated to -122 bp ." ], "offsets": [ [ 0, 207 ] ] } ]

[ { "id": "@@86611166823_1", "type": "NEWGENE", "text": [ "D3" ], "offsets": [ [ 82, 84 ] ], "normalized": [] } ]

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[ { "id": "@@14066887611_text", "type": "sentence", "text": [ "Sequencing analysis has shown that each rap1t allele contains a nonsense mutation within a discrete region between amino acids 663 and 684 ." ], "offsets": [ [ 0, 140 ] ] } ]

[ { "id": "@@14066887611_1", "type": "NEWGENE", "text": [ "rap1t" ], "offsets": [ [ 40, 45 ] ], "normalized": [] } ]

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[ { "id": "@@93715669538_text", "type": "sentence", "text": [ "This protein is present in both HeLa nuclear extracts and S100 extracts but absent from SR protein preparations , suggesting that it is not a classical SR protein ." ], "offsets": [ [ 0, 164 ] ] } ]

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[ { "id": "@@112787132389_text", "type": "sentence", "text": [ "Finally a 10-nucleotide region flanking the exon 4 protein-binding site is homologous to instability elements within five other transcripts , suggesting that a common coding region determinant may exist ." ], "offsets": [ [ 0, 204 ] ] } ]

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[ { "id": "@@65273793205_text", "type": "sentence", "text": [ "Alternating proline / alanine sequence of beta B1 subunit originates from a repetitive DNA sequence ." ], "offsets": [ [ 0, 101 ] ] } ]

[ { "id": "@@65273793205_1", "type": "NEWGENE", "text": [ "beta B1" ], "offsets": [ [ 42, 49 ] ], "normalized": [] } ]

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[ { "id": "@@87312226037_text", "type": "sentence", "text": [ "The distribution and organization of projections from the spinal cervical enlargement to subnucleus reticularis dorsalis ( SRD ) and the neighbouring Cuneate nucleus ( Cu ) area was studied in the rat by using microinjections of Phaseolus vulgaris leucoagglutinin ( PHA-L ) into different laminae around the C7 level ." ], "offsets": [ [ 0, 318 ] ] } ]

[ { "id": "@@87312226037_1", "type": "NEWGENE", "text": [ "Phaseolus vulgaris leucoagglutinin ( PHA-L )" ], "offsets": [ [ 229, 273 ] ], "normalized": [] } ]

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[ { "id": "@@75406076792_text", "type": "sentence", "text": [ "Retreatment of these 2 dogs resulted in a similar , but blunted , response to human immunoglobulin ." ], "offsets": [ [ 0, 100 ] ] } ]

[ { "id": "@@75406076792_1", "type": "NEWGENE", "text": [ "immunoglobulin" ], "offsets": [ [ 84, 98 ] ], "normalized": [] } ]

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[ { "id": "@@88638245775_text", "type": "sentence", "text": [ "Cloning and sequence analyses revealed a second cDNA with a 95-nt deletion in the region coding for the putative second intracellular loop and the fourth transmembrane domain of the 5-HT2C-R ." ], "offsets": [ [ 0, 192 ] ] } ]

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[ { "id": "@@27316717975_text", "type": "sentence", "text": [ "The relative toxicity of nickel oxide ( NiO ) , nickel sulfate hexahydrate ( NiSO4 . 6H2O ) , and nickel subsulfide ( Ni3S2 ) was studied in F344 / N rats and B6C3F1 mice after inhalation exposure for 6 hr / day , 5 days / week , for 13 weeks ." ], "offsets": [ [ 0, 244 ] ] } ]

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[ { "id": "@@3887769139_text", "type": "sentence", "text": [ "In the region Walgau with mixed industrial-rural population an iodine deficiency I was found in 81% and an iodine deficiency II in 45% ." ], "offsets": [ [ 0, 136 ] ] } ]

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[ { "id": "@@13711815123_text", "type": "sentence", "text": [ "We propose that plasmids of the pLS1 family ( pE194 , pADB201 , and pLB4 ) share functional and structural characteristics for the regulation of their copy numbers ." ], "offsets": [ [ 0, 165 ] ] } ]

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[ { "id": "@@27621986086_text", "type": "sentence", "text": [ "Reye's syndrome : reports of 7 cases in the period 1982-1987 ." ], "offsets": [ [ 0, 62 ] ] } ]

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[ { "id": "@@91033829048_text", "type": "sentence", "text": [ "The new FIGO definition of cervical cancer stage IA : a critique ." ], "offsets": [ [ 0, 66 ] ] } ]

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[ { "id": "@@32769243167_text", "type": "sentence", "text": [ "In one of these tumors the observed rearrangement was not due to the insertion of an intact MoMuLV provirus ." ], "offsets": [ [ 0, 109 ] ] } ]

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[ { "id": "@@62514691789_text", "type": "sentence", "text": [ "Among six different library isolates containing 6 . 5- to 7-kb IAP units , some restriction sites were highly conserved whereas others varied in both occurrence and position ." ], "offsets": [ [ 0, 175 ] ] } ]

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[ { "id": "@@62235863835_text", "type": "sentence", "text": [ "Immunochemotherapy with schizophyllan ( SPG ) combined with chemotherapeutic agents was evaluated in two syngeneic tumor-C3H / He mouse systems ." ], "offsets": [ [ 0, 145 ] ] } ]

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[ { "id": "@@115332388747_text", "type": "sentence", "text": [ "Mutation of the octamer element also significantly reduced the ability of HDAC1 to confer repression of inducible HLA-DRA promoter activation ." ], "offsets": [ [ 0, 143 ] ] } ]

[ { "id": "@@115332388747_1", "type": "NEWGENE", "text": [ "HLA-DRA" ], "offsets": [ [ 114, 121 ] ], "normalized": [] } ]

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[ { "id": "@@79772399293_text", "type": "sentence", "text": [ "Outflow obstruction of pancreatic juice , i . e . , \"relative stenosis of the minor papilla , \" was considered to be present in the patients with type II papilla , and , therefore , the patients with type II papilla might suffer from acute pancreatitis resulting from poor drainage of pancreatic juice and excessive pressure in the dorsal duct ." ], "offsets": [ [ 0, 345 ] ] } ]

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[ { "id": "@@35101851393_text", "type": "sentence", "text": [ "Natl ." ], "offsets": [ [ 0, 6 ] ] } ]

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[ { "id": "@@752950429_text", "type": "sentence", "text": [ "Pharmacological and pharmacokinetic characteristics of the non-ionic monomeric X-ray contrast agent iopromide ( Ultravist , CAS 73334-07-3 ) were evaluated in preclinical studies ." ], "offsets": [ [ 0, 180 ] ] } ]

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[ { "id": "@@86082222888_text", "type": "sentence", "text": [ "The membrane-distal cytoplasmic region of human granulocyte colony-stimulating factor receptor is required for STAT3 but not STAT1 homodimer formation ." ], "offsets": [ [ 0, 152 ] ] } ]

[ { "id": "@@86082222888_1", "type": "NEWGENE", "text": [ "STAT1" ], "offsets": [ [ 125, 130 ] ], "normalized": [] }, { "id": "@@86082222888_2", "type": "NEWGENE", "text": [ "granulocyte colony-stimulating factor receptor" ], "offsets": [ [ 48, 94 ] ], "normalized": [] } ]

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[ { "id": "@@100909439186_text", "type": "sentence", "text": [ "The mean value of the CD79b to the CD79b internally deleted ratio was 0 . 64 + / - 0 . 20 SD in normal donors and 0 . 44 + / - 0 . 27 SD in B-CLL ( P = . 01 ) ." ], "offsets": [ [ 0, 160 ] ] } ]

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[ { "id": "@@28377632631_text", "type": "sentence", "text": [ "Amino acid sequence of one human liver clone ( HL-14 ) was identical to the rabbit skeletal muscle phosphatase 2A cDNA ( with 97% nucleotide identity ) ." ], "offsets": [ [ 0, 153 ] ] } ]

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[ { "id": "@@105535518761_text", "type": "sentence", "text": [ "Factor XI deficiency is a rare hereditary bleeding disorder affecting the intrinsic pathway ." ], "offsets": [ [ 0, 93 ] ] } ]

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[ { "id": "@@82256578202_text", "type": "sentence", "text": [ "The effect of ibopamine and furosemide in 130 patients with NYHA Class I and II heart failure were studied in a parallel , double-blind , randomized placebo-controlled multi-centre trial ." ], "offsets": [ [ 0, 188 ] ] } ]

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[ { "id": "@@85954143461_text", "type": "sentence", "text": [ "The assembly of sequence ready , high-resolution physical maps and construction of minimally overlapping contigs for the human as well as model genomes requires accurate determination of the extent of overlap between adjacent clones as well as their relative orientation ." ], "offsets": [ [ 0, 272 ] ] } ]

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[ { "id": "@@3280021981_text", "type": "sentence", "text": [ "The SSB-poly ( dT ) affinity is too high to measure in buffers containing even 5 M NaCl ; however , in 1 . 8-2 . 5 M NaBr , we measure alpha log Kobsd / alpha log [ NaBr ] = -5 . 7 + / - 0 . 7 , with a lower value of omega T / O = 130 + / - 70 ." ], "offsets": [ [ 0, 245 ] ] } ]

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[ { "id": "@@118461677119_text", "type": "sentence", "text": [ "Selenium is an essential element for humans , animals and some species of microorganisms ." ], "offsets": [ [ 0, 90 ] ] } ]

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[ { "id": "@@108118044935_text", "type": "sentence", "text": [ "Consistent with this , we show that peptides representing docking sites within the target substrates Elk-1 and p90 ( rsk ) inhibit ERK-dependent activation of MKP-3 ." ], "offsets": [ [ 0, 166 ] ] } ]

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[ { "id": "@@68728002230_text", "type": "sentence", "text": [ "Acute type A hepatitis in three patients with chronic HBV infection ." ], "offsets": [ [ 0, 69 ] ] } ]

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[ { "id": "@@24773731672_text", "type": "sentence", "text": [ "A potential TATA box is located 29 base pairs upstream of the first transcription initiation site ." ], "offsets": [ [ 0, 99 ] ] } ]

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[ { "id": "@@3392894087_text", "type": "sentence", "text": [ "Use of radioactive isotopes in the chemistry of proteins ." ], "offsets": [ [ 0, 58 ] ] } ]

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[ { "id": "@@88876597703_text", "type": "sentence", "text": [ "Mutations at two neighboring sites , serine 242 and threonine 255 , exacerbated the effect ." ], "offsets": [ [ 0, 92 ] ] } ]

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[ { "id": "@@842758382_text", "type": "sentence", "text": [ "Preface ." ], "offsets": [ [ 0, 9 ] ] } ]

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[ { "id": "@@27323419449_text", "type": "sentence", "text": [ "Light microscopical and routine immunohistochemical studies of a cervical neoplasm in a 32 year old woman initially suggested a histiocytic lymphoma , but histochemical staining for chloroacetate esterase established the correct diagnosis ." ], "offsets": [ [ 0, 240 ] ] } ]

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[ { "id": "@@29273913587_text", "type": "sentence", "text": [ "All of the newly acquired proviruses identified in mosaic founder SWR / J-RF / J mice that could be transmitted through the germ line were also present in somatic tissues , demonstrating that viral integration occurred before the germ line was set aside from the somatic lineages ." ], "offsets": [ [ 0, 281 ] ] } ]

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[ { "id": "@@99037229910_text", "type": "sentence", "text": [ "Autoionization rates and energy levels of triplet nf , v = 1 Rydberg states of H2 ." ], "offsets": [ [ 0, 83 ] ] } ]

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[ { "id": "@@114419521316_text", "type": "sentence", "text": [ "At 20 days ( D ) and at 3 months post-TBI , irradiated rats had a significantly lower percentage of avoidance than controls but no statistical difference was found at 5 months post-TBI . b / Two-way avoidance test : this test was performed only after TBI ." ], "offsets": [ [ 0, 256 ] ] } ]

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[ { "id": "@@40403394715_text", "type": "sentence", "text": [ "Monitoring changes in the heart rate of the premature fetus during tocolysis with the beta-adrenomimetics partusisten and Pre-par ." ], "offsets": [ [ 0, 131 ] ] } ]

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[ { "id": "@@66436126378_text", "type": "sentence", "text": [ "Thin-layer chromatographic methods were up-dated for pharmacokinetic studies of imipramine in plasma and urine ." ], "offsets": [ [ 0, 112 ] ] } ]

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[ { "id": "@@10502216298_text", "type": "sentence", "text": [ "This study was designed to compare the efficacy of efegatran plus streptokinase versus heparin plus accelerated tissue plasminogen activator ( TPA ) in coronary reperfusion in acute MI ." ], "offsets": [ [ 0, 186 ] ] } ]

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[ { "id": "@@95568619512_text", "type": "sentence", "text": [ "Based on the current literature , the mechanisms involved in the toxicity of OA indicate three major effects : ( 1 ) inhibition of mitochondrial respiration correlated with a depletion of ATP ; ( 2 ) inhibition of tRNA-synthetase accompanied by a reduced protein synthesis ; and ( 3 ) enhanced lipid peroxidation ." ], "offsets": [ [ 0, 314 ] ] } ]

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[ { "id": "@@114355783451_text", "type": "sentence", "text": [ "And , most importantly , reconstitution of a consensus CRE , within the 21-bp enhancers increases binding of CREB / ATF proteins but abrogates basal repression of LTR-directed transcription in vitro ." ], "offsets": [ [ 0, 200 ] ] } ]

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[ { "id": "@@71754746997_text", "type": "sentence", "text": [ "The cause of death is often quite apparent from the pathological and toxicological findings ; however , the manner of death often gives the examining official some difficulty ." ], "offsets": [ [ 0, 176 ] ] } ]

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[ { "id": "@@64608896265_text", "type": "sentence", "text": [ "In doses of 0 . 03-0 . 3 mg / kg i . v . , SG-75 did not significantly affect pulse pressure , heart rate , aortic blood flow , left ventricular pressure ( LVP ) and LVdP / dt max ." ], "offsets": [ [ 0, 181 ] ] } ]

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[ { "id": "@@106471771411_text", "type": "sentence", "text": [ "The RNA aptamer contains three stems separated by a pair of two-base bulges , and adopts an unanticipated fold in which both junctional sites are anchored through base triple formation ." ], "offsets": [ [ 0, 186 ] ] } ]

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[ { "id": "@@29823326509_text", "type": "sentence", "text": [ "Phase II study of VP-16 ( capsule ) in solid tumors ." ], "offsets": [ [ 0, 53 ] ] } ]

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[ { "id": "@@80839981866_text", "type": "sentence", "text": [ "These results suggest that leader-mRNA fusion in coronavirus transcription does not require direct RNA-RNA interaction between complementary sequences ." ], "offsets": [ [ 0, 152 ] ] } ]

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