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@@97016167248
@@97016167248
[ { "id": "@@97016167248_text", "type": "sentence", "text": [ "Reverse transcriptase-polymerase chain reaction ( RT-PCR ) was performed using eyestalk complementary DNA of the sand shrimp Metapenaeus ensis ." ], "offsets": [ [ 0, 144 ] ] } ]
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@@11919551832
@@11919551832
[ { "id": "@@11919551832_text", "type": "sentence", "text": [ "This reveals a new test for short saphenous incompetence and shows that 14 per cent of varices stem from a saphenopopliteal reflux ." ], "offsets": [ [ 0, 132 ] ] } ]
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@@20613335965
@@20613335965
[ { "id": "@@20613335965_text", "type": "sentence", "text": [ "These observations , together with the occurrence of putative 4'-phosphopantetheine-attachment sites and a putative thioesterase site , are discussed with reference to the reaction sequence leading to production of the ACV tripeptide ." ], "offsets": [ [ 0, 235 ] ] } ]
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@@98081556319
@@98081556319
[ { "id": "@@98081556319_text", "type": "sentence", "text": [ "Examination of DNA : protein binding complexes by gel-shift analysis indicated that nuclear factors from both proliferative and growth-arrested cells bound to the DNA fragment spanning -949- -722 bp ." ], "offsets": [ [ 0, 200 ] ] } ]
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@@95536864480
@@95536864480
[ { "id": "@@95536864480_text", "type": "sentence", "text": [ "The pharmacokinetic patterns of estradiol ( CAS 50-28-2 ) and of estrone ( CAS 53-16-7 ) were investigated in 18 women in natural or surgical menopause during the application of a new estradiol transdermal patch with active matrix and without absorption enhancers designed for epicutaneous applications of 7 days ( hereinafter called \"patch 7D\" ) ." ], "offsets": [ [ 0, 348 ] ] } ]
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@@2018812629
@@2018812629
[ { "id": "@@2018812629_text", "type": "sentence", "text": [ "A striking finding in all of the studies was a positive correlation between PI ACTH and MSH contents ." ], "offsets": [ [ 0, 102 ] ] } ]
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@@91082797067
@@91082797067
[ { "id": "@@91082797067_text", "type": "sentence", "text": [ "The capacity to repair 8-OxoG has been measured in cell-free extracts of wild-type and ogg1 strains using a 34mer DNA fragment containing a single 8-OxoG residue paired with a cytosine ( 8-OxoG / C ) as a substrate ." ], "offsets": [ [ 0, 216 ] ] } ]
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@@26389649388
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[ { "id": "@@26389649388_text", "type": "sentence", "text": [ "The maximum stress due to the hygroscopic examination of the composite was 0 . 74 kg / mm2 at equilibrium of the water absorbed of the composite ." ], "offsets": [ [ 0, 146 ] ] } ]
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@@9650299343
@@9650299343
[ { "id": "@@9650299343_text", "type": "sentence", "text": [ "VirD2 is one of the key Agrobacterium tumefaciens proteins involved in T-DNA processing and transfer ." ], "offsets": [ [ 0, 102 ] ] } ]
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@@90231973968
@@90231973968
[ { "id": "@@90231973968_text", "type": "sentence", "text": [ "The dnaK operon of Bacillus subtilis is heptacistronic ." ], "offsets": [ [ 0, 56 ] ] } ]
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@@11410110643
@@11410110643
[ { "id": "@@11410110643_text", "type": "sentence", "text": [ "NIRS was used for the quantitative measurement of muscle O ( 2 ) consumption ( mV . O ( 2 ) ) and forearm blood flow ( FBF ) in 78 healthy subjects ." ], "offsets": [ [ 0, 149 ] ] } ]
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@@95141569038
@@95141569038
[ { "id": "@@95141569038_text", "type": "sentence", "text": [ "Alterations in DNase I reactivity of the GC-response element region suggest that GC receptor-GC complexes may associate , in a transient manner , with the promoter in the actively transcribing control state ." ], "offsets": [ [ 0, 208 ] ] } ]
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@@77999257388
@@77999257388
[ { "id": "@@77999257388_text", "type": "sentence", "text": [ "Reconstitution of complexes containing p62 and the src family kinase p59fyn in HeLa cells demonstrated that complex formation resulted in tyrosine phosphorylation of p62 and was mediated by both the SH3 and SH2 domains of p59fyn ." ], "offsets": [ [ 0, 230 ] ] } ]
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@@113211875882
@@113211875882
[ { "id": "@@113211875882_text", "type": "sentence", "text": [ "Sixteen out of 52 seropositive MS patients ( 30 . 8% ) showed intrathecal synthesis of C . pneumoniae-specific IgG but only one of 43 seropositive controls ( 2 . 3% ) ." ], "offsets": [ [ 0, 168 ] ] } ]
[ { "id": "@@113211875882_1", "type": "NEWGENE", "text": [ "IgG" ], "offsets": [ [ 111, 114 ] ], "normalized": [] } ]
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@@18406086909
@@18406086909
[ { "id": "@@18406086909_text", "type": "sentence", "text": [ "The N-terminus of another open reading frame was found 3' from nifA and tentatively identified as nifB by amino acid sequence comparison ." ], "offsets": [ [ 0, 138 ] ] } ]
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@@105451922770
@@105451922770
[ { "id": "@@105451922770_text", "type": "sentence", "text": [ "Phosphatidylinositol 3-kinase requirement in activation of the ras / C-raf-1 / MEK / ERK and p70 ( s6k ) signaling cascade by the insulinomimetic agent vanadyl sulfate ." ], "offsets": [ [ 0, 169 ] ] } ]
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@@10514808342
@@10514808342
[ { "id": "@@10514808342_text", "type": "sentence", "text": [ "Cortical dysplasias , genetics , and epileptogenesis ." ], "offsets": [ [ 0, 54 ] ] } ]
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@@104530063107
@@104530063107
[ { "id": "@@104530063107_text", "type": "sentence", "text": [ "In addition to homologues of the human genes PSMB5 through PSMB9 , two new genes , PSMB11 and PSMB12 , have been found for which there are no known corresponding genes in humans ." ], "offsets": [ [ 0, 179 ] ] } ]
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@@83827698119
@@83827698119
[ { "id": "@@83827698119_text", "type": "sentence", "text": [ "We conclude that the conservation of nucleotides 154 to 156 is likely to be a consequence of their role as a sequence-specific recognition element for the SRP54 protein ." ], "offsets": [ [ 0, 170 ] ] } ]
[ { "id": "@@83827698119_1", "type": "NEWGENE", "text": [ "SRP54" ], "offsets": [ [ 155, 160 ] ], "normalized": [] } ]
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@@31397504299
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[ { "id": "@@31397504299_text", "type": "sentence", "text": [ "The genetic basis for the expression of a latent VH allotype in the rabbit was investigated ." ], "offsets": [ [ 0, 93 ] ] } ]
[ { "id": "@@31397504299_1", "type": "NEWGENE", "text": [ "VH" ], "offsets": [ [ 49, 51 ] ], "normalized": [] } ]
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@@55934695608
@@55934695608
[ { "id": "@@55934695608_text", "type": "sentence", "text": [ "Open head-brain injuries ." ], "offsets": [ [ 0, 26 ] ] } ]
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@@89439288896
@@89439288896
[ { "id": "@@89439288896_text", "type": "sentence", "text": [ "Administration of a second dose of vaccine during the outbreak was not protective ." ], "offsets": [ [ 0, 83 ] ] } ]
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@@82493198235
@@82493198235
[ { "id": "@@82493198235_text", "type": "sentence", "text": [ "Clipping resulted in a serious mislocalization of the position of the peak of the epicortical potential field ." ], "offsets": [ [ 0, 111 ] ] } ]
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@@113779758440
@@113779758440
[ { "id": "@@113779758440_text", "type": "sentence", "text": [ "Unexpectedly , Arg1-expressing COS1 cells showed no significant proteinase activity to various synthesized substrates under neutral or acidic conditions in this study ." ], "offsets": [ [ 0, 168 ] ] } ]
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@@5774405716
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[ { "id": "@@5774405716_text", "type": "sentence", "text": [ "In the duodenum a small part of the administered dose was transformed to 3H-alpha-acetyldigoxin ." ], "offsets": [ [ 0, 97 ] ] } ]
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@@29075338830
@@29075338830
[ { "id": "@@29075338830_text", "type": "sentence", "text": [ "Effects of a perfluorochemical blood substitute on diazepam binding by human albumin ." ], "offsets": [ [ 0, 86 ] ] } ]
[ { "id": "@@29075338830_1", "type": "NEWGENE", "text": [ "albumin" ], "offsets": [ [ 77, 84 ] ], "normalized": [] } ]
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@@92941616192
@@92941616192
[ { "id": "@@92941616192_text", "type": "sentence", "text": [ "These findings suggest one potential mechanism for direct recruitment of distal regulatory regions of the globin loci to the individual promoters ." ], "offsets": [ [ 0, 147 ] ] } ]
[ { "id": "@@92941616192_1", "type": "NEWGENE", "text": [ "globin" ], "offsets": [ [ 106, 112 ] ], "normalized": [] } ]
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@@97617238358
@@97617238358
[ { "id": "@@97617238358_text", "type": "sentence", "text": [ "GETS-1 is expressed in many tissues , but is enriched in retina and brain ." ], "offsets": [ [ 0, 75 ] ] } ]
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@@21230294981
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[ { "id": "@@21230294981_text", "type": "sentence", "text": [ "A second isotype of Raja immunoglobulin heavy chain genes has been detected by screening a spleen cDNA library with homologous Raja VH- and CH1-specific probes complementing the respective regions of the mu-like isotype ." ], "offsets": [ [ 0, 221 ] ] } ]
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@@77573157728
@@77573157728
[ { "id": "@@77573157728_text", "type": "sentence", "text": [ "Thereafter , the aggregation rose to the initial 100% value 4 h after drug application and remained at this level during the observation period . ( ABSTRACT TRUNCATED AT 250 WORDS )" ], "offsets": [ [ 0, 181 ] ] } ]
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@@78597395940
@@78597395940
[ { "id": "@@78597395940_text", "type": "sentence", "text": [ "Lack of cyclin D-Cdk complexes in Rb-negative cells correlates with high levels of p16INK4 / MTS1 tumour suppressor gene product ." ], "offsets": [ [ 0, 130 ] ] } ]
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@@19528272574
@@19528272574
[ { "id": "@@19528272574_text", "type": "sentence", "text": [ "At the time of the seizure , the patient was asked to read a test phrase aloud until it was read correctly and clearly ." ], "offsets": [ [ 0, 120 ] ] } ]
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@@73691837208
@@73691837208
[ { "id": "@@73691837208_text", "type": "sentence", "text": [ "Two new artifacts in automated coagulation testing ." ], "offsets": [ [ 0, 52 ] ] } ]
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@@97317041544
@@97317041544
[ { "id": "@@97317041544_text", "type": "sentence", "text": [ "This study examines the cooperative effects of a human estrogen receptor-alpha ( ERalpha ) isoform on estrogen ( E2 ) -mediated gene activation in U2-OS osteosarcoma cells ." ], "offsets": [ [ 0, 173 ] ] } ]
[ { "id": "@@97317041544_1", "type": "NEWGENE", "text": [ "estrogen ( E2 )" ], "offsets": [ [ 102, 117 ] ], "normalized": [] }, { "id": "@@97317041544_2", "type": "NEWGENE", "text": [ "human estrogen receptor-alpha ( ERalpha )" ], "offsets": [ [ 49, 90 ] ], "normalized": [] }, { "id": "@@97317041544_3", "type": "NEWGENE", "text": [ "human estrogen receptor-alpha ( ERalpha ) isoform" ], "offsets": [ [ 49, 98 ] ], "normalized": [] }, { "id": "@@97317041544_4", "type": "NEWGENE", "text": [ "estrogen receptor-alpha ( ERalpha )" ], "offsets": [ [ 55, 90 ] ], "normalized": [] }, { "id": "@@97317041544_5", "type": "NEWGENE", "text": [ "( ERalpha ) isoform" ], "offsets": [ [ 79, 98 ] ], "normalized": [] }, { "id": "@@97317041544_6", "type": "NEWGENE", "text": [ "estrogen receptor-alpha ( ERalpha ) isoform" ], "offsets": [ [ 55, 98 ] ], "normalized": [] }, { "id": "@@97317041544_7", "type": "NEWGENE", "text": [ "human estrogen receptor-alpha" ], "offsets": [ [ 49, 78 ] ], "normalized": [] } ]
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@@100229051336
@@100229051336
[ { "id": "@@100229051336_text", "type": "sentence", "text": [ "Three mog-1 alleles possess premature stop codons and are likely to be null alleles , and one is a missense mutation and is likely to retain residual activity . mog-1 mRNA is expressed in both germ line and somatic tissues and appears to be ubiquitous ." ], "offsets": [ [ 0, 253 ] ] } ]
[ { "id": "@@100229051336_1", "type": "NEWGENE", "text": [ "mog-1" ], "offsets": [ [ 6, 11 ] ], "normalized": [] }, { "id": "@@100229051336_2", "type": "NEWGENE", "text": [ "mog-1" ], "offsets": [ [ 6, 11 ] ], "normalized": [] } ]
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@@92996969258
@@92996969258
[ { "id": "@@92996969258_text", "type": "sentence", "text": [ "The distribution of cryptosporidia in the intestine and number of cryptosporidia per ileal villus on different DPI were also estimated for detailed characterization of the infection in kids as a model for experimental cryptosporidiosis ." ], "offsets": [ [ 0, 237 ] ] } ]
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@@105728669521
@@105728669521
[ { "id": "@@105728669521_text", "type": "sentence", "text": [ "Marked hemolysis significantly increased plasma values of potassium , phosphorus , total protein , and aspartate aminotransferase ." ], "offsets": [ [ 0, 131 ] ] } ]
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@@93267274243
@@93267274243
[ { "id": "@@93267274243_text", "type": "sentence", "text": [ "The regurgitation of large vitreous injections ." ], "offsets": [ [ 0, 48 ] ] } ]
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@@1101272843
@@1101272843
[ { "id": "@@1101272843_text", "type": "sentence", "text": [ "Assessment of the carcinogenicity of non-nutritive sweetners II : Cyclamates and cyclohexylamine ." ], "offsets": [ [ 0, 98 ] ] } ]
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@@112005684754
@@112005684754
[ { "id": "@@112005684754_text", "type": "sentence", "text": [ "Blood from dams was collected prior to inoculation and at time of necropsy for measurement of IgM and IgG antibodies to M . pulmonis ." ], "offsets": [ [ 0, 134 ] ] } ]
[ { "id": "@@112005684754_1", "type": "NEWGENE", "text": [ "IgG" ], "offsets": [ [ 102, 105 ] ], "normalized": [] } ]
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@@87871102376
@@87871102376
[ { "id": "@@87871102376_text", "type": "sentence", "text": [ "We conclude that CPET is a useful investigation in the management of patients with cardiopulmonary disease and complements the various other investigations offered by a pulmonary function laboratory ." ], "offsets": [ [ 0, 200 ] ] } ]
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@@22736902921
@@22736902921
[ { "id": "@@22736902921_text", "type": "sentence", "text": [ "Effects of cisapride on upper-gastrointestinal motility and digestive hormones ." ], "offsets": [ [ 0, 80 ] ] } ]
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@@24235336259
@@24235336259
[ { "id": "@@24235336259_text", "type": "sentence", "text": [ "The cDNAs cross-hybridize with genomic sequences in rat , human , and chicken DNA , but not with DNA from frog , Drosophila , or sea urchin ." ], "offsets": [ [ 0, 141 ] ] } ]
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@@57326415679
@@57326415679
[ { "id": "@@57326415679_text", "type": "sentence", "text": [ "Trials of sevine activity against mosquito larvae ." ], "offsets": [ [ 0, 51 ] ] } ]
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@@104873079285
@@104873079285
[ { "id": "@@104873079285_text", "type": "sentence", "text": [ "Immediately before surgery patients received either intravenous hydrocortisone 100 mg or placebo in random , double-blind order ." ], "offsets": [ [ 0, 129 ] ] } ]
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@@105061439955
@@105061439955
[ { "id": "@@105061439955_text", "type": "sentence", "text": [ "In HeLa cells , the JNKK2-JNK1 fusion protein showed significant JNK activity , which was comparable with that of JNK1 activated by many stimuli and activators , including EGF , TNF-alpha , anisomycin , UV irradiation , MEKK1 , and small GTP binding proteins Rac1 and Cdc42Hs ." ], "offsets": [ [ 0, 277 ] ] } ]
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@@1732752685
@@1732752685
[ { "id": "@@1732752685_text", "type": "sentence", "text": [ "In some early B cells and Abelson murine leukemia virus-transformed pre-B-cell lines , LT mRNA is constitutively expressed ." ], "offsets": [ [ 0, 124 ] ] } ]
[ { "id": "@@1732752685_1", "type": "NEWGENE", "text": [ "LT" ], "offsets": [ [ 87, 89 ] ], "normalized": [] } ]
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@@96015169888
@@96015169888
[ { "id": "@@96015169888_text", "type": "sentence", "text": [ "Substitution of bulky hydrophobic residues with charged residues within PEP1 affects the fusion activity of the S protein without affecting processing and surface expression ." ], "offsets": [ [ 0, 175 ] ] } ]
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@@79353797380
@@79353797380
[ { "id": "@@79353797380_text", "type": "sentence", "text": [ "The dying tTG-transfected cells exhibit both cytoplasmic and nuclear changes characteristic of cells undergoing apoptosis ." ], "offsets": [ [ 0, 123 ] ] } ]
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@@79666028959
@@79666028959
[ { "id": "@@79666028959_text", "type": "sentence", "text": [ "Roizman , J ." ], "offsets": [ [ 0, 13 ] ] } ]
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@@10684646195
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[ { "id": "@@10684646195_text", "type": "sentence", "text": [ "In this study , a common mechanism has been identified to coordinate the growth- and FC-dependent expression of caveolin ." ], "offsets": [ [ 0, 122 ] ] } ]
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@@88103236894
@@88103236894
[ { "id": "@@88103236894_text", "type": "sentence", "text": [ "There are four polyglutamine motifs interspersed with histidine-rich regions ." ], "offsets": [ [ 0, 78 ] ] } ]
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@@75852464490
@@75852464490
[ { "id": "@@75852464490_text", "type": "sentence", "text": [ "SL1 trans-splicing specified by AU-rich synthetic RNA inserted at the 5' end of Caenorhabditis elegans pre-mRNA ." ], "offsets": [ [ 0, 113 ] ] } ]
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@@89971215
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[ { "id": "@@89971215_text", "type": "sentence", "text": [ "When CSF [ HCO3- ] is shown as a function of CSF PCO2 the data of K-depleted rats are no longer displaced when compared to controls but still have a significantly greater slope ( 1 . 21 + / - 0 . 23 vs ." ], "offsets": [ [ 0, 203 ] ] } ]
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@@16696112263
@@16696112263
[ { "id": "@@16696112263_text", "type": "sentence", "text": [ "The patient with a prolonged fever caused by dissecting aneurysm of the aorta in whom pleuropneumonia masked the real diseases has been presented ." ], "offsets": [ [ 0, 147 ] ] } ]
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@@96501869621
@@96501869621
[ { "id": "@@96501869621_text", "type": "sentence", "text": [ "The low number of false positives indicates that our scheme would not confuse the radiologist by suggesting normal regions as suspicious ." ], "offsets": [ [ 0, 138 ] ] } ]
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@@82939933870
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