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Nordic has enjoyed regularly elite KLAS rankings, including prime performer in Epic IT Advisory solutions in the most current Epic Consulting 2016 report © KLAS Enterprises, LLC. To remain ahead of the wave of commoditization, firms will need human, brand, technological, and financial sources to deploy against new and increasingly complex problems and to create new intellectual property. M&A activity, as hard as that may be, will improve as some firms make a decision that they never have the sources or stamina to make necessary changes, and other people recognize the require to obtain fill-in capability.
International Federation of Consulting Engineers (FIDIC) is a Federation whose members are national associations of Consulting Engineers. Your job, then, becomes harder, due to the fact you are marketing your solutions to people who may possibly not even be conscious that they need those services.
As in law, for consumers facing bet the business” strategic problems, paying leading dollar for name-brand answer shops will make sense, if for no other reason than that board members will not question the analytics developed by prestigious firms. The International Council of Management Consulting Institutes (ICMCI) was founded in 1987 and has around 50 member institutes covering the globe.
If our extended study of disruption has led us to any universal conclusion, it is that every sector will at some point face it. The leaders of the legal services business would after have held that the franchise of the top firms was virtually unassailable, enshrined in practice and tradition—and, in several nations, in law.
The Big Four accounting and auditing firms are the world’s most credible accounting companies, offering audit, tax, bookkeeping and all accounting solutions for private and public corporations globally. For more than 60 years, our consultants have developed and implemented profound business transformations in partnership with the world’s top businesses.
Management consulting is not a regulated profession so many individuals that style themselves as management consultants are not CMC’s. The Department of Statistics provides a Statistical Consulting Service staffed by sophisticated graduate students in Statistics. |
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Every year, I like to host a little ‘thank you’ event for my readers (yes, that means YOU) to show you all just how much I appreciate your support. The 12 Days of Jolly Giveaways begins just after Thanksgiving and runs through Christmas of each year. Simply sign up for Cake ‘n Knife emails to receive the latest updates!
Click here to sign up for Cake ‘n Knife’s email list.
To check out past and current 12 Days of Jolly Giveaway posts, click on the year below for the recipes and giveaways! |
This role is responsible for day to day processing of financial transactions to ensure that municipal finances are maintained in an effective, up to date and accurate manner along with general administrative support to the finance and accounting team member.
Complimentary VA fitness club membership for you & a buddy!
If you're interested in this position simply apply online now! |
Flirt with classical romance in our Hedy range. Charm in our classic high-waist suspender brief with a tempting surprise! Our Hedy big brief features an elegant lay of symmetrical black eyelash lace over peach stretch satin. Turn around for a surprise of the cut-out peek-a-boo behind, finished with a darted downwards seam to enhance the sweetheart shape of your bottom! Our big brief features 4 detachable suspender straps best worn with the matching Hedy longline bra for a timeless vintage look. The peek-a-boo brief is skirted with power mesh for a flirty, yet comfortable wear. |
(CNN) – McDonalds has a new breakfast item, donuts sticks.
The fried fried dough come in packs of 6 or 12 served hot with cinnamon and sugar.
McDonald's hopes to increase sales for breakfast, which have slipped in recent years amid growing competition from fast food restaurants.
The company announced in October that it would expand its breakfast menu, but did not specify at the time. It is not clear if more will be added to the breakfast menu.
Although McDonald's now offers full-day breakfasts, donut sticks will only be available during normal breakfast hours. |
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Dimensions : H 40 x Ø 40 cm.
Cult object of design, the Cobra lamp was created by Elio Martinelli in 1965. This lamp of office or table with broadcasts light is orientable thanks to his articulated arm. The broadcaster and the structure are in white resin. Mythical, Cobra are exposed in the biggest museums of the entire world. |
Uploaded by LISA DAMAYANTI in Alexandria at Wednesday, February 19, 2014. The Marvelous Outdoor Ideas images on this page are the Marvelous image that we picked for you with a dimension of 800 x 600 pixels. Unique Cedar Shake Building above are the same as what I saw when I visited my mother�s villa in San Diego, US. Don�t be hesitate; you can also find the whole information in the Great Cedar Shake Building Decoration which contains image that I took during a trip to various Lands such as Germany, Romania, and Guyana.
Feel free to use the cedar shake panels image that I provided even though you are in tropical or desert Lands like Thailand, Macau, and Ivory Coast. Download by right clicking your mouse right on the Marvelous image, then give this high definition image to your home architect to be used soon. |
Slots games can be loads of fun and there is often a choice of amounts to gamble. This will not only vary between sites and games but also within each game you often get a choice.
In slots there is often a selection of winning lines. You have to pick which winning line you would like to bet on. The more winning lines you pay for, the greater the odds of you actually getting a win. You may also find that if you want to have a chance of winning the jackpot, you will need to bet on all of the lines. This can add up to a lot of money.
In order to decide you need to consider several factors. The most important thing to think about to start with is the cost of the games. Calculate how much money you can afford to gamble and think about how many games you will be able to play with that money. It may be that you will be able to afford a lot of games, but you may have a tight budget and just be able to afford a few. Consider whether you are happy to pay out a lot of money per game and only pay for a few games and have a chance of winning the big jackpot or whether you would prefer your money to last longer, so you pay less per game but can only win small prizes.
The decision can be quite difficult. You have to weigh up whether you would get more pleasure from playing for longer or by giving yourself a chance of winning the jackpot but not playing for long. You may be prepared to take a lot of risk or rather not take so much and this will be a big influence in your decision as well.
How much you can afford to spend is a huge factor. It is surprising how many people do not think about this before they start playing. It is really important to make sure that you have enough money to pay for all of the things that you need so that you know that when you pay slots, you can afford to lose the money. Do not go in with the attitude that you will win money as the odds will be against you. It is far better to assume that you will lose and see any winnings as a bonus. If you do this, then you will not be so tempted to overspend. Consider that what you are paying out is for the fun of playing, it is not a way to make money. Casinos will always set up games so that they have a bigger chance of winning and therefore you are not likely to win.
How Are Gambling Sites Regulated In The UK?
What Makes a Responsible Bingo Site? |
Sixth generation (6G) underwater positioning technology from Sonardyne International. has been chosen by vessel owner and operator Companhia Brasileira de Offshore (CBO) to meet Brazil’s stringent new contracting specifications for subsea positioning.
The work equip the vessel’s inventory of Compatt 6 LBL transponders, with high specification DigiQuartz pressure sensors, was carried out at Sonardyne’s service, support and training centre in Macaé, Brazil. |
are encouraged to carefully review the full text of our Information & Conditions. Payment of deposit and/or final payment are an acknowledgement of receipt of these information & conditions and constitutes acceptance of such as outlined.Nexus Holidays departures are priced in British Pounds.
"Land Only" Package does not include the international flight.
Visa processing fee; international flights; optional travel insurance; gratuities to your tour guides, drivers and porters; items of personal nature such as laundry, room service, phone bills, excess baggage charges, optional tours, and all other items and/or services not specifically listed in the itinerary.
Tour prices listed are in Canadian dollars. Master Card, Visa, personal/company check, bank draft and electronic bank wire are all acceptable forms of payment. To take advantage of the "Cash Discount" rate you should pay the balance payment by checks or bank draft, payable to "Nexus Holidays".
A non-refundable deposit of £200 per person is required to secure your reservation. Reservation will not be confirmed until your deposit is cleared with our company. To secure a reservation on a trip departing within 60 days, full payment is required at the time of booking.
Transferring between tours (61 days or more) incurs a £100 per person administration fee plus any air/hotel/cruise/train ticket cost. Transfer fees must be paid at the time of change.
Reissue of airline tickets - from £200 per person (other fees may apply).
All claims against Nexus Holidays Inc. must be filed in writing within 30 days after completion of the tour. By utilizing the services of Nexus Holidays. you agree that the exclusive venue for all claims, actions or proceedings against Nexus Holidays. |
We offer dorms room with air-conditioner, fans, personal locker, electric heater for shower, and free wifi which features lots of sunlight, hangout areas and coffee shop underneath the hostel. Guests can feel free to mingle around with other travellers at the mini bar, and get free travel information from the connected travel agency next door. We also offer motorbike rentals for you to easily see the beautiful scenery of Ha Giang. |
Enter the chat room below and participate by either registering using your email or logging in as a guest user to remain anonymous. A place where they will be able to meet new friends in a friendly and safe environment. This room is highly moderated and inappropriate behavior will not be tolerated.
I have been coming here for four years a teen chat rooms, and I am still going to come here every day. Boys and girls are all welcome. Dolly I like talking to people who have the same interest as me. If you do not meet the age requirements you will go to another chat rooms site. This includes content protected by copyright such as music, articles, etc.
Inappropriate nicknames or conversation will NOT be tolerated. Keep an eye on what your children are doing. This place is really nice and you will meet all sorts of people plus it's free! In addition, you can talk in many topics concerning teenagers and share interests and hobbies, you can also discuss about problems that teens can be a teen chat rooms to it. I love the teen chat chat rooms! |
Amazing pizza! SO good that it must have some part of jesus in it. Just a bit at least. No good without the dipping sauce.
Dude, lets go to Twice the deal to get some jesus pizza.
Get a jesus pizza mug for your sister Beatrix. |
1 Sing vnto the Lord a newe song: sing vnto the Lord, all the earth.
2 Sing vnto the Lord, and prayse his Name: declare his saluation from day to day.
3 Declare his glory among all nations, and his wonders among all people.
4 For the Lord is great and much to be praysed: he is to be feared aboue all gods.
5 For all the gods of the people are idoles: but the Lord made the heauens.
6 Strength and glory are before him: power and beautie are in his Sanctuarie.
7 Giue vnto the Lord, ye families of the people: giue vnto the Lord glory and power.
8 Giue vnto the Lord the glory of his Name: bring an offering, and enter into his courtes.
9 Worship the Lord in the glorious Sanctuarie: tremble before him all the earth.
10 Say among the nations, The Lord reigneth: surely the world shalbe stable, and not moue, and he shall iudge the people in righteousnesse.
11 Let the heauens reioyce, and let the earth be glad: let the sea roare, and all that therein is.
13 Before the Lord: for he commeth, for he cometh to iudge the earth: he wil iudge the world with righteousnes, and the people in his trueth. |
Starting to really get into modelling having had the privilege of working with some great togs I have learnt alot. Still happily exploring what I am capable of as a model and enjoying the experience immensely.
I would describe myself as an english rose, I am a mature women but have soft features so tend to look younger than I am which is no bad thing! Voluptuous and at ease with my curves they are part of my character. 100% Natural no tatoos, but happy to wear fake ones if required too.
Love cosplay any excuse to get dressed up! I sometimes make my own accessories including jewellery which I also sell at craft fairs (perkypixie creations on facebook) I am really drawn to unusual some would say gothic, fantasy, romantic style photography.
For me I would like to do the more arty images that can draw you in and hold your attention. Anything a bit outside the box would consider doing futuristic looks too. Like most I am a multi layered character and the photographic projects I work on I would like to reflect that.
Happy to work TF or paid. I do not drive but willing to brave public transport for worthy projects. If shoots are some distance away i would have to ask for my travel expenses. |
This is the Windows 7 32bit Driver for the WMP54G Version 1 I hope everyone has the same happiness as I have!!!
You say this is the driver but you have not attached a driver so your post makes no sense.
How do I post the FILE to the driver?
I uploaded it like a million times?!!!!!
I take it you are trying to manually install a device driver to a device under Device Manager??
Download the driver and extract it to a folder.
Right click the device you wish to change the drivers for. You can select Properties > Driver > Driver Details to check you have the right device.
Hit OK, then Next and the driver(s) will then begin to install.
No Elmer, based on the repeated threads we've closed or deleted I now surmise that he's been trying to attach a file to a post.
laroccacory, first you need to make sure it is a supported forum file type such as .zip or .rar, second it must be small enough because each file type has a certain size limit (1.19mb for rar/zip). If your file is too big or unsupported then it is ignored.
If you feel the need to post something bigger than site limits then what you need to do is post it to a file hosting site and then post that link in your posting (unfortunately most of those sites delete your file after 60 days).
No Elmer, based on the repeated threads we've closed or deleted I now surmise that he's been trying to attach a file to a post.. |
Come Learn from THE FLEUR WREATH!
We will be hosting a floral watercolor workshop taught by Kendra Curtis, artist of @thefleurwreath. You will get step by step instruction on florals and botanical leaves along with a take-home watercolor art supply kit, your 11 by 14 inch painting from the workshop, and my art supply list. Come as you are, we will supply light refreshments and all the supplies. Let’s get painting! |
TORONTO, Dec. 19, 2018 (GLOBE NEWSWIRE) -- Wayland Group (CSE:WAYL) (75M.F) (MRRCF) (“Wayland” or the “Company”), a global, vertically integrated cultivator and processor of cannabis, today announced that its Board of Directors has initiated a process to explore a broad range of strategic alternatives, including, but not limited to assessing the potential spin-out and/or European listing of its international assets (the “International Assets”) in an effort to unlock the value of the Company’s vast international asset portfolio (a “Spinout Transaction”), as well as its underlying domestic Canadian assets. Any Spinout Transaction of the International Assets could include the Company’s European, Latin American, and Asia-Pacific operations.
The Company strongly believes in its current strategy; however, it does not believe its current share price accurately reflects the global portfolio Wayland has, and continues to create.
“We have demonstrated our capability in predicting future markets and working systematically to put supply chain in place, with some of the lowest transaction costs for international acquisitions in addition to organic growth and partnerships. Our exponential growth model has tremendous potential, as it is built on the solid foundation we have laid from five years of organizational learning as a licensed producer in Canada. This has allowed us to become one of five companies with EU-GMP certification on top of having all the requisite cultivation and processing licenses in Canada. It is time for us to capitalize on the largest future cannabis market in the world and focus our efforts in the wellness and medical markets to accomplish our vision of enhancing life through cannabis,” stated Ben Ward, CEO of Wayland.
Canaccord Genuity Corp. has been retained to serve as the Company’s financial advisor related to the strategic review process.
There can be no assurance the strategic review will result in the completion of any transaction or any other alternative. The Company has not set a timetable for completion of the review process, and it does not intend to comment further unless a specific transaction or alternative is approved by the Board of Directors, the review process is concluded, or it is otherwise determined that other disclosure is appropriate.
Wayland has several active initiatives in Germany that give the Company a distinct advantage in the German and European markets. The Company is the only organization in the world that has a facility ready for domestic cannabis cultivation. Located in Ebersbach, just outside of Dresden, the proposed facility gives Wayland 820,000 square feet of clean-room cultivation, processing, and extraction capabilities. It is currently being utilized to process industrial hemp from the Company’s adjacent 164-hectare hemp operation where the Company recently completed their first harvest yielding over 120,000 kg of dry hemp flowers. Once processed, the CBD distillate will be used for the Company’s recently launched nutraceutical business, MariPlant GmbH. Finally, the Company expects to receive their second EU-GMP certification for the Ebersbach facility in a matter of weeks, further strengthening Wayland’s medical production and distribution capabilities.
Wayland’s second European cultivation site is located in Regensdorf, Switzerland, a suburb of Zurich. The 60,000 square foot facility’s current production profile is approximately 2,000 kg of CBD flower per year. Wayland plans to upgrade this facility to bring it in line with the Company’s production standards from existing GACP standards and increase capacity to 14,000 kg per year with the goal of developing their own CBD products for sale throughout Switzerland and the rest of the European Union. Wayland will locate its Active Pharmaceutical Ingredients (API) manufacturing site for its global operations in Switzerland, taking advantage of existing phyto pharmaceutical talent in country.
Wayland has a definitive joint venture agreement with CBD Italian Factory S.S., a company of Group San Martino for the production of high quality cannabis products in Italy. The Company expects that the joint venture will marry the best of both entities with world-leading technology by Rockwell Automation paired with existing infrastructure in Piedmont, Italy, which includes agricultural expertise and biogas electricity. This will allow the sustainable production of quality CBD and THC products from a naturally derived fuel source. CBD Italian Factory S.S. and San Martino Group will bring mass-scale agricultural skills to the joint venture with a focus on local sustainable practices and expertise in Biomass Energy production. The Company holds 50.1 % of the joint venture while 49.9% is held by CBD Italian Factory, with Massimiliano Umberto Signorini assuming the role of CEO for the new company.
In July of 2018, Wayland’s application to Malta Enterprise to set up a business in Malta to manufacture finished dose medical cannabis was approved. Malta will offer the Company a unique advantage as Wayland will have the ability to import, extract, manufacture finished dose products, and distribute cannabis for medical purposes within Malta and the entire European Union. Malta Enterprise allows the Company to develop a wide variety of pharmaceutical products and export them across the European Union, and as Malta is a member of the EU, certain VAT tax are inapplicable to Malta Enterprise.
The Company has entered into an agreement to acquire a 51% stake in U.K. based Theros Pharma Ltd. (“Theros”), an early stage company that has successfully imported cannabis to the U.K. for patients with a prescription for medical cannabis. The company expects to be able to import cannabis to patients in the UK as early as March 2019.
Wayland has entered into an agreement to purchase 819 hectares of existing developed agriculture land in San Juan Province in Argentina, which is the ideal micro climate for cultivation. The properly has existing mass scale irrigation, using runoff from the Andes Mountains, and produces 1,000,000 kg of wine juice, and 400,000 kg of olives per year. Existing on site agronomists and farmers will take their knowledge of horticulture and apply it to Wayland’s existing world class system of cannabis cultivation. Outdoor cultivation will take place in existing alfalfa fields, to supply Wayland with low cost inputs. Initial extraction will take place in Argentina.
The Company has entered into an agreement to acquire 100% of the outstanding shares of Colma Pharmaceutical SAS (“Colma”), a licensed producer of THC cannabis in Colombia, holding four licenses for cultivation and processing on a leased premise in Ibaque, Colombia. Wayland plans to cultivate THC cannabis outdoor and year-round with an infrastructure investment including 415,000 square feet of processing and clone and vegetation greenhouse facilities to support outdoor cannabis flower production of 125 hectares.
Wayland has entered into an agreement to acquire 50.1% of Tropicann Pty Ltd. (“Tropicann”), a privately owned Australian company located in Darwin, Northern Territory. It plans to build an outdoor grow facility to take advantage of the ideal cannabis cultivation climate with minimal environmental impact. The Company believes it can leverage a major port in Darwin that will provide access to major APAC markets.
The Company’s flagship facility is located in Langton, Ontario with cultivation, extraction, formulation, and distribution capabilities. The facility is a purpose-built cannabis production facility with an emphasis on automation and energy efficiencies. The Company partnered with Rockwell Automation to develop a fully automated system including the development of AI Data Grow, the Company’s artificially intelligent master grower. This allows Wayland to drastically reduce its cultivation labour needs by approximately 90% of the industry average while also mitigating risks associated with infecting crops. The facility will be completed in two phases, the first of which is approximately 225,000 square feet in size with 90,000 square feet of production and office space and approximately 135,000 square feet of grow space which will yield the Company approximately 65,000 kg of dried cannabis flower per year. Phase two will bring an additional 719,000 square feet of grow space online taking production capacity much greater than 100,000 kg per year.
Wayland’s Langton campus has been certified by the European Medicines Agency after receiving the certification of EU-Good Manufacturing Practices (“EU-GMP”). EU-GMP certification allowed Wayland to sign the largest ever medical cannabis export deal with Cannamedical of Germany, agreeing to provide the medical cannabis distributor with a minimum of 9,000 kg of product over a three-year period. Wayland is one of only five cannabis companies in the world to receive the EU-GMP designation which is another advantage the Company believes it has in the global medical cannabis arena as demonstrated by this large purchase order.
Manitoba: Supply agreement with the Manitoba Liquor & Lotteries Corporation (“MBLL”) to make available for purchase by MBLL at least 550kg of various cannabis products during the first twelve months of the agreement.
Alberta: Supply Agreement with the Alberta Gaming, Liquor & Cannabis Commission (“AGLC”) to allocate up to 3,375kg of cannabis product for the Alberta market within the first six months.
British Columbia: Through a memorandum of understanding (“MOU”), Wayland is a preferred licensed producer to the BC Liquor Distribution Branch (“BCLDB”) to initially supply approximately 3,622kg of non-medical cannabis to BCLDB over the first 12 months following legalization.
Ontario: Selected by The Ontario Cannabis Store (“OCS”) to supply a variety of safe, high quality cannabis products through its online store since launching October 17, 2018.
The Company has taken a purposeful and consumer-centric approach to each of its brands/offerings, each validated and optimized with local consumer research. Strains within each portfolio will match brand positioning and satisfy target consumer needs and benefits.
Solara C: Designed for the modern, active consumer who is looking to find solutions to help them live healthier/better without using stronger pharmaceutical alternatives. This brand will be CBD-only and create a wide range of products from beverages to topical creams with the expressed purpose of promoting a healthy, balanced lifestyle.
Kiwi: Designed for light users who are new to the category and looking to better understand Cannabis and its effects. The brand will exist to simplify and make the cannabis experience more welcoming and approachable to the masses.
Northern Harvest: Designed for light / medium users who enjoy Cannabis as part of their active and social lives. The brand will exist to promote a more natural and balanced approach to Cannabis with a focus on providing a fun and lighthearted experience.
High Tide: Designed for medium to heavy users who enjoy the cerebral effects of Cannabis. This brand will produce high quality, high THC cannabis with the expressed purpose of pushing the limits of the THC experience.
Lost at Seed: Designed for medium to heavy users who want only the best Cannabis money can buy. This brand will provide highly desirable and impossible to find strains only available on a limited assortment basis.
Rare Dankness: This partner brand will be for experienced Cannabis users who are knowledgeable about strains, potencies and profiles. It will offer a wide selection of premium award-winning strains that users won’t be able to find anywhere else.
Wayland is a vertically integrated cultivator and processor of cannabis. The Company was founded in 2013 and is based in Burlington, Ontario, Canada and Munich, Germany, with production facilities in Langton, Ontario where it operates a cannabis cultivation, extraction, formulation, and distribution business under federal licenses from the Government of Canada. The Company also has production operations in Dresden, Saxony, Germany, Regensdorf, Switzerland, Allesandria, Piedmont, Italy, Ibague, Colombia, London, UK, Australia, and Argentina. Wayland will continue to pursue new opportunities globally in its effort to enhance lives through cannabis.
This news release includes forward-looking information and statements, which may include, but are not limited to, information and statements regarding or inferring the future business, operations, financial performance, prospects, and other plans, intentions, expectations, estimates, and beliefs of the Company. Such statements include statements regarding the Company's plans for its operations in all regions, proposed acquisitions, the Company’s continued global expansion, its effect on the Company’s global platform and the Spinout Transaction. Forward-looking information and statements involve and are subject to assumptions and known and unknown risks, uncertainties, and other factors which may cause actual events, results, performance, or achievements of the Company to be materially different from future events, results, performance, and achievements expressed or implied by forward-looking information and statements herein. Such assumptions, risks, uncertainties and other factors include, but are not limited to, that the proposed transactions will be completed on the terms and timelines anticipated by the Company or at all, the effect that the proposed transactions, and Spinout Transaction if and when completed, will have on the Company’s global platform, that all necessary stock exchange, regulatory and other approvals will be received in connection with the proposed transactions and or the Spinout Transaction. Although the Company believes that any forward-looking information and statements herein are reasonable, in light of the use of assumptions and the significant risks and uncertainties inherent in such information and statements, there can be no assurance that any such forward-looking information and statements will prove to be accurate, and accordingly readers are advised to rely on their own evaluation of such risks and uncertainties and should not place undue reliance upon such forward-looking information and statements. Any forward-looking information and statements herein are made as of the date hereof, and except as required by applicable laws, the Company assumes no obligation and disclaims any intention to update or revise any forward-looking information and statements herein or to update the reasons that actual events or results could or do differ from those projected in any forward looking information and statements herein, whether as a result of new information, future events or results, or otherwise, except as required by applicable laws. The Canadian Securities Exchange has not reviewed, approved or disapproved the content of this news release. |
ISPs in Singapore are offering 2Gbps broadband connection. We are using CCR1009 to archive 2Gbps NAT traffic to a single host in LAN.
hotspot central login. SNS,Youtube login. |
My phone went off early this morning at 6.30 and I leapt out of bed in a panic thinking immediately of the worst, that something had happened to my mother.
Only once I reached the phone, answered it and it had stopped ringing did I realise I had set the alarm the night before and my mother was most likely okay, but even then I could not return to sleep.
I am living in a strange time, this hovering on the edge between life and death, my mother’s life and death, and wondering when it might happen. My husband is away and I am holding the fort or so it seems, which adds to the surreal tensions that envelope me everyday.
A few days ago I received a letter from an old friend, a woman whom I shall name Cate, who now lives in country Victoria. I did not recognise her name on the envelope at first because Cate now travels under the name of her third husband. But as I began to read her letter pennies began to drop into place.
She is sorry, Cate writes, to have lost contact with us, with my husband and me, but she had imagined at the time of her separation from her second husband that we were ‘on his side’.
How strange I thought reading this and remembering back to that time. I did not enjoy Cate’s second husband at all, and I was not so much sad as surprised when they separated.
I have a soft spot for Cate. It was she who in a sense brought my husband and me together all those years ago.
I once worked alongside Cate in the days when I was a newly graduated social worker. One Saturday evening Cate held a dinner party – dinner parties were fashionable in those days – and through a long and complicated series of manoeuvres, my husband and I wound up together at the dinner table.
In a sense we have not been apart since. Though do not imagine it has always been a honeymoon but a productive union nevertheless, and Cate believes she was responsible for beginning it, as indeed in some ways she was.
I have not seen Cate now for some fifteen or maybe more years. We ran into her, shopping in Safeway, one Saturday afternoon. She seemed distant at the time and I remember wondering at her coyness in introducing us to her new man, J, whom she eventually married.
J, Cate writes, died two years ago, but not before she had nursed him for six years. She refers to him in her letter as ‘beloved J’, so presumably this third marriage was a successful one.
Cate needs our help, she writes in her letter. Could we do her a favour? She turns seventy soon and although she does not imagine she will die in the next little while, anything is possible. For long and complicated reasons, which she does not go into, Cate has lost touch with her children, all three of them, two daughters and a son, children who must by now be aged in their mid to late forties.
Could we please help? Cate asks. Could we ‘discreetly’ and ‘sensitively’ make contact with her children and let them know that she loves them and would like at least to have an address for them.
Cate’s solicitor has told her there is no point in listing her children in her will if she has no contact address for any of them.
Cate would love to see her children, she writes, if they are willing, but she does not expect them to come running. She wants only to know how they are going and would hate for them to be left full regret after her death.
I rang a friend who might have known a contact address for at least one of these children but she too has lost touch and suggested I ring the first ex husband, a distant and mutual friend, who lives in Melbourne.
It gets sticky and tricky here. I am fearful of how Cate’s ex husband might respond were I to ring out of the blue and put in a request to him for a phone number for his children in order to enable them to resume contact with their estranged mother if they should wish.
‘I have not always been the best of mothers,’ Cate writes.
Which one of us has? I think.
This other friend who has also lost contact with Cate’s children and advises me to ask the first ex husband, warns me that Cate is ‘manipulative’.
I know the word well. It is a feature I have detected in myself. I inherited it from my mother, a state of mind that says you dare not ask for something directly, you can only safely work your way around to getting someone to give you something or do something for you, by stealth.
I try not to get into manipulations these days. To me the tendency to manipulate is the tendency of a weak person who lacks in confidence sufficient to cope with the consequences of a direct question, whether positive or negative.
I suspect women of my mother’s generation were more heavily into manipulation than today because before the advent of feminism and the beginnings of a deeper awareness of the rights of women, at least in western culture, they could only get what they wanted by stealth or feminine guile.
It would not have done for a woman of my mother’s generation to be to open with her desires. She would have needed to obscure them, perhaps even from herself.
Good luck with the problems that Cate's request poses.
I don't think you should assist in this way. If she wishes to make peace she should do it herself. Any half decent detective could find them pretty easily.
As to the will she can simply list their names and direct the executor to search for for them dutifully.
I showed your post to my husband and he said, "Has Cate looked up her kids on Facebook and tried to friend them?"
Respectful decline Cates request as it could get real messy and ugly. You could get stuck right in the middle of a family dispute, believe it's not a nice place to be :-).
I'm not sure if you're asking, but I would hesitate to get involved under the circumstances.
So far there are no problems with Cate's request, though it's early days, Elephant's Child. On the other hand, as you suggest, self deception can be dangerous. Thanks.
Glenn above is on-the-button: Facebook of course.
And I agree with Antares above as well. this whole thing smells.
Cate needs to at least MENTION her children, each by name, in her Will.
A person who is mentioned in a Will, cannot contest it, as the mention indicates they were properly in the thoughts of the author.
You're not the first to suggest I should not help out here, Laoch, though I feel inclined to at least let it be known that this mother is trying to contact her children. Beyond that I'll do nothing.
We all manipulate. We manipulate with reason as much as we do with emotion but the emotional manipulators usually get the most flack. I would suspect that, of the two, it is the most common as not everyone is capable of intellectual reasoning to that level but I don’t think one is worse than another; it all depends on intent. Either way it’s easy to see people who try and get us to do things we would rather not do as aggressors.
My daughter says of me, “You do good guilt,” by which she means I know exactly what buttons to press with her. And I do. Like me she has a natural propensity to feel guilt and so it take no great skill and very little effort to make her feel guilty; it’s bubbling under the lid anyway. And so I have to tread carefully. She expects to get an Upper Second Class Honours for her Psychology Degree and I’m proud of her because she’ll have done that whilst holding down a fulltime job. A 2:1 is good, but it’s not a First. And she knows it. So I don’t know if my eyes gave me away or what – you can do so little about body language – but I did my best to be genuinely pleased. And I am. I think I am. I don’t know what I am.
Although I “do good guilt” I’m not sure that I abuse that power. If I want people to do things I’m more likely to reason with them. I manipulate with logic but I don’t feel so bad about that. I trust reason; reason is honest. Emotions an notoriously unreliable. I’ve seen some very dirty fighters though and it does tend to be women but I guess that’s because they lack physical power or feel they don’t have a position of equal authority in the family and so they resort to “underhanded” methods. My mother most certainly did, or tried to do. But of course a manipulator is only effective if they know their target’s triggers. My mother would send me to Coventry (give me the silent treatment) for days and it had no effect on me whatsoever. It should have had but I knew I could last longer than she could. The same happened at work once. For some reason I crossed a picket line (not like me to be so principled) and my group ostracised me. Several weeks later my boss approached me on their behalf wanting to put an end to all hostilities. I’d worn them down, not the other way round.
This doesn’t mean that I’m not susceptible to being manipulated because for years I allowed my father to do exactly that. He used religion as his implement of choice. Most bullies have their gangs just in case they’re not intimidating on their own and most thugs will have a heavy standing at their shoulder. And they don’t get heavier that God Almighty. He didn’t need to scream, rant or rave or hold his breath until he turned blue. All he had to say was, “Well, God says…” and I didn’t have a leg to stand on.
I think most of the time though the kind of person you’re talking about in your post rely on people’s good natures. We judge ourselves if we turn them away. It’s very clever, isn’t it? We become our own bully. Of course helping someone else makes us feel good about ourselves even (or maybe especially) if they don’t deserve our help so as long as we’re getting something out of the deal then go for it but once they begin to become a drain, that’s the time to call a halt. And be firm.
I'm not sure of the likelihood that Cate would be on Face Book, Glenn. Maybe we're a bit behind here in Australia but many of the folks I know aged over forty won't have a bar of it, but it's otherwise a good idea.
I don't fancy getting stuck in the middle of an ugly family dispute, Windsmoke, especially when it's not my own family, but somehow I think that's unlikely to happen.
So many folks advising me to take care here, Antares. you too.
Thanks for the warning but I don't think it's as dire as I perhaps made it sound.
Hmmm… bit funny that the lawyer could not track down NOK without an address.
The will I suspect is subterfuge, AnnODyne.
I think Cate wants to make contact with her children. I can understand that.
I can also understand that something's gone wrong along the way and those kids might elect to continue to avoid her, but it might help for them to know that they are still in their mother's thoughts, whatever that might mean.
Has she tried the obvious things like the phone book or just googling their names?
I suspect those kids don't want to be contacted as they are old enough to have made the move themselves if they wanted to. However, that is beside the point. I think as long as you don't get drawn into the family drama, then go ahead and make that first contact. Perhaps the olive branch she offers might be accepted – and that would be something good to hold on to.
Once upon a time I would have called the ex and asked for contact details. Now I would pass the ex's number on to cate. If she really wants to know, she will call him. He might even welcome the call after such a long 'cooling off' period!
A lawyer (I'm assuming that what a soliciter is. If not, please correct me) advising Cate to leave her kids out of the will because she doesn't know their address just doesn't ring true to me. I think she made the story up and is just afraid that if she contacts the children herself, she'll be rejected. I personally would stay out of it, but that's probably due to a flaw in my own character. If you're confident this isn't all going to blow up in your face, and you still have fond feelings for Cate, then, by all means, go ahead.
If I were you, I would suggest to 'Cate' that she ask her lawyer to find the children. Most lawyers and law firms use investigators who do just this kind of thing. It usually takes a day or two. Once done, she can get in touch. There are also specialists who can advise her about making contact, etc.
It's her responsibility, right? You can support her efforts but not do what she should do for herself.
I don't know how to suggest this delicately, and I hope you will understand what I am saying. Could you be more apt to go to Cate's rescue (she's asked you to do more than just contact them — she wants you to smooth things over) as a way to avoid dealing with what must be very difficult feelings & thoughts about your mother dying? I think the situation with Cate could be potentially very draining and therefore harmful to you at a time when you might need to conserve your energies for your own things. It sounds like the kind of situation that could snowball into something much bigger very quickly. You're a kind, generous person. Be so to yourself, too. And take care.
This out of my realm to offer any good solutions. Go with your guts Elisabeth on what you think is best and what you would like to do for Cate. I know she could and should have done this herself but even if you want to try to help, it is not really wrong.
This is just sad and puts you in an awkward position.
If the prospect of an inheritance won't flush them out nothing will.
I tried to Google the next of kin, Christine and it wasn't easy. The family name is commonplace and the two daughters are likely to have changed theirs while the son lives overseas and is out of touch with both parents.
It would take something more I suspect to track down these children, who may yet not want to be located.
I assume Cate's tried those things, Marie, though as I said to Christine earlier I tried, too, without success.
It's most likely that the kids don't want to be contacted but I think an olive branch or two might help and if not, so be it.
I hope I don't end up in the 'discard pile', Steven, but my contact with these people in recent years is very limited and it will not be too upsetting if no one wants to make contact with me anymore, though I can't see why they would dish me.
I am merely the messenger and I'm offering a brief and indirect message and then bowing out.
I almost lost track of your wonderful comment, Jim, but found it again just now.
I know all about doing a guilt trip on my children, I do it from time to time and always try to drag myself and them back out of the morass of such awful pressurizing.
My mother did it to me, too.
'I didn't think "you'd" be like that,' she'd say. 'The others yes, but not you.' In others words: my little girl is a good girl, she'd never do anything like that, namely anything I would not expect of her.
Our emotions guide us into deciding how best to react, if we can exoerience first and then think about them.
Without emotions we are in trouble. There are countless examples of psychopaths and sociopaths who are fantastic at reasoning, and all their arguments might make sense at the level of logic but they are devoid of feeling and are therefore dangerous.
Emotions distinguish us from the robotic, or to some extent from animals, though my hunch is that animals can feel more than we often recognise.
I'd agree, Stafford, but I suspect Cate knows her ex's number but is too fearful to call him, even with time there's still all that water under the bridge.
I have since spoken to the Cate's ex and he has assured me he will pass on the message to his children, the two with whom he still has contact and presumably he suggests they will want to talk to me. We shall see. If they don't make contact, I'll leave it there.
Lawyers and solicitors are one and the same here, Kirk and yes, I agree I think the lawyer story might be not entirely accurate, but it may have been a trigger to resume contact.
Something has happened to cause Cate to write such a long letter after all this time. I doubt that it's malicious.
I hope that's not too Pollyana-ish of me.
Maybe this happens a lot in your part of the world, Mim. I'm not sure, but here as far as i know lawyers tend to expect more of their clients.
A private investigator might do the job for a price but people here, as far as I know are reluctant to appoint detectives. They'll go through friends first.
Please don't worry too much about me, Lynn. I'm not planing on getting myself embroiled in other people's messes. You're right i have enough of my own.
A phone call is about the extent of it. In fact I've made the call and if the children don't get back to me as a consequence, I'll leave it there. I'll write Cate a latter and tell her there's nothing more I can do.
I have gone with my guts Fazlisa and so far nothing dreadful has happened nor do I expect it will.
It'd be good if something good could come out of it but I'm not counting my chickens, as the saying goes.
It has felt an awkward position, Mami and it is very very sad, but as everyone here suggests, it's not for me to intervene beyond a minimal response if necessary. The sadness is for this other estranged family.
I'm not so sure that it will be much of an inheritance, RH, at least not literally, though there might be other, and to my way of thinking better rewards out of resuming contact, but not if people feel too hurt and bitter or if they are too damaged.
What's a better reward than money?
Where do you live, Mars?
In your terms I probably live on Mars RH, and here I can't but quote from Oscar Wilde who wrote words to the effect that 'the cynic knows the price of everything and the value of nothing'.
There are things worth more than money. |
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Since the 1960s, the two groups that historically have developed vaccine guidelines for the United States have been the Advisory Committee on Immunization Practices (ACIP) and the Committee on Infectious Diseases of the American Academy of Pediatrics (AAP). During 1994, these organizations participated in a working group that included representatives from the American Academy of Family Physicians to develop one vaccination schedule that would accommodate the current ACIP and AAP recommendations and ensure the earliest administration of vaccines. The recommended childhood immunization schedule Table_1 has been endorsed by these groups and becomes effective January 1995.
In the first year of life, three doses each of diphtheria and tetanus toxoids and pertussis vaccine (DTP), Haemophilus influenzae type b (Hib) vaccine, and oral poliovirus vaccine (OPV) are recommended to be administered at ages 2, 4, and 6 months; however, the third dose of OPV may be administered through age 18 months, and for children who receive Haemophilus b conjugate vaccine (Meningococcal Protein Conjugate) (PRP-OMP) at ages 2 and 4 months, a dose at age 6 months is not required. For hepatitis B vaccine, the first dose is recommended at birth (but can be given up to age 2 months), the second at age 2 months (age 1-4 months is acceptable, provided at least 1 month has elapsed since receipt of the first dose), and the third at age 6- 18 months. Vaccines recommended at age 12-15 months can be administered simultaneously during one visit or during two separate visits. The second dose of measles, mumps, and rubella vaccine (MMR) may be given at entry to kindergarten or middle school. Diphtheria and tetanus toxoids (Td) is recommended at age 11-12 years but may be given through age 14- 16 years. When this vaccine is given at age 11-12 years, health-care providers can ensure that the child has received a second dose of MMR. Reported by: Advisory Committee on Immunization Practices. American Academy of Pediatrics. American Academy of Family Physicians. National Immunization Program, CDC.
indicate range of acceptable ages for vaccination.
at either one or two visits.
HBsAg during an early prenatal visit.
>=15 months and may be preferred for these doses in children in this age group.
received PRP-OMP at 2 and 4 months of age do not require a dose at 6 months of age.
conjugate vaccine may be used as a booster dose at age 12-15 months.
4-6 years of age OR at 11-12 years of age.
and American Academy of Family Physicians. |
Sandwich elements with polystyrene core!
The extremely light sandwich elements can be processed easily using conventional machines (bevelling, veneering).
Individual shaping is problem-free particularly due to the large board formats.
We also provide versions with frames. |
These ceramics come in a variety of colors, which are designed to mix and match. Each piece has a base made of red earth from Ootani which is then hand signed.
Made in Tokushima - one of the oldest areas in Japan which is dedicated to the the art of ceramics.
All Sueki ceramics come packaged in a handmade box. |
International growth roadmap - a clear plan that secures more efficiency by defining priority products and countries, market entry models, partner criteria, etc.
Products/services which are most suitable for export.
An overview of countries, including a ranking of country attractiveness.
Concrete advice how to reach your foreign customers.
Points of attention for your organization to ensure that exports can boost your business successfully.
We start with a brainstorm session with you before we execute relevant research.
Which product or service is the most suitable for export?
Which country is most suitable for my product or service?
What is the best market entry strategy?
Is our internal organization ready for internationalization? |
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In our last Community Broadband Bits podcast, Christopher and I discussed the August 10th U.S. Court of Appeals for the Sixth Circuit decision to reverse the FCC’s February 2015 ruling against state barriers. We mentioned Harold Feld’s article about the ruling posted on his website. In keeping with most matters of importance in the municipal Internet network field, Harold expertly sums up the history of the case, the arguments, and what the outcome could mean for the future.
Feld gets down into the crux of the argument that won over the three judges in the Sixth Circuit - the need to establish if it is states or federal agencies that make the decisions regarding whether or not local governments can provide telecommunications.
Determining the answer was a multi-step process and Feld explains how the FCC came to the conclusion that they had the authority to preempt the laws and the states' arguments against it. This was, after all, a test case and Feld describes why the FCC chose Chattanooga and Wilson.
As with most things worth doing in policy land, it’s disheartening that it’s an uphill fight to get to rational policy. The idea that states should tell local people in local communities that they can’t invest in their own local infrastructure runs against traditional Republican ideas about small government and local control as it does against traditional Democratic ideas about the responsibility of government to provide basic services and promote competition. But that’s how things work in public policy sometimes. We can either give up and take what we get, or keep pushing until we change things for the better.
It has been several weeks, but Lisa and I wanted to answer any lingering questions people may have about the results of the Sixth Circuit case reviewing the FCC's action to remove state-created barriers to municipal networks. We devoted Community Broadband Bits episode 217 to the case and aftermath.
The Sixth Circuit ruled against the FCC narrowly - finding that while it had no dispute with the FCC's characterization of municipal networks as beneficial, Congress had not given the FCC the power to overrule state management of its subdivisions (cities). As we have often said, restricting local authority in this manner may be stupid, but states are allowed to do stupid things (especially when powerful companies like AT&T and Comcast urge them to).
Lisa and I explore the decision and explain why we are nonetheless glad that FCC Chairman Tom Wheeler and Commissioners Rosenworcel and Clyburn moved on the petitions from Chattanooga and Wilson to remove state barriers to next-generation network investment. We also reference this blog post from Harold Feld, which is a well-done summary of the situation.
The Sixth Circuit Court of Appeals issued their order on August 10th supporting the states of Tennessee and North Carolina in their challenge from an FCC decision from February 2015. Both states objected to the FCC’s decision to preempt state laws preventing municipalities from providing fast, affordable, reliable connectivity via municipal Internet networks. The Appellate Court Judges reviewed the legal arguments, the precedent, and the interplay between federal authority and state sovereignty.
The impact of their ruling will affect more than a few pages in a law school text book. Access to high-quality Internet access positively impacts real people and businesses and, as Cecila Kang captures in her recent article in the New York Times, the people who depend on it fear the outcome if their state legislators take it away.
“We’re very worried because there is no way we could run this equipment on the internet service we used to have, and we can’t imagine the loss we’ll have to the business,” said Charlotte Vick, head of sales for the farm.
As Kang notes in her article, the FCC has no plans to appeal the decision, so battles will resume at the state level. Advocates will need to be twice as vigilant because incumbents - the only ones that come out ahead from this decision - may try to push state legislators for even tougher anti-competitive state barriers.
EPB customers love the fast, affordable, reliable Internet access they get from their muni and they appreciate the way its smart-grid helps them save money on their electric bill. According to a new J.D. Power report, their municipal utility is also the highest rated mid-size utility in the South for customer service and reliability.
Just a month ago, Consumer Reports magazine rated EPB the best TV and Internet access utility in the county for customer satisfaction, as chosen by a reader survey. The J.D. Power report went on to rank EPB number two in the country in the category of municipal or investor-owned electric utility.
The Times Free Press reports that in 2015 EPB Fiber Optics earned a net income of $23.5 million while the electric division earned $3.5 million. EPB President David Wade said that the smart-grid has reduced power outages by 60 percent and contributed to customer satisfaction by enhancing reliability of the system.
"The lesson that utilities can learn from other high-performing service providers is that to excel you need a culture that puts customers and employees first," said John Hazen, senior director of the utility practice at J.D. Power. "And because customer expectations continue to increase, you need to have a mindset of continuous improvement to keep up."
EPB Chairman Joe Ferguson said the favorable grades from EPB customers reflect the utility's local ownership, public service and management focus on serving the customer.
Minneapolis, MN - The 6th Circuit Court of Appeals decided today to dismiss the FCC's February 2015 decision to encourage Internet investment in Tennessee and North Carolina. Tennessee and North Carolina had both restricted local authority to build competitive networks.
"We're disappointed that the FCC's efforts to ensure local Internet choice have been struck down," says Christopher Mitchell with the Institute for Local Self-Reliance. "We thank the FCC for working so hard to fight for local authority and we hope that states themselves will recognize the folly of defending big cable and telephone monopolies and remove these barriers to local investment. Communities desperately need these connections and must be able to decide for themselves how to ensure residents and businesses have high quality Internet access."
ILSR and Next Century Cities filed an Amicus brief in support of the FCC's position. View the Court's Opinion here.
Disappointing news from the U.S. Sixth Circuit Court of Appeals today as the Court chooses to reverse the FCC’s February 2015 preemption order that peeled back restrictive state laws in Tennessee and North Carolina. We have the opinion for you to download and review. You can also view the decision at the Sixth Circuit's website.
We consider the Sixth Circuit’s decision disappointing, incorrect, and we hope the FCC and the cities of Chattanooga and Wilson appeal this decision. Local connectivity and telecommunications should be determined by the people who will be affected by their own decisions, not by officials who are distant, unaware of local matters, and lobbied by rich corporate Internet Service Providers with an interest in limiting competition.
In their statement, Next Century Cities, who joined us in filing an Amicus Brief, said, "Today’s court ruling is a setback in the fight to ensure access to next-generation broadband for more Americans, and Next Century Cities is disappointed by this decision."
“Today’s ruling doesn’t change the fact that these laws were hurting communities in Tennessee and North Carolina. They were written by telecom industry lobbyists to protect incumbents like AT&T and Comcast from competition. Similar laws exist in other states, and they all need to go. State legislatures should repeal these laws and replace them with ones that promote competition and consumer choice.
The results of a statewide Tennessee survey on residential and business connectivity are in and they ain't pretty. Thirteen percent of the state - more than 834,000 people - don’t have access to 25 Megabits per second (Mbps) download and 3 Mbps upload, which is the FCC's definition of broadband. Authors of the study make a number of recommendations, the first of which is removing state barriers that stifle Internet infrastructure investment.
"...A More Open Regulatory Environment"
The study, commissioned by the state’s Department of Economic and Community Development (TNECD) earlier this year, includes feedback from more than 23,000 households and businesses.
The State of Tennessee could consider lifting administrative burdens and restrictions to broadband infrastructure investment to fostering a more open regulatory environment.
In the report, the authors provide detailed reasoning for why the state should embrace an open regulatory environment to encourage competition. They note that state barriers impact electric cooperatives, municipalities that operate electric utilities and cannot expand beyond their own service areas, and municipalities that do not operate electric utilities but can only build telecommunications infrastructure in unserved areas with a private partner.
The FCC came to the same conclusion in February 2015 and rolled back Tennessee state laws in order to encourage competition. Tennessee is leading the charge against the FCC's decision with North Carolina (even though NC's Attorney General criticized the law). The parties have filed briefs, attorneys have presented oral arguments, and now the Sixth Circuit Court of Appeals is considering the case. |
This extremely sweet Nike Air Max 1 WMNS Hyperfuse Premium edition is going to be an instant hit. It has to be. Women like these sweet colors and they likely have to be really strong, nót to get there wallets out for these beauties.
Nike surely has a great trendwatcher at there service, because no one could have predicted this trend as good as this one. On the catwalk of the biggest fashion houses we saw bright colors combined with each others. They call it ‘colorblocking’. And also soft pastel shades were combined together or with those colorblocking shades. So the designers of the Nike Air Max 1 thought: lets combine those trends into once perfect shoe. And thats how the Nike Air Max 1 Hyperfuse Premium Hyper Blue Total Crimson was born. This shoe will be released in juni 2013 so make sure you make a note of that. Because we can imagine this shoe will sell like hot cakes over the counter.
This Nike Air Max One Premium Hyperfuse collection has, next to the normal Nike AM1 elementes, also some Air Max ‘90’ and some 97’ looks to it. This shoe has a white mid-sole and a dark blue rubber sole. This shade of blue is also used for the laces. Around the shoe you see a path of soft peach leather and also some light blue leather. The air-bubble in the mid-sole is orange, so this main color keeps coming back. |
MEMPHIS, Tenn. – The U.S. cotton industry is pleased with passage of the Tax Cuts and Jobs Act (H.R. 1) – legislation it supported that can spur economic growth by 1) lowering taxes and 2) simplifying the code for America’s cotton producers and associated businesses.
National Cotton Council (NCC) President/CEO Gary Adams wrote to Senate Majority Leader Mitch McConnell (R-KY) and House Speaker Paul Ryan (R-WI) thanking them for crafting and for shepherding through Congress a bill that will allow farm families to further invest in their operations and preserve that farm for future generations by allowing full and immediate expensing of capital purchases and doubling the estate tax exemption.
Adams also noted that U.S. cotton producers continue to face low prices and high input costs while lacking an adequate farm bill safety net. As a result, a number of family cotton farms and other cotton businesses have been lost in recent years.
The NCC is U.S. cotton’s central organization, and its members include producers, ginners, cottonseed processors and merchandizers, merchants, marketing cooperatives, warehousers, and textile manufacturers. Farms and businesses directly involved in the production, distribution and processing of cotton employ more than 125,000 workers and produce direct business revenue of more than $21 billion. Accounting for the ripple effect of cotton through the broader economy, direct and indirect employment surpasses 280,000 workers with economic activity of almost $100 billion. |
Baseluos Law Firm (BLF) does represent clients in San Antonio misdemeanor criminal defense cases in Bexar County and surrounding counties. The firm is very aggressive in pursuing all available defenses against a myriad of alleged crimes including DWI, theft, trespassing, and drug offenses. The attorney will interview the client immediately in the course of representation, and we will seek to obtain all information in the District Attorney's file.
From there, the law firm explores all options. We will never tell a client to accept a plea. The bottom line is that a criminal defense attorney must be willing to take a case to trial. Otherwise, prosecutors become very smart at figuring out the defense attorney who is bluffing. Prosecutors who sense fear are less likely to compromise on parameters with wide ranges such as fines, probation time, and downgrading of Class A and Class B misdemeanors.
No one is above being wrongfully prosecuted - it happens all the time. What you need to know to give your criminal defense attorney a fighting chance is the following Criminal Bill of Rights. Keep this language on a piece of paper in your wallet and refer to it any time you are stopped.
My lawyer has told me NOT to talk to anyone about my case, NOT to answer questions, and NOT to reply to accusations.
I REFUSE TO CONSENT TO ANY SEARCH.
Call my lawyer if you want to ask me any questions, search me or my property, or do any tests or other ID procedures.
I DO NOT WAIVE ANY OF MY CONSTITUTIONAL RIGHTS.
Do you know how many accused people fail to follow the simple instructions above ? They talk to people about their case, specifically the arresting officer. They answer questions posed them by legal authorities and they reply to accusations.
They unwittingly consent to searches despite their constitutional right to refuse. They take tests not knowing that such tests are designed to enhance the appearance of guilt.
Perhaps there is a little part in all of us that thinks, “Well, if I just do what they tell me, then they shall see it as one big mistake and let me go.” Unfortunately, that is wrong.
For example, when an officer tells you, "Ok, just between you and me, do you think you have had too much to drink?" , what the officer neglects to tell you is that there is a camera and voice recorder that is recording everything including what you say. There is no such thing as "Just between you and me".
The officer is certainly not your friend. From the moment he comes into contact with you, his objective is to build a case for the Bexar County and greater San Antonio Texas District Attorney to file against you. Period. The more you talk and the more you move around allow the officer to do just that.
If you have been charged with a criminal offense in Bexar County or San Antonio, you must contact a San Antonio Bexar County criminal defense attorney immediately. |
Watkins Ad Products, established in 1998, is a full line distributor of promotional advertising products, custom message apparel and corporate gifts, and provides embroidery amd screen printing on a wide range of merchandise. Our company offers unique advertising services for businesses, churches, resorts, civic organizations and political candidates, as well as golf tournaments and family reunions. We supply schools, athletic teams, cheerleaders, bands, booster clubs, and other organizations with all their fundraising and school spirit items. A well-stocked showroom is maintained with sample products, catalogs, and special sales brochures to spark the imagination. As you browse our website, you'll discover an array of products designed to get your business noticed in your marketplace. You'll uncover a wealth of innovative items throughout the thousands of manufacturers and brands that we represent.
Creative services include designing company logos, T-shirt designs, and supplying custom artwork for clients. Our goal is to assist you, our customer, in achieving the special image that you're looking for --- we help you stand out from your competition! Our staff of professionals is committed to providing outstanding customer service, timely delivery, meticulous attention to detail and SATISFACTION GUARANTEED. We strive to help our customers succeed by offering high-quality products at the best possible price. WATKINS AD PRODUCTS IS YOUR COMPLETE SOURCE FOR PROMOTIONAL ADVERTISING. We look forward to working with you! |
Gary Hart is a California native who has been exploring the Golden State’s landscapes with his camera for his entire adult life. Before becoming a full-time nature photographer about fifteen years ago, Gary made his living as a writer. Now he enjoys sharing his knowledge and experience in photo workshops in some of the world’s most beautiful locations, and educating photographers with his regular blog and many articles in “Outdoor Photographer” magazine.
Gary offers photo workshops in Yosemite (winter spring and fall), Grand Canyon (spring raft trip and summer monsoon), Columbia River Gorge (spring), the Eastern Sierra (autumn), Death Valley (winter), Hawaii (Big Island and Maui), and New Zealand’s South Island (winter). Not only do these workshops allow Gary to visit his favorite spots at all the most photogenic times, they enable him to meet some of the most dedicated (and fun!) photographers imaginable. The workshops sell out far in advance, with more than 65% repeat customers.
Sometimes you just need to get dirty.
Gary, I not sure what I enjoy more, your photos or your “pearls of wisdom”. I just know that after reading your blogs I become more focus on shooting what I enjoy shooting.
You are a gifted writer Gary. I hope to some day to be able to join one of your workshops. Take care my friend.
Every time I see your photos on Facebook I want to make it my wallpaper. Is there a way to download a collection of your photos & save?
Thank you. Since is how I make my living, my images are copyrighted——I’m afraid it’s not legal to simply take them and use them without my permission.
Are your photos available to purchase?
Let me know if you don’t find what you’re looking for there.
Hey, I really enjoy your blog so I have nominated you for the Liebster Award.
Love your photos! I am going to attend your Big Island workshop. Just a quick question on your Sony camera. Have you ever run into the dust issue? If so, what would you recommend to clean the sensor safely? Thanks.
Thanks, Sheri. Yeah, dust is a real problem with the mirrorless bodies, but it’s not a show-stopper. The biggest obstacle to overcome is the fear of cleaning your own sensor. Here’s a link that will help: https://www.youtube.com/watch?v=qi6S3jHA21w.
Enjoyed your photos Gary. I’d taken several of the same shots over the years but nowhere near the same skill level. My photos a used to illustrate my stories so it’s nice to see it done right.
I would like to personally congratulate you as your blog Eloquent Nature by Gary Hart has been selected by our panelist as one of the Top 100 Nature Photography Blogs on the web.
Thanks, Anuj. I shared the list with my Facebook followers, who seemed to appreciate it as well. I probably spend way too much time working on my blog, so it’s nice to get a shout-out from time to time.
I live about 30-35 minuets from the Hwy 41 gate to Yosemite. I love the Park.
Though, driving to work in Fresno I have come to love the of the foothills and particularly the Oaks.
Your photographs of the Oaks and hills seem always use a lense with a focal length in the 200mm or more.
Well, I only have the kit lens 18-55mm for an entry level Nikon D3400.
It would be appreciated if you would do a series of blogs on what can be accomplished using a 18-55mm and post photos you have taken when using this type of lens.
Stunning photos and great behind-the-scenes insight on the blog. I enjoy your writing as much as the photos, especially since I can apply some of your lessons learned to my own photography. Thank you Gary! |
Every day about 130 infants, children and teens walk through the doors of Akron Children’s Hospital Pediatrics (ACHP) in Green for a well-child check-up, sick visit or sports physical.
Starting Nov. 17, Akron Children’s will offer specialty services in Warren. Services will include cardiology, neurology, orthopedics, urology, lab and radiology. To celebrate the new space, Akron Children’s hosted a community open house.
Akron Children’s neurology patients will notice a brighter “neighborhood” feel on their next visit with colorful tulips, trees and birds on the walls and, more importantly, a more efficient, streamlined flow for getting in and out of appointments. The redesign of the neurology department is just the start of massive remodeling of the hospital’s neurodevelopmental science center.
Before the big game, football players huddle in the locker room with their coaches, devising plays on a large board in an effort to win the game. But huddling is no longer exclusively for sports. It’s just one of the new strategies being applied at Akron Children’s Hospital to ensure its staff functions as a winning team. |
Most of these pictures were done before scanners or video equipment were easily available on the market. Especially the early ones were created with aide of a draft on some transparent foil and sticking that to the screen. Afterwards the outline was redone in NeoChrome with the mouse. This way you got pretty close to the original proportions and lines. The colouring and dithering was done after the foil had been removed.
Resting Dragon "inspired by Vincente Segrelle's "El Mercenario" Comics"
Conversion from "The Broadsword And The Beast Album Cover by Jethro Tull" |
Clothes, cosmetics, food and drink labelled with a Bud certified organic logo, mean they are grown and made without the use of genetic modification, synthetic pesticides, herbicides, hormones and antibiotics. While providing a higher level of animal welfare, as animals are free to roam and never tested on.
No matter what you are buying, whether it be soap or spinach, choose certified organic to make a difference to the world around us. |
Y.M. Molding Industry Mfg. Inc. |
Bathroom tile design ideas and floor designs for bathrooms tiles. Awesome ideas bathrooms tiles designs 11 27 28 bestpatoghcom. Bathrooms tiles designs ideas luxury bathroom tile design ideas. Astounding bathroom tile designs astounding bathrooms tiles designs. |
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Calling all Fishermen & Fisherwomen! Another great Carolina Beach, NC fishing event, organized by the Southeast King Mackerel Club, is just around the corner. Saturday, October 1st and Sunday, October 2nd, anglers will be baiting up and casting out from local fishing piers on Pleasure Island, in the hopes of winning a variety of prizes. The Southeast King Mackerel Club holds charitable fishing events throughout the year. For registration information, call 910.538.0115. |
Episode 01: Talking Transatlantic Trade: Will the truce hold?
Trade is a top issue in the transatlantic relationship. Since he took office, President Trump has been focused on the U.S. trade deficit and economic competition with Europe, with China, and with most of rest of the world. He imposed tariffs on imported steel and aluminum, prompting a backlash from the European Union, which imposed its own retaliatory measures on U.S. imports. But this was not the end of it and Trump later threatened to impose 25 percent tariffs on automobiles imported from Europe. Where do we stand now? How serious is the danger of trade war? Trump and EU Commission president Jean-Claude Juncker seemed to reach a truce in their July 25 meeting at the White House. How durable will that truce be? How serious is the threat of a new escalation in this trade war? And what would be its consequences?
In this inaugural episode of The Zeitgeist, Jeff Rathke discusses transatlantic trade in the Trump era with Peter Rashish.
Subscribe on iTunes, Spotify, Google Play, Tune In, and Stitcher. |
Come visit Ladybugs Play to test your luck on the wheel. Each family will spin the wheel upon entrance and try to win a prize. Children will also have the chance to search for our hidden leprechaun in hopes of identifying his hiding place and earning a reward. |
Matcha Green Tea, Delivering to the US! Order number # 1622. Beginner's Matcha Set - Free Delivery! x 1. We are going to ship your Matcha in 6 hours (23rd, 18:00 Japan time). Thank you again! |
Online universities offer Associate Degree, Bachelor’s Degree, Master’s Degree and even online certificate programs. This is how education and technology have evolved on-campus to online campus where professional degrees and certifications can be attained.
An Associate Degree comes before a Bachelor’s degree. So it seems logical to earn an Associate Degree first in preparation for the Bachelor’s Degree although this isn’t always the case. Because the decision will still be yours, it depends on what career or fields match your interest, abilities and skills.
There are distance learning universities offering a wide selection of courses online where the curriculum is actually premeditated and enhanced from the conventional to today’s innovative approach. Aspirations to finish Accounting, Business Administration, Communication, Computer Applications, Counter Terrorism Studies, Criminal Justice, Public Health, Retail Management, Paralegal Studies and a whole lot more are just a few of the online Associate Degrees in preparation for further study in the Bachelor’s Degree level but depending on what universities are offering. Generally, there are 8 to 16-week courses available and luckily, you can find Universities online with no application fee, with book grants available and with a strong career and student support system.
Select the program you desire. You need to consider your forte since the key to ensure a productive educational experience is to choose the right degree plan. There are more than 190 online degrees and certificates to choose from and this means a lot of thinking before you decide.
Apply Online. Once you are 100% determined to pursue an associate degree, you must complete and finally submit the online application for admission. Have a list of your previous educational attainment and academic program handy because you will need to provide these to fill in needed information. A student ID and password will be given and will be used every time you log into the e-campus. Typically, the application process takes 10 to 15 minutes.
Complete the orientation. This usually takes 15-20 minutes. Just like enrolling in a conventional school, an online orientation is a must where academic and financial policies as well as Student Rights will be communicated to you. After finishing the orientation, you will be allowed to be admitted to the university that you desire.
After completing the steps above, a member of the enrollment team will either be sending an email or will give you a call regarding the associate degree or course you enrolled in and any other inquiries you may have. |
Gunmen in Pakistan have ambushed a bus and killed 14 passengers after forcing them off the vehicle in the country's south-west, an official said.
Sadaf Khadem, who on Saturday became the first Iranian woman to contest an official boxing bout, has cancelled her return to Tehran after an arrest warrant was issued for her there, her representative said yesterday.
A New Zealand nurse kidnapped by Isil in Syria more than five years ago may still be alive, says her employer the Red Cross, breaking its silence in attempts to find her.
Shamima Begum, the east London schoolgirl who fled to Syria, served in the Islamic State's "morality police" and also tried to recruit other young women to join the jihadist group, well-placed sources have told reporters.
An Israeli spacecraft lost contact with Earth and crashed just moments before it was to land on the moon late yesterday, failing in an ambitious attempt to make history as the first privately funded lunar mission.
People don't call Benjamin Netanyahu "the magician" for nothing. The attorney general had already served notice that he plans to indict the Israeli prime minister on multiple counts of bribery and fraud. A popular former military chief with a reputation for integrity had convinced many in Israel their leader had to go. But the scandals weren't enough to sink Netanyahu's bid to become Israel's longest-serving prime minister. His nationalist base rallied to his aid, cushioning him against likely charges.
EASTERN forces and troops loyal to the Tripoli government fought on the outskirts of Libya's capital yesterday as thousands of residents fled from the battle.
Turkey has warned it could buy jets and additional air defence systems from Russia if it cannot get Patriot missile shields and F-35 jets from Washington, raising the prospect of ever deeper defence ties between Moscow and a Nato member.
Israel's elections were too close to call last night as both Benjamin Netanyahu and the former general trying to unseat him claimed victory.
Israelis began voting in an election on Tuesday that could hand conservative Prime Minister Benjamin Netanyahu a record fifth term or see him dethroned by an ex-general who has pledged clean government and social cohesion.
The Israeli military vehicle rolled slowly through the dark streets of Beit Ummar, a Palestinian town in the southern occupied West Bank.
They could have been a couple in love. And perhaps they were. In their own way. Rami Elhahan and Bassam Aramin. Men in their fifties. All the tell-tell signs were there. The eyes. The eyes. The way they met. Their lightness and the gentleness of touches. The slightest of smiles.
Israeli Prime Minister Benjamin Netanyahu has fallen behind his main challenger in opinion polls ahead of next week's election but still has an easier path to form a government that would keep him in power for a record fifth term.
The children of murdered Saudi Arabian journalist Jamal Khashoggi have received million-dollar houses in the kingdom and monthly five-figure payments as compensation for the killing of their father.
Turkish President Recep Tayyip Erdogan's AK Party has decided to lodge objections to local election results in all 39 Istanbul districts, the 'Hurriyet' newspaper said yesterday, after results showed a narrow lead for the main opposition candidate.
Two Israeli researchers said yesterday they had discovered a network of hundreds of fake Twitter accounts that promoted Israeli Prime Minister Benjamin Netanyahu and attacked his political rivals, a week before the election.
Israeli Prime Minister Benjamin Netanyahu's Likud Party is scrambling to regain lost ground in the polls by trying to paint his main rival as mentally unstable.
A third young Palestinian has died as tens of thousands of protesters gathered near the Israeli border to mark the first anniversary of weekly demos in the Gaza Strip.
A €388m superyacht belonging to a Russian billionaire in one of the world's costliest divorce battles has been released by a Dubai court after being impounded last year.
An airstrike, most likely by the Saudi-led coalition, struck near a rural hospital in northern Yemen, killing seven people including four children, according to the charity Save the Children, which supports the facility.
SchoolsS reopened in southern Israel and traffic clogged Gaza's streets yesterday amid signs of a de-escalation from the most serious cross-border fighting in months.
Israeli Prime Minister Benjamin Netanyahu returned home from Washington yesterday, going straight into military consultations after a night of heavy fire as Israeli aircraft bombed Gaza targets and Palestinian militants fired rockets into Israel.
Ten children, part of the same extended family, were killed by a US air strike in Afghanistan, along with three adult civilians, the United Nations has said.
The Israeli military said it had begun carrying out strikes on Hamas militant targets in the Gaza Strip yesterday, hours after a rocket struck a house in Israel.
Dubai's government has vigorously denied a claim by R&B singer R Kelly that he had planned concerts in the emirate after he had sought permission from a US judge to travel there despite facing sexual-abuse charges.
The US-backed Syrian forces' push to defeat Isil in its last bastion in Syria has been slowed by the presence of civilians and scores of prisoners held by the extremists, officials said.
Israel pounded Gaza with airstrikes hitting 100 locations after militants in the territory fired two rockets towards Tel Aviv, the first time the coastal city has been targeted since the war in 2014.
Isil faced imminent defeat in its final enclave last night as hundreds of jihadist fighters and their families surrendered and the US-backed Syrian Democratic Forces (SDF) claimed the battle was as good as over.
Israeli troops shot dead a Palestinian man after he ran at them with a knife in the Israeli-occupied West Bank yesterday, the military said.
Air strikes by the Saudi-led coalition killed at least 22 civilians, including women and children, in a village in northern Yemen, the United Nations said.
In Baghuz, a single black flag fluttered yesterday in a light afternoon breeze above wrecked vehicles and improvised tents - the last Isil banner flying over the last of its territory east of the Euphrates. The final slice of the terror group's "caliphate" was braced for a fresh assault from Western-backed forces.
U.S-backed fighters will resume their assault on Islamic State's last, small patch of ground in eastern Syria if no more civilians come out by Saturday afternoon, one of their spokesmen said on Friday.
Turkey is running out of time to avert a showdown with the United States over its plans to buy Russian air defences and spurn a counter-offer from its Nato partner, raising the chance of US sanctions against it.
American and British-made bombs may have killed or injured nearly 1,000 civilians, including women and children, in Yemen's four-year conflict, according to a report by human rights groups.
Hundreds of children in Iraq have been charged with links to terrorism, many of them based on confessions obtained through torture, a human rights group has found.
Iraq and the Kurdish regional government have charged hundreds of children with terrorism for alleged affiliation with the Islamic State group, often using torture to coerce confessions, Human Rights Watch said.
US-backed fighters have slowed an offensive to take Isil's last enclave in eastern Syria as a small number of civilians remain there, though fierce fighting continues.
The Dutch man who married British teenager Shamima Begum after she ran away to join Isil now wants to return to the Netherlands with her and their newborn son.
Columns of black smoke billowed from the last small piece of territory held by Isil militants yesterday as US-backed fighters pounded the area with artillery fire and airstrikes.
Shamima Begum's Dutch husband says he wants to return to the Netherlands with her and their newborn son.
We have a remarkably myopic view of terrorist organisations. If they are not on our news channels, the assumption is that they have gone away. Yet the reality is that they are locked into struggles that they see on millenarian timelines in advance of God's greater glory.
Shamima Begum and her newborn baby are thought to have been moved from a Syrian refugee camp after they were "threatened", her family's lawyer has said.
United Nations investigators said Israeli security forces may have committed war crimes and crimes against humanity in killing 189 Palestinians and wounding more than 6,100 at weekly protests in Gaza last year.
At least 10 people were killed and more than 20 injured when a fire broke out at the main train station in Egypt's capital on Wednesday, two medical sources said.
A Saudi princess has been named as the country's first ever female ambassador and its next envoy to the United States.
A devastating fire has raced through densely packed buildings in a centuries-old shopping district in Bangladesh's capital, killing at least 70 people, officials said.
Isil appeared closer to defeat in its last enclave in eastern Syria as a civilian convoy left the besieged area where US-backed forces estimate several hundred jihadists are still holed up.
Around 200 families are trapped in a tiny pocket of land in Syria still controlled by Isil and are being bombed by US-led coalition forces, the UN has said.
Saudi Arabia has agreed to free more than 2,100 Pakistani prisoners as the kingdom's crown prince concluded a visit to its nuclear-armed ally.
One of Israel's most prominent dovish politicians, former foreign minister Tzipi Livni, yesterday said she was leaving politics and warned "democracy is in danger".
Khudida Haji has followed news of the battle for the caliphate's final stronghold more closely than most. For four and-a-half years, he has been hoping for information on family members captured by the jihadists. Out of the five that went missing the day Isil overran the Yazidi homeland of Sinjar, northern Iraq, in 2014, only one returned.
Widowed, homeless, having already lost two young children and utterly alone save for the unborn baby she is soon to give birth to in a Syrian detention camp. So one might expect to detect a note of contrition in the east London accent of teen jihadi bride Shamima Begum.
A senior French officer involved in the fight against the co-called Islamic State terror group in Syria faces punishment - from his own side - after launching a scathing attack on the tactics used by the US-led coalition to defeat Isil in its remaining stronghold of Hajin, a French army spokesman said yesterday.
Iran is planning a "new Holocaust" to destroy Israel, US Vice President Mike Pence claimed at a summit on Middle Eastern security.
Turkish police believe the remains of murdered Saudi journalist Jamal Khashoggi may have been burned, according to a police report.
Displaced by war, starving and living under a tree, 12-year old Fatima Qoba was just 10kg when she was carried into a Yemeni malnutrition clinic.
When London teenager Shamima Begum fled Britain with two other schoolgirls in 2015 to join Isil, it shocked a nation. Now, she wants to go home.
Conjoined twin boys born under blockade in Yemen nearly three weeks ago died at the weekend after attempts to secure their evacuation for potentially life-saving treatment failed.
US-backed troops yesterday battled at Syria's eastern edge to oust Isil from the last square mile of the group's once-sprawling so-called caliphate territory.
The landscape of the eastern Syrian Desert is so flat that from a vantage point 300 yards away you can almost see the entirety of the minuscule last pocket of territory ruled over by the Islamic State of Iraq and the Levant.
Conjoined twin boys born in the chaos of Yemen's war may be evacuated to Saudi Arabia for lifesaving treatment, Saudi authorities said yesterday.
A five-year-old girl was rescued from the rubble of an eight-storey apartment building in Istanbul yesterday, raising the number of survivors of the collapsed structure to 13. At least 10 people have been found dead.
Afghan opposition leaders are set to meet Taliban envoys in a meeting decried by Afghanistan government officials as a betrayal that could let insurgents exploit political divisions.
Pope Francis is opening his historic visit to the United Arab Emirates by meeting with the federation's leader and a group of Muslim elders before addressing faith leaders in a show of religious tolerance in a Muslim region known for its restrictions on religious freedom.
France is planning to repatriate more than 100 Isil suspects from Syria amid fears they could lose track of them after US troops withdraw from the war-torn country.
The United Arab Emirates vice-president boasted of the country's "significant progress" on gender equality as he handed out awards for promoting equal opportunity. The only trouble was - all of them went to men.
A senior US government official, speaking after six days of US peace talks with Afghan Taliban militants, said that Washington was committed to withdrawing foreign forces from Afghanistan to end more than 17 years of war.
The United Nations said shelling of a camp for displaced people in northern Yemen killed eight civilians and wounded 30 others, as the UN envoy arrived yesterday in the capital Sanaa for ceasefire talks with Houthi rebels.
Taliban officials said US negotiators yesterday agreed a draft peace deal stipulating the withdrawal of foreign forces from Afghanistan within 18 months of the agreement being signed.
A Taliban attack in central Afghanistan yesterday killed scores of security personnel, officials said, with some estimates putting the death toll at more than 100, amid government silence about one of the most deadly insurgent attacks in months.
Israeli airstrikes in Syria killed 11 Iranian and pro-Assad fighters early yesterday, in the most serious direct combat between Iranian and Israeli forces in the past six months.
Four American servicemen were killed in an Isil suicide bombing in Syria yesterday, calling into question Donald Trump's decision to withdraw troops before the Islamist group had been defeated.
Severe weather conditions in Syria have killed at least 15 displaced children seeking refuge, over half of whom were in a camp under US control.
Hopes for a fresh truce in Yemen were dealt a blow over the weekend as Houthi rebels boycotted UN-brokered peace talks and threatened further drone strikes against pro-government forces.
The US secretary of state insists he will press Saudi Arabia's crown prince to ensure that the killers of journalist Jamal Khashoggi are held accountable.
US troops have begun withdrawing from Syria, compounding weeks of confusion over Donald Trump's policy in the Middle East and raising fears over the fate of America's Kurdish allies.
An eight-year-old Syrian girl has died in Lebanon after she fell into a swollen river and drowned in the northern town of Minyeh, as refugee camps were battered by extreme winter weather.
An 18-year-old Saudi woman's flight from what she said was an abusive family has rallied opposition to the kingdom's male guardianship system, still a major constraint on women despite the conservative Muslim country's efforts to open up.
Iran will put two satellites into orbit in coming weeks using domestically made missiles, President Hassan Rouhani said yesterday, a week after Washington warned it not to pursue three planned space rocket launches.
Houthi rebels used an explosive-packed drone to target Yemen's military leaders at an army parade yesterday, killing six soldiers and wounding several senior officers.
An 18-year-old Saudi Arabian woman who fled her family over alleged abuse and barricaded herself in a Bangkok airport hotel room in a bid for asylum will be allowed to stay in Thailand while her case is evaluated by the UN refugee agency, immigration authorities said. |
Mountain biking is becoming quite prevalent out here on the Sunshine Coast with some world class facilities. We are very fortunate at Tzoonie that we have direct access to many kilometers of old logging trails ideal for biking or hiking. It is probably just a matter of time before someone develops the suicidal downhill runs that are becoming so popular around the world. There is a biking video on this website that was produced a couple of years ago that illustrates some of the trails and terrain available at the present time. A few days ago we decided to take some bikes out and do an inspection of one main trail to determine whether or not it is passable following the record rainfall we experienced early this spring. Some of the washouts were serious and most certainly offer a challenge to bikers. In spite of the damage, they are spectacular and put natures force into perspective. For guests who would prefer not to push a bike through some difficult terrain, we are suggesting that perhaps a great hike would suffice. We have a couple of destinations for lunch stops that offer incredible scenery and exploration of rain forest, creeks, etc. I am attaching a couple of photos of some of what we discovered during our exploration. |
St John the Baptist Church in Burford undertook a bold new redevelopment project at Warwick Hall to unite the church and local community through the building of a new community facility. The brief was to extend and adapt the listed building to provide a new hall flexible enough to meet the wide ranging needs of today’s end users. The challenge was to deliver a new confident community facility within one of the most historically sensitive church building settings in the country. ClewsLA provided landscape architecture services from initial design through to project completion.
The Warwick Hall has been described by the Bishop of Dorchester as this generation’s ‘gift’ to Burford, building on successive generations of work over centuries in order to build, develop and maintain the church and its setting. |
The third youngest cow to hit 90" T2T at a few weeks over 5 years old! Bronze winner at the 2015 Horn Showcase.
Tip to Tip 70.8750 11/25/2013 70" at 36 months! |
My arms are detaching from my shoulders ;-) It's an amazing piece of art. I'll try to figure out how it works!
Any idea on how transform square to any quadrangle in a linear fashion, pixel -> pixel mapping ?
without going through the code, and knowing Dodicat, he is probably 'just' rotating the end-points through 3D space... the 3D -> 2D(screen) function is pretty simple and fast.
The axial rotate is Rodriue's method.
Dot and cross products I am afraid.
It's the easiest way to do it.
Here are some actual coloured tiles.
But the method is not very analytical.
'rot for the points,crot for the centres.
dodicat wrote: The axial rotate is Rodriue's method.
I'll try all that. Sounds nice. Rodrigue rotation is a must you're right, and not so difficult. I've already used that some times ago.
and Norm is just (K) the unit vector pointing the axis direction.
const as string imgFileName => "planet.bmp"
draw string (10,54), "pixel transfer.."
draw string (SCREENTEST.scrW - 1 - 4 - 12,12), "X"
Very kind, thanks for your attention!
However the value of this showcase here is probably more to be very straighforward with the maths involved. I solved the whole thing with Maxima (a free symbolic math solver), copied it and pasted without any other adjustement.
dim as double rE => 400.
dim as double rA => 100.
There is a nice fading effect by the way. At least could be nice if used correctly. |
INFORMATION INFRASTRUCTURE: NEXT TERROR TARGET?
As the war on terrorism continues, security experts fear that the next battleground could be on the information infrastructure front. Such attacks could disrupt power systems, penetrate financial institutions and disable voice communications systems.
The United States is not producing the talent or investment needed to confront the threat. A shortage of trained information security specialists, poorly designed and tested software, and a lack of funding for security education and research poses serious risks to the country's infrastructure.
We have too few trained individuals who really understand the principles of security and there is almost no national investment in producing more. The incredible growth of our society's deployment of computing has too often been conducted with concerns for issues of safety, security and reliability.
The scope of infrastructure protection is larger than just computer security, and we should be concern with a broader scope, that could be called information assurance. Information assurance also involves issues of physical security, malicious software, privacy, software engineering, database security, network security, computer forensics, intrusion detection, and several other fields.
Anyone who produces computer code or build systems should be aware that some practices are more dangerous than others, could cause harm to the public and infringe on privacy. Engineers in particular should have an awareness that there are areas where their expertise does not reach and they need to call in specialists.
Information security specialists are a scarce commodity. Of the 23 leading U.S. universities involved in computer security research, only 20 Ph.Ds were granted in the last three years. There are probably fewer than 100 faculty in the United States who really have some experience on this field. There are very few who have a broad view and actually can address the whole area.
Instead of finding ways to design new systems resistant to attack, must of the effort is directed at how to apply new patches to the same old, buggy code. This does not serve to fix the long-term problems. The immediate problems of cyber systems can be patched by implementing best practices, but these will not address the fundamental problems of cyberterrorism.
· Interruption: An asset of the system is destroyed or becomes unavailable or unusable. This is referred to as an attack on availability. Examples include destruction of a piece of hardware, such as a hard disk, the cutting of a communication line, or the disabling of the file management system.
· Fabrication: The attacker inserts counterfeit objects into the system. This is referred to as an attack on authenticity. Examples include the insertion of spurious messages in a network or the addition of records to a file.
A useful categorization of these attacks is in terms of passive attacks and active attacks. Passive attacks are in the nature of monitoring of transmissions. The goal of the attacker is to obtain information that is being transmitted. Two types of passive attacks are(1) release of message content;(2) traffic analysis. A release of message content is easily understood. A telephone conversation, an electronic mail message, and a transferred file may contain sensitive or confidential information.
The second passive attack, traffic analysis, is more subtle. Suppose that we had a way of masking the contents of a message or other information traffic so that Cuba, even if they capture the information, could not extract the real information because of the use of encryption. The attacker could after a period of time extract the information and messages, defeating the encryption process.
The second major category of attack is active attacks. These attacks involve some modification of the data stream or the creation of a false stream. It can be subdivided into four categories: masquerade, replay, modification of message, denial of service.
A masquerade takes place when the attacker, under certain entity, pretends to be a different entity, and therefore enabling an authorized entity to obtain extra privileges. Replay involves the passive capture of a data unit and its subsequent retransmission to produce an unauthorized effect.
Modification of service simply means that some portion of a legitimate message is altered, or that messages are delayed or reordered, to produce an unauthorized effect. The denial of service prevents or inhibits the normal use or management of communications facilities. This is a very important and serious possible attack. It could disrupt an entire network, either by disabling the network or by overloading it with messages so as to degrade performance. The attacker could target airports, financial centers, power companies, dams control centers, etc. It is quite difficult to prevent active attacks. The goal is to detect them and to recover from any disruption or delays caused by them.
The objective of the intruder is to gain access to a system or to increase the range of privileges accessible on a system. The intruder must acquired information that should have been protected. In most cases, this information is in the form of a password. The password file can be protected by one way encryption or by limiting the access control to the file. What are the most common techniques used so far to try to break into a system?
Network security has assumed increasing importance. Individuals, corporations, government agencies, must heighten their awareness to protect data and messages, and to protect systems from network-based attacks. The disciplines of cryptography and network security have matured, leading to the development of practical, readily available applications to enforce network security. |
Deliciously Savvy is hosting a super fun Pet Giveaway! 5 Lucky Winners will each receive a New Loot Pets Crate for their own dog! What is Loot Pets you ask? Loot Pets is a Monthly Crate of Geeky Gear and Goods for your Dog! Loot Pets is a Monthly Mystery Crate for Pets and the People That Love Them… delivering apparel, accessories, toys, treats and more! You get a $50+ value in every crate PLUS for each crate purchased… Loot Pets will donate $1 to a local, national, or international animal welfare charity! I just love that! Enter Today & Good Luck from Baby too!
PLUS a Big Thank You to all blogs helping to promote this giveaway with their fabulous readers! Thanks for all you do!
This giveaway will end at 9AM (EST) on 03/16/2016.
Deliciously Savvy did not receive any form of compensation for this giveaway other than receiving this item in order to facilitate my review. Once winner is selected via the Rafflecopter process, the product will be shipped. Winner has 24 hours to respond or another winner will be chosen. No other blog associated with this giveaway is responsible for the product shipment. Loot Pets will be providing the prizes above to the winners. Thank You for stopping by! Any Questions or Concerns email me at mcushing7 (at) hotmail (dot) com.
I would love to get this box for my dog, Señor Mike the Senior Dog, because really I can’t spoil him enough. |
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Unlike the Sola 1200 Spot, the Sola 800 features both flood and spot modes, at 800 lumen and 500 lumen respectively. It makes an absolutely wonderful light for exploring our occasionally dark waters in the Pacific Northwest.
Beach or boat, the perfect bag for any kind of water-related activity. Available in lengths of 36", 26", or 22".
The GoBe 500 Spot is perfect for getting up close and personal, with its 20 degree beam and 500 lumen output. Great for making the colors stand out on smaller creatures such as the shrimp and anemones. |
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found that the prices are very reasonable for good quality products.
I like this fabric store. I can browse in the store without constantly been nag by a sales person. They have good variety of fabric and buttons. Last time I bought fabric to make baby blanket and the sales person helped me to choose and cut it the right size. She was well knowledge and courteous and most importantly not pushy. I will visit this store again.
i like shopping there. They have a good selection of fabrics and the prices are quite reasonable, especially when they have sales. The store is organized and easy to browse. I would recommend shopping here for fabrics. |
Address Inputs. DEVICE/PAGE ADDRESSES (A2, A1, A0): The A2, A1 and. A0 pins are device address inputs that are hard wired for the. 24C eight 2K. 28 Jan Part Number: 24C02WP Function: SERIAL 2K ( x 8) EEPROM Maker: STMicroelectronics. Pinouts: 24C02WP datasheet. Description. 24c02wp Datasheet PDF Download -, 24c02wp data sheet.
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95% Polyester, 5% Elastane. Measurements Not Worn: Total Length: 59cm/23". Measured On UK Size 10. Hand Wash Only. Model Wears UK Size 10. |
The hands-on race car, it is a beauty, use electric tape to decorate it the way you find most pleasing, and add some bows as streamers!
This is what you need: two plastic tubs and lids about 4 cm deep and 12 cm in diameter, you can get them at any delicatessen counter of store, two small canning lids, two roofing nails or screws that have the same approximate size, a steel wire coat hanger from the dry cleaners, some plywood and the car body which is a piece of wood about 2×4 cm and 30 cm long. You can get that as a trimming from a carpenter or ask a friend.
This is one rear wheel, note the lid is on the plastic tub and we have decorated the rims with electric tape. If you pull the take hard it will follow the edge of the lid and the top or the tub. At the centre of the bottom of the tub and the centre of the lid, burn a hole with a heated piece of coat hanger wire. You need some help from an adult, use a candle or small gas burner or barbecue lighter to heat the tip of the wire.
Push the coat hanger axle through the hole and put on a washer made of a short section of a straw.
The tail end of the car body with a slot for the stabilizer The slot is cut into the wood with a saw and it should be about the same width as the thickness of the stabilizer.
The front wheels go on next, they are two canning lids, put the rubber on the outside and use a roofing nail to fix the wheels to the body, use the pre-drilled hole. Make sure that you do not hammer the nails in all the way because the wheels won’t turn then.
The stabilizer goes into the slot at the rear end of the body, make sure the hole in the stabilizer is at the back and at the top, make a little grove with a file in the bottom for the elastic to fit iin when you launch the car. You might sand or file the edge of the this plywood stabilizer a little to better fit into the slot.
The launch pad is a piece of plywood or about 10 centimeters wide and about 45 centimeters long, at one end cut two small slots with a fine saw where the elastic then can be pulled into just as in the illustration. Call this an “Impuls” device and you will impress everybody!
This is the way you launch the car, note the elastic is slung around the bottom of the stabiliser with one hand you hold down the launch pad and with the other you pull the car and elastic all the way back to the end of the launch pad, it might take some tries, but the car should go fast! |
Home » Blogs » Charles Gaba's blog » Dear Democratic Candidates: Time to Play Offense on the ACA.
However, for those of you who aren't doing so yet, you should be aware that your own House Energy & Commerce Committee caucus has thoughtfully posted a handy report breaking down ACA enrollments by every US Congressional District.
There are 25,000 district residents who were previously uninsured but now have quality, affordable health coverage because of the Affordable Care Act.
Overall, the number of uninsured district residents has declined by 27%.
Approximately 22,600 individuals purchased quality, affordable coverage through the new health insurance marketplace, 19,400 enrolled in Medicaid, and 5,400 young adults were able to retain coverage through their parents’ plans. For more than 87% of the individuals enrolled in the health insurance marketplace, financial assistance was available that could reduce the cost of the average plan to $97 per month.
283,000 individuals in the district – including 52,000 children and 122,000 women – now have health insurance that covers preventive services without any co-pays, coinsurance, or deductible.
10,400 seniors in the district received Medicare Part D prescription drug discounts worth $14.1 million.
153,000 seniors in the district are now eligible for Medicare preventive services without paying any co-pays, coinsurance, or deductible.
235,000 individuals in the district are protected by ACA provisions that prevent insurance companies from spending more than 20% of their premiums on profits and administrative overhead. Because of these protections, over 8,400 individuals in the district received approximately $3.4 million in insurance company rebates.
Up to 36,000 children in the district with preexisting health conditions can no longer be denied coverage by health insurers.
235,000 individuals in the district now have insurance that cannot place annual or lifetime limits on their coverage.
First, this only includes private marketplace enrollment figures through April 19th and doesn't account for those who never paid their first month's premium (around 800,000 people). The good news is that, ironically, by my calculations this number should be more than cancelled out by the additional enrollees since April 19th (around 1.3 million nationally, of which around 900K have paid). Even if I'm off by a bit one one side or the other, there's a good 100K cushion there...so yes, the number of paid enrollments as of September should be around the same as the total number listed in your district report.
Second, the Medicaid numbers only include the 6.7 million newly-added enrollees through May 31st, which leaves out an additional 500,000 Medicaid/CHIP enrollees from June....as well as, I'd imagine, another good half million or more from July and August. Whatever "Medicaid/CHIP" number is listed in your district report is almost certainly at least 15% higher by now (for states which have expanded Medicaid) or perhaps 5% higher for states which didn't.
The only quibble I might have with these numbers is the first one, which assumes 60% were previously uninsured based on the KFF study instead of the actual 57%. However, again, those numbers are only based on either 4/19 or 5/31 totals, so I'm certain that the 3% difference has been more than made up by now, making those numbers accurate as of September.
The other slightly squirrelly number is the "young adults on their parents plan" figure, which has been the subject of dispute since it was released. Again, however, this number is from 2 years ago (remember, some ACA provisions have been in effect since 2010), and whatever the actual number was then has certainly gone up since that time.
In other words, no matter what, you should be on very safe ground with the numbers in these reports. Use them.
Should the GOP take control of the Senate, drop-off voters are most concerned that “Republicans will take away a woman’s right to choose and restrict access to birth control” (58 percent rank this very concerning), “Republicans will cut access to health care for 8 million people and let insurance companies refuse to cover people with pre-existing conditions” (58 percent) and “Republicans will cut back workplace protections for women, denying equal pay for equal work” (57 percent)….
Of course, the truth is that it's far more than 8 million people whose healthcare is at risk here. There's also another 6-7 million or so on Medicaid who'd be at risk of having their coverage yanked away as well, not to mention that millions more would be at risk of going back to the "good old days" when insurance companies could kick you to the curb on a whim or tell you to go pound sand if you have a pre-existing condition (that is, something which requires, you know, medical treatment).
The Affordable Care Act (aka "Obamacare", aka "the ACA") isn't a perfect law; no law is. However, it's still a huge improvement over what we had before, and it paves the way for an even better system going forward. That's why I support it, and that's why Democrats should be doing so loud & clear this fall. |
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What Are The Tech MegaTrends?
One person’s perspective: via Tech Crunch as blogged by James Gross. I think this is pretty spot on, although I might rename to merely ‘Social’ MegaTrends. Tech is too expansive in my opinion. |
Lot 176: 14K Heavy Link Charm Bracelet, 172 g.
You are here: Home >> January 26, 2019 Historic Winter Fine Art and Antiques Auction >> Lot 176: 14K Heavy Link Charm Bracelet, 172 g.
14K yellow gold heavy link charm bracelet with six large charms including a bezel set 1851 dated .900 gold U.S. Twenty Dollar coin, Rotary Past Governor mounted lapel pin with .20 ct round diamond, octagonal three-part portrait case, and two circa 1960 commemorative charms. 7 1/2" L with safety chain. Charms – 1 1/8" to 1 5/8" dia. 173.1 grams total. Provenance: Nashville, TN estate. CONDITION: Overall very good condition with some surface wear due to age. |
Dan Musil gives an update on Earthworker’s manufacturing co-op in Morwell.
Earthworker Energy Manufacturing Cooperative passed a major milestone this month with attainment of Watermark certification for our solar hot water products, following satisfactory laboratory tests and a successful factory inspection last Friday. This means we can now start distributing our products country-wide with the legally-required Watermark approval!
Full set-up of the Morwell factory is progressing well, with important electrical work completed last week and commissioning of our newly arrived foaming machine to begin in the coming week. Assistance from a number of Earthworker volunteers has really helped factory coordinator Dave and ex-Everlast worker Anthony keep things moving.
Our aim is to have some full tanks completed by the end of the year, and we’ve had a number of prospective worker-owners visit the factory over the past couple of months in preparation for commencing production proper. Stay tuned for upcoming opportunities for members to pre-order our first batches of solar hot water products in the New Year! |
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Data Science Experience (DSX) is a cloud-based, innovative, end-to-end experience enabling data scientists to learn, create, and collaborate across multidisciplinary teams. Aimed to make data simple and accessible, it merges a powerful set of tools with an online community for data scientists. There are no barriers between the creative and the learning experience, which is exactly how data scientists work. Modern, open, flexible and suitable for a range of users, from expert data scientists to business people, DSX also offers built-in tutorials and on-demand services. |
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If anyone at any time wishes their data to be erased, they may contact the administrator using the above email and request it in writing. Data will be deleted instantly.
Summary - Disclaimer: Since an admission request is sent, it is taken for granted that you have read all information and instructions stated above and that you proceeded with your own and free will. Since this website offers entertaining services only, it is strongly suggested that one does not request admission in case of doubt. |
6300000 Dear Visitor, if you need manual or (and) parts catalog for TEREX Mining excavator, Dump Trucks write to brovertek@gmail.com. Please specify the mining excavator, dump truck model. We'll check our possibilities and inform you. |
Taylor Swift as Rapunzel Is a Disney Dream: See the Annie Leibovitz Photo!
If there was ever any doubt that Taylor Swift led a fairy tale life (with maybe a few more Prince Charmings than we remember), well, the proof is in the picture.
The single once more singer is the latest star to get into character for Disney Parks, starring in a dreamy new print campaign shot by Annie Leibovitz.
And for someone whose hair gets almost as much press as her personal life, it's only fitting as to which character from the Disney archives she was tapped to portray.
Taylor's back in London—find out if a Haylor reunion is in the works!
In the photo, commissioned by Disney and taken on June 20, 2012, in Culver City, the lusciously locked singer is seen hanging out (literally) of a castle's mossy tower, daydreaming, no doubt, of her knight in shining armor prince, while hanging out (not so literally) with every princess's BFF: some birds. |
As many as 978 million people in 20 countries lost money to cybercrime last year, according to a new report by security firm Norton.
The individual impact: Norton says that victims lost an average of $142 to hackers in 2017, and that each victim spent almost 24 hours dealing with the fallout.
How the US was hit: The report claims that 143 million Americans were affected by cybercrime in 2017, losing a total of $19.4 billion.
The big threats: The leading technique used to extort money from consumers was malware—including things like ransomware and cryptojacking. But fraud and password loss were also big hitters.
Why it matters: Norton says that people are overconfident about their own cybersecurity chops. It’s a reminder that we should all be more vigilant online. |
The loss of a key employee, a backlog of old AR, practice growth, expanding or opening a new office locations, current physician billing service problems or a desire to increase cash flow can all lead to a practice needing some extra hands when it comes to their medical billing.
In these types of situations it is critical that the practice is willing to seek help. Trying to get out of these circumstances on your own can be overwhelming. The strongest office managers know there is no shame in asking for a “helping hand” during crunch times.
· The help can be given quickly, from a company that can not only handle the volume of your business, but can do so in a timely manner.
· The “extra hands” cause minimal interruption or risk to your current cash flow and processes.
· The help provides vital value beyond the pressing crisis, and gives you the most value for your dollar. True medical billing experts bring a fresh eye and state-of-the-art knowledge about the billing industry.
The best way to achieve these objectives is to find an outside company who will start by working on the AR that is over 60 days old, in addition to the current dates of services. By working the old AR, this will show the source of lost cash flow and give relief to a great point of aggravation.
Knowing when to seek help, and understanding the type of help you need can turn a potential disaster into a conquest that will please physicians, provide immediate relief for the practice, and set you up for on-going medical billing and collections success.
Applied Medical Systems has been caring for the health of practices for more than 30 years by providing billing, coding and physician practice management services solutions to various healthcare specialties across the U.S.; including hospitals, private practices and emergency department physician groups. |
Have you seen all of the fabulous repurposed crib projects out there? I am amazed by how creative people are. My two-year old has outgrown his crib and he has an amazing triple bed my husband made waiting for him. You can see pictures of the fabulous triple bed and their nautical room here.
I have been dreaming of all the wonderful project that I could make with his old crib. I love repurposed projects! They make me feel so green and we save money. We made two projects with our crib: my husband made something really cool (stay tune for that project) and I made this Photo Wall Display. We bought the crib used and it served it’s purpose for two years and I love that we can still get some use from it.
What you need to do first is take the crib apart. Ours was really easy to take apart with screws on each corner. Then take the crib railing and hang on the wall. I wanted to paint it but my husband knows I like to change the house around so he suggested that we leave it as close to its natural color so that when we are done with it we can put it back together and sell it. He’s knows me well.
We used to hooks that were the perfect size to keep the crib railing up on the wall.
Once you have it on the wall you can start adding your frames. I just used the picture stand attached on the back of the frame to hold the picture up in each slot. No need for nails.
I especially love my DIY $1 frames make over. You will never guess what I used to for the design cover on the frames. Stay tune for the details. |
When I first saw a picture of this undeniably creative hot dog cake, my first reaction was that it would be great to take to a barbecue or other cookout where real hot dogs are already on the menu. The cake is made by sculpting a pound cake into a hamburger bun shape and laying a generously frosted cake hot dog in the middle of it, to be topped with yellow icing “mustard” and gumdrop “onions” and “relish.” It looks oh-so-festive, doesn’t it?
My second reaction to this cake was one of mild disgust because the “hot dog” is made of Twinkies. Twinkies might be tasty (albeit unhealthy) snack cakes on their own, but the idea of a cream-filled hot dog – even one that is just made up to look like a hot dog – is just not appetizing.
Still, I’d definitely attempt this creation with homemade counterparts for a bbq. I’d start with a basic pound cake, carve out the bun, then shape the carved out portion into my “hot dog,” rather than adding Twinkies into the mix. |
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Italy is facing a crisis in the health sector, as around 53,000 nurses are needed across the country. The alert is provided by the Nurses Order, according to which the active nurses are obliged to attend up to 11 patients simultaneously, even in some areas a nurse is responsible for up to 17 patients.
According to the Nursing Order, in the analyzes of all regions of Italy, the most positive results are presented only in some northern provinces where a nurse is registered for three patients. The situation is also worrying in Lombardia, where there are the best hospitals in the national level, but there are about 4800 nurses in these hospitals.
According to the authorities, these figures have serious consequences, as risks increase for the sick but also for the nurses themselves. The fact that about 40 percent of Italian nurses are forced to spend extra hours to cover the needs of patients, explains a lot.
The Order of Nurses requires the issue to be resolved and called an urgent meeting to review this situation with Health Minister Giulia Grillo, and representatives of all Italian provinces. Of course one of the alternatives to solving the crisis is the recruitment of nurses in neighboring countries, such as Albania. |
Of the five phones that Nokia introduced on Sunday here at Mobile World Congress 2018, the Nokia 1 doesn’t stand at the front of the feature queue. Instead, it’s built for anyone who wants an affordable easy-to-use phone, primarily for (gasp) making calls, but still wants to be able to be able to go online, take a photo and listen to tunes.
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Using medical images to seed eye tests.
Teaching robots to do card tricks, and other tricky things.
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Last modified Tue 13 Nov 2018 17:03:44 AEDT . |
Suppose you apply for a big job. A very important job. .
You get your resume together. You make yourself sound indispensable to the new employer. You file an application and several days later the company HR director calls you in for a talk. You are not surprised to learn you’re not the only applicant. The competition is going to be pretty stiff. But you go in and meet the HR person who thinks you’re worth a talk with one of the office managers of this big company. The HR person warns you this person is kind of tough so you ask some friends to speak up on your behalf. They and you are persuasive enough that the office manager sets up a meeting with the Division Director. But the office manager tells you to lose the sport coat, get a suit and a new tie, and shine your shoes. The competition gets tougher the higher you go and you want to make sure you stand out enough to be memorable to the Division Director.
The Division Director takes a good look at you, listens to you state your case, and confers with assistants who have watched the interview. The group likes you but suggests a few tweaks you can make in your presentation and your personal appearance. Maybe they suggest a few additional details would help your resume in your next step.
By now the company’s date for filling this job is getting closer and you are one of a few surviving candidates. The Vice-President of the company is going to meet with all of the finalists and will recommend one to the company President and CEO. To increase the pressure on the finalists, each of them is interviewed as the others watch. The VP has to catch a plane so every extra minute the other candidates take making themselves more impressive means you have less time before the VP leaves to catch the plane. Five minutes before she has to grab her briefcase and bolt out the door, she turns to you. You have only five minutes to sum up everything that justifies your application and your abilities. Five minutes to prove you deserve to be the one who walks into the office of the President and stands at his desk as the newest important employee of the company.
Today is that five minutes for the Missouri legislature.
Today is the last chance for hundreds of bills to make a good enough impression to be sent to the the Governor’s desk, potentially as the newest important laws for Missouri. It’s the last five minutes of the long process and all of the company VPs go out the door at 6 p.m.
. . . . and the applicant’s name is . . wait for it . . . “Bill”. |
Amateur astronomers never know what signals they might pick up.
A satellite lost 13 years ago was just, briefly, found. Now a group of optimistic technicians may have a chance to bring it back into the fold. In January, amateur astronomer Scott Tilley of British Columbia sat in his home, scanning radio frequencies for the U.S. Air Force satellite lost after a January 7 SpaceX launch. Tilley indeed found a lost satellite, but not the one he intended. Using a satellite catalog, he looked up its transmitter frequency and spin rate, and realized he had to alert NASA.
Back in 2005, the space agency suddenly lost contact with IMAGE, the Imager for Magnetopause-to-Aurora Global Exploration, a solar wind observer. Launched in 2000, the mission was already three years past its expected duration. Still, the team decided to try contacting it again two years later, when a 2007 eclipse cutting off the satellite’s solar-powered systems would force a reboot. But IMAGE stayed silent, and NASA declared the spacecraft lost.
Richard Burley, former IMAGE mission director, isn’t sure how the spacecraft came online, but suspects a flaw in the power system, which the team encountered in 2004, could have been triggered again, restarting the computer and putting it into a 72-hour reboot cycle. “We cannot tell exactly how long it has been in this mode,” says Burley, but amateur astronomers have looked back at their data and found IMAGE’s signal as far back as October 2016.
Then on February 25, IMAGE went worryingly quiet again—but not in the same manner it did in 2005, says Burley. He suspects there’s an issue with IMAGE’s spin axis in relation to its medium-gain antenna placement. If NASA can regain control of the spacecraft, it will decide if it can fund a mission restart.
The quixotic tale of a wayward satellite could have a happy ending yet. |
Visual Studio Code>Other>Nav CommentsNew to Visual Studio Code? Get it now.
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In Truckee California 96160, all Medicare supplement standardized plans are offered to qualified individuals under the age of 65 and/or to Medicare-qualified individuals due to disability or end-stage renal disease. In some states, a limited selection of Medicare supplement standardized plans is available to such individuals.
Medicare.gov provides tools that will allow you to compare plans in Truckee CA 96160 Nevada county, but the decision is complicated. Insurance agent Graves recommends that you “work with a licensed insurance agent who can show you both Medicare Supplement Plans and Advantage Plans from multiple companies. Each type has its positives.” The questions to cover, he says: “You need to understand the costs, doctor networks, coverage levels and maximum out-of-pocket for each. Enroll in what suits your situation best.” Organizations such as Consumer Reports and the Medicare Rights Center can also help you research your decision. |
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by Tom Cox MRPharmS, Lead Prison Pharmacist.
It’s long been recognised within prison populations that there’s a high prevalence of substance use disorder in connection with prescription medicines. This is often found alongside problematic polypharmacy situations.[i] My main objective as a Lead Prison Pharmacist is to optimise medicines and resolve problematic polypharmacy, to try and rehabilitate people held in custody.
Medicines optimisation within a prison takes many forms, just as it does in other areas of health care. It starts with comprehensive medicines reconciliation when people arrive at the prison. Compared with the general population, people in custody have often lived chaotic lifestyles, either on the outside of prison, or perhaps in other prisons, so the first step is to understand what they have been taking, and how they have or have not been managing their medicines.
A particular problem we encounter during medicines reconciliation is that when a person arrives in prison, they often have other people’s prescription medicines in their possession, as well as their own. This forms important evidence for any resulting medicines optimisation.
Being a prison pharmacist has its own set of challenges but challenges tend to reap their own rewards. Most of the time I feel like I’m making a positive difference to the lives of some of the most vulnerable in society.
I work in a Category B prison holding 445 adult male prisoners with the majority being Welsh. |
Annita Ray was born in Hudson Falls, New York, possibly in the mid-to-late 1930's. Her first public presence was seen and heard via the movie Shake, Rattle and Rock, filmed during the latter part of 1956. Soon following the movie's release in April 1957 came the release of her first single. After at least 3 more releases on just as many labels, in 1960 Annita hooked up with Ray Anthony and his Bookend Revue, along with Diane Hall. Before year's end 1961, Annita and Diane left the Revue and continued performing as a duo.
After a couple of years, the two women began touring on their own, performing throughout the United States and in many parts of the world, even spending two months in Vietnam in 1967. In the meantime, Annita continued recording on her own with two more singles and an album between the two. Eventually Annita and Diane began recording together for Wand Records as Diane And Annita.
The singer retired in 1970 and later went "full-bore" into commercial real estate. But her voice – the voice that once entertained thousands – started to quiver.
"I would be in high-powered meetings, and people thought I was nervous. But I knew what I was talking about and was completely confident," said Hirsch, who married attorney Ephraim Hirsch in 1976. In August 1984 she began a second career as a licensed Real Estate Broker. |
Patrolling the treacherous waters of Lake Michigan, the dedicated U.S. Coast Guard personnel of Sector Lake Michigan perform their duties with renowned excellence and skill. This precision-struck coin captures the symbols and salutes the dedication of those “Brew-City Maritime Guardians” in a unique and enduring way.
The “Brew-City Maritime Guardians” are headquartered in Milwaukee, WI, or “Brew City,” so named for its renowned brewing industry. Sector Lake Michigan is the largest of all the Coast Guard Sectors in terms of units and the fourth largest in terms of personnel. The sector’s vital mission includes search and rescue, law enforcement, marine safety, aids to navigation and homeland security for all of Lake Michigan and its surrounding waterways.
The obverse features a rendering of the Sector Lake Michigan emblem. The reverse bears the official seal of the U.S. Coast Guard. Struck in a brass alloy, this coin is imbued with enamel on both sides. |
Cosmetic dentistry uses Cosmetic dental bonding to improve smile in Chicago.
Chicago patient had spacing and very round shaped teeth that she felt made her look like a little kid. Dr. Jeffrey Weller placed 4 anterior front teeth cosmetic bonding restorations to improve this patient's smile and confidence. Tooth colored bonding that enhances the full facial aspect of the tooth made a huge difference closing spaces, and improving tooth shape. |
5959 Staples, Suite 211, Corpus Christi, TX 78413.
Call the office for issues regarding HOA code compliance or health and welfare issues (not responsible for 911 emergency response calls).
Kings Crossing Security Officers: Paul Janko, Braden Tackett, Michael Munoz. Send security or safety concerns to these officers via our HOA Security Committee by filling out the Security/Safety Report Form on our Website. If you have a security issue that is not an emergency, please contact the CCPD non-emergency number listed below. If you have an actual security emergency, you should dial 911.
City of Corpus Christi Problem Reporting: use the phone number below to report issues regarding street problems/repair, safety concerns, utilities, animal care, code enforcement, solid waste or graffiti.
Click here for the City of Corpus Christi Website.
Click here to submit a service request to the City. |
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Medically reviewed by Drugs.com. Last updated on Oct 1, 2018.
Dalvance® (dalbavancin) for injection is indicated for the treatment of adult patients with acute bacterial skin and skin structure infections (ABSSSI), caused by susceptible isolates of the following Gram-positive microorganisms: Staphylococcus aureus (including methicillin-susceptible and methicillin-resistant strains), Streptococcus pyogenes, Streptococcus agalactiae, Streptococcus dysgalactiae, Streptococcus anginosus group (including S. anginosus, S. intermedius, S. constellatus) and Enterococcus faecalis (vancomycin susceptible strains).
To reduce the development of drug-resistant bacteria and maintain the effectiveness of Dalvance and other antibacterial agents, Dalvance should be used only to treat infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.
The recommended dosage regimen of Dalvance in patients with normal renal function is 1500 mg, administered either as a single dose, or 1000 mg followed one week later by 500 mg. Dalvance should be administered over 30 minutes by intravenous infusion [see Dosage and Administration (2.3)].
In patients with renal impairment whose known creatinine clearance is less than 30 mL/min and who are not receiving regularly scheduled hemodialysis, the recommended regimen of Dalvance is 1125 mg, administered as a single dose, or 750 mg followed one week later by 375 mg (see Table 1). No dosage adjustment is recommended for patients receiving regularly scheduled hemodialysis, and Dalvance can be administered without regard to the timing of hemodialysis [see Use in Specific Populations (8.5), Clinical Pharmacology (12.3)].
Dalvance (dalbavancin) for injection must be reconstituted with either Sterile Water for Injection, USP, or 5% Dextrose Injection, USP, and subsequently diluted only with 5% Dextrose Injection, USP, to a final concentration of 1 mg/mL to 5 mg/mL.
Reconstitution: Dalvance must be reconstituted under aseptic conditions, using 25 mL of either Sterile Water for Injection, USP, or 5% Dextrose Injection, USP, for each 500 mg vial. To avoid foaming, alternate between gentle swirling and inversion of the vial until its contents are completely dissolved. Do not shake. The reconstituted vial contains 20 mg/mL dalbavancin as a clear, colorless to yellow solution.
Reconstituted vials may be stored either refrigerated at 2 to 8 °C (36 to 46 °F), or at controlled room temperature 20 to 25 °C (68 to 77 °F). Do not freeze.
Dilution: Aseptically transfer the required dose of reconstituted dalbavancin solution from the vial(s) to an intravenous bag or bottle containing 5% Dextrose Injection, USP. The diluted solution must have a final dalbavancin concentration of 1 mg/mL to 5 mg/mL. Discard any unused portion of the reconstituted solution.
Once diluted into an intravenous bag or bottle as described above, Dalvance may be stored either refrigerated at 2 to 8 °C (36 to 46 °F) or at a controlled room temperature of 20 to 25 °C (68 to 77 °F). Do not freeze.
The total time from reconstitution to dilution to administration should not exceed 48 hours.
Like all parenteral drug products, diluted Dalvance should be inspected visually for particulate matter prior to infusion. If particulate matter is identified, do not use.
Administration: After reconstitution and dilution, Dalvance is to be administered via intravenous infusion, using a total infusion time of 30 minutes.
Do not co-infuse Dalvance with other medications or electrolytes. Saline-based infusion solutions may cause precipitation and should not be used. The compatibility of reconstituted Dalvance with intravenous medications, additives, or substances other than 5% Dextrose Injection, USP has not been established.
If a common intravenous line is being used to administer other drugs in addition to Dalvance, the line should be flushed before and after each Dalvance infusion with 5% Dextrose Injection, USP.
Dalvance is supplied in clear glass vials containing sterile powder (white/off-white to pale yellow) equivalent to 500 mg of dalbavancin.
Dalvance is contraindicated in patients with known hypersensitivity to dalbavancin. No data are available on cross-reactivity between dalbavancin and other glycopeptides, including vancomycin.
Serious hypersensitivity (anaphylactic) and skin reactions have been reported in patients treated with Dalvance. If an allergic reaction occurs, treatment with Dalvance should be discontinued. Before using Dalvance, inquire carefully about previous hypersensitivity reactions to glycopeptides, and due to the possibility of cross-sensitivity, exercise caution in patients with a history of glycopeptide allergy [see Patient Counseling Information (17)].
Dalvance is administered via intravenous infusion, using a total infusion time of 30 minutes to minimize the risk of infusion-related reactions. Rapid intravenous infusions of Dalvance can cause reactions that resemble “Red-Man Syndrome,” including flushing of the upper body, urticaria, pruritus, rash, and/or back pain. Stopping or slowing the infusion may result in cessation of these reactions.
In Phase 2 and 3 clinical trials, more Dalvance than comparator-treated subjects with normal baseline transaminase levels had post-baseline alanine aminotransferase (ALT) elevation greater than 3 times the upper limit of normal (ULN). Overall, abnormalities in liver tests (ALT, AST, bilirubin) were reported with similar frequency in the Dalvance and comparator arms [see Adverse Reactions (6.1)].
Clostridium difficile-associated diarrhea (CDAD) has been reported in users of nearly all systemic antibacterial drugs, including Dalvance, with severity ranging from mild diarrhea to fatal colitis. Treatment with antibacterial agents can alter the normal flora of the colon, and may permit overgrowth of C. difficile.
C. difficile produces toxins A and B which contribute to the development of CDAD. Hypertoxin-producing strains of C. difficile cause increased morbidity and mortality, as these infections can be refractory to antibacterial therapy and may require colectomy. CDAD must be considered in all patients who present with diarrhea following antibacterial use. Careful medical history is necessary because CDAD has been reported to occur more than 2 months after the administration of antibacterial agents.
If CDAD is suspected or confirmed, ongoing antibacterial use not directed against C. difficile should be discontinued, if possible. Appropriate measures such as fluid and electrolyte management, protein supplementation, antibacterial treatment of C. difficile, and surgical evaluation should be instituted as clinically indicated.
Prescribing Dalvance in the absence of a proven or strongly suspected bacterial infection is unlikely to provide benefit to the patient and increases the risk of the development of drug-resistant bacteria.
Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in clinical trials of Dalvance cannot be directly compared to rates in the clinical trials of another drug and may not reflect rates observed in practice.
Adverse reactions were evaluated for 2473 patients treated with Dalvance: 1778 patients were treated with Dalvance in seven Phase 2/3 trials comparing Dalvance to comparator antibacterial drugs and 695 patients were treated with Dalvance in one Phase 3 trial comparing Dalvance single and two-dose regimens. A causal relationship between study drug and adverse reactions was not always established. The median age of patients treated with Dalvance was 48 years, ranging between 16 and 93 years. Patients treated with Dalvance were predominantly male (59.5%) and White (81.2%).
Serious adverse reactions occurred in 121/2473 (4.9%) of patients treated with any regimen of Dalvance. In the Phase 2/3 trials comparing Dalvance to comparator, serious adverse reactions occurred in 109/1778 (6.1%) of patients in the Dalvance group and 80/1224 (6.5%) of patients in the comparator group. In a Phase 3 trial comparing Dalvance single and two-dose regimens, serious adverse reactions occurred in 7/349 (2.0%) of patients in the Dalvance single dose group and 5/346 (1.4%) of patients in the Dalvance two-dose group. Dalvance was discontinued due to an adverse reaction in 64/2473 (2.6%) patients treated with any regimen of Dalvance. In the Phase 2/3 trials comparing Dalvance to comparator, Dalvance was discontinued due to an adverse reaction in 53/1778 (3.0%) of patients in the Dalvance group and 35/1224 (2.9%) of patients in the comparator group. In a Phase 3 trial comparing Dalvance single and two-dose regimens, Dalvance was discontinued due to an adverse reaction in 6/349 (1.7%) of patients in the Dalvance single dose group and 5/346 (1.4%) of patients in the Dalvance two-dose group.
The most common adverse reactions in patients treated with Dalvance were nausea (4.7%), headache (3.8%), and diarrhea (3.4%). The median duration of adverse reactions was 3.0 days in patients treated with Dalvance. In the Phase 2/3 trials comparing Dalvance to comparator, the median duration of adverse reactions was 3.0 days for patients in the Dalvance group and 4.0 days in patients in the comparator group. In a Phase 3 trial comparing Dalvance single and two-dose regimens, the median duration of adverse reactions was 3.0 days for patients in the Dalvance single and two-dose group.
Table 2 lists selected adverse reactions occurring in 2% or more of patients treated with Dalvance in Phase 2/3 clinical trials.
* Comparators included linezolid, cefazolin, cephalexin, and vancomycin.
In the Phase 3 trial comparing the single and two-dose regimen of Dalvance, the adverse reaction that occurred in 2% or more of patients treated with Dalvance was nausea (3.4% in the Dalvance single dose group and 2% in the Dalvance two-dose group).
Among patients with normal baseline ALT levels treated with Dalvance 17 (0.8%) had post-baseline ALT elevations greater than 3 times the upper limit of normal (ULN) including five subjects with post-baseline ALT values greater than 10 times ULN. Among patients with normal baseline ALT levels treated with non-Dalvance comparators 2 (0.2%) had post-baseline ALT elevations greater than 3 times the upper limit of normal. Fifteen of the 17 patients treated with Dalvance and one comparator patient had underlying conditions which could affect liver enzymes, including chronic viral hepatitis, history of alcohol abuse and metabolic syndrome. In addition, one Dalvance-treated subject in a Phase 1 trial had post-baseline ALT elevations greater than 20 times ULN. ALT elevations were reversible in all subjects with follow-up assessments. No comparator-treated subject with normal baseline transaminases had post-baseline ALT elevation greater than 10 times ULN.
The following adverse reaction has been identified during post-approval use of dalbavancin. Because the reaction is reported voluntarily from a population of uncertain size, it is not possible to reliably estimate the frequency or establish a causal relationship to drug exposure.
General disorders and administration site conditions: Back pain as an infusion-related reaction [See Warnings and Precautions (5.2)].
Drug-laboratory test interactions have not been reported. Dalvance at therapeutic concentrations does not artificially prolong prothrombin time (PT) or activated partial thromboplastin time (aPTT).
No clinical drug-drug interaction studies have been conducted with Dalvance. There is minimal potential for drug-drug interactions between Dalvance and cytochrome P450 (CYP450) substrates, inhibitors, or inducers [see Clinical Pharmacology (12.3)].
There have been no adequate and well-controlled studies with Dalvance in pregnant women. Dalvance should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
No treatment-related malformations or embryo-fetal toxicity were observed in pregnant rats or rabbits at clinically relevant exposures of dalbavancin. Treatment of pregnant rats with dalbavancin at 3.5 times the human dose on an exposure basis during early embryonic development and from implantation to the end of lactation resulted in delayed fetal maturation and increased fetal loss, respectively [see Data].
The background risk of major birth defects and miscarriage for the indicated population is unknown. However, the background risk in the U.S. general population of major birth defects is 2 to 4% and of miscarriage is 15 to 20% of clinically recognized pregnancies.
No evidence of embryo or fetal toxicity was found in the rat or rabbit at a dose of 15 mg/kg/day (1.2 and 0.7 times the human dose on an exposure basis, respectively). Delayed fetal maturation was observed in the rat at a dose of 45 mg/kg/day (3.5 times the human dose on an exposure basis).
In a rat prenatal and postnatal development study, increased embryo lethality and increased offspring deaths during the first week post-partum were observed at a dose of 45 mg/kg/day (3.5 times the human dose on an exposure basis).
It is not known whether dalbavancin or its metabolite is excreted in human milk; therefore, caution should be exercised when Dalvance is administered to a nursing woman.
The developmental and health benefits of breastfeeding should be considered along with the mother’s clinical need for Dalvance and any potential adverse effects on the breastfed child from Dalvance or from the underlying maternal condition.
Dalbavancin is excreted in the milk of lactating rats.
Safety and efficacy in pediatric patients have not been established.
Of the 2473 patients treated with Dalvance in Phase 2 and 3 clinical trials, 403 patients (16.3%) were 65 years of age or older. The efficacy and tolerability of Dalvance were similar to comparator regardless of age. The pharmacokinetics of Dalvance was not significantly altered with age; therefore, no dosage adjustment is necessary based on age alone.
Dalvance is substantially excreted by the kidney, and the risk of adverse reactions may be greater in patients with impaired renal function. Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection in this age group.
In patients with renal impairment whose known creatinine clearance is less than 30 mL/min and who are not receiving regularly scheduled hemodialysis, the recommended regimen for Dalvance is 1125 mg, administered as a single dose, or 750 mg followed one week later by 375 mg. No dosage adjustment is recommended for patients receiving regularly scheduled hemodialysis, and Dalvance can be administered without regard to the timing of hemodialysis [see Dosage and Administration (2.2), Clinical Pharmacology (12.3)].
No dosage adjustment of Dalvance is recommended for patients with mild hepatic impairment (Child-Pugh Class A). Caution should be exercised when prescribing Dalvance to patients with moderate or severe hepatic impairment (Child-Pugh Class B or C) as no data are available to determine the appropriate dosing in these patients [see Clinical Pharmacology (12.3)].
Specific information is not available on the treatment of overdose with Dalvance, as dose-limiting toxicity has not been observed in clinical studies. In Phase 1 studies, healthy volunteers have been administered cumulative doses of up to 4500 mg over a period of up to 8 weeks, with no signs of toxicity or laboratory results of clinical concern.
Treatment of overdose with Dalvance should consist of observation and general supportive measures. Although no information is available specifically regarding the use of hemodialysis to treat overdose, in a Phase 1 study in patients with renal impairment less than 6% of the recommended dalbavancin dose was removed [see Clinical Pharmacology (12.3)].
Dalvance (dalbavancin) for injection is a lipoglycopeptide synthesized from a fermentation product of Nonomuraea species.
Dalbavancin is a mixture of five closely related active homologs (A0, A1, B0, B1, and B2); the component B0 is the major component of dalbavancin. The homologs share the same core structure and differ in the fatty acid side chain of the N-acylaminoglucuronic acid moiety (R1) structure and/or the presence of an additional methyl group (R2) on the terminal amino group (shown in the Figure 1 and Table 3 below).
The B0 INN chemical name is: 5,31-dichloro-38-de(methoxycarbonyl)-7-demethyl-19-deoxy-56-O-[2-deoxy-2-[(10-methylundecanoyl)amino]-β-D-glucopyranuronosyl]-38-[[3-(dimethylamino)propyl] carbamoyl]-42-O-α-D-mannopyranosyl-15-N-methyl(ristomycin A aglycone) hydrochloride.
Dalvance is supplied in clear glass vials as a sterile, lyophilized, preservative-free, white to off-white to pale yellow solid. Each vial contains dalbavancin HCl equivalent to 500 mg of dalbavancin as the free base, plus lactose monohydrate (129 mg) and mannitol (129 mg) as excipients. Sodium hydroxide or hydrochloric acid may be added to adjust the pH at the time of manufacture. The powder is to be reconstituted and further diluted for IV infusion [see Dosage and Administration (2.3), How Supplied/Storage and Handling (16)].
Dalbavancin is an antibacterial drug [see Microbiology (12.4)].
The antibacterial activity of dalbavancin appears to best correlate with the ratio of area under the concentration-time curve to minimal inhibitory concentration (AUC/MIC) for Staphylococcus aureus based on animal models of infection. An exposure-response analysis of a single study in patients with complicated skin and skin structure infections supports the two-dose regimen [see Dosage and Administration (2.1), Clinical Pharmacology (12.3)].
Cardiac Electrophysiology: In a randomized, positive- and placebo-controlled, thorough QT/QTc study, 200 healthy subjects received dalbavancin 1000 mg IV, dalbavancin 1500 mg IV, oral moxifloxacin 400 mg, or placebo. Neither dalbavancin 1000 mg nor dalbavancin 1500 mg had any clinically relevant adverse effect on cardiac repolarization.
Dalbavancin pharmacokinetic parameters have been characterized in healthy subjects, patients, and specific populations. Pharmacokinetic parameters following administration of single intravenous 1000 mg and 1500 mg doses were as shown in Table 4. The pharmacokinetics of dalbavancin can be described using a three-compartment model.
1 Data from 50 healthy subjects.
2 Data from 12 healthy subjects.
3 Based upon population pharmacokinetic analyses of data from patients, the effective half-life is approximately 8.5 days (204 hours).
4 Data from 49 healthy subjects.
In healthy subjects, dalbavancin AUC0-24h and Cmax both increased proportionally to dose following single IV dalbavancin doses ranging from 140 mg to 1500 mg, indicating linear pharmacokinetics.
The mean plasma concentration-time profile for dalbavancin following the recommended two-dose regimen of 1000 mg followed one week later by 500 mg is shown in Figure 2.
Figure 2. Mean (± standard deviation) dalbavancin plasma concentrations versus time in healthy subjects (n=10) following IV administration over 30 minutes of 1000 mg dalbavancin (Day 1) and 500 mg dalbavancin (Day 8).
No apparent accumulation of dalbavancin was observed following multiple IV infusions administered once weekly for up to eight weeks, with 1000 mg on Day 1 followed by up to seven weekly 500 mg doses, in healthy adults with normal renal function.
Distribution: Dalbavancin is reversibly bound to human plasma proteins, primarily to albumin. The plasma protein binding of dalbavancin is approximately 93% and is not altered as a function of drug concentration, renal impairment, or hepatic impairment. The mean concentrations of dalbavancin achieved in skin blister fluid remain above 30 mg/L up to 7 days (approximately 146 hours) post dose, following 1000 mg IV dalbavancin. The mean ratio of the AUC0-144 hrs in skin blister fluid/AUC0-144 hrs in plasma is 0.60 (range 0.44 to 0.64).
Metabolism: In vitro studies using human microsomal enzymes and hepatocytes indicate that dalbavancin is not a substrate, inhibitor, or inducer of CYP450 isoenzymes. A minor metabolite of dalbavancin (hydroxy-dalbavancin) has been observed in the urine of healthy subjects. Quantifiable concentrations of the hydroxy-dalbavancin metabolite have not been observed in human plasma (lower limit of quantitation = 0.4 µg/mL) [see Drug Interactions (7.2)].
Excretion: Following administration of a single 1000 mg dose in healthy subjects, 20% of the dose was excreted in feces through 70 days post dose. An average of 33% of the administered dalbavancin dose was excreted in urine as unchanged dalbavancin and approximately 12% of the administered dose was excreted in urine as the metabolite hydroxy-dalbavancin through 42 days post dose.
Renal Impairment: The pharmacokinetics of dalbavancin were evaluated in 28 subjects with varying degrees of renal impairment and in 15 matched control subjects with normal renal function.
Following a single dose of 500 mg or 1000 mg dalbavancin, the mean plasma clearance (CLT) was reduced 11%, 35%, and 47% in subjects with mild (CLCR 50 to 79 mL/min), moderate (CLCR 30 to 49 mL/min), and severe (CLCR less than 30 mL/min), renal impairment, respectively, compared to subjects with normal renal function. The clinical significance of the decrease in mean plasma CLT, and the associated increase in AUC0-∞ noted in these pharmacokinetic studies of dalbavancin in subjects with severe renal impairment has not been established [see Dosage and Administration (2.2), Use in Specific Populations (8.6)].
No dosage adjustment is necessary for patients with CLCR greater than 30 mL/min or patients receiving hemodialysis. The recommended regimen for dalbavancin in patients with severe renal impairment who are not receiving regularly scheduled hemodialysis is 1125 mg, administered as a single dose, or 750 mg followed one week later by 375 mg.
Dalbavancin pharmacokinetic parameters in subjects with end-stage renal disease receiving regularly scheduled hemodialysis (three times/week) are similar to those observed in subjects with mild to moderate renal impairment, and less than 6% of an administered dose is removed after three hours of hemodialysis.
Therefore, no dosage adjustment is recommended for patients receiving regularly scheduled hemodialysis, and dalbavancin may be administered without regard to the timing of hemodialysis in such patients [see Dosage and Administration (2.1), Overdosage (10)].
Hepatic Impairment: The pharmacokinetics of dalbavancin were evaluated in 17 subjects with mild, moderate, or severe hepatic impairment (Child-Pugh class A, B or C) and compared to those in nine matched healthy subjects with normal hepatic function. The mean AUC0-336 hrs was unchanged in subjects with mild hepatic impairment compared to subjects with normal hepatic function; however, the mean AUC0-336 hrs decreased 28% and 31% in subjects with moderate and severe hepatic impairment respectively, compared to subjects with normal hepatic function. The clinical significance of the decreased AUC0-336 hrs in subjects with moderate and severe hepatic function is unknown.
No dosage adjustment is recommended for patients with mild hepatic impairment. Caution should be exercised when prescribing dalbavancin to patients with moderate or severe hepatic impairment as no data are available to determine the appropriate dosing.
Gender: Clinically significant gender-related differences in dalbavancin pharmacokinetics have not been observed either in healthy subjects or in patients with infections. No dosage adjustment is recommended based on gender.
Geriatric Patients: Clinically significant age-related differences in dalbavancin pharmacokinetics have not been observed in patients with infections. No dosage adjustment is recommended based solely on age.
Pediatric Patients: The pharmacokinetics of dalbavancin in pediatric populations <12 years of age have not been established.
Nonclinical studies demonstrated that dalbavancin is not a substrate, inhibitor, or inducer of CYP450 isoenzymes. In a population pharmacokinetic analysis, dalbavancin pharmacokinetics were not affected by co-administration with known CYP450 substrates, inducers or inhibitors, nor by individual medications including acetaminophen, aztreonam, fentanyl, metronidazole, furosemide, proton pump inhibitors (omeprazole, esomeprazole, pantoprazole, lansoprazole), midazolam, and simvastatin.
Dalbavancin, a semisynthetic lipoglycopeptide, interferes with cell wall synthesis by binding to the D-alanyl-D-alanine terminus of the stem pentapeptide in nascent cell wall peptidoglycan, thus preventing cross-linking. Dalbavancin is bactericidal in vitro against Staphylococcus aureus and Streptococcus pyogenes at concentrations similar to those sustained throughout treatment in humans treated according to the recommended dosage regimen.
The development of bacterial isolates resistant to dalbavancin has not been observed, either in vitro, in studies using serial passage, or in animal infection experiments.
When tested in vitro, dalbavancin demonstrated synergistic interactions with oxacillin and did not demonstrate antagonistic or synergistic interactions with any of the following antibacterial agents of various classes: gentamicin, vancomycin, levofloxacin, clindamycin, quinupristin/dalfopristin, linezolid, aztreonam, rifampin or daptomycin. The clinical significance of these in vitro findings is unknown.
Dalbavancin has been shown to be active against the following microorganisms, both in vitro and in clinical infections [see Indications and Usage (1)].
The following in vitro data are available, but their clinical significance is unknown. In addition, at least 90% of organisms in the following bacteria exhibit an in vitro minimum inhibitory concentration (MIC) less than or equal to the dalbavancin susceptible breakpoint of 0.25 mcg/mL. However, the safety and efficacy of dalbavancin in treating clinical infections due to these bacteria have not been established in adequate well-controlled clinical trials.
Long-term studies in animals to determine the carcinogenic potential of dalbavancin have not been conducted.
Dalbavancin was not genotoxic in a bacterial reverse mutation (Ames) assay, a mammalian HGPRT gene mutation assay, an in vitro chromosome aberration assay in Chinese Hamster Ovary cells, or an in vivo mouse micronucleus assay.
Impaired fertility in the rat was not observed at a dose of 15 mg/kg/day (1.2 times the human dose on an exposure basis). Reductions in male and female fertility and increased embryo resorptions occurred at a dose of 45 mg/kg/day (3.5 times the human dose on an exposure basis), at which signs of parental toxicity were also observed.
Increases in serum levels of liver enzymes (ALT, AST), associated with microscopic findings in the liver were noted in toxicology studies in rats and dogs where dalbavancin was administered daily for 28 to 90 days. Hepatocellular necrosis was observed in dogs dosed at ≥10 mg/kg/day for longer than 2 months, i.e., at approximately 5 to 7 times the expected human dose on an exposure basis. Histiocytic vacuolation and hepatocyte necrosis were observed in rats dosed daily at 40 and 80 mg/kg/day, respectively, for 4 weeks, (approximately 3 and 6 times the expected human dose on an exposure basis, respectively). In addition, renal toxicity characterized by increases in serum BUN and creatinine and microscopic kidney findings was observed in rats and dogs at doses 5 to 7 times the expected human dose on an exposure basis. The relationship between these findings in the animal toxicology studies after 28 and 90 consecutive days of dosing to the indicated clinical dosing of 2 doses 7 days apart are unclear.
Adult patients with ABSSSI were enrolled in two Phase 3, randomized, double-blind, double-dummy clinical trials of similar design (Trial 1 and Trial 2). The Intent-to-Treat (ITT) population included 1,312 randomized patients. Patients were treated for two weeks with either a two-dose regimen of intravenous Dalvance (1000 mg followed one week later by 500 mg) or intravenous vancomycin (1000 mg or 15 mg/kg every 12 hours, with the option to switch to oral linezolid after 3 days). Dalvance-treated patients with creatinine clearance of less than 30 mL/min received 750 mg followed one week later by 375 mg. Approximately 5% of patients also received a protocol-specified empiric course of treatment with intravenous aztreonam for coverage of Gram-negative pathogens.
The specific infections in these trials included cellulitis (approximately 50% of patients across treatment groups), major abscess (approximately 30%), and wound infection (approximately 20%). The median lesion area at baseline was 341 cm2. In addition to local signs and symptoms of infection, patients were also required to have at least one systemic sign of disease at baseline, defined as temperature 38°C or higher (approximately 85% of patients), white blood cell count greater than 12,000 cells/mm3 (approximately 40%), or 10% or more band forms on white blood cell differential (approximately 23%). Across both trials, 59% of patients were from Eastern Europe and 36% of patients were from North America. Approximately 89% of patients were Caucasian and 58% were males. The mean age was 50 years and the mean body mass index was 29.1 kg/m2.
The primary endpoint of these two ABSSSI trials was the clinical response rate where responders were defined as patients who had no increase from baseline in lesion area 48 to 72 hours after initiation of therapy, and had a temperature consistently at or below 37.6° C upon repeated measurement. Table 5 summarizes overall clinical response rates in these two ABSSSI trials using the pre-specified primary efficacy endpoint in the ITT population.
1 There were 7 patients who did not receive treatment and were counted as non-responders: 6 Dalvance patients (3 in each trial) and one vancomycin/linezolid patient in Trial 2.
2 Patients who died or used non-study antibacterial therapy or had missing measurements were classified as non-responders.
3 The 95% Confidence Interval (CI) is computed using the Miettinen and Nurminen approach, stratified by baseline fever status.
A key secondary endpoint in these two ABSSSI trials evaluated the percentage of ITT patients achieving a 20% or greater reduction in lesion area from baseline at 48-72 hours after initiation of therapy. Table 6 summarizes the findings for this endpoint in these two ABSSSI trials.
1 There were 7 patients (as described in Table 5) who did not receive treatment and were counted as non-responders.
3 The 95% CI is computed using the Miettinen and Nurminen approach, stratified by baseline fever status.
Another secondary endpoint in these two ABSSSI trials was the clinical success rate assessed at a follow-up visit occurring between Days 26 to 30. Clinical Success at this visit was defined as having a decrease in lesion size (both length and width measurements), a temperature of 37.6° C or lower, and meeting pre-specified criteria for local signs: purulent discharge and drainage absent or mild and improved from baseline, heat/warmth & fluctuance absent, swelling/induration & tenderness to palpation absent or mild.
Table 7 summarizes clinical success rates at a follow-up visit for the ITT and clinically evaluable population in these two ABSSSI trials. Note that there are insufficient historical data to establish the magnitude of drug effect for antibacterial drugs compared with placebo at the follow-up visits. Therefore, comparisons of Dalvance to vancomycin/linezolid based on clinical success rates at these visits cannot be utilized to establish non-inferiority.
1 There were 7 patients (as described in Table 5) who did not receive treatment and were counted as failures in the analysis.
2 Patients who died, used non-study antibacterial therapy, or had an unplanned surgical intervention 72 hours after the start of therapy were classified as Clinical Failures.
Table 8 shows outcomes in patients with an identified baseline pathogen, using pooled data from Trials 1 and 2 in the microbiological ITT (microITT) population. The outcomes shown in the table are clinical response rates at 48 to 72 hours and clinical success rates at follow-up (Day 26 to 30), as defined above.
All Dalvance dosing regimens in Trials 1 and 2 consisted of two doses.
1 There were 2 patients in the Dalvance arm with methicillin-susceptible S. aureus at baseline who did not receive treatment and were counted as non-responders/failures.
2 Early Responders are patients who had no increase from baseline in lesion area 48 to 72 hours after initiation of therapy, and had a temperature consistently at or below 37.6° C upon repeated measurement.
Adult patients with ABSSSI were enrolled in a Phase 3, double-blind, clinical trial. The ITT population included 698 patients who were randomized to Dalvance treatment with either a single 1500 mg dose or a two-dose regimen of 1000 mg followed one week later by 500 mg (Trial 3). Patients with creatinine clearance less than 30 mL/min had their dose adjusted (Section 2.2). Approximately 5% of patients also received a protocol-specified empiric course of treatment with intravenous aztreonam for coverage of Gram-negative pathogens. The specific infections and other patient characteristics in this trial were similar to those described above for previous ABSSSI trials.
The primary endpoint in this ABSSSI trial was the clinical response rate where responders were defined as patients who had at least a 20% decrease from baseline in lesion area 48 to 72 hours after randomization without receiving any rescue antibacterial therapy. The secondary endpoint was the clinical success rate at a follow-up visit occurring between Days 26 and 30, with clinical success defined as having at least a 90% decrease from baseline in lesion size, a temperature of 37.6° C or lower, and meeting pre-specified criteria for local signs: purulent discharge and drainage absent or mild and improved from baseline (for patients with wound infections), heat/warmth and fluctuance absent, swelling/induration and tenderness to palpation absent or mild. Table 9 summarizes results for these two endpoints in the ITT population. Note that there are insufficient historical data to establish the magnitude of drug effect for antibacterial drugs compared with placebo at the follow-up visit. Therefore, comparisons between treatment groups based on clinical success rates at this visitcannot be utilized to establish non-inferiority.
1 There were 3 patients in the two-dose group who did not receive treatment and were counted as non-responders.
3 The 95% Confidence Interval (CI) is computed using the Miettinen and Nurminen approach.
Table 10 shows outcomes in patients with an identified baseline pathogen from Trial 3 in the microbiological ITT (microITT) population. The outcomes shown in the table are clinical response rates at 48 to 72 hours and clinical success rates at follow-up (Day 26 to 30), as defined above.
In Trials 1, 2, and 3, all patients had blood cultures obtained at baseline. A total of 40 ABSSSI patients who received Dalvance had bacteremia at baseline caused by one or more of the following bacteria: 26 S. aureus (21 MSSA and 5 MRSA), 6 S. agalactiae, 7 S. pyogenes, 2 S. anginosus group, and 1 E. faecalis. In patients who received Dalvance, a total of 34/40 (85%) were clinical responders at 48-72 hours and 32/40 (80%) were clinical successes at Day 26 to 30.
Unreconstituted Dalvance (dalbavancin) for injection should be stored at 25ºC (77ºF); excursions permitted to 15 to 30ºC (59 to 86ºF) [see USP Controlled Room Temperature].
Patients should be advised that allergic reactions, including serious allergic reactions, could occur, and that serious allergic reactions require immediate treatment. Patients should inform their healthcare provider about any previous hypersensitivity reactions to Dalvance, or other glycopeptides.
Patients should be counseled that antibacterial drugs including Dalvance should only be used to treat bacterial infections. They do not treat viral infections (e.g., the common cold). When Dalvance is prescribed to treat a bacterial infection, patients should be told that although it is common to feel better early in the course of therapy, the medication should be taken exactly as directed. Skipping doses or not completing the full course of therapy may (1) decrease the effectiveness of treatment, and (2) increase the likelihood that bacteria will develop resistance and will not be treatable by Dalvance and other antibacterial drugs in the future.
Patients should be advised that diarrhea is a common problem caused by antibacterial drugs and usually resolves when the drug is discontinued. Sometimes, frequent watery or bloody diarrhea may occur and may be a sign of a more serious intestinal infection. If severe watery or bloody diarrhea develops, patients should contact their healthcare provider.
Dalvance® is a registered trademark of Durata Therapeutics Holding C.V., an Allergan affiliate.
© 2018 Allergan. All rights reserved. |
We just finished our second eight-week session of ballet at the local community center.
...and their baby brother too.
Someone sure does love his new big boy bed.
His sisters think it's pretty cool too.
Lots of growin' up going on around here.
Lots of mixed emotions too.
What's not to love about chocolate chip pancakes?
And what not to love about that face? |
Will the No No Hair Removal System Work for you?
When people see a new hair removal system that they have not tried, one of the first things they usually wonder is if the system will work for them. The No No Hair Removal system is one of these systems, as so many people use it and say it works for them.
Will the No No Hair Removal system work for you, or will you be one of the few people that does not see results?
What color is your hair? -- If you have darker hair that is coarse or thick, you will notice the No No Hair Removal system will work quickly for you. If you have lighter hair, it will take a little more time to work and, if you have blonde hair, it will not work at all. Be sure the type of hair you have is the hair that the manufacturer says the NoNo Hair Removal system works on before you buy it.
Can you commit to daily use? -- Another reason for the No No Hair Removal system working or not working is the amount of commitment you are able to give to using the product.
This means it will generally work for you, just like it works for almost everyone else, if you are willing to commit to using it. That means, while you only have to use it for five to 10 minutes every day, you do have to use it every day for at least the first few weeks.
Long-term use -- The people who say the No No Hair Removal system does not work are usually the ones that do not commit to using it. This is because you will need to use the No No Hair Removal system for several months if you want to get the results promised by the manufacturer. |
There are all sorts of things I learn that don’t have a category. This is where I stuff them. Hopefully they start to form groups over time… but hey, maybe not. |
Most people are familiar with the sudden pain of a muscle cramp. The rapid, uncontrolled contraction, or spasm, happens unexpectedly, with either no stimulation or some trivially small one.
The muscle contraction and pain lasts for several minutes, and then slowly eases. Cramps may affect any muscle, but are most common in the calves, feet, and hands. While painful, they are harmless, and in most cases, not related to any underlying disorder. Nonetheless, cramps and spasms can be manifestations of many neurological or muscular diseases.
The terms cramp and spasm can be somewhat vague, and they are sometimes used to include types of abnormal muscle activity other than sudden painful contraction. These include stiffness at rest, slow muscle relaxation, and spontaneous contractions of a muscle at rest (fasciculation). Fasciculation is a type of painless muscle spasm, marked by rapid, uncoordinated contraction of many small muscle fibers. A critical part of diagnosis is to distinguish these different meanings and to allow the patient to describe the problem as precisely as possible.
Normal voluntary muscle contraction begins when electrical signals are sent from the brain through the spinal cord along nerve cells called motor neurons (Nerve cells within the central nervous system that carry nerve impulses controlling muscle movement). These include both the upper motor neurons within the brain and the lower motor neurons (nerve cells within the central nervous system that carry nerve impulses controlling muscle movement) within the spinal cord and leading out to the muscle. At the muscle, chemicals released by the motor neuron stimulate the internal release of calcium ions from stores within the muscle cell. These calcium ions then interact with muscle proteins within the cell, causing the proteins (actin and myosin) to slide past one another. This motion pulls their fixed ends closer, thereby shortening the cell and, ultimately, the muscle itself. Recapture of calcium and unlinking of actin and myosin allows the muscle fiber to relax.
Abnormal contraction may be caused by abnormal activity at any stage in this process. Certain mechanisms within the brain and the rest of the central nervous system help regulate contraction. Interruption of these mechanisms can cause spasm. Motor neurons that are overly sensitive may fire below their normal thresholds. The muscle membrane itself may be over sensitive, causing contraction without stimulation. Calcium ions may not be recaptured quickly enough, causing prolonged contraction.
Interuption of brain mechanisms and overly sensitive motor neurons may result from damage to the nerve pathways. Possible causes include stroke, multiple sclerosis, cerebral palsy, neurodegenerative diseases, trauma, spinal cord injury, and nervous system poisons such as strychnine, tetanus, and certain insecticides. Nerve damage may lead to a prolonged or permanent muscle shortening called contracture.
Prolonged exercise: Curiously, relaxation of a muscle actually requires energy to be expended. The energy is used to recapture calcium and to unlink actin and myosin. Normally, sensations of pain and fatigue signal that it is time to rest. Ignoring or overriding those warning signals can lead to such severe energy depletion that the muscle cannot be relaxed, causing a cramp. The familiar advice about not swimming after a heavy meal, when blood flow is directed away from the muscles, is intended to avoid this type of cramp. Rigor mortis, the stiffness of a corpse within the first 24 hours after death, is also due to this phenomenon.
Dehydration and Salt Depletion: This may be brought on by protracted vomiting or diarrhea, or by copious sweating during prolonged exercise, especially in high temperatures. Loss of fluids and salts--especially sodium, potassium, magnesium, and calcium--can disrupt ion balances in both muscle and nerves. This can prevent them from responding and recovering normally, and can lead to cramp.
Metabolic disorders that affect the energy supply in muscle. These are inherited diseases in which particular muscle enzymes are deficient. They include deficiencies of myophosphorylase (McArdle's disease), phosphorylase b kinase, phosphofructokinase, phosphoglycerate kinase, and lactate dehydrogenase.
Myotonia: This causes stiffness due to delayed relaxation of the muscle, but does not cause the spontaneous contraction usually associated with cramps. However, many patients with myotonia do experience cramping from exercise. Symptoms of myotonia are often worse in the cold. Myotonias include myotonic dystrophy, myotonia congenita, paramyotonia congenita, and neuromyotonia.
The pain of a muscle cramp is intense, localized, and often debilitating Coming on quickly, it may last for minutes and fade gradually. Contractures develop more slowly, over days or weeks, and may be permanent if untreated. Fasciculations may occur at rest or after muscle contraction, and may last several minutes.
Most cases of simple cramps require no treatment other than patience and stretching. Gently and gradually stretching and massaging the affected muscle may ease the pain and hasten recovery.
More prolonged or regular cramps may be treated with drugs such as carbamazepine, phenytoin, or quinine. Fluid and salt replacement, either orally or intravenously, is used to treat dehydration. Treatment of underlying metabolic or neurologic disease, where possible, may help relieve symptoms.
Cramps may be treated or prevented with Gingko (Ginkgo biloba) or Japanese quince (Chaenomeles speciosa). Supplements of vitamin E, niacin, calcium, and magnesium may also help. Taken at bedtime, they may help to reduce the likelihood of night cramps.
The likelihood of developing cramps may be reduced by eating a healthy diet with appropriate levels of minerals, and getting regular exercise to build up energy reserves in muscle. Avoiding exercising in extreme heat helps prevent heat cramps. Heat cramps can also be avoided by taking salt tablets and water before prolonged exercise in extreme heat. Taking a warm bath before bedtime may increase circulation to the legs and reduce the incidence of night-time leg cramps. |
Common ground : Really moving ; Layers of the earth ; Minerals ; The rock cycle ; Fossils ; Landforms ; Mountains ; North American landscapes ; Field succession ; Loose landscape painting -- 2. After completing Farm Anatomy, she got inspired to continue with what she was doing. See the world in a new way! Additionally, this was beautiful to look at. Take a hike : Anatomy of a deciduous tree ; Anatomy of a trunk ; Leaf identification ; North American trees ; Beautiful bark ; Some flowers, cones, seeds, and fruits of trees ; Printing patterns ; Anatomy of a fern ; Pretty, pretty lichen ; Mysterious mosses ; Waterbears ; Mycelium ; Anatomy of a mushroom ; Marvelous mushrooms ; Rotting log ; Foraging in the forest -- 5. In my childhood I would be obsessed with this book, and I would bring it on every camping trip and road trip. That's precisely what illustrator extraordinaire Julia Rothman and her collaborators Jenny Volvovski and Matt Lamothe celebrate in The Who, the What, and the When- an illuminating inventory of the little-known champions behind a wide range of cultural icons. Just visit my Amazon profile for the link.
It gives a reader friendly general overview of the planet including but not limited to rock cycles, insect anatomy, water bodies, animal adaptation, macro and micro fossils, mushroom anatomy, weather, bird eggs, seashells, and more. Have Such a beautiful fascinating book! If you — or your nature players — have ever wanted to see how mountains are formed, wondered about cloud formations, the life cycle of a mushroom, or the different feathers on a bird, this is the book for you!. Table of Contents Introduction Chapter 1 Common Ground Really Moving - Layers of the Earth - Minerals - The Rock Cycle - Fossils - Landforms - Mountains - North American Landscapes - Field Succession - Loose Landscape Painting Chapter 2 What's Up? In my childhood I would be obsessed with this book, and I would bring it on every camping trip and road trip. Reading this book was kinda like that. She shows it all Some people are blessed with a cool aunt or cool uncle, one that takes you on hikes and catches bugs with you to study. Synopsis See the world in a new way! Remember that fascination with the world around you? Read it, you'd be happy you did : I truly loved this book.
Pint-size epicures will, by contrast, savor the consonant potential of dishes such as tonnato, tournedos and tostadas. Julia Rothman is your cool aunt. Adjust for individual reading level. I have taught most of the content of this book to middle school science classes, and learned even more of it from just growing up in an area where my parents pushed me outside and I had ecologically diverse mountains in my backyard. A set of graphical representations proposed by a scientist. The one rule: Before putting pen to paper, each artist is only allowed to see the panel that precedes his or her own.
It has the same beautiful artwork, but with a wider range of topics which makes sense, since the natural world is so vast and varied. And the content, while it was stuff with which I am generally familiar, would be amazing and accessible for what I imagine is a vast majority of people, especially those who haven't taken a science class in years. Leído en la edición e No es un libro al uso, sino un montón de ilustraciones de la autora, agrupadas por temas, con textos que explican curiosidades. The E-mail message field is required. It is a good idea ruined by a failure of editing. The reason I did not give it five stars is because it would have been nice to have more detailed illustrations.
But it isn't as amazing as all the ratings I've seen make it out to be. Think 's , which is a masterful, humorous, knowledgeable take on these early heroes of computer science. But she is fascinated by food. Come close : Anatomy of a flower ; Anatomy of a bee ; Anatomy of a butterfly ; Metamorphosis ; Plants that attract butterflies ; Beautiful butterflies ; Colorful moths ; Sedges, rushes, grasses ; Grazing edibles ; Incredible insects and bugs abounding ; Spectacular spiders ; Anatomy of an ant -- 4. If you — or your nature players — have ever wanted to see how mountains are formed, wondered about cloud formations, the life cycle of a mushroom, or the different feathers on a bird, this is the book for you! They will get much more out of the book that way. Nature Anatomy is more fun and simple. Combining ink lines with deeply saturated blocks of color, the uncluttered illustrations provide a stylish showcase of architectural structures, which are further explained in an appendix.
See more pictures of the book on my blog. I have taught most of the content of this book to middle school science classes, and learned even more of it from just growing up in an area where my parents pushed me outside and I had ecologically diverse mountains in my backyard. Whether read cover to cover or simply used as a reference, Nature Anatomy is sure to inspire every time it's opened. A little bird told me : Anatomy of a bird ; A bevy of birds ; Kinds of feathers ; Birdcalls ; a variety of nests ; Extraordinary eggs ; Intriguing bird behavior ; Birds of prey ; Owls ; Big birds ; A variety of beaks ; Water birds -- 7. You should buy a copy for the child in you, as well. With time and pressure, the minerals in the water are deposited into the structure of the organism and solidify, leaving behind a three-dimensional fossil. Warhola, who inspired her son Andy's fascination with groceries.
A delicate black line describes the architecture with dexterity, allowing readers a glimpse of wonders that may await on their own journeys as they root for Brick to succeed on hers. I like the ink line styles with filled colours. She shows it all through beautiful illustrations and manages to make you feel such love for the nature around you, however small it is. Reading this book was kinda like that. It makes you wonder why textbooks aren't this fun to read. I read it with my toddler, and it reminded me of so much I used to know. All the bits of information are presented alongside Julia Rothman's simple but beautifully coloured illustrations.
Nature Anatomy was even better! It gives a reader friendly general overview of the planet including but not limited to rock cycles, insect anatomy, water bodies, animal adaptation, macro and micro fossils, mushroom anatomy, weather, bird eggs, seashells, and more. Reading it was a pure joy and it can teach you much about the world you have already explored but hadn't seen. Much like Farm Anatomy, Nature Anatomy is about 60% illustration and 40% text, but the information in this book is more dense and thus, more interesting. One that always seems to know something about everything, you know. I really enjoyed opening it up to read to them and share too. |
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The very talented Dr. April Lindner, Professor of English here at SJU, will read from her new novel LOVE, Lucy on Tuesday, February 24, 2015 during Free Period at the Library. Read on for a brief description of the book, as well as the terrific reviews the book has received.
I could just disappear–lose myself in Florence.
The thought gave Lucy a delicious little shiver.
She could go anywhere, pick a new name for herself, become a whole new person.
She could learn Italian, apply for a job in a cafe, and never go home again.
I could be whoever I want to be.
While backpacking through Florence, Italy, during the summer before she heads off to college, Lucy Sommersworth finds herself falling in love with the culture, the architecture, the food…and Jesse Palladino, a handsome street musician. After a whirlwind romance, Lucy returns home, determined to move on from her “vacation flirtation.” But just because summer is over doesn’t mean Lucy and Jesse are over too.
In this coming of age romance, due out in January 2015, April Lindner perfectly captures the highs and lows of a summer love that might just be meant to last beyond the season.
Career Fair Week is Coming Up!
You have to see NewPages to really appreciate it. NewPages.com is news, information and guides to literary magazines, independent publishers, creative writing programs, alternative periodicals, indie bookstores, writing contests, and more. Their Call for Submissions list is pages long, as well as their Writing Contest opportunities. I’m not a serious writer, but I might just take a swing at one of their offerings. What have I got to lose? Take a look and let me know if anything jumps out at you. I know you have something that would wow those judges!
Merion Matters is the company behind the popular ADVANCE brand, a leader in the healthcare industry for almost 30 years. We’re committed to serving the informational and career needs of millions of doctors, nurses and allied healthcare professionals through a wide range of products and services including magazines, websites, a retail shop, events, custom promotions and communications, hospital shows, conferences and partnerships. We offer corporate clients the opportunity to connect with and influence the healthcare market with effective, targeted and customized media, marketing and merchandise solutions. Join our award-winning team and touch the lives of millions of healthcare professionals. Visit us online at www.advanceweb.com.
We are seeking an Editorial Assistant to assist ADVANCE for Physical Therapy & Rehab Medicine and ADVANCE for Occupational Therapy Practitioners, serving our well-known publication and its supporting Web sites http://physical-therapy.advanceweb.com & http://occupational-therapy.advanceweb.com. ADVANCE for Physical Therapy & Rehab Medicine & ADVANCE for Occupational Therapy Practitioners provides timely, topical, balanced articles to connect rehab professionals with the latest issues surrounding the field.
Create and manage the entire site’s content, including: features, online columns, national news, blogs, resource centers, multimedia, etc.
Coordinate special projects as needed, including digital editions, surveys, patient handouts, conference calendars, etc.
Web and multimedia samples are strongly preferred. |